| 19327606 |
| Inflammation, Takotsubo Cardiomyopathy | Altered Intercellular Communication | Importance of inflammation and neurohumoral activation in Takotsubo cardiomyopathy. | 19327622 |
| Inflammation, Fever, CTCAE | Altered Intercellular Communication | Fever and markers of inflammation persisted despite 3 days of antibiotic therapy. | 19328309 |
| Hyperlipidemia, Myocardial Ischemia, Diabetes Mellitus, Endocrine System Diseases, Chronic liver disease, Hypertension, CTCAE, Epilepsy | Altered Intercellular Communication | Subjects with previous history of diabetes, hypertension, epilepsy, chronic renal or liver disease, hyperlipidemia, ischemic heart disease, endocrine diseases, or prolonged inflammatory conditions were excluded. | 19328732 |
| Inflammation, Obesity, Visceral, osteoclast activating factor | Altered Intercellular Communication | Thus, interventions targeting inflammation related to visceral obesity might help reducing the incidence of POAF. | 19329496 |
| Inflammation | Altered Intercellular Communication | Growing evidence suggests that NGAL may also be involved in cell survival, inflammation, and matrix degradation. | 19329498 |
| Inflammation, Calcinosis, Chronic Kidney Diseases | Altered Intercellular Communication | The expression of markers characteristic for calcification is not different in calcified aorta of CKD patients compared to controls, but in CKD patients, evidence of inflammation, transformation to an osteoblastic phenotype and reduced expression of transglutaminase are also found even in non-calcified aorta. | 19329792 |
| Neurogenic Inflammation, Discitis | Altered Intercellular Communication | In 13 of them (6.2%), a urogenital inflammation caused the spondylodiscitis. | 19330316 |
| Inflammation, Hyperplasia | Altered Intercellular Communication | Microscopically, superficial chronic inflammation with hyperplastic reactive changes and damaged surface was observed. | 19330735 |
| Inflammation, Malignant neoplasm of larynx | Altered Intercellular Communication | Galectin-1 has been found to modulate lymphocyte invasion in inflammation and to be involved in angiogenesis in models, thus prompting examination of its clinical relevance in laryngeal cancer. | 19331133 |
| Degenerative polyarthritis, Inflammation | Altered Intercellular Communication | Magnetic resonance imaging in osteoarthritis: which method best reflects synovial membrane inflammation? | 19332177 |
| Inflammation | Altered Intercellular Communication | Chondral lesions and SM inflammation were macroscopically graded and SM biopsies performed for microscopic scoring. | 19332177 |
| Degenerative polyarthritis, Inflammation | Altered Intercellular Communication | The three MRI approaches used here provided highly reproducible information on SM inflammation near the patella in knee OA. | 19332177 |
| Inflammation, Pain Distress Question, Synovitis, Conjunctival hyperemia, Degenerative polyarthritis | Altered Intercellular Communication | Compared to SMV, MRI synovitis score seems sufficient to assess synovial inflammation but high SMV is an appropriate indicator of vascular congestion, and low SMV reflects pain in knee OA. | 19332177 |
| Inflammation, CAV1 gene, Dental Plaque | Altered Intercellular Communication | The mechanism may be due to increased inflammation resulting in increased plaque burden suggesting a relationship between the immune basis of cellular rejection and CAV. | 19332257 |
| Celiac Disease, Gluten, IGA Glomerulonephritis, Inflammation | Altered Intercellular Communication | It is concluded that approximately one-third of our IgAN patients have a rectal mucosal sensitivity to gluten, but without signs of coeliac disease, and we hypothesize that such sub-clinical inflammation to gluten might be involved in the pathogenesis of IgAN in a subgroup of patients. | 19332868 |
| Inflammation, Spanish Language, Synovitis, Refractory anemias, Tumor necrosis | Altered Intercellular Communication | Despite a similar degree of overall joint inflammation in SpA and RA, SpA synovitis displayed strongly reduced SF levels of M1-derived, but not M2-derived, mediators, such as tumor necrosis factor alpha (TNFalpha), IL-1beta, IL-12p70, and interferon-gamma-inducible protein 10. | 19333931 |
| Refractory anemias, Arthritis | Altered Intercellular Communication | SF levels of M1-derived mediators correlated well with peripheral joint inflammation in RA, but neither these mediators nor IL-1alpha and IL-17 did so in SpA. | 19333931 |
| Cluster, Inflammation, Pain Distress Question, Gout | Altered Intercellular Communication | Cluster analysis and multidimensional scaling showed that these items clustered into 5 concepts (joint inflammation, severity of symptoms, stereotypical nature, pain, and gout archetype) distributed along 2 dimensions (objective to subjective features and general features to specific features of gout). | 19333981 |
| Refractory anemias, Rheumatoid Arthritis, Periodontitis | Altered Intercellular Communication | Rheumatoid arthritis (RA) and periodontitis are common chronic inflammatory conditions. | 19335072 |
| Inflammation, Periodontitis, Alveolar Bone Loss | Altered Intercellular Communication | Chronic periodontitis (CP) exhibits inflammation and alveolar bone loss, and severe forms of periodontitis are suggested to have a genetic basis. | 19335080 |
| Inflammation, Fibrosis Assessment, Alveolar damage | Altered Intercellular Communication | Postmortem examination showed extensive organ fibrosis, including severe diffuse alveolar damage and parenchymal fibrosis, and a notable lack of potentially treatable tissue inflammation. | 19337287 |
| Inflammation, Osteoporosis | Altered Intercellular Communication | Short leukocyte telomere length (TL), low BMD, and osteoporosis have been associated with increased inflammation. | 19338455 |
| Acute infectious disease, Bipolar Disorder | Altered Intercellular Communication | After adjustments for age, sex, acute infection and chronic inflammatory conditions, very high CRP was associated with lower social position, depressive symptoms, physical inactivity, smoking, and alcohol abstinence. | 19339014 |
| Inflammation, Nerve Degeneration | Altered Intercellular Communication | The relation between inflammation and neurodegeneration in multiple sclerosis brains. | 19339255 |
| Inflammation, MS gene, Nerve Degeneration | Altered Intercellular Communication | Some recent studies suggest that in progressive multiple sclerosis, neurodegeneration may occur independently from inflammation. | 19339255 |
| Inflammation, MS gene | Altered Intercellular Communication | We found that pronounced inflammation in the brain is not only present in acute and relapsing multiple sclerosis but also in the secondary and primary progressive disease. | 19339255 |
| Diffuse Axonal Injury, Inflammation, MS gene | Altered Intercellular Communication | A highly significant association between inflammation and axonal injury was seen in the global multiple sclerosis population as well as in progressive multiple sclerosis alone. | 19339255 |
| Inflammation, MS gene, Nerve Degeneration | Altered Intercellular Communication | Our study suggests a close association between inflammation and neurodegeneration in all lesions and disease stages of multiple sclerosis. | 19339255 |
| Inflammation, Chronic Obstructive Airway Disease | Altered Intercellular Communication | Role of TNF-a, sTNF-R55 and sTNF-R75 in inflammation of acute exacerbations of chronic obstructive pulmonary disease. | 19339767 |
| Tumor necrosis, Chronic Obstructive Airway Disease, Inflammation | Altered Intercellular Communication | Although some recent studies have demonstrated the important role of tumor necrosis factor-a (TNF-a) and soluble TNF receptors (sTNF-R) in inflammation of chronic obstructive pulmonary disease, the exact roles of TNF-a and sTNF-R as well as their interaction remained unclear. | 19339767 |
| Inflammation | Altered Intercellular Communication | It was local inflammation but not systemic inflammation that was closely related to airflow limitation. | 19339767 |
| Hyperglycemia, Inflammation | Altered Intercellular Communication | Hyperglycaemia caused by stress and inflammation is common during critical illness. | 19340390 |
| Lewy Bodies, Inflammation | Altered Intercellular Communication | In Lewy body disease, inflammation is discussed to be involved in the pathophysiological cascade. | 19340392 |
| Communicable Diseases, Inflammation, Otosclerosis | Altered Intercellular Communication | Histologic otosclerosis exhibits a strong correlation with MV presence in the bone as a sign of persistent MV infection and related inflammation with TNF-alpha release. | 19340443 |
| Inflammation, Thrombocytopenia, Leukopenia, Lupus Erythematosus, Systemic | Altered Intercellular Communication | Except for high parameters of inflammation, leucopenia and thrombocytopenia, all immunological and laboratory tests for SLE were negative in the onset of the disease. | 19341232 |
| Inflammation, Dental Plaque, Ischemia | Altered Intercellular Communication | Choline has been identified as a promising marker of coronary inflammation, plaque destabilisation and ischaemia. | 19341718 |
| Tissue damage, Inflammation, Cardiovascular Diseases | Altered Intercellular Communication | CRP is a well-known marker of inflammation and tissue damage, widely recognized as a risk predictor of cardiovascular and coronary heart diseases. | 19341863 |
| Inflammation | Altered Intercellular Communication | Substantial evidence suggests inflammation marked by elevated IL-6 levels as a key pathophysiologic factor that contributes to frailty. | 19342252 |
| Inflammation | Altered Intercellular Communication | These findings suggest upregulated monocytic expression of CXCL-10 as an important molecular mechanism that contributes to inflammation activation in frail older adults. | 19342252 |
| Inflammation, Hypertensive (finding), Endothelial dysfunction, diabetic | Altered Intercellular Communication | Endothelial dysfunction, a common feature among hypertensive and type-2 diabetic patients, is associated with inflammation, increased levels of circulating soluble adhesion molecules (SAM), and urinary albumin excretion. | 19342863 |
| Myocarditis | Altered Intercellular Communication | Myocardial inflammation and non-ischaemic heart failure: is there a role for C-reactive protein? | 19343415 |
| Cystic Lesion, Swelling, Dacryoadenitis | Altered Intercellular Communication | Computed tomography scan revealed a cystic lesion in the preseptal tissues with associated soft tissue swelling and lacrimal gland inflammation. | 19343973 |
| Vascular lesions, Encounter due to puberty | Altered Intercellular Communication | The importance of development of such vascular lesions at puberty, due to hormonal changes and increased estrogen levels, is highlighted. | 19343976 |
| Communicable Diseases, Inflammation | Altered Intercellular Communication | During the 4-year observation period, no complications were recorded, no implants were lost, and there was no infection or inflammation. | 19344031 |
| Inflammation, Rheumatoid Arthritis | Altered Intercellular Communication | Inflammation predicts accelerated brachial arterial wall changes in patients with recent-onset rheumatoid arthritis. | 19344530 |
| Inflammation, physiopathological, atherosclerotic | Altered Intercellular Communication | However, early control of inflammation may reduce arterial dysfunction and thus the tendency for atherosclerotic progression. | 19344530 |
| Inflammatory abnormality of the eye | Altered Intercellular Communication | Ocular inflammation scores improved at all time points, and systemic immunosuppressive medication was reduced in 3 of 7 patients taking this at the start of the trial. | 19344827 |
| Chronicity, Inflammation, Varicose Ulcer | Altered Intercellular Communication | Increased levels of TNFalpha in nonhealing venous leg ulcers, especially those of longer duration, implies that excessive inflammation may be causal in wound chronicity and suggests potential therapeutic alternatives. | 19344978 |
| Inflammation, Rheumatoid Factor | Altered Intercellular Communication | Mesenchymal stem cells in rheumatoid synovium: enumeration and functional assessment in relation to synovial inflammation level. | 19346219 |
| Inflammation | Altered Intercellular Communication | To test this hypothesis, the frequency and multipotency of RA synovial MSCs was evaluated in relation to existing synovial inflammation. | 19346219 |
| Inflammation | Altered Intercellular Communication | Synovial inflammation was measured using the arthroscopic visual analogue score (VAS) and further validated using immunohistochemistry and flow cytometry. | 19346219 |
| Inflammation | Altered Intercellular Communication | In RA-MSCs, CD44 levels correlated negatively with inflammation and positively with chondrogenesis (r = -0.830 and r = 0.865, respectively). | 19346219 |
| Refractory anemias, Inflammation | Altered Intercellular Communication | Effective suppression of joint inflammation is therefore necessary for the development of autologous MSC treatments aimed at cartilage regeneration in RA. | 19346219 |
| Retinal Vein Occlusion | Altered Intercellular Communication | Analysis of inflammation- and atherosclerosis-related gene polymorphisms in branch retinal vein occlusion. | 19347053 |
| Inflammation | Altered Intercellular Communication | We examine the relationship between serum titer of anti-CagA-P antibody and gastric inflammation as well as the status of the CagA-P expression in gastric mucosa. | 19347242 |
| Inflammation, Sarcoidosis | Altered Intercellular Communication | Patients with sarcoidosis have elevated levels of several markers of inflammation. | 19347743 |
| Degenerative polyarthritis, Inflammation | Altered Intercellular Communication | Inflammation is currently believed not only to influence clinical manifestations ofosteoarthrosis (OA) but also to be a key pathogenetic link in the chain reaction underlying progress of the disease. | 19348302 |
| Degenerative polyarthritis, Inflammation | Altered Intercellular Communication | Patients with OA and signs of local inflammation undergo a change of algofunctional index and markers of inflammation, such as C-reactive protein (C-RP) and interleukin-6 (IL-6). | 19348302 |
| Degenerative polyarthritis, Pathology | Altered Intercellular Communication | Inflammation markers in patients with isolated disease of large joints are more affected than in women with OA and concomitant pathologies. | 19348302 |
| Osteoarthritis of hip, Inflammation | Altered Intercellular Communication | Increased levels of C-RP and IL-6 in women with gonarthrosis/coxarthrosis confirm the key role of inflammation in the progress of this OA variant. | 19348302 |
| Degenerative polyarthritis, Inflammation | Altered Intercellular Communication | Elevated C-RP and IL-6 levels in patients with OA suggest chronic inflammation in patients with degenerative-dystrophic joint affection. | 19348302 |
| Degenerative polyarthritis, Inflammation, Affection | Altered Intercellular Communication | Aggressive action of inflammation mediators in isolated affection of large joints accounts for the predominance of catabolic processes over anabolic ones which leads to further progress of OA due to low efficiency of the recovery of cartilage tissue and activation of its destruction. | 19348302 |
| Inflammation, atherosclerotic, Chronic Kidney Diseases | Altered Intercellular Communication | Inflammation is a well recognized central component of atherosclerotic processes in chronic kidney disease. | 19349293 |
| ARCN1 gene, Inflammation | Altered Intercellular Communication | Inflammation, most likely involving IL-6, may contribute substantially to PH complicating COPD. | 19349390 |
| Inflammation, Acute myocardial infarction, Necrosis | Altered Intercellular Communication | To investigate urinary methylmalonic acid (uMMA) levels and their relationship with markers of myocyte necrosis and inflammation in patients with acute myocardial infarction (AMI). | 19349725 |
| Infarction, Inflammation | Altered Intercellular Communication | uMMA levels were elevated in patients with AMI and, as such, may be a candidate biochemical indicator of larger infarct size and enhanced inflammation in patients with AMI. | 19349725 |
| Granulomatous inflammation, Typhoid Fever | Altered Intercellular Communication | Typhoid fever may be considered as one of the causes of the differential diagnoses of granulomatous inflammation of the small intestine. | 19349729 |
| Inflammation | Altered Intercellular Communication | For the general surgeon, open cholecystectomy is typically performed when a great degree of inflammation precludes safe laparoscopic removal. | 19350862 |
| Inflammation, Injury of bile duct | Altered Intercellular Communication | The degree of inflammation can also lead to an unacceptable risk of common bile duct injury during the dissection of the triangle of Calot. | 19350862 |
| Inflammation | Altered Intercellular Communication | Our data suggest that partial cholecystectomy in the setting of severe inflammation is a reasonable operation with few long-term sequelae, good clinical results, and satisfactory symptom relief. | 19350862 |
| Xanthogranulomatous cholecystitis, Xanthogranulomatous inflammation | Altered Intercellular Communication | Diagnosis of xanthogranulomatous mastitis can be made by excluding other diseases that elicit xanthogranulomatous inflammation in the breast. | 19351366 |
| Tumor necrosis, Obesity, Abdominal, Inflammation | Altered Intercellular Communication | Impaired preadipocyte differentiation in human abdominal obesity: role of Wnt, tumor necrosis factor-alpha, and inflammation. | 19351711 |
| Inflammation, Obesity | Altered Intercellular Communication | An Ask1-MKK4-p38MAPK/JNK pathway reflects adipocyte stress associated with adipose tissue inflammation, linking visceral adiposity to whole-body insulin resistance in obesity. | 19351724 |
| Inflammation, Lymphoma | Altered Intercellular Communication | Etiology and pathogenesis of these NHLs are unknown, although there might be a possible association between chronic inflammation and lymphomas. | 19352660 |
| Gastrointestinal inflammation | Altered Intercellular Communication | We speculate that TGF-beta1 drives GATA-4 expression during intestinal inflammation, these two components cooperating to promote epithelial healing. | 19353247 |
| Inflammation, Chronic Obstructive Airway Disease | Altered Intercellular Communication | Small airway mucous metaplasia and inflammation in chronic obstructive pulmonary disease. | 19353346 |
| Airway structure | Altered Intercellular Communication | Its relationship to small airway inflammation is poorly defined. | 19353346 |
| ARCN1 gene, Inflammation | Altered Intercellular Communication | CD3(+) and CD8(+) lymphocytic inflammation is related to small airway mucous metaplasia in COPD and may play a causative role in its development. | 19353346 |
| Supranuclear paralysis | Altered Intercellular Communication | A dysfunction of multiple neurotransmitter systems is assumed as a neurochemical basis of the akinetic-rigid syndrome of progressive supranuclear palsy (PSP). | 19353726 |
| Inflammation | Altered Intercellular Communication | In conclusion, probiotic administration in the elderly normalises the response to endotoxin, and modulates activation markers in blood phagocytes, and therefore may help reduce low-grade chronic inflammation. | 19353762 |
| Airway structure, Asthma | Altered Intercellular Communication | Exhaled breath condensate (EBC) pH has been proposed as a biomarker of airway inflammation and oxidative stress in asthma. | 19353777 |
| Airway structure | Altered Intercellular Communication | We also investigated the relationship between EBC pH and biomarkers of airway inflammation and oxidative stress. | 19353777 |
| Inflammation, Dyslipidemias, Diabetes Mellitus | Altered Intercellular Communication | Low-grade inflammation exists in Diabetes mellitus and it is positively related with dyslipidemia (except for HDL cholesterol) in diabetics. | 19356332 |
| Kidney Failure, Chronic, Inflammation | Altered Intercellular Communication | Tartrate-resistant acid phosphatase isoform 5a as an inflammation marker in end-stage renal disease. | 19356371 |
| Kidney Failure, Chronic, Inflammation, Malnutrition | Altered Intercellular Communication | End-stage renal disease (ESRD) is often complicated by chronic inflammation and malnutrition. | 19356371 |
| Kidney Failure, Chronic, Inflammation | Altered Intercellular Communication | We tested whether serum tartrate-resistant acid phosphatase (TRACP) isoform 5a relates to other markers of inflammation in ESRD. | 19356371 |
| Kidney Failure, Chronic, Inflammation | Altered Intercellular Communication | Our findings suggest that TRACP 5a may be a useful marker to estimate the degree of inflammation in ESRD patients on chronic hemodialysis. | 19356371 |
| Communicable Diseases, Inflammation | Altered Intercellular Communication | Adverse events (AE) of infection or inflammation were recorded. | 19356372 |
| Communicable Diseases, Inflammation | Altered Intercellular Communication | Intra-patient Hb variability was greater in the presence of intercurrent conditions, including infection or inflammation (p = 0.0032), blood transfusion (p < 0.0001), hospitalization (p < 0.0001), or hospitalization for cardiovascular (CV) causes (p = 0.0012), than in their absence. | 19356372 |
| Lesion, Inflammation, Toxic effect, Demyelination | Altered Intercellular Communication | We suggest that lesions identified on MRI may be related to a combination of demyelination, inflammation and/or even small-vessel infarction due to local intimal lesions and clotting, secondary to eosinophilic toxicity. | 19356842 |
| Inflammation | Altered Intercellular Communication | Early patchy enhancement did not demonstrate statistically significant correlation with inflammation (P=.28). | 19356874 |
| Inflammation, Chronic disease | Altered Intercellular Communication | The role of inflammation is being considered in chronic diseases. | 19356949 |
| Limbic Encephalitis, Inflammation, T2 and Fluid Attenuated Inversion Recovery MRI, Neoplasms | Altered Intercellular Communication | Diagnoses in the 84 patients (mean age 42 years at MTLE onset) were: limbic encephalitis (LE), n = 23 (27%); HS (unrelated to inflammation), n = 18 (22%); tumours I/II(o), n = 12 (14%); amygdala lesions (increased volume and T2/FLAIR signal), n = 11 (13%); and other, n = 20 (24%). | 19357127 |
| Allergic asthma, Pulmonary Emphysema, Bronchitis, Eosinophilic inflammation | Altered Intercellular Communication | Five clusters were identified with the following characteristics: cluster 1: severe and markedly variable airflow obstruction with features of atopic asthma, chronic bronchitis and emphysema; cluster 2: features of emphysema alone; cluster 3: atopic asthma with eosinophilic airways inflammation; cluster 4: mild airflow obstruction without other dominant phenotypic features; and cluster 5: chronic bronchitis in nonsmokers. | 19357143 |
| Abnormality of the vasculature | Altered Intercellular Communication | Bronchoscopy depicted focal submucosal vascular abnormalities in three patients and only endobronchial inflammation in 32 (91%) patients. | 19357153 |
| Intradermal Route of Drug Administration, Inflammation, Anemia | Altered Intercellular Communication | Among females, the body iron model produced lower estimates of ID prevalence, better predicted anemia, and appeared to be less affected by inflammation than the ferritin model. | 19357218 |
| Inflammation, Hyperhomocysteinemia, Thrombosis, Fibrosis Assessment, Heart failure | Altered Intercellular Communication | Hyperhomocysteinemia, neurohormonal activation, inflammation and altered fibrinolysis have been linked to atherothrombosis as well as to myocardial fibrosis and heart failure. | 19357531 |
| Inflammation, Tumor Cell Invasion, Pneumonia | Altered Intercellular Communication | For autopsy-proven cases of Candida pneumonia, we required microscopic demonstration of yeast invasion in lung autopsy specimens that showed inflammation. | 19357832 |
| Gingivitis, Abscess, Hemorrhage | Altered Intercellular Communication | Intraoral examination revealed severe gingival inflammation, dental abscesses, pathological tooth mobility, bleeding upon probing and attachment loss around several primary teeth. | 19358384 |
| Inflammation, Atherosclerosis | Altered Intercellular Communication | We conclude that continuous infusion of uncontaminated nCRP in apoE (-/-) mice is not associated with increased atherosclerosis, does not alter systemic or local inflammation, and does not affect endothelial activation. | 19359657 |
| Inflammation, Neoplasm Metastasis, Neoplasms | Altered Intercellular Communication | The CXCL12/CXCR4 pathway, which is involved in biological phenomena such as inflammation, lymphoid homing and regeneration, may play an important role in tumor progression and distant metastasis, especially in organ-selective metastasis. | 19360294 |
| Inflammation, Hepatitis, Subretinal route, Hypopyon, Liver Cirrhosis | Altered Intercellular Communication | Three months prior, the patient had undergone liver transplantation for cirrhosis caused by hepatitis C. A slit-lamp examination revealed intense anterior chamber inflammation with hypopyon and fundoscopy showed a yellowish-white subretinal mass lesion in the inferior peripheral fundus. | 19360381 |
| hearing impairment, Fibrosis Assessment | Altered Intercellular Communication | Inflammation during the active stage of the disease and the subsequent fibrosis may cause conductive hearing loss of varying degrees. | 19360433 |
| Inflammation, Primary malignant neoplasm, Neoplasms, Ulcer, Intestines, Small | Altered Intercellular Communication | There were some longitudinal ulcer scars near the tumor, and the chronic inflammation in the small bowel appeared to be associated with the cancer development. | 19360924 |
| Inflammation, Angina, Unstable | Altered Intercellular Communication | Prognostic value of heart rate turbulence and its relation to inflammation in patients with unstable angina pectoris. | 19361591 |
| Inflammation | Altered Intercellular Communication | A relation between cardiac autonomic function and inflammation was shown in several clinical settings. | 19361591 |
| Inflammation, Cachexia | Altered Intercellular Communication | Protein-Energy Wasting and inflammation are the principal risk factors of haemodialysis complications. | 19361965 |
| Inflammation, Malnutrition | Altered Intercellular Communication | We evaluated the reliability of a simple and non expensive test, the Prognostic Inflammatory and Nutritional Index (PINI), for regular screening of maintenance haemodialysis (MHD) patients in order to detect early onset of inflammation and malnutrition. | 19361965 |
| Inflammation, Malnutrition | Altered Intercellular Communication | This simple test appears to be more sensitive and specific of the single components, and not expensive, so that it could be routinely used to identify patients with sub-clinical inflammation and/or malnutrition. | 19361965 |
| vascular inflammations | Altered Intercellular Communication | The objective was to investigate whether dietary intake of plant lignans in a free-living population was associated with markers of vascular inflammation and function. | 19361969 |
| vascular inflammations, Endothelial dysfunction | Altered Intercellular Communication | Higher MAT intakes in the context of a typical Northern Italian diet are associated to lower vascular inflammation and endothelial dysfunction, which could have some implications in CVD prevention. | 19361969 |
| Inflammation, Atrial Fibrillation by ECG Finding | Altered Intercellular Communication | To better understand the relationship between humoral and cellular markers of inflammation and postoperative atrial fibrillation (AF). | 19362015 |
| Inflammation, Fibrosis Assessment | Altered Intercellular Communication | These results suggest that the inflammatory process in lung fibrosis may involve the coronary arteries as a part of a systemic inflammation rather than an idiopathic fibrotic disease confined to the lungs. | 19362458 |
| Inflammation, Metabolic Syndrome X | Altered Intercellular Communication | There was a strong association between inflammation and the metabolic syndrome independent to viral and bacterial infectious burden. | 19362745 |
| Granulomatous inflammation | Altered Intercellular Communication | These giant cells are often observed in granulomatous inflammation against a foreign material. | 19362870 |
| Inflammation, Fetus Small for Gestational Age, Malnutrition | Altered Intercellular Communication | Inflammation (serum C-reactive protein >or= 0.9 mg/dl) was present in 13 (25%) and malnutrition (SGA) in 16 (30.7%) patients. | 19363697 |
| Inflammation, muscle mass | Altered Intercellular Communication | A negative and independent association between muscle mass percentage (BIA) and inflammation was observed. | 19363697 |
| Weakness, Hypopituitarism, Anorexia | Altered Intercellular Communication | Patient 1 was a 54-year-old woman with weakness, loss of appetite, and a hormonal profile suggestive of hypopituitarism. | 19364690 |
| Inflammation, Sore to touch, Exanthema | Altered Intercellular Communication | On physical examination, he had no evidence of skin rash, inflammation, or abnormalities of the testes, although there was marked tenderness on palpation. | 19364694 |
| deficiency aspects, Sexual Dysfunction | Altered Intercellular Communication | For women, hormonal deficiency is not the unique cause of sexual dysfunction. | 19365913 |
| Inflammation, Congenital bronchogenic cyst | Altered Intercellular Communication | The majority of SPNs represent benign processes, including granulotmatous inflammation, bronchogenic cysts and hamartomata. | 19365977 |
| Inflammation, Cardiovascular Diseases | Altered Intercellular Communication | Low-grade chronic inflammation in the relationship between insulin sensitivity and cardiovascular disease (RISC) population: associations with insulin resistance and cardiometabolic risk profile. | 19366964 |
| Inflammation | Altered Intercellular Communication | This study showed that low-grade chronic inflammation is associated with the cardiometabolic risk profile of a healthy population. | 19366964 |
| vascular inflammations, Endothelial dysfunction, Atherosclerosis | Altered Intercellular Communication | Klotho-disrupted mice exhibit atherosclerosis and endothelial dysfunction, which led us to investigate the effect of the Klotho protein on vascular inflammation, particularly adhesion molecule expression. | 19367378 |
| Inflammation | Altered Intercellular Communication | Klotho may have a role in the modulation of endothelial inflammation. | 19367378 |
| Multilineage Dysplasia Present, Inappropriate ADH Syndrome, Leukemia, Myelocytic, Acute | Altered Intercellular Communication | Syndrome of inappropriate antidiuretic hormone secretion associated with acute myeloid leukemia with multilineage dysplasia. | 19367383 |
| Inflammation | Altered Intercellular Communication | These findings suggest chronic inflammation and tissue repair as etiological factors in the development of GCT-ST. | 19367406 |
| Inflammation, Atherosclerosis | Altered Intercellular Communication | Continuous exposure to high grade systemic inflammation may be linked to accelerated atherosclerosis. | 19368280 |
| Inflammation, Obesity, Diabetes Mellitus | Altered Intercellular Communication | Chronic low-grade inflammation is a significant factor in the development of obesity associated diabetes. | 19368716 |
| Inflammation | Altered Intercellular Communication | We conclude that sub-clinical inflammation in T2DM may, in part, be mediated by circulating endotoxin. | 19368716 |
| Airway structure, Asthma | Altered Intercellular Communication | Airway inflammation in patients with asthma with high-fixed or low-fixed plus as-needed budesonide/formoterol. | 19368965 |
| Inflammation, Plaque, Atherosclerotic | Altered Intercellular Communication | Growth arrest-specific gene 6 (GAS6) encodes a vitamin K-dependent protein that regulates inflammation, angiogenesis, and atherosclerotic plaque formation. | 19369636 |
| ARCN1 gene, Inflammation, Chronic Obstructive Airway Disease, Cardiovascular Diseases | Altered Intercellular Communication | Chronic obstructive pulmonary disease (COPD) is recognized as a source of systemic inflammation and is associated with the development of cardiovascular disease. | 19369691 |
| Inflammation, Lymphadenitis | Altered Intercellular Communication | The three false positive PET/CT findings comprised chronic inflammation of mediastinal lymph nodes (n = 2) and anastomosis inflammation (n = 1). | 19370780 |
| Communicable Diseases, Inflammation | Altered Intercellular Communication | This is useful knowledge when CRP is used in the clinic for infection and inflammation status. | 19372230 |
| Inflammation, Hypertrophy | Altered Intercellular Communication | Resistin is associated with inflammation and insulin resistance and exerts direct effects on myocardial cells including hypertrophy and altered contraction. | 19372460 |
| Vitreous Hemorrhage, Intraocular inflammation, Retinal Detachment | Altered Intercellular Communication | Complications included transient vitreous hemorrhage (n = 3), transient intraocular inflammation (n = 3), localized, chronic retinal detachment (n = 1). | 19373124 |
| Intraocular inflammation | Altered Intercellular Communication | After DS, more postoperative adjustments were necessary to lower IOP than after TRAB (85 vs 9.5%, P<0.001), but 7 days after surgery, intraocular inflammation was higher after TRAB (245.8 vs 38.5 ph/ms, P<0.001). | 19373262 |
| Inflammation, Saint Lucia | Altered Intercellular Communication | Acute inflammation was diagnosed in 52% of OC and 28% of LC patients. | 19376278 |
| Inflammation | Altered Intercellular Communication | Peroxisome proliferator-activated receptor alpha (PPARalpha) activators reduce inflammation and oxidative stress. | 19376321 |
| Inflammation, Atrial Fibrillation by ECG Finding | Altered Intercellular Communication | Inflammation plays an important role in the initiation and maintenance of atrial fibrillation (AF). | 19376321 |
| Inflammation, Fibrous | Altered Intercellular Communication | Inflammation and structural factors such as a thin fibrous cap, positive remodeling and large lipid pool have been established as factors associated with coronary plaque instability. | 19376518 |
| Inflammation | Altered Intercellular Communication | Dendritic cells (DC) represent an important and integral part of the immune system and are potent initiators of inflammation. | 19376529 |
| Peripheral Vascular Diseases, Inflammation, Endothelial dysfunction | Altered Intercellular Communication | Nitric oxide: link between endothelial dysfunction and inflammation in patients with peripheral arterial disease of the lower limbs. | 19376804 |
| Peripheral Vascular Diseases, Inflammation, Endothelial dysfunction | Altered Intercellular Communication | To analyse the role of nitric oxide (NO) in peripheral arterial disease (PAD) and its association with inflammation and brachial artery flow-mediated dilation (BAFMD) as an estimation of endothelial dysfunction. | 19376804 |
| AURKAIP1 gene, Autoimmune Pancreatitis, Mikulicz Disease | Altered Intercellular Communication | It includes autoimmune pancreatitis (AIP), Mikulicz's disease, and many other inflammatory conditions affecting multiple organs. | 19377901 |
| Airway structure, ARCN1 gene, Chronic Obstructive Airway Disease | Altered Intercellular Communication | The mechanisms behind airway inflammation in chronic obstructive pulmonary disease (COPD) are still not well understood. | 19378224 |
| Hepatitis C | Altered Intercellular Communication | Malnutrition-inflammation complex syndrome and hepatitis C in maintenance hemodialysis patients. | 19379150 |
| Inflammation, Protein-Energy Malnutrition | Altered Intercellular Communication | Protein-energy malnutrition and inflammation are among the leading causes of poor outcome in hemodialysis patients. | 19379150 |
| Communicable Diseases, Hepatitis C | Altered Intercellular Communication | Hepatitis C virus (HCV) infection is accompanied by elevated proinflammatory mediators, also found in dialysis patients with malnutrition-inflammation complex syndrome. | 19379150 |
| Airway structure | Altered Intercellular Communication | FeNO measured offline is a useful biomarker for airway inflammation in large population-based studies. | 19379527 |
| Inflammation, Chronic sinusitis, Craniosynostosis | Altered Intercellular Communication | Chronic rhinosinusitis (CRS) is characterized by persistent inflammation of the nasal and paranasal mucosa with numerous emigrated leukocytes. | 19379607 |
| Inflammation | Altered Intercellular Communication | Naturally, other mechanisms such as cell inflammation and lack or incapacity of antioxidant enzymes also contribute to the variety of systematic distortions that characterize aging. | 19379805 |
| Myocarditis | Altered Intercellular Communication | Miniaturized extracorporeal circulation can be considered similar to off-pump surgery in terms of systemic inflammatory response, myocardial inflammation and damage, and early outcome. | 19379993 |
| Inflammation | Altered Intercellular Communication | It has clinical signs of severe local inflammation as a result of an exaggerated inflammatory response but neurogenic dysregulation also contributes to it. | 19380284 |
| Inflammation, Complex Regional Pain Syndromes | Altered Intercellular Communication | Although clinically appearing as inflammation in acute stages, local rather than systemic inflammatory responses seem to be relevant in CRPS. | 19380284 |
| Inflammation, deficiency aspects, Malignant Childhood Neoplasm, Communicable Diseases, Calciphylaxis, Obesity, Hypoalbuminemia, Weight decreased, Liver Cirrhosis | Altered Intercellular Communication | Analysis of this case and the 13 previously reported cases of nontraditional calciphylaxis identified the following patient characteristics that highlight clinical situations potentially predisposing to calciphylaxis: hypoalbuminemia, malignant neoplasm, systemic corticosteroid use, anticoagulation with warfarin sodium or phenprocoumon, chemotherapy, systemic inflammation, hepatic cirrhosis, protein C or S deficiency, obesity, rapid weight loss, and infection. | 19380668 |
| Cytomegalovirus Infections, Inflammation, Chlamydia, Endothelial dysfunction, Peripheral Vascular Diseases | Altered Intercellular Communication | Markers of Chlamydia pneumoniae and human cytomegalovirus infection in patients with chronic peripheral vascular disease and their relation to inflammation, endothelial dysfunction and changes in lipid metabolism. | 19381484 |
| Inflammation, Communicable Diseases, Chlamydia, Endothelial dysfunction, Peripheral Vascular Diseases | Altered Intercellular Communication | Our aim was to detect markers of Chlamydia pneumoniae (CPN) and human cytomegalovirus (HCMV) infection in patients with peripheral vascular occlusive disease and to follow markers of inflammation, endothelial dysfunction and lipid metabolism alteration in patients with active infection. | 19381484 |
| Hereditary Diseases, Inflammation, Abdominal Pain | Altered Intercellular Communication | Because the patient's mother complained about chronic and periodic abdominal pain with also persistently elevated inflammatory parameters, the differential diagnosis included hereditary disorders resulting in chronic inflammation. | 19381634 |
| Hereditary Autoinflammatory Diseases, Inflammation, Fever, CTCAE | Altered Intercellular Communication | Hereditary fever syndromes have to be considered in case of chronic unexplained inflammation even if fever is no presenting symptom. | 19381634 |
| ARCN1 gene, Inflammation | Altered Intercellular Communication | As COPD is driven by abnormal pulmonary and systemic inflammation, Toll-like receptors (TLRs) seem to be important. | 19381722 |
| Chronic disease of respiratory system, Inflammation, Colonization, Pneumocystis jiroveci | Altered Intercellular Communication | In patients with chronic respiratory disease, Pneumocystis jirovecii (P. jirovecii) colonization is observed, and may influence disease progression and systemic inflammation. | 19383170 |
| Inflammation, Neurosarcoidosis | Altered Intercellular Communication | MRI and CSF studies are sensitive in the detection of CNS inflammation but lack specificity, making the ascertainment of neurosarcoidosis a clinical challenge. | 19383611 |
| Inflammation | Altered Intercellular Communication | BSS offers a significant advantage over RL in terms of increase in corneal thickness and postoperative inflammation on the first postoperative day in patients undergoing phacoemulsification. | 19384012 |
| Inflammation, Anemia | Altered Intercellular Communication | Anemia persists in many patients following critical illness and is associated with ongoing inflammation, inappropriate erythropoietin response and poor marrow red cell production. | 19384207 |
| Inflammation, Reperfusion Injury | Altered Intercellular Communication | When used to prevent perioperative inflammation and ischemia-reperfusion injury, N-acetylcysteine may inadvertently impair hemostasis. | 19384218 |
| Inflammation | Altered Intercellular Communication | In the suture group, 44.4% of the patients presented inflammation after surgery compared to none in the glue group. | 19384757 |
| Inflammation, Pterygium Of Conjunctiva And Cornea | Altered Intercellular Communication | The use of fibrin glue in pterygium surgery reduces patient symptoms, inflammation and discomfort. | 19384757 |
| Intraocular inflammation | Altered Intercellular Communication | Intraocular inflammation due to previous operation may be a factor inducing opacification through increase of iron-binding capacity in the aqueous humour. | 19384780 |
| Inflammation, Rhabdomyolysis, Kidney Failure | Altered Intercellular Communication | Laboratory findings revealed signs of severe rhabdomyolysis and renal failure as well as elevated markers of inflammation. | 19384813 |
| Inflammation, Oliguria | Altered Intercellular Communication | It is possible that inflammation plays a role in volume decreases associated with normal aging, and that suppressing the inflammatory response moderates this decrease. | 19386384 |
| Refractory anemias, Inflammation, Osteopenia | Altered Intercellular Communication | This study provides strong evidence of a causal link between inflammation and bone loss in RA. | 19386610 |
| Inflammation | Altered Intercellular Communication | One variable that may have contributed to poor outcomes is low drug levels at the site of nerve inflammation. | 19387178 |
| Inflammatory abnormality of the eye, Scleritis | Altered Intercellular Communication | A 78-year-old otherwise healthy woman presented with sudden, severe painful ocular inflammation and marked injection of the right eye over a 3-day period, consistent with scleritis. | 19387243 |
| melanoma, Inflammation, Dental Plaque | Altered Intercellular Communication | The melanoma was treated with iodine 125 plaque radiotherapy, and during surgery, the temporal sclera was markedly edematous and the orbital tissue was fibrotic, presumed related to inflammation. | 19387243 |
| Inflammation, myocardial injury | Altered Intercellular Communication | The combination of elevated CRP and cTnI increased the risk of adverse cardiac events, demonstrating the additive impacts of active inflammation and myocardial injury on prognosis after SES implantation. | 19387251 |
| Colorectal Carcinoma | Altered Intercellular Communication | Comparison of the prognostic value of inflammation-based pathologic and biochemical criteria in patients undergoing potentially curative resection for colorectal cancer. | 19387324 |
| Inflammation | Altered Intercellular Communication | The results of the present study suggest low peritumoral infiltrate (Klintrup criteria) and increased systemic inflammation (mGPS criteria) are linked through the cell-mediated immune system. | 19387324 |
| Inflammation, Carcinoma of lung | Altered Intercellular Communication | We studied the usefulness of the above parameter determination in differentiation between lung cancer and inflammation. | 19388531 |
| Inflammation, Primary malignant neoplasm | Altered Intercellular Communication | The results suggest that activity of the chitotriosidase can not be used to differentiation between inflammation and cancer in lung. | 19388531 |
| Kidney Failure, Chronic | Altered Intercellular Communication | We hypothesized that CCR5 Delta 32 modulates inflammation-driven mortality in patients with ESRD. | 19389855 |
| Inflammation, Carcinogenesis | Altered Intercellular Communication | Further studies are needed to elaborate the role of inflammation in sporadic colorectal carcinogenesis. | 19390125 |
| Inflammatory Bowel Diseases, Miller Dieker syndrome, NCI CTEP SDC Myelodysplastic Syndrome Sub-Category Terminology, Chromosome Aberrations, Gastrointestinal inflammation | Altered Intercellular Communication | Although chromosomal abnormalities in bone marrow (BM) cells, such as trisomy 8, are risk factors for the development of inflammatory bowel diseases (IBD) as well as myelodysplastic syndrome (MDS), the mechanisms of how these cytogenetic abnormalities cause intestinal inflammation are poorly understood. | 19390193 |
| Inflammation | Altered Intercellular Communication | The negative correlation between the ejection fraction of the gallbladder and mucin concentration of gallbladder bile suggests that chronic inflammation of the gallbladder wall is associated with both an impaired motility of the gallbladder and increased mucin release into gallbladder bile. | 19390195 |
| Inflammation | Altered Intercellular Communication | In patients who have had dilatation in the past, inflammation between the esophageal mucosal and muscular layers may make it difficult to perform myotomy. | 19390272 |
| vascular inflammations, Hypertension, CTCAE, Atherosclerosis | Altered Intercellular Communication | Circulating angiopoietin-2 in essential hypertension: relation to atherosclerosis, vascular inflammation, and treatment with olmesartan/pravastatin. | 19390459 |
| vascular inflammations, Hypertension, CTCAE, Cardiovascular Diseases | Altered Intercellular Communication | We have earlier shown that angiotensin II receptor blocker (ARB) reduces mediators of vascular inflammation in hypertension and cardiovascular disease. | 19390459 |
| Inflammation, Left Ventricular Hypertrophy | Altered Intercellular Communication | Chronic subclinical inflammation including the TNFR1-associated system may contribute to LVH. | 19390513 |
| Inflammation, Obesity | Altered Intercellular Communication | Neutrophil activation in morbid obesity, chronic activation of acute inflammation. | 19390527 |
| Obesity | Altered Intercellular Communication | Moreover, because neutrophils have a short life span, this indicates that the chronic inflammatory condition associated with morbid obesity is characterized by a continuous activation of the innate immune system. | 19390527 |
| Celiac Disease, Inflammation, Crypt hyperplasia, Villous atrophy | Altered Intercellular Communication | Celiac disease (CD) is characterized by villous atrophy with crypt hyperplasia and inflammation of the small intestinal mucosa leading to disturbed epithelial transport. | 19391064 |
| Inflammation | Altered Intercellular Communication | To assess whether RDW is associated with plasma markers of inflammation since the mechanism(s) underlying this association remain unknown. | 19391664 |
| Inflammation, Carotid Atherosclerosis | Altered Intercellular Communication | Our findings implicate oxidized Hb as a possible antigenic target of cell-mediated immune responses contributing to inflammation in the pathogenesis of carotid atherosclerosis. | 19393213 |
| Familial neurocardiogenic syncope, Vulvar Vestibulitis | Altered Intercellular Communication | Subsurface inflammation of the introitus, vagina, and cervix only was detected uniquely in women with vulvar vestibulitis syndrome (VVS). | 19393601 |
| Inflammation, Familial neurocardiogenic syncope, Lichen Sclerosus et Atrophicus | Altered Intercellular Communication | A subset of women presenting with VVS exhibited subclinical inflammation of the vulva vestibule and vagina (designated VVS/lichen sclerosus subgroup). | 19393601 |
| Inflammation, Vulva | Altered Intercellular Communication | Enhanced visualization of the genital epithelial subsurface with cross-polarized light may assist in diagnosing subclinical inflammation in vulvar conditions heretofore characterized as sensory syndromes. | 19393601 |
| Inflammation, Corneal edema | Altered Intercellular Communication | The visual acuity, degree of corneal edema, inflammation, and intraocular pressure (IOP) were measured. | 19393885 |
| Inflammation, PDR gene | Altered Intercellular Communication | Appropriate control of postsurgical inflammation is necessary in phacovitrectomy for PDR. | 19393886 |
| Inflammation, Kidney Failure, Acute, Blood Coagulation Disorders, Aortic Aneurysm, Thoracoabdominal | Altered Intercellular Communication | Systemic inflammation, coagulopathy, and acute renal insufficiency following endovascular thoracoabdominal aortic aneurysm repair. | 19394543 |
| Aneurysm, Malignant Neoplasms | Altered Intercellular Communication | Although previous studies have shown that PET/CT might affect patient selection based on aneurysm wall inflammation, our preliminary results show a big impact on patient management as a result of the sensitivity of PET/CT for detecting malignancy. | 19394556 |
| Inflammation, Comorbidity, Chronic Kidney Diseases | Altered Intercellular Communication | Patients with chronic kidney disease stage 5 have high comorbidity and are prone to inflammation that may contribute to the high cardiovascular mortality risk. | 19394732 |
| Inflammation, Comorbidity | Altered Intercellular Communication | Comorbidity and clinical events are strongly associated with inflammation in hemodialysis patients. | 19394732 |
| Rheumatoid Arthritis, Acute inflammation, Lymphopenia, Lupus Erythematosus | Altered Intercellular Communication | Autoantibodies against galectin-8: their specificity, association with lymphopenia in systemic lupus erythematosus and detection in rheumatoid arthritis and acute inflammation. | 19395456 |
| Autoimmune Diseases, Acute inflammation, Lupus Erythematosus, Systemic | Altered Intercellular Communication | This study thus establishes occurrence of specific anti-Gal-8 autoantibodies in autoimmune rheumatic diseases and in acute inflammation, with an apparent association to a clinical subset in SLE. | 19395456 |
| Inflammation, Lower Urinary Tract Symptoms, Benign prostatic hypertrophy | Altered Intercellular Communication | Inflammation may play a role in the development of benign prostatic hyperplasia and/or lower urinary tract symptoms (LUTS). | 19395697 |
| Mixed Salivary Gland Tumor, Adenolymphoma, Inflammation | Altered Intercellular Communication | The results of ultrasound-guided fine-needle aspiration biopsy (FNAB) (n = 9) and core-needle biopsy (CNB) (n = 3) were Warthin tumor in 10 cases, and pleomorphic adenoma and chronic inflammation in one each. | 19396445 |
| Mixed Salivary Gland Tumor, Adenolymphoma, Inflammation | Altered Intercellular Communication | SUV(max) was 7.0-21.0 g/mL (average 13.7 g/mL) for Warthin tumor, 6.8 g/mL for pleomorphic adenoma, and 7.3 g/mL for chronic inflammation. | 19396445 |
| Inflammation | Altered Intercellular Communication | Each FDG-avid focus corresponded to ovoid (n = 11) or lobulated (n = 1) hypoechoic mass on grayscale ultrasonography (US) and hypervascular mass, except one with chronic inflammation, on power Doppler (PD) US. | 19396445 |
| Sepsis, Inflammation | Altered Intercellular Communication | TREM-1 is up-regulated in PBMC of AC patients, and has higher sensitivity and specificity than other clinical inflammation markers, suggesting its importance in AC-induced sepsis. | 19396532 |
| Intraocular inflammation, Neoplasms | Altered Intercellular Communication | No significant tumor neovascularization or intraocular inflammation was noted. | 19396801 |
| Inflammation, Dermatitis | Altered Intercellular Communication | The lesion was initially thought to be an area of lichenified dermatitis; however, treatment with even super-potent topical corticosteroids did not significantly improve the inflammation. | 19397564 |
| Abdominal wall structure, Rupture | Altered Intercellular Communication | The increment of MMPs in the absence of a counterbalance by TIMPs, together with an ongoing de-regulated inflammatory signalling, may contribute in inducing a functional defect of the ECM network by post-translational mechanisms, which may trigger abdominal wall tissue loss and eventual rupture. | 19397782 |
| Communicable Diseases, Inflammation, Aneurysm | Altered Intercellular Communication | The serum copper/zinc ratio, a well-known marker of ongoing infection and/or inflammation, was higher (26%, p<0.001) in aneurysm patients. | 19398057 |
| Communicable Diseases, Inflammation | Altered Intercellular Communication | The results are compatible with active infection and/or inflammation, possibly initiated by C. pneumoniae. | 19398057 |
| Inflammation, Acute Coronary Syndrome | Altered Intercellular Communication | Several markers of systemic inflammation seem to play an active role in the pathophysiology of acute coronary syndrome and its evolution. | 19398086 |
| Meningism, Inflammation | Altered Intercellular Communication | The symptoms of the disease suddenly became aggravated and took a form of meningeal syndrome without inflammation of cerebrospinal fluid. | 19399363 |
| Inflammatory abnormality of the eye, Conjunctival scar | Altered Intercellular Communication | Later, he developed ocular inflammation with conjunctival scarring and synechiae formation as well as episodes of vesicles. | 19399380 |
| Necrotizing granulomatous inflammation, Calcinosis | Altered Intercellular Communication | All 13 pilomatrixomas demonstrated the characteristic histology with areas of basophilic islands, shadow cells, calcification and a chronic granulomatous inflammation with foreign body giant cells in varying amounts. | 19399712 |
| Intestinal metaplasia, Inflammation | Altered Intercellular Communication | p120 (CagA) seropositivity was significantly more often present in patients with higher activity grade in the antrum (P = 0.025), p30 in patients with greater inflammation in the antrum (P = 0.025) and the corpus (P = 0.010), p33 in patients with greater inflammation in the corpus (P = 0.050), and p19 (OMP) in patients with lower intestinal metaplasia grades in the corpus (P = 0.025). | 19399945 |
| Airway structure | Altered Intercellular Communication | However, the role of OPN in eosinophilic airway inflammation is unclear. | 19400906 |
| Airway structure | Altered Intercellular Communication | To elucidate the role of OPN in eosinophilic airway inflammation. | 19400906 |
| Inflammation | Altered Intercellular Communication | There is growing evidence that inflammation plays an important role in atherogenesis. | 19400931 |
| Inflammation, Osteitis, Failure (biologic function) | Altered Intercellular Communication | The possibility of local osteitis can cause persistent mucosal inflammation and lead to failure of treatment. | 19401044 |
| Inflammation, Malignant neoplasm of endometrium | Altered Intercellular Communication | Chronic inflammation may play an etiologic role in endometrial cancer. | 19401534 |
| Inflammation | Altered Intercellular Communication | Laboratory investigations revealed systemic inflammation and lymphomonocytic pleocytosis of cerebrospinal fluid, supporting the diagnosis of Crohn's disease-associated vasculitis. | 19402574 |
| Inflammation, Ear Inflammation | Altered Intercellular Communication | Otitis media (OM) is an inflammation of the middle ear. | 19402800 |
| Inflammation, Uveitis | Altered Intercellular Communication | In uveitic eyes, active inflammation within 3 months before surgery increased the risk of CME when compared with eyes without inflammation (RR, 6.19; P = .04). | 19403110 |
| Inflammation, Thyroid carcinoma, Encapsulated Mass, Malignant Neoplasms | Altered Intercellular Communication | The authors suggest that these nonencapsulated lesions with no sign of inflammation may represent an early stage that may evolve to clinical cancers, contributing to the high incidence of clinically differentiated thyroid carcinomas observed in RN. | 19403545 |
| Inflammation, Cardiovascular Diseases | Altered Intercellular Communication | Both oxidative stress and inflammation are known to play roles in the pathogenesis of cardiovascular disease. | 19403985 |
| Enterocolitis, Crohn Disease, Specimen Type - Fistula | Altered Intercellular Communication | An 18-year-old male experienced a first episode of Crohn's disease with inflammation of the colon, stenosis of small intestine and a fistula of the anal sphincter. | 19404201 |
| Inflammation, Hemorrhage | Altered Intercellular Communication | Diagnostic work-up - gastroscopy and colonoscopy 2004 and 2006, magnetic resonance enteroclysis 2004 and 2006 and wireless capsule enteroscopy 2006 - revealed slight inflammation in the ileum but no bleeding source. | 19404201 |
| Inflammation, Thrombosis | Altered Intercellular Communication | Thrombin-activated factor 2 receptor (F2R) links thrombosis to inflammation modulating interleukin (IL)6 synthesis. | 19404549 |
| Inflammation, Inflammatory disorder, Atherosclerosis | Altered Intercellular Communication | Interleukin-8 is a strong mediator of inflammation and has been implicated in the biochemical pathways involved in a wide range of inflammatory diseases including atherosclerosis. | 19404719 |
| Refractory anemias, Inflammation | Altered Intercellular Communication | The modest clinical efficacy plus the transient suppression of biomarkers of inflammation observed in this study suggest that p38 MAPK inhibition may not provide meaningful, sustained suppression of the chronic inflammation seen in RA. | 19404957 |
| Lymphocyte count increased, Inflammation, Eosinophilic disorder, Edema, Nasal Polyps | Altered Intercellular Communication | Although many proinflammatory cytokines have been identified in nasal polyp tissue, the initial trigger that causes this inflammation characterized by edema, lymphocytosis, and eosinophilia, is still unknown. | 19405090 |
| vascular inflammations | Altered Intercellular Communication | Statins can inhibit cell proliferation and vascular inflammation, which might help prevent AAA progression. | 19406402 |
| Inflammation, Atherosclerosis, Cerebrovascular accident | Altered Intercellular Communication | Inflammation plays an important role in atherosclerosis and stroke. | 19407453 |
| Bacterial Infections, Venous Stroke | Altered Intercellular Communication | LPS stimulation of PBMCs, a condition mimicking bacterial infection, induces differential expression of a group of cell-cell signaling genes in patients with previous atherothrombotic stroke. | 19407453 |
| Inflammation | Altered Intercellular Communication | Under inflammatory conditions, neutrophil apoptosis is delayed due to survival-factor exposure, a mechanism that prevents the resolution of inflammation. | 19407828 |
| Inflammation | Altered Intercellular Communication | Under inflammatory conditions, neutrophil apoptosis is delayed due to survival-factor exposure, a mechanism that prevents the resolution of inflammation. | 19407828 |
| Inflammation, Intraepithelial Neoplasia | Altered Intercellular Communication | Loss of cell polarity, a histological feature of gastric epithelial dysplasia, may be difficult to ascertain, especially in the setting of inflammation or injury. | 19407852 |
| Inflammation, Parietal, Visceral Pain, Structure of phrenic nerve | Altered Intercellular Communication | Whereas laparotomy results mostly in parietal pain, patients after laparoscopic cholecystectomy complain more of visceral pain results from the stretching of intraabdominal cavity, peritoneal inflammation and phrenic nerve irritation caused by residual carbon dioxide in the peritoneal cavity. | 19408641 |
| Inflammation | Altered Intercellular Communication | Moderate-to-severe gingival inflammation (modified SBI) was observed in 67.3% of the subjects. | 19408821 |
| Inflammation, Restenosis | Altered Intercellular Communication | Other factors such as macrophage-induced inflammation and reactive oxygen species accumulation may also contribute to restenosis. | 19409002 |
| Inflammation, Respiration Disorders, Endothelial dysfunction | Altered Intercellular Communication | Candidate genes for respiratory disease associated with markers of inflammation and endothelial dysfunction in elderly men. | 19409562 |
| Inflammation, Endothelial dysfunction, Cyclophosphamide/Vincristine/Dacarbazine Regimen, Cardiovascular Diseases | Altered Intercellular Communication | Inflammation and endothelial dysfunction are important risk factors for cardiovascular disease (CVD). | 19409562 |
| ARCN1 gene, Inflammation, Chronic Obstructive Airway Disease, Endothelial dysfunction, Asthma | Altered Intercellular Communication | We hypothesized that candidate genes selected for a study of asthma and chronic obstructive pulmonary disorder (COPD) are associated with markers of systemic inflammation and endothelial dysfunction in an aging population. | 19409562 |
| ARCN1 gene, Inflammation, Cardiovascular Diseases, Endothelial dysfunction, Asthma | Altered Intercellular Communication | Our results suggest that genes thought to play a role in the pathogenesis of asthma and COPD may influence levels of serum markers of inflammation and endothelial dysfunction via novel SNP associations which have not previously been associated with cardiovascular disease. | 19409562 |
| Inflammation, Cardiovascular Diseases, Diabetes Mellitus | Altered Intercellular Communication | In patients with cardiovascular diseases several risk factors such as high blood pressure, diabetes, smoking and drinking habits, genetic disposition, and chronic inflammation must be considered. | 19410072 |
| Tracheitis, Subglottic stenosis | Altered Intercellular Communication | The study shows a successful symptomatic medical treatment of subglottic stenosis with resolution of tracheal inflammation and subglottic stenosis. | 19410129 |
| Inflammation, Endothelial dysfunction | Altered Intercellular Communication | There is an association between inflammation and endothelial dysfunction. | 19410250 |
| Inflammation, Endothelial dysfunction | Altered Intercellular Communication | Systemic inflammation may be, at least in part, a cause and predictor of progression of endothelial dysfunction. | 19410250 |
| Vasculitis, Atherosclerosis | Altered Intercellular Communication | Angiotensin II is a vasoactive peptide involved in vessel inflammation during atherosclerosis, and angiotensin II receptor inhibitors are effective in preventing atherosclerosis. | 19410957 |
| Humor, Vitreous inflammatory cells | Altered Intercellular Communication | Visual acuity, anterior chamber and vitreous inflammation, optical coherence tomography findings, serial electro-oculograms (EOGs), microperimetry (MP-1) testing, flow cytometric analysis of cells derived from the aqueous humor, and aqueous humor cytokine profiles were evaluated. | 19410956 |
| Respiratory Distress Syndrome, Adult, Inflammation, Disease | Altered Intercellular Communication | C-reactive protein (CRP) has been studied as a marker of systemic inflammation and outcome in a number of diseases, but little is known about its characteristics in ARDS. | 19411291 |
| Inflammation | Altered Intercellular Communication | These data appear to be contrary to the established view that CRP is solely a marker of systemic inflammation. | 19411291 |
| Malignant Neoplasms | Altered Intercellular Communication | Differentially expressed genes were identified associated with malignancy, survival as well as hormonal activity providing a resource of candidate genes for an exploration of possible drug targets and diagnostic and prognostic markers. | 19411298 |
| Inflammation, Chronic Obstructive Airway Disease | Altered Intercellular Communication | Defective efferocytosis in the airway may perpetuate inflammation in smokers with/without chronic obstructive pulmonary disease. | 19411612 |
| Inflammation, Diabetes Mellitus, Non-Insulin-Dependent | Altered Intercellular Communication | MATERIALS/SUBJECTS:We used lipopolysaccharide-activated cells from normal glucose tolerant (NGT) subjects and from Type 2 diabetes mellitus (T2DM) patients as T2DM is associated with chronic, low-grade inflammation, and measured immune mediator release with multiplex bead-based assays. | 19411809 |
| Diabetes Mellitus, Insulin-Dependent, Chronic inflammation, Myocarditis, CTCAE 5.0, MS gene | Altered Intercellular Communication | The latter are important murine pathogens that cause myocarditis, type 1 diabetes and chronic inflammation in the brains, mimicking multiple sclerosis. | 19412527 |
| Colon diverticulum anatomic structure | Altered Intercellular Communication | Chicken-bone perforation of a sigmoid colon diverticulum into the right groin and subsequent phlegmonous inflammation of the abdominal wall. | 19412753 |
| Perforation (observation) | Altered Intercellular Communication | We report an 82-year-old woman with perforation of a sigmoid diverticulum into the right groin with subsequent phlegmonous inflammation of the abdominal wall. | 19412753 |
| Inflammation | Altered Intercellular Communication | It is probably the result of acute inflammation in the subretinal space. | 19412871 |
| Inflammation | Altered Intercellular Communication | Interleukin-17A (IL-17A) and IL-17F play a role in tissue inflammation by inducing release of proinflammatory and neutrophil-mobilizing cytokines. | 19414056 |
| Inflammation, Atrophy of mucosa of stomach | Altered Intercellular Communication | In addition, IL-17A/-197A allele carriers had an increased risk of the development of gastric mucosal atrophy (OR, 1.68; 95% CI, 1.06-2.65; p = 0.026), and a positive relationship between the inflammation score and the number of -197A allele was observed (p = 0.022). | 19414056 |
| Communicable Diseases, Inflammation | Altered Intercellular Communication | The host is not able to clear the infection, leading to life-long chronic inflammation with continuous infiltration of lymphocytes and granulocytes. | 19414551 |
| Hernia of abdominal cavity, Pain Distress Question, Proteinuria, Toxic effect, Hypertension, CTCAE | Altered Intercellular Communication | Grade 3+ toxicities that occurred more often in the experimental arm versus control arm included hypertension (12% v 1.8%, respectively), wound complications (abdominal incisional hernia or infusion port dehiscence/inflammation; 1.7% v 0.3%, respectively), pain (11.1% v 6.3%, respectively), and proteinuria (2.7% v 0.8%, respectively). | 19414665 |
| Inflammation, Neoplasms, Neurosarcoidosis, Meningitis, Diabetes Mellitus, Vasculitis, CTCAE | Altered Intercellular Communication | Painful ophthalmoplegia is a rare pathologic condition caused by non-specific inflammation of the cavernous sinus, but other causes such as tumours, vasculitis, basal meningitis, neurosarcoidosis, diabetes can be responsible for the syndrome. | 19415444 |
| Gastritis | Altered Intercellular Communication | Heavy bacterial colonization (P = 0.008) and intense gastric inflammation (P < 0.0001) were associated significantly with severe clinical manifestations. | 19416374 |
| Inflammation, Depression, CTCAE | Altered Intercellular Communication | Therefore, our results imply that depression may lead to inflammation and that inflammation may be one of the mechanisms through which depression contributes to cardiovascular risk. | 19416750 |
| Gingivitis | Altered Intercellular Communication | We emphasize that severe gingival inflammation, although infrequent, may represent an alteration specific to DC and therefore should be considered as an additional sign of this syndrome. | 19419466 |
| Inflammation, Periodontitis, Vascular Diseases | Altered Intercellular Communication | Periodontitis is ubiquitous and associated with serological evidence of exposure to periodontal organisms, systemic inflammation and vascular disease. | 19419981 |
| Presenile dementia, Inflammation, Diabetes Mellitus, Cerebrovascular accident | Altered Intercellular Communication | Dementia is a major public health problem likely related to a complex interaction between genetics and diseases associated with systemic inflammation, including diabetes, smoking and stroke. | 19419981 |
| Central nervous system demyelination, Inflammation, Demyelination, Axonal loss | Altered Intercellular Communication | Tissue was stained immunohistochemically and examined to determine: (i) the number of surviving corticospinal tract axons; (ii) the extent of grey and white matter demyelination; (iii) the degree of inflammation inside and outside of lesions; and (iv) the relationship between demyelination and axonal loss. | 19420101 |
| Bacteremia, Inflammation, Communicable Diseases | Altered Intercellular Communication | This report serves as a reminder that, although occurring rarely, inflammation overlying a cephalohematoma in an infant with bacteremia can indicate focal infection that requires incision and drainage for resolution. | 19420180 |
| Pain Distress Question, Neurogenic Inflammation, Chronic pain, Complex Regional Pain Syndromes | Altered Intercellular Communication | One dominant etiological hypothesis is that major mechanisms for CRPS symptoms, which might be present during the course of CRPS, are trauma-related cytokine release, exaggerated neurogenic inflammation, sympathetically maintained pain, and cortical reorganization in response to chronic pain. | 19420958 |
| Benign prostatic hypertrophy | Altered Intercellular Communication | The histological diagnosis was benign prostatic hyperplasia (BPH) or chronic inflammation. | 19420972 |
| Inflammation, Atherosclerosis | Altered Intercellular Communication | Measures of inflammation, such as hs-CRP, and indices of atherosclerosis, such as CCS, are likely to provide distinct information regarding cardiovascular risk. | 19421644 |
| Degenerative polyarthritis, Arthritis, Arthritis, Infectious | Altered Intercellular Communication | Synovial fluid cf-DNA/NETs values from patients with septic arthritis (3,286 +/- 386 ng/ml, n = 9) were significantly increased compared to patients with noninfectious joint inflammation (1,040 +/- 208 ng/ml, n = 17) or osteoarthritis (278 +/- 34 ng/ml, n = 16, p < 0.01). | 19422041 |
| Inflammation, Atrial Fibrillation, Atrial Fibrillation by ECG Finding | Altered Intercellular Communication | Inflammation has been shown to have a direct role in the initiation, maintenance, and recurrence of atrial fibrillation (AF) although the underlying mechanisms are unknown. | 19422587 |
| Necrotizing granulomatous inflammation | Altered Intercellular Communication | Surprisingly, active cryptococcal infection with necrotizing granulomatous inflammation was demonstrated in the parathyroid, despite being on therapy. | 19422668 |
| Inflammation, Primary malignant neoplasm | Altered Intercellular Communication | One of the most current intriguing hypotheses on lung cancerogenesis envisages a role for inflammation as a possible trigger of both epithelial-mesenchymal transition and cancer development. | 19423183 |
| Inflammation, Carcinoma of lung | Altered Intercellular Communication | Cigarette smoke has been suggested to be the main factor underlying the inflammation of the airways described in lung cancer patients. | 19423183 |
| Inflammation, Carcinoma of lung | Altered Intercellular Communication | We support the hypothesis that cigarette smoke be strongly connected to the inflammation of the airways observed in lung cancer patients. | 19423183 |
| Noninfiltrating Intraductal Carcinoma | Altered Intercellular Communication | Our results support the theory that comedo-type DCIS may share hormonal and reproductive risk factors with IBC, whereas the etiology of non-comedo DCIS deserves further investigation. | 19423528 |
| Inflammation, Fibrosis Assessment | Altered Intercellular Communication | Intragraft FOXP3 protein or mRNA during acute renal allograft rejection correlates with inflammation, fibrosis, and poor renal outcome. | 19424039 |
| Acute inflammation, Aortitis Syndrome | Altered Intercellular Communication | The diagnosis of aortitis syndrome was made due to protracted postoperative inflammation. | 19425374 |
| Inflammation, Convulsive Seizures, Depression, CTCAE, Somatoform Disorder | Altered Intercellular Communication | They may have the character of the inflammation of the peripherial nerves, convulsive seizures or take the form of the depression or the psychoorganic syndrome. | 19425488 |
| Inflammation | Altered Intercellular Communication | Chronic airflow obstruction and markers of systemic inflammation: results from the BOLD study in Iceland. | 19427181 |
| ARCN1 gene, Inflammation | Altered Intercellular Communication | Elevated circulating levels of C-reactive protein (CRP) and interleukin-6 (IL-6), both markers of systemic inflammation, have been found in COPD. | 19427181 |
| Inflammation | Altered Intercellular Communication | This finding underscores the possible importance of systemic inflammation in irreversible airflow limitation. | 19427181 |
| Inflammation, Heart failure, Metabolic Syndrome X | Altered Intercellular Communication | The roles of metabolic syndrome and chronic subclinical inflammation in arterial stiffening and the development of heart failure remain to be elucidated. | 19427438 |
| Arterial Stiffness, Inflammation, Ventricular Dysfunction, Metabolic Syndrome X | Altered Intercellular Communication | Because adiponectin, hs-CRP, ba-PWV, and NT-pro-BNP may represent markers for metabolic syndrome, chronic subclinical inflammation, arterial stiffness, and ventricular dysfunction, respectively, our results suggest that adiponectin may directly modulate both arterial stiffening and ventricular dysfunction. | 19427438 |
| Inflammation, Hyperglycemic Hyperosmolar Nonketotic Coma | Altered Intercellular Communication | Hemichorea-hemiballismus associated with nonketotic hyperglycemia: a possible role of inflammation. | 19428031 |
| Inflammation, Chorea, AMT gene | Altered Intercellular Communication | These results suggested that inflammation within the central nervous system may participate in the pathogenesis of chorea and ballismus induced by NKH. | 19428031 |
| Inflammation, Bipolar Disorder | Altered Intercellular Communication | Converging lines of evidence support an association between systemic inflammation and depressive symptoms. | 19428978 |
| Refractory anemias, Rheumatoid Arthritis, Depression, CTCAE | Altered Intercellular Communication | Neuroimmune pathways may account for the high prevalence of depression in individuals with inflammatory conditions such as rheumatoid arthritis (RA). | 19428978 |
| Inflammation, Calcinosis | Altered Intercellular Communication | Serum levels of the calcification inhibitor fetuin-A are associated with the progression of AVC and MACE, independent of the renal function and inflammation. | 19429630 |
| Inflammation, Siderosis | Altered Intercellular Communication | The demonstration of CSF oligoclonal bands in the reported patient implies that inflammation might be involved in the pathogenesis of superficial siderosis. | 19430272 |
| Ischemia, Inflammation | Altered Intercellular Communication | We can speculate that the overexpression of VEGF induced by local ischemia and inflammation can make these patients more likely to have CNV. | 19430731 |
| Inflammation | Altered Intercellular Communication | 11C-choline or 18F-labelled choline derivatives for visualizing the synthesis of phospholipids, are promising markers of plaque inflammation with potential advantages over 18F-FDG. | 19430785 |
| Edema, prostatitis | Altered Intercellular Communication | This accounts for its ability to reduce edema in prostatic inflammation. | 19432231 |
| Inflammation, Polyp of urethra, Traumatic injury | Altered Intercellular Communication | Factors of a higher risk of acquired urethral polyps are secondary trauma of urethral mucosa in device investigations and manipulations as well as chronic inflammation. | 19432235 |
| Inflammation, Choline Dehydrogenase, Mitochondrial | Altered Intercellular Communication | We further demonstrate that the association of Hb, Hp, and Hx proteins with HDL positively correlates with inflammatory properties of HDL and systemic inflammation in CHD patients. | 19433579 |
| Inflammation | Altered Intercellular Communication | Motor involvement is probably due to the spreading of inflammation from the dorsal root ganglia to the ventral roots and may be more extensive than the affected dermatomes. | 19434442 |
| Corneal edema | Altered Intercellular Communication | The eye had mild corneal edema with anterior chamber inflammation. | 19435962 |
| Inflammation, Dental Plaque | Altered Intercellular Communication | This result suggests that inflammation simultaneously contributes to both plaque growth and plaque instability. | 19436122 |
| Inflammation, Carcinogenesis | Altered Intercellular Communication | Growing evidence points to a role for inflammation in prostate carcinogenesis. | 19436291 |
| Airway structure, Chronic Obstructive Airway Disease | Altered Intercellular Communication | Assessment of airway inflammation in the clinical course of acute exacerbations of chronic obstructive pulmonary disease (AECOPD) may advance our understanding of the pathogenesis and treatment. | 19436689 |
| Airway structure | Altered Intercellular Communication | To assess airway inflammation in patients during the course of AECOPD by serial analyses of their exhaled breath condensates (EBC). | 19436689 |
| ARCN1 gene, Inflammation | Altered Intercellular Communication | Change in inflammation in out-patient COPD patients from stable phase to a subsequent exacerbation. | 19436694 |
| ARCN1 gene | Altered Intercellular Communication | Inflammation increases during exacerbations of COPD, but only a few studies systematically assessed these changes. | 19436694 |
| Tumor necrosis, Inflammation, Bacterial Infections, Exacerbation | Altered Intercellular Communication | These exacerbations had significantly increased sputum total cell and neutrophil counts, leukotriene-B4, myeloperoxidase, interleukin-8 and interleukin-6, and tumor necrosis factor-alpha (TNF-alpha) levels, and were also associated with more systemic inflammation compared to exacerbations without a bacterial infection. | 19436694 |
| Inflammation, Bacterial Infections, Exacerbation | Altered Intercellular Communication | The increase in systemic inflammation during exacerbations seems to be limited to exacerbations caused by bacterial infections of the lower airways. | 19436694 |
| Inflammation, Erythema, Pyoderma Gangrenosum, Ulcer | Altered Intercellular Communication | In addition, there were ulcerative lesions surrounded by cutaneous inflammation and erythema on her extremities, indicative of pyoderma gangrenosum. | 19437575 |
| Inflammation, Sarcopenia | Altered Intercellular Communication | Inflammation in patients defined as frail by Fried's phenotypic definition may be related to sarcopenia. | 19438806 |
| Inflammation, Cardiovascular Diseases | Altered Intercellular Communication | C-reactive protein (CRP), a marker of inflammation, has been associated with cardiovascular disease. | 19438929 |
| Inflammation, Cardiovascular Diseases, Coronary heart disease | Altered Intercellular Communication | Given the high risk of cardiovascular disease in South Asians and the importance of inflammation in coronary heart disease we tested the hypothesis that circulating C-reactive protein (CRP) and interleukin 6 (IL-6) would be higher in healthy British born infants of South Asian origin than in infants of European origin in the first 2 years of life. | 19439300 |
| Inflammation | Altered Intercellular Communication | In our cohort, South Asian origin infants had significantly lower markers of inflammation compared with European infants. | 19439300 |
| Airway structure | Altered Intercellular Communication | Induced sputum analysis has been widely used to assay airway inflammation. | 19439918 |
| Inflammation, Uterine Fibroids, Granulomatous, Vasculitis, CTCAE, Endometrial Carcinoma | Altered Intercellular Communication | Nongranulomatous inflammation occurred in most patients with IGynV, while the predominant histologic pattern noted in SGynV was granulomatous.While vasculitis was the only lesion in 32% of the resected specimens, leiomyomas (18.4%) and endometrial carcinoma (8.3%) were the most frequent concomitant benign and malignant (nonvasculitic) lesions, respectively. | 19440120 |
| Inflammation, Bacterial Infections, Malignant Neoplasms | Altered Intercellular Communication | These findings, taken together, suggest a link between bacterial infection, inflammation and amyloid deposition of pro-inflammatory proteins S100A8/A9 in the prostate gland, such that a self-perpetuating cycle can be triggered and may increase the risk of malignancy in the ageing prostate. | 19440546 |
| Pancreatitis, Acute, Communicable Diseases, Inflammation | Altered Intercellular Communication | Triggering receptor expressed on myeloid cells-1 expression on monocytes is associated with inflammation but not with infection in acute pancreatitis. | 19442309 |
| Inflammation | Altered Intercellular Communication | In AP, local inflammation is followed first by the systemic inflammatory response syndrome and then by the compensatory anti-inflammatory response syndrome, which is defined by low human leukocyte antigen (HLA)-DR expression on monocytes, increased concentration of the anti-inflammatory cytokine IL-10, and decreased monocyte function. | 19442309 |
| Communicable Diseases, Inflammation | Altered Intercellular Communication | Increased TREM-1 expression was associated with the presence of inflammation but not infection in AP. | 19442309 |
| Inflammation, Spondylitis | Altered Intercellular Communication | Ankylosing spondylitis (AS) is characterized by inflammation of the entheses and paravertebral structures, leading in time to bone formation at those sites. | 19442629 |
| Inflammation, Prediabetes syndrome | Altered Intercellular Communication | Community-based population data indicates the significant alterations of insulin resistance, chronic inflammation and urine ACR in IFG combined IGT group among prediabetic population. | 19442860 |
| Inflammation, Prediabetes syndrome, Endothelial dysfunction | Altered Intercellular Communication | IR, chronic inflammation and endothelial dysfunction dose exist in prediabetic individuals, especially in IFG+IGT population. | 19442860 |
| Inflammation | Altered Intercellular Communication | Gutt's index and ACR might seem to be more sensitive than adiponectin and HOMA-IR index as IR and chronic inflammation maker in prediabetic population. | 19442860 |
| Inflammation | Altered Intercellular Communication | Inflammation plays a key role in the development of AMI. | 19442944 |
| Inflammation, Carotid Stenosis, Giant Cell Arteritis, Arteritis, Acute myocardial infarction, Takayasu Arteritis | Altered Intercellular Communication | CE-CMR of the vessel wall has been found useful for the characterization of inflammatory tissue signal changes in patients with carotid artery stenosis, giant cell arteritis, or Takayasu's arteritis; however, it has never been serially performed in the coronary artery wall in patients with acute and chronic myocardial infarction using a gadolinium-based contrast medium and compared with systemic markers of inflammation. | 19442944 |
| Inflammation, Edema | Altered Intercellular Communication | This technique may be useful for the characterization of transient coronary tissue signal changes, which may represent edema or inflammation during the post-infarction phase. | 19442944 |
| Inflammation, Hemoperitoneum | Altered Intercellular Communication | Pathologically it was possible that the local inflammation (epicarditis) due to the deposition of amyloid in the epicardium and perivascular tissue caused the bloody effusion. | 19443978 |
| Inflammation, Endothelial dysfunction | Altered Intercellular Communication | Markers of endothelial dysfunction and inflammation were also evaluated. | 19444092 |
| Inflammation, Immune-mediated | Altered Intercellular Communication | These findings demonstrate altered T-cell subsets in patients with immune-mediated disease, particularly at sites of inflammation. | 19444449 |
| Inflammation | Altered Intercellular Communication | It also plays a role in inflammation and oxidative stress. | 19446293 |
| Inflammation, Systolic dysfunction, Atherosclerosis | Altered Intercellular Communication | Left ventricular (LV) systolic dysfunction is common in patients with atherosclerosis, and both inflammation and oxidative stress have also been implicated in its development and progression. | 19446293 |
| Degenerative polyarthritis, Inflammation | Altered Intercellular Communication | Ultrasonographic evidence of inflammation is frequent in hands of patients with erosive osteoarthritis. | 19447214 |
| Nonalcoholic Steatohepatitis, Inflammation, Liver carcinoma, Fatty Liver, Non-alcoholic Fatty Liver Disease, Liver Cirrhosis, Fatty Liver Disease | Altered Intercellular Communication | Nonalcoholic steatohepatitis (NASH) represents a subset of nonalcoholic fatty liver disease manifested by hepatic fatty infiltration and inflammation which may progress to cirrhosis and its subsequent complications, to include hepatocellular carcinoma. | 19448566 |
| Refractory anemias, Inflammation, Arthritis | Altered Intercellular Communication | Infliximab therapy was started 3 years and 8 months after TKAs as a result of multiple arthritides showing high inflammation of RA. | 19449010 |
| Inflammation, Atherosclerosis, Refractory anemias, Rheumatoid Arthritis, atherosclerotic | Altered Intercellular Communication | Although inflammation has a defined role in the pathogenesis of atherosclerosis, the link between rheumatoid arthritis (RA) parameters of disease activity and atherosclerotic findings are not defined. | 19449480 |
| Inflammation, Atrial Fibrillation by ECG Finding | Altered Intercellular Communication | Recently, inflammation has been considered as a risk factor of postoperative atrial fibrillation (PAF). | 19450160 |
| Inflammation, Toxic effect | Altered Intercellular Communication | Recent data suggest that systemic inflammation results in reduced hepatic drug metabolism and increased toxicity from chemotherapy. | 19450285 |
| Inflammation, Albinism, Ulcer | Altered Intercellular Communication | Immunosuppression (KS), chronic ulcer, inflammation, albinism, and solar radiation were identified risk factors. | 19450404 |
| Inflammation, Septic Shock | Altered Intercellular Communication | Given the harmful effects of NO excess in septic shock, ADMA levels may be increased as a counter-system against inflammation and oxidative stress in this life-threatening disorder. | 19450686 |
| Inflammation, Osteonecrosis of Jaw, Necrosis | Altered Intercellular Communication | Three main histological patterns were identified in ONJ patients: 1 - Areas with active acute inflammation, characterized by predominance of soft tissues, inflammatory infiltrate, acellular necrotic debris, thin-walled and dilated blood vessel, intensely basophilic bone spiculae with scalloped borders showing prominent bone resorption. | 19450715 |
| Inflammation | Altered Intercellular Communication | Varying degrees of inflammation in the protein localization of TIMP-3 and TIMP-4 were found. | 19450793 |
| Inflammation | Altered Intercellular Communication | TIMP-4 immunoreactivity (IR) was weak in the endothelial cells, fibroblasts, epithelial basal and parabasal cells while the degree of inflammation differed as well. | 19450793 |
| X-linked inheritance, Inflammation, Doctor of Dental Medicine, Degenerative disorder, Muscular Dystrophy, Duchenne | Altered Intercellular Communication | Duchenne muscular dystrophy (DMD) is an X-linked, degenerative muscle disease that is exacerbated by secondary inflammation. | 19451692 |
| Inflammation, Fibrosis Assessment | Altered Intercellular Communication | These studies suggest that OPN may be a promising therapeutic target for reducing inflammation and fibrosis in individuals with DMD. | 19451692 |
| Disability, Inflammation, Rheumatism | Altered Intercellular Communication | Mud-bath treatment has a relevant therapeutic activity in reducing symptoms and disabilities in rheumatic diseases, as studies on inflammation process and clinical symptomatology have shown. | 19452099 |
| Primary malignant neoplasm, Neoplasms | Altered Intercellular Communication | Tumor markers and rectal cancer: support for an inflammation-related pathway. | 19452524 |
| Inflammation, Colorectal Carcinoma | Altered Intercellular Communication | Inflammation may be a key element in the etiology of colorectal cancer. | 19452524 |
| Inflammation, Primary malignant neoplasm | Altered Intercellular Communication | In our study, we examine associations between factors related to inflammation and specific rectal cancer mutations. | 19452524 |
| Neoplasms | Altered Intercellular Communication | These results suggest that inflammation-related factors may have unique associations with various rectal tumor markers. | 19452524 |
| Ulcer, Inflammation, Pain Distress Question | Altered Intercellular Communication | At follow-up gastroscopy, no ulcers, inflammation, break in the mucosa, or pain was noted. | 19453029 |
| Inflammation, Malignant Neoplasms | Altered Intercellular Communication | Symptoms of inflammation dominating in the clinical picture do not exclude the possibility of malignancy. | 19453090 |
| Inflammation, Diverticular Diseases, chronic diverticulitis | Altered Intercellular Communication | Patients with symptomatic diverticular disease exhibit increased neuropeptides in mucosal biopsies which may reflect resolved prior inflammation, as it parallels the changes seen in acute and chronic diverticulitis. | 19453515 |
| Degenerative polyarthritis, Inflammation | Altered Intercellular Communication | It is possible that this mechanism might contribute to induce tissue regeneration and down-regulation of inflammation in OA. | 19453649 |
| Tolosa-Hunt Syndrome, Inflammation, Methylated spirit | Altered Intercellular Communication | Tolosa-Hunt syndrome (THS) is a very rare, relapsing, and remitting painful ophthalmoplegia caused by nonspecific granulomatous inflammation in the cavernous sinus. | 19453827 |
| Granulomatous inflammation | Altered Intercellular Communication | Brain MRI showed granulomatous inflammation in both cavernous sinuses and thickening of the surrounding dura mater of the cranial base, suggesting the coexistence of focal hypertrophic cranial pachymeningitis. | 19453827 |
| Inflammation | Altered Intercellular Communication | There might be a positive regulatory loop between NF-kappaB and TNF-alpha, which may contribute to inflammation in OLP; NF-kappaB may also protect epithelial keratinocytes from excessive apoptosis. | 19453840 |
| Inflammation | Altered Intercellular Communication | Immunoregulatory cytokines are more important for suppression of inflammation in asymptomatic lesions and in this context the effect of TGF-beta is more potent and different from IL-10. | 19453841 |
| Hematuria, CTCAE, Malignant Neoplasms | Altered Intercellular Communication | Urethral amyloidosis is a rare, probably inflammatory condition usually presenting with hematuria and obstructive urinary symptoms, thus mimicking urethral malignancy. | 19453902 |
| Inflammation, Adult onset, Myositis, CTCAE 5.0, Myositis | Altered Intercellular Communication | Sporadic inclusion-body myositis (sIBM) is the most common disabling, adult-onset, inflammatory myopathy histologically characterized by intense inflammation and vacuolar degeneration. | 19454532 |
| Inflammation, Primary malignant neoplasm, Neoplasm Metastasis | Altered Intercellular Communication | Matrix metalloproteinase-2 (MMP-2) is a well-known mediator of cancer metastasis but is also thought to be involved in several aspects of cancer development, including cell growth and inflammation. | 19454611 |
| Pneumonitis | Altered Intercellular Communication | In addition, loss of CD27 on BAL CD4(+) T cells inversely correlates with markers of lung inflammation. | 19454729 |
| Orbital Pseudotumor | Altered Intercellular Communication | Unilateral orbital inflammation in a child after a jellyfish sting to the lower extremities. | 19454944 |
| Orbital Pseudotumor | Altered Intercellular Communication | After 5 asymptomatic weeks, she developed unilateral orbital inflammation that did not respond to systemic antibiotics, antihistamines, or steroids. | 19454944 |
| Inflammation, Atherosclerosis | Altered Intercellular Communication | There is increasing evidence that adventitial inflammation may participate in atherosclerosis development. | 19455698 |
| Inflammation, Chronic infectious disease | Altered Intercellular Communication | It is possible that inflammation and some chronic infections, such as those induced by C. pneumoniae, could have a marked influence on adventitial cell proliferation. | 19455698 |
| Inflammation, Malignant Neoplasms | Altered Intercellular Communication | The interleukin-6 (IL-6) pathway is one of the mechanisms that link inflammation and angiogenesis to malignancy. | 19457231 |
| Inflammation, Primary malignant neoplasm | Altered Intercellular Communication | Because the C-reactive protein (CRP) is a representative marker for inflammation, CRP has recently been associated with the progression of disease in many cancer types. | 19457231 |
| Autoimmune Diseases, Inflammation | Altered Intercellular Communication | Th17 cells are CD4+ cells that produce interleukin 17 (IL-17) and are potent inducers of tissue inflammation and autoimmunity. | 19457253 |
| Inflammation, Thrombosis, Atherosclerosis | Altered Intercellular Communication | Chronic inflammation has also been associated with atherosclerosis and thrombosis. | 19458634 |
| Fibrinoid necrotizing inflammation | Altered Intercellular Communication | Serum MCP-1 levels were significantly correlated with the disease activity scores of 28 joints combined with CRP (DAS28-CRP), indicating the role of MCP-1 in the pathogenesis of rheumatoid inflammation. | 19458908 |
| Inflammation, Diabetes Mellitus, Non-Insulin-Dependent | Altered Intercellular Communication | Glycaemic status in relation to oxidative stress and inflammation in well-controlled type 2 diabetes subjects. | 19459227 |
| Inflammation, Obesity, Abdominal | Altered Intercellular Communication | Furthermore, inflammation was more related to abdominal obesity than to glycaemic control. | 19459227 |
| ARCN1 gene, Inflammation | Altered Intercellular Communication | Relationships between inflammation severity and small intestinal absorption of fats, protein, carbohydrates in patients with moderate and severe COPD means loss of essential nutrients, primarily protein and fats. | 19459416 |
| Inflammation | Altered Intercellular Communication | Despite an associated increase in systemic inflammation, G-CSF treatment does not lead to acute impairment of brachial artery endothelial function in either healthy subjects or patients with MI. | 19460770 |
| Inflammation, Ischemia | Altered Intercellular Communication | No evidence of inflammation or ischaemia was observed during G-CSF mobilisation and PBSC collection. | 19460773 |
| Inflammation, Cardiovascular Diseases | Altered Intercellular Communication | Inflammation has been identified as a marker for cardiovascular disease. | 19461006 |
| Inflammation, Carcinoma of lung | Altered Intercellular Communication | Epidemiological evidence suggests a relationship between chronic inflammation and lung cancer. | 19461122 |
| Inflammation | Altered Intercellular Communication | Inflammation in the lung may be modulated by host genetic factors such as polymorphisms in inflammatory genes. | 19461122 |
| Gastrointestinal inflammation, Neoplasms | Altered Intercellular Communication | More recently, the dimeric isoform of M2-pyruvate kinase (tumor M2-PK) has been suggested as a marker of gastrointestinal inflammation. | 19462434 |
| Inflammation | Altered Intercellular Communication | Meningoencephalitis of this case was thought to be caused by RP-associated perivascular inflammation. | 19462815 |
| Inflammation, Swelling | Altered Intercellular Communication | Blood test showed severe inflammation and computed tomographic (CT) scan demonstrated swelling and irregular enhancement of the right kidney. | 19462829 |
| Inflammation, Platelet aggregation test result | Altered Intercellular Communication | Additionally, there were strong correlations between platelet aggregation and flow cytometric measurements (p < or = 0.04) and between specific inflammation markers (p < or = 0.02). | 19463513 |
| Inflammation, Dyslipidemias, Hypertension, CTCAE, Obesity | Altered Intercellular Communication | T2DM is associated with obesity, hypertension, dyslipidemia, hypothalamic pituitary adrenocortical (HPA) axis abnormalities and inflammation, all of which have been shown to negatively impact the brain. | 19463794 |
| Prostatic fluid, Inflammation, Benign prostatic hypertrophy | Altered Intercellular Communication | Evaluation of interleukin-8 in expressed prostatic secretion as a reliable biomarker of inflammation in benign prostatic hyperplasia. | 19464042 |
| Inflammation, Prostatic fluid, Elastosis perforans serpiginosa | Altered Intercellular Communication | To provide objective parameters of inflammation, this prospective study quantified the IL-8 in expressed prostatic secretion (EPS) from BPH patients with or without histologic inflammation. | 19464042 |
| Migraine Disorders, Neurogenic Inflammation | Altered Intercellular Communication | Calcitonin gene-related peptide (CGRP) is a potent vasodilator and supposed to be responsible for neurogenic inflammation involved in migraine. | 19464067 |
| Hepatitis, Inflammatory disorder | Altered Intercellular Communication | Its role in inflammatory diseases of other organs is controversial and poorly investigated regarding liver inflammation, although the organ is innervated by CGRP containing primary sensory nerve fibers. | 19464067 |
| Necrotizing granulomatous inflammation | Altered Intercellular Communication | FNB confirmed the results for malignant PVT in four of five patients, for benign granulomatous inflammation PVT in one of five patients in which CEUS showed early arterial enhancement of the PVT. | 19464131 |
| Necrotizing granulomatous inflammation, Intrahepatic bile duct | Altered Intercellular Communication | In one patient with intrahepatic bile duct stone, CEUS were positive for malignant PVT, whereas FNB was negative (benign granulomatous inflammation PVT); follow-up examination confirmed benign PVT. | 19464131 |
| Chronic inflammation, Thoracic esophagus, Malignant Neoplasms | Altered Intercellular Communication | D2-40 immunohistochemical staining for human lymphatic epithelium was performed at three sites in the cervical and thoracic esophagus in 16 donated cadavers without macroscopic malignancy or chronic inflammation. | 19464457 |
| Inflammation | Altered Intercellular Communication | To our knowledge, this is the first report of CK after LASIK that required surgical intervention for interface inflammation. | 19465304 |
| ARCN1 gene, Inflammation, Chronic Obstructive Airway Disease | Altered Intercellular Communication | Several studies suggest that inhaled and oral corticosteroids repress systemic inflammation in chronic obstructive pulmonary disease (COPD). | 19465442 |
| Inflammation, Familial Mediterranean Fever, Fever, CTCAE, Brucellosis | Altered Intercellular Communication | Familial Mediterranean fever (FMF) is hereditary episodic febrile syndrome characterized by acute attacks of fever and serosal inflammation, generally lasting 1-3 days and resolves spontaneously. | 19466424 |
| ARCN1 gene, Inflammation, Chronic Obstructive Airway Disease | Altered Intercellular Communication | The chronic systemic inflammation and oxidative stress are important features in chronic obstructive pulmonary disease (COPD). | 19466515 |
| Inflammation, atherosclerotic | Altered Intercellular Communication | Both local and systemic inflammation and oxidative stress negatively affect the atherosclerotic process. | 19466515 |
| ARCN1 gene, Inflammation | Altered Intercellular Communication | Metabolic alterations, systemic inflammation, and neurohormonal activation frequently occur in patients with COPD. | 19466515 |
| Degenerative polyarthritis, Inflammation | Altered Intercellular Communication | Nitric oxide (NO) is a major mediator of joint tissue inflammation and damage in osteoarthritis (OA) and mediates the nitration of tyrosine (Y*) residues in proteins. | 19467351 |
| Inflammation, Gastric Squamous Cell Carcinoma, Leukocytosis, Squamous cell carcinoma | Altered Intercellular Communication | This case suggests that gastric squamous cell carcinoma likely arises in the setting of long-standing, chronic inflammation, and like squamous cell carcinoma in other organ systems, may be associated with paraneoplastic leukocytosis. | 19467693 |
| Inflammation | Altered Intercellular Communication | Adiponectin, leptin, markers of inflammation, apolipoproteins (apo) AI and B, and lipoprotein-associated phospholipase A(2) (Lp-PLA(2)) were measured. | 19468010 |
| Fibrosis Assessment, Stiff Skin Syndrome | Altered Intercellular Communication | Stiff skin syndrome: evidence for an inflammation-independent fibrosis? | 19468049 |
| Inflammation, Fibrosis Assessment | Altered Intercellular Communication | The data suggest that fibrosis in SSS might be independent from inflammation. | 19468049 |
| Inflammation | Altered Intercellular Communication | Evaluation encompassed endosopic signs of inflammation, its spread, and severity. | 19469256 |
| Inflammation, Skin carcinoma | Altered Intercellular Communication | Dense inflammation can obscure nonmelanoma skin cancer (NMSC) on frozen sections, prompting removal of additional layers to ensure negative margins. | 19469800 |
| Inflammation | Altered Intercellular Communication | Our objective was to develop an effective ultrarapid CK frozen section immunostain to be used during MMS in cases of NMSC with dense or perineural inflammation. | 19469800 |
| Inflammation | Altered Intercellular Communication | It is hopeful that this technique may prevent recurrences after MMS and limit the number of Mohs layers required to obtain free margins when inflammation is abundant. | 19469800 |
| Inflammation, Data types - Address | Altered Intercellular Communication | The skin of AD patients is usually colonized by Staphylococcus aureus (S. aureus); its exotoxins may trigger or enhance the cutaneous inflammation. | 19469892 |
| Data types - Address, Dermatitis | Altered Intercellular Communication | Several mediators are related to the AD immune imbalance and interleukin-18 (IL-18), an inflammatory cytokine, may play a role in the atopic skin inflammation. | 19469892 |
| Data types - Address, Dermatitis | Altered Intercellular Communication | IL-18 secretion from AD upon stimulation was similar from controls, which may indicate a diverse mechanism of skin inflammation maintained by Staphylococcus aureus. | 19469892 |
| Immune System Diseases, Data types - Address, Dermatitis | Altered Intercellular Communication | On the other hand, augmented IL-18 secretion from AD sera and non-stimulated cell culture may enhance the immune dysfunction observed in AD, leading to constant skin inflammation. | 19469892 |
| Inflammation, FAM126A gene | Altered Intercellular Communication | Our study suggests that control of inflammation might be critical for improving treatment outcome in advanced HCC. | 19470923 |
| Steatohepatitis, Hepatic inflammation, Inflammation, Metabolic Syndrome X | Altered Intercellular Communication | Hepatic inflammation secondary to liver steatosis is a potential contributor to the low-grade inflammation associated with the metabolic syndrome. | 19472103 |
| Inflammation, prostatitis | Altered Intercellular Communication | The expression of ERbeta is reduced with increased scores on the inflammation of the prostate tissues in BPH patients, and the decreased ERbeta expression may be associated with the inflammatory stimulation of prostatitis. | 19472903 |
| Refractory anemias, Inflammation, Rheumatoid Arthritis, Atherosclerosis | Altered Intercellular Communication | Chronic systemic inflammation is of major importance in the development of atherosclerosis in rheumatoid arthritis (RA). | 19473561 |
| Inflammation, Inflammatory disorder, Rheumatism | Altered Intercellular Communication | Development of a simple and accurate technique for detecting active inflammation in the joints and other tissues of patients with inflammatory disorders is an unmet need in rheumatic diseases. | 19473565 |
| Refractory anemias, Degenerative polyarthritis, Arthropathy | Altered Intercellular Communication | In this open-label, cross-sectional study, a total of 40 patients with RA (26 with one or more swollen joints, 14 with clinically quiescent joint disease; 0/66 joint count) as well as 6 patients with osteoarthritis, 12 patients with other inflammatory conditions and 5 healthy subjects received 0.1 mg of EC20 labeled with 20-25mCi of technetium-99m. | 19473565 |
| Disease, Inflammation, Inflammatory disorder, Brucellosis | Altered Intercellular Communication | During the last decade, the increasing knowledge on the pathogenic mechanisms related to a number of diseases associated to mutations of genes associated to autoinflammatory diseases had a terrific impact on the understanding of pivotal mechanisms regulating the inflammatory response and therefore represents one of the major advance in the field of inflammation.The International Congress on Familiar Mediterranean Fever and Systemic Autoinflammatory Diseases brings together the experts in the field every two and a half years and represents a unique opportunity for an update on the recent progress in this growing field. | 19473583 |
| Tissue damage, Inflammation, Structure of posterior cerebral artery | Altered Intercellular Communication | Inflammation has been described as a risk factor for PCa and depends on the production of cytokines in response to tissue damage or the presence of stimuli that induces cellular stress. | 19474090 |
| Inflammation, Structure of posterior cerebral artery | Altered Intercellular Communication | Accumulating epidemiological and molecular evidence suggests that inflammation is an important component in the etiology of PCa. | 19475570 |
| Inflammation, Endothelial dysfunction | Altered Intercellular Communication | Furthermore, a high degree of adherence to MD has been found related to lower concentrations of inflammation, endothelial dysfunction and coagulation markers. | 19475839 |
| Inflammation, Nasal Polyps, MS4A2 wt Allele, Allergic | Altered Intercellular Communication | Clinical patterns, a history of atopy, environmental exposure, eosinophil-mediated inflammation, the presence of inflammatory mediators, and sensitization to some allergens indicate that nasal polyposis is associated with allergic phenomena. | 19476014 |
| Inflammation | Altered Intercellular Communication | Ageing of HIV+ patients, insufficient penetration of anti-viral drugs into the brain with continuous low-grade viral production and inflammation may play a role. | 19476058 |
| Inflammation, Calcification of coronary artery | Altered Intercellular Communication | Favorable cardiovascular risk factor profile is associated with reduced prevalence of coronary artery calcification and inflammation in asymptomatic nondiabetic white men. | 19476570 |
| Inflammation, Cyclophosphamide/Vincristine/Dacarbazine Regimen | Altered Intercellular Communication | However, the relationship of the absence of CVRFs with subclinical CVD and inflammation is not well described. | 19476570 |
| Inflammation, Atherosclerosis | Altered Intercellular Communication | Our study supports the notion that a favorable CVD profile is associated with less underlying atherosclerosis and inflammation and further highlights the importance of primary prevention of CVRFs. | 19476570 |
| Inflammation, Primary malignant neoplasm | Altered Intercellular Communication | Osteopontin (OPN) is an important mediator of inflammation and cancer progression. | 19476604 |
| Inflammation | Altered Intercellular Communication | Preliminary studies indicate that USPIO-enhanced MRI can identify macrophage infiltration in human carotid atheroma in vivo and hence may be a surrogate marker of plaque inflammation. | 19477353 |
| Fibrosis Assessment, Interstitial inflammation, Bronchiolitis Obliterans | Altered Intercellular Communication | In the chemotherapy group, patterns of interstitial involvement were variable interstitial inflammation and fibrosis associated with obliterative bronchiolitis [Roberts JR, Eustis C, Devore R, et al. | 19477548 |
| Inflammation, Iridocyclitis, Retinal thickening | Altered Intercellular Communication | To determine the frequency of retinal thickening (RT) in eyes with iridocyclitis and to examine the correlations among anterior chamber (AC) inflammation, RT, and visual acuity. | 19477710 |
| Inflammation | Altered Intercellular Communication | Fast peritoneal membrane transport status may be due to inflammation or increased peritoneal membrane surface area. | 19478100 |
| Inflammation, hepcidin | Altered Intercellular Communication | Furthermore, the elevated levels of hepcidin-25 and hepcidin-20 were not correlated with the serum levels of markers for inflammation, interleukin-6 and C-reactive protein, in the patients with AMI. | 19478464 |
| Airway structure, ARCN1 gene, Chronic Obstructive Airway Disease, neutrophilic | Altered Intercellular Communication | Airway inflammation in chronic obstructive pulmonary disease (COPD) is predominately neutrophilic, but some subjects demonstrate eosinophilic airway inflammation. | 19478474 |
| Appendicitis, CTCAE | Altered Intercellular Communication | Our criteria can improve sensitivity in comparison with conventional major criteria because our criteria enabled us to differentiate appendicitis without periappendiceal inflammation from a normal appendix. | 19478631 |
| Inflammation, Gall Bladder Diseases | Altered Intercellular Communication | Transient arterial enhancement in patients with suspected biliary disease is well correlated with clinical parameters suggestive of inflammation. | 19478633 |
| Crohn Disease | Altered Intercellular Communication | Crohn's disease (CD) is a chronic granulomatous inflammation of the intestine. | 19479064 |
| Inflammation | Altered Intercellular Communication | The presence of MAP reactive T cells with a Th1 or Th1/Th17 phenotype may suggest a possible role of mycobacteria in the inflammation seen in CD. | 19479064 |
| Inflammation, Necrosis, Lupus Erythematosus | Altered Intercellular Communication | Remnants of secondarily necrotic cells fuel inflammation in systemic lupus erythematosus. | 19479824 |
| Autoimmune Diseases, Inflammation, Lupus Erythematosus, Systemic | Altered Intercellular Communication | Autoantibody-mediated phagocytosis of SNEC is accompanied by secretion of inflammatory cytokines, fueling the inflammation that contributes to the perpetuation of autoimmunity in SLE. | 19479824 |
| Airway structure, ARCN1 gene | Altered Intercellular Communication | Airway inflammation in COPD can be measured using biomarkers such as induced sputum and Fe(NO). | 19480658 |
| ARCN1 gene, Inflammation | Altered Intercellular Communication | This study set out to explore the heterogeneity of COPD using biomarkers of airway and systemic inflammation and pulmonary function by principal components analysis (PCA). | 19480658 |
| Airway structure, Inflammation | Altered Intercellular Communication | Unrelated components of disease were identified, including neutrophilic airway inflammation which was associated with systemic inflammation, and sputum eosinophils which were related to increased Fe(NO). | 19480658 |
| Airway structure | Altered Intercellular Communication | We confirm dissociation between airway inflammation and lung function in this cohort of patients. | 19480658 |
| Inflammation, Sarcoidosis, Granulomatous | Altered Intercellular Communication | Activated T helper (Th)-1 pulmonary CD4+ cells and their mediators are essential for the inflammation and granulomatous process in sarcoidosis. | 19480659 |
| Inflammation, Asthma, Kit Ligand, human | Altered Intercellular Communication | Serum levels of SCF and its soluble receptor c-kit seem to be reflect asthma severity suggesting a role for these molecules in asthmatic inflammation. | 19480722 |
| Inflammation, Dental Plaque | Altered Intercellular Communication | Inflammation is important in plaque vulnerability but the role of atheroprotective mediators in unstable plaques is not defined. | 19481824 |
| vascular inflammations | Altered Intercellular Communication | The apolipoproteinA-I (apoA-I) component of HDL, and CD4+/CD25+ regulatory T cells (with their major transcription factor, Foxp3), have been implicated in the suppression of vascular inflammation. | 19481824 |
| Inflammation | Altered Intercellular Communication | These data suggest ineffective/insufficient protection against atherosclerosis-mediated inflammation by these "atheroprotective" moieties. | 19481824 |
| Inflammation | Altered Intercellular Communication | These findings support the fact that abnormal MRI findings in the spinal cord may be reflective of active inflammation in the early stages of rapidly progressive HAM. | 19481863 |
| Inflammation, Traumatic injury | Altered Intercellular Communication | In this study, the change of p38 MAPK signaling pathway in trauma patient with different severity and its clinical significance in trauma inflammation were investigated. | 19482318 |
| Airway structure, Pyoderma Gangrenosum | Altered Intercellular Communication | Although the etiology of pyoderma gangrenosum is poorly understood, this case suggests that a common pathogenesis may account for the simultaneous cutaneous and airway inflammation. | 19483173 |
| Inflammation, Traumatic injury | Altered Intercellular Communication | The presence of cervical fat seems to be unrelated to patient age, parity, parametrial adipose tissue, inflammation, or prior trauma. | 19483621 |
| Inflammation, Waldenstrom Macroglobulinemia, Chronic osteomyelitis, Necrosis | Altered Intercellular Communication | Initially, 13 of 66 (19.7%) cases were read by a surgical pathologist as chronic inflammation, with 6 having features suggestive of chronic osteomyelitis, including polyclonal plasma cells, necrosis, and lymphoplasmacytic infiltrate. | 19483668 |
| Inflammation, Chronic osteomyelitis | Altered Intercellular Communication | Six of 13 (46%), were read as containing fragmented bony spicules, fibrotic and fatty marrow, lymphoplasmacytic inflammation, and aggregates of mature, polyclonal plasma cells, suggesting the possibility of chronic osteomyelitis. | 19483668 |
| Hyperglycemia, Inflammation | Altered Intercellular Communication | Hyperglycemia is associated with greater prevalence of prefrail and frail status; BMI, inflammation, and comorbidities do not explain the association. | 19484839 |
| Impatent structure, Communicable Diseases, Hydrocephalus, Neoplasms | Altered Intercellular Communication | Causes of unilateral hydrocephalus resulting from an obstruction at the Monro foramen include foraminal atresia, tumors, gliosis, contralateral shunting, and infectious and inflammatory conditions. | 19485736 |
| allergic inflammation | Altered Intercellular Communication | The pulmonary artery supplies the distal parts of the lungs and likely represents a site of immunological reaction in allergic inflammation. | 19486035 |
| Asthma | Altered Intercellular Communication | The objective of this study was to describe the inflammatory cell phenotype of pulmonary artery adventitial inflammation in lung tissue from patients who died of asthma. | 19486035 |
| Neoplasms | Altered Intercellular Communication | MF classically presents as patches, plaques and tumours as originally described by Alibert and Bazin, but many other clinical presentations may occur, often mimicking other inflammatory conditions. | 19486059 |
| Inflammation | Altered Intercellular Communication | Decreased CD3+CD16+ natural killer-like T-cell percentage and zeta-chain expression accompany chronic inflammation in haemodialysis patients. | 19486472 |
| HD Term Type, Inflammation | Altered Intercellular Communication | All the evaluated markers of inflammation were increased in HD patients. | 19486472 |
| Inflammation | Altered Intercellular Communication | Measures towards alleviating chronic inflammation could partially restore NKL T-cell impairment. | 19486472 |
| Inflammation | Altered Intercellular Communication | Persistent depressive symptomatology and inflammation: to what extent do health behaviours and weight control mediate this relationship? | 19486658 |
| Inflammation, Bipolar Disorder | Altered Intercellular Communication | In summary, the association between depressive symptoms and low grade inflammation can be partly explained by behavioural risk factors. | 19486658 |
| Inflammation, Depression, CTCAE | Altered Intercellular Communication | The presence of persistent depression appears to be associated with the greatest risk of elevated inflammation. | 19486658 |
| Inflammation, Atherosclerosis | Altered Intercellular Communication | Inflammation plays an important role in the initiation and progression of atherosclerosis but the contribution of neutrophils to this process is unclear. | 19486978 |
| Tumor necrosis, Inflammatory disease of mucous membrane | Altered Intercellular Communication | Moreover, from both the pathogenetic and therapeutic point of view, new relevant information is highlighted regarding the possible role of tumour necrosis factor alpha (TNF-alpha) in mucosal inflammation. | 19487168 |
| Granuloma, Inflammation | Altered Intercellular Communication | Histology revealed well-formed granulomas and markedly diminished inflammation. | 19487479 |
| Respiratory Distress Syndrome, Adult, Inflammation | Altered Intercellular Communication | Lungs of patients with acute respiratory distress syndrome show diffuse inflammation in normally aerated regions: a [18F]-fluoro-2-deoxy-D-glucose PET/CT study. | 19487931 |
| Respiratory Distress Syndrome, Adult, Acute Lung Injury, Respiratory Distress Syndrome, Newborn | Altered Intercellular Communication | Neutrophilic inflammation plays a key role in the pathogenesis of acute respiratory distress syndrome (ARDS) and acute lung injury (ALI). | 19487931 |
| Epithelial hyperplasia, Inflammation | Altered Intercellular Communication | Histology shows mild epithelial hyperplasia, severe inflammation and vessel proliferation in the corion. | 19488571 |
| Inflammation, physiopathological | Altered Intercellular Communication | Morphological alterations occur in the corion as vessel proliferations, inflammation, and intracytoplasmatic alterations in fibroblasts suggesting cellular dysfunction and damage. | 19488571 |
| Proctitis, organic disease | Altered Intercellular Communication | In conclusion, fecal calprotectin was found to be strongly associated with colorectal inflammation indicating organic disease. | 19488608 |
| Inflammation, Oculovestibuloauditory syndrome, Vasculitis, CTCAE, Autoimmune Disorder, CTCAE | Altered Intercellular Communication | Cogan's syndrome is a rare autoimmune disorder characterized by systemic vasculitis as well as eye and ear inflammation. | 19488953 |
| Tissue damage, Inflammatory abnormality of the eye | Altered Intercellular Communication | In some BD patients, latent tissue damage caused by recurrent ocular inflammation is not reflected by visual acuity or ophthalmoscopic findings. | 19489762 |
| Skin Diseases, Vesiculobullous, Inflammation | Altered Intercellular Communication | However, the initial vesiculobullous stage of IP is characterized histopathologically by eosinophilic inflammation, which is expected to respond to corticosteroids. | 19489863 |
| Anguilla island, Asthma, Nasal Polyps, Asthma, Aspirin-Induced, Inflammatory disease of mucous membrane, Rhinitis | Altered Intercellular Communication | Aspirin-intolerant asthma (AIA) is a subtype of asthma induced by non-steroidal anti-inflammatory drugs and characterized by an aggressive mucosal inflammation of the lower airway (asthma) and the upper airways (rhinitis and nasal polyp). | 19489917 |
| Inflammatory, Inflammation, Malignant Neoplasms | Altered Intercellular Communication | Our case is unique for several reasons: inflammation was limited to the epicardium (very few cases have been described to date); the patient was asymptomatic, with no clinical or echocardiographic evidence of constriction (this represents a novel finding, explained in part by the more limited extent of inflammation, with no significant fibrotic component and no parietal pericardial involvement); and this is the first report of epicarditis occurring in association with a malignancy, which we hypothesize may represent an inflammatory paraneoplastic process. | 19490015 |
| Inflammation, Heart Valve Prosthesis | Altered Intercellular Communication | Lipid-mediated inflammation and degeneration of bioprosthetic heart valves. | 19490057 |
| Nasal inflammation | Altered Intercellular Communication | These patients clearly differed from typical forms, especially for the nasal inflammation. | 19490808 |
| Diabetes Mellitus, Non-Insulin-Dependent, Inflammation, Endothelial dysfunction, Homocysteinemia | Altered Intercellular Communication | Homocysteinemia may play an etiologic role in the pathogenesis of type 2 diabetes by promoting oxidative stress, systemic inflammation, and endothelial dysfunction. | 19491213 |
| Fibrosis Assessment, Interstitial inflammation | Altered Intercellular Communication | NSIP/P was subdivided into cellular NSIP and fibrosing NSIP according to the proportions of interstitial inflammation and fibrosis. | 19491520 |
| Inflammation, Corneal Endothelial Cell Loss | Altered Intercellular Communication | After 14 months changes in most markers of inflammation, endothelial damage, and glycemic control were more beneficial in the intervention group. | 19491687 |
| Poi serotype, Postoperative ileus, Gastrointestinal inflammation | Altered Intercellular Communication | Although postoperative ileus (POI) is considered multifactorial, intestinal inflammation resulting from manipulation-induced mast cell activation is recognized as an important pathophysiological mechanism. | 19491822 |
| Inflammation, Fibrosis Assessment | Altered Intercellular Communication | Significant histology was defined as stage > or = 2 fibrosis or stage 1 fibrosis plus grade > or = 2 inflammation using the Batts-Ludwig scoring system. | 19491836 |
| Inflammation, Prostate carcinoma, Disseminated Intravascular Coagulation, Thrombophilia | Altered Intercellular Communication | Collectively, our findings suggest that TF-specific PCA of plasma MPs contributes to intravascular coagulation activation in patients with early-stage prostate cancer and may represent a potential link between hypercoagulability, inflammation, and disease progression. | 19492160 |
| Degenerative polyarthritis, Inflammation | Altered Intercellular Communication | Almost all (95%) of the patients with osteoarthritis had no signs of inflammation at the time of screening. | 19494370 |
| Inflammation, Atheroma, Coronary heart disease | Altered Intercellular Communication | Gender gap, inflammation and acute coronary disease: are women resistant to atheroma growth? | 19494403 |
| Inflammation, Atheroma, Calcinosis | Altered Intercellular Communication | The severity of luminal stenosis and the frequency of adventitial inflammation, intimal calcification and atheromas were determined microscopically for each segment. | 19494403 |
| Delusions, CTCAE, "Alzheimers Disease", Psychotic symptom, Hallucinations | Altered Intercellular Communication | Although the etiology of psychotic symptoms (hallucinations and delusions) in Alzheimer's disease is still not known, alterations in serotonergic neurotransmission have been proposed. | 19494443 |
| Have Autoimmune or Inflammatory Condition | Altered Intercellular Communication | In contrast, recent evidence suggests that IL-17-producing Th17 cells play a crucial role in autoimmune inflammation. | 19494507 |
| Inflammation, diabetic | Altered Intercellular Communication | Our results showed that nonobese diabetic patients at low cardiovascular risk had similar levels of subclinical markers of inflammation and fibrinolysis as matched healthy controls. | 19494532 |
| Neoplasm Metastasis | Altered Intercellular Communication | The purpose of this study is to examine the association between inflammation-related genetic polymorphisms and lymph node metastasis. | 19495883 |
| Neoplasm Metastasis | Altered Intercellular Communication | We then assessed the association between inflammation-related genes and lymph node metastasis. | 19495883 |
| Airway structure, Atopy | Altered Intercellular Communication | However, the association between the severity of EIB and FE(NO) is present and FE(NO) significantly predictive of EIB only in atopic subjects, suggesting different interaction between bronchial responsiveness and airway inflammation in non-atopic wheeze. | 19496956 |
| Inflammation | Altered Intercellular Communication | Future studies will clarify whether the presence of peripheral inflammation plays a mechanistic role in CAD evolution. | 19497509 |
| Malnutrition, Infection | Altered Intercellular Communication | Inflammation markers and malnutrition as risk factors for infections and impaired health-related quality of life among older nursing home residents. | 19497548 |
| Inflammation, Malnutrition, Infection | Altered Intercellular Communication | To explore malnutrition and inflammation markers as risk factors for poor outcome such as infections and impaired health-related quality-of-life (HRQoL) among nursing home residents. | 19497548 |
| Inflammation, Infection | Altered Intercellular Communication | None of the other inflammation markers were associated with the number of infections or with HRQoL. | 19497548 |
| Inflammation, Coronary Arteriosclerosis, Metabolic Syndrome X | Altered Intercellular Communication | Chemerin is associated with markers of inflammation and components of the metabolic syndrome but does not predict coronary atherosclerosis. | 19497986 |
| Inflammation, Obesity, Atherosclerosis | Altered Intercellular Communication | Given the convergence of adipocyte and macrophage function, chemerin may provide an interesting link between obesity, inflammation and atherosclerosis in humans. | 19497986 |
| Inflammation, Metabolic Syndrome X, Plaque, Atherosclerotic | Altered Intercellular Communication | We sought to examine the relationship of i) chemerin and markers of inflammation, ii) chemerin and components of the metabolic syndrome, and iii) chemerin and coronary atherosclerotic plaque burden and morphology. | 19497986 |
| Inflammation, Metabolic Syndrome X | Altered Intercellular Communication | Chemerin is strongly associated with markers of inflammation and components of the metabolic syndrome. | 19497986 |
| Inflammation, Vascular Alterations, Radiation-Induced Cancer, Ischemia | Altered Intercellular Communication | Radiation-induced brain injury (RBI) is an insidious side-effect of radiotherapy mediated by vascular alterations, inflammation and ischaemia. | 19499176 |
| Inflammation, Hodgkin Disease | Altered Intercellular Communication | Analysis of 18F-FDG PET diffuse bone marrow uptake and splenic uptake in staging of Hodgkin's lymphoma: a reflection of disease infiltration or just inflammation? | 19499219 |
| Sepsis, Inflammation | Altered Intercellular Communication | Peri-appendicitis is the serosal inflammation of the appendix, which is generally caused by extra-appendicular sepsis. | 19499688 |
| Acute inflammation, Perforation (observation) | Altered Intercellular Communication | At laparotomy, a 0.5 cm perforation was observed, localised at the distal ileum and the appendix was oedematous and hyperaemic, consistent with acute inflammation. | 19499688 |
| Inflammation, Acute Kidney Insufficiency | Altered Intercellular Communication | The three postoperative factors and risk scores were ("three I's") 1) unplanned intensive care unit admission = 4.0; 2) systemic inflammation = 3; and 3) acute renal impairment = 2.5. | 19499858 |
| Inflammation, Primary malignant neoplasm | Altered Intercellular Communication | The nuclear factor-kappaB (NF-kappaB) family is a set of transcription factors with key roles in the induction of the inflammatory response and may be the link between inflammation and cancer development. | 19500386 |
| AURKAIP1 gene, Inflammation, Autoimmune Pancreatitis | Altered Intercellular Communication | Autoimmune pancreatitis (AIP) is characterized by lymphoplasmocytic inflammation, high serum IgG4 concentrations, and a favorable response to corticosteroid treatment. | 19500628 |
| Inflammation | Altered Intercellular Communication | Additionally, G-CSF reduced systemic inflammation indicated by suppression of the production or activity of major pro-inflammatory cytokines in plasma. | 19500657 |
| Neoplasms, Optic Nerve Glioma, Neoplasms, Vascular Tissue, Orbital Pseudotumor, Adult Non-Hodgkin Lymphoma | Altered Intercellular Communication | Median uptake ratios of other tumors were vascular anomalies/vascular tumors, 1.2 (range, 0.5-3.3); non-Hodgkin lymphomas, 2.9 (range, 0.9-4.2); optic nerve gliomas, 1.5 (range, 0.2-3.3); and idiopathic orbital inflammation, 1.6 (range, 1.4-1.9). | 19500849 |
| Inflammation, Fibrosis Assessment, Pancreatitis | Altered Intercellular Communication | High Ras activity mimicking levels in PDAC led to acinar cell senescence and generated inflammation and fibrosis resembling the histologic features of chronic pancreatitis. | 19501586 |
| Autoimmune Diseases, Inflammation | Altered Intercellular Communication | Every imbalance in the accumulation of senescent cells between the immune system and the potential target organs can initiate a chronic inflammation or autoimmunity. | 19501986 |
| ARCN1 gene, Communicable Diseases, Chronic Obstructive Airway Disease | Altered Intercellular Communication | Latent adenoviral infection may amplify cigarette smoke-induced lung inflammation and therefore play an important role in the development of chronic obstructive pulmonary disease (COPD). | 19502044 |
| Osteitis, Fracture | Altered Intercellular Communication | In the group treated by open reposition and plate fixation, we found the following complications that might impede bone union: plate fracture, technical errors, screw loosening, bone inflammation, and other complications. | 19502670 |
| Inflammation, Werner Syndrome | Altered Intercellular Communication | The Werner syndrome protein affects the expression of genes involved in adipogenesis and inflammation in addition to cell cycle and DNA damage responses. | 19502800 |
| Crohn Disease, Inflammation | Altered Intercellular Communication | Long-term outcomes included acute pouchitis (antibiotic responsive), chronic pouchitis (antibiotic dependent or refractory), or de novo Crohn's disease (small inflammation above the pouch inlet or pouch fistula). | 19502850 |
| Ileitis | Altered Intercellular Communication | Inflammation proximal to the pouch, prepouch ileitis (PPI) has recently been described. | 19502851 |
| Inflammation | Altered Intercellular Communication | All of the patients had concurrent pouch inflammation, and in this group the incidence was 13 percent. | 19502851 |
| Inflammation, Ulcerative Colitis | Altered Intercellular Communication | The incidence of PPI in patients with ulcerative colitis/indeterminate colitis is 5.7 percent, and it occurs in 13 percent of patients with pouch inflammation. | 19502851 |
| Inflammation | Altered Intercellular Communication | All of the patients had associated pouch inflammation; however, not all of the patients were symptomatic. | 19502851 |
| Inflammation, Mandibular Condyle, Fibrosis Assessment, Structure of mandibular nerve, Sinusitis | Altered Intercellular Communication | Nineteen patients (54%) had abnormalities comprising radiotherapy-induced masticator muscle fibrosis (n = 19), denervation atrophy of the masticator muscles secondary to mandibular nerve damage (n = 1), mandibular ramus signal abnormalities (n = 5), mandibular condyle sclerosis with or without capsular thickening (n = 5), perimasticator fibrosis extending into the masticator space (n = 3) and inflammation secondary to severe sinusitis extending into the masticator space (n = 2). | 19504110 |
| Inflammation, Prostate carcinoma | Altered Intercellular Communication | The purpose of this study was to investigate two markers of gut inflammation during and after irradiation for prostate cancer to evaluate a correlation between acute and chronic proctitis. | 19504404 |
| Inflammation, Ulcerative Colitis | Altered Intercellular Communication | The findings of magnifying colonoscopy in patients with quiescent UC is useful for predicting relapse and is associated with histological grade of inflammation. | 19504617 |
| Respiratory Distress Syndrome, Adult, Inflammation, Respiratory Distress Syndrome, Newborn, Edema | Altered Intercellular Communication | Acute respiratory distress syndrome (ARDS) is characterized by diffuse inflammation in the lung and resultant permeability edema. | 19506468 |
| Inflammation, Cerebrovascular accident | Altered Intercellular Communication | The role of DCs (dendritic cells) as potent mediators of inflammation has not been sufficiently investigated in stroke. | 19508233 |
| Gingivitis, Calculi | Altered Intercellular Communication | The Community Periodontal Index (CPI) was used to report the occurrence of probing pocket depth, calculus, and gingival inflammation. | 19508245 |
| Vasculitis, Leukocytoclastic, Cutaneous, Inflammation | Altered Intercellular Communication | Leucocytoclastic vasculitis (LV) is characterized by necrotizing inflammation around small blood vessels, composed mainly of neutrophils and their debris. | 19508466 |
| Diabetes Mellitus, Non-Insulin-Dependent, Inflammation, Complications of Diabetes Mellitus | Altered Intercellular Communication | OBJECTIVE Subclinical inflammation is an important risk factor for type 2 diabetes and diabetes complications. | 19509015 |
| Inflammation, Diabetic Foot | Altered Intercellular Communication | However, data on the association between inflammation and acute diabetic foot syndrome are scarce. | 19509015 |
| Communicable Diseases, Inflammation, Ulcer | Altered Intercellular Communication | In multivariate models, size of ulcer according to the University of Texas classification but not the grade of infection was independently associated with three markers of subclinical inflammation (CRP, IL-6, and fibrinogen). | 19509015 |
| Adrenal Gland Hyperfunction, Inflammation | Altered Intercellular Communication | Despite long-term cure, patients who have suffered CS exhibit persistent accumulation of central fat, as in active hypercortisolemia, with the consequent unfavorable adipokine profile, leading to a state of low-grade inflammation. | 19509101 |
| Inflammation, Corneal Ulcer, Epithelial | Altered Intercellular Communication | Signs were redness (100%), epithelial defects (98.3%), superficial corneal ulcer (95.1%), anterior chamber inflammation (91.8%), and satellite infiltrates (75.4%). | 19512910 |
| Inflammation, Abnormality of the vasculature, Articulation Disorders | Altered Intercellular Communication | These results demonstrated that, in the tongue of chagasic patients, a microvascular abnormality and immunological impairment occurs, probably due to chronic inflammation evoked by T. cruzi antigens. | 19513749 |
| Inflammation, Electrocardiogram: myocardial infarction (finding) | Altered Intercellular Communication | [Acute inflammation phase reactants and interleukin-8 in myocardial infarction]. | 19514335 |
| Inflammation, Lung diseases | Altered Intercellular Communication | There was probably specific inflammation around bronchioles, and the inflammation might have spread to the alveolar region in such cases with severe pulmonary function disorder. | 19514496 |
| Abscess of orbit, Traumatic injury | Altered Intercellular Communication | The third case, a 69-year-old male with a right orbit abscess following a trauma with a tree branch had a persistent right orbit inflammation lasting 4 months despite two drainage surgeries and an extraction of an orbital organic foreign body. | 19515307 |
| Diabetes Mellitus, Metabolic Syndrome X, Obesity | Altered Intercellular Communication | Besides its well appreciated role in diabetes, obesity, and metabolic syndrome, insulin resistance (IR) is associated with smoking, use of hormonal contraceptives, androgens, glucocorticoids, beta-adrenergic blockers, thiazide diuretics, intake of food with high glycaemic index, and reduced physical activity. | 19515499 |
| Inflammation, Blood Clot | Altered Intercellular Communication | Here we investigated the relationship between MCs and inflammation, neovascularization, and the presence of intraluminal thrombus in human AAA. | 19515525 |
| Inflammation, Hypertension, CTCAE, Cardiovascular Diseases | Altered Intercellular Communication | Because inflammation is known to be related with several cardiovascular diseases, we sought to determine whether C-reactive protein (CRP) might precede the onset of hypertension. | 19516173 |
| Presenile dementia, Impaired cognition | Altered Intercellular Communication | However, besides altered acetylcholine transmission, other neurotransmitter systems are involved in cognitive dysfunction leading to dementia. | 19516251 |
| Fibrosis, Liver, Inflammation | Altered Intercellular Communication | Acquisition of HCV during this time could have further skewed this response resulting in massive hepatocyte destruction, inflammation, and subsequent liver fibrosis. | 19519227 |
| Chronicity, Communicable Diseases, Inflammation | Altered Intercellular Communication | Bacterial infection impairs the healing process, promoting the chronicity of inflammation and wounds. | 19519855 |
| Inflammation, Asbestos-Related Lung Disorder, Pleural Diseases, Asbestosis | Altered Intercellular Communication | In asbestos-related disorders, markers of inflammation and oxidative stress are significantly elevated in subjects with asbestosis compared with healthy individuals but not in pleural diseases. | 19520561 |
| Inflammation | Altered Intercellular Communication | High-sensitivity C-reactive protein (hs-CRP) is a sensitive systemic marker of inflammation, and increased levels of hs-CRP are associated with inflammatory reactions. | 19521085 |
| Chronic liver disease, Prostatic Neoplasms | Altered Intercellular Communication | We excluded patients receiving hormonal ablation for prostatic neoplasm and patients with chronic liver or renal disease and patients receiving corticosteroids. | 19521700 |
| Inflammation | Altered Intercellular Communication | In particular, in 23 out of 28 (82%) patients with positive H pylori antibodies, a likely cause of IDA was found because of the active inflammation involving the gastric body. | 19522025 |
| Inflammation, Hemorrhage, Intestinal Obstruction | Altered Intercellular Communication | It is usually asymptomatic but approximately 4% are symptomatic with complications such as bleeding, intestinal obstruction, and inflammation. | 19522035 |
| ARCN1 gene, Inflammation, Chronic Obstructive Airway Disease | Altered Intercellular Communication | Chronic obstructive lung disease (COPD) is characterised by partially reversible usually progressive airflow limitation caused by inflammation and remodelling. | 19522160 |
| Inflammation, Dermatitis, Granuloma | Altered Intercellular Communication | The sample taken from the inflammation on the chest wall was analyzed with PCR method which resulted positive for Acid Fast Bacilli (AFB), tissue biopsy showed dermatitis with granulomata and sputum was positive for AFB. | 19522164 |
| Labia Majora Carcinoma, Inflammation | Altered Intercellular Communication | We present the case of a 44-year-old woman with eruptive syringoma of the labia majora and prominent lymphocytic inflammation in the acrosyringium. | 19522848 |
| Inflammation, Acute Coronary Syndrome, Systolic dysfunction | Altered Intercellular Communication | Comparison of the long-term prognostic value of cystatin C to other indicators of renal function, markers of inflammation and systolic dysfunction among patients with acute coronary syndrome. | 19523634 |
| Renal Insufficiency, Inflammation, Systolic dysfunction, GDC AJCC Clinical Stage Terminology | Altered Intercellular Communication | We compared the long-term prognostic efficacy of Cys-C with other markers of renal dysfunction, inflammation and systolic dysfunction in patients with ACS. | 19523634 |
| Inflammation, Platelet aggregation | Altered Intercellular Communication | Ancillary effects include increased platelet aggregability, increased sympathic activation, oxidative stress, vascular endothelial dysfunction, inflammation, and metabolic dysregulation. | 19523714 |
| Fever, CTCAE | Altered Intercellular Communication | Inflammation of unknown origin versus fever of unknown origin: two of a kind. | 19524186 |
| Inflammation, Crohn Disease | Altered Intercellular Communication | Quantitative analysis of dynamic contrast enhanced MRI for assessment of bowel inflammation in Crohn's disease pilot study. | 19524458 |
| Inflammation | Altered Intercellular Communication | Receiver-operating characteristic analysis was performed to compare the diagnostic accuracy of the parameters in the task of distinguishing normal tissue from inflammation. | 19524458 |
| Inflammation, Crohn Disease | Altered Intercellular Communication | These preliminary results demonstrate that the quantitative analysis of DCE-MRI data is possible for the assessment of bowel inflammation in patients with Crohn's disease. | 19524458 |
| amyloid-beta binding, Inflammation | Altered Intercellular Communication | Simvastatin improves cerebrovascular function and counters soluble amyloid-beta, inflammation and oxidative stress in aged APP mice. | 19524673 |
| germinal vesicle, Graafian Follicle | Altered Intercellular Communication | The fact that germinal vesicle-stage oocytes were present in our patient's medium despite hormonal down-regulation demonstrates that GnRH agonist does not completely inhibit antral follicle development. | 19524895 |
| prostatitis | Altered Intercellular Communication | In asymptomatic men with mild increases of prostate specific antigen histological evidence of prostatic inflammation is common. | 19524953 |
| prostatitis | Altered Intercellular Communication | Our data suggest that 10 leukocytes per high power field in post-prostatic massage urine, the usually applied cutoff, may be too high for the definition of prostatic inflammation. | 19524953 |
| Inflammation, Demyelination, Multiple Sclerosis, Nerve Degeneration | Altered Intercellular Communication | Demyelination, inflammation, and neurodegeneration in multiple sclerosis deep gray matter. | 19525897 |
| Inflammation, White matter lesions | Altered Intercellular Communication | Inflammation in DGM lesions is intermediate between the destructive inflammation of white matter lesions and the minimal inflammation of cortical lesions. | 19525897 |
| Refractory anemias, Arthritis | Altered Intercellular Communication | FDG uptakes in joint lesions with MESC were much higher than those reported in typical lesions of RA, suggesting that marked joint inflammation is implicated in the development of MESC. | 19526305 |
| Inflammation, Traumatic injury | Altered Intercellular Communication | Ischaemia/reperfusion induces systemic inflammation and oxidative stress and thereby remote organ injury in the kidney. | 19526394 |
| Inflammation, Acute Coronary Syndrome, Dental Plaque, GDC AJCC Clinical Stage Terminology | Altered Intercellular Communication | Inflammation caused by activated macrophages and T lymphocytes may trigger plaque rapture in acute coronary syndrome (ACS). | 19527302 |
| Inflammation, Fibrosis Assessment | Altered Intercellular Communication | Perifollicular inflammation was almost a constant feature in early cases and showed a significant inverse correlation with perifollicular fibrosis (P = 0.048), which was more marked with thickening of the follicular sheath in advanced cases. | 19527330 |
| Neoplasms | Altered Intercellular Communication | These tumors are mainly benign and show typical luteinization associated with the hormonal milieu in pregnancy. | 19527401 |
| Inflammation, Ulcerative Colitis | Altered Intercellular Communication | We evaluated: (i) whether fecal supernatants from patients with ulcerative colitis (UC) trigger alterations of colonic paracellular permeability and inflammation, and (ii) the roles of cathepsin G (Cat-G), a neutrophil serine protease, and its selective receptor, PAR(4), in these processes. | 19528350 |
| Inflammation, Familial Mediterranean Fever | Altered Intercellular Communication | The precise pathologic mechanism is still to be definitively elucidated; however a new macromolecular complex, called inflammasome, seems to play a major role in the control of inflammation and it might be involved in the pathogenesis of FMF. | 19530512 |
| Necrotizing granulomatous inflammation, Muscle Rigidity | Altered Intercellular Communication | The first case had chronic granulomatous inflammation induced by the PDMS and the second a periprothetic fibrotic reaction causing cordal rigidity. | 19530528 |
| Inflammation | Altered Intercellular Communication | In case of chronic inflammation, an endoscopic removal is indicated. | 19530528 |
| Inflammation, Chronic heart failure, Congestive heart failure | Altered Intercellular Communication | Inflammation is implicated in chronic heart failure (CHF). | 19531154 |
| vascular inflammations, Congestive heart failure | Altered Intercellular Communication | This PPARalpha activator may have the potential to ameliorate vascular inflammation in patients with CHF. | 19531154 |
| Inflammation, Chemical injury | Altered Intercellular Communication | Ischemic injury and inflammation resulting from inadequate resuscitation might influence organ yield for transplantation. | 19531941 |
| Nonulcer dyspepsia, Dysautonomia, Familial, Inflammation | Altered Intercellular Communication | Although inflammatory changes in the gastric mucosa are commonly observed in Japanese patients with functional dyspepsia (FD), detailed data regarding the relationship between the genetic regulatory factors of inflammation and FD are not available. | 19531958 |
| Inflammation, Helicobacter Pylori-Related Carcinoma | Altered Intercellular Communication | Superoxide has been implicated in the pathogenesis of Helicobacter pylori-related diseases through inflammation. | 19531958 |
| Congenital neutropenia, Amyloidosis | Altered Intercellular Communication | We report about a patient with congenital neutropenia, AA amyloidosis and chronic intestinal bowel inflammation due to amyloid deposition in the bowel. | 19533073 |
| Sepsis, Inflammation | Altered Intercellular Communication | High-mobility group box 1 (HMGB1) is a late mediator of the systemic inflammation associated with sepsis. | 19533845 |
| Inflammation, Hemorrhage, Meckel Diverticulum, Intestinal Obstruction | Altered Intercellular Communication | Complications like intestinal obstruction, bleeding and inflammation of Meckel's diverticulum occur in 4% of patients. | 19534380 |
| Inflammation, Atheroma, Cardiovascular Diseases | Altered Intercellular Communication | Elevated blood levels in cardiovascular disease and local deposition in atheroma implies a role of SAA as a mediator rather than just a marker of inflammation. | 19535079 |
| Inflammation, Chronic Kidney Diseases | Altered Intercellular Communication | Outcome predictability of biomarkers of protein-energy wasting and inflammation in moderate and advanced chronic kidney disease. | 19535427 |
| Inflammation, Chronic Kidney Diseases | Altered Intercellular Communication | Markers of protein-energy wasting (PEW) and inflammation are common in chronic kidney disease (CKD) and are among the strongest predictors of mortality in dialysis patients. | 19535427 |
| Inflammation | Altered Intercellular Communication | We hypothesized that markers of PEW and inflammation show similar associations in patients with non-dialysis-dependent CKD (NDD-CKD). | 19535427 |
| Hypertension, CTCAE, Myelolipoma of adrenal gland, Neoplasms, Obesity | Altered Intercellular Communication | Adrenal myelolipoma is an uncommon tumour of the adrenal gland, usually unilateral, frequently associated with hypertension and obesity, with a benign biological behaviour and without hormonal activity, first described in 1905. | 19536999 |
| Inflammation, Heat-Shock Response | Altered Intercellular Communication | Fasting blood plasma was analysed for glucose, lipids, markers systemic inflammation, cytokines and antibodies against heat shock proteins (Hsp). | 19538326 |
| Inflammation, Impaired cognition | Altered Intercellular Communication | Chronic subclinical inflammation may elevate the risk of cognitive impairment. | 19538327 |
| Inflammation, Periodontitis, Tooth Loss | Altered Intercellular Communication | Periodontitis is associated with subclinical inflammation and accounts in part for tooth loss. | 19538327 |
| Arterial Stiffness, Inflammation, Acute Kidney Injury, CTCAE | Altered Intercellular Communication | Assessment of arterial stiffness, oxidative stress and inflammation in acute kidney injury. | 19538714 |
| Arterial Stiffness, Inflammation, Chronic Kidney Diseases | Altered Intercellular Communication | It is well know that arterial stiffness, oxidative stress and inflammation are features of chronic kidney disease. | 19538714 |
| Inflammation, Endothelial dysfunction, Vascular calcification, Atherosclerosis | Altered Intercellular Communication | The arterial changes have a multitude of potential interconnected causes including endothelial dysfunction, oxidative stress, inflammation, atherosclerosis and vascular calcification. | 19538714 |
| Inflammation, Hematemesis | Altered Intercellular Communication | Four patients presented with sudden massive hematemesis whereas 2 patients were readmitted for new-onset fever and elevated markers of inflammation that preceded hematemesis. | 19539264 |
| Inflammation, Pustulosis of Palms and Soles, Acne, Synovitis, Osteitis, Sapho, Hyperostosis | Altered Intercellular Communication | Synovitis, acne, pustulosis, hyperostosis, and osteitis (SAPHO) syndrome is a clinically heterogeneous entity, encompassing a variety of debilitating conditions that have in common inflammation of the skeletal system and skin. | 19539848 |
| ARCN1 gene, Inflammation | Altered Intercellular Communication | Currently, limited data are available about determining factors of systemic inflammation in COPD, in particular C-reactive protein (CRP). | 19540024 |
| ARCN1 gene, Inflammation | Altered Intercellular Communication | These findings are suggestive for an adipocyte-induced systemic inflammation in COPD. | 19540024 |
| Sepsis, Inflammation, Systemic Inflammatory Response Syndrome | Altered Intercellular Communication | The combined determination of MIF and PCT might, therefore, be useful to discriminate between post-burn inflammation and systemic inflammatory response syndrome (SIRS) or sepsis with lethal outcome. | 19540674 |
| Hematoma, Pseudoaneurysm | Altered Intercellular Communication | Five malignant and 14 benign histologies (including 6 types with inflammation-related, hematoma or pseudoaneurysm) occurred that had more than 10 subjects with each histology. | 19541566 |
| Inflammation, hepcidin | Altered Intercellular Communication | Serum hepcidin-25 is increased in hemodialysis patients, regulated by iron stores and inflammation, and relatively reduced in subjects carrying frequent HFE mutations. | 19541813 |
| Inflammation, Damage, Demyelination | Altered Intercellular Communication | Multiple sclerosis is a disease that is characterized by inflammation, demyelination, and axonal damage; it ultimately forms gliotic scars and lesions that severely compromise the function of the central nervous system. | 19541935 |
| palladium, Inflammation | Altered Intercellular Communication | These observations suggest that the alteration in PG components following PD therapy and severe inflammation contribute to fibrous thickening of the peritoneum. | 19542195 |
| Airway structure | Altered Intercellular Communication | DAC patients who underwent HRCT scanning compared with those who did not were older, had longer disease duration, had poorer lung function, were receiving higher doses of corticosteroids, and had increased neutrophilic airway inflammation. | 19542254 |
| ARCN1 gene, Inflammation, Metabolic Syndrome X, Bronchitis | Altered Intercellular Communication | The metabolic syndrome in patients with chronic bronchitis and COPD: frequency and associated consequences for systemic inflammation and physical inactivity. | 19542257 |
| ARCN1 gene, Inflammation | Altered Intercellular Communication | Systemic inflammation and physical inactivity are relevant extrapulmonary markers of morbidity and mortality in patients with COPD. | 19542257 |
| ARCN1 gene, Inflammation, Metabolic Syndrome X, cinobufotalin, Bronchitis, Chronic | Altered Intercellular Communication | Here, we studied the following: (1) the frequency of the coexisting metabolic syndrome in patients with chronic bronchitis (CB) and COPD of different severities; and (2) its association with systemic inflammation and physical inactivity. | 19542257 |
| ARCN1 gene, Inflammation, Metabolic Syndrome X, Chronic Obstructive Airway Disease, gold | Altered Intercellular Communication | In 30 patients with CB (normal spirometry finding) and in 170 patients with COPD (Global Initiative for Chronic Obstructive Lung Disease [GOLD] stages I to IV), we measured the characteristics of the metabolic syndrome, systemic inflammation (high-sensitivity C-reactive protein [hs-CRP], interleukin-6, fibrinogen), and the physical activity level. | 19542257 |
| Presenile dementia, Inflammation, "Alzheimers Disease | Altered Intercellular Communication | Systemic inflammation and the risk of Alzheimer's disease and dementia: a prospective population-based study. | 19542629 |
| Inflammation, "Alzheimers Disease", Data types - Address | Altered Intercellular Communication | Inflammation is suggested to be involved in the pathogenesis of Alzheimer's disease (AD). | 19542629 |
| Airway structure, Asthma, Chest Pain | Altered Intercellular Communication | The results suggest that the mechanism underlying chest pain that is relieved with asthma drugs can involve either an airway constriction pathway or a non-constrictive pathway presumably airway inflammation. | 19542762 |
| Multiple Myeloma, Inflammation | Altered Intercellular Communication | The main changes evidenced were ingrowing of the squamous epithelium (either from the matrix or mostly from the hyponichium) and chronic plasma-cell rich inflammation with prominent vascularization. | 19542917 |
| Inflammation, Organ Dysfunction Scores, Critical Illness | Altered Intercellular Communication | Serum resistin levels in critically ill patients are associated with inflammation, organ dysfunction and metabolism and may predict survival of non-septic patients. | 19545363 |
| Inflammation, Critical Illness | Altered Intercellular Communication | Therefore, resistin might represent a link between inflammation, acute phase response and insulin resistance in critically ill patients. | 19545363 |
| Inflammation, Critical Illness | Altered Intercellular Communication | We aimed to examine the correlation of serum resistin concentrations to parameters of inflammation, organ function, metabolism, disease severity and survival in critically ill patients. | 19545363 |
| Sepsis, Inflammation, Systemic Inflammatory Response Syndrome | Altered Intercellular Communication | Serum resistin concentrations are elevated in acute inflammation due to sepsis or systemic inflammatory response syndrome (SIRS). | 19545363 |
| Inflammation, Primary malignant neoplasm | Altered Intercellular Communication | Thus, the predominant features of global orbital metastatic cancer versus primary inflammation are highlighted in this presentation. | 19545850 |
| Pancreatitis | Altered Intercellular Communication | Serum amylase and lipase measurements are known biochemical markers of pancreatic inflammation and a recognized finding that may help diagnose acute pancreatitis. | 19548460 |
| Crohn Disease, Gastrointestinal inflammation | Altered Intercellular Communication | Crohn's Disease (CD), a chronic intestinal inflammation, is currently treated primarily by therapeutics which are directed against inflammatory responses. | 19549264 |
| Inflammation, Diabetic Retinopathy | Altered Intercellular Communication | There are conflicting data regarding relationships of systemic biomarkers of inflammation, hemostasis, and homocysteine with diabetic retinopathy. | 19549733 |
| Inflammation, Diabetic Retinopathy | Altered Intercellular Communication | There were few associations of novel markers of inflammation, hemostasis, and homocysteine with diabetic retinopathy after controlling for established risk factors. | 19549733 |
| Malignant tumor of colon, Inflammation | Altered Intercellular Communication | Because chronic inflammation is implicated in several pathologic conditions in humans, including cancers of the colon, anti-inflammatory compounds may be useful chemopreventive agents against colon cancer. | 19549798 |
| Tumor necrosis, Inflammation | Altered Intercellular Communication | Tumor necrosis factor-alpha (TNF-alpha) and interleukin-6 (IL-6) are among the sensitive markers of systemic inflammation. | 19551157 |
| Filariasis, Periorbital region | Altered Intercellular Communication | The clinical presentation of filariasis is not always straightforward, and a high index of suspicion is necessary in cases presenting with orbital or periorbital inflammation. | 19551686 |
| Fibrous | Altered Intercellular Communication | Stenoses were inflammation-dominated with various narrowing of the lumen (type I) in 16.1% of patients, fibrous and web-associated, predominant incomplete (luminal narrowing <50%, type II) in 18.3%, and fibrous, predominant high-grade (luminal narrowing >50%, type III) in 66.6%. | 19551851 |
| Inflammation, Venous Thrombosis | Altered Intercellular Communication | Common hemostasis and inflammation gene variants and venous thrombosis in older adults from the Cardiovascular Health Study. | 19552680 |
| Inflammation, Thrombosis, vinyltriethoxysilane | Altered Intercellular Communication | We tested 290 common SNPs within 51 thrombosis and inflammation genes for association with VTE in the Cardiovascular Health Study, a large, prospective cohort of older adults followed for up to 12 years. | 19552680 |
| Choroidal Neovascularization, Inflammation, Fibrosis Assessment, neuron death | Altered Intercellular Communication | The focus on more effective blockade of choroidal neovascularization has shifted to include control of additional processes implicated in disease progression, such as neural death, inflammation, or fibrosis. | 19553800 |
| Inflammation, Fibrosis Assessment, Choroidal Neovascularization, Unspecified visual loss | Altered Intercellular Communication | Although there is likely to be a strong interrelationship between choroidal neovascularization and inflammation that contributes to advanced stages of disease progression, including fibrosis, combining treatment strategies may enlarge the opportunity to prevent both early and late vision loss. | 19553800 |
| Inflammation | Altered Intercellular Communication | Are markers of inflammation more strongly associated with risk for fatal than for nonfatal vascular events? | 19554082 |
| Brain Injuries | Altered Intercellular Communication | We hypothesized that markers of brain damage discovered by proteomic strategies and inflammation-related proteins could individually or in combination indicate the CNS invasion by the parasite. | 19554086 |
| Inflammation | Altered Intercellular Communication | It usually involves one hemisphere with focal cortical inflammation. | 19555404 |
| Inflammation, Hepatobiliary Disorder, Non-alcoholic Fatty Liver Disease, Fibrosis Assessment | Altered Intercellular Communication | Non-alcoholic fatty liver disease (NAFLD) is a spectrum of liver disease characterised by accumulation of large-droplet fat in hepatocytes with possible progression to inflammation and fibrosis. | 19556219 |
| Inflammation | Altered Intercellular Communication | Lack of response in 12% of cases suggests the presence of not screened viruses or mechanisms of damage and inflammation not susceptible to immunosuppression. | 19556262 |
| Inflammation, Diabetes Mellitus | Altered Intercellular Communication | However, PET is affected by several factors, including diabetes and inflammation. | 19556380 |
| Inflammation, Idiopathic Pulmonary Fibrosis | Altered Intercellular Communication | Chronic inflammation is implicated in idiopathic pulmonary fibrosis (IPF) pathogenesis and is associated with persistent activation of immune responses. | 19556741 |
| Airway structure, Asthma | Altered Intercellular Communication | The fractional concentration of exhaled nitric oxide (FeNO) appears to be a good marker for airway inflammation in children with asthma. | 19557209 |
| Airway structure | Altered Intercellular Communication | Exposure to different types of pets may have disparate effects on airway inflammation. | 19557209 |
| Inflammation | Altered Intercellular Communication | In the central nervous system glial-derived S100B protein has been associated with inflammation via nitric oxide (NO) production. | 19558426 |
| Inflammation, Diabetes Mellitus, Non-Insulin-Dependent, Obesity | Altered Intercellular Communication | Systemic chemerin is related to inflammation rather than obesity in type 2 diabetes. | 19558533 |
| Inflammation, Diabetes Mellitus, Non-Insulin-Dependent, Obesity | Altered Intercellular Communication | The adipokine chemerin modulates the function of innate immune cells and may link obesity and inflammation, and therefore, a possible relation of chemerin to inflammatory proteins in obesity and type 2 diabetes (T2D) was analysed. | 19558533 |
| Inflammation, Liver Cirrhosis | Altered Intercellular Communication | As visceral fat contributes to systemic inflammation, chemerin was measured in portal venous (PVS), hepatic venous (HVS) and systemic venous (SVS) blood of patients with liver cirrhosis. | 19558533 |
| Inflammation, Diabetes Mellitus, Non-Insulin-Dependent, Obesity | Altered Intercellular Communication | Visceral fat is not a major site of chemerin release, and elevated systemic levels of chemerin in obesity and T2D seem to be associated with inflammation rather than body mass index. | 19558533 |
| Tolosa-Hunt Syndrome, Cranial third nerve paresis, Methylated spirit, Necrotizing granulomatous inflammation | Altered Intercellular Communication | Tolosa-Hunt syndrome (THS) is characterized by unilateral painful ophthalmoplegia with oculomotor paresis, associated with an idiopathic granulomatous inflammation involving the cavernous sinus, with a typical relapsing-remitting course. | 19558537 |
| Deficiency of butyryl-CoA dehydrogenase, Inflammation | Altered Intercellular Communication | Endoscopic patterns of SCAD may range from mild to severe inflammation. | 19558591 |
| Inflammation, Cardiovascular Diseases, Acidosis, Anemia, Sarcopenia, Hypertension, CTCAE, Chronic Kidney Diseases | Altered Intercellular Communication | The odds of frailty associated with chronic kidney disease were only marginally attenuated with additional adjustment for sarcopenia, anemia, acidosis, inflammation, vitamin D deficiency, hypertension, and cardiovascular disease. | 19559169 |
| Inflammation, Intestines, Small | Altered Intercellular Communication | Previous workup was significant for eosinophilic inflammation in the antrum and a video capsule study showing erythematous lesions in the small bowel. | 19559431 |
| Inflammation, Fibrosis Assessment, Fatty degeneration, Fatty Liver Disease, Balloon Dilatation | Altered Intercellular Communication | NASH was defined as steatosis, lobular inflammation, and ballooning degeneration with or without Mallory-Denk bodies and/or fibrosis. | 19559819 |
| Presenile dementia, Inflammation, "Alzheimers Disease", Data types - Address | Altered Intercellular Communication | C-reactive protein (CRP) is a nonspecific marker of inflammation that is increased in the brain and serum of patients with Alzheimer's disease (AD), and has been associated with increased risk of developing dementia. | 19560102 |
| Presenile dementia, Inflammation | Altered Intercellular Communication | Inflammation increases with age, and the number of people reaching age 90 years and older is growing, making the association between inflammation and dementia increasingly relevant. | 19560102 |
| Communicable Diseases, Inflammation | Altered Intercellular Communication | Interleukin-1beta (IL-1beta) is involved in the regulation of sickness behaviour in response to infection and inflammation in animals. | 19560535 |
| Inflammation, Sore to touch, Swelling | Altered Intercellular Communication | All of the patients had inflammation, swelling, and localized tenderness. | 19560565 |
| Inflammation, Comorbidity | Altered Intercellular Communication | Glomerular filtration rate less than 60 mL/min/1.73 m(2) estimated from serum cystatin C level, comorbidity, medications, and markers of inflammation and hemostasis. | 19560852 |
| Peripheral Vascular Diseases, Vascular Diseases, Inflammation | Altered Intercellular Communication | To objectively assess the presence of polyvascular disease in patients with peripheral arterial disease and its relation to inflammation and clinical risk factors. | 19560948 |
| Inflammation, Vascular Diseases | Altered Intercellular Communication | The level of systemic inflammation, reflected by hs-CRP levels, is moderately associated with the extent of polyvascular disease. | 19560948 |
| Inflammation, Synovial Hypertrophy | Altered Intercellular Communication | Moreover, PD-positive synovial hypertrophy identifies an ongoing inflammation even during remission and predicts short-term relapse. | 19561156 |
| Pulmonary Complication, Pneumonitis | Altered Intercellular Communication | Delivery of a potent glucocorticoid such as 17-BMP to the pulmonary artery after oral dosing of BDP may be useful in modulating pulmonary inflammation and preventing the development of non-infectious pulmonary complications after allogeneic HCT. | 19561649 |
| Inflammation, Perforation (observation) | Altered Intercellular Communication | The CRP value showed a strong correlation with respect to the grade of inflammation and perforation. | 19562239 |
| Pharyngitis, Gorontalo Language | Altered Intercellular Communication | Indeed, in 40% of patients, radiographic signs were found that indicated nonspecific hypertrophy of the lingual tonsil and/or palatine tonsils and nonspecific signs of chronic pharyngeal inflammation, and GORD was identified in 93% of patients, which in 40% of cases extended to the proximal third of the oesophagus. | 19562267 |
| Inflammation, hepcidin | Altered Intercellular Communication | Hepcidin, a liver-derived peptide induced by iron overload and inflammation, is a major regulator of iron homeostasis. | 19563467 |
| Inflammation, hepcidin, Anemia | Altered Intercellular Communication | We studied the associations between circulating hepcidin levels and various laboratory parameters related to anaemia and/or inflammation in 20 patients on chronic haemodialysis. | 19563467 |
| Pyoderma Gangrenosum | Altered Intercellular Communication | Pyoderma gangrenosum, in contrast, is a noninfectious inflammatory condition of the skin that typically does not require surgical management. | 19563941 |
| Pain Distress Question, Inflammation, Fever, CTCAE, Communicable Diseases, Adverse Event Associated with Constitutional Symptoms | Altered Intercellular Communication | Back pain in presence of fever, constitutional symptoms, and/or high inflammation markers should alert physicians for spinal infection. | 19564756 |
| Inflammation, Neoplasms | Altered Intercellular Communication | Physical examination revealed a huge tumor in the right lower leg without signs of inflammation. | 19564830 |
| Inflammation, Metabolic Syndrome X | Altered Intercellular Communication | Obesity-induced chronic inflammation is a key component in the pathogenesis of insulin resistance and metabolic syndrome. | 19565174 |
| Inflammation | Altered Intercellular Communication | It has been suggested that proinflammatory cytokines and low-grade systemic inflammation activate bone resorption and may lead to reduced bone mineral density (BMD). | 19565174 |
| Inflammation, Acute anterior uveitis | Altered Intercellular Communication | Enthesis inflammation in recurrent acute anterior uveitis without spondylarthritis. | 19565479 |
| Refractory anemias, Have Autoimmune or Inflammatory Condition | Altered Intercellular Communication | This study was undertaken to characterize the disease specificity and function of pan-DR-binding Hsp60-derived epitopes as possible modulators of autoimmune inflammation in RA. | 19565483 |
| Refractory anemias, Inflammation, Damage | Altered Intercellular Communication | The purpose of this study was to examine the hypothesis that adipocytokines modulate inflammation and radiographic joint damage in patients with RA. | 19565493 |
| Refractory anemias, Inflammation | Altered Intercellular Communication | Concentrations of all adipocytokines were significantly higher in RA patients than in controls; for visfatin and adiponectin, this association remained significant after adjusting for BMI, inflammation, or both. | 19565493 |
| Refractory anemias, Inflammation | Altered Intercellular Communication | The concentration of OPN was significantly elevated in RA patients and appeared to correlate with the serum levels of inflammation markers and increased expression of MCP-1 or MIP-1beta in monocytes in RA patients. | 19565503 |
| Inflammation, Extensively Drug-Resistant Tuberculosis | Altered Intercellular Communication | [Serum nitric oxide level in the assessment of systemic inflammation in patients with drug-resistant pulmonary tuberculosis]. | 19565813 |
| Inflammation, Mild cognitive disorder, Metabolic Syndrome X | Altered Intercellular Communication | Metabolic syndrome, inflammation, and nonamnestic mild cognitive impairment in older persons: a population-based study. | 19568151 |
| Inflammation, Impaired cognition, Metabolic Syndrome X, ETV3 wt Allele | Altered Intercellular Communication | The metabolic syndrome (MetS) is more strongly associated with cognitive impairment in the presence of inflammation. | 19568151 |
| Inflammation, millicurie, Anomia, ETV3 wt Allele | Altered Intercellular Communication | This study investigated the association between MetS with or without inflammation and MCI [amnestic (a-MCI) and nonamnestic (na-MCI)]. | 19568151 |
| Inflammation, ETV3 wt Allele | Altered Intercellular Communication | The combined presence of MetS and high levels of inflammation is associated with na-MCI in this elderly cohort, and suggests etiologic differences in MCI subtypes. | 19568151 |
| Malignant neoplasm of urinary bladder | Altered Intercellular Communication | Hormonal factors, possibly related to reproductive characteristics, may play a role in the risk of bladder cancer among women. | 19568699 |
| Malignant neoplasm of urinary bladder | Altered Intercellular Communication | Women have a lower risk of bladder cancer than men, and hormonal factors related to childbearing may play a role. | 19568699 |
| Papilledema, Uveitis | Altered Intercellular Communication | They were treated with high-dose corticosteroid therapy, and several weeks later, both the uveal inflammation and optic disc swelling disappeared. | 19568763 |
| Atrial Fibrillation, Atrial Fibrillation by ECG Finding, Hypertension, CTCAE, Inflammation | Altered Intercellular Communication | Numerous evidence has suggested that either hypertension or atrial fibrillation (AF) is associated with systemic inflammation. | 19569080 |
| Inflammation, Atrial Fibrillation | Altered Intercellular Communication | The correlation between PPARgamma inflammation and AF is still unknown. | 19569080 |
| Inflammation, Hypertensive (finding) | Altered Intercellular Communication | In hypertensive patients, increased inflammatory cytokines were associated with increased incidence of AF and atrial remodeling; PPARgamma may be involved in the pathogenesis of AF by regulation of inflammation. | 19569080 |
| Inflammation, Dermatomyositis, Childhood Type | Altered Intercellular Communication | Juvenile dermatomyositis (JDM) is a rare systemic disease of unknown etiology characterized by inflammation of the muscle, skin and digestive tract, with variable outcome. | 19569283 |
| Inflammation | Altered Intercellular Communication | Adiponectin plays an important role in the regulation of tissue inflammation and insulin sensitivity. | 19570238 |
| Inflammation | Altered Intercellular Communication | This highly important observation may result from a setting of prevailing chronic subclinical inflammation. | 19570555 |
| Inflammation, Acute myocardial infarction, Atrial Fibrillation by ECG Finding | Altered Intercellular Communication | Relation of inflammation and left atrial remodeling in atrial fibrillation occurring in early phase of acute myocardial infarction. | 19570585 |
| Inflammation, Atrial Fibrillation, Atrial Fibrillation by ECG Finding | Altered Intercellular Communication | Inflammation is frequently associated with the development of atrial fibrillation (AF). | 19570585 |
| Inflammation, Chronic granulomatous disease | Altered Intercellular Communication | Thus we speculate that the lack of a functional NADPH oxidase results in impaired neutrophil clearance and the exaggerated inflammation that is characteristic for CGD. | 19570889 |
| atherosclerotic | Altered Intercellular Communication | Pericardial fat (ie, fat around the heart) may have a direct role in the atherosclerotic process in coronary arteries through local release of inflammation-related cytokines. | 19571212 |
| Inflammation, Edema | Altered Intercellular Communication | These data support the hypothesis that, in addition to the adaptive immune responses, the complement system is involved in the pathogenesis of CRSwNP and may contribute to typical features such as edema and granulocytic inflammation. | 19572264 |
| Hypoglycemia, Diabetes Mellitus | Altered Intercellular Communication | Comparing hormonal and symptomatic responses to experimental hypoglycaemia in insulin- and sulphonylurea-treated Type 2 diabetes. | 19573114 |
| Pain Distress Question, Inflammation, Neoplasms | Altered Intercellular Communication | The patient presented with a tumor in the right breast that had appeared 6 months earlier with no pain, signs of inflammation, or nipple secretion. | 19573643 |
| Pneumonitis | Altered Intercellular Communication | The most foolproof way to promote survival in epidemics of potentially lethal influenza is to target, not highly mutable viral proteins, but rather intracellular signaling pathways which promote viral propagation or lung inflammation. | 19573997 |
| Inflammation, Influenza | Altered Intercellular Communication | NF-kappaB, activated in influenza-infected lung epithelial cells and macrophages, is one likely target in this regard, as it plays a role both in viral replication and in the excessive lung inflammation often evoked by influenza infection. | 19573997 |
| ARCN1 gene, Inflammation, Chronic Obstructive Airway Disease, Metabolic Syndrome X | Altered Intercellular Communication | There is some evidence that chronic obstructive pulmonary disease (COPD) and metabolic syndrome may be related, perhaps through systemic inflammation, which is common to both. | 19574332 |
| Inflammation, Kidney Diseases | Altered Intercellular Communication | Blood samples were collected for measurement of vascular risk markers (kidney disease, inflammation, nutrition, calcium phosphate and OPG). | 19574342 |
| Inflammatory abnormality of the eye | Altered Intercellular Communication | This report illustrates the spectrum of ocular inflammation caused by accidental inoculation of latex of Euphorbia plant. | 19574703 |
| Inflammation, Uveitis | Altered Intercellular Communication | Laboratory investigations for uveitis were negative and the patient required systemic and intensive topical steroids with cycloplegics to control the inflammation. | 19574707 |
| Hemorrhage, Traumatic injury, Vascular System Injuries | Altered Intercellular Communication | Bleeding was caused by iatrogenic vessel injury (6 patients), malignancy/inflammation (5 patients) and trauma (3 patients). | 19575344 |
| Inflammation, Ulcer | Altered Intercellular Communication | It may contribute to reduced perfusion, poor ulcer healing, and sustained chronic inflammation. | 19575355 |
| Inflammation, Bacterial resistance, Restless Legs Syndrome | Altered Intercellular Communication | The aim of this study was to determine if RLS was associated with CD because both are associated with iron deficiency, inflammation, and bacterial overgrowth. | 19575360 |
| Inflammation, Inflammatory dermatosis, Pruritus | Altered Intercellular Communication | Topical calcineurin inhibitors such as tacrolimus (FK506) ameliorate cutaneous inflammation and associated pruritus in an array of inflammatory dermatoses. | 19575757 |
| Inflammation | Altered Intercellular Communication | In conclusion, these results suggest that the previously reported association between poor fitness and low-grade inflammation may be largely attributable to increased visceral AT accumulation and its associated state of insulin resistance, conditions frequently observed in subjects with poor cardiorespiratory fitness. | 19576354 |
| Inflammation, Keratitis, Herpetic | Altered Intercellular Communication | Herpes simplex virus keratitis: histopathologic inflammation and corneal allograft rejection. | 19576497 |
| Herpes Simplex Infections, Inflammation, Human herpes simplex virus, Keratitis | Altered Intercellular Communication | To identify whether histopathologic and immunoassay biomarkers of inflammation are predictive for allograft rejection after penetrating keratoplasty (PKP) for herpes simplex virus (HSV) keratitis. | 19576497 |
| Keratitis | Altered Intercellular Communication | Although 81% of patients had clinically quiescent disease, histopathology revealed that 74% had active corneal inflammation, a finding that was associated with the presence of clinical neovascularization (P = 0.01). | 19576497 |
| Inflammation | Altered Intercellular Communication | Corneal specimens demonstrating inflammation had significantly increased IL-8 (P = 0.0005) and MCP-1 (P = 0.003) levels, and greater immunoreactivity for HLA-DR and ICAM-1 when compared with specimens without inflammation. | 19576497 |
| Inflammation, Atherosclerosis | Altered Intercellular Communication | Inflammation plays a key role in the pathogenesis of atherosclerosis and an enhanced inflammatory status has a negative impact on patient outcome. | 19577753 |
| Primary malignant neoplasm, Inflammatory abnormality of the eye | Altered Intercellular Communication | Overall and cancer related mortality among patients with ocular inflammation treated with immunosuppressive drugs: retrospective cohort study. | 19578087 |
| Inflammatory abnormality of the eye | Altered Intercellular Communication | Patients 7957 US residents with non-infectious ocular inflammation, 2340 of whom received immunosuppressive drugs during follow up. | 19578087 |
| Inflammation, Acute Coronary Syndrome, Atherosclerosis | Altered Intercellular Communication | Inflammation plays a pivotal role in the pathogenesis of atherosclerosis and coronary syndromes. | 19578791 |
| Inflammation | Altered Intercellular Communication | Data indicate that the complement proteins play a crucial role in the link between inflammation and atherogenesis. | 19578791 |
| Refractory anemias, Inflammation | Altered Intercellular Communication | In RA, endothelial activation (as sEsel) correlates with classical markers of inflammation and is reduced by intensive anti-inflammatory medications. | 19578810 |
| Granulomatous inflammation | Altered Intercellular Communication | Lung biopsy obtained by wedge resection showed granulomatous inflammation with extensive multinuclear giant cells involving the lung parenchyma and vascular structures. | 19578851 |
| Inflammation, Lesion of retina | Altered Intercellular Communication | The macular and retinal lesions, the etiological role of toxic agent, the compression and the inflammation of the optic nerve all have to be excluded. | 19579669 |
| Communicable Diseases, inflammation or infection | Altered Intercellular Communication | Procalcitonin role in differential diagnosis of infection stages and non infection inflammation. | 19579976 |
| Communicable Diseases, inflammation or infection | Altered Intercellular Communication | The aim of this study is evaluation of procalcitonin role in the diagnosis of infectious and non infectious inflammation. | 19579976 |
| Inflammation, Chronic Obstructive Airway Disease, Bronchitis | Altered Intercellular Communication | Among adults <50 years old, chronic bronchitis unaccompanied by airflow limitation may represent an early marker of susceptibility to the effects of cigarette smoking on systemic inflammation and long-term risk for chronic obstructive pulmonary disease and all-cause mortality. | 19581277 |
| Inflammation | Altered Intercellular Communication | Laboratory evidence of inflammation was found in 87% and RF in 78% of the patients. | 19581382 |
| Refractory anemias, Tumor necrosis, Rheumatoid Arthritis, Inflammation | Altered Intercellular Communication | Tumor necrosis factor-alpha (TNF-alpha) plays a central role in inflammation, and it has been directly implicated in the pathogenesis of rheumatoid arthritis (RA). | 19582456 |
| metabolic disturbance, Obesity | Altered Intercellular Communication | To gain insight in the interaction between innate immune system and metabolic disturbances (obesity and insulin resistance), we investigated the relationship between circulating lactoferrin and chronic inflammation-associated insulin resistance according glucose tolerance status in Caucasian population. | 19584176 |
| Inflammation, Coronary Artery Disease, Endothelial dysfunction | Altered Intercellular Communication | Inflammation but not endothelial dysfunction is associated with the severity of coronary artery disease in dyslipidemic subjects. | 19584917 |
| Inflammation, Endothelial dysfunction, Atherosclerosis | Altered Intercellular Communication | Endothelial dysfunction and inflammation play a key role in the development of atherosclerosis. | 19584917 |
| Intraocular inflammation, Sarcoidosis, Neurosarcoidosis | Altered Intercellular Communication | We found a higher incidence of ocular manifestations, including intraocular inflammation in neurosarcoidosis compared to that in systemic sarcoidosis elsewhere. | 19585359 |
| Intraocular inflammation, Sarcoidosis, Neurologic Symptoms | Altered Intercellular Communication | Patients with neurological symptoms and associated intraocular inflammation should have a routine work-up for sarcoidosis. | 19585359 |
| Inflammatory abnormality of the eye | Altered Intercellular Communication | To evaluate the control of ocular inflammation and the steroid sparing effect in patients with sarcoidosis-associated uveitis treated with mycophenolate mofetil (MMF). | 19585361 |
| Carcinoma of lung | Altered Intercellular Communication | Our results suggest that hormonal factors, related to early menopause and/or ovary removal, may play a role in the risk of lung cancer. | 19585503 |
| Osteoporosis | Altered Intercellular Communication | Hormonal changes associated with ageing predispose to osteoporosis also in men, although secondary causes in the pathogenesis of osteoporosis become more pronounced. | 19585908 |
| millicurie, neuron death, Data types - Address | Altered Intercellular Communication | Thus, the available, albeit limited, data suggests that MCI is associated with the early stages of the neurobiological and neuropathological changes that culminate in the florid lesions of AD; including the accumulation of neuritic plaques, neurofibrillary tangles, synaptic and neurotransmitter associated deficits, and significant neuronal cell death. | 19585952 |
| Inflammation, Diabetic Foot | Altered Intercellular Communication | Ultrasonographic and thermographic screening for latent inflammation in diabetic foot callus. | 19586674 |
| Diabetic Foot, Ulcer | Altered Intercellular Communication | Inflammation within the diabetic foot callus may be an earliest, predicting symptom of foot ulcer developing later. | 19586674 |
| Inflammation, diabetic | Altered Intercellular Communication | The inflammation signs were detected by both of the two techniques in 10% of the calli in the diabetic group. | 19586674 |
| Inflammation, diabetic | Altered Intercellular Communication | The inflammation signs presented here were specifically observed in the diabetic group. | 19586674 |
| Glomerulonephritis, Nephritis | Altered Intercellular Communication | (Monocyte chemoattractant protein 1 MCP-1) has been shown to be locally up regulated in glomerulonephritis and recent studies have pointed out MCP-1 as a promising marker of renal inflammation. | 19587833 |
| Delirium | Altered Intercellular Communication | The pathophysiology of delirium remains elusive though neurotransmitters and their precursor large neutral amino acids (LNAAs) may play a role. | 19588122 |
| Inflammation | Altered Intercellular Communication | Laboratory tests showed inflammation, with an erythrocyte sedimentation rate of 90 mm/h and C-reactive protein 8 mg/l. | 19588143 |
| Vasculitis, Vasculitis, CTCAE, Disease | Altered Intercellular Communication | Vasculitis is a disorder characterized by inflammation of blood vessels. | 19588144 |
| Inflammation | Altered Intercellular Communication | In some cases the disease is manifested only with symptoms and signs of systemic inflammation (e.g. | 19588144 |
| Inflammation, Glucose Intolerance (disease), Obesity, Cardiovascular Diseases | Altered Intercellular Communication | Obesity leads to increased risk of cardiovascular disease and glucose intolerance, which are phenomena of chronic inflammation. | 19588793 |
| Inflammation, Obesity | Altered Intercellular Communication | This study was performed to determine whether a higher body mass index (BMI) and central obesity are associated with low-grade inflammation. | 19588793 |
| ACSM3 gene, Subarachnoid Hemorrhage, Aneurysmal, Inflammation Mediators, Cerebral Vasospasm | Altered Intercellular Communication | Cerebral vasospasm after aneurysmal subarachnoid hemorrhage (SAH) has been hypothesized to occur because of both inflammation-mediated sustained contraction of smooth muscle cells and vascular remodeling. | 19589197 |
| Acute inflammation | Altered Intercellular Communication | It is concluded that MPO and IL-17 are powerful indicators of acute coronary inflammation, however the data set was very small, so larger prospective studies are required. | 19589271 |
| Inflammation | Altered Intercellular Communication | Past work has focused on the role of T cells and myeloid cells in mediating chronic gastrointestinal and systemic inflammation. | 19589946 |
| Intraocular inflammation | Altered Intercellular Communication | In the ranibizumab group, there were 2 events of transiently increased intraocular pressure (1.1%) and 1 event (0.53%) of intraocular inflammation following injection. | 19590252 |
| Parkinson Disease, Impaired cognition, Pervasive Development Disorder, Presenile dementia | Altered Intercellular Communication | Impairment of multiple neurotransmitter networks, including acetylcholine, may contribute to the cognitive impairment in patients with Parkinson disease with dementia (PDD). | 19590387 |
| HD Term Type, Thrombosis, Inflammation | Altered Intercellular Communication | Vascular access thrombosis (VAT) is a major cause of morbidity in chronic hemodialysis (HD) patients and is characterized by chronic inflammation. | 19590503 |
| Chronic inflammation | Altered Intercellular Communication | Pulse pressure (PP) is positively associated with chronic inflammation. | 19590503 |
| Inflammation, Necrosis, Medial calcification, Intimal proliferation, Adventitia | Altered Intercellular Communication | Both ends of all specimens were evaluated by a blinded pathologist for intimal hyperplasia, medial inflammation, medial calcification, periarterial tissue or fat necrosis, adventitial inflammation, adventitial necrosis, and adventitial neovascularization. | 19590587 |
| Inflammation, Intimal proliferation, Necrosis | Altered Intercellular Communication | The distal ends of the TRA group showed significantly more intimal hyperplasia (73.3% vs 21.1%; p = 0.03), periarterial tissue or fat necrosis (26% vs 0%; p = 0.02), and more adventitial inflammation (33.3% vs 0%; p = 0.01) than the distal ends of the NCA group. | 19590587 |
| Inflammation, Intimal proliferation | Altered Intercellular Communication | The distal ends of the TRA group also showed significantly more intimal hyperplasia (73.3% vs 26.6%; p = 0.03) and adventitial inflammation (33.3% vs 0%; p = 0.01) than the proximal ends of the same arteries. | 19590587 |
| Inflammation, Arterial Injury, Intimal proliferation, Necrosis | Altered Intercellular Communication | Transradial catheterization induces significant histological changes suggestive of radial artery injury limited to the puncture site in the form of intimal hyperplasia, medial inflammation, and tissue necrosis. | 19590587 |
| Inflammation, Mineral dust | Altered Intercellular Communication | Proximal airways demonstrated little mineral dust accumulation, but membranous and respiratory bronchioles had wall thickening, remodeling, and inflammation associated with carbonaceous and mineral dust deposition. | 19590695 |
| Pain Distress Question, Inflammation, Fever, CTCAE, Brucellosis, Familial Mediterranean Fever, MULTISYSTEM DISORDER | Altered Intercellular Communication | Familial Mediterranean fever (FMF) is a genetic multisystem disorder of unknown etiology characterized by recurrent episodes of fever and pain due to acute inflammation of the peritoneum, synovia, or pleura. | 19590876 |
| Inflammation, Demyelination | Altered Intercellular Communication | Mitochondrial alterations might occur as a response to demyelination and inflammation, since demyelination leads to an increased energy demand in axons and could thereby affect the number, distribution and activity of mitochondria. | 19591199 |
| Inflammation, Coronary Artery Disease, Endothelial dysfunction | Altered Intercellular Communication | In conclusion, insulin resistance, endothelial dysfunction, and inflammation are important cardiovascular risk factors in coronary artery disease patients; and L-arginine seems to have anti-inflammatory and metabolic advantages in these patients. | 19592054 |
| Inflammation, Obesity | Altered Intercellular Communication | These results suggest that LOX-1 induction may be related to adipocyte metabolism, inflammation, and immune response associated with obesity. | 19592055 |
| Inflammation, Beta-cell dysfunction | Altered Intercellular Communication | Subclinical inflammation leads to insulin resistance and beta-cell dysfunction. | 19592635 |
| Inflammation, Hydronephrosis | Altered Intercellular Communication | Clinical presentation is influenced by sex, severity of inflammation and presence of hydronephrosis. | 19593223 |
| Vasculitis | Altered Intercellular Communication | Imaging studies have revealed large vessel inflammation in at least 60% of patients with GCA. | 19593227 |
| Inflammation, Fibrosis Assessment, Fatty degeneration | Altered Intercellular Communication | On liver biopsy (n = 35) 80% had evidence of inflammation, 57% had fibrosis, and 9% had steatosis. | 19593250 |
| Rheumatoid Arthritis | Altered Intercellular Communication | [MMP- and FAP-mediated non-inflammation-related destruction of cartilage and bone in rheumatoid arthritis]. | 19593575 |
| Neoplasms, Synovitis, Refractory anemias, Giant Cell Tumors, Rheumatoid Arthritis | Altered Intercellular Communication | Due to morphological similarities of high-grade synovitis in rheumatoid Arthritis (RA) and mesenchymal, semimalignant tumors and the hypothesis that RA progression is not only inflammation-related, but also determined by tumor-like mechanisms, a comparison was made between expression profiles of RA, giant cell tumor of bone (GCT) and normal synovium (ND). | 19593575 |
| Inflammation, Metabolic Syndrome X | Altered Intercellular Communication | Omega-3 fatty acid supplements improve the cardiovascular risk profile of subjects with metabolic syndrome, including markers of inflammation and auto-immunity. | 19593941 |
| Thyroid associated opthalmopathies, Inflammatory disease of mucous membrane | Altered Intercellular Communication | Histological and radiological signs indicative for chronic sinus mucosal inflammation in Graves' ophthalmopathy. | 19593970 |
| Acute and chronic inflammation | Altered Intercellular Communication | A histological examination of the sinus mucosa indicative for chronic polypoid inflammation was present in 25 patients. | 19593970 |
| Eosinophilic disorder, Inflammation | Altered Intercellular Communication | Six patients had mucosal changes suggesting chronic non-polypoid inflammation with tissue eosinophilia on histological exam. | 19593970 |
| Actinomycosis, Inflammation, Neoplasms | Altered Intercellular Communication | Although rare, actinomycosis of the caecum should be taken into consideration in the differential diagnosis of tumorous lesions of the caecoascending part of the colon, particularly if the tumour is associated with inflammation. | 19594073 |
| Crohn Disease, Inflammation, Ulcerative Colitis | Altered Intercellular Communication | In ulcerative colitis and Crohn's disease, prostaglandins may be involved in the pathogenesis of inflammation, and increased expression of cyclo-oxygenase-2 (COX-2) has been detected. | 19594490 |
| Glomerulitis Assessment, Capillaritis, Interstitial inflammation | Altered Intercellular Communication | Transplant glomerulitis and interstitial inflammation were present in all 13 biopsies, and peritubular capillaritis was present in 12 of 13 biopsies, interstitial fibrosis/tubular atrophy in 13, and the thickening of the peritubular capillary (PTC) basement membrane in 11. | 19594595 |
| Pulmonary artery structure | Altered Intercellular Communication | Inflammation changes including dense plural adhesions, pulmonary artery adhesions and calcified lymph nodes were managed endoscopically. | 19595235 |
| Inflammation, Tissue Adhesions | Altered Intercellular Communication | Chronic inflammation induced adhesions is the key limiting factor for thoracoscopic lobectomy for benign diseases. | 19595235 |
| Inflammation, Atherosclerosis | Altered Intercellular Communication | Early life origins of low-grade inflammation and atherosclerosis risk in children and adolescents. | 19595364 |
| Inflammation | Altered Intercellular Communication | Our results showed that smaller birth weight is associated with chronic low-grade inflammation in children and adolescents. | 19595364 |
| Inflammation, Atherosclerosis | Altered Intercellular Communication | Inflammation plays a central role in the development and progression of atherosclerosis, and inflammatory markers have been reported to predict cardiovascular events. | 19595382 |
| Inflammation | Altered Intercellular Communication | Percutaneous core needle biopsies showed differentiated pancreatic tissue with chronic inflammation and cystic transformation. | 19595516 |
| Inflammation | Altered Intercellular Communication | Thus, our data suggest, for the first time, that the delicate balance between PTK and PTP is disturbed during aging and inflammation, both of which lead to NF-kappaB activation via NIK/IKK and MAPKs. | 19596065 |
| Inflammation, ciliary vesicle, Obesity | Altered Intercellular Communication | In the general population, obesity is associated with inflammation, decreased high-density lipoprotein (HDL) cholesterol, increased low-density lipoprotein (LDL) cholesterol, and triglycerides (TGs), all risk factors for CV disease. | 19596588 |
| Inflammation, Dyslipidemias, Kidney Failure | Altered Intercellular Communication | Renal failure is associated with dyslipidemia and inflammation in normal-weight patients. | 19596588 |
| Granulomatous inflammation | Altered Intercellular Communication | The epidemiologic association with bioaerosols and the presence of granulomatous inflammation support consideration of mycobacterial antigens. | 19596780 |
| Inflammation, Atherosclerosis | Altered Intercellular Communication | The results confirm adipokines' involvement in the process of inflammation and atherosclerosis: protective and antiinflammatory adiponectin effect and proatherogenic and proinflammatory leptin function. | 19597733 |
| Fibrosis Assessment, Interstitial inflammation | Altered Intercellular Communication | Renal pathology revealed cellular to fibrocellular crescents in 21 out of 23 glomeruli with interstitial inflammation and fibrosis. | 19601559 |
| Inflammation | Altered Intercellular Communication | Osteopontin (OPN) is a secreted glycoprotein demonstrated to play an important role in inflammation. | 19601999 |
| Inflammation, Aspergillosis | Altered Intercellular Communication | This suggested that these T2-hyperintense lesions may be due to secondary inflammation caused by aspergillosis and not the aspergillosis itself. | 19602790 |
| palladium, Inflammation, Elastosis perforans serpiginosa | Altered Intercellular Communication | We analyzed probes from patients with normal kidney function (n = 10), with normal kidney function and inflammation (n = 10), on PD without (n = 10) and with EPS (n = 9). | 19602904 |
| palladium, Inflammation, Appendicitis, CTCAE, Elastosis perforans serpiginosa | Altered Intercellular Communication | Vasculopathy was significantly more pronounced in EPS (normal 0.4 +/- 0.5, appendicitis 0.2 +/- 0.3, PD 1.0 +/- 0.7 and EPS 1.6 +/- 1.2; p < 0.0001) than in PD or inflammation (normal 30 +/- 16, appendicitis 82 +/- 48, PD 1,936 +/- 952 and EPS 2,613 +/- 1,209; p < 0.0001), whereas the density of vessels were decreased (normal 125 +/- 114, appendicitis 817 +/- 347, PD 81 +/- 57 and EPS 36 +/- 33; p < 0.0001). | 19602904 |
| Arterial Stiffness, Inflammation, Refractory anemias | Altered Intercellular Communication | Elevated plasma OPN levels are associated with increased arterial stiffness in RA patients, suggesting that this protein might represent a bridge protein between inflammation and the consequent joint damage and cardiovascular risk in RA patients. | 19603104 |
| ARCN1 gene, Inflammation | Altered Intercellular Communication | Increased expression of the Th17-related cytokines IL-17A, IL-22 and IL-23 in COPD patients may reflect their involvement, and that of specific IL-17-producing cells, in driving the chronic inflammation seen in COPD. | 19604272 |
| Inflammation | Altered Intercellular Communication | However, iNOS activity is stimulated during inflammation by cytokines such as TNF-alpha and the amount of NO produced by iNOS may be a 1,000-fold greater than that produced by endothelial NOS. | 19604438 |
| Inflammation, Metabolic Syndrome X | Altered Intercellular Communication | Correlation with clinical variables, laboratory markers of inflammation, metabolic syndrome features, adipokines and adhesion molecules was also assessed. | 19604438 |
| Inflammation | Altered Intercellular Communication | There was a minimal inflammatory backdrop consisting of lymphocytes but not plasma cells or acute inflammation. | 19606014 |
| Refractory anemias, Inflammation, ETV3 wt Allele | Altered Intercellular Communication | The prevalence and associations of the MetS in RA remain uncertain: systemic inflammation and anti-rheumatic therapy may contribute. | 19607680 |
| Inflammation | Altered Intercellular Communication | DARC-positive small vessels and capillary vessels were associated with sites of inflammation and their number was increased during episodes of acute lung rejection. | 19608592 |
| Inflammation | Altered Intercellular Communication | A common change that occurs with age in the central nervous system is an increase in microglial-associated inflammation. | 19609089 |
| Inflammation, Fibrosis Assessment | Altered Intercellular Communication | The surgical pathological findings of fibrosis and the severity of inflammation correlated with the MRI category in all cases. | 19610137 |
| Fibrosis Assessment, Gastrointestinal inflammation | Altered Intercellular Communication | The MRI categories also correlated with the presence and level of intestinal inflammation and fibrosis on surgical pathology, and may be of prognostic use in the management of CD patients. | 19610137 |
| Inflammation, Gangrene | Altered Intercellular Communication | Surgical intervention was performed with the findings of a perforated and gangrenous appendix and severe inflammation at the left side of the abdomen. | 19610564 |
| Asthma, Bronchitis | Altered Intercellular Communication | We hypothesized that c-kit and PDGF receptor inhibition may decrease bronchial inflammation and interfere with airway remodeling, which are crucial features of severe asthma. | 19614621 |
| Inflammation, Carcinogenesis | Altered Intercellular Communication | The aim was to determine whether qualitative and quantitative differences in perineoplastic inflammation in OTRs contribute to the increased carcinogenesis. | 19614769 |
| Inflammation | Altered Intercellular Communication | Considerable inflammation was observed in all intraepithelial SCC (inflammatory infiltrate depth 2.80 +/- 2.21 mm immunocompetent patients, 2.15 +/- 2.95 mm OTRs). | 19614769 |
| Immunocompetent, Inflammation | Altered Intercellular Communication | Inflammation was more pronounced in invasive SCC of immunocompetent patients (4.60 +/- 4.67 mm) and OTRs (3.30 +/- 5.90 mm) (P < 0.005). | 19614769 |
| Inflammation | Altered Intercellular Communication | Perineoplastic inflammation in intraepithelial SCC is pronounced both in immunocompetent patients and OTRs. | 19614769 |
| Inflammation | Altered Intercellular Communication | Markers of inflammation and increased serum calcium were significant predictors of increased carotid artery IMT. | 19614783 |
| Communicable Diseases | Altered Intercellular Communication | High mobility group box 1 (HMGB1), a nonhistone chromatin-associated protein, is implicated as a mediator of both infectious and non-infectious inflammatory conditions. | 19616266 |
| Diabetic Nephropathy | Altered Intercellular Communication | Which components of malnutrition-inflammation-atherosclerosis syndrome are more common in haemodialysis patients with diabetic nephropathy? | 19619183 |
| HD Term Type | Altered Intercellular Communication | Malnutrition-inflammation-atherosclerosis syndrome (MIA) in haemodialysis (HD) patients is a common clinical condition characterized by increased mortality rate. | 19619183 |
| Inflammation, Malnutrition, Atherosclerosis | Altered Intercellular Communication | Atherosclerosis frequently coexisted with inflammation in both groups (51.5% in DM and 20.0% in non-DM) and less frequently with malnutrition. | 19619183 |
| Inflammation, Malnutrition, Demographics Domain | Altered Intercellular Communication | The frequency of inflammation was only slightly higher in DM, while of malnutrition was similar. | 19619183 |
| Inflammation, Fibrosis Assessment | Altered Intercellular Communication | Typically, they are characterized by severe and increasingly painful inflammation, often accompanied by fibrosis and constriction of the anatomic channels needed for normal life, such as the small airways of the lungs and, in the present report, the urethra. | 19619201 |
| Kidney Failure, Chronic, Inflammation, Depressed mood, Impaired | Altered Intercellular Communication | As end-stage kidney disease (ESKD) is associated with chronic inflammation, impaired immunity and depressed lymphocyte numbers, we sought to determine whether altered TRPV1 (and related TRPV2) expression in immune cells might be a contributing factor. | 19619644 |
| Inflammation, ovarian neoplasm | Altered Intercellular Communication | Serum C-reactive protein (CRP) is a widely used biomarker of inflammation and has been previously shown to be a promising biomarker in patients with ovarian cancer. | 19619929 |
| Inflammation | Altered Intercellular Communication | Very late DES thrombosis is associated with histopathological signs of inflammation and intravascular ultrasound evidence of vessel remodeling. | 19620501 |
| Necrotizing granulomatous inflammation, Histiocytes, Necrosis, Brucellosis | Altered Intercellular Communication | Histopathological examination of the mass revealed chronic granulomatous inflammation characterized by central necrosis, histiocyte and lymphocyte infiltration and formation of giant cells, compatible with brucellosis. | 19621621 |
| ARCN1 gene, Inflammation, Chronic Obstructive Airway Disease | Altered Intercellular Communication | Chronic inflammation of the airways and lung parenchyma plays a major role in the pathogenesis of chronic obstructive pulmonary disease (COPD). | 19622350 |
| Inflammation, Dysplasia | Altered Intercellular Communication | The surgical specimen was a complex anastomosing inflammatory pseudopolyp 5 cm x 4 cm x 3 cm in size, with a focus of low-grade dysplasia in an area free of inflammation. | 19623327 |
| Inflammation, Myositis, CTCAE 5.0 | Altered Intercellular Communication | The pathogenic role of inflammation in inclusion body myositis (IBM) remains uncertain. | 19623629 |
| Inflammation, Waldenstrom Macroglobulinemia | Altered Intercellular Communication | The predominant type of inflammation seen in the lamina propria was lymphoplasmacytic in 85.5% cases. | 19624086 |
| Cataract, Acute inflammation, Secondary glaucoma | Altered Intercellular Communication | One year later, he had uncomplicated cataract extraction but developed prolonged postoperative inflammation and secondary glaucoma. | 19624348 |
| Airway structure, ARCN1 gene | Altered Intercellular Communication | This study further suggests cineole as an active controller of airway inflammation in COPD by intervening in the pathophysiology of airway inflammation of the mucus membrane. | 19624838 |
| Granuloma, Cutaneous, Traumatic injury | Altered Intercellular Communication | Sea urchin injuries have been associated with a variety of cutaneous lesions, ranging from acute, transient reactions, to more chronic inflammatory conditions that result in the formation of granulomas. | 19624987 |
| Inflammation, Metabolic Syndrome X, ETV3 wt Allele | Altered Intercellular Communication | Metabolic syndrome (MetS) features chronic inflammation and exaggerated postprandial triacylglyceride (TAG) responses. | 19625064 |
| Inflammation, Aortic Aneurysm, Abdominal | Altered Intercellular Communication | The influence of COX-2 single nucleotide polymorphisms on abdominal aortic aneurysm development and the associated inflammation. | 19625268 |
| Inflammation, Kidney Failure | Altered Intercellular Communication | Renal failure itself had such a strong prognostic impact that conventional factors such as poor myocardial function or inflammation were concealed. | 19626297 |
| Inflammation | Altered Intercellular Communication | Moreover, it is related to the epithelial-mesenchymal transition process and T cell differentiation associated with inflammation. | 19626374 |
| Inflammation | Altered Intercellular Communication | Baseline inflammation is not predictive of periprocedural troponin elevation after elective percutaneous coronary intervention. | 19626398 |
| Inflammation | Altered Intercellular Communication | Few data are available about the incidence and the relation to inflammation of troponin elevation following percutaneous coronary intervention (PCI), a potential predictor of longterm outcome. | 19626398 |
| Inflammation, myonecrosis | Altered Intercellular Communication | Baseline inflammation cannot predict onset of minor myonecrosis damage (expressed by troponin elevation) induced by PCI, a significant predictor of long-term outcome in this setting. | 19626398 |
| Nasopharyngeal Angiofibroma | Altered Intercellular Communication | Juvenile nasopharyngeal angiofibromas (JNAs) are rare benign lesions that express hormonal receptors. | 19626637 |
| Inflammation, Carcinogenesis | Altered Intercellular Communication | Chemokines are important in inflammation and in carcinogenesis. | 19627345 |
| Post-Traumatic Stress Disorder, Inflammation, Disease | Altered Intercellular Communication | Posttraumatic stress disorder (PTSD) has been associated with several somatic diseases, and low-grade inflammation may be one psychobiological mechanism mediating this relationship. | 19628221 |
| Post-Traumatic Stress Disorder, Inflammation | Altered Intercellular Communication | PTSD was diagnosed in 55 participants (1.8%), and low-grade inflammation (i.e. | 19628221 |
| Post-Traumatic Stress Disorder, Inflammation, Cardiovascular Diseases, Diabetes Mellitus | Altered Intercellular Communication | Our findings suggest a close relationship between PTSD and low-grade inflammation possibly representing one psychobiological pathway from PTSD to poor physical health, particularly with respect to cardiovascular and pulmonary disease as well as diabetes. | 19628221 |
| Diabetic Retinopathy, Inflammation | Altered Intercellular Communication | In diabetic retinopathy, the vascular endothelium is damaged due to oxidative stress and inflammation, and vitreous VEGF concentration becomes elevated. | 19628492 |
| Inflammation, Carcinoma of lung | Altered Intercellular Communication | A strong link has been recently demonstrated between inflammation and lung cancer. | 19628777 |
| Inflammation, Diabetes Mellitus, Non-Insulin-Dependent, Diabetes Mellitus | Altered Intercellular Communication | Associations between dietary fiber and inflammation, hepatic function, and risk of type 2 diabetes in older men: potential mechanisms for the benefits of fiber on diabetes risk. | 19628814 |
| Inflammation, Postoperative Complications | Altered Intercellular Communication | Data concerning pre- and postoperative visual acuity and intraocular pressure (IOP), lens status, macular status, location of primary break, surgical time, postoperative inflammation, peri- and postoperative complications, and number of sutured sites were collected. | 19629017 |
| Inflammation | Altered Intercellular Communication | We conclude that the fluctuations in the measured R wave are the result of waxing and waning inflammation associated with sarcoid activity. | 19629665 |
| Intestinal metaplasia, Gastritis, Atrophic | Altered Intercellular Communication | Elimination of H. pylori was associated with regression of gastric inflammation and atrophy, whereas intestinal metaplasia progressed. | 19629722 |
| Inflammation | Altered Intercellular Communication | However, inflammation of the gastric mucosa regresses after H. pylori elimination. | 19629722 |
| Pancreatitis, Acute, Inflammation | Altered Intercellular Communication | Patients with severe acute biliary pancreatitis (SABP) constitute a subgroup of severe acute pancreatitis (SAP) patients in whom systemic inflammation may be triggered and perpetuated by different mechanisms. | 19630953 |
| Inflammation, Osteoporosis, Atherosclerosis, Congenital Abnormality, Cardiovascular calcification | Altered Intercellular Communication | In this article, several possible mechanisms linking cardiovascular calcification and osteoporosis are discussed, including aging, tissue-specific responses to chronic inflammation, flow-limiting atherosclerosis of skeletal end arteries causing ischemic abnormalities in metabolism, shared endogenous regulatory factors that affect the two tissues in a reciprocal manner, and changes in a cysteine protease inhibitor, fetuin. | 19631027 |
| Intraocular inflammation | Altered Intercellular Communication | Primary outcome measures included suture, complication, and hypotony rates; logMAR visual acuity; and intraocular inflammation. | 19631124 |
| Inflammatory abnormality of the eye | Altered Intercellular Communication | The self-sealing incisions did not adversely affect the overall surgical or visual outcomes, led to faster visual rehabilitation, and reduced ocular inflammation. | 19631124 |
| Inflammation, Bone necrosis | Altered Intercellular Communication | Bisphosphonate-associated osteonecrosis of the jaw: a key role of inflammation? | 19631301 |
| Inflammation, Osteonecrosis of Jaw | Altered Intercellular Communication | The number of medullary inflammatory cells taken as an index of inflammation allowed us to discriminate two inflammation grades in the ONJ samples. | 19631301 |
| Inflammation, Fibrosis Assessment | Altered Intercellular Communication | Low-grade inflammation, characterized by marrow fibrosis and low inflammatory cells infiltration, increased numbers of TRAP(+) mono- and multineacleated cells was seen in patients with bone exposure<2 cm(2). | 19631301 |
| Inflammation, Leucocytic infiltrate, Arterial Hypervascularization | Altered Intercellular Communication | High-grade inflammation, associated with larger lesions, showed amounts of tartrate-resistant acid phosphatase(+)/calcitonin receptor(-) mono- and multinucleated cells, osteocyte apoptosis, hypervascularization and high inflammatory cell infiltration. | 19631301 |
| Bone necrosis | Altered Intercellular Communication | Taken together these data suggest that bone necrosis precedes clinical onset and is an inflammation-associated process. | 19631301 |
| Inflammation, Osteochondritis Dissecans | Altered Intercellular Communication | Considering that the inflammation plays a definite role in the pathogenesis of POCD and the vagus nerve can mediate inflammation via CAP, we hypothesize that the transcutaneous vagus nerve stimulation may attenuate POCD by decreasing inflammatory response in elderly patients. | 19631475 |
| Inflammation, "Alzheimers Disease", Data types - Address | Altered Intercellular Communication | Peroxisome proliferator-activated receptor gamma (PPAR-gamma) has been described to have a role in the modulation of various genes involved in Abeta homeostasis, inflammation, and energy metabolism, making it a candidate gene for risk of Alzheimer's disease (AD). | 19631630 |
| Inflammation, Vascular calcification | Altered Intercellular Communication | These included genes with roles in inflammation (IL1beta, IL8, ICAM1, TNFAP3, ESM1 and CCL2), tissue remodelling (VEGF, VEGFbeta, ADM and MMP14) and vascular calcification (MGP, BMP2, SPP1, OPG and DCN). | 19631729 |
| Autoimmune Pancreatitis | Altered Intercellular Communication | IgG4-associated cholangitis is a steroid-responsive hepatobiliary inflammatory condition associated with autoimmune pancreatitis that clinically and radiologically mimics primary sclerosing cholangitis. | 19633647 |
| Inflammation, Observation Method - Coagulation, Fibrosis Assessment | Altered Intercellular Communication | We performed real-time quantitative PCR analysis of 107 genes with functional roles in inflammation, coagulation, fibrosis and apoptosis; some key genes were confirmed at a protein expression level by immunohistochemistry and correlated to the degree of morphological severity present in the individual samples analyzed. | 19635508 |
| Inflammation, Depressed mood | Altered Intercellular Communication | Relationships between measures of inflammation and autonomic function are stronger among depressed than non-depressed cardiac patients. | 19635552 |
| Inflammation | Altered Intercellular Communication | Interventions targeting regulation of both autonomic control and inflammation may be of particular importance. | 19635552 |
| Inflammation, Crohn Disease | Altered Intercellular Communication | Mural inflammation in Crohn disease: location-matched histologic validation of MR imaging features. | 19635832 |
| Inflammation, Fibrosis Assessment, Acute inflammation, Edema | Altered Intercellular Communication | Histopathologic grading of acute inflammation with the acute inflammatory score (AIS) (on the basis of mucosal ulceration, edema, and quantity and depth of neutrophilic infiltration) and the degree of fibrostenosis was performed at each site, and results were compared with MR imaging features. | 19635832 |
| Crohn Disease | Altered Intercellular Communication | Increasing mural thickness, high mural signal intensity on T2-weighted fat-saturated images, and a layered pattern of enhancement reflect histologic features of acute small-bowel inflammation in Crohn disease. | 19635832 |
| Inflammation | Altered Intercellular Communication | A threshold brightness value of percentage of increase of 46% had a sensitivity and specificity of 96% and 73%, respectively, in the prediction of moderate or severe grade for inflammation at endoscopy. | 19635834 |
| Inflammation, Leukocytosis, Trichinellosis | Altered Intercellular Communication | Laboratory results showed mild leukocytosis, inflammation, and mild liver and muscle cytolytic syndrome, all suggestive of trichinellosis. | 19635890 |
| Inflammation, Fibrosis Assessment | Altered Intercellular Communication | Acid sphingomyelinase inhibitors normalize pulmonary ceramide and inflammation in cystic fibrosis. | 19635928 |
| Eosinophilic esophagitis | Altered Intercellular Communication | Eosinophilic esophagitis (EE) is an inflammatory condition characterized by intense eosinophilic infiltration of the esophagus. | 19636182 |
| Trachoma | Altered Intercellular Communication | In Maridi, prevalence of one of the signs of active trachoma (trachomatous inflammation-follicular (TF)) in children aged 1-9 years was 0.4% (95% confidence interval (CI), 0.0%-0.8%), while no children showing the other possible sign, trachomatous inflammation-intense (TI), were identified. | 19636366 |
| Inflammation | Altered Intercellular Communication | An urgent bronchoscopy showed two prostheses in the right and one in the left main bronchus, which had caused inflammation with extensive occlusion of the bronchus. | 19636518 |
| Tissue damage, Inflammation | Altered Intercellular Communication | Extravasation of NPLD in two patients resulted in mild inflammation without tissue damage. | 19636553 |
| concomitant disease, Endotoxemia, Colitis, Ischemic | Altered Intercellular Communication | Considering the patient's concomitant disease, we postulated that ischemic colitis with cirrhosis-related intestinal inflammation and endotoxemia was the possible diagnosis in this sporadic case. | 19636574 |
| Inflammation, Urinary tract infection | Altered Intercellular Communication | Urinary trypsin inhibitor (UTI), produced in the liver, has been considered to suppress inflammation. | 19636634 |
| Acute inflammation, Urinary tract infection | Altered Intercellular Communication | The production of UTI may decrease after a hepatectomy and thereby increase the incidence of postoperative inflammation. | 19636634 |
| Inflammation, Dilated Cardiomyopathy Pathway | Altered Intercellular Communication | Atorvastatin improves endothelial function and cardiac performance in patients with dilated cardiomyopathy: the role of inflammation. | 19636689 |
| Inflammation, Endothelium, Endothelial dysfunction | Altered Intercellular Communication | Inhibition of inflammation, alleviating endothelium damage and endothelial dysfunction might comprise part of the underlying mechanisms leading to the improvement of LV function and exercise tolerance in patients with IDCM. | 19636689 |
| Cyst, Fibrosis Assessment, Interstitial inflammation, Chronic Kidney Diseases | Altered Intercellular Communication | Affected kidneys are not only characterized by the formation of cysts, but also by changes associated with the extracellular matrix and interstitial inflammation, which can progress to fibrosis and loss of renal function. | 19637234 |
| Inflammation, Fibrosis Assessment | Altered Intercellular Communication | We confirm the development of inflammation and renal fibrosis and the expression of extracellular matrix molecules including transforming growth factor were also increased in cystic kidney. | 19637234 |
| Inflammation, Fibrosis Assessment | Altered Intercellular Communication | These results indicate that expression of proteins related with inflammation and renal fibrosis changes by Mxi1 inactivation in polycystic kidney. | 19637234 |
| Inflammation | Altered Intercellular Communication | We also measured plasma and cell-associated endotoxin and different plasma markers of inflammation. | 19638210 |
| Inflammation, Weight decreased | Altered Intercellular Communication | We are currently conducting a study to test the hypothesis that intensive weight loss will reduce inflammation and joint loads sufficiently to alter disease progression, either with or without exercise. | 19638215 |
| Traumatic, Hypopituitarism | Altered Intercellular Communication | Incomplete deficiency of hypothalamic hormones in hypothalamic hypopituitarism associated with an old traumatic brain injury. | 19638713 |
| Colorectal Carcinoma | Altered Intercellular Communication | Influence of inflammation-based prognostic score on mortality of patients undergoing chemotherapy for far advanced or recurrent unresectable colorectal cancer. | 19638907 |
| Inflammation, Edema | Altered Intercellular Communication | Thus, PRP-induced macular edema was caused by inflammation, while visual prognosis after PPV was not influenced by pretreatment of PRP. | 19639332 |
| Pain Distress Question, Neurologic Deficits, Inflammation | Altered Intercellular Communication | Clinical findings were pain due to bilateral inflammation of the lumbar nerve roots, fistulised cold abcess and motor deficit in both lower extremities. | 19639843 |
| Inflammation, Heart failure, Necrosis | Altered Intercellular Communication | Short term effects of milrinone on biomarkers of necrosis, apoptosis, and inflammation in patients with severe heart failure. | 19640280 |
| Inflammation, Myocardial Infarction | Altered Intercellular Communication | Whether biomarkers of myocardial necrosis, inflammation and apoptosis change in response to acute milrinone administration is not well established. | 19640280 |
| Inflammation, Aortic Aneurysm, Abdominal, atherosclerotic | Altered Intercellular Communication | The influence of total plasma homocysteine and traditional atherosclerotic risk factors on degree of abdominal aortic aneurysm tissue inflammation. | 19640909 |
| Aneurysm, Inflammation | Altered Intercellular Communication | Aneurysm specimens were obtained from 89 male patients aged 52 to 83 years, underwent asymptomatic not ruptured AAA (mean diameter 5.5 cm) open repair and graded for degree of histologic inflammation. | 19640909 |
| Acute respiratory failure, Inflammation | Altered Intercellular Communication | Current cigarette smoking, odds ratio (OR) 4.4, 95% confidence interval 1.3 to 15.2, P = .01 and no other ARF, neither tHcy levels OR 0.9 (0.9-1.02), P = .2 were associated with high-grade tissue inflammation. | 19640909 |
| Inflammatory abnormality of the eye, Ocular Cicatricial Pemphigoid | Altered Intercellular Communication | T-helper 17 lymphocytes (Th17) were identified in the healthy conjunctiva and in patients with ocular cicatricial pemphigoid (OCP), a disease characterized by chronic ocular surface inflammation. | 19641634 |
| Inflammation, Hypertensive (finding), Metabolic Syndrome X | Altered Intercellular Communication | Despite experimental data that demonstrates that angiotensin receptor antagonists reduce cellular oxidant stress and inflammation, olmesartan was not different than amlodipine in changing ox-NEFA and inflammatory markers in hypertensive subjects with the metabolic syndrome. | 19641984 |
| Inflammation, Conjunctivitis, Keratoconjunctivitis Sicca | Altered Intercellular Communication | After the termination of the treatment, the signs of the clinical inflammation of the conjunctival inflammation subsided but the KCS problems remained. | 19642357 |
| Inflammation, Skin Diseases, Infectious, Necrotizing fasciitis | Altered Intercellular Communication | Necrotizing fasciitis is an uncommon but serious infection of skin, subcutaneous fat and fascia, characterised by rapidly spreading inflammation and associated with considerable morbidity and mortality. | 19642531 |
| Infarction, Thrombus, Inflammation, Cerebral Atherosclerosis | Altered Intercellular Communication | In conclusion, the MCP-1 level as well as hsCRP in the blood can be a potential predictive marker of recurrent thrombotic brain infarction, and may reflect inflammation that promotes intracranial large-artery atherosclerosis. | 19642908 |
| Small bowel bacterial overgrowth syndrome, Inflammation, Intestines, Small, Affection | Altered Intercellular Communication | SIBO rate was also higher in patients with affection of both the colon and small bowel, while inflammation of the (neo)terminal ileum again showed only tendential association with the development of SIBO. | 19643023 |
| Inflammation, Respiratory Failure, Critical Illness | Altered Intercellular Communication | C-reactive protein (CRP), a biomarker of inflammation, has predicted mortality in end-stage respiratory failure and in the critically ill patients. | 19643829 |
| ARCN1 gene, Inflammation, Chronic Obstructive Airway Disease | Altered Intercellular Communication | Sputum and lung function were periodically assessed in stable moderate chronic obstructive pulmonary disease (COPD) outpatients to determine relationships between bronchial colonisation and inflammation. | 19643939 |
| ARCN1 gene, Haemophilus parainfluenzae, Conization, Bronchitis | Altered Intercellular Communication | A load-related relationship to bronchial inflammation in moderate COPD was observed for colonisation by H. influenzae, but not for colonisation by H. parainfluenzae. | 19643939 |
| Inflammation, Atherosclerosis | Altered Intercellular Communication | Peroxisome proliferator-activated receptor (PPAR) activation reduces inflammation and atherosclerosis, but recent evidence raised concerns about its beneficial clinical effects. | 19644041 |
| Inflammation, Heart failure, Carotid Intima-Media Thickness | Altered Intercellular Communication | Carotid intima-media thickness, systemic inflammation, and incidence of heart failure hospitalizations. | 19644052 |
| Inflammation, hyperthermia treatment, Ischemic stroke, Cerebrovascular accident | Altered Intercellular Communication | Severity of stroke and inflammation are important determinants of hyperthermia after ischemic stroke. | 19644066 |
| Inflammation, Electrocardiogram: myocardial infarction (finding), Cerebrovascular accident | Altered Intercellular Communication | High-sensitivity C-reactive protein (hsCRP) and lipoprotein-associated phospholipase A2 (Lp-PLA2) are hypothesized to be biomarkers of systemic inflammation and risk of myocardial infarction (MI) and stroke. | 19644070 |
| Inflammation, Phlegmonous gastritis | Altered Intercellular Communication | Gastric biopsy showed suppurative inflammation in the submucosal region, prompting the diagnosis of phlegmonous gastritis. | 19644358 |
| Idiopathic disease, Granulomatosis with polyangiitis | Altered Intercellular Communication | Wegener's granulomatosis (WG) is a rare idiopathic disease in which small and medium-sized arteries are affected by necrotizing granulomatous inflammation. | 19644426 |
| Inflammation, Kidney Failure, Acute, Fever, CTCAE | Altered Intercellular Communication | The patient developed acute renal failure, and also had fever and unilateral ear inflammation. | 19644613 |
| Refractory anemias, Inflammation, Arthritis, ASF1A gene | Altered Intercellular Communication | Gamma/delta T cells were antigen independently stimulated by inflammation at affected joints and produced enhanced amounts of IL-17 to exacerbate arthritis in mice with CIA but not in SKG mice with arthritis or patients with RA. | 19644886 |
| Inflammation, Rheumatoid Arthritis, Depression, CTCAE, Pain Distress Question | Altered Intercellular Communication | Depression, inflammation, and pain in patients with rheumatoid arthritis. | 19644894 |
| Inflammation, Depression, CTCAE | Altered Intercellular Communication | An association between depression and inflammation has been suggested. | 19644894 |
| Inflammation, Pain Distress Question, Refractory anemias, Rheumatoid Arthritis, Depression, CTCAE | Altered Intercellular Communication | In patients with rheumatoid arthritis (RA), pain is a major symptom associated with depression and inflammation. | 19644894 |
| Refractory anemias, Inflammation, Depression, CTCAE, Pain Distress Question | Altered Intercellular Communication | We examined the independent associations between depression, the inflammation marker C-reactive protein (CRP) level, and pain in patients with RA. | 19644894 |
| Inflammation, Depression, CTCAE, Pain Distress Question | Altered Intercellular Communication | Depression severity and inflammation were associated with each other and appeared to have independent effects on perceived pain. | 19644894 |
| Inflammation, Atherosclerosis | Altered Intercellular Communication | The antioxidant capacity of normal high-density lipoproteins (HDLs) is lost during inflammation, and these dysfunctional HDLs might predispose individuals to atherosclerosis. | 19644959 |
| Cardiomyopathy, Familial Idiopathic, Inflammation | Altered Intercellular Communication | These data suggest there is presence of inflammation in IDCM patients with AF. | 19645035 |
| Lesion, Inflammation | Altered Intercellular Communication | Obviously, the inflammation in AD lesions neutralizes the expected induction of hCAP18 and even induces suppression. | 19645825 |
| Airway structure, ARCN1 gene | Altered Intercellular Communication | Airway inflammation and anti-protease defences rapidly improve during treatment of an acute exacerbation of COPD. | 19645868 |
| Airway structure, ARCN1 gene | Altered Intercellular Communication | There are few data on the short-term natural history of airway inflammation during severe episodes of acute exacerbation of COPD (AECOPD). | 19645868 |
| Inflammation | Altered Intercellular Communication | Conventional treatment for severe AECOPD is associated with rapid reduction of neutrophilic inflammation and improvement in anti-protease defences. | 19645868 |
| Inflammation, Endothelial dysfunction, Diabetes Mellitus, Non-Insulin-Dependent | Altered Intercellular Communication | Current research has focused upon the potential links between novel markers of vascular risk such as endothelial dysfunction, oxidative stress, inflammation and insulin resistance in the pathogenesis of Type 2 diabetes and its complications. | 19646193 |
| Inflammation, Hypoglycemia, diabetic | Altered Intercellular Communication | GSE significantly improved markers of inflammation and glycaemia and a sole marker of oxidative stress in obese Type 2 diabetic subjects at high risk of cardiovascular events over a 4-week period, which suggests it may have a therapeutic role in decreasing cardiovascular risk. | 19646193 |
| Inflammation, Hypertensive (finding), Periodontal Diseases | Altered Intercellular Communication | The conjoint detrimental effect of chronic periodontal disease and systemic inflammation on asymmetric dimethyl-arginine in untreated hypertensive subjects. | 19646696 |
| Periodontal Diseases, Inflammation, Hypertension, CTCAE, Endothelial dysfunction | Altered Intercellular Communication | To investigate the relationship between periodontal disease indexes (PDI) and endothelial dysfunction by means of asymmetric dimethyl-arginine (ADMA) in conditions of both increased and decreased systemic inflammation in the setting of hypertension. | 19646696 |
| Inflammation, Antihypertensive Agents | Altered Intercellular Communication | PDI are associated in a dose-dependent manner with ADMA in untreated hypertensives and increased systemic inflammation further contributes to that phenomenon. | 19646696 |
| Inflammation, Diabetes Mellitus, Non-Insulin-Dependent | Altered Intercellular Communication | Impact of type 2 diabetes mellitus on diffuse inflammatory activation of de novo atheromatous lesions: implications for systemic inflammation. | 19646908 |
| Inflammation, Demographics Domain, Diabetes Mellitus | Altered Intercellular Communication | Local coronary and systemic inflammation is pronounced in patients with diabetes mellitus (DM). | 19646908 |
| Inflammation, Demographics Domain | Altered Intercellular Communication | We investigated whether or not, in patients with DM, thermal heterogeneity of culprit lesions (CLs) correlates with that of non-culprit lesions (NCLs) and with systemic inflammation. | 19646908 |
| Inflammation, Demographics Domain | Altered Intercellular Communication | In patients with DM, local inflammatory activation is diffuse and correlates with systemic inflammation. | 19646908 |
| Inflammation, Chronic Kidney Diseases | Altered Intercellular Communication | In chronic kidney disease the contribution of decreased glomerular filtration rate (GFR) versus enhanced inflammation to cause insulin resistance (IR) is controversial. | 19648735 |
| HD Term Type, Malnutrition, Inflammation | Altered Intercellular Communication | Malnutrition is common in HD patients, it is associated with inflammation and contributes to the high incidence of cardiovascular (CV) disease in this setting (malnutrition-inflammation-atherosclerosis syndrome). | 19648737 |
| Inflammation, Malnutrition | Altered Intercellular Communication | Hence, the plasma BNP level was found to be associated with malnutrition but not with inflammation. | 19648737 |
| Klinefelter Syndrome | Altered Intercellular Communication | Hormonal profile suggested primary hypogonadism and cytogenetics report suggested a karyotype, 47, XXY, in all counted cells, consistent with the diagnosis of Klinefelter syndrome. | 19651018 |
| Crohn Disease, Acute inflammation | Altered Intercellular Communication | Disordered macrophage cytokine secretion underlies impaired acute inflammation and bacterial clearance in Crohn's disease. | 19652016 |
| palladium, Psychiatry Specialty | Altered Intercellular Communication | These results provide novel in vivo evidence for a role of the cholinergic neurotransmission in psychiatric comorbidity of PD. | 19652126 |
| Inflammation, Hemorrhage, Obstruction, S100A4 protein, human | Altered Intercellular Communication | It may become clinically evident when complicated by pathological changes such as inflammation, bleeding, obstruction, and malignant transformation. | 19653355 |
| Inflammation, beta Thalassemia | Altered Intercellular Communication | Soluble endothelial adhesion molecules and inflammation markers in patients with beta-thalassemia intermedia. | 19654073 |
| Inflammation, beta Thalassemia | Altered Intercellular Communication | These findings support the hypothesis that a serious degree of endothelial activation and damage along with a state of chronic inflammation underlie the pathophysiology of beta-thalassemia intermedia. | 19654073 |
| Inflammation, Hypopyon | Altered Intercellular Communication | Significantly more severe anterior chamber inflammation in terms of anterior chamber cells (P=0.006) and hypopyon formation (P=0.034) was observed with higher frequency of AU attacks (P=0.007) in the HLA-B27 positive group than in the HLA-B27 negative group. | 19654959 |
| Unknown (origin) (qualifier value), Inflammation | Altered Intercellular Communication | In conclusion, despite more severe inflammation and a higher recurrence rate, HLA-B27 positive AU shows similar good final ocular and visual outcomes compared to HLA-B27 negative, idiopathic AU in a Korean population. | 19654959 |
| Inflammation | Altered Intercellular Communication | GCF MMP-8 levels increased with periodontal inflammation. | 19656031 |
| Inflammation, Chronic disease | Altered Intercellular Communication | Physical activity has recently been established as a potential modifier of the inflammatory process, suggesting that it mitigates inflammation and consequently reduces the incidence of several chronic diseases such as cardiovascular events. | 19657301 |
| Inflammation | Altered Intercellular Communication | These data indicate that beyond leisure time, work and transportation physical activity may reduce inflammation. | 19657301 |
| Inflammation, CD55 gene, Cerebrovascular accident | Altered Intercellular Communication | The inflammation marker Hp carried as much additional predictive information value on AMI and stroke as TC. | 19657769 |
| Inflammation, agep | Altered Intercellular Communication | Because TNF-alpha stimulated inflammation and also p53-related apoptosis occurs in AGEP, a TNF-alpha blocking agent such as etanercept may be effective for quick treatment. | 19657917 |
| Hypercalcemia, CTCAE, Inflammatory abnormality of the eye, Malignant Neoplasms | Altered Intercellular Communication | Zoledronic acid is the most effective treatment in patients with hypercalcemia secondary to malignancy; occasionally it can be related to ocular inflammation. | 19657981 |
| Choroiditis | Altered Intercellular Communication | CFs are probably a sign of severe choroidal inflammation and associated with corticosteroid resistance and/or dependence, which indicates IMT. | 19657984 |
| Inflammation | Altered Intercellular Communication | Abnormalities of ciliary structure are the cause of abnormalities in mucociliary clearance and chronic inflammation consecutively. | 19658359 |
| Ear Inflammation, Bronchiectasis, Bronchitis, Pneumonia | Altered Intercellular Communication | The boy aged 13 years with clinical manifestations (chronic rhinorrhea, sinuitis, recurrent otitis media, recurrent bronchial inflammation, pneumonia and finally bronchiectasis) has been presented. | 19658359 |
| vascular inflammations, Diabetic Angiopathies | Altered Intercellular Communication | Diabetic vascular complications are associated with vascular inflammation. | 19659775 |
| Inflammation | Altered Intercellular Communication | In all 11 specimens, immunohistochemical investigations showed a perifollicular and subepidermal inflammation of CD-3-, CD-4-, CD-68-, CD-79- and CD-8-cells, the latter with a striking selective epitheliotropism. | 19659829 |
| Phrynoderma, Inflammation, Rupture | Altered Intercellular Communication | To conclude, we could show follicular hyperkeratosis and lymphocytic perifollicular inflammation as early patterns in pathogenesis, whereas rupture of the follicle structure takes place later. | 19659829 |
| Sjogrens Syndrome", Thymic Carcinoma, Inappropriate ADH Syndrome | Altered Intercellular Communication | Thymic carcinoma associated with Sjogren's syndrome and syndrome of inappropriate antidiuretic hormone. | 19660250 |
| Inflammation, Kidney Failure, Endothelial dysfunction, Obesity | Altered Intercellular Communication | Increasing evidence suggests that both obesity and renal insufficiency are associated with increased systemic inflammation, thrombogenicity, and endothelial dysfunction. | 19660351 |
| Inflammation, Corneal edema | Altered Intercellular Communication | Anterior chamber inflammation and microhyphema, IOP, and corneal edema. | 19660735 |
| Inflammation, Cardiovascular Diseases | Altered Intercellular Communication | Minor elevations in CRP (>3 mg/L) are a nonspecific marker of systemic inflammation and predict the future onset of cardiovascular disease. | 19661186 |
| Inflammation, Drug toxicity, Necrosis | Altered Intercellular Communication | Biopsy showed sinusoidal congestion, necrosis of hepatocytes, inflammation, and hepatocyte drop out around the hepatic venule consistent with drug toxicity. | 19662540 |
| Hypoalbuminemia | Altered Intercellular Communication | Discussions whether hypoalbuminemia is just a marker for the malnutrition-inflammation syndrome as well as for the increased morbidity and mortality of those patients or is it an etiological factor, are becoming more and more intense. | 19662779 |
| Inflammation, Granulation finding | Altered Intercellular Communication | Bone trabeculae and bone units were replaced by interrupted bone fragments, which were surrounded by inflammation and granulation tissue and few osteocytes were seen in bone lacunae in the experimental group. | 19662974 |
| Inflammation, Congenital heart disease, Choline Dehydrogenase, Mitochondrial | Altered Intercellular Communication | To study the inflammation response and the biocompatibility of valved bovine jugular vein conduit (BJVC) and valved bovine jugular vein patch (VBJV-P) in treating complex congenital heart disease (CHD). | 19662998 |
| Inflammation, Atherosclerosis | Altered Intercellular Communication | Chronic immune inflammation underlying pathogenesis of PA contributes to development of early atherosclerosis and its complications. | 19663192 |
| PROS1 gene, Inflammation, Cardiovascular morbidity | Altered Intercellular Communication | Reduced HRV reflects sympatho-vagal imbalance in PsA patients associated with the disease duration and activity, smoking, femoral IMT, markers of inflammation (CRP) in males; with standard cardiovascular risk factors, fibrinogen, CRP, carotid IMT in women, and may be identified as a risk factor for cardiovascular morbidity and mortality in further studies. | 19663193 |
| Inflammation | Altered Intercellular Communication | This is closely related with the activity of systemic inflammation. | 19663195 |
| Inflammation | Altered Intercellular Communication | MMP-2 can be regarded as an important marker of inflammation as MMP-9 in the pathogenesis of AMI. | 19664397 |
| Inflammation, Whipple Disease | Altered Intercellular Communication | Reduced numbers of duodenal lymphocytes, increased numbers of CD163(+) and stabilin-1(+), reduced numbers of inducible nitric synthase+ duodenal macrophages, and increased percentages of CD163(+) peripheral monocytes indicated a lack of inflammation and a M2/alternatively activated macrophage phenotype in Whipple's disease. | 19664628 |
| Inflammation, Whipple Disease | Altered Intercellular Communication | The lack of excessive local inflammation and alternative activation of macrophages, triggered in part by the agent T whipplei itself, may explain the hallmark of Whipple's disease: invasion of the intestinal mucosa with macrophages incompetent to degrade T whipplei. | 19664628 |
| Retinal Detachment, Inflammation | Altered Intercellular Communication | Exudative retinal detachment and active intraocular inflammation were significantly associated with poorer VA in the sympathizing eye. | 19665105 |
| Retinal Detachment, Inflammation | Altered Intercellular Communication | The presence of an exudative retinal detachment and active intraocular inflammation correlated with poorer vision in the sympathizing eye. | 19665105 |
| Inflammation, Anxiety, CTCAE 3.0, Pain Distress Question | Altered Intercellular Communication | Early neonatal inflammation affects adult pain reactivity and anxiety related traits in mice: genetic background counts. | 19665540 |
| Pain Distress Question, Inflammation | Altered Intercellular Communication | Protracted or recurrent pain and inflammation in the early neonatal period may cause long-lasting changes in central neural function. | 19665540 |
| Inflammation, Anxiety, CTCAE 3.0, Pain Distress Question | Altered Intercellular Communication | (1) to study whether timing of postnatal exposure to persistent inflammation alters responsiveness to thermal pain in the adult animal; (2) to assess whether animals experiencing early postnatal chronic inflammation display altered anxiety related behavior; (3) to study the importance of genetic background. | 19665540 |
| Anxiety, CTCAE 3.0, Inflammation | Altered Intercellular Communication | Adult mice, CD1 and B6C3F1, displayed low anxiety traits only if they had been exposed to persistent inflammation on PND1 and not on PND14. | 19665540 |
| Inflammation, Pain Distress Question | Altered Intercellular Communication | Our research suggests a role for genetic background in modulating long-term behavioral consequences of neonatal persistent inflammation: the data support the hypothesis that pain experienced very early in life differentially affects adult behavioral and emotional responsiveness in outbred (CD1) and hybrid mice (B6C3F1). | 19665540 |
| Inflammation, Plaque, Atherosclerotic | Altered Intercellular Communication | Inflammation is an important element in the development and destabilization of atherosclerotic plaque. | 19665935 |
| Obesity | Altered Intercellular Communication | Obesity is considered a chronic low-grade inflammatory status and the stromal vascular fraction (SVF) cells of adipose tissue (AT) are considered a source of inflammation-related molecules. | 19666003 |
| Inflammation, Obesity | Altered Intercellular Communication | It now appears that obesity is associated with a low-grade inflammation of white adipose tissue resulting from chronic activation of the innate immune system as interleukin-1 beta (IL-1). | 19666082 |
| Acromegaly | Altered Intercellular Communication | Hormonal alterations in acromegaly stimulates adenomatose polyps development making that increase it prevalence. | 19666287 |
| Inflammation, Bile Duct Stenosis, Bile Ducts, Extrahepatic, Jaundice, Obstructive | Altered Intercellular Communication | Recurrence of inflammation in the extrahepatic bile duct can lead to bile duct stenosis, obstructive jaundice and cavernous transformation of the portal vein. | 19666415 |
| Necrosis of retina, Choroiditis | Altered Intercellular Communication | Histological examination of retinal tissue identified numerous round-to-elliptical toxoplasmic cysts within the retina, with retinal necrosis and minimal choroidal inflammation. | 19666926 |
| Primary malignant neoplasm, Toxic effect, Palmar-plantar erythrodysesthesia syndrome, Leukopenia, Inflammatory disease of mucous membrane, Thrombocytopenia | Altered Intercellular Communication | To identify genetic markers in the pharmacokinetic and pharmacodynamic pathways of sunitinib that predispose for development of toxicities: thrombocytopenia, leukopenia, mucosal inflammation, hand-foot syndrome, and any toxicity according to National Cancer Institute Common Toxicity Criteria higher than grade 2. | 19667267 |
| Inflammation, Palmar-plantar erythrodysesthesia syndrome | Altered Intercellular Communication | The risk for mucosal inflammation was increased in the presence of the G allele in CYP1A1 2455A/G (OR, 4.03; P = .021) and the prevalence of hand-foot syndrome was increased when a copy of TTT in the ABCB1 (3435C/T, 1236C/T, 2677G/T) haplotype (OR, 2.56; P = .035) was present. | 19667267 |
| Migraine Disorders, Inflammation, Cardiovascular Diseases | Altered Intercellular Communication | In migraine therapy, beta-blockers are well established as effective agents for prophylaxis, and beta-blockers may reduce levels of C-reactive protein, a sensitive marker of inflammation in cardiovascular disease. | 19667668 |
| Inflammation, Malnutrition | Altered Intercellular Communication | [Can FT3 levels facilitate the detection of inflammation or catabolism and malnutrition in dialysis patients?]. | 19668301 |
| Inflammation, Malnutrition | Altered Intercellular Communication | A reduction in thyroid function in dialysis patients could be a marker of malnutrition and/or inflammation. | 19668301 |
| Inflammation, Malnutrition, Syndrome | Altered Intercellular Communication | Our aim has been to evaluate the incidence of low T3 syndrome in a group of dialysis patients and analyze its relationship with different parameters of malnutrition and inflammation. | 19668301 |
| Inflammation, Malnutrition | Altered Intercellular Communication | Low FT3 levels are correlated bioquimical and anthropometric parameters indicators of malnutrition and inflammation. | 19668301 |
| Communicable Diseases, Inflammation, Cardiovascular Diseases | Altered Intercellular Communication | Inflammation and infection do not promote arterial aging and cardiovascular disease risk factors among lean horticulturalists. | 19668697 |
| Inflammation | Altered Intercellular Communication | Here we characterize health and aging among the Tsimane, Amazonian forager-horticulturalists with short life expectancy, high infectious loads and inflammation, but low adiposity and robust physical fitness. | 19668697 |
| Inflammation, Hypertension, CTCAE, Atherosclerosis | Altered Intercellular Communication | Inflammation has been implicated in all stages of arterial aging, atherogenesis and hypertension, and so we test whether greater inflammation associates with atherosclerosis and CVD risk. | 19668697 |
| Communicable Diseases, Inflammation | Altered Intercellular Communication | Markers of infection and inflammation were much higher among Tsimane than among U.S. adults, whereas HDL was substantially lower. | 19668697 |
| Communicable Diseases, Inflammation | Altered Intercellular Communication | Regression models examine associations of ABI and BP with biomarkers of energy balance and metabolism and of inflammation and infection. | 19668697 |
| Inflammation, Cyclophosphamide/Vincristine/Dacarbazine Regimen, Arteriovascular degeneration | Altered Intercellular Communication | Inflammation may not always be a risk factor for arterial degeneration and CVD, but instead may be offset by other factors: healthy metabolism, active lifestyle, favorable body mass, lean diet, low blood lipids and cardiorespiratory health. | 19668697 |
| Vasculitis | Altered Intercellular Communication | It is defined as inflammation of skin blood vessel walls. | 19669086 |
| Communicable Diseases, Inflammation | Altered Intercellular Communication | In group 1 inflammation occurred in 25 cases (5.3%) and an infection in 32 cases (6.8%). | 19669706 |
| Inflammation, Infection | Altered Intercellular Communication | In group 2 there were 37 cases of inflammation (5.5%) and 13 infections (2.0%). | 19669706 |
| Inflammation, Chronic Kidney Diseases | Altered Intercellular Communication | In CKD patients, TC and AVG insertion result in a transient state of inflammation 1 week post-operatively, which is not observed after AVF surgery. | 19670170 |
| Inflammation, Benign prostatic hypertrophy | Altered Intercellular Communication | Inflammation in benign prostatic hyperplasia: a 282 patients' immunohistochemical analysis. | 19670242 |
| Large prostate, Benign prostatic hypertrophy, prostatitis | Altered Intercellular Communication | Prostatic inflammation could be a key component in prostate enlargement and benign prostatic hyperplasia (BPH) progression. | 19670242 |
| Inflammation | Altered Intercellular Communication | Our aim was to characterize inflammatory cells infiltrate within BPH tissue and to correlate inflammation and clinical data. | 19670242 |
| Inflammation | Altered Intercellular Communication | Inflammation score was defined by combining six cytological parameters and five markers on immunohistochemistry (IHC). | 19670242 |
| prostatitis | Altered Intercellular Communication | IPSS score (21 vs. 12; P = 0.02) and prostate volume (77 cm(3) vs. 62 cm(3); P = 0.002) were significantly higher in patients with high-grade prostatic inflammation. | 19670242 |
| Inflammation | Altered Intercellular Communication | The role of inflammation in BPH development was highlighted by the strong correlation between histological inflammation, IPSS, and prostate volume. | 19670242 |
| Inflammation | Altered Intercellular Communication | Therefore, inflammation is a therapeutic target for BPH. | 19670242 |
| Weakness | Altered Intercellular Communication | The changes raise the possibility that TP may cause weakness through impairment of distal neural transmission. | 19670323 |
| Inflammation, Calcinosis, Coronary heart disease, Heart failure | Altered Intercellular Communication | In both groups, patients with HVC were older than HVC-free ones, more of them had coronary heart disease, cardiac insufficiency, aortic calcinosis, and biochemically identifiable inflammation. | 19670713 |
| Inflammation, Overactive Bladder | Altered Intercellular Communication | [Blood lymphocytes and mast cells of the detrusor as diagnostic markers of overactive urinary bladder and its immune inflammation]. | 19670813 |
| Inflammation, Respiratory failure without hypercapnia | Altered Intercellular Communication | Comparison of two non-bronchoscopic methods for evaluating inflammation in patients with acute hypoxaemic respiratory failure. | 19671148 |
| Pneumonitis, Respiratory failure without hypercapnia | Altered Intercellular Communication | However, there are no data comparing non-bronchoscopic bronchoalveolar lavage (mini-BAL) and s-Cath for assessing lung inflammation in acute hypoxaemic respiratory failure. | 19671148 |
| Inflammation | Altered Intercellular Communication | When the protein concentration in the lung was high, the s-Cath was a more sensitive method; by contrast, as inflammation increased, both methods provided similar estimates of neutrophil percentages in the lung. | 19671148 |
| Inflammation, Opportunistic Infections, Lesion of cervix, Cervical Intraepithelial Neoplasia | Altered Intercellular Communication | Cervical exfoliated cell specimens were collected from 301 randomly selected women accepting opportunistic screening for cervical lesions with the cytological results and hybrid capture 2 (HC-2) assay>or=atypical squamous cells of uncertain significance (ASC-US), 48 with the pathological diagnosis>or=cervical intraepithelial neoplasia (CIN)2 (case group) and 253 with normal histological result or only inflammation (control group), aged (34+/-9) (21-59). | 19671291 |
| Inflammation, Coronary Arteriosclerosis | Altered Intercellular Communication | These results indicate that high s-7KCHO is closely associated with the progression of coronary atherosclerosis and inflammation. | 19672027 |
| Inflammation, Gangrene, Appendix Perforation, CTCAE | Altered Intercellular Communication | PCT is potentially increased in rare cases of severe inflammation and, in particular, after appendiceal perforation or gangrenous appendicitis. | 19672084 |
| Inflammation, Comorbidity | Altered Intercellular Communication | Predictive characteristics included: age, sex, Charlson comorbidity score, biliary tract inflammation, hospital teaching status, and admission type. | 19672665 |
| Inflammation, Tropical Disease | Altered Intercellular Communication | A corneal penetration secondary to inflammation or chronic trophic disease is an emergency situation in ophthalmology. | 19672808 |
| Vitritis, Inflammation | Altered Intercellular Communication | After reduction of systemic drugs, the exacerbation of local inflammation and vitritis was observed. | 19673441 |
| Inflammation, Wheezing | Altered Intercellular Communication | Polymorphisms in inflammation genes, tobacco smoke and furred pets and wheeze in children. | 19674346 |
| Airway structure | Altered Intercellular Communication | Persistent wheeze in childhood is associated with airway inflammation. | 19674346 |
| Inflammation, Wheezing | Altered Intercellular Communication | Polymorphisms in inflammation genes might affect the association between environmental exposures and risk of recurrent wheeze in early childhood. | 19674346 |
| Granulomatous inflammation | Altered Intercellular Communication | Three histopathologic patterns were discovered: granulomatous inflammation (2 cases), plasma cell-rich pyogenic granuloma-like pattern (1 case), and reactive fibroinflammatory pattern (6 cases). | 19674728 |
| Inflammation, Inflammatory abnormality of the eye | Altered Intercellular Communication | Acyclovir caused a dramatic improvement in the chronic or recurrent ocular inflammation in all instances, with an average duration of improvement of inflammation of 15.3 months. | 19674728 |
| Inflammation | Altered Intercellular Communication | Non-infected hemodialysis catheters are associated with increased inflammation compared to arteriovenous fistulas. | 19675528 |
| Communicable Diseases, Inflammation | Altered Intercellular Communication | Although hemodialysis catheters predispose to infection which, in turn, causes inflammation, we studied whether they induce inflammation independent of infection. | 19675528 |
| Communicable Diseases, Inflammation | Altered Intercellular Communication | Our study shows that catheters might contribute to increased inflammation independent of infection, and supports avoidance of catheters and a timely conversion to fistulas with catheter removal. | 19675528 |
| diabetic | Altered Intercellular Communication | Hormonal environment of diabetic patients is believed to be an important contributing factor in this regard. | 19676082 |
| Inflammation, Tooth structure | Altered Intercellular Communication | A 24-month recall showed no evidence of periodontal inflammation and no adverse symptoms, and the treated tooth exhibited good healing and normal function. | 19678457 |
| Refractory anemias, Inflammation, destruction joint | Altered Intercellular Communication | Altered or chronic activation of proto-oncogenic Ras family GTPases is thought to contribute to inflammation and joint destruction in RA, and abrogation of Ras family signaling is therapeutic in animal models of RA. | 19678938 |
| Inflammation, Gastrointestinal Stromal Sarcoma | Altered Intercellular Communication | The molecular and cellular mechanisms linking chronic inflammation and gastrointestinal malignancy are not known with certainty. | 19679052 |
| Inflammation, Aortic valve disorder, Endothelial dysfunction, Atherosclerosis | Altered Intercellular Communication | The assumption that the pathogenesis of aortic valve disease is similar to that of atherosclerosis has not been supported by recent studies; rather there has been increasing evidence of a pathogenetic role of inflammation and endothelial dysfunction. | 19679278 |
| Communicable Diseases, Necrotizing vasculitis, Inflammation, Meningovascular syphilis | Altered Intercellular Communication | Laboratory findings were suggestive of prior spirochetal infection, and autopsy revealed necrotizing vasculitis and extensive adventitial inflammation involving the basilar and vertebral arteries, supporting the diagnosis of meningovascular syphilis. | 19680027 |
| Inflammation, Uveitis | Altered Intercellular Communication | The preoperative complications resolved in all cases, with the inflammation settling postoperatively in the patients with preoperative uveitis and no patients developing tube or plate exposure at last follow-up. | 19680058 |
| Demyelination, Multiple Sclerosis, Meningitis | Altered Intercellular Communication | Meningeal inflammation is not associated with cortical demyelination in chronic multiple sclerosis. | 19680141 |
| Meningitis | Altered Intercellular Communication | Quantitative analysis revealed significant meningeal inflammation in chronic MS patients; T cells were the predominant inflammatory cells. | 19680141 |
| Demyelination, Meningitis | Altered Intercellular Communication | Morphometric analysis was performed on coronal hemisphere sections of the MS cases to assess subpial demyelination; no correlation between the extent of subpial demyelination and extent of meningeal inflammation was identified. | 19680141 |
| Meningitis | Altered Intercellular Communication | Our data suggest that the occurrence of cortical lesions is not related to the presence of meningeal inflammation in a large number of chronic MS patients. | 19680141 |
| Obesity | Altered Intercellular Communication | These results provide evidences of an existing relationship between HVEM and obesity, which suggest that this TNF superfamily receptor could be involved in the pathogenesis of obesity and inflammation-related activity. | 19680232 |
| Keratitis | Altered Intercellular Communication | In two patients with initial graft rejection and vascularization, subconjunctival and perilimbal application of bevacizumab was beneficial in overcoming the corneal inflammation and initial rejection. | 19680676 |
| Inflammation, Obesity | Altered Intercellular Communication | Although it is produced mainly in the liver, its recently described expression in adipose tissue has been shown to be enhanced in massive obesity due to chronic low-grade inflammation. | 19681654 |
| hepcidin | Altered Intercellular Communication | We suggest that acute inflammatory changes could affect the regulation of hepcidin expression in subcutaneous adipose tissue and thus possibly contribute to inflammation-induced systemic changes of iron metabolism. | 19681654 |
| Cholestasis, Pruritus, Fatigue | Altered Intercellular Communication | Some studies suggest that certain clinical symptoms of cholestasis, such as fatigue and pruritus, result from altered neurotransmission. | 19681778 |
| Respiration Disorders, IgE-mediated food allergy, Inflammatory disease of mucous membrane | Altered Intercellular Communication | The pathology underlying allergic respiratory diseases is considered to be IgE-mediated type I allergy characterized by mucosal inflammation that occurs in response to allergen exposure. | 19681921 |
| Follicle, Inflammation, Communicable Diseases | Altered Intercellular Communication | The primary event is a follicular occlusion with secondary inflammation, infection and destruction of the pilo-sebaceo-apocrine apparatus and extension to the adjacent sub-cutaneous tissue. | 19682181 |
| Cessation of life, Inflammation, incident | Altered Intercellular Communication | Circulating biomarkers of inflammation and hemostasis are associated with incident MI/CHD death but not incident angina uncomplicated by MI or CHD death in older men. | 19682232 |
| Inflammation, Hyperhomocysteinemia | Altered Intercellular Communication | Matrix degradation and inflammation may be involved in this link between hyperhomocysteinaemia and CVD. | 19682403 |
| Inflammation, Thrombosis | Altered Intercellular Communication | Inflammation and thrombosis biomarkers and incident frailty in postmenopausal women. | 19682668 |
| methyldopa, Age related macular degeneration | Altered Intercellular Communication | Inflammation probably plays a major role in the pathogenesis of age-related macular degeneration (AMD). | 19684010 |
| Inflammation | Altered Intercellular Communication | In GCA and chronic inflammation most monocytes and lymphocytes expressed GR (88.9%). | 19684157 |
| Inflammation | Altered Intercellular Communication | The presence of CD68-positive cells and the extent of GR-staining in chronic inflammation are suitable to predict complete remission in GCA. | 19684157 |
| Rheumatoid Arthritis, Temporomandibular Joint | Altered Intercellular Communication | Endogenous glutamate in association with inflammatory and hormonal factors modulates bone tissue resorption of the temporomandibular joint in patients with early rheumatoid arthritis. | 19686927 |
| Inflammation, Observation Method - Coagulation | Altered Intercellular Communication | Associations of long- and short-term air pollution exposure with markers of inflammation and coagulation in a population sample. | 19687019 |
| Orthodontic, Inflammation | Altered Intercellular Communication | Insertion of fixed orthodontic appliances can induce an increase in oral biofilm and thereby cause inflammation of the periodontal tissues. | 19687149 |
| Inflammation | Altered Intercellular Communication | Panniculitides encompass various clinical syndromes characterized by inflammation of the fibrous septae, fatty lobules, or both components of the subcutaneous tissue. | 19687423 |
| Inflammation, Narcolepsy | Altered Intercellular Communication | To test this hypothesis, we evaluated the remaining hypocretin cells in human narcolepsy brains for the presence of aggregated protein inclusions, gliosis, and inflammation. | 19687452 |
| Inflammation | Altered Intercellular Communication | The lack of increased markers of inflammation also argues against a progressive and continuous neurodegenerative process. | 19687452 |
| Inflammation, Arthritis | Altered Intercellular Communication | Leptin is an adipokine regulating energy balance, and it has recently been related also to arthritis and inflammation as a proinflammatory factor. | 19688109 |
| Neurogenic Inflammation, Fibromyalgia, Urticaria, Neuropathy | Altered Intercellular Communication | Chronic urticaria may thus be viewed in many patients, as a consequence of fibromyalgia syndrome; in fact, skin neuropathy (fibromyalgia syndrome) may trigger neurogenic skin inflammation (chronic urticaria). | 19688152 |
| APP gene, Inflammation, Aortic Aneurysm, Abdominal, Endothelial dysfunction | Altered Intercellular Communication | The etiology of abdominal aortic aneurysm (AAA) includes inflammation and endothelial dysfunction. | 19689995 |
| Inflammation, Ototoxicity | Altered Intercellular Communication | Whereas factors responsible for disease initiation affect striatal subregions differently, those factors contributing to disease progression affect all striatal subregions to a similar degree and may therefore reflect non-specific mechanisms such as oxidative stress, inflammation or excitotoxicity. | 19690093 |
| Inflammation, Fibrosis Assessment, Fatty degeneration | Altered Intercellular Communication | In addition, liver biopsy was analyzed for steatosis, inflammation and fibrosis. | 19690397 |
| Inflammation, Fibrosis Assessment, Bronchiolitis | Altered Intercellular Communication | Compared to controls, patients with UIP, NSIP and CB presented increased bronchiolar inflammation, peribronchiolar inflammation and fibrosis and decreased luminal areas. | 19690403 |
| Orbital Pseudotumor | Altered Intercellular Communication | Idiopathic sclerosing orbital inflammation--a case series study. | 19690442 |
| Gliosis, Inflammation, Spongiosis, Necrosis, Pathologic Neovascularization | Altered Intercellular Communication | The second phase (n=14 patients) was subdivided into: (a) a phase of acute inflammation (3-37 days after onset) (n=5 patients), where we observed especially features of acute inflammation together with coagulative necrosis, and (b) phase of chronic inflammation (10 days-53 years after the onset) (n=9 patients), in which prevail mononuclear and macrophage infiltrate, astrogliosis, spongiosis and neo-vascularization. | 19690757 |
| Inflammation, Helicobacter pylori, Primary malignant neoplasm, Communicable Diseases, Ulceration, CTCAE | Altered Intercellular Communication | Helicobacter pylori (H. pylori) infection up-regulates the expression of matrix metalloproteinases (MMPs), which may be involved in chronic inflammation, ulceration, and even cancer development. | 19690958 |
| Inflammation, Fibrosis Assessment, Weight decreased, Fatty degeneration | Altered Intercellular Communication | The combination of weight loss and antioxidant drugs to ameliorate insulin resistance and improve steatosis, inflammation and fibrosis provides the rational for therapeutic trials. | 19691668 |
| Inflammation, Fibrosis Assessment, Fatty degeneration | Altered Intercellular Communication | On between-group comparison, Viusid was found to be associated with a significantly greater improvement in steatosis (P < 0.001), ballooning (P = 0.002) and lobular inflammation (P = 0.025), but not in fibrosis (P = 0.07). | 19691668 |
| Inflammation, Non-alcoholic Fatty Liver Disease, Fatty degeneration | Altered Intercellular Communication | Our results indicate that treatment with diet and exercise leads to a notable improvement in the histological features of NAFLD; however, the administration of Viusid intensifies the improvements of histological findings, especially of steatosis and inflammation. | 19691668 |
| Inflammation, Helicobacter pylori | Altered Intercellular Communication | Histological examinations of biopsy specimens taken from the giant folds showed signs of chronic inflammation, and Helicobacter pylori was also identified. | 19691800 |
| HD Term Type, Inflammation, Overhydration | Altered Intercellular Communication | Inflammation, overhydration and elevated cardiac biomarkers are related to outcome in haemodialysis (HD) patients. | 19692417 |
| HD Term Type, Inflammation | Altered Intercellular Communication | Here, we explored the relationship between the body composition (BC), inflammation and cardiac biomarker concentrations in HD patients longitudinally. | 19692417 |
| Inflammation, Malnutrition, Overhydration | Altered Intercellular Communication | Moreover, cTnT, BNP, NT-proBNP and hsCRP were significantly related, showing a complex relation between overhydration, malnutrition, inflammation and cardiac biomarkers in dialysis patients. | 19692417 |
| Inflammation, Rhabdomyolysis | Altered Intercellular Communication | Clinical and echographic evaluations were diagnostic of pectoral inflammation suggesting rhabdomyolysis. | 19692835 |
| Inflammation, Neurocysticercosis | Altered Intercellular Communication | The association of host age and gender with inflammation around neurocysticercosis cysts. | 19695154 |
| Granuloma, Pneumonitis, Pulmonary Fibrosis | Altered Intercellular Communication | Pathological examinations of patients' lung tissue displayed nonspecific pulmonary inflammation, pulmonary fibrosis and foreign-body granulomas of pleura. | 19696157 |
| Dry Eye Syndromes, Conjunctivitis | Altered Intercellular Communication | Confocal scanning laser microscopy was an efficient and a noninvasive tool for the quantitative assessment of the conjunctival inflammation and epithelial cell densities as well as evaluation of conjunctival morphologic alterations, such as microcysts in patients with SSDE and NSSDE dry eye disease. | 19696170 |
| Inflammation, Observation Method - Coagulation | Altered Intercellular Communication | Involvement of platelet coagulation and inflammation in the endothelium of Schlemm's canal. | 19696181 |
| Inflammation, Observation Method - Coagulation | Altered Intercellular Communication | To investigate whether the endothelial cells of Schlemm's canal (ECSCs) are connected to lymphatic vessels or are involved in platelet coagulation and inflammation, by comparing them to lung tissue cells. | 19696181 |
| Inflammation | Altered Intercellular Communication | ECSCs and EACLs are suggested to have developed specifically for their functions from the aspects of the anti-platelet coagulation system and may be involved in inflammation for leukocyte infiltration. | 19696181 |
| Hashimoto Disease, Inflammation, Thyroiditis | Altered Intercellular Communication | The histologic diagnosis of lymphocytic (Hashimoto) thyroiditis requires lymphocytic inflammation of the thyroid gland in combination with Hourthle cell metaplasia of follicular epithelial cells. | 19696577 |
| Inflammation, Hurthle cell metaplasia of thyroid gland | Altered Intercellular Communication | The degree of lymphocytic inflammation of the thyroid gland was graded on a scale of 0 to 3 (0 = no inflammation, 1 = mild inflammation, 2-3 moderate-to-marked inflammation with Hourthle cell metaplasia). | 19696577 |
| Arterial Stiffness, Inflammation, Hypertension, CTCAE, Hyperuricemia | Altered Intercellular Communication | It is suggested that the combination of olmesartan and azelnidipine has advantages over the combination of olmesartan and a thiazide with respect to avoiding hyperuricemia, sympathetic activation, renin-angiotensin-aldosterone system stimulation, inflammation, oxidative stress, and increased arterial stiffness in patients with moderate hypertension. | 19696778 |
| Inflammation | Altered Intercellular Communication | Acute inflammation in horizontal incompletely impacted third molar with radiolucency in the elderly. | 19696898 |
| Inflammation | Altered Intercellular Communication | The odds ratio of severe acute inflammation exhibited in men aged more than 61 years compared to men aged 41-50 years was 16.67 (95% CI: 1.76-158.27; P < 0.01). | 19696898 |
| Inflammation | Altered Intercellular Communication | These odds ratios indicate an association of acute pericoronitis, including the severe forms of acute inflammation that result from pericoronitis, with pericoronal radiolucency below the crown in the elderly. | 19696898 |
| Nonalcoholic Steatohepatitis, Inflammation, Fibrosis Assessment, Fatty degeneration, Non-alcoholic Fatty Liver Disease, Balloon Dilatation, Fatty Liver Disease | Altered Intercellular Communication | NAFLD was classified as simple steatosis, type 1 nonalcoholic steatohepatitis (NASH), characterized by ballooning degeneration and perisinusoidal fibrosis, or type 2 NASH, characterized by portal inflammation and portal fibrosis. | 19697129 |
| Thrombosis | Altered Intercellular Communication | The white blood cell count and its differential are established inflammation-sensitive biomarkers with a proven prognostic value in the field of atherothrombosis. | 19697588 |
| Necrotizing granulomatous inflammation, Adenolymphoma, Facial paralysis | Altered Intercellular Communication | Fine needle aspiration cytology and diagnostic pitfalls in Warthin's tumor with necrotizing granulomatous inflammation and facial nerve paralysis: a case report. | 19697730 |
| Inflammation, Necrosis | Altered Intercellular Communication | Cytologic examination showed acute, chronic and granulomatous inflammation and rare squamous cells in a background of finely granular necrotic debris. | 19697730 |
| Necrotizing granulomatous inflammation, Inflammation, Fibrosis Assessment, Squamous metaplasia | Altered Intercellular Communication | Histologic examination of the excised mass revealed a WT with extensive necrotizing granulomatous inflammation, with acute and chronic inflammation, fibrosis and squamous metaplasia. | 19697730 |
| Inflammation, "Alzheimers Disease", Data types - Address | Altered Intercellular Communication | Chronic inflammation is a characteristic of Alzheimer's disease (AD). | 19698145 |
| Inflammation, Data types - Address | Altered Intercellular Communication | Thus, inflammation facilitates the onset of sporadic AD. | 19698145 |
| HD Term Type, Inflammation | Altered Intercellular Communication | Increased sCD14 level is related positively to markers of inflammation and negatively to nutritional status and is an independent predictor of mortality in long-term HD patients. | 19699018 |
| vascular inflammations | Altered Intercellular Communication | Specifically, markers of vascular inflammation and oxidative stress might be helpful in the determination of clinical outcomes. | 19699337 |
| Inflammation, Atherosclerosis | Altered Intercellular Communication | Our study results demonstrated that neutrophils and monocytes which play an important role in inflammation and atherosclerosis were independently related with SUA. | 19699626 |
| Inflammation | Altered Intercellular Communication | There was no relationship between sACE2 activity and markers of systemic inflammation. | 19700132 |
| Inflammation | Altered Intercellular Communication | Secondhand smoke (SHS) exposure is associated with circulating markers of inflammation and endothelial function in adult men and women. | 19700161 |
| Intraocular inflammation | Altered Intercellular Communication | There were no serious adverse events and no identifiable intraocular inflammation. | 19700196 |
| Inflammatory abnormality of the eye | Altered Intercellular Communication | Intravitreal injection of up to 4 mg of VEGF Trap-Eye in patients with NVAMD was well tolerated with no evidence of ocular inflammation. | 19700196 |
| Acute Lung Injury, Inflammation, Observation Method - Coagulation, Disease | Altered Intercellular Communication | Coagulation and fibrinolysis abnormalities are observed in acute lung injury (ALI) in both human disease and animal models and may contribute to ongoing inflammation in the lung. | 19700643 |
| Inflammation, Lung cyst | Altered Intercellular Communication | The triterpenoid CDDO limits inflammation in preclinical models of cystic fibrosis lung disease. | 19700644 |
| Inflammation, Fibrosis Assessment, Lung | Altered Intercellular Communication | Excessive inflammation in cystic fibrosis (CF) lung disease is a contributor to progressive pulmonary decline. | 19700644 |
| Obesity Hypoventilation Syndrome, Inflammation, Endothelial dysfunction | Altered Intercellular Communication | Endothelial dysfunction and specific inflammation in obesity hypoventilation syndrome. | 19701463 |
| Hypoventilation, Inflammation, Endothelial dysfunction, Obesity | Altered Intercellular Communication | What moderate chronic hypoventilation adds to obesity on systemic inflammation and endothelial dysfunction remains unknown. | 19701463 |
| Intraocular inflammation, Retinal Vasculitis | Altered Intercellular Communication | Multiple yellowish spots appeared in the deep retina without evidence of intraocular inflammation or retinal vasculitis. | 19702067 |
| Traumatic injury, Fibromatosis, Aggressive | Altered Intercellular Communication | The etiology of desmoid tumors are uncertain but may be related to operation, trauma or hormonal factors. | 19702071 |
| Intraocular inflammation | Altered Intercellular Communication | Frequency and clinical features of intraocular inflammation in Tokyo. | 19702710 |
| Intraocular inflammation, Uveitis | Altered Intercellular Communication | To investigate frequencies and clinical features of intraocular inflammation (uveitis) in Tokyo, Japan. | 19702710 |
| Communicable Diseases | Altered Intercellular Communication | It is important for emergency physicians to be aware of the classic and most common risk factors leading to this illness, including genetic and acquired prothrombotic states, infection, inflammatory conditions, and certain drugs. | 19703742 |
| Inflammation | Altered Intercellular Communication | We have recently described a novel population of natural regulatory T cells (T(reg)) that are characterized by the expression of HLA-G and may be found at sites of tissue inflammation (HLA-G(pos) T(reg)). | 19705413 |
| Inflammation, Hemorrhage | Altered Intercellular Communication | Maximal bladder capacity was negatively correlated with inflammation, mast cell count, haemorrhages and the overall cystoscopic aspect. | 19707951 |
| Inflammatory Bowel Diseases, Crohn Disease, Inflammation | Altered Intercellular Communication | Crohn's disease is a chronic inflammatory bowel disease characterized by discontinuous chronic inflammation that may affect virtually all organs, including the head and neck. | 19708494 |
| Inflammation, Ischemic stroke | Altered Intercellular Communication | Accumulating evidence suggests that inflammation plays an important role in the acute phase of ischemic stroke. | 19709661 |
| Inflammation, Fibrosis Assessment, Edema | Altered Intercellular Communication | CMR markers for oedema, inflammation and fibrosis defined myocardial involvement. | 19710029 |
| Inflammation, Fibrosis Assessment | Altered Intercellular Communication | Early enhancement images were quantified for inflammation, as was regional fibrosis in late enhancement images. | 19710029 |
| Inflammation, Atrophic | Altered Intercellular Communication | A histological analysis showed that cagA status was associated with inflammation and atrophy both in the antrum and in the corpus, while homB status was associated with inflammation and atrophy in the corpus. | 19710266 |
| helium, Hepatic Encephalopathy, Abnormal behavior, Chronic liver disease | Altered Intercellular Communication | Hepatic encephalopathy (HE) in chronic liver disease is characterized by neuropsychiatric and motor disturbances and associated with a net increase of inhibitory neurotransmission. | 19710544 |
| helium, Abnormal behavior | Altered Intercellular Communication | Our data suggest that neurotransmitter alterations are probably not the primary key factor responsible for the neuropsychiatric and motor disturbances associated with HE. | 19710544 |
| Inflammation, Fibrosis Assessment, MULTISYSTEM DISORDER | Altered Intercellular Communication | Cystic fibrosis (CF) is a multisystem disorder intrinsically associated with inflammation of mucosal surfaces. | 19710558 |
| Inflammation, Ileal Obstruction, distal ileal obstruction syndrome, Ileitis, neuromuscular function | Altered Intercellular Communication | Because inflammation can result in enteric neuromuscular dysfunction we hypothesized that terminal ileitis in patients with CF may predispose to distal ileal obstruction syndrome (DIOS). | 19710558 |
| Inflammation, distal ileal obstruction syndrome | Altered Intercellular Communication | Lymphocyte-predominant mucosal and transmural ileal inflammation was present in 6 of 6 patients with DIOS. | 19710558 |
| Inflammation | Altered Intercellular Communication | Submucosal or transmural lymphocyte predominant inflammation was also present in 6 of 6 infants with complicated MI, which, when coupled with submucosal myofibroblast proliferation (5/6), appeared highly predictive of CF rather than non-CF atresia. | 19710558 |
| Inflammation, distal ileal obstruction syndrome | Altered Intercellular Communication | Submucosal or transmural inflammation of the ileum is common in newborns with CF and MI and older children with DIOS. | 19710558 |
| Pain Distress Question, Inflammation, Blepharoptosis | Altered Intercellular Communication | A nine-year-old girl presented with pain, unilateral ptosis, inflammation of the upper eyelid and restricted ocular motility. | 19710967 |
| Inflammation | Altered Intercellular Communication | Three years after salmonellosis, PI-FGID patients showed no evidence of inflammation in the gastric or colonic mucosa, but visceral sensitivity and anxiety/somatization levels were increased. | 19711225 |
| Esophagitis | Altered Intercellular Communication | The eosinophilic oesophagitis is a rare allergy-like inflammation of the oesophagus especially seen in young men with increasing incidence. | 19711290 |
| Inflammation, Dysplasia | Altered Intercellular Communication | The feasibility of autofluorescence spectroscopy to detect subtle alterations in tissue architecture and biochemical composition induced by dysplasia and inflammation has been studied in the field of oral oncology. | 19712020 |
| Inflammation, Kidney Failure, Cardiovascular Diseases | Altered Intercellular Communication | Further studies are needed to test other genetic determinants of the association between systemic inflammation and cardiovascular disease in renal failure patients. | 19712260 |
| Pituitary Adenoma, Pituitary Diseases, Hyperprolactinemia | Altered Intercellular Communication | Magnetic resonance imaging revealed a pituitary adenoma, and laboratory tests corroborated the hyperprolactinaemia without other hormonal pituitary abnormalities. | 19712547 |
| vascular inflammations, Thrombosis | Altered Intercellular Communication | Our findings showed that the Mediterranean diet influences expression of key genes involved in vascular inflammation, foam cell formation and thrombosis. | 19712933 |
| Inflammation, Calcinosis, Cardiac Hypertrophy | Altered Intercellular Communication | Patients with all three calcification risk factors, namely inflammation, high CaxP, and no RRF, showed the highest prevalence of valvular calcification and had the most severe cardiac hypertrophy. | 19713292 |
| palladium, Cardiac Hypertrophy, Inflammation | Altered Intercellular Communication | The association among loss of RRF, valvular calcification, and cardiac hypertrophy was closely linked to increased inflammation and high Ca x P in PD patients. | 19713292 |
| Inflammation, AAVS1 gene, Vasculitis, CTCAE, Disease remission | Altered Intercellular Communication | Numbers of circulating CD4+ effector memory T cells are proportionally increased in patients with proteinase 3 antineutrophil cytoplasmic antibody-associated vasculitis (AAV) whose disease is in remission and are decreased during active disease, which presumably reflects their migration toward sites of inflammation. | 19714581 |
| Inflammation | Altered Intercellular Communication | Moreover, a negative correlation was observed between percentages of circulating and urine CD4+ effector memory T cells, consistent with their migration toward sites of inflammation. | 19714581 |
| Refractory anemias, Inflammation | Altered Intercellular Communication | Our data suggest that enhanced expression of IL-7Ralpha and IL-7 in RA patients contributes significantly to the joint inflammation by activating T cells, B cells, and macrophages. | 19714586 |
| Inflammatory, Inflammation, Spondylitis | Altered Intercellular Communication | Magnetic resonance imaging assessment of spinal inflammation in ankylosing spondylitis: standard clinical protocols may omit inflammatory lesions in thoracic vertebrae. | 19714609 |
| Inflammation, Spondylitis | Altered Intercellular Communication | Radiologic assessment of spinal inflammation in patients with ankylosing spondylitis (AS) relies primarily on magnetic resonance imaging (MRI), although little is known about the distribution of inflammatory lesions within the structures of the spine. | 19714609 |
| Inflammation | Altered Intercellular Communication | Inflammation was present in 263 (45%) of 588 thoracic and 86 (35%) of 245 lumbar vertebrae; the mean number of affected thoracic and lumbar vertebrae per patient were 5.4 and 1.8, respectively. | 19714609 |
| Inflammation | Altered Intercellular Communication | Inflammation was present in the lateral aspect of 219 (37%) of 588 thoracic vertebrae and 45 (18%) of 245 lumbar vertebrae (P < 0.001). | 19714609 |
| Gastrointestinal inflammation, Ulcerative Colitis | Altered Intercellular Communication | These findings further indicate potential regulatory functions of adipokines in intestinal inflammation that are partly gender-dependent and that may even be associated with the distinct immunopathogenesis of UC and CD. | 19714754 |
| Asthma | Altered Intercellular Communication | Depletion of antioxidants through consumption of a low antioxidant diet has been reported to increase neutrophilic airway inflammation and worsen symptoms of asthma. | 19715394 |
| Inflammation, Diabetes Mellitus | Altered Intercellular Communication | Greater posttransplant inflammation and oxidation are associated with worsening kidney function in patients with pretransplant diabetes mellitus. | 19715851 |
| Inflammation | Altered Intercellular Communication | Patients on dialysis display increased inflammation (IF) and oxidative stress (OS). | 19715851 |
| Inflammation, Atherosclerosis | Altered Intercellular Communication | At present, inflammation is considered to be one of the key players in the development and maintenance of atherosclerosis, with ample impact on renal transplant outcomes. | 19715970 |
| Inflammation, Pulmonary Embolism, pulmonary edema interstitial, Pulmonary Emphysema, Lung Diseases, Interstitial, Embolism, Infectious Lung Disorder | Altered Intercellular Communication | Type B (18 cases) occurred in pulmonary embolism; type C was found in case of inflammation of small respiratory airways (five cases); emphysema was typical for type D (nine cases); increased perfusion was observed in the parenchyma preserved from emphysema or preserved from embolism in cases of emphysema or pulmonary embolism; type F occurred in pulmonary interstitial edema (four cases) both with pulmonary infection; finally type G was found in interstitial lung diseases (five cases). | 19717260 |
| Inflammation, Endothelial dysfunction, diabetic, Atherosclerosis | Altered Intercellular Communication | Endothelial dysfunction is a common feature in type-2 diabetic patients and is associated with inflammation, increased levels of circulating soluble adhesion molecules and atherosclerosis. | 19717975 |
| Inflammation, Mental deterioration | Altered Intercellular Communication | Intensive oral hygiene care can persistently improve oral inflammation status and could slow periodontal deterioration. | 19718402 |
| Inflammation, Acute chest pain | Altered Intercellular Communication | PTX3 is a new biomarker related to inflammation that, independently of BNP, strongly predicts long-term all-cause mortality in patients with acute chest pain. | 19718477 |
| Inflammation, Idiopathic Pulmonary Fibrosis, Pneumonia, Idiopathic Interstitial Pneumonias, Fibrosis Assessment, CARD16 gene, Nonspecific interstitial pneumonia, Pneumonia, Interstitial | Altered Intercellular Communication | Idiopathic interstitial pneumonias (IIPs) comprises a group of diffuse parenchymal lung diseases of unknown etiology with varying degrees of inflammation and fibrosis including cryptogenic organizing pneumonia (COP), idiopathic pulmonary fibrosis (IPF) and nonspecific interstitial pneumonia (NSIP). | 19721293 |
| Inflammation, Idiopathic Interstitial Pneumonias | Altered Intercellular Communication | Systemic inflammation in the lung with IIPs might be associated with tenascin-C. | 19721293 |
| Inflammation, Idiopathic Interstitial Pneumonias | Altered Intercellular Communication | These results suggest that tenascin-C is responsible for the pathogenesis of IIPs especially via inflammation, and that it might serve as a serum marker of COP. | 19721293 |
| Inflammation, Retinitis Pigmentosa, polychondritis, Systemic disease | Altered Intercellular Communication | Relapsing polychondritis (RP) is a rare multisystemic disease characterized by the recurrent inflammation of the cartilaginous structures of the external ear, nose, joint, larynx, and tracheobronchial tree, whose etiology might involve an immunological mechanism. | 19721348 |
| Tuberculosis | Altered Intercellular Communication | [Tubercular inflammation of cervical lymph nodes with a colliquative tuberculosis focus--a case study]. | 19722149 |
| Gingivitis | Altered Intercellular Communication | However, its presence during the pathogenesis of gingival inflammation has not been established in vivo. | 19722795 |
| Inflammation | Altered Intercellular Communication | Depleted tissue concentrations of Ang-1 may allow gingival inflammation to become more severe because VEGF and ET-1 secretion become less inhibited. | 19722795 |
| Inflammation, Alveolar Bone Loss | Altered Intercellular Communication | A 12-year-old child was referred to our clinic for gingival inflammation, extensive alveolar bone loss, and tooth mobility. | 19722808 |
| Parkinson Disease, Inflammation, palladium | Altered Intercellular Communication | The protein identities reflect the heterogeneity of Parkinson's disease, and thus may provide the capability of monitoring the blood for a diverse range of PD pathophysiological mechanisms: cellular degeneration, oxidative stress, inflammation, and transport. | 19723509 |
| Inflammation, Obesity, muscle mass | Altered Intercellular Communication | How obesity, muscle mass, inflammation, hormonal and lipid status, oxidative stress, antioxidant capacity and physical activity influences insulin sensitivity (IS) in frail elderly subjects remains uncertain. | 19723576 |
| Inflammation, Obesity, muscle mass | Altered Intercellular Communication | How obesity, muscle mass, inflammation, hormonal and lipid status, oxidative stress, antioxidant capacity and physical activity influences insulin sensitivity (IS) in frail elderly subjects remains uncertain. | 19723576 |
| Cessation of life, Inflammation | Altered Intercellular Communication | Age, male sex, markers of inflammation, and cognitive function were related to multiple causes of death. | 19723772 |
| Cessation of life, Inflammation | Altered Intercellular Communication | Inflammation may represent a common pathway to all causes of death. | 19723772 |
| Inflammation, Endophthalmitis, CTCAE, Glaucoma, CTCAE | Altered Intercellular Communication | Complications can occur and require frequent follow-up to monitor and treat glaucoma progression, endophthalmitis, and inflammation. | 19724214 |
| Inflammation, Dysplasia | Altered Intercellular Communication | In fact, long-standing inflammation could be directly responsible for the development of pancellular dysplasia involving epithelial, goblet, Paneth and neuroendocrine cells. | 19725156 |
| Inflammation, prostatitis | Altered Intercellular Communication | Aggressiveness of inflammation in histological prostatitis--correlation with total and free prostate specific antigen levels in men with biochemical criteria for prostate biopsy. | 19725275 |
| Inflammation, prostatitis | Altered Intercellular Communication | Although prostatitis can contribute to the lack of prostate specific antigen (tPSA) specificity, there is disagreement concerning the effect of histological inflammation on free PSA (fPSA). | 19725275 |
| Inflammation, Aggressive behavior, Prostate carcinoma | Altered Intercellular Communication | We investigated the correlation between aggressiveness of histological inflammation and tPSA, fPSA and f/tPSA in patients without detectable prostate cancer (PC). | 19725275 |
| Inflammation, Fibrosis Assessment, Stenosis, Leakage of bile | Altered Intercellular Communication | The axial nature of the blood supply to the extrahepatic ducts and the tendency of bile itself to cause rapid collagen turnover and fibrosis, combined with the inflammation and subsequent fibrosis to the surrounding tissues caused by bile leakage, give the bile ducts a high propensity for stricture formation. | 19725297 |
| Liver Abscess, Inflammation, Hepatic Infarction, Neoplasms | Altered Intercellular Communication | Microscopically, the tumor consisted of hepatic infarction, degenerated Glisson's sheath, and chronic inflammation, and chronic liver abscess was diagnosed. | 19725434 |
| Inflammation, Biceps tendinitis | Altered Intercellular Communication | Biceps tendinitis is inflammation of the tendon around the long head of the biceps muscle. | 19725488 |
| Biceps tendinitis | Altered Intercellular Communication | Inflammation of the biceps tendon in the bicipital groove, which is known as primary biceps tendinitis, occurs in 5 percent of patients with biceps tendinitis. | 19725488 |
| Cataract, Inflammation, Retinal thickening | Altered Intercellular Communication | BF suppressed anterior chamber inflammation and increasing retinal thickening after cataract surgery in patients with NPDR. | 19725815 |
| Granulomatous inflammation | Altered Intercellular Communication | Subsequent open lung biopsy revealed marked granulomatous inflammation with diagnostic Reed-Sternberg cells. | 19727013 |
| Inflammation, Neoplasms | Altered Intercellular Communication | Secondary endpoints were change in cleaved caspase-3 (CC3, apoptosis), MRI tumor volume, and serum C-reactive protein (CRP, inflammation). | 19728082 |
| Inflammation | Altered Intercellular Communication | This may be caused by a consecutive therapy associated inflammation. | 19728194 |
| Airway structure | Altered Intercellular Communication | Vitamin A and carotenoids are dietary antioxidants that are likely to play an important role against airway inflammation. | 19728208 |
| Hemorrhagic, Inflammation, Papilledema | Altered Intercellular Communication | Other frequent findings at the back of the eye are hemorrhagic nerve fibers, cotton-like exudates, papilla edema, macular star and glassy inflammation. | 19728239 |
| Communicable Diseases, Acute inflammation | Altered Intercellular Communication | Toxic Anterior Segment Syndrome is a sterile postoperative inflammation due to any non infectious substance that reaches the anterior segment during surgery. | 19728242 |
| Inflammation, Data types - Address, Agitation | Altered Intercellular Communication | The increased IL-1beta and decreased NKCA with the progress of agitation in AD suggest that inflammation produces agitation and aggravates AD. | 19728317 |
| Traumatic injury, Malignant Neoplasms | Altered Intercellular Communication | Indications for the CT scans included malignancy, inflammatory conditions and blunt trauma. | 19729157 |
| Hypercholesterolemia, atherosclerotic | Altered Intercellular Communication | Pitavastatin significantly reduced the elevated plasma levels of PTX3 in patients with hypercholesterolemia by its pleiotropic effect against atherosclerotic inflammation. | 19729861 |
| Inflammation, diabetic | Altered Intercellular Communication | Pitavastatin improved serum lipid profiles and reduced serum hsCRP levels in type 2 diabetic patients with relatively low inflammation. | 19729863 |
| Inflammation, Atherosclerosis | Altered Intercellular Communication | Since inflammation is an important contributor to atherosclerosis, gene variants mediating inflammation are of interest. | 19729864 |
| Intraocular inflammation | Altered Intercellular Communication | Mild to moderate intraocular inflammation was detected in 7 eyes. | 19729985 |
| Gastrointestinal inflammation | Altered Intercellular Communication | Recent studies suggest potential roles of the endocannabinoid system in gastrointestinal inflammation. | 19730730 |
| Inflammatory Bowel Diseases | Altered Intercellular Communication | Endocannabinoids signaling pathway, through CB(2) receptor, may reduce colitis-associated inflammation suggesting a potential drugable target for the treatment of inflammatory bowel diseases. | 19730730 |
| Cessation of life, Hernia, acute diverticulitis | Altered Intercellular Communication | Death was caused by intestinal herniation through a defect created by the greater omentum that had adhered to an area of acute serosal inflammation associated with underlying acute diverticulitis of the jejunum. | 19733337 |
| Inflammation | Altered Intercellular Communication | sCD14 and endotoxin, together with other markers of inflammation and protein-energy wasting. | 19733948 |
| Inflammation | Altered Intercellular Communication | sCD14 level is associated with inflammation and protein-energy wasting in hemodialysis patients. | 19733948 |
| Refractory anemias, Inflammation | Altered Intercellular Communication | We hypothesized that the inhibitory FcgammaRIIb inhibits TLR responses on monocyte-derived dendritic cells (DC) and serves as a counterregulatory mechanism to dampen inflammation, and we surmised that this mechanism might be defective in RA. | 19734236 |
| Arterial Stiffness, Rheumatoid Arthritis | Altered Intercellular Communication | Etanercept improves inflammation-associated arterial stiffness in rheumatoid arthritis. | 19734293 |
| Arterial Stiffness, Inflammation, Refractory anemias | Altered Intercellular Communication | Systemic inflammation (CRP) is an independent predictor of arterial stiffness and pulse wave reflection in patients with RA. | 19734293 |
| Inflammation, Rheumatoid Factor | Altered Intercellular Communication | Laboratory tests presented normal acute phase reactants of inflammation as well as the rheumatoid factor, CK, and negative results for antinuclear, anti-DNA, anti-SSA/Ro, and anti-CCP (ELISA) antibodies. | 19734739 |
| Inflammation, Atherosclerosis | Altered Intercellular Communication | Studies have linked smoking to inflammation, platelet activation and enhanced atherosclerosis. | 19734779 |
| Interstitial inflammation, Kidney Diseases | Altered Intercellular Communication | Within the BK nephropathy group, samples with tubular basement membrane stain had more infected tubular epithelial cells (12.1+/-7.6% vs 4.4+/-5.0%, P=0.03) and a trend toward higher interstitial inflammation scores. | 19734851 |
| Inflammation | Altered Intercellular Communication | Chronic inflammation and exogenous insulin usage increases serum syndecan-1 level. | 19735958 |
| Inflammation, Malnutrition, Chronic Kidney Diseases, Atherosclerosis | Altered Intercellular Communication | The aim of this study was to look for correlation between the markers for malnutrition and inflammation, and atherosclerosis in predialysis chronic kidney disease (CKD) patients. | 19736479 |
| Inflammation | Altered Intercellular Communication | Highly sensitive C-reactive protein (hsCRP) was assayed as a marker of chronic inflammation. | 19736479 |
| Inflammation, Malnutrition | Altered Intercellular Communication | Our results indicate that a high degree of inflammation and malnutrition exists in predialysis patients as seen by high CRP values and low serum albumin levels. | 19736479 |
| Inflammation, Hernia | Altered Intercellular Communication | Despite small differences in outcome and length of hospitalisation between Amyand types, appendix inflammation, pre-operative blood examinations and hernia localisation, only right lower quadrant peritonism as a presenting sign (p=0.004) and age greater than 90 years old (p=0.04) were significantly associated with a poor outcome. | 19736884 |
| Airway structure, ARCN1 gene | Altered Intercellular Communication | We identify some Gc-insensitive cytokines, including GM-CSF, G-CSF and IL-8, that may be involved in the progression of airway inflammation in COPD patients. | 19737233 |
| Inflammation | Altered Intercellular Communication | In vitro studies suggested that nitrite may play a cytoprotective role in inflammation. | 19737619 |
| Inflammation | Altered Intercellular Communication | Regular aerobic exercise improves FMD in sHT patients, and changes of lipids and inflammation during the exercise period may partially contribute to the improvement of endothelial function. | 19737872 |
| Adenocarcinoma of colon | Altered Intercellular Communication | Association of inflammation-related and microRNA gene expression with cancer-specific mortality of colon adenocarcinoma. | 19737943 |
| Inflammation, "Alzheimers Disease | Altered Intercellular Communication | Systemic inflammation and disease progression in Alzheimer disease. | 19738171 |
| Inflammation, Tumor necrosis | Altered Intercellular Communication | Acute and chronic systemic inflammation are characterized by the systemic production of the proinflammatory cytokine tumor necrosis factor alpha (TNF-alpha) that plays a role in immune to brain communication. | 19738171 |
| Inflammation, Nerve Degeneration | Altered Intercellular Communication | Previous preclinical research shows that acute systemic inflammation contributes to an exacerbation of neurodegeneration by activation of primed microglial cells. | 19738171 |
| Inflammation, "Alzheimers Disease | Altered Intercellular Communication | To determine whether acute episodes of systemic inflammation associated with increased TNF-alpha would be associated with long-term cognitive decline in a prospective cohort study of subjects with Alzheimer disease. | 19738171 |
| Inflammation, Tumor necrosis, Impaired cognition, "Alzheimers Disease | Altered Intercellular Communication | Both acute and chronic systemic inflammation, associated with increases in serum tumor necrosis factor alpha, is associated with an increase in cognitive decline in Alzheimer disease. | 19738171 |
| Inflammation, Neoplasms, Necrosis | Altered Intercellular Communication | Transcatheter arterial embolization (TAE) destroys a tumor by the induction of necrosis and/or apoptosis and causes inflammation with cytokine production, which may favor immune activation and presentation of tumor-specific antigens. | 19739081 |
| Inflammation | Altered Intercellular Communication | Non-diagnostic pathology results were classified into three groups: (i) atypical cells, (ii) non-specific inflammation and (iii) inadequate specimen. | 19740264 |
| Inflammation, Malignant Neoplasms | Altered Intercellular Communication | In two patients (3.8%) the lesions reported as non-specific inflammation were eventually confirmed as malignancies. | 19740264 |
| Inflammation, Metabolic Syndrome X | Altered Intercellular Communication | Here, we show that Wrn mutant mice also develop premature liver sinusoidal endothelial defenestration along with inflammation and metabolic syndrome. | 19741171 |
| Alkalosis, Respiratory | Altered Intercellular Communication | The current leading hypotheses are that respiratory alkalosis produces an as yet unidentified change in neural excitability or that inflammatory mediators potentiate excitatory synaptic transmission. | 19743470 |
| Epithelial hyperplasia, Inflammation | Altered Intercellular Communication | Nine out of the 63 patients presented with oral clinical lesions, however, most of them presented with unspecific chronic inflammation and typical epithelial hyperplasia. | 19743619 |
| Pleurisy | Altered Intercellular Communication | No patients had signs of peritoneal or pleural inflammation as the possible cause of CA-125 rise. | 19744744 |
| Pain Distress Question, Inflammation, Edema, Lipodermatosclerosis, Hyperpigmentation | Altered Intercellular Communication | The main outcome measure was venous clinical severity scores (pain, oedema, inflammation, hyperpigmentation and lipodermatosclerosis). | 19744867 |
| Pain Distress Question, Inflammation, Edema | Altered Intercellular Communication | The mean venous clinical severity scores measured before and after 180 days were as follows: Surgery group - pain: before 1.97 standard deviation (SD) 0.19, 180 days 0.72 SD 0.53; oedema: before 1.66 SD 0.48, 180 days 0.55 SD 0.63; inflammation: before 1.55 SD 0.63, 180 days 0.72 SD 0.45. | 19744867 |
| Pain Distress Question, Inflammation, Edema | Altered Intercellular Communication | Foam sclerotherapy group - pain: before 1.81 SD 0.40, 180 days 0.56 SD 0.51; oedema: before 1.70 SD 0.47, 180 days 0.48 SD 0.64; inflammation: before 1.67 SD 0.68, after 0.89 SD 0.32. | 19744867 |
| Primary malignant neoplasm | Altered Intercellular Communication | Substantial evidence supports an association between chronic infections/inflammation, and cancer. | 19745222 |
| Inflammation, Fibrosis Assessment, Nesidioblastosis, Acinar Cell | Altered Intercellular Communication | Histopathologic specimens from the pancreas were evaluated for presence and severity of fibrosis, acinar cell atrophy, inflammation, and nesidioblastosis by a surgical pathologist blinded to clinical information. | 19745778 |
| Inflammation, Fibrosis Assessment, Necrosis | Altered Intercellular Communication | Hematoxylin and eosin (H&E)-stained slides were semiquantitated for evidence of necrosis, myocytolysis, interstitial fibrosis, replacement fibrosis, and the presence of inflammation. | 19747852 |
| Weight decreased, Non-Small Cell Lung Carcinoma | Altered Intercellular Communication | The relationship between the insulin-like growth factor-1 axis, weight loss, an inflammation-based score and survival in patients with inoperable non-small cell lung cancer. | 19748165 |
| Inflammation, Non-Small Cell Lung Carcinoma | Altered Intercellular Communication | In summary, the results of this study suggest that anabolism (IGF-1 axis) does not play a significant role in the relationship between nutritional and functional decline, systemic inflammation and poor survival in patients with inoperable NSCLC. | 19748165 |
| Aneurysm, Inflammation | Altered Intercellular Communication | Abdominal computed tomography showed a 3.8 cm wide aneurysm of the distal part of the aorta with inflammation. | 19748223 |
| Vasculitis of large artery, Inflammation | Altered Intercellular Communication | Therefore, WG should be included in the work-up of large-vessel vasculitis, which can give rise to periaortic inflammation. | 19748223 |
| Inflammation, Obesity | Altered Intercellular Communication | Normal weight obesity: relationship with lipids, glycaemic status, liver enzymes and inflammation. | 19748248 |
| Inflammation, Obesity | Altered Intercellular Communication | Normal weight obesity (NWO) is defined as an excessive body fat associated with a normal body mass index (BMI) and has been associated with early inflammation, but its relationship with cardiovascular risk factors await investigation. | 19748248 |
| Inflammation, Sarcomatoid Features, Carcinoma | Altered Intercellular Communication | Microscopically these proliferations were characterized by foci of inflammation or plexiform or solid epithelial proliferations, one of which showed a focus of carcinoma in situ, adenomatoid differentiation and another osteodentin deposits. | 19748290 |
| Inflammation, Fibrosis Assessment | Altered Intercellular Communication | Only colonies with adjacent tissue reaction (inflammation, fibrosis) were analyzed. | 19748292 |
| Panuveitis, Inflammatory abnormality of the eye, Scleritis, Uveitis, Anterior uveitis | Altered Intercellular Communication | Among 384 patients (639 eyes) observed from the point of addition of methotrexate to an anti-inflammatory regimen, 32.8%, 9.9%, 21.4%, 14.6%, 15.1%, and 6.3%, respectively, had anterior uveitis, intermediate uveitis, posterior or panuveitis, scleritis, ocular mucous membrane pemphigoid, and other forms of ocular inflammation. | 19748676 |
| Juvenile Temporal Arteritis, Inflammation | Altered Intercellular Communication | Juvenile temporal arteritis (JTA) is a nongranulomatous inflammation of the temporal artery with fragmentation of the internal elastic lamina and no concurrent systemic manifestations. | 19748701 |
| Inflammation, Intimal proliferation | Altered Intercellular Communication | We present a case of a 36-year-old Jamaican woman with a painful forehead nodule that showed histologic features of JTA, including intimal hyperplasia, lymphoeosinophilic inflammation of the vessel wall, and disruption of the internal elastic lamina; distinctive signet ringlike cytomorphologic alterations of the endothelial cells were noted as well. | 19748701 |
| Interstitial inflammation | Altered Intercellular Communication | Autopsy showed diffuse interstitial inflammation of both lungs consistent with drug-induced inflammation. | 19749395 |
| Inflammation, Coronary Arteriosclerosis, Coronary heart disease | Altered Intercellular Communication | Systemic and local inflammation plays a prominent role in the pathogenesis of atherosclerotic coronary artery disease, but the relationship of whole blood gene expression changes with coronary disease remains unclear. | 19750006 |
| Inflammation, Myocardial Ischemia | Altered Intercellular Communication | The effect of gaseous traffic-related air pollution on inflammation may be stronger in genetic subpopulations with ischemic heart disease. | 19750100 |
| Immunologic Deficiency Syndromes, HIV Infections | Altered Intercellular Communication | As those with HIV infection live longer, 'non-AIDS' condition associated with immunodeficiency and chronic inflammation are more common. | 19751364 |
| Inflammation, Infection caused by Helicobacter pylori | Altered Intercellular Communication | A population-based epidemiologic study of Helicobacter pylori infection and its association with systemic inflammation. | 19751435 |
| Inflammation | Altered Intercellular Communication | These may be mediated by an increase in systemic inflammation. | 19751435 |
| Communicable Diseases, Inflammation | Altered Intercellular Communication | Our data suggest that infection with H. pylori is associated with increased systemic inflammation. | 19751435 |
| Inflammation, "Alzheimers Disease", Impaired cognition, millicurie | Altered Intercellular Communication | Inflammation is proposed to play a role in the development of Alzheimer's disease, and may also be involved in the pathogenesis of mild cognitive impairment (MCI). | 19751919 |
| Inflammation, millicurie | Altered Intercellular Communication | These findings suggest the involvement of inflammation in the pathogenesis of MCI. | 19751919 |
| Atrial Fibrillation, Inflammation, Atrial Fibrillation by ECG Finding, Ischemia | Altered Intercellular Communication | The risk of atrial fibrillation (AF) after coronary bypass surgery has been related to redox state, inflammation, and ischemia. | 19752364 |
| Oligospermia, Primary hypogonadism | Altered Intercellular Communication | Hormonal examination demonstrated hypergonadotropic hypogonadism, semen analysis showed severe oligoasthenoteratozoospermia. | 19752597 |
| Ischemia, Inflammation | Altered Intercellular Communication | Enterocyte shedding and epithelial lining repair following ischemia of the human small intestine attenuate inflammation. | 19753114 |
| Pleural Effusion, CTCAE, Granulomatous inflammation, Pneumonia, Interstitial, Pneumonia | Altered Intercellular Communication | Pleural effusion associated with pegylated interferon alpha and ribavirin treatment for chronic hepatitis C. Lung toxicity related to interferon (IFN) alpha typically takes a form of interstitial pneumonitis, granulomatous inflammation, or organizing pneumonia. | 19753589 |
| Cystic Adenomatoid Malformation of Lung, Congenital, Inflammation | Altered Intercellular Communication | Inflammation can be present in infantile congenital cystic adenomatoid malformation of the lung. | 19753732 |
| Cystic Adenomatoid Malformation of Lung, Congenital, Inflammation, Infancy | Altered Intercellular Communication | The absence of inflammation has generally been considered obligatory for the diagnosis of CCAM of the lung in the infantile period. | 19753732 |
| Inflammation, Structure of parenchyma of lung | Altered Intercellular Communication | Furthermore, it has been argued that chronic inflammation itself may influence the development of cystic lesions within lung parenchyma. | 19753732 |
| Suppurative inflammation, Deformity | Altered Intercellular Communication | We report a case of an 11-month-old infant with CCAM malformation of the lung type III associated with a super-impossed purulent inflammation and abscess formation. | 19753732 |
| Pain Distress Question | Altered Intercellular Communication | The second generation was heralded by research that demonstrated that newborns did demonstrate similar or even exaggerated physiological and hormonal responses to pain compared with those observed in older children and adults and that exposure to prolonged or severe pain may increase neonatal morbidity. | 19754486 |
| Inflammation, Neoplasms | Altered Intercellular Communication | Further diagnostic work-up included a fluorodeoxyglucose positron emission tomography (FDG-PET) of the whole body to search for occult inflammation or neoplasia. | 19755199 |
| Inflammation, therapeutic hemodilution | Altered Intercellular Communication | Clinical evaluation of minimized extracorporeal circulation in high-risk coronary revascularization: impact on air handling, inflammation, hemodilution and myocardial function. | 19755462 |
| Inflammation, Colorectal Carcinoma | Altered Intercellular Communication | Chronic inflammation plays an important role in the development and progression of colorectal cancer. | 19755647 |
| Inflammation, pertussis vaccine | Altered Intercellular Communication | Booster doses of diphtheria-tetanus-acellular pertussis (DTaP) vaccines restore waning serum antibody values but frequently cause local inflammation. | 19755930 |
| Granuloma, Inflammation, Muscle hypertrophy, Ileitis, Ulcer, Lobular Endocervical Glandular Hyperplasia, Hypertrophy, Ileal ulcer | Altered Intercellular Communication | The following atypical features were identified (n; %): broad-based ulcer (99; 65%), appendiceal involvement (78; 51%), V-shaped ulcer (48; 31%), crypt-associated granuloma (42; 27%), isolated giant cells (39; 25%), discontinuous active inflammation (36; 24%), slit-like fissure (32; 21%), discontinuous chronic inflammation (16; 10%), ileal villous architectural distortion (12; 8%), neural hypertrophy (10; 7%), backwash ileitis (10; 7%), transmural inflammation (8; 5%), discontinuous ileitis (8; 5%), muscle hypertrophy (5; 3%), ileal ulcer (4; 3%), and ileal pyloric metaplasia (1; 1%). | 19755970 |
| Systemic Inflammatory Response Syndrome | Altered Intercellular Communication | Six patients developed inflammation-related complications (Systemic Inflammatory Response Syndrome--SIRS) and they all showed a deeper postoperative decrease of FT3 value than non complicated subjects, even if the difference was not statistically significant (1st postop day 3.60 +/- 1.05 vs 2.47 +/- 0.61 p = 0.06). | 19756315 |
| Inflammation, Atherosclerosis | Altered Intercellular Communication | Preoperative FT3 value in patients with atherosclerosis is inversely correlated with markers of inflammation activity, mainly with fibrinogen. | 19756315 |
| Muscle of orbit, Myositis | Altered Intercellular Communication | On magnetic resonance (MR) imaging, muscle inflammation was measured with a region of interest set within the brightest extra-ocular muscle both on coronal turbo inversion recovery magnitude (TIRM) and on fat suppressed gadolinium-enhanced T1-weighted sequences. | 19756565 |
| Pain Distress Question, Inflammation | Altered Intercellular Communication | The subjects were 16 patients (20 shoulders) in whom pain was possibly derived from inflammation of the SAB. | 19756670 |
| Inflammation, Lupus Erythematosus, Systemic | Altered Intercellular Communication | Abnormal activation of intracellular signaling molecules in lymphocytes by inflammatory cytokines can instigate the inflammation in SLE. | 19756990 |
| Hyperactive behavior, Inflammation Mediators, Lupus Erythematosus, Systemic | Altered Intercellular Communication | The inflammation-mediated activation of JNK and p38 MAPK signaling pathways in T and B lymphocytes can be the underlying intracellular mechanisms causing lymphocyte hyperactivity in SLE. | 19756990 |
| Crohn Disease, Inflammation | Altered Intercellular Communication | Infliximab in clinical routine: experience with Crohn's disease and biomarkers of inflammation over 5 years. | 19757522 |
| Inflammation, Lung Diseases, Obstructive, Intestinal Diseases, Ischemia | Altered Intercellular Communication | This finding may present in diverse conditions, such as obstructive pulmonary disease and intestinal disease, including obstruction, inflammation, or ischemia. | 19758151 |
| Coughing, ARCN1 gene, Hypersensitivity, Airway structure | Altered Intercellular Communication | Hypersensitivity of the cough reflex to inhaled capsaicin might reflect airway inflammation in stable COPD patients, which predisposes to frequent exacerbations. | 19761536 |
| Inflammation, Community acquired pneumonia | Altered Intercellular Communication | Biological markers as an expression of systemic inflammation have been recognised as useful for evaluating the host response in community-acquired pneumonia (CAP). | 19762338 |
| Inflammation, Liver damage | Altered Intercellular Communication | In addition, MRP14-deficient mice demonstrated decreased systemic inflammation, as reflected by lower cytokine plasma concentrations, and less severe liver damage. | 19762566 |
| Inflammation | Altered Intercellular Communication | Abdominal fat deposition is associated with increased inflammation, protein-energy wasting and worse outcome in patients undergoing haemodialysis. | 19762603 |
| HD Term Type, Inflammation | Altered Intercellular Communication | We tested the hypothesis that abdominal fat deposition in HD patients is a risk factor associated with both increased inflammation and protein-energy wasting (PEW), as well as elevated mortality risk. | 19762603 |
| Inflammation | Altered Intercellular Communication | Abdominal fat deposition in haemodialysis patients is linked to both inflammation and PEW, resulting in an increased mortality risk. | 19762603 |
| Necrosis | Altered Intercellular Communication | The anti-tumor necrosis factor (TNF)alpha medications demonstrate efficacy in the induction of remission and its maintenance in numerous chronic inflammatory conditions. | 19764100 |
| Pain Distress Question, Inflammation | Altered Intercellular Communication | Pain and signs of inflammation in the eye recurred after 2 weeks. | 19765479 |
| Inflammation, Diabetes Mellitus, Non-Insulin-Dependent, Cardiovascular Diseases | Altered Intercellular Communication | Insulin resistance and inflammation may have an additional role in the link between cystatin C and cardiovascular disease in type 2 diabetes mellitus patients. | 19765773 |
| Inflammation | Altered Intercellular Communication | It may be worthwhile to focus on increasing the resilience of the airways to environmental insults in addition to improving strategies that modify adaptive immunity or suppress inflammation. | 19766079 |
| vascular inflammations, Endothelial dysfunction, Atherosclerosis | Altered Intercellular Communication | Important biochemical markers for the low-grade vascular inflammation and endothelial dysfunction that characterize the earliest events in the pathogenesis of atherosclerosis are CRP and the adhesion molecules ICAM-1 and VCAM-1. | 19766219 |
| Inflammation, Arrhythmogenic Right Ventricular Dysplasia, Metabolic Syndrome X, Atherosclerosis | Altered Intercellular Communication | Increased left ventricular arrhythmogenicity in metabolic syndrome and relationship with myocardial performance, risk factors for atherosclerosis, and low-grade inflammation. | 19766273 |
| Inflammation, Myocardial dysfunction, Atherosclerosis, ETV3 wt Allele, Arrhythmogenic Right Ventricular Dysplasia | Altered Intercellular Communication | In conclusion, ventricular arrhythmogenicity is present in MetS and is associated with myocardial dysfunction, risk factors for atherosclerosis, and low-grade inflammation. | 19766273 |
| Heart Diseases, Inflammation | Altered Intercellular Communication | This association does not appear to be mediated by co-morbid conditions, cardiac disease severity, insulin resistance, inflammation, neurohormones, or adipokines. | 19766751 |
| Heart Diseases, Inflammation | Altered Intercellular Communication | This association does not appear to be mediated by co-morbid conditions, cardiac disease severity, insulin resistance, inflammation, neurohormones, or adipokines. | 19766751 |
| Alzheimers Disease", Data types - Address | Altered Intercellular Communication | The associations of inflammation/immune responses with clinical presentations of Alzheimer's disease (AD) remain unclear. | 19767111 |
| Gingivitis, Inflammation, Periodontitis, Periodontal Diseases, Dental Plaque | Altered Intercellular Communication | Periodontal diseases, such as gingivitis and periodontitis, are characterized by bacterial plaque accumulation around the gingival crevice and the subsequent inflammation and destruction of host tissues. | 19767584 |
| Inflammation, Phase II/III Trial, Colorectal Carcinoma | Altered Intercellular Communication | The present study assesses the prognostic value of local and systemic inflammation in colon and rectal cancers and defines 3-year survival according to inflammation-based criteria for stage II/III disease. | 19768511 |
| Inflammation, Hyperplasia, Psoriasiform lesion, Follicular cyst | Altered Intercellular Communication | A skin biopsy was performed for each patient demonstrating cystic follicular dilatation with keratin plugging, dermal scarring, psoriasiform epidermal hyperplasia, and chronic inflammation of some of the follicles. | 19769836 |
| Macular Edema, Cystoid, Intraocular inflammation | Altered Intercellular Communication | Funduscopic examination revealed cystoid macular edema with no intraocular inflammation. | 19769861 |
| Endophthalmitis, CTCAE | Altered Intercellular Communication | The next day, endophthalmitis was diagnosed secondary to exuberant purulent inflammation. | 19770723 |
| Inflammation, Hypertension, CTCAE, Endothelial dysfunction | Altered Intercellular Communication | Biomarkers of inflammation and endothelial dysfunction and risk of hypertension among Inner Mongolians in China. | 19770776 |
| Inflammation, Hypertension, CTCAE, Endothelial dysfunction | Altered Intercellular Communication | These data suggest that inflammation and endothelial dysfunction may play a role in the cause of hypertension. | 19770776 |
| HD Term Type, "Huntingtons Disease Pathway | Altered Intercellular Communication | We investigated, retrospectively, the prevalence of gastroesophageal inflammation in patients with Huntington's disease (HD) during 10 years in our center. | 19771391 |
| Multinodular, Inflammation, Insect Bites, Dental Plaque | Altered Intercellular Communication | The patient had no remarkable medical history, no history of either acute inflammation or insect bite, and presented with a 5 cm solitary asymptomatic erythematous firm, multinodular and infiltrated plaque on the back for 12 months. | 19771768 |
| Inflammation, Ischemia | Altered Intercellular Communication | We hypothesize that stress-induced response by inflammation and/or ischemia may interfere in the physiological barrier that prevents any significant amount of PSA to gain the general circulation. | 19773041 |
| Inflammation | Altered Intercellular Communication | We tested whether organisational injustice contributes to chronic inflammation in a population of middle-aged men and women. | 19773285 |
| Inflammation, Carcinoma of lung, Pain Distress Question | Altered Intercellular Communication | Role of inflammation gene polymorphisms on pain severity in lung cancer patients. | 19773451 |
| Inflammation, Carcinoma of lung, Pain Distress Question | Altered Intercellular Communication | Therefore, we evaluated 59 single nucleotide polymorphisms in 37 inflammation genes in newly diagnosed non-Hispanic Caucasian lung cancer patients (n = 667) and assessed their association with pain severity. | 19773451 |
| Inflammation, Pain Distress Question | Altered Intercellular Communication | This study suggests the importance of inflammation gene polymorphisms in modulating pain severity. | 19773451 |
| Inflammation, Hodgkin Disease | Altered Intercellular Communication | Inflammation and tissue repair markers distinguish the nodular sclerosis and mixed cellularity subtypes of classical Hodgkin's lymphoma. | 19773754 |
| malignant disease, Hodgkin Disease | Altered Intercellular Communication | Classical Hodgkin's lymphoma (cHL), although a malignant disease, has many features in common with an inflammatory condition. | 19773754 |
| Inflammatory Bowel Diseases, Inflammatory disease of mucous membrane | Altered Intercellular Communication | There is increasing evidence that psychological stress can increase mucosal inflammation and worsen the course of inflammatory bowel disease (IBD). | 19774642 |
| Single organ dysfunction, Inflammation, Critical Illness | Altered Intercellular Communication | Inflammation, vitamin deficiencies and organ failure in critically ill patients. | 19775037 |
| Inflammation | Altered Intercellular Communication | It is unknown whether biochemical vitamin deficiencies in critical illness are associated with severity of illness, organ dysfunction, inflammation or mortality. | 19775037 |
| Loss, Inflammation, AICARDI-GOUTIERES SYNDROME | Altered Intercellular Communication | The gastrointestinal tract is an area of high cell loss, revealing early signs of systemic inflammation and we postulate that a systemic proinflammatory milieu occurs in Aicardi-Goutieres syndrome. | 19775308 |
| Gastrointestinal inflammation | Altered Intercellular Communication | Gastrointestinal inflammation should also be considered in these patients and treated appropriately. | 19775308 |
| Burning sensation, Inflammation, Xerostomia | Altered Intercellular Communication | The high prevalence of oral parafunctional habits and dry mouth symptoms in patients with BMS suggests that inflammation at the subclinical level due to repetitive microtrauma may cause burning mouth sensations. | 19775760 |
| Intermittent Claudication, Inflammation | Altered Intercellular Communication | Exercise in patients with intermittent claudication elicits signs of inflammation and angiogenesis. | 19775917 |
| Inflammation, Coronary Arteriosclerosis | Altered Intercellular Communication | There are contributions to understanding individual differences in normal cognitive ageing from genetics, general health and medical disorders such as atherosclerotic disease, biological processes such as inflammation, neurobiological changes, diet and lifestyle. | 19776035 |
| Inflammation, Muscular Atrophy, Blood Circulation | Altered Intercellular Communication | Patients with previous circulatory congestion had significantly more inflammation, more muscle wasting, and higher REE but lower activity energy expenditure and energy and protein intakes in keeping with an anorexia-cachexia syndrome. | 19776138 |
| Inflammation | Altered Intercellular Communication | The HFr group had a significantly higher grade of lobular inflammation than the other 4 groups. | 19776184 |
| Inflammation, Fatty Liver Disease | Altered Intercellular Communication | The distribution of lobular inflammation was predominant over portal inflammation, which is consistent with human NASH. | 19776184 |
| Inflammation | Altered Intercellular Communication | EGCG may be of value in the treatment of synovial inflammation. | 19777241 |
| Gastrointestinal dysmotility | Altered Intercellular Communication | These data suggest that SSc GI dysmotility may be caused by autoantibodies that inhibit the muscarinic neurotransmission. | 19779020 |
| Vascular Diseases, Inflammation, Telangiectasis, Raynaud Phenomenon, CREST Syndrome, Fibrosis Assessment, Scleroderma , Sclerodactyly, Calcinosis, Esophageal hypomotility | Altered Intercellular Communication | CREST syndrome is a variant of scleroderma characterized by calcinosis, Raynaud's phenomenon, esophageal hypomotility, sclerodactyly, and telangiectasia, and is a collagen vascular disease characterized by inflammation and fibrosis of multiple organs/tissues. | 19779284 |
| Inflammation, Necrosis | Altered Intercellular Communication | The histological examination revealed lobulated fibrofatty tissue showing congestion, acute inflammation and fat necrosis. | 19779995 |
| Inflammation, Heart failure | Altered Intercellular Communication | Red cell distribution width in heart failure: prediction of clinical events and relationship with markers of ineffective erythropoiesis, inflammation, renal function, and nutritional state. | 19781428 |
| Renal Insufficiency, Inflammation | Altered Intercellular Communication | The described correlations between RDW and inflammation, ineffective erythropoiesis, undernutrition, and impaired renal function may facilitate the understanding why this marker is associated with adverse outcomes in HF. | 19781428 |
| Inflammation, Terminal Osseous Dysplasia and Pigmentary Defects | Altered Intercellular Communication | Inflammation and sympathetic overdrive may also associate with TOD. | 19781703 |
| Inflammation, Diabetes Mellitus, Non-Insulin-Dependent | Altered Intercellular Communication | Association of LDL cholesterol and inflammation with cardiovascular events and mortality in hemodialysis patients with type 2 diabetes mellitus. | 19781835 |
| Pneumonitis | Altered Intercellular Communication | Imaging at 6 months demonstrated no anastomotic concerns and resolution of residual pulmonary inflammation. | 19782515 |
| Inflammation | Altered Intercellular Communication | Log leptin, adiponectin and L/A ratio were significantly associated with variables of systemic inflammation, after proper adjustments, both on admission and in stable condition. | 19782551 |
| Inflammation, Immunoglobulin G4 deficiency | Altered Intercellular Communication | There was a significant association between severity of gingival inflammation and reduced number of B- and/or CD3+/CD4+ T cells combined with IgA+IgG4 deficiency. | 19782616 |
| Inflammation, Atherosclerosis | Altered Intercellular Communication | Accumulating evidence suggests that inflammation plays an essential role in the pathogenesis of atherosclerosis. | 19784814 |
| Inflammation, Anterior uveitis | Altered Intercellular Communication | In patients with CMV anterior uveitis, intravitreal ganciclovir injection as a loading dose with or without the following oral valganciclovir can control the inflammation and IOP well. | 19784845 |
| Autoimmune Diseases, Lupus Erythematosus | Altered Intercellular Communication | Background Lupus erythematosus (LE) is a chronic, autoimmune disease resulting from an interaction of genetic, environmental and hormonal factors and characterized by a spectrum of clinical forms with variable evolution from a localized cutaneous form to a life-threatening systemic form. | 19785596 |
| Inflammation, Dermatitis, Atopic, Skin Diseases, Eczematous, Data types - Address, Dryness (characteristic), Pruritus | Altered Intercellular Communication | Atopic dermatitis (AD) is a chronic relapsing eczematous skin disease characterized by pruritus and inflammation and accompanied by cutaneous physiological dysfunction (dry and barrier-disrupted skin). | 19785716 |
| Granulomatous inflammation | Altered Intercellular Communication | Brain biopsy revealed granulomatous inflammation and remnants of worm eggs. | 19785826 |
| Inflammation, Chronic sinusitis | Altered Intercellular Communication | Biofilms correlate with TH1 inflammation in the sinonasal tissue of patients with chronic rhinosinusitis. | 19786211 |
| Inflammation, Sarcoidosis | Altered Intercellular Communication | By using antigenic peptides presented in vivo in the lungs of sarcoidosis patients, we have identified blood and lung T cell autoimmune responses that may help sustain the inflammation in this disease. | 19786367 |
| Inflammation, Diabetes Mellitus, Non-Insulin-Dependent | Altered Intercellular Communication | Effect of pioglitazone on systemic inflammation is independent of metabolic control and cardiac autonomic function in patients with type 2 diabetes. | 19787290 |
| Blepharitis, Asthma, Conjunctivitis, Diabetes Mellitus | Altered Intercellular Communication | The patients were divided into four groups: a control group (without local or systemic risk factors), those with local risk factors (chronic use of topical medications, contact lens wear, blepharitis, chronic eyelid or conjunctival inflammation), those with systemic risk factors (immunosuppression, diabetes, autoimmune conditions, and asthma), and those with both. | 19787587 |
| palladium | Altered Intercellular Communication | While some of these cells likely undergo degeneration, the strong up-regulation of Herp in glia could help to explain the inflammation-like changes observed in PD ("neuroinflammation") as it has been shown that the unfolded protein response serves as an important regulator of inflammatory genes in other organs. | 19788048 |
| Refractory anemias, Rheumatoid Arthritis, Inflammation | Altered Intercellular Communication | Rheumatoid arthritis (RA) characterized by local and systemic effects of inflammation has a wide range of biochemical markers implicated directly or indirectly to its pathogenesis. | 19788068 |
| Optic perineuritis | Altered Intercellular Communication | Optic perineuritis (OPN) is an inflammatory condition involving the optic nerve sheath because of a variety of causes. | 19788669 |
| Malaria, Falciparum, Peripheral gangrene, Plasmodium falciparum, SLC25A10 gene | Altered Intercellular Communication | [DIC and peripheral gangrene in a severe Plasmodium falciparum malaria: the coagulation-inflammation cycle with Plasmodium falciparum as a model]. | 19789130 |
| Inflammation, Malaria, SLC25A10 gene | Altered Intercellular Communication | Pathophysiological mechanisms leading to DIC in malaria can be used as a model to explain the relation between coagulation and inflammation. | 19789130 |
| Inflammation | Altered Intercellular Communication | Therapeutic targeting of coagulation, by acting on inflammation, could be useful to limit the coagulation-inflammation cycle. | 19789130 |
| Inflammation, Asthma | Altered Intercellular Communication | To analyze and compare computed tomographic (CT) bronchial measurements in patients with asthma and healthy subjects and to correlate bronchial morphometric parameters with functional data and immunohistologic markers of airway remodeling and inflammation. | 19789219 |
| Colorectal Carcinoma | Altered Intercellular Communication | As one of the largest data sets analyzed to establish that younger women with MCRC survive longer than younger men, hormonal status not only seems to play an important role in the development and pathogenesis of colorectal cancer but also may be of prognostic significance. | 19789331 |
| ARCN1 gene, Respiratory Insufficiency, Inflammation, exacerbation acute | Altered Intercellular Communication | Nutritional status in relation to respiratory impairment and systemic inflammation in patients with acute exacerbations of COPD. | 19789512 |
| ARCN1 gene, Respiratory Insufficiency, Inflammation | Altered Intercellular Communication | Knowledge of the effects of undernourishment on the severity of respiratory impairment, systemic inflammation and oxidative stress during acute exacerbations of COPD (AECOPD) is limited. | 19789512 |
| Inflammation | Altered Intercellular Communication | In patients with AECOPD, we assessed the relationships between BMI, lung function, and markers of systemic inflammation and oxidative stress. | 19789512 |
| Inflammation | Altered Intercellular Communication | During the long-term follow up of 62 patients with the Frey procedure, eight patients had relapse of inflammation and required reoperation. | 19789835 |
| Inflammation, Waldenstrom Macroglobulinemia | Altered Intercellular Communication | At the time of aortic surgery, a transmural lymphoplasmacytic infiltrate was detected in the patient's aorta, with a principal focus of inflammation within the media. | 19790067 |
| Inflammation, Disease | Altered Intercellular Communication | Patients with proinflammatory HDL had higher measures of systemic inflammation, and a significant correlation was observed between RA disease activity (using the Disease Activity Score in 28 joints) and the HDL inflammatory index (r = 0.54, P < 0.0001). | 19790070 |
| Refractory anemias, Inflammation, Cardiovascular morbidity | Altered Intercellular Communication | The antiinflammatory function of HDL was inversely correlated with systemic inflammation in RA patients and may warrant further investigation as a mechanism by which active RA increases cardiovascular morbidity and mortality. | 19790070 |
| Inflammation | Altered Intercellular Communication | A preponderance of 16alpha-hydroxylated estrogens is an unfavorable sign in synovial inflammation. | 19790073 |
| Inflammatory, Inflammation | Altered Intercellular Communication | In inflammatory lesions, sympathetic nerve fibers disappear soon after the start of inflammation. | 19790074 |
| Inflammation, Autoimmune Chronic Hepatitis | Altered Intercellular Communication | In the multivariate Cox analysis, only the presence of moderate to severe inflammation (HR, 6.9; 95% CI, 1.76-26.96; P = 0.006) and high IgG levels before liver transplantation (HR, 7.5; 95% CI, 1.45-38.45; P = 0.02) were independently associated with the risk of autoimmune hepatitis recurrence. | 19790153 |
| Intraocular inflammation, NCI CTEP SDC Retinoblastoma Sub-Category Terminology | Altered Intercellular Communication | Invasive surgical procedures should be avoided in children presenting with atypical, chronic, unilateral intraocular inflammation of unknown cause until retinoblastoma is excluded. | 19791731 |
| ARCN1 gene, Inflammation, Electrocardiogram: myocardial infarction (finding) | Altered Intercellular Communication | It is also hypothesized that systemic inflammation in COPD increases the risk for cardiac events such as myocardial infarction. | 19791824 |
| Inflammation, Diabetes Mellitus | Altered Intercellular Communication | Diabetes is a proinflammatory state with increased levels of circulating cytokines suggesting a causal role for inflammation in its etiology. | 19792847 |
| Inflammation, Asthma | Altered Intercellular Communication | Eosinophilic inflammation has a central role in the pathogenesis of asthma. | 19793065 |
| Inflammation, Angioendotheliomatosis, Necrosis | Altered Intercellular Communication | Muscle biopsy showed myopathic changes, intravascular large B-cell lymphoma but no inflammation or fibre necrosis; the patient's serum cross-reacted with an unidentified nuclear antigen of approximately 45 kDa present in muscle and lymphoma cells. | 19793654 |
| Inflammation, Endotoxemia | Altered Intercellular Communication | Experimental endotoxemia induces adipose inflammation and insulin resistance in humans. | 19794059 |
| Inflammation, Metabolic Syndrome X, Diabetes Mellitus, Non-Insulin-Dependent, physiopathological | Altered Intercellular Communication | An emerging model of metabolic syndrome and type 2 diabetes is of adipose dysfunction with leukocyte recruitment into adipose leading to chronic inflammation and insulin resistance (IR). | 19794059 |
| Inflammation | Altered Intercellular Communication | We demonstrate, for the first time in humans, that acute inflammation induces systemic IR following modulation of specific adipose inflammatory and insulin signaling pathways. | 19794059 |
| Inflammation, Traumatic injury | Altered Intercellular Communication | When disturbed following PEC injury, the increase in permeability of this layer to filtered protein is a mechanism underlying periglomerular inflammation characteristic of anti-GBM disease. | 19794110 |
| RANGAP1 wt Allele, Inflammation | Altered Intercellular Communication | In the SD patients, small clusters of inflammation were found in the reticular formation surrounding solitary tract, spinal trigeminal, and ambigual nuclei, inferior olive, and pyramids. | 19795469 |
| Inflammation, Leukocytosis, Chlamydia, Vaginal Diseases, Actinomyces, Candida (fungus) | Altered Intercellular Communication | The Dutch cytological coding system, KOPAC, enables to code for eight inflammatory events, that is koilocytosis (related to human papillomavirus (HPV)), Trichomonas, dysbacteriosis [related to bacterial vaginosis (BV)], Candida, Gardnerella, Actinomyces, Chlamydia, and non-specific inflammation (leucocytosis). | 19795485 |
| Inflammation, Necrosis | Altered Intercellular Communication | Biopsy findings showed an ill defined granulomatous process with chronic inflammation and necrosis. | 19796470 |
| Orbital Pseudotumor | Altered Intercellular Communication | These data suggest a possible role for PDGF-BB in regulating orbital inflammation in GO and identify the PDGF signaling cascade as a therapeutic target in GO. | 19797221 |
| Refractory anemias, Inflammation, Rheumatoid Factor, Pneumonitis | Altered Intercellular Communication | Aseptic pulmonary nodular inflammation corresponding to rheumatoid nodules or noncaseating granulomatous inflammation can occur during anti-TNF-alpha therapy for RA, mainly etanercept. | 19797509 |
| Pneumonitis | Altered Intercellular Communication | These cases of pulmonary nodular inflammation generally have a benign course and do not systematically require withdrawal of treatment. | 19797509 |
| Inflammation, Coronary heart disease, Atherosclerosis | Altered Intercellular Communication | Hemostasis, inflammation, and fatal and nonfatal coronary heart disease: long-term follow-up of the atherosclerosis risk in communities (ARIC) cohort. | 19797708 |
| Inflammation, Cardiac Death, Electrocardiogram: myocardial infarction (finding) | Altered Intercellular Communication | This study examines the hypothesis that chronic inflammation is associated with a higher risk of cardiac death compared to the risk of nonfatal myocardial infarction. | 19797708 |
| Asthma, Bronchitis | Altered Intercellular Communication | To compare bronchial inflammation and remodeling in never-smokers, ex-smokers, and current smokers with asthma. | 19797761 |
| Cessation of life, Inflammation | Altered Intercellular Communication | The inclusion of the C-reactive protein (CRP) inflammation marker into the model highly improved the power of death prediction. | 19797975 |
| Communicable Diseases | Altered Intercellular Communication | We speculate that the pathogenesis involves increased platelet production due to megakaryopoietic stimulators induced by an infectious or inflammatory condition. | 19798040 |
| Inflammation, Obesity | Altered Intercellular Communication | Relationships among obesity, inflammation, and insulin resistance in African Americans and West Africans. | 19798069 |
| Inflammation, Obesity | Altered Intercellular Communication | Several research studies in different populations indicate that inflammation may be the link between obesity and insulin resistance (IR). | 19798069 |
| Inflammation | Altered Intercellular Communication | In both populations, BMI was associated with markers of inflammation and with HOMA(IR), and these associations remained significant after adjusting for sex and age. | 19798069 |
| Inflammation | Altered Intercellular Communication | Interestingly, none of the associations between markers of inflammation and IR remained significant after adjusting for BMI. | 19798069 |
| Left Ventricular Hypertrophy, Inflammation, Cancer-related fatigue, Arteriovenous fistula, Anemia, Hypertension, CTCAE, Chronic Kidney Diseases | Altered Intercellular Communication | After RT LVH risk factors were age, duration of chronic renal failure (CRF) and pretransplantation dialysis, reduced mass of the operating nephrons, arterial hypertension, anemia, functioning of arterio-venous fistula (AVF) and chronic inflammation syndrome. | 19799199 |
| Inflammation | Altered Intercellular Communication | Adipose tissue contributes in energy, lipid homeostasis and inflammation, through the adipokines it releases. | 19800327 |
| Asthma, MS4A2 wt Allele, Helminthiasis | Altered Intercellular Communication | Parasitic helminth infections can protect against allergic airway inflammation in experimental models and have been associated with a reduced risk of atopy and a reduced course of asthma in some observational studies. | 19800680 |
| Pneumonitis, Ulcerative Colitis | Altered Intercellular Communication | Moreover, severe lung inflammation was only observed in mice intranasally infected with the isolate from the UC form with the increase of bacterial load. | 19800962 |
| Inflammation, Fibrosis Assessment, Depressed mood, Depression, CTCAE | Altered Intercellular Communication | Inflammation markers were also elevated in depressed participants (CRP, p=0.014; WBC, p=0.075; fibrinogen, p=0.074), but these inflammation markers did not account for the relationship between depression and fibrosis markers. | 19800964 |
| Pancreatitis, AURKAIP1 gene, Pancreatic calcification, Abdominal Pain, Atrophic | Altered Intercellular Communication | In a separate cohort of patients with AIP from our database, we identified patients who presented with features of AP (>/=2 of abdominal pain, increased pancreatic enzymes, pancreatic inflammation determined by imaging analyses) or CP (>/=1 of pancreatic calcification, irregular main pancreatic duct dilation, or marked atrophy) and determined their clinical profile. | 19800984 |
| vascular inflammations, Hypertension, CTCAE, Cardiovascular Diseases | Altered Intercellular Communication | We have earlier shown that olmesartan reduces mediators of vascular inflammation in patients with hypertension and cardiovascular disease. | 19801149 |
| Inflammation, Hypertensive (finding) | Altered Intercellular Communication | Elevated osteopontin levels in hypertensive patients correlate with adhesion molecules and inflammation markers. | 19801149 |
| Inflammation, Hematoma, Edema | Altered Intercellular Communication | The relationships of residue hematoma volume to brain edema, inflammation factors and the long-term prognosis of HBGH patients were studied. | 19801153 |
| Inflammation, Back Pain | Altered Intercellular Communication | The area of inflammation appeared two days after physiotherapy sessions prescribed for lower back pain. | 19801259 |
| Inflammation, Kidney Failure | Altered Intercellular Communication | Laboratory examinations revealed inflammation associated with moderate renal failure. | 19801259 |
| Cranial nerve palsies, Disorder of the optic nerve, Inflammation, Uveitis | Altered Intercellular Communication | Although most common ophthalmologic findings include optic neuropathy and uveitis, cranial nerve palsies may also present secondary to intracranial inflammation. | 19801340 |
| Inflammation, Asthma | Altered Intercellular Communication | IL-33, a new member of the IL-1 cytokine family, promotes Th2 inflammation, but evidence on the implications of this cytokine in asthma is lacking. | 19801525 |
| Airway structure | Altered Intercellular Communication | Induced sputum cytology and protein biomarkers can be used to assess airways inflammation. | 19801580 |
| Airway structure | Altered Intercellular Communication | We hypothesized that other sputum metals may be affected by airways inflammation and investigated their potential value as biomarkers. | 19801580 |
| Airway structure, Bronchiectasis | Altered Intercellular Communication | These results suggest a relationship of high concentrations of total zinc and iron with airways inflammation in CF and non-CF bronchiectasis, with longitudinal changes being observed in CF. | 19801580 |
| Airway structure, Obesity | Altered Intercellular Communication | To investigate the association between obesity and airway inflammation and spirometric parameters in local children. | 19801691 |
| Airway structure | Altered Intercellular Communication | Increased airway inflammation as revealed by exhaled nitric oxide concentration was found in obese non-asthmatic children. | 19801691 |
| Disease, Parinaud Syndrome, Inflammatory abnormality of the eye, Juxtapapillary focal retinitis AND retinochoroiditis | Altered Intercellular Communication | It can present with a wide spectrum of ocular diseases including neuroretinitis, Parinaud's oculoglandular syndrome, and other forms of intra-ocular inflammation. | 19801700 |
| Compartment syndromes, Inflammation | Altered Intercellular Communication | This inflammation can, in rare cases, lead to the development of a compartment syndrome. | 19801954 |
| Inflammation | Altered Intercellular Communication | Ninety two percent of cases had chronic inflammation in the gallbladder wall. | 19802413 |
| Inflammation, Cachexia | Altered Intercellular Communication | Chronic inflammation is one of the main features of cancer cachexia. | 19802504 |
| Limbic Encephalitis, Temporal Lobe | Altered Intercellular Communication | MRI brain revealed bilateral temporal lobe inflammation consistent with limbic encephalitis. | 19804892 |
| Inflammation, Calcinosis | Altered Intercellular Communication | The location of the plaques, type of plaques, presence of inflammation and calcification were assessed. | 19805952 |
| Steatohepatitis, Inflammation | Altered Intercellular Communication | Inconsistent assessment of histological features of steatohepatitis (lobular inflammation, portal inflammation, hepatocyte ballooning, and Mallory hyaline) was documented. | 19806055 |
| Thrombosis of cerebral veins, Vertical Talus, Traumatic injury | Altered Intercellular Communication | Cerebral venous thrombosis was relatively more common in women and hormonal factors may predispose to CVT compared to DVT/PE, while trauma, immobilisation and surgery may be less important in the pathophysiology of CVT. | 19806246 |
| vinyltriethoxysilane, Unknown (origin) (qualifier value), Inflammation, Thromboembolism | Altered Intercellular Communication | The aim of our study was to evaluate whether elevated clotting factors, which have been linked to chronic sub-clinical inflammation and arterial thromboembolic disease, have a higher prevalence in idiopathic VTE compared to secondary VTE. | 19806251 |
| vinyltriethoxysilane, Unknown (origin) (qualifier value), Inflammation, Arterial thromboembolism | Altered Intercellular Communication | Our data show that markers of inflammation, such as hs-CRP, fibrinogen, and factor VIII, are at higher levels in patients with idiopathic compared to secondary VTE, supporting the hypothesis that idiopathic VTE and arterial thromboembolism share common risk factors. | 19806251 |
| Inflammation, Dental Plaque | Altered Intercellular Communication | Such platelet-mediated inflammation could be involved in atherogenesis and plaque destabilisation. | 19806256 |
| Adenocarcinoma, Inflammation, Neoplasms, Necrosis | Altered Intercellular Communication | Major diagnostic pitfalls included obscuring acute inflammation, necrosis, tumor cells that mimicked benign cells with radiation/reactive atypia, and the under recognition of mucin-containing adenocarcinoma cells. | 19806643 |
| Inflammation, Erythema, Swelling, Pain Distress Question | Altered Intercellular Communication | In HA-treated patients, erythema and inflammation, swelling, and pain were most frequent. | 19807757 |
| Inflammation, Vasculitis, CTCAE, Congenital Abnormality | Altered Intercellular Communication | Furthermore, surgical manipulation in WG patients is associated with increased bony abnormalities and greater elevations of L-M scores, possibly because of worsening vasculitis and/or inflammation. | 19807982 |
| Inflammation, Chronic Kidney Diseases | Altered Intercellular Communication | Mineral metabolism and inflammation in chronic kidney disease patients: a cross-sectional study. | 19808245 |
| Inflammation, Abnormal metabolism, Chronic Kidney Diseases | Altered Intercellular Communication | Mineral metabolism abnormalities and inflammation are concerns in chronic kidney disease (CKD). | 19808245 |
| Inflammation, Chronic Kidney Diseases | Altered Intercellular Communication | Elevated serum P might play a role in the development of inflammation in CKD. | 19808245 |
| Inflammation, Heart failure, Metabolic Syndrome X | Altered Intercellular Communication | Metabolic syndrome, inflammation, and incident heart failure in the elderly: the cardiovascular health study. | 19808298 |
| Metabolic Syndrome X, ETV3 wt Allele, Congestive heart failure | Altered Intercellular Communication | Inflammation markers and metabolic syndrome (MetS) are associated with risk of congestive heart failure (CHF). | 19808298 |
| Inflammation, ETV3 wt Allele, Congestive heart failure | Altered Intercellular Communication | We evaluated whether combining inflammation markers and MetS provided additive information for incident CHF and if incorporating inflammation markers to the MetS definition added prognostic information. | 19808298 |
| Inflammation, ETV3 wt Allele, Congestive heart failure | Altered Intercellular Communication | MetS and elevated inflammation markers were independently associated with CHF risk (hazard ratios, 95% CI: 1.32, 1.16 to 1.51 for MetS; 1.53, 1.34 to 1.75 for CRP; 1.37, 1.19 to 1.55 for IL-6). | 19808298 |
| Inflammation, ETV3 wt Allele, Congestive heart failure | Altered Intercellular Communication | MetS and inflammation markers provided additive information on CHF risk in this elderly cohort. | 19808298 |
| ETV3 wt Allele | Altered Intercellular Communication | Inflammation-incorporated MetS definitions identified more participants with the same risk level as ATPIII MetS. | 19808298 |
| Inflammation, ETV3 wt Allele | Altered Intercellular Communication | Considering inflammation markers and MetS together may be useful in clinical and research settings. | 19808298 |
| Inflammation, Congestive heart failure | Altered Intercellular Communication | Inflammation may be a causative factor in congestive heart failure (CHF). | 19808373 |
| Brief Resilience Scale, Inflammation, Fibrosis Assessment, Hypertrophy | Altered Intercellular Communication | We retrospectively analyzed BrS biopsy samples from 21 unrelated patients for histopathologic abnormalities (hypertrophy, fibrosis, inflammation, fatty tissue) together with the patients' clinical, genetic, and imaging data. | 19808440 |
| Inflammation, Calcinosis | Altered Intercellular Communication | Relationships among regional arterial inflammation, calcification, risk factors, and biomarkers: a prospective fluorodeoxyglucose positron-emission tomography/computed tomography imaging study. | 19808576 |
| Arterial calcification, Plaque, Atherosclerotic | Altered Intercellular Communication | We explored how atherosclerotic plaque inflammation varies across arterial territories and how it relates to arterial calcification. | 19808576 |
| Inflammation, Vascular Diseases | Altered Intercellular Communication | We also tested the hypotheses that the degree of local arterial inflammation measured by PET is correlated with the extent of systemic inflammation and presence of risk factors for vascular disease. | 19808576 |
| Inflammation, Calcinosis | Altered Intercellular Communication | Calcification and inflammation rarely overlapped within arteries (carotid artery FDG uptake versus calcium score, r=-0.42, P=0.03). | 19808576 |
| Calcinosis, Plaque, Atherosclerotic | Altered Intercellular Communication | This study shows that FDG PET imaging can increase our knowledge of how atherosclerotic plaque inflammation relates to calcification, serum biomarkers, and vascular risk factors. | 19808576 |
| Inflammation, Calcinosis, Atherosclerosis | Altered Intercellular Communication | Plaque inflammation and calcification rarely overlap, supporting the theory that calcification represents a late, burnt-out stage of atherosclerosis. | 19808576 |
| Inflammation | Altered Intercellular Communication | Inflammation in one arterial territory is associated with inflammation elsewhere, and the degree of local arterial inflammation is reflected in the blood levels of several circulating biomarkers. | 19808576 |
| Inflammation | Altered Intercellular Communication | PDUS may be useful to detect at diagnosis the patients with most active inflammation who have a higher risk of relapses/recurrences. | 19808693 |
| Inflammation, Fatigue | Altered Intercellular Communication | Surgery-induced inflammation in relation to age, muscle endurance, and self-perceived fatigue. | 19808837 |
| Inflammation, Fatigue | Altered Intercellular Communication | Surgery-induced inflammation is related to reduced muscle endurance and the sensation of fatigue. | 19808837 |
| Flaked Material, Inflammation, Parakeratosis, Necrotic debris | Altered Intercellular Communication | Biopsies from confirmed EDS patients showed sloughing and flaking of superficial squamous epithelium with occasional bullous separation of the layers, parakeratosis, and varying degrees of acute or chronic inflammation. | 19809273 |
| Acute inflammation | Altered Intercellular Communication | Fungal elements were identified in 3 patients, but were not associated with acute inflammation. | 19809273 |
| Inflammation | Altered Intercellular Communication | Interestingly, the marker of chronic inflammation, IL-6, was positively associated with methylation of MGMT (P = 0.004), RARbeta (P = 0.002), and RASSF1A (P = 0.0081) as well as the total number of methylated genes (P < 0.0001), indicating the important role of IL-6 in maintaining promoter methylation of these genes. | 19809523 |
| Juvenile-Onset Still Disease | Altered Intercellular Communication | Adult-onset Still's disease (AOSD) is an uncommon inflammatory condition of unknown origin and pathogenesis. | 19809819 |
| Kidney Failure, Chronic, Inflammation | Altered Intercellular Communication | Our results confirm that ADMA and SDMA levels are increased in ESRD patients and suggest that a link may exist with inflammation and nutritional status. | 19809995 |
| Granuloma, Pleural Tuberculosis, Pleurisy, Comorbidity | Altered Intercellular Communication | Comparison of clinical, X-ray, laboratory, morphological, and immunological data in patients of the first (1978-1987) and second (1998-2007) periods has revealed the signs characteristic of the negative pathomorphism of the disease: progressive latency of tuberculous pleurisy and a lower Mantoux reaction, a lower detection rate for epithelioid giant-cell granulomas in the patients' biopsy specimens, a higher rate of pleural tuberculous inflammation, an increased frequency of comorbidity, a higher drug resistance rate in Mycobacterium tuberculosis, and decreased therapeutic efficiency. | 19810178 |
| Inflammation, Esophagitis | Altered Intercellular Communication | Endoscopy showed erosive cesophagitis on day 5 (D5) and ulcerated bleeding inflammation of the entire colon and rectum on D26. | 19810615 |
| Vasculitis, thromboembolic, Vasculitis of large artery | Altered Intercellular Communication | Activated circulating leukocytes and platelets could contribute to indolent vessel inflammation and possibly to thromboembolic events in patients with systemic large vessel vasculitis. | 19811309 |
| Inflammation, Hypertension, CTCAE | Altered Intercellular Communication | Hypertension, systemic inflammation and body weight in relation to lung function impairment-an epidemiological study. | 19811383 |
| Inflammation | Altered Intercellular Communication | Recent reports on the simultaneous occurrence of systemic inflammation and airflow obstruction are usually based on a highly selective patient population, but their importance warrants further evaluation in the general population. | 19811383 |
| Inflammation, Hypertension, CTCAE | Altered Intercellular Communication | Hypertension, BMI and systemic inflammation affect lung function independently of each other. | 19811383 |
| vascular inflammations | Altered Intercellular Communication | Higher levels of sRAGE in symptomatic patients may be markers of a higher degree of vascular inflammation in such patients. | 19811526 |
| vascular inflammations, Thrombosis, Atherosclerosis | Altered Intercellular Communication | Expression of inducible nitric oxide synthase (iNOS) is a marker of vascular inflammation which can result in thrombosis and atherosclerosis. | 19811579 |
| Inflammation, Neoplasms | Altered Intercellular Communication | The patient recovered well, and the primary tumor was resected after remission of the local inflammation. | 19811627 |
| Neurogenic Inflammation | Altered Intercellular Communication | The abundance of SP fibres around the human cerebral microvasculature, particularly post capillary venules, together with the changes observed following TBI in perivascular axons, cortical neurones and astrocytes suggest a potentially important role for substance P in neurogenic inflammation following human TBI. | 19812951 |
| Inflammation, Atherosclerosis | Altered Intercellular Communication | Although peroxisome proliferator-activated receptor (PPAR)gamma activation reduces inflammation and atherosclerosis, expression of PPARgamma in cells and its modulation by smoking are poorly investigated. | 19814730 |
| Pneumonitis | Altered Intercellular Communication | Long-term cigarette smoking is associated with pulmonary inflammation, but the acute effects of smoking have been less well studied. | 19816000 |
| Inflammation | Altered Intercellular Communication | Analysis of the exhaled breath condensate (EBC) can provide noninvasive markers that might be indicative of inflammation. | 19816000 |
| Inflammation | Altered Intercellular Communication | The reduced pH in chronic smokers shows cigarette-induced inflammation. | 19816000 |
| Airway structure, Asthma | Altered Intercellular Communication | The stability of airway inflammation in asthma over time is not known, yet this information is crucial to inflammation-based patient management. | 19816004 |
| Airway structure, Asthma | Altered Intercellular Communication | A cut point of 3% eosinophils should be used to distinguish eosinophilic from non-eosinophilic airway inflammation in asthma. | 19816004 |
| Post-Traumatic Stress Disorder, Inflammation | Altered Intercellular Communication | Inflammation might link posttraumatic stress disorder (PTSD) with an increased risk of cardiovascular events. | 19816056 |
| Post-Traumatic Stress Disorder, Inflammation | Altered Intercellular Communication | The findings provide further evidence for altered inflammation in PTSD. | 19816056 |
| Post-Traumatic Stress Disorder, Inflammation | Altered Intercellular Communication | Comorbid depressive symptoms ought to be considered to disentangle the unique associations of PTSD caused by MI and systemic inflammation. | 19816056 |
| Inflammation, Eosinophilic cystitis | Altered Intercellular Communication | Eosinophilic inflammation in the middle ear induces deterioration of bone-conduction hearing level in patients with eosinophilic otitis media. | 19816234 |
| Inflammation, Bacterial Infections | Altered Intercellular Communication | These findings suggest that not only bacterial infection but also eosinophilic inflammation in the middle ear may damage the inner ear. | 19816234 |
| Inflammation, Bone-conduction hearing aid | Altered Intercellular Communication | The present study was performed to determine whether eosinophilic inflammation is indeed related to deterioration of bone-conduction hearing level (BCHL). | 19816234 |
| Inflammation | Altered Intercellular Communication | Inflammation is associated with increased body mass and purportedly with increased size of adipose cells. | 19816674 |
| Inflammation | Altered Intercellular Communication | We sought to determine whether increased size of adipose cells is associated with localised inflammation in weight-stable, moderately obese humans. | 19816674 |
| Inflammation | Altered Intercellular Communication | The observed association between small adipose cells and inflammation may reflect impaired adipogenesis and/or terminal differentiation. | 19816674 |
| Inflammation | Altered Intercellular Communication | This question and whether small vs large adipose cells contribute differently to inflammation in adipose tissue are topics for future research. | 19816674 |
| Ischemia, Compression, Inflammation | Altered Intercellular Communication | This may result from compression, ischemia, inflammation, or metabolic and toxic etiologies. | 19817243 |
| Inflammation | Altered Intercellular Communication | Costochondritis, an inflammation of costochondral junctions of ribs or chondrosternal joints of the anterior chest wall, is a common condition seen in patients presenting to the physician's office and emergency department. | 19817327 |
| Degenerative polyarthritis, Inflammation | Altered Intercellular Communication | Its pathophysiology is marked by a gradual degenerative process accompanied by low-grade inflammation, and, although there is a strong correlation between age and OA risk, the abnormal changes that occur in the articular cartilage of people with OA differ notably from the typical changes associated with joint aging in several important ways. | 19817508 |
| APP gene, Inflammation, Apolipoprotein E, Aortic Aneurysm, Abdominal | Altered Intercellular Communication | Apolipoprotein E (ApoE) genotype has been associated with systemic inflammation and athero-thrombosis however the association with abdominal aortic aneurysm (AAA) has not been previously examined. | 19818961 |
| Vascular Diseases, Malnutrition, Inflammation | Altered Intercellular Communication | Furthermore, serum albumin is paradoxically linked to vascular disease under conditions both of overnutrition and of malnutrition and inflammation complex. | 19819455 |
| Inflammation, Helicobacter-associated gastritis | Altered Intercellular Communication | The number of Tregs was elevated in H. pylori-associated gastritis, where it was positively correlated with the grade of chronic inflammation and the number of lymphoid follicles. | 19819643 |
| Inflammation, Acute Coronary Syndrome | Altered Intercellular Communication | Acute decline in renal function, inflammation, and cardiovascular risk after an acute coronary syndrome. | 19820133 |
| Heart Diseases, Inflammation | Altered Intercellular Communication | The prognostic significance of worsening renal function has also been shown in various cohorts of cardiac disease; however, the predictors of worsening renal function and the contribution of inflammation remains to be established. | 19820133 |
| Inflammation, Kidney Diseases | Altered Intercellular Communication | CRP is an independent predictor for subsequent decline in renal function and reinforces the idea that inflammation may be related to the pathophysiology of progressive renal disease. | 19820133 |
| Pancreatitis | Altered Intercellular Communication | There was a significant correlation between CT and MR gradings for pancreatic or peripancreatic inflammation (r = 0.688, P < 0.01). | 19820487 |
| Exanthema, Weakness, Heliotropium europaeum, Myositis, Dermatomyositis | Altered Intercellular Communication | Dermatomyositis is an unknown cause's disease that in general is characterized by muscular inflammation with weakness and typical skin rash (heliotrope and Gottron's papules). | 19820679 |
| Acute respiratory failure, Oliguria | Altered Intercellular Communication | Highest basal comorbility of patients, oliguria and malnutrition-inflammation dates are princess prognosis and mortality factors in ARF today A new approach is needed in ARF because this new type/class of population. | 19820755 |
| Inflammation | Altered Intercellular Communication | Oxidative stress and a subclinical inflammation are crucial factors in its development. | 19820759 |
| Inflammatory abnormality of the eye, Uveitis | Altered Intercellular Communication | Involvement of the cornea endothelium during uveitis has not been extensively studied even though it might participate in or constitute a target of ocular inflammation. | 19820783 |
| Structure of gastroduodenal artery, Plaque, Amyloid, Amyloidosis | Altered Intercellular Communication | This is the first case report of RA-related systemic reactive AA amyloidosis histopathologically demonstrating rapid regression of amyloid deposits on gastroduodenal mucosa after adequate suppression of the underlying inflammatory condition. | 19820941 |
| Inflammation | Altered Intercellular Communication | Involvement of chronic inflammation in methylation induction was suggested. | 19821005 |
| Refractory anemias, Inflammation, deformities qualifier, Fracture | Altered Intercellular Communication | The generalized effect of inflammation on bone may result in a decreased quality of bone and is associated with an increased risk of fractures and deformities, both in RA and AS. | 19822048 |
| Shock, Failure, Spinal Fractures | Altered Intercellular Communication | Bone fragility is also due to changes in structural properties resulting from inflammation-induced bone failure in the spine in combination with reduced capacity of shock absorption leading to vertebral fractures. | 19822048 |
| Refractory anemias, Inflammation, Degenerative polyarthritis | Altered Intercellular Communication | This study was carried out to analyze the expression of Netrins and their receptors in synovial cells of patients with RA, OA, and control subjects without synovial inflammation. | 19822088 |
| Disease, Inflammation, Traumatic injury, Malignant Neoplasms | Altered Intercellular Communication | The most common etiological factors of this syndrome include diseases or trauma of the central nervous system and malignant tumor or inflammation of the lung. | 19822501 |
| Inflammation, Biliary calculi, Virus Diseases, Alcohol abuse, Traumatic injury | Altered Intercellular Communication | The pancreas reacts by enzymatic autodigestion and inflammation to external and internal factors: alcohol abuse, trauma, biliary stones, and viral infections. | 19822503 |
| Pancreatitis | Altered Intercellular Communication | The diffuse spread of pancreatic inflammation may form a retroperitoneal phlegmon. | 19822503 |
| Inflammation, Adenoma | Altered Intercellular Communication | Changes in inflammation markers were not associated with adenoma recurrence. | 19822838 |
| Inflammation, Adenoma of large intestine | Altered Intercellular Communication | Nevertheless, inflammation markers do not mediate the chemopreventive effect of aspirin on colorectal adenomas. | 19822838 |
| Inflammation, Neoplasms | Altered Intercellular Communication | Univariate analysis revealed that significant prognostic factors for poorer survival were male gender (P = 0.026), age older than 65 years (P = 0.013), the presence of inflammation (P = 0.009), moderately or poorly differentiated tumor (P < 0.001), nonpolypoid gross type (P = 0.003), and pT stage (P < 0.001). | 19823903 |
| Inflammation, Coronary Artery Disease | Altered Intercellular Communication | The common variant in the GSTM1 and GSTT1 genes is related to markers of oxidative stress and inflammation in patients with coronary artery disease: a case-only study. | 19823950 |
| Inflammation | Altered Intercellular Communication | There was an increased exposure of the markers MMP-9 and MMP-2, which was most evident in the fundal GM and correlated with the activity of inflammation. | 19824429 |
| Refractory anemias, Inflammation, NLRP3 gene, Degenerative polyarthritis | Altered Intercellular Communication | The NALP3 inflammasome activity does not account for the difference in level of inflammation between RA and osteoarthritis. | 19824913 |
| Inflammation | Altered Intercellular Communication | MRI of the AC joint showed inflammation and erosion with joint fluid. | 19826815 |
| Inflammation | Altered Intercellular Communication | Significant contrast enhancement was noted at the SC joint due to inflammation. | 19826815 |
| Inflammation, Enteral | Altered Intercellular Communication | Enteric fluids produced by enterocutaneous fistulae can cause severe inflammation in the surrounding skin. | 19827481 |
| Inflammation | Altered Intercellular Communication | Endoscopic signs of inflammation, its extent and severity were recorded. | 19827530 |
| Inflammation, Urinary tract infection | Altered Intercellular Communication | Blood examination and urinalysis showed neither systemic inflammation nor urinary tract infection. | 19827624 |
| Inflammation | Altered Intercellular Communication | In addition, the results strongly suggest that the cytokines released by activated lymphocytes at sites of inflammation may play a part in up-regulating CD81 expression. | 19828092 |
| Hepatic necrosis, Inflammation, Fatty degeneration | Altered Intercellular Communication | In the liver, hepatic necrosis was observed with fatty degeneration accompanied by inflammation. | 19828353 |
| Shock, Inflammation, Shock, Hemorrhagic | Altered Intercellular Communication | Excessive autolytic inflammation accompanied by dysfunction of "shock organs" is recognized as arising from hemorrhagic shock due to the promotion of endovascular recruitment of neutrophils. | 19828355 |
| Inflammation, Inflammatory disorder, Metabolic Syndrome X | Altered Intercellular Communication | This suggests that replacement of dietary SFA with MUFA could prevent adipose tissue inflammation and may reduce the risk of inflammation-related diseases such as metabolic syndrome. | 19828712 |
| Inflammation, "Alzheimers Disease", Data types - Address | Altered Intercellular Communication | Upon activation by calcineurin, the nuclear factor of activated T-cells (NFAT) translocates to the nucleus and guides the transcription of numerous molecules involved in inflammation and Ca(2+) dysregulation, both of which are prominent features of Alzheimer's disease (AD). | 19828810 |
| Inflammation, Bladder Neoplasm, Necrosis | Altered Intercellular Communication | Perivesical inflammation and necrosis due to mitomycin C instillation after transurethral resection of bladder tumor: we must be vigilant! | 19829042 |
| Inflammation, glucose metabolism, Hyperglycemia, Electrocardiogram: myocardial infarction (finding), Diabetes Mellitus, Myocardial | Altered Intercellular Communication | In 175 consecutive patients without previously known diabetes and with ST elevation myocardial infarction treated with primary angioplasty, we evaluated the relation between acute and chronic glucose dysmetabolism and early and late mortality and the relation between hyperglycemia and extension of myocardial damage [creatine phosphokinase-MB (CPK-MB), troponin I levels, ejection fraction], inflammation (leukocyte count, erythrocyte sedimentation rate, C-reactive protein) and prognostic biohumoral markers [N-terminal brain natriuretic peptide (NT-proBNP) and lactic acid]. | 19829142 |
| Inflammation, Synovitis, Acne, Pustulosis, Hyperostosis, and Osteitis Syndrome, Hypertrophy | Altered Intercellular Communication | Spinal specimens obtained surgically showed nonspecific inflammation and fibrous hypertrophy of the bone marrow, confirming a diagnosis of the SAPHO syndrome. | 19830381 |
| Primary malignant neoplasm | Altered Intercellular Communication | HsCRP increased in response to RT for H&N cancer as a sign of irradiation-induced inflammation. | 19830461 |
| Inflammation, Prostate carcinoma | Altered Intercellular Communication | African American men have the highest rates of prostate cancer worldwide, and immunogenetic studies suggest that people of African descent have increased susceptibility to diseases of inflammation. | 19830784 |
| Inflammation, Prostate carcinoma | Altered Intercellular Communication | Since genetic susceptibility is an etiological factor in prostate cancer, we hypothesize that sequence variants in the promoter region of the CD14 gene that regulate inflammation may modify individual susceptibility to this disease. | 19830784 |
| Inflammation, Periodontal Diseases, Gingival Hemorrhage, Dental Plaque, Hematological Disease | Altered Intercellular Communication | Oral hygiene motivation and dental plaque control is crucial in order to prevent gingival bleeding, inflammation and severe periodontal diseases in patients with haematologic disorders. | 19832917 |
| Inflammation, Diabetes Mellitus | Altered Intercellular Communication | Risk factors included luminal stenosis, age, smoking, diabetes, calcium-phosphorus product, inflammation, and kidney function. | 19833908 |
| Refractory anemias, Rheumatoid Arthritis, Inflammation | Altered Intercellular Communication | Fluorodeoxyglucose (FDG) uptake in joint lesions in patients with rheumatoid arthritis (RA) reportedly represents the degree of synovial inflammation. | 19834653 |
| Refractory anemias, Inflammation | Altered Intercellular Communication | Whole-body FDG-PET/CT delineated large-joint lesions in patients with RA, and the metabolic activity of inflammation was accurately overlaid on the joint anatomy. | 19834653 |
| Inflammation, Cardiac dysfunction | Altered Intercellular Communication | In addition, TnTc levels are significantly associated with cardiac dysfunction (p < 0.05) and inflammation (p 0.01). | 19835288 |
| Inflammation, Cardiac dysfunction, Ventricular Dysfunction, Left | Altered Intercellular Communication | The causes of elevated cTnT levels in hemodialysis patients was multiple: cardiac dysfunction, left ventricular dysfunction and inflammation. | 19835288 |
| Inflammation, Chronic inflammatory disorder | Altered Intercellular Communication | Given this role for proteasome in inflammation resolution, restoration of proteasome function may constitute a novel mechanism for intervening in chronic inflammatory diseases. | 19835847 |
| Inflammation, Atherosclerosis, Cardiovascular Diseases | Altered Intercellular Communication | Given that inflammation (characterized here by CRP) is an important factor in the development of atherosclerosis and cardiovascular disease, these results suggest a role for OH-PAHs in the progression of atherosclerosis. | 19836015 |
| Presenile dementia, Inflammation | Altered Intercellular Communication | Inflammation is believed to play a pivotal role in dementia, but its role is still unclear. | 19836632 |
| Presenile dementia, Inflammation | Altered Intercellular Communication | The aim of our study was to analyze the interplay among markers of inflammation, such as fibrinogen and high CRP levels, and dementia. | 19836632 |
| Presenile dementia, Inflammation | Altered Intercellular Communication | First, we performed a cross-sectional study comparing markers of inflammation between 99 patients affected by dementia (mean age: 83.0+/-0.6 years) and 99 controls (mean age: 83.9+/-0.7 years). | 19836632 |
| Inflammation, Dementia, Vascular, Presenile dementia, "Alzheimers Disease", Data types - Address, VAD I protocol | Altered Intercellular Communication | Then, we analyzed the relationship between inflammation and dementia in the same population composed by 34 Alzheimer's disease (AD) patients (mean age: 83.4+/-0.8 years), 64 vascular dementia (VaD) patients (mean age: 82.7+0.8 years) and 99 controls. | 19836632 |
| Inflammation, Data types - Address | Altered Intercellular Communication | The study suggests that inflammation may have a pathogenetic role in AD. | 19836632 |
| Airway structure, Nasal Polyps | Altered Intercellular Communication | Respiratory symptoms without BHR were associated with eosinophilic airway inflammation and increased ENO only in patients with nasal polyps. | 19837820 |
| Inflammation, Graft-vs-Host Disease | Altered Intercellular Communication | T-regs were positively correlated with both inflammation and aGVHD grade. | 19838066 |
| Inflammation, Graft-vs-Host Disease | Altered Intercellular Communication | Twelve cases with low T-regs had mild inflammation and lower grades of aGVHD and 6 cases with high T-regs had dense inflammatory infiltrate and higher grades of aGVHD. | 19838066 |
| Inflammation, Graft-vs-Host Disease | Altered Intercellular Communication | In aGVHD of the skin, T-regs increased with the degree of inflammation and GVHD grade. | 19838066 |
| Inflammation | Altered Intercellular Communication | Interleukins are important mediators and modulators of inflammation. | 19838108 |
| Granulomatous inflammation | Altered Intercellular Communication | On physical examination, hyperpigmented, papular lesions were noticed; biopsy of the skin of his right elbow showed granulomatous inflammation. | 19838983 |
| Inflammation | Altered Intercellular Communication | In patients with intact cag-PAI, acute on chronic inflammation was present in 25 (81%) and was more common than chronic inflammation (P=0.013). | 19839224 |
| Inflammation | Altered Intercellular Communication | The cagAP region was significantly associated with GC (n=12 [80%], P<0.001) and GU (n=9 [82%], P=0.001) compared to NUD (n=24 [30%] and with significant acute on chronic inflammation (n=40 [80%], P=0.007). | 19839224 |
| Necrotizing granulomatous inflammation, Granulomatosis with polyangiitis, physiopathological | Altered Intercellular Communication | Necrotizing granulomatous inflammation of the upper respiratory tract is one of the hallmarks of Wegener's granulomatosis (WG), which may explain the reason for olfactory dysfunction in WG. | 19839246 |
| Granulomatous inflammation, Failure (biologic function) | Altered Intercellular Communication | In general, a cautious attitude prevails out of fear of complications or failure due to the underlying granulomatous inflammation. | 19839261 |
| Inflammation, Malnutrition | Altered Intercellular Communication | Because malnutrition and inflammation can cause high mortality in MHD patients, preserving RRF is important for these patients. | 19839818 |
| Inflammation, hepcidin, Prohepcidin | Altered Intercellular Communication | Hyporesponsiveness to erythropoietin therapy in hemodialyzed patients: potential role of prohepcidin, hepcidin, and inflammation. | 19839848 |
| Inflammation, Overweight | Altered Intercellular Communication | Inflammation and overweight in peritoneal dialysis: is there an association? | 19839849 |
| Inflammation | Altered Intercellular Communication | Our findings confirm the relationship between inflammation, body fat, and immunocompetence, which may be superimposed potentializing the inflammatory status. | 19839849 |
| Inflammation | Altered Intercellular Communication | The degree of inflammation (NOSPECS Class 2) decreased (P<0.001). | 19839884 |
| Autoimmune Diseases, Blepharitis, Thyroid associated opthalmopathies | Altered Intercellular Communication | Can autoimmunity against calsequestrin explain the eye and eyelid muscle inflammation of thyroid eye disease? | 19839885 |
| Inflammation, Hemorrhage | Altered Intercellular Communication | A biopsy from an elevated conjunctival area showed a brown pigmentation to be haemosiderin and haemogranulomatous inflammation most probably due to recurrent subconjunctival haemorrhage. | 19839907 |
| Inflammation, Electrocardiogram: myocardial infarction (finding) | Altered Intercellular Communication | Markers of inflammation have been associated with risk of myocardial infarction (MI). | 19841382 |
| Interstitial lung fibrosis, Inflammation | Altered Intercellular Communication | Chemokine receptors in a regulation of interstitial lung fibrosis and inflammation. | 19842835 |
| Airway structure | Altered Intercellular Communication | Neutrophils may contribute significantly to airway inflammation in certain asthma subtypes. | 19842845 |
| Necrotizing inflammation | Altered Intercellular Communication | Necrotizing inflammation is more often seen in patients with low CD4 counts. | 19843144 |
| Inflammation, Metabolic Syndrome X, Diabetes Mellitus, Heart Diseases, Overweight | Altered Intercellular Communication | The ability to reduce inflammation in overweight and obese individuals may be valuable in preventing the progression to metabolic syndrome with associated risks for heart disease and diabetes. | 19843321 |
| Airway structure, Bronchiectasis | Altered Intercellular Communication | Chest CT revealed diffuse airway inflammation with bronchiectasis. | 19843409 |
| Inflammation, Pain, Postoperative | Altered Intercellular Communication | Although opioids are the mainstay of inpatient postoperative pain management, they do not block inflammation. | 19843482 |
| Tears body substance, Inflammatory abnormality of the eye, Disorder of eye | Altered Intercellular Communication | Ocular surface inflammation, and nerve growth factor level in tears in active thyroid-associated ophthalmopathy. | 19844736 |
| Inflammatory abnormality of the eye | Altered Intercellular Communication | Tear NGF may have a specific role in ocular surface inflammation, which protects against ocular surface damage in patients with active TAO. | 19844736 |
| Inflammation, Dental Leakage | Altered Intercellular Communication | The pelvic drain was always effective in allowing the early diagnosis of leakages and limiting the spread of peritoneal inflammation. | 19845262 |
| Inflammation, Urticaria | Altered Intercellular Communication | Coagulation/fibrinolysis and inflammation markers are associated with disease activity in patients with chronic urticaria. | 19845571 |
| Inflammation, curcumin | Altered Intercellular Communication | In this article, we studied the coagulation/fibrinolysis and inflammation markers and their relationship to disease activity in patients with CU. | 19845571 |
| Eosinophilic disorder, Inflammation | Altered Intercellular Communication | Eosinophilia is an established marker of asthma-related inflammation. | 19846286 |
| Inflammation | Altered Intercellular Communication | The high expression of MCP-1 and IL-8 chemokines suggest that macrophages and T cells may stimulate inflammation of the CNS in MFS. | 19846311 |
| Inflammation, Negative Regulation of Cell Cycle | Altered Intercellular Communication | Global gene expression analyses of tetraploid endothelial cells revealed a dysfunctional phenotype characterized by a cell cycle arrest profile (decreased CCNE2/A2, RBL1, BUB1B; increased CDKN1A) and increased expression of genes involved in inflammation (IL32, TNFRSF21/10C, PTGS1) and extracellular matrix remodeling (COL5A1, FN1, MMP10/14). | 19846757 |
| Inflammation, Malignant Neoplasms | Altered Intercellular Communication | These increases were not found in PP.Rhythmical behavior of blood flow in malignant tumors is totally different from that in regions with inflammation. | 19847053 |
| Diabetic Angiopathies, Chronic Kidney Diseases | Altered Intercellular Communication | These findings need to be underlined if we consider that chronic renal failure is an inflammatory condition and this research furtherly supports literature data regarding the role of activated leukocytes in the development of the vascular complications. | 19847059 |
| Inflammation, Periodontitis, Alveolar Bone Loss, Cerebrovascular accident | Altered Intercellular Communication | We evaluated incidence of cerebrovascular events consistent with stroke or transient ischemic attack in relation to mean radiographic alveolar bone loss (a measure of periodontitis history) and cumulative periodontal probing depth (a measure of current periodontal inflammation). | 19847898 |
| Cerebrovascular Disorders | Altered Intercellular Communication | These results support an association between history of periodontitis-but not current periodontal inflammation-and incidence of cerebrovascular disease in men, independent of established cardiovascular risk factors, particularly among men aged <65 years. | 19847898 |
| Communicable Diseases, Fibrosis Assessment, Inflammation | Altered Intercellular Communication | CXCR3-associated chemokines CXCL9-CXCL11 promote histologic progression in chronic hepatitis C virus (HCV) infection, as indicated by elevated intrahepatic levels of messenger RNA in patients with advanced inflammation and fibrosis. | 19848607 |
| Fibrosis Assessment, Intrahepatic Route of Drug Administration | Altered Intercellular Communication | Expression of all 3 chemokines, when analyzed as a group, was significantly associated with intrahepatic inflammation and fibrosis. | 19848607 |
| Inflammation, Fibrosis Assessment | Altered Intercellular Communication | Plasma levels of CXCL10 were significantly elevated in patients with advanced fibrosis, whereas CXCL9 levels were significantly elevated in patients with advanced inflammation. | 19848607 |
| Inflammation, Fibrosis Assessment | Altered Intercellular Communication | By proportional odds multivariate modeling, we observed an association between fibrosis and CXCL10 (P< .002) as well as between fibrosis and inflammation (P<.001). | 19848607 |
| Dermatitis, Atopic, Inflammation, Data types - Address | Altered Intercellular Communication | Background A significant proportion of young children with atopic dermatitis (AD) is sensitized to microbial allergens, which play a potential role in the pathogenesis of AD inflammation. | 19849698 |
| Diastolic dysfunction, Inflammation | Altered Intercellular Communication | This study demonstrates progressive increases in markers of collagen turnover and inflammation in HFPSF with diastolic dysfunction. | 19850207 |
| Inflammation, Prediabetes syndrome, Diabetes Mellitus, Non-Insulin-Dependent | Altered Intercellular Communication | Gender differences in adiponectin and low-grade inflammation among individuals with normal glucose tolerance, prediabetes, and type 2 diabetes. | 19850242 |
| Inflammation, Restenosis | Altered Intercellular Communication | Because inflammation plays a key role in restenosis, pimecrolimus, an anti-inflammatory drug, might reduce restenosis without adversely affecting re-endothelialization. | 19850264 |
| Inflammation, Neutrophilia (finding) | Altered Intercellular Communication | Pivotal Advance: Pharmacological manipulation of inflammation resolution during spontaneously resolving tissue neutrophilia in the zebrafish. | 19850882 |
| Inflammation, Thrombosis, Primary malignant neoplasm | Altered Intercellular Communication | Prostanoids play a critical role in clinical areas such as inflammation, thrombosis, immune response, and cancer. | 19850905 |
| Inflammation, Dilated Cardiomyopathy Pathway, Heart failure | Altered Intercellular Communication | Using a Cre/loxP system, we disrupted the Nemo gene in a cardiomyocyte-specific manner in the heart, which simulated gene expression changes underlying human heart failure and caused adult-onset dilated cardiomyopathy accompanied by inflammation and apoptosis. | 19850942 |
| Inflammation, Atherosclerosis | Altered Intercellular Communication | The chemokine and adhesion molecule fractalkine and its receptor CX(3)CR1 have emerged as interesting regulators in inflammation and related atherosclerosis. | 19851523 |
| Inflammation, Postprandial hyperlactemia | Altered Intercellular Communication | Postprandial hyperlipemia may influence inflammation; thus, we investigated fractalkine levels four and eight hours after inducing postprandial hyperlipemia. | 19851523 |
| Inflammation, Aortic Valve Stenosis | Altered Intercellular Communication | The presence of five pathogens was assessed, together with a possible correlation of the total pathogen burden on inflammation and (auto)immunity in aortic stenosis (AS) and degenerative aortic valve bioprosthesis (BP). | 19852145 |
| Inflammation, Nucleolar Fibrillar Material | Altered Intercellular Communication | In the majority of degenerative aortic valves, specific pathogens, inflammation and immunity were localized predominantly in the fibrosa of AS patients, and in superficial regions of the BP. | 19852145 |
| Inflammation | Altered Intercellular Communication | The presence of inflammation and the duration of dialysis treatment contribute to this complication. | 19852148 |
| Inflammation, Congestion, Edema | Altered Intercellular Communication | Archival nasal tissue samples were collected and examined by light microscopy: the number of goblet cells was counted, and the degree of inflammation, congestion, and edema was graded as mild, moderate, or severe. | 19852553 |
| Refractory anemias, Rheumatoid Arthritis, Inflammation | Altered Intercellular Communication | Rheumatoid arthritis (RA) is characterized by high cardiovascular (CV) mortality, which has been related to systemic inflammation. | 19852912 |
| Inflammation, Bipolar Disorder | Altered Intercellular Communication | Previous studies have demonstrated increased levels of serum markers of systemic inflammation and immune system function among individuals with depressive symptoms. | 19853625 |
| Airway structure, Sleep Apnea, Obstructive, Traumatic injury, Osage language | Altered Intercellular Communication | Hypoxia and snoring-related mechanical trauma contribute to airway inflammation in obstructive sleep apnoea (OSA). | 19854036 |
| Airway structure, Osage language | Altered Intercellular Communication | Increased exhaled nitric oxide (FENO), an airway inflammation marker, has been reported in OSA patients. | 19854036 |
| Pharyngitis, Osage language | Altered Intercellular Communication | We propose the measure of NO in the oral cavity (oNO) as marker of oropharyngeal inflammation in OSA. | 19854036 |
| Inflammation, Hypoxemia, Osage language | Altered Intercellular Communication | The finding that oral NO is increased in OSA and is related to upper airway obstructive episodes and to hypoxemia severity, strengthens the clinical and pathogenic role of oral inflammation in OSA. | 19854036 |
| Airway structure, ARCN1 gene, Pulmonary Emphysema | Altered Intercellular Communication | Systemic and airway inflammation and the presence of emphysema in patients with COPD. | 19854037 |
| Inflammation, Cardiovascular Diseases | Altered Intercellular Communication | Aging is associated with increasing levels of systemic inflammation and oxidative stress, both of which contribute to the progression of cardiovascular disease. | 19854376 |
| Inflammation, Aggressive behavior, Pneumonitis, Blood Coagulation Disorders | Altered Intercellular Communication | ALI/ARDS is the response of the lung to a local or systemic aggression, resulting in local inflammation and coagulation disorders, which lead to increased inflammatory pulmonary edema. | 19854543 |
| Inflammation, Systemic disease | Altered Intercellular Communication | This study suggests that CRP is not a predictive marker of inflammation and peripheral endothelial dysfunction in XFS, which is accepted as a systemic disorder. | 19855290 |
| Communicable Diseases, Inflammation, Leukocytosis | Altered Intercellular Communication | Additional examinations revealed the following markers of inflammation: leukocytosis (11 G/I) with normal level of eosinophils, CRP > 0.6 mg/I, ESR 120 mm/h, and IgG 20 g/l, without any source of infection. | 19856878 |
| Inflammation, Venous Thromboembolism, vinyltriethoxysilane | Altered Intercellular Communication | Elevated platelet count might reflect increased inflammation as an etiological factor for venous thromboembolism (VTE). | 19857046 |
| Inflammation, vinyltriethoxysilane, Fatigue | Altered Intercellular Communication | Poor sleep, fatigue, and exhaustion are all associated with inflammation and are also common sequelae of chronic psychological stress that previously predicted increased risk of VTE. | 19857046 |
| Papillary thyroid carcinoma, Laryngeal Squamous Cell Carcinoma, Necrotizing, Squamous cell carcinoma, metastatic | Altered Intercellular Communication | Incidental papillary thyroid carcinoma and necrotizing granulomatous inflammation were found in addition to squamous cell carcinoma metastasis in the pathological study of the neck dissection specimen in a 70-year-old male patient with laryngeal squamous cell carcinoma. | 19857198 |
| Inflammation, Endothelial dysfunction, Hyperuricemia | Altered Intercellular Communication | Hyperuricemia is a mediator of endothelial dysfunction and inflammation in renal allograft recipients. | 19857674 |
| Proteinuria, Inflammation, Diabetes Mellitus, Abnormal renal function, Obesity | Altered Intercellular Communication | Exclusion criteria were abnormal renal function, proteinuria, diabetes mellitus, obesity, and inflammation. | 19857674 |
| Inflammation, Endothelial dysfunction | Altered Intercellular Communication | Concentrations of plasma resistin, CD146, and soluble vascular cell adhesion molecule-1 (sVCAM-1), which are markers of endothelial dysfunction and inflammation, were assessed in both groups. | 19857674 |
| Inflammation, Endothelial dysfunction, Hyperuricemia | Altered Intercellular Communication | Hyperuricemia mediates endothelial dysfunction and inflammation and via this pathway, possibly contributes to chronic allograft injury and cardiovascular events in renal allograft recipients. | 19857674 |
| Inflammation, Cardiac Arrhythmia, Atrial Fibrillation by ECG Finding | Altered Intercellular Communication | Relationship of indices of inflammation and thrombogenesis to arrhythmia burden in paroxysmal atrial fibrillation. | 19858230 |
| Inflammation, Alveolar Epithelial Cells | Altered Intercellular Communication | The best performing biomarkers were the neutrophil chemotactic factor, IL-8, and SP-D, a product of alveolar type 2 cells, supporting the concept that acute inflammation and alveolar epithelial injury are important pathogenetic pathways in human ALI/ARDS. | 19858233 |
| Inflammation, Alveolar Epithelial Cells | Altered Intercellular Communication | From a pathogenesis perspective, the degree of acute inflammation and alveolar epithelial injury are highly associated with the outcome of human ALI/ARDS. | 19858233 |
| Inflammation, Myopathy | Altered Intercellular Communication | Muscle biopsy demonstrated severe generalised necrotising myopathy in the notable absence of inflammation. | 19859711 |
| Inflammation, Giant Cells, Foreign-Body | Altered Intercellular Communication | Histological examination showed foreign body material surrounded by chronic inflammation, foreign body-type multinucleated giant cells, extravasated red blood cells and fibroblastic proliferation. | 19860134 |
| Inflammation, Abdominal Abscess | Altered Intercellular Communication | Because severe intraperitoneal inflammation was observed, ilectomy was changed to drainage of intra-abdominal abscess. | 19860242 |
| Cholecystitis, Biliary calculi | Altered Intercellular Communication | Sulbactam/cefoperazone was started under a tentative diagnosis of gall bladder inflammation with gallstones based on ultrasonographic findings. | 19860259 |
| Inflammation, Necrosis | Altered Intercellular Communication | Histopathologic examination showed acinar cell necrosis and dense inflammation of the affected minor salivary glands in the second biopsy. | 19860638 |
| Inflammation | Altered Intercellular Communication | Telomere length reflects lifetime cumulative oxidative stress from environmental exposures, such as cigarette smoking and chronic inflammation. | 19861514 |
| Inflammation, Stomach Carcinoma | Altered Intercellular Communication | Chronic inflammation has been implicated in the etiology of gastric cancer. | 19861525 |
| Inflammation | Altered Intercellular Communication | Prostaglandin E(2) (PGE(2)) is one of the major end-products of the cyclooxygenase-2 pathway, an enzyme that is an important mediator of inflammation. | 19861525 |
| Inflammation, Stomach Carcinoma | Altered Intercellular Communication | Our findings suggest that higher levels of urinary PGE-M, a marker of inflammation, may be associated with gastric cancer risk. | 19861525 |
| Communicable Diseases, Inflammation, Traumatic injury, Neoplasms | Altered Intercellular Communication | The secondary acquired obstructions may result from infection, inflammation, neoplasm, trauma or mechanical causes. | 19861752 |
| Heart Diseases, HD Term Type, Inflammation | Altered Intercellular Communication | Heart disease (HD) can stress the alveolar blood-gas barrier, resulting in parenchymal inflammation and remodeling. | 19862572 |
| Inflammation, Fibrosis Assessment, viral hepatitis E infection | Altered Intercellular Communication | To evaluate the clinical practical value of apparent diffusion coefficient (ADC) measurements based on diffusion-weighted MR imaging (DWI) for quantification of liver fibrosis and inflammation for hepatitis viral infection. | 19862980 |
| Inflammation, Fibrosis Assessment | Altered Intercellular Communication | The inflammation grades and fibrosis stages were evaluated histologically by biopsy. | 19862980 |
| Inflammation | Altered Intercellular Communication | There was weak to moderate negative correlation between ADCs and inflammation grade. | 19862980 |
| Inflammation, Fibrosis Assessment | Altered Intercellular Communication | The DWI measurement of hepatic ADC can be used to quantify liver fibrosis and inflammation. | 19862980 |
| Inflammation, Lung Diseases, Obstructive | Altered Intercellular Communication | Inflammation has been identified as an important factor for disease exacerbation in obstructive lung disease. | 19863191 |
| hearing impairment, Inflammation | Altered Intercellular Communication | The pure-tone audiogram (PTA) indicated mild hearing loss in the right ear, and her hearing continued to deteriorate despite recovery from inflammation. | 19864094 |
| Pneumonitis | Altered Intercellular Communication | Vaccination to induce antibodies blocking the CX3C-CX3CR1 interaction of respiratory syncytial virus G protein reduces pulmonary inflammation and virus replication in mice. | 19864390 |
| Weight decreased, Pneumonitis | Altered Intercellular Communication | The results show that mice vaccinated with G protein peptides or polypeptides containing the CX3C motif generate antibodies that inhibit G protein CX3C-CX3CR1 binding and chemotaxis, reduce lung virus titers, and prevent body weight loss and pulmonary inflammation. | 19864390 |
| Inflammation | Altered Intercellular Communication | IMAT was primarily related to age and total body adiposity; subclinical inflammation in fat significantly contributes to IMAT. | 19864639 |
| Inflammation | Altered Intercellular Communication | Both patients had active H. pylori-related inflammation. | 19864985 |
| Inflammation, Central Nervous System Agents | Altered Intercellular Communication | In animals, central nervous system inflammation increases drug accumulation in the brain partly due to a loss of central nervous system drug efflux transporter function at the blood-brain barrier. | 19865006 |
| Inflammation, Brain Injuries | Altered Intercellular Communication | Our results suggest that central nervous system inflammation following acute brain injury may selectively inhibit the activity of specific drug efflux transporters within the blood-brain barrier. | 19865006 |
| Presenile dementia, Impaired cognition | Altered Intercellular Communication | Our results indicate that: i) consistent with recent neuropathological findings, gene expression changes associated with cognitive impairment in oldest-old persons are distinct from those in cognitively impaired youngest-old persons; ii) transcripts affected in young-old subjects with dementia participate in biological pathways related to synaptic function and neurotransmission while transcripts affected in oldest-old subjects with dementia are associated with immune/inflammatory function; iii) upregulation of immune response genes in cognitively intact oldest-old subjects and their subsequent downregulation in dementia suggests a potential protective role of the brain immune-associated system against dementia in the oldest-old; iv) consistent with gene expression profiles, protein expression of several selected genes associated with the inflammatory/immune system in inferior temporal cortex is significantly increased in cognitively intact oldest-old persons relative to cognitively intact young-old persons, but impaired in cognitively compromised oldest-old persons relative to cognitively intact oldest-old controls. | 19865478 |
| Presenile dementia | Altered Intercellular Communication | These results suggest that disruption of the robust immune homeostasis that is characteristic of oldest-old individuals who avoided dementia may be directly associated with dementia in the oldest-old and contrast with the synaptic and neurotransmitter system failures that typify dementia in younger old persons. | 19865478 |
| Orbital Pseudotumor | Altered Intercellular Communication | Thirty to sixty percent of patients also suffer from orbital inflammation. | 19865824 |
| Inflammation, Silicosis, Pulmonary Fibrosis | Altered Intercellular Communication | Chronic occupational exposure to tiny particles of silicon dioxide can stimulate parenchymal inflammation, collagen synthesis and, ultimately pulmonary fibrosis called silicosis. | 19866335 |
| Inflammation, Structure of posterior cerebral artery | Altered Intercellular Communication | Therefore, we hypothesized that leukocytes associated with either acute or chronic inflammation attracted to the prostate consequent to aging or tumorigenesis may promote the abnormal cellular proliferation associated with BPH and PCa. | 19866464 |
| Inflammation, Atherosclerosis | Altered Intercellular Communication | Inflammation is involved in the development of atherosclerosis. | 19874552 |
| Inflammation, Vascular Diseases, Atherosclerosis | Altered Intercellular Communication | The CC chemokine receptor 5 (CCR5) initiates chemotaxis and modulates the inflammation secondary to atherosclerosis and related vascular diseases. | 19874552 |
| methyldopa, Retinitis, GDC Disease Response Terminology | Altered Intercellular Communication | Activation of the canonical Wnt pathway is sufficient to induce retinal inflammation and oxidative stress and plays a pathogenic role in AMD and DR. | 19875668 |
| Airway structure, Inflammation, Bronchial Hyperreactivity | Altered Intercellular Communication | Reduction of tumstatin in asthmatic airways contributes to angiogenesis, inflammation, and hyperresponsiveness. | 19875687 |
| Carcinoma of lung | Altered Intercellular Communication | This suggests that hormonal influence may not be an important factor to account for the high prevalence of lung cancer among the East-Asian women. | 19875972 |
| Intestinal metaplasia, Inflammation, Atrophic | Altered Intercellular Communication | In per-patient analysis, the accuracy of green mucosa in patients with activity, inflammation, atrophy and intestinal metaplasia was 64, 93, 88 and 81%, respectively. | 19876586 |
| Intestinal metaplasia, Inflammation, Atrophic | Altered Intercellular Communication | In per-biopsy analysis, the accuracy for activity, inflammation, atrophy and intestinal metaplasia was 55, 62, 76 and 76%, respectively. | 19876586 |
| Intestinal metaplasia, Inflammation, Atrophic | Altered Intercellular Communication | Green areas in the gastric body exhibited more inflammation (p < 0.001), atrophy (p < 0.001) and intestinal metaplasia (p < 0.001), whereas purple areas rarely contained atrophy or intestinal metaplasia. | 19876586 |
| Tumor necrosis, Inflammation | Altered Intercellular Communication | Tumor necrosis factor alpha was recently implicated as an important mediator of communication between the peripheral and cerebral immune systems in an animal model of chronic inflammation. | 19877035 |
| Refractory anemias, Inflammation, Rheumatoid Arthritis | Altered Intercellular Communication | The purpose of this study was to examine by proton magnetic resonance spectroscopy ((1)H-MRS) the influence of inflammation on cerebral metabolism in patients with rheumatoid arthritis (RA). | 19877035 |
| Refractory anemias, Inflammation | Altered Intercellular Communication | Our data show that systemic inflammation in RA is associated with metabolic changes in the brain. | 19877035 |
| Degenerative polyarthritis, Inflammation | Altered Intercellular Communication | The goal of this study was to characterize IFP tissue in obese OA patients and to compare its features with thigh subcutaneous AT to determine whether the IFP contributes to local inflammation in knee OA via production of specific cytokines. | 19877065 |
| Degenerative polyarthritis, Inflammation | Altered Intercellular Communication | Our results indicate that the IFP cytokine profile typically found in OA patients could play a role in paracrine inflammation via the local production of IL-6/sIL-6R and that such a profile might contribute to damage in adjacent cartilage. | 19877065 |
| Inflammation | Altered Intercellular Communication | Synovial fluid COMP levels correlated strongly with 2 indicators of knee joint inflammation: early-phase bone scintigraphic findings and synovial fluid volume. | 19877068 |
| Inflammation, Atherosclerosis, Refractory anemias, Coronary Arteriosclerosis, Tumor necrosis | Altered Intercellular Communication | We hypothesized that mediators of inflammation associated with atherosclerosis in other populations (interleukin-6 [IL-6], tumor necrosis factor alpha [TNFalpha], serum amyloid A [SAA], vascular endothelial growth factor, neutrophil count, IL-1alpha, E-selectin, intercellular adhesion molecule 1 [ICAM-1], myeloperoxidase [MPO], matrix metalloproteinase 9, and vascular cell adhesion molecule 1) would be increased and associated with the severity of coronary atherosclerosis in patients with RA. | 19877084 |
| Inflammation, Panuveitis, Visual, Unspecified visual loss | Altered Intercellular Communication | The risk factors for severe visual loss (< or = 0.1) are panuveitis, bilateral inflammation, prolonged visual reduction and a significant number of relapses. | 19877547 |
| Crohn Disease, Osteoporosis | Altered Intercellular Communication | The highest osteoporosis risk was seen in patients with a cumulative 10 - 35 g corticosteroid dose and could be due to both steroid inefficiency in reducing Crohn's disease inflammation as well as the cumulative drug dose and it's adverse effect on patients. | 19877750 |
| Cataract, Inflammation | Altered Intercellular Communication | Evaluation of anterior-segment inflammation and retinal thickness change following cataract surgery. | 19878107 |
| Inflammation, Metabolic Syndrome X, ETV3 wt Allele | Altered Intercellular Communication | Adipose tissue-derived inflammation may contribute to metabolic alterations and eventually to the metabolic syndrome (MetS). | 19878507 |
| Inflammation, ETV3 wt Allele | Altered Intercellular Communication | Non-obese and obese individuals who develop an intense pro-inflammatory state may be more prone to develop the MetS than those with lower levels of inflammation. | 19878507 |
| Inflammation, Pathology | Altered Intercellular Communication | Different patterns in telomere length from PBL are evidenced in rheumatologic pathologies, possibly dependent on the presence or absence of chronic systemic inflammation. | 19879280 |
| Inflammation, Primary malignant neoplasm, Fatigue | Altered Intercellular Communication | Impact of medical Qigong on quality of life, fatigue, mood and inflammation in cancer patients: a randomized controlled trial. | 19880433 |
| Inflammation | Altered Intercellular Communication | It may also produce physical benefits in the long term through reduced inflammation. | 19880433 |
| ARCN1 gene, Inflammation, Chronic Obstructive Airway Disease | Altered Intercellular Communication | The p38 mitogen-activated protein kinase (MAPK) signaling upregulates inflammation and is known to be increased in chronic obstructive pulmonary disease (COPD). | 19880675 |
| ARCN1 gene, Inflammation | Altered Intercellular Communication | SB-681323 is a potent p38 MAPK inhibitor that potentially suppresses inflammation in COPD. | 19880675 |
| Inflammation | Altered Intercellular Communication | The disease manifested as an increase in baseline ANC and reduced maturation time due to increased demand from the inflammation site. | 19880676 |
| Inflammation, Pancreatic Serous Neoplasm | Altered Intercellular Communication | Xanthogranulomatous inflammation of the peripancreatic region mimicking pancreatic cystic neoplasm. | 19881238 |
| Inflammation, Fibrosis Assessment, Parenchyma | Altered Intercellular Communication | Xanthogranulomatous inflammation (XGI) is histopathologically characterized by a marked proliferative fibrosis, parenchymal destruction, and infiltration of foamy histiocytes intermixed with other inflammatory cells. | 19881238 |
| Adenocarcinoma, Inflammation, Benign prostatic hypertrophy | Altered Intercellular Communication | Among others, adenocarcinoma was found in 28.5%, benign prostatic hyperplasia (BPH) alone in 43.3%, BPH with inflammation in 20.3% and inflammation alone in 4.2%. | 19882057 |
| Inflammation, Lung Abscess | Altered Intercellular Communication | Although the lung abscess resolved, the inflammation of the esophagus persisted. | 19882320 |
| Intraocular inflammation | Altered Intercellular Communication | It is associated with significant intraocular inflammation and can lead to poor visual outcome. | 19882507 |
| Narrow Band Imaging, Gastric mucosa, Inflammation | Altered Intercellular Communication | Staining intensity of gastric and duodenal mucosa in the NBI regime was shown to correlate with the degree of inflammation. | 19882880 |
| Rupture, Arterial aneurysm, Hemorrhage | Altered Intercellular Communication | Inflammation of the vessels can result in the development of arterial aneurysms with a potential risk of rupture or bleeding. | 19884215 |
| Inflammation, Lupus Erythematosus | Altered Intercellular Communication | It is possible that the expression of soluble HLA-G in systemic lupus erythematosus is enhanced as part of a mechanism to try to restore the tolerance process towards auto-antigens and to counteract inflammation. | 19884219 |
| Acute heart failure | Altered Intercellular Communication | Serial measurements of neurohormones have been shown to improve prognostication in the setting of acute heart failure (HF) or chronic HF without therapeutic intervention. | 19884490 |
| Inflammation, ALZHEIMER DISEASE 2 | Altered Intercellular Communication | Vascular factors and markers of inflammation in offspring with a parental history of late-onset Alzheimer disease. | 19884614 |
| Inflammation | Altered Intercellular Communication | Amyloid pathology, vascular factors, and inflammation are postulated to be involved in its pathogenesis, but causality has not been established unequivocally. | 19884614 |
| Inflammation | Altered Intercellular Communication | The APOE epsilon4 genotype, vascular factors, production capacity of pro- and anti-inflammatory cytokines upon stimulation with lipopolysaccharide, and circulating markers of inflammation. | 19884614 |
| Inflammation | Altered Intercellular Communication | Black carbon is associated with markers of endothelial function and inflammation. | 19884647 |
| Inflammation, Specimen Type - Fistula | Altered Intercellular Communication | Such a longstanding inflammation of the fistula might have been a possible cause of the development of IMT in this case. | 19885321 |
| Inflammation, Neoplasms | Altered Intercellular Communication | The tumor, which showed signs of inflammation, was located within the bone and the soft tissue. | 19885857 |
| Inflammation | Altered Intercellular Communication | The inflammatory reaction is characterized by increased circulatory levels of various indicators of the severity of inflammation. | 19886071 |
| Inflammation, Cardiovascular Diseases, Cerebrovascular accident | Altered Intercellular Communication | The determination of Lp-PLA2 should be used to predict patient risk of cardiovascular disease and stroke; it does provide additional risk of inflammation when used in conjunction with the traditional markers. | 19886071 |
| Refractory anemias, Rheumatoid Arthritis, Inflammation | Altered Intercellular Communication | Here we studied and characterized different peripheral blood (PB) regulatory T cell (Treg) subsets in rheumatoid arthritis (RA) patients and tested the hypothesis that changes in these cells can be linked to the degree of inflammation and relapsing/remission periods. | 19886735 |
| Refractory anemias, Inflammation | Altered Intercellular Communication | We show that most of these changes parallel the intensity of inflammation, with lowest or highest values in patients with moderately/very active disease compared to healthy controls and at times to patients with inactive RA. | 19886735 |
| Renal Insufficiency, Inflammation, Sepsis | Altered Intercellular Communication | A renal-specific over-expression of beta(2)-AR, resulting from gene delivery, appeared to modulate renal dysfunction and inflammation following sepsis by altering cAMP-PKA, CB-1 and CD14-TLR4-TNF-alpha pathways. | 19887504 |
| Inflammation, Fibrosis Assessment | Altered Intercellular Communication | Noninvasive markers of fibrosis and inflammation in clinical practice: prospective comparison with liver biopsy. | 19887952 |
| Dermatitis | Altered Intercellular Communication | These results show that mast cells express increased levels of PAR-2 in chronic skin inflammation. | 19889021 |
| Inflammatory disease of mucous membrane | Altered Intercellular Communication | Histologic factors for gastric mucosal inflammation were graded according to the guidelines of the Updated Sydney system. | 19889073 |
| Intestinal metaplasia, Gastritis, Infection caused by Helicobacter pylori | Altered Intercellular Communication | Helicobacter pylori infection causes chronic gastric inflammation and intestinal metaplasia (IM), related with deregulation of Wnt pathway and over-expressions of COX-2, matrix metalloproteinase (MMP), and tissue inhibitors of matrix metalloproteinase (TIMP). | 19889076 |
| Inflammation, Epstein-Barr Virus Infections | Altered Intercellular Communication | Chronic inflammation, immune-modifying drugs and Epstein Barr virus infection may be implicated in the pathogenesis of this disease. | 19889478 |
| Inflammation, Immune System Diseases | Altered Intercellular Communication | Immune dysfunction, inflammation, and accelerated aging in patients on antiretroviral therapy. | 19890183 |
| Gastrointestinal Stromal Tumors, Aphthous Stomatitis, Inflammation, Crohn Disease | Altered Intercellular Communication | Pathological examination of the surgical specimen revealed a gastrointestinal stromal tumor as well as aphthous ulcerations and areas of inflammation, which were characteristic of Crohn's disease. | 19891025 |
| Vascular lesions, Inflammation, Pathology | Altered Intercellular Communication | The main pathologies detected on DBE were polyps (14%), vascular lesions (17.6%) and inflammation (12%). | 19891231 |
| Hyperlipidemia, Inflammation | Altered Intercellular Communication | Markedly increased percentage of AA in serum and erythrocyte membrane phospholipid in hyperlipidemic patients receiving gemfibrozil on Step-1 diet is especially important for physiological functions (inflammation, vascular tone, hemostasis etc.) | 19893100 |
| Pain Distress Question, Inflammation | Altered Intercellular Communication | A 30-year-old man presented pain and inflammation in the left epididymis. | 19893140 |
| Inflammation, Neoplasms | Altered Intercellular Communication | Mesothelial origin has been mentioned and inflammation has played some role in the development of these tumors. | 19893140 |
| Inflammation, Sleep Apnea, Obstructive, Hypertension, CTCAE, Osage language | Altered Intercellular Communication | Obstructive sleep apnea (OSA) is related to increased systemic inflammation and arterial hypertension. | 19893310 |
| Inflammation, Gingival Hemorrhage | Altered Intercellular Communication | Slight gingival inflammation was present in 78.5% and gingival bleeding following probing occurred in 53.3%. | 19893958 |
| Inflammation, Necrosis, Mucoepidermoid Carcinoma, Oncocytic metaplasia, Hyperplasia, Squamous metaplasia | Altered Intercellular Communication | The cytopathologic picture showed a quizzical mixture of necrosis and inflammation coupled to hyperplastic changes of the acinar cells, oncocytic metaplasia, and atypical squamous metaplasia of extreme degree simulating high-grade epidermoid- or mucoepidermoid carcinoma. | 19894261 |
| Inflammation, Asthma | Altered Intercellular Communication | Prostaglandin E2 and cysteinyl leukotriene concentrations in sputum: association with asthma severity and eosinophilic inflammation. | 19895589 |
| Asthma | Altered Intercellular Communication | Inflammation of the airways in asthma is associated with the production of cysteinyl leukotrienes (cysLT), prostaglandin (PG)E(2), 8-isoprostane, nitric oxide and other mediators. | 19895589 |
| Inflammation, Asthma | Altered Intercellular Communication | However, the relationship between asthma severity or eosinophilic inflammation and the concentrations of mediators in sputum is unclear. | 19895589 |
| Airway structure, Asthma | Altered Intercellular Communication | To assess sputum PGE(2), cysLT, 8-isoprostane and nitrate concentrations, as well as urinary leukotriene (LT)E(4) and 9alpha,11beta-prostaglandin (PG)F(2) concentrations, in patients with differing severities of asthma and eosinophilic or non-eosinophilic airway inflammation. | 19895589 |
| Airway structure, Asthma | Altered Intercellular Communication | Asthmatic patients were categorized into those with eosinophilic or non-eosinophilic airway inflammation. | 19895589 |
| Airway structure | Altered Intercellular Communication | Sputum PGE(2) concentrations were lower in patients with eosinophilic (1180 pg/mL) compared with non-eosinophilic airway inflammation (2520 pg/mL) (P=0.02). | 19895589 |
| Airway structure | Altered Intercellular Communication | In contrast, sputum cysLT and urinary LTE(4) concentrations were higher in those with eosinophilic airway inflammation (P<0.05). | 19895589 |
| Airway structure | Altered Intercellular Communication | A reduced PGE(2) to cysLT ratio in the airways may adversely affect lung function and contribute to persistence of symptoms and airway remodelling in patients with eosinophilic airway inflammation. | 19895589 |
| ARCN1 gene, Chronic Obstructive Airway Disease, Airway structure | Altered Intercellular Communication | Cigarette smoke is the main cause of chronic obstructive pulmonary disease (COPD), where it can contribute to the observed airway inflammation. | 19897740 |
| Hemorrhage, Hemorrhagic inflammation | Altered Intercellular Communication | Cystoscopy revealed bleeding from the bilateral ureteric orifices without hemorrhagic inflammation of the bladder. | 19897850 |
| Inflammation, Mediastinal Emphysema | Altered Intercellular Communication | Endoscopic muscle exposure during ESD is a significant risk factor for pneumomediastinum, which causes mild inflammation in the early post-ESD phase. | 19899032 |
| Inflammation, Diabetes Mellitus | Altered Intercellular Communication | Chronic low-grade inflammation is related to diabetes risk in population studies. | 19900225 |
| Inflammation, bone destruction | Altered Intercellular Communication | Thus, IL-23 appears to induce joint inflammation and bone destruction by stimulating RANKL expression in RA-FLS. | 19900478 |
| Lagophthalmos, Dryness of eye, Conjunctivitis, Failure (biologic function) | Altered Intercellular Communication | Scores of such risks as infrequent blinking, blink-related microtrauma, conjunctival inflammation, elevated intraocular pressure, dry eye, symblepharon, lagophthalmos, and previous KLAL or penetrating keratoplasty (PKP) failure were calculated and recorded before, during, and after KLAL. | 19901207 |
| Septicemic melioidosis, Sepsis, Inflammation, Infection | Altered Intercellular Communication | The majority of changes observed were common to both septicemic melioidosis and sepsis caused by other infections, including genes related to inflammation, interferon-related genes, neutrophils, cytotoxic cells, and T-cells. | 19903332 |
| Inflammation, Platelet aggregation test result | Altered Intercellular Communication | Inflammation and platelet aggregation and activation are key processes in the initiation of a cardiovascular event. | 19903376 |
| Inflammation, Endothelial dysfunction | Altered Intercellular Communication | Relations of dietary magnesium intake to biomarkers of inflammation and endothelial dysfunction in an ethnically diverse cohort of postmenopausal women. | 19903755 |
| Inflammation, Endothelial dysfunction | Altered Intercellular Communication | Although magnesium may favorably affect metabolic outcomes, few studies have investigated the role of magnesium intake in systemic inflammation and endothelial dysfunction in humans. | 19903755 |
| Inflammation, Endothelial dysfunction | Altered Intercellular Communication | High magnesium intake is associated with lower concentrations of certain markers of systemic inflammation and endothelial dysfunction in postmenopausal women. | 19903755 |
| Inflammation | Altered Intercellular Communication | Microscopically, they were characterized as having normal lipocytes without lipoblasts or inflammation. | 19904221 |
| Inflammation | Altered Intercellular Communication | Chronic inflammation is the hallmark of the pathogenesis of Helicobacter pylori-induced gastric cancer. | 19904747 |
| Inflammation, Primary malignant neoplasm | Altered Intercellular Communication | Interleukin (IL)-17A and IL-17F are inflammatory cytokines expressed by a novel subset of CD4+ Th cells and play critical function in inflammation and probably in cancer. | 19904747 |
| Refractory anemias, Inflammation | Altered Intercellular Communication | Emerging risk factors, markers of inflammation and prothrombotic state such as platelet size are believed to reflect activity of RA. | 19906007 |
| Inflammation, Electrocardiogram: myocardial infarction (finding) | Altered Intercellular Communication | No studies have been addressed to the differences in inflammation kinetics between ST-segment elevation myocardial infarction (STEMI) and non-ST-segment elevation myocardial infarction (NSTEMI). | 19906505 |
| Inflammation, Electrocardiogram: myocardial infarction (finding) | Altered Intercellular Communication | The absence of significant correlations between inflammatory indexes and myocardial infarction in NSTEMI supports the hypothesis that a different pattern of inflammation occurs in these patients. | 19906505 |
| ARCN1 gene, Chronic Obstructive Airway Disease | Altered Intercellular Communication | Chronic obstructive pulmonary disease (COPD) is an inflammatory condition characterized by oxidative stress and the formation of volatile organic compounds (VOCs) secreted via the lungs. | 19906520 |
| Autoimmune Diseases, Inflammatory abnormality of the eye, Complication Aspects, Scleritis | Altered Intercellular Communication | Scleritis is a form of ocular inflammation frequently associated with systemic autoimmune disease and ocular complications. | 19907295 |
| Inflammation | Altered Intercellular Communication | Healing was characterized by a comfortable eye, minimal inflammation, and good cosmetic result. | 19907303 |
| Inflammation, Degenerative disorder | Altered Intercellular Communication | Chronic inflammation is involved in the pathogenesis of chronic age-associated, degenerative diseases. | 19907653 |
| Behcet Syndrome | Altered Intercellular Communication | Behcet's disease is a chronic inflammatory condition involving several organs, such as the skin, mucous membranes, eyes, joints, intestines, lungs and central nervous system. | 19908040 |
| Chronic lymphocytic inflammation, High-Frequency Microsatellite Instability, Neoplasms | Altered Intercellular Communication | BRAF mutation was associated with right-sided tumor location (p < 0.001), higher tumor grade (p = 0.029), absence of peritumoral lymphocytic inflammation (p = 0.026) and MSI-H (p < 0.001). | 19908233 |
| Inflammation | Altered Intercellular Communication | These findings suggest a link between low-grade inflammation and the presence of LVDD. | 19909503 |
| Cataract, Intraocular inflammation, Uveomeningoencephalitic Syndrome | Altered Intercellular Communication | Elevated serum IL-23 correlates with intraocular inflammation after cataract surgery in patients with Vogt-Koyanagi-Harada disease. | 19910285 |
| Cataract, Uveomeningoencephalitic Syndrome, Inflammation | Altered Intercellular Communication | Patients with Vogt-Koyanagi-Harada (VKH) disease are known to have severe inflammation after cataract surgery. | 19910285 |
| Inflammation, Uveomeningoencephalitic Syndrome | Altered Intercellular Communication | This study was designed to investigate the role of IL-17-producing T helper (Th17) cell-related pro-inflammatory cytokines on postoperative inflammation in VKH patients. | 19910285 |
| Uveomeningoencephalitic Syndrome, Uveitis | Altered Intercellular Communication | The data indicate that serum IL-23 levels are significantly elevated in VKH compared with control patients and are strongly associated with postoperative intraocular inflammation. | 19910285 |
| Inflammation, Fibrosis Assessment | Altered Intercellular Communication | IL-13 also up-regulated surface expression of HLA-DR, CD80, CD40, and CD154 by conjunctival fibroblasts, suggesting a potential mechanism for fibroblast-T cell cross talk, via which fibroblasts may actively engage in perpetuating chronic inflammation and continued fibrosis. | 19910508 |
| Inflammation, Acute Coronary Syndrome, GDC AJCC Clinical Stage Terminology | Altered Intercellular Communication | Inflammation plays a key role in the pathogenesis of acute coronary syndromes (ACS). | 19911351 |
| Inflammation, Plaque, Atherosclerotic | Altered Intercellular Communication | Thus, increased expression of 15-LOX-2 in macrophages in hypoxic atherosclerotic plaque may enhance inflammation and the recruitment of inflammatory cells. | 19912316 |
| Airway structure, Chronic Obstructive Airway Disease | Altered Intercellular Communication | Moraxella catarrhalis acquisition, airway inflammation and protease-antiprotease balance in chronic obstructive pulmonary disease. | 19912665 |
| Airway structure | Altered Intercellular Communication | Little is known about the effects of colonization by M. catarrhalis on airway inflammation and protease-antiprotease balance, and how these changes compare to those seen during exacerbations. | 19912665 |
| ARCN1 gene, Colonization, Inflammatory disorder, Airway structure | Altered Intercellular Communication | Since COPD is a progressive inflammatory disease, elucidating the effects of bacterial colonization and exacerbation on airway inflammation is relevant to understanding disease progression in COPD. | 19912665 |
| Airway structure, ARCN1 gene, Colonization | Altered Intercellular Communication | Our aims were (1) Analyze changes in airway inflammation in colonization and exacerbation of COPD due to M. catarrhalis; (2) Explore protease-antiprotease balance in colonization and exacerbation due to M. catarrhalis. | 19912665 |
| ARCN1 gene, Colonization, Exacerbation, Airway structure | Altered Intercellular Communication | Our hypothesis were (1) Acquisition of a new strain of M. catarrhalis in COPD increases airway inflammation from baseline and alters the protease-antiprotease balance towards a more proteolytic environment; (2) These changes are greater during exacerbations associated with M. catarrhalis as compared to colonization. | 19912665 |
| ARCN1 gene, Colonization, Exacerbation, Airway structure | Altered Intercellular Communication | Acquisition of M. catarrhalis in COPD causes increased airway inflammation and worsening protease-antiprotease imbalance during exacerbations and also in colonization, even in the absence of increased symptoms. | 19912665 |
| Airway structure, Arthritis, Helminthiasis | Altered Intercellular Communication | IL-33 has recently been associated with immune responses to helminthic intestinal infections, airway inflammation and arthritis in animal models. | 19913053 |
| Inflammation, Calcinosis | Altered Intercellular Communication | Plaques were scored for the presence of calcification, intimal inflammation, and neovasculature on a 5-point scale. | 19913444 |
| Autoimmune Diseases, Inflammation, Thrombosis | Altered Intercellular Communication | Impact of intimal pathogen burden in acute coronary syndromes--correlation with inflammation, thrombosis, and autoimmunity. | 19914090 |
| Inflammation, "Alzheimers Disease", Data types - Address | Altered Intercellular Communication | A large body of evidence suggests the importance of inflammation and oxidative or nitrosative stress in Alzheimer's disease (AD) pathogenesis. | 19914323 |
| Inflammation, Rheumatoid Arthritis | Altered Intercellular Communication | Vaspin and omentin: new adipokines differentially regulated at the site of inflammation in rheumatoid arthritis. | 19914904 |
| Inflammation, Aneurysm, Mycotic | Altered Intercellular Communication | Although mycotic aneurysm with inflammation tissue usually interferes with surgical manipulation because of severe adhesion to the lung, semi-clamshell approach helped us perform all these procedures. | 19914927 |
| Inflammation, Atherosclerosis | Altered Intercellular Communication | Estrogen induces nitric oxide (NO) in the endothelium and appears to protect against inflammation and atherosclerosis. | 19914929 |
| Inflammation, Anemia, Vascular calcification | Altered Intercellular Communication | Higher free p-cresylsulphate levels (>0.051 mg/100 mL; median) were associated with mortality independently of well-known predictors of survival such as age, vascular calcification, anaemia and inflammation. | 19914995 |
| Inflammation, Kidney damage | Altered Intercellular Communication | C-reactive protein (CRP), a marker for inflammation, has been recently associated with early kidney damage. | 19914996 |
| Inflammation, Kidney damage | Altered Intercellular Communication | This suggests that inflammation may play a role in early kidney damage. | 19914996 |
| Inflammation, Discitis | Altered Intercellular Communication | Fungal spondylodiskitis (inflammation of intervertebral disk tissue and adjacent vertebrae) is rare, particularly in immunocompetent patients. | 19915311 |
| Inflammation | Altered Intercellular Communication | Serum TRAP 5a, on the other hand, has no relationship to bone metabolism but seems instead to be a measure of activated macrophages and chronic inflammation. | 19915788 |
| Airway structure, Asthma | Altered Intercellular Communication | Oncostatin M may link airway inflammation to remodeling in asthma. | 19916861 |
| Sample Size Calculation, Inflammation | Altered Intercellular Communication | These results suggest that anti-ATF-2 Ab is a new autoantibody in SSc and that it serves as a novel serological marker for inflammation and lung involvement in SSc. | 19917156 |
| Juvenile arthritis, Inflammation | Altered Intercellular Communication | Exposure to stagnant polluted air may be an environmental risk factor for JIA in young children, potentially triggered by pollution-induced pulmonary mediated inflammation. | 19917177 |
| Inflammation, Malnutrition, Endothelial dysfunction, Atherosclerosis | Altered Intercellular Communication | Endothelial dysfunction (ED) is a common, early abnormality that predisposes patients to develop atherosclerosis and cardiovascular events; inflammation is associated with atherosclerosis and malnutrition. | 19917360 |
| Inflammation, Crypt abscess, Stenosis, Ulcer, Lobular Endocervical Glandular Hyperplasia, Crohn Disease | Altered Intercellular Communication | Subsequent laparoscopy led to the identification of severe, active Crohn disease with strictures, ulcers, crypt abscesses, pyloric metaplasia, and transmural inflammation. | 19917475 |
| Inflammation, Heart failure | Altered Intercellular Communication | We examined whether the antiinflammatory action of statins may be of benefit in heart failure, a state characterized by inflammation in which low cholesterol is associated with worse outcomes. | 19917888 |
| Inflammation | Altered Intercellular Communication | A punch biopsy showed granulomatous inflammation and associated PXE-like changes. | 19917959 |
| Pain Distress Question, Fatigue | Altered Intercellular Communication | Factor analysis identified Disease Activity Score-28 (DAS28) and swollen (SJC) and tender joint count (TJC) as a physician-inflammation factor, and patient global assessment, pain, Health Assessment Questionnaire, and fatigue as patient components. | 19918042 |
| Refractory anemias, Inflammation | Altered Intercellular Communication | IL-33 was produced mainly in inflamed joints; IL-33/ST2L signaling might play an important role in joint inflammation of human RA. | 19918048 |
| Inflammation, Neoplasms, Diverticular Diseases | Altered Intercellular Communication | Bowel preparation, polyps, angioectasias, diverticular disease, inflammation and neoplasm were also verified. | 19918681 |
| Communicable Diseases, Fibrosis Assessment, Hepatic inflammation, Hepatitis C | Altered Intercellular Communication | Association among Fas expression in leucocytes, serum Fas and Fas-ligand concentrations and hepatic inflammation and fibrosis in chronic hepatitis C. Replication of the hepatitis C virus (HCV) in peripheral blood mononuclear cells (PBMC) may impair immune functions and establish persistent infection. | 19919570 |
| Fibrosis Assessment, Hepatitis | Altered Intercellular Communication | Fas expression on monocytes was lower in advanced stages of liver inflammation and fibrosis. | 19919570 |
| Inflammation, Ischemic stroke | Altered Intercellular Communication | Polymorphisms of G-572C and G-174C in the interleukin-6 (IL-6) promoter can affect both the transcription and secretion of IL-6 and may be involved in inflammation related to and the pathogenesis of ischemic stroke (IS). | 19919828 |
| Inflammation, Heart failure | Altered Intercellular Communication | Inflammation has been implicated in the pathogenesis of heart failure (HF), but knowledge about the production and role of inflammatory actors remains incomplete. | 19919988 |
| vascular inflammations | Altered Intercellular Communication | On the basis of its role in vascular inflammation, vascular proliferation, and matrix degradation, we hypothesized a role for the chemokine CXCL16 in the pathogenesis of myocardial remodeling and development of HF. | 19919988 |
| vascular inflammations, Dissection of aorta | Altered Intercellular Communication | An adventitial IL-6/MCP1 amplification loop accelerates macrophage-mediated vascular inflammation leading to aortic dissection in mice. | 19920349 |
| vascular inflammations, Aortic Aneurysm, Cardiovascular Diseases | Altered Intercellular Communication | Vascular inflammation contributes to cardiovascular diseases such as aortic aneurysm and dissection. | 19920349 |
| vascular inflammations | Altered Intercellular Communication | We have shown here that subcutaneous infusion of Ang II, a vasopressor known to promote vascular inflammation, into older C57BL/6J mice induced aortic production of the proinflammatory cytokine IL-6 and the monocyte chemoattractant MCP-1. | 19920349 |
| vascular inflammations | Altered Intercellular Communication | These results suggest that leukocyte-fibroblast interactions in the aortic adventitia potentiate IL-6 production, inducing local monocyte recruitment and activation, thereby promoting MCP-1 secretion, vascular inflammation, ECM remodeling, and aortic destabilization. | 19920349 |
| Degenerative polyarthritis, Inflammation | Altered Intercellular Communication | Osteoarthritis (OA) is characterized by progressive cartilage degradation and secondary inflammation of the synovial membrane. | 19922256 |
| Inflammation, Thrombosis, ENL Protein, Arteritis, Erythema, Type 2 lepra reaction | Altered Intercellular Communication | Eight weeks after stopping her medications, she developed a severe and recalcitrant erythema (nodosum) leprosum (ENL) which presented histologically with thrombosed small veins and neutrophilic inflammation in fat septa, but without arteritis. | 19922466 |
| Inflammation, Heart failure | Altered Intercellular Communication | Although increasing evidence supports immune-mediated inflammation plays an important role in the pathophysiology of heart failure, little is known regarding the source and mechanism that trigger immune responses. | 19923020 |
| Gastroesophageal reflux disease, Chronic Obstructive Airway Disease, Chronic pain, Heart failure, Depression, CTCAE | Altered Intercellular Communication | 46% had gastro-oesophageal reflux disease, 25% depression, 20% chronic airways disease or chronic pain and 15% also had heart failure or inflammation-pain. | 19923032 |
| Nephritis | Altered Intercellular Communication | Bradykinin and high glucose promote renal tubular inflammation. | 19923143 |
| Inflammation, Fever, CTCAE | Altered Intercellular Communication | After allogeneic stem cell transplantation, a 49-year-old man developed fever and inflammation at the site of a plant puncture on a finger. | 19923491 |
| Inflammation, Corneal Endothelial Cell Loss | Altered Intercellular Communication | High-volume priming of the CPB circuit with a modern balanced HES solution resulted in reduced inflammation, less endothelial damage, and fewer alterations in renal tubular integrity compared with an albumin-based priming. | 19923501 |
| Inflammation, Sleep Apnea, Obstructive, Osage language | Altered Intercellular Communication | The relationship between obstructive sleep apnea (OSA) and atherosclerosis-related inflammation has been poorly investigated, particularly focusing on functional responses of immune cells playing a key role in atherogenesis and in comparison with control groups with similar cardiovascular risk factors which are known to be themselves associated with inflammation. | 19924457 |
| Inflammation | Altered Intercellular Communication | Studies designed to investigate OSA-associated inflammation should carefully match the control group subjects. | 19924457 |
| Carcinogenesis, Malignant neoplasm of endometrium | Altered Intercellular Communication | In conclusion, our findings confirmed a reduction in risk of endometrial cancer with factors associated with a lower cumulative exposure to estrogen and/or higher exposure to progesterone, such as increasing number of FTPs and shorter menstrual lifespan and, therefore, support an important role of hormonal mechanisms in endometrial carcinogenesis. | 19924816 |
| Inflammation, Lymphoid | Altered Intercellular Communication | Nevertheless, infection of lymphoid cells, sustained by a low level of replication, could be sufficient to increase the local injury through an autologous mechanism of inflammation. | 19926147 |
| Autoimmune Diseases, Inflammation | Altered Intercellular Communication | We evaluated the influence of inflammation on cardiac endocrine function in autoimmune rheumatic disease (RD) patients with preserved left ventricular systolic function. | 19926149 |
| Inflammation, atherosclerotic | Altered Intercellular Communication | Four atherosclerotic stages were defined by signs of degeneration and inflammation in sections stained with Elastica-van-Gieson and immunohistology, respectively. | 19926495 |
| Inflammation, Atherosclerosis | Altered Intercellular Communication | Less severe atherosclerosis in the IMA than in the SMA was associated with stronger signs of inflammation. | 19926495 |
| Sleep-Disordered Breathing, No metabolic abnormalities, daytime sleepiness, Inflammation | Altered Intercellular Communication | Sleep-disordered breathing in obese children is associated with prevalent excessive daytime sleepiness, inflammation, and metabolic abnormalities. | 19926716 |
| vascular inflammations, Dental Plaque | Altered Intercellular Communication | Our data suggest that neurotransmitters such as substance P are capable of promoting mast cell dependent plaque destabilization and provide a new, direct link between neural factors and vascular inflammation. | 19926877 |
| vascular inflammations, Dental Plaque | Altered Intercellular Communication | Our data suggest that neurotransmitters such as substance P are capable of promoting mast cell dependent plaque destabilization and provide a new, direct link between neural factors and vascular inflammation. | 19926877 |
| Inflammation | Altered Intercellular Communication | Patients from group III had more prominent inflammation, but only 35% of them were H. pylori (+). | 19927999 |
| Inflammation | Altered Intercellular Communication | Cellular proliferation had positive correlation with inflammation grade in groups II and III (P <0,05). | 19927999 |
| Primary hypogonadism | Altered Intercellular Communication | The hormonal tests were performed that allowed to diagnose the hypergonadotropic hypogonadism. | 19928664 |
| Inflammation, Fibrosis Assessment | Altered Intercellular Communication | Both multifocal fibrosclerosis and hypertrophic pachymeningitis are rare disorders of unknown etiology, characterised by chronic inflammation leading to dense fibrosis. | 19928692 |
| Inflammation, Hemorrhage, Azotemia, Graft-vs-Host Disease | Altered Intercellular Communication | Instead, bleeding risk was determined by platelet count, presence of inflammation, azotemia, presence of graft-versus-host disease and treatment with low-molecular weight heparin. | 19929239 |
| Inflammation | Altered Intercellular Communication | The increase in visfatin may contribute to low-grade systemic inflammation associated with MetS. | 19929281 |
| Orbital Pseudotumor | Altered Intercellular Communication | Triamcinolone acetonide injection for persistent atypical idiopathic orbital inflammation. | 19929669 |
| Orbital Pseudotumor | Altered Intercellular Communication | To report a patient with atypical idiopathic orbital inflammation who was successfully treated with intra-orbital injections of triamcinolone acetonide. | 19929669 |
| Conjunctivitis, Orbital Pseudotumor, Right eye | Altered Intercellular Communication | A 71-year-old female with right orbital mass and conjunctival inflammation underwent orbital biopsy that was consistent with the diagnosis of atypical idiopathic orbital inflammation. | 19929669 |
| Orbital Pseudotumor | Altered Intercellular Communication | Intra-orbital injections of triamcinolone acetonide may be an effective alternative in patients with atypical idiopathic orbital inflammation unresponsive to systemic steroids. | 19929669 |
| Inflammation, "Cyst of Skenes duct", Congenital Abnormality | Altered Intercellular Communication | In the adult female, a cyst of the Skene's duct is a rare event that may be either the late consequence of a congenital abnormality or the result of a chronic acquired inflammation. | 19929913 |
| Inflammation | Altered Intercellular Communication | Patients with NAEC were characterized by mild eosinophilic inflammation and only minor structural conjunctival changes. | 19930216 |
| Inflammation, Carcinogenesis | Altered Intercellular Communication | The transcription factor Nuclear factor kappa B (NF-kappaB) is central to the regulation of genes encoding for mediators of inflammation and carcinogenesis. | 19930402 |
| Barrett Esophagus, Inflammation, Adenocarcinoma | Altered Intercellular Communication | In the esophagus, NF-kappaB is progressively activated from inflammation to Barrett's metaplasia and adenocarcinoma. | 19930402 |
| Inflammation | Altered Intercellular Communication | The diagnoses of GU in 21(66%), DU in 16(50%), GC in 20(50%) and NUD in 50(42%) were associated with moderately active chronic inflammation. | 19930551 |
| Inflammation | Altered Intercellular Communication | CagA in 55(45%) (p = 0.037), vacA s1am1 in 51(51%) (P < 0.001), s1bm1 in 25(56%) (p = 0.002), s1am2 32(30%) (p < 0.001) and s1bm2 29(69%) (p = 0.004) were also associated with moderately active chronic inflammation. | 19930551 |
| Inflammation, Disease | Altered Intercellular Communication | VacA allele's s1am1 and s1bm1 were associated with H. pylori associated diseases and inflammation. | 19930551 |
| Inflammation | Altered Intercellular Communication | Chronic low-grade inflammation is a characteristic of ageing that may lead to alterations in health status and quality of life. | 19930773 |
| Airway structure, Granulomatosis with polyangiitis, Subglottic stenosis, Disease remission | Altered Intercellular Communication | In patients with Wegener's granulomatosis, subglottic stenosis can develop due to active disease; however, some patients develop subglottic stenosis with no clear evidence of airway inflammation. | 19930784 |
| Inflammation, Sleep Apnea, Obstructive, Blood coagulation, GDC AJCC Clinical Stage Terminology | Altered Intercellular Communication | This study indicates that OSAS is associated with inflammation and increased IVST in ACS patients after successful PCI and, in elderly ACS patients, also with CAD severity and enhanced blood coagulability. | 19930839 |
| Inflammation | Altered Intercellular Communication | Plaque instability might be caused, however, by pathophysiologic processes, such as inflammation ("panarteritis"), that exert adverse effects throughout the coronary vasculature and therefore result in multiple unstable lesions and multivessel thromboses. | 19931792 |
| Inflammation, Intervertebral Disc Degeneration, Pain Distress Question | Altered Intercellular Communication | Once degenerative disc disease has begun, the tissue inflammation that accompanies DDD may further increase vitamin C requirements in the affected patient, thereby creating a cascade of positive feedbacks that potentially accelerates and contributes to further disc degeneration and low-back pain. | 19932568 |
| methyldopa, Inflammation, Cataract | Altered Intercellular Communication | These data suggest only a weak link between systemic inflammation and AMD and cataract in Asian people. | 19933187 |
| Inflammation, Degenerative disorder | Altered Intercellular Communication | Early-stage findings consisted of inflammatory changes involving adjacent vertebral endplates and mimicking degenerative disk disease with inflammation. | 19933625 |
| Inflammation, Synovitis | Altered Intercellular Communication | A synovitis grading system was used to determine the severity of synovial inflammation. | 19933745 |
| Inflammation, Morbidity - disease rate | Altered Intercellular Communication | This chronic inflammation, or ''inflammaging'' as it has been termed, seems to be associated with a host of adverse effects contributing to many of the health problems that increase morbidity and decrease both quality of life and the ability to maintain independence in old age. | 19934111 |
| Inflammation, Chronic disease, Atherosclerosis | Altered Intercellular Communication | At the same time, inflammation arising from atherosclerosis and other chronic diseases further contributes to the inflammatory milieu and effects a state of chronic inflammation. | 19934111 |
| Inflammation, Morbidity - disease rate | Altered Intercellular Communication | This chronic inflammation, or ''inflammaging'' as it has been termed, seems to be associated with a host of adverse effects contributing to many of the health problems that increase morbidity and decrease both quality of life and the ability to maintain independence in old age. | 19934111 |
| Granulomatous inflammation, Sarcoidosis | Altered Intercellular Communication | Subsequent biopsies showed granulomatous inflammation consistent with sarcoidosis. | 19934463 |
| Retinal Perforations, Intraocular inflammation, Endophthalmitis, CTCAE, Retinal Detachment | Altered Intercellular Communication | The charts were reviewed to identify the complications of endophthalmitis, intraocular inflammation, retinal tear, and retinal detachment. | 19934815 |
| Endophthalmitis, CTCAE, Uveitis | Altered Intercellular Communication | Two cases of unilateral culture-proven endophthalmitis occurred after bilateral intravitreal ranibizumab, and one case of unilateral acute intraocular inflammation occurred after bilateral intravitreal bevacizumab. | 19934815 |
| Endophthalmitis, CTCAE, Uveitis | Altered Intercellular Communication | The incidence of culture-proven endophthalmitis was 0.065%, and the incidence of acute intraocular inflammation was 0.033%. | 19934815 |
| Uveitis | Altered Intercellular Communication | Severe acute intraocular inflammation can occur unilaterally after same-day bilateral injections of bevacizumab. | 19934815 |
| Inflammation, Metabolic Syndrome X, Coronary heart disease | Altered Intercellular Communication | The influence of cardiac rehabilitation on inflammation and metabolic syndrome in women with coronary heart disease. | 19935427 |
| Inflammation, Hepatitis C | Altered Intercellular Communication | These findings raise the possibility that in some cases hepatitis C infection and inflammation can be directly oncogeneic. | 19935643 |
| Inflammation, Esophagitis | Altered Intercellular Communication | Esophageal dilation in eosinophilic esophagitis: effectiveness, safety, and impact on the underlying inflammation. | 19935783 |
| Esophagitis | Altered Intercellular Communication | In addition, we examined the influence of dilation on the underlying esophageal inflammation. | 19935783 |
| Inflammation | Altered Intercellular Communication | Symptom improvement despite persistence of inflammation suggests that tissue remodeling contributes substantially to symptom generation in EoE. | 19935783 |
| Dystrophy, Inflammation, Cerebral Amyloid Angiopathy | Altered Intercellular Communication | They develop robust AD-like cerebral beta-amyloid plaque pathology with glial inflammation, signs of neuritic dystrophy and cerebral amyloid angiopathy. | 19936202 |
| Inflammation, Idiopathic Pulmonary Fibrosis, Liver diseases, Autoimmune Diseases, Fibrosis Assessment, Macrocytosis, Leukemia, Myelocytic, Acute | Altered Intercellular Communication | In six generations of a large family, a loss-of-function mutation in the telomerase enzyme gene TERT associated with severe telomere shortening and a range of hematologic manifestations, from macrocytosis to acute myeloid leukemia, with severe liver diseases marked by fibrosis and inflammation, and one case of idiopathic pulmonary fibrosis but not with autoimmune disorders. | 19936245 |
| Inflammation, Fibrosis Assessment, Epithelial | Altered Intercellular Communication | Our analyses showed that 60% of HCV positive samples showed nasal epithelial erosion, 95% showed subepithelial non-specific inflammation and/or fibrosis, while only 5% showed normal histology. | 19936373 |
| Prostate carcinoma, Benign prostatic hypertrophy, prostatitis | Altered Intercellular Communication | To study the association and possible relationship of prostate inflammation with benign prostatic hyperplasia (BPH), and prostate cancer. | 19936421 |
| Inflammation, Acute inflammation | Altered Intercellular Communication | Of them, only one demonstrated acute inflammation, while 87/88 demonstrated chronic inflammation with, or without acute inflammation. | 19936421 |
| Inflammation, Primary malignant neoplasm | Altered Intercellular Communication | Histopathologic features were categorized into 3 main categories: inflammation alone (12/214, 5.6%), BPH category (126/214, 58.9%), and cancer category (76/214, 35.5%) patients. | 19936421 |
| Inflammation, Primary malignant neoplasm | Altered Intercellular Communication | In the overall analysis of 214 specimens, BPH with inflammation was more prevalent than cancer with inflammation (43/214 [20.1%] versus 33/214 [15.4%]). | 19936421 |
| Inflammation, Primary malignant neoplasm | Altered Intercellular Communication | In a subgroup analysis within each category, inflammation was less prevalent in the BPH category compared to the cancer category (43/126 [34.1%] versus 33/76 [43.4%]). | 19936421 |
| Inflammation, Primary malignant neoplasm | Altered Intercellular Communication | The association between chronic inflammation and both BPH and cancer is obvious in our study. | 19936421 |
| Inflammation, Primary malignant neoplasm | Altered Intercellular Communication | Further studies are needed to substantiate this observation, and to clarify the magnitude of association of inflammation with BPH compared to cancer. | 19936421 |
| vascular inflammations, Metabolic Syndrome X | Altered Intercellular Communication | Evaluation of the degree of vascular inflammation in patients with metabolic syndrome. | 19936455 |
| Inflammatory Bowel Diseases, Inflammation | Altered Intercellular Communication | Inflammation in IBD may be caused by the loss of homeostasis between CD4+ CD25high Foxp3+ regulatory cells (Treg) and proinflammatory Th17 cells. | 19936899 |
| PMF Regimen, Granulomatous inflammation, Carcinoma of lung | Altered Intercellular Communication | Therefore, it might have a limited role in the diagnosis of PMF with possible concurrent granulomatous inflammation or lung cancer. | 19937406 |
| Inflammation, Ulcer | Altered Intercellular Communication | Colonoscopy was normal in 11 (45.8%), showed inflammation or superficial ulcers in 7 (29.1%) and solitary or multiple deep ulcers in 6 (25%). | 19937416 |
| Neurogenic Inflammation, Data types - Address, physiopathological | Altered Intercellular Communication | Of the 5485 genes found to be significantly altered in AD, there were consistent patterns of changes which show that the AD transcriptome in neocortex is characterized by changes indicative of synaptic dysfunction, perturbed neurotransmission and activation of neuroinflammation. | 19937809 |
| Inflammation, N-nitrosomorpholine, Neuromyelitis Optica | Altered Intercellular Communication | Severe inflammation and astrocyte loss with profound demyelination in spinal cord and optic nerves are typical pathological features of neuromyelitis optica (NMO). | 19937948 |
| Inflammation, N-nitrosomorpholine | Altered Intercellular Communication | Human anti-AQP-4 antibodies are not only important in the diagnosis of NMO but also augment disease and induce NMO-like lesions in animals with T-cell-mediated brain inflammation. | 19937948 |
| Hormone abnormality | Altered Intercellular Communication | Many conditions including hormonal abnormality are associated with this syndrome. | 19938750 |
| Hyponatremia | Altered Intercellular Communication | Hormonal changes will cause fluctuation in hyponatremia and correction of hyponatremia, even if the recommended rate may be hazardous and will promote ODS. | 19938750 |
| Inflammation | Altered Intercellular Communication | Microscopic examination of the biopsy specimens suggested only chronic inflammation. | 19938751 |
| Retinal Pigments, Inflammatory abnormality of the eye | Altered Intercellular Communication | There was no evidence of ocular inflammation or related retinal or retinal pigment epithelial changes. | 19939456 |
| Inflammation, Cardiovascular Diseases, Cyclophosphamide/Vincristine/Dacarbazine Regimen, Degenerative polyarthritis, Obesity, No metabolic abnormalities | Altered Intercellular Communication | Osteoarthritis (OA) and cardiovascular disease (CVD) share age and obesity as risk factors, but may also be linked by pathogenic mechanisms involving metabolic abnormalities and systemic inflammation. | 19940413 |
| Chronic inflammation, Neoplasms | Altered Intercellular Communication | At virtual and conventional cystoscopies, the conditions of 3 patients, 2 with chronic inflammations and 1 with foreign body reaction, were wrongly diagnosed as tumors. | 19940652 |
| Inflammation, Fever, CTCAE, Mumps, Deafness, Virus Diseases, Orchitis | Altered Intercellular Communication | Mumps is a vaccine-preventable viral infection characterized by fever and inflammation of the salivary glands and whose complications include orchitis, deafness, and meningo-encephalitis. | 19940833 |
| Inflammation, Obesity | Altered Intercellular Communication | However, obesity is associated with disability and with physiological markers also recently linked with frailty, for example, increased inflammation and low antioxidant capacity. | 19942592 |
| Inflammation, Atrial Fibrillation by ECG Finding | Altered Intercellular Communication | Although inflammation has been shown to be implicated in the pathophysiology of atrial fibrillation (AF), little is known about its involvement in the accompanying atrial electrical remodeling expressed by P wave dispersion (P(disp)). | 19942863 |
| Inflammation, Hypertensive (finding) | Altered Intercellular Communication | In hypertensive subjects hs-CRP and P(disp) are interrelated and associated with AF, suggesting an active implication of inflammation in the atrial electrophysiological remodeling predisposing to AF. | 19942863 |
| Infertility | Altered Intercellular Communication | Studies of the anatomy and the physiology of the uterine-tubal junction (UTJ), with a main concern for the muscular pattern and the secretory activity of this part of the tube, in relation with the hormonal and nervous control, can play an important role in understanding and impairment of infertility. | 19942965 |
| Perforation (observation) | Altered Intercellular Communication | The histopathologic report revealed granulomatous giant-cellular inflammation in the margins of the perforation. | 19942978 |
| Inflammation, Perforation of ileum | Altered Intercellular Communication | The granulomatous giant-cellular inflammation of foreign body is a rare cause of ileal perforation. | 19942978 |
| Inflammation, Chronic heart failure, Congestive heart failure | Altered Intercellular Communication | The cytokine hypothesis suggests that there is an association between chronic heart failure (CHF) and inflammation. | 19944358 |
| Inflammation | Altered Intercellular Communication | In a subgroup of 15 subjects, reduced post-exercise HRR was associated with increased serum markers of inflammation (interleukin-6, r = 0.58, P = .024; high-sensitivity C-reactive protein, r = 0.66, P = .007). | 19944361 |
| Inflammation | Altered Intercellular Communication | Pathophysiologic links between autonomic function and inflammation may be mediators of this association. | 19944361 |
| Inflammation, "Alzheimers Disease", Postoperative cognitive dysfunction | Altered Intercellular Communication | Inflammation: a bridge between postoperative cognitive dysfunction and Alzheimer's disease. | 19944539 |
| Refractory anemias, Inflammation | Altered Intercellular Communication | Simultaneously, RA activity was assessed using inflammation markers, MMP-3 and the Disease Activity Score in 28 joints (DAS-28) based on CRP [DAS-28(CRP)] and ESR[DAS-28(ESR)]. | 19944558 |
| daytime sleepiness | Altered Intercellular Communication | Increased daytime sleepiness in this middle aged series was related to female (hormonal status and sedentarism) and partner factors; several which are susceptible of intervention. | 19945237 |
| vascular inflammations | Altered Intercellular Communication | PTX3 may be a useful marker for localized vascular inflammation and damage to the cardiovascular system. | 19945702 |
| Inflammation, Dyslipidemias, Obesity, Cardiovascular Diseases | Altered Intercellular Communication | Obesity, dyslipidemia, and inflammation were prominent among HIV-infected adolescent women and, coupled with other risk factors, may accelerate the lifetime risk of cardiovascular disease and other adverse events. | 19947855 |
| Airway structure | Altered Intercellular Communication | Analysis of exhaled breath condensate (EBC) pH is a non-invasive method to study airway inflammation. | 19947991 |
| Lymphocyte count increased, Inflammation | Altered Intercellular Communication | Increased C-reactive protein with lymphocytosis suggested inflammation as its cause. | 19950763 |
| Bronchitis | Altered Intercellular Communication | Orally administered inactivated nontypeable Haemophilus influenzae (NTHi) can drive a specific T-cell response that by promoting intrabronchial phagocytosis down-regulates bronchus inflammation. | 19952063 |
| Inflammation, Hypertensive (finding) | Altered Intercellular Communication | Relationship between renal resistive index and inflammation in untreated hypertensive patients. | 19952472 |
| Inflammation, Hypertensive (finding), Albuminuria | Altered Intercellular Communication | Renal resistive index is associated with inflammation and may be a useful marker, together with albuminuria, in hypertensive patients when evaluating hypertensive renal damage. | 19952472 |
| Inflammation, Parakeratosis, Acantholysis, Hyperkeratosis | Altered Intercellular Communication | For each case, the following histologic features were evaluated and their association with disease course was examined: pseudo-invasion, adnexal involvement, signet-ring cells, cytologic atypia, glands formation, epidermal acantholysis, parakeratosis, hyperkeratosis, and chronic inflammation. | 19952933 |
| Inflammatory abnormality of the eye | Altered Intercellular Communication | Of the 19 eyes, 14 showed moderate to severe ocular inflammation immediately after injection. | 19952993 |
| Inflammation, Vitreous opacities | Altered Intercellular Communication | Five eyes with severe inflammation underwent pars plana vitrectomy because of dense vitreous opacity. | 19952993 |
| ovarian neoplasm | Altered Intercellular Communication | Physical activity may influence ovarian cancer risk through hormonal, inflammatory, or immune-mediated processes or by suppressing ovulation. | 19953315 |
| Nasal inflammation | Altered Intercellular Communication | Even numbered 3-OHFA were most strongly associated with nasal inflammation. | 19953416 |
| Airway structure | Altered Intercellular Communication | This is the first study to evaluate the relationship between endotoxin's 3-OHFA constituents in agricultural dust and nasal airway inflammation. | 19953416 |
| Inflammation, Fatty degeneration | Altered Intercellular Communication | Steatosis was infrequent and focal or even absent, whereas variable grades of Mallory hyaline and inflammation were consistently present. | 19954815 |
| Inflammatory Bowel Diseases | Altered Intercellular Communication | TRAIL was downregulated in enterocytes of patients with IBD, but was upregulated in mononuclear cells in areas of active mucosal inflammation. | 19954896 |
| Inflammatory disease of mucous membrane | Altered Intercellular Communication | TRAIL-R2 and TRAIL-R4 were strongly downregulated in the surface epithelium in any kind of mucosal inflammation. | 19954896 |
| ARCN1 gene, Inflammation, Chronic Obstructive Airway Disease | Altered Intercellular Communication | We hypothesized that systemic inflammation in patients with chronic obstructive pulmonary disease (COPD) may influence Epo production, particularly during episodes of exacerbation of the disease (ECOPD) where an inflammatory burst is known to occur. | 19955699 |
| Inflammation, Chronic Obstructive Airway Disease | Altered Intercellular Communication | These results show that the plasma levels of Epo are reduced during ECOPD likely in relation to a burst of systemic inflammation. | 19955699 |
| Inflammation, Observation Method - Coagulation, Endothelial dysfunction | Altered Intercellular Communication | Morning fasting blood samples were collected to determine measures of inflammation, coagulation and endothelial dysfunction. | 19955705 |
| Inflammation, Impaired health, Endothelial dysfunction | Altered Intercellular Communication | Perceived impairment in sleep related to increased coagulation activity and endothelial dysfunction in all participants, whereas objectively impaired sleep related to inflammation activity in caregivers. | 19955705 |
| Inflammation | Altered Intercellular Communication | Exercise training as a treatment for chronic inflammation in the elderly. | 19955865 |
| Disability, Inflammation, Chronic disease, Sarcopenia | Altered Intercellular Communication | Persistent subclinical inflammation predisposes to chronic disease, as well as the development of sarcopenia and disability, in frail elderly. | 19955865 |
| Inflammation | Altered Intercellular Communication | This article highlights emerging data suggesting that increasing physical activity could be effective for reducing chronic inflammation in the elderly. | 19955865 |
| Inflammation, Neoplasm Metastasis | Altered Intercellular Communication | Traditionally, heparanase activity was implicated in cellular invasion associated with angiogenesis, inflammation, and cancer metastasis. | 19955948 |
| Coronary Occlusion, Neoplasms | Altered Intercellular Communication | Urgent coronary angiography excluded an acute coronary occlusion, whereas high-resolution computed tomography of the chest revealed tumor infiltration and associated acute inflammation of the pericardial sac. | 19956075 |
| Autoimmune Diseases | Altered Intercellular Communication | Predominance of women in autoimmune diseases suggests that sex hormones may play a role in disease susceptibility. | 19957009 |
| Inflammation, "Alzheimers Disease", Data types - Address | Altered Intercellular Communication | Inflammation is a key component of Alzheimer's disease (AD), and we have examined the effect of two polymorphisms (-174G/C and -572C/G) in the promoter of the inflammatory cytokine interleukin-6 (IL-6) gene on risk of AD in 318 AD patients. | 19957198 |
| Inflammation, Hyperemia | Altered Intercellular Communication | In such cases PV was macroscopically not changed or had various grades of change--from hyperemia, cicatricial thickening and involvement into adhesive process to its pronounced inflammation and destruction. | 19957726 |
| Inflammation, Pleurisy | Altered Intercellular Communication | The reported complications after video-assisted thoracoscopical operations--4 purulent inflammation of thoracoportal incisions, 3--marginal pleuritis. | 19957756 |
| Inflammation, Primary, Ulcerative Colitis | Altered Intercellular Communication | If apoptosis is a primary defect, apoptosis rates could influence the degree of spreading of inflammation and the clinical course of UC. | 19958058 |
| Inflammation | Altered Intercellular Communication | However, increased microscopic inflammation inversely correlated with apoptosis response to the Fas ligand (p< 0.06). | 19958058 |
| Airway structure, IL13 gene | Altered Intercellular Communication | Allergic rhinitis (AR) is characterized in part by hyperresponsiveness to nonspecific stimuli, a phenomenon that reflects the fundamental role of nasal neural pathways in chronic airway inflammation. | 19958603 |
| Inflammation | Altered Intercellular Communication | Alterations in neurogenic inflammation may contribute to the pathophysiology of CRS and provide alternative therapeutic targets. | 19958603 |
| Cessation of life, Necrosis with inflammation | Altered Intercellular Communication | Previous studies have shown that declines in human fibroblast ATP levels interfere with programmed cell death and promote necrotic inflammation. | 19958786 |
| Inflammation | Altered Intercellular Communication | We discuss the differential diagnoses and various diagnostic tests with respect to granulomatous inflammation of the meninges. | 19960146 |
| Inflammation, Fibrosis Assessment | Altered Intercellular Communication | Pulmonary fibrosis represents the final evolution of a chronic inflammation and is defined by the overgrowth of fibroblasts and exaggerated extracellular matrix deposition. | 19960789 |
| Inflammation, Granulomatous inflammation, Granuloma | Altered Intercellular Communication | Colonoscopic biopsy specimens showed nonspecific inflammation in 1 case; however, they showed only granulomatous inflammation in a second case and granulomas associated with fungal hyphae in a third. | 19961248 |
| Inflammation, Congestive heart failure | Altered Intercellular Communication | Congestive heart failure (CHF) has been associated with elevated biomarker levels reflecting chronic low-grade inflammation. | 19961288 |
| Inflammation, Simultaneous, Congestive heart failure | Altered Intercellular Communication | Most likely, elevated YKL-40 levels in CHF patients are explained by the presence of concomitant diseases but a role of YKL-40 in low-grade inflammation is not excluded. | 19961288 |
| Inflammation | Altered Intercellular Communication | Cases with an irregularly thickened and/or calcified cyst wall, presumably due to chronic inflammation of the wall, are rare. | 19961317 |
| Inflammation, Coronary heart disease, atherosclerotic, Choline Dehydrogenase, Mitochondrial | Altered Intercellular Communication | To investigate the association between hemoglobin scavenger receptor (CD163) expression levels on monocytic surfaces and coronary atherosclerotic severity in patients with coronary heart disease (CHD) as well as the roles of CD163 in inflammation and lipidperoxidation. | 19961729 |
| Inflammation, Neoplasms | Altered Intercellular Communication | Current evidence suggests that chronic inflammation is associated with tumor development and progression. | 19961892 |
| Inflammation, Inflammatory disorder | Altered Intercellular Communication | Interleukin-18 (IL-18) plays a central role in inflammation and the immune response, contributing to the pathogenesis and pathophysiology of infectious and inflammatory diseases. | 19961892 |
| Inflammation, Neoplasms, Communicable Diseases, Aneurysm, Traumatic injury | Altered Intercellular Communication | We excluded infection, inflammation, trauma, and neoplasia as causes of the aneurysm. | 19962251 |
| Inflammation, Fibrosis Assessment | Altered Intercellular Communication | Low inflammation and low fibrosis in AAH was associated with the increase of codon 10CC (high producer) and codon 25CC (low producer) genotypes. | 19962351 |
| Aneurysm, Inflammation, Fever, CTCAE | Altered Intercellular Communication | In conclusion, CA dilation only and CA aneurysms differ only in the total duration of inflammation, as measured by the number of days from fever onset to defervescence. | 19962487 |
| Inflammation, Heart failure | Altered Intercellular Communication | Studies indicate that myeloperoxidase (MPO) is associated with disease progression and severity in heart failure (HF), while it may provide a mechanistic link between inflammation and adverse cardiac remodeling. | 19962701 |
| Inflammation, Thrombosis | Altered Intercellular Communication | It has recently been established that platelets have an important role in increasing inflammation, in addition to their main role in hemostasis and thrombosis. | 19962788 |
| ARCN1 gene, Pneumonitis | Altered Intercellular Communication | The nuclear enzyme poly(ADP-ribose) polymerse-1 (PARP-1) has previously been reported to play an important role in lipopolysaccharide (LPS)-induced pulmonary inflammation and is highly activated in COPD patients. | 19962977 |
| Presenile dementia, Inflammation | Altered Intercellular Communication | Hemostasis and inflammation have been implicated in dementia. | 19965782 |
| Inflammation, VAD I protocol, ETV3 wt Allele | Altered Intercellular Communication | Moreover, those with MetS and high inflammation had a still further higher risk of VaD (multivariate adjusted HR, 9.55; 95% CI 1.17 to 78.17) compared with those without MetS and high inflammation. | 19965842 |
| Inflammation, VAD I protocol, ETV3 wt Allele | Altered Intercellular Communication | On the other hand, those with MetS and low inflammation compared with those without MetS and low inflammation did not exhibit a significant increased risk of VaD (adjusted HR, 3.31, 95% CI 0.91 to 12.14). | 19965842 |
| Inflammation, VAD I protocol, ETV3 wt Allele | Altered Intercellular Communication | In our population, MetS subjects had an elevated risk of VaD that increased after excluding patients with baseline undernutrition and selecting MetS subjects with high inflammation. | 19965842 |
| Inflammation, Hyperplasia | Altered Intercellular Communication | Preprocedural inflammation does not affect neointimal hyperplasia following everolimus-eluting stent implantation. | 19966361 |
| Inflammation, Hyperplasia | Altered Intercellular Communication | Our results suggest that preprocedural inflammation does not affect neointimal hyperplasia following EES implantation. | 19966361 |
| Dacryoadenitis | Altered Intercellular Communication | The murine lacrimal gland expresses high levels of macrophage MIF without any evidence of lacrimal gland inflammation. | 19966563 |
| Necrotizing granulomatous inflammation, Acne, Lupus Erythematosus | Altered Intercellular Communication | Acne agminata (lupus miliaris disseminatus faciei, acnitis, papular tuberculid) is a rare form of necrotizing granulomatous inflammation of the dermis that has received scant attention in the ophthalmologic literature. | 19966664 |
| Inflammation | Altered Intercellular Communication | Inflammation is a complex and necessary component of an organism's response to biological, chemical or physical stimuli. | 19967506 |
| Tissue damage, Inflammation, Fibrosis Assessment | Altered Intercellular Communication | Persistent inflammation as a result of prolonged exposure to stimulus or an inappropriate reaction to self molecules can lead to the chronic phase, in which tissue damage and fibrosis can occur. | 19967506 |
| Inflammation, Primary malignant neoplasm, Allergy - Charge Type Reason, Autoimmune Diseases, Atherosclerosis, Diabetes Mellitus, Arthritis, Asthma | Altered Intercellular Communication | Chronic inflammation is reported to contribute to numerous diseases including allergy, arthritis, asthma, atherosclerosis, autoimmune diseases, diabetes, and cancer, and to conditions of aging. | 19967506 |
| Chronicity | Altered Intercellular Communication | The specific profile in a given inflammatory condition is dependent upon species, mechanisms, severity, chronicity, and capacity of the immune system to respond and adapt. | 19967506 |
| Inflammation, Osteoporosis, Penile Diseases | Altered Intercellular Communication | Osteoporosis as a chronic senile disease is associated with inflammation, and the role of inflammatory mediators has been demonstrated in recent years. | 19967563 |
| selenium | Altered Intercellular Communication | CCD in SE may represent injury caused by excessive neuronal transmission from prolonged excitatory synaptic activity via the cortico-pontine-cerebellar pathway. | 19967565 |
| Inflammation | Altered Intercellular Communication | Growing evidence supports a role for inflammation in its pathogenesis but no potential target for intervention has emerged. | 19967568 |
| Chronic Kidney Diseases | Altered Intercellular Communication | Inflammation modifies the association of osteoprotegerin with mortality in chronic kidney disease. | 19967657 |
| Inflammation, Endothelial dysfunction, Chronic Kidney Diseases | Altered Intercellular Communication | As clinical and experimental studies have implicated OPG in atherogenesis, we investigated serum OPG in relation to inflammation, endothelial dysfunction and oxidative stress markers in 265 chronic kidney disease (CKD) stage 5 patients. | 19967657 |
| Inflammation, Cyclophosphamide/Vincristine/Dacarbazine Regimen, Cardiovascular Diseases | Altered Intercellular Communication | Cardiovascular disease (CVD), carotid plaques (n=69) and mortality (5 years) in relation to OPG were also analyzed, and the impact of inflammation on the association of OPG with mortality was evaluated. | 19967657 |
| Inflammation, Endothelial dysfunction, Chronic Kidney Diseases | Altered Intercellular Communication | Elevated OPG levels are associated with surrogate markers of inflammation, endothelial dysfunction, oxidative stress and CVD in CKD patients. | 19967657 |
| Inflammatory abnormality of the eye | Altered Intercellular Communication | Two hundred fifteen patients with noninfectious ocular inflammation observed from initiation of cyclophosphamide. | 19969366 |
| Inflammatory abnormality of the eye, Uveitis, Scleritis | Altered Intercellular Communication | The 215 patients (381 involved eyes) meeting eligibility criteria carried diagnoses of uveitis (20.4%), scleritis (22.3%), ocular mucous membrane pemphigoid (45.6%), or other forms of ocular inflammation (11.6%). | 19969366 |
| Meningioma, Inflammation, Brain Neoplasms | Altered Intercellular Communication | The majority of these findings were owing to inflammation (12 of 15); a case of low grade lymphoma was detected; two patients showed focal brain uptake of 18F-choline and were subsequently submitted to magnetic resonance: in one a meningioma and in the other a low-grade brain tumour were diagnosed. | 19972635 |
| Communicable Diseases, Inflammation, Pain Distress Question | Altered Intercellular Communication | There was a significant reduction in pain scores on days 1 and 2 in the patients treated with an absorbable continuous subcuticular suture, and no difference in inflammation or infection. | 19995253 |
| Inflammation, Pseudotumor, Necrosis | Altered Intercellular Communication | Necrosis and inflammation in peri-implant soft tissues have been described in failed second-generation metal-on-metal (MoM) resurfacing hip arthroplasties and in the pseudotumors associated with these implants. | 19995315 |
| Inflammation | Altered Intercellular Communication | Similar results were found for C-reactive protein, a related marker of chronic inflammation. | 19995479 |
| Inflammation, Depression, CTCAE | Altered Intercellular Communication | Adverse childhood experiences and adult risk factors for age-related disease: depression, inflammation, and clustering of metabolic risk markers. | 19996051 |
| Airway structure, Asthma | Altered Intercellular Communication | RATIONALE Airway inflammation in asthma is heterogeneous with different phenotypes. | 19996343 |
| Inflammation, Malnutrition, Helminthiasis, Anemia, Malaria | Altered Intercellular Communication | Early helminth infections are inversely related to anemia, malnutrition, and malaria and are not associated with inflammation in 6- to 23-month-old Zanzibari children. | 19996438 |
| Inflammation, Helminths | Altered Intercellular Communication | Although helminths were not associated with inflammation, their association with Hb or MUAC-for-age Z score was modified by inflammation. | 19996438 |
| Intestinal metaplasia, Inflammation, Gland | Altered Intercellular Communication | An experienced pathologist assessed the biopsies for the presence and grade of inflammation, activity, glandular atrophy, intestinal metaplasia, presence and density of H. pylori and presence of lymphoid follicles or aggregates. | 19996618 |
| Inflammation, Prostate carcinoma | Altered Intercellular Communication | Evidence is accumulating indicating that chronic inflammation plays an important role in prostate cancer. | 19996656 |
| Vitritis, Inflammation, Panuveitis | Altered Intercellular Communication | Two other patients, after one injection only, had evidence of inflammation (vitritis or panuveitis) on examination at Week 6. | 19996827 |
| Communicable Diseases, Inflammation | Altered Intercellular Communication | Optimal structural outcome was defined as resolution of inflammation and infection. | 19996830 |
| Inflammation, Retractile Mesenteritis | Altered Intercellular Communication | Sclerosing mesenteritis (SM) is an uncommon disorder characterized by chronic nonspecific inflammation involving the adipose tissue of the mesentery. | 19996846 |
| Foveolar hyperplasia, Gastritis, Hypertrophic | Altered Intercellular Communication | Biopsies of the stomach showed marked foveolar hyperplasia with active inflammation and gland changes consistent with Menetrier disease. | 19996862 |
| Inflammation, Intracranial Aneurysm | Altered Intercellular Communication | Inflammation and activation of the complement system in the intracranial aneurysm (IA) wall predispose to IA rupture. | 19997064 |
| Inflammation, Coronary Artery Disease | Altered Intercellular Communication | Environmental exposures filtered through the genetic make-up of each individual alter the transcriptional repertoire in organs central to metabolic homeostasis, thereby affecting arterial lipid accumulation, inflammation, and the development of coronary artery disease (CAD). | 19997623 |
| Retinal Diseases | Altered Intercellular Communication | Inflammation affects the formation and the progression of various vitreoretinal diseases. | 19997642 |
| Inflammation, Retinal Diseases | Altered Intercellular Communication | Major three factors: IL-6, IL-8, and MCP-1 were strongly correlated with each other indicating a common pathway involved in inflammation process in vitreoretinal diseases. | 19997642 |
| Hyperlipidemia, Inflammation | Altered Intercellular Communication | Our results indicate that improvement of insulin resistance, lipidemia, and blood pressure as well as reduction of systemic inflammation after bariatric surgery were associated with the increase of serum NO concentration. | 19997784 |
| Hematoxylin and eosin stain method, Inflammation | Altered Intercellular Communication | H&E and immunohistochemical stained slides were reviewed for the presence of inflammation, ganglion cells, and interstitial cells of Cajal (ICCs). | 19997975 |
| Gastroparesis, Congenital neurologic anomalies, Inflammation | Altered Intercellular Communication | Thus, histologic abnormalities in gastroparesis are heterogeneous and include myenteric inflammation, decreased innervation, and reduction of ICCs. | 19997975 |
| Pain Distress Question, Inflammation | Altered Intercellular Communication | The study confirms that the target medication provides a safe and rapid pain reduction and improvement of inflammation in very young children suffering from painful acute inflammatory ear conditions. | 19998578 |
| Histiocytosis, Langerhans-Cell | Altered Intercellular Communication | [A case of Langerhans cell histiocytosis coincident with severe external ear canal inflammation]. | 19999153 |
| Histiocytosis, Langerhans-Cell, Inflammation | Altered Intercellular Communication | We report a case of Langerhans cell histiocytosis (LCH), a rare disease caused by the proliferation of abnormal Langerhans cells, coincident with severe external ear canal inflammation. | 19999153 |
| Histiocytosis, Langerhans-Cell, Inflammation, Temporal bone structure | Altered Intercellular Communication | LCH should therefore be considered in the case of a patient with severe external ear canal inflammation coincident with temporal bone erosion. | 19999153 |
| Adenocarcinoma, Inflammation, Tuberculosis, Granulomatous inflammation | Altered Intercellular Communication | Eighteen cases (40%) showed non specific chronic inflammation, 10 (22.2%) cases showed caseating granulomatous inflammation suggestive of tuberculosis and 6 (13.3%) cases showed metastatic adenocarcinoma. | 19999215 |
| Inflammation, Low Vision, diabetic, Uveitis | Altered Intercellular Communication | Diabetic patients presenting with uveitis, whatever the aetiology, may have severe inflammation, reduced vision, and poor glycaemic control. | 20001257 |
| Intraocular inflammation, Mucopolysaccharidosis I | Altered Intercellular Communication | MPS was able to control intraocular inflammation without relapse in 30 patients (85.7%). | 20001262 |
| Inflammation | Altered Intercellular Communication | Its synthesis is up-regulated in chronic inflammation and iron excess. | 20002304 |
| Hepatitis | Altered Intercellular Communication | Our results suggest that HBV infection and liver inflammation are independently associated with ICC development. | 20002305 |
| Inflammation, Asthma, Atopy | Altered Intercellular Communication | Markers of eosinophilic and neutrophilic inflammation in bronchoalveolar lavage of asthmatic and atopic children. | 20002661 |
| Inflammation, Asthma, MS4A2 wt Allele | Altered Intercellular Communication | Eosinophilic, but also neutrophilic, inflammation has been described in asthma, but the relationship with atopy was incompletely investigated. | 20002661 |
| Inflammation, Asthma | Altered Intercellular Communication | This pattern of inflammation was observed in both preschool and school-aged asthmatic children. | 20002661 |
| Inflammation, Asthma, Atopy | Altered Intercellular Communication | This study suggests that markers of eosinophilic, but not neutrophilic inflammation, are increased in asthmatic children and also in atopic children without asthma. | 20002661 |
| Inflammation, Epithelial metaplasia | Altered Intercellular Communication | Epithelial metaplasia is a phenomenon where a native mucosal cell type is replaced by another due to altered stem cell differentiation, usually as the result of long-standing injury or inflammation. | 20003139 |
| Inflammation, Chronic Kidney Diseases | Altered Intercellular Communication | The role of 25-hydroxyvitamin D deficiency in promoting insulin resistance and inflammation in patients with chronic kidney disease: a randomised controlled trial. | 20003316 |
| Inflammation, Endothelial dysfunction | Altered Intercellular Communication | The current study indicates an independent relationship between high-fat as well as low-fat dairy consumption, not total dairy intake, and some markers of inflammation and endothelial dysfunction. | 20003635 |
| Inflammation, Liver carcinoma, Hepatitis B, Malignant Neoplasms, FAM126A gene | Altered Intercellular Communication | Hepatocellular carcinoma (HCC) is a frequent malignancy with a high rate of mortality, and the hepatitis B and C viruses are considered major etiological factors associated with the development of chronic inflammation. | 20003764 |
| Meckel Diverticulum, Orchitis, Perforation (observation), Intraabdominal hemorrhage | Altered Intercellular Communication | [Perforation of Meckel's diverticulum with intraabdominal hemorrhage and periappendicular inflammation]. | 20003860 |
| Inflammation | Altered Intercellular Communication | Haemoperitoneum, perforated MD and peri-appendicular inflammation were found during laparotomy. | 20003860 |
| Airway structure, Sleep Apnea, CTCAE, Obesity | Altered Intercellular Communication | Systemic and airway inflammation in sleep apnea and obesity: the role of ICAM-1 and IL-8. | 20004360 |
| Airway structure, Osage language | Altered Intercellular Communication | The data obtained confirm the occurrence of an ICAM- and IL-8-mediated neutrophilic airway inflammation in both OSA and obese patients. | 20004360 |
| Inflammation, Comorbidity, Obesity, Osage language | Altered Intercellular Communication | The degree of inflammation, which seems to worsen in cases of comorbidity (OSA and obesity), is likely to be responsible for the increased risk of developing cardiovascular events observed in these subjects, and therefore, it deserves to be elucidated even more. | 20004360 |
| Inflammation, Primary malignant neoplasm, Crohn Disease | Altered Intercellular Communication | Significant morbidity can result from perineal wounds, particularly if the tissue has been partially devitalized after radiotherapy and extensive resection for cancer or chronic inflammation which may occur in Crohn's disease. | 20004444 |
| Inflammation, Growth Disorders | Altered Intercellular Communication | Stunting, adiposity, and low-grade inflammation in African adolescents from a township high school. | 20005466 |
| Inflammation, Growth Disorders | Altered Intercellular Communication | An association between adiposity and stunting and between adiposity low-grade inflammation was found in this study. | 20005466 |
| Osteopenia | Altered Intercellular Communication | Our data therefore suggest that in bone cells of CF patients, the loss of CFTR activity may result in an increased inflammation-driven bone resorption (through both the reduced OPG and increased PGE(2) production), and thus might contribute to the early bone loss reported in young children with CF. | 20005786 |
| Inflammation, Hepatitis B | Altered Intercellular Communication | Hepatitis B virus overexpresses suppressor of cytokine signaling-3 (SOCS3) thereby contributing to severity of inflammation in the liver. | 20005910 |
| Hepatitis | Altered Intercellular Communication | Increased expression of SOCS3 protein was identified in liver specimens from patients with chronic HBV-infection and this correlated with the severity of liver inflammation. | 20005910 |
| vascular inflammations | Altered Intercellular Communication | Increasing evidence indicates that CD40-CD40 ligand interactions constitute an important mediator for vascular inflammation. | 20006362 |
| Inflammation, Tumor necrosis | Altered Intercellular Communication | Chronic inflammation, characterized by increased serum levels of tumor necrosis factor-alpha, interleukin-6, C-reactive protein, and plasminogen activator inhibitor-1, and the presence of inflammatory-related diseases, are seen commonly in aging. | 20006787 |
| Inflammation | Altered Intercellular Communication | Both the dysregulation of immune cells and phenotypic changes in parenchymal cells may contribute to chronic inflammation in aging. | 20006787 |
| Inflammation | Altered Intercellular Communication | Oxidative stress, via activation of p38 and c-Jun N-terminal kinase and induction of cell senescence, is likely to play a critical role in inflammation. | 20006787 |
| Inflammation | Altered Intercellular Communication | Endoplasmic reticulum stress also may be present in aging and be involved in inflammation. | 20006787 |
| Inflammation | Altered Intercellular Communication | Advanced glycation end products also are important contributors to inflammation in aging. | 20006787 |
| glycation, Inflammation | Altered Intercellular Communication | Because the kidney is a major site for the excretion, and perhaps the degradation, of advanced glycation end products and small inflammatory molecules, reduced renal function in aging may promote oxidative stress and inflammation. | 20006787 |
| Inflammation | Altered Intercellular Communication | Chronic inflammation in turn may potentiate the initiation and progression of lesions in the aging kidney. | 20006787 |
| Inflammation | Altered Intercellular Communication | Aging is characterized by increasing inflammation and oxidant stress (OS). | 20006791 |
| Reduced Device Function, Inflammation | Altered Intercellular Communication | The build-up of AGEs with reduced renal function could contribute to inflammation, increased oxidant stress, and accumulation of AGEs in aging. | 20006791 |
| Inflammatory abnormality of the eye, Uveitis | Altered Intercellular Communication | Patients with uveitis at 4 academic ocular inflammation subspecialty practices. | 20006905 |
| Inflammation | Altered Intercellular Communication | Data obtained in mice, together with the fact that AGP levels largely exceeded gimatecan plasma concentrations, suggest that the increased gimatecan levels in patients with high AGP levels are not related to the binding of the drug to AGP with consequent reduced tissue drug distribution, but possibly to other mechanism associated with inflammation being AGP simply a marker of the inflammation process. | 20007015 |
| Inflammation, Chronic Kidney Diseases, Atrial Fibrillation by ECG Finding | Altered Intercellular Communication | Chronic kidney disease (CKD) increases systemic inflammation, which is implicated in development and maintenance of atrial fibrillation (AF); therefore, we hypothesized that the prevalence of AF would be increased among nondialysis patients with CKD. | 20007681 |
| Inflammation, Hyperglycemia, Diabetes Mellitus | Altered Intercellular Communication | Poor glycemic control in Type 1 diabetes (T1DM) causes long-term cardiovascular complications, at least in part via chronic, low-grade inflammation associated with recurrent hyperglycemia. | 20007854 |
| Airway structure | Altered Intercellular Communication | Fraction of exhaled nitric oxide (Fe(NO)) is regarded as a marker of airway inflammation. | 20007926 |
| Airway structure | Altered Intercellular Communication | The results also support the hypothesis that increased level of Fe(NO) among subjects without respiratory symptoms is a sign of subclinical airways inflammation. | 20007926 |
| Lymphohistiocytosis, Hemophagocytic | Altered Intercellular Communication | Hemophagocytic lymphohistiocytosis (HLH), which has many genetic causes, is characterized by multi-system inflammation. | 20008190 |
| Inflammation, Atrial Fibrillation by ECG Finding | Altered Intercellular Communication | Although clinical studies have suggested a link between inflammation markers and atrial fibrillation (AF), it is still unclear whether local immunologic responses actually exist in human atria during AF. | 20009387 |
| Inflammation | Altered Intercellular Communication | Of these patients, 7 developed BRONJ with BP treatment, after tooth extraction or acute dental inflammation. | 20009460 |
| Inflammation | Altered Intercellular Communication | Treating dental inflammation before prescribing BP prevented the development of BRONJ. | 20009460 |
| Inflammation | Altered Intercellular Communication | We focused our investigation on determining VEGF gene expression and characterizing the different genes, mediators of inflammation and adipogenesis, and which are known to play a relevant role in angiogenesis regulation. | 20011601 |
| Inflammation, Mass in breast | Altered Intercellular Communication | Patients typically present with a firm breast mass, often associated with inflammation of the overlying skin. | 20012050 |
| Inflammation | Altered Intercellular Communication | The expression of pro-inflammatory cytokines such as IL-8, IL-6, MIP-1b, and MCP-1 suggests that T and B cells, macrophages and neutrophils modulate joint inflammation by an immune response. | 20012054 |
| Inflammation, Diabetes Mellitus | Altered Intercellular Communication | We also explore the role of diabetes mellitus in the pathogenesis of malakoplakia and compare the relationship between malakoplakia and xanthogranulomatous inflammation, which are closely related to each-other on both clinical and morphologic grounds. | 20012360 |
| Inflammation, diabetic, Diabetes Mellitus, Diabetic Retinopathy, Cardiac complication | Altered Intercellular Communication | Significantly elevated levels of hsCRP in diabetic patients with the presence of diabetic retinopathy compared with patients without diabetic retinopathy providing a link between inflammation and the development of microvascular complication of diabetes. | 20012460 |
| Inflammation, Complications of Diabetes Mellitus | Altered Intercellular Communication | The link between the antioxidant concentration, inflammation and the development of diabetes complications needs further longitudinal studies in order to confirm our findings. | 20012460 |
| Inflammation, Erythema Infectiosum | Altered Intercellular Communication | These data suggest parvovirus B19 infection may be associated with chronic inflammation in some women after the third decade of life. | 20012869 |
| Tumor necrosis, Inflammation, Antiphospholipid Syndrome | Altered Intercellular Communication | Increased level of tumor necrosis factor-a in patients with antiphospholipid syndrome: marker not only of inflammation but also of the prothrombotic state. | 20012959 |
| Inflammation, Thrombosis, Antiphospholipid Syndrome | Altered Intercellular Communication | Connections between inflammation and thrombosis are intriguing, especially in a condition such as an antiphospholipid syndrome (APS), a disease characterized by immune-mediated thrombosis. | 20012959 |
| Trismus, Inflammation, Pain Distress Question | Altered Intercellular Communication | After treatment one patient developed a grade 2 trismus, another showed grade 3 abacterial salivary gland inflammation with severe pain requiring opioid medication. | 20013086 |
| Neurodegenerative Disorders, Primary malignant neoplasm, Inflammation, Disease | Altered Intercellular Communication | Recent studies have shown that the heat-shock response (HSR) contributes to cytoprotection in a number of human diseases including inflammation, cancer, aging, and neurodegenerative disorders. | 20013185 |
| Inflammation, Neoplasms, Specimen Source Codes - Abscess, Ulcer, Erectile dysfunction | Altered Intercellular Communication | In the 18th century, theories about the main factors inducing impotence saw it as an abnormal state of the fibers, a defect in the solid or liquid substances or a bad structure (tumor, inflammation, abscess, ulcer or foreign body). | 20013735 |
| Inflammation | Altered Intercellular Communication | ST2 has been proposed to be a regulator of inflammation and Th1/Th2 balance. | 20014018 |
| Inflammation, Atherosclerosis | Altered Intercellular Communication | Inflammation is an established risk factor for atherosclerosis. | 20014193 |
| Inflammation, Hyperactive behavior, Atherosclerosis | Altered Intercellular Communication | The findings of hyperactive NF-kappaB in aortas may provide a diagnostic parameter for the inflammation that is associated with and may cause atherosclerosis. | 20014193 |
| allergic inflammation | Altered Intercellular Communication | Cholesterol promotes Th2 immunity and allergic inflammation in rodents; whether this occurs in humans is unclear. | 20015326 |
| Hyperglycemia, Inflammation | Altered Intercellular Communication | In postcardiac-arrest (PCA) patients, hyperglycemia is a factor reflecting an unfavorable outcome, and might be caused by the inflammation and stress of "sepsis-like" syndrome. | 20015588 |
| Chronic Obstructive Airway Disease, Pneumonitis | Altered Intercellular Communication | Alveolar cell senescence exacerbates pulmonary inflammation in patients with chronic obstructive pulmonary disease. | 20016134 |
| ARCN1 gene, Inflammation | Altered Intercellular Communication | We tested the hypothesis that alveolar cell senescence contributes to the chronic inflammation that affects the lungs of COPD patients. | 20016134 |
| Inflammation, BALT lymphoma | Altered Intercellular Communication | BALT lymphomas are associated with chronic inflammation, and they are often asymptomatic. | 20016430 |
| Inflammation, Chronic Kidney Diseases | Altered Intercellular Communication | Chronic kidney disease is frequently associated with protein-energy wasting related to chronic inflammation and a resistance to anabolic hormones such as insulin and growth hormone (GH). | 20016461 |
| Inflammation, Chronic Kidney Diseases | Altered Intercellular Communication | Chronic kidney disease is frequently associated with protein-energy wasting related to chronic inflammation and a resistance to anabolic hormones such as insulin and growth hormone (GH). | 20016461 |
| Inflammation, Chronic Kidney Diseases | Altered Intercellular Communication | Chronic kidney disease is frequently associated with protein-energy wasting related to chronic inflammation and a resistance to anabolic hormones such as insulin and growth hormone (GH). | 20016461 |
| Inflammation, Chronic Kidney Diseases | Altered Intercellular Communication | Chronic inflammation associated with chronic kidney disease predicts all-cause and cardiovascular mortality in hemodialysis patients. | 20016471 |
| ARCN1 gene, Inflammation, Chronic Obstructive Airway Disease | Altered Intercellular Communication | Also inflammation of bronchial mucosa during chronic obstructive pulmonary disease (COPD) is likely combined with inflammatory involvement of nasal mucosa. | 20017434 |
| Refractory anemias, Inflammation, Degenerative polyarthritis | Altered Intercellular Communication | The SF and serum CCL2/MCP-1 concentrations are significantly greater in RA than in OA and in hda-RA than in mda-RA; increased SF over serum concentrations suggest that CCL2/MCP-1 is mainly produced locally by activated cells where it may exacerbate and sustain inflammation by attracting proinflammatory leukocytes, predominantly monocytes (Tab. | 20017457 |
| Inflammation, Critical Illness | Altered Intercellular Communication | Although associated with systemic inflammation, the metabolic features of hypovitaminosis C in acutely hospitalized, non-critically ill patients are more consistent with deficiency than with tissue redistribution. | 20018480 |
| Inflammation | Altered Intercellular Communication | Aging is one factor believed to contribute to processes that underlie chronic low-grade inflammation in older adults. | 20018825 |
| Inflammation, Fibrosis Assessment | Altered Intercellular Communication | Functional annotation analysis revealed prominent regulation of hypoxia-associated biological processes in NSC, including angiogenesis, fibrosis, and inflammation. | 20019191 |
| Inflammation, conjunctiva | Altered Intercellular Communication | Increased tear inflammation seemed to coexist with loss of conjunctival epithelial cohesiveness and increased collagenolytic activity, which may explain the conjunctival laxity observed in patients with conjunctivochalasis. | 20019361 |
| Inflammation, Hypoxia, Anemia | Altered Intercellular Communication | Hepcidin synthesis is suppressed by anemia, hypoxia and erythropoiesis, and induced by inflammation. | 20019408 |
| Inflammation, hepcidin, Anemia | Altered Intercellular Communication | Inflammatory cytokines, such as interleukin-6 (IL-6), increase the synthesis of hepcidin, resulting in anemia of inflammation (AI). | 20019408 |
| Inflammation, Diabetes Mellitus, Non-Insulin-Dependent, Obesity | Altered Intercellular Communication | Type 2 diabetes mellitus (T2D) is predicted by central obesity and circulating adipokines regulating inflammation. | 20019678 |
| Inflammation, Tumor necrosis, Diabetes Mellitus, Non-Insulin-Dependent | Altered Intercellular Communication | Subjects with T2D had higher VAT expression of molecules regulating inflammation (tumor necrosis factor-alpha (TNFalpha), macrophage inflammatory protein (MIP), interleukin-8 (IL-8)). | 20019678 |
| Inflammation, Diabetes Mellitus, Non-Insulin-Dependent | Altered Intercellular Communication | In summary, VAT in T2D expresses higher levels of adipokines involved in inflammation. | 20019678 |
| Inflammation, Back Pain | Altered Intercellular Communication | A 19-year-old female patient with back pain was examined using [(18)F]-FDG-PET to detect the source of inflammation. | 20020137 |
| vascular inflammations | Altered Intercellular Communication | A follow-up scan showed residual uptake of [(18)F]-FDG in the thoracic aorta suggesting subclinical vascular inflammation. | 20020137 |
| Communicable Diseases, Inflammation | Altered Intercellular Communication | We describe the first case of cutaneous infection caused by Chaetomium atrobrunneum and Clavispora lusitaniae in a one-and-a-half-year-old boy with acute and severe inflammation around his left eyelid. | 20020214 |
| Inflammation | Altered Intercellular Communication | These observations indicate that adiposity is associated with inflammation and endothelial activation in very early childhood. | 20020578 |
| Inflammation, "Alzheimers Disease", Data types - Address | Altered Intercellular Communication | Inflammation plays a role in the development of Alzheimer's disease (AD). | 20021370 |
| Inflammation, Hypersensitivity, Infection | Altered Intercellular Communication | Thus, it is practically unknown how a healthy active lifestyle could affect low-grade inflammation processes, infections or allergies in young persons. | 20021690 |
| Inflammation, Alopecia | Altered Intercellular Communication | In women without systemic inflammation or other underlying disorders, serum ferritin levels below or equal to 30 ng/mL are strongly associated with telogen hair loss. | 20021982 |
| Inflammation | Altered Intercellular Communication | Inflammation could not account for increased LS since initial liver enzyme counts were only slightly elevated and did not change significantly. | 20022130 |
| Inflammation | Altered Intercellular Communication | Physical examination found visual acuity reduced to light perception without sign of anterior inflammation. | 20022662 |
| ARCN1 gene, Inflammation, Exacerbation | Altered Intercellular Communication | The course of COPD is punctuated by exacerbations, which further increase systemic inflammation, but the risk of vascular events in the postexacerbation period has never been defined. | 20022970 |
| Autoimmune Diseases, Myocarditis | Altered Intercellular Communication | Myocardial inflammation in autoimmune diseases: investigation by cardiovascular magnetic resonance and endomyocardial biopsy. | 20025587 |
| Autoimmune Diseases, Myocarditis | Altered Intercellular Communication | Myocardial inflammation often coexists with different types of autoimmune diseases. | 20025587 |
| Inflammation | Altered Intercellular Communication | In myocardial specimens, histology revealed inflammation in 5/10 (50%) and PCR documented viral or microbial genomes in 8/10 (80%). | 20025587 |
| Autoimmune Diseases, Myocarditis, cardiac symptom | Altered Intercellular Communication | Myocardial inflammation is a common finding in patients with autoimmune diseases and cardiac symptoms. | 20025587 |
| ARCN1 gene, Inflammation | Altered Intercellular Communication | Treatment with VIP may help to decrease the chronic inflammation in the lung of COPD patients. | 20026142 |
| Host defense, Inflammation | Altered Intercellular Communication | Exaggerated inflammation, impaired host defense, and neuropathology in progranulin-deficient mice. | 20026663 |
| Communicable Diseases, Inflammation | Altered Intercellular Communication | PGRN-deficient mice failed to clear Listeria monocytogenes infection as quickly as WT and allowed bacteria to proliferate in the brain, with correspondingly greater inflammation than in WT. | 20026663 |
| Inflammation, GRN wt Allele | Altered Intercellular Communication | Thus, PGRN is a key regulator of inflammation and plays critical roles in both host defense and neuronal integrity. | 20026663 |
| Inflammation, Frontotemporal dementia | Altered Intercellular Communication | FTD associated with PGRN insufficiency may result from many years of reduced neutrotrophic support together with cumulative damage in association with dysregulated inflammation. | 20026663 |
| Crohn Disease, Inflammation | Altered Intercellular Communication | Over the last some years the increasing knowledge on the pathogenesis of Crohn's disease led to the development of a number of biological agents targeting specific molecules involved in gut inflammation, first of all TNF-alpha and its receptors. | 20028325 |
| Inflammation, Non-compliance, Diarrhea | Altered Intercellular Communication | The reasons for dropout were side effects (diarrhea [n = 1], gastric symptoms [n = 9], and inflammation of the mouth [n = 1]) or non-compliance (n = 3). | 20028640 |
| Carcinoma of lung | Altered Intercellular Communication | IRAK-1 is a novel inflammation-related marker and a potential target for lung cancer chemopreventive strategies. | 20028769 |
| Inflammation | Altered Intercellular Communication | Excision biopsy showed granulomatous inflammation involving the lymphatics. | 20029155 |
| Inflammation, Chronic anterior uveitis | Altered Intercellular Communication | Topical and intravitreal corticosteroids were effective in reducing acute inflammation, yet 2 patients went on to have chronic anterior uveitis. | 20029490 |
| Inflammation, Hypoxia, Anemia, hepcidin | Altered Intercellular Communication | Hepcidin is a small defensin-like peptide, the production of which by hepatocytes is modulated in response to anemia, hypoxia, or inflammation. | 20030521 |
| Inflammation | Altered Intercellular Communication | In addition, the presence of low-grade inflammation, more pronounced in anuric patients, and functional iron deficiency may also contribute to the elevated hepcidin. | 20030521 |
| Pneumonitis | Altered Intercellular Communication | Lymphocytes play a crucial role in lung inflammation. | 20030671 |
| Sepsis, Inflammation, Specimen Type - Fistula, Hilar lymph node | Altered Intercellular Communication | Our experience would suggest that in very carefully selected cases where bronchopulmonary contamination from the fistula is minimal or absent, there is no associated inflammation of the tracheobronchial tree and the patient is stable from a respiratory point of view without evidence of sepsis, there may be a role for a trial of conservative management. | 20030856 |
| Pulmonary failure, Inflammation | Altered Intercellular Communication | Patients with early elevated biomarkers of inflammation exhibited higher NGAL, more pulmonary failure, and greater resource utilization. | 20031165 |
| Intraocular inflammation | Altered Intercellular Communication | Severe intraocular inflammation after intravitreal injection of bevacizumab. | 20031229 |
| Intraocular inflammation | Altered Intercellular Communication | To report 5 cases of severe intraocular inflammation that developed after an intravitreal injection of the same lot of bevacizumab. | 20031229 |
| Intraocular inflammation | Altered Intercellular Communication | Incidence of intraocular inflammation, results of bacterial cultures, best-corrected visual acuity (BCVA), and endothelial cell density. | 20031229 |
| Intraocular inflammation, Inflammation | Altered Intercellular Communication | Five (14.3%) of the 35 cases had severe intraocular inflammation, and the inflammation had some characteristics of toxic anterior segment syndrome (TASS). | 20031229 |
| Staphylococcus epidermidis, Vitreous inflammatory cells | Altered Intercellular Communication | Early Staphylococcus epidermidis postoperative endophthalmitis developed 3 days later in the right eye (injected first) with intense vitreous inflammation, limiting visual acuity to light perception. | 20031257 |
| Inflammation, Pathological fracture of vertebra due to osteoporosis, Acute onset pain | Altered Intercellular Communication | Kyphoplasty to treat an osteoporotic vertebral fracture was followed by acute pain with an inflammatory time pattern and laboratory evidence of inflammation. | 20031466 |
| Inflammation, Malignant Neoplasms | Altered Intercellular Communication | A biopsy of the lesion disclosed moderate nonspecific inflammation, with no microorganisms or evidence of malignancy. | 20031466 |
| Inflammation, Cardiovascular Diseases | Altered Intercellular Communication | Our findings highlight biological pathways that may be important in regulation of inflammation underlying cardiovascular disease. | 20031576 |
| Inflammation, Coronary Artery Disease, Atherosclerosis | Altered Intercellular Communication | Because inflammation is considered of crucial importance in the development of atherosclerosis, we aimed to evaluate whether prolactin levels are associated with the occurrence of coronary artery disease (CAD). | 20031611 |
| Vasculitis | Altered Intercellular Communication | Recent studies suggest that C-reactive protein (CRP) reflects vascular wall inflammation and can predict adverse cardiac events. | 20031768 |
| Inflammation, Necrosis | Altered Intercellular Communication | Five patients (21%) developed marginal necrosis within the fragments of the cut off flaps requiring cutaneous plasty; an inflammation of the recipient site occurred in 5 cases (21%). | 20032531 |
| Pneumonitis, Atherosclerosis | Altered Intercellular Communication | In order to explain these effects (today the causality of the relationship is certain) there are many possible factors, particularly regarding particulate exposures: an increase in cardiovascular risk biomarkers (fibrinogen, white blood cells, and platelets), atherosclerosis, chronic inflammation of lung tissues increased by acute exposure, etc. | 20032841 |
| Inflammation, Impaired cognition, Encephalitis | Altered Intercellular Communication | Investigation of HIV-1-associated alterations in brain protein turnover by the ubiquitin-proteasome system was performed by (1) determining proteasome subunit changes associated with persistent brain inflammation due to HIV-1; (2) determining whether these changes are related to HIV-1 neurocognitive disturbances, encephalitis, and viral loads; and (3) localizing proteasome subunits in brain cells and synapses. | 20035054 |
| Hypophysitis, CTCAE | Altered Intercellular Communication | Primary hypophysitis is believed to be a chronic inflammation of the pituitary tissue caused by the autoimmune mechanism. | 20035143 |
| Pneumonitis | Altered Intercellular Communication | Interleukin 1B (IL1B) is involved in pulmonary inflammation induced by environmental or occupational toxins. | 20035239 |
| Inflammation, Carcinoma of lung | Altered Intercellular Communication | Chronic inflammation has been implicated in the development of lung cancer. | 20035239 |
| Refractory anemias, Inflammation, Rheumatoid Arthritis | Altered Intercellular Communication | Angiogenesis is an essential event in the development of synovial inflammation in rheumatoid arthritis (RA). | 20035291 |
| Degenerative polyarthritis, Inflammation, Refractory anemias | Altered Intercellular Communication | Synovial tissue samples were obtained at surgery from patients with osteoarthritis (OA) and RA, and subjected to immunohistochemistry to investigate the expression and distribution of vasohibin-1 relevant to the degree of synovial inflammation. | 20035291 |
| Inflammation | Altered Intercellular Communication | In synovial tissue, there was a significant correlation between the expression of vasohibin-1 and histological inflammation score (p=0.002, r=0.842). | 20035291 |
| Inflammation, atherosclerotic | Altered Intercellular Communication | Endothelin (ET)-1 has been implicated in the atherosclerotic process and during inflammation. | 20036012 |
| Ischemic stroke | Altered Intercellular Communication | Excitatory amino acids and monoaminergic neurotransmitters in cerebrospinal fluid of acute ischemic stroke patients. | 20036703 |
| Brain Injuries | Altered Intercellular Communication | Improved insight in the role of neurotransmitters in acute cerebral ischemic injury may be fundamental for the successful development of novel therapeutic approaches. | 20036703 |
| Ischemic stroke, Cerebrovascular accident | Altered Intercellular Communication | We investigated excitatory amino acids and monoaminergic neurotransmitters in cerebrospinal fluid (CSF) of acute ischemic stroke patients and their relation to stroke characteristics. | 20036703 |
| Calculus of prostate, Inflammation, Prostate | Altered Intercellular Communication | Prostatic calculi are common and are associated with inflammation of the prostate. | 20037598 |
| Inflammation, Carcinogenesis | Altered Intercellular Communication | Recently, it has been suggested that this inflammation may be associated with prostate carcinogenesis. | 20037598 |
| Kidney Failure, Chronic, Inflammation | Altered Intercellular Communication | Inflammation and oxidative stress in end-stage renal disease patients treated with hemodialysis or peritoneal dialysis. | 20037892 |
| palladium, HD Term Type, Inflammation | Altered Intercellular Communication | HD and PD patients show similar degrees of inflammation and oxidative stress activation. | 20037892 |
| Granulomatous inflammation, Vasculitis, CTCAE, Necrosis | Altered Intercellular Communication | The anatomic pathology is characterized by vasculitis, granulomatous inflammation with multinuclear giant cells and necrosis. | 20038886 |
| Inflammation | Altered Intercellular Communication | The levels of all specific ACPAs were elevated in synovial fluid, suggesting that there is local antibody production and/or retention of ACPAs at the site of inflammation governed by RA-predisposing genes. | 20039432 |
| Nonalcoholic Steatohepatitis, Inflammation, Fatty degeneration | Altered Intercellular Communication | A nonalcoholic steatohepatitis activity index was defined which scored the grade of disease activity between 0 and 12 according to four histologic features: steatosis, hepatocyte ballooning, portal inflammation, and lobular inflammation. | 20039768 |
| Uremia, Inflammation | Altered Intercellular Communication | Uremia is associated with inflammation and release of cytokines by lymphomonocytes. | 20040350 |
| ARCN1 gene, Inflammation | Altered Intercellular Communication | Our results support the hypothesis that chronic inflammation and oxidative burden in COPD can lead to DNA damage of the lung epithelial barrier cells, detected at the Microsatellite DNA level. | 20040382 |
| Inflammation, Chronic Kidney Diseases | Altered Intercellular Communication | We conclude that systemic inflammation is relevant to the process that leads to functional loss in older persons and can be validly measured through biologically informed summary of inflammatory markers. | 20041734 |
| Inflammation | Altered Intercellular Communication | The chemokine CXCL13 is known to dictate homing and motility of B cells in lymphoid tissue and has been implicated in the formation of ectopic lymphoid tissue in chronic inflammation. | 20042073 |
| Inflammatory abnormality of the eye | Altered Intercellular Communication | Given sufficient time, mycophenolate mofetil was effective in managing ocular inflammation in approximately half of the treated patients. | 20042178 |
| Inflammation | Altered Intercellular Communication | We hypothesized that chronic inflammation is associated with altered DNA methylation levels within the PTGS2 promoter, with effects on COX-2 mRNA expression. | 20042743 |
| Inflammation | Altered Intercellular Communication | These findings suggest that the chronic persistence of the biofilm and inflammation may be associated with epigenetic changes in local tissues at the biofilm-gingival interface. | 20042743 |
| Inflammation, Refractory anemias, Rheumatoid Arthritis, Crohn Disease, Comorbidity | Altered Intercellular Communication | Systemic inflammation such as rheumatoid arthritis (RA) and Crohn's disease (CD) may be responsible for vascular comorbidity. | 20042802 |
| Inflammation, Fibrosis Assessment | Altered Intercellular Communication | Histopathological examination revealed a proteinaceous mass consistent with drug precipitate enveloped by fibrosis and mild inflammation. | 20043767 |
| Inflammation, Fibrosis Assessment | Altered Intercellular Communication | No association was detected between CCL3L1 copy numbers and histological grades of inflammation or stages of fibrosis. | 20044164 |
| Inflammation, Intracranial Aneurysm | Altered Intercellular Communication | Gene expression profiles in human ruptured and unruptured intracranial aneurysms: what is the role of inflammation? | 20044533 |
| Inflammation, Rupture | Altered Intercellular Communication | Inflammation may participate in the healing process within IA while playing a protective role against IA rupture. | 20044533 |
| Inflammation, Primary malignant neoplasm, Pathology, Cardiovascular Diseases, Immune dysregulation | Altered Intercellular Communication | Dysregulations of the KKS are likely to be involved in pathologies such as inflammation, cancer and cardiovascular diseases. | 20045189 |
| Inflammation, Neoplasms | Altered Intercellular Communication | The roles of chronic inflammation, immunosuppression, and smoking in the pathogenesis of this tumour are briefly discussed. | 20045232 |
| Inflammation, Tissue Adhesions | Altered Intercellular Communication | Peri-cholecystic adhesions including cholecysto-enteric fistulae and acute inflammation were the main reason for difficult dissection. | 20046176 |
| Inflammation | Altered Intercellular Communication | The data support the hypothesis of an inverse association between GH/IGF-I signalling and inflammation, and suggest that the relationship between the IGF-I and inflammation might be more predominant in healthy individuals with a low inflammatory activity. | 20047081 |
| Arthritis, Chondritis of pinna, Nasal chondritis, Inflammatory abnormality of the eye | Altered Intercellular Communication | Characteristic features include auricular chondritis, arthritis, nasal chondritis, ocular inflammation, respiratory tract involvement and audiovestibular damage. | 20049455 |
| Granulomatous inflammation | Altered Intercellular Communication | Granulomatous inflammation is a relatively common finding in routine aspiration cytology of lymph nodes. | 20049975 |
| Inflammation, Asteroids | Altered Intercellular Communication | A transbronchial fine-needle aspiration biopsy (FNAB) of a paratracheal lymph node showed granulomatous inflammation and numerous multinucleated giant cells containing asteroid bodies. | 20049975 |
| Pain Distress Question, Inflammation | Altered Intercellular Communication | This episode was prolonged lasting for approximately 10 weeks and required hospitalization for the management of pain and control of inflammation. | 20051757 |
| Inflammation, Endothelial dysfunction | Altered Intercellular Communication | No correlations were found between capillary density and plasma markers of adiposity, inflammation or endothelial dysfunction. | 20051903 |
| Inflammation, Exophthalmos, Paranasal Sinus Neoplasms | Altered Intercellular Communication | We rarely encounter patients with proptosis, however, it is known that inflammation and extension of paranasal sinus tumors may cause this condition. | 20053515 |
| Inflammation | Altered Intercellular Communication | Diffusion-weighted analysis and MR spectroscopy were consistent with focal inflammation. | 20054691 |
| Inflammation, Asthma | Altered Intercellular Communication | The initial symptoms included bronchial asthma and inflammation of the ethmoid sinuses. | 20054752 |
| Pain Distress Question, Solitary Osteochondroma, Bursitis, Femoracetabular Impingement, Abnormal degeneration | Altered Intercellular Communication | Although solitary osteochondromas have been linked with bursal inflammation and pain, compression on neurovascular structures, and malignant degeneration, they have not previously been associated with femoral acetabular impingement. | 20055356 |
| Inflammation, Alopecia, CTCAE | Altered Intercellular Communication | During her 50s, however, the patient developed new abnormalities with patchy scarring alopecia and perifollicular inflammation. | 20055845 |
| Acute Lung Injury, Critical Illness, Lung Injury, Pneumonitis | Altered Intercellular Communication | We compared the effect of conventional with lower tidal volumes on pulmonary inflammation and development of lung injury in critically ill patients without ALI at the onset of mechanical ventilation. | 20055989 |
| Inflammation | Altered Intercellular Communication | In this study, we investigated the potential for quantifying plaque inflammation by targeting this receptor. | 20056222 |
| Inflammation, Primary malignant neoplasm | Altered Intercellular Communication | Elevated plasma levels of C-reactive protein (CRP), a marker of inflammation, are associated with an increased risk of cancer, but it is unclear whether this association is causal. | 20056955 |
| Inflammation | Altered Intercellular Communication | Lipocalin-2/neutrophil gelatinase-B associated lipocalin (Lcn2/NGAL) is involved in the transport of iron and seems to play an important role in inflammation. | 20057160 |
| Inflammation, Fever, CTCAE, Periaortitis | Altered Intercellular Communication | Persistent high fever and systemic inflammation induced by percutaneous coronary intervention-related periaortitis. | 20057898 |
| Inflammation, Fever, CTCAE, Periaortitis | Altered Intercellular Communication | We report a very rare case that suggests persistent high fever and systemic inflammation might be caused by periaortitis induced by coronary catheterization including percutaneous coronary intervention. | 20057898 |
| Inflammation, Glaucoma, CTCAE | Altered Intercellular Communication | Damage to trabecular meshwork cells (TMC) and retinal ganglion cells (RGC), involving inflammation and apoptosis mechanisms, has been proved in glaucoma. | 20057902 |
| Inflammation, Humor | Altered Intercellular Communication | Inflammation and apoptosis marker levels increase with smoking in the aqueous humor and plasma samples of POAG women. | 20057902 |
| Inflammation | Altered Intercellular Communication | We present the case of a patient with primary SRC complicated by the development of acute inflammation of the appendix. | 20058100 |
| Inflammation | Altered Intercellular Communication | The appendix was notably thickened with an ulcerated wall containing sinus tracts, chronic inflammation, and scarring. | 20058100 |
| Inflammation, Hyperplasia | Altered Intercellular Communication | Histological analysis consistently demonstrated chronic nonspecific inflammation with synovial hyperplasia, proliferation of vessels and fibroblasts, and increased amount of extracellular matrix. | 20058278 |
| Inflammation, Periodontitis, Diabetes Mellitus | Altered Intercellular Communication | Inflammation and iNOS expression were more prominent in the gingiva of the patients with both diabetes and periodontitis. | 20059423 |
| Inflammation, Immune-mediated | Altered Intercellular Communication | CS is often associated with collagen deposition or chronic inflammation in other segments of the gastrointestinal tract as well as other immune-mediated disorders. | 20060071 |
| Inflammation, Tissue Adhesions, Comorbidity | Altered Intercellular Communication | The technique was uniformly applicable irrespective of gender, age, time of presentation, grade of inflammation, adhesions or any comorbidity. | 20060076 |
| Inflammation | Altered Intercellular Communication | Diffuse large B-cell lymphoma associated with chronic inflammation as an incidental finding and new clinical scenarios. | 20062008 |
| Inflammation, Neoplasms | Altered Intercellular Communication | Diffuse large B-cell lymphoma that develops in the setting of long-standing chronic inflammation is typically associated with Epstein-Barr virus, and usually presents as tumor mass involving body cavities, as in pyothorax-associated lymphoma. | 20062008 |
| Inflammation, Lymphoma, Chronic inflammation, B-Cell Lymphomas | Altered Intercellular Communication | The last feature supports the hypothesis that the lymphoma has arisen in a setting of 'local immunodeficiency' as a result of long-standing chronic inflammation in an enclosed space, a characteristic pathogenetic mechanism of diffuse large B-cell lymphoma associated with chronic inflammation. | 20062008 |
| Inflammation | Altered Intercellular Communication | This report shows that it is possible for an extended epidural cystic mass that occurs in Baastrup's disease to change over time through peripheral inflammation into a cyst-containing fibrotic mass. | 20063020 |
| Airway structure, Bronchial Hyperreactivity | Altered Intercellular Communication | IL-13 has been implicated in the development of airway inflammation and hyperresponsiveness. | 20064211 |
| Inflammation, Tuberculosis | Altered Intercellular Communication | Six patients had tuberculosis and 8 were confirmed with chronic inflammation or benign lesion. | 20064673 |
| Inflammation, Carcinoma of lung, Tuberculosis | Altered Intercellular Communication | Based on the RT-nested PCR examination, 41 of 53 patients were positive for the MAGE gene: 34 of 39 patients had lung cancer; 5 of 6 patients had tuberculosis; and 2 of 8 patients had chronic inflammation or benign lesion. | 20064673 |
| Inflammation, Heart failure, physiopathological | Altered Intercellular Communication | These findings suggest that IL-6 may underlie the pathogenetic link between inflammation, LV dysfunction and incipient heart failure. | 20064818 |
| Gastrointestinal inflammation | Altered Intercellular Communication | The Regenerating gene (REG) Ialpha protein, a trophic and/or anti-apoptotic factor, is important in the pathophysiology of gastrointestinal inflammation. | 20065946 |
| Refractory anemias, Inflammation | Altered Intercellular Communication | Most recent studies show that anti-TNFa medication suppresses inflammation and reduces overall activity of RA. | 20066426 |
| Refractory anemias, Inflammation | Altered Intercellular Communication | The results of the study expand perspectives of the use of MPV in conditions associated with high-grade inflammation, particularly RA, for monitoring anti-inflammatory treatment. | 20066426 |
| Sepsis, Inflammation | Altered Intercellular Communication | Patients with sepsis having a high degree of inflammation did not show a positive correlation between the severity of the disease and the changes of Mg. | 20067167 |
| Inflammation, Autofluorescence, Neoplasms | Altered Intercellular Communication | Newly developed autofluorescence (AF) imaging (AFI) endoscopy can detect AF emitted by the gastrointestinal wall and may reliably detect tumors or inflammation that block AF. | 20068309 |
| Inflammation | Altered Intercellular Communication | Low-grade inflammation, more pronounced in anuric patients may also contribute to elevated NGAL. | 20068352 |
| Vasculitis, Metabolic Syndrome X | Altered Intercellular Communication | Metabolic syndrome is associated with intravascular inflammation, as determined by increased levels of inflammatory biomarkers and an increased risk of ischemic atherothrombotic events. | 20069077 |
| Vasculitis, Thrombosis | Altered Intercellular Communication | Evidence suggests that atherothrombosis and intravascular inflammation share predictive biomarkers, including high-sensitivity C-reactive protein, CD40 ligand, P-selectin, and N-terminal pro-brain natriuretic peptide. | 20069077 |
| Inflammation | Altered Intercellular Communication | Transforming growth factor beta (TGFbeta) is important in inflammation, angiogenesis, reepithelialization and connective tissue regeneration during wound healing. | 20069132 |
| Inflammation, Dental Plaque | Altered Intercellular Communication | The hygiene level was evaluated with Silness and Loe plaque index (PI) and inflammation level with Loe and Silness gingival index (GI). | 20069965 |
| Airway structure | Altered Intercellular Communication | Although corticosteroids reduce airway inflammation, in vitro they inhibit proliferation in only non-asthma ASM cells by reducing cyclin D1. | 20070588 |
| Inflammation, MS gene | Altered Intercellular Communication | Acute symptomatic inflammation is a main feature of multiple sclerosis but pathophysiological processes underlying total or partial recovery are poorly understood. | 20071121 |
| Steatohepatitis, Inflammation, Obesity | Altered Intercellular Communication | Furthermore, DBC1-deficient mice were protected from HFD-induced liver steatosis and inflammation, despite the development of obesity. | 20071779 |
| Heart Diseases, Inflammation, Hypertension, CTCAE, Atrial Fibrillation by ECG Finding | Altered Intercellular Communication | The role of inflammation in maintenance of paroxysmal atrial fibrillation (PAF) in patients with hypertension and no other heart disease has not been fully elucidated yet. | 20072146 |
| Airway structure, Asthma | Altered Intercellular Communication | TLR-mediated inflammatory signals contribute to the development and severity of asthma and are not reduced by glucocorticoid treatment, which suggests that a TLR-specific antagonist and glucocorticoid are required for the effective control of airway inflammation in asthmatics. | 20072849 |
| Asthma | Altered Intercellular Communication | The authors undertook this study to explore the hypothesis that TLR-mediated inflammatory signals are important from the perspective of asthma management. | 20072849 |
| Airway structure, Asthma | Altered Intercellular Communication | TLR-mediated inflammatory signals contribute to the development and severity of asthma and are not reduced by glucocorticoid treatment, which suggests that a TLR-specific antagonist and glucocorticoid are required for the effective control of airway inflammation in asthmatics. | 20072849 |
| Inflammation, Cardiovascular Diseases, Cyclophosphamide/Vincristine/Dacarbazine Regimen, Unipolar Depression, Minimal Disseminated Disease | Altered Intercellular Communication | To determine levels of inflammation (ferritin, transferrin and fibrinogen) in major depression (MDD) and comorbid cardiovascular disease (CVD) in an adult population. | 20073117 |
| Inflammation, Neoplasms, Craniopharyngioma, Epithelial cyst | Altered Intercellular Communication | However a good prognostic factor in craniopharyngiomas was observed in older female patients with complete exeresis, small tumors, external epithelium cysts, edematous stroma, inflammation, and absence of atypical cell and mitosis. | 20073441 |
| Inflammation, Lung diseases | Altered Intercellular Communication | Because many lung diseases cause inflammation at different sites of the lung, fractionated sampling of EBC can reduce variability and maintain an anatomical allocation of the exhaled biomarkers. | 20073556 |
| Inflammation, Prostate carcinoma | Altered Intercellular Communication | Magnetic resonance spectroscopic imaging (1H-MRSI) and dynamic contrast-enhanced magnetic resonance (DCE-MRI): pattern changes from inflammation to prostate cancer. | 20073578 |
| Prostatic Intraepithelial Neoplasias, Acute and chronic inflammation, Prostate carcinoma | Altered Intercellular Communication | To assess (1)H-magnetic resonance spectroscopic imaging ((1)H-MRSI) and dynamic contrast-enhanced magnetic resonance (DCE-MRI) features in histologically confirmed prostatic chronic inflammation, prostatic intraepithelial neoplasia (PIN), low grade prostate cancer (LGPCa), and high grade prostate cancer (HGPCa). | 20073578 |
| Inflammation, Prostate carcinoma | Altered Intercellular Communication | Ninety-six men were selected, who showed at histology a diagnosis of chronic inflammation (Group B), high grade (HG) PIN (Group C), or prostate cancer (LGPCa = Group D and HGPCa = Group E). | 20073578 |
| Autoimmune Diseases, Inflammation, Graft-vs-Host Disease | Altered Intercellular Communication | The well-documented involvement of heparanase in the process of inflammation and autoimmunity led us to investigate an association between HPSE gene single-nucleotide polymorphisms (SNPs) and the risk of GVHD. | 20075159 |
| Inflammation, Infection, Atherosclerosis | Altered Intercellular Communication | These results lend support to the notion that past or chronic exposure to common infections, perhaps by exacerbating inflammation, contributes to atherosclerosis. | 20075350 |
| Inflammation, Obesity | Altered Intercellular Communication | Ezetimibe not only reduced the serum LDL-C level but also improved glucose metabolism as well as obesity and inflammation markers. | 20075600 |
| Metabolic Syndrome X, Atherosclerotic lesion | Altered Intercellular Communication | Inflammation contributes to the development of atherosclerotic lesions in the metabolic syndrome. | 20075843 |
| Vitreous inflammatory cells, Hodgkin Disease | Altered Intercellular Communication | We describe a unique case of a patient with an established diagnosis of Hodgkin's lymphoma in clinical remission who later presented with apparent vitreous inflammation. | 20076991 |
| Granulomatous inflammation | Altered Intercellular Communication | A vitreous biopsy (including fortuitously some peripheral retinal fragments) exhibited granulomatous inflammation. | 20076991 |
| Chronic infectious disease, Inflammation, Traumatic injury, Malignant Neoplasms | Altered Intercellular Communication | None had a history or evidence of malignancy, chronic infection or inflammation, or recent trauma. | 20077946 |
| Whooping cough due to unspecified organism, Acute bronchitis, Bronchitis, Asthma, Respiratory Tract Infections | Altered Intercellular Communication | Daily hospital admissions for total respiratory infections or inflammations (RII), total bronchitis and asthma (BA), and total whooping cough and acute bronchitis (TWCAB) for various age groups and ethnicities were obtained for the Auckland Region and compared with climate parameters on daily, monthly and seasonal time scales. | 20078568 |
| Renal Insufficiency, Inflammation, Kidney Diseases | Altered Intercellular Communication | Inflammation has been related to renal disease in non-Hispanic whites, but there are limited data on the role of inflammation in renal dysfunction in African Americans in the community. | 20078870 |
| Inflammation, Kidney Diseases | Altered Intercellular Communication | The study of inflammation in the progression of renal disease in African Americans merits further investigation. | 20078870 |
| Inflammation | Altered Intercellular Communication | The reason might be related to the exposure and inflammation of the local vocal process cartilage. | 20079098 |
| ARCN1 gene, Pneumonitis | Altered Intercellular Communication | (2) The intensity of IL-16 and CXCR3 were correlated with the index of clinical and pulmonary function that suggested pulmonary arterial inflammation might be one of the key factors associated with the progression of COPD, and inhibiting the pulmonary artery inflammation played an important role in prevention and cure of COPD. | 20079227 |
| Inflammatory Bowel Diseases, Inflammation, Arthritis, Collagen-Induced, Experimental Autoimmune Encephalomyelitis | Altered Intercellular Communication | The immunosuppressive function of regulatory B cells has been shown in several murine models of chronic inflammation, including collagen-induced arthritis, inflammatory bowel disease, and experimental autoimmune encephalomyelitis. | 20079667 |
| Inflammation, Uveitis | Altered Intercellular Communication | The FA intravitreal implant provided better control of inflammation in patients with uveitis compared with systemic therapy. | 20079922 |
| Inflammatory abnormality of the eye | Altered Intercellular Communication | Facial rosacea, lid margin, and ocular surface inflammation were documented by photography and graded in a masked fashion. | 20079929 |
| Inflammation, anatomical bulb | Altered Intercellular Communication | There was a significant correlation between serum immunoreactivity and facial rosacea (P = 0.009), lid margin inflammation (P = 0.040), and ocular Demodex infestation (P = 0.048), but not inferior bulbar conjunctival inflammation (P = 0.573). | 20079929 |
| Inflammation, anatomical bulb | Altered Intercellular Communication | There was a significant correlation of facial rosacea with lid margin inflammation (P = 0.016), but not with inferior bulbar conjunctival inflammation (P = 0.728). | 20079929 |
| Communicable Diseases, Inflammation, Vitreous opacities, Hypopyon | Altered Intercellular Communication | The 3 main kinds of recurrence were: (1) recurrent infection from recipient bed to graft, and once recurrent infection invaded the graft, the inflammation progressed more rapidly; (2) white mushroom-shaped hypopyon with anterior chamber recurrence; (3) infection in the posterior chamber and vitreous opacity on posterior segment recurrence. | 20079930 |
| AURKAIP1 gene, Inflammation | Altered Intercellular Communication | Corticosteroids reduce inflammation and restore both digestive enzyme and HCO(3)(-) secretion in patients with AIP by regenerating acinar cells and correcting CFTR localization in pancreatic duct cells. | 20080093 |
| Cataract, Intraocular inflammation | Altered Intercellular Communication | We report two cases of patients who presented with marked intraocular inflammation following uncomplicated cataract surgery. | 20080318 |
| CARCINOMA OF VULVA | Altered Intercellular Communication | The inflammation-based modified Glasgow Prognostic Score in patients with vulvar cancer. | 20080329 |
| Inflammation, CARCINOMA OF VULVA, Cachexia | Altered Intercellular Communication | To evaluate the prognostic potential of the modified Glasgow Prognostic Score (mGPS), known to reflect the degree of tumor-associated inflammation and cachexia, in patients with vulvar cancer. | 20080329 |
| CARCINOMA OF VULVA | Altered Intercellular Communication | Despite being associated with prognosis in a univariate analysis, mGPS cannot be used as an independent inflammation-based predictor for survival in patients with vulvar cancer. | 20080329 |
| Communicable Diseases, Infertility, Inflammation, Fallopian tube obstruction | Altered Intercellular Communication | We present a unique case of an EV infection of the fallopian tube resulting in inflammation, tubal obstruction, and infertility. | 20080362 |
| Communicable Diseases, Inflammation | Altered Intercellular Communication | Pulmonary surfactant phosphatidylglycerol inhibits respiratory syncytial virus-induced inflammation and infection. | 20080799 |
| Inflammation, Metabolic Diseases | Altered Intercellular Communication | Adipocytes synthesize galectin-3 whose deficiency protects from inflammation associated with metabolic diseases. | 20080851 |
| Degenerative polyarthritis, Inflammation, Osteoarthritis, Knee | Altered Intercellular Communication | To assess whether inflammation on ultrasound is predictive of clinical response to intraarticular (IA) corticosteroid injections in patients with knee osteoarthritis (OA). | 20080918 |
| Inflammation, ciliary vesicle | Altered Intercellular Communication | Microvascular endothelial dysfunction occurs early in the development of CV disease and is worsened by inflammation. | 20080919 |
| Inflammation, Anemia | Altered Intercellular Communication | We characterized the relationships between urinary hepcidin, iron status, anemia, and inflammation in 582 patients 65 years or older participating in the InCHIANTI (Invecchiare in Chianti, "Aging in the Chianti Area") study, a population-based study of aging in Tuscany, Italy. | 20081092 |
| Anemia of chronic disease, Anemia | Altered Intercellular Communication | Compared with nonanemic persons, urinary hepcidin (nanograms/milligram of urinary creatinine) was significantly lower in iron deficiency and inflammation anemia compared with no anemia or other anemia types. | 20081092 |
| Inflammation, hepcidin | Altered Intercellular Communication | Future studies should test whether hepcidin production becomes up-regulated only in situations of overt inflammation. | 20081092 |
| Inflammation | Altered Intercellular Communication | It occurs when soft tissue degenerates after a long period of chronic inflammation. | 20081575 |
| Inflammation | Altered Intercellular Communication | Likewise, during acute events of CAD, the number of circulating EPCs increases under the influence of vascular endothelial growth factor (VEGF) and systemic inflammation. | 20082199 |
| Inflammation, Occult chronic type B viral hepatitis, Infectious agent | Altered Intercellular Communication | The high-sensitivity CRP measurement enabled the detection of slight increases in the serum CRP level, which might reflect a minute inflammation by occult infection, and discriminated high-risk patients for infectious events. | 20082574 |
| Myocarditis | Altered Intercellular Communication | The delayed-enhancement CCTA showed patchy epicardial and mid-myocardial enhancement of the wall and apex, consistent with myocardial inflammation. | 20083062 |
| Myocarditis | Altered Intercellular Communication | Delayed-enhancement cardiac magnetic resonance imaging (CMR) performed the following day confirmed patchy, diffuse epicardial hyperenhancement of the lateral wall, septum, and apex consistent with myocardial inflammation. | 20083062 |
| Myocarditis, Myocarditis, CTCAE 5.0 | Altered Intercellular Communication | Delayed-enhancement CCTA has potential utility for simultaneous evaluation of coronary arteries and myocardial inflammation in suspected myocarditis. | 20083062 |
| Inflammation | Altered Intercellular Communication | 15-Deoxy-Delta(12,14)-prostaglandin J(2) (15d-PGJ(2)) is non-enzymatically produced from PGD(2) and plays roles in inflammation and oxidative stress responses. | 20083106 |
| Communicable Diseases, Inflammation, pathologic fistula | Altered Intercellular Communication | Fistulas are likely because of the presence of chronic inflammation or infection and may be seen at MR imaging, CT, or fluoroscopy. | 20083595 |
| Inflammation, Stomach Carcinoma | Altered Intercellular Communication | In conclusion, our results suggest that those who react strongly to inflammation or who have a high host immune response, as reflected by extremely elevated plasma levels of CRP and SAA, are at a high risk to develop gastric cancer. | 20083644 |
| Dysphonia | Altered Intercellular Communication | Although most pediatric dysphonia can be attributed to benign nodules, our results show that inflammatory conditions and benign lesions other than nodules contribute to dysphonia and are often overlooked and undertreated. | 20083783 |
| Granulomatous inflammation | Altered Intercellular Communication | Granulomatous inflammation was observed in the skin biopsy specimen. | 20084402 |
| Granulomatous inflammation, SYNOVITIS, GRANULOMATOUS, WITH UVEITIS AND CRANIAL NEUROPATHIES (disorder), Uveitis, Polyarthritis | Altered Intercellular Communication | The patient was diagnosed with Blau syndrome based on her family history, uveitis, granulomatous inflammation proved by skin biopsy, and polyarthritis. | 20084402 |
| Inflammation, Swelling, Joint tenderness | Altered Intercellular Communication | Eighteen patients with EOA underwent clinical examination for joint tenderness, bony swelling, and inflammation by two independent, blinded assessors. | 20084443 |
| Arthritis, Swelling, Joint tenderness | Altered Intercellular Communication | The inter-observer agreement was moderate for bony swelling and joint tenderness and fair for joint inflammation (kappa = 0.513, 0.448, and 0.402, respectively). | 20084443 |
| Inflammation | Altered Intercellular Communication | The sensitivity and specificity of clinical examination for joint inflammation were 0.12 and 0.95, respectively. | 20084443 |
| Degenerative polyarthritis, Inflammation, Sore to touch, Swelling | Altered Intercellular Communication | Clinical joint counts for bony swelling, tenderness, and inflammation all correlated with functional status, assessed by the functional index for hand osteoarthritis (FIHOA), whereas US joint counts for joint inflammation did not correlate with the FIHOA. | 20084443 |
| Inflammation | Altered Intercellular Communication | US detects more joints with inflammation than clinical examination in patients with EOA. | 20084443 |
| Inflammation, Damage, BDI - Functional Impairment | Altered Intercellular Communication | US can supplement the clinical examination of patients with EOA, as US-detected subclinical joint inflammation might accelerate joint damage and thus functional impairment. | 20084443 |
| Hepatocellular, Inflammation | Altered Intercellular Communication | These results suggest that intracellular Glycer-AGEs play important roles in promoting inflammation and hepatocellular death. | 20084527 |
| Inflammation, Abnormal Epithelial Cell | Altered Intercellular Communication | Thirty sets of initial, adult endoscopic biopsies suspected to be CD with subsequent resections, repeat biopsies with long-term follow-up, and/or other confirmatory laboratory results were analysed by three gastrointestinal pathologists, blinded for the final diagnosis for mucosal architectural changes, epithelial abnormalities, chronic and active inflammation and changes of muscularis mucosae and submucosa. | 20085514 |
| Inflammation, IIeocolitis, Abnormal Epithelial Cell | Altered Intercellular Communication | The majority of initial biopsies (96%) of CD were abnormal with active chronic ileocolitis with a very high proportion (80%) showing the classic combination of abnormal mucosal architecture, epithelial abnormalities and active chronic inflammation. | 20085514 |
| Inflammation | Altered Intercellular Communication | The most sensitive feature was lamina proprial chronic inflammation (sensitivity 92.7%). | 20085514 |
| Inflammation, Plasmacytosis, Abnormal Epithelial Cell | Altered Intercellular Communication | Sensitivity for other features was as follows: active inflammation 87.8%, basal plasmacytosis 82.1%, architectural changes 80.5% and epithelial abnormalities 70.7%. | 20085514 |
| Muscle damage, Myalgia, Inflammation | Altered Intercellular Communication | Branched-chain amino acid supplementation attenuates muscle soreness, muscle damage and inflammation during an intensive training program. | 20087302 |
| Muscle damage, Myalgia, Inflammation, Fatigue | Altered Intercellular Communication | These results demonstrate that BCAA supplementation during an intensive training program effectively reduces the muscle soreness and fatigue sensation, and that the perceived changes could be attributed to the attenuation of muscle damage and inflammation. | 20087302 |
| Inflammation, Carcinoma of lung | Altered Intercellular Communication | SAA levels were predictive of an elevated risk of lung cancer, supporting the general view that inflammation is implicated in lung cancer development. | 20087959 |
| Inflammation, Abscess, Lymphangitis, Edema | Altered Intercellular Communication | Paraffin oil has destructive consequences: skin inflammation, hard oedema, sterile abscesses, diffuse lymphangitis and paraffinomas. | 20089216 |
| prostatitis | Altered Intercellular Communication | Prostate inflammation can lead to an increase in serum prostate specific antigen concentration and confound the use of prostate specific antigen kinetics. | 20089269 |
| Inflammation | Altered Intercellular Communication | Only vacA s1 was significantly associated with more severe inflammation (P=0.02). | 20090217 |
| Eosinophilic granulomatosis with polyangiitis, Orbital Pseudotumor | Altered Intercellular Communication | Diffuse bilateral orbital inflammation in Churg- Strauss syndrome. | 20090494 |
| Inflammation, Eosinophilic granulomatosis with polyangiitis | Altered Intercellular Communication | A diagnosis of diffuse bilateral inflammation in Churg-Strauss syndrome was made and the patient responded dramatically to prednisolone with resolution of systemic and orbital findings. | 20090494 |
| Eosinophilic disorder, Granulomatous inflammation, Eosinophilic inflammation, orbit (eye disorders), Vasculitis, CTCAE | Altered Intercellular Communication | Three years later she developed rapidly worsening orbital disease, marked peripheral eosinophilia, and orbital biopsy showed evidence of granulomatous inflammation with marked eosinophil infiltration and vasculitic changes, and a weakly positive antineutrophil cytoplasmic autoantibody. | 20090494 |
| Eosinophilic disorder, Asthma, Eosinophilic granulomatosis with polyangiitis, Orbital Pseudotumor | Altered Intercellular Communication | Hence, diffuse bilateral orbital inflammation occurring in the setting of asthma and peripheral eosinophilia should raise the possibility of Churg-Strauss syndrome and warrants biopsy as early institution of therapy can reduce both systemic and ophthalmic complications. | 20090494 |
| Granulomatous inflammation, Necrosis | Altered Intercellular Communication | Our 2 patients presented with the typical clinical findings of small papular lesions in which histopathologic examinations disclosed granulomatous inflammation with necrosis associated with inflamed hair follicles. | 20090495 |
| Inflammation, Infection, peripheral blood, Cerebral Ischemia | Altered Intercellular Communication | Only recently it became evident that cerebral ischemia not only leads to brain tissue damage and subsequent local inflammation but also to a dramatic loss of peripheral blood T-cells with subsequent infections. | 20090932 |
| Inflammation | Altered Intercellular Communication | Perivascular carotid inflammation: an unusual case of carotidynia. | 20091034 |
| Inflammation, Thrombosis, Aneurysm | Altered Intercellular Communication | A CT scan of the neck without intravenous contrast showed perivascular inflammation of the left common carotid artery, without evidence of a collection, arterial thrombosis, aneurysm, or dissection. | 20091034 |
| Myocarditis | Altered Intercellular Communication | Based on the inflammatory index, myocardial inflammation was classified into four grades. | 20091145 |
| Inflammation, Malnutrition | Altered Intercellular Communication | When markers of inflammation or malnutrition were adjusted for separately, the association between dK and mortality was attenuated but remained significant. | 20091484 |
| Cessation of life, Inflammation, Malnutrition | Altered Intercellular Communication | After simultaneous adjustment for markers of inflammation and malnutrition, the risk of death associated with the higher dK categories was attenuated, and the overall trend was eliminated. | 20091484 |
| Cessation of life, Inflammation, Malnutrition | Altered Intercellular Communication | Although unadjusted and partially adjusted models suggested a graded association between higher dK and the risk of all-cause death, this association was apparently due to confounding by factors suggesting malnutrition and inflammation. | 20091484 |
| Inflammation, Observation Method - Coagulation | Altered Intercellular Communication | Impact of adopting low sodium diet on biomarkers of inflammation and coagulation: a randomised controlled trial. | 20091486 |
| Inflammation, Vascular Diseases | Altered Intercellular Communication | Epidemiological data suggest that dietary sodium intake may be associated with systemic inflammation: another potential pathophysiological mechanism by which sodium intake may modify vascular disease. | 20091486 |
| Refractory anemias, Rheumatoid Arthritis, Arthritis, Malignant Neoplasms | Altered Intercellular Communication | Rheumatoid arthritis (RA) is characterized by an uncontrolled spread of destructive joint inflammation resembling malignancy. | 20092399 |
| Inflammation, Primary malignant neoplasm | Altered Intercellular Communication | Epidemiological studies have established strong correlation between inflammation and predisposition for cancer. | 20092399 |
| Ocular surface disease, Conjunctivitis, Schirmer Tear Test Strips | Altered Intercellular Communication | Outcome measures were intraocular pressure, success rate, bleb appearance, ocular surface disease index, Schirmer's tear test 1 and conjunctival inflammation. | 20092592 |
| Inflammation | Altered Intercellular Communication | Is inflammation prior to renal transplantation predictive for cardiovascular and renal outcomes? | 20092820 |
| Kidney Failure, Chronic, Inflammation | Altered Intercellular Communication | Markers of non-specific inflammation, such as C-reactive protein (CRP) or leukocyte count are increased in end-stage renal disease patients. | 20092820 |
| Inflammation | Altered Intercellular Communication | Its existence in neutrophils and the enzymatic activity against phospholipids imply a role in the defence against invading microorganisms and in the generation of lipid mediators of inflammation. | 20093120 |
| Inflammation, Drug toxicity, Injury of kidney | Altered Intercellular Communication | Possible mechanisms include chronic immune rejection, inflammation, drug toxicity, and chronic kidney injury from secondary factors. | 20093355 |
| Communicable Diseases, Inflammation | Altered Intercellular Communication | This occurred despite the in situ cilium, which did not act as a nidus for infection or inflammation. | 20093939 |
| vascular inflammations | Altered Intercellular Communication | The CC genotype of the CYP11B2 C-344T polymorphism was associated with an age-dependent increase in the serum CRP level independent of BP, and may contribute to a cardiovascular phenotype by promoting vascular inflammation. | 20094057 |
| Stomatitis, Communicable Diseases, Helicobacter pylori, Gastritis | Altered Intercellular Communication | Gastritis, an inflammation of gastric mucosa, may be due to many pathological factors and infection, such as with Helicobacter pylori. | 20094782 |
| CD55 gene, Heart, In-Stent Restenosis Indicator | Altered Intercellular Communication | Inflammation state before and after PCI are the risk factors for in-stent restenosis, while the levels of TC, LDL-C and non-HDL-C are the important risk factors for other coronary lesion progression. | 20095335 |
| Inflammation, Atheroma | Altered Intercellular Communication | Statins produce hipolipemic and pleotropic effects on markers of inflammation with stabilization of atheromatous plaque. | 20095516 |
| Primary malignant neoplasm | Altered Intercellular Communication | More studies are needed to understand the role of this CR-mediated reduction in sex hormones in modulating the pathogenesis of age-associated chronic diseases such as cancer and the aging process itself. | 20096034 |
| Inflammation, Atherosclerosis, Coronary heart disease, Choline Dehydrogenase, Mitochondrial | Altered Intercellular Communication | Periodontal inflammation has been implicated in atherosclerosis and coronary heart disease (CHD). | 20096894 |
| Degenerative polyarthritis, Inflammation | Altered Intercellular Communication | Because inflammation is involved in the pathogenesis of osteoarthritis (OA), we have analyzed the expression and production of HLA-G molecules in in vitro cultured synovial fibroblasts (SFs) from OA patients and control subjects. | 20097242 |
| Degenerative polyarthritis, Inflammation, Synovial joint structure | Altered Intercellular Communication | The production of HLA-G1 molecules, constitutively expressed by control and OA SFs, is significantly increased in OA, suggesting a possible mechanism to counteract the inflammation of the synovial joints. | 20097242 |
| ARCN1 gene | Altered Intercellular Communication | Measuring exhaled NO at multiple flow rates however, allows to dissect exhaled NO in an alveolar (CAlv,NO) and bronchial (J'aw,NO) fraction, which are claimed to better reflect the bronchial and alveolar inflammation in COPD. | 20097553 |
| Inflammation, Diabetes Mellitus, Non-Insulin-Dependent, Atherosclerosis | Altered Intercellular Communication | Inflammation and the incidence of type 2 diabetes: the Multi-Ethnic Study of Atherosclerosis (MESA). | 20097779 |
| Inflammation, Diabetes Mellitus, Non-Insulin-Dependent | Altered Intercellular Communication | Many studies have documented associations between inflammation and type 2 diabetes incidence. | 20097779 |
| Inflammation, Diabetes Mellitus, Non-Insulin-Dependent | Altered Intercellular Communication | Higher levels of inflammation predict short-term incidence of type 2 diabetes in a multiethnic American sample. | 20097779 |
| Inflammation, hearing impairment, Hyperglycemia, Diabetes Mellitus, Neuralgia | Altered Intercellular Communication | Mechanisms related to neuropathic or microvascular factors, inflammation, or hyperglycemia may be mediating the association of diabetes and hearing impairment. | 20097782 |
| Inflammation | Altered Intercellular Communication | Salzmann nodular degeneration is a disease of uncertain etiology in which inflammation of the ocular surface may play a role. | 20098304 |
| No ocular symptoms, conjunctiva, Conjunctivitis, Structure of corneal epithelium | Altered Intercellular Communication | ProKera was inserted in both eyes at day 10 after onset of ocular symptoms in a 5-year-old boy suffering from acute TEN, manifesting conjunctival inflammation, large conjunctival defects, pseudomembrane formation, and total corneal epithelial defects. | 20098313 |
| Conjunctivitis | Altered Intercellular Communication | However, because ProKera only covered the cornea and perilimbal conjunctiva, these 2 eyes still showed some conjunctival inflammation several months after discharge from the hospital. | 20098313 |
| Inflammation, "Alzheimers Disease", Cell body of neuron, Data types - Address | Altered Intercellular Communication | Inflammation, insoluble protein deposition and neuronal cell loss are important features in the Alzheimer's disease (AD) brain. | 20098622 |
| Inflammation | Altered Intercellular Communication | These results suggest that S100a9 induced by Abeta or CT contributes to cause inflammation, which then affects the neuropathology including amyloid plaques burden and impairs cognitive function. | 20098622 |
| Inflammatory abnormality of the eye | Altered Intercellular Communication | At the moment of evaluation, ocular inflammation was quiescent in all the patients. | 20099233 |
| Leucocytic infiltrate, Corneal Neovascularization, Inflammatory abnormality of the eye | Altered Intercellular Communication | The absence of inflammatory cell infiltration may be explained by the prolonged control of ocular inflammation in our patients, which may also have limited stimuli for corneal neovascularization. | 20099233 |
| Intraocular inflammation | Altered Intercellular Communication | After 1 week of steroids, visual acuity and intraocular inflammation improved significantly. | 20099238 |
| Giant Cell Arteritis, Arteritis | Altered Intercellular Communication | Diagnostic value of T2-weighted imaging for the detection of superficial cranial artery inflammation in giant cell arteritis. | 20099359 |
| Inflammation, Lobular Endocervical Glandular Hyperplasia | Altered Intercellular Communication | Possible relationship between chronic inflammation and pyloric metaplasia in a patient with lobular endocervical glandular hyperplasia. | 20099512 |
| Inflammation, Hyperplasia | Altered Intercellular Communication | The histological findings, in relation to the previous cesarean section suggest that the ectopic pyloric hyperplasia in the present case could represent a heteroplastic or metaplastic process due to a multidirectional differentiation of cervical glands during chronic inflammation by foreign bodies. | 20099512 |
| Chronic abdominal pain, Weight decreased, Fever, CTCAE, Inflammation | Altered Intercellular Communication | She was hospitalized due to fever with deterioration of her general condition (more than 10% of body weight loss) and chronic abdominal pain with inflammation. | 20099679 |
| Schizophrenia | Altered Intercellular Communication | Cortical GABA deficits that are consistently reported in schizophrenia may reflect an etiology of failed normal postnatal neurotransmitter maturation. | 20100621 |
| palladium, Inflammation | Altered Intercellular Communication | The change in PSTR during the first year of PD is related to PDE IL-6 AR, which may represent intraperitoneal inflammation; however, there does not seem to be a close association between PSTR and the degree of systemic inflammation. | 20100731 |
| Inflammation | Altered Intercellular Communication | These results suggest that income explains the association between education and peripheral inflammation. | 20100883 |
| Inflammation | Altered Intercellular Communication | In short, the reason that higher education is linked to reduced peripheral inflammation is because it reduces the risk for low income status, which is what is directly associated with reduced peripheral inflammation. | 20100883 |
| Optimism, Inflammation, Atherosclerosis | Altered Intercellular Communication | Association of optimism and pessimism with inflammation and hemostasis in the Multi-Ethnic Study of Atherosclerosis (MESA). | 20100888 |
| Inflammation, Refractory anemias, Chronic Obstructive Airway Disease, Chronic inflammatory disorder, Asthma, Depressed mood | Altered Intercellular Communication | Although histone deacetylase (HDAC) inhibitors (HDACis) demonstrate therapeutic effects in animal models of chronic inflammatory disease, depressed macrophage HDAC activity in patients with asthma, chronic obstructive pulmonary disease, or RA may contribute to inflammation in these diseases, potentially contraindicating the therapeutic administration of HDACis. | 20100935 |
| Refractory anemias, Inflammation | Altered Intercellular Communication | Our study identifies redundant, but essential, roles for class I/II and sirtuin HDACs in promoting inflammation, angiogenesis, and cell survival in RA. | 20100935 |
| ovarian neoplasm, Inflammation | Altered Intercellular Communication | An extensive multiple-pathway assessment found evidence that inherited differences may play a role in outcome of ovarian cancer patients, particularly in genes within the angiogenesis and inflammation pathways. | 20103664 |
| Inflammation, Disorder of skeletal muscle, Heart failure | Altered Intercellular Communication | Low 25-hydroxyvitamin D levels, commonly found in older patients with heart failure, may contribute to the chronic inflammation and skeletal myopathy that lead to poor exercise tolerance. | 20103775 |
| Inflammation, Pseudotumor, Neoplasms | Altered Intercellular Communication | An inflammatory pseudotumor of the spleen is a rare benign tumor and designated as mass-like lesions with histologic features of nonspecific inflammation and mesenchymal repair although its etiopathogenesis still remains unknown. | 20103878 |
| Inflammation, Primary malignant neoplasm, Cocaine-Related Disorders, Atherosclerosis, Diabetes Mellitus | Altered Intercellular Communication | Since recent investigations have suggested that inflammation possibly contributes to the pathogenesis of age-related disorders including atherosclerosis, cancer, and diabetes mellitus, the term "inflammaging," a combination of "inflammation" and "aging," has been coined. | 20103915 |
| Williams Syndrome | Altered Intercellular Communication | WS may be a good model for analyzing inflammaging. | 20103915 |
| Inflammation, Primary malignant neoplasm, Cocaine-Related Disorders, Atherosclerosis, Diabetes Mellitus | Altered Intercellular Communication | Since recent investigations have suggested that inflammation possibly contributes to the pathogenesis of age-related disorders including atherosclerosis, cancer, and diabetes mellitus, the term "inflammaging," a combination of "inflammation" and "aging," has been coined. | 20103915 |
| Inflammation, Williams Syndrome | Altered Intercellular Communication | Sera from 14 mutation-proven WS patients (ages: 33-70 years) and 21 healthy Japanese adults ages 15 to 95 years were examined with ELISA for soluble Fas ligand (sFasL) to compare conventional inflammation markers. | 20103915 |
| Inflammation, Williams Syndrome | Altered Intercellular Communication | In conclusion, an increased level of serum sFasL in natural aging and WS patients may suggest a common pathophysiological mechanism: inflammation. | 20103915 |
| Inflammation, Malignant Neoplasms | Altered Intercellular Communication | Though difficult, differentiating the occurrence of malignant tumors from worsening chronic inflammation is crucial. | 20103937 |
| Inflammation, Metabolic Syndrome X | Altered Intercellular Communication | Upregulation of monocyte tissue factor activity is significantly associated with low-grade chronic inflammation and insulin resistance in patients with metabolic syndrome. | 20103969 |
| Inflammation, Metabolic Syndrome X, ETV3 wt Allele | Altered Intercellular Communication | The metabolic syndrome (MetS) is a cluster of cardiovascular risk factors closely linked to inflammation and insulin resistance (IR). | 20103969 |
| Inflammation, Tissue Factor | Altered Intercellular Communication | Upregulation of monocyte TF is significantly associated with low-grade inflammation and IR in MetS. | 20103969 |
| Inflammation, Fatty degeneration | Altered Intercellular Communication | Both forms of CK18 significantly correlated with degree of steatosis, lobular inflammation, and ballooning, and showed stronger positive correlations with NAS than serum aspartate and alanine aminotransferase (AST and ALT). | 20104187 |
| Inflammation | Altered Intercellular Communication | Plasma MIC-1 correlates with systemic inflammation but is not an independent determinant of nutritional status or survival in oesophago-gastric cancer. | 20104227 |
| Inflammation | Altered Intercellular Communication | Macrophage inhibitory cytokine-1(MIC-1) is a potential modulator of systemic inflammation and nutritional depletion, both of which are adverse prognostic factors in oesophago-gastric cancer (OGC). | 20104227 |
| Inflammation, Fibrosis Assessment, Hepatitis B | Altered Intercellular Communication | Forty-eight (30.8%) and 39 (25.0%) patients of non-mild chronic hepatitis B were found to have G3-4 inflammation and S3-4 fibrosis, respectively. | 20104760 |
| Inflammation, Cardiovascular Diseases | Altered Intercellular Communication | Hostile individuals with advanced cardiovascular disease may be particularly susceptible to stress-induced increases in sympathetic activity and inflammation. | 20105692 |
| Allergic, Inflammation, Granuloma, Suppuration, Fibrosis Assessment, Granulomatous, Infarction | Altered Intercellular Communication | As per the results, the characteristic histological features were allergic mucin in allergic, fungal ball in chronic non-invasive, sparse inflammation and numerous hyphae in chronic invasive, non caseating granulomas with dense fibrosis in granulomatous invasive, and infarction with suppuration in acute fulminant FRS. | 20107998 |
| Refractory anemias, Inflammation, Paresis | Altered Intercellular Communication | Initiation of rituximab for continuing synovial inflammation led to remission of RA, but no amelioration of muscle weakness was noted. | 20108015 |
| Inflammation | Altered Intercellular Communication | However, the functional outcome was poor because of persistant inflammation of the anterior segment. | 20108572 |
| Pneumonitis | Altered Intercellular Communication | When inhaling medication, it is essential that drug particles are delivered to all sites of lung inflammation, including the peripheral airways. | 20109122 |
| Inflammation | Altered Intercellular Communication | Elevated levels of the BCA-1 and SDF-1alpha and their receptors may account for an increased presence of B cells and their products, contributing to eosinophilic inflammation in patients with CRSwNP. | 20109310 |
| Inflammation, Hemorrhage, Perforation (observation), Intestinal Obstruction | Altered Intercellular Communication | MD may give rise to bleeding, intestinal obstruction and inflammation; however its perforation by a foreign body is an extremely rare life-threatening complication. | 20109374 |
| Functional Disability, Myositis | Altered Intercellular Communication | In order to prevent severe complications and functional disabilities, early aggressive treatments should be considered when muscle inflammation is refractory to ordinary treatment. | 20110203 |
| Inflammation, Atherosclerosis, Coronary heart disease | Altered Intercellular Communication | Markers of atherosclerosis and inflammation for prediction of coronary heart disease in older adults. | 20110287 |
| Inflammation, Hyperparathyroidism | Altered Intercellular Communication | Iron, inflammation, dialysis adequacy, nutritional status, and hyperparathyroidism modify erythropoietic response. | 20110344 |
| Inflammation, Data types - Address | Altered Intercellular Communication | Overall, these findings show that AD-linked dysregulated immune mechanisms exist, which lead to dendritic cell-mediated over-activation of inflammation and impaired antigen presentation, thus supporting the view that immune cell activation could play an important role in AD pathogenesis. | 20110602 |
| Hyperglycemia, Inflammation, Necrosis | Altered Intercellular Communication | Hyperglycaemia at admission was associated with worse cardiovascular risk profile, high levels of necrosis and inflammation biomarkers and low left ventricle ejection fraction. | 20110816 |
| Inflammation | Altered Intercellular Communication | Adipocypte fatty acid-binding protein-4 (FABP4/adipocyte P2) may play a central role in energy metabolism and inflammation. | 20111020 |
| Migraine Disorders, Inflammation | Altered Intercellular Communication | Cytokine polymorphism in patients with migraine: some suggestive clues of migraine and inflammation. | 20113413 |
| Pain Distress Question, Inflammation, Neuropathy | Altered Intercellular Communication | Transient receptor potential vanilloid 2 (TRPV2), one of the members of TRP (transient receptor potential) superfamily of ion channels, has been suggested to contribute to pain associated with inflammation or neuropathy. | 20113837 |
| Inflammation, Hypoxia, Comorbidity, Alteration in nutrition | Altered Intercellular Communication | Notable among these factors are systemic inflammation, nutritional alterations, the use of certain drugs, hypoxia and the presence of comorbidity and/or advanced age. | 20116748 |
| Intraocular inflammation | Altered Intercellular Communication | Four weeks after surgery, visual acuity was restored and there were no signs of intraocular inflammation. | 20117721 |
| Communicable Diseases, Prototheca, Inflammation | Altered Intercellular Communication | Prototheca spp can be considered as saprophytes, and in spite of their frequency in the environment, they are of low virulence and may cause chronic infection with low-grade inflammation in humans. | 20117953 |
| Anxiety, CTCAE 3.0, Asthma | Altered Intercellular Communication | A sample of 195 patients, mostly middle-aged women with moderate/severe asthma, underwent pulmonary function and airway-inflammation tests and were given anxiety rating questionnaires. | 20118439 |
| Airway structure, Anxiety, CTCAE 3.0 | Altered Intercellular Communication | Anxiety was associated with worse subjective asthma outcomes and increased use of medication/healthcare services, but with decreased airway inflammation, and was not associated with lung function. | 20118439 |
| Intraocular inflammation, Fungal endophthalmitis, Decreased translucency, Candida parapsilosis | Altered Intercellular Communication | Early postoperatively, she developed intrastromal opacities, which were thought to be epithelial downgrowth, but progression and increasing stromal and intraocular inflammation required anterior chamber and vitreous tap, which confirmed the presence of Candida parapsilosis, confirming the diagnosis of fungal endophthalmitis. | 20118788 |
| Intraocular Infection, Inflammation | Altered Intercellular Communication | Corneal venting incisions in DSAEK surgery may be a portal of entry for microorganisms, leading to corneal and intraocular infection, and a high index of suspicion is warranted in the presence of stromal infiltrates or inflammation at venting sites. | 20118788 |
| Hepatic inflammation | Altered Intercellular Communication | No significant association was found between CTGF level and the grade of hepatic inflammation (p > 0.05). | 20121404 |
| Inflammation, Interstitial Fibrosis Assessment, Tubular atrophy | Altered Intercellular Communication | Impact of subclinical inflammation on the development of interstitial fibrosis and tubular atrophy in kidney transplant recipients. | 20121731 |
| Interstitial inflammation | Altered Intercellular Communication | The percent with IF/TA score > 2 and interstitial inflammation (Banff i score > 0) was higher in group 2 (16%, p = 0.004) and group 3 (37%, p < 0.0001) compared to group 1 (3%). | 20121731 |
| Chronic inflammation, Atherosclerosis, Obesity, Cardiovascular Diseases | Altered Intercellular Communication | Chronic inflammations, atherosclerosis and obesity, are major risk factors for cardiovascular diseases. | 20122177 |
| Inflammation, Diabetes Mellitus | Altered Intercellular Communication | We hypothesized that exposure to PM causes prothrombotic changes in persons with diabetes, possibly via systemic inflammation. | 20123602 |
| Inflammation, Cyclophosphamide/Vincristine/Dacarbazine Regimen, Cardiovascular Diseases | Altered Intercellular Communication | Traffic exposure may increase cardiovascular disease (CVD) risk via systemic inflammation and elevated blood pressure, two important clinical markers for managing disease progression. | 20123638 |
| Inflammation | Altered Intercellular Communication | Significantly suppressing inflammation with the immunosuppressive drug cyclosporin A did not affect colonization by HP but blocked the induction of altered DNA methylation. | 20124475 |
| Inflammation, Atherosclerosis | Altered Intercellular Communication | In view of discrete associations with cytokines, FMD, beta-blockers and statins, mDCs and pDCs seem to behave differently and may influence inflammation during atherosclerosis in different ways. | 20124992 |
| Refractory anemias, Inflammation, palladium | Altered Intercellular Communication | The relationship between RA and PD disease activities is not clear, but the importance of periodontal treatment in the control of inflammation to avoid tooth extraction is evident. | 20126902 |
| Carcinogenesis, Gastritis | Altered Intercellular Communication | IL-17A, -17F and MIF have a crucial role in the gastric inflammation and carcinogenesis. | 20127054 |
| Carcinogenesis | Altered Intercellular Communication | Polyamines are important in cell growth and wound repair, but have also been implicated in inflammation-induced carcinogenesis. | 20127992 |
| Inflammation, Hypersensitivity, IL13 gene | Altered Intercellular Communication | Allergic rhinitis, a disease that impairs quality of life, is characterized by inflammation due to an allergic reaction. | 20128420 |
| Granuloma, Inflammation, Uveomeningoencephalitic Syndrome | Altered Intercellular Communication | Subretinal granulomatous lesion may present a manifestation of VKH and mean long standing subretinal fluid and inflammation. | 20128649 |
| Inflammation, S100A4 protein, human | Altered Intercellular Communication | The main concern with benign lesions presenting with inflammation is malignant transformation; thus, clinicians need to be more aware of Meyerson phenomenon. | 20128988 |
| Inflammation, Data types - Address | Altered Intercellular Communication | Functionally, this signature highlights genes involved in pathways that were associated with macrophages and lymphocytes within AD patients: Transforming growth factor (TGF-beta) signaling, oxidative stress, innate immunity and inflammation, cholesterol homeostasis, and lipid-raft perturbation, whereas other genes may also provide new insights in the biology of AD. | 20129318 |
| Inflammation, Intramyometrial route | Altered Intercellular Communication | Pathologic diagnosis confirmed an intramyometrial abscess, originating from the wall of the uterus occupying the entire uterine cavity, lined with granulation tissue, foamy macrophages, and chronic inflammation. | 20129341 |
| Inflammation, Pain Distress Question | Altered Intercellular Communication | Glial cell line-derived neurotrophic factor (GDNF) is involved in inflammation and pain, roles which remain to be delineated clinically. | 20129677 |
| Inflammation, Extravasation | Altered Intercellular Communication | Age-related macular degeneration is a multifactorial disease involving inflammation, neovascularization, and vascular leakage. | 20130708 |
| Inflammation, Fibrosis Assessment | Altered Intercellular Communication | Galectin-3 is a recently developed biomarker associated with fibrosis and inflammation, and it may play a role in cardiac remodeling in HF. | 20130888 |
| Sepsis, Inflammation, Septic Shock | Altered Intercellular Communication | PCT results were classed as: 0.5 ng/ml = sepsis unlikely; >or=0.5 to <2 = sepsis possible; >or=2 to <10 = systemic inflammation; >or=10 = septic shock. | 20131075 |
| Sjogrens Syndrome", Inflammation | Altered Intercellular Communication | Increased expression of interleukin-7 in labial salivary glands of patients with primary Sjogren's syndrome correlates with increased inflammation. | 20131250 |
| Inflammation | Altered Intercellular Communication | To characterize the cellular architecture of the tophus and to determine the presence of cytokines implicated in the initiation and resolution of gouty inflammation. | 20131281 |
| Inflammation | Altered Intercellular Communication | The coexpression of IL-1beta and TGFbeta1 suggests that both proinflammatory and antiinflammatory factors present within the tophus contribute to a cycle of chronic inflammation, attempted resolution, and tissue remodeling. | 20131281 |
| Refractory anemias, Inflammation, Rheumatoid Arthritis | Altered Intercellular Communication | Expression of Notch homologues in local tissue inflammation in rheumatoid arthritis (RA) and cultured synoviocytes has been reported, but the expression profile of Notch-related molecules in peripheral lymphocytes in RA remains unclear. | 20132067 |
| Inflammation | Altered Intercellular Communication | Exercise in systemic sclerosis intensifies systemic inflammation and oxidative stress. | 20132073 |
| Inflammation | Altered Intercellular Communication | Basal and exercise-induced inflammation and oxidative stress were correlated with the modified Rodnan skin score. | 20132073 |
| Sample Size Calculation, Inflammation | Altered Intercellular Communication | Although exercise capacity is impaired in patients with SSc, physical activity intensifies the already increased basal levels of systemic inflammation and oxidative stress. | 20132073 |
| Inflammation, Sample Size Calculation | Altered Intercellular Communication | These data support the concept of a role for systemic inflammation and oxidative stress in the ongoing systemic effects of SSc. | 20132073 |
| Inflammation, SERPINB3 wt Allele | Altered Intercellular Communication | It is therefore plausible that functional variants in DNA repair genes and/or genes controlling inflammation and immunological response play a role in determining susceptibility to OSCC. | 20133197 |
| Pain Distress Question, Viral pericarditis, Idiopathic recurrent pericarditis, Myocarditis | Altered Intercellular Communication | Treatment for idiopathic pericarditis and viral pericarditis, which account for about 85% of cases, focuses on pain management and decreasing pericardial inflammation. | 20133530 |
| Inflammatory Bowel Diseases, Inflammation | Altered Intercellular Communication | The CD40/CD40L interaction activates various pathways in immune and nonimmune cells related to inflammation and was shown to be critical for the development of IBD. | 20133813 |
| Carcinogenesis | Altered Intercellular Communication | Accelerated carcinogenesis following liver regeneration is associated with chronic inflammation-induced double-strand DNA breaks. | 20133864 |
| Primary malignant neoplasm, Liver carcinoma, Hepatitis, Chronic, FAM126A gene | Altered Intercellular Communication | Hepatocellular carcinoma (HCC) is the third leading cause of cancer mortality worldwide and is considered to be the outcome of chronic liver inflammation. | 20133864 |
| Inflammation, Neoplastic Cell Transformation | Altered Intercellular Communication | Our aim was to understand the molecular mechanisms linking liver regeneration under chronic inflammation to hepatic tumorigenesis. | 20133864 |
| Primary malignant neoplasm, Hepatocarcinogenesis | Altered Intercellular Communication | Mdr2-KO mice, a model of inflammation-associated cancer, underwent partial hepatectomy (PHx), which led to enhanced hepatocarcinogenesis. | 20133864 |
| Inflammatory abnormality of the eye | Altered Intercellular Communication | Adverse events potentially related to dacetuzumab included cytokine release syndrome symptoms, non-infectious ocular inflammation, and elevated hepatic enzymes. | 20133895 |
| Inflammation, hepcidin | Altered Intercellular Communication | Concentrations of hemoglobin, serum hepcidin and parameters of iron status and inflammation were determined at baseline and 4 weeks after antimalarial treatment. | 20133896 |
| Communicable Diseases | Altered Intercellular Communication | Malnutrition-inflammation score independently determined cardiovascular and infection risk in peritoneal dialysis patients. | 20134162 |
| Increased insulin level, Inflammation, Dyslipidemias, Diabetes Mellitus, Hypertension, CTCAE | Altered Intercellular Communication | However, when adjustments were made for the presence of diabetes, dyslipidemia, hypertension, hyperinsulinemia, and inflammation, WHR was no longer significantly (P>0.41) associated with incident CVD. | 20134327 |
| Communicable Diseases, Inflammation | Altered Intercellular Communication | Therefore, it can be used for the differential diagnosis of the infection, especially in cases of serious inflammation. | 20134373 |
| Inflammation, Fibrosis Assessment, Hepatitis | Altered Intercellular Communication | These were lobular inflammation, portal inflammation, interface hepatitis, and fibrosis. | 20134396 |
| Inflammation, Diabetes Mellitus, Non-Insulin-Dependent, Obesity | Altered Intercellular Communication | High plasma phospholipase A2 activity, inflammation markers, and LDL alterations in obesity with or without type 2 diabetes. | 20134414 |
| Inflammation, Electrocardiogram: myocardial infarction (finding) | Altered Intercellular Communication | [Cytokine and acute phase inflammation reactant levels in men with myocardial infarction]. | 20135880 |
| Fibrosis Assessment, Malnutrition, Pneumonitis | Altered Intercellular Communication | Cystic fibrosis (CF) is characterized by malnutrition, chronic pulmonary inflammation, and oxidative stress. | 20136439 |
| Granuloma Annulare | Altered Intercellular Communication | Granuloma annulare (GA) is a rare disease characterized by granulomatous inflammation of the dermis. | 20136918 |
| Neurogenic Inflammation | Altered Intercellular Communication | Reports on those proximal connections can therefore obviously not extend to mechanoinsensitive C-fibres and do not explain the origin of neurogenic inflammation in humans without prior sensitization. | 20138429 |
| Pneumonitis | Altered Intercellular Communication | Measurement of biomarkers in exhaled breath condensate (EBC) may be useful for monitoring lung inflammation and injury in mechanically ventilated patients. | 20138493 |
| Inflammation, Disease | Altered Intercellular Communication | Subjects with socket inflammation, contracted sockets, or other known lid disorders were excluded. | 20138606 |
| Diabetic Nephropathy, Inflammation, Atherosclerosis, diabetic | Altered Intercellular Communication | Our results suggest that low-grade inflammation, microinflammation, may be a common risk factor for diabetic nephropathy and atherosclerosis in Japanese type 2 diabetic patients. | 20138680 |
| Diffuse Large B-Cell Lymphoma, Chronic inflammation | Altered Intercellular Communication | On the basis of 2008 World Health Organization diagnostic criteria, we believe these cases should be classified as DLBCL associated with chronic inflammation. | 20139760 |
| Diffuse Large B-Cell Lymphoma, Chronic inflammation | Altered Intercellular Communication | However, unlike the characteristically poor prognosis reported in this entity, we hypothesize that the disease resectability in these cardiac sites, in many cases, may allow for a better prognosis than DLBCL with chronic inflammation at other less resectable sites. | 20139760 |
| Communicable Diseases, Inflammation, Neoplasms | Altered Intercellular Communication | PET/CT demonstrated suspected pathologic foci of Fluorine-18 fluorodeoxyglucose (F-18 FDG) uptake in 41 patients (60%), in 38 of these 41 patients (93%) F-18 FDG PET/CT helped in identifying the causal source, including infection in 25 patients, inflammation in 11 patients, a benign neoplasm in 1 patient, and in 1 patient rejection of a pancreas transplant. | 20139818 |
| Degenerative disorder, Traumatic injury | Altered Intercellular Communication | As much as 17 patients suffered from trauma, 5 of degenerative disease, 3 of inflammations and 2 of metastatic disease. | 20140465 |
| Squamous cell carcinoma | Altered Intercellular Communication | [Syndrome of inappropriate secretion of antidiuretic hormone associated with resection of pulmonary squamous cell carcinoma]. | 20141082 |
| DiGeorge Syndrome, Inflammatory abnormality of the eye, Uveitis, 22q11.2 | Altered Intercellular Communication | Uveitis in DiGeorge syndrome: a case of autoimmune ocular inflammation in a patient with deletion 22q11.2. | 20141355 |
| Inflammation | Altered Intercellular Communication | Urokinase receptor (urokinase-type plasminogen activator receptor [uPAR], CD87), a GPI-anchored protein, is considered to play an important role in inflammation and fibrinolysis. | 20142364 |
| Pneumonitis | Altered Intercellular Communication | uPAR-deficient mice intranasally infected with B. pseudomallei showed an enhanced growth and dissemination of B. pseudomallei when compared with wild-type mice, corresponding with increased pulmonary and hepatic inflammation. | 20142364 |
| Inflammation, Prostate carcinoma, Benign prostatic hypertrophy | Altered Intercellular Communication | Biomarkers of systemic inflammation and risk of incident, symptomatic benign prostatic hyperplasia: results from the prostate cancer prevention trial. | 20142396 |
| Inflammation | Altered Intercellular Communication | Results suggest that systemic inflammation or lower levels of soluble receptors that bind inflammatory cytokines increase BPH risk. | 20142396 |
| Restless Legs Syndrome | Altered Intercellular Communication | Selective serotonin reuptake inhibitors have been associated with the risk of restless legs syndrome (RLS), suggesting that dysregulation of serotonergic neurotransmission may provoke or exacerbate RLS. | 20142619 |
| Inflammation | Altered Intercellular Communication | Moreover, secondary inflammation may be identified in PanCa, further complicating diagnosis. | 20143430 |
| Inflammation, Hepatitis B, Liver Cirrhosis | Altered Intercellular Communication | Group I had distinct features compared with group II, including a low frequency of hepatolithiasis (P = 0.000); a high positive rate of serum hepatitis B surface antigen (P = 0.000) and hepatitis B virus (HBV)-associated cirrhosis (P = 0.038); a high frequency of alpha-fetoprotein (> 400 microg/L) (P = 0.011); a low frequency of carbohydrate antigen 19-9 (> 37 U/mL) (P = 0.017); and a high frequency of liver histological inflammation (P = 0.002). | 20143468 |
| Inflammation, Hypertension, CTCAE | Altered Intercellular Communication | We sought to assess weather inflammation is involved in the impaired vascular reactivity induced by ADMA in essential hypertension. | 20144072 |
| Inflammation, Blood Vessel | Altered Intercellular Communication | Probably, the chronic inflammation documented in these patients may be considered the mechanistic link between ADMA and vascular damage. | 20144072 |
| ARCN1 gene, Reduced Device Function, Bronchiectasis, Airway structure, Mucus retention, Exacerbation, Chronic Obstructive Airway Disease | Altered Intercellular Communication | Persistent airway inflammation with mucus retention in patients with chronic airway disorders such as COPD and bronchiectasis may lead to frequent exacerbations, reduced lung function and poor quality of life. | 20144858 |
| Deoxyglucose, vascular inflammations, atherosclerotic | Altered Intercellular Communication | Metabolic assessment of vascular inflammation by 2-[F]fluoro-2-deoxy-D-glucose positron emission tomography (FDG)-PET is a promising new approach for the evaluation of the vulnerability of atherosclerotic plaques. | 20145577 |
| Communicable Diseases, Inflammation, Malignant Neoplasms | Altered Intercellular Communication | Reports were assessed for significant abnormal findings, including malignancy, infectious processes, and chronic inflammation. | 20145929 |
| Inflammation, Allergy - Charge Type Reason | Altered Intercellular Communication | Hyaluronidase allergy: a rare cause of periorbital inflammation. | 20148844 |
| Hemorrhage, Allergy - Charge Type Reason, Communicable Diseases, Orbital Pseudotumor, Acute-Phase Reaction | Altered Intercellular Communication | This case shows that despite being less common than haemorrhage for acute reactions and infection for delayed reactions, allergy can account for orbital inflammation following ophthalmic surgery. | 20148844 |
| Inflammation, Rheumatoid Arthritis | Altered Intercellular Communication | Hypoxia inducible factor-1-alpha (HIF-1alpha) is related to both angiogenesis and inflammation in rheumatoid arthritis. | 20149310 |
| Refractory anemias, Inflammation | Altered Intercellular Communication | Despite the important role of the transcription factor HIF-1alpha in angiogenesis and inflammation, only a few studies on HIF-1alpha expression have been performed in RA patients. | 20149310 |
| Inflammation, Synovitis | Altered Intercellular Communication | The amount of inflammation was determined by counting inflammatory cells, by estimating the proliferation marker Ki67 in inflamed tissue, and by using a recently published synovitis score which gives an accurate estimate of the amount of inflammation present. | 20149310 |
| Refractory anemias, Inflammation | Altered Intercellular Communication | HIF-1alpha expression is strongest in the sub-lining layer of RA synovium and is related to both angiogenesis and inflammation in synovium from RA patients. | 20149310 |
| Refractory anemias, Inflammation | Altered Intercellular Communication | These results thus suggest that HIF-1alpha could serve as an important new therapeutic target in RA, targeting both angiogenesis and inflammation. | 20149310 |
| Inflammation, Pancreatitis, Fibrosis Assessment, Autoimmune Pancreatitis, Mass of pancreas | Altered Intercellular Communication | However, when the biopsy from a pancreatic mass shows dense chronic inflammation and fibrosis and the serum IgG4 level is not available, it presents a diagnostic dilemma whether it represents autoimmune pancreatitis or peritumoral pancreatitis. | 20149413 |
| Inflammation, Pancreatitis, Adenocarcinoma of pancreas, Autoimmune Pancreatitis, Pancreatic Ductal Adenocarcinoma | Altered Intercellular Communication | We performed IgG4 immunohistochemistry on 25 cases of autoimmune pancreatitis-lymphoplasmacytic sclerosing pancreatitis, 7 cases of autoimmune pancreatitis with granulocytic epithelial lesions, 8 cases of nonspecific pancreatitis, 15 cases of pancreatitis associated with pancreatic ductal adenocarcinoma, and 5 biopsies of pancreatic adenocarcinoma with variable inflammation. | 20149413 |
| Inflammation, Pancreatitis | Altered Intercellular Communication | IgG4-positive cells in peritumoral pancreatitis and nonspecific pancreatitis cases were closely associated with malignant glands and areas of acute inflammation in some cases. | 20149413 |
| Microalbuminuria, Inflammation, Metabolic Syndrome X | Altered Intercellular Communication | Ezetimibe ameliorated the status of metabolic syndrome and microalbuminuria, reduced inflammation and oxidative stress, and increased nitric oxide bioavailability in a LDL-chol reduction-dependent and -independent manner. | 20150722 |
| Inflammation, Observation Method - Coagulation | Altered Intercellular Communication | Tissue factor (TF) is important for initiation of coagulation and for the increased thrombin activity observed at sites of inflammation. | 20150920 |
| Inflammation, Hemorrhage, Osteopenia | Altered Intercellular Communication | The following aspects of disease were assessed to describe the peri-implant condition: detectable radiographic peri-implant bone loss and inflammation, the presence of bleeding on probing at a probing depth >or=4 or >or=6 mm, and radiographic peri-implant bone loss assessed at >or=2.0 and >or=3.0 mm. | 20151801 |
| Inflammation, Osteopenia | Altered Intercellular Communication | Peri-implant inflammation was a frequent finding with and without peri-implant bone loss. | 20151801 |
| Inflammation, Periodontitis | Altered Intercellular Communication | These data support the hypothesis that elevated GCF biomarkers of inflammation and bone resorption from a small number of moderate/deep sites have the potential to identify patients who are vulnerable to progressive periodontitis, and SDD may modify that risk. | 20151804 |
| Inflammation, Inflammatory disorder, Atherosclerosis | Altered Intercellular Communication | Atherosclerosis is an inflammatory disease in which systemic inflammation correlates with disease activity. | 20152234 |
| Inflammation, Corneal edema | Altered Intercellular Communication | One day postoperatively, diffuse corneal edema and anterior chamber inflammation were evident. | 20152620 |
| Cataract, Inflammation | Altered Intercellular Communication | To compare the anti-inflammatory efficacy and subjective tolerability of preservative-free and preserved diclofenac 0.1% and preserved ketorolac 0.5% eye drops for prophylaxis and management of inflammation after cataract surgery. | 20152959 |
| Inflammation, Atrial Fibrillation by ECG Finding | Altered Intercellular Communication | Role of inflammation and oxidative stress in atrial fibrillation. | 20153266 |
| Inflammation | Altered Intercellular Communication | Increasing evidence indicates that inflammation and oxidative stress contribute to the pathogenesis of AF, but their role remains poorly defined. | 20153266 |
| Inflammation, Atrial Fibrillation | Altered Intercellular Communication | In addition, whether inflammation and oxidative stress are associated with particular types of AF is unclear. | 20153266 |
| Inflammation | Altered Intercellular Communication | The purpose of this study was to define the role of inflammation and oxidative stress in AF. | 20153266 |
| Inflammation | Altered Intercellular Communication | Inflammatory biomarkers were significantly increased in patients with AF, supporting a strong association between inflammation and AF. | 20153266 |
| Inflammation, Primary malignant neoplasm | Altered Intercellular Communication | Galectin-3 is a carbohydrate binding protein that plays many important regulatory roles in inflammation, immunity and cancer. | 20153309 |
| Inflammation | Altered Intercellular Communication | Early onset chronic inflammation is present in CF. | 20153702 |
| Inflammation | Altered Intercellular Communication | Platelets may contribute to inflammation by cytokine release and interaction with leukocytes. | 20153702 |
| Tissue damage, Inflammation | Altered Intercellular Communication | In CF, platelet proinflammatory activity is increased at very young age already and might promote inflammation and tissue damage. | 20153702 |
| Inflammation, Vasculitis, CTCAE | Altered Intercellular Communication | This endocardial inflammation correlates with vasculitis, which is the principal pathogenetic mechanism of the disease. | 20154032 |
| ARCN1 gene, Inflammation, Hypoxia | Altered Intercellular Communication | The effects of hypoxia on markers of coagulation and systemic inflammation in patients with COPD. | 20154074 |
| ARCN1 gene, Inflammation, Thrombophilia, Hypoxia, Exacerbation, vinyltriethoxysilane | Altered Intercellular Communication | Patients with COPD are also at increased risk of VTE, particularly during exacerbations, possibly because of a hypercoagulable state secondary to hypoxia and/or heightened systemic inflammation. | 20154074 |
| ARCN1 gene, Inflammation, Hypoxia | Altered Intercellular Communication | We investigated the effects of hypoxia on indices of coagulation and systemic inflammation in patients with COPD. | 20154074 |
| ARCN1 gene, Inflammation | Altered Intercellular Communication | This study demonstrates that a 2-h hypoxic challenge in patients with COPD results in coagulation activation in conjunction with an increase in systemic inflammation. | 20154074 |
| Peripheral Vascular Diseases, Inflammation, Endothelial dysfunction | Altered Intercellular Communication | Endothelial dysfunction and inflammation are understood to contribute to the onset of peripheral arterial disease (PAD), and endothelin (ET) may play an important role in this process. | 20154344 |
| Inflammation, Endothelial dysfunction | Altered Intercellular Communication | This study investigated the role of ET in PAD, and its relationships with symptoms, endothelial dysfunction and inflammation. | 20154344 |
| Inflammation | Altered Intercellular Communication | Plasma concentrations of ET in patients with PAD are greatest in early disease; ET concentrations decrease substantially and inflammation arises as disease advances. | 20154344 |
| NDUFAB1 gene | Altered Intercellular Communication | Our data suggest that, in the elderly, inflammation-associated polymorphisms are related to atherogenesis and that the finding of ACP on US scan can be valuable in identifying subjects at risk for CV events, even if they lack traditional cardiovascular risk factors such as an increase in IMT. | 20154512 |
| Rupture, Inflammation | Altered Intercellular Communication | Although the apparent site of the rupture was not obvious, there was a wide area of acute inflammation in the mediastinal adipose tissue. | 20155350 |
| Inflammation, Anterior scleritis, Scleromalacia perforans, Necrotizing | Altered Intercellular Communication | There are three types of anterior scleritis: diffuse, nodular, and necrotizing with and without inflammation (scleromalacia perforans). | 20155432 |
| Inflammation, Ulcerative Colitis | Altered Intercellular Communication | In ulcerative colitis (UC) gut bacteria drive inflammation. | 20155842 |
| Inflammation | Altered Intercellular Communication | The results support the concept that NOD2 risk alleles contribute to impaired regulation of inflammation in the ileum. | 20155851 |
| Ovarian Cysts | Altered Intercellular Communication | This case illustrates that fetal and maternal ovarian cysts may co-exist and could potentially have a similar hormonal etiology. | 20156113 |
| Inflammation, Chronic diarrhea, Colitis | Altered Intercellular Communication | Collagenous colitis (CC) is characterized by chronic watery diarrhea, a macroscopically normal colonic mucosa but typical microscopic inflammation. | 20156310 |
| Inflammatory disease of mucous membrane | Altered Intercellular Communication | Chronic mucosal inflammation of the colon and rectum has earlier been associated with altered visceral sensitivity, but anorectal function has never been reported in cases of CC. | 20156310 |
| Inflammation, Hypersensitivity, Colitis | Altered Intercellular Communication | Collagenous colitis was not associated with rectal hypersensitivity or disturbed anal function despite rectal inflammation. | 20156310 |
| Autoimmune Diseases | Altered Intercellular Communication | Although regulatory T lymphocytes (Tregs) have a pivotal role in preventing autoimmune diseases and limiting chronic inflammatory conditions, they may also block beneficial immune responses by preventing sterilizing immunity to certain pathogens. | 20156359 |
| Inflammation, Obesity | Altered Intercellular Communication | Both, cigarette smoking and obesity were accompanied by subclinical systemic inflammation. | 20156719 |
| Airway structure, Asthma, Chronic Obstructive Airway Disease | Altered Intercellular Communication | Relationship between airway inflammation and remodeling in patients with asthma and chronic obstructive pulmonary disease. | 20156734 |
| ARCN1 gene, Asthma, Chronic Obstructive Airway Disease, Airway structure | Altered Intercellular Communication | Despite a number of important differences in the pathogenesis, course and prognosis of asthma and chronic obstructive pulmonary disease (COPD), these two entities also have common features with airway inflammation being one of them. | 20156734 |
| Inflammation, Rheumatoid Arthritis | Altered Intercellular Communication | Inflammation and microvascular and macrovascular endothelial dysfunction in rheumatoid arthritis: effect of treatment. | 20156948 |
| Refractory anemias, Rheumatoid Arthritis, Inflammation, Endothelial dysfunction | Altered Intercellular Communication | To determine whether abnormalities in microvascular and macrovascular function in rheumatoid arthritis (RA) are associated with plasma markers [von Willebrand factor (VWF)] of endothelial dysfunction and inflammation [C-reactive protein (CRP)] and whether the abnormalities would be altered by treatment. | 20156948 |
| Refractory anemias, Inflammation, Endothelial dysfunction | Altered Intercellular Communication | Endothelial dysfunction and inflammation in RA may contribute to adverse cardiovascular events. | 20156948 |
| Refractory anemias, Inflammation | Altered Intercellular Communication | Patients with RA have abnormal endothelium-independent microvascular function that correlates with inflammation but is not altered by short-term antiinflammatory therapy. | 20156948 |
| Inflammation, Ichthyosis Bullosa of Siemens, Irritable Bowel Syndrome | Altered Intercellular Communication | Inflammation and immune activation have repeatedly been suggested as pathogentic factors in irritable bowel syndrome (IBS). | 20158890 |
| Renal Insufficiency, Inflammation | Altered Intercellular Communication | GDF-15 was consistently related to cardiovascular risk factors and biochemical markers of hemodynamic stress, renal dysfunction, and inflammation. | 20160200 |
| Retinitis Pigmentosa, Neoplasms | Altered Intercellular Communication | Inflammation within index tumors of 236 men undergoing RP from 1996 to 2004 was graded by a single pathologist as grade 0 (absent), 1 (mild: < or =10%), and 2 (marked: >10%). | 20160265 |
| Post-infectious disorder, Dyspepsia, Gastritis | Altered Intercellular Communication | The histological score of chronic gastric inflammation was greater in post-infectious functional dyspepsia versus patients with nonspecific functional dyspepsia or healthy controls. | 20163288 |
| Arthritis, Urticaria | Altered Intercellular Communication | We present a 6 year old boy with chronic urticaria of neonatal onset associated in childhood with features of neurological and joint inflammation. | 20163528 |
| Chronic Infantile Neurological, Cutaneous, and Articular Syndrome, Neurogenic Inflammation, Urticaria | Altered Intercellular Communication | NOMID must be considered in any child with chronic urticaria of neonatal/infantile onset, particularly if associated with joint and/or neurological inflammation. | 20163528 |
| Inflammation, Diabetes Mellitus, Non-Insulin-Dependent | Altered Intercellular Communication | The genotypes -174 GC/CC and -572 GG may confer susceptibility for the development of subclinical inflammation and type 2 diabetes in Mexican families. | 20164544 |
| Synapses, "Alzheimers Disease", Data types - Address | Altered Intercellular Communication | Neurotransmitter system dysfunction and synapse loss have been recognized as hallmarks of Alzheimer's disease (AD). | 20164549 |
| Inflammation, Pterygium Of Conjunctiva And Cornea | Altered Intercellular Communication | The correlation of pterygium cell changes with pterygium activity supports the role of inflammation and its relationship with goblet cells in the pathogenesis of pterygium. | 20164747 |
| Granulomatous inflammation | Altered Intercellular Communication | A portion of the cyst's lining was replaced by granulomatous inflammation resulting from an earlier spontaneous partial rupture. | 20164755 |
| Inflammation, Infection | Altered Intercellular Communication | No deep pin track infections occurred; superficial skin inflammation was seen in 30%. | 20166356 |
| Corneal lesion, Inflammation | Altered Intercellular Communication | The patient presented a corneal lesion with marked superior thinning and no clinical signs of inflammation. | 20168219 |
| Choroidal Neovascularization | Altered Intercellular Communication | The purpose of this study was to report our experience with intravitreal bevacizumab for inflammation-related choroidal neovascularization in two tertiary centers. | 20168273 |
| Choroidal Neovascularization, Uveitis | Altered Intercellular Communication | Ten eyes of 10 patients (range, 14-78 years; mean age, 44 years) with underlying uveitis were treated with intravitreal bevacizumab for inflammation-related choroidal neovascularization from 2006 to 2008. | 20168273 |
| Inflammation, Choroidal Neovascularization, Inflammatory disorder | Altered Intercellular Communication | Intravitreal bevacizumab is an effective treatment for choroidal neovascularization related to inflammatory diseases when inflammation is controlled. | 20168273 |
| Tumor necrosis, Inflammation | Altered Intercellular Communication | Finally, we show that sEpoR is increased in the supernatant of a human erythroleukaemia cell line when stimulated by inflammatory mediators such as interleukin-6 and tumor necrosis factor alpha implying a link between inflammation and erythropoietin resistance. | 20169072 |
| Thrombosis | Altered Intercellular Communication | Acute infection-inflammation and coronary stent thrombosis: an observational study. | 20169424 |
| Inflammation | Altered Intercellular Communication | We present the case of a boy, who suffered inflammation of venous sinuses of cranial basis, when he was 6 years old. | 20169891 |
| Inflammation, Diabetes Mellitus | Altered Intercellular Communication | Plasma interleukin (IL)-1b and IL-6 are markers that predict the risk of inflammation in diabetes. | 20170929 |
| Inflammation | Altered Intercellular Communication | It accompanies local ophthalmological inflammation and its appearance during the course of this disease must be dealt with carefully. | 20171431 |
| Inflammation, Metabolic Syndrome X, ETV3 wt Allele, Cardiovascular Diseases | Altered Intercellular Communication | Metabolic syndrome (MetS) is characterized by low-grade inflammation and confers an increased risk for cardiovascular disease. | 20171637 |
| Inflammation, Ulcer | Altered Intercellular Communication | This disease is characterized by ulcers and signs of acute inflammation on the membranous portion of the vocal folds with a prolonged clinical course. | 20171831 |
| Gastrointestinal inflammation, Protein-Losing Enteropathies | Altered Intercellular Communication | Intestinal inflammation is a component of the pathophysiology of protein-losing enteropathy after the Fontan operation. | 20172140 |
| Inflammation, Degenerative disorder | Altered Intercellular Communication | Inflammation plays an important role in many chronic degenerative diseases associated with aging, and social, economic, and behavioral factors that contribute to inflammation may lead to differential burdens of morbidity and mortality in later life. | 20172904 |
| Inflammation, Health-Related Behavior | Altered Intercellular Communication | Health-related behaviors and usage of medications related to inflammation accounted for substantial proportions of these associations. | 20172904 |
| Inflammation | Altered Intercellular Communication | These results highlight the fundamental causes of inflammation among older adults and suggest pathways through which social disparities in inflammation may be reduced. | 20172904 |
| Inflammation, Critical Illness | Altered Intercellular Communication | Future research focusing on the association between acute systemic inflammation and post-ICU outcome is warranted in order to improve long-term survival of critically ill patients. | 20173056 |
| Parkinson Disease, "Alzheimers Disease | Altered Intercellular Communication | Impaired neurotransmitter release in Alzheimer's and Parkinson's diseases. | 20173332 |
| Sarcoidosis, Inflammatory abnormality of the eye, Intraocular Lymphoma | Altered Intercellular Communication | Although primary intraocular lymphoma should always be in the differential diagnosis of older patients who present with signs of ocular inflammation, ophthalmologists must also consider other etiologies, including sarcoidosis. | 20175273 |
| Intraocular inflammation | Altered Intercellular Communication | To report clinical and epidemiologic findings of 11 patients with severe intraocular inflammation after intravitreal injection. | 20175274 |
| Intraocular inflammation | Altered Intercellular Communication | This is a single-center, retrospective, interventional case series of 11 patients with severe intraocular inflammation after intravitreal injection at 1 referral center. | 20175274 |
| Intraocular inflammation | Altered Intercellular Communication | During the examination period, we identified 11 cases of intraocular inflammation after intravitreal injection. | 20175274 |
| Dermatitis | Altered Intercellular Communication | Right leg magnetic resonance imaging (MRI) showed high signal areas on T(2)-weighted images on the subcutaneous fatty tissue, muscles and bone marrow, suggesting that skin inflammation extended to the bone marrow. | 20175843 |
| Inflammation, Scleroderma | Altered Intercellular Communication | Our observations suggest that MRI examination should be considered in patients with localized scleroderma to evaluate the extension of the inflammation. | 20175843 |
| Inflammation, Candida (fungus) | Altered Intercellular Communication | This case and a similar reported case suggest that Candida can sometimes cause cutaneous inflammation predominantly composed of eosinophils. | 20175854 |
| Inflammation, Immune-mediated | Altered Intercellular Communication | The STAT4 gene encodes a transcription factor which plays an important role in the development of inflammation of many immune-mediated diseases. | 20176035 |
| Inflammation, Vascular System Injuries | Altered Intercellular Communication | Sulfatides may play a physiological role on inflammation in vascular injury and the development of neointimal thickening. | 20176357 |
| Inflammation, Coronary Artery Disease, Atherosclerosis | Altered Intercellular Communication | The crucial role of T helper (Th) cells and chronic inflammation in atherosclerosis and coronary artery disease is no longer controversial. | 20177960 |
| Inflammatory disorder | Altered Intercellular Communication | IFN regulatory factor (IRF)-1 is a pleiotropic transcription factor involved in innate immunity and chronic inflammation disease. | 20177960 |
| Inflammation, Acanthosis, Ulceration, CTCAE, Spongiosis | Altered Intercellular Communication | Histological examination showed spongiosis and acanthosis in the stratum corneum, ulceration and inflammation with prevalently mononucleate cells and septate and branched fungal structures in the epidermis and in dermis. | 20177971 |
| Nonspecific interstitial pneumonia, Fibrosis Assessment, Pneumonia, Interstitial, Interstitial inflammation | Altered Intercellular Communication | Nonspecific interstitial pneumonia (NSIP) was initially defined in 1994 as a histopathologic pattern, characterized by the presence of varying proportions of lung interstitial inflammation and fibrosis, with a temporally uniform lung involvement, that can be found in the presence of a wide variety of clinical and radiologic contexts. | 20178304 |
| Inflammation, Obesity | Altered Intercellular Communication | Telomere length in relation to insulin resistance, inflammation and obesity among Arab youth. | 20178511 |
| Inflammation, Rupture, Dystrophic calcification, Calcinosis, Epithelial cyst | Altered Intercellular Communication | The presence of normal values of calcium and phosphorus along with this spectrum of changes in histology both support the theory that these form by dystrophic calcification of epithelial cysts in a progression that involves inflammation, rupture, calcification and obliteration of the cyst wall. | 20178701 |
| Inflammation, Atherosclerosis | Altered Intercellular Communication | Metabolic activation of monocytes has been suggested to be an important link between chronic inflammation, oxidative stress and the development of atherosclerosis. | 20178722 |
| Inflammatory disease of mucous membrane, Intestinal Diseases, Intestinal Pseudo-Obstruction | Altered Intercellular Communication | The diagnoses were enteropathy in 3, extreme short gut in 1, complex (associated mucosal inflammation and dysmotitlity) in 2, and intestinal pseudo-obstruction in 1. | 20179643 |
| Anxiety, CTCAE 3.0, Inflammation | Altered Intercellular Communication | NPSR1 is expressed in the brain, where it modulates anxiety and responses to stress, but also in other tissues and cell types including lymphocytes, the lungs, and the intestine, where it appears to be up-regulated in inflammation. | 20179762 |
| Inflammation, Fibrosis Assessment, Alcoholic Liver Diseases, Liver Stiffness | Altered Intercellular Communication | To test if inflammation also interferes with liver stiffness (LS) assessment in alcoholic liver disease (ALD) and to provide a clinical algorithm for reliable fibrosis assessment in ALD by FibroScan (FS). | 20180235 |
| Inflammation, prostatitis | Altered Intercellular Communication | Fifty-one (31.5%) of the total specimens presented pathological changes of chronic prostatitis, of which 44 had mild focal stromal, 5 mild focal stromal and periglandular and 2 mild focal periglandular inflammation. | 20180403 |
| Inflammation, Chronic prostatitis | Altered Intercellular Communication | Bacterial inflammation may play an important role in the etiology of chronic prostatitis. | 20180403 |
| Inflammation, Rheumatoid Arthritis | Altered Intercellular Communication | These results suggest that cysteine cathepsins have a major role in inflammation at least in rheumatoid arthritis. | 20180636 |
| Inflammation, Atrophic | Altered Intercellular Communication | Atrophy development was related to age (OR 1.23) and to the severity of chronic inflammation in the corpus mucosa at baseline (OR 8.98). | 20180646 |
| Inflammation, Atrophic | Altered Intercellular Communication | The incidence of atrophy of the corpus mucosa was 1.4 per 100 person years with a positive relation to age and to the degree of chronic inflammation at baseline. | 20180646 |
| Inflammation, Cardiovascular Diseases, Cyclophosphamide/Vincristine/Dacarbazine Regimen, Atherosclerosis | Altered Intercellular Communication | The relationship of serum ferritin with early cardiovascular disease (CVD), particularly atherosclerosis, has not been evaluated extensively, particularly with accounting for inflammation. | 20181783 |
| Inflammation, Atherosclerosis | Altered Intercellular Communication | In conclusion, carotid atherosclerosis was positively associated with serum ferritin in individuals free from subclinical inflammation based on AGP. | 20181783 |
| Presenile dementia, Lewy Bodies, Parkinson Disease | Altered Intercellular Communication | Neurotransmitter changes in dementia with Lewy bodies and Parkinson disease dementia in vivo. | 20181924 |
| Waldenstrom Macroglobulinemia | Altered Intercellular Communication | Immune-related and inflammatory conditions and risk of lymphoplasmacytic lymphoma or Waldenstrom macroglobulinemia. | 20181958 |
| Communicable Diseases, Allergic | Altered Intercellular Communication | We evaluated a wide range of autoimmune, infectious, allergic, and inflammatory conditions. | 20181958 |
| Infarction, Inflammation | Altered Intercellular Communication | Diffusion-weighted imaging showed restricted diffusion in the distal intraorbital segment of the optic nerve, consistent with infarction attributed to compression or inflammation of the vessels serving the optic nerve and retina. | 20182203 |
| Inflammation | Altered Intercellular Communication | A 76-year old man presented with inflammation of the eyelids and underlying orbital soft tissue. | 20182211 |
| Inflammation, Atrophic | Altered Intercellular Communication | A biopsy disclosed inflammation and atrophy of the orbital fat consistent with LEP. | 20182211 |
| Exanthema, Orbital Pseudotumor, Enophthalmos | Altered Intercellular Communication | LEP should be considered in patients with a characteristic rash and orbital inflammation and may cause acquired enophthalmos. | 20182211 |
| ARCN1 gene, Inflammation, Arterial Stiffness | Altered Intercellular Communication | We hypothesised that sub-clinical right (RV) and left ventricular (LV) dysfunction occurs in patients with COPD, related to the severity of airflow obstruction, arterial stiffness and systemic inflammation. | 20185285 |
| Inflammation, Vasculitis, Central Nervous System | Altered Intercellular Communication | Leptomeningeal biopsies of two cases revealed perivascular inflammation, indicating central nervous system vasculitis. | 20185466 |
| Inflammation, Malnutrition, Diabetes Mellitus, Cardiovascular Diseases | Altered Intercellular Communication | These highly fatigued patients exhibited a significantly higher risk for cardiovascular events (hazard ratio: 2.17; P < 0.01), with the relationship independent of the well-known risk factors, including age, diabetes, cardiovascular disease history, and inflammation and malnutrition markers. | 20185601 |
| Inflammation, Diabetes Mellitus | Altered Intercellular Communication | We aimed to investigate whether it could act as a link between low-grade chronic inflammation and diabetes. | 20185737 |
| Inflammation, Non-alcoholic Fatty Liver Disease, Diabetes Mellitus, Non-Insulin-Dependent, Dyslipidemias | Altered Intercellular Communication | Nonalcoholic fatty liver disease is highly prevalent in obese and type 2 diabetic individuals and is strongly associated with dyslipidemia and inflammation. | 20185740 |
| Steatohepatitis, Weight decreased, Inflammation | Altered Intercellular Communication | Addition of ezetimibe to a moderate weight loss diet in obese subjects can significantly improve hepatic steatosis, inflammation, and LDL-apoB-100 metabolism. | 20185740 |
| Inflammation, Retinal Diseases | Altered Intercellular Communication | Age-related macular degeneration: the molecular link between oxidative damage, tissue-specific inflammation and outer retinal disease: the Proctor lecture. | 20185837 |
| Inflammation, Cavernous Sinus Thrombophlebitis | Altered Intercellular Communication | Clival inflammation with cavernous sinus thrombophlebitis and orbital subperiosteal abscess--case report. | 20185888 |
| Inflammation, Cavernous Sinus Thrombophlebitis, Infection, Abducens Nerve Diseases | Altered Intercellular Communication | A 64-year-old woman presented with a very rare case of three infectious lesions, cavernous sinus thrombophlebitis, clival inflammation, and orbital subperiosteal abscess (SPA), manifesting as abducens palsy. | 20185888 |
| Inflammation | Altered Intercellular Communication | The clival lesion was approached by an endonasal transsphenoidal route and diagnosed as inflammation. | 20185888 |
| Hypophysitis, CTCAE, Communicable Diseases, Granulomatous inflammation, Inflammatory, Granulomatosis with polyangiitis | Altered Intercellular Communication | An inflammatory sellar mass is very rare but includes a variety of noninfectious causes including lymphocytic hypophysitis, granulomatous inflammation and Wegener's granulomatosis. | 20186358 |
| Inflammation | Altered Intercellular Communication | One possible explanation relates to systemic inflammation, which is associated with these adverse health outcomes. | 20186494 |
| Inflammatory Bowel Diseases, Inflammation, Malnutrition, Anemia | Altered Intercellular Communication | Decreases in GPx activity corresponded with IBD activity, anemia, inflammation, and malnutrition. | 20186929 |
| Inflammation, Ulcerative Colitis | Altered Intercellular Communication | In UC, catalase activity corresponded indirectly with UC endoscopic activity and inflammation and directly with hemoglobin. | 20186929 |
| Inflammation, Anemia | Altered Intercellular Communication | SOD1, GPx1, and CAT activities are differently affected by the disease type, activity, anemia, inflammation, oxidative stress, and treatment. | 20186929 |
| Inflammation, Fibrosis Assessment, Mirizzi Syndrome, Gallbladder, Hypertension, CTCAE | Altered Intercellular Communication | When there is excess inflammation, fibrosis and portal hypertension around gall bladder or in presence of Mirizzi syndrome, bile ducts and hepatic artery may be possibly damaged during dissection of Calot triangle. | 20187468 |
| vascular inflammations, Atherosclerosis | Altered Intercellular Communication | Specific chemokines contribute to vascular inflammation and may be useful biomarkers to detect atherosclerosis. | 20187767 |
| Communicable Diseases, Inflammation | Altered Intercellular Communication | Seven miRNAs related to inflammation or infection were included in the present study. | 20188071 |
| Inflammation | Altered Intercellular Communication | Adiponectin is associated with inflammation and oxidative stress. | 20188385 |
| Inflammation, Metabolic Problems | Altered Intercellular Communication | Unequivocal evidence has emerged linking inflammation to the risk of metabolic problems. | 20189773 |
| Inflammation, Schizophrenia | Altered Intercellular Communication | Previous research also has suggested a relationship between inflammation and schizophrenia. | 20189773 |
| Inflammation, Psychiatric, Metabolic Syndrome X, Schizophrenia | Altered Intercellular Communication | The present study examined whether white blood cell count (WBC), a marker of systemic inflammation, is associated with metabolic syndrome and psychiatric symptoms in non-diabetic patients with schizophrenia. | 20189773 |
| Inflammation, Chronic Kidney Diseases | Altered Intercellular Communication | Inflammation and oxidative stress (OS) are cardiovascular risk factors in patients with chronic kidney disease. | 20190028 |
| HD Term Type, Inflammation | Altered Intercellular Communication | The OSND thus provides a comprehensive scoring system with significant associations with prospective hospitalization and mortality in chronic HD patients as well as measures of nutrition and inflammation. | 20190238 |
| Inflammation, Malnutrition, Diabetes Mellitus | Altered Intercellular Communication | After adjustment for additional parameters of inflammation and malnutrition as well as diabetes, the linear component was more significant in women (P = 0.0018) than in men (P = 0.023). | 20190241 |
| Inflammation, Chronic Kidney Diseases | Altered Intercellular Communication | The circulating soluble TRAIL is a negative marker for inflammation inversely associated with the mortality risk in chronic kidney disease patients. | 20190248 |
| Inflammation, Chronic Kidney Diseases | Altered Intercellular Communication | Circulating sTRAIL is a negative marker for inflammation and is inversely associated with the mortality risk in CKD patients. | 20190248 |
| Inflammation, Heart failure | Altered Intercellular Communication | Marked increase in the LV expression of LOX-1 in failing hearts may contribute to increased serum levels, and might be involved in chronic inflammation during the development of heart failure. | 20190428 |
| Diffuse alveolar hemorrhage | Altered Intercellular Communication | The description of bronchoalveolar lavage fluid findings showed an alveolar hemorrhage and neutrophilic inflammation. | 20190477 |
| Inflammation, Fever, CTCAE, Dry cough | Altered Intercellular Communication | The patient presented intermittent 40 masculineC fever evolving over 40 days, dry cough and painless bilateral cervical adenomegaly, showing no signs of inflammation. | 20191206 |
| Inflammation, Spondylitis | Altered Intercellular Communication | Systematic assessment of inflammation by magnetic resonance imaging in the posterior elements of the spine in ankylosing spondylitis. | 20191485 |
| Inflammation | Altered Intercellular Communication | Inflammation was scored dichotomously (present/absent) in each posterior structure. | 20191485 |
| Inflammation, Rheumatoid Arthritis | Altered Intercellular Communication | Mutuality's prospective beneficial effects on inflammation in female patients with rheumatoid arthritis. | 20191496 |
| Inflammation | Altered Intercellular Communication | Hypothesizing that mutuality has a beneficial impact on inflammation, we tested potentially causal relations of couple mutuality with erythrocyte sedimentation rate (ESR) in prospective data. | 20191496 |
| Refractory anemias, Inflammation | Altered Intercellular Communication | Patients with RA reporting more mutuality had less inflammation at subsequent time points, but inflammation had no effect on subsequent reports of mutuality. | 20191496 |
| Inflammation, Periodontitis, Diabetes Mellitus | Altered Intercellular Communication | Although worldwide evidence tends to prove that diabetes adversely affects periodontal health, there are insufficient clues indicating whether periodontitis may aggravate metabolic control and systemic inflammation. | 20192862 |
| Inflammation, Diabetes Mellitus | Altered Intercellular Communication | Salivary MMP-8 and OPG concentrations were elevated regardless of periodontal inflammation in patients with diabetes. | 20192865 |
| Inflammation, Fecal Incontinence, Anal pain | Altered Intercellular Communication | Two patients experienced mild anal incontinence when followed-up to 6 months; 2 patients suffered mild anal pain during defecation due to slight anastomotic inflammation 2 and 4 months after the operation, respectively. | 20193398 |
| Autoimmune Diseases, Inflammation, TYMS wt Allele, Gilles de la Tourette syndrome | Altered Intercellular Communication | Post-infectious autoimmunity has been implicated in pathogenesis of Tourette's syndrome (TS) but no evidence of inflammation in central nervous system has been reported yet. | 20193755 |
| Inflammation | Altered Intercellular Communication | Multiple markers of inflammation and weight status: cross-sectional analyses throughout childhood. | 20194272 |
| Inflammation, Blood Vessel | Altered Intercellular Communication | Elevated inflammatory markers in very young obese children are particularly concerning, because inflammation may cause long-term, cumulative vascular damage. | 20194272 |
| Inflammation, Fibrosis Assessment | Altered Intercellular Communication | Among investigated molecules, only MMP2 was independently related to inflammation and fibrosis according to grading (P=0.036) and staging (P=0.032) score. | 20195229 |
| Inflammation, Fibrosis Assessment | Altered Intercellular Communication | In addition MMP2 is related to inflammation and fibrosis as assessed by liver biopsy and laboratory features. | 20195229 |
| Amyotrophic Lateral Sclerosis, Inflammation | Altered Intercellular Communication | Caloric restriction shortens lifespan through an increase in lipid peroxidation, inflammation and apoptosis in the G93A mouse, an animal model of ALS. | 20195368 |
| Inflammation | Altered Intercellular Communication | We conclude that CR increases lipid peroxidation, inflammation and apoptosis, while decreasing mitochondrial bioenergetic efficiency, protein oxidation and stress response in G93A mice. | 20195368 |
| Gastrointestinal inflammation | Altered Intercellular Communication | Recent evidence suggests a crucial role of the endocannabinoid system, including the cannabinoid 1 receptor (CNR1), in intestinal inflammation. | 20195480 |
| Inflammation, Giant Cell Arteritis | Altered Intercellular Communication | Giant cell arteritis is characterized primarily by inflammation in certain large and medium-sized arteries. | 20197597 |
| Inflammation, Hemorrhage, Edema, Pulmonary Hypertension | Altered Intercellular Communication | Furthermore, Hif2a heterozygosity resulted in partial protection against vascular remodeling, hemorrhage, and edema, but not inflammation, in VhlR/R lungs, suggesting a selective role for HIF-2alpha in the pulmonary pathology and thereby providing insight into the mechanisms underlying pulmonary hypertension. | 20197624 |
| Coronary Artery Disease, Diabetes Mellitus, Non-Insulin-Dependent, Metabolic Syndrome X, Cardiovascular system | Altered Intercellular Communication | Therefore, type 2 diabetes may further increase the risk of coronary artery disease in the metabolic syndrome subjects through cardiovascular inflammation. | 20197633 |
| Inflammation | Altered Intercellular Communication | Therefore, we proposed that the dissection and the stenosis are directly induced by the inflammation of THS. | 20198499 |
| ARCN1 gene, Inflammation, Chronic Obstructive Airway Disease, Lung diseases | Altered Intercellular Communication | The integrated project COSYCONET, as part of the competence network ASCONET funded by the BMBF, has the aim to investigate the relationship between the pulmonary disorder, comorbidities and systemic inflammation in patients with chronic obstructive pulmonary disease (COPD) by adopting cross-sectional as well as longitudinal analyses. | 20198540 |
| Inflammation, Atheroma, Diabetes Mellitus, Non-Insulin-Dependent | Altered Intercellular Communication | Local non-esterified fatty acids correlate with inflammation in atheroma plaques of patients with type 2 diabetes. | 20200316 |
| Inflammation, Dental Plaque, Atherosclerosis, diabetic | Altered Intercellular Communication | Atherosclerosis is prevalent in diabetic patients, but there is little information on the localization of nonesterified fatty acids (NEFAs) within the plaque and their relationship with inflammation. | 20200316 |
| Diabetes with coma (disorder), Inflammation | Altered Intercellular Communication | We sought to characterize the NEFA composition and location in human diabetic atheroma plaques by metabolomic analysis and imaging and to address their relationship with inflammation activity. | 20200316 |
| Inflammation | Altered Intercellular Communication | We hypothesize that NEFA may be produced locally and contribute to local inflammation. | 20200316 |
| Inflammation, Adenoma of large intestine | Altered Intercellular Communication | Antioxidant micronutrients and biomarkers of oxidative stress and inflammation in colorectal adenoma patients: results from a randomized, controlled clinical trial. | 20200432 |
| Inflammation, Diverticular Diseases | Altered Intercellular Communication | Therefore the chronic inflammation and local disturbance of epithelium regeneration were established in diverticular disease. | 20201300 |
| Colitis | Altered Intercellular Communication | The severity of duodenal and colonic inflammation was determined by endoscopic and histologic scores. | 20201621 |
| Inflammation, Glaucoma, CTCAE | Altered Intercellular Communication | The histopathological findings were consistent with glaucoma and chronic inflammation. | 20202555 |
| Inflammation, Carotid Stenosis | Altered Intercellular Communication | Mycophenolate mofetil attenuates plaque inflammation in patients with symptomatic carotid artery stenosis. | 20202636 |
| Inflammation, Neoplasm Metastasis, Neoplasms, Vascular Invasion Assessment, Liver Cirrhosis | Altered Intercellular Communication | Compared with seronegative-HBsAg ICC patients, seropositive-HBsAg ICC patients were younger, more frequently male and had a higher proportion of abnormal aminotransferase and serum alpha-fetoprotein (AFP) level, histological inflammation and cirrhosis, right-lobe focus, poor tumour differentiation, tumour encapsulation and microvascular invasion; had a lower proportion of abnormal serum carbohydrate antigen 19-9 (CA19-9) level and lymphatic metastasis. | 20202823 |
| Communicable Diseases, Inflammation | Altered Intercellular Communication | The origin of this protein remodeling (involving the physical or functional absence of CFTR, infection, inflammation, or high adrenergic tone) deserves further investigation. | 20203292 |
| Inflammation, Heart failure | Altered Intercellular Communication | However, recent investigations strongly suggest that increased adiponectin production in patients with heart failure is a part of compensatory mechanisms against oxidative stress and inflammation. | 20204504 |
| Fracture, Osteopenia | Altered Intercellular Communication | Our study suggests progressive hormonal changes that may contribute to severe bone loss during the year following hip fracture. | 20204599 |
| Inflammation, Restenosis, Atherosclerosis | Altered Intercellular Communication | Atherosclerosis and restenosis are largely ruled by inflammation. | 20206356 |
| Inflammation | Altered Intercellular Communication | At surgery, inflammation remained in the middle ear, and edematous pale mucosal tissue was noted around the stapes and ossicular chain. | 20206453 |
| Inflammation, Granulation finding, Necrosis | Altered Intercellular Communication | Histopathologic examination showed inflammation and granulation tissue, but no caseating necrosis or acid-fast bacilli. | 20206453 |
| Inflammation, Prostate carcinoma | Altered Intercellular Communication | Since CRP is a marker of inflammation, this finding suggests that inflammation may play an important role in the natural history of advanced prostate cancer. | 20207556 |
| Peripheral ulcerative keratitis, Corneal Stroma, Inflammation | Altered Intercellular Communication | Peripheral ulcerative keratitis (PUK) is a disorder consisting of a crescent-shaped destructive inflammation of the perilimbal corneal stroma. | 20209701 |
| Hemorrhage, Tissue Adhesions | Altered Intercellular Communication | A VA was defined as the accidental bleeding during dissection, depending on the surgeon and/or inflammatory conditions, adhesions, and so on. | 20210667 |
| Chronic inflammation, Sarcolemma, skeletal muscle tissue regeneration, Doctor of Dental Medicine, Muscular Dystrophy, Duchenne, Disease | Altered Intercellular Communication | Duchenne muscular dystrophy (DMD), a lethal disorder characterized by dystrophin absence, courses with chronic inflammation, sarcolemmal damage, and skeletal muscle degeneration. | 20210854 |
| Inflammation, Doctor of Dental Medicine | Altered Intercellular Communication | Among the multiple pathogenic mechanisms proposed for DMD, oxidative stress and inflammation are directly involved in the dystrophic process. | 20210854 |
| ARCN1 gene, Inflammation | Altered Intercellular Communication | Local inflammation occurs before systemic inflammation in patients with COPD. | 20210891 |
| ARCN1 gene, Inflammation | Altered Intercellular Communication | COPD is associated not only with an abnormal inflammatory response in the lung but also with systemic inflammation, including systemic oxidative stress, activation of circulating inflammatory cells and increased circulating levels of inflammatory cytokines. | 20210891 |
| ARCN1 gene, Inflammation | Altered Intercellular Communication | Understanding the nature and course of systemic inflammation in COPD is important given the potential for anti-inflammatory therapy. | 20210891 |
| ARCN1 gene, Inflammation | Altered Intercellular Communication | This study explored whether local and systemic inflammation occur concurrently in patients with COPD. | 20210891 |
| ARCN1 gene, Inflammation | Altered Intercellular Communication | Systemic inflammation may be present in patients with severe or very severe COPD. | 20210891 |
| Inflammation, Rheumatoid Arthritis | Altered Intercellular Communication | Circulating surfactant protein -D is low and correlates negatively with systemic inflammation in early, untreated rheumatoid arthritis. | 20211020 |
| Inflammation | Altered Intercellular Communication | Anti-microbial and anti-inflammatory properties have been attributed to multimeric SP-D variants, while trimeric subunits per se have been suggested to enhance inflammation. | 20211020 |
| Inflammation | Altered Intercellular Communication | The exclusive presence of trimeric SP-D in affected joints may contribute to the maintenance of joint inflammation. | 20211020 |
| Metabolic Syndrome X, Cardiovascular Diseases, Presenile dementia, Diabetes Mellitus, Inflammatory disorder, Malignant Neoplasms, Arthritis | Altered Intercellular Communication | Thus, the significance of our findings is that the zingerone treatment may provide some preventive measure against chronic inflammatory conditions that underlie many age-related inflammatory diseases, such as metabolic syndrome, cardiovascular disease, dementia, arthritis, diabetes, osteoprosis, and cancers. | 20211236 |
| Inflammation, Peripheral motor neuropathy | Altered Intercellular Communication | The favorable response to treatment with IV immunoglobulins and the presence of IgM antibodies to the glycolipid GM1 are indications that inflammation underlies multifocal motor neuropathy (MMN) pathogenesis. | 20211906 |
| Anemia, Critical Illness, Intradermal Route of Drug Administration | Altered Intercellular Communication | Inflammation-induced anemia is frequent among critically ill patients and can be aggravated by true iron deficiency (ID) resulting from blood losses. | 20213069 |
| Inflammation, Intradermal Route of Drug Administration | Altered Intercellular Communication | The serum hepcidin level controls the availability of iron for erythropoiesis, and its determination offers new perspectives for the diagnosis of ID in the presence of inflammation. | 20213069 |
| Inflammation, Intradermal Route of Drug Administration | Altered Intercellular Communication | Hepcidin levels may be suppressed by ID even in case of inflammation. | 20213069 |
| Pain Distress Question, Inflammation | Altered Intercellular Communication | The relationship of Modic change to pain and inflammation remains to be unclear. | 20213295 |
| Inflammation | Altered Intercellular Communication | A 47-year-old man presented with bilateral ERD accompanied by anterior and posterior segment inflammation. | 20213612 |
| Inflammation, Urolithiasis, Chronic pyelonephritis, Hyperuricemia | Altered Intercellular Communication | It is shown that urisan contributes to intensification of renal filtration function, to reduction of hyperuricemia and urine pH, intensification of uric acid excretion, continuation of inflammation remission, attenuation of proteinurea in urolithiasis patients with exacerbation of chronic pyelonephritis. | 20213910 |
| Granulomatous inflammation, Albinism, Fibrosis Assessment, Nystagmus | Altered Intercellular Communication | He was born of a consanguineous marriage, had occulo-cutaneous albinism, nystagmus, decreased visual acuity, refractory errors, pulmonary fibrosis and granulomatous inflammation of the colon. | 20214008 |
| Whole-Body Irradiation, Traumatic, physiopathological | Altered Intercellular Communication | Hormonal dysfunction is a known consequence of moderate and severe traumatic brain injury (TBI). | 20214417 |
| Inflammation, Blood Glucose | Altered Intercellular Communication | Lipoprotein concentrations, glycemia, and inflammation parameters were determined. | 20215451 |
| Fibrous, Inflammation, Pleural plaque, Cleft ala nasi | Altered Intercellular Communication | Histologically, lesions were subdivided into 3 types: (1) "plaque-like" consisting of dense fibrous tissue with clefts without significant inflammation identical to a pleural plaque (5 cases); (2) "inflammatory sclerotic" with dense fibrous tissue containing lymphocytes (diffusely or aggregates or germinal centers), plasma cells, and an increased capillary network (6 cases); and (3) "myofibroblastic" consisting of reactive looking tissue-culture-like spindle cells with numerous capillaries and sparse chronic inflammation (2 cases). | 20216379 |
| Coronary angiography, Inflammation | Altered Intercellular Communication | Total homocysteine in patients with angiographic coronary artery disease correlates with inflammation markers. | 20216983 |
| Psychological Distress, Inflammation, Cardiovascular Diseases | Altered Intercellular Communication | Although a substantial body of research points to a link between psychological distress and inflammatory responses in middle-aged and older adults, particularly those with cardiovascular disease, the relationship between inflammation and distress in young, healthy individuals has not been established. | 20219150 |
| Symptoms, Inflammation | Altered Intercellular Communication | In this observational study, parenteral corticosteroids were associated with a statistically significant reduction in symptoms, but no statistically significant reduction in US-detected synovial inflammation. | 20219784 |
| Inflammation | Altered Intercellular Communication | The latter finding may, however, reflect the relatively low levels of synovial inflammation detected ultrasonagraphically in hand joints. | 20219784 |
| Bronchial Hyperreactivity | Altered Intercellular Communication | Using adoptive transfer of Unc119-knockdown CD4 T cells, we show a critical role for Unc119 in the development of eosinophilic inflammation of airways, mucus production, and bronchial hyperreactivity in a mouse model. | 20220094 |
| Communicable Diseases, Inflammation, Cerebral Palsy | Altered Intercellular Communication | In utero exposure to infection or inflammation is a strong and independent predictor of cerebral palsy. | 20220110 |
| Autoimmune Diseases, Idiopathic Inflammatory Myopathies, Inflammation, Proximal muscle weakness | Altered Intercellular Communication | The idiopathic inflammatory myopathies are systemic autoimmune diseases characterized by chronic inflammation, resulting in the progressive weakness of the proximal muscles. | 20221841 |
| Inflammation, Primary malignant neoplasm, Hypogonadism | Altered Intercellular Communication | Hypogonadism has been linked with systemic inflammation and opioid use in males with advanced cancer. | 20221887 |
| Inflammation, Hypogonadism, Pancreatic carcinoma | Altered Intercellular Communication | In males with pancreatic cancer, systemic inflammation and opioid use are associated with hypogonadism. | 20221887 |
| Inflammation, Chronic disease | Altered Intercellular Communication | It is implicated in the development of a variety of chronic disease states and is associated with increased levels of inflammation and oxidative stress. | 20222968 |
| Inflammation, Weight decreased, Chronic disease | Altered Intercellular Communication | Our data suggest that the meal replacement diet plan evaluated was an effective strategy for producing robust initial weight loss and for achieving improvements in a number of health-related parameters during weight maintenance, including inflammation and oxidative stress, two key factors more recently shown to underlie our most common chronic diseases. | 20222968 |
| Rheumatoid Arthritis, Spondylitis, Reactive systemic amyloidosis | Altered Intercellular Communication | Secondary amyloidosis of the bladder is of the AA type, which is more common in females and mainly secondary to rheumatoid arthritis, but also to ankylosing spondylitis and long-standing chronic inflammatory conditions. | 20223142 |
| Inflammation | Altered Intercellular Communication | The objective was to evaluate inflammation in echolucent carotid artery plaques. | 20223427 |
| Inflammation, Dental Plaque | Altered Intercellular Communication | Our results substantiate previous findings of an association between plaque FDG uptake and inflammation. | 20223427 |
| Inflammation | Altered Intercellular Communication | Echolucent plaques exhibit a wide range of inflammatory activity, whereas echorich plaques show little inflammation. | 20223427 |
| Inflammation | Altered Intercellular Communication | It has been previously demonstrated that systemic inflammation is associated with PAD and its clinical outcomes. | 20223619 |
| Inflammation | Altered Intercellular Communication | Improving the systemic milieu of insulin resistance and inflammation in these high-risk patients may lead to reduced morbidity and mortality. | 20223619 |
| Inflammation, Amyloidosis | Altered Intercellular Communication | Treatment with colchicine reduces inflammation and the risk of developing amyloidosis. | 20224617 |
| Ischemia, Gastrointestinal inflammation | Altered Intercellular Communication | The octn1 ( -/- ) mice exhibited greater susceptibility to intestinal inflammation under the ischemia and reperfusion model. | 20224991 |
| Degenerative polyarthritis, Inflammation, Obesity | Altered Intercellular Communication | Obesity, as a primary risk factor for osteoarthritis (OA), has been shown to alter joint loading, but may also result in metabolic changes characterized by chronic, low-level inflammation due to increased circulating levels of adipose-derived cytokines, or "adipokines." | 20225314 |
| Granulomatous inflammation | Altered Intercellular Communication | Granulomatous inflammation was present on follow-up biopsy specimens 4 weeks later. | 20227579 |
| Inflammation, Swelling | Altered Intercellular Communication | No more gingival inflammation or swelling was observed. | 20228992 |
| Inflammation | Altered Intercellular Communication | Reverse correlation was found with transferrin (r = -0.323, p < 0.0001), albumin (r = -0.251, p = 0.003), and S-Fe (r = -0.205, p = 0.02), parameters known to decrease during inflammation. | 20229122 |
| Inflammation | Altered Intercellular Communication | Inflammation increased levels of NT-proBNP more than BNP, resulting in an increased NT-proBNP/BNP ratio. | 20229122 |
| Inflammation, Neoplasms | Altered Intercellular Communication | The specificity in patients with the endoscopic findings described as 'negative', 'inflammation', 'scar tissue', 'flat lesion', 'suspicious for tumour', and 'exophytic tumour' was 89.8%, 89.9%, 85.0%, 77.1%, 63.2% and 48.6%, respectively (P < 0.001). | 20230393 |
| Dysplasia, Stomach Carcinoma, Infection caused by Helicobacter pylori, Stomatitis, Intestinal metaplasia | Altered Intercellular Communication | This paper shows analysis of the association of the 802C>T polymorphism of the NOD2/CARD15 gene with the occurrence of the chronic inflammation of the gastric mucosa associated with the Helicobacter pylori infections, development of intestinal metaplasia and dysplasia and, in the result of this, gastric cancer. | 20230816 |
| Inflammation, Atherosclerosis | Altered Intercellular Communication | Our findings further support a role for inflammation in the accelerated form of atherosclerosis in IRD patients, and suggest that certain inflammatory pathways, such as the enhanced endothelial cell activation and the RANK ligand/RANK/OPG system, may be of particular importance. | 20231178 |
| Refractory anemias, Rheumatoid Arthritis, Autoimmune Diseases, Inflammation | Altered Intercellular Communication | Rheumatoid arthritis (RA) is a systemic autoimmune disease characterized by chronic inflammation of the joints, which may lead to structural damage of the cartilage and bone. | 20231205 |
| Airway structure, Asthma, Bronchoconstriction | Altered Intercellular Communication | The cysteinyl leukotrienes cause bronchoconstriction, increased mucus production and airway inflammation, three major features of asthma. | 20232571 |
| Rheumatoid Arthritis, destruction joint, Inflammation | Altered Intercellular Communication | Biomarkers in early rheumatoid arthritis: longitudinal associations with inflammation and joint destruction measured by magnetic resonance imaging and conventional radiographs. | 20233753 |
| Synovitis, Inflammation, Edema of bone marrow | Altered Intercellular Communication | Consistent associations, both with MRI inflammation (synovitis and bone marrow oedema) and DAS28 were found for sYKL-40 and sMMP-3 in addition to C-reactive protein at baseline and in longitudinal analyses. | 20233753 |
| destruction joint, Arthritis, C-telopeptide | Altered Intercellular Communication | Levels of sCTX-I and uCTX-II were significant predictors of progressive joint destruction, whereas sMMP-3 and sYKL-40 were merely markers of joint inflammation. | 20233753 |
| Inflammation, Fever, CTCAE | Altered Intercellular Communication | In early July of the following year, he was re-admitted to our hospital because of continuous high fever, despite no any inflammation. | 20235483 |
| Airway structure, ARCN1 gene, Chronic Obstructive Airway Disease | Altered Intercellular Communication | It has been reported that small airway inflammation is closely associated with the severity of airflow limitation in COPD (chronic obstructive pulmonary disease). | 20236091 |
| Inflammation, Lung diseases | Altered Intercellular Communication | Mechanical ventilation with high tidal volume induces inflammation in patients without lung disease. | 20236550 |
| Lung Injury, Pneumonitis | Altered Intercellular Communication | The use of lower tidal volumes may limit pulmonary inflammation in mechanically ventilated patients even without lung injury. | 20236550 |
| Inflammation | Altered Intercellular Communication | Elderly individuals with a strong innate inflammatory system, or ongoing systemic inflammation (or both), might be most susceptible to these outcomes. | 20236772 |
| Inflammation, Damage | Altered Intercellular Communication | MSUS was performed in all patients in both hands and wrists, evaluating the presence of inflammation within joints and periarticular tissues, and the existence of permanent joint damage. | 20236956 |
| Inflammation, Neoplasms | Altered Intercellular Communication | (18)F-FLT PET/CT may have an advantage over (18)F-FDG PET/CT in differentiating inflammation from tumor. | 20237030 |
| Inflammation, conjunctiva | Altered Intercellular Communication | IL1B expression was elevated in the presence of either conjunctival bacterial infection (P = 0.011) or inflammation (P = 0.002). | 20237245 |
| Inflammation, Chlamydia Infections | Altered Intercellular Communication | TNF expression was greater in the Mandinka ethnic group (P < 0.0001), and it was increased when clinical inflammation was associated with nonchlamydial bacterial infection (P = 0.012). | 20237245 |
| Bacterial Infections, Conjunctivitis | Altered Intercellular Communication | MMP-9 expression increased when conjunctival inflammation was associated with bacterial infection (P = 0.007). | 20237245 |
| Inflammation | Altered Intercellular Communication | Peritumoral connective tissue was generally unremarkable, but chronic inflammation was present in five cases. | 20237984 |
| ARCN1 gene, Inflammation, Chronic Obstructive Airway Disease, Alveolar | Altered Intercellular Communication | Inflammation is an important constituent of the pathology of chronic obstructive pulmonary disease (COPD), leading to alveolar destruction and airway remodelling. | 20298300 |
| Communicable Diseases, Inflammation | Altered Intercellular Communication | It is characterised by pathological dilatation of the bronchi thought to result from infection and inflammation. | 20298369 |
| Inflammation, Bronchiolitis, Pneumonia | Altered Intercellular Communication | Minor findings included bronchiolitis, organizing pneumonia and peribronchial inflammation. | 20298381 |
| allergic inflammation, Allergy - Charge Type Reason | Altered Intercellular Communication | Seasonal allergy is an interesting model to study the pathophysiological mechanisms involved in allergic inflammation. | 20298416 |
| Birch Pollen IgE Measurement, Inflammation, Asthma, Rhinitis | Altered Intercellular Communication | Bronchial allergen challenge with inhalation of birch pollen gives a similar inflammatory response in the airway but less systemic inflammation than seasonal exposure in birch pollen allergic patients with asthma and rhinitis. | 20298416 |
| Airway structure | Altered Intercellular Communication | Despite active airway inflammation, indicating need for treatment symptoms may be poorly perceived and influence on quality of life. | 20298418 |
| Inflammation | Altered Intercellular Communication | Open surgical repair of these lesions can be challenging due to the elevated venous pressure and surrounding inflammation. | 20299180 |
| Inflammation, Obesity | Altered Intercellular Communication | It has been observed that restrictive pulmonary function is associated with obesity and C-reactive protein (CRP), an indicator for systemic inflammation. | 20299196 |
| Obesity | Altered Intercellular Communication | We evaluated body composition and CRP as a categorical variable (non-obesity, percentage body fat 75 percentile; low-inflammation, CRP 75 percentile) and constructed 4 groups, which were non-overlapping (reference, inflammatory, obese, obese and inflammatory). | 20299196 |
| Inflammation | Altered Intercellular Communication | In summary, the coexistence of high fat accumulation and systemic subclinical inflammation is associated with restrictive pulmonary function. | 20299196 |
| Trauma, Nervous System | Altered Intercellular Communication | Neurotransmitter and Krebs cycle intermediate depletion in this model represent novel findings toward uncovering the mechanism of neuronal injury. | 20299259 |
| Berylliosis, Pneumonitis, cannabidiol | Altered Intercellular Communication | Chronic beryllium disease (CBD) is a CD4(+) T cell-mediated disorder characterized by persistent lung inflammation. | 20299529 |
| Tumor necrosis, Chronic Obstructive Airway Disease, Inflammation | Altered Intercellular Communication | Tumor necrosis factor-{alpha} rs361525 polymorphism is associated with increased local production and downstream inflammation in chronic obstructive pulmonary disease. | 20299531 |
| Inflammation | Altered Intercellular Communication | Their lung secretions contained more IL-8 and myeloperoxidase, consistent with downstream inflammation. | 20299531 |
| Airway structure, ARCN1 gene | Altered Intercellular Communication | Inhaled corticosteroids (ICS) have proved disappointing at reducing airway inflammation in COPD. | 20299628 |
| Airway structure, ARCN1 gene | Altered Intercellular Communication | Combination therapy with an inhaled corticosteroid and low-dose theophylline may attenuate airway inflammation in patients with COPD. | 20299628 |
| Cataract, Inflammatory abnormality of the eye, Dry Eye Syndromes | Altered Intercellular Communication | The addition of HP-Guar to regular treatment after cataract surgery reduces ocular surface inflammation and dry eye signs and symptoms. | 20300126 |
| Hepatic inflammation | Altered Intercellular Communication | In older adults (age > or = 48 years), daily fructose consumption was associated with increased hepatic inflammation (P < 0.05) and hepatocyte ballooning (P = 0.05). | 20301112 |
| Inflammation, Fibrosis Assessment | Altered Intercellular Communication | Severity of inflammation and fibrosis were not significantly different between case and control groups (P = 0.69), and between smokers and nonsmokers with PANDO (P = 0.15). | 20302403 |
| melanoma, Inflammation | Altered Intercellular Communication | Our findings, although preliminary, support the notion that the differential biology of melanoma at the extremes of age is driven, in part, by deregulation of microRNA expression and by fine tuning of miRs that are already known to regulate cell cycle, inflammation, Epithelial-Mesenchymal Transition (EMT)/stroma and more specifically genes known to be altered in melanoma. | 20302635 |
| Autoimmune Diseases, Inflammation, Immunity | Altered Intercellular Communication | CD4(+)CD25(+) regulatory T (Treg) cells and Th17 cells, subsets of T-helper cells, play important roles in peripheral immunity and their imbalance leads to the development of tissue inflammation and autoimmune diseases. | 20302843 |
| Inflammation | Altered Intercellular Communication | Angiotensin-converting enzyme (ACE) plays an important role in the physiological control of blood pressure and inflammation. | 20303010 |
| Inflammation, Giant Cell Arteritis, Takayasu Arteritis | Altered Intercellular Communication | (1,2) Histopathology usually reveals granulomatous inflammation affecting arterioles and small arteries of the parenchyma and/or leptomeninges, similar to that seen in Takayasu's or giant cell arteritis. | 20303761 |
| Vasculitis, Primary angiitis of the central nervous system, Idiopathic Inflammatory Myopathies, Vasculitis, CTCAE | Altered Intercellular Communication | Primary angiitis of the central nervous system (PACNS), also called primary CNS vasculitis, is an idiopathic inflammatory condition affecting only intracranial and spinal cord vessels, particularly medium-sized and smaller arteries and arterioles. | 20303761 |
| Communicable Diseases, Inflammation | Altered Intercellular Communication | Inflammation is an essential immune response that enables survival during infection or injury and maintains tissue homeostasis under a variety of noxious conditions. | 20303867 |
| Inflammation, Malignant neoplasm of ovary | Altered Intercellular Communication | Ovarian carcinomas are associated with increased inflammation which is based upon an up-regulation of inducible cyclooxygenase-2 (COX-2). | 20304053 |
| Temporal - Regional site descriptor, Pleurisy | Altered Intercellular Communication | The decrease observed from postoperative day 1 and thereafter suggests the action of the immunosuppression agents and a temporal reduction in pleural inflammation. | 20304185 |
| Rheumatoid Arthritis, Acute and chronic inflammation | Altered Intercellular Communication | Synoviocyte-derived angiopoietin-like protein 2 contributes to synovial chronic inflammation in rheumatoid arthritis. | 20304962 |
| Inflammation | Altered Intercellular Communication | Several proinflammatory cytokines derived from both infiltrating inflammatory cells and activated resident cells within the RA joint play a fundamental role in the processes that cause inflammation. | 20304962 |
| Refractory anemias, Inflammation, destruction joint | Altered Intercellular Communication | Therefore, an effort has been made to identify other key regulators of inflammation in articular structures to develop new therapies to suppress synovial inflammation and joint destruction in RA. | 20304962 |
| Inflammation, Obesity | Altered Intercellular Communication | Adipose tissue-derived angiopoietin-like protein 2 (Angptl2) activates an inflammatory cascade in endothelial cells and induces chemotaxis of monocytes/macrophages in obesity, resulting in initiation and propagation of inflammation within adipose tissues and obesity-related metabolic diseases. | 20304962 |
| Autoimmune Thyroid Disease Pathway, Colorectal Carcinoma, Malignant Neoplasms | Altered Intercellular Communication | Increased incidence of mostly autoimmune thyroid disease has been associated with breast and other malignancies, and thyroid hormone levels might also be associated with risk of colorectal cancer (CRC). | 20305129 |
| Inflammation, Rheumatoid Arthritis, destruction joint | Altered Intercellular Communication | Cytokines such as TNF-alpha and IL-6, play key roles in driving the inflammation and synovial cell proliferation that characterize rheumatoid arthritis and joint destruction. | 20306675 |
| Fibrosis Assessment, Alport Syndrome, Nephritis | Altered Intercellular Communication | The present study evaluates the role of Discoidin Domain Receptor 1 (DDR1) in cell-matrix interaction involved in pathogenesis of Alport syndrome including renal inflammation and fibrosis. | 20307660 |
| Renal fibrosis, Inflammation, Hereditary | Altered Intercellular Communication | Loss of DDR1-expression in the kidney delayed renal fibrosis and inflammation in hereditary type IV collagen disease. | 20307660 |
| Disturbance, Inflammation | Altered Intercellular Communication | In addition, markers of immune disturbance, inflammation and disease activity using the European League Against Rheumatism SS Disease Activity Index were analysed in patients. | 20308122 |
| Osteomyelitis, Inflammation, Fracture, Degenerative polyarthritis | Altered Intercellular Communication | Of 15 lesions initially classified as osteomyelitis, four were diagnosed as osteoarthritis, four as fracture, and one as inflammation of the soft tissue only. | 20308478 |
| Inflammation, "Alzheimers Disease", Data types - Address | Altered Intercellular Communication | Inflammation is believed to play a role in Alzheimer's disease (AD). | 20308780 |
| Neoplasms, Ulcer | Altered Intercellular Communication | The most common causes are inflammations, ulcers, neoplasms and angiodysplasias. | 20309807 |
| Inflammation, Primary malignant neoplasm, Chronic disease, Cardiovascular Diseases | Altered Intercellular Communication | Oxidative stress and inflammation have been linked to many chronic diseases including cancer and cardiovascular diseases. | 20332256 |
| Infection by Trichuris trichiura, Inflammation | Altered Intercellular Communication | Among the patients with T. trichiura infection, colonoscopy showed several erosions in 2 patients (8.3%) and non-specific inflammation of the affected segment of the colon in 3 patients (12.5%). | 20333290 |
| physiopathological | Altered Intercellular Communication | Since ICUAP has been associated with female gender in some studies, we hypothesized that hormonal dysfunction might contribute to ICUAP. | 20333354 |
| Inflammation, Colorectal Carcinoma, Adenoma of large intestine | Altered Intercellular Communication | Chronic inflammation, which is suspected to play a role in the development of colorectal cancer (CRC), has rarely been studied in colorectal adenoma. | 20333461 |
| Inflammation | Altered Intercellular Communication | Although oxidative damage and inflammation have been theorized to affect RDW, the relationships of antioxidants and inflammation with RDW have not been well characterized. | 20334961 |
| Corneal ectasia | Altered Intercellular Communication | Pregnancy could prompt hormonal changes, which in turn could affect the biomechanical stability of the cornea, leading to corneal ectasia. | 20335804 |
| Inflammatory abnormality of the eye, Re-Epithelialization | Altered Intercellular Communication | Weeks after instituting systemic immunosuppressive medications, including corticosteroids and cyclophosphamide, the ocular inflammation gradually resolved with corneal re-epithelialization and severe stromal neovascularization. | 20335808 |
| Inflammation, Necrosis | Altered Intercellular Communication | The pathogenesis of surgically induced scleral necrosis not associated with autoimmune conditions may be the result of the products of inflammation and lytic enzymes released by the surrounding conjunctival tissue initiating the scleral melting process. | 20335810 |
| Inflammation, Injury of bile duct | Altered Intercellular Communication | This technique is recommended as an attractive solution to prevent bile duct injury, particularly when severe inflammation is associated to extrahepatic anatomic variants of the biliary tree. | 20336321 |
| Pain Distress Question, Sore to touch, Appendicitis, CTCAE, Inflammation | Altered Intercellular Communication | We defined equivocal appendicitis as a right lower quadrant pain with tenderness and an apppendiceal diameter of 6 to 9 mm without appendicolith or severe adjacent inflammation as radiological findings. | 20336903 |
| Inflammation | Altered Intercellular Communication | Serum metalloproteinase leukolysin (MMP-25/MT-6): a potential metabolic marker for atopy-associated inflammation. | 20337648 |
| Chronic Obstructive Airway Disease | Altered Intercellular Communication | Leukolysin is a novel matrix metalloproteinase (MMP-25/MT-6) released mainly by granulocytic cells, primarily neutrophils, which are implicated in chronic airways inflammation. | 20337648 |
| ARCN1 gene, Chronic Obstructive Airway Disease, Asthma | Altered Intercellular Communication | Among individuals with history of chronic airways inflammation (asthma and COPD) serum leukolysin may be a metabolic marker associated with chronic atopy-associated respiratory inflammation. | 20337648 |
| Inflammation | Altered Intercellular Communication | Myeloid-related protein (MRP8/14) and its subunits are biomarkers of inflammation. | 20337885 |
| Bronchiolitis, Wheezing, Neutrophilia (finding), Asthma, Inflammatory disease of mucous membrane | Altered Intercellular Communication | The mechanism by which an early, severe case of bronchiolitis can result in the development of recurrent childhood wheeze or asthma is unclear; however, mucosal inflammation and pulmonary neutrophilia are believed to play a significant role. | 20337964 |
| Communicable Diseases, Inflammation | Altered Intercellular Communication | This case emphasizes how important it is for patients after a median sternotomy to receive adequate analgesic and physiotherapeutic support in order to avoid chronic inflammation and infection of the lungs. | 20338366 |
| Cryoglobulinemic vasculitis, Inflammation, Hepatitis C, Neuropathy | Altered Intercellular Communication | In cryoglobulinemic vasculitis with hepatitis C, the severity of the neuropathy depends on the nature of the cellular inflammation and the size of the vessel involvement. | 20338607 |
| Inflammation, Saint Lucia | Altered Intercellular Communication | The inflammation was diagnosed in 72.5% of OC and 41.5% of LC patients. | 20339988 |
| Inflammation, Colorectal Carcinoma | Altered Intercellular Communication | Increased risk of colorectal cancer among patients with biliary tract inflammation: a 5-year follow-up study. | 20340129 |
| Inflammation, Colorectal Carcinoma | Altered Intercellular Communication | The purpose of the study was to investigate the risk of colorectal cancer among patients with biliary tract inflammation (BTI) compared to non-BTI patients during a 5-year follow-up period. | 20340129 |
| Colorectal Carcinoma, Cholangitis | Altered Intercellular Communication | We also found that the adjusted hazard ratio for colorectal cancer for those with bile duct inflammation was 3.30 times (95% CI = 1.87-5.84) as high as for those without BTI within the 5-year follow-up period. | 20340129 |
| Cholecystitis, Colorectal Carcinoma | Altered Intercellular Communication | However, no increased hazard of colorectal cancer was observed for patients with gallbladder inflammation. | 20340129 |
| Inflammation, Sore to touch | Altered Intercellular Communication | Noted on presentation were bite marks on the right middle toe with minimal inflammation and tenderness. | 20345298 |
| Inflammation, Neoplasms, Gout | Altered Intercellular Communication | The tumor was ultimately found to be secondary to gouty inflammation of the pes anserine bursa, a previously unrecognized manifestation of acute gout. | 20345364 |
| Acute Kidney Injury, CTCAE, Inflammation, Malnutrition, Crush syndrome | Altered Intercellular Communication | Malnutrition and inflammation in acute kidney injury due to earthquake-related crush syndrome. | 20346168 |
| Acute Kidney Injury, CTCAE, Inflammation, Malnutrition, Kidney Failure, Acute | Altered Intercellular Communication | Malnutrition and inflammation are common and serious complications in patients with acute kidney injury (AKI). | 20346168 |
| Inflammation, Malnutrition, Kidney Failure, Acute | Altered Intercellular Communication | This study describes the clinical characteristics of malnutrition and inflammation in patients with AKI and CS due to the Wenchuan earthquake. | 20346168 |
| Inflammation, Malnutrition | Altered Intercellular Communication | Malnutrition and inflammation was common in patients with earthquake-related CS and had a negative impact on the prognosis of these subjects. | 20346168 |
| Crush syndrome, Inflammation, Malnutrition | Altered Intercellular Communication | The results of this study indicate that the use of RRT, intensive nutritional supplementation and transfusion alleviated the degree of malnutrition and inflammation in hemodialysis patients with crush syndrome. | 20346168 |
| Inflammation, Hydrarthrosis, Knee joint, Gout | Altered Intercellular Communication | Fifty-one (25.5%) knee joints were found clinically involved, while at least one US finding indicative of joint inflammation was obtained in 73 (36.5%) knee joints.The most frequent US finding indicative of knee joint inflammation was joint effusion, detected in 21 (35%) out of 60 knees and in 52 (37%) out of 140 knees, in gout and CPPD disease, respectively. | 20346230 |
| Inflammation | Altered Intercellular Communication | Resistin was associated with laboratory markers of inflammation. | 20346233 |
| Refractory anemias, Inflammation | Altered Intercellular Communication | Positive correlation between levels of visfatin and resistin may suggest that visfatin plays a role in inflammation in RA. | 20346233 |
| Inflammation, Rheumatoid Arthritis, Metabolic Syndrome X | Altered Intercellular Communication | Visfatin is not associated with inflammation or metabolic syndrome in patients with severe rheumatoid arthritis undergoing anti-TNF-alpha therapy. | 20346239 |
| Refractory anemias, Inflammation, Atherosclerosis | Altered Intercellular Communication | Chronic systemic inflammation is of major importance in the development of atherosclerosis in RA. | 20346239 |
| Inflammation | Altered Intercellular Communication | However, it remains unclear whether such abnormalities result from systemic inflammation or from abnormalities at stem cell level. | 20346245 |
| Refractory anemias, Inflammation | Altered Intercellular Communication | The results suggest that the enhanced expression of FKBP5 in BM CD34+ cells might be an intrinsic abnormality of RA BM CD34+ cells, whereas the enhanced expression of AREG and CXCR4 in BM mononuclear cells might be secondary to systemic inflammation. | 20346245 |
| Inflammation, Chronic heart failure | Altered Intercellular Communication | Relation of left ventricular ejection fraction and functional capacity with metabolism and inflammation in chronic heart failure with reduced ejection fraction (from the MIMICA Study). | 20346316 |
| Inflammation, Heart failure | Altered Intercellular Communication | Catabolism and inflammation play a role in the physiopathology of heart failure with reduced ejection fraction and are more pronounced in the advanced stages of the disease. | 20346316 |
| Pain Distress Question, Cystitis | Altered Intercellular Communication | Cannabinoid receptor agonists have been shown to modulate urinary bladder contractility and reduce pain after bladder inflammation; their clinical efficacy on lower urinary tract symptoms was demonstrated in the Cannabinoids in Multiple Sclerosis study. | 20346490 |
| Cessation of life, Diabetes Mellitus | Altered Intercellular Communication | Markers of malnutrition-inflammation (albumin, hemoglobin, and white blood cell values) or the presence of diabetes did not influence the relation between glycemic control and death (all P for interaction > 0.2). | 20346561 |
| Inflammation, Heart failure | Altered Intercellular Communication | Neurohormonal activation and inflammation characterizes heart failure, relates to outcome, and is a therapeutic target. | 20346637 |
| Inflammation, atherosclerotic, diabetic | Altered Intercellular Communication | Enhanced tyrosine nitration of prostacyclin synthase is associated with increased inflammation in atherosclerotic carotid arteries from type 2 diabetic patients. | 20348234 |
| Atherosclerosis, Diabetes Mellitus, vascular inflammations, Diabetes Mellitus, Non-Insulin-Dependent, atherosclerotic | Altered Intercellular Communication | These data demonstrate that diabetes preferentially increases PGIS nitration that is associated with excessive vascular inflammation in atherosclerotic carotid arteries from patients with type 2 diabetes, suggesting a possible role of tyrosine nitration of PGIS in the development of atherosclerosis in patients with diabetes. | 20348234 |
| Inflammation | Altered Intercellular Communication | Human intestinal ischemia-reperfusion-induced inflammation characterized: experiences from a new translational model. | 20348235 |
| Inflammation | Altered Intercellular Communication | Although intestinal IR-induced inflammation has been studied extensively in animal models, human intestinal IR induced inflammatory responses remain to be characterized. | 20348235 |
| Inflammation | Altered Intercellular Communication | Markers of inflammation and oxidative stress in peritoneal dialysis: a comparison between high and low peritoneal transporters. | 20349414 |
| Inflammation | Altered Intercellular Communication | It has been hypothesized that this might be a result of a state of chronic inflammation and increased oxidative stress. | 20349414 |
| Uremia, Inflammation, Malnutrition, Immune System Diseases | Altered Intercellular Communication | Neutrophils in uremia maintain chronic inflammation, which contributes to malnutrition and immunity disorders. | 20349422 |
| COLLAGENOSIS, FAMILIAL REACTIVE PERFORATING, polychondritis, Inflammation, Collagen Diseases | Altered Intercellular Communication | Relapsing polychondritis (RPC) is a rare rheumatic disease characterized by recurrent inflammation of cartilaginous structures, with airway involvement a major cause of morbidity and mortality. | 20350245 |
| Inflammatory Bowel Diseases, Crohn Disease, Gastrointestinal inflammation, Ulcerative Colitis | Altered Intercellular Communication | Deficiency in 1alpha,25-dihydroxyvitamin D(3) (1,25D(3)) has been suggested as an important environmental factor for immuno-mediated disorders including inflammatory bowel diseases (IBD), comprising Crohn's disease and ulcerative colitis, both characterized by chronic intestinal inflammation. | 20350569 |
| Inflammation | Altered Intercellular Communication | Whether inflammation, an outcome predictor in dialysis patients, plays a role is unknown. | 20350963 |
| Inflammation, Uremic pruritus | Altered Intercellular Communication | Inflammation may bridge uremic pruritus to high mortality, and elevated hs-CRP predicts a worse outcome in this population. | 20350963 |
| Inflammation, Vascular Diseases | Altered Intercellular Communication | C-reactive protein is a marker of inflammation and vascular disease. | 20350977 |
| Inflammation | Altered Intercellular Communication | These data suggest that low-grade inflammation as assessed by high-sensitivity C-reactive protein is associated with cerebral microstructural disintegration that predominantly affects frontal pathways and corresponding executive function. | 20350977 |
| Inflammation, Fibrosis Assessment | Altered Intercellular Communication | The lesions formed masses with an infiltrative pattern and all had 3 key histologic features: fibrosis, chronic inflammation, and fat necrosis-without a known etiology. | 20351487 |
| Inflammation, Hyperemia | Altered Intercellular Communication | There were no significant differences in endoscopic hyperemia and histological inflammation among the groups (P>0.05). | 20352149 |
| Cerebrovascular Disorders, Inflammation, Thrombosis | Altered Intercellular Communication | Inflammation and thrombosis, two processes influencing each other, are involved in the pathogenesis of cerebrovascular disease. | 20352160 |
| Inflammation, Cerebral Ischemia | Altered Intercellular Communication | These results indicate that monocytes activated by inflammation rather than platelets might be the candidates to initiate platelet-monocyte rosetting during the pathogenesis of atherothrombotic cerebral ischaemia and that haemostasis might be activated secondarily by the first occurring inflammation. | 20352160 |
| Inflammation | Altered Intercellular Communication | Surgical removal and histopathology showed evidence of severe chronic sterile inflammation and no malignant cell. | 20352220 |
| Lymphocyte count increased, Lymphocytic Choriomeningitis, Esophagitis | Altered Intercellular Communication | Lymphocytic esophagitis (LE), a new entity characterized by peripapillary lymphocytosis, questions the role lymphocytes play in esophageal inflammation. | 20353445 |
| Refractory anemias, Pain Distress Question, Inflammation, Fatigue | Altered Intercellular Communication | Fatigue in RA was related to pain and functioning, not inflammation, as disease-related factors and to several psychosocial factors including coping and cognitions concerning fatigue. | 20353956 |
| Hay fever | Altered Intercellular Communication | Alpha-melanocyte-stimulating hormone plays an important role in the onset of pollinosis in a pollen allergy mouse model. | 20357480 |
| Airway structure, Asthma | Altered Intercellular Communication | Exhaled breath temperature (EBT) has been suggested as a non-invasive surrogate marker of airway inflammation in asthma. | 20357487 |
| Airway structure, Exacerbation of asthma | Altered Intercellular Communication | Changes in airway inflammation during virus-induced asthma exacerbations are reflected in EBT changes. | 20357487 |
| Airway structure | Altered Intercellular Communication | These preliminary data suggest a possible role of EBT measurements in the assessment of airway inflammation in children with virus-induced asthma. | 20357487 |
| Colitis, Non-necrotizing granulomatous inflammation, Diverticular Diseases, Deficiency of butyryl-CoA dehydrogenase, Inflammatory disorder, Diverticular disease of colon | Altered Intercellular Communication | Segmental colitis associated with diverticular disease (SCAD) is a colonic inflammatory disorder with localized non-granulomatous inflammation at sigmoid colon, and associated with colonic diverticulosis. | 20357530 |
| nervous system disorder, Inflammation, Primary malignant neoplasm, Chronic disease | Altered Intercellular Communication | Oxidative stress is involved in the pathogenesis of many chronic disorders including cancer, inflammation, and neurologic diseases. | 20357718 |
| Inflammation, Primary malignant neoplasm, Osteomyelitis, Crohn Disease, Chronic gastritis | Altered Intercellular Communication | Cancer can arise in areas of chronic inflammation such as osteomyelitis with a draining sinus, Crohn's disease, or chronic gastritis. | 20359562 |
| Weight Gain, Inflammation | Altered Intercellular Communication | This suggests that inflammation plays a key role in the process of weight gain, especially after smoking cessation. | 20360759 |
| Inflammation, Fibrosis Assessment, Fatty degeneration | Altered Intercellular Communication | Fibrosis, lobular inflammation, ballooning and steatosis were evaluated (Brunt system). | 20361076 |
| Inflammation, Fibrosis Assessment, Fatty degeneration | Altered Intercellular Communication | In the univariate analysis, LS was correlated with fibrosis (r=0.661; p<0.0001), steatosis (r=0.435, p<0.0001), ballooning (r=0.385; p=0.001) and lobular inflammation (r=0.364; p=0.002). | 20361076 |
| Inflammation, Fatty degeneration, Liver Stiffness | Altered Intercellular Communication | Steatosis, ballooning and inflammation do not influence liver stiffness. | 20361076 |
| Inflammation, Ulceration, CTCAE, Stenosis | Altered Intercellular Communication | One case in particular is, to our knowledge, the first report of the natural history of this clinical entity, initially presenting with the acute picture of inflammation and ulceration with subsequent progression to the more chronic development of diaphragm-like fibrous strictures. | 20361083 |
| Inflammation | Altered Intercellular Communication | An intriguing finding was the absence of chronic inflammation in partial atrophy foci as well as in areas of mergence between these lesions. | 20361207 |
| Inflammation, Atrophic | Altered Intercellular Communication | Inflammation was present only in isolated complete focal atrophy foci. | 20361207 |
| Tissue damage, Inflammation, Atrophic, Ischemia | Altered Intercellular Communication | The question of whether the inflammation produces tissue damage and prostatic atrophy or whether some other insults like ischemia induces the tissue damage and atrophy directly, with inflammation occurring secondarily, is still unsettled. | 20361207 |
| Inflammation | Altered Intercellular Communication | The absence of severe toxoplasmic foetopathy, the very exaggerated and atypical placental inflammation and the immune restoration context led to the diagnosis of placental IRIS associated with Toxoplasma gondii reactivation. | 20361998 |
| Inflammation, Aortic valve disorder | Altered Intercellular Communication | Prior studies suggest that the causes of calcific aortic valve (AV) disease involve chronic inflammation, lipoprotein levels, and calcium metabolism, all of which may differ among race-ethnic groups. | 20362732 |
| Inflammation | Altered Intercellular Communication | Low fluidic parameters led to a lower increase in CCT 1 day and 7 days postoperatively, decreased anterior segment inflammation at 1 day, and yielded clear corneas. | 20362850 |
| Inflammation | Altered Intercellular Communication | In asthma hyperresponsiveness to adenosine (AMP) is more closely related to inflammation than to methacholine (MCh). | 20363117 |
| Inflammation, Overweight | Altered Intercellular Communication | Overweight asthmatic women have more pronounced systemic inflammation, but are less responsive to MCh. | 20363117 |
| Airway structure, Overweight | Altered Intercellular Communication | Our findings suggest that overweight asthmatic women do not feature increased airway inflammation, but do represent a distinct phenotype as compared to normal weight patients. | 20363117 |
| Pneumonitis | Altered Intercellular Communication | Loss of negative feedback control of nuclear factor-kappaB2 activity in lymphocytes leads to fatal lung inflammation. | 20363924 |
| Alveolar damage, Fibrosis Assessment, Pneumonitis | Altered Intercellular Communication | Here we show that mice deficient in p100 but with constitutive expression of p52 in lymphocytes developed fatal lung inflammation characterized by diffuse alveolar damage with marked peribronchial fibrosis. | 20363924 |
| Pneumonitis | Altered Intercellular Communication | In contrast, their littermates with only p100 deficiency or constitutive expression of p52 in lymphocytes developed mild lung inflammation with perivascular lymphocyte infiltration and had a normal life span. | 20363924 |
| Pneumonitis | Altered Intercellular Communication | The fatal lung inflammation is associated with high-level induction of interferon-gamma and its inducible inflammatory chemokines, suggesting the involvement of a T-helper-1 immune response. | 20363924 |
| Inflammation, Congestive heart failure | Altered Intercellular Communication | Our aim was to define the distribution of monocyte subsets in a cohort of congestive heart failure (CHF) patients, to verify whether increased severity of CHF is linked to the expansion of specific monocyte subsets, and finally to investigate the relationship between monocyte subset relative frequencies, laboratory parameters of inflammation, and monocyte ACE expression. | 20364047 |
| Inflammation, Electrocardiogram: myocardial infarction (finding), atherosclerotic | Altered Intercellular Communication | Vascular endothelial growth factor (VEGF) is a potent angiogenic growth factor that has been shown to play a significant role in neovascularization during inflammation in atherosclerotic plaques, formation of collateral vessels to an area of ischemic myocardium and neovascularization at the edges of a myocardial infarction during its repair. | 20364398 |
| Airway structure, Allergic, Asthma, Bronchial Hyperreactivity | Altered Intercellular Communication | Although much is known about the fact that IgE-mediated allergic inflammatory response contributes to airway inflammation, bronchial hyperresponsiveness, and asthma severity, little is known about the degree of IgE response in allergic asthmatics during treatment. | 20364560 |
| Inflammation, Atherosclerosis | Altered Intercellular Communication | Malnutrition-inflammation score associated with atherosclerosis, inflammation and short-term outcome in hemodialysis patients. | 20364569 |
| Inflammation, Malnutrition | Altered Intercellular Communication | Malnutrition-Inflammation Score (MIS) has been proposed as a new quantitative system for assessment of malnutrition and inflammation, which are common important risk factors for increased morbidity and mortality in maintenance hemodialysis (MHD) patients. | 20364569 |
| Inflammation, Saint Lucia | Altered Intercellular Communication | Inflammation was diagnosed in 55.6% of OC patients and 36.0% of LC patients. | 20367813 |
| Inflammation | Altered Intercellular Communication | Diagnosis of inflammation, presence of co-morbidities and BDD each had a significant impact on LOS and TC. | 20367813 |
| Hyperuricemia | Altered Intercellular Communication | In T2DM males, hyperuricaemia is associated with raised neurohormones together with better beta-cell indices. | 20368210 |
| Inflammation, Diabetes Mellitus, Non-Insulin-Dependent | Altered Intercellular Communication | Hypovitaminosis D in Chinese type 2 diabetes: lack of impact on clinical metabolic status and biomarkers of cellular inflammation. | 20368211 |
| Inflammation, Atherosclerosis | Altered Intercellular Communication | The chemokine monocyte chemoattractant protein-1 (MCP-1) is implicated in chronic inflammation, insulin resistance and atherosclerosis. | 20368224 |
| Inflammation | Altered Intercellular Communication | Regular exercise may improve systemic markers of chronic inflammation, but direct evidence and dose-response information is lacking. | 20368384 |
| Inflammation, Pancreatitis, Failure, Diabetes Mellitus, Non-Insulin-Dependent | Altered Intercellular Communication | One of the proposed mechanisms of beta cell failure is local inflammation, but the presence of pancreatic islet inflammation in type 2 diabetes and the mechanisms involved remain under debate. | 20369226 |
| Inflammation, Diabetes Mellitus, Non-Insulin-Dependent | Altered Intercellular Communication | Saturated-fatty-acid-induced NF-kappaB activation and endoplasmic reticulum stress may contribute to IL-1beta production and mild islet inflammation in type 2 diabetes. | 20369226 |
| Acromegaly, Endocrine System Diseases | Altered Intercellular Communication | Acromegaly is a chronic endocrinopathy characterized by hypersecretion of growth hormone (GH) and consequently of insulin-like growth factor-1 (IGF-1). | 20369240 |
| Inflammation, Hyperplasia, Hypertrophy | Altered Intercellular Communication | The pancreas displayed inflammation foci, hypertrophy and hyperplasia of the islets of Langerhans. | 20369585 |
| Dyspnea, Inflammation, Chronic Obstructive Airway Disease | Altered Intercellular Communication | [The role of altered respiratory mechanics and systemic inflammation in the development of dyspnea in patients with chronic obstructive pulmonary disease]. | 20369611 |
| Inflammatory abnormality of the eye | Altered Intercellular Communication | Ocular inflammation resolved with a course of doxycyline and oral steroids. | 20370334 |
| HD Term Type, Inflammation | Altered Intercellular Communication | Chronic inflammation and oxidative stress are prevalent in hemodialysis (HD) patients. | 20370442 |
| Inflammation | Altered Intercellular Communication | Pioglitazone can decrease urinary albumin and MCP-1 excretion in type 2 diabetics, which may partly contribute to its reno-protection by inhibiting the inflammation reaction in vivo. | 20371128 |
| Inflammation, Fibrosis Assessment | Altered Intercellular Communication | The inflammation grade and fibrosis stage were assessed according to Ishak. | 20371429 |
| Inflammation, Necrotizing fasciitis, Necrosis | Altered Intercellular Communication | Necrotizing fasciitis (NF) is a rare, life-threatening soft-tissue infection, characterized by rapidly spreading inflammation, with secondary necrosis of the fascia and surrounding tissues. | 20371436 |
| Inflammation, Heart failure | Altered Intercellular Communication | Glucocorticoid receptor gene, low-grade inflammation, and heart failure: the Heart and Soul study. | 20371666 |
| Inflammation | Altered Intercellular Communication | The pathological report indicated chronic inflammation with heavy plasma cell infiltration on the specimen. | 20372941 |
| Communicable Diseases, Peptic Ulcer, Inflammatory disease of mucous membrane | Altered Intercellular Communication | Infection with the partial cagPAI strains was less likely to be associated with peptic ulcer and chronic gastric mucosal inflammation than infection with strains possessing intact cagPAI. | 20372956 |
| Inflammation, Urolithiasis | Altered Intercellular Communication | Further diagnoses were BPH (30%), inflammation (10%), urolithiasis (7%), and"further conditions" (16%). | 20373094 |
| Inflammation | Altered Intercellular Communication | Markers of platelet mediated inflammation showed increasing (CD40 ligand) and decreasing (P-selectin) levels after PCI. | 20373128 |
| Inflammation, Dental Plaque, Rupture, Atherosclerosis | Altered Intercellular Communication | Accumulating evidence suggests that inflammation as well as oxidative stress play essential roles in atherogenesis, progression of atherosclerosis, and plaque instability and rupture. | 20374186 |
| Inflammation, Diabetes Mellitus, Non-Insulin-Dependent | Altered Intercellular Communication | Obesity-related chronic inflammation is implicated in the pathogenesis of type 2 diabetes (T2D). | 20375213 |
| Inflammation, Diabetes Mellitus, Non-Insulin-Dependent, Obesity | Altered Intercellular Communication | The role of immune cells in the chronic inflammation of obesity and T2D requires further investigation. | 20375213 |
| Inflammation, Anemia | Altered Intercellular Communication | On D16, low plasma albumin increased, anemia improved, and high levels of inflammation markers declined. | 20375421 |
| Nasal inflammation | Altered Intercellular Communication | Her nasal inflammation progressed despite trials of prednisone, methotrexate, and azathioprine. | 20375822 |
| Granulomatous inflammation | Altered Intercellular Communication | A septal perforation developed and a repeat biopsy showed granulomatous inflammation. | 20375822 |
| Inflammation, Hypertension, CTCAE | Altered Intercellular Communication | Inflammation and incident-isolated systolic hypertension in older adults: the Rotterdam study. | 20375909 |
| Inflammation, Biliary calculi | Altered Intercellular Communication | Ultrasound showed gallstones without inflammation of the gallbladder. | 20375939 |
| Inflammation, Psoriasis, Dermatitis, Atopic, Dermatologic disorders, Data types - Address | Altered Intercellular Communication | Atopic dermatitis (AD) and psoriasis are common skin diseases characterized by cutaneous inflammation and disturbed epidermal differentiation. | 20376060 |
| Inflammation, Thrombus, Coronary Artery Disease, Thrombophilia | Altered Intercellular Communication | Hypercoagulability, platelet function, inflammation and coronary artery disease acuity: results of the Thrombotic RIsk Progression (TRIP) study. | 20377327 |
| Inflammation, Coronary Artery Disease, Thrombophilia | Altered Intercellular Communication | The objective of the study was to determine the relation of platelet reactivity, hypercoagulability and inflammation in various stages of coronary artery disease acuity (CAD). | 20377327 |
| Inflammation, Thrombophilia, Cardiovascular Diseases | Altered Intercellular Communication | A distinct pathophysiological state of heightened platelet function, hypercoagulability and inflammation marks the presence of unstable cardiovascular disease requiring intervention. | 20377327 |
| Inflammation, Atherosclerosis | Altered Intercellular Communication | Chronic inflammation due to antigen-specific responses is an important factor in the acceleration of atherosclerosis. | 20377769 |
| Rheumatoid Arthritis, Inflammation, Endothelial dysfunction | Altered Intercellular Communication | Long-term anti-TNF-alpha treatments reverse the endothelial dysfunction in rheumatoid arthritis: the biological coherence between synovial and endothelial inflammation. | 20378011 |
| Refractory anemias, Rheumatoid Arthritis, Inflammation, Endothelial dysfunction | Altered Intercellular Communication | Rheumatoid arthritis (RA) is associated with an excess cardiovascular morbidity and mortality, related to systemic inflammation with endothelial dysfunction (ED) and impaired flow-mediated vasodilation (FMD). | 20378011 |
| Sjogrens Syndrome", Inflammation | Altered Intercellular Communication | Is there a link between inflammation and abnormal lipoprotein profile in Sjogren's syndrome? | 20378384 |
| Sjogrens Syndrome", Inflammation, PEELING SKIN SYNDROME | Altered Intercellular Communication | To investigate the lipoprotein profile of patients with primary Sjogren's syndrome (pSS) and its association with laboratory tests, including markers of inflammation. | 20378384 |
| Inflammation, Dyslipidemias, PEELING SKIN SYNDROME | Altered Intercellular Communication | The presence of dyslipidemia in pSS was associated with increased ESR (44.05+/-28.07 versus 28.28+/-18.00, P=0.03), but not with other laboratory markers of the disease and inflammation. | 20378384 |
| vascular inflammations | Altered Intercellular Communication | Angiopoietin-1 is a vascular strengthening factor during vascular development and a protective factor for pathological vascular inflammation and leakage. | 20378606 |
| Inflammation, Cerebrovascular accident | Altered Intercellular Communication | Brain vascular leaking and inflammation are two important pathological processes of stroke; therefore, we hypothesized that variants of the microRNA-binding site in angiopoietin-1 would affect its expression and confer a risk of stroke. | 20378606 |
| Inflammation, Hypertension, CTCAE, physiopathological | Altered Intercellular Communication | Emerging evidence suggests a role for resistin in inflammation and vascular dysfunction, which may contribute to the pathogenesis of hypertension, but the association between resistin levels and incident hypertension is unknown. | 20378819 |
| Malnutrition, Dyslipidemias | Altered Intercellular Communication | Serum beta(2)-microglobulin was associated with longer duration on hemodialysis, malnutrition inflammation (lower serum albumin and higher high-sensitivity C-reactive protein) and dyslipidemia. | 20379193 |
| Xanthogranulomatous inflammation, Xanthogranulomatous cholecystitis | Altered Intercellular Communication | Macroscopic and microscopic findings revealed xanthogranulomatous inflammation, which led to a diagnosis of xanthogranulomatous pancreatitis. | 20382597 |
| Inflammation, Diabetes Mellitus | Altered Intercellular Communication | Immune system cells are important modulators of chronic inflammation in diabetes mellitus, but the role of B cells is not adequately studied. | 20383694 |
| Inflammation, Diabetes Mellitus | Altered Intercellular Communication | Altered TLR function in B cells from diabetes mellitus patients increases inflammation by two mechanisms: elevation of pro-inflammatory IL-8 and lack of anti-inflammatory/protective IL-10 production. | 20383694 |
| Granulomatous inflammation | Altered Intercellular Communication | Biopsies of oral mucosa (gingiva, buccal) exhibited in one case granulomatous inflammation, and in both cases, thick irregular clumps of tortuous, red-staining abnormal elastic fibers. | 20384464 |
| Macular Edema, Cystoid, Acute inflammation | Altered Intercellular Communication | In spite of the greater theoretical risk of increased postoperative inflammation following MSICS, there was no evidence of cystoid macular oedema, either clinically or on OCT. | 20384591 |
| Inflammation | Altered Intercellular Communication | This study reveals that HLA-DR expression is modulated differently on CD14HIGH (classical) versus CD14LOW (inflammatory) monocytes after systemic inflammation. | 20385017 |
| Overgrowth, Inflammation, Lower Urinary Tract Symptoms, Benign prostatic hypertrophy | Altered Intercellular Communication | Chronic inflammation is now considered a determinant of benign prostatic hyperplasia (BPH), promoting, together with the hormonal milieu, prostate overgrowth and lower urinary tract symptoms (LUTS). | 20386089 |
| Overgrowth, Inflammation, Lower Urinary Tract Symptoms, Benign prostatic hypertrophy | Altered Intercellular Communication | Chronic inflammation is now considered a determinant of benign prostatic hyperplasia (BPH), promoting, together with the hormonal milieu, prostate overgrowth and lower urinary tract symptoms (LUTS). | 20386089 |
| Inflammation, Hyperoxia | Altered Intercellular Communication | Herein, we determined the contribution of mechanical ventilation, hyperoxia and inflammation, individually or combined, to the cytokine/chemokine response of the neonatal lung. | 20386489 |
| Inflammation | Altered Intercellular Communication | Depending on the individual cytokine or chemokine, the combination of both oxygen and inflammation intensifies or abrogates the low VT-induced inflammatory response. | 20386489 |
| Inflammation, Hypoxia, Diabetes Mellitus, Non-Insulin-Dependent, Abnormality of mitochondrial metabolism | Altered Intercellular Communication | Because mitochondrial dysfunction, inflammation, endoplasmic-reticulum stress and hypoxia all inactivate mTORC1, our results may suggest a unifying mechanism for the pathogenesis of insulin resistance in T2D, although the underlying causes might differ. | 20386866 |
| Degenerative polyarthritis, Pain Distress Question, Inflammation | Altered Intercellular Communication | Aceclofenac, a NSAID is widely used in the treatment of pain and inflammation associated with osteoarthritis. | 20387351 |
| Inflammation, Stenosis, Traumatic injury, Hypospadias | Altered Intercellular Communication | Three of the strictures were due to trauma, one was due to inflammation, and one was due to a failed hypospadia repair. | 20387514 |
| Chronic lymphocytic inflammation, Malignant Neoplasms | Altered Intercellular Communication | Histological examination of a pleural biopsy specimen obtained by thoracoscopy showed chronic lymphocytic inflammation, but no malignancy. | 20387528 |
| Inflammation, Inflammatory edema | Altered Intercellular Communication | The paper describes a case of disseminated intestinal and cutaneous thromboangiitis (Kohlmeier-Degos' syndrome) in a 32-year-old female patient who has died from intoxication due to severely impaired permeability of the epithelial barrier mainly of the large bowel (diphtheritic inflammation of the mucosa, severe inflammatory edema of the submucous layer, and fibrinous impregnation of the serous membrane). | 20387678 |
| Inflammation, Fibrosis Assessment, Stenosis Morphology, Ulcer, Foot-and-Mouth Disease, Intestines, Small | Altered Intercellular Communication | More than three ulcerations (aphthous lesions or ulcers) or the presence of stenosis caused by inflammation or fibrosis was diagnostic of small bowel CD. | 20388061 |
| Inflammation, Carcinogenesis | Altered Intercellular Communication | It is noteworthy the potential association of common SNPs in pro-inflammatory genes with PC risk, since chronic inflammation is assumed to play a key role in prostate carcinogenesis. | 20388081 |
| Inflammation, Electrocardiogram: myocardial infarction (finding) | Altered Intercellular Communication | Inflammation and ECM (extracellular matrix) remodelling play important roles in LV (left ventricular) remodelling following acute MI (myocardial infarction). | 20388121 |
| Inflammation | Altered Intercellular Communication | PBMCs also contribute to systemic and regional inflammation and matrix remodelling in acute MI. | 20388121 |
| Vanishing bile duct syndrome, Necrosis with inflammation | Altered Intercellular Communication | The main pathological changes of CR were the vanishing bile duct syndrome and obliterative arteriopathy;and the early stage of CR were the damage of inter lobular bile duct, necrotic inflammation in central lobule, and inflammatory cells infiltration in portal area. | 20388439 |
| HD Term Type, Inflammation | Altered Intercellular Communication | Chronic inflammation in haemodialysis (HD) patients indicates a poor prognosis. | 20388631 |
| Inflammation, Cholestasis, Bile duct structure | Altered Intercellular Communication | Liver biopsy revealed portal inflammation, severe bile duct loss, and cholestasis. | 20388938 |
| Communicable Diseases, Inflammation | Altered Intercellular Communication | These findings suggest that H. pylori does not influence antioxidants bioavailability in its asymptomatic stages of infection until a factor or combination of factors triggers the inflammation cascade which may lead to increased oxidative stress and possibly reduced bioavailability of vitamins E and C. | 20389061 |
| Inflammation, Cavitation (process), Edema | Altered Intercellular Communication | MRI showed inflammation and edema in the area of the thalamus and internal capsule in the early stage, then cavitation and gliosis in the same regions in the late stage. | 20389171 |
| Inflammation, Necrosis | Altered Intercellular Communication | Biopsy specimen from the mass showed inflammation and necrotic debris. | 20389181 |
| Crohn Disease, Inflammation, Ulcerative Colitis | Altered Intercellular Communication | The purpose of this work was to determine in colon mucosa of Crohn's disease (CD) and ulcerative colitis (UC) in relapse: a) the levels of the chaperonins Hsp60 and Hsp10; b) the quantity of inflammatory cells; and c) if the levels of chaperonins parallel those of inflammation cells. | 20390473 |
| Inflammation, Ulcerative Colitis | Altered Intercellular Communication | Cells typical of inflammation were significantly more abundant in CD and UC than in NC. | 20390473 |
| Inflammation | Altered Intercellular Communication | Since chaperonins are key factors in the activation of the immune system leading to inflammation, we propose that they play a central role in the pathogenesis of the two diseases, which, consequently, ought to be studied as chaperonopathies. | 20390473 |
| Waldenstrom Macroglobulinemia, Systemic disease, Disease | Altered Intercellular Communication | IgG4-related systemic disease, a disorder recognized only recently, can cause lymphoplasmacytic inflammation in the thoracic aorta. | 20391477 |
| Kidney Failure, Chronic, Inflammation, Hemochromatosis | Altered Intercellular Communication | Biological levels are increased in end-stage renal disease and during inflammation but suppressed in hemochromatosis. | 20391595 |
| Inflammation, Biliary Tract Hemorrhage | Altered Intercellular Communication | Her Pap smear revealed inflammation with a S haematobium egg. | 20391981 |
| Bacterial Vaginosis, Inflammation, Candidiasis | Altered Intercellular Communication | Similarly, annual follow-up of Pap smears for the past 13 years showed mild inflammation with bacterial vaginitis and monilial infection. | 20391981 |
| Parkinson Disease, Neurodegenerative Disorders, palladium | Altered Intercellular Communication | Parkinson's disease (PD) is a neurodegenerative disorder caused by a disruption of dopaminergic neurotransmission in the basal ganglia. | 20392453 |
| Inflammation, Liver damage, Metabolic Syndrome X | Altered Intercellular Communication | Ferritin reflected iron stores and metabolic syndrome components, but not inflammation or liver damage. | 20392616 |
| Inflammation | Altered Intercellular Communication | Local production of cytokines within the liver may play a pivotal role in the regulation of pathophysiological processes during inflammation. | 20393789 |
| Complete atrioventricular block, Hepatitis | Altered Intercellular Communication | Liver IL-17-producing cell infiltration was positively associated with the grade of liver inflammation in CHB and positively correlated to intrahepatic IL-8 expression (r=0.801, p<0.01) or neutrophil infiltration (r=0.917, p<0.01). | 20393789 |
| Liver damage | Altered Intercellular Communication | Inappropriate, excessive, and non-specific Th17 and Th1 effector responses may be involved in the pathogenesis of HBV-associated liver inflammation and hepatocellular damage. | 20393789 |
| Granulomatous inflammation | Altered Intercellular Communication | Endoscopic sinus surgery confirmed the CT findings, allowed a biopsy taken, and the histology showed prominent caseating granulomatous inflammation. | 20394554 |
| Inflammation, Atherosclerosis | Altered Intercellular Communication | Inflammation is known to play an important role in atherosclerosis. | 20394901 |
| Inflammation | Altered Intercellular Communication | Positron emission tomography imaging with (18)F-FDG provides a measure of plaque inflammation. | 20394901 |
| Inflammatory disorder | Altered Intercellular Communication | Elevation of serum autoantibodies to alpha-enolase (ENO1) is often seen in inflammation diseases. | 20395242 |
| vascular inflammations, atherosclerotic | Altered Intercellular Communication | Imaging with (18)F-FDG PET/CT is able to reveal vascular inflammation, and several studies have shown that increased (18)F-FDG uptake in carotid artery plaques can qualify the degree of atherosclerotic inflammation. | 20395325 |
| Inflammation | Altered Intercellular Communication | A high oxHDL state may be associated with PEW estimated by GNRI and SGA, particularly concomitant with inflammation in MHD patients. | 20395357 |
| Sepsis, Inflammation | Altered Intercellular Communication | Suppressed neutrophil apoptosis, a hallmark of sepsis, perpetuates inflammation and delays resolution. | 20395555 |
| Airway structure, ARCN1 gene, Chronic Obstructive Airway Disease | Altered Intercellular Communication | Airway inflammation is a central feature of chronic obstructive pulmonary disease (COPD). | 20395558 |
| Inflammation | Altered Intercellular Communication | Selected genes involved in inflammation, oxidative stress, and proteolysis were assessed by focused gene array and real-time polymerase chain reaction. | 20395558 |
| Inflammation, septic | Altered Intercellular Communication | ADMA catabolism appears to be activated by inflammation; its increase during the advanced septic phase in surviving patients may suggest an endogenous inhibition of NO synthesis during the full-blown septic phase. | 20395894 |
| Granuloma, Inflammation | Altered Intercellular Communication | Pleural biopsy revealed 54.5% granulomatous lesion with or without caseation and another 24.2% shows chronic inflammation. | 20395911 |
| Pain Distress Question, Inflammation | Altered Intercellular Communication | Outcome measures were i) patients experience of pain and discomfort post-operatively ii) grade of inflammation post-operatively and iii) visual outcome. | 20395917 |
| Chemosis of conjunctiva, Inflammation, Corneal edema, Conjunctival congestion | Altered Intercellular Communication | Post-operative inflammation was assessed by slit lamp considering conjunctival congestion, chemosis, corneal striation, corneal oedema, cells and flare in anterior chamber. | 20395917 |
| Inflammation, Metabolic Syndrome X | Altered Intercellular Communication | Body fat distribution and inflammation among obese older adults with and without metabolic syndrome. | 20395951 |
| Adenoma, Non-Functioning Endocrine Neoplasm | Altered Intercellular Communication | Although most AIs are nonfunctioning benign adenomas, a multidisciplinary approach with biochemical and radiological evaluation is needed to characterize these lesions and identify patients who are at high risk for hormonal or malignant evolution. | 20396632 |
| Inflammation, Rheumatoid Arthritis | Altered Intercellular Communication | Effect of combination of anticytokine preparations anaferon and artrofoon on immune inflammation in rheumatoid arthritis. | 20396720 |
| Inflammation, Appendicitis, CTCAE, Gangrene | Altered Intercellular Communication | The pathology showed negative inflammation in 4 cases (9.3%), suppurative appendicitis in 29 cases (67.4%), gangrenous appendicitis in 8 cases (18.6%), and perforated appendicitis in 2 cases. | 20396909 |
| Inflammation, Pain Distress Question | Altered Intercellular Communication | Only one patient required readmission due to pericecal inflammation and pain, and another patient needed a percutaneous drainage of fluid collection. | 20396909 |
| Microalbuminuria, Rheumatoid Arthritis, Hypertension, CTCAE, Inflammation | Altered Intercellular Communication | Microalbuminuria in rheumatoid arthritis in the post penicillamine/gold era: association with hypertension, but not therapy or inflammation. | 20396921 |
| Microalbuminuria, Inflammation, Cyclophosphamide/Vincristine/Dacarbazine Regimen, Cardiovascular Diseases | Altered Intercellular Communication | Microalbuminuria (MA) has been shown to associate with inflammation and future cardiovascular disease (CVD). | 20396921 |
| Inflammation | Altered Intercellular Communication | Of the 3 patients who had not demonstrated restricted diffusion on DWI, 2 did not undergo surgery and the other was found to have only chronic inflammation at surgery. | 20397131 |
| Inflammation | Altered Intercellular Communication | The results show that the cyclosporine-induced gingival enlargement of these children is not statistically associated with their age, gender, gingival inflammation, or serum level of cyclosporine (P >0.05). | 20397903 |
| Gingival Hyperplasia, Inflammation, Dental Plaque | Altered Intercellular Communication | Children administered cyclosporine after liver transplantation show that gingival enlargement is statistically more related to the plaque index than other factors such as age, gender, gingival inflammation, or the serum level of cyclosporine, which suggests that plaque control plays an important role in eliminating gingival enlargement in children who have undergone liver transplantation. | 20397903 |
| Inflammation | Altered Intercellular Communication | A short-term evaluation of Nd:YAG laser as an adjunct to scaling and root planing in the treatment of periodontal inflammation. | 20397904 |
| Inflammation, Tegumentary leishmaniasis susceptibility, TRPV6 gene | Altered Intercellular Communication | Skin inflammation plays an important role during the healing of American tegumentary leishmaniasis (ATL), the distribution of cells in active lesions may vary according to disease outcome and parasite antigens in ATL scars have already been shown. | 20398229 |
| Inflammation, Coronary Stenosis, Pliability, Endothelial dysfunction | Altered Intercellular Communication | Endothelial dysfunction, reduction of the arterial flexibility as well as increased serum inflammation were associated with mild coronary stenosis. | 20398485 |
| Pharyngitis, Anxiety, CTCAE 3.0, Inflammatory disorder of cartilage, Dyspnea, Anti-Arrhythmia Agents, dendritic spine neck | Altered Intercellular Communication | These data led to identification of a persistent respiratory infection-related clinical syndrome, including persistent throat infection, neck spinal lesion, rib cartilage inflammation, symptoms of cardiac depression and dyspnea with or without anxiety. | 20398562 |
| ETV3 wt Allele | Altered Intercellular Communication | We measured their level and cellular origin in subjects with MetS and analyzed their associations with 1/anthropometric and biological parameters of MetS, 2/inflammation and oxidative stress markers. | 20399083 |
| Vascular Diseases, Chronic inflammation | Altered Intercellular Communication | An important non-traditional risk factor for vascular disease is chronic inflammation. | 20399263 |
| Inflammation, Kidney Failure | Altered Intercellular Communication | Subclinical inflammation might be related to cellular senescence mechanisms in leukocytes that are fostered by renal insufficiency. | 20399263 |
| Have Autoimmune or Inflammatory Condition | Altered Intercellular Communication | Decreased expression of FcgammaRIIB or non-functional FcgammaRIIB variants are associated with the development of autoimmune tissue inflammation. | 20399509 |
| Inflammation, Infected hematoma | Altered Intercellular Communication | On account of the absence of the most constant findings, the pulsation of a soft tissue mass and elevated inflammation blood parameters, we preoperatively assumed an infected haematoma. | 20400918 |
| Inflammation, Acute Coronary Syndrome, Coronary heart disease | Altered Intercellular Communication | In recent years, researchers have investigated the relationship between biological markers of inflammation and prognosis in patients who experience acute coronary syndromes; however, the association between plasma fibrinogen and coronary heart disease is still not clear. | 20401290 |
| Inflammation, Neoplasms | Altered Intercellular Communication | Further studies are needed to fully understand the changes that may affect knee mechanics after surgery and/or inflammation factors secreted by tumor cells. | 20402336 |
| Communicable Diseases, Gastrointestinal symptom, Inflammation | Altered Intercellular Communication | The relationship between infection, gastrointestinal symptoms, and systemic inflammation is poorly understood. | 20402811 |
| Stomach Diseases, Inflammation, Gastritis, Infection caused by Helicobacter pylori, Foveolar hyperplasia | Altered Intercellular Communication | H. pylori-infected patients had higher scores for acute and chronic inflammation (P < 0.001) and foveolar hyperplasia (P < 0.005) than non-infected patients, while other parameters for gastritis and gastropathy were similar between infected and non-infected patients. | 20403032 |
| Inflammation, Communicable Diseases, Traumatic injury, Leukomalacia, Periventricular, Cessation of life | Altered Intercellular Communication | Infection and inflammation leading to injury or death of pre-oligodendrocytes (preOLs) is one of the principal initiating mechanisms in the pathogenesis of preterm periventricular leukomalacia (PVL). | 20403340 |
| Inflammation, Coronary Artery Disease | Altered Intercellular Communication | The association between systemic inflammation and the estimated 10-year risk for coronary artery disease (CAD) according to the Framingham risk score is largely unknown. | 20403480 |
| Inflammation, Hyperhomocysteinemia | Altered Intercellular Communication | In conclusion, these findings indicate that low-grade systemic inflammation and hyperhomocysteinemia were present in participants with high 10-year risk for CAD. | 20403480 |
| Respiratory Distress Syndrome, Adult, Pneumonitis, Respiratory Distress Syndrome, Newborn | Altered Intercellular Communication | Acute respiratory distress syndrome (ARDS) is characterized by overwhelming lung inflammation. | 20404020 |
| Communicable Diseases, Chikungunya Fever, Inflammation | Altered Intercellular Communication | Persistent chronic inflammation and infection by Chikungunya arthritogenic alphavirus in spite of a robust host immune response. | 20404278 |
| HMGCL gene, Inflammation, hepcidin, Anemia | Altered Intercellular Communication | Elevated hepcidin levels result in iron restriction and signs of anemia of chronic inflammation, although hepcidin-independent mechanisms contribute to development of anemia in HL. | 20406921 |
| Inflammation, Infection | Altered Intercellular Communication | Inflammation and cytokine patterns produced by T lymphocytes play an important role in susceptibility to infections. | 20407285 |
| Inflammation, Organ Dysfunction Scores, Brain Death | Altered Intercellular Communication | In conclusion, the presence of inflammation and apoptosis induction may explain the rapid organ dysfunction seen after brain death. | 20407403 |
| Burn Specimen Source Codes, Hypermetabolism, Inflammation | Altered Intercellular Communication | Increased catecholamine (CA) levels after severe burn are associated with stress, inflammation, hypermetabolism, and impaired immune function. | 20407405 |
| Gait Disorders, Neurologic, Inflammation, Stanford Cancer Institute, Cervical spinal cord injury | Altered Intercellular Communication | Much of the morbidity and mortality that occurs in patients afflicted with cervical spinal cord injury (SCI) occurs early after injury due to primary neurologic dysfunction, systemic inflammation, concomitant injuries, treatments to prevent and ameliorate secondary insults, and prolonged immobilization. | 20407933 |
| Lymphoma, T-Cell, Cutaneous, Inflammation, Psoriasis, Dermatitis | Altered Intercellular Communication | Decreased T-cell Ku70 expression was not a feature of the benign dermatoses psoriasis and contact dermatitis, suggesting that loss of Ku70/80 in CTCL is not simply the result of cutaneous inflammation. | 20408834 |
| BDI - Functional Impairment, Anemia, Inflammation, Anemia, Sickle Cell | Altered Intercellular Communication | In conclusion, NT-proBNP elevation is common and is associated with markers of anaemia, inflammation and iron status and with severe functional impairment among sickle cell anaemia patients in Nigeria. | 20408845 |
| Inflammation, Meckel Diverticulum, Perforation (observation) | Altered Intercellular Communication | Emergency operation finally confirmed a 12-cm giant Meckel's diverticulum with genuine inflammation and imminent perforation. | 20409519 |
| Inflammation, Diabetes Mellitus, Non-Insulin-Dependent | Altered Intercellular Communication | Plasma concentration of visfatin is a new surrogate marker of systemic inflammation in type 2 diabetic patients. | 20409603 |
| Diabetic Nephropathy, Inflammation, diabetic | Altered Intercellular Communication | It is not clear whether plasma visfatin level is related with systemic inflammation or diabetic nephropathy in diabetic patients. | 20409603 |
| Inflammation, diabetic | Altered Intercellular Communication | These findings suggest that visfatin synthesis is activated from adipose tissue in a diabetic environment, induces NF-kappaB activation and leads to activation of pro-inflammatory cytokines and systemic inflammation. | 20409603 |
| Inflammation | Altered Intercellular Communication | Urinary hepcidin correlated positively with the 2 measured indicators of inflammation (r > or = 0.42, P < 0.01) but not with the 2 indicators of iron nutrition (r < 0.07). | 20410090 |
| Inflammation, Neoplasms, Obesity | Altered Intercellular Communication | A number of adipocytokines are increased in obesity causing low-level chronic inflammation associated with an increased risk of tumors. | 20410173 |
| Abnormal oral mucosa morphology, Superficial ulcer, Barrett Esophagus, Stenosis, Ulcer | Altered Intercellular Communication | Acid-related damage was defined as any of these findings recorded in CORI: Barrett's esophagus; esophageal inflammation (unless non-acid-related etiology); healed ulcer, duodenal, gastric or esophageal ulcer; stricture; and mucosal abnormality with erosion or ulcer. | 20411426 |
| Inflammation | Altered Intercellular Communication | Nuclear factor kB (NF-kB) essential modulator (NEMO) that is required for the activation of NF-kB plays an important role in inflammation. | 20412081 |
| Inflammation, Granuloma | Altered Intercellular Communication | The higher frequency of S. aureus colonisation could be a consequence of a recently shown mucosal barrier defect in WG and facilitate chronic inflammation and granuloma formation in the upper respiratory tract. | 20412703 |
| Inflammation, Dental Plaque | Altered Intercellular Communication | In this case it was the result of an inappropriate choice of a healing cap, thus allowing an accumulation of dental plaque and sustained chronic inflammation of the peri-implant tissue. | 20413199 |
| Inflammation, Atherosclerosis | Altered Intercellular Communication | Although inflammation is an important component of atherosclerosis, it is unknown whether inhaled corticosteroids (ICS) as anti-inflammatory drugs prevent atherosclerosis. | 20413534 |
| ARCN1 gene, Inflammation, Chronic Obstructive Airway Disease | Altered Intercellular Communication | Previous studies suggest a relationship between systemic inflammation and body composition in chronic obstructive pulmonary disease (COPD). | 20413541 |
| Plaque, Atherosclerotic | Altered Intercellular Communication | Inflammation within carotid atherosclerotic plaque: assessment with late-phase contrast-enhanced US. | 20413774 |
| Inflammation, atherosclerotic | Altered Intercellular Communication | This technique has promise as a tissue-specific marker of inflammation and a potential role in the risk stratification of atherosclerotic carotid stenosis. | 20413774 |
| Inflammation, Renal function | Altered Intercellular Communication | Further study in younger populations may clarify whether impaired kidney function leads to change in inflammation over time. | 20413990 |
| Inflammation, Chronic Kidney Diseases | Altered Intercellular Communication | Intima-media thickness is associated with inflammation and traditional cardiovascular risk factors in non-dialysis-dependent patients with chronic kidney disease. | 20413996 |
| Inflammation, Atherosclerosis | Altered Intercellular Communication | Intima-media thickness (IMT) and inflammation are early atherosclerosis markers, although data are lacking about their association in the CKD non-dialysis-dependent (CKD-NDD) population. | 20413996 |
| Eye pain, Disorder of the optic nerve, Inflammation | Altered Intercellular Communication | It is reported to emphasize that rapidly progressive severe bilateral optic neuropathy in a young patient with periocular pain need not be caused by inflammation. | 20414132 |
| Inflammation, Bronchogenic Carcinoma | Altered Intercellular Communication | In the remaining 3, biopsy revealed no bronchogenic carcinoma (3 patients with inflammation). | 20414943 |
| Communicable Diseases, Inflammation, Inflammatory disorder | Altered Intercellular Communication | 99th Dahlem conference on infection, inflammation and chronic inflammatory disorders: lifestyle changes affecting the host-environment interface. | 20415845 |
| Communicable Diseases, Inflammation, Inflammatory disorder | Altered Intercellular Communication | 99th Dahlem conference on infection, inflammation and chronic inflammatory disorders: darwinian medicine and the 'hygiene' or 'old friends' hypothesis. | 20415854 |
| Airway structure | Altered Intercellular Communication | Exhaled nitric oxide is a non-invasive marker of airway inflammation and a portable analyser, the NIOX MINO (Aerocrine AB, Solna, Sweden), is now available. | 20416092 |
| Granulomatous inflammation, Granuloma | Altered Intercellular Communication | Pathologic examination showed granulomatous inflammation in 16 patients (66.7%), including 10 patients with caseating granulomas. | 20417504 |
| Bronchial Hyperreactivity, Thickened, Smooth muscle (tissue), Airway Remodeling, Hypertrophy, Chronic eosinophilic inflammation, Hyperplasia | Altered Intercellular Communication | Chronic eosinophilic inflammation may promote bronchial hyperresponsiveness (BHR), which involves reversible reduction of airflow and airway remodelling such as a thickening of the reticular basement membrane (RBM) and hypertrophy and hyperplasia of airway smooth muscle (ASM). | 20418085 |
| Airway structure | Altered Intercellular Communication | BHR to histamine (Hist) and acetylcholine (ACh) cannot differentiate airway inflammation and remodelling. | 20418085 |
| Inflammation, Asthma | Altered Intercellular Communication | To examine the correlations between eosinophilic inflammation or airway remodelling and BHR to Hist or ACh in adults with severe asthma. | 20418085 |
| Airway structure, Asthma | Altered Intercellular Communication | In adult patients with severe asthma, BHR to ACh is related to the degree of eosinophilic airway inflammation, whereas BHR to Hist indicates airway remodeling, particularly ASM hypertrophy. | 20418085 |
| Acute Lung Injury, glycation, Inflammation, Idiopathic Pulmonary Fibrosis | Altered Intercellular Communication | Plasma was collected from patients with stable IPF, acute exacerbation of IPF, and acute lung injury for measurement of biomarkers of cellular activity/injury (receptor for advanced glycation endproducts, surfactant protein D, KL-6, von Willebrand factor), systemic inflammation (IL-6), and coagulation/fibrinolysis (protein C, thrombomodulin, plasminogen activator inhibitor-1). | 20418386 |
| Inflammation, Brain Injuries, COL4A2 wt Allele | Altered Intercellular Communication | These data suggest that inflammation occurs early and persists for several days after ICH in humans and could be involved in the progression of ICH-induced secondary brain damage. | 20420814 |
| Multiple Organ Failure, Inflammation, Communicable Diseases, Traumatic injury, Cessation of life | Altered Intercellular Communication | Death after trauma, infection, or other critical illness has been attributed to unbalanced inflammation, in which dysregulation of cytokines leads to multiple organ dysfunction and death. | 20421061 |
| Disability, Inflammation, Paresis, Functional Disability | Altered Intercellular Communication | Recent studies have suggested that inflammation may play an important role in aging and the development of disabilities, but knowledge about its importance in the development of muscle weakness and functional disabilities in very old people is limited. | 20421241 |
| Inflammation | Altered Intercellular Communication | To examine this, we found two types of responders to cantharidin-induced skin blisters in male healthy volunteers: those with immediate leukocyte accumulation and cytokine/chemokine synthesis followed by early resolution and a second group whose inflammation increased gradually over time followed by delayed resolution. | 20421472 |
| Inflammation, Carcinogenesis, Carcinoma of lung | Altered Intercellular Communication | Chronic inflammation could play a role in lung carcinogenesis, underscoring the potential for lung cancer prevention and screening. | 20421535 |
| Inflammation, Carcinoma of lung | Altered Intercellular Communication | We investigated the association of circulating high-sensitivity C-reactive protein (CRP, an inflammation biomarker) and CRP single nucleotide polymorphisms (SNPs) with prospective lung cancer risk. | 20421535 |
| Carcinogenesis, Carcinoma of lung, Pneumonitis | Altered Intercellular Communication | Elevated CRP levels are associated with subsequently increased lung cancer risk, suggesting an etiologic role for chronic pulmonary inflammation in lung carcinogenesis. | 20421535 |
| Presenile dementia, Inflammation, ETV3 wt Allele | Altered Intercellular Communication | However, since inflammation has been suggested among the MetS components, we propose IRBS as an additional feature of the metabolic-cognitive syndrome to also identify a molecular profile in patients at high risk of developing predementia or dementia syndromes. | 20421697 |
| Nonalcoholic Steatohepatitis, Inflammation, Fibrosis Assessment, Fatty degeneration, Non-alcoholic Fatty Liver Disease | Altered Intercellular Communication | The liver biopsies were evaluated and prospectively scored for pathology using 3 independent scoring systems validated for nonalcoholic steatohepatitis and nonalcoholic fatty liver disease [Brunt, NAFLD activity score (NAS) and Dixon methods], whereby numeric values were assigned to degrees of steatosis, inflammation, and fibrosis. | 20421811 |
| Inflammation | Altered Intercellular Communication | The Spearman correlation coefficient between the NAS inflammation subscore and serum B12 concentration was 0.02. | 20421811 |
| Calgranulin B, Primary malignant neoplasm, Inflammation | Altered Intercellular Communication | Calgranulin B is a small calcium-binding protein with several immunological functions mainly involved in chronic inflammation and cancer. | 20422274 |
| Inflammation, Cyclophosphamide/Vincristine/Dacarbazine Regimen, Chronic Kidney Diseases, Cardiovascular Diseases | Altered Intercellular Communication | Chronic kidney disease (CKD) is a newly recognized high-risk condition for cardiovascular disease (CVD), and previous studies reported the changes in inflammation and oxidative stress in advanced stages of CKD. | 20423474 |
| Inflammation | Altered Intercellular Communication | We compared the levels of serum biomarkers for inflammation and oxidative stress between subjects with normal and mildly reduced glomerular filtration rate (GFR). | 20423474 |
| Diffuse Axonal Injury, Inflammation, MS gene | Altered Intercellular Communication | It is well documented that disability accumulation in multiple sclerosis is correlated with axonal injury and that the extent of axonal injury is correlated with the degree of inflammation. | 20423930 |
| Inflammation, Nerve Degeneration | Altered Intercellular Communication | However, the interdependence between focal inflammation, diffuse inflammation and neurodegeneration, and their relative contribution to clinical deficits, remains ambiguous. | 20423930 |
| Inflammation, MS gene | Altered Intercellular Communication | A hypothesis might be that early focal inflammation could be the pivotal event from which all else follows, suggesting the consideration of multiple sclerosis as a two-stage disease. | 20423930 |
| Inflammation, Multiple Sclerosis | Altered Intercellular Communication | Our findings demonstrate that multiple sclerosis disability progression follows a two-stage process, with a first stage probably dependent on focal inflammation and a second stage probably independent of current focal inflammation. | 20423930 |
| Inflammation, AAVS1 gene, Vasculitis, CTCAE | Altered Intercellular Communication | Osteopontin is a pleiotropic cytokine involved in the recruitment and retention of neutrophils to sites of inflammation, which are the primary targets cells in antineutrophil cytoplasmic autoantibody-associated vasculitis (AAV). | 20424002 |
| Inflammation | Altered Intercellular Communication | This study is the first to demonstrate diabetes-specific changes in vitreous lipid autacoids including arachidonate and docosahexanoate-derived metabolites indicating an increase in inflammatory versus anti-inflammatory lipid mediators that correlated with increased levels of inflammatory and angiogenic proteins, further supporting the notion that inflammation plays a role the pathogenesis of this disease. | 20424229 |
| Inflammation | Altered Intercellular Communication | It is thus possible for PCNSBL to be histologically misinterpreted as a result of ancillary inflammation, characterized here as a profusion of T cells and macrophages. | 20425050 |
| Inflammation, HIV Infections | Altered Intercellular Communication | Inflammation is a hallmark of age-associated comorbidities, and immune activation is a hallmark of HIV disease. | 20425052 |
| Coinfection, Inflammation | Altered Intercellular Communication | Constant stimulation of the immune system by HIV or due to co-infections activates the innate and adaptive immune system, resulting in release of mediators of inflammation. | 20425052 |
| Accessory breast, Communicable Diseases, Inflammation | Altered Intercellular Communication | In case of polymastia diagnosis is simple; in case of isolated nodule, without local inflammation or infection, there are greater difficulties. | 20426920 |
| Inflammation, Cerebrovascular accident | Altered Intercellular Communication | Differences in plaque inflammation according to stroke mechanism are an understudied issue. | 20427044 |
| thromboembolic, Cerebral Ischemia | Altered Intercellular Communication | The purpose of this pilot study was to compare carotid plaque inflammation in patients with thromboembolic and hemodynamic cerebral ischemia. | 20427044 |
| Inflammation, Atherosclerosis | Altered Intercellular Communication | Chronic inflammation and oxidative stress are common risk factors for atherosclerosis. | 20427734 |
| Refractory anemias, Rheumatoid Arthritis, Periodontitis | Altered Intercellular Communication | Rheumatoid arthritis (RA) and periodontitis are common chronic inflammatory conditions and share many pathologic features. | 20429644 |
| AURKAIP1 gene, Autoimmune Pancreatitis | Altered Intercellular Communication | Autoimmune pancreatitis (AIP) is a chronic inflammatory condition characterized by IgG4-positive plasma cells. | 20429758 |
| Sepsis, Inflammation, Observation Method - Coagulation | Altered Intercellular Communication | Activation of inflammation and coagulation are closely related and mutually interdependent in sepsis. | 20429897 |
| Inflammation, Atherosclerosis | Altered Intercellular Communication | Statins reduce cardiovascular-related morbidity and mortality, but their effects on inflammation in atherosclerosis are not fully understood. | 20430391 |
| Asthma, Pneumonitis | Altered Intercellular Communication | Intranasal administration of recombinant rhinovirus proteinase 2A in mice resulted in an increase in airway hyperreactivity, lung inflammation, and IL-4 and IFN-gamma production from CD4 T cells. | 20430426 |
| Inflammation, Neoplasms | Altered Intercellular Communication | They are biomarkers of inflammation and indicators of the immune response to tumors. | 20430730 |
| Inflammation, Prostatic Neoplasms, Prostate carcinoma | Altered Intercellular Communication | Presence of xenotropic murine leukemia virus-related virus and chronic inflammation in prostate tumor suggests that inflammation plays a role in prostate cancer etiology. | 20431935 |
| Crohn Disease, Inflammation, Atherosclerosis | Altered Intercellular Communication | Patients with Crohn's disease might have accelerated atherosclerosis due to: chronic systemic inflammation, metabolic changes or prolonged steroid treatment. | 20431949 |
| Cholecystitis, Obesity | Altered Intercellular Communication | Age, obesity, previous surgery, or degree of gallbladder inflammation were not exclusion criteria. | 20432208 |
| Inflammation, Gout | Altered Intercellular Communication | Crystals were detected in only 12 samples of synovial fluids, mostly in inflammation and they were all monosodium urate (MUS) so we could diagnose gout. | 20432743 |
| Inflammation, Diarrhea | Altered Intercellular Communication | Symptoms range from mild to profuse watery diarrhoea, which may be accompanied by severe life-threatening inflammation of the intestine. | 20432784 |
| Bronchiolar disease | Altered Intercellular Communication | IgG4-positive plasma cells may play a role in the pathogenesis of bronchiolar diseases associated with allergic airway inflammation. | 20432975 |
| Inflammation, Congenital vascular anomaly, Kidney Failure | Altered Intercellular Communication | T allele frequency was significantly higher in group of vascular and congenital cause of kidney failure (Pearson X2 =6.049, P<0.05) comparing to inflammation etiology group. | 20433440 |
| Multiple polyps, Disorder of olfactory system | Altered Intercellular Communication | Olfactory disorders linked to a non-blocked area around the nasal meatus (degree 1 or 2 polyposis), together with sinonasal CT scans showing beginnings of ethmoidal inflammation, should be interpreted as incipient sinonasal polyposis. | 20434719 |
| Airway structure, Asthma | Altered Intercellular Communication | Asthmatics in remission and asthma patients with a slow FEV(1) decline had a similar extent of airway inflammation and remodeling in sputum and bronchial biopsies. | 20434897 |
| Airway structure | Altered Intercellular Communication | Asthma, even when in remission, is accompanied by airway inflammation and remodeling. | 20434897 |
| Autoimmune enteropathy, Inflammatory abnormality of the eye | Altered Intercellular Communication | The ocular surface inflammation in GO seems to be due to both the dry eye and the autoimmune orbitopathy. | 20435595 |
| Inflammation, Rheumatoid Arthritis | Altered Intercellular Communication | Acute serum amyloid A induces migration, angiogenesis, and inflammation in synovial cells in vitro and in a human rheumatoid arthritis/SCID mouse chimera model. | 20435930 |
| Inflammation | Altered Intercellular Communication | Serum amyloid A (A-SAA), an acute-phase protein with cytokine-like properties, is expressed at sites of inflammation. | 20435930 |
| Rheumatoid Arthritis, Inflammation | Altered Intercellular Communication | Uncoupling of collagen II metabolism in newly diagnosed, untreated rheumatoid arthritis is linked to inflammation and antibodies against cyclic citrullinated peptides. | 20436079 |
| Uveitis | Altered Intercellular Communication | Incidence and characteristics of acute intraocular inflammation after intravitreal injection of bevacizumab: a retrospective cohort study. | 20436545 |
| Uveitis | Altered Intercellular Communication | To determine the incidence and characteristics of acute intraocular inflammation after intravitreal bevacizumab injections from a tertiary care retinal practice. | 20436545 |
| Vitritis, Inflammation | Altered Intercellular Communication | We reviewed the records of all patients with severe anterior chamber inflammation and (or) vitritis after bevacizumab injections. | 20436545 |
| Uveitis | Altered Intercellular Communication | There were a total of 9 cases of acute intraocular inflammation for an incidence of 1.30% (95% CI: 0.69%-2.47%). | 20436545 |
| Low Vision, Glaucoma, CTCAE | Altered Intercellular Communication | The mean loss of vision was 6.1 lines of Snellen visual acuity; one patient developed inflammation-induced glaucoma which required surgical intervention. | 20436545 |
| Uveitis, Unspecified visual loss | Altered Intercellular Communication | Intravitreal injection of bevacizumab is associated with a low but significant risk of acute intraocular inflammation and may result in significant visual loss. | 20436545 |
| Clostridium difficile, Diarrhea, Gastrointestinal inflammation | Altered Intercellular Communication | Diarrhea, clostridium difficile, and intestinal inflammation in residents of a long-term care facility. | 20439046 |
| Diarrhea, Gastrointestinal inflammation, Clostridium difficile colitis | Altered Intercellular Communication | Diarrhea and the presence of C difficile in the stool are associated with intestinal inflammation, as detected by fecal lactoferrin. | 20439046 |
| Colonization, Weight decreased, Gastrointestinal inflammation | Altered Intercellular Communication | With our small numbers, we were not able to identify a specific link; however, we were able to identify a correlation between weight loss and intestinal inflammation, but, with just 2 samples, not C difficile colonization. | 20439046 |
| Inflammation, Endothelial dysfunction, Obesity | Altered Intercellular Communication | Association of obesity and biomarkers of inflammation and endothelial dysfunction in adults in Inner Mongolia, China. | 20439121 |
| Inflammation, Endothelial dysfunction | Altered Intercellular Communication | Both inflammation and endothelial dysfunction are associated with increased risk of CVD. | 20439121 |
| Inflammation, Endothelial dysfunction | Altered Intercellular Communication | We examined the association between body mass index (BMI) and waist circumference (WC) with plasma concentrations of biomarkers of inflammation and endothelial dysfunction. | 20439121 |
| Inflammation, Endothelial dysfunction | Altered Intercellular Communication | WC is a stronger predictor of inflammation while BMI is a stronger predictor for endothelial dysfunction. | 20439121 |
| Inflammation, Hypoxia | Altered Intercellular Communication | This is the first study to show a direct in vivo correlation between synovial tPO(2), inflammation and cell migration, thus it is proposed that hypoxia is a possible primary driver of inflammatory processes in the arthritic joint. | 20439288 |
| Sublingual Region, Inflammation | Altered Intercellular Communication | In 32.9% of the patients at the time of first examination the extension of inflammation into parapharyngeal, pterygomandibular spaces or neck together with mouth floor cellulitis was diagnosed. | 20440093 |
| Inflammation | Altered Intercellular Communication | Histologic and microbiologic evaluation demonstrated florid inflammation and proof of Staphylococcus aureus was found intra-operatively. | 20440468 |
| Inflammation, Burn injury | Altered Intercellular Communication | The role of leukocyte adhesion molecules in patients with burns and their relationship to other parameters of inflammation and lipid metabolism is only recently beginning to be explored. | 20441058 |
| Inflammation, Cholelithiasis | Altered Intercellular Communication | A higher incidence of acute inflammation in the cholelithiasis (22.5% vs 9.5%, p = not significant [ns]) and in the H pylori positive groups (33% vs 17.6%, p = ns) were histologically detected. | 20441060 |
| Inflammation, Helicobacter pylori, Biliary calculi, Pathogenic organism | Altered Intercellular Communication | A higher incidence (10% vs 0%), p = ns) of H pylori in gallbladders with gallstones and acute inflammation, compared to gallbladders with acute inflammation but without gallstones, was noticed Helicobacter pylori is detectable in low frequency in the mucosa of the gallbladder and it does not seem to act as a lithogenic component for cholesterol gallstone formation. | 20441060 |
| Inflammation, Cholelithiasis, Biliary calculi | Altered Intercellular Communication | Its higher incidence in gallbladders with gallstones and acute inflammation, suggests a possible accessory role in a subset of patients with cholelithiasis. | 20441060 |
| Encephalitis, Sinusitis, Inflammation, Meningitis | Altered Intercellular Communication | Eleven cases were checked with magnetic resonance imaging (MRI) and four cases showed characteristics of encephalitis or meningitis, two with images of naso sinusitis and ethmoid-mastoid inflammation. | 20441698 |
| Pancreatitis, Jejunum | Altered Intercellular Communication | Computed tomography imaging showed a jejunal hematoma and pancreatitis with peripancreatic inflammation. | 20442524 |
| Inflammation, Normocytic anemia, Lupus Erythematosus | Altered Intercellular Communication | A laboratory picture of chronic inflammation, normocytic anaemia and a finding of lupus anticoagulant/antiphospholipid antibodies were observed. | 20442651 |
| Inflammation | Altered Intercellular Communication | Furthermore, the findings also indicate that T-cell apoptosis is perhaps a host regulatory mechanism to limit inflammation, rather than a pathogen-induced immune deviation. | 20443851 |
| Inflammation, Bone necrosis | Altered Intercellular Communication | Synovial inflammation in patients with osteonecrosis of the femoral head. | 20443906 |
| Inflammation | Altered Intercellular Communication | We hypothesized that patients with ON exhibit synovial inflammation. | 20443906 |
| Inflammation | Altered Intercellular Communication | Using immunohistological techniques, we found that a large population of patients with ON had synovial inflammation. | 20443906 |
| Inflammation, Corneal Endothelial Cell Loss | Altered Intercellular Communication | Markers of inflammation, fibrinolysis, endothelial damage, and oxidative stress were measured after each treatment. | 20444914 |
| Inflammation, Corneal Endothelial Cell Loss, diabetic | Altered Intercellular Communication | Ruboxistaurin did not significantly change endothelium-dependent or endothelium-independent vasodilation or blood-based markers of inflammation, fibrinolysis, endothelial damage, and oxidative stress in either diabetic or healthy subjects. | 20444914 |
| Neurotransmitters, Neurodegeneration Due To Cerebral Folate Transport Deficiency | Altered Intercellular Communication | A lumbar puncture done to look for neurotransmitter defects or cerebral folate deficiency revealed low levels of 5-methyltetrahydrofolate (31 nmol/L; reference range, 40-150 nmol/L). | 20445197 |
| perianal lesion | Altered Intercellular Communication | Inflammation of the ileon was found in 70.5% (47% ileocolonic and ileal 23.5%), nine (53%) had perianal lesions. | 20445720 |
| Inflammation, Ulcer | Altered Intercellular Communication | The macroscopic lesions were predominant stenosis 13 (76.5%), followed by ulcers in 12 (70.6%), erosive erythematous inflammation 11 (64.7%) and thickening of folds in 10 (58.8 %), seven (41%) had fistulas. | 20445720 |
| Inflammation, Biliary calculi, Congenital Abnormality | Altered Intercellular Communication | It consists of acute distension of the gallbladder without associated congenital anomalies, biliary calculi or acute local inflammation. | 20446398 |
| Inflammation, Observation Method - Coagulation, HIV Infections | Altered Intercellular Communication | Markers of inflammation, coagulation, and renal function are elevated in adults with HIV infection. | 20446848 |
| Inflammation, HIV | Altered Intercellular Communication | Human immunodeficiency virus (HIV) replication and immune activation may increase inflammation and coagulation biomarkers. | 20446848 |
| Papillary thyroid carcinoma, Inflammation, Autoimmune Diseases | Altered Intercellular Communication | The tight relationship between papillary thyroid cancer, autoimmunity and inflammation: clinical and molecular studies. | 20447069 |
| Inflammatory abnormality of the eye | Altered Intercellular Communication | This case highlights the significance of a history of PMR in patients with ocular inflammation. | 20447103 |
| Inflammation, Heart failure | Altered Intercellular Communication | The purpose of this study was to evaluate the association between inflammation and heart failure (HF) risk in older adults. | 20447537 |
| Inflammation, Atrial Fibrillation by ECG Finding, Corneal Endothelial Cell Loss | Altered Intercellular Communication | We have evaluated if the systemic biomarkers of inflammation and endothelial damage, vascular cell adhesion molecule-1 (VCAM-1) and soluble thrombomodulin may help in identifying patients prone to development of post-operative atrial fibrillation. | 20447702 |
| Inflammation | Altered Intercellular Communication | In disease-negative women, cervical inflammation was associated with an increase in VIA positivity from 6.1% to 15.5% (P<0.001). | 20447927 |
| Inflammation, Acute Coronary Syndrome, GDC AJCC Clinical Stage Terminology | Altered Intercellular Communication | Inflammation plays a key role in acute coronary syndromes (ACS). | 20447947 |
| Inflammation, Lower Urinary Tract Symptoms | Altered Intercellular Communication | Patients with inflammation were more likely to progress clinically in terms of lower urinary tract symptoms (LUTS), acute urinary retention (AUR), or BPH-related surgery. | 20448364 |
| Hyperparathyroidism, Chronic Kidney Diseases, Hypocalcemia | Altered Intercellular Communication | Elevated serum parathyroid hormone (PTH) level together with hypocalcemia in chronic kidney disease usually suggests secondary hyperparathyroidism. | 20449656 |
| Inflammation, Juvenile rheumatoid arthritis | Altered Intercellular Communication | Expression of FLICE-inhibitory protein in synovial tissue and its association with synovial inflammation in juvenile idiopathic arthritis. | 20449949 |
| Juvenile arthritis, Inflammation, Juvenile rheumatoid arthritis | Altered Intercellular Communication | To examine the expression of FLICE-inhibitory protein (FLIP) in juvenile idiopathic arthritis (JIA) and analyze its correlation with synovial inflammation. | 20449949 |
| Inflammation | Altered Intercellular Communication | The cell types expressing FLIP were further characterized, and the correlation of FLIP expression with the degree of synovial inflammation, as well as the activity of caspase 8 was then analyzed. | 20449949 |
| Juvenile arthritis, Inflammation | Altered Intercellular Communication | Moreover, the expression of FLIP in JIA synovial tissues was positively correlated with the degree of synovial inflammation (r = 0.563, P < 0.05). | 20449949 |
| Inflammation, Dental Plaque | Altered Intercellular Communication | Conversely, less width of KM is significantly associated with more gingival inflammation, more plaque accumulation, and more gingival recession. | 20450368 |
| Airway structure, Inflammation, ARCN1 gene | Altered Intercellular Communication | Chronic inflammation, especially airway inflammation, still exists in patients with stable COPD, as suggested by the different expressions of GCR and NF-kappaB between COPD patients and normal controls. | 20450542 |
| Inflammation, Fever, CTCAE | Altered Intercellular Communication | Fever due to inflammation in acute aortic dissection: Description and proposals for diagnostic and therapeutic management. | 20450855 |
| Inflammation, Attachment (action) | Altered Intercellular Communication | Khat chewing may reduce aspects related to risk of gingival and periodontal inflammation, but it appears to be associated with attachment loss at the site of chewing. | 20451834 |
| Inflammation, Coronary Artery Disease, Ventricular Dysfunction | Altered Intercellular Communication | Neopterin, a marker of inflammation and macrophage activation, is a predictor of left ventricular dysfunction in patients with coronary artery disease. | 20451908 |
| Fibrous, Inflammation, Liver diseases | Altered Intercellular Communication | Typical aspects of normal liver architecture and liver diseases, such as nuclei, sinusoids, fibrous tissue, fatty inclusions, and bile ducts but not inflammation could be visualized at high resolution. | 20452700 |
| Inflammation, Hyperplasia, Edema | Altered Intercellular Communication | Of all analyzed lesions 88 were benign (inflammation, edema, hyperplasia etc.) | 20452899 |
| Inflammation, Candida (fungus), Barrett Esophagus, Gastroesophageal reflux disease, Deglutition Disorders, Failure (biologic function) | Altered Intercellular Communication | Reasons for diagnostic failure and delay included: delayed request for endoscopy in patients with dysphagia (49%, n=18 of 37); poor recognition of typical endoscopic appearances of EOE (16%, n=6 of 37); clinical mislabelling as gastro-oesophageal reflux disease (22%, n=8 of 37) and candida (13%, n=5 of 37); histological mislabelling as gastro-oesophageal reflux disease (19%, n=7 of 37), candida (5%, n=2 of 37), 'inflammation' (8%, n=3 of 37) and Barrett's oesophagus (3%, n=1 of 37); failed recognition or recording of maximal eosinophil concentrations within biopsies (35%, n=13 of 37). | 20453656 |
| Pneumonitis | Altered Intercellular Communication | Widespread lung inflammation and increased pulmonary vascular permeability has been noted on autopsy. | 20453703 |
| Gonorrhea | Altered Intercellular Communication | Combined hormonal contraception may be protective against Neisseria gonorrhoeae infection. | 20453722 |
| Gonorrhea, Neisseria gonorrhoeae | Altered Intercellular Communication | The role of hormonal contraception on acquisition of gonorrhea has not been well-characterized, as the transmission dynamics of Neisseria gonorrhoeae are poorly understood. | 20453722 |
| Inflammation, Edema, Cellulitis | Altered Intercellular Communication | Cellulitis, an acute, spreading pyogenic inflammation of the dermis and subcutaneous tissue, predisposed by persistent leg edema, can become problematic in patients on intraspinal opioid infusion therapy. | 20456078 |
| Inflammatory Bowel Diseases, Inflammation | Altered Intercellular Communication | Infiltrating monocytes and macrophages contribute to the initiation and perpetuation of mucosal inflammation characteristic for human inflammatory bowel disease (IBD). | 20456413 |
| Inflammation, Ischemic stroke | Altered Intercellular Communication | Inflammation and activated leucocytes are involved in the pathogenesis of acute ischaemic stroke. | 20456424 |
| Inflammation, Granulation finding | Altered Intercellular Communication | Histologically, a dermal small vessel proliferation with mixed inflammation (granulation tissue-like changes) was identified in 58% of specimens. | 20456544 |
| Inflammation | Altered Intercellular Communication | Haemodialysis patients show signs of chronic inflammation and reduced appetite, which is associated with a worse clinical status and an increased mortality risk. | 20456591 |
| Airway structure, Asthma | Altered Intercellular Communication | Exposure to particulate matter (PM) can induce airway inflammation and exacerbation of asthma. | 20456673 |
| Atherosclerosis | Altered Intercellular Communication | Atherosclerosis is an inflammatory condition where cysteinyl leukotrienes have been identified to play an important role. | 20456754 |
| Inflammation, Fibrosis Assessment, Infection | Altered Intercellular Communication | Cystic fibrosis (CF) affects the lungs causing infections and inflammation. | 20457545 |
| Inflammation, Crohn Disease | Altered Intercellular Communication | Vulvar inflammation as the only clinical manifestation of Crohn disease in an 8-year-old girl. | 20457677 |
| Granulomatous inflammation | Altered Intercellular Communication | We report here the case of an 8-year-old girl with chronic vulvar edema, which on biopsy revealed granulomatous inflammation of the vulva. | 20457677 |
| Inflammation, Bacterial Infections | Altered Intercellular Communication | Results of the biological workup were negative for general inflammation, vitamin deficiency, and bacterial and viral infections. | 20457964 |
| Inflammation, Keratopathy | Altered Intercellular Communication | There was resolution of the inflammation; however, bullous keratopathy was subsequently noted in the cornea. | 20458221 |
| Inflammatory abnormality of the eye, Corneal Perforation | Altered Intercellular Communication | Rituximab may be the elective treatment for severe anterior ocular inflammation associated with risk for corneal perforation, as a result of WG. | 20458228 |
| Inflammation, Anemia, Hematemesis | Altered Intercellular Communication | A 73-year-old man was admitted to the hospital due to severe hematemesis and collapse, severe anemia and inflammation. | 20458458 |
| Inflammation, Thickened | Altered Intercellular Communication | The puncture of a peritoneal thickening also showed inflammation. | 20458459 |
| Pancreatitis, Acute, Inflammation, Pancreatitis | Altered Intercellular Communication | Cryoaffection on pancreatic gland stump during PDR performance have resulted in lowering of early postoperative complications frequency (pancreatic fistula, parapancreatic septic inflammation and an acute pancreatitis) and of chronic pancreatitis acute phase evolvement risk in the late postoperative period. | 20458943 |
| Fibrosis Assessment, Interstitial inflammation | Altered Intercellular Communication | As an early phase of interstitial inflammation preceded peritubular fibrosis in the rat model of AAN, the aim was to investigate the presence of inflammatory cells in human AAN. | 20459552 |
| Interstitial inflammation | Altered Intercellular Communication | Reports of confirmed cases and case series of AAN were reviewed in terms of interstitial inflammation and found to have very conflicting results. | 20459552 |
| Inflammation, Hepatic inflammation, Hypomagnesemia | Altered Intercellular Communication | Hypomagnesemia is defined by serum magnesium concentrationsor=40 U/L, and systemic inflammation by serum high-sensitivity C reactive protein (hs-CRP) concentration>or=3 mg/L. | 20460213 |
| Single organ dysfunction, Inflammation, Pancreatitis, Acute | Altered Intercellular Communication | Angiopoietin-2, a regulator of vascular permeability in inflammation, is associated with persistent organ failure in patients with acute pancreatitis from the United States and Germany. | 20461065 |
| Inflammation | Altered Intercellular Communication | A fistulectomy was performed and the pathological study showed a granulomatous-tuberculous chronic inflammation. | 20461312 |
| Inflammation | Altered Intercellular Communication | Recent data suggest a possible role for inflammation in this disease process. | 20462916 |
| Inflammation, Idiopathic Pulmonary Fibrosis, Traumatic injury | Altered Intercellular Communication | Idiopathic pulmonary fibrosis (IPF) is caused by alterations in expression of proteins involved in multiple pathways, including matrix deposition, inflammation, injury, and repair. | 20463180 |
| Inflammation, Malnutrition | Altered Intercellular Communication | Malnutrition, inflammation, and lipids in a cohort of dialysis patients. | 20463430 |
| Inflammation, Cerebrovascular accident | Altered Intercellular Communication | Previous studies implicated acetylcholinesterase (AChE) involvement in stroke, and circulating AChE activity reflects inflammatory response, since acetylcholine suppresses inflammation. | 20464061 |
| Inflammation, Pseudoaneurysm | Altered Intercellular Communication | In the absence of clinical signs of inflammation, this pseudoaneurysm was successfully treated by ultrasound-guided thrombin injection. | 20464675 |
| Gingivitis, Gingival Hemorrhage | Altered Intercellular Communication | A 13-year-old African American male presented with severe gingival inflammation, generalized gingival bleeding, and tooth looseness. | 20465032 |
| Inflammation, Primary malignant neoplasm | Altered Intercellular Communication | C-reactive protein (CRP), a representative marker for inflammation, is known for its association with disease progression in many cancer types. | 20465852 |
| Neutrophilia (finding) | Altered Intercellular Communication | The lesions were largely devoid of dermal, septal, or lobular neutrophilic or lymphocytic inflammation. | 20466175 |
| Inflammation | Altered Intercellular Communication | We hypothesize that the elevated apoB phenotype may be key therapeutic target to reduce obesity-associated inflammation and IR maximally by hypocaloric-dietary-interventions. | 20466372 |
| Inflammation, Atrial thrombosis, Non-rheumatic atrial fibrillation | Altered Intercellular Communication | Systemic inflammation and left atrial thrombus in patients with non-rheumatic atrial fibrillation. | 20466519 |
| Inflammation | Altered Intercellular Communication | There is an apparent link between thrombogenesis and inflammation. | 20466519 |
| Inflammation, Blood Clot, Atrial Fibrillation by ECG Finding | Altered Intercellular Communication | We hypothesized that systemic inflammation [as indicated by C-reactive protein (CRP)] would be related to the presence of left atrial (LA) thrombus in patients with atrial fibrillation (AF). | 20466519 |
| Inflammation | Altered Intercellular Communication | After TKA, control of local inflammation is much more important than control of systemic inflammation. | 20466551 |
| AVP gene | Altered Intercellular Communication | Recent cases of this disorder in which the pituitary gland was affected include cases of diffuse enlargement of the pituitary and/or its stalk associated with central diabetes insipidus and/or impaired anterior hormone production. | 20467161 |
| Inflammation, Thrombus, Dental Plaque | Altered Intercellular Communication | The serum markers of platelet activation (sP-selectin), inflammation (TNF-alpha and erythrocyte sedimentation rate), thrombotic state (fibrinogen) and plaque disruption were significantly higher in both UA and AMI patients compared to the healthy controls. | 20467748 |
| Inflammation, Endothelial dysfunction | Altered Intercellular Communication | Haemodialysis induces endothelial dysfunction by oxidation and inflammation. | 20470276 |
| Inflammation, Endothelial dysfunction | Altered Intercellular Communication | Haemodialysis caused a significant increase in oxidative stress, inflammation and endothelial dysfunction markers. | 20470276 |
| Inflammation | Altered Intercellular Communication | Elevated visfatin related to markers of inflammation might represent a novel link between inflammation and adipocytokines in dialyzed patients. | 20470278 |
| Inflammation, Malnutrition | Altered Intercellular Communication | High-calcium dialysate: a factor associated with inflammation, malnutrition and mortality in non-diabetic maintenance haemodialysis patients. | 20470300 |
| Inflammation, Malnutrition | Altered Intercellular Communication | Chronic inflammation, which is common in dialysis patients, often causes malnutrition and even protein-energy wasting. | 20470300 |
| Inflammation, Malnutrition | Altered Intercellular Communication | However, the association of high-calcium dialysate with malnutrition and/or inflammation in non-diabetic maintenance haemodialysis patients remains unclear. | 20470300 |
| Inflammation, Malnutrition | Altered Intercellular Communication | Patients with high-calcium dialysate (n = 82) had a higher incidence of malnutrition and inflammation (61.0% vs 44.1% and 43.9%, respectively) than those with standard- and low-calcium dialysate (n = 528 and 107). | 20470300 |
| Inflammation, Malnutrition | Altered Intercellular Communication | The analytical results indicate that high-calcium dialysate is associated with malnutrition and inflammation as well as 2 year mortality in non-diabetic maintenance haemodialysis patients and the findings suggest that this population, even those with optimal mineral balance, should avoid high-calcium dialysate. | 20470300 |
| ARCN1 gene, Chronic Obstructive Airway Disease, Airway structure | Altered Intercellular Communication | Bacterial colonisation in chronic obstructive pulmonary disease (COPD) contributes to airway inflammation and modulates exacerbations. | 20470372 |
| Inflammation | Altered Intercellular Communication | On histopathology transmural acute and chronic inflammation and multiple giant cells were patent in temporal artery wall. | 20470480 |
| Communicable Diseases, Inflammation | Altered Intercellular Communication | The remaining 171 patients (41%) presented with endovascular infection but no evidence of inflammation of the device pocket. | 20470904 |
| Necrotizing granulomatous inflammation, Necrosis | Altered Intercellular Communication | Debridement of the lesion was carried out and tissue sent for histopathological examination which revealed chronic granulomatous inflammation with caseating necrosis. | 20470910 |
| Inflammation | Altered Intercellular Communication | Genes in pathways affecting inflammation, cellular stress and apoptosis are important, and the extent of inflammation in the lung could be affected by polymorphisms modifying these responses. | 20471133 |
| Inflammation, Non-Small Cell Lung Carcinoma | Altered Intercellular Communication | In the present study we have investigated whether a combination of potential functional polymorphisms in genes related to inflammation may modulate risk of NSCLC. | 20471133 |
| Angiolymphoid hyperplasia | Altered Intercellular Communication | Angiofollicular lymphoid hyperplasia (Castleman's disease) is a rare inflammatory condition. | 20471210 |
| Inflammation, Data types - Address | Altered Intercellular Communication | Ample evidence has shown that inflammation and reactive oxygen species (ROS) increase in the AD patient's brain. | 20471471 |
| Inflammation | Altered Intercellular Communication | An in vivo xenograft model showed that host IL6R expression is also increased and regulated by tumor-associated inflammation. | 20471626 |
| Uveitis | Altered Intercellular Communication | A 64-year-old white man from Southern California presented with chronic intraocular inflammation in the right eye that had lasted 18 months. | 20471688 |
| Anemia, Chronic Kidney Diseases | Altered Intercellular Communication | Chronic protein-energy wasting, termed malnutrition-inflammation complex syndrome, is frequent in patients with chronic kidney disease and is associated with anemia, morbidity, and mortality in patients on maintenance dialysis therapy. | 20471737 |
| Inflammation, Tumor necrosis, Malnutrition | Altered Intercellular Communication | Markers of inflammation and malnutrition, including serum C-reactive protein, interleukin 6, tumor necrosis factor alpha, serum leptin, prealbumin, body mass index, and abdominal circumference. | 20471737 |
| Inflammation, Malnutrition | Altered Intercellular Communication | A structural equation model with 2 latent variables (malnutrition and inflammation factor) showed good fit to the observed data. | 20471737 |
| Inflammation, Cachexia | Altered Intercellular Communication | Our results confirm that MIS reflects both energy-protein wasting and inflammation in kidney transplant recipients. | 20471737 |
| Inflammation, Ischemic stroke | Altered Intercellular Communication | We hypothesized that polymorphisms in 5 genes related to thrombolytic and inflammation pathways will independently influence occurrence, severity, and 3-month functional outcome in patients with ischemic stroke. | 20472470 |
| Refractory anemias, Inflammation | Altered Intercellular Communication | One possible mechanism to explain the association between reduced FCGR3B CN and RA is the reduced clearance of immune complex during inflammation. | 20472591 |
| Degenerative polyarthritis, Pain Distress Question, Inflammation | Altered Intercellular Communication | Pain in hand osteoarthritis is associated with inflammation: the value of ultrasound. | 20472595 |
| Pain Distress Question, Synovial Hypertrophy, Inflammation, 4-hydroxy-2-oxovalerate aldolase activity, effusion | Altered Intercellular Communication | GS synovitis, effusion, synovial thickening and PDS are associated with pain in HOA, suggesting a role for inflammation. | 20472595 |
| vascular inflammations, Hyperplastic Polyp | Altered Intercellular Communication | The aim of the study was to establish MP as surrogate markers for platelet, leukocyte and endothelial activation in VAD patients predicting platelet activation and vascular inflammation. | 20472650 |
| vascular inflammations | Altered Intercellular Communication | VAD patients had significantly increased levels of platelet microparticles (PMP) (VAD 1705+/-1100 cpm vs. co: 527+/-238 cpm, P=0.002), leukocyte microparticles (LMP) (VAD 43+/-16 cpm vs. co: 18+/-8 cpm, P<0.001) and endothelial microparticles (EMP) (VAD 135+/-66 cpm vs. co: 46+/-23 cpm, P<0.001) indicating enhanced vascular inflammation and pro-coagulation. | 20472650 |
| Airway structure, mucus secretion | Altered Intercellular Communication | TRQI could improved the Chinese medical signs and symptoms in the patients with AECOPD, possibly because of the decreasing plasma levels of IL-8 and NE which could improve response to airway inflammation and mucus hypersecretion. | 20473738 |
| Gingivitis, Peri-implant mucositis | Altered Intercellular Communication | The most common complications associated with both treatments were gingival inflammation and peri-implant mucositis. | 20476636 |
| Communicable Diseases, Inflammation | Altered Intercellular Communication | The metabolism of the trace elements is altered in infection or inflammation. | 20476645 |
| Inflammation | Altered Intercellular Communication | The extent of BOP exhibited a significant positive correlation with IL-18 in the Spearman rank correlation analysis (P = 0.039), which indicated a correlation between periodontal inflammation and systemic IL-18 levels. | 20476884 |
| Inflammation, Chronic Obstructive Airway Disease, Malnutrition, Obesity | Altered Intercellular Communication | The obesity paradox was verified and may be partly explained by low BMI mediated by malnutrition and systemic inflammation due to PAD or chronic obstructive pulmonary disease. | 20478682 |
| Inflammation, Primary malignant neoplasm | Altered Intercellular Communication | Therefore, a detailed understanding of factors and mechanisms associated with the processes leading from inflammation to cancer could improve the therapeutic strategies against this disease. | 20478763 |
| Inflammation, Primary malignant neoplasm | Altered Intercellular Communication | This could lead to better definition of the disease state, and to an increased understanding of the relationships between chronic inflammation and cancer. | 20478763 |
| Fibrosis Assessment, Nephritis, Kidney Diseases | Altered Intercellular Communication | In animal models, interstitial angiotensin II (ang II) and AT1 receptor (AT1R) are key mediators of renal inflammation and fibrosis in progressive chronic nephropathies. | 20478903 |
| Pneumonitis, Blood Coagulation Disorders | Altered Intercellular Communication | Supernatant of stored platelets causes lung inflammation and coagulopathy in a novel in vivo transfusion model. | 20479286 |
| Pneumonitis | Altered Intercellular Communication | In healthy rats, transfusion of aged PLTs caused mild lung inflammation. | 20479286 |
| Pneumonitis | Altered Intercellular Communication | We conclude that transfusion of aged PLTs induces lung inflammation in healthy rats. | 20479286 |
| Crohn Disease, Specimen Type - Fistula, Stenosis | Altered Intercellular Communication | Magnetic resonance enterography demonstrated active Crohn disease in 57.5% of patients, chronic changes of Crohn disease without active inflammation (eg, stricture, fistula, or abscess) in 12.5% of cases, and no evidence of Crohn disease in 30% of cases. | 20479346 |
| Cholecystitis | Altered Intercellular Communication | Subsequent reinterpretation and additional imaging including magnetic resonance imaging suggested that the uptake in the liver was likely due to adjacent gallbladder inflammation. | 20479586 |
| Ulcerative Colitis, Colitis | Altered Intercellular Communication | We believe that severe colonic inflammation from UC was closely associated with the onset of ARDS of the patient. | 20480533 |
| Respiratory Distress Syndrome, Adult, Colitis | Altered Intercellular Communication | Both colonic inflammations and ARDS symptoms of the patient were resistant to any medical treatment including corticosteroids and antibiotics. | 20480533 |
| Inflammation, Fasciitis | Altered Intercellular Communication | Magnetic resonance imaging (MRI) revealed strong inflammation along the entire fascia of the right femur and necrotizing fasciitis. | 20480846 |
| Retinal Detachment, Inflammation | Altered Intercellular Communication | Following treatment with radiotherapy and rituximab, the patient's intraocular inflammation and retinal detachment resolved. | 20482392 |
| Inflammatory abnormality of the eye | Altered Intercellular Communication | Considering its safety profile, further studies are needed to refine its mechanism of action, optimal indications, and dosing in ocular inflammation. | 20482403 |
| Autoimmune Diseases, Inflammation, Necrotizing vasculitis | Altered Intercellular Communication | Necrotizing vasculitis is a complex phenomenon because of an inflammation of small and larger vessels with polymorph infiltration within the vessel walls and leukocytoclasis, occurring in several autoimmune diseases. | 20482568 |
| Inflammation | Altered Intercellular Communication | It has been hypothesized that intermittent peripheral EBV reactivation may drive continuing central inflammation. | 20482607 |
| Inflammation, Knee joint | Altered Intercellular Communication | Sixty-two (74.7%) knee joints were found clinically involved, while at least one US finding indicative of joint inflammation was obtained in 70 (84.3%) knee joints. | 20483039 |
| Inflammation, Metabolic Syndrome X, Dyslipidemias, Diabetes Mellitus, Depression, CTCAE, Obesity, Hypertension, CTCAE, Chronic Kidney Diseases | Altered Intercellular Communication | We determined disparities in major conventional (hypertension, dyslipidemia, smoking and diabetes), other conventional (underweight, obesity, metabolic syndrome, chronic kidney disease, alcohol use, tension, depression and body height) and non-conventional (current and cumulative inflammation markers) cardiovascular risk factors between 424 consecutive public and 202 private healthcare patients in mixed regression models. | 20483045 |
| Necrotizing granulomatous inflammation, Neurologic Deficits | Altered Intercellular Communication | We hypothesize that meningeal granulomatous inflammation compressed the exiting anterior roots which resulted in motor dysfunction with preservation of peripheral sensory fibers. | 20483179 |
| Inflammation, Campylobacter infection, Infection caused by Helicobacter pylori | Altered Intercellular Communication | The grades of neutrophil activity (p<0.001) and chronic inflammation (p<0.001) were lower for Campylobacter infection than for East Asian CagA H. pylori-related infection. | 20483675 |
| Communicable Diseases, Inflammation, Infection caused by Helicobacter pylori | Altered Intercellular Communication | C. hyointestinalis is the most common cause of non-H. pylori-related Giemsa positive infection, and is associated with lower grades of neutrophil activity and chronic inflammation than East Asian CagA H. pylori-related infection. | 20483675 |
| Inflammation | Altered Intercellular Communication | The mechanism that may trigger human AT inflammation on a cellular level still remains largely unknown. | 20484010 |
| Inflammation | Altered Intercellular Communication | Open heart surgery results in an extensive acute systemic inflammation. | 20484010 |
| Inflammation, Coronary heart disease, Choline Dehydrogenase, Mitochondrial | Altered Intercellular Communication | Inflammation plays a central role in the development and progression of coronary heart disease (CHD). | 20484148 |
| Inflammation, Carcinogenesis | Altered Intercellular Communication | Serum interleukin-6 (IL-6), a proinflammatory cytokine, is considered an indicator of inflammation and may be an indicator of colorectal carcinogenesis given that inflammation can promote carcinogenesis. | 20484173 |
| Inflammation, Carcinogenesis | Altered Intercellular Communication | Flavonols, which can be found in fruits and vegetables, may inhibit colorectal carcinogenesis partly by inhibiting inflammation. | 20484173 |
| Sepsis, Inflammation, Observation Method - Coagulation | Altered Intercellular Communication | In sepsis, coagulation and inflammation are activated to restore homeostasis, but it is not known whether sepsis also alters tissue regeneration processes such as skin collagen synthesis. | 20484539 |
| Inflammation, Neoplasms | Altered Intercellular Communication | Copy number variation was associated with differences in tumor cell type, but not with differences in tumor pigmentation or reactive inflammation. | 20484589 |
| Inflammation, Ischemic stroke | Altered Intercellular Communication | Early inflammation has been suggested as an important factor contributing to unfavorable prognosis after acute ischemic stroke. | 20484906 |
| Inflammation, Brain Injuries, Ischemic stroke, Cerebrovascular accident | Altered Intercellular Communication | Our data show important differences in the early time course of several potential markers for the complex network of inflammation and brain damage after ischemic stroke depending on stroke outcome. | 20484906 |
| Uterine Cervicitis, Swallowing painful | Altered Intercellular Communication | One month after the surgery, the patient came to the emergency department complaining about progressive anterior cervical inflammation, with odynophagia. | 20485050 |
| Inflammation, Neoplasms | Altered Intercellular Communication | They may mimic chronic inflammation and be misdiagnosed, delaying treatment and allowing the tumor to devastate the visual system. | 20485052 |
| Inflammation, Diverticulitis | Altered Intercellular Communication | Acute uncomplicated diverticulitis (AUD) may show histologic and serologic signs of inflammation. | 20485187 |
| Inflammation, Histologic | Altered Intercellular Communication | CRP was the most sensitive marker of mild-moderate histologic damage, as it was increased in 4/10 (40%) patients scoring 0 or 1 in neutrophilic infiltrate (absence of mild active inflammation) (P=0.005). | 20485187 |
| Psoriasis, Ulcerative Colitis, Tumor necrosis, Rheumatoid Arthritis, Crohn Disease | Altered Intercellular Communication | Tumour necrosis factor-alpha (TNFalpha) has an important role in the pathogenesis of inflammatory conditions such as rheumatoid arthritis, Crohn's disease, ulcerative colitis and psoriasis. | 20485705 |
| Adenocarcinoma, Inflammation, HIV Coinfection, Empyema | Altered Intercellular Communication | Histologically confirmed causes of the effusion were; metastatic adenocarcinoma in two(25%) of the cases; chronic nonspecific inflammation in another two(25%) and tuberculous empyema thoracis in three(37.5%) one of whom had TB and HIV coinfection and one(12.5%) of chronic bacterial parapneumonic empyema. | 20486093 |
| Inflammation | Altered Intercellular Communication | Systemic markers of inflammation are associated with cardiac allograft vasculopathy and an increased intimal inflammatory component. | 20486911 |
| Granulomatous inflammation, Inflammation | Altered Intercellular Communication | The pathological examination revealed granulomatous inflammation, acute and chronic inflammation or both. | 20487616 |
| Data types - Address, neuropathology disease | Altered Intercellular Communication | In summary, our findings indicate that neurosteroids are altered in temporal cortex in patients with AD and related to neuropathological disease stage. | 20488256 |
| Data types - Address | Altered Intercellular Communication | Neurosteroids may be relevant to the neurobiology and therapeutics of AD. | 20488256 |
| Inflammation | Altered Intercellular Communication | The patient was treated with intranasal antrostomy in which the underlying dental cause of the inflammation was also removed. | 20489466 |
| Xanthogranulomatous inflammation, Eyelid Sebaceous Gland Carcinoma | Altered Intercellular Communication | Sebaceous cell carcinoma of the eyelid: a rapidly enlarging lesion with massive xanthogranulomatous inflammation. | 20489549 |
| Inflammation, Atherosclerosis | Altered Intercellular Communication | Levels of circulating anti-Hsp60 antibodies may constitute a marker of inflammation in atherosclerosis. | 20490736 |
| Inflammation, Lumbar radiculopathy | Altered Intercellular Communication | The duration of nerve root block showed a negative correlation with the concentrations of acetate in CSF of the patients in Group R. In patients with lumbar radiculopathy, there is a possibility of increased aerobic metabolic activity or decreased gluconeogenic activity in patients with shorter symptom duration, and increased aerobic metabolic activity in patients with severe inflammation around a nerve root. | 20490871 |
| Inflammation, Neurotoxicity Syndromes | Altered Intercellular Communication | Post-stroke inflammation may induce upregulation of the kynurenine (KYN) pathway for tryptophan (TRP) oxidation, resulting in neuroprotective (kynurenic acid, KA) and neurotoxic metabolites (3-hydroxyanthranillic acid, 3-HAA). | 20490917 |
| Coronary Artery Disease | Altered Intercellular Communication | Patients with acute or chronic inflammatory conditions, coronary artery disease or creatinine clearance below 50 mL/min were excluded. | 20491014 |
| ARCN1 gene, Inflammation | Altered Intercellular Communication | Preasumably, chronic inflammation in bronchial tree in course of COPD could be predisposing factor for p53 mutation and synthesis of pathological p53 protein. | 20491334 |
| Inflammation | Altered Intercellular Communication | Although the precise mechanism of this relationship remains unclear, the role of chronic low-grade inflammation, chronic oxidative and mechanical stress and an increase in VEGF is discussed. | 20491689 |
| Refractory anemias, Rheumatoid Arthritis, destruction joint, Have Autoimmune or Inflammatory Condition, Hyperplasia | Altered Intercellular Communication | Main features of rheumatoid arthritis (RA), hyperplasia of fibroblast-like synoviocytes (FLS) and joint destruction are caused by inflammatory cytokines produced in chronic autoimmune inflammation. | 20491788 |
| Malnutrition, Inflammation, Calcification of coronary artery, Renal Osteodystrophy | Altered Intercellular Communication | Malnutrition, inflammation, and renal osteodystrophy parameters with resultant coronary calcification (CC) are associated with increased cardiovascular mortality in adults. | 20491972 |
| Inflammation, Stasis, Intrahepatic Route of Drug Administration | Altered Intercellular Communication | Although the pathogenesis of IH is unknown, a role for lymphatic stasis secondary to chronic inflammation or surgery has been suggested. | 20492077 |
| Eosinophilic disorder, Inflammation | Altered Intercellular Communication | IL-17A is involved in inflammation and IL-17E is able to induce Th2 cytokine production and eosinophilia. | 20492545 |
| Heart failure, Myocarditis, Muscular Dystrophy, Duchenne | Altered Intercellular Communication | Myocardial inflammation in Duchenne Muscular Dystrophy as a precipitating factor for heart failure: a prospective study. | 20492678 |
| Heart failure, Myocarditis, Doctor of Dental Medicine | Altered Intercellular Communication | We evaluated the role of myocardial inflammation as a precipitating factor in the development of heart failure in DMD. | 20492678 |
| Heart failure, Myocarditis, Doctor of Dental Medicine | Altered Intercellular Communication | DMD patients with myocardial inflammation documented by CMR had a rigorous progression to heart failure. | 20492678 |
| Inflammation, Anemia | Altered Intercellular Communication | However, the strongest correlation was observed between 30 and 60 min measurements (r=0.926, p<0.001), irrespective of age, sex and presence of anaemia or of inflammation. | 20493427 |
| ARCN1 gene, Inflammation | Altered Intercellular Communication | Only some variables that would represent a higher chronic inflammation and a lower exercise tolerance showed a statistical tendence in the dead patients group in a exacerbation of COPD. | 20494350 |
| Inflammation, Obesity | Altered Intercellular Communication | Low grade inflammation is a key feature of central obesity, characterized by elevated plasma levels of C-reactive protein (CRP). | 20494358 |
| Inflammation, Cardio-Renal Syndrome, LUC7L3 gene, Chronic heart failure, Anemia, Chronic Kidney Diseases | Altered Intercellular Communication | The combination of chronic kidney disease (CKD), chronic heart failure (HF), and anaemia, the so-called cardio-renal-anaemia syndrome (CRA) is associated with dysregulation of erythropoietin levels and inflammation. | 20495204 |
| Necrotizing granulomatous inflammation | Altered Intercellular Communication | Twelve cases of chronic granulomatous inflammation of musculoskeletal tissues were used for the study. | 20495271 |
| Inflammation | Altered Intercellular Communication | Some inflammation factors have been shown to accelerate type 2 diabetes macrovascular complication (T2DMC). | 20495833 |
| Inflammation, Retinitis Pigmentosa, polychondritis, Immune-mediated | Altered Intercellular Communication | Relapsing polychondritis (RP) is a rare immune-mediated disease which is associated with inflammation in cartilaginous tissue throughout the body. | 20495939 |
| Inflammation, Hemorrhage, Communicable Diseases, Pituitary Apoplexy, Pituitary Adenoma, Rathke Cleft Cysts | Altered Intercellular Communication | Although pituitary apoplexy due to hemorrhage, inflammation, or infection due to an underlying Rathke's cleft cyst is difficult to diagnose pre-operatively, Rathke's cleft cyst should be included in the differential diagnosis, and early surgical treatment is needed, as for pituitary apoplexy caused by pituitary adenoma. | 20495985 |
| Dystrophy, Inflammation, Myotoxicity | Altered Intercellular Communication | Myofiber necrosis without prominent inflammation is a nonspecific finding in patients with dystrophies and toxic or immune-mediated myopathies. | 20496415 |
| Necrotizing granulomatous inflammation | Altered Intercellular Communication | Granulomatous orbital inflammation associated with intraorbital titanium-impregnated acetate fiber. | 20497088 |
| Granulomatous inflammation, Orbital Pseudotumor | Altered Intercellular Communication | Orbital biopsy revealed granulomatous inflammation consistent with idiopathic orbital inflammatory syndrome (IOIS), or orbital pseudotumor. | 20497088 |
| Inflammatory Bowel Diseases | Altered Intercellular Communication | It is important for dermatologists and dermatopathologists to be aware of the occurrence of IR-LPD in patients being treated for inflammatory conditions, including inflammatory bowel disease. | 20497356 |
| Inflammation, Observation Method - Coagulation, Community acquired pneumonia | Altered Intercellular Communication | Coagulation and inflammation biomarkers may help predict the severity of community-acquired pneumonia. | 20497384 |
| Inflammation, Observation Method - Coagulation, Community acquired pneumonia | Altered Intercellular Communication | There are limited data on the relationship between the severity of community-acquired pneumonia (CAP) and biomarkers of inflammation and coagulation. | 20497384 |
| Inflammation, Atherosclerosis | Altered Intercellular Communication | At the time of the index procedure 21/23 (91,3%) patients required dialysis, 15/22 patients (68,2%) showed signs and symptoms of atherosclerosis and 17/20 (76,5%) of inflammation. | 20497754 |
| Inflammation, Tuberculosis, Communicable Diseases, Hepatitis C, Hypoalbuminemia | Altered Intercellular Communication | We excluded patients who had infectious risk (hepatitis C or B positive, HIV positive, purified protein derivative (PPD) positive or having a history of tuberculosis, having a tunneled dialysis catheter) to find patients having both hypoalbuminemia and inflammation. | 20497755 |
| Giant Cell Arteritis, Vasculitis, GCA gene | Altered Intercellular Communication | To define the specificity and extent of duplex sonography (DS) findings suggestive of vessel wall inflammation in patients with giant cell arteritis (GCA). | 20498213 |
| Refractory anemias, Have Autoimmune or Inflammatory Condition, Diastolic dysfunction | Altered Intercellular Communication | RA duration and IL-6 are independently associated with diastolic dysfunction, suggesting the impact of chronic autoimmune inflammation on myocardial function in RA. | 20498217 |
| Adenocarcinoma, Inflammation | Altered Intercellular Communication | We reported that adenocarcinomas with a bubblelike appearance (BLA) appear similar to old inflammation (J Comput Assist Tomogr 2009;33:42-48). | 20498546 |
| Inflammatory Bowel Diseases, Gastrointestinal inflammation | Altered Intercellular Communication | Calprotectin, a major cytosolic protein of neutrophils, is increased in inflammatory bowel disease (IBD) and may be considered a suitable marker of intestinal inflammation. | 20499020 |
| Inflammation | Altered Intercellular Communication | Presence, degree and length of wall inflammation were evaluated. | 20499020 |
| Inflammation | Altered Intercellular Communication | The MRI degree of wall inflammation was graded with a 0-3 scoring system (0=absent 1=light 2=moderate 3=severe) by considering findings observed on T1 post Gd and T2 fat-suppressed images, as well as the degree of wall thickness. | 20499020 |
| hepcidin, Anemia | Altered Intercellular Communication | Hepcidin is a key hormone governing mammalian iron homeostasis and may be directly or indirectly involved in the development of most iron deficiency/overload and inflammation-induced anemia. | 20499129 |
| Inflammation, Iron deficiency anemia, Anemia, Chronic disease, hepcidin | Altered Intercellular Communication | To characterize serum hepcidin, iron and inflammatory indicators associated with anemia of chronic disease (ACD), we studied ACD, ACD concomitant iron-deficiency anemia (ACD/IDA), pure IDA and acute inflammation (AcI) patients and analyzed the associations between hepcidin levels and inflammation parameters in various types of anemia. | 20499129 |
| hepcidin, Anemia | Altered Intercellular Communication | Hepcidin is a key hormone governing mammalian iron homeostasis and may be directly or indirectly involved in the development of most iron deficiency/overload and inflammation-induced anemia. | 20499129 |
| Inflammation, Carcinogenesis | Altered Intercellular Communication | Chronic inflammation is suspected to have a role in breast carcinogenesis. | 20499154 |
| Inflammation, Diabetes Mellitus, Non-Insulin-Dependent, Chronic Kidney Diseases | Altered Intercellular Communication | Chronic low-grade inflammation may induce chronic kidney disease in patients with type 2 diabetes. | 20499416 |
| Inflammation | Altered Intercellular Communication | The patients suffering from the diseases not related to the chronic inflammation of the paranasal sinuses. | 20500579 |
| Inflammation, Chronic Obstructive Airway Disease | Altered Intercellular Communication | Systemic inflammation in chronic obstructive pulmonary disease: a population-based study. | 20500811 |
| ARCN1 gene, Inflammation | Altered Intercellular Communication | Our results provide population-based evidence that COPD is independently associated with low-grade systemic inflammation, with a different inflammatory pattern than that observed in healthy subjects. | 20500811 |
| Inflammation, Critical Illness | Altered Intercellular Communication | Ghrelin is not correlated to markers of inflammation or hepatic function in critically ill patients. | 20500817 |
| Gastric Emptying, Inflammation | Altered Intercellular Communication | Mechanisms of gastric emptying disturbances in chronic and acute inflammation of the distal gastrointestinal tract. | 20501434 |
| Inflammation | Altered Intercellular Communication | It is unclear why patients with inflammation of the distal bowel complain of symptoms referable to the upper gastrointestinal tract, specifically to gastric emptying (GE) disturbances. | 20501434 |
| Fibrosis Assessment | Altered Intercellular Communication | The pathways include (a) alveolar collapse, (b) incorporation of fibroblastic material into alveolar walls, and (c) cigarette smoke-related inflammation and fibrosis. | 20501710 |
| Carcinoma of lung, Pneumonitis, Infection | Altered Intercellular Communication | Our results highlight the potential for lung cancer risk reduction through treatments targeted toward C. pneumoniae infections and chronic pulmonary inflammation. | 20501758 |
| Increased insulin level, Inflammation, Colorectal Carcinoma, Obesity | Altered Intercellular Communication | Serum adiponectin, leptin, C-peptide, and homocysteine are indicators for obesity, hyperinsulinemia, and chronic inflammation, which have all been associated with colorectal cancer. | 20501764 |
| Inflammation, Leukocytosis, Anemia, Anorexia, Thrombocytosis, Fatigue | Altered Intercellular Communication | Within one week, her fatigue and anorexia markedly improved, and her laboratory abnormalities, including anemia, thrombocytosis, leukocytosis, and elevated markers of inflammation, all resolved. | 20501803 |
| Inflammation | Altered Intercellular Communication | The degree of inflammation during the acute phase was higher in patients who had increased urinary excretion of a(1)-microglobulin 6 years later compared with those with no a(1)-microglobulin excretion. | 20502044 |
| Inflammation, Anemia | Altered Intercellular Communication | A significant vitamin D3 deficiency observed in the majority of patients undergoing long-term HD contributes to the development of chronic inflammation, anemia, and indirectly, to endothelial cell injury. | 20502401 |
| Inflammation, Thrombosis | Altered Intercellular Communication | During the past decade, the role of inflammation in the pathophysiology of arterial thrombosis has been elucidated. | 20502419 |
| Inflammation, Venous Thrombosis | Altered Intercellular Communication | However, little is known about the relationship between inflammation and venous thrombosis. | 20502419 |
| Inflammation, Blood Clot | Altered Intercellular Communication | Recently, inflammation has been accepted as a possible mechanism through which different risk factors trigger thrombus formation in veins. | 20502419 |
| Venous Thrombosis, Inflammation, Endothelial dysfunction | Altered Intercellular Communication | Patients with idiopathic venous thrombosis have increased levels of circulating markers of inflammation and blood markers of endothelial dysfunction. | 20502419 |
| Inflammation, Venous Thrombosis, Endothelial dysfunction | Altered Intercellular Communication | The interrelationship between inflammatory markers and markers of endothelial dysfunction favour the hypothesis that inflammation could be involved in the etiopathogenesis of idiopathic venous thrombosis. | 20502419 |
| Inflammation, Neoplasm Metastasis, Neoplasms | Altered Intercellular Communication | There are several functions of the SAA protein, described in the context of inflammation, that are compatible with the mechanism of tumour invasion and metastasis. | 20502455 |
| Suppurative inflammation | Altered Intercellular Communication | The CSF cytological and biochemical findings were both positive for purulent inflammation in 76 % of patients. | 20503157 |
| Inflammation, Bacterial Infections | Altered Intercellular Communication | To evaluate the penetration of ceftriaxone into the cerebrospinal fluid (CSF) in patients with invasive bacterial infection and to define correlation between the penetration and laboratory markers of inflammation. | 20503158 |
| Airway structure, Cystic Fibrosis | Altered Intercellular Communication | Effects of a short-term rehabilitation program on airway inflammation in children with cystic fibrosis. | 20503278 |
| Communicable Diseases, Fibrosis Assessment | Altered Intercellular Communication | Respiratory therapy in cystic fibrosis (CF) consists of airway clearance, infection control, and reduction of airway inflammation. | 20503278 |
| Inflammation, Carcinogenesis | Altered Intercellular Communication | Sustained chronic inflammation in the prostate promotes prostate carcinogenesis. | 20503397 |
| Inflammation, Diabetes Mellitus, Non-Insulin-Dependent | Altered Intercellular Communication | Subclinical inflammation may be a mechanism linking air pollution with type 2 diabetes. | 20504758 |
| Inflammation, Endothelial dysfunction | Altered Intercellular Communication | Plasma protein growth arrest-specific 6 levels are associated with altered glucose tolerance, inflammation, and endothelial dysfunction. | 20504897 |
| Inflammation, Endothelial dysfunction | Altered Intercellular Communication | Plasma Gas6 is associated with altered glucose tolerance, inflammation, and endothelial dysfunction. | 20504897 |
| Diabetes Mellitus, Non-Insulin-Dependent, Inflammation, Endothelial dysfunction | Altered Intercellular Communication | It also may represent a novel independent risk factor of type 2 diabetes and a potential surrogate marker of inflammation and endothelial dysfunction. | 20504897 |
| Inflammation, Appendicitis, CTCAE | Altered Intercellular Communication | CT reports were reviewed, and the likelihood of appendicitis was assigned a score on a five-point scale: score 1, definitely absent; score 2, nonvisualized appendix with no secondary signs of inflammation; score 3, equivocal; score 4, probable; and score 5, definitely present. | 20505066 |
| Conjunctivitis | Altered Intercellular Communication | Recurrence was associated with severe conjunctival inflammation and severe trichiasis (>10 lashes) at baseline. | 20505197 |
| Keratitis | Altered Intercellular Communication | A cascade involving these biologically active factors may regulate scleral and corneal inflammation. | 20505198 |
| Inflammation, Hematoma | Altered Intercellular Communication | The epidural hematoma was probably caused by the spread of inflammation from the sphenoid sinus. | 20505297 |
| Inflammation, Discitis | Altered Intercellular Communication | In cases of spondylodiscitis, spine surgeons should be careful about inflammation of major vessels with friable vessel walls anterior to the vertebrae. | 20505562 |
| Inflammation, Prostate carcinoma | Altered Intercellular Communication | Evidence from laboratory studies suggests that chronic inflammation plays an important role in prostate cancer aetiology. | 20506261 |
| Inflammation, Fibrosis Assessment | Altered Intercellular Communication | ERp57 expression was detected in 16 out of 17 patient biopsies and correlated with inflammation grades or fibrosis stages, while in 5 normal biopsies ERp57 expression was not detectable in hepatocytes. | 20506389 |
| Suppurative inflammation, Community-Acquired Infections, Pneumonia | Altered Intercellular Communication | For some years, an increasing incidence of MRSA outside the hospital environment (Community-acquired or Community-Associated MRSA, CA-MRSA) has been observed all over the world, which, contrary to the hospital strains, produces the leukocytotoxic toxin PVL and causes purulent inflammations of the skin and necrotizing pneumonia. | 20506711 |
| Sarcoidosis, Inflammatory abnormality of the eye | Altered Intercellular Communication | Medical records of pediatric patients evaluated between 1987 and 2008 were reviewed to identify those with ocular inflammation in whom a diagnosis of sarcoidosis was considered. | 20506967 |
| Air Embolism, Inflammation | Altered Intercellular Communication | Although hemodynamic compromise has long been regarded as the main mechanism-particularly with deep watershed infarction-there is some contradictory evidence from clinical and pathological studies for a role of microembolism, thought to result from plaque inflammation. | 20508190 |
| Inflammation, Carotid Stenosis, Cerebrovascular accident | Altered Intercellular Communication | In 16 consecutive patients with recent transient ischemic attack/minor stroke and ipsilateral 50% to 99% carotid stenosis, we prospectively obtained (1) plaque inflammation mapping with (18)F fluorodeoxyglucose positron emission tomography; (2) brain MRI and perfusion MR; and (3) transcranial Doppler detection of microembolic signals (MES). | 20508190 |
| Inflammation | Altered Intercellular Communication | We found the expected significant relationship between (1) degree of stenosis and severity of distal hemodynamic impairment in the watershed areas; and (2) degree of in vivo plaque inflammation and rate of MES/hr. | 20508190 |
| Inflammation, Stenosis, Air Embolism, Watershed infarct, carotid disease | Altered Intercellular Communication | This pilot study supports the idea that in symptomatic carotid disease, deep watershed infarcts result either from hemodynamic impairment secondary to severe lumen stenosis or from microembolism secondary to plaque inflammation. | 20508190 |
| Pneumonitis, Blood Coagulation Disorders | Altered Intercellular Communication | Supernatant of aged erythrocytes causes lung inflammation and coagulopathy in a "two-hit" in vivo syngeneic transfusion model. | 20508493 |
| Pneumonitis, Blood Coagulation Disorders | Altered Intercellular Communication | In healthy rats, transfusion of aged erythrocytes caused mild pulmonary inflammation but no coagulopathy. | 20508493 |
| Pulmonary Complication | Altered Intercellular Communication | Washing of aged erythrocytes may decrease pulmonary complications in patients with an inflammatory condition who are exposed to a blood transfusion. | 20508493 |
| Inflammation | Altered Intercellular Communication | Histopathologic and immunohistochemical evaluations confirmed that they were both predominantly junctional nevi with conspicuous chronic inflammation. | 20508514 |
| Inflammation, AATF wt Allele, evaporation | Altered Intercellular Communication | These results suggest that inflammation plays a role not only in severe DED but also in moderate evaporative DED. | 20508732 |
| Inflammation, Atrial Fibrillation by ECG Finding | Altered Intercellular Communication | Circulating progenitor cells in patients with atrial fibrillation and their relation with serum markers of inflammation and angiogenesis. | 20508899 |
| Inflammation | Altered Intercellular Communication | Increased levels of inflammation markers and elevated activity of liver enzymes were observed in laboratory tests. | 20509567 |
| Inflammation | Altered Intercellular Communication | The biological significance of this infiltration, very similar to chronic inflammation, is unknown, but it is suspected as being related to the pathogenesis and progression of the BPH. | 20510119 |
| Inflammation, Depressed mood, Carotid Atherosclerosis | Altered Intercellular Communication | Autonomic nervous system, inflammation and preclinical carotid atherosclerosis in depressed subjects with coronary risk factors. | 20510416 |
| Inflammation, Atherosclerosis, Coronary Artery Disease, Depressed mood, Pathologic Intimal Thickening | Altered Intercellular Communication | We investigated the relationship between intima-media thickening (IMT) as an expression of preclinical atherosclerosis and coronary risk factors, including the autonomic nervous system and inflammation markers, in depressed subjects free from coronary artery disease. | 20510416 |
| Inflammation, Coronary Artery Disease, Depression, CTCAE | Altered Intercellular Communication | This is mainly due to patho-physiological mechanisms which connect depression and coronary artery disease, such as inflammation and imbalance of the autonomic nervous system. | 20510416 |
| Inflammation, Pneumothorax, Toxic effect | Altered Intercellular Communication | Acute toxicity included pneumothorax (1.5%) and mucosal inflammation (10%). | 20510543 |
| Granulomatous inflammation, Pericarditis, CTCAE | Altered Intercellular Communication | The presence of granulomatous inflammation on the biopsy and an elevated pericardial adenosine deaminase activity level retrospectively supported the diagnosis of tuberculous pericarditis. | 20510915 |
| Cystic Lesion, Inflammation, Carcinoma | Altered Intercellular Communication | The main cystic lesion was diagnosed to be solid-papillary carcinoma, but the area of the pectoralis muscle was diagnosed to be a "foreign body" inflammation. | 20512549 |
| Inflammation, Mass in breast | Altered Intercellular Communication | It was thought that the compression related to MMG and core needle biopsy induced an injury in the bulky breast mass with leakage of contents into adjacent tissue, resulting in the foreign body inflammation. | 20512549 |
| Bronchi, Asthma, Aspirin-Induced, Pneumonitis, Anguilla island | Altered Intercellular Communication | Aspirin-intolerant asthma (AIA), which is caused by non-steroidal anti-inflammatory drugs (NSAIDs) such as aspirin, causes lung inflammation and reversal bronchi reduction, leading to difficulty in breathing. | 20513247 |
| CLU protein, human, Ischemia, Inflammation, Communicable Diseases | Altered Intercellular Communication | Patients with critical limb ischaemia (CLI) suffer chronic inflammation, repeated infection, require intervention, and can have a protracted hospital stay. | 20513273 |
| Inflammation | Altered Intercellular Communication | OA- and ONFH-affected bone exhibits a similar pro-inflammatory cytokine and collagen expression profile suggesting a relationship on the molecular level of inflammation and collagenous matrix composition between both diseases. | 20514432 |
| Inflammation, Mycobacterium Infections | Altered Intercellular Communication | Multiple mucosal biopsies from the left maxillary sinus revealed necrotizing granulomatous inflammation suspicious of mycobacterial infection. | 20514598 |
| Inflammation | Altered Intercellular Communication | Uric acid is a cardiovascular risk marker associated with oxidative stress and inflammation. | 20515852 |
| Atrial Fibrillation, Inflammation, Atrial Fibrillation by ECG Finding | Altered Intercellular Communication | Recently, atrial fibrillation (AF) has been associated with inflammation and oxidative stress. | 20515852 |
| Inflammation, Viral Encephalitis | Altered Intercellular Communication | The mechanisms underlying inflammation and immune responses in viral encephalitis are not fully understood. | 20516723 |
| Inflammation, Ear Inflammation | Altered Intercellular Communication | Results of diagnostic studies are usually interpreted as middle ear pathology (tubootitis, exudative otitis, middle ear inflammation). | 20517271 |
| Inflammation | Altered Intercellular Communication | T-2 weighted magnetic resonance imaging (MRI) at 8 weeks showed increased signal intensity compatible with inflammation in several pelvic limb muscles. | 20517298 |
| Infection caused by Helicobacter pylori | Altered Intercellular Communication | Our findings strongly indicate a preventive effect of JA intake on CAG by inhibiting H. pylori infection and reducing active mucosal inflammation. | 20517325 |
| Coronary Artery Disease | Altered Intercellular Communication | Inflammation markers in patients with coronary artery disease--comparison of intracoronary and systemic levels. | 20517668 |
| Inflammation, Coronary Artery Disease | Altered Intercellular Communication | Raised levels of inflammation markers are associated with worse prognosis in patients with coronary artery disease. | 20517668 |
| Inflammation, Coronary Artery Disease | Altered Intercellular Communication | We observed that excess circulating inflammation markers, being characteristic of unstable coronary artery disease, are released from noncoronary sources. | 20517668 |
| Inflammation, Coronary heart disease | Altered Intercellular Communication | Thus, it may be speculated that systemic inflammation precedes local inflammation at the plaques, thereby transforming coronary disease from a stable to an unstable form. | 20517668 |
| Degenerative polyarthritis, Inflammation | Altered Intercellular Communication | In conclusion, although synovial inflammation remained active, the MMP-1, COX-2 and IL-1b expression in synovium decreased depending upon the severity of OA, while the TGF-b expression increased. | 20517696 |
| Hemorrhagic pleural effusion, Inflammation | Altered Intercellular Communication | Thoracentesis revealed hemorrhagic pleural effusion which was exudate and lymphocyte predominant, closed pleural biopsy showed chronic inflammation. | 20517734 |
| Erectile dysfunction | Altered Intercellular Communication | Drugs play a role in the pathogenesis of erectile dysfunction, as they can alter hormonal or vascular mechanics needed for achieving or maintaining erection. | 20518197 |
| Atherogenesis, Inflammation, Electrocardiogram: myocardial infarction (finding), Dental Plaque | Altered Intercellular Communication | uPA (urokinase-plasminogen activator) and its receptor (uPAR) have been implicated in a broad spectrum of pathophysiological processes, including fibrinolysis, proteolysis, inflammation, atherogenesis and plaque destabilization, all of which are involved in the pathogenesis of MI (myocardial infarction). | 20518747 |
| Gastroesophageal reflux disease, Inflammation | Altered Intercellular Communication | Transient receptor potential vanilloid-1 (TRPV1) receptor has been implicated in the mechanism of acid induced inflammation in gastro-esophageal reflux disease (GERD). | 20518854 |
| Inflammation, Diabetes Mellitus, Non-Insulin-Dependent, Coronary heart disease | Altered Intercellular Communication | Lung function and risk of type 2 diabetes and fatal and nonfatal major coronary heart disease events: possible associations with inflammation. | 20519659 |
| Inflammation, Diabetes Mellitus, Coronary heart disease, Choline Dehydrogenase, Mitochondrial | Altered Intercellular Communication | We prospectively examined the relationship between lung function and risk of type-2 diabetes and fatal and nonfatal coronary heart disease (CHD) events and investigated the hypothesis that inflammation may underlie these associations. | 20519659 |
| Inflammation, Lung Obstructive Function Score 1, Diabetes Mellitus, Non-Insulin-Dependent, Choline Dehydrogenase, Mitochondrial | Altered Intercellular Communication | Restrictive rather than obstructive impairment of lung function is associated with incident type 2 diabetes (and fatal CHD) with both associations partially explained by traditional and metabolic risk factors and inflammation. | 20519659 |
| Inflammation, Autonomic nervous system disorders | Altered Intercellular Communication | Short-term elevation of ambient particulate air pollution has been associated with autonomic dysfunction and increased systemic inflammation, but the interconnections between these pathways are not well understood. | 20519749 |
| Inflammation | Altered Intercellular Communication | Increased systemic inflammation was defined for subjects within the upper 20% of the distribution for each marker. | 20519749 |
| Inflammation, Autonomic nervous system disorders | Altered Intercellular Communication | Increased systemic inflammation is associated with autonomic dysfunction in the elderly. | 20519749 |
| Inflammation, Disease | Altered Intercellular Communication | Human leukocyte antigen analysis showed B35 and B52, the typical haplotype in cases with coexistence of both diseases and associated sustained inflammation. | 20519817 |
| Inflammatory Bowel Diseases, Inflammation, Ulcerative Colitis | Altered Intercellular Communication | Ulcerative colitis is an inflammatory bowel disease involving superficial inflammation of the mucosa of the colon, rectum, and anus, sometimes including the terminal ileum. | 20520975 |
| Inflammation, Progranulins, Neoplasms, GRN wt Allele | Altered Intercellular Communication | Progranulin (PGRN) is involved in wound repair, inflammation, and tumor formation, but its function in the central nervous system is unknown. | 20522652 |
| Sepsis, Inflammation | Altered Intercellular Communication | During sepsis, activation of phagocytes leads to the overproduction of proinflammatory cytokines, causing systemic inflammation. | 20522778 |
| Airway structure, Allergic asthma, Bronchial Hyperreactivity | Altered Intercellular Communication | Changes in airway inflammation and hyperresponsiveness after inhaled corticosteroid cessation in allergic asthma. | 20523062 |
| Airway structure, Asthma, Bronchial Hyperreactivity | Altered Intercellular Communication | The present study evaluates changes in airway inflammation and hyperresponsiveness in adult patients with asthma after stopping ICS. | 20523062 |
| Skin necrosis, Intraocular inflammation, Oculomotor Nerve Paralysis | Altered Intercellular Communication | After 3 months, visual acuity, all intraocular inflammation, oculomotor nerve palsy, and skin necrosis resolved completely except for a dilated pupil. | 20523258 |
| Refractory anemias, Inflammation, Rheumatoid Arthritis | Altered Intercellular Communication | To compare magnetic resonance imaging (MRI) and ultrasonography (US) in the detection of joint inflammation of rheumatoid arthritis (RA), 6 patients with RA were examined by US and low-field 0.3-T nonenhanced dedicated extremity MRI (compacTscan). | 20524026 |
| Joints, Structure of intercarpal joint, Inferior radioulnar joint structure, PIP gene, Arthritis | Altered Intercellular Communication | Intercarpal joints, radioulnar joints, second through fifth proximal interphalangeal (PIP) joints, and first through fifth metacarpophalangeal (MCP) joints (a total of 132 joints, 22 joints in each patient) were assessed by MRI for presence of joint inflammation. | 20524026 |
| Arthritis, Wrist joint | Altered Intercellular Communication | A total of 156 joints (24 first interphalangeal and radiocarpal joints plus the above 132 joints), were assessed by grayscale US (GS-US) and power Doppler US (PD-US) for presence of joint inflammation by two trained ultrasonographers. | 20524026 |
| Inflammation | Altered Intercellular Communication | ICC was 0.545 for GS-US and 0.807 for PD-US, suggesting specificity of PD-US in detecting joint inflammation. | 20524026 |
| Arthritis | Altered Intercellular Communication | We assessed correlations between joint inflammations on MRI and GS-US/PD-US, and also interobserver correlation between the two ultrasonographers by calculating intraclass correlation coefficients (ICC). | 20524026 |
| Refractory anemias, Inflammation, Rheumatoid Arthritis, Inflammatory disorder | Altered Intercellular Communication | Neutrophils and monocytes play an important role in overt inflammation in chronic inflammatory joint diseases such as rheumatoid arthritis (RA). | 20525314 |
| Inflammation | Altered Intercellular Communication | Identification of the molecular checkpoints critical for completion of the lymphoid neogenesis program should help develop innovative therapeutic strategies to fight chronic inflammation. | 20525884 |
| Inflammatory, Inflammation, Abnormal color | Altered Intercellular Communication | Oral postinflammatory pigmentation (OPP) is a discoloration of the oral mucosa caused by an excess of melanin production and deposition within the basal layer of the epithelium and connective tissue of areas affected by chronic inflammation. | 20526252 |
| Endothelial dysfunction, Diabetes Mellitus | Altered Intercellular Communication | Type-2 diabetes is accompanied by a prothrombotic state influenced by endothelial dysfunction, inflammatory condition and platelet hyperreagibility. | 20526607 |
| Respiratory complication, Inflammation, Actual blood loss, Edema | Altered Intercellular Communication | Third, minimally invasive esophagectomy might reduce respiratory complications and blood loss because this procedure reduces edema and inflammation in the lung. | 20526722 |
| Inflammation, Osteolysis | Altered Intercellular Communication | Biodegradable implants lead to problems such as cyst formation, soft-tissue inflammation, loose implant fragments or local osteolysis. | 20526849 |
| Inflammation, Primary peritoneal carcinoma, Actinomycosis | Altered Intercellular Communication | Pelvic CT and MRI were limited in their ability to differentiate inflammation, such as actinomycosis, from primary carcinoma of the peritoneum. | 20527245 |
| anti-endothelial cell antibody, Electrocardiogram: myocardial infarction (finding), Inflammation, Atherosclerosis | Altered Intercellular Communication | We report for the first time evidence that AECA are related to signs of inflammation and are increased in patients with atherosclerosis and previous myocardial infarction and with further increase with severity of disease. | 20528242 |
| Asthma, Bronchitis | Altered Intercellular Communication | Smoking has been shown to increase the lung function decline in adult asthma patients and change the composition of the bronchial inflammation. | 20528587 |
| vascular inflammations, Periodontitis, Atherosclerosis | Altered Intercellular Communication | Periodontitis is suggested to enhance the process of vascular inflammation leading to atherosclerosis. | 20528962 |
| Inflammation, Aortic Stiffness | Altered Intercellular Communication | Inflammation and the level of repetitive cyclic stress are important predictors of aortic stiffness, whereas wave reflection is predicted by acute inflammation only. | 20530296 |
| Inflammation, Infection, Impaired | Altered Intercellular Communication | Factors other than asbestos that may play a role include genetic predisposition, immune impairment, infections, radiation, dietary factors, and recurrent serosal inflammation. | 20530447 |
| Inflammation, Neoplasms | Altered Intercellular Communication | We consider that, in the presented case, inflammation and healing resulting from pericardiotomy might have had a synergistic effect with asbestos in the pathogenesis of the tumor. | 20530447 |
| Inflammation, Helicobacter pylori, Stomach Carcinoma, Gastritis, Intestinal metaplasia, Atrophic | Altered Intercellular Communication | Matched tumor/nontumor adjacent mucosa (NTAM) of 91 early gastric cancer and 148 chronic gastritis cases were evaluated for histologic characteristics (atrophy, intestinal metaplasia, chronic inflammation, polymorphonuclear infiltration, and Helicobacter pylori) by the Sydney System. | 20530692 |
| Atrophic | Altered Intercellular Communication | Histologically, NTAM have severe intestinal metaplasia/chronic inflammation and severe atrophy assessed by Sydney and OLGA staging systems. | 20530692 |
| Inflammation, Erosion lesion, Ulcer | Altered Intercellular Communication | Colonoscopy revealed ileal erosion, a longitudinal ulcer in the ascending colon but only mild rectal inflammation. | 20530926 |
| Cancer-related fatigue, Inflammation | Altered Intercellular Communication | These findings support the key role of CRF and fatness on low-grade inflammation, as well as the possible indirect role of habitual PA through CRF and body fat in adolescents. | 20531354 |
| Inflammation, Respiratory physiology | Altered Intercellular Communication | Inflammation is increasingly linked to loss of lung function and evidence suggests that consumption of dietary fat exacerbates inflammation. | 20531437 |
| Inflammation, Endophthalmitis, CTCAE, Ulceration, CTCAE, Perforation (observation) | Altered Intercellular Communication | Despite intensive treatment with topical and oral antifungal agents, scleral inflammation and ulceration progressed, and scleral perforation and endophthalmitis developed. | 20532146 |
| Inflammation | Altered Intercellular Communication | However, scleral and intraocular inflammation progressed, and the eye was enucleated. | 20532146 |
| Inflammation, Fatty degeneration | Altered Intercellular Communication | Mild to severe steatosis was noted in 7 patients (19%) and aspecific portal inflammation in 11 patients (30%). | 20532569 |
| Neurodegenerative Disorders, Neurogenic Inflammation, Inflammation, Parkinson Disease, palladium | Altered Intercellular Communication | Although neuroinflammation is known to play an important role in the pathogeneses of neurodegenerative diseases, few studies have been conducted on the association between Parkinson's disease (PD) and high-sensitivity C-reactive protein (hs-CRP), which is the most studied biomarker of systemic inflammation. | 20532580 |
| Pain Distress Question, Inflammation, Hypereosinophilia | Altered Intercellular Communication | One month later, he reported improvements in general health, pain, motion, joint mobility, and skin induration associated with normalization of both hypereosinophilia and biologic inflammation. | 20532934 |
| Intraocular inflammation, Eye Neoplasms, Disease, Uveitis | Altered Intercellular Communication | This inflammatory condition belongs to the uveitis masquerade syndromes, which comprise a group of various ocular diseases such as chronic intraocular inflammation and ocular tumors. | 20533043 |
| Intraocular inflammation, Eye Neoplasms, Disease, Uveitis | Altered Intercellular Communication | This inflammatory condition belongs to the uveitis masquerade syndromes, which comprise a group of various ocular diseases such as chronic intraocular inflammation and ocular tumors. | 20533043 |
| Pain Distress Question, Inflammation | Altered Intercellular Communication | A 50 g force could effectively induce tooth movement similar to 150 g with less pain and less inflammation. | 20534713 |
| Sepsis, Inflammation, Bacterial Infections | Altered Intercellular Communication | Procalcitonin, a well-known biomarker of sepsis and bacterial infections, is produced by adipose tissue and has potential as a marker for chronic low-grade inflammation. | 20534760 |
| Corneal edema | Altered Intercellular Communication | Eighteen eyes had corneal edema and 36 eyes had anterior chamber inflammation. | 20534920 |
| Alzheimers Disease | Altered Intercellular Communication | Alzheimer disease also involves glutamatergic neurotransmitter system disturbances. | 20535038 |
| Airway structure, Asthma | Altered Intercellular Communication | Measuring fractional exhaled nitric oxide (FeNO) provides an indication of airway inflammation and is used as an inflammatory marker for asthma management. | 20536283 |
| Refractory anemias, Rheumatoid Arthritis, Autoimmune Diseases, Inflammation | Altered Intercellular Communication | Rheumatoid arthritis (RA) is a systemic autoimmune disease that is characterized by chronic synovial inflammation. | 20536605 |
| Tissue damage | Altered Intercellular Communication | In contrast, tissue damage during the third postnatal week failed to significantly alter spontaneous excitatory or inhibitory synaptic transmission in the SDH. | 20536930 |
| Inflammation | Altered Intercellular Communication | The increase in CRP levels before onset of AF may support the hypothesis that systemic inflammation is an important trigger for AF. | 20537138 |
| Diabetic Nephropathy, Inflammation | Altered Intercellular Communication | Low-energy diet applied in diabetic nephropathy may decrease serum resistin levels and inflammation. | 20537918 |
| Inflammation, Cyclophosphamide/Vincristine/Dacarbazine Regimen, Cardiovascular Diseases | Altered Intercellular Communication | Inflammation plays an important role in cardiovascular disease (CVD). | 20538029 |
| Peripheral Vascular Diseases, Inflammation | Altered Intercellular Communication | Lipoprotein(a), inflammation, and peripheral arterial disease in a community-based sample of older men and women (the InCHIANTI study). | 20538138 |
| Inflammation, Dental Plaque, Ischemic stroke | Altered Intercellular Communication | Systemic and intraplaque mediators of inflammation are increased in patients symptomatic for ischemic stroke. | 20538699 |
| Ischemic stroke | Altered Intercellular Communication | Thus, we investigated the possible role of systemic and intraplaque inflammation in patients asymptomatic versus symptomatic for ischemic stroke. | 20538699 |
| Inflammation, Cardiovascular Diseases, Hyperuricemia, Kidney Diseases, Hypertension, CTCAE | Altered Intercellular Communication | Hyperuricemia is associated with hypertension, inflammation, renal disease progression, and cardiovascular disease. | 20538833 |
| palladium, Inflammation, Overhydrated | Altered Intercellular Communication | Peritoneal dialysis (PD) patients may be overhydrated especially when inflammation is present. | 20538836 |
| Inflammation, Osage language, craniofacial development, Obesity, Sleep Apnea, Obstructive | Altered Intercellular Communication | Obstructive sleep apnea (OSA) is hypothesized to be influenced by genes within pathways involved with obesity, craniofacial development, inflammation, and ventilatory control. | 20538960 |
| Uveal melanoma, Inflammation, Humor | Altered Intercellular Communication | This study was conducted to determine whether the aqueous humor (AqH) from eyes with uveal melanoma contains inflammatory cytokines and whether their presence is associated with inflammation. | 20538984 |
| Inflammation, Metabolic Syndrome X, ETV3 wt Allele | Altered Intercellular Communication | Aberrations in apolipoprotein (apo) metabolism and increased systemic inflammation associate with the metabolic syndrome (MetS) and may contribute to its atherogenicity. | 20539018 |
| Inflammation | Altered Intercellular Communication | In conclusion, H. pylori-induced miR-146a plays a potential role in a negative feedback loop to modulate the inflammation by targeting IRAK1 and TRAF6. | 20542134 |
| Inflammation, Observation Method - Coagulation | Altered Intercellular Communication | These findings underscore the close interaction between inflammation and coagulation and provide evidence that these simple laboratory tests should be routinely considered during the early evaluation of the infected patient. | 20542399 |
| Inflammation, Dental Plaque, atherosclerotic | Altered Intercellular Communication | Eicosapentaenoic acid (EPA) from highly concentrated n-3 fatty acid ethyl esters is incorporated into advanced atherosclerotic plaques and higher plaque EPA is associated with decreased plaque inflammation and increased stability. | 20542512 |
| Inflammation, atherosclerotic | Altered Intercellular Communication | To examine n-3 polyunsaturated fatty acid (PUFA) incorporation into atherosclerotic plaques and the association with plaque inflammation and stability. | 20542512 |
| Inflammation, Dental Plaque | Altered Intercellular Communication | A higher plaque EPA content is associated with a reduced number of foam cells and T cells, less inflammation and increased stability. | 20542512 |
| Airway structure, Influenza virus | Altered Intercellular Communication | l-carbocisteine may reduce airway inflammation in influenza virus infection. | 20543005 |
| Dental Plaque | Altered Intercellular Communication | Identification of carotid plaque inflammation with PET can be performed 1 h after FDG injection using SUVmax for plaque FDG uptake quantification. | 20543757 |
| Communicable Diseases, Inflammation, Dental Plaque, Atherosclerosis | Altered Intercellular Communication | Since lipoprotein-associated phospholipase A2 (Lp-PLA(2)) mediates inflammation in atherosclerosis, we hypothesized that serum Lp-PLA(2) mass and activity levels and plaque Lp-PLA(2) may be influenced by plaque C. pneumoniae infection. | 20543948 |
| Inflammation, Dental Plaque, Atherosclerosis | Altered Intercellular Communication | The significant association of plaque Lp-PLA(2) with plaque macrophages and C. pneumoniae suggests an interactive role in accelerating inflammation in atherosclerosis. | 20543948 |
| Pyelonephritis | Altered Intercellular Communication | Xanthogranulomatous pyelonephritis (XGP) is a chronic inflammatory condition of the kidneys. | 20544282 |
| Inflammation, Fever, CTCAE, Urticaria, Arthralgia, Gammopathy, Bone pain | Altered Intercellular Communication | Schnitzler syndrome is a rare disorder characterized by monoclonal IgM gammopathy, urticaria, recurrent fever, evidence of inflammation, bone pain, and arthralgia. | 20544653 |
| Inflammation, Osteopenia | Altered Intercellular Communication | A moderate correlation between TWEAK/Fn14 expression and inflammation and bone loss, but not pocket depth, was noted. | 20546112 |
| Inflammation, Periodontitis | Altered Intercellular Communication | Our data support the concept that TWEAK/Fn14 signaling is an additional player in the pathogenesis of periodontitis and adds to the increasing number of cytokine networks involved in periodontal inflammation. | 20546112 |
| Inflammation, Respiratory Aspiration of Gastric Contents | Altered Intercellular Communication | We also wished to determine whether an acidic environment in the lung influences pulmonary function and DL(CO), and whether microaspiration of gastric contents directly influences non-specific inflammation in the lung. | 20546193 |
| Carcinogenic Chlorinated Hydrocarbon, Fibrosis Assessment | Altered Intercellular Communication | Age, serum total cholesterol, and hepatic necro-inflammation have important associations with severity of hepatic fibrosis in CHC patients. | 20546452 |
| Inflammation, Arteriopathic disease | Altered Intercellular Communication | Systemic inflammation may be a common factor behind such symptoms and the subsequent development of arterial disease. | 20549275 |
| ARCN1 gene, Airway structure | Altered Intercellular Communication | The percentage of neutrophils in sputum are increased in COPD patients, and may therefore be a biomarker of airway inflammation. | 20550701 |
| Inflammation, Pulmonary Emphysema | Altered Intercellular Communication | We studied the relationships between sputum neutrophils and FEV1, health status, exacerbation rates, systemic inflammation and emphysema, and long term variability at 1 year. | 20550701 |
| Inflammation, Pulmonary Emphysema | Altered Intercellular Communication | Sputum neutrophil measurements were dissociated from exacerbation rates, emphysema and systemic inflammation. | 20550701 |
| Vertigo, hearing impairment, Inflammatory abnormality of the eye, Have Dizziness, Nausea | Altered Intercellular Communication | The administration of a combined immunosuppressive treatment resolved ocular inflammation, dizziness, nausea, and vertigo but gave little results in controlling progressive hearing loss. | 20550723 |
| Inflammation, Neoplasms | Altered Intercellular Communication | Current models of oncogenesis incorporate the contributions of chronic inflammation and aging to the patterns of tumor formation. | 20551058 |
| Inflammation, Scleroderma , Systemic Scleroderma | Altered Intercellular Communication | Characteristics of joint involvement and relationships with systemic inflammation in systemic sclerosis: results from the EULAR Scleroderma Trial and Research Group (EUSTAR) database. | 20551097 |
| Inflammation, Contracture of joint, Synovitis | Altered Intercellular Communication | Our data also show that synovitis, joint contracture, and tendon friction rubs are associated with a more severe disease and with systemic inflammation. | 20551097 |
| millicurie, Data types - Address | Altered Intercellular Communication | As most of these amino acids and metabolic compounds are functionally important for brain-specific metabolic processes, neurotransmitter pathways or compensatory mechanisms, our findings might reflect these changes occurring within the brain of patients with MCI and those who developed manifest AD. | 20551690 |
| Crohn Disease, Inflammation | Altered Intercellular Communication | Outcomes included acute pouchitis (antibiotic responsive), chronic pouchitis (antibiotic dependent or refractory), or de novo Crohn's disease (small inflammation above the pouch inlet or pouch fistula). | 20551749 |
| Inflammation, Necrosis | Altered Intercellular Communication | Cystic duct clips or hemostatic clips migrating into the common bile duct after biliary surgery, although rare are well recognized and assumed to relate to improper clip application, bile leak (usually subclinical), inflammation, and subsequent necrosis, allowing the clips to erode directly into the common bile duct. | 20551787 |
| Inflammation, Weight decreased | Altered Intercellular Communication | The mean concentrations of inflammation parameters decreased during a period of weight loss and dietary intervention. | 20551965 |
| Orbital Pseudotumor | Altered Intercellular Communication | Digital infrared thermal imaging (DITI) detects local temperature and may reflect the degree of orbital inflammation. | 20553230 |
| Inflammation | Altered Intercellular Communication | Basal temperature of the eyes measured by DITI was an objective indicator of inflammation of GO. | 20553230 |
| Obesity | Altered Intercellular Communication | Obesity is associated with increased hs-CRP levels in 6-12 year-old children, a finding that supports the inflammation-obesity hypothesis at an early stage of life. | 20554094 |
| Inflammation, Atherosclerosis | Altered Intercellular Communication | Occult impaired glucose regulation in patients with atherosclerosis is associated to the number of affected vascular districts and inflammation. | 20554281 |
| square decimeter, Cardiovascular Diseases | Altered Intercellular Communication | The role of inflammatory adipokines has clear mechanistic effects in the promotion of both DM2 and cardiovascular diseases (CVDs), but it is unknown to what extent atherosclerosis-related inflammation might promote defects of glucose metabolism. | 20554281 |
| Pain Distress Question, Inflammation, Gastrointestinal Pain, CTCAE, Fever, CTCAE, Bothered by Vomiting, Diarrhea, Nasopharyngitis, Edema, Joint swelling, Fatigue | Altered Intercellular Communication | These were clustered into five groups: fever; musculoskeletal (pain and joint swelling); gastrointestinal (abdominal pain, vomiting, diarrhea); eye inflammation; and general (including fatigue, nasopharyngitis, edema). | 20554708 |
| Inflammation, Primary malignant neoplasm, Communicable Diseases, Hyperglycemia, Diabetes Mellitus | Altered Intercellular Communication | Do hyperglycemia and diabetes affect the incidence of false-negative 18F-FDG PET/CT studies in patients evaluated for infection or inflammation and cancer? | 20554733 |
| Communicable Diseases, Inflammation, Malignant Neoplasms | Altered Intercellular Communication | (18)F-FDG PET/CT studies of 123 consecutive patients investigated for suspected infection or inflammation and 320 patients evaluated for malignancy were retrospectively analyzed. | 20554733 |
| Communicable Diseases, Inflammation | Altered Intercellular Communication | In the infection or inflammation group, 19 of 123 patients (15%) had serum glucose levels greater than 180 mg/dL and 43 of 123 (35%) had DM. | 20554733 |
| Communicable Diseases, Inflammation | Altered Intercellular Communication | Neither glucose levels nor DM affects the detection rate of infection or inflammation with (18)F-FDG PET/CT. | 20554733 |
| Inflammation | Altered Intercellular Communication | SUVmax assessment may allow an objective, reliable indication of the grade and severity of inflammation activity in abnormal segments of the bowel detected by CT enterography. | 20554741 |
| Inflammation | Altered Intercellular Communication | Downregulated genes reflected several biological pathways such as inflammation, angiogenesis, B- and T-cell activation. | 20555356 |
| Proteinuria, Inflammation, Hematuria, CTCAE, Anemia | Altered Intercellular Communication | On admission, his blood pressure was 166/92 mmHg, and laboratory findings showed signs of inflammation, anemia, proteinuria, and hematuria. | 20556459 |
| Inflammation, bone destruction, Neoplasms, Infection, Fracture | Altered Intercellular Communication | Active pathological bone destruction in humans often occurs in locations where oxygen tension (pO(2)) is likely to be low, for example, at the sites of tumours, inflammation, infections and fractures, or the poorly vascularized yellow fatty marrow of the elderly. | 20556743 |
| Inflammation, Saint Lucia | Altered Intercellular Communication | Inflammation was diagnosed in 70.7% of open cholecystectomy (OC) and 42.1% of LC patients. | 20557412 |
| Autoimmune Diseases, Primary Biliary Cholangitis, Hepatitis | Altered Intercellular Communication | Primary biliary cirrhosis (PBC) is an organ-specific autoimmune disease of still unidentified genetic etiology that is characterized by chronic inflammation of the liver. | 20557968 |
| Macroprolactinemia, Hyperprolactinemia | Altered Intercellular Communication | His hormonal evaluation indicated a marked hyperprolactinemia mainly due to macroprolactinemia (total prolactin, 514 ng/ml; reference range, 1.6-10.7 ng/ml; macroprolactin 436 ng/ml, monomer prolactin 78.2 ng/ml). | 20558354 |
| Heart Ventricle, Sleep Apnea, Obstructive, Inflammation, Osage language | Altered Intercellular Communication | N-terminal pro-B-type natriuretic peptide (NT-proBNP), a marker of ventricular strain, and C-reactive protein (CRP), a marker of inflammation, are reportedly elevated in school-aged children with obstructive sleep apnea (OSA). | 20558551 |
| Inflammation, Hypoxemia, Osage language | Altered Intercellular Communication | Echocardiographic parameters suggesting increased pulmonary pressure in young children with OSA are related to nocturnal hypoxemia and systemic inflammation, which also decrease following therapy. | 20558551 |
| Inflammation | Altered Intercellular Communication | Magnetic resonance imaging of this patient's brain suggested inflammation of the bilateral basal ganglia and amygdalae. | 20558943 |
| Airway structure, Asthma | Altered Intercellular Communication | Exposure to particulate matter (PM) outdoors can induce airway inflammation and exacerbation of asthma in adults. | 20559007 |
| Inflammation, Neoplasms | Altered Intercellular Communication | Several case reports have discussed the difficulty in differentiating junctional pseudomelanocytic nests as a result of lichenoid inflammation from a true melanocytic neoplasm. | 20559116 |
| Inflammation, Intraocular inflammation | Altered Intercellular Communication | In most cases of sterile intraocular inflammation after IVB, visual acuity returned to baseline, and intraocular inflammation rarely recurred with repeat IVB or intravitreal ranibizumab. | 20559156 |
| Inflammation, Carcinogenesis | Altered Intercellular Communication | Inflammation is postulated to play an important role in ovarian carcinogenesis. | 20559705 |
| Inflammation, Myocarditis, CTCAE 5.0 | Altered Intercellular Communication | The clinical diagnosis of bacterial-induced myocarditis was confirmed by specific radiological findings of inflammation using cardiac magnetic resonance imaging. | 20559889 |
| Inflammation, curcumin, Observation Method - Coagulation | Altered Intercellular Communication | Immune-mediated inflammation and coagulation are strictly linked, and coagulation activation has been described in CU patients as shown by the elevation of plasma prothrombin fragment F1+2 and, in severe cases, of d-dimer as well. | 20561123 |
| Inflammation, Primary malignant neoplasm, Cardiovascular Diseases, Cyclophosphamide/Vincristine/Dacarbazine Regimen, Diabetes Mellitus, Diabetes Mellitus, Non-Insulin-Dependent | Altered Intercellular Communication | Low-grade inflammation is thought to contribute to the development of cardiovascular disease (CVD), type-2 diabetes mellitus (T2D), cancer and mortality. | 20561148 |
| Inflammation | Altered Intercellular Communication | Biomarkers of inflammation may aid in risk prediction and enable early intervention and prevention of disease. | 20561148 |
| Inflammation, Deep thrombophlebitis | Altered Intercellular Communication | It is concluded that the DVT and inflammation are closely related, increased level of plasma CRP may be a predictor of DVT. | 20561444 |
| Inflammation, Observation Method - Coagulation, Deep thrombophlebitis | Altered Intercellular Communication | Interaction between inflammation and coagulation promote the incidence of DVT, which may be one of DVT pathogenesis. | 20561444 |
| Pain Distress Question, Inflammation, Edema | Altered Intercellular Communication | The VCSS 2 and 3 for pain, oedema and inflammation were found in 22%, 26% and 0% of C6 legs. | 20561800 |
| Disorder of vein, Pain Distress Question, Inflammation, Edema | Altered Intercellular Communication | Visible varicose veins, pain, oedema and inflammation were uncommon and most patients could maintain their usual activities despite advanced venous disease. | 20561800 |
| Cessation of life, Inflammation | Altered Intercellular Communication | PARP-1 is involved in the regulation of genomic integrity, transcription, inflammation, and cell death. | 20561897 |
| Inflammation, Hepatitis, Cardiomyopathies, Pneumonitis, CTCAE, kyphosis, Anemia, Dermatitis, Kidney Diseases | Altered Intercellular Communication | Here, we show that hPARP-1 mice exhibit impaired survival rates accompanied by reduced hair growth and premature development of several inflammation and age-associated pathologies, such as adiposity, kyphosis, nephropathy, dermatitis, pneumonitis, cardiomyopathy, hepatitis, and anemia. | 20561897 |
| allergic inflammation | Altered Intercellular Communication | Recent studies have associated osteopontin (OPN) with allergic inflammation; however, its role in human asthma remains unclear. | 20562127 |
| Traumatic injury, Kidney Diseases | Altered Intercellular Communication | We performed a secondary analysis of the "Inflammation and the Host Response to Injury" (Glue Grant) database to include adult blunt trauma patients without history of kidney disease. | 20562612 |
| Calcified (qualifier), Atheroma, Inflammation | Altered Intercellular Communication | Calcifications were stable over time, but 18F-FDG uptake changed in more than half of the patients, supporting the postulate that inflammation in atheroma is a waxing and waning inflammatory process. | 20562727 |
| Inflammation | Altered Intercellular Communication | Systemic inflammation caused by chronic periodontite in patients victims of acute ischemic heart attack. | 20563468 |
| Inflammation, Prostatic Intraepithelial Neoplasias | Altered Intercellular Communication | While Gleason scores remained relatively stable over time, reporting of prostate intraepithelial neoplasia (PIN) and inflammation increased. | 20564087 |
| Granulomatous inflammation, Necrosis | Altered Intercellular Communication | Seventy-two percent of the cases showed necrosis, often accompanied by acute, chronic, or granulomatous inflammation. | 20564422 |
| Inflammation, Fracture, Difficulty walking | Altered Intercellular Communication | The approach is applied to a cohort of elderly female hip fracture patients to estimate the prevalence of walking disability over time as a function of body composition, inflammation, and age. | 20564729 |
| Inflammation, Thrombosis | Altered Intercellular Communication | Isolated superior ophthalmic vein (SOV) thrombosis is a rare condition usually related to inflammation of the orbit or paranasal sinuses. | 20565317 |
| Inflammation, Fibrosis Assessment, Fatty degeneration | Altered Intercellular Communication | Our results show that donor histology can affect disease recurrence, especially the grade of inflammation, fibrosis, and fatty degeneration. | 20565366 |
| Stomatitis, Stomach Carcinoma, Infection caused by Helicobacter pylori | Altered Intercellular Communication | Gastric cancer can progress from a chronic inflammation of the gastric mucosa resulting from Helicobacter pylori infection that activates the inflammatory response of the host. | 20565800 |
| Intraocular inflammation, Complication Aspects | Altered Intercellular Communication | From 70-80% of positive untreated HIV patients develop ocular complications, with intraocular inflammation in more than half of them. | 20566167 |
| Intraocular inflammation, Opportunistic Infections, Neoplasms | Altered Intercellular Communication | Intraocular inflammation can be associated with opportunistic infections, tumours and as in our case, secondary to the HIV. | 20566167 |
| Inflammation, Chronic Obstructive Airway Disease | Altered Intercellular Communication | Abdominal fat mass contributes to the systemic inflammation in chronic obstructive pulmonary disease. | 20566396 |
| ARCN1 gene, Inflammation | Altered Intercellular Communication | The contribution of abdominal fat mass to the systemic inflammation often present in COPD has not been examined yet. | 20566396 |
| ARCN1 gene, Inflammation | Altered Intercellular Communication | The aim of the present study was to investigate if abdominal fat mass contributes to the systemic inflammation in patients with moderate to severe COPD. | 20566396 |
| ARCN1 gene, Inflammation | Altered Intercellular Communication | Abdominal fat mass contributes to the systemic inflammation in COPD. | 20566396 |
| Ischemia, Hemorrhage, Adipose Tissue Atrophy, Necrosis, Fibrosis Assessment, Myositis, Infarction, Diabetic Cardiomyopathies | Altered Intercellular Communication | Diabetic myopathy encompasses a spectrum of diseases, including muscle inflammation, ischemia, hemorrhage, infarction, necrosis, fibrosis, and fatty atrophy. | 20566817 |
| Granulomatous inflammation | Altered Intercellular Communication | While granulomatous inflammation was a rare observation in North American cases, it was seen in the majority of cases worldwide. | 20567913 |
| Granulomatous inflammation | Altered Intercellular Communication | Patients with A. flavus were younger, demonstrated granulomatous inflammation, and pursued an indolent, clinically responsive course. | 20567913 |
| Airway structure, Asthma | Altered Intercellular Communication | Severe asthma occurs in a heterogeneous group of patients in whom symptoms and airway inflammation persist despite maximal antiasthma treatment. | 20568377 |
| Inflammation, Metabolic Syndrome X, ETV3 wt Allele | Altered Intercellular Communication | Subjects with the metabolic syndrome (MetS) have enhanced oxidative stress and inflammation. | 20569506 |
| Inflammation, ETV3 wt Allele | Altered Intercellular Communication | In conclusion, a 12-week dietary fat modification did not affect the investigated markers of oxidative stress and inflammation among subjects with the MetS in the LIPGENE study. | 20569506 |
| Communicable Diseases, Inflammation, Malignant Neoplasms | Altered Intercellular Communication | Although it grows slowly and usually without symptoms, it may require excision because of inflammation, secondary infection, or, in rare cases, malignancy developing within the cyst. | 20569540 |
| Inflammation, Malignant Neoplasms, Uterine Corpus Sarcoma | Altered Intercellular Communication | Since malignancy is known to be associated with systemic inflammation which leads to hematological alteration, we compared the efficacy for the preoperative diagnosis of uterine sarcomas between the neutrophil to lymphocyte ratio (NLR) and serum CA-125 levels using a case-match comparison. | 20570475 |
| Squamous cell carcinoma of esophagus | Altered Intercellular Communication | Inflammation-based prognostic score and number of lymph node metastases are independent prognostic factors in esophageal squamous cell carcinoma. | 20571271 |
| Inflammation | Altered Intercellular Communication | The growing body of evidence linking inflammation and frailty in older people, an association that seems consistent across different frailty definitions, is therefore of great interest to research gerontologists. | 20571864 |
| Fibrosis Assessment, Hepatic inflammation | Altered Intercellular Communication | The extent of hepatic inflammation and fibrosis was evaluated in these patients by examining liver biopsy specimens. | 20572087 |
| Fibrosis Assessment, Hepatic inflammation | Altered Intercellular Communication | All 10 patients with significant hepatic inflammation and fibrosis were male and older than 25 years. | 20572087 |
| Cessation of life, Inflammation | Altered Intercellular Communication | Cox proportional hazards ratios were calculated both for death from diseases in which inflammation or oxidative stress was a predominant contributor and for cardiovascular mortality. | 20573797 |
| Inflammation, Herpes zoster disease, Exanthema | Altered Intercellular Communication | This is the first report defining the nature of the immune response in ganglia following herpes zoster and provides evidence for persistence of non-latency-associated viral antigen and inflammation beyond rash resolution. | 20573825 |
| Retinitis | Altered Intercellular Communication | The origin of the SDPs observable in SD-OCT is unknown, but they may represent migrating RPE cells or leukocytes, indicating a certain status of retinal inflammation. | 20574019 |
| Data types - Address | Altered Intercellular Communication | Although recent evidence suggests alterations in 5-HT neurotransmission in AD, it is not clear how hippocampal 5-HT innervation is modified. | 20576032 |
| Cystic Lesion, Sialorrhea | Altered Intercellular Communication | Some cystic lesions may be functioning and should therefore be screened for hormonal hypersecretion. | 20576282 |
| Inflammation, Hepatitis C | Altered Intercellular Communication | Common variation of IL28 affects gamma-GTP levels and inflammation of the liver in chronically infected hepatitis C virus patients. | 20576307 |
| Inflammation, Fibrosis Assessment | Altered Intercellular Communication | We also found that inflammation activity and fibrosis of the liver were significantly more severe in patients homozygous for the IL28 major allele (p=0.025 and 0.036, respectively). | 20576307 |
| Hepatitis C, Liver diseases | Altered Intercellular Communication | These results suggest that different cytokine profiles induced by the IL28 polymorphism resulted in different biochemical and inflammatory conditions during chronic HCV infection and contribute to the progression of liver diseases. | 20576307 |
| Idiopathic disease, Giant Cell Arteritis, Inflammation, Takayasu Arteritis | Altered Intercellular Communication | Giant cell arteritis, Takayasu arteritis, and Horton disease are rare, idiopathic diseases that cause chronic inflammation and obliteration of large arteries, mainly the aorta and its major branches. | 20576654 |
| Inflammation | Altered Intercellular Communication | We aimed to analyze whether markers of systemic inflammation can predict response to antibiotics in AECOPD. | 20576731 |
| Scleritis | Altered Intercellular Communication | Clinical records of 83 patients with scleritis who presented between 1998 and 2008 to the Ocular Inflammation Service of the Kyorin Eye Center, Tokyo, were reviewed. | 20576778 |
| Inflammation, Carcinogenesis | Altered Intercellular Communication | Variation in genes contributing to the host immune response may mediate the relationship between inflammation and prostate carcinogenesis. | 20576793 |
| Inflammation, Prostate carcinoma | Altered Intercellular Communication | The results of this study support a link between RNASEL and prostate cancer and suggest that the association may be mediated through inflammation. | 20576793 |
| Inflammation | Altered Intercellular Communication | The chronic inflammation is most probably owing to the chronic topical treatment of the patients and seems to be a significant risk factor for DS surgery failure. | 20577105 |
| Inflammation, Albuminuria, atherosclerotic | Altered Intercellular Communication | Increased MA in TT homozygous women might be explained by other mechanisms of albuminuria or inflammation than the atherosclerotic process. | 20577224 |
| Inflammation | Altered Intercellular Communication | Extraskeletal bone formation associated with inflammation preceding the osseous conversion usually begins in the first decade, predominantly in the head, neck, and shoulders. | 20577760 |
| Inflammation, Neoplasm Metastasis | Altered Intercellular Communication | Heparanase activity plays a decisive role in biological processes associated with remodeling of the extracellular matrix (e.g., cancer metastasis, angiogenesis, and inflammation). | 20578081 |
| Inflammation, Acute Coronary Syndrome, GDC AJCC Clinical Stage Terminology | Altered Intercellular Communication | Inflammation has been shown to be a major component in the pathophysiology of acute coronary syndrome (ACS). | 20579652 |
| Inflammation, atherosclerotic | Altered Intercellular Communication | Longitudinal studies are needed to assess whether this increase is due to inflammation or a higher atherosclerotic burden. | 20579652 |
| Inflammation | Altered Intercellular Communication | Recently, immune response and inflammation were suggested to play certain roles in the development and complications of T2DM. | 20580039 |
| Minimal Disseminated Disease, Unipolar Depression, Alcoholic Intoxication, Chronic | Altered Intercellular Communication | Alteration of glutamatergic neurotransmission in the prefrontal cortex (PFC) may contribute to the pathophysiology of alcoholism and major depressive disorder (MDD). | 20580095 |
| Inflammation, Non-alcoholic Fatty Liver Disease | Altered Intercellular Communication | Relationship between portal chronic inflammation and disease severity in paediatric non-alcoholic fatty liver disease. | 20580331 |
| Fibrosis, Liver, Inflammation, Non-alcoholic Fatty Liver Disease | Altered Intercellular Communication | The non-alcoholic steato-hepatitis Clinical Research Network has recently shown that portal chronic inflammation is associated with liver fibrosis in American children with non-alcoholic fatty liver disease. | 20580331 |
| Non-alcoholic Fatty Liver Disease | Altered Intercellular Communication | We tested whether the portal chronic inflammation-fibrosis association was present in a series of Italian children with non-alcoholic fatty liver disease. | 20580331 |
| Nonalcoholic Steatohepatitis, Inflammation, Non-alcoholic Fatty Liver Disease | Altered Intercellular Communication | Non-alcoholic fatty liver disease and portal chronic inflammation were diagnosed using the non-alcoholic steato-hepatitis Clinical Research Network criteria. | 20580331 |
| Nonalcoholic Steatohepatitis, Inflammation | Altered Intercellular Communication | Two children had no portal chronic inflammation, 84 had mild and 58 more than mild portal chronic inflammation according to the non-alcoholic steato-hepatitis Clinical Research Network criteria. | 20580331 |
| Inflammation | Altered Intercellular Communication | Children with no or mild portal chronic inflammation had the same clinical features of those with more than mild portal chronic inflammation except for insulin resistance, which was greater. | 20580331 |
| Inflammation, Fibrosis Assessment, Fatty degeneration | Altered Intercellular Communication | There was no association between steatosis, lobular inflammation, ballooning, fibrosis and portal chronic inflammation. | 20580331 |
| Inflammation, Non-alcoholic Fatty Liver Disease | Altered Intercellular Communication | We were not able to confirm the existence of a clinico-pathological association between portal chronic inflammation and disease severity in a series of Italian children with non-alcoholic fatty liver disease. | 20580331 |
| Inflammation, Arthritis | Altered Intercellular Communication | We have investigated associations between angiogenesis, inflammation and neurovascular growth factor expression at the osteochondral junction in human arthritis. | 20581375 |
| Subject Disease Milestones Domain, Inflammation, Trigone of bladder, Squamous metaplasia | Altered Intercellular Communication | Two, partly overlapped, pathologic patterns prevailed: (a) nonkeratinizing squamous metaplasia (SM) found in 64% of the patients, including 2 of 4 men; (b) mucosal inflammation of the bladder base/trigone that extended-especially among male patients-to the proximal urethra (64% of the patients). | 20581654 |
| Inflammation, Adenocarcinoma of colon | Altered Intercellular Communication | On histopathologic examination, the patient had nonspecific, active, chronic inflammation of the ileal mucosa, consistent with backwash ileitis, and colonic adenocarcinoma. | 20581781 |
| Inflammatory disease of mucous membrane | Altered Intercellular Communication | Despite additional treatment with leukocytapheresis, the backwash ileitis progressed, with increased severity of mucosal inflammation and extensive erosions, 20 cm proximal to the primarily affected site of the ileum on repeat colonoscopy 2 months later. | 20581781 |
| Inflammation, Fibrosis Assessment | Altered Intercellular Communication | The following histological features were associated with each other: prominent inflammation, anastomosing sheets, absence of fibrosis, absence of infiltrative margin and absence of gland formation. | 20581807 |
| Inflammation, Neoplasms | Altered Intercellular Communication | Prominent inflammation and anastomosing sheets in at least 30% of the tumour were associated with a better prognosis on univariate analysis. | 20581807 |
| Inflammation, Autoimmune reaction | Altered Intercellular Communication | Th17 cells play an important role in inflammation in human autoimmune arthritides, both at the onset and in established disease. | 20583102 |
| Inflammation, Fournier Gangrene | Altered Intercellular Communication | We report a 58-year-old man with rapidly progressive, gas-producing, necrotizing inflammation in the retroperitoneum, complicated with genital involvement resembling Fournier gangrene. | 20583955 |
| ACSM3 gene, Inflammation, Cerebrovascular accident | Altered Intercellular Communication | Brain parenchyma is generally not affected by the disease; however, histological investigation suggested that inflammation of the dura caused damage to superior hypophyseal artery resulting in SAH and apoplexy in the anterior lobe of the pituitary gland. | 20585819 |
| Bacteremia, Inflammation, Fever, CTCAE | Altered Intercellular Communication | Six patients had a fever, nine had inflammation at the hemodialysis access site, and six of them had concomitant bacteremia. | 20585966 |
| palladium | Altered Intercellular Communication | Our results support the hypothesis that serotonergic neurotransmission is decreased in untreated PD and suggest that a low serotonergic activity may be related to the dopamine pathology in PD. | 20586535 |
| Inflammation, Lacrimation | Altered Intercellular Communication | One case of membrane tearing resulted from previous inflammation in the maxillary sinus, and the other case of membrane tearing was caused by application of excessive hydraulic pressure. | 20586782 |
| Gastrointestinal inflammation | Altered Intercellular Communication | However, the relationship between intestinal inflammation and miRNA expression remains unclear. | 20586854 |
| Gastrointestinal inflammation, Ulcerative Colitis | Altered Intercellular Communication | Upregulated miRNA may be responsible for the development of intestinal inflammation in UC. | 20586854 |
| Fibrosis, Liver, Fibrosis Assessment, Hepatitis | Altered Intercellular Communication | Analyze the age, sex, grade of liver inflammation and stage of liver fibrosis among patients with chronic HBV carriers (n = 58) and non-active HBsAg carriers (n = 32), and compare the grade of liver inflammation and stage of liver fibrosis in different groups according to age, ALT levels and with/without HBeAg. | 20587313 |
| Fibrosis, Liver, Fibrosis Assessment, Hepatitis | Altered Intercellular Communication | (3) As to the grade of liver inflammation and the stage of liver fibrosis, significant differences existed between the groups with higher level of serum ALT (20-40 U/L) and lower level ( is less than or equal to 20 U/L) (Chi-square = 7.827, P = 0.008; Chi-square = 14.303, P = 0.001), and similar results also existed between elder group (more than 40) and younger group (is less than or equal to 40) (Chi-square = 10.949, P = 0.001; Chi-square = 21.271, P less than 0.01); (4) Among the chronic HBV carriers, significant differences existed in grade of liver inflammation between groups with HBeAg positive and negative patients (Chi-square = 10.275, P = 0.002), and the latter was more aggravated; however, there was no difference in stage of liver fibrosis between them (Chi-square test = 3.457, P = 0.178). | 20587313 |
| Inflammation, Snoring | Altered Intercellular Communication | We therefore investigated whether snoring may mediate the increased vascular risk directly through increased inflammation as indicated by HsCRP levels or if other determinants predominated in a large older Chinese population. | 20587368 |
| Inflammation, Vascular Diseases | Altered Intercellular Communication | Our results showed that snoring frequency did not have an independent effect on inflammation after adjusting for adiposity, and may thus contribute to vascular disease through alternative mechanisms. | 20587368 |
| Gastrointestinal inflammation | Altered Intercellular Communication | In 48 MDCT/MR enterography examinations, active disease was demonstrated: abscesses (n = 11), fistulas (n = 13), stenoses (n = 23) and/or intestinal inflammation (n = 38). | 20588038 |
| Inflammation, Pain Distress Question | Altered Intercellular Communication | The patient attended medical consultation after two months of inflammation and pain in her right eye. | 20589334 |
| Inflammation, Takayasu Arteritis | Altered Intercellular Communication | Takayasu's arteritis (TA) is a chronic inflammation that frequently involves the aorta and its major branches. | 20589520 |
| Interstitial inflammation | Altered Intercellular Communication | Interstitial inflammation (i1-i3) was present in all 17 biopsies. | 20590689 |
| Inflammation, Malignant Neoplasms | Altered Intercellular Communication | Further, it appears that MUC4 expression in the skin may be modulated by chronic inflammation and the presence of an adjacent cutaneous malignancy in certain cases. | 20591909 |
| Inflammation, Primary malignant neoplasm | Altered Intercellular Communication | Recent data suggest a link between chronic inflammation, angiogenesis, and the development of cancer. | 20592377 |
| Vaginitis, Bacterial Vaginosis, Inflammation, Inflammatory | Altered Intercellular Communication | Subjects were classified into 3 groups: no vaginitis if symptoms were absent and examination results was normal; common vaginitis (CV) if microscopic examination revealed yeast, bacterial vaginosis, or trichomonads; or inflammatory vaginitis (IV) if examination revealed inflammation and immature squamous cells but no pathogens. | 20592549 |
| Inflammation, Calcinosis, Atherosclerosis | Altered Intercellular Communication | Further, lipoxygenase pathway SNPs that were associated with measures of atherosclerosis were associated with markers of inflammation (CRP, ICAM-1) and calcification (MGP). | 20592751 |
| Inflammation, Carcinogenesis | Altered Intercellular Communication | Cyclooxygenase-2 (COX-2) is involved in inflammation and carcinogenesis. | 20592893 |
| Inflammation | Altered Intercellular Communication | A profile was identified in these genes that indicated a higher level of metabolism in good responding patients, which indirectly can be connected to increased inflammation. | 20593016 |
| Degenerative polyarthritis, Inflammation | Altered Intercellular Communication | The microdialysis method was applied to the human knee joint with osteoarthritis (OA) in order to reveal changes in biochemical markers of cartilage and inflammation, intraarticularly and in the synovium, in response to a single bout of mechanical joint loading. | 20594330 |
| Inflammation, Impaired cognition | Altered Intercellular Communication | Role of lipoproteins and inflammation in cognitive decline: do they interact? | 20594617 |
| Inflammation, Nasal obstruction present finding, Osage language | Altered Intercellular Communication | In conclusion, nasal obstruction of OSA patients on CPAP treatment is inflammatory in origin and the addition of heated humidification decreases nasal resistance and mucosal inflammation. | 20595158 |
| Refractory anemias | Altered Intercellular Communication | These results suggest that LILRA3 may play a role in chronic inflammatory conditions such as RA. | 20595277 |
| Inflammation, Disorder of tendon | Altered Intercellular Communication | The cellular mechanisms of tendinopathy remain unclear particularly with respect to the role of inflammation in early disease. | 20595553 |
| Coronary Artery Disease | Altered Intercellular Communication | Circulating levels of vascular and inflammation-associated microRNAs are significantly downregulated in patients with coronary artery disease. | 20595655 |
| Cushing Syndrome | Altered Intercellular Communication | She presented with signs and symptoms of hypercortisolism and hormonal testing was indicative for pituitary-dependent Cushing' s syndrome. | 20595779 |
| Inflammation, Prehypertension | Altered Intercellular Communication | Prehypertension (PreHT) and low-grade inflammation are both known to be related to the incidence of cardiovascular events. | 20596037 |
| Inflammation, CAPN5 gene | Altered Intercellular Communication | Aberrant T-cell-mediated processes may underlie ADNIV, and therapeutics directed at T cells may better manage inflammation in these patients. | 20596252 |
| Chronic liver disease, Fibrosis Assessment, Inflammation | Altered Intercellular Communication | In conclusion, we found that HCV-related HCC in the elderly occurred against a background of chronic liver disease with mild inflammation and fibrosis. | 20596605 |
| Inflammation, pseudomembranous colitis, Paralytic Ileus | Altered Intercellular Communication | The enterocytic detachment and bowel inflammation provoke C. difficile-associated diarrhoea (CDAD) sometimes developing into severe pseudomembranous colitis (PMC) and paralytic ileus. | 20597000 |
| Inflammation | Altered Intercellular Communication | As degradation of hyaluronic acid by hyaluronidase into low molecular weight hyaluronic acid (LMW-HA) is associated with inflammation and Matrix Metalloproteinase (MMP)-9 activity, we hypothesized that hyaluronic acid metabolism is increased in plaques with unstable characteristics like large lipid core, high number of macrophages, MMP-9 activity, low collagen and smooth muscle cell content. | 20597964 |
| Inflammation | Altered Intercellular Communication | Myeloperoxidase (MPO) is a hemoprotein that is released during inflammation and may lead to irreversible protein and lipid modification, increasing levels of oxidized low density lipoprotein, and promoting athrogenesis. | 20597992 |
| Inflammation, Diabetes Mellitus, Atherosclerosis | Altered Intercellular Communication | The pathogenesis of diabetes and atherosclerosis is linked through inflammation. | 20598696 |
| Nocturia, Depression, CTCAE | Altered Intercellular Communication | To assess the relationship between nocturia and depression, two inflammatory conditions that affect a significant number of men worldwide. | 20599253 |
| Inflammation, Cerebrovascular accident | Altered Intercellular Communication | Angiopoietin-2 has been reported to regulate the inflammation process, which is associated with recurrence of stroke. | 20599737 |
| Alzheimers Disease", Data types - Address, Nerve Degeneration | Altered Intercellular Communication | Oxidative stress is implicated in the pathogenesis of Alzheimer's disease (AD) causing neurodegeneration and decreased monoamine neurotransmitters. | 20600435 |
| Inflammation, Demographics Domain | Altered Intercellular Communication | To determine whether IL-18 is involved in the inflammation of DM and PM. | 20601655 |
| Inflammation, Heart failure, Anemia, hepcidin | Altered Intercellular Communication | In this group of patients with combined heart and renal failure and anaemia, increased hepcidin levels were associated with markers of iron load and not with markers of inflammation. | 20601671 |
| Inflammation, hepcidin | Altered Intercellular Communication | In our group hepcidin seems to reflect iron load and response to EPO rather than inflammation and EPO resistance. | 20601671 |
| Communicable Diseases, Inflammation, Myocarditis, CTCAE 5.0, Myocardium | Altered Intercellular Communication | Myocarditis is defined clinically as inflammation of the heart muscle, which can be caused by infectious agents, toxins or immunologic reactions. | 20601856 |
| Alzheimers Disease", Inflammation, Data types - Address, Disease | Altered Intercellular Communication | Alzheimer disease (AD) and age-related ocular diseases are characterized by inflammation and accumulation of insoluble proteins. | 20602326 |
| Unilateral, Calcinosis, Acute inflammation | Altered Intercellular Communication | The sequence of events, unilaterality, and pathologic findings suggest secondary calcification, which could have been related to severe postoperative inflammation and associated blood-aqueous barrier breakdown. | 20602329 |
| Granulomatous inflammation, Infection of kidney | Altered Intercellular Communication | XGPN is a rare type of renal infection characterised by granulomatous inflammation with giant cells and foamy histiocytes. | 20602802 |
| Venous Thromboembolism | Altered Intercellular Communication | Single nucleotide polymorphisms in inflammation-related genes are associated with venous thromboembolism. | 20603037 |
| Inflammation, vinyltriethoxysilane | Altered Intercellular Communication | Therefore, polymorphisms in genes involved in inflammation may influence susceptibility towards VTE. | 20603037 |
| Biliary Anastomotic Leakage, Acalculous Cholecystitis | Altered Intercellular Communication | Inflammation of the gallbladder caused by calculous cholecystitis, which leads to biliary leakage and erodes the right hepatic artery, could have been the cause. | 20603093 |
| Refractory anemias, Inflammation | Altered Intercellular Communication | Our results therefore provide a new insight into the IL-27-activated immunopathological mechanisms mediated by distinct intracellular signal transductions in joint inflammation of RA. | 20604932 |
| Inflammatory abnormality of the eye | Altered Intercellular Communication | To evaluate how smoking affects the time to disease quiescence and time to disease recurrence in patients with ocular inflammation. | 20606023 |
| Herpes Zoster Ophthalmicus, Inflammatory abnormality of the eye | Altered Intercellular Communication | Among 2676 patients with active ocular inflammation, smokers were more likely to have bilateral ocular disease and poorer visual acuity on presentation compared with non-smokers and previous smokers. | 20606023 |
| Low Vision, Inflammatory abnormality of the eye | Altered Intercellular Communication | Smoking was associated with an increased likelihood of bilateral ocular inflammation and reduced vision upon presentation, and an increased risk of recurrence compared with not smoking. | 20606023 |
| Inflammatory abnormality of the eye | Altered Intercellular Communication | These results suggest that patients with ocular inflammation should be counselled to stop smoking as part of routine management. | 20606023 |
| Inflammation, Acidosis, Ischemia | Altered Intercellular Communication | Systemic acidosis and subsequent inflammation after ischemia reperfusion may play an important role in the development of VT/VF. | 20606327 |
| Inflammation, Observation Method - Coagulation, Adult Glioblastoma | Altered Intercellular Communication | Circulating markers of angiogenesis, inflammation, and coagulation in patients with glioblastoma. | 20607353 |
| Inflammation, Primary malignant neoplasm | Altered Intercellular Communication | Inflammation, angiogenesis, and coagulation are linked to the development of cancer. | 20607353 |
| Inflammation, Adult Glioblastoma | Altered Intercellular Communication | All inflammation markers, F1 + 2, ETG, VEGF and sVEGFR-1, were significantly elevated in glioblastoma patients. | 20607353 |
| Inflammation | Altered Intercellular Communication | Thrombomodulin (TM) plays a role in coagulation, inflammation, and cell adhesion. | 20607726 |
| Asthmatic Airway Remodeling | Altered Intercellular Communication | Human bronchial epithelial (HBE) cells contribute to asthmatic airway inflammation by secreting cytokines, chemokines, and growth factors, including interleukin (IL)-6, IL-8 and transforming growth factor (TGF) b1, all of which are elevated in asthmatic airways. | 20607798 |
| Airway structure | Altered Intercellular Communication | Understanding the mechanism of aberrant pro-inflammatory cytokine production in asthmatic airways will allow the development of alternative ways to control airway inflammation. | 20607798 |
| Airway structure, Hypersensitivity | Altered Intercellular Communication | We speculated that IL-33 elevation is responsible for the maintenance of airway inflammation and hypersensitivity. | 20608085 |
| Inflammation, Electrocardiogram: myocardial infarction (finding) | Altered Intercellular Communication | [Complex analsis of association of inflammation genes with myocardial infarction]. | 20608170 |
| Inflammation, Electrocardiogram: myocardial infarction (finding) | Altered Intercellular Communication | Carriage frequencies of alleles and genotypes of functionally important polymorphous loci of some inflammation genes: proinflammatory cytokines genes IL-6, LTA and TNF, anti-inflammatory cytokine gene TGFB1 and CC chemokine receptor 5 gene CCR5 were analyzed in the patients with myocardial infarction (MI) of Russian ethnic descent (199 cases) and in the control group of the same ethnic descent (142 controls). | 20608170 |
| Guillain-Barre Syndrome, Paresis, Paralysed, Illness (finding) | Altered Intercellular Communication | Guillain-Barre syndrome, a randomly acquired inflammatory condition that can lead to progressive muscle weakness and paralysis, is a rare presentation in emergency departments, and differentiating its early stages from common viral illnesses can be difficult. | 20608399 |
| Inflammation, Lymphoma | Altered Intercellular Communication | Lymphoma was noted in 7 individuals and suppurative inflammation in 5. | 20608767 |
| ARCN1 gene, Inflammation, Malnutrition | Altered Intercellular Communication | Systemic inflammation has been suggested as one of the mechanisms of malnutrition in COPD. | 20609004 |
| Inflammation, Pulmonary Emphysema | Altered Intercellular Communication | Low BMI was associated with the severity of emphysema and systemic inflammation reflected by elevated a1-AT level. | 20609004 |
| Kidney Failure, Chronic, Inflammation | Altered Intercellular Communication | Despite adequate erythropoiesis-stimulating agent (ESA) supplementation, some ESRD patients still have suboptimal hemoglobin levels, and iron deficiency and inflammation are recognized as the two most common causes. | 20609184 |
| Refractory anemias, Rheumatoid Arthritis, Inflammation, Degenerative polyarthritis | Altered Intercellular Communication | The purpose of this study was to investigate the profile of histone deacetylase (HDAC) expression in the synovial tissue of rheumatoid arthritis (RA) compared with that of normal control and osteoarthritis (OA), and to examine whether there is a link between HDAC activity and synovial inflammation. | 20609223 |
| Inflammation, Lymphadenitis | Altered Intercellular Communication | Cases of inflammation of the upper airway including the oral cavity, laryngopharynx, palate tonsil and salivary gland, and cases of lymphadenitis were investigated. | 20609540 |
| Parotitis, Inflammation, Diabetes Mellitus | Altered Intercellular Communication | The presence of diabetes mellitus is associated with deep neck infection, aggravating parotitis and wide spread of inflammation. | 20609540 |
| Inflammation, Atrial Fibrillation, Atrial Fibrillation by ECG Finding | Altered Intercellular Communication | Inflammation has been implicated in the pathogenesis of postoperative atrial fibrillation (AF). | 20609593 |
| Inflammation | Altered Intercellular Communication | Postmortem examination of arteries showed no active inflammation. | 20609853 |
| Traumatic injury, Obesity | Altered Intercellular Communication | Obesity, like multiple trauma, is associated with an inflammatory condition that leads to an immunodeficient state. | 20610250 |
| Inflammation, Obesity, Atherosclerosis | Altered Intercellular Communication | Cathepsin S has been suggested provide a mechanistic link between obesity and atherosclerosis, possibly mediated via adipose tissue-derived inflammation. | 20610597 |
| Inflammation | Altered Intercellular Communication | The scrotum ruptured by itself, and the inflammation rapidly spread to the right inguinal area on 19 April. | 20610927 |
| Acute inflammation | Altered Intercellular Communication | In addition, one patient demonstrated modest acute neutrophilic inflammation with focal endothelial proliferation. | 20614301 |
| Rheumatoid Arthritis, Inflammation, Comorbidity, Cardiovascular Diseases | Altered Intercellular Communication | Prevalence and predictive factors of comorbidity in rheumatoid arthritis patients monitored prospectively from disease onset up to 20 years: lack of association between inflammation and cardiovascular disease. | 20615160 |
| Gastroesophageal reflux disease, Obesity | Altered Intercellular Communication | Gastroesophageal reflux disease (GERD) may link the obesity epidemic to an array of adverse health outcomes including chronic esophageal inflammation and, consequentially, to pathophysiological changes of the esophagus. | 20615162 |
| Hyperglycemia, Inflammation | Altered Intercellular Communication | Critical illness is commonly complicated by hyperglycaemia caused by mediators of stress and inflammation. | 20615210 |
| Joining Organizations with Leading Technologies, Nuchal Rigidity, Headache, Meningitis | Altered Intercellular Communication | The design was a double-blind, cross-sectional analysis of consecutive patients, independently comparing signs of meningeal inflammation (nuchal rigidity, head jolt accentuation of headache, Kernig's sign and Brudzinski's sign) elicited by internal medicine residents against an established reference standard (cerebrospinal fluid white cell count >5 white cells/mL). | 20615607 |
| Meningitis | Altered Intercellular Communication | Physical signs of meningeal inflammation do not help clinicians rule in or rule out meningitis accurately. | 20615607 |
| Inflammation | Altered Intercellular Communication | Cytoplasmic accumulation of mutant SOD1 was sensed by an ASC containing inflammasome and antagonized by autophagy, limiting caspase-1-mediated inflammation. | 20616033 |
| Inflammation, Meckel Diverticulum, Diverticulum | Altered Intercellular Communication | One patient had duplication of (double) Meckel's diverticulum without any inflammation in both the diverticulae. | 20616416 |
| Inflammation, Gangrene | Altered Intercellular Communication | Histopathological examination of these specimens confirmed 4 cases with inflammation; 2, with gangrene; and 1, with ulcerated gastric mucosa in the MD. | 20616416 |
| Cessation of life, Inflammation | Altered Intercellular Communication | Higher levels of IL-6 may reflect a chronic low-level systemic inflammation prospectively increasing the risk of death in the elderly. | 20617391 |
| Autoimmune Diseases, Inflammation | Altered Intercellular Communication | It is hypothesized that the restoration of normal menses was caused by reduced inflammation in the ovarian tissue and supports the hypothesis that the gut immune system can influence autoimmune disease and inflammation. | 20618099 |
| Refractory Cytopenia of Childhood, Renal Cell Carcinoma Pathway | Altered Intercellular Communication | This cytokine is a critical mediator of the Th1/Th2 balance and apoptosis potential and involved in the process of inflammation-mediated carcinogenesis in human organs, including renal cell carcinoma (RCC). | 20618516 |
| Inflammation, Herpes simplex type 2 infection | Altered Intercellular Communication | A 34-year-old man presented with a recurring painful inflammation of his left middle finger, caused by a herpes simplex type 2 infection. | 20619012 |
| Acute inflammation, Carcinoid, Goblet Cell | Altered Intercellular Communication | However, histological examination revealed a small goblet cell carcinoid, histological group C, with acute inflammation. | 20619032 |
| Inflammation, Fibrosis Assessment, Pulmonary Emphysema, Pulmonary Fibrosis | Altered Intercellular Communication | To approach the relationships among inflammation, immune response, and fibrosis in combined pulmonary fibrosis and emphysema (CPFE) through the observation of distributions of lymphocyte subtypes, the variation of Pro-collagen III N-terminal peptide (PIIINP) expression and the severity of pulmonary fibrosis (PF) in CPFE. | 20619092 |
| Inflammation, Idiopathic Pulmonary Fibrosis | Altered Intercellular Communication | The CPFE group showed significant inflammation predominated by T-lymphocytes, especially CD8+; T-lymphocyte, as compared with the IPF and control groups, hence pointing to the fact that a novel anti-lymphocytes and immune regulation strategy may be useful for disease intervention. | 20619092 |
| Inflammation, Metabolic Syndrome X | Altered Intercellular Communication | Systemic inflammation and the metabolic syndrome among middle-aged community volunteers. | 20619428 |
| Inflammation | Altered Intercellular Communication | Recent evidence suggests that markers of systemic inflammation may be included in the definition of the syndrome and play some role in its pathogenesis. | 20619428 |
| Inflammation, Metabolic Syndrome X | Altered Intercellular Communication | Inflammation was positively associated with this common factor, accounting for 54% of its variance and partially mediating statistical aggregation of the component factors comprising the metabolic syndrome. | 20619428 |
| Inflammation, Diabetes Mellitus, Non-Insulin-Dependent | Altered Intercellular Communication | The selenoprotein S (SELS) is a putative receptor for serum amyloid A, and recent studies have suggested that SELS may be a link between type 2 diabetes mellitus and inflammation. | 20619427 |
| Inflammation, Cellulitis, Infection, Necrosis | Altered Intercellular Communication | catheter-related soft tissue infections begin with local skin and soft tissue inflammation, which can progress to cellulitis or even tissue necrosis requiring aggressive surgical treatment. | 20619497 |
| Acute Coronary Syndrome | Altered Intercellular Communication | A comparative study of biomarkers for risk prediction in acute coronary syndrome-Results of the SIESTA (Systemic Inflammation Evaluation in non-ST-elevation Acute coronary syndrome) study. | 20619836 |
| Inflammation | Altered Intercellular Communication | ADMA may serve as a marker of systemic inflammation and may reflect functional immobility in AS. | 20620092 |
| Inflammation, Hypoxia, Anemia, hepcidin | Altered Intercellular Communication | Hepcidin, a small defensin-like peptide produced by hepatocytes, is modulated in response to anemia, hypoxia, or inflammation. | 20620527 |
| Renal Insufficiency, Inflammation, hepcidin, Anemia | Altered Intercellular Communication | Elevated hepcidin levels in heart transplant recipients may be due to low-grade inflammation, which is frequently encountered in this population, as well as probably to impaired renal function, but it does not seem to be a major pathogenic factor for anemia among this population. | 20620527 |
| Inflammation | Altered Intercellular Communication | This inflammation concerned the arteries of the deep dermis and of the superficial hypodermis. | 20620576 |
| Inflammation, Aortic Aneurysm, Abdominal | Altered Intercellular Communication | Markers of inflammation in men with small abdominal aortic aneurysm. | 20620767 |
| APP gene, Inflammation, Aortic Aneurysm, Abdominal | Altered Intercellular Communication | Markers of inflammation and fibrin turnover are elevated in individuals with a large (>55 mm) abdominal aortic aneurysm (AAA). | 20620767 |
| Inflammation | Altered Intercellular Communication | Thoracic, abdominal and sinus computed tomographic scan was normal and bronchoscopy showed a non specific mucosa inflammation. | 20621396 |
| Inflammation | Altered Intercellular Communication | We propose that this eventually triggers inflammation and the EGFRI rash. | 20621734 |
| Inflammation, Colorectal Carcinoma | Altered Intercellular Communication | Serine/threonine protein kinase 11 (STK11) and phosphatase tensin homolog deleted on chromosome 10 (PTEN) link insulin sensitivity and metabolic signaling to inflammation and other hormonal factors and colorectal cancer. | 20622004 |
| Inflammation, Colorectal Carcinoma | Altered Intercellular Communication | Serine/threonine protein kinase 11 (STK11) and phosphatase tensin homolog deleted on chromosome 10 (PTEN) link insulin sensitivity and metabolic signaling to inflammation and other hormonal factors and colorectal cancer. | 20622004 |
| Inflammatory Bowel Diseases, Rheumatoid Arthritis, Pyoderma Gangrenosum, Hematologic Neoplasms | Altered Intercellular Communication | Pyoderma gangrenosum is an inflammatory condition of the skin commonly associated with inflammatory bowel disease and rheumatoid arthritis, but also associated with various hematological malignancies. | 20622285 |
| palladium | Altered Intercellular Communication | The relationship between the malnutrition-inflammation complex syndrome and high levels of some adipokines in peritoneal dialysis (PD) patients is still unclear. | 20624111 |
| Inflammation, Body Weight, Overweight | Altered Intercellular Communication | The purpose of this study was to investigate the levels of plasma adipokines and inflammation and oxidative stress markers in overweight and normal weight PD patients. | 20624111 |
| palladium, Inflammation | Altered Intercellular Communication | Markers of oxidative stress and inflammation were also higher in the PD group. | 20624111 |
| Inflammation, Overweight | Altered Intercellular Communication | The statistical analysis indicated that there were no differences in oxidative stress, inflammation and ADMA concentration between the lean and overweight PD patients. | 20624111 |
| palladium, Inflammation | Altered Intercellular Communication | The severity of chronic inflammation and oxidative stress were not related to BMI in PD patients. | 20624111 |
| Inflammation | Altered Intercellular Communication | It is characterized by inflammation and cellular infiltration of small vessels and presence of anti-neutrophil cytoplasmic antibodies (ANCA). | 20624360 |
| Kidney Failure, Chronic, Inflammation, Comorbidity | Altered Intercellular Communication | Testosterone deficiency is a common finding among male ESRD patients, and it is independently associated with inflammation, cardiovascular co-morbidity and outcome. | 20624775 |
| Inflammation, Disease remission, Atherosclerosis, Corneal Endothelial Cell Loss, Aortic Valve Stenosis, Calcinosis | Altered Intercellular Communication | Calcific aortic valve stenosis is an active disease process characterized by mechanical stress, endothelial damage, lipid accumulation, inflammation, synthesis of extracellular matrix proteins, and calcification, reminiscent of atherosclerosis in many aspects. | 20625307 |
| Inflammation, Fibrosis Assessment | Altered Intercellular Communication | Moreover, the severity of lobular inflammation or fibrosis did not influence the MRI measurements. | 20625773 |
| Inflammation, Non-alcoholic Fatty Liver Disease, Hyperlipidemia | Altered Intercellular Communication | The effect of genotype on NAFLD is probably mediated through chronic low-grade systemic inflammation rather than through dislipidemia. | 20625834 |
| Gilles de la Tourette syndrome | Altered Intercellular Communication | The analysis of selected neurotransmitter concentrations in serum of patients with Tourette syndrome. | 20625961 |
| Gilles de la Tourette syndrome | Altered Intercellular Communication | Metabolic disturbances of excitatory and inhibitory neurotransmitters are implicated in pathogenesis of Tourette syndrome (TS). | 20625961 |
| Inflammation | Altered Intercellular Communication | Since oxidative stress and inflammation impair insulin actions as well, it is conceivable that AGEs may play some role in insulin resistance. | 20626403 |
| Inflammation, Thrombosis, deficiency aspects | Altered Intercellular Communication | Because inflammation can potentially mask deficiency states or mimic an increased risk of thrombosis, FVIII, VWF and Fg determinations should be supplemented by measurements of hsCRP. | 20627205 |
| Inflammation, Myopathy, Myelitis, Transverse | Altered Intercellular Communication | Transverse myelitis, which is characterised by bilateral inflammation of the spinal cord and myelin destruction, is associated with myopathy, autonomic dysreflexia and pulmonary aspiration. | 20627694 |
| Inflammation, Sleep Apnea, Obstructive, Obesity | Altered Intercellular Communication | Obstructive Sleep Apnea Syndrome (OSAS) is associated with inflammation, but obesity may be a confounding factor. | 20628509 |
| Inflammation, Sleep Apnea, Obstructive | Altered Intercellular Communication | OSAS patients had significantly higher TNF-alpha levels (P < .001) while no other difference in the examined inflammation markers was recorded between groups. | 20628509 |
| Inflammation, Sleep Apnea, Obstructive | Altered Intercellular Communication | Obese OSAS patients have elevated TNF-alpha levels compared to BMI-matched controls, suggesting a role of OSAS in promoting inflammation, possibly mediated by TNF-a. | 20628509 |
| Inflammation | Altered Intercellular Communication | Fiberoptic bronchoscope-guided biopsy of the mass on two occasions showed acute-on-chronic inflammation. | 20628853 |
| Inflammation | Altered Intercellular Communication | External root resorption can be found in the furcation area of mandibular teeth as a result of chronic inflammation. | 20629542 |
| Inflammation, Diabetes Mellitus, Non-Insulin-Dependent, Obesity | Altered Intercellular Communication | Chronic inflammation is linked to type 2 diabetes (T2DM), so we investigated correlations between obesity, blood glucose levels, and inflammation in T2DM patients. | 20630610 |
| Inflammation, Ulcerative Colitis | Altered Intercellular Communication | In unmethylated UC-background mucosa, DAPK protein expression increased with activity of UC-associated inflammation, suggesting a protective role of the pro-apoptotic DAPK during the chronic inflammatory process of UC. | 20630662 |
| Inflammation, Failure (biologic function) | Altered Intercellular Communication | The major causes of failure were unsuccessful initial healing and replacement root resorption with periodontal inflammation. | 20630706 |
| Communicable Diseases, Inflammation, Immunocompromised Host, Malignant Neoplasms | Altered Intercellular Communication | Overall diagnostic efficacy between immunocompetent and immunocompromised patients was comparable (P = .2); however, detection of infection or inflammation in individual groups was lower compared with detection of malignancy (P = .002 and P = .06, respectively). | 20630827 |
| Inflammation | Altered Intercellular Communication | None of the parameters correlated with disease severity and markers of systemic inflammation. | 20631813 |
| AURKAIP1 gene, Inflammation | Altered Intercellular Communication | Prominent intra-islet inflammation and decreased vascularity in AIP may contribute to diabetogenic effects. | 20632032 |
| Inflammation, Atrophic | Altered Intercellular Communication | We also studied foci with partial or complete atrophy without inflammation. | 20632094 |
| Inflammatory Bowel Diseases, Gastrointestinal inflammation, Ulcerative Colitis | Altered Intercellular Communication | Serum was collected from 191 patients with IBD (85 with ulcerative colitis (UC) and 106 with CD), 29 cases with other causes of intestinal inflammation and 96 healthy controls. | 20632100 |
| Autistic Disorder | Altered Intercellular Communication | Dysfunction of cerebral cortex in autism is thought to involve alterations in inhibitory neurotransmission. | 20632321 |
| Inflammation, Hypoxia, Varicosity | Altered Intercellular Communication | Pathogenic mechanisms in varicose vein disease: the role of hypoxia and inflammation. | 20632821 |
| Inflammation, Impaired cognition | Altered Intercellular Communication | After adjustment for demographics, chronic health conditions, health status, and inflammation, the association between reduced hemoglobin and cognitive impairment was attenuated and no longer significant, including among those with hemoglobin >=2 g/dL below the WHO threshold (odds ratio 1.39, 95% confidence interval = 0.94-2.04). | 20634281 |
| Inflammation, Inflammatory disorder | Altered Intercellular Communication | Regulatory T lymphocytes (Treg) play a fundamental importance in modulating the relative balance between inflammation and immune tolerance, and alterations of these cells are observed in inflammatory diseases. | 20634592 |
| Inflammation | Altered Intercellular Communication | A state of low-grade systemic inflammation may underlie this constellation of risk factors. | 20634647 |
| Inflammation, Periodontal Diseases | Altered Intercellular Communication | Chronic inflammatory conditions, such as periodontal disease, may contribute to systemic inflammation and development of MetS. | 20634647 |
| Inflammation, Alveolar Bone Loss, Periodontal Diseases, ETV3 wt Allele | Altered Intercellular Communication | The association of alveolar bone loss to MetS is consistent with the hypothesis that destructive periodontal disease may contribute to the development of MetS and elevations in systemic inflammation. | 20634647 |
| Inflammation, Periodontal Diseases, ETV3 wt Allele | Altered Intercellular Communication | Longitudinal studies are necessary to clarify the role of periodontal disease in the development of MetS and conditions associated with chronic inflammation. | 20634647 |
| Inflammation, Periodontal Diseases | Altered Intercellular Communication | Chronic inflammatory conditions, such as periodontal disease, may contribute to systemic inflammation and development of MetS. | 20634647 |
| allergic inflammation | Altered Intercellular Communication | The demonstration of proinflammatory neuropeptides in NAL and suppression of their release after allergen challenge caused by a topical corticosteroid suggest a role for neuropeptides in allergic inflammation. | 20635787 |
| Airway structure | Altered Intercellular Communication | Leukotrienes and isoprostanes are biomarkers of airway inflammation and oxidative stress that can be detected in exhaled breath condensate (EBC). | 20635789 |
| Airway structure | Altered Intercellular Communication | Our findings suggest that EBC is a noninvasive method for airway inflammation and oxidative stress assessment. | 20635789 |
| Tissue damage, Inflammation, Ulcer | Altered Intercellular Communication | Our study identifies PG as a paradigm of neutrophil-mediated inflammation, with proinflammatory cytokines/chemokines and MMPs acting as important effectors for the tissue damage, particularly in ulcerative and bullous PG where damage is stronger. | 20636397 |
| Inflammation, Observation Method - Coagulation, Neoplasms | Altered Intercellular Communication | Microvesicles are involved in different pathological processes such as inflammation, coagulation and tumor progression. | 20637189 |
| Inflammation, Atrial Fibrillation by ECG Finding | Altered Intercellular Communication | By this method we investigated the association of inflammation with platelet activation in patients with nonvalvular atrial fibrillation (NVAF). | 20637189 |
| Inflammation | Altered Intercellular Communication | Inflammation may be involved in the activation of platelets in NVAF. | 20637189 |
| Inflammation | Altered Intercellular Communication | Diffuse type of inflammation was associated with T2DM. | 20638146 |
| Inflammation, Chief complaint (finding), Diabetes Mellitus | Altered Intercellular Communication | Inadequately controlled diabetes with Candida-associated DS was linked to a high incidence of an extensive type of inflammation, oral complaints and associated conditions. | 20638146 |
| Vasculitis | Altered Intercellular Communication | Recent studies suggest that C-reactive protein (CRP) reflects vascular wall inflammation and can predict adverse events. | 20638228 |
| Disability, Inflammation, Congenital Abnormality | Altered Intercellular Communication | Chronic inflammation can lead to permanent structural changes, deformity and disability. | 20638271 |
| APP gene, Inflammation, Aortic Aneurysm, Abdominal | Altered Intercellular Communication | In patients with abdominal aortic aneurysms (AAA), the changes in nitric oxide metabolism in close association with inflammation, appear to play a leading role in the aetiopathology of this disease, although it is still not clear. | 20638617 |
| Inflammation, Endothelial dysfunction | Altered Intercellular Communication | The positive correlation between the FMDB and CRP supports the hypothesis that inflammation and endothelial dysfunction are processes associated with the physiopathology of AAA and vary with their growth. | 20638617 |
| Hypoxia | Altered Intercellular Communication | We analyzed the relationship between aging and hypoxia by examining oxidative stress and inflammation-related cytokines. | 20639132 |
| vascular inflammations, Microvascular Angina | Altered Intercellular Communication | Increased oxidative stress and vascular inflammation have been demonstrated in patients with cardiac syndrome X (CSX). | 20639239 |
| Parkinson Disease, Inflammation, palladium | Altered Intercellular Communication | Interestingly, both inflammation and oxidative stress, which play a role in the etiology of Parkinson's disease (PD), may accelerate telomere shortening. | 20639300 |
| Cerebrovascular accident | Altered Intercellular Communication | Carotid plaque inflammation is associated with cerebral microembolism in patients with recent transient ischemic attack or stroke: a pilot study. | 20639303 |
| Inflammation | Altered Intercellular Communication | These findings strengthen the notion that embolic events distal to carotid stenoses are related to plaque inflammation, and FDG PET may be useful in the investigation of culprit carotid lesions. | 20639303 |
| Inflammation, Depression, CTCAE, AUTONOMIC NERVOUS SYSTEM DYSFUNCTION | Altered Intercellular Communication | Autonomic nervous system dysfunction and inflammation contribute to the increased cardiovascular mortality risk associated with depression. | 20639389 |
| Inflammation, Depression, CTCAE, Cardiovascular Diseases | Altered Intercellular Communication | To investigate prospectively whether autonomic nervous system (ANS) dysfunction and inflammation play a role in the increased cardiovascular disease (CVD)-related mortality risk associated with depression. | 20639389 |
| Autonomic nervous system, Inflammation, Depression, CTCAE | Altered Intercellular Communication | Cox proportional hazards models were used to investigate the mortality risk associated with depression, ANS, and inflammation markers, adjusting for demographic and clinical covariates. | 20639389 |
| Inflammation, Depression, CTCAE, physiopathological | Altered Intercellular Communication | Depression was associated with ANS dysfunction (DFA(1), p = .018), and increased inflammation markers (white blood cell count, p = .012, fibrinogen p = .043) adjusting for covariates. | 20639389 |
| Inflammation, Depression, CTCAE, Autonomic nervous system disorders | Altered Intercellular Communication | Autonomic dysfunction and inflammation contribute to the increased cardiovascular mortality risk associated with depression, but a large portion of the predictive value of depression remains unexplained by these neuroimmunological measures. | 20639389 |
| Chronic lymphocytic inflammation, Pontine structure, Clippers | Altered Intercellular Communication | Chronic lymphocytic inflammation with pontine perivascular enhancement responsive to steroids (CLIPPERS). | 20639547 |
| Encephalomyelitis, Pontine structure, Clippers, Chronic lymphocytic inflammation | Altered Intercellular Communication | In this article we report eight patients with a clinically and radiologically distinct pontine-predominant encephalomyelitis we have named 'chronic lymphocytic inflammation with pontine perivascular enhancement responsive to steroids' (CLIPPERS). | 20639547 |
| Chronic lymphocytic inflammation, Pontine structure | Altered Intercellular Communication | Chronic lymphocytic inflammation with pontine perivascular enhancement responsive to steroids is a definable, chronic inflammatory central nervous system disorder amenable to immunosuppressive treatment. | 20639547 |
| Abnormal renal function, Inflammation, Chronic Kidney Diseases, Cardiovascular Diseases | Altered Intercellular Communication | Chronic kidney disease (CKD) is characterized by progressive kidney dysfunction accompanied by accumulation of uremic toxins and a potential disequilibrium between the redox status and the generation of prooxidants, resulting in oxidative stress and chronic inflammation which is associated with complications (particularly cardiovascular disease) in this population. | 20639676 |
| Inflammation, Chronic Kidney Diseases | Altered Intercellular Communication | These findings indicate the importance of renal function in the complications of CKD related to oxidative stress and inflammation. | 20639676 |
| Degenerative polyarthritis, Pain Distress Question, Morning stiffness - joint, Erythema | Altered Intercellular Communication | Etodolac-paracetamol was significantly superior to etodolac alone in reducing pain intensity (P<0.001), achieving pain relief (P<0.05) during the first 4 hours after the study dose administration, and resolution of the clinical signs and symptoms of OA flare-up such as morning stiffness, swelling/inflammation, and erythema. | 20639739 |
| Inflammation, Cytokeratin, Exacerbation of cGVHD | Altered Intercellular Communication | Post operative inflammation were evaluated by slit lamp examination of cells, flares & keratic precipitate (KP). | 20639824 |
| Inflammation, Inflammatory dermatosis, Pustulosis of Palms and Soles | Altered Intercellular Communication | Earlier findings indicate the acrosyringium as the target for the inflammation in the chronic and intensely inflammatory skin disease palmoplantar pustulosis (PPP). | 20640434 |
| Inflammation, Malnutrition, Cardiovascular Diseases | Altered Intercellular Communication | In a pre-dialysis population, female gender, cardiovascular disease, malnutrition and inflammation are associated with a higher ESA/Hb index. | 20640598 |
| Inflammation | Altered Intercellular Communication | Red ginseng extract increased CD34(+) , CXCR4(+) and CD117(+) circulating angiogenic cell mobilization and decreased inflammation in AMI patients, thereby improving CFR during the 8-month follow-up. | 20641058 |
| Failure (biologic function) | Altered Intercellular Communication | Focused parathyroidectomy guided by intraoperative parathyroid hormone monitoring (IPM) may lead to higher failure rates because of missed multiglandular disease. | 20644124 |
| vascular inflammations, Endothelial dysfunction | Altered Intercellular Communication | Resveratrol (RV)-induced SirT1 activation also improves endothelial dysfunction and suppresses vascular inflammation. | 20644332 |
| Inflammation, Perforation (observation) | Altered Intercellular Communication | Diagnostic value of inflammation markers in predicting perforation in acute sigmoid diverticulitis. | 20645093 |
| Inflammation, Perforation (observation) | Altered Intercellular Communication | The importance of inflammation markers in predicting perforation in acute sigmoid diverticulitis is not well known. | 20645093 |
| Chronic kidney disease stage 5, Inflammation, Cardiovascular Diseases | Altered Intercellular Communication | Apelin: a potential link between inflammation and cardiovascular disease in end stage renal disease patients. | 20645679 |
| Autoimmune Diseases, Inflammation | Altered Intercellular Communication | T helper type 17 (Th17) and regulatory T cells (T(reg) ) play an important role in the pathogenesis of inflammation and autoimmune disorders. | 20646003 |
| Inflammation, Fibrosis Assessment | Altered Intercellular Communication | These findings suggest that the CXCL12/CXCR4 axis contributes to inflammation in UIP and f-NSIP by promoting the accumulation CXCR4(+) lymphocytes, and a decrease of Treg is correlated with the severity of fibrosis in UIP. | 20646340 |
| Pneumonitis | Altered Intercellular Communication | And it has a close correlation with CD4+ and CD8+ lymphocytes in lung, lung parenchyma destruction, pulmonary inflammation, pulmonary artery reconstruction and airflow limitation. | 20646637 |
| Inflammation, Edema | Altered Intercellular Communication | Magnetic resonance imaging revealed a cervical epidural abscess, and accompanying edema or inflammation of the right side of the spinal cord at the C5 level. | 20647654 |
| Fibrosis Assessment, Interstitial inflammation | Altered Intercellular Communication | We report a 23-year-old woman with interstitial inflammation and fibrosis associated with deposition of surfactant proteins in the airways. | 20647661 |
| Airway structure, Inflammation, Fibrosis Assessment | Altered Intercellular Communication | Biopsy of the lung showed multiple focal lesions containing dilated airways with inflammation and fibrosis. | 20647661 |
| Interstitial infiltrates, Interstitial inflammation | Altered Intercellular Communication | The higher LVD was significantly associated with interstitial inflammation, and the newly formed lymph vessels were accompanied by diffuse and nodular interstitial infiltrates composed mainly of CD20(+) B cells and CD27(+) plasma cells. | 20648479 |
| ARCN1 gene, Inflammation, Chronic Obstructive Airway Disease | Altered Intercellular Communication | Chronic obstructive pulmonary disease (COPD) is characterized by chronic inflammation and oxidant/antioxidant imbalance. | 20648694 |
| Inflammation | Altered Intercellular Communication | Moreover, a close correlation was found between the condition of bowel inflammation and that of mucocutaneous lesions. | 20649713 |
| Degenerative polyarthritis, Inflammation | Altered Intercellular Communication | In OA bone, expression of critical regulators of osteoblast differentiation (TWIST1) and function (PTEN, TIMP4) were decreased, while genes associated with inflammation (SMAD3, CD14) were increased. | 20650323 |
| Adenocarcinoma of lung (disorder) | Altered Intercellular Communication | Recent evidence suggests that the hormonal status may contribute to the pathogenesis of lung adenocarcinoma. | 20650541 |
| Inflammation, Atherosclerosis | Altered Intercellular Communication | The immune response mediated by the antigen-specific T cells, especially that mediated by type 1 T helper cells secreting IFN-gamma, may play an important role in the instability of plaques, and CRP may promote the inflammation of atherosclerosis through the effects on the specific immune response to oxLDL. | 20650780 |
| ARCN1 gene, Inflammation, Chronic Obstructive Airway Disease | Altered Intercellular Communication | Chronic obstructive pulmonary disease (COPD) is characterised by neutrophilic inflammation in the airways and these neutrophils contribute to the production of inflammatory mediators. | 20650986 |
| Inflammation | Altered Intercellular Communication | In conclusion, dexamethasone induces a pro-inflammatory shift in the IL-1b:sIL-1Ra cytokine balance in neutrophils in vitro, which might contribute to a lack of endogenous anti-inflammatory signals to dampen inflammation in vivo. | 20650986 |
| Inflammation | Altered Intercellular Communication | In conclusion, dexamethasone induces a pro-inflammatory shift in the IL-1b:sIL-1Ra cytokine balance in neutrophils in vitro, which might contribute to a lack of endogenous anti-inflammatory signals to dampen inflammation in vivo. | 20650986 |
| Adenocarcinoma, Inflammation, Thickening of pleura, Lymphoma | Altered Intercellular Communication | The other five patients had pleural thickening (two patients), metastatic adenocarcinoma (one patient), chronic inflammation (one patient), and malignant lymphoma (one patient). | 20651171 |
| Hepatitis, Fibrosis Assessment, Fatty degeneration, Hepatitis C, Diabetes Mellitus, Non-Insulin-Dependent | Altered Intercellular Communication | When surrogate markers of liver inflammation (alanine aminotransferase, aspartate aminotransferase/alanine aminotransferase ratio and alpha-fetoprotein) were removed from the model, type 2 diabetes mellitus (P=0.001), steatosis (P=0.03) and duration of HCV infection by 10-year intervals (P=0.02) were associated with advanced fibrosis. | 20652161 |
| Inflammation, Mycoses, Ear Inflammation | Altered Intercellular Communication | We have found it satisfactory in treating otitis media and other intractable inflammation and fungal infection of the external auditory canal. | 20653194 |
| Communicable Diseases, Inflammation, Cholesteatoma | Altered Intercellular Communication | Although this usually cannot completely cure middle-ear and attic cholesteatoma, its effectiveness in cases of EACC and MCC should be recognized in infection and inflammation with cholesteatoma. | 20653194 |
| Inflammation | Altered Intercellular Communication | Additional findings such as flow velocity, inflammation, and disruption of the epidermal architecture could be documented. | 20653723 |
| Mastitis, Fibrosis Assessment | Altered Intercellular Communication | The three types of mastitis presented similar ultrasound findings and shared certain histological features including fibrosis and diffuse or lobulocentric inflammation. | 20653779 |
| Inflammation, Cardiovascular system | Altered Intercellular Communication | This study investigated whether inflammation could be part of the mechanism leading to temperature-related cardiovascular deaths. | 20653951 |
| Inflammation | Altered Intercellular Communication | Cumulative exposure to decreased temperature is associated with an increase in inflammation marker levels among elderly men. | 20653951 |
| Inflammation, Cardiovascular system | Altered Intercellular Communication | This suggests that inflammation markers are part of intermediate processes, which may lead to cold-, but not heat-, related cardiovascular deaths. | 20653951 |
| Inflammation, Dyslipidemias, Atherosclerosis | Altered Intercellular Communication | Patients undergoing continuous ambulatory peritoneal dialysis (CAPD) often have inflammation and dyslipidemia that accelerate to atherosclerosis. | 20654604 |
| Granulomatous inflammation, Infiltration | Altered Intercellular Communication | Biopsy of his right superficial temporal artery revealed a granulomatous inflammation with multinucleated giant cell infiltration. | 20654795 |
| Inflammation, Dyssomnias, Fatigue | Altered Intercellular Communication | Individuals with underlying inflammation present with a high prevalence of non-specific co-morbid symptoms including sleep disturbance and fatigue. | 20656013 |
| Inflammation | Altered Intercellular Communication | Relative loss of slow wave sleep may be one pathway through which cellular inflammation leads to daytime fatigue. | 20656013 |
| Prostate carcinoma, prostatitis | Altered Intercellular Communication | [Predictive value of the asymptomatic prostatic inflammation in the development of prostate cancer]. | 20656273 |
| Inflammation, Primary malignant neoplasm | Altered Intercellular Communication | Several studies have tried to show a link between inflammation and cancer. | 20656273 |
| Inflammation, Atrophic | Altered Intercellular Communication | Inflammation and several histological criterions were evaluated: acute/chronic and focal/diffuse inflammation, atrophy, high grade PIN (HGPIN) and ASAP. | 20656273 |
| Inflammation, Structure of posterior cerebral artery | Altered Intercellular Communication | According to these data, the presence and type of histological inflammation on initial prostate biopsies did not seem to be a risk factor for the development of PCa. | 20656273 |
| Inflammation, Foveolar-Type Adenoma, Duodenitis | Altered Intercellular Communication | Of 28,210 patients with duodenal biopsy specimens, 80.9% were healthy, 2.1% had active duodenitis, 2.2% gastric foveolar metaplasia without active inflammation ("peptic duodenopathy"), 4.8% gastric foveolar metaplasia with active inflammation ("peptic duodenitis"), and 1.9% gastric heterotopia. | 20656325 |
| Inflammation, Gastric metaplasia, Helicobacter-associated gastritis, Foveolar-Type Adenoma, Duodenitis | Altered Intercellular Communication | Helicobacter pylori was documented in 9.8% of patients with normal duodenum, 6.9% of those with gastric metaplasia without active inflammation, 15.8% of those with active duodenitis, and 29.1% of those with gastric foveolar metaplasia with active inflammation; 2.2% of 543 patients with gastric heterotopia had H pylori gastritis. | 20656325 |
| Inflammation, Metaplasia | Altered Intercellular Communication | Helicobacter pylori was detected in the metaplastic epithelium of 67.6% of patients with active inflammation and in 16.4% of those with metaplasia without inflammation. | 20656325 |
| Inflammation, Fibrous | Altered Intercellular Communication | Polyethylene wear particles do not induce inflammation or gelatinase (MMP-2 and MMP-9) activity in fibrous tissue interfaces of loosening total hip arthroplasties. | 20656340 |
| Inflammation, Genes, Wilms Tumor | Altered Intercellular Communication | Long-term administration of Wilms tumor-1 peptide vaccine in combination with gemcitabine causes severe local skin inflammation at injection sites. | 20656693 |
| Inflammation, Liver Cirrhosis, Fatty Liver Disease | Altered Intercellular Communication | NADPH, a marker of inflammation and fibrinogenic activity in the liver, is increased in patients with NASH and those with cirrhosis. | 20656836 |
| Inflammation, Pulmonary Emphysema | Altered Intercellular Communication | Role of breast regression protein-39 in the pathogenesis of cigarette smoke-induced inflammation and emphysema. | 20656949 |
| Inflammation | Altered Intercellular Communication | These studies demonstrate a novel regulatory role of BRP-39/YKL-40 in CS-induced inflammation and emphysematous destruction. | 20656949 |
| Inflammatory abnormality of the eye, Atopic keratoconjunctivitis | Altered Intercellular Communication | Case report of restoration of the corneal epithelium in a patient with atopic keratoconjunctivitis resulting in amelioration of ocular allergic inflammation. | 20657166 |
| Keratoconjunctivitis, Vernal, Conjunctivitis, Atopy | Altered Intercellular Communication | Atopic and vernal keratoconjunctivitis are severe types of ocular allergic disease characterized not only by conjunctival inflammation but also by corneal involvement. | 20657166 |
| Inflammatory abnormality of the eye | Altered Intercellular Communication | In vitro studies have suggested that breakdown of corneal epithelial barrier function and subsequent activation of stromal fibroblasts may amplify ocular allergic inflammation. | 20657166 |
| Corneal endothelial plaque, Conjunctivitis | Altered Intercellular Communication | Surgical removal of corneal plaque and administration of autologous fibronectin eyedrops resulted not only in resurfacing of the corneal epithelium but also in amelioration of conjunctival inflammation. | 20657166 |
| Conjunctivitis | Altered Intercellular Communication | This case suggests that loss of corneal epithelial integrity likely exacerbates conjunctival allergic inflammation and that restoration or maintenance of the barrier function of the corneal epithelium may be one of the important targets for the treatment of severe ocular allergic diseases. | 20657166 |
| Inflammation, Obesity | Altered Intercellular Communication | The relationships among stress, obesity, and inflammation in women remain unclear. | 20658213 |
| Communicable Diseases, Inflammation | Altered Intercellular Communication | Postoperative systemic inflammation response syndrome(SIRS) and infection were evaluated. | 20658369 |
| Inflammation, Diabetes Mellitus, Non-Insulin-Dependent, Obesity | Altered Intercellular Communication | Substance P is associated with the development of obesity, chronic inflammation and type 2 diabetes mellitus. | 20658441 |
| Obesity | Altered Intercellular Communication | Substance P (SP) is an important neurotransmitter and is an important pathogenic factor in obesity. | 20658441 |
| Inflammation | Altered Intercellular Communication | Assessment of anterior chamber inflammation after intravitreal bevacizumab injection in different ocular exudative diseases. | 20658459 |
| Inflammation | Altered Intercellular Communication | To investigate the inflammation of the anterior chamber after intravitreal bevacizumab injection in different ocular exudative diseases. | 20658459 |
| Nonproliferative diabetic retinopathy, Inflammation, Choroidal Neovascularization, Edema | Altered Intercellular Communication | The extent of inflammation in the anterior chamber did not change after intravitreal bevacizumab injection in patients with nonproliferative diabetic retinopathy, choroidal neovascularization secondary to age-related macular degeneration, or macular edema due to branch or central vein occlusion. | 20658459 |
| Inflammation, Bronchial Obstruction, Bronchiectasis, Aspergillosis, Allergic Bronchopulmonary, Fibrosis Assessment, Mucus retention, Respiratory Failure | Altered Intercellular Communication | Recurrent episodes of bronchial obstruction, inflammation, and mucoid impaction occur in ABPA and results in bronchiectasis, fibrosis, and respiratory failure. | 20658484 |
| Aspergillosis, Allergic Bronchopulmonary, Inflammation, Fungal Colonization, Lung Injury | Altered Intercellular Communication | The treatment of ABPA includes corticosteroids to reduce the acute inflammation and intraconazole to reduce the fungal colonization load in order to reduce lung injury. | 20658484 |
| Inflammation, activation of blood coagulation via clotting cascade | Altered Intercellular Communication | The relationship between inflammation, obesity-related proteins and tissue factor (TF), the major initiator of the extrinsic clotting cascade, is not well understood. | 20659134 |
| Inflammation | Altered Intercellular Communication | Within 24 h after admission, moderate elevation of TC level seemed to increase the resistance to inflammation and hence improved the survival rate in patients with SAP, and reduced the in-hospital mortality. | 20659228 |
| Inflammation, Diabetes Mellitus, Non-Insulin-Dependent, Impaired lung function | Altered Intercellular Communication | Inadequate glucose control in type 2 diabetes is associated with impaired lung function and systemic inflammation: a cross-sectional study. | 20659337 |
| Inflammation, Diabetes Mellitus | Altered Intercellular Communication | Inadequate glucose control may be simultaneously associated with inflammation and decreased lung function in type 2 diabetes. | 20659337 |
| Inflammation, Cardiovascular Diseases | Altered Intercellular Communication | Invited commentary: human cytomegalovirus, inflammation, cardiovascular disease, and mortality. | 20660119 |
| Inflammation, Autoimmune Chronic Hepatitis | Altered Intercellular Communication | Our data suggest that elevated serum F-actin antibody titers are commonly encountered in HCV-infected patients and may reflect more active inflammation in liver biopsy samples, similar to autoimmune hepatitis. | 20660325 |
| methyldopa, Inflammation | Altered Intercellular Communication | We propose that the impaired binding of the 402H variant to Bruch's membrane results in an overactivation of the complement pathway leading to local chronic inflammation and thus contributes directly to the development and/or progression of AMD. | 20660596 |
| Inflammation, Atherosclerosis, Giant Cell Arteritis, GCA gene, Cerebrovascular accident | Altered Intercellular Communication | It is not established whether the increased risk of stroke in patients with giant cell arteritis (GCA) is because of atherosclerosis, persistent arterial inflammation, or an iatrogenic effect of corticosteroids. | 20661069 |
| Inflammation, Compassion Fatigue | Altered Intercellular Communication | More than 2 mitotic figures per lesion can usually be explained either by the nevus subtype, young patient age, traumatization, or inflammation. | 20661119 |
| Asbestos-Related Lung Disorder, Pleurisy, 1-methyl-1-piperidinomethane sulfonate | Altered Intercellular Communication | PET/CT might be more helpful than plasma osteopontin for distinguishing benign asbestos-related pleural diseases from MPM, and the SUVmax in benign asbestos-related pleural diseases may reflect changes in pleural inflammation. | 20661695 |
| Hepatitis B, Impaired T cell function, Hepatitis | Altered Intercellular Communication | Intrahepatic levels of PD-1/PD-L correlate with liver inflammation in chronic hepatitis B. Programmed cell death-1 (PD-1) represents a mechanism of T-cell dysfunction in hepatitis B virus (HBV) persistence. | 20661763 |
| Inflammation, Complete atrioventricular block | Altered Intercellular Communication | Within the CHB patients, the increases in labeling indexes of PD-1 and PD-L paralleled the degree of inflammation. | 20661763 |
| Chronicity, Inflammation, Complete atrioventricular block, Immune System Diseases | Altered Intercellular Communication | These results suggest that over-expression of PD-1, PD-L1 and PD-L2 within liver may participate in local immune dysfunction, which could be one of the mechanisms involved in the chronicity of HBV infection and chronic inflammation seen in CHB patients. | 20661763 |
| Inflammation, Papilledema | Altered Intercellular Communication | Despite topical steroids and mydriatics, inflammation worsened and bilateral optic nerve swelling developed. | 20662661 |
| Inflammatory abnormality of the eye | Altered Intercellular Communication | Oral corticosteroids settled the ocular inflammation, and optic nerve function recovered. | 20662661 |
| Malignant neoplasm of urinary bladder, Inflammatory abnormality of the eye | Altered Intercellular Communication | Ocular inflammations following BCG therapy for bladder cancer are rare, and little is known about the management of such cases. | 20662661 |
| Inflammation, Atherosclerosis, diabetic, Endothelial dysfunction, Hypertension, CTCAE | Altered Intercellular Communication | Endothelial dysfunction is a common feature in type-2 diabetic patients and in hypertension, and is associated with inflammation, increased levels of circulating soluble adhesion molecules, and atherosclerosis. | 20662732 |
| Endothelial dysfunction | Altered Intercellular Communication | Malnutrition-inflammation score and endothelial dysfunction in hemodialysis patients. | 20663689 |
| Inflammation, Hyperparathyroidism, Diabetes Mellitus | Altered Intercellular Communication | In patients with diabetes, inflammation or severe hyperparathyroidism, the REE estimated by the Harris and Benedict equation was equivalent to that measured by indirect calorimetry. | 20663791 |
| Inflammation, Diabetes Mellitus | Altered Intercellular Communication | Association between systemic inflammation and incident diabetes in HIV-infected patients after initiation of antiretroviral therapy. | 20664016 |
| Inflammation, Diabetes Mellitus | Altered Intercellular Communication | To determine whether systemic inflammation after initiation of HIV-antiretroviral therapy (ART) is associated with the development of diabetes. | 20664016 |
| Inflammation, Diabetes Mellitus | Altered Intercellular Communication | These findings suggest that systemic inflammation may contribute to diabetes pathogenesis among HIV-infected patients. | 20664016 |
| Inflammation, Hemorrhage, Necrosis | Altered Intercellular Communication | We semi-quantitatively analysed intensity of inflammation, necrosis, haemorrhage and lipid depletion. | 20665002 |
| Inflammation, Hemorrhage, Septic Shock, Necrosis | Altered Intercellular Communication | In adrenal cortex, in patients and not in animals, global scores for inflammation (p = 0.002), necrosis (p = 0.009) and haemorrhage (p = 0.009) were significantly higher in septic shock than in controls. | 20665002 |
| Inflammation, Hemorrhage, Septic Shock, Necrosis | Altered Intercellular Communication | Similarly, in zona fasciculata, in patients and not in animals, scores for inflammation (p = 0.007), necrosis (p = 0.023) and haemorrhage (p = 0.023) were significantly higher in septic shock than in controls. | 20665002 |
| Sepsis, Inflammation, Hemorrhage, Necrosis | Altered Intercellular Communication | In patients, sepsis was associated with inflammation, necrosis and haemorrhage predominantly in zona fasciculata. | 20665002 |
| ARCN1 gene, Inflammation | Altered Intercellular Communication | At present, COPD is known to be a systemic disease resulting from generalized inflammation which affects the function of many organs. | 20665447 |
| Inflammation | Altered Intercellular Communication | Generalized inflammation is recognized from increased serum concentration of inflammatory cytokines. | 20665447 |
| Inflammation | Altered Intercellular Communication | Exclusion criteria included coexistence of other diseases and/or medication causing an increase of markers of inflammation. | 20665447 |
| Inflammation, Atrophic, Skeletal muscle weakness | Altered Intercellular Communication | MCK-bAPP mice show an age-dependent increase in [Ca(2+)](i) along with a reduction in depolarization-evoked Ca(2+) release, which appear well before the other reported aspects of IBM, such as inclusion formation, inflammation, centralized nuclei, atrophy, and skeletal muscle weakness. | 20665519 |
| Carcinoma, Primary infertility | Altered Intercellular Communication | Primary and bilateral tubal carcinoma is associated with long-standing granulomatous inflammation and primary infertility: a case report. | 20666969 |
| Granulomatous inflammation, Non-Metastatic Carcinoma, Primary infertility | Altered Intercellular Communication | We report a case of bilateral and primary tubal carcinoma associated with granulomatous inflammation and long-standing primary infertility. | 20666969 |
| Granulomatous inflammation, Primary infertility, Abdominal Pain | Altered Intercellular Communication | A 38-year-old woman with a 17-year history of primary infertility presented with lower abdominal pain and granulomatous inflammation in the endometrial biopsy. | 20666969 |
| Pelvic Inflammatory Disease | Altered Intercellular Communication | A definitive diagnosis could be made on the histopathological examination in our case with the evidence of chronic pelvic inflammation. | 20666969 |
| Carcinogenesis, Pelvic Inflammatory Disease | Altered Intercellular Communication | Our findings suggest that chronic pelvic inflammation may play a role in carcinogenesis in the tubes of infertile women. | 20666969 |
| Fibrinoid necrotizing inflammation | Altered Intercellular Communication | Interestingly, the cause of autograft failure was not related to the rheumatoid inflammation process. | 20667306 |
| Inflammation, Injury of gastrointestinal tract | Altered Intercellular Communication | Plasma citrulline concentration, as a sign of intestinal injury, and C-reactive protein, orosomucoid, albumin, a(1)-antitrypsin, and haptoglobin, as signs of systemic inflammation, were analyzed. | 20667967 |
| Airway structure, Asthma | Altered Intercellular Communication | Airway inflammation is fundamental to the cause and persistence of asthma and other airway conditions. | 20668016 |
| Airway structure | Altered Intercellular Communication | However, the presence and type of airway inflammation can be difficult to detect clinically, delaying the introduction of appropriate treatment. | 20668016 |
| Airway structure | Altered Intercellular Communication | They can accurately discriminate eosinophilic airway inflammation from noneosinophilic airway inflammation and, thus, help to guide therapy. | 20668016 |
| Airway structure, Inflammation | Altered Intercellular Communication | Eosinophilic airway inflammation is steroid responsive, whereas noneosinophilic (usually neutrophilic) inflammation generally is not. | 20668016 |
| ARCN1 gene, airway disease, Chronic cough, Airway structure, Asthma | Altered Intercellular Communication | Monitoring of airway inflammation using sputum cell counts helps to identify the impending loss of asthma control and, thus, the need to adjust antiinflammatory medications in patients with a variety of airway diseases, such as asthma, smoker's COPD, and chronic cough. | 20668016 |
| Airway structure | Altered Intercellular Communication | Other noninvasive, indirect measurements of airway inflammation, such as exhaled nitric oxide, do not help to identify the cellular nature of airway inflammation associated with exacerbations of airway diseases, particularly in patients who are already on corticosteroids. | 20668016 |
| vascular inflammations | Altered Intercellular Communication | Moreover, a remarkable association of the G82S variant with serum CRP levels implied that the prevalence of RAGE 82S allelic variation might influence susceptibility to CAD by affecting vascular inflammation. | 20668462 |
| Intestinal metaplasia, Gland, Inflammatory disease of mucous membrane | Altered Intercellular Communication | Intestinal metaplasia (IM), glandular atrophy and mucosal inflammation were diagnosed from histological specimens and graded according to the updated Sydney-classification. | 20668939 |
| Inflammation | Altered Intercellular Communication | In contrast, there was more severe active inflammation in the corpus than the antrum (P = 0.017). | 20668939 |
| Inflammation, Neoplasms | Altered Intercellular Communication | Incomplete colonoscopies due to stenosis (78.9 %), severe inflammation (77.8 %) or an obstructing tumor (74.6 %) were most frequently followed by a secondary examination. | 20669092 |
| Aspergillosis | Altered Intercellular Communication | Invasive sino-orbital-skull base aspergillosis often may resemble inflammatory conditions. | 20669647 |
| Inflammation, Hypertension, CTCAE, Diabetes Mellitus | Altered Intercellular Communication | [Effects of tongxinluo capsule on platelet activating and inflammation factors as well as vascular endothelial function in patients with essential hypertension complicated with diabetes mellitus]. | 20669673 |
| vascular inflammations, Demographics Domain | Altered Intercellular Communication | TXLC can inhibit the platelet activation and vascular inflammation response, also improve the vascular endothelial function in patients with EH complicated with DM. | 20669673 |
| Airway structure | Altered Intercellular Communication | Fractional exhaled nitric oxide (FeNO) measurement is a reliable, noninvasive marker of airway inflammation. | 20670207 |
| Airway structure | Altered Intercellular Communication | The use of portable FeNO analyzers may enable the assessment of airway inflammation in primary care. | 20670207 |
| Heart Failure, Systolic | Altered Intercellular Communication | Clinical significance of endogenous vasoactive neurohormones in chronic systolic heart failure. | 20670842 |
| Inflammation, Complication Aspects | Altered Intercellular Communication | Moreover, resistin may induce thrombotic complications via mediating the lipoprotein metabolism and stimulating inflammation. | 20671416 |
| Pain Distress Question, Erythema, Inflammation | Altered Intercellular Communication | After this infusion, the patient complained of pain around the site of injection and presented a 10x6-cm swollen area with erythema and inflammation. | 20671512 |
| Cataract, Inflammation, Hemorrhage | Altered Intercellular Communication | Prompt cataract removal led to resolution of the inflammation, clearing of the anterior chamber haemorrhage, and normalization of intraocular pressure in all four affected eyes. | 20671768 |
| Ocular Hypertension, Uveitis, Traumatic injury, Hyphema, Pathologic Neovascularization | Altered Intercellular Communication | spontaneous hyphaema and acute ocular hypertension can occur in patients with severe lens-induced intraocular inflammation in the absence of trauma or ocular neovascularization. | 20671768 |
| Inflammation | Altered Intercellular Communication | These results strongly suggest that PPARgamma plays a key role in age-related inflammation and may have clinical applications as a molecular target in the treatment of age-related inflammation. | 20672248 |
| ARCN1 gene, Chronic Obstructive Airway Disease | Altered Intercellular Communication | Chronic obstructive pulmonary disease (COPD) itself causes hormonal changes. | 20673032 |
| Intraocular inflammation | Altered Intercellular Communication | This report describes the occurrence of intraocular inflammation after treatment with the TNF-alpha antagonist etanercept. | 20673052 |
| Inflammation, Primary malignant neoplasm, Neoplasms, Carcinoma of lung, Lip and Oral Cavity Carcinoma | Altered Intercellular Communication | Recent advances in understanding complex tumor interactions have led to the discovery of an association between inflammation and cancer, in particular for colon and lung cancer, but only a very few have dealt with oral cancer. | 20673375 |
| Inflammation, Keratitis | Altered Intercellular Communication | Diffuse lamellar keratitis (DLK) is a sterile inflammation after laser in situ keratomileusis. | 20674084 |
| Inflammation | Altered Intercellular Communication | Matrix metalloproteinase (MMP)-9 is involved in both inflammation and matrix degradation and considered a main contributor to coronary plaque rupture. | 20674181 |
| Inflammation, Tumor necrosis, Vascular calcification | Altered Intercellular Communication | Many studies have provided evidence for a role of inflammation and inflammatory cytokines such as tumour necrosis factor (TNF)-a and interleukin (IL)-1b in the vascular calcification process. | 20674184 |
| Inflammation, Ulcerative Colitis | Altered Intercellular Communication | We conclude that elevated serum DcR3 may serve as an indicator of active colonic inflammation in patients with UC. | 20675196 |
| Inflammation, Viral keratitis, Corneal Diseases | Altered Intercellular Communication | The signs of inflammation in corneal layers were detected especially in group of patients classified as viral keratitis but were also found in corneas of patients with degenerative diseases of the cornea. | 20675284 |
| Inflammation | Altered Intercellular Communication | The CT scan showed a thickened gallbladder with adjacent inflammation and a 2-cm pseudo-aneurysm in its wall. | 20675459 |
| Orbital Pseudotumor | Altered Intercellular Communication | To identify risk factors involved in the development of idiopathic orbital inflammation (IOI). | 20675725 |
| Intraocular inflammation | Altered Intercellular Communication | In addition, none of the samples from the control patients without intraocular inflammation were positive. | 20675730 |
| Inflammation, Anastomotic Leak | Altered Intercellular Communication | Anastomotic leakage was associated with patient co-morbidity rather than with intraoperative Hinchey category, suggesting that the decision to perform PA should better be based on patient's general condition rather than on intraoperative extent of inflammation. | 20676663 |
| Inflammation, Malignant Neoplasms | Altered Intercellular Communication | Chronic inflammation has been consistently associated with cancers of several sites, including the breast, and inhibition of inflammation through the use of non-steroidal anti-inflammatory drugs (NSAIDs) has been inversely associated with risk. | 20676755 |
| Autoimmune Diseases, Optic Neuritis | Altered Intercellular Communication | A 41-year-old man presented with left optic neuritis (ON) without evidence of other autoimmune disease or hormonal imbalance. | 20676777 |
| Inflammation, Chronic Kidney Diseases | Altered Intercellular Communication | 3'-Nitrotyrosine (3NT) is a post-translational modification (PTM) of body fluids and tissues that is sustained by chronic inflammation and oxidative stress, two main clinical traits of chronic kidney disease (CKD). | 20676907 |
| Inflammation, Fibrosis Assessment, Hepatitis | Altered Intercellular Communication | Chronic hepatitis had been proved by liver biopsy in the majority of cases and/or biological markers of inflammation and fibrosis. | 20677341 |
| Tolosa-Hunt Syndrome, Inflammation, Orbital fissure | Altered Intercellular Communication | Tolosa-Hunt syndrome is a nonspecific granulomatous inflammation of the cavernous sinus, superior orbital fissure and apex of the orbit. | 20677620 |
| Airway structure | Altered Intercellular Communication | However, in the majority of these subjects airway inflammation is still present when measured. | 20678209 |
| Airway structure | Altered Intercellular Communication | Sputum induction and AMP provocation were previously shown to be sensitive markers of airway inflammation. | 20678209 |
| Inflammation, Asthma | Altered Intercellular Communication | Subjects with complete asthma remission, in contrast to subjects with current asthma, do not respond with eosinophilic inflammation in sputum after AMP provocations. | 20678209 |
| Inflammation, Malignant neoplasm of gallbladder, Carcinoma, Hyperplasia and Metaplasia | Altered Intercellular Communication | The development of gallbladder cancer occurs over a long time (more than 15 y) and evolves from chronic inflammation to dysplasia/metaplasia, carcinoma in situ, and invasive carcinoma. | 20679224 |
| Inflammation | Altered Intercellular Communication | Immunoglobulin (Ig) free light chains (FLCs) are short-lived B cell products that contribute to inflammation in several experimental disease models. | 20679475 |
| Sleep-Disordered Breathing, Inflammation | Altered Intercellular Communication | Sleep-disordered breathing (SDB) is thought to be a state of inflammation caused by hypoxic stress. | 20679736 |
| Vasculitis, Pulmonary Hypertension | Altered Intercellular Communication | Increased platelet, leukocyte and endothelial microparticles predict enhanced coagulation and vascular inflammation in pulmonary hypertension. | 20680403 |
| vascular inflammations, Endothelial dysfunction, Pulmonary Hypertension | Altered Intercellular Communication | Pulmonary hypertension (PH) is associated with platelet activation, vascular inflammation and endothelial dysfunction leading to often life threatening thrombo-embolic complications. | 20680403 |
| Inflammation, Hyperplastic Polyp | Altered Intercellular Communication | PH patients have increased levels of platelet-, leukocyte- and endothelial MP indicating an increased vascular pro-coagulation and inflammation which might be related to thrombo-embolic complications as well as PH progression. | 20680403 |
| Inflammation, Endothelial dysfunction | Altered Intercellular Communication | Biomarkers of inflammation, endothelial dysfunction and insulin resistance in adults of Inner Mongolia, China. | 20680929 |
| Inflammation, Endothelial dysfunction | Altered Intercellular Communication | Low-grade chronic inflammation and endothelial dysfunction have been hypothesized to underlie the constellation of cardiometabolic risk factors, possibly by inducing insulin resistance. | 20680929 |
| Inflammation, Endothelial dysfunction | Altered Intercellular Communication | This study suggests that inflammation and endothelial dysfunction may relate to insulin resistance. | 20680929 |
| Communicable Diseases, Visual Impairment, Inflammation, Infection | Altered Intercellular Communication | Risk factors for visual impairments following bleb-related infections were recurrence of infection (p = 0.022), negative Seidel tests (p = 0.0056), aphakia (p = 0.045), avitreous (p = 0.00070), positive Streptococcus species (p = 0.029), and prolonged inflammation (p = 0.014). | 20681255 |
| Inflammation | Altered Intercellular Communication | The finding that the patient recovered after corticosteroid therapy alone suggests that non-infectious inflammation played a major role in the pathogenesis. | 20681268 |
| Inflammation, Idiopathic hypertrophic pachymeningitis, Cholesteatoma, Ear Inflammation | Altered Intercellular Communication | Chronic inflammation associated with otitis media with cholesteatoma or surgical invasiveness might induce the recurrence of idiopathic hypertrophic pachymeningitis. | 20681268 |
| Inflammation, Periodontal Diseases | Altered Intercellular Communication | Interleukin (IL)-6, a multifunctional cytokine, plays a role in the tissue inflammation that characterizes periodontal disease. | 20682019 |
| Inflammation, Albuminuria | Altered Intercellular Communication | Inflammation, kidney function and albuminuria in the Framingham Offspring cohort. | 20682604 |
| Inflammation, Cyclophosphamide/Vincristine/Dacarbazine Regimen, Chronic Kidney Diseases, Cardiovascular Diseases | Altered Intercellular Communication | Inflammation and chronic kidney disease (CKD) are both associated with cardiovascular disease (CVD). | 20682604 |
| Inflammation, Albuminuria | Altered Intercellular Communication | Biomarkers of inflammation are associated with kidney function and albuminuria. | 20682604 |
| Inflammation, Rheumatoid Arthritis | Altered Intercellular Communication | Are lipid ratios less susceptible to change with systemic inflammation than individual lipid components in patients with rheumatoid arthritis? | 20682616 |
| Refractory anemias, Inflammation, Cyclophosphamide/Vincristine/Dacarbazine Regimen, Cardiovascular Diseases | Altered Intercellular Communication | In summary, the effects of inflammation on individual lipid levels may underestimate lipid-associated cardiovascular disease (CVD) risk in RA, thus lipid ratios may be more appropriate for CVD risk stratification in RA. | 20682616 |
| Inflammation | Altered Intercellular Communication | Interleukin 33 (IL-33) is a novel cytokine involved in joint inflammation in animal models. | 20682660 |
| Refractory anemias, Inflammation | Altered Intercellular Communication | However, no correlation was found between IL-33 concentration and acute-phase inflammation reactant or the score of the Disease Activity Index, suggesting a complex or indirect character of the link between IL-33 and the inflammation in RA. | 20682660 |
| Inflammation | Altered Intercellular Communication | C-C chemokine receptor 5 (CCR5) plays an important role in inflammation. | 20682662 |
| Gastrointestinal inflammation | Altered Intercellular Communication | However, the role of MBL in intestinal inflammation is currently unclear. | 20682699 |
| Inflammation | Altered Intercellular Communication | These results suggest that systemic MBL helps to prevent excessive inflammation upon access of normally mild pathogens across the damaged intestinal epithelium. | 20682699 |
| Communicable Diseases, Inflammation | Altered Intercellular Communication | The specificity of Tc-UBI for localizing infection foci and for discarding sterile inflammation was 95.35%, the sensitivity was 97.52%, the positive predictive value was 96.72%, the negative predictive value was 96.47%, the accuracy was 96.62%, and the observed agreement between the bacterial culture and the molecular image was 96.62% (P=0.0001). | 20683364 |
| Communicable Diseases, Inflammation | Altered Intercellular Communication | Considering that the absolute and relative frequencies are very high, we propose that, in the future, Tc-UBI molecular imaging could be the gold standard to detect infection sites and to discard sterile inflammation. | 20683364 |
| Fever, Fever of Unknown Origin, Fever, CTCAE, Bacterial Infections | Altered Intercellular Communication | Fever of unknown origin (FUO) represents a challenge to clinical medicine, and bacterial cultures have been considered the 'gold standard' in discriminating between fevers resulting from bacterial infection and sterile inflammations. | 20683364 |
| Inflammation, Sarcopenia, Malnutrition, Chronic disease | Altered Intercellular Communication | The causes of sarcopenia are multi-factorial and can include disuse, changing hormonal function, chronic diseases, inflammation, insulin resistance, and nutritional deficiencies. | 20683658 |
| Inflammation, Sarcopenia, Malnutrition, Chronic disease | Altered Intercellular Communication | The causes of sarcopenia are multi-factorial and can include disuse, changing hormonal function, chronic diseases, inflammation, insulin resistance, and nutritional deficiencies. | 20683658 |
| Inflammation | Altered Intercellular Communication | Only lobular inflammation improved significantly (P for the modified Brunt score = 0.011, P for NAS = 0.005). | 20683947 |
| Inflammation, Hypertension, CTCAE, Overweight | Altered Intercellular Communication | In subgroup analyses, significant improvements in lobular inflammation were also observed in males, younger patients up to 50 years of age, slightly overweight patients, and patients with hypertension and an increased histology score. | 20683947 |
| Inflammation, Fibrosis Assessment, Fatty degeneration, Diabetes Mellitus, Non-alcoholic Fatty Liver Disease | Altered Intercellular Communication | After adjustment for age, sex, diabetes, and alcohol consumption, the minor allele of rs738409 C/G, a nonsynonymous coding SNP in the patatin-like phospholipase domain-containing protein 3 (PNPLA3) (adiponutrin) gene encoding an Ile148Met change, was associated with steatosis (P = 0.03), portal inflammation (P = 2.5 x 10(-4)), lobular inflammation (P = 0.005), Mallory-Denk bodies (P = 0.015), NAFLD activity score (NAS, P = 0.004), and fibrosis (P = 7.7 x 10(-6)). | 20684021 |
| Inflammation, Vasculitis, CTCAE | Altered Intercellular Communication | Vasculitis may cause inflammation in any single or group of blood vessels. | 20685065 |
| Autoimmune Diseases, vascular inflammations | Altered Intercellular Communication | Serum levels of adhesion molecules ICAM-1 and VCAM-1 and tissue inhibitor of metalloproteinases, TIMP-1, are elevated in patients with autoimmune thyroid disorders: relevance to vascular inflammation. | 20685094 |
| Autoimmune Diseases, Inflammation, Atherosclerosis | Altered Intercellular Communication | The physiopathological link between inflammation, atherosclerosis and autoimmunity is well demonstrated. | 20685094 |
| Inflammation | Altered Intercellular Communication | Inflammation contributes to axon reflex vasodilatation evoked by iontophoresis of an a-1 adrenoceptor agonist. | 20685182 |
| Lupus Erythematosus | Altered Intercellular Communication | We propose that development of systemic lupus erythematosus in this case may have been due to low grade chronic inflammation. | 20685593 |
| Inflammation, Carcinoma, Squamous intraepithelial lesion, Cervical Intraepithelial Neoplasia | Altered Intercellular Communication | The amplification of hTERC showed 6.06% in normal or inflammation cases, 10.00% in CIN 1, 66.67% in CIN 2, 72.50% in CIN 3, and 100.00% in carcinoma, with significant difference between the low- (or=CIN 2 or >or=atypical squamous cells in which high-grade squamous intraepithelial lesion cannot be excluded) cervical lesions (P < 0.001). | 20686384 |
| Inflammation, Ischemic stroke, Cardiovascular Diseases | Altered Intercellular Communication | C-reactive protein (CRP) is one of the acute-phase proteins produced predominantly by hepatocytes in response to inflammation, and it has been widely reported that CRP genetic polymorphism is a risk factor for cardiovascular disease and ischemic stroke. | 20686879 |
| Esophagitis | Altered Intercellular Communication | The endoscopic recognition of linear furrows, concentric rings, and white exudates is important in the diagnosis of eosinophilic esophageal inflammation. | 20686904 |
| Inflammation, Acute peritonitis | Altered Intercellular Communication | These values were compared in group of 52 patients with acute peritonitis against group of 39 patients without inflammation within peritoneal cavity. | 20687377 |
| Inflammation, Iron deficiency anemia | Altered Intercellular Communication | Acute intraabdominal inflammation induced in all patients a state of hypoferremia. | 20687377 |
| Necrotizing granulomatous inflammation, Neoplasms, Pneumonia | Altered Intercellular Communication | The most common specific diagnoses were necrotizing granulomatous inflammation (45), scar (28), organizing pneumonia (13), and benign neoplasms (11). | 20688352 |
| Inflammation, Interstitial Fibrosis Assessment | Altered Intercellular Communication | A mixture of interstitial fibrosis and chronic inflammation (16) was the most common nonspecific diagnosis. | 20688352 |
| Inflammation, Fibrosis Assessment, Malignant Neoplasms | Altered Intercellular Communication | Malignancy was diagnosed on a subsequent biopsy in only one case, and the initial biopsy in that case showed non-specific chronic inflammation and fibrosis. | 20688352 |
| Inflammation, Prostate carcinoma | Altered Intercellular Communication | Recent interest has focused on the role that inflammation may play in the development of prostate cancer and whether use of aspirin or other nonsteroidal antiinflammatory drugs (NSAIDs) affects risk. | 20688905 |
| Inflammation, Vascular System Injuries | Altered Intercellular Communication | Inhibition of p38 mitogen-activated protein kinase reduces inflammation after coronary vascular injury in humans. | 20689074 |
| Inflammation, Cerebrovascular Trauma, Myocardial | Altered Intercellular Communication | Coronary artery stents provide benefit by maintaining lumen patency but may incur vascular trauma and inflammation, leading to myocardial damage. | 20689074 |
| Inflammation, Atrial thrombosis | Altered Intercellular Communication | Although systemic inflammation is a known predictor of left atrial thrombus formation in patients with nonrheumatic AF, the relation between the CHADS2 score and systemic inflammation is unknown. | 20691312 |
| Inflammation, Atrial thrombosis | Altered Intercellular Communication | In conclusion, in patients with nonrheumatic AF, CHADS2 score is related to systemic inflammation, left atrial thrombus formation, and prognosis. | 20691312 |
| Inflammation, Fibrosis Assessment, Lacrimation | Altered Intercellular Communication | Increasing knowledge about this syndrome, including better imaging, has facilitated patient treatment for a stable spectrum of rotator cuff pathology (inflammation or fibrosis, partial-thickness tearing, full-thickness tearing undergoing debridement), as has the application of endoscopic surgery. | 20691562 |
| Inflammation, Diabetes Mellitus, Atherosclerosis | Altered Intercellular Communication | Diabetes is associated with low-grade inflammation, which has an important role in the development of atherosclerosis. | 20691708 |
| Inflammation, Diabetes Mellitus, Atherosclerosis | Altered Intercellular Communication | Currently, we followed diabetes patients to investigate, if the Pro7 allele is associated with the inflammation related to atherosclerosis. | 20691708 |
| Inflammation, Refractory anemias, Degenerative polyarthritis, Rheumatoid Arthritis, Tumor necrosis, Interphalangeal joint structure | Altered Intercellular Communication | To investigate the association between systemic and local inflammation and incident and progressive radiographic secondary osteoarthritis (OA) in interphalangeal joints (IPJs) over 3 years in rheumatoid arthritis (RA) patients and the effect of tumor necrosis factor alpha (TNF-a) inhibitor infliximab on secondary OA in IPJs. | 20691795 |
| Degenerative polyarthritis, Inflammation | Altered Intercellular Communication | Infliximab treatment was associated with lower incident secondary OA in PIPJs [relative risk 0.5 (95% confidence interval 0.2, 1.0)], independent of decrease in inflammation. | 20691795 |
| Degenerative polyarthritis, Inflammation | Altered Intercellular Communication | Infliximab treatment reduced incident secondary OA in PIPJs independent of decrease in inflammation, suggesting that anti-TNF-a therapy might be effective against secondary hand OA via other pathways than suppression of inflammation. | 20691795 |
| HD Term Type, Malnutrition, Inflammation, Atherosclerosis | Altered Intercellular Communication | Difficulty healing wounds and skin defects is a frequent problem in patients on chronic hemodialysis (HD) because of malnutrition, inflammation, and atherosclerosis (MIA) syndrome. | 20692601 |
| Malnutrition, HD Term Type, Inflammation | Altered Intercellular Communication | The apparent malnutrition and inflammation in HD patients are likely responsible for the decreased skin blood flow and the development of the difficulty to heal skin defects and wounds. | 20692601 |
| Inflammation, Prostate carcinoma | Altered Intercellular Communication | High intake of n-6 fatty acids, through their effects on inflammation and oxidative stress, may increase prostate cancer risk. | 20693267 |
| Inflammatory abnormality of the eye | Altered Intercellular Communication | The corresponding rates for all ocular inflammation were 450 and 467/100,000. | 20693551 |
| Inflammatory abnormality of the eye, Infectious Endophthalmitis, Uveitis | Altered Intercellular Communication | The majority of cases of posterior uveitis and infectious endophthalmitis were visually compromised, but few among the cases of other forms of ocular inflammation were visually impaired. | 20693551 |
| Inflammatory abnormality of the eye, Traumatic injury | Altered Intercellular Communication | The results suggest that nearly one in 200 persons in rural, South India has been affected by ocular inflammation in at least one eye by mid to late adulthood, about one in 330 if cases related to surgery or trauma are not included. | 20693551 |
| Inflammation, Hypermetabolism, Burn injury | Altered Intercellular Communication | Girls also have less inflammation and hypermetabolism after major burns. | 20693914 |
| abdominal sepsis, Inflammation | Altered Intercellular Communication | Edema and inflammation due to abdominal sepsis can prevent the use of standard management (i.e., colostomy, ileostomy or Hartmann's procedure), in which case alternative salvage repair methods are required. | 20694495 |
| Sleep-Disordered Breathing, Inflammation | Altered Intercellular Communication | SDB has a high prevalence in CAD patients and seems to be associated with chronic inflammation, which may be linked to CAD progression and/or acute coronary events. | 20694765 |
| Inflammation, Cardiovascular Diseases, Atherosclerosis | Altered Intercellular Communication | Inflammation and oxidative stress are associated with cardiovascular diseases and underlying atherosclerosis. | 20695884 |
| Refractory anemias, Inflammation, Damage | Altered Intercellular Communication | Treatment strategies for RA have improved dramatically over the last decades, resulting in less inflammation and joint damage. | 20696679 |
| Inflammation | Altered Intercellular Communication | Reduction of the PaO2/FiO2 ratio in acute aortic dissection - relationship between the extent of dissection and inflammation -. | 20697178 |
| Inflammation | Altered Intercellular Communication | The process of healing of chronic periapical inflammation lasted longer in patients aged 45-78 years than in patients aged 17-44 years. | 20698178 |
| Inflammation, Malignant Neoplasms | Altered Intercellular Communication | The resected specimens were examined histopathologically to determine the degree of inflammation and the presence of malignancy. | 20698210 |
| Inflammation, Arthritis, Gouty | Altered Intercellular Communication | To relate the expression of the matrix degrading proteinase cathepsin B and its endogenous inhibitor cystatin C in the synovial fluid (SF) to the clinical and laboratory variables of joint inflammation in gouty arthritis of the knee. | 20699092 |
| Inflammation, Gout | Altered Intercellular Communication | These results show a high correlation between the cathepsin B/cystatin C system and markers of joint inflammation in acute gout of the knee, demonstrating the pathologic role of cathepsin B and cystatin C in inflammation. | 20699092 |
| Hypoglycemia, Neuroglycopenia | Altered Intercellular Communication | This increased vulnerability may be due to more symptom "noise" (more symptoms during euglycemia), making it harder to detect hypoglycemia while driving; possibly greater carbohydrate utilization, rendering them more vulnerable to experiencing hypoglycemia; less hormonal counterregulation, leading to more profound hypoglycemia; and more neuroglycopenia, rendering them more vulnerable to impaired driving. | 20699432 |
| Inflammation, Fibrosis Assessment, Fatty degeneration, Fatty Liver Disease | Altered Intercellular Communication | The mean ALT (P = 0.012), SAP (P = 0.003), serum bilirubin (P = 0.001), AST/ALT ratio (P = 0.03), steatosis (P < 0.001), ballooning degeneration of hepatocytes (P < 0.001), portal inflammation (P < 0.001), Mallory hyaline (P = 0.001), ductular proliferation and fibrosis (P < 0.001) showed a significant difference between ASH and NASH cases. | 20699492 |
| Fibrosis Assessment, Portal inflammation, Cholestasis, Balloon Dilatation | Altered Intercellular Communication | Older age, male sex, larger derangement of serum biochemistry, high serum bilirubin, AST/ALT > 1, more ballooning degeneration, portal inflammation, Mallory's hyaline, hepatocytic and ductular cholestasis, ductular proliferation and higher stage of fibrosis favors a diagnosis of ASH. | 20699492 |
| Inflammation, Fatty degeneration, Fatty Liver Disease | Altered Intercellular Communication | Younger age, high ALT, AST/ALT < 1, higher grade of steatosis and absence of extensive neutrophilic portal inflammation favors a diagnosis of NASH. | 20699492 |
| Inflammation, Ischemia | Altered Intercellular Communication | High-mobility group protein box-1 (HMGB1) has recently been recognized as a novel candidate in a specific upstream pathway promoting inflammation after brain ischemia. | 20700129 |
| Inflammation, Squamous cell carcinoma, SERPINB3 wt Allele | Altered Intercellular Communication | To study the main processes involved in oral squamous cell carcinoma (OSCC): apoptosis and inflammation. | 20701075 |
| glycation, vascular inflammations | Altered Intercellular Communication | The receptor for advanced glycation endproducts (RAGE) regulates vascular inflammation and atherogenesis. | 20701913 |
| Inflammatory abnormality of the eye, Ocular syphilis | Altered Intercellular Communication | All patients with ocular syphilis exhibited functional improvement and resolution of ocular inflammation after a specific antibiotic treatment. | 20703496 |
| Inflammation, Fibrosis Assessment, Lymphoid hyperplasia | Altered Intercellular Communication | Pathologic examination revealed chronic inflammation (n= 178), fibrosis without inflammation (n= 19), normal mucosa (n= 4), and lymphoid hyperplasia (n= 1). | 20704489 |
| Carcinoma, Basosquamous, Granulomatous inflammation, Chronic leukemia (category), Lymphoproliferative Disorders | Altered Intercellular Communication | Three patients had abnormal pathology: Lymphoproliferative disease in the patient with chronic leukemia, granulomatous inflammation, and basosquamous cell carcinoma. | 20704489 |
| vascular inflammations | Altered Intercellular Communication | Imaging of vascular inflammation with [11C]-PK11195 and positron emission tomography/computed tomography angiography. | 20705222 |
| vascular inflammations | Altered Intercellular Communication | By binding to activated macrophages in the vessel wall, [11C]-PK11195 enables noninvasive imaging of vascular inflammation. | 20705222 |
| Keratitis, Corneal edema | Altered Intercellular Communication | Besides central corneal edema, no other signs of corneal inflammation were detected. | 20705342 |
| Inflammation, Overweight | Altered Intercellular Communication | Chronic inflammation is associated with overweight in Colombian school children. | 20705440 |
| Inflammation, Periodontitis, Gingival Hemorrhage | Altered Intercellular Communication | Periodontal disease markers (extent of gingival bleeding, pocket depth, and loss of attachment, and a case definition of periodontitis) were associated on the arterial blood pressure outcomes through a series of regression models, incrementally adjusting for confounders (demographic, inflammation markers, chronic conditions, smoking, BMI, socio-economic status). | 20706132 |
| Inflammation, Hypertension, CTCAE, Gingival Hemorrhage | Altered Intercellular Communication | Gingival bleeding, a marker of current periodontal inflammation, was the only measure consistently and significantly associated with raised SBP and an increased odds of hypertension in the US adult population throughout the adjustment process. | 20706132 |
| Inflammatory, Inflammation | Altered Intercellular Communication | Spastic inflammatory entropion disappears with successful treatment of the inflammation. | 20706724 |
| Cicatricial entropion, Inflammation, Traumatic injury | Altered Intercellular Communication | Finally, cicatricial entropion can occur as a consequence of persistent inflammation or injuries. | 20706724 |
| Cessation of life, Inflammation, Atherosclerotic lesion | Altered Intercellular Communication | Besides the inflammation, the Fas/Fas ligand (FasL)/caspase death pathway is documented to be activated in atherosclerotic lesions. | 20707047 |
| Inflammation | Altered Intercellular Communication | [Chronic low-grade inflammation, lipid risk factors and mortality in functionally dependent elderly]. | 20707051 |
| Airway structure, ARCN1 gene, Chronic Obstructive Airway Disease | Altered Intercellular Communication | The fact that cytokines have the ability to induce its synthesis and release, creates a dynamic loop for self-preservation and augmentation of the airway inflammation in Chronic Obstructive Pulmonary Disease (COPD), even after the ceasing of the noxious stimulus, i.e., cigarette smoke. | 20707291 |
| Inflammation, Atherosclerotic lesion | Altered Intercellular Communication | Inflammation plays an essential role in the development and progression of atherosclerotic lesions. | 20709104 |
| Airway structure, Asthma | Altered Intercellular Communication | Studies using allergen challenge models have suggested Th2 cytokines promote airway inflammation in asthma. | 20709516 |
| Airway structure, Asthma | Altered Intercellular Communication | We assessed mediators of airway inflammation during the chronic asymptomatic phase of asthma. | 20709516 |
| Airway structure, Inflammation, Asthma | Altered Intercellular Communication | Baseline airway inflammation of intrinsic and extrinsic asthma is characterized by eosinophilic inflammation and the Th1 cytokine, IFN-gamma. | 20709516 |
| Vasculitis | Altered Intercellular Communication | Recent evidence suggests that chronic vascular inflammation ensues as an imbalance between pro- and anti-inflammatory mediators. | 20709806 |
| Inflammation | Altered Intercellular Communication | Recently identified lipid mediators (eg, lipoxins and resolvins) play active roles in promoting the resolution of inflammation. | 20709806 |
| Peripheral Arterial Diseases, Vascular System Injuries | Altered Intercellular Communication | These results also suggest that peripheral artery disease is associated with an inflammation-resolution deficit and highlight a potential therapeutic opportunity for the regulation of vascular injury responses. | 20709806 |
| Skin Papule, Staphylococcus, coagulase positive | Altered Intercellular Communication | Staphylococcus coagulase-positive skin inflammation associated with epidermal growth factor receptor-targeted therapy: an early and a late phase of papulopustular eruptions. | 20709888 |
| Rheumatoid Arthritis, Inflammation, Torticollis | Altered Intercellular Communication | Torticollis due to acute rheumatoid arthritis or other inflammation around the neck. | 20711828 |
| Inflammation, Osteopenia | Altered Intercellular Communication | In the 36-month observation period, there were no incidences of implant failure, excessive bone loss around implants, or peri-implant inflammation. | 20712440 |
| Inflammation, Precocious atherosclerosis, Cardiovascular Diseases, Refractory anemias, Cyclophosphamide/Vincristine/Dacarbazine Regimen, Endothelial dysfunction | Altered Intercellular Communication | In this study we aimed to investigate whether there are indications of premature atherosclerosis, as measured by endothelial dependent flow-mediated dilation (ED-FMD) and intima media thickness (IMT), in patients with very early RA, and to analyze its relation to biomarkers of endothelial dysfunction, taking inflammation and traditional cardiovascular disease (CVD) risk factors into account. | 20712865 |
| Inflammation, Hypoxia, Obesity | Altered Intercellular Communication | Regional differences among adipose depots in capacities for fatty acid storage, susceptibility to hypoxia, and inflammation likely contribute to complications of obesity. | 20713685 |
| Inflammation, Hypoxia | Altered Intercellular Communication | VAT-EC may contribute to hypoxia and inflammation in VAT. | 20713685 |
| Pulmonary arterial hypertension, Inflammation, Polycyclic Hydrocarbons, Aromatic | Altered Intercellular Communication | Inflammation is a feature of pulmonary arterial hypertension (PAH), and increased circulating levels of cytokines are reported in patients with PAH. | 20713898 |
| Intraocular inflammation, Uveitis | Altered Intercellular Communication | 56 eyes of 44 patients with intraocular inflammation were consecutively recruited from the uveitis clinic over 9 months. | 20714184 |
| Intraocular inflammation, Panuveitis, Uveitis | Altered Intercellular Communication | The degree of intraocular inflammation was recorded according to the Standardization of Uveitis Nomenclature criteria and the eyes were grouped as having anterior, intermediate, posterior or panuveitis. | 20714184 |
| Dyspnea, Bronchitis | Altered Intercellular Communication | Acute exacerbations of chronic bronchitis (AECB) are defined as recurrent attacks of worsening bronchial inflammation that are marked by an increase in the volume of daily sputum produced, a change in color of the expectorated sputum, and worsening dyspnea. | 20714379 |
| Vascular Diseases, vascular inflammations, Mitochondrial abnormalities | Altered Intercellular Communication | This review focuses on mitochondrial abnormalities that occur in the vasculature during aging and explores the link between mitochondrial oxidative stress, chronic low-grade vascular inflammation, increased rate of endothelial apoptosis, and development of vascular diseases in the elderly. | 20714704 |
| Inflammation, Pathology | Altered Intercellular Communication | NADPH oxidase/dual-oxidase (Nox/Duox) family members have been implicated in nuclear factor kappa-B (NFkB)-mediated inflammation and inflammation-associated pathologies. | 20715105 |
| Orbital Pseudotumor | Altered Intercellular Communication | The authors describe 2 cases of orbital xanthogranulomatous disease associated with an increase in IgG4-positive plasma cells, and also examine IgG4 in other types of orbital inflammation. | 20716008 |
| Necrobiotic Xanthogranuloma, Lipogranuloma, Mycoses, Orbital Pseudotumor, Chronic dacryoadenitis | Altered Intercellular Communication | Immunohistochemistry for total IgG and IgG4 was performed in 18 cases of orbital inflammation, including chronic dacryoadenitis (n=10), necrobiotic xanthogranuloma (n=2), xanthogranuloma (n=1), idiopathic orbital inflammation/pseudotumor (n=4), and fungal infection (n=1). | 20716008 |
| Rheumatoid Arthritis, Inflammation | Altered Intercellular Communication | Detection of hydrogen sulfide in plasma and knee-joint synovial fluid from rheumatoid arthritis patients: relation to clinical and laboratory measures of inflammation. | 20716297 |
| Inflammation, Swelling | Altered Intercellular Communication | Pharmacological inhibition of H(2)S synthesis reduces inflammation and swelling, suggesting that H(2)S is a potential inflammatory mediator. | 20716297 |
| Inflammation | Altered Intercellular Communication | SF H(2)S levels correlated with clinical indices of disease activity (tender joint count, r= 0.651; P < 0.05) and markers of chronic inflammation; Europhile count (r=-0.566; P < 0.01) and total white cell count (r=-0.703; P < 0.01). | 20716297 |
| Inflammation, Cardiovascular Diseases | Altered Intercellular Communication | C-reactive protein (CRP), a biomarker of inflammation, has been associated with increased risk of developing cardiovascular disease. | 20716378 |
| Communicable Diseases, Epithelial cell abnormality, Inflammation | Altered Intercellular Communication | According to the revised Bethesda system, epithelial cell abnormality was found in 7 (2.9%), inflammation in 55 (22.8%), and infection in 9 (3.7%) patients. | 20716829 |
| Primary malignant neoplasm | Altered Intercellular Communication | The relationship between the presence and site of cancer, an inflammation-based prognostic score and biochemical parameters. | 20717110 |
| Primary malignant neoplasm | Altered Intercellular Communication | Therefore, to definitively examine the interrelationships between the above biochemical parameters, the mGPS and the presence of cancer, the Glasgow Inflammation Outcome Study was undertaken. | 20717110 |
| Inflammation, Malignant neoplasm of ovary, Neoplasms | Altered Intercellular Communication | These findings demonstrate that in ovarian carcinomas the unspecific "cancer-related inflammation" contributes to a significant subversion of the adaptive antitumor immune defense mounted at the tumor site. | 20717669 |
| Inflammation, Carcinogenesis | Altered Intercellular Communication | Chronic inflammation and subsequent tissutal alterations may play a key role in prostate carcinogenesis. | 20717995 |
| Primary malignant neoplasm | Altered Intercellular Communication | In this way, molecular alterations of the suppressor of cytokine signaling 3 (SOCS3), one of the most important inhibitory molecule of inflammatory signal transduction circuitries, could contribute to explain the pleiotropic role of interleukin-6 (IL-6) in this type of cancer. | 20717995 |
| Inflammation, Transmural, Hypertrophy | Altered Intercellular Communication | Light microscopic histopathologic analysis revealed acute greater than chronic inflammation, transmural edema, ischemia/necrosis of the intussusceptum, and hypertrophy of the intussuscipiens. | 20718327 |
| Inflammation, Nasopharyngeal carcinoma, Breast Carcinoma Metastatic in Lymph Node | Altered Intercellular Communication | To investigate the f variant of Epstein-Barr virus (EBV) in nasopharyngeal carcinogenesis, we detected the f variant in primary nasopharyngeal carcinoma (NPC), metastatic carcinoma of the lymph node (LN), and chronic inflammation of the nasopharynx from the Guangdong region. | 20718717 |
| Inflammation | Altered Intercellular Communication | However, only one demonstrated the F/f variant in 50 cases of chronic inflammation of the nasopharynx. | 20718717 |
| Nephritis, Lupus Nephritis | Altered Intercellular Communication | Together, these findings indicated that uMSCs were effective in decreasing renal inflammation and alleviating experimental lupus nephritis by inhibiting lymphocytes, inducing polarization of Th2 cytokines, and inhibition of proinflammatory cytokines production rather than direct engraftment and differentiating into renal tissue. | 20719085 |
| Inflammation, Sample Size Calculation, Arthropathy | Altered Intercellular Communication | Arthropathy, particularly synovial inflammation in SSc, is not well characterized. | 20719883 |
| Arthralgia, Inflammation, Sample Size Calculation | Altered Intercellular Communication | We explored the role of MRI and musculoskeletal ultrasonography (MSUS) in detecting and characterizing synovial inflammation in SSc patients with arthralgia while comparing the two imaging modalities. | 20719883 |
| Inflammation, Sample Size Calculation | Altered Intercellular Communication | While both MRI and MSUS are useful in characterizing synovial inflammation in SSc, MRI is clearly more sensitive than MSUS in this setting. | 20719883 |
| Inflammation, Chronic Obstructive Airway Disease | Altered Intercellular Communication | Excessive aortic inflammation in chronic obstructive pulmonary disease: an 18F-FDG PET pilot study. | 20720052 |
| ARCN1 gene, vascular inflammations | Altered Intercellular Communication | We measured vascular inflammation in both COPD patients and controls using (18)F-FDG PET/CT. | 20720052 |
| ARCN1 gene, Inflammation, Metabolic Syndrome X | Altered Intercellular Communication | Aortic inflammation was expressed as the target-to-background ratio (TBR) of the standardized uptake value in 7 COPD patients, 5 metabolic syndrome patients, and 7 ex-smokers. | 20720052 |
| ARCN1 gene, Inflammation, Metabolic Syndrome X | Altered Intercellular Communication | COPD patients exhibited aortic inflammation that fell between the aortic inflammation exhibited by ex-smokers and that by metabolic syndrome patients. | 20720052 |
| Acute inflammation of orbit | Altered Intercellular Communication | There were 530 cases admitted with acute orbital inflammation over a 9-year period from 1 July 2000 to 30 June 2009. | 20720603 |
| Refractory anemias, Communicable Diseases, musculoskeletal infection | Altered Intercellular Communication | The usefulness of neutrophil CD64 expression (CD64) to diagnose local musculoskeletal infection (local infection) and discriminate local infection from RA-related inflammation in RA patients was examined. | 20721724 |
| Refractory anemias, Communicable Diseases, High Affinity Immunoglobulin Gamma Fc Receptor I, human | Altered Intercellular Communication | CD64 is a useful marker in RA patients to discriminate local infection from RA-related inflammation. | 20721724 |
| Inflammation | Altered Intercellular Communication | However, subsequent examination revealed a chronic IgG4-associated, lymphoplasmatic sclerosing inflammation of the biliary tract. | 20721841 |
| vascular inflammations, Leucocytic infiltrate | Altered Intercellular Communication | The severity of inflammatory cell infiltration around the fascial and intramuscular small blood vessels was evaluated using the total vascular inflammation score (TVIS). | 20722021 |
| Inflammation, "Crohns disease of large bowel | Altered Intercellular Communication | Which magnetic resonance imaging findings accurately evaluate inflammation in small bowel Crohn's disease? | 20722053 |
| Inflammation, Fibrosis Assessment | Altered Intercellular Communication | The inflammation score correlated with the fibrosis score (r = 0.63, P = 0.0001). | 20722053 |
| Inflammation, Fibrosis Assessment | Altered Intercellular Communication | We also showed that fibrosis was closely and positively related to inflammation. | 20722053 |
| Inflammation, Fatigue | Altered Intercellular Communication | Mechanisms probably contributing to fatigue in older adults include decline in mitochondrial function, alterations in brain neurotransmitters, oxidative stress, and inflammation. | 20722821 |
| Inflammation, Fatigue | Altered Intercellular Communication | Mechanisms probably contributing to fatigue in older adults include decline in mitochondrial function, alterations in brain neurotransmitters, oxidative stress, and inflammation. | 20722821 |
| Inflammation, Eustachian tube disorder | Altered Intercellular Communication | For long-term success in implantation of the IHA, careful control of middle ear inflammation and measures against eustachian tube dysfunction are required in addition to technological advancements. | 20723782 |
| Inflammation | Altered Intercellular Communication | PFS is characterised in its early stages by local inflammation with beginning ulceration and can be managed conservatively. | 20724234 |
| APP gene, Inflammation | Altered Intercellular Communication | Lower extremity exercise improves aortic hemodynamics and reduces inflammation, but the safety and efficacy of exercise training in AAA disease is unknown. | 20724934 |
| Inflammation, Adrenal Gland Hyperfunction, Cardiovascular Diseases | Altered Intercellular Communication | The frailty syndrome is associated with inflammation, hypercortisolemia, and cardiovascular diseases, all of which are linked with insulin resistance. | 20725120 |
| Hypermetabolism, Inflammation, Weight decreased, Adrenal Gland Hyperfunction | Altered Intercellular Communication | We wondered whether hypermetabolism associated with inflammation and hypercortisolemia could increase the thermic effect of food (TEF) and contribute to the frailty-associated body weight loss. | 20725120 |
| Airway structure, Chronic Obstructive Airway Disease | Altered Intercellular Communication | Relevance of lower airway bacterial colonization, airway inflammation, and pulmonary function in the stable stage of chronic obstructive pulmonary disease. | 20725845 |
| Airway structure, ARCN1 gene, Chronic Obstructive Airway Disease, Active Breathing Control | Altered Intercellular Communication | The objective of this investigation was to verify the hypothesis that the presence of lower airway bacterial colonization (LABC) can be a stimulating factor of airway inflammation, more frequent exacerbation, and impact on pulmonary function, independent of current tobacco smoking in the stable phase of chronic obstructive pulmonary disease (COPD). | 20725845 |
| ARCN1 gene, Active Breathing Control, Airway structure | Altered Intercellular Communication | LABC was documented in a subpopulation of stable COPD patients; it may be responsible for the deterioration of pulmonary function of COPD patients by promoting airway inflammation and/or increased frequency of exacerbations independently of tobacco smoking. | 20725845 |
| Inflammation, Fibrosis Assessment | Altered Intercellular Communication | Intra-operative findings consisted in both cases in tumor-like appendiceal abscesses, situated behind ileocecal junction, with local inflammation and fibrosis, suggesting a long-term evolution. | 20726309 |
| Inflammation | Altered Intercellular Communication | CC chemokine receptors (CCR) have an important role in the recruitment of leukocytes to the site of inflammation. | 20726319 |
| Colorectal Carcinoma, Neoplasms | Altered Intercellular Communication | Toll-like receptor (TLR) 7 and TLR8 expression on CD133+ cells in colorectal cancer points to a specific role for inflammation-induced TLRs in tumourigenesis and tumour progression. | 20728343 |
| Inflammation, Primary malignant neoplasm, Carcinogenesis | Altered Intercellular Communication | Toll-like receptor (TLR) stimulation results in activation of NF-kB, a key modulator in driving inflammation to cancer and mitogen-activated protein kinases that have been shown to recruit mitotic and cyclooxygenase-2 (COX-2) induced pathways in carcinogenesis. | 20728343 |
| Coinfection, Periodontitis, Gram Negative Bacteria | Altered Intercellular Communication | Apical periodontitis is a polymicrobial inflammation with a dominant flora of opportunistic Gram-negative bacteria; however, a pathogenic role of human herpesviruses such as Epstein-Barr virus (EBV) and human cytomegalovirus (HCMV) has been implicated recently. | 20728714 |
| Inflammation, platelet dysfunction | Altered Intercellular Communication | Furthermore, a state of low-grade chronic inflammation can promote increased oxidative stress and lead to endothelial cell and platelet dysfunction ultimately contributing to thrombogenesis. | 20728920 |
| Inflammation, Acute Kidney Insufficiency | Altered Intercellular Communication | Complications associated with mortality included: acute renal impairment (OR 3.3 (95% CI 2.1-5.0), p < 0.001); unplanned Intensive Care Unit admission (OR 3.1 (95% CI 1.9-4.9), p < 0.001); and systemic inflammation (OR 2.5 (95% CI 1.7-3.7), p < 0.001). | 20731639 |
| Hepatitis, Chronic | Altered Intercellular Communication | This would facilitate a fast response, probably controlled by IL-6, against repeated bacterial-DNA translocation or in liver chronic inflammation. | 20731703 |
| ARCN1 gene, Inflammation, Chronic Obstructive Airway Disease | Altered Intercellular Communication | Chronic obstructive pulmonary disease (COPD) may be related to chronic inflammation and immune-mediated conditions, and its pathogenesis involves T-cell activation and proliferation. | 20732370 |
| Inflammation, Periodontal Diseases, Atherosclerosis | Altered Intercellular Communication | The link between periodontal disease and atherosclerosis has not yet been clarified, though systemic inflammation seems to be the common soil for both conditions. | 20732683 |
| Inflammation, Exanthema | Altered Intercellular Communication | We found a lower inhibition of epidermal kinetics and decreased inflammation in HER1/2i-induced rash. | 20732960 |
| Inflammation | Altered Intercellular Communication | Increased levels of inflammation among women with enlarged waist and elevated triglyceride concentrations. | 20733290 |
| Inflammation, Endothelial dysfunction | Altered Intercellular Communication | We have evaluated the association between hypertriglyceridemic waist (HW) phenotype, markers of systemic inflammation and endothelial dysfunction in women. | 20733290 |
| Inflammation, Endothelial dysfunction | Altered Intercellular Communication | This study provides evidence showing a positive association between HW phenotype and markers of systemic inflammation and endothelial dysfunction. | 20733290 |
| Cessation of life, Inflammation | Altered Intercellular Communication | Does association with volume status and inflammation account for the increased death risk from high peritoneal protein clearance in peritoneal dialysis? | 20733298 |
| Inflammation, Fluid overload | Altered Intercellular Communication | To determine if the association between high peritoneal protein clearance (PrC) and increased all-cause mortality is explained by inflammation and volume overload in continuous ambulatory peritoneal dialysis patients. | 20733298 |
| Inflammation, Fluid overload | Altered Intercellular Communication | A high PrC was associated with more severe inflammation and volume overload. | 20733298 |
| Inflammation, Fluid overload | Altered Intercellular Communication | Peritoneal PrC, although correlated with volume overload and inflammation, is largely an independent predictor of mortality. | 20733298 |
| Delirium, Cessation of life | Altered Intercellular Communication | The effect of delirium on the cause of death might be explained by an aggravation of an ongoing neuro-inflammation. | 20733304 |
| eosinophil, Inflammation, Nasal Polyps | Altered Intercellular Communication | Nasal polyps develop as a result of chronic inflammation, mostly accompanied by pronounced eosinophil leukocyte infiltration. | 20734966 |
| Inflammation, Prostate carcinoma, Structure of posterior cerebral artery | Altered Intercellular Communication | Recent studies identified an increased risk of prostate cancer (PCa) in Caucasian men harboring polymorphisms of genes involved in innate immunity and inflammation. | 20735825 |
| Inflammation, Calcinosis, Heart valve disease | Altered Intercellular Communication | It is possible that the lower plasma concentration of TGF-b1 in patients with valvular heart disease and the lack of its regulatory effect results in the increased inflammation and calcification seen in DHVs. | 20736227 |
| Pneumonia, Carcinogenesis, Infection, Carcinoma of lung, Pneumonitis | Altered Intercellular Communication | The increased lung cancer risk associated with recurrent pneumonia supports the hypothesis that chronic pulmonary inflammation arising from infections contributes to lung carcinogenesis. | 20736841 |
| Disturbance, Inflammation, Eye Abnormalities, Pain Distress Question | Altered Intercellular Communication | Outcome measures included return of normal vision, absence of motility disturbance, and resolution of pain, inflammation, eyelid abnormalities, and other symptoms. | 20736875 |
| Inflammation | Altered Intercellular Communication | COMP is the first extracellular matrix protein for which an active role in inflammation has been demonstrated in vivo. | 20737467 |
| Inflammation, Necrosis | Altered Intercellular Communication | A noninvasive procedure was devised to diagnose the termination of an inflammatory process in the necrotic process in MI, which implies the determination of salivary ceruloplasmin, if the latter is less than 106 mg/l, inflammation completeness in the necrotic area is diagnosed. | 20737674 |
| Refractory anemias, Rheumatoid Arthritis, Inflammation | Altered Intercellular Communication | The wrist is almost invariably affected in rheumatoid arthritis (RA) and inflammation of the wrist can lead to impaired function and eventually to severe destruction. | 20738208 |
| Inflammation, Arthritis of wrist, Swelling, Pain Distress Question | Altered Intercellular Communication | Classical signs of inflammation, pain, swelling and heat may often be observed in clinical examination of wrist arthritis and in ultrasound (US) investigation. | 20738208 |
| Refractory anemias, Inflammation | Altered Intercellular Communication | Correlation coefficients between clinical and ultrasound parameters of RA wrist inflammation in this study were fair to moderate. | 20738208 |
| Inflammation, Pain Distress Question, Erythema, Swelling, Renal Insufficiency, Arthritis | Altered Intercellular Communication | The classical signs of inflammation (pain, swelling, redness, heat and impaired function) seem to reflect different aspects of arthritis. | 20738208 |
| Refractory anemias, Inflammation, destruction joint, Rheumatoid Factor | Altered Intercellular Communication | Monocytes/macrophages accumulate in the rheumatoid (RA) synovium where they play a central role in inflammation and joint destruction. | 20738854 |
| Gastritis | Altered Intercellular Communication | The results suggest an angiotensin II mediated impact on mucosal epithelial functions, antral endocrine properties, microvascular permeability, and gastric inflammation. | 20739374 |
| Inflammation, Diabetes Mellitus, Non-Insulin-Dependent | Altered Intercellular Communication | The oxidative stress becomes evident as a result of accumulation of ROS in conditions of inflammation and Type 2 diabetes mellitus (T2DM). | 20739761 |
| Inflammation, Demyelination, Polyradiculoneuropathy, Chronic Inflammatory Demyelinating | Altered Intercellular Communication | In resource-restricted settings where these techniques are not freely available, it is useful to determine the utility of 'supportive' pathologic criteria (subperineurial edema, inflammation, onion bulb formation, and demyelination) proposed by AAN for diagnosis of CIDP. | 20739789 |
| Inflammation, Demyelination | Altered Intercellular Communication | Frequency of specific pathological alterations such as demyelination, inflammation, onion bulb formation, and axonal changes in sural nerve biopsies was evaluated. | 20739789 |
| Inflammation | Altered Intercellular Communication | Endoneurial inflammation was frequent in the relapsing-remitting form and epineurial inflammation and axonal changes in those with progressive course. | 20739789 |
| Inflammation, Pneumonia | Altered Intercellular Communication | Osteopontin is likely to contribute to the development of inflammation in patients with eosinophilic pneumonia. | 20796249 |
| Inflammation, Obesity | Altered Intercellular Communication | Inflammation and obesity are associated with AF, but the relationship between AF and pericardial fat is unknown. | 20797492 |
| Inflammation, Atherosclerosis, Cardiovascular Diseases, Diabetes Mellitus, Obesity | Altered Intercellular Communication | Excess secretion of various adipocyte-derived molecules has been linked with insulin resistance, obesity, diabetes, inflammation, atherosclerosis, and cardiovascular disease. | 20798476 |
| Inflammation | Altered Intercellular Communication | Markers of chronic inflammation with short-term changes in physical activity. | 20798662 |
| Inflammation, Behavior | Altered Intercellular Communication | Regular exercise is inversely related to markers of chronic inflammation, but we do not know to what extent these changes are the product of recent exercise behavior. | 20798662 |
| Inflammation, Hydronephrosis | Altered Intercellular Communication | In patients with acute inflammation or hydronephrosis individual treatment concepts are required. | 20799024 |
| Degenerative polyarthritis, Inflammation | Altered Intercellular Communication | We have recently reported that HMGB1 is released by osteoarthritic synoviocytes after activation with interleukin-1beta (IL-1b) The present study investigated the role of HMGB1 in synovial inflammation in osteoarthritis (OA). | 20799933 |
| Inflammation, Guillain-Barre Syndrome, Familial | Altered Intercellular Communication | We observed a major sensitivity to carbonylation for albumin and alpha-glycoprotein in inflammation and a selective increase of reactivity for a glycosylated Fab from an IgM globulin in GBS CSF. | 20801190 |
| ARCN1 gene, Chronic Obstructive Airway Disease, Airway structure | Altered Intercellular Communication | Chronic obstructive pulmonary disease (COPD) therapy is complicated by corticosteroid resistance of the interleukin 8 (IL-8)-dependent and granulocyte macrophage-colony stimulating factor (GM-CSF)-dependent chronic airway inflammation, for whose establishment human airway smooth muscle cells (HASMCs) might be crucial. | 20801891 |
| Inflammation, Papilledema | Altered Intercellular Communication | This condition is due to inflammation of the optic nerve sheath and is often mistaken for papilledema or papillitis. | 20802364 |
| Cellulite, Lymphangitis, Inflammation, Necrosis | Altered Intercellular Communication | Inflammation, dehiscence, cellulites, lymphangitis, drainage, necrosis, or abscess necessitating dressing, antibiotics or debridement before complete healing without eschar were defined as wound complications. | 20802911 |
| Colitis | Altered Intercellular Communication | Derivation of a T2-weighted MRI total colonic inflammation score (TCIS) for assessment of patients with severe acute inflammatory colitis-a preliminary study. | 20803202 |
| Trachoma , Perifolliculitis | Altered Intercellular Communication | The prevalence of trachomatous inflammation-follicular (TF) among children was 1.32% [95% CI, 0.77-1.86] in Gatsibo and 0.73% 195% CI, 0.33-1.13] in Nyaruguru Districts, respectively; with both districts having a prevalence below the WHO/International Trachoma Initiative (ITI) cut-off point of 10% for trachoma to be taken as disease of public health importance. | 20803920 |
| Osteomyelitis, Diabetes Mellitus | Altered Intercellular Communication | [Modulation of platelet tyrosine phosphatases by arachidonic acid metabolites in diabetes mellitus complicated with acute pyogenic inflammation]. | 20804071 |
| Inflammation, Heart failure | Altered Intercellular Communication | These data provide further evidence for an association between chronic inflammation and the development of heart failure. | 20804707 |
| Inflammation, Fibrosis Assessment | Altered Intercellular Communication | Osteopontin (OPN) is a glycoprotein that has been associated with inflammation and fibrosis. | 20805171 |
| Inflammation, Rheumatoid Arthritis, Osteopenia | Altered Intercellular Communication | Effect of intra-articular corticosteroid injections and inflammation on periarticular and generalised bone loss in early rheumatoid arthritis. | 20805297 |
| Refractory anemias, Inflammation | Altered Intercellular Communication | These data emphasise the importance of suppressing inflammation in patients with active RA to maintain bone health. | 20805297 |
| Inflammation, Cardiac complication, Diabetes Mellitus, GDC Disease Response Terminology | Altered Intercellular Communication | Persons with diabetes who had higher levels of CRP and BMI were less likely to have DR. Further research is needed to understand the interrelationship role of inflammation, body weight, and microvascular complications. | 20805569 |
| Inflammation, Malnutrition, Cardiovascular Diseases | Altered Intercellular Communication | In patients without cardiovascular disease, malnutrition and inflammation were associated with vascular prostheses, while pro-BNP was lower in obese patients. | 20805692 |
| Steatohepatitis, Inflammation, Fatty Liver Disease | Altered Intercellular Communication | These findings point toward the possible influence of age in the severity of steatohepatitis, portal and lobar inflammation in patients suffering from NASH while gender independently might contribute to the level of steatohepatitis. | 20806434 |
| Inflammation, Degenerative polyarthritis, Degenerative aortic valve disease, Age related macular degeneration, Autolysosome | Altered Intercellular Communication | To examine the relationship between degenerative aortic valve disease and osteoarthritis Background: Degenerative aortic valve disease (DAVD) and osteoarthritis (OA) are age-related degenerative diseases whose pathogenesis involves mechanical stress and local inflammation. | 20806543 |
| Inflammation, Secondary malignant neoplasm of liver | Altered Intercellular Communication | Liver metastases are present in many of these patients and some of them may display significant systemic inflammation. | 20806616 |
| Inflammation, Fibrosis Assessment, Tissue Adhesions | Altered Intercellular Communication | Inflammation and subsequent fibrosis, adhesions, or plicae may limit normal capsular compliance and decrease volume capacity of the knee. | 20807861 |
| Inflammation, Diabetes Mellitus | Altered Intercellular Communication | Magnesium intake in relation to systemic inflammation, insulin resistance, and the incidence of diabetes. | 20807870 |
| Inflammation, Diabetes Mellitus | Altered Intercellular Communication | To investigate the long-term associations of magnesium intake with incidence of diabetes, systemic inflammation, and insulin resistance among young American adults. | 20807870 |
| Pulmonary arterial hypertension, Inflammation, Vascular System Injuries | Altered Intercellular Communication | Limited systemic sclerosis patients with pulmonary arterial hypertension show biomarkers of inflammation and vascular injury. | 20808962 |
| Inflammation, Vascular System Injuries | Altered Intercellular Communication | The gene expression and cytokine profiles of lSSc-PAH patients suggest the presence of activated monocytes, and show markers of vascular injury and inflammation. | 20808962 |
| Inflammation, Hypertension, CTCAE | Altered Intercellular Communication | Association between cystatin C and inflammation in patients with essential hypertension. | 20809110 |
| Renal Insufficiency, Inflammation | Altered Intercellular Communication | It is known that the initiation and progression of these cardiovascular events contributes to renal dysfunction and chronic inflammation. | 20809110 |
| Inflammation, Diabetes Mellitus, Non-Insulin-Dependent, Atherosclerosis | Altered Intercellular Communication | Inflammation plays an important role in the pathophysiology of both atherosclerosis and type 2 diabetes and some inflammatory markers may also predict the risk of developing type 2 diabetes. | 20809989 |
| Inflammation, Functional Disability, Inflammatory polyarthritis | Altered Intercellular Communication | To assess the impact of the knee joint inflammation, detected by ultrasonography (US), on functional disability in patients with recent-onset inflammatory polyarthritis (IP). | 20810032 |
| Inflammation, Synovial Hypertrophy, Synovial Fluid | Altered Intercellular Communication | Joint group involvement was defined when at least one joint showed intra-articular signs of inflammation (synovial fluid abnormalities and/or synovial hypertrophy), according to the OMERACT definitions. | 20810032 |
| Inflammation | Altered Intercellular Communication | The mean difference of HAQ between patients with and without US knee inflammation was 0.42 (95%CI 0.22, 0.62; p<0.001). | 20810032 |
| Inflammation, Ulcer | Altered Intercellular Communication | After detailed history every patient underwent a comprehensive ophthalmic slit lamp bio-microscopical examination, for characteristics of the ulcer to locate the site, size, depth of ulcer and anterior chamber inflammation. | 20810053 |
| Inflammation, Nasal Polyps, Asthma | Altered Intercellular Communication | Nasal polyps from 70 Belgian patients, 34% with asthma, were analyzed for type of inflammation, T-cell cytokines, and IgE antibodies to Staphylococcus aureus enterotoxins. | 20810157 |
| Inflammation, Nasal Polyps | Altered Intercellular Communication | Mucosal inflammation in nasal polyps orchestrated by T(H)2 cytokines and amplified by S aureus enterotoxins is characterized by an increased eosinophilic inflammation and formation of IgE antibodies. | 20810157 |
| Inflammation, Bacterial sepsis | Altered Intercellular Communication | Elevated serum cytokines correlate with inflammation but are of limited use to differentiate between active AOSD and bacterial sepsis. | 20810496 |
| Airway structure, Inflammation | Altered Intercellular Communication | A total of 60 elderly subjects contributed up to 12 weekly measurements of fractional exhaled nitric oxide (NO; airway inflammation biomarker), and plasma interleukin-6 (IL-6; systemic inflammation biomarker). | 20811287 |
| Inflammation, Hematoma, Hemorrhage, Communicable Diseases, Postoperative Complications, Reactive Cutaneous Fibrous Lesion | Altered Intercellular Communication | We compared local tissue inflammation and fibrous reaction, postoperative complications (bleeding, wound haematoma, wound infection) and postoperative recovery time (time of mobilisation) in rats (Fischer strain) after implantation of a polypropylene mesh (PPM) (Prolene, Ethicon, Bracknell, UK) or a dual component fibrin mesh (DCFM) (Tachosil, Nycomed, Marlow, UK), between the muscle layer and the fascia transversalis defect. | 20811761 |
| Inflammation, Psychiatric | Altered Intercellular Communication | Interferon-gamma-inducible kynurenines/pteridines inflammation cascade: implications for aging and aging-associated psychiatric and medical disorders. | 20811799 |
| Inflammation, Impaired cognition, Metabolic Syndrome X, Depression, CTCAE, Mental disorders | Altered Intercellular Communication | This review of literature and our data suggests that up-regulated production of interferon-gamma (IFNG) in periphery and brain triggers a merger of tryptophan (TRY)-kynurenine (KYN) and guanine-tetrahydrobiopterin (BH4) metabolic pathways into inflammation cascade involved in aging and aging-associated medical and psychiatric disorders (AAMPD) (metabolic syndrome, depression, vascular cognitive impairment). | 20811799 |
| Arterial Stiffness, Inflammation | Altered Intercellular Communication | In long-term normoalbuminemic Japanese hemodialysis patients, with low prevalence of inflammation, OPG levels were strongly linked with both arterial stiffness and worse outcome. | 20812007 |
| Vasculitis, CTCAE, Interstitial inflammation, Non-necrotizing granulomatous inflammation | Altered Intercellular Communication | Histology of a surgical lung biopsy showed interstitial inflammation, vasculitis and non-caseating granulomas. | 20812157 |
| Rheumatoid Arthritis, Atlanto-Axial joint, Inflammation, Neck Pain | Altered Intercellular Communication | Rheumatoid arthritis involving the atlanto-axial region should be considered in patients with persisting neck pain and signs of inflammation. | 20812156 |
| Inflammation, Musculoskeletal Pain | Altered Intercellular Communication | Polymyalgia rheumatica (PMR) is characterized by aching of the proximal muscles and increased blood levels of markers of inflammation. | 20812339 |
| Inflammation, Muscle complaint | Altered Intercellular Communication | Despite the muscle complaints, the current view is that symptoms are caused by inflammation in synovial structures. | 20812339 |
| Inflammation, Fibrosis Assessment, Lymphoma, Pseudolymphoma | Altered Intercellular Communication | Histopathologic findings included: chronic inflammation in 450 patients (95.5%), fibrosis in 18 patients (3.8%), lymphoma in two patients (0.4%) and reactive lymphoid hyperplasia in one patient (0.2%). | 20812824 |
| Inflammation, Fibrosis Assessment | Altered Intercellular Communication | Chronic inflammation and fibrosis are the most common histopathologic findings in lacrimal sac specimens obtained during DCR. | 20812824 |
| Autoimmune Diseases, Keratitis, Herpetic, Inflammatory abnormality of the eye | Altered Intercellular Communication | Cryptic ocular herpes may confound matters in someone with an autoimmune disease thought to be the sole source of ocular inflammation. | 20812857 |
| Inflammation | Altered Intercellular Communication | Inflammation, oxidative stress, and high concentration of serum lipoprotein (a) [Lp (a)] are common complications in hemodialysis patients. | 20812958 |
| Fibrous, Inflammation, Calcinosis, Dental Plaque | Altered Intercellular Communication | With increasing age, plaque calcification and large lipid core increased (P<0.001 and P=0.01, respectively) and fibrous tissue (P=0.01) decreased, but lymphocyte infiltration of the plaque (P=0.03) and cap (P=0.002) and overall plaque inflammation (P=0.03) also decreased such that overall plaque instability was unrelated to age. | 20814007 |
| Barrett Esophagus, Esophageal mucous membrane, Inflammation, Chronic esophagitis | Altered Intercellular Communication | Mixed reflux of the gastroduodenal contents induces the esophageal mucosal damage and inflammation progressing chronic esophagitis and premalignant Barrett's esophagus (BE). | 20814068 |
| Inflammation, Adenocarcinoma Of Esophagus | Altered Intercellular Communication | The role of cyclooxygenase-2 (COX-2) and chronic inflammation in the progression of BE toward adenocarcinoma of the esophagus has not been extensively studied in experimental models of BE in animals and in human subjects. | 20814068 |
| Inflammation, Malnutrition, Comorbidity | Altered Intercellular Communication | Various factors may contribute to malnutrition in these patients including energy and protein intake, inflammation, and comorbidity. | 20814118 |
| Airway structure, Asthma | Altered Intercellular Communication | Clinical correlates and determinants of airway inflammation in pediatric asthma. | 20815308 |
| Airway structure, Asthma | Altered Intercellular Communication | Airway inflammation is a key component in the pathophysiology of asthma. | 20815308 |
| Inflammation, Asthma | Altered Intercellular Communication | However, neither its role in the clinical features of asthma nor the factors affecting the degree of inflammation have been fully defined. | 20815308 |
| Airway structure, Asthma | Altered Intercellular Communication | Airway inflammation, as determined by FE(NO), is only weakly associated with the clinical expression of asthma and spirometry results. | 20815308 |
| Allergic, Inflammation, IL13 gene, Allergy - Charge Type Reason | Altered Intercellular Communication | Asthma is similarly associated with allergic and nonallergic rhinitis, suggesting a link between upper and lower airways beyond allergy associated inflammation. | 20816191 |
| Degenerative polyarthritis, Inflammation, Nasal cartilage loss | Altered Intercellular Communication | The role of inflammation in osteoarthritis (OA) pathogenesis is unclear, and the associations between inflammatory cytokines and cartilage loss have not been reported. | 20816981 |
| Degenerative polyarthritis, Inflammation, Nasal cartilage loss | Altered Intercellular Communication | Serum levels of IL-6 and TNF-a are associated with knee cartilage loss in older people suggesting low level inflammation plays a role in the pathogenesis of knee OA. | 20816981 |
| Inflammation, Periodontal Diseases, Atherosclerosis | Altered Intercellular Communication | The candidates contributing to atherosclerosis in periodontal disease include low-grade inflammation such as C-reactive protein (CRP) and insulin resistance. | 20817211 |
| Inflammation | Altered Intercellular Communication | Accumulation of LPC (1-acyl 16:0), PC (1-acyl 36:4) and SM (d18:1/16:0) in the VV tissues suggested that inflammation associated with abnormal lipid metabolism may contribute to the development of VV. | 20817502 |
| Inflammation, Albuminuria, Chronic Kidney Diseases | Altered Intercellular Communication | Vitamin D deficiency, inflammation, and albuminuria in chronic kidney disease: complex interactions. | 20817560 |
| Proteinuria, Inflammation, Chronic Kidney Diseases, Cardiovascular Diseases | Altered Intercellular Communication | Although proteinuria is a marker of kidney and cardiovascular disease, few studies have examined vitamin D levels, inflammation, and proteinuria simultaneously in CKD. | 20817560 |
| Inflammation, Albuminuria | Altered Intercellular Communication | IL-6 may be an important intermediary between vitamin D deficiency and albuminuria, or vitamin D deficiency may contribute to inflammation and subsequent albuminuria. | 20817560 |
| Inflammation, Pulmonary Emphysema | Altered Intercellular Communication | Therefore, we hypothesize that the LTB4 pathway plays an important role in the pathogenesis of neutrophilic inflammation that contributes to pulmonary emphysema. | 20817777 |
| Pulmonary Emphysema, Pneumonitis | Altered Intercellular Communication | Together, these findings demonstrated that LTB4 played an important role in promoting the pathogenesis of pulmonary emphysema associated with neutrophilic pulmonary inflammation. | 20817777 |
| Pain Distress Question, Fasciitis, Inflammation | Altered Intercellular Communication | Plantar fasciitis is commonly treated with corticosteroid injections to decrease pain and inflammation. | 20817847 |
| Inflammation, Duodenal atrophy | Altered Intercellular Communication | Duodenal dystrophy is a rare disease, characterized by the chronic inflammation of the aberrant pancreatic tissue in the duodenal wall. | 20818113 |
| Dystrophy, Inflammation | Altered Intercellular Communication | A diagnosis of cystic dystrophy of the vertical part of the duodenum without chronic inflammation of the orthotopic pancreas was established in both cases by multi-detector computed tomography, magnetic resonance imaging and endosonography. | 20818113 |
| Calcinosis, Chronic inflammation | Altered Intercellular Communication | Biopsies of walls of the orbital cyst showed fragments of neuroglial and meningothelial tissues with some calcification and mild chronic inflammation. | 20818257 |
| Inflammation, Diabetes Mellitus | Altered Intercellular Communication | Our findings suggest that in NOD mice serum TGF-b1 levels during the natural history of the diabetes reflect the course of islet inflammation. | 20819089 |
| Dystrophy, Myositis, Polymyositis, Muscular Dystrophy, Dermatomyositis | Altered Intercellular Communication | The study included 20 cases of definite polymyositis, 20 cases of dermatomyositis and 10 cases of dystrophies with muscle inflammation (inflammatory muscular dystrophy). | 20819442 |
| Dystrophy, Polymyositis, Myositis | Altered Intercellular Communication | The results suggest that MHC-I detection alone cannot be used as a reliable diagnostic test to differentiate polymyositis from dystrophies with secondary muscle inflammation. | 20819442 |
| Inflammation, Depression, CTCAE, Coronary heart disease | Altered Intercellular Communication | Glucocorticoid signaling exerts major roles in inflammation, metabolism and depression, which are three crucial factors accompanying or underlying coronary heart disease. | 20819629 |
| Inflammation, Neoplasm Metastasis | Altered Intercellular Communication | One RFA-treated metastasis with rim-shaped uptake was regarded as inflammation. | 20819630 |
| Inflammation, Adenocarcinoma of lung (disorder) | Altered Intercellular Communication | Up-regulation of the expression of S100A8 and S100A9 in lung adenocarcinoma and its correlation with inflammation and other clinical features. | 20819668 |
| Adenocarcinoma, Inflammation | Altered Intercellular Communication | The higher expression was found to be correlated with the clinical characteristics of adenocarcinoma, inflammation and stage IV lesion. | 20819668 |
| Inflammation, Primary malignant neoplasm, Stage I Lung Cancer AJCC v8, Adenocarcinoma of lung (disorder) | Altered Intercellular Communication | S100A8, S100A9 up-regulation was found in the lung adenocarcinoma and end stage lung cancer tissue, the correlation of which with their higher expression in inflammatory lung tissues may indicate the collaborative effect of inflammation on the progression of cancer. | 20819668 |
| Inflammation, Non-alcoholic Fatty Liver Disease | Altered Intercellular Communication | Portal inflammation is associated with advanced histological changes in alcoholic and non-alcoholic fatty liver disease. | 20819880 |
| Inflammation, Non-alcoholic Fatty Liver Disease, Chronic liver disease, Fatty Liver Disease | Altered Intercellular Communication | Fatty liver disease (FLD), of either alcoholic (AFLD) or non-alcoholic (NAFLD) aetiologies, is characterised histologically by features that are lobulocentric that typically affect zone 3, in contrast with portal-based inflammation characteristics of other forms of chronic liver disease. | 20819880 |
| Inflammation, Non-alcoholic Fatty Liver Disease | Altered Intercellular Communication | The authors aimed to determine the prevalence and significance of portal inflammation in a cohort of adults diagnosed as having AFLD and NAFLD. | 20819880 |
| Inflammation, Non-alcoholic Fatty Liver Disease | Altered Intercellular Communication | More than a mild degree of portal inflammation was found in 47% of AFLD compared with 30% in NAFLD subgroup. | 20819880 |
| Inflammation, Non-alcoholic Fatty Liver Disease, Hypertension, CTCAE, Diabetes Mellitus | Altered Intercellular Communication | A higher degree of portal inflammation in AFLD was associated with a higher mean corpuscular volume, gamma glutamyl transferase (GGT) and alkaline phosphatase, and a lower platelet count and albumin, whereas in NAFLD this was associated with age, presence of diabetes, hypertension, body mass index (BMI), higher fasting blood glucose, cholesterol, alanine transaminase, GGT and ferritin. | 20819880 |
| Inflammation, Fibrosis Assessment, Non-alcoholic Fatty Liver Disease, Fatty degeneration | Altered Intercellular Communication | On regression analysis, portal inflammation was associated with the severity of steatosis (p=0.005), presence of ballooning (p=0.030) in NAFLD and severity of fibrosis in both AFLD and NAFLD (p<0.001). | 20819880 |
| Inflammation, Non-alcoholic Fatty Liver Disease | Altered Intercellular Communication | Portal inflammation is a common component of histological spectrum of both AFLD and NAFLD. | 20819880 |
| Inflammation | Altered Intercellular Communication | In both conditions portal inflammation is associated with clinical and histological features suggestive of advanced disease. | 20819880 |
| Primary malignant neoplasm, Liver carcinoma, FAM126A gene | Altered Intercellular Communication | Hepatocellular carcinoma (HCC) is a type of inflammation-related cancer that usually follows chronic inflammations. | 20820981 |
| Inflammation, Neoplasms | Altered Intercellular Communication | The levels of LTD4 were neither associated with parameters expressing tumor burden, such as AFP, nor with inflammation factors AST and g-GT. | 20820981 |
| Primary malignant neoplasm, Liver carcinoma, FAM126A gene | Altered Intercellular Communication | Hepatocellular carcinoma (HCC) is a type of inflammation-related cancer that usually follows chronic inflammations. | 20820981 |
| Nutritional Deficiency, Inflammation, Anemia, Chronic Kidney Diseases | Altered Intercellular Communication | About one third of persons have anemia secondary to a nutritional deficiency, one third have anemia caused by chronic inflammation or chronic kidney disease, and one third have unexplained anemia. | 20822082 |
| Inflammation, Anemia, Chronic Kidney Diseases | Altered Intercellular Communication | Anemia of chronic inflammation or chronic kidney disease may respond to treatment of the underlying disease and selective use of erythropoiesis-stimulating agents. | 20822082 |
| Extrinsic allergic alveolitis, Inflammation, Ground Glass Opacity, Alveolitis | Altered Intercellular Communication | The CT scan appearance, showing mosaic ground-glass opacities in the ventilated parts of the lung, the centrolobular predominance of inflammation on the lung sections, and the presence of a lymphocytic alveolitis at BAL suggested a hypersensitivity pneumonitis. | 20822994 |
| Ischemia, Meningitis | Altered Intercellular Communication | These neuroimages of our patient supported that leptomeningeal inflammation and the adjacent cerebrocortical ischemia could cause encephalitis-like symptoms in RLM patients. | 20823656 |
| Inflammation, Villous atrophy | Altered Intercellular Communication | In 2006-2008, we collected duodenal/jejunal biopsy data on CD (Marsh 3: villous atrophy, VA; n=29,008 unique individuals) and inflammation (Marsh 1-2; n=13,200) from all 28 pathology departments in Sweden. | 20823839 |
| Inflammation, HIV Infections | Altered Intercellular Communication | However, markers of inflammation and platelet activation were not appreciably changed suggesting that the biologic properties of these agents differ in persons with HIV infection. | 20824151 |
| Inflammatory Bowel Diseases, Inflammation, Mesenteric Venous Thrombosis | Altered Intercellular Communication | Mesenteric thrombosis is a rare complication of IBD and may develop during clinical remission, suggesting a potential role for factors other than clinically significant inflammation in its pathogenesis. | 20824370 |
| Inflammation, diabetic | Altered Intercellular Communication | [A non-abscess-forming inflammation of the corpora cavernosa in a diabetic patient - case report]. | 20824577 |
| Inflammation, Thrombosis, Neoplasms, Specimen Source Codes - Abscess, Corpus cavernosum structure, Embolism | Altered Intercellular Communication | An inflammation of the corpus cavernosum is relatively rare and must be differentiated from a tumour, abscess, thrombosis or embolism of the penile vessels. | 20824577 |
| Occluded, Corpus cavernosum structure, Inflammation, Infection | Altered Intercellular Communication | Most frequently inflammation of the corpus cavernosum is caused by iatrogenic interventions, followed by general infections and acute occlusion of penile vessels. | 20824577 |
| Inflammation, diabetic, Specimen Source Codes - Abscess | Altered Intercellular Communication | In the case of a 51-year-old diabetic patient with painful induration of the penis, an MR imaging study was undertaken to identify an inflammation of the corpora by exclusion of abscess formation. | 20824577 |
| Inflammation | Altered Intercellular Communication | The inflammation responded well to a two-week oral Fluorchinolon treatment. | 20824577 |
| Inflammation | Altered Intercellular Communication | Due to its high soft-tissue contrast, multiplanar layer images and, the MR scan was performed to identify an inflammation of the corpora cavernosa and to exclude an abscess formation. | 20824577 |
| Inflammation, Fracture, Osteoporosis, Crohn Disease | Altered Intercellular Communication | There is evidence to suggest that the inflammation associated with Crohn's disease (CD) impacts the bone health of patients, predisposing them to early onset osteoporosis and increasing their risk of fracture. | 20824813 |
| Inflammation | Altered Intercellular Communication | A liver biopsy showed well-preserved structures with minor signs of inflammation. | 20824971 |
| Orbital Pseudotumor, Pigment Epithelium | Altered Intercellular Communication | To present a rare idiopathic inflammation of the posterior segment of the eye - acute posterior multifocal placoid pigment epitheliopathy (APMPPE). | 20825067 |
| Inflammation, Asthma, Obesity | Altered Intercellular Communication | Obesity and asthma are characterized by the presence of inflammation. | 20825465 |
| Inflammation, Asthma, Obesity | Altered Intercellular Communication | We aimed to determine whether obesity influences asthmatic inflammation as well as the contribution of leptin or/and adiponectin to a possible linkage between asthmatic and obesity-related inflammation. | 20825465 |
| Airway structure, Inflammation, Bronchial Hyperreactivity, Obesity | Altered Intercellular Communication | Possible associations between variables expressing airway inflammation, bronchial hyper-responsiveness, systemic inflammation and obesity, as assessed by BMI, were evaluated. | 20825465 |
| Asthma | Altered Intercellular Communication | Alterations of leptin/adiponectin balance may be related to the presence of leukotriene inflammation in obese asthmatic patients. | 20825465 |
| Pain Distress Question, bone and joint infections, Myositis | Altered Intercellular Communication | A perirectal abscess as a cause of acute hip pain and inability to ambulate, with gluteus muscle inflammation but no evidence for bone or joint infection, has not been described, to the authors' knowledge. | 20825909 |
| Ischiorectal abscess, Abnormality, Inflammation | Altered Intercellular Communication | Computerized tomography (CT) of the hip and pelvis was then obtained, which was negative for boney abnormality but revealed a 5-cm ischiorectal abscess with inflammation of the adjacent gluteus muscle. | 20825909 |
| Inflammation, Impaired | Altered Intercellular Communication | In addition, we showed that telmisartan can reduce EPI-induced radical species, antagonize the inflammation, and reverse the early myocardial impairment. | 20826257 |
| Inflammation, Hyperviscosity, Myocardial dysfunction, Fibrinogen in blood above reference range | Altered Intercellular Communication | These findings support roles of inflammation, procoagulation, and hyperviscosity underlying hyperfibrinogenemia in the pathogenesis of incipient myocardial dysfunction. | 20826256 |
| Communicable Diseases, Disorder characterized by fever, Meningitis | Altered Intercellular Communication | All were admitted to hospital for febrile syndrome with abrupt clinical deterioration and suspected systemic infection without clear laboratory signs of meningeal inflammation. | 20827778 |
| Inflammation, Rheumatoid Arthritis | Altered Intercellular Communication | Alcohol consumption and markers of inflammation in women with preclinical rheumatoid arthritis. | 20827783 |
| Refractory anemias, Inflammation, Rheumatoid Arthritis | Altered Intercellular Communication | To examine the association between alcohol consumption and markers of inflammation in preclinical rheumatoid arthritis (RA). | 20827783 |
| Refractory anemias, Inflammation | Altered Intercellular Communication | These results demonstrate an association between alcohol consumption and markers of inflammation, including IL-6 and sTNFRII, in RA patients, prior to the occurrence of symptoms. | 20827783 |
| Acute Lung Injury, Inflammation | Altered Intercellular Communication | Endothelial microparticles induce inflammation in acute lung injury. | 20828748 |
| Diastolic dysfunction, Inflammation | Altered Intercellular Communication | Prolonged atrial electromechanical delay is due to provoked low-grade inflammation as well as LA enlargement and early LV diastolic dysfunction in obese subjects. | 20829801 |
| Asthma, Aspirin-Induced, Pneumonitis, Anguilla island | Altered Intercellular Communication | Aspirin-intolerant asthma (AIA), as a clinical syndrome caused by aspirin, is characterized by lung inflammation and reversible bronchoconstriction. | 20831471 |
| Aggressive behavior, Stomach Carcinoma | Altered Intercellular Communication | The significance of the Glasgow prognostic score (GPS), an inflammation-based prognostic score, as an indicator of aggressiveness in gastric carcinoma has not been investigated fully. | 20832047 |
| Stomach Carcinoma | Altered Intercellular Communication | The preoperative measurement of an inflammation-based prognostic score can demonstrate a strict stratification for the prognosis of patients with gastric carcinoma. | 20832047 |
| APP gene, Vascular Diseases, Inflammation, Aortic Aneurysm, Abdominal | Altered Intercellular Communication | Abdominal aortic aneurysm (AAA) is a complex vascular disease characterized by matrix degradation and inflammation and is a major cause of mortality in older men. | 20833395 |
| Inflammation, Fibrosis Assessment, Cardiac Arrhythmia, Atrial Fibrillation by ECG Finding | Altered Intercellular Communication | Inflammation, oxidative injury, altered myocyte metabolism, extracellular matrix remodeling and fibrosis initiate and perpetuate cardiac arrhythmias, especially atrial fibrillation. | 20833483 |
| deficiency aspects, Inflammation, Fibrosis Assessment, Myocardial, Cardiac Arrhythmia | Altered Intercellular Communication | Hence, it is likely that leukocyte and/or myocardial deficiency of EPA and DHA and consequent reduced formation of lipoxins, resolvins, protectins and maresins enhance inflammation and MPO activity that leads to myocardial damage and fibrosis and initiation and progression of cardiac arrhythmias. | 20833483 |
| Inflammation, Atrial Fibrillation by ECG Finding | Altered Intercellular Communication | Inflammation plays a role in the genesis and perpetuation of atrial fibrillation (AF). | 20833691 |
| Lepromatous, Peptic Ulcer, Gastrointestinal inflammation | Altered Intercellular Communication | These immunological results are consistent with previous histopathological studies illustrating a more severe gastrointestinal inflammation in lepromatous patients; importantly, a response to the 35 kDa antigen is recognized as a marker for the development of ulcerative disease. | 20835617 |
| Inflammation, Fibrosis Assessment, Aortic Aneurysm, Abdominal, Sigmoid colon, Inferior vena cava structure | Altered Intercellular Communication | Conventional open repair of inflammatory abdominal aortic aneurysms (IAAA) remains challenging through the presence of extensive peri-aortic inflammation and fibrosis which makes dissection and vascular control difficult with a risk of inadvertent injury to adjacent visceral structures such as the ureters, duodenum, inferior vena cava, left renal vein and sigmoid colon. | 20835894 |
| Inflammation, Fibrosis Assessment, Aortic Aneurysm, Abdominal | Altered Intercellular Communication | IAAAs and the associated peri-aortic inflammation and fibrosis can be successfully treated using endovascular abdominal aortic aneurysm repair with concurrent ureteric stenting. | 20835894 |
| Inflammation | Altered Intercellular Communication | These results suggest that regular exercise is an important nonpharmacological strategy to the improvement in inflammation in CAD patients. | 20835904 |
| Inflammation | Altered Intercellular Communication | Additionally, 27-OHC caused glutathione depletion, ROS generation, inflammation and apoptotic-mediated cell death. | 20836858 |
| Inflammation, Diabetic Foot | Altered Intercellular Communication | It is very suggestive that diabetic foot is characterized by a pronounced inflammatory reaction and the pathogenic significance of this inflammation has received little attention. | 20836881 |
| Inflammation, Chronic disease, Obesity | Altered Intercellular Communication | Increased childhood obesity and low-grade inflammation may contribute to later life chronic disease risk. | 20837281 |
| Inflammation, Parotid Diseases, Malignant Neoplasms | Altered Intercellular Communication | Various parotid gland diseases are seen clinically, including inflammation, sialolithiasis, and benign and malignant tumors. | 20837345 |
| Inflammatory Bowel Diseases, Gastrointestinal inflammation | Altered Intercellular Communication | Intestinal inflammation continued and impaired his quality of life; he was diagnosed with IBD of an undetermined type (IBD-U). | 20837584 |
| Inflammation, Inflammatory disorder | Altered Intercellular Communication | Because the use of anti-inflammatory drugs in general is a marker for underlying inflammatory disorders, inflammation may be the common cause for the use of anti-inflammatory drugs and chronic AF. | 20837831 |
| Palmar-plantar erythrodysesthesia syndrome, Leukopenia, Abdominal Pain, Inflammatory disease of mucous membrane, Fatigue | Altered Intercellular Communication | Grade 3 adverse events included abdominal pain, mucosal inflammation, fatigue, neutropenia, and hand-foot syndrome. | 20837944 |
| Shock, Traumatic | Altered Intercellular Communication | These findings suggest that hormonal differences play a role in the gender-based outcome disparities after traumatic shock. | 20838123 |
| Diffuse Axonal Injury, Inflammation | Altered Intercellular Communication | The extent of paranodal axoglial (neurofascin-155(+)/Caspr1(+)) disruption correlated with local microglial inflammation and axonal injury (expression of nonphosphorylated neurofilaments) in MS NAWM. | 20838243 |
| Inflammation, Experimental Autoimmune Encephalomyelitis | Altered Intercellular Communication | Disruption of the axoglial unit in adjuvant-immunized animals was reversible and coincided with the resolution of microglial inflammation; paranodal damage and microglial inflammation persisted in chronic EAE. | 20838243 |
| Diffuse Axonal Injury, Inflammation | Altered Intercellular Communication | These data indicate that, in MS NAWM, permanent disruption to axoglial domains in an environment of microglial inflammation is an early indicator of axonal injury that likely affects nerve conduction and may contribute to physiologic dysfunction. | 20838243 |
| Celiac Disease, Inflammatory disease of mucous membrane, Immune-mediated, Villous atrophy | Altered Intercellular Communication | Celiac disease is an immune-mediated enteropathy characterized by mucosal inflammation and villous atrophy of the small bowel upon exposure to ingested gluten. | 20839163 |
| vascular inflammations | Altered Intercellular Communication | In addition, oxidized LDL and high-sensitivity C-reactive protein were determined as markers of oxidative stress and vascular inflammation. | 20840194 |
| Inflammation, Benign prostatic hypertrophy | Altered Intercellular Communication | Transforming growth factor b-receptor II protein expression in benign prostatic hyperplasia is associated with prostate volume and inflammation. | 20840324 |
| Inflammatory Bowel Diseases, Inflammation | Altered Intercellular Communication | Inflammatory bowel disease (IBD) is associated with imbalances of the local intestinal immune responses, with dysregulated CD4(+) T cells contributing to the chronic inflammation. | 20840654 |
| Inflammation, Atherosclerosis | Altered Intercellular Communication | Inflammation contributes to atherosclerosis progression and influences both arginase and nitric oxide synthase expression. | 20842428 |
| TNF protein, human, Inflammation, Tumor necrosis | Altered Intercellular Communication | The markers of inflammation interleukin-6 (IL-6) and tumor necrosis factor-alpha (TNF-a) were also assessed. | 20842428 |
| HD Term Type | Altered Intercellular Communication | HD could be considered as an inflammatory condition. | 20842428 |
| Inflammation, Carcinogenesis, Malignant neoplasm of endometrium, Obesity | Altered Intercellular Communication | We provided epidemiological evidence that chronic inflammation might mediate the association between obesity and endometrial cancer and that endometrial carcinogenesis could be promoted by an inflammatory milieu. | 20843938 |
| Inflammation, Aortic Aneurysm, Abdominal, Diabetes Mellitus | Altered Intercellular Communication | The influence of diabetes on degree of abdominal aortic aneurysm tissue inflammation. | 20843966 |
| Nephritis | Altered Intercellular Communication | Expression of the chemokine receptor CCR6 in human renal inflammation. | 20844183 |
| Nephritis | Altered Intercellular Communication | tertiary lymphoid organs, develop in the tubulointerstitium during chronic renal inflammation. | 20844183 |
| Nephritis | Altered Intercellular Communication | CCR6 and the corresponding ligand CCL20 might therefore be involved in the recruitment of T and B cells to organized nodular infiltrates in chronic renal inflammation. | 20844183 |
| Rupture, Inflammation | Altered Intercellular Communication | Rupture of HO-1(-/-) macrophages in vivo and release of nonmetabolized heme probably caused tissue inflammation. | 20844238 |
| Inflammation, High-Frequency Microsatellite Instability | Altered Intercellular Communication | Unlike microsatellite instability-high (MSI-H) in which hypermethylation of hMLH1 occurs followed by multiple susceptible gene mutations, EMAST may be associated with inflammation and subsequent relaxation of MMR function with the biological consequences not known. | 20844976 |
| Myocardial immune cell infiltration, Inflammation | Altered Intercellular Communication | The etiology and consequences of EMAST are under investigation, but its association with immune cell infiltration suggests that inflammation may play a role for its development. | 20844976 |
| Communicable Diseases, Stenosis, Epididymo-orchitis, Urethritis, Sepsis due to urinary tract infection | Altered Intercellular Communication | The leading etiology of the stricture was urethral inflammation (76.4%) with the commonest complication being infection: wound infection in 9.1%, urosepsis in 3.6%, and epididymo-orchitis in 1.8% of the subjects. | 20845294 |
| Granulomatous inflammation, Caseous necrosis | Altered Intercellular Communication | A transbronchial lung biopsy was performed and the histopathologic examination of the specimen from this lesion revealed granulomatous inflammation without caseous necrosis or acid-fast bacilli. | 20845686 |
| Pulmonary Infiltrate, Inflammation, Tuberculosis, Pulmonary | Altered Intercellular Communication | We believe that these lesions were pulmonary tuberculomas and transient intra-pulmonary infiltration due to non-specific inflammation, caused secondarily by an excessive immune response, as in paradoxical worsening. | 20845686 |
| Inflammation, Disease remission, Atherosclerosis, Calcified (qualifier), Calcinosis | Altered Intercellular Communication | Calcific AS, as an active disease process, is characterized by lipid accumulation, inflammation and calcification that mimic atherosclerosis. | 20845892 |
| Inflammation | Altered Intercellular Communication | A total of 23 selected patients with post-surgical neuropathies received nerve biopsies, of which 21 demonstrated increased inflammation. | 20846945 |
| Pain Distress Question, Inflammation, Ischemia, Neuropathy, Neurologic Symptoms, Weakness, Inflammatory neuropathy | Altered Intercellular Communication | (i) not all post-surgical neuropathies are mechanical, and inflammatory mechanisms can be causative, presenting as pain and weakness in a focal, multifocal or diffuse pattern; (ii) these inflammatory neuropathies may be recognized by their spatio-temporal separation from the site and time of surgery and by the characteristic magnetic resonance imaging features; (iii) occasionally post-surgical inflammatory and mechanical neuropathies are difficult to distinguish and nerve biopsy may be required to demonstrate an inflammatory mechanism, which in our cohort often, but not exclusively, exhibited pathological features of microvasculitis and ischaemia; and (iv) recognizing the role of inflammation in these patients' neuropathy led to rational immunotherapy, which may have resulted in the subsequent improvement of neurological symptoms and impairments. | 20846945 |
| Inflammation, Data types - Address | Altered Intercellular Communication | Specifically, we analyzed reduced inflammation and improved metabolic profile as a potential medium through which the MeDi reduced the risk of AD. | 20847399 |
| Chronic disease | Altered Intercellular Communication | The causes of growth disorder include hormonal irregularities, chronic disease, complications during pregnancy or genetic conditions. | 20847595 |
| Inflammation, Hepatobiliary Neoplasm, Biliary Tract Hemorrhage, Cholelithiasis, Traumatic injury, Vascular anomaly | Altered Intercellular Communication | The causes of hemobilia include trauma, gallstone disease, vascular malformation, inflammation, and biliary or hepatic tumors. | 20847612 |
| Keratitis | Altered Intercellular Communication | Role of human herpes virus 6 in corneal inflammation alone or with human herpesviruses. | 20847652 |
| Keratitis | Altered Intercellular Communication | : In 22 patients with corneal inflammation, HHV-6 was positive in 14 of 22 patients and HSV-1 was found in 9 of those patients. | 20847652 |
| Keratitis | Altered Intercellular Communication | These data indicated that the association of HHV-6 with disease was more frequent than with other herpesviruses and that HHV-6 may be another sole causative agent for corneal inflammation. | 20847652 |
| Inflammation, Disorders of Porphyrin Metabolism | Altered Intercellular Communication | This case highlights the usefulness of tissue biopsy in porphyria when one is uncertain as to whether a necrotizing process is driven by inflammation or phototoxic damage. | 20847674 |
| Inflammation, Metabolic Syndrome X | Altered Intercellular Communication | Metabolic syndrome is marked by perturbed glucocorticoid (GC) signaling, systemic inflammation, and altered immune status. | 20847733 |
| Gastrointestinal inflammation | Altered Intercellular Communication | Glycogen synthase kinase 3-b: a master regulator of toll-like receptor-mediated chronic intestinal inflammation. | 20848477 |
| Gastrointestinal inflammation | Altered Intercellular Communication | Intestinal inflammation was evaluated by histologic analysis and cytokine secretion of mesenteric lymph node cells (MLC). | 20848477 |
| Inflammatory Bowel Diseases | Altered Intercellular Communication | The expression differences between ileal CD, colonic CD, and previously identified UC-associated miRNAs support the likelihood that miRNAs influence differing inflammation-related gene expression in each inflammatory bowel disease (IBD) subtype and may form the basis for future diagnostic tests and therapeutic targets for IBD. | 20848482 |
| Inflammation, Liver diseases | Altered Intercellular Communication | IL-17 as a new cytokine probably play a multiple role as immune factor and inflammation element in the progression of the chronic hepatitis B disease. | 20848848 |
| Sleep abnormalities, Parkinsonian Disorders | Altered Intercellular Communication | Dopamine is an important neurotransmitter in the regulation of the sleep-wake cycle, and parkinsonian patients suffer from prominent sleep abnormalities. | 20849470 |
| Communicable Diseases, Helicobacter pylori, Gastritis, Obesity | Altered Intercellular Communication | Infection with Helicobacter pylori, which induces persistent and uncontrolled gastric inflammation leading to decreased appetite, might be protective against obesity. | 20850344 |
| Uremia, Communicable Diseases, Inflammation, Anorexia | Altered Intercellular Communication | Hypothesis of the present study was that infection with H pylori in subjects with uremia might cause inflammation, diminished appetite, anorexia, and decreased IDWG. | 20850344 |
| Malnutrition | Altered Intercellular Communication | Malnutrition inflammation score, spKt/V, and normalized protein equivalent of total nitrogen appearance were determined. | 20850344 |
| Inflammation | Altered Intercellular Communication | Isolated granulomatous inflammation of the appendix is extremely rare, and its etiology is still unknown. | 20850613 |
| Inflammation, Pyelonephritis | Altered Intercellular Communication | Voiding cystourethrogram was investigated after acute pyelonephritis was confirmed by renal scan and acute inflammation subsided, about 2 to 4 weeks later. | 20850815 |
| Granulomatous inflammation | Altered Intercellular Communication | Two patients' lesions were biopsied, revealing granulomatous inflammation. | 20851656 |
| Intraocular inflammation | Altered Intercellular Communication | Although intraocular inflammation seemed to be successfully controlled, the number of giant-cell deposits on the posterior surface of the posterior capsule was gradually increased with the development of posterior capsular opacification in 5 and 9 months, respectively, and neodymium-doped yttrium-aluminum-garnet (Nd:YAG) laser capsulotomy was required. | 20854015 |
| Inflammation, Atherosclerosis | Altered Intercellular Communication | The measurements included markers of systemic inflammation, subclinical atherosclerosis, left ventricular mass index, composite and individual cardiovascular end points, and all-cause mortality. | 20854960 |
| Inflammation, Atherosclerosis | Altered Intercellular Communication | The MS plus MA group showed a consistently stronger association with the markers of systemic inflammation, subclinical atherosclerosis, and most clinical end points compared to the other study groups. | 20854960 |
| Renal Insufficiency, Inflammation, Heart failure, Muscle Cells | Altered Intercellular Communication | Higher levels were associated with features of worse heart failure and biomarkers of neurohormonal activation, inflammation, myocyte injury, and renal dysfunction. | 20855664 |
| Inflammation, Fibrosis Assessment, Retractile Mesenteritis | Altered Intercellular Communication | Sclerosing mesenteritis is a rare disease of unknown etiology that is characterized by self-limited, nonspecific inflammation and fibrosis of the mesenteric adipose tissue. | 20855700 |
| Neonatal stroke, White matter | Altered Intercellular Communication | Melatonin promotes myelination by decreasing white matter inflammation after neonatal stroke. | 20856166 |
| Infarction, Inflammation, Cerebrovascular accident | Altered Intercellular Communication | These results suggest that melatonin is not able to reduce cortical infarct volume in a neonatal stroke model but strongly reduces inflammation and promotes subsequent myelination in the white matter. | 20856166 |
| Inflammation, Helicobacter pylori | Altered Intercellular Communication | Relationship of the intensity of Helicobacter pylori and severity of inflammation with beta-2 microglobulin levels in serum according to the updated Sydney System. | 20856179 |
| Inflammation | Altered Intercellular Communication | We investigate the usability of beta-2 microglobulin as a simple marker that may reflect the severity of inflammation and intensity of HP in gastric mucosa. | 20856179 |
| Stomatitis | Altered Intercellular Communication | No statistically significant result was found between serum beta-2 microglobulin levels and the intensity of HP and the severity of inflammation of gastric mucosa. | 20856179 |
| Inflammation | Altered Intercellular Communication | We suggest that the serum beta-2 microglobulin level cannot be used as a simple marker of HP intensity and severity of inflammation in gastric endoscopic biopsies. | 20856179 |
| ARCN1 gene, Inflammation, Chronic Obstructive Airway Disease | Altered Intercellular Communication | chronic obstructive pulmonary disease (COPD) is characterized by chronic inflammation and structural alterations (ie, tissue remodeling) throughout the conducting airways, parenchyma, and pulmonary vasculature. | 20856827 |
| Inflammation, Coronary heart disease | Altered Intercellular Communication | Heart rate variability and biomarkers of systemic inflammation in patients with stable coronary heart disease: findings from the Heart and Soul Study. | 20857123 |
| Inflammation, Choline Dehydrogenase, Mitochondrial | Altered Intercellular Communication | Reduced cardiac autonomic control is associated with increased systemic inflammation in patients with stable CHD. | 20857123 |
| Inflammation, Chronic pain | Altered Intercellular Communication | MMP-9 and -13 mRNA levels were significantly elevated in patients with chronic pain, presumably as a consequence of neovascularization and chronic inflammation. | 20857147 |
| Inflammation, Chronic Obstructive Airway Disease, Allergic | Altered Intercellular Communication | The differences of eosinophil- and neutrophil-related inflammation in elderly allergic and non-allergic chronic obstructive pulmonary disease. | 20858153 |
| ARCN1 gene, Chronic Obstructive Airway Disease, Airway structure | Altered Intercellular Communication | Chronic obstructive pulmonary disease (COPD) is a common disease in the elderly population and is characterized by airway inflammation. | 20858153 |
| allergic inflammation | Altered Intercellular Communication | Whether it is a progressive condition resulting from allergic inflammation or a distinct condition involving a pathogen-induced reaction remains unclear. | 20858153 |
| ARCN1 gene, allergic inflammation | Altered Intercellular Communication | To determine the role of allergic inflammation in the pathogenesis of elderly COPD. | 20858153 |
| Blindness, Orbital Pseudotumor | Altered Intercellular Communication | Idiopathic orbital inflammation leading to unilateral blindness over a 2-day presentation in a child. | 20859233 |
| Orbital Pseudotumor | Altered Intercellular Communication | Orbital imaging revealed enlarged extraocular muscles, and biopsy confirmed idiopathic orbital inflammation. | 20859233 |
| Fibrosis Assessment, Pneumonitis | Altered Intercellular Communication | The hallmark of cystic fibrosis (CF) is chronic lung inflammation. | 20859300 |
| Inflammation, Cyclophosphamide/Vincristine/Dacarbazine Regimen, Cardiovascular Diseases | Altered Intercellular Communication | Lifestyle habits, vascular function and inflammation are components in the development of cardiovascular disease (CVD). | 20859301 |
| Inflammation | Altered Intercellular Communication | In contrast, chronic GvHD patients who did not develop acute GvHD earlier displayed significantly increased Treg cell numbers at the timepoint of chronic inflammation. | 20859740 |
| Fasciitis, Heel, Bursitis, Bone structure of calcaneum, Compression injury of nerve | Altered Intercellular Communication | According to the classification:67 heels with plantar fasciitis type, 61 heels with calcaneal bursitis type, 36 heels with plantar fat pad inflammation-based type, 6 heels with calcaneus high pressure-type, 21 heels with nerve compression type, 75 heels with mixed type. | 20860141 |
| Inflammation | Altered Intercellular Communication | Inflammation and immune response in acute aortic dissection. | 20860543 |
| Inflammation, Periodontitis, Coronary heart disease, Chronic disease, Choline Dehydrogenase, Mitochondrial | Altered Intercellular Communication | Coronary heart disease (CHD) and chronic periodontitis (CP) both are multifactorial chronic diseases and related to inflammation. | 20860764 |
| Inflammation, Dental Plaque, Dental caries | Altered Intercellular Communication | Children with severe caries (n = 39) had more dental plaque and gingival inflammation than caries-free children (n = 41). | 20861633 |
| Weight decreased, Nephritis | Altered Intercellular Communication | Surgically induced weight loss contributed to a decrease in blood pressure and markers of renal inflammation. | 20862711 |
| Inflammation, Blood coagulation | Altered Intercellular Communication | l-Carnitine supplement reduces serum CRP, a marker of systemic inflammation, and plasma fibrinogen, an inflammation-related coagulation factor, in hemodialysis patients. | 20863217 |
| Inflammation | Altered Intercellular Communication | We speculate that this lesion is due to inflammation of the biceps tendon resulting in increased biceps-humeral head contact pressure. | 20863719 |
| Acute Coronary Syndrome, Cardiovascular system | Altered Intercellular Communication | (FRANCIS [Fewer Recurrent Acute Coronary Events With Near-Term Cardiovascular Inflammation Suppression]-ACS Trial: A Study of the Safety and Efficacy of A 002 in Subjects With Acute Coronary Syndromes; NCT00743925). | 20863951 |
| Inflammation | Altered Intercellular Communication | IL-17A plays a role in small airway subepithelial inflammation, whereas IL-17F appears to play a more prominent role within lymphoid follicles. | 20864612 |
| Airway structure | Altered Intercellular Communication | The measurement of the exhaled nitric oxide fraction (FE(NO)) is proposed as a useful marker of airway inflammation. | 20864792 |
| Steatohepatitis, Non-alcoholic Fatty Liver Disease, Hypopituitarism, hormone deficiency | Altered Intercellular Communication | Severe growth hormone deficiency in hypopituitarism was associated with the severe degree of hepatic steatosis in NAFLD. | 20865648 |
| Communicable Diseases, Inflammation, Helminths | Altered Intercellular Communication | Infection with helminths is associated with shifts in host immunity, including increased production of immunoglobulin E (IgE) and reduced inflammation. | 20865759 |
| Inflammation, Fat necrosis, Pancreatitis Necrotizing | Altered Intercellular Communication | An incisional biopsy revealed lobular inflammation of subcutaneous fat, focal fat necrosis with saponification/ghost cells and scattered foreign-body type giant cells consistent with pancreatic fat necrosis/pancreatic panniculitis. | 20865849 |
| Inflammation, Erythema, Phrynoderma, Alopecia | Altered Intercellular Communication | Clinical effects, in the sense of stabilization with cessation of the inflammation (erythema, follicular hyperkeratosis, loss of anagen hair), were achieved in all patients but three. | 20868410 |
| Inflammation, Pulmonary Hypertension | Altered Intercellular Communication | Fractalkine (FKN), a unique chemokine associated with pulmonary hypertension, may be involved in the acute stress response that regulates inflammation after cardiopulmonary bypass (CPB) surgery. | 20869263 |
| Osteitis, Ear Inflammation | Altered Intercellular Communication | NOE may develop in patients with benign otitis media and externa, and must be considered in all patients with temporal bone inflammation, especially those with risk factors and those who fail to improve with more conservative measures. | 20869559 |
| RECIL MR | Altered Intercellular Communication | Aortic wall inflammation using USPIO-enhanced MR imaging is feasible. | 20869889 |
| Myopia, Ulcerative Colitis | Altered Intercellular Communication | The patient had not disclosed her history of a total colectomy for recurrent ulcerative colitis and developed bilateral stromal inflammation and corneal melting along the flap edge with ulceration within 3 days of uneventful bilateral LASIK for myopia. | 20870127 |
| Inflammation, Neoplasms | Altered Intercellular Communication | The most common findings were angiectasias (61.5%), inflammation (7.5%), and neoplasia (6.8%). | 20870226 |
| Autoimmune Diseases, Inflammation | Altered Intercellular Communication | Our results add weight to concerns that pollution may be an important trigger of inflammation and autoimmunity. | 20870568 |
| ARCN1 gene, Inflammation, Demographics Domain, Cardiovascular Diseases, Cyclophosphamide/Vincristine/Dacarbazine Regimen, Diabetes Mellitus, Cerebrovascular accident, Chronic Obstructive Airway Disease | Altered Intercellular Communication | Comorbidities associated with systemic inflammation including cardiovascular disease (CVD), stroke and diabetes mellitus (DM) are common among individuals with chronic obstructive pulmonary disease (COPD). | 20871122 |
| Inflammation | Altered Intercellular Communication | The adipocyte-derived cytokine leptin was implicated to link inflammation and metabolic alterations. | 20871818 |
| Inflammation, Critical Illness, Hyperglycemia | Altered Intercellular Communication | We investigated the potential role of leptin components in critically ill patients, because systemic inflammation, insulin resistance, and hyperglycemia are common features of critical illness. | 20871818 |
| Communicable Diseases, Inflammation, Fever, CTCAE | Altered Intercellular Communication | We conclude that fever, even up to the seventh postoperative day, is not substantially helpful to distinguish infection from general inflammation in clean orthopaedic surgery. | 20871993 |
| Acute Coronary Syndrome, Hemorrhage, Inflammation | Altered Intercellular Communication | Bleeding events are associated with an increase in markers of inflammation in acute coronary syndromes: an ACUITY trial substudy. | 20872045 |
| Inflammation, MS gene | Altered Intercellular Communication | Glial activation in the setting of central nervous system inflammation is a key feature of the multiple sclerosis (MS) pathology. | 20872081 |
| Inflammation | Altered Intercellular Communication | Focal increases in [(11)C]PBR28 binding corresponded to areas of active inflammation as evidenced by significantly greater binding in regions of gadolinium contrast enhancement compared to contralateral normal-appearing white matter (p = 0.0039). | 20872081 |
| Granuloma, Inflammation | Altered Intercellular Communication | Histological examination showed non-caseation granulomas in mesenteric lymph nodes and transmural inflammation in the cecum. | 20872335 |
| Inflammation, Malnutrition, Impaired cognition, Cardiovascular Diseases, Depression, CTCAE | Altered Intercellular Communication | In these patients, the early identification of the specific clinical problems that may cause many adverse effects for the dialysis treatment population becomes a relevant factor: e.g., cardiovascular diseases, malnutrition, inflammation, depression and cognitive disturbances. | 20872375 |
| Cessation of life, Inflammation, Coronary heart disease | Altered Intercellular Communication | Chronic inflammation and oxidative stress increase with advancing age and appear to be involved in the pathogenesis of coronary heart disease, the leading cause of death worldwide. | 20874680 |
| Inflammation, Intradermal Route of Drug Administration, Overweight | Altered Intercellular Communication | The lack of association between overweight and ID in the present study could be due to the fact that the excess of body fat of the women might not be critical to induce chronic inflammation related to reduced Fe absorption. | 20875192 |
| Alzheimers Disease", Data types - Address | Altered Intercellular Communication | Altered glutamatergic synaptic transmission is among the key events defining the course of Alzheimer's disease (AD). | 20875805 |
| glycation, Inflammation | Altered Intercellular Communication | Blockade of PKC-beta protects HUVEC from advanced glycation end products induced inflammation. | 20875828 |
| Inflammation, Endothelial dysfunction, Diabetes Mellitus, Non-Insulin-Dependent | Altered Intercellular Communication | The lack of utility of circulating biomarkers of inflammation and endothelial dysfunction for type 2 diabetes risk prediction among postmenopausal women: the Women's Health Initiative Observational Study. | 20876407 |
| Endothelial dysfunction, Inflammation, Demographics Domain, Diabetes Mellitus, Non-Insulin-Dependent | Altered Intercellular Communication | Recent studies have linked plasma markers of inflammation and endothelial dysfunction to type 2 diabetes mellitus (DM) development. | 20876407 |
| Inflammation, Malignant Neoplasms | Altered Intercellular Communication | However, serum Fe markers are influenced by inflammation or malignancy and may not accurately reflect the amount of body Fe. | 20876673 |
| Inflammation, Endotoxemia, Chronic Kidney Diseases, Cardiovascular Diseases | Altered Intercellular Communication | Circulating endotoxemia: a novel factor in systemic inflammation and cardiovascular disease in chronic kidney disease. | 20876680 |
| Inflammation, Malnutrition, Endotoxemia, Injury of cardiac valve | Altered Intercellular Communication | Resultant endotoxemia is associated with systemic inflammation, markers of malnutrition, cardiac injury, and reduced survival. | 20876680 |
| Acute Lung Injury, Pneumonitis, Respiratory Distress Syndrome, Newborn | Altered Intercellular Communication | Acute lung injury and acute respiratory distress syndrome (ALI/ARDS) are severe forms of bilateral lung inflammation with poor clinical outcomes. | 20877166 |
| glycation, Inflammation | Altered Intercellular Communication | Soluble receptor for advanced glycation endproducts (sRAGE) plays a key regulatory role during the acute phase of inflammation, and baseline plasma levels of sRAGE were recently found to be associated with severity of ALI/ARDS. | 20877166 |
| Inflammation, Ischemic stroke, Reperfusion Injury | Altered Intercellular Communication | Inflammatory cytokines are involved in the systemic inflammation, which precedes an ischaemic stroke (IS), and also participate into brain ischaemia-reperfusion injury. | 20880001 |
| Airway structure | Altered Intercellular Communication | Lung function was followed as FEV(1) and airway inflammation as fraction of exhaled nitric oxide (F(E) NO). | 20880055 |
| Inflammation, Aortic Aneurysm, Abdominal | Altered Intercellular Communication | A randomised placebo-controlled double-blind trial to evaluate lipid-lowering pharmacotherapy on proteolysis and inflammation in abdominal aortic aneurysms. | 20880729 |
| ARCN1 gene, Chronic Obstructive Airway Disease, exacerbation acute, Airway structure | Altered Intercellular Communication | Chronic obstructive pulmonary disease (COPD) is characterized by airway inflammation and is associated with acute exacerbations. | 20881376 |
| ARCN1 gene, Exacerbation, Airway structure | Altered Intercellular Communication | Erythromycin treatment in COPD patients can reduce airway inflammation and decrease exacerbations and may therefore be useful in the management of COPD. | 20881376 |
| Corneal edema, Hyperemia | Altered Intercellular Communication | On days 7, 14, 21 and 28, the frequency of inflammation-related signs (corneal edema, conjunctival hyperemia, anterior chamber or Tyndall reaction) as well as best-corrected visual acuity (BCVA) were measured. | 20881443 |
| Pseudoexfoliation | Altered Intercellular Communication | On day 21, pseudoexfoliation was associated with the presence of any inflammation-related sign (OR = 4.5; 95% CI: 1.2-16.0; p = 0.022). | 20881443 |
| Inflammation, Pathology | Altered Intercellular Communication | The pathologies promoting hospitalization could influence this derangement through inflammation but this hypothesis should be investigated. | 20882095 |
| Inflammation, Radiation Damage | Altered Intercellular Communication | Our hypothesis was that pretreatment inflammation in the lung makes pulmonary tissue more susceptible to radiation damage. | 20884128 |
| Inflammation | Altered Intercellular Communication | The relationship between pretreatment [(18)F]fluorodeoxyglucose ([(18)F]FDG) uptake in the lungs (as a surrogate for inflammation) and the delivered radiation dose and radiation-induced lung toxicity (RILT) was investigated. | 20884128 |
| Inflammation, Heart Arrest, Induced | Altered Intercellular Communication | On-pump coronary surgery with and without cardioplegic arrest: comparison of inflammation, myocardial, cerebral and renal injury and early and late health outcome in a single-centre randomised controlled trial. | 20884221 |
| Inflammation, Thrombosis, Ventricular Arrhythmia, CTCAE 5.0, Electrocardiogram: myocardial infarction (finding), ST Elevation Myocardial Infarction by ECG Finding, Shock, Dental Plaque | Altered Intercellular Communication | Statins favourably affect platelet adhesion, thrombosis, endothelial function, inflammation, plaque stability, and ventricular arrhythmia, which may potentially improve outcome after percutaneous coronary intervention (PCI) for ST-elevation myocardial infarction (STEMI) and shock. | 20884413 |
| Inflammation | Altered Intercellular Communication | PIs induced senescence markers, prelamin A accumulation, oxidative stress, and inflammation in HCAECs. | 20884875 |
| Granulomatous inflammation | Altered Intercellular Communication | Although hair cortex comedo was thought originally to be a variant of dilated pore of Winer, we believe that these distinctive lesions, which are characterized histopathologically by a uniformly sized vertically oriented dermal plug of laminated corneocytes with entrapped melanin and surrounding granulomatous inflammation, are likely derived from matrical or supramatrical cells (or both). | 20885284 |
| Inflammation | Altered Intercellular Communication | Confocal microscopy can detect subtle corneal changes in patients with CD, which may be signs of subclinical inflammation. | 20885311 |
| vascular inflammations | Altered Intercellular Communication | High blood pressure (BP) levels in African Americans elicit vascular inflammation resulting in vascular remodeling. | 20885987 |
| Inflammation, Electrocardiogram: myocardial infarction (finding) | Altered Intercellular Communication | We therefore aimed to investigate the relationship between prolactin, acute stress and inflammation in patients with myocardial infarction. | 20886416 |
| Necrotizing granulomatous inflammation | Altered Intercellular Communication | Microfibrillar collagen hemostat-induced necrotizing granulomatous inflammation developing after craniotomy: a pediatric case series. | 20887115 |
| Airway structure, ARCN1 gene, Chronic Obstructive Airway Disease | Altered Intercellular Communication | Airway inflammation is a known pathological feature of chronic obstructive pulmonary disease (COPD). | 20887348 |
| vascular inflammations | Altered Intercellular Communication | Deciphering STAT3 signaling in the heart: plasticity and vascular inflammation. | 20887622 |
| Inflammation, Heart failure, Hypertrophy | Altered Intercellular Communication | In this case, inflammation, aging, hypertrophy, and heart failure provide new environments that certainly impact on the functioning of STAT3 and on the gene profile linked to its activation. | 20887622 |
| Inflammation | Altered Intercellular Communication | Our data suggests that there are indeed age-dependent characteristics of culprit coronary plaque inflammation. | 20888054 |
| Inflammation, Dental Plaque | Altered Intercellular Communication | In particular, older subjects demonstrate a plaque phenotype with higher amounts of inflammation and lower levels of Treg cells. | 20888054 |
| Inflammation, Dental Plaque | Altered Intercellular Communication | Despite lower levels of inflammation, younger subjects also had fatal outcomes, indicating that alternative factors may be more important in plaque stability. | 20888054 |
| Pituitary Adenoma | Altered Intercellular Communication | Pituitary adenomas should be considered in the differential diagnosis of patients presenting with spontaneous CSF rhinorrhea with abnormal sellar image, and these patients should undergo a thorough hormonal evaluation. | 20888068 |
| Communicable Diseases, Fibrosis Assessment, Inflammation | Altered Intercellular Communication | Cystic fibrosis (CF) is characterised by impaired mucociliary clearance (MCC), chronic inflammation and infection, and progressively deteriorating lung function. | 20888307 |
| Inflammation, Fibrosis Assessment | Altered Intercellular Communication | The chitinase-like protein YKL-40 is a serum biomarker in diseases with fibrosis, inflammation and tissue remodelling. | 20888745 |
| Inflammation, Aortic Stiffness, Cerebrovascular accident | Altered Intercellular Communication | Our findings show that both aortic stiffness and wave reflection are related to the degree of systemic inflammation in stroke subjects, suggesting that circulating inflammation mediators can influence the stiffness of vessels distant to those involved in the disease process itself. | 20889155 |
| Inflammation | Altered Intercellular Communication | Because immunosuppressive agents are known to abate inflammation, we hypothesized the superior outcome of lower extremity bypass in renal transplant recipients compared with the hemodialysis population. | 20889298 |
| ARCN1 gene, Rhinovirus infection, Airway structure | Altered Intercellular Communication | After rhinovirus infection subjects with COPD developed lower respiratory symptoms, airflow obstruction, and systemic and airway inflammation that were greater and more prolonged compared with the control group. | 20889904 |
| Inflammation, Exacerbation | Altered Intercellular Communication | Impaired IFN production and neutrophilic inflammation may be important mechanisms in virus-induced COPD exacerbations. | 20889904 |
| Sepsis, Inflammation | Altered Intercellular Communication | Excessive inflammation is closely related to severity and outcome of sepsis. | 20890200 |
| ARCN1 gene, Inflammation, Pulmonary Hypertension | Altered Intercellular Communication | However, little information exists regarding the potential role of systemic inflammation in pulmonary hypertension of COPD. | 20890431 |
| Hepatitis | Altered Intercellular Communication | The platelet proteome was found highly responsive to each physiological stage of liver inflammation or pathogenesis. | 20919743 |
| Airway structure, Asthma | Altered Intercellular Communication | Exhaled nitric oxide (NO) is used as a surrogate marker to monitor eosinophilic airway inflammation, assist in diagnosis, and support treatment decisions for asthma patients. | 20920124 |
| Inflammation, Kidney Failure, Alport Syndrome, Hereditary | Altered Intercellular Communication | Alport syndrome (AS) is a rare inherited disorder characterized by an inflammation of the kidneys and damage to the glomerular capillaries, ultimately leading to renal failure at an early age. | 20920374 |
| Inflammation, Metabolic Syndrome X, Diabetes Mellitus | Altered Intercellular Communication | Relation of plasma fatty acid binding proteins 4 and 5 with the metabolic syndrome, inflammation and coronary calcium in patients with type-2 diabetes mellitus. | 20920650 |
| Inflammation, Disease, Atherosclerosis | Altered Intercellular Communication | Fatty acid-binding proteins (FABPs) 4 and 5 play coordinated roles in rodent models of inflammation, insulin resistance, and atherosclerosis, but little is known of their role in human disease. | 20920650 |
| Inflammation, Atherosclerosis | Altered Intercellular Communication | In correlation analysis, markers of nutrition, inflammation and atherosclerosis correlated well with m-BIA parameters. | 20921295 |
| palladium, Inflammation, Malnutrition, Atherosclerosis | Altered Intercellular Communication | FO defined by m-BIA is significantly correlated with markers of malnutrition, inflammation and atherosclerosis in PD patients. | 20921295 |
| vascular inflammations | Altered Intercellular Communication | Plasma pentraxin3 (PTX3), a marker of vascular inflammation, was also measured. | 20922537 |
| Inflammation, Corneal stromal edema | Altered Intercellular Communication | The diagnostic features that are useful in the recognition of this benign entity are the characteristic mixture of various architectural patterns, associated stromal edema and inflammation, hyaline sheath around tubules, eosinophilic colloidlike secretion within tubules, and lack of mitotic activity. | 20923300 |
| Inflammation, Malignant neoplasm of gallbladder | Altered Intercellular Communication | Conflicting results exist with regard to the prognostic significance of p21 and p53 expression, and the strong association of gallbladder cancer with chronic inflammation makes it only natural that COX2 negativity is rarely encountered, even in non-neoplastic biliary epithelia. | 20924037 |
| Inflammation, Colorectal Neoplasms | Altered Intercellular Communication | Flavonols, bioactive compounds found in plant-based foods and beverages, may inhibit colorectal neoplasms partly by attenuating inflammation. | 20924374 |
| Inflammation, Erythema | Altered Intercellular Communication | Given that her initial diagnosis was made with a sigmoidoscopy we scheduled a total colonoscopy showing marked inflammation, erythema and friability limited to the recto-sigmoid mucosa, like at the disease onset, and when we reached the cecum an erythematous area circumscribed to the appendiceal orifice was observed, with a mucosal aspect identical to the described for the recto-sigmoid mucosa. | 20924432 |
| Inflammation, Bacterial Infections | Altered Intercellular Communication | Presence of age-associated low-grade inflammation does not worsen the body response to bacterial infection in old male rats. | 20924673 |
| Inflammation | Altered Intercellular Communication | In the field of frailty, there is an underlying hypothesis that chronic low-grade inflammation contributes to bad outcomes in response to a stressor. | 20924673 |
| Communicable Diseases, Inflammation | Altered Intercellular Communication | The host response to an Escherichia coli infection was assessed in 24 month old male rats exhibiting a chronic low-grade inflammation and in non-inflamed control rats. | 20924673 |
| Inflammation, Weight decreased, Decreased Bone Tissue | Altered Intercellular Communication | The presence of chronic low-grade inflammation did not affect post-infection mortality, body weight loss and tissue mass decreases. | 20924673 |
| Inflammation, Bacterial Infections | Altered Intercellular Communication | Altogether, age-associated chronic low-grade inflammation in male rats did not worsen the body response to bacterial infection. | 20924673 |
| Inflammation | Altered Intercellular Communication | These results suggest that chronic low-grade inflammation is not an aggravating factor of the spiraling process leading to frailty. | 20924673 |
| Presenile dementia, Lewy Bodies, dendritic lamellar body, Hypoperfusion | Altered Intercellular Communication | Dementia with Lewy bodies (DLB) is often associated with occipital hypometabolism or hypoperfusion, as well as deficits in cholinergic neurotransmission. | 20924800 |
| ARCN1 gene, Airway structure, Chronic Obstructive Airway Disease, Asthma, Diabetes Mellitus, Non-Insulin-Dependent | Altered Intercellular Communication | Chronic airway inflammation in asthma or chronic obstructive pulmonary disease (COPD) may be involved in the pathogenesis of type 2 diabetes; however, prospective data have been limited. | 20926152 |
| ARCN1 gene, Airway structure, Diabetes Mellitus, Non-Insulin-Dependent, Diabetes Mellitus | Altered Intercellular Communication | Asthma and COPD were individually and independently associated with an increased risk of type 2 diabetes in women, indicating that chronic airway inflammation may contribute to diabetes pathogenesis. | 20926152 |
| Inflammation, Metabolic Syndrome X | Altered Intercellular Communication | We examined components of the metabolic syndrome, insulin resistance, a marker of inflammation, and the presence of painful comorbidities as possible mediators of this association. | 20926190 |
| Inflammation, Chronic pain, Obesity | Altered Intercellular Communication | After adjustment for insulin resistance, inflammation, and pain-related comorbidities, central obesity predicted higher TPI scores (OR 1.55, 95% CI 1.04-2.33) and nearly doubled the risk of chronic pain (OR 1.70, 95% CI 1.05-2.75). | 20926190 |
| Pain Distress Question, Inflammation, Neuropathy, Metabolic Syndrome X, Degenerative polyarthritis, Obesity | Altered Intercellular Communication | Central obesity is the metabolic syndrome component showing the strongest independent association with pain, and the relationship is not explained by markers of insulin resistance or inflammation, nor by the presence of osteoarthritis or neuropathy. | 20926190 |
| Inflammation, Peripheral Arterial Diseases | Altered Intercellular Communication | Hypoxia-inducible factor 1 (HIF1) is a key regulator of angiogenesis and is involved in inflammation, which are two important features of the pathogenesis of peripheral artery disease (PAD). | 20926496 |
| Inflammation, Neurogenic Inflammation, Cerebral dysfunction, Virus Diseases, Hepatitis C | Altered Intercellular Communication | As the increase of choline, creatine and myo-inositol are usually interpreted to indicate glial activation and macrophage infiltration in chronic inflammation and slow virus infections of the brain the present data endorse the hypothesis, that HCV infection may induce neuroinflammation and brain dysfunction. | 20926642 |
| Airway structure, asthma chronic | Altered Intercellular Communication | The T cell-driven airway inflammation in chronic asthma is uninhibited and sustained. | 20926789 |
| Rheumatoid Arthritis, Inflammatory abnormality of the eye, Psoriasis, Uveitis | Altered Intercellular Communication | We evaluated efficacy by measuring the psoriasis area and severity index (PASI), the American College of Rheumatology 20% response (ACR20) for rheumatoid arthritis, or the number of responders for uveitis, as defined by either vision improvement or reduction in ocular inflammation or corticosteroid dose. | 20926833 |
| Inflammation, Primary malignant neoplasm | Altered Intercellular Communication | Reciprocity of inflammation, oxidative stress and neovascularization is emerging as an important mechanism underlying numerous processes from tissue healing and remodelling to cancer progression. | 20927103 |
| Inflammation, Neoplasms, melanoma | Altered Intercellular Communication | Here we show that the end products of lipid oxidation, o-(2-carboxyethyl)pyrrole (CEP) and other related pyrroles, are generated during inflammation and wound healing and accumulate at high levels in ageing tissues in mice and in highly vascularized tumours in both murine and human melanoma. | 20927103 |
| Acromegaly, Cardiovascular Diseases, Malignant Neoplasms, Respiration Disorders | Altered Intercellular Communication | Acromegaly is characterized by chronic hypersecretion of growth hormone (GH) and is associated with increased mortality rate because of the potential complications such as cardiovascular disease, respiratory disease, or malignancy, which are probably caused by the long-term exposure of tissues to excess GH, for at least 10 years, before diagnosis and treatment. | 20930439 |
| Inflammation, Coronary Arteriosclerosis, Tissue injury | Altered Intercellular Communication | The complement system plays a major role in inflammation and tissue injury following myocardial ischemia and reperfusion (MI/R) injury. | 20930931 |
| Inflammation, Lymphohistiocytosis, Hemophagocytic, Systemic Vasculitis | Altered Intercellular Communication | After the inflammation and ANCA titers were resolved with steroid therapy for suspected microscopic polyangiitis, hemophagocytic syndrome developed. | 20931273 |
| Pharyngitis, Nasopharyngeal carcinoma | Altered Intercellular Communication | Methylation specific PCR revealed that 36.7% (11/30) of nasopharyngeal carcinoma tissues and all of the chronic nasopharyngeal inflammation samples were methylated. | 20932276 |
| Inflammation, Paronychia Inflammation | Altered Intercellular Communication | Retronychia is the phenomenon of ingrown nail resulting in inflammation of the proximal subungual fold and is a newly described entity. | 20932446 |
| Inflammation, Calcification of coronary artery | Altered Intercellular Communication | Inflammation, coronary artery calcification and cardiovascular events in incident renal transplant recipients. | 20934074 |
| Inflammation, "Alzheimers Disease", Cerebral Ischemia, Cerebrovascular accident | Altered Intercellular Communication | Triflusal reduces cerebral ischemia induced inflammation in a combined mouse model of Alzheimer's disease and stroke. | 20934412 |
| Infarction, Inflammation | Altered Intercellular Communication | Triflusal reduced inflammation surrounding the endothelin-induced infarct only. | 20934412 |
| Inflammation, Aortic Valve Stenosis | Altered Intercellular Communication | Inflammation is involved in the pathogenesis of nonrheumatic aortic valve stenosis (AS). | 20934563 |
| Inflammation, Asthma | Altered Intercellular Communication | This pathway is involved in immune responses to inflammation, including asthma. | 20934631 |
| Intraocular inflammation | Altered Intercellular Communication | One case of intraocular inflammation occurred >6 months after removal of perfluoro-n-octane tamponade. | 20934993 |
| Inflammation, Carcinogenesis | Altered Intercellular Communication | Chronic inflammation may be important in prostate carcinogenesis. | 20935064 |
| Intraocular inflammation, Choroiditis, Retinal vascular occlusion, Uveitis | Altered Intercellular Communication | In QuantiFERON-positive patients with severe uveitis forms, such as serpiginous choroiditis and occlusive retinal vasculitis, (18)F-FDG-PET/CT is useful to identify lesions appropriate for biopsy and helps to establish the diagnosis and appropriate therapy for presumed tuberculosis-induced intraocular inflammation. | 20935307 |
| Cerebral Amyloid Angiopathy, Inflammation | Altered Intercellular Communication | Cerebral amyloid angiopathy related inflammation: three case reports and a review. | 20935328 |
| Cerebral Amyloid Angiopathy, Inflammation, Encephalopathy, CTCAE 5.0 | Altered Intercellular Communication | Cerebral amyloid angiopathy related inflammation (CAA-I), previously described under various names, is a treatable encephalopathy usually occurring in older adults. | 20935328 |
| Inflammation, Epithelial metaplasia | Altered Intercellular Communication | Epithelial metaplasia and XG inflammation are often associated with GBC but do not appear to play a role in its pathogenesis through the p53 pathway. | 20935395 |
| Inflammation, Osteoporosis | Altered Intercellular Communication | While CRP, a systemic inflammation marker, is thought to be associated with osteoporosis, evidence supporting this claim has been limited. | 20936400 |
| Inflammation, Kyphosis deformity of spine | Altered Intercellular Communication | The SCH in AS might be caused by inflammation, and thoracolumbar hyperkyphosis results from AS might be associated with the development of SCH. | 20936535 |
| Airway structure, Asthma | Altered Intercellular Communication | Fractional exhaled nitric oxide (FeNO) has been proposed as a biomarker of airway inflammation for cohort studies of asthma. | 20936992 |
| Inflammation, Heartburn | Altered Intercellular Communication | There was a reduction in self-assessed symptoms of heartburn (P = 0.0005) and regurgitation (P < 0.0001), and inflammation and proliferation in the Barrett's mucosa. | 20937048 |
| Gastroesophageal reflux disease, Inflammation | Altered Intercellular Communication | High-dose esomeprazole achieved higher levels of gastric acid suppression and control of oesophageal acid reflux and symptoms, with significant decreases in inflammation and epithelial proliferation. | 20937048 |
| Inflammation, Neoplasm Metastasis, Congenital stenosis of esophagus | Altered Intercellular Communication | Secondary stenosis due to factors such as inflammation did not appear present, so congenital esophageal stenosis (CES) was diagnosed. | 20938113 |
| Inflammation, hepcidin, Anemia, Traumatic injury | Altered Intercellular Communication | Hepcidin in trauma: linking injury, inflammation, and anemia. | 20938270 |
| Inflammation, Wounds and Injuries, hepcidin | Altered Intercellular Communication | We sought to define the link between traumatic injury, hepcidin, and inflammation. | 20938270 |
| Inflammation, Obstruction, Pterygium Of Conjunctiva And Cornea, Astigmatism | Altered Intercellular Communication | Pterygium is a chronic fibrovascular overgrowth on the corneal surface and is often associated with inflammation, astigmatism and obstructed vision. | 20938674 |
| Cessation of life, Stomach Carcinoma | Altered Intercellular Communication | Gastric cancer (GC) is a second most common cause of cancer-related death and represents an inflammation-driven malignancy. | 20938721 |
| Inflammation, Dental Plaque, Atherosclerotic lesion | Altered Intercellular Communication | inflammation plays an essential role in the development and progression of atherosclerotic lesions and plaque disruption. | 20939703 |
| Communicable Diseases, Vesicovaginal Fistula, Inflammation | Altered Intercellular Communication | Considering possible infection and inflammation remaining, we decided to perform abdominal repair of the vesicovaginal fistula about three months after the operation. | 20940528 |
| Colitis | Altered Intercellular Communication | DSS mice also had smaller testes, lower FSH levels, increased systemic cytokines, and increased colonic inflammation by histology. | 20940665 |
| Inflammation, Acidemia, Hypercapnia | Altered Intercellular Communication | Laboratory findings revealed mild inflammation, mild acidemia, and hypercapnea with radiologic infiltrations in the right lung, and remarkable wheezes in both lungs were heard on auscultation. | 20941521 |
| Inflammation | Altered Intercellular Communication | Primary inflammation of an epiploic appendix of the ascending colon. | 20941981 |
| Inflammation, atherosclerotic | Altered Intercellular Communication | Inflammation plays a crucial role in the development and progression of atherosclerotic plaques. | 20943047 |
| Structure of suprasellar region, Sarcoidosis, Non-necrotizing granulomatous inflammation | Altered Intercellular Communication | Open biopsy of the suprasellar mass showed non-caseating chronic granulomatous inflammation compatible with sarcoidosis. | 20943117 |
| Inflammation, Structure of posterior cerebral artery | Altered Intercellular Communication | Mounting evidence has revealed that chronic inflammation can be an important initiating factor of PCa. | 20943438 |
| Inflammation, Pancreatic Intraductal Papillary Mucinous Neoplasm, Adenocarcinoma of pancreas | Altered Intercellular Communication | The role of inflammation in patients with intraductal mucinous neoplasm of the pancreas and in those with pancreatic adenocarcinoma. | 20944173 |
| Inflammation, Pancreatic Intraductal Papillary Mucinous Neoplasm | Altered Intercellular Communication | There are very few data regarding inflammation in patients with intraductal papillary mucinous neoplasms (IPMNs) of the pancreas. | 20944173 |
| Inflammation, Hypertension, CTCAE, Obesity, Atherosclerosis | Altered Intercellular Communication | The relationship between inflammation, obesity and risk for hypertension in the Multi-Ethnic Study of Atherosclerosis (MESA). | 20944659 |
| Inflammation, Hypertension, CTCAE | Altered Intercellular Communication | It has been suggested that inflammation is important in the aetiology of hypertension and that this may be most relevant among obese persons. | 20944659 |
| Hypertension, CTCAE | Altered Intercellular Communication | The relationship between inflammation-related proteins and hypertension risk was predominantly explained by other hypertension risk factors. | 20944659 |
| Inflammation, Hypertension, CTCAE, Obesity | Altered Intercellular Communication | Obesity, independent of inflammation, remained a potent risk factor for future hypertension. | 20944659 |
| Autoinflammatory Syndrome, Inflammation, Neoplasm Metastasis, Rheumatoid Arthritis, Inflammatory disorder, Tenosynovitis | Altered Intercellular Communication | It is called inflammatory Brown syndrome, a secondary disorder, which main causes are local inflammation in the orbit and inflammatory diseases such as rheumatoid arthritis and tenosynovitis. | 20944946 |
| Inflammation, Sleep Apnea, Obstructive | Altered Intercellular Communication | The mechanisms by which OSAS can affect the cardiovascular system are multiple, including the activation of the sympathetic nervous system, systemic inflammation, insulin resistance, and oxidative stress. | 20944980 |
| Inflammation, Atrial Fibrillation, Atrial Fibrillation by ECG Finding | Altered Intercellular Communication | Inflammation and oxidative stress are associated with atrial fibrillation (AF). | 20946227 |
| Atrial Fibrillation, Inflammation | Altered Intercellular Communication | We tested if atorvastatin reduced AF recurrence after DC cardioversion (CV) by modifying systemic oxidative stress and inflammation (NCT00252967). | 20946227 |
| Inflammation | Altered Intercellular Communication | It reduced selective markers of inflammation without affecting systemic oxidative stress. | 20946227 |
| Kidney Failure, Chronic, Inflammation, Cyclophosphamide/Vincristine/Dacarbazine Regimen, Cardiovascular Diseases | Altered Intercellular Communication | Hemodiafiltration with regeneration of ultrafiltrate (HFR) has a positive impact on inflammation and oxidative stress (OxSt), risk factors for cardiovascular disease (CVD), the most common cause of excess morbidity and mortality for end-stage renal disease (ESRD) patients. | 20946294 |
| Inflammation, Cyclophosphamide/Vincristine/Dacarbazine Regimen, atherosclerotic | Altered Intercellular Communication | Given the strong relationships between OxSt and inflammation with CVD, their reduction might provide a beneficial impact by reducing the risk of atherosclerotic CVD in dialysis patients. | 20946294 |
| Hyperthyroidism, Inflammation, Neoplasms, Hypothyroidism | Altered Intercellular Communication | In order to achieve better orientation in the processing of results, the patient-described types of disorders were classified according to the patients' own opinions into the following groups: eufunctional thyroid gland, inflammation, hypothyroidism, hyperthyroidism, tumour and surgery. | 20946722 |
| Inflammation, Diabetes Mellitus | Altered Intercellular Communication | Oxidative conditions such as inflammation and diabetes are the major determinants of FORT values in patients with AMI. | 20947086 |
| Data types - Address | Altered Intercellular Communication | Our findings suggest that reduced inhibitory neurotransmission during aging and in AD may be the result of compensatory responses that, paradoxically, render the neurons vulnerable to Ca(2+)-mediated degeneration. | 20947216 |
| Communicable Diseases, Inflammation, Traumatic injury, Malignant Neoplasms | Altered Intercellular Communication | Pathologic processes presenting with limping include trauma, inflammation, infection, and malignancy. | 20947283 |
| ARCN1 gene, Inflammation, Atherosclerosis, Chronic Obstructive Airway Disease, Endothelial dysfunction | Altered Intercellular Communication | The relationship between chronic obstructive pulmonary disease (COPD) and atherosclerosis has been suggested; this association may relate to systemic inflammation and endothelial dysfunction, which can lead to alteration of small pulmonary vessels. | 20947389 |
| Inflammation, Endothelial dysfunction, Atherosclerosis | Altered Intercellular Communication | Systemic inflammation and endothelial dysfunction may cause the close relationship between atherosclerosis and small pulmonary vessel alteration. | 20947389 |
| ARCN1 gene, Chronic Obstructive Airway Disease, Pneumonitis | Altered Intercellular Communication | Seven patients with chronic obstructive pulmonary disease (COPD) and three patients with acute lung inflammation served as control groups. | 20947455 |
| ARCN1 gene, Pneumonitis | Altered Intercellular Communication | Lactate was lower (1.6+-0.8mmol/L) in sputa from seven COPD patients, and it was below the detection limit in three patients with acute lung inflammation. | 20947455 |
| Adenocarcinoma, Neoplasms | Altered Intercellular Communication | We measured the expression of 23 inflammation-associated genes in tumors and adjacent normal tissues from 93 patients (58 Barrett's and 35 Sporadic adenocarcinomas) by quantitative reverse transcription-polymerase chain reaction. | 20947516 |
| Inflammation, Pleural effusion disorder | Altered Intercellular Communication | Thrombin-antithrombin III complex, proinflammatory cytokines, and fibrinolytic indices for assessing the severity of inflammation in pleural effusions. | 20947808 |
| Inflammation, Pleural effusion disorder | Altered Intercellular Communication | In conclusion, TNF-a and PAI-1 are important indicators in patients with tuberculous pleural effusions, and measurement of TAT is useful for assessing the severity of inflammation in pleural fluids. | 20947808 |
| Inflammation, Headache | Altered Intercellular Communication | Headache due to the pressure of nasal mucosa in the absence of inflammation of the nose and paranasal sinuses is a clinical entity that has gained wide acceptance. | 20948593 |
| Inflammation | Altered Intercellular Communication | Histology revealed hypodermic granulomatous inflammation with predominantly macrophage and eosinophils. | 20949344 |
| Granulomatous inflammation, Blastomycosis, Mycoses | Altered Intercellular Communication | Fine-needle aspiration of the thyroid demonstrated 10-20 mm broad-based budding yeasts with thick-walled, refractile capsules amidst a background of granulomatous inflammation, and was diagnosed as a fungal infection consistent with blastomycosis. | 20949466 |
| Granulomatous inflammation | Altered Intercellular Communication | Fungal and mycobacterial cultures and special stains for fungal organisms should be requested on all thyroid fine-needle aspiration biopsies with granulomatous inflammation. | 20949466 |
| Inflammation, Weight decreased | Altered Intercellular Communication | Our findings did not provide any evidence for a role of visfatin increase on low-grade inflammation after weight loss. | 20951014 |
| Inflammation, Atherosclerosis | Altered Intercellular Communication | Resistin is an adipocytokine involved in insulin resistance, inflammation, and atherosclerosis. | 20951381 |
| Inflammation, Choline Dehydrogenase, Mitochondrial | Altered Intercellular Communication | Adjustment for inflammatory markers attenuated these associations, suggesting a possible role for resistin in inflammation and CHD pathophysiology. | 20951381 |
| Inflammation | Altered Intercellular Communication | Chronic and acute stress, with associated pathophysiology, are implicated in a variety of disease states, with neuroimmunological dysregulation and inflammation as major hazards to health and functional sufficiency. | 20953749 |
| Inflammation | Altered Intercellular Communication | Chronic conditions of stress and affective dysregulation are associated with neuroimmunological insufficiency and inflammation, contributing to health risk and mortality. | 20953749 |
| Inflammation, Fibrosis Assessment, Hepatitis | Altered Intercellular Communication | Moreover, they had more advanced fibrosis, portal inflammation, interface hepatitis, and proliferation of bile ductules (P = 0.008, P = 0.008, P = 0.019, and P = 0.027, respectively). | 20954280 |
| Inflammation, Fibrosis Assessment, Hepatitis | Altered Intercellular Communication | ANEA positive, anti-gp210 negative patients had a difference in AMA titer (<= 1:160/> 1:160 50%/50% vs 71.8%/28.2%, P = 0.002), stage (I-II/III-IV 57.9%/42.1% vs 74.4%/25.6%, P = 0.033), fibrosis (P = 0.009), portal inflammation (P = 0.018), interface hepatitis (P = 0.032), and proliferation of bile ductules (P = 0.031). | 20954280 |
| Inflammation, Carcinoma of lung, Neoplasms | Altered Intercellular Communication | There is emerging evidence that chronic inflammation may play a significant role in the pathogenesis of lung cancer as a tumor promoter. | 20954376 |
| Heart Diseases, Inflammation, Cerebrovascular accident | Altered Intercellular Communication | Reduced albumin may be a marker of chronic systemic inflammation, which may be the mechanism for cardiopathy and bad outcome of stroke. | 20954836 |
| Inflammation, Erectile dysfunction | Altered Intercellular Communication | Previous studies have suggested that erectile dysfunction (ED) is associated with chronic inflammation, which is also a principle mechanism of carcinogensis. | 20955312 |
| Inflammation, Hypercholesterolemia | Altered Intercellular Communication | Our results indicate that low-grade systemic inflammation and monocyte secretory function are disturbed to a similar degree in the patients with isolated hypercholesterolaemia and in the patients with IFG. | 20955358 |
| Inflammation, Thrombosis | Altered Intercellular Communication | In the current case, the factors possibly associated with increased risk for dissection may include dilatation of the pulmonary artery, local inflammation favoured by in situ thrombosis, and acute increase of pulmonary pressure secondary to physical exertion. | 20956141 |
| Malignant mesothelioma, Inflammation | Altered Intercellular Communication | Asbestos-induced chronic inflammation is implicated in the pathogenesis of malignant mesothelioma (MM). | 20956618 |
| Periodontal Diseases, Inflammation, Endothelial dysfunction | Altered Intercellular Communication | Treatment of periodontal disease may reduce cardiovascular risk in the longer term, but studies have suggested a link among dental procedures, acute inflammation, and endothelial dysfunction. | 20956706 |
| Stomach Carcinoma, Communicable Diseases, Helicobacter pylori, Inflammation | Altered Intercellular Communication | Gastric cancer commonly follows a long-standing inflammation, mainly due to Helicobacter pylori (HP) infection. | 20956764 |
| Degenerative polyarthritis, Pain Distress Question, Inflammation | Altered Intercellular Communication | To assess experimental pain sensitivity and compare the inflammatory response to pain in 26 osteoarthritis (OA) patients and 33 age- and sex-matched controls from the general population in order to examine the nature of the association between pain and inflammation in OA. | 20957660 |
| Autoimmune Diseases, Inflammation, Primary malignant neoplasm | Altered Intercellular Communication | Apart from a significant increase in our understanding of the mechanisms for uptake, cell clearance is a basic mechanism in tissue homeostasis, cancer, resolution of inflammation, induction of tolerance, and autoimmunity. | 20958309 |
| Acidophil Stem Cell Pituitary Gland Adenoma, Acromegaly, Neoplasms | Altered Intercellular Communication | Fugitive acromegaly is most commonly caused by pituitary acidophil stem cell adenomas, and is characterized by a relatively short clinical history, a large and locally invasive tumor, and relatively low hormonal activity. | 20960094 |
| Inflammation | Altered Intercellular Communication | The systemic inflammation induced by common cytokines may explain the linkage between the two conditions. | 20960105 |
| Inflammation, Neck Pain | Altered Intercellular Communication | Case report of an 85-year-old patient with acute neck pain and elevated parameters of inflammation in the blood. | 20960401 |
| Inflammation | Altered Intercellular Communication | S. aureus may play an important role in the pathogenesis of NP via tissue remodeling as well as eosinophilic inflammation. | 20961499 |
| Inflammation, Metabolic Syndrome X, Cardiovascular Diseases, Restless Legs Syndrome, Obesity, Hypertension, CTCAE | Altered Intercellular Communication | RLS was not associated with symptoms of the metabolic syndrome like hypertension, obesity, markers of systemic inflammation (IL-6 and CRP) or cardiovascular diseases. | 20961808 |
| Inflammation, Metabolic Syndrome X, Cardiovascular Diseases, Restless Legs Syndrome, Obesity, Hypertension, CTCAE | Altered Intercellular Communication | RLS was not associated with markers of the metabolic syndrome like hypertension, obesity, cardiovascular diseases or biomarkers of systemic inflammation. | 20961808 |
| Inflammation, Diarrhea, Helminths | Altered Intercellular Communication | We measured changes in hemoglobin concentrations, inflammation, iron status, helminths, diarrhea, fecal calprotectin concentrations, and microbiota diversity and composition (n = 60) and the prevalence of selected enteropathogens. | 20962160 |
| Inflammation | Altered Intercellular Communication | Thus, iron fortification in this population produces a potentially more pathogenic gut microbiota profile, and this profile is associated with increased gut inflammation. | 20962160 |
| Autoimmune Diseases, Inflammation | Altered Intercellular Communication | Regulatory B cells control inflammation and autoimmunity in mice, including the recently identified IL-10-competent B10 cell subset that represents 1% to 3% of spleen B cells. | 20962324 |
| Inflammation, Ulcerative Colitis | Altered Intercellular Communication | However, the frequency and types of inflammation in upper gastrointestinal biopsies in patients with UC has not been well studied, especially in a controlled study. | 20962621 |
| Gastritis, Ulcerative Colitis | Altered Intercellular Communication | There were 3 types of gastric inflammation that occurred more in UC patients than in controls, and the differences were statistically significant. | 20962621 |
| Inflammation, Ulcerative Colitis, Plasmacytosis | Altered Intercellular Communication | Twenty-two percent of UC patients had a basal mixed inflammation compared with 8% of controls, and 20% of the UC patients had superficial plasmacytosis compared with 6% of controls. | 20962621 |
| Ulcerative Colitis | Altered Intercellular Communication | Most UC patients have no upper gastrointestinal inflammation in biopsies, and most of the inflammations they have are not unique. | 20962621 |
| Inflammation, Ulcerative Colitis, Gastritis, Plasmacytosis | Altered Intercellular Communication | The most common upper gastrointestinal inflammatory pattern in patients with UC is focal gastritis, followed by gastric basal mixed inflammation and superficial plasmacytosis. | 20962621 |
| Pouchitis, Duodenitis, Gastrointestinal inflammation, Ulcerative Colitis | Altered Intercellular Communication | The one unique upper gastrointestinal inflammation in UC patients is diffuse chronic duodenitis, present in 10% of patients who had duodenal biopsies, and in 40% of UC patients who had colectomy and all of these patients had pouchitis. | 20962621 |
| Esophagitis, Ulcerative Colitis | Altered Intercellular Communication | There were no esophageal inflammations that occurred more commonly in UC than controls. | 20962621 |
| Ulcerative Colitis | Altered Intercellular Communication | Most UC patients have no upper gastrointestinal inflammation in biopsies, and most of the inflammations they have are not unique. | 20962621 |
| Nephritis, Kidney Diseases | Altered Intercellular Communication | This suggested that intrarenal inflammation might accelerate Alport nephropathy. | 20962742 |
| Nephritis | Altered Intercellular Communication | Thus, systemic exposure to CpG-DNA induces classically activated (M1) macrophages that enhance intrarenal inflammation and disease progression. | 20962742 |
| Arterial Stiffness, Inflammation, Antihypertensive Agents | Altered Intercellular Communication | The diverse associations of uric acid with low-grade inflammation, adiponectin and arterial stiffness in never-treated hypertensives. | 20962858 |
| Hypertensive disease, Inflammation | Altered Intercellular Communication | The data regarding the role of serum uric acid (SUA) along with subclinical inflammation in the context of hypertensive vascular damage are rather scarce and controversial. | 20962858 |
| Inflammation, Atherosclerosis, Diabetes Mellitus, Chronic disease, Malignant Neoplasms | Altered Intercellular Communication | Chronic inflammation has been implicated in the pathogenesis of several chronic diseases, such as atherosclerosis and diabetes, as well as certain types of cancers. | 20962912 |
| Inflammation | Altered Intercellular Communication | It has been suggested that circulating biomarkers for inflammation may be modified by exercise; however, few laboratory-based studies have been conducted in nonobese premenopausal women. | 20962912 |
| Inflammation | Altered Intercellular Communication | Macrophage staining for PON1 and PON3 was significantly and positively related to the amount of aortic inflammation (both P<0*001). | 20964682 |
| Inflammation, Autonomic nervous system disorders | Altered Intercellular Communication | Inflammation, platelet reactivity and cardiac autonomic dysfunction increase the risk of cardiovascular events, but the relationships between these prognostic markers are poorly defined. | 20964738 |
| Inflammation, Weight decreased, Fracture | Altered Intercellular Communication | The final outcomes of this trial will assist clinicians in the development of effective and alternative treatment methods post proximal femoral fracture surgery which may ultimately result in a reduction in systemic inflammation, loss of weight and lean muscle and improvements in nutritional status, mobility, independence and quality of life among elderly patients. | 20964865 |
| Inflammation, Coronary Arteriosclerosis | Altered Intercellular Communication | Results suggest that exposure to quasi-ultrafine particles and combustion-related pollutants (predominantly from traffic) increase the risk of myocardial ischemia, coherent with our previous findings for systemic inflammation and blood pressure. | 20965803 |
| Coughing, Airway structure | Altered Intercellular Communication | Previous work has suggested that cough may be linked to neutrophilic airway inflammation. | 20965928 |
| Inflammation, Atrial Fibrillation by ECG Finding | Altered Intercellular Communication | Inflammation may play a significant role in the pathogenesis of atrial fibrillation (AF). | 20965978 |
| Inflammation, Fibrosis Assessment, Lung diseases | Altered Intercellular Communication | After a 27-year interval, two subjects with manifestations of preclinical familial pulmonary fibrosis, including asymptomatic alveolar inflammation and alveolar macrophage activation, were reevaluated for lung disease. | 20966039 |
| Inflammation, Fibrosis Assessment, Lung diseases, Kidney Failure | Altered Intercellular Communication | In familial pulmonary fibrosis, asymptomatic preclinical alveolar inflammation associated with mutation in TERT and telomerase insufficiency can progress to fibrotic lung disease over 2 to 3 decades. | 20966039 |
| Airway structure, Pulmonary Emphysema | Altered Intercellular Communication | Persistent airway inflammation and emphysema progression on CT scan in ex-smokers observed for 4 years. | 20966041 |
| Airway structure | Altered Intercellular Communication | Whether discontinuing smoking for at least 4 years halts airway inflammation and progression of COPD-E in prior smokers is unknown. | 20966041 |
| Airway structure | Altered Intercellular Communication | Cessation of tobacco smoking in heavy smokers with moderately severe COPD-E is associated with evidence of persistent airway inflammation and progression of COPD-E on CT scan 4 years later. | 20966041 |
| Airway structure | Altered Intercellular Communication | Discontinuing smoking may slow the rate of progression of moderate severity COPD-E, but it does not prevent persistent airway inflammation and significant progression of COPD-E on CT scan. | 20966041 |
| Inflammation, Fibrosis Assessment, Endothelial dysfunction, Hypertrophy, Cardiovascular system | Altered Intercellular Communication | Cardiovascular signs included increased systolic blood pressure and endothelial dysfunction together with inflammation, fibrosis, hypertrophy, increased stiffness, and delayed repolarization in the left ventricle of the heart. | 20966763 |
| Inflammation, Fibrosis Assessment | Altered Intercellular Communication | The liver showed increased wet weight, fat deposition, inflammation, and fibrosis with increased plasma activity of liver enzymes. | 20966763 |
| Inflammation, Fibrosis Assessment | Altered Intercellular Communication | The kidneys showed inflammation and fibrosis, whereas the pancreas showed increased islet size. | 20966763 |
| Intestinal metaplasia, Inflammation, Gastritis, Atrophic | Altered Intercellular Communication | Histological assessment showed alleviation of chronic inflammation in all subjects (p < 0.0001), while such a change was not observed for four subjects showing severe gastric atrophy and intestinal metaplasia. | 20967557 |
| Inflammatory Bowel Diseases, Inflammation | Altered Intercellular Communication | Downregulation of serum EGF may be correlated with different patterns of bowel inflammation, epithelial development, and wound healing in IBD. | 20969541 |
| Chronic Kidney Diseases | Altered Intercellular Communication | Posttransplant inflammation associated with onset of chronic kidney disease. | 20970563 |
| Inflammation, Tumor necrosis | Altered Intercellular Communication | The following markers of inflammation (MIF) were determined pretransplant and at 3 months after grafting: C-reactive protein (CRP) (mg/L), interleukin (IL)-6 (pg/mL), IL-10 (pg/mL), tumor necrosis factor (TNF)-a (pg/mL), and its soluble receptor (ng/mL), soluble-IL2R (UI/mL), pregnancy-associated plasma protein A (PAPP-A; mUI/L), and IL-4 (pg/mL). | 20970563 |
| Inflammation, Canada | Altered Intercellular Communication | Patients with CAN showed worse inflammation, eg, MIF ratios over one, with statistically significant differences for the ratios of TNF-a and PAPP-A (P=.032 and P=.051 respectively). | 20970563 |
| Inflammation, Canada | Altered Intercellular Communication | Among other factors, inflammation may determine the onset of CAN as diagnosed by renal biopsy. | 20970563 |
| Inflammation, Carotid Atherosclerosis | Altered Intercellular Communication | Inflammation, metalloproteinases, and growth factors in the development of carotid atherosclerosis in renal transplant patients. | 20970566 |
| ARCN1 gene, Inflammation, Chronic Obstructive Airway Disease | Altered Intercellular Communication | Chronic obstructive pulmonary disease (COPD) is associated with neutrophil-mediated inflammation, a potential target for treatment in COPD. | 20970976 |
| Keratoconjunctivitis, Vernal, allergic inflammation | Altered Intercellular Communication | Vernal keratoconjunctivitis (VKC) is a recurrent, chronic allergic inflammation of the ocular surface associated with remodeling of the cornea and conjunctiva, with a potential to adversely affect the patient's vision and quality of life. | 20971677 |
| Inflammation, destruction joint, Arthritis | Altered Intercellular Communication | Silencing the expression of Ras family GTPase homologues decreases inflammation and joint destruction in experimental arthritis. | 20971740 |
| Inflammation, destruction joint, Arthritis | Altered Intercellular Communication | The overlap in contributions of Ras homologues to FLS activation suggests that broad targeting of Ras GTPases in vivo suppresses global inflammation and joint destruction in arthritis. | 20971740 |
| Inflammation, destruction joint, Arthritis, Collagen-Induced | Altered Intercellular Communication | Consistent with this, simultaneous silencing of H-Ras, K-Ras, and N-Ras expression significantly reduces inflammation and joint destruction in murine collagen-induced arthritis, while specific targeting of N-Ras alone is less effective in providing clinical benefits. | 20971740 |
| Inflammation, Intracranial Aneurysm, Rupture | Altered Intercellular Communication | Inflammation and activation of the complement system predispose to intracranial artery aneurysm (IA) rupture. | 20971742 |
| Experimental Organism Luteinized Unruptured Follicle, Inflammation, Rupture | Altered Intercellular Communication | Because disturbances in complement regulation may lead to increased susceptibility to complement activation and inflammation, we looked for evidence for dysregulation of the complement system in 26 unruptured and 26 ruptured IAs resected intraoperatively. | 20971742 |
| Tissue damage, Inflammation | Altered Intercellular Communication | Apparently, disturbed complement regulation leads to an increased susceptibility to complement activation, inflammation, and tissue damage in the IA wall. | 20971742 |
| Inflammation, Ulcerative Colitis, interferon beta-1a | Altered Intercellular Communication | Suppression of inflammation in ulcerative colitis by interferon-b-1a is accompanied by inhibition of IL-13 production. | 20971977 |
| Inflammation, Atherosclerosis | Altered Intercellular Communication | While it is well documented that inflammation is an important risk factor for vascular pathophysiology, the association of bacteria with atherosclerosis has not been clearly established, in large part due to the inability to isolate live bacteria from atheromatous tissue. | 20972353 |
| Inflammation, Dental Plaque | Altered Intercellular Communication | Characterization of carotid artery plaques with USPIO-enhanced MRI: assessment of inflammation and vascularity as in vivo imaging biomarkers for plaque vulnerability. | 20972832 |
| Dermatitis, Atopic, Inflammation, Data types - Address | Altered Intercellular Communication | A subgroup of patients with atopic dermatitis (AD) produces IgE autoantibodies to human proteins which may be present in inflamed skin and perpetuate cutaneous inflammation. | 20973764 |
| Inflammation, Data types - Address | Altered Intercellular Communication | These TCC produce not only Th2 but also Th1 cytokines which may explain the Th1 phenotype of inflammation in AD. | 20973764 |
| Inflammation, Benign prostatic hypertrophy | Altered Intercellular Communication | A retrospective study: correlation of histologic inflammation in biopsy specimens of Chinese men undergoing surgery for benign prostatic hyperplasia with serum prostate-specific antigen. | 20974483 |
| Inflammation, Benign prostatic hypertrophy | Altered Intercellular Communication | To reveal the correlation between benign prostatic hyperplasia (BPH) histologic inflammation and serum prostate-specific antigen (sPSA) concentrations, and the possible mechanism. | 20974483 |
| Inflammation, Leucocytic infiltrate, prostatitis | Altered Intercellular Communication | According to the histopathological classification system for chronic prostatic inflammation proposed by the Chronic Prostatitis Collaborative Research Network (CPCRN) and the International Prostatitis Collaborative Network (IPCN), we classified the histologic sections of prostatic biopsy into glandular, periglandular, and stromal inflammation by the anatomical location of inflammatory infiltration. | 20974483 |
| Inflammation, Aggressive behavior | Altered Intercellular Communication | The glandular inflammation was graded according to the inflammatory aggressiveness. | 20974483 |
| Inflammation | Altered Intercellular Communication | The periglandular and stromal inflammation were graded according to the inflammatory density. | 20974483 |
| Inflammation | Altered Intercellular Communication | Single regression analysis revealed that total prostatic volume, the aggressiveness of glandular inflammation, and the intensity of periglandular and stromal inflammation were correlated with sPSA. | 20974483 |
| Inflammation, Primary malignant neoplasm, Neoplasms | Altered Intercellular Communication | Alkylation of the tumor suppressor PTEN activates Akt and b-catenin signaling: a mechanism linking inflammation and oxidative stress with cancer. | 20975834 |
| Inflammation, Hyperplasia, Neoplastic disease | Altered Intercellular Communication | Alkylation of PTEN by a,b-enals/enones and interference with its restraint of cellular PKB/Akt signaling may accentuate hyperplastic and neoplastic disorders associated with chronic inflammation, oxidative stress, or aging. | 20975834 |
| Colorectal Carcinoma | Altered Intercellular Communication | Comparison of positive lymph node ratio with an inflammation-based prognostic score in colorectal cancer. | 20976703 |
| Colorectal Carcinoma | Altered Intercellular Communication | Two prognostic scoring systems have been proposed in colorectal cancer: the pathologically based positive lymph node ratio (pLNR) and the inflammation-based modified Glasgow Prognostic Score (mGPS). | 20976703 |
| Neuronal loss in central nervous system, MS gene, Meningitis | Altered Intercellular Communication | A Gradient of neuronal loss and meningeal inflammation in multiple sclerosis. | 20976767 |
| Inflammation, MS gene | Altered Intercellular Communication | Prominent inflammation with formation of ectopic B-cell follicle-like structures in the meninges in secondary progressive multiple sclerosis (MS) (SPMS) is associated with extensive cortical pathology and an exacerbated disease course. | 20976767 |
| Damage, Meningitis | Altered Intercellular Communication | Our objective was to evaluate the cellular substrates of the cortical damage to understand the role of meningeal inflammation in MS pathology. | 20976767 |
| Loss, Nerve Degeneration, Meningitis | Altered Intercellular Communication | We demonstrate substantial cortical neurodegeneration and generalized cell loss in progressive MS in association with meningeal inflammation and lymphoid tissue formation, supporting the hypothesis that cytotoxic factors diffusing from the meningeal compartment contribute to grey matter pathology and the consequent increase in clinical disability. | 20976767 |
| Inflammation, Infection | Altered Intercellular Communication | As the disease progresses, frequent infections and inflammation initiate destruction of the parenchyma leading to chronic obstruction of the airways. | 20977128 |
| Asthma, Bronchitis | Altered Intercellular Communication | Fractional exhaled nitric oxide (FeNO) is a non-invasive marker of bronchial inflammation in asthma. | 20977500 |
| Bronchitis | Altered Intercellular Communication | Optimal clinical control of infantile wheeze appeared to be associated with the control of bronchial inflammation when evaluated by FeNO measurements. | 20977500 |
| Inflammation | Altered Intercellular Communication | Further characterization of common and lower-frequency genetic variants that contribute to interpopulation differences in fibrinogen phenotype may help refine our understanding of the contribution of hemostasis and inflammation to atherothrombotic risk. | 20978265 |
| Inflammation, Asthma | Altered Intercellular Communication | Leptin levels correlated with the clinical severity of asthma and this was suggested to be associated with the severity of inflammation in asthma. | 20978869 |
| Inflammation, Pneumonia | Altered Intercellular Communication | In this patient, the increased circulating cortisol associated with the stress of inflammation caused by pneumonia triggered the development of pseudoaldosteronism. | 20979951 |
| Superficial ulcer, Rheumatoid Arthritis, Inflammation | Altered Intercellular Communication | No overall progression and occasional repair of erosions despite persistent inflammation in adalimumab-treated rheumatoid arthritis patients: results from a longitudinal comparative MRI, ultrasonography, CT and radiography study. | 20980282 |
| Refractory anemias, Inflammation, Rheumatoid Arthritis, Destruction (action) | Altered Intercellular Communication | To monitor joint inflammation and destruction in rheumatoid arthritis (RA) patients receiving adalimumab/methotrexate combination therapy using MRI and ultrasonography. | 20980282 |
| Inflammation, Edema | Altered Intercellular Communication | Inflammation on MRI and ultrasonography, especially MRI bone oedema, was predictive for erosive progression on CT, at bone/joint level and MRI bone oedema also at patient level. | 20980282 |
| Inflammation | Altered Intercellular Communication | Insufficient role of cell proliferation in aberrant DNA methylation induction and involvement of specific types of inflammation. | 20980348 |
| Inflammation | Altered Intercellular Communication | Chronic inflammation is deeply involved in induction of aberrant DNA methylation, but it is unclear whether any type of persistent inflammation can induce methylation and how induction of cell proliferation is involved. | 20980348 |
| Inflammation, Helicobacter, Neutrophil Infiltration | Altered Intercellular Communication | After 20 weeks, chronic inflammation with lymphocyte and macrophage infiltration was prominent in the three Helicobacter groups, whereas neutrophil infiltration was mainly observed in the EtOH and NaCl groups. | 20980348 |
| Helicobacter | Altered Intercellular Communication | Among the inflammation-related genes, Il1b, Nos2 and Tnf showed increased expression specifically in the three Helicobacter groups. | 20980348 |
| Communicable Diseases, Helicobacter, Inflammation | Altered Intercellular Communication | These data showed that inflammation due to infection of the three Helicobacter strains has a strong potential to induce methylation, regardless of their CagA statuses, and increased cell proliferation was not sufficient for methylation induction. | 20980348 |
| Inflammation | Altered Intercellular Communication | It was suggested that specific types of inflammation characterized by expression of specific inflammation-related genes, along with increased cell proliferation, are necessary for methylation induction. | 20980348 |
| Inflammation, Chronic Kidney Diseases | Altered Intercellular Communication | Reduced vitality and enhanced ECC formation suggest growth induction of impaired EPCs in chronic renal failure and are associated with inflammation. | 20980359 |
| Inflammation, Arthritis, Psoriatic | Altered Intercellular Communication | Inflammation in an individual joint predicts damage to that joint in psoriatic arthritis. | 20980703 |
| Inflammation, Primary malignant neoplasm | Altered Intercellular Communication | Systemic inflammation (SI) plays a pivotal role in cancer. | 20981494 |
| Inflammation, Atherosclerosis | Altered Intercellular Communication | The renin angiotensin aldosterone system (RAAS) induces inflammation and accelerates atherosclerosis, contributes to both pro- and anti-inflammatory cytokines. | 21028999 |
| Inflammation | Altered Intercellular Communication | C-reactive protein (CRP) not only reflects an inflammatory state but also leads to inflammation. | 21028999 |
| Inflammation, Sialectasia NOS | Altered Intercellular Communication | The clinical criteria applied included the coexistence of multiple lesions and mucoid/purulent discharge, while the histopathological criteria included two or more of the following findings: sialectasia, chronic inflammation, mucous/oncocytic metaplasia and mucin in ducts. | 21029266 |
| Cerebrovascular Disorders, Inflammation | Altered Intercellular Communication | Influence of prophylactic, endovascularly based normothermia on inflammation in patients with severe cerebrovascular disease: a prospective, randomized trial. | 21030704 |
| Inflammation, Hyperplasia | Altered Intercellular Communication | The present results arouse suspicion of local inflammation of the aortic wall, but with moderate progress under strong hyperplasia. | 21030919 |
| Rupture, Inflammation, Acute Disease | Altered Intercellular Communication | Because of rupture of the intima, the inflammation appears as an acute disease. | 21030919 |
| Glaucoma, Primary Open Angle, Inflammation, Humor | Altered Intercellular Communication | The aqueous humor Hep level may exist locally and independent from the IL6 increase in patients with POAG, suggesting that Hep might represent a bridge protein between local inflammation and the consequent loss of retinal ganglion cells. | 21031015 |
| Inflammation | Altered Intercellular Communication | It can therefore be concluded that both changes represent the mucosa's reaction to recurrent or chronic inflammation. | 21031334 |
| Inflammation, Cerebrovascular accident | Altered Intercellular Communication | The identified genes elucidate differences in inflammation between stroke subtypes. | 21031583 |
| Inflammation | Altered Intercellular Communication | Chronic inflammation in dialysis patients increases the production of cytokines such as TNF-a, IL-1b and IFN- IFN-g and there is evidence of a significant mortality rate in dialysis patients due to inflammation. | 21031623 |
| Inflammation, Cholangitis, Neoplasms | Altered Intercellular Communication | 1CTP level tended to be higher in patients with cholangitis compared to those with no inflammation or benign tumors (p = 0.065). | 21033212 |
| Inflammatory, Crohn Disease, Chronic disease, Ulcerative Colitis | Altered Intercellular Communication | Non specific inflammations of the intestine are the group of chronic disorders, such as ulcerative colitis and Crohn's disease and with episodic aggravation of inflammatory lesions, called active phase and non-active phase, called remission. | 21033410 |
| Intraocular inflammation | Altered Intercellular Communication | Regarding the primary efficacy variable, intraocular inflammation, no microbial events were recorded, but aqueous flare was significantly lower with Tobramycin/Dexamethasone at 1 week (P = 0.002). | 21034176 |
| Postoperative infection, Acute inflammation | Altered Intercellular Communication | Both the studied fixed combinations are safe and effective in controlling postoperative inflammation and preventing postoperative ocular infections. | 21034176 |
| Intraocular inflammation, Retinitis | Altered Intercellular Communication | Intraocular inflammation was completely quiescent until 1 year following the implant, when he developed retinitis. | 21034309 |
| Inflammatory abnormality of the eye | Altered Intercellular Communication | Ocular inflammation resolved with systemic and topical steroid. | 21034312 |
| Inflammation, Ischemic stroke | Altered Intercellular Communication | Systemic markers of inflammation are independently associated with S100B concentration: results of an observational study in subjects with acute ischaemic stroke. | 21034449 |
| Inflammation, Brain Injuries, physiopathological, Acute Cerebrovascular Accidents | Altered Intercellular Communication | Vascular dysfunction and brain inflammation are thought to contribute to the pathophysiology of cerebral injury in acute stroke. | 21034449 |
| Inflammation, Lesion of brain, Brain Injuries, physiopathological | Altered Intercellular Communication | However acute inflammation and vascular dysfunction may simply be markers of an acute phase response to cerebral injury, reflecting the size of the cerebral lesion. | 21034449 |
| Inflammation, Brain Injuries, Ischemic stroke, physiopathological | Altered Intercellular Communication | We aimed to determine if systemic markers of vascular dysfunction and inflammation are independently associated with concentrations of the astroglial protein S100B, a marker of brain injury, in participants with acute ischaemic stroke. | 21034449 |
| Inflammation, Ischemic, Ischemic stroke | Altered Intercellular Communication | The degree of systemic inflammation is associated with S100B concentration in acute ischaemic stroke, independent of the size of the ischaemic lesion. | 21034449 |
| Inflammation, Critical Illness | Altered Intercellular Communication | Likewise, the neutrophil-lymphocyte count ratio (NLCR) has been shown a simple promising method to evaluate systemic inflammation in critically ill patients. | 21034463 |
| Inflammatory Bowel Diseases, Gastrointestinal inflammation | Altered Intercellular Communication | Inflammatory bowel disease (IBD) is characterized by chronic inflammation of the gastrointestinal tract. | 21035384 |
| Inflammatory Bowel Diseases, Inflammatory disease of mucous membrane | Altered Intercellular Communication | EBV replication was associated with severe IBD and mucosal inflammation. | 21035384 |
| Communicable Diseases, Inflammation | Altered Intercellular Communication | Increased proliferation and EBV infection of B-lymphocytes in inflamed colonic mucosa highlight the potential role of EBV in mucosal inflammation. | 21035384 |
| Inflammatory Bowel Diseases, Inflammation | Altered Intercellular Communication | The immunomodulatory effects of EBV could delay the resolution of the IBD associated inflammation, thus contributing to disease progression. | 21035384 |
| Inflammation, RPS6KA2 protein, human | Altered Intercellular Communication | RPS6KA1, RPS6KA2, RPS6KB1, RPS6KB2, and PDK1 are involved in several pathways central to the carcinogenic process, including regulation of cell growth, insulin, and inflammation. | 21035469 |
| Eosinophilic disorder, Inflammation, Hypereosinophilic syndrome | Altered Intercellular Communication | Hypereosinophilic syndromes (HES) are a heterogeneous group of conditions that are characterized by tissue-associated eosinophilic inflammation and peripheral eosinophilia. | 21036585 |
| ARCN1 gene, Inflammation, Chronic Obstructive Airway Disease | Altered Intercellular Communication | Chronic obstructive pulmonary disease (COPD) is characterized by progressive inflammation in the airways and lungs combined with disturbed homeostatic functions of pulmonary cells. | 21037022 |
| Inflammation, Unipolar Depression | Altered Intercellular Communication | We aimed to determine whether subclinical systemic inflammation, as measured by serum high-sensitivity C-reactive protein (hsCRP) concentration, is associated with an increased risk of de novo major depressive disorder. | 21037214 |
| Airway structure, ARCN1 gene | Altered Intercellular Communication | Assessment of airway inflammation using sputum, BAL, and endobronchial biopsies in current and ex-smokers with established COPD. | 21037956 |
| ARCN1 gene, Airway structure | Altered Intercellular Communication | However, there is little known in COPD about the detailed interrelationships between lung function and inflammatory profiles in different airway compartments from the same individual and whether airway inflammation in these different compartments differs in ex- and current smokers with established COPD. | 21037956 |
| Airway structure, ARCN1 gene | Altered Intercellular Communication | Airway inflammation persists in ex-smokers with COPD, but differs from COPD current smokers. | 21037956 |
| Inflammation, Autoimmune Chronic Hepatitis, Liver Cirrhosis | Altered Intercellular Communication | Autoimmune hepatitis is characterized by hepatocellular inflammation often progressing to cirrhosis. | 21037986 |
| Inflammation, Asthma | Altered Intercellular Communication | Phlegm, which is considered by Chinese medicine as an inveterate root of asthma, might be closely related with the inflammation in modern medicine. | 21038651 |
| Airway structure, Asthma | Altered Intercellular Communication | High serum arginase I levels in asthmatic patients may be associated with airway inflammation in non-atopic asthma. | 21039185 |
| Inflammation, Nasal Polyps, Chronic sinusitis | Altered Intercellular Communication | Fungi and/or Staphylococcus aureus enterotoxins (SEs) may participate in the pathogenesis of eosinophilic inflammation in cases of chronic rhinosinusitis with nasal polyps (CRSwNP). | 21039976 |
| Inflammation, Lung Diseases, Interstitial, Fibrosis Assessment, Hyperplasia | Altered Intercellular Communication | Idiopathic interstitial lung diseases (iILDs) are characterized by inflammation, hyperplasia of Type-II alveolar epithelial cells (AECs) and lung remodelling often with progressive fibrosis. | 21039988 |
| Inflammation | Altered Intercellular Communication | Lower serum high-density lipoprotein cholesterol (HDL-C) is associated with inflammation, insulin resistance and poor cardiovascular outcomes in the general population. | 21040164 |
| Inflammation, Osteopenia | Altered Intercellular Communication | In addition, no correlation was found between the fluid levels of molecules promoting inflammation and osteoclastic activity and the extent of bone loss in the hip (in terms of Saleh's classification) or the knee (AORI classification). | 21040654 |
| Inflammation, Family history, Atherosclerosis | Altered Intercellular Communication | We hypothesized that children with FH, as a model of early atherosclerosis, have different serum levels of inflammation markers than healthy control children. | 21040915 |
| Inflammation, Coronary Artery Disease | Altered Intercellular Communication | Pericardial fat inflammation correlates with coronary artery disease. | 21040916 |
| Inflammation, Coronary Artery Disease | Altered Intercellular Communication | We sought to assess the association between inflammation in pericardial fat (PF) and coronary artery disease (CAD) by pathological examination and clinical evaluation with cardiac computed tomography (CT). | 21040916 |
| Acute Coronary Syndrome, Inflammation | Altered Intercellular Communication | The CT density of PF around culprit lesions was significantly higher than non-culprit lesions in patients with acute coronary syndromes (-72 +- 11 vs. -82 +- 14 HU, p=0.002), which may reflect PF inflammation. | 21040916 |
| Inflammation, Hypertension, CTCAE, Dyslipidemias, Diabetes Mellitus | Altered Intercellular Communication | Multiple logistic regression analysis demonstrated that the PF inflammation index (PFI; PDG x PF volume, which could be the integrated index of inflammatory activity and abundance of PF) was significantly associated with the presence of CAD (odds ratio [95% confidence interval]; 1.234 [1.012-1.503] per 1000 HU cm(3), p=0.037) independent of other metabolic risk factors such as hypertension, dyslipidemia, and diabetes. | 21040916 |
| Inflammation | Altered Intercellular Communication | PF inflammation may be involved in pathogenesis of CAD. | 21040916 |
| Inflammation, Endothelial dysfunction | Altered Intercellular Communication | Attenuation by adipose tissue-associated inflammation, endothelial dysfunction, and NEFA was more modest (20.7%, 13.1%, and 9.5%, respectively). | 21040936 |
| Inflammation, Non-alcoholic Fatty Liver Disease, Endothelial dysfunction, Metabolic Syndrome X | Altered Intercellular Communication | Insulin resistance constitutes a key pathophysiological mechanism in the association between the metabolic syndrome and NAFLD (measured as ALT), which may operate through adipose tissue-associated inflammation and endothelial dysfunction and to a lesser extent through NEFA, which may have an independent role in the development of NAFLD in subjects with the metabolic syndrome. | 21040936 |
| Inflammation, Rheumatoid Arthritis | Altered Intercellular Communication | Effect of atorvastatin on inflammation and modification of vascular risk factors in rheumatoid arthritis. | 21041278 |
| Inflammation, Refractory anemias, Rheumatoid Arthritis, Endothelial dysfunction, Arterial Stiffness | Altered Intercellular Communication | To investigate the effect of atorvastatin therapy on inflammation, disease activity, endothelial dysfunction, and arterial stiffness in patients with rheumatoid arthritis (RA). | 21041278 |
| Inflammation, hepcidin, Neoplasms | Altered Intercellular Communication | Parallel variations of plasma IL-6, C-reactive protein, and hepcidin concentrations, together with tumor immunohistochemistry, strongly suggested that IL-6 synthesized by the tumor caused both the inflammation and iron deficiency through enhancement of hepcidin production by the liver. | 21041280 |
| Inflammation, Tissue Adhesions | Altered Intercellular Communication | The etiology of these fistulae is uncertain, but is thought to be related to post surgical injury and inflammation leading to adhesions and neorevascularization. | 21041861 |
| vascular inflammations | Altered Intercellular Communication | Serum adipocytokine and vascular inflammation marker levels in Beta-thalassaemia major patients. | 21042009 |
| vascular inflammations, beta Thalassemia | Altered Intercellular Communication | We aimed to analyze the levels of these adipocytokines and determine any possible correlations with disease severity or vascular inflammation markers in beta-thalassaemia. | 21042009 |
| Inflammation, ETV3 wt Allele | Altered Intercellular Communication | A marker of low grade inflammation provides useful predictive ability beyond other simple predictors in a female population with MetS prevailing. | 21042044 |
| methyldopa, Inflammation | Altered Intercellular Communication | In addition to hemostasis, TF can initiate intracellular signaling and promote inflammation and angiogenesis, the key processes underlying the pathogenesis of age-related macular degeneration (AMD). | 21042291 |
| methyldopa, Inflammation, Blindness | Altered Intercellular Communication | AMD, the leading cause of irreversible blindness among the elderly, involves many genetic and environmental risk factors, including oxidative stress and inflammation. | 21042291 |
| Inflammation | Altered Intercellular Communication | Growth-regulated oncogene a (GROa) is a chemokine that plays a role not only in inflammation, but also in tumorigenesis. | 21042742 |
| Inflammation, Primary malignant neoplasm | Altered Intercellular Communication | Recent studies have demonstrated aberrant CpG island methylation (CIM) in chronic inflammation, aging and cancer. | 21042749 |
| Inflammation, Non-alcoholic Fatty Liver Disease, Fatty degeneration | Altered Intercellular Communication | The pathological role of visceral fat accumulation in steatosis, inflammation, and progression of nonalcoholic fatty liver disease. | 21042922 |
| Inflammation, Comorbidity | Altered Intercellular Communication | The basis of this relationship with survival is not known; however, systemic inflammation may reflect comorbidity. | 21042941 |
| Inflammation, Amyloidosis, Periodontal Diseases | Altered Intercellular Communication | Interaction between periodontal disease and systemic secondary amyloidosis: from inflammation to amyloidosis. | 21043797 |
| Inflammation, Periodontal Diseases | Altered Intercellular Communication | It has become increasingly clear in recent years that periodontal disease can cause a dramatic increase in the levels of markers of systemic inflammation, and that periodontal treatment can result in reduction in the levels of these markers. | 21043797 |
| Inflammation, Myocardial Reperfusion Injury | Altered Intercellular Communication | TLR4 has been shown to mediate inflammation in animal models of myocardial ischemia/reperfusion injury (MI/RI). | 21044745 |
| Inflammation, Atherosclerosis | Altered Intercellular Communication | Adipo-(cyto)kines are associated with insulin resistance, atherosclerosis and inflammation. | 21044750 |
| Inflammation, Specimen Source Codes - Abscess | Altered Intercellular Communication | But no evidence of aortic or leaflet vegetations suggesting for abscess was found, neither atheromatous or calcified plaques, nor signs of inflammation of the aortic wall were detected. | 21044971 |
| Inflammation, Perforation (observation), Tuberculosis, Malignant Childhood Neoplasm, Typhoid Fever | Altered Intercellular Communication | The most common cause of non-traumatic perforation of small intestine was typhoid (46.4%), followed by non-specific inflammation (39.2%), tuberculosis (12.8%) and malignant neoplasm (1.6%). | 21045358 |
| Proximal tubulopathy | Altered Intercellular Communication | Biopsies showed varying degrees of tubulointerstitial inflammation, viral inclusions and evidence of tubular damage. | 21045390 |
| Cytomegalovirus | Altered Intercellular Communication | Histological features of PVN involving the kidneys have considerable morphological overlap with acute rejection while CMV disease presents primarily as tubulointerstitial inflammation. | 21045390 |
| Inflammation, Fibrosis Assessment, Fatty degeneration | Altered Intercellular Communication | All biopsies were evaluated for fibrosis, inflammation, and steatosis. | 21046172 |
| Hepatic inflammation, Hepatitis C | Altered Intercellular Communication | Metabolic factors, as well as sex and hepatic inflammation, are independent risk factors for serum ALT elevation in hepatitis C virus (HCV)-infected patients. | 21046172 |
| Sea Level Rise | Altered Intercellular Communication | The CEA-level, however, was within normal range and there was no evidence of hormonal overproduction. | 21046476 |
| Inflammation, VWF wt Allele | Altered Intercellular Communication | VWD is caused by a defect or deficiency in von Willebrand factor (VWF), a glycoprotein essential for normal hemostasis that is involved in inflammation. | 21048155 |
| Inflammation, destruction joint | Altered Intercellular Communication | Because mechanism for inhibition of inflammation or joint destruction might be independent, we should investigate further the relationship between inflammation and joint destruction in the future. | 21048388 |
| Inflammation, Coronary Artery Disease, Inflammatory disorder, Atherosclerosis | Altered Intercellular Communication | Since atherosclerosis may in part be an inflammatory disease, circulatory factors related to inflammation may be predictors of coronary artery disease. | 21048807 |
| Autoimmune Chronic Hepatitis, Insemination, Artificial, Homologous | Altered Intercellular Communication | Autoimmune hepatitis (AIH) is a chronic inflammatory condition of the liver of unknown etiology. | 21049414 |
| Intestinal metaplasia, Inflammation, Gland, Infection caused by Helicobacter pylori | Altered Intercellular Communication | Receiver operating characteristic (ROC) curve analysis showed that the sensitivity and specificity of CLE were 82.9% and 90.9% for the diagnosis of H. pylori infection, 94.6% and 97.4% for predicting gastric normal mucosa, 98.5% and 94.6% for predicting histological active inflammation, 92.9% and 95.2% for predicting glandular atrophy, 98.6% and 100% for diagnosing intestinal metaplasia, respectively. | 21049554 |
| Inflammation, Infestation, Demodex Mite | Altered Intercellular Communication | Infestation of Demodex mites induces change of tear cytokine levels, IL-17 especially, which cause inflammation of the lid margin and ocular surface. | 21050771 |
| Stomatitis, Atrophy of corpus callosum | Altered Intercellular Communication | The presence of dupA was also associated with an increased degree of antral mucosa inflammation (p=0.01) and with decreased corpus atrophy (p<0.01) as well as with increased gastric mucosa IL-8 levels (p=0.04). | 21050811 |
| Airway structure, Asthma | Altered Intercellular Communication | However, no biomarker of airways inflammation has been included in the assessment of asthma control. | 21051211 |
| Inflammation, Postoperative infection | Altered Intercellular Communication | During the surgical procedure, primary implant placement was successfully completed, and any postoperative infection or inflammation rapidly resolved in all 27 patients (29 eyes). | 21052507 |
| Communicable Diseases, Endophthalmitis, CTCAE, Inflammation | Altered Intercellular Communication | Evisceration with primary porous implant placement as the treatment for recalcitrant endophthalmitis resulted in rapid resolution of any infection and inflammation. | 21052507 |
| Inflammation, Traumatic injury | Altered Intercellular Communication | A previously healthy 50-year-old man was transferred to our hospital for evaluation of acute inflammation in his right eye after ocular trauma while using a grass mower. | 21052515 |
| Inflammation, Restenosis | Altered Intercellular Communication | Inflammation may play a pivotal role in LASM just as it plays in stent restenosis. | 21052690 |
| Intraocular inflammation, Sarcoidosis, Uveitis | Altered Intercellular Communication | Ninety-seven sarcoidosis patients with intraocular inflammation diagnosed at the Uveitis Clinic of Tokyo Medical University Hospital between 1997 and 2006 were analyzed retrospectively. | 21052899 |
| Aphthous Stomatitis, Intestines, Chronic inflammation | Altered Intercellular Communication | Biopsy of the intestinal lesions revealed chronic inflammation, aphthous ulcers and microgranulomas, favoring a diagnosis of CD. | 21053593 |
| Irritation - emotion, Inflammation | Altered Intercellular Communication | Microleakage can cause pulpal irritation and periapical inflammation. | 21053643 |
| Inflammation, Ulcerative Colitis | Altered Intercellular Communication | An adequate range of colonic observations for precise evaluation of inflammation in ulcerative colitis (UC) patients has not been reported. | 21054518 |
| Inflammation | Altered Intercellular Communication | The colonic site with maximum inflammation was determined for each patient. | 21054518 |
| Inflammation | Altered Intercellular Communication | Of 545 patients, 319 (59%) had maximum inflammation in the rectum, 79 (14%) in the sigmoid colon, 70 (13%) in the descending colon, and 77 (14%) on the oral side of the splenic flexure. | 21054518 |
| Inflammation | Altered Intercellular Communication | Moreover, among 134 patients with no inflammation in the rectum and sigmoid colon, 54 (40%) had inflamed mucosa in the descending colon or the more proximal portion. | 21054518 |
| Inflammation, Ulcerative Colitis | Altered Intercellular Communication | Sigmoidoscopy is not sufficient for evaluating inflammation in UC patients. | 21054518 |
| Inflammation, Cardiac complication, Chronic Kidney Diseases | Altered Intercellular Communication | Low-grade systemic inflammation, oxidative stress and peripheral insulin resistance are intimately associated and contribute to the increased risk of cardiovascular complications in advanced chronic kidney disease (CKD). | 21054584 |
| Albuminuria | Altered Intercellular Communication | Inflammation gene variants and susceptibility to albuminuria in the U.S. population: analysis in the Third National Health and Nutrition Examination Survey (NHANES III), 1991-1994. | 21054877 |
| Inflammation | Altered Intercellular Communication | While the underlying etiology is unclear, chronic, low-grade inflammation is a suspected key factor. | 21054877 |
| Albuminuria | Altered Intercellular Communication | Our findings suggest a small role for genetic variation within inflammation-related genes to the susceptibility to albuminuria. | 21054877 |
| Inflammation, Kidney damage | Altered Intercellular Communication | Additional studies are needed to further assess whether genetic variation in these, and untested, inflammation genes alter the susceptibility to kidney damage. | 21054877 |
| Inflammation, Peripheral T-Cell Lymphoma, B-Cell Lymphomas | Altered Intercellular Communication | The control cases included 18 cases of peripheral T-cell lymphoma, 10 cases of B-cell lymphoma, 5 cases of normal spleen, 5 cases of normal thymus and 10 cases of nasal mucosal tissues affected by chronic inflammation. | 21055151 |
| Granulomatous inflammation | Altered Intercellular Communication | The diagnosis was supported by detection of granulomatous inflammation in a laryngeal biopsy. | 21055382 |
| Inflammation, Neoplasms, Nephrolithiasis | Altered Intercellular Communication | Chronic inflammation and renal lithiasis seem to be associated with this tumour. | 21055527 |
| Inflammation, Fibrosis Assessment, Primary malignant neoplasm | Altered Intercellular Communication | Circulating levels of YKL-40 are related to the degree of inflammation, tissue remodeling, fibrosis, and cancer progression. | 21055651 |
| Inflammation, Congestive heart failure | Altered Intercellular Communication | Serum YKL-40, a new marker of inflammation, was increased in CHF, and YKL-40 detected high risk patients for adverse outcomes in CHF. | 21055651 |
| Inflammation, Peri-Implantitis | Altered Intercellular Communication | We concluded that in the presence of peri-implant inflammation, bone quantity and characteristics may influence the progression of peri-implantitis bone loss at dental implants. | 21055752 |
| Inflammation, Peri-Implantitis | Altered Intercellular Communication | To achieve an understanding of the local degradation of bone due to peri-implantitis, we need to analyze the microstructure of the bone as well the cellular biology of the peri-implant inflammation. | 21055752 |
| Refractory anemias, Inflammation | Altered Intercellular Communication | SF Th1 percentages directly correlated with inflammation and disease activity (CRP, swollen joint count [SJC]) indices in SpA, but not in RA patients. | 21056009 |
| Inflammation, Esthesia, Swelling, Back Pain, Arthritis | Altered Intercellular Communication | Self-reported arthritis-related illness was indicated by the presence of arthritis, back and joint pain, biting sensation, swelling and inflammation in the joints. | 21056439 |
| Delirium | Altered Intercellular Communication | Impaired cholinergic neurotransmission seems to have an important role in the development of delirium. | 21056464 |
| Inflammation, Hypertrophy | Altered Intercellular Communication | Mice deficient in MMP-9 develop the same degree of cigarette smoke-induced inflammation and airspace enlargement as strain-matched controls. | 21057003 |
| Inflammatory Bowel Diseases | Altered Intercellular Communication | Inflammatory bowel disease (IBD) is a group of inflammatory conditions of the gastrointestinal tract. | 21057150 |
| Inflammation, Communicable Diseases, Fibrosis Assessment, Bipolar Disorder, Fatigue | Altered Intercellular Communication | Clinical parameters including infection activity, fibrosis stage or inflammation grade, as well as depressive symptoms and fatigue were found to be significantly associated with HRQOL. | 21057161 |
| Inflammatory abnormality of the eye | Altered Intercellular Communication | The ocular inflammation subsided gradually and her BCVA returned to normal after intensive steroid treatment. | 21057804 |
| Metabolic Diseases, Atherosclerosis | Altered Intercellular Communication | Osteocalcin, a bone-derived polypeptide, was recently found to have hormonal function associated with metabolic disorders and atherosclerosis. | 21059437 |
| Cerebrovascular, Inflammation, Atherosclerosis | Altered Intercellular Communication | Inflammation plays a pivotal role in the pathogenesis of atherosclerosis and of cerebrovascular complications. | 21059542 |
| Inflammation | Altered Intercellular Communication | Transforming growth factor-b (TGF-b) is a pleiotropic cytokine with a central role in inflammation. | 21059542 |
| Inflammation, Seizures, Encephalitis, Hallucinations, Agitation, Irritable Mood, Thinking, function, Psychiatric, Bacterial Infections | Altered Intercellular Communication | These included encephalitic signs with psychiatric symptoms (agitation, paranoid thoughts, irritability, or hallucinations); seizures; CSF inflammation; and exclusion of viral or bacterial infection. | 21060097 |
| Intraocular inflammation | Altered Intercellular Communication | Two patients developed intraocular inflammation with high intraocular pressure 3 and 5 weeks after the infliximab injection, respectively. | 21060271 |
| Intraocular inflammation | Altered Intercellular Communication | In addition, half of the cases developed intraocular inflammation. | 21060271 |
| Inflammation, Obesity | Altered Intercellular Communication | Age, sex, and ethnicity may modify the influence of obesity on inflammation. | 21060285 |
| Inflammation, Obesity | Altered Intercellular Communication | Many medical concerns associated with obesity are due to chronic inflammation, but factors underlying the development or maintenance of obesity-associated inflammation remain unclear. | 21060285 |
| Inflammation, Obesity | Altered Intercellular Communication | This study investigated how age, sex, and ethnicity may modify the interplay of subclinical inflammation and obesity in nationally representative contexts. | 21060285 |
| Inflammation, Obesity | Altered Intercellular Communication | Factors, such as age, sex, and ethnicity, may modify the influence of obesity on subclinical inflammation at the population level. | 21060285 |
| Optic Neuritis | Altered Intercellular Communication | TGF-b1 induces an age-dependent inflammation of nerve ganglia and fibroplasia in the prostate gland stroma of a novel transgenic mouse. | 21060787 |
| Prostate carcinoma | Altered Intercellular Communication | The novel findings of ganglia and vessel inflammation associated with formation of collagenous micronodules in collapsed acini is important as each of these are observed in human prostate carcinoma and may play a role in disease progression. | 21060787 |
| Inflammation, Hodgkin Disease | Altered Intercellular Communication | Hodgkin disease risk: role of genetic polymorphisms and gene-gene interactions in inflammation pathway genes. | 21061265 |
| Inflammation, Primary malignant neoplasm | Altered Intercellular Communication | Inflammation is a critical component of cancer development. | 21061265 |
| HD Term Type, Inflammation | Altered Intercellular Communication | Our study is the first to report the association between polymorphisms in inflammation genes and HD susceptibility risk. | 21061265 |
| Inflammation, Atherosclerosis | Altered Intercellular Communication | Invariant natural killer T cells: linking inflammation and neovascularization in human atherosclerosis. | 21061446 |
| Rupture | Altered Intercellular Communication | Inflammation participates in lesion progression and plaque rupture. | 21061446 |
| Watery diarrhea, Fever, CTCAE | Altered Intercellular Communication | A 73-year-old Japanese male was admitted because of difficulty in standing up after acute upper respiratory inflammation with mild fever followed by watery diarrhea. | 21061550 |
| Inflammation, Fibrosis Assessment, Myocarditis, CTCAE 5.0, Ischemia | Altered Intercellular Communication | Conversely, fat replacement without fibrosis may be seen secondary to infectious myocarditis, chronic inflammation, and ischemia and as part of the aging process. | 21062175 |
| Pain Distress Question, Inflammation | Altered Intercellular Communication | Salicylates have been used since antiquity to relieve pain and inflammation. | 21062358 |
| Amyotrophic Lateral Sclerosis, Neurodegenerative Disorders, Inflammation | Altered Intercellular Communication | The contribution of inflammation to neurodegenerative diseases is increasingly recognized, but the role of inflammation in sporadic amyotrophic lateral sclerosis (sALS) is not well understood and no animal model is available. | 21062492 |
| Inflammation | Altered Intercellular Communication | Aggregated wild type SOD-1 in sALS neurons could induce in mononuclear cells the cytokines inducing chronic inflammation in sALS spinal cord, in particular IL-6 and IL-17A, damaging neurons. | 21062492 |
| Inflammation | Altered Intercellular Communication | Immune modulation of chronic inflammation may be a new approach to sALS. | 21062492 |
| Carcinoma of lung | Altered Intercellular Communication | Hormonal and EGFR pathways together may contribute to lung cancer prognosis. | 21062926 |
| Acute Coronary Syndrome, vascular inflammations, Dental Plaque, GDC AJCC Clinical Stage Terminology | Altered Intercellular Communication | Vascular inflammation can lead to plaque instability and acute coronary syndromes (ACS). | 21062996 |
| Inflammation, Coronary Artery Disease | Altered Intercellular Communication | We are led to conclude that inflammation that occurs locally in epicardial adipose tissue of CAD contributes to the pathogenesis of coronary artery disease. | 21063839 |
| Inflammation, Hepatitis B | Altered Intercellular Communication | Hepatitis B is inflammation of the liver caused by a Hepatitis B virus, having a parenteral mode of entry and infecting millions of people around the world. | 21067032 |
| Seroma, Fibrosis Assessment, Inflammation, Neoplasms | Altered Intercellular Communication | DCE-MRI differentiated the rapidly enhancing recurrences, residual tumors and metastases from the slowly enhancing inflammation, and the non-enhancing seromas and fibrosis. | 21067882 |
| Communicable Diseases, Fracture, Osteoporosis, Myositis | Altered Intercellular Communication | RadRx further predisposed post-resection and post-ECRRI patients to develop fractures, osteoporosis and infection and was the major cause of persistent muscle inflammation at MRI. | 21067882 |
| Inflammation, Rheumatoid Factor, Synovitis | Altered Intercellular Communication | On an individual level, USGS inflammation, MRI synovitis and MRI BME also somewhat better predicted outcome than rheumatoid factor, anticitrullinated protein antibodies and disease activity score 28. | 21068093 |
| Refractory anemias, Inflammation | Altered Intercellular Communication | USGS inflammation and MRI BME were independent predictors of MRI erosive progression in early RA patients on a group level. | 21068093 |
| Inflammation | Altered Intercellular Communication | Greater variety in fruit and vegetable intake is associated with lower inflammation in Puerto Rican adults. | 21068354 |
| Inflammation | Altered Intercellular Communication | FV variety, but not quantity, appears to be important in reducing inflammation. | 21068354 |
| Inflammation, Epstein-Barr Virus Infections, Neurologic Symptoms | Altered Intercellular Communication | Primary EBV infections in immune competent persons can cause a broad range of neurological symptoms, with lymphocytic and monocytic inflammation both in blood and CSF. | 21070089 |
| Communicable Diseases, Inflammation | Altered Intercellular Communication | Among 16 patients presenting with preerosion associated with signs of local cutaneous inflammation, 62.5% developed an infection of the pacing system requiring later explantation. | 21070257 |
| Inflammation | Altered Intercellular Communication | Extensive, previous evidence (reviewed here) indicates an important role for noradrenaline in the control of inflammation in the brain. | 21070631 |
| Inflammation, Data types - Address | Altered Intercellular Communication | Thus, the -1021T allele with presumed low activity may be associated with misregulation of inflammation, which could contribute to the onset of AD. | 21070631 |
| Inflammation, Dysphonia, Posterior rhinorrhea | Altered Intercellular Communication | The common findings of the upper respiratory tract were dysphonia (79.1%), post-nasal discharge (PND; 41.9%), lower larynx position (30.2%), limitation of vocal cords (25.6%) and mucosal inflammation of larynx (14.8%). | 21071549 |
| Inflammation, Restenosis, Atherosclerosis | Altered Intercellular Communication | Resistin is an adipocytokine that may link inflammation and atherosclerosis.We studied the associations of resistin levels with cardiovascular events and restenosis. | 21071880 |
| Inflammation | Altered Intercellular Communication | Grade of inflammation was rated according to the updated Sydney Scoring System. | 21073375 |
| Inflammation, Gastritis | Altered Intercellular Communication | Gastritis was classified as corpus-predominant when the degree of chronic inflammation was higher in the corpus than in the antrum and vice versa for antrum-predominant gastritis. | 21073375 |
| Inflammation, Dental Plaque | Altered Intercellular Communication | In addition FABP4/aP2 correlates with other important signs of inflammation and plaque instability, such as T cells and leukotriene enzymes. | 21073559 |
| Inflammation | Altered Intercellular Communication | Taken together, these results indicate that FABP4/aP2 is a key factor connecting vascular and cellular lipid accumulation to inflammation. | 21073559 |
| Inflammation | Altered Intercellular Communication | In patients with a DU, moderate-severe chronic inflammation at the lesser and greater curvatures of corpus was associated with GC risk (OR, 3.70; 95% CI, 1.46-9.36, and OR, 7.72; 95% CI, 3.18-18.7, respectively). | 21073608 |
| Inflammation, PDR gene | Altered Intercellular Communication | Further studies are needed to provide better understanding of IL-8 and inflammation involvement in visual prognosis in PDR. | 21073666 |
| Intraocular inflammation, Lesion of retina | Altered Intercellular Communication | In 15 eyes (75%) the retinal lesions were associated with intraocular inflammation. | 21074095 |
| Inflammation, Fracture | Altered Intercellular Communication | The abundance of a selection of transcript species involved in inflammation, immunosenescence and stress response was compared between PBMC of 35 geriatric patients with hip fracture in acute phase (days 2-4 after hospitalization) or convalescence phase (days 7-10) and 28 healthy aged controls. | 21074600 |
| Inflammation, Fibrosis Assessment, Abnormally opaque structure (morphologic abnormality) | Altered Intercellular Communication | Lung computed tomography showed diffuse centrilobular nodules and branching linear opacities, whereas lung biopsy demonstrated diffuse peribronchiolar fibrosis and chronic inflammation with bronchiolectasis. | 21074694 |
| ARCN1 gene, Inflammation, Chronic Obstructive Airway Disease | Altered Intercellular Communication | C-reactive protein (CRP) and erythrocyte sedimentation rate (ESR) as inflammation markers in elderly patients with stable chronic obstructive pulmonary disease (COPD). | 21074870 |
| ARCN1 gene, Inflammation, Chronic Obstructive Airway Disease | Altered Intercellular Communication | Erythrocyte sedimentation rate (ESR) might represent a less expensive alternative to C-reactive protein (CRP) as a marker of systemic inflammation in stable chronic obstructive pulmonary disease (COPD). | 21074870 |
| Gastrointestinal inflammation, Colitis | Altered Intercellular Communication | Thirty-three patients (7.1%) reported serious AEs; one patient's severe gastrointestinal inflammation and colitis were considered possibly study drug-related. | 21075272 |
| Hemorrhagic Fevers, Viral, Acute inflammation, Hemorrhagic Fever with Renal Syndrome, Syndrome | Altered Intercellular Communication | This report describes a rare clinical manifestation of hemorrhagic fever with renal syndrome (HFRS), and shows that HFRS might be difficult to diagnose especially when symptoms mimick those of an acute abdominal inflammation. | 21075678 |
| Inflammation | Altered Intercellular Communication | The greatest impact on this result had early adverse events as insufficient closure, wound incrustation, and inflammation (9.3 vs. 6.0%; P = 0.02). | 21075757 |
| Inflammation, Heart failure | Altered Intercellular Communication | Cardiac inflammation contributes to changes in the extracellular matrix in patients with heart failure and normal ejection fraction. | 21075869 |
| Inflammation | Altered Intercellular Communication | Here we report the influence of cardiac inflammation on extracellular matrix (ECM) remodeling in patients with HFNEF. | 21075869 |
| Diastolic dysfunction, Inflammation, Fibrosis Assessment | Altered Intercellular Communication | A positive correlation between cardiac collagen, as well as the amount of inflammatory cells, and diastolic dysfunction was evident and suggests a direct influence of inflammation on fibrosis triggering diastolic dysfunction. | 21075869 |
| Diastolic dysfunction, Inflammation | Altered Intercellular Communication | Cardiac inflammation contributes to diastolic dysfunction in HFNEF by triggering the accumulation of ECM. | 21075869 |
| Inflammation | Altered Intercellular Communication | Epitope 4 includes the interaction site between sEPCR and PR3 which may serve as an important interaction to down-regulate inflammation. | 21077276 |
| Communicable Diseases, Inflammation | Altered Intercellular Communication | Nevertheless the disease may recur in the inguinal areas and frequently be lethal, therefore close surveillance and early attempts to treat the recurrent disease before infection and inflammation ensues should be the aim of current treatment strategies. | 21077489 |
| Refractory anemias, Rheumatoid Arthritis, Inflammation, Physical disability | Altered Intercellular Communication | To determine whether low-dose prednisolone affects body composition and bone mineral density (BMD) in patients with rheumatoid arthritis (RA), also considering inflammation and physical disability. | 21077801 |
| Refractory anemias, Inflammation, Federated States of Micronesia | Altered Intercellular Communication | RA patients treated with low-dose prednisolone had significantly higher FM than patients without prednisolone, an effect that was independent of current inflammation. | 21077801 |
| Gastrointestinal inflammation | Altered Intercellular Communication | Selective inhibition of IFN-g mediated apoptosis, while preserving its beneficial consequences on the ratio of IL-18/IL-18bp, could contribute to the integrity of the mucosal barrier in intestinal inflammation. | 21078084 |
| Inflammation, Crohn Disease | Altered Intercellular Communication | Low-dose (18)F-FDG PET/CTE, compared with CTE, may improve the detection and grading of active inflammation in patients with Crohn disease. | 21078803 |
| Orosomucoid, Inflammation, Buccal Route of Drug Administration | Altered Intercellular Communication | Bone loss was observed buccally and was more pronounced in patients with GAgP, with a significant correlation with keratinized mucosa and increased inflammation. | 21080785 |
| Inflammation, Primary malignant neoplasm | Altered Intercellular Communication | There is growing evidence that inflammation is a causal factor in cancer, where pro-inflammatory cytokines such as IL-6, IL-1 or TNF-a could induce cellular proliferation by activation of NF-kB. | 21081304 |
| Colorectal Carcinoma, Obesity | Altered Intercellular Communication | Our study supports the concept that obesity-related inflammation, rather than obesity itself, is associated with colorectal cancer progression and survival. | 21081932 |
| Inflammation, Liver damage | Altered Intercellular Communication | Two of the upregulated genes, LCN2 and IQGAP1, have been previously linked to inflammation in smokers and response/repair to cellular injury in bronchial epithelium. | 21082746 |
| Presenile dementia, Inflammation | Altered Intercellular Communication | Few cross-sectional studies and some longitudinal studies have attempted to link oral health with dementia diagnosis or disease pathology but none has investigated the role of inflammation as a potential mediator. | 21083740 |
| Inflammation, Hemorrhage, Dental Plaque | Altered Intercellular Communication | After adjusting for age, significant differences were found between patients and controls with respect to gingival inflammation, dental plaque, bleeding on probing and probing pocket depth. | 21083740 |
| Inflammation, Meibomian gland dysfunction | Altered Intercellular Communication | Bacteria and chronic inflammation are contributing factors for meibomian gland disease, which leads to ocular surface and tear film alterations and chronic patient symptoms. | 21083761 |
| Inflammation | Altered Intercellular Communication | The often chronic inflammation and immune activation status in dialysis patients may accelerate tryptophan degradation, which could influence patients' psychological performance. | 21084050 |
| Inflammation, Acute myocardial infarction, Anemia | Altered Intercellular Communication | The development of anemia of inflammation during acute myocardial infarction. | 21084124 |
| Inflammation, Anemia | Altered Intercellular Communication | A pattern suggestive of anemia of inflammation including higher ferritin, lower transferring, lower transferrin saturation, and lower serum iron concentrations has been observed in anemic AMI patients ( all p<0.05). | 21084124 |
| Inflammation, Anemia | Altered Intercellular Communication | We therefore suggest the possibility that at least part of the hemoglobin drop in AMI prior to angiography is related to the anemia of inflammation. | 21084124 |
| Appendicitis, CTCAE, Intraluminal Route of Drug Administration | Altered Intercellular Communication | Computed tomography criterion for the diagnosis of appendicitis without periappendiceal inflammation in children using the maximum depth of intraluminal appendiceal fluid. | 21084908 |
| Appendicitis, CTCAE | Altered Intercellular Communication | Of 826, 192 were classified into the noncomplicated-normal appendix group (85 enlarged normal appendices [diameter >6 mm] without adjacent lesions), the complicated-normal appendix group (44 enlarged normal appendices with adjacent lesions), or the our-appendicitis group (63 operatively proved appendicitis without periappendiceal inflammation). | 21084908 |
| Appendicitis, CTCAE | Altered Intercellular Communication | The criterion "DEPTH greater than 2.6 mm" is particularly useful for differentiating appendicitis without periappendiceal inflammation from enlarged normal appendices in children. | 21084908 |
| Inflammation, Breast Carcinoma | Altered Intercellular Communication | Regular exercise has been shown to protect against breast cancer risk, and one possible mechanism is through a reduction in inflammation. | 21085036 |
| Sepsis, Inflammation, Acute Lung Injury | Altered Intercellular Communication | Our data demonstrate the critical role of early-age-related proteostasis-imbalance as a novel mechanism that augments the NFkB mediated inflammation in sepsis and ALI. | 21085581 |
| Inflammation | Altered Intercellular Communication | Moreover, our data suggest the therapeutic efficacy of salubrinal in restraining NFkB mediated inflammation in the adult or older subjects. | 21085581 |
| Inflammation, Adenoma of lung, Interstitial Fibrosis Assessment, Idiopathic Pulmonary Fibrosis | Altered Intercellular Communication | Thus, lung tissue remodeling in the progression of IPF from the early to late stage of the disease comprises interrelated processes that are largely localized in the BATZ, such as immune inflammation with pathological reparation, neoangiogenesis, apoptosis, and proliferation of epitheliocytes and myofibroblasts, which lead to the development of interstitial fibrosis and adenomatosis of the lung. | 21086635 |
| Inflammation, Pancreatitis, Organ Dysfunction Scores, Infection, Cessation of life | Altered Intercellular Communication | Severe acute pancreatitis is associated with systemic inflammation, compensatory immune suppression, secondary infections, vital organ dysfunction, and death.Our study purpose was to delineate signaling profiles of circulating lymphocytes in acute pancreatitis complicated by organ dysfunction. | 21087472 |
| Pancreatitis, Acute, Inflammation, Organ Dysfunction Scores, Increase, IMMUNE SUPPRESSION | Altered Intercellular Communication | Lymphocytes of patients with acute pancreatitis, organ dysfunction and immune suppression show impaired NFkB activation, which increases infection risk and enhanced p38 activation, which sustains inflammation. | 21087472 |
| Airway structure, Inflammation, Respiratory Hypersensitivity | Altered Intercellular Communication | Common problems were: airways hyper-responsiveness (80%); airway inflammation (74%); activity limitation (74%) and systemic inflammation (60.5%). | 21087988 |
| Autoimmune Diseases, Inflammation, Neoplasms, Histopathologic Grade differentiation | Altered Intercellular Communication | B cells lacking the tumor suppressor TNFAIP3/A20 display impaired differentiation and hyperactivation and cause inflammation and autoimmunity in aged mice. | 21088135 |
| Inflammation | Altered Intercellular Communication | Accurate assessment is crucial because an intraoperative diagnosis of chronic inflammation suggestive of ALVAL will necessitate a replacement of the prosthetic component surfaces. | 21088151 |
| vascular inflammations | Altered Intercellular Communication | We thus hypothesized that treatment with atazanavir would ameliorate oxidative stress and vascular inflammation and improve endothelial function in T2DM. | 21088253 |
| Vascular Diseases, Fibrosis Assessment, Inflammation | Altered Intercellular Communication | Retroperitoneal fibrosis is an uncommon collagen vascular disease of unknown etiology, characterized by the replacement of normal retroperitoneal tissue with fibrosis and/or chronic inflammation usually surrounding the abdominal aorta and the iliac arteries and extending into adjacent anatomic structures. | 21088348 |
| Inflammation, Traumatic injury, Malignant Neoplasms, FAM126A gene, Liver Cirrhosis | Altered Intercellular Communication | Unlike most of the other malignancies, HCC almost entirely develops in the context of inflammation and organ injury and is related to cirrhosis in about 85% of the cases. | 21088408 |
| Nonalcoholic Steatohepatitis, Inflammation, Heart failure, Chronic Kidney Diseases | Altered Intercellular Communication | chronic renal disease, non-alcoholic steatohepatitis, heart failure or sclerosis) and malignant progression (and likely by reducing TGFb-regulated inflammation and immune responses -inflamm-aging-), molecularly behaves as a bona fide anti-aging modality. | 21088486 |
| Nonalcoholic Steatohepatitis, Inflammation, Heart failure, Chronic Kidney Diseases | Altered Intercellular Communication | chronic renal disease, non-alcoholic steatohepatitis, heart failure or sclerosis) and malignant progression (and likely by reducing TGFb-regulated inflammation and immune responses -inflamm-aging-), molecularly behaves as a bona fide anti-aging modality. | 21088486 |
| Inflammation, Acute Coronary Syndrome | Altered Intercellular Communication | The obtained data allows assuming the important role of the IL6 and IL10 genes which are responsible for functioning of inflammation system, in the accelerated formation of failures at the patients who had a coronary syndrome. | 21090240 |
| Trachoma , Inflammation, Tissue Factor | Altered Intercellular Communication | Only 3 children were identified with active trachoma (trachoma with follicles, TF = 1; trachoma with intense inflammation, TI = 2) giving regional prevalence of 0.01% (Confidence Limits, CL: 0.0-0.1) for TF and 0.03% (CL: 0.0-0.1) for TI. | 21090908 |
| Inflammation, Hypertensive Retinopathy | Altered Intercellular Communication | The association of low-grade systemic inflammation with hypertensive retinopathy. | 21091359 |
| Inflammation, Retinal Diseases | Altered Intercellular Communication | Elevated blood pressure (BP) alone does not fully account for the extent of retinopathy, other pathogenic mechanisms may be involved, such as low-grade inflammation. | 21091359 |
| Tissue damage, Inflammation, Pathology | Altered Intercellular Communication | Cardiopulmonary bypass (CPB) causes alterations in the levels of biomarkers related to inflammation, tissue damage, and other tissue pathologies. | 21092041 |
| Tissue damage, Inflammation | Altered Intercellular Communication | Early and accurate evaluation of inflammation and tissue damage would therefore be clinically useful. | 21092041 |
| Inflammation, Diabetes Mellitus, Cardiovascular Diseases | Altered Intercellular Communication | Compared with abstainers, alcohol consumption was associated with a decreased risk of having diabetes mellitus in women (OR: 0.41, 95%CI: 0.22-0.78) after controlling for socio-demographic factors, physical activity, smoking, family income, family history of cardiovascular disease or diabetes, macronutrients intake, body mass index, and markers of inflammation and adipokines. | 21092093 |
| Inflammation | Altered Intercellular Communication | For each case, systemic and local antibiotics did not control corneal thinning, which seemed correlated with the intensity of the systematically associated signs of scleral inflammation. | 21093102 |
| Inflammation, Malnutrition | Altered Intercellular Communication | Handgrip strength as a simple indicator of possible malnutrition and inflammation in men and women on maintenance hemodialysis. | 21093287 |
| Inflammation, Malnutrition | Altered Intercellular Communication | These results suggest that HGS is a valid screening instrument for malnutrition and inflammation in patients on MHD. | 21093287 |
| Old age, Inflammation | Altered Intercellular Communication | Angiotensin II (Ang II) promotes inflammation and the generation of reactive oxygen species and governs onset and progression of vascular senescence, which are all associated with functional and structural changes, contributing to age-related diseases. | 21093722 |
| Hypotension, Orthostatic, Gastrointestinal dysmotility, Anhidrosis | Altered Intercellular Communication | Autoantibodies that impair synaptic transmission in the autonomic ganglia may cause orthostatic hypotension, gastrointestinal dysmotility, and sudomotor dysfunction. | 21093734 |
| Gastrointestinal inflammation, Obesity | Altered Intercellular Communication | Based on animal studies, RELMb is induced by high fat diets, obesity, and intestinal microflora and may play a role in insulin resistance and intestinal inflammation. | 21094111 |
| Irritation - emotion, Inflammation | Altered Intercellular Communication | The etiology is still unknown; however, SP is considered a consequence of chronic irritation and inflammation. | 21094868 |
| Pyelonephritis, Nephritis | Altered Intercellular Communication | Xanthogranulomatous pyelonephritis is a chronic renal inflammation characterized by destruction and replacement of its parenchyma with granulomatous tissue. | 21094988 |
| Inflammation | Altered Intercellular Communication | Low-grade chronic inflammation is an important risk factor for age-related morbidity. | 21097658 |
| Inflammation | Altered Intercellular Communication | Health behaviors, including average aggregate measures of sleep, have been linked to increased inflammation in older adults. | 21097658 |
| Inflammation | Altered Intercellular Communication | Variability in sleep timing may also be associated with increased inflammation. | 21097658 |
| Inflammation, Thrombosis | Altered Intercellular Communication | The remaining patient showed glomerular inflammation and thrombosis, with diffuse C4d glomerular and peritubular capillary deposition, and hypermutated V region genes. | 21097789 |
| Inflammation | Altered Intercellular Communication | Systemic inflammation was not associated with erosive activity. | 21097802 |
| Inflammation, Acute myocardial infarction, "Alzheimers Disease", Data types - Address | Altered Intercellular Communication | Gene variants that promote inflammation and cholesterol metabolism have been associated with acute myocardial infarction (AMI) and Alzheimer's disease (AD). | 21098980 |
| Inflammation, Data types - Address | Altered Intercellular Communication | We conclude that AMI and AD share genetic backgrounds involving cholesterol metabolism and the upregulation of inflammation and that gene-gene interactions in relevant sets of genes may be useful in defining inherited risk for common disorders. | 21098980 |
| Airway structure, Asthma | Altered Intercellular Communication | Our data suggest that eNO level inversely correlates with small airway narrowing, and airway inflammation has a significant effect on small airway lung function in asthmatic school children. | 21099248 |
| Inflammation, Asthma | Altered Intercellular Communication | Saliva has recently been validated as novel, simple, and noninvasive method for investigating inflammation in patients with asthma. | 21099251 |
| Necrotizing granulomatous inflammation | Altered Intercellular Communication | Histopathologically, sections of the iridectomy specimen showed a zonal granulomatous inflammation with a central iris necrotic abscess surrounded by a mantle of epithelioid histiocytes and more peripherally by lymphocytes and plasma cells. | 21099401 |
| Fibrosis Assessment, Hypertrophy | Altered Intercellular Communication | Recent studies showed that fibrosis in LF hypertrophy was due to accumulation of inflammation-related scar tissue. | 21102276 |
| Inflammation | Altered Intercellular Communication | MRI can detect active inflammation and structural damage associated with SpA. | 21102381 |
| Communicable Diseases, Inflammation | Altered Intercellular Communication | We defined iron deficiency according to the presence of malarial infection and evidence of inflammation. | 21103365 |
| Muscle Contraction, Inflammation | Altered Intercellular Communication | The results suggest that SLT induces prominent increases in CBT and IT returning to baseline thickness in a month, which may be caused by inflammation, vascular engorgement, or mechanical muscular contraction. | 21104268 |
| Inflammation, Diabetes Mellitus, Non-Insulin-Dependent, Obesity | Altered Intercellular Communication | Obesity and insulin resistance are characterized by a chronic and low grade state of inflammation and the pro-inflammatory response of monocytes is affected in type 2 diabetes mellitus (T2D). | 21104588 |
| Cardiovascular Diseases, Atherosclerotic lesion, Atherosclerosis | Altered Intercellular Communication | We randomly selected 411 of 1268 participants with pre-existent cardiovascular disease from the prospective Inflammation in Carotid Arteries Risk for Arthrosclerosis Study (ICARAS) and assessed their OPGs for the presence of calcified atherosclerotic lesions or indirect signs of atherosclerosis, such as surgical clips or intravascular stents. | 21104618 |
| Inflammation, Muscle damage | Altered Intercellular Communication | Quality of life, inflammation, muscle damage and disease activity scores remained unchanged. | 21106107 |
| Orbital Pseudotumor, Diabetes Mellitus | Altered Intercellular Communication | Two male adults were admitted because of newly diagnosed diabetes with hyperglycemic hyperosmolar state and CT scan showed extensive pansinusitis and orbital inflammation. | 21106269 |
| Inflammation, Cardiac Arrhythmia, Ischemia | Altered Intercellular Communication | Cardiac risk factors, left ventricular ejection fraction (LVEF), medical therapy, inflammation status, and perioperative ischemia in relation to arrhythmia were noted in all patients. | 21106322 |
| Inflammation | Altered Intercellular Communication | Successful ablation of AF, with sinus rhythm restoration and maintenance, is associated with decreased serum levels of markers of inflammation. | 21106468 |
| Cessation of life, Inflammation, Primary malignant neoplasm, Cardiovascular Diseases | Altered Intercellular Communication | Simple indices of inflammation as predictors of death from cancer or cardiovascular disease in a prospective cohort after two decades of follow-up. | 21106505 |
| Inflammation, Primary malignant neoplasm, Cyclophosphamide/Vincristine/Dacarbazine Regimen, Cardiovascular Diseases | Altered Intercellular Communication | Previous studies have identified sub-clinical inflammation as a potential factor in the pathogenesis of cancer and cardiovascular disease (CVD) but the possibility that simple, readily measured indices of sub-clinical inflammation might predict both CVD and cancer has not been tested in the context of a single, prospective analysis. | 21106505 |
| Cessation of life, Inflammation, Primary malignant neoplasm | Altered Intercellular Communication | To evaluate simply measured indices of inflammation as long-term predictors of death from either cancer or CVD. | 21106505 |
| Inflammation, Primary malignant neoplasm | Altered Intercellular Communication | The inflammation score predicted both cancer mortality (1.35, P = 0.003) and CVD mortality (1.46, P = 0.002). | 21106505 |
| Inflammation, Primary malignant neoplasm, Cyclophosphamide/Vincristine/Dacarbazine Regimen | Altered Intercellular Communication | Risks associated with high inflammation score were equivalent to and independent of smoking cigarettes for cancer or, for CVD, having a serum cholesterol concentration >=6.2 mmol/l. | 21106505 |
| Cessation of life, Inflammation, Primary malignant neoplasm | Altered Intercellular Communication | Simple indices of inflammation predict death from cancer or CVD two decades later as strongly as smoking predicts cancer or cholesterol predicts CVD. | 21106505 |
| Inflammation, Diabetes Mellitus, Non-Insulin-Dependent | Altered Intercellular Communication | Activation of adipose tissue macrophages with concomitant low-grade inflammation is believed to play a central role in the development of type 2 diabetes. | 21106861 |
| Inflammation | Altered Intercellular Communication | Reporter and chromatin immunoprecipitation assays identified a previously unrecognized nuclear factor-kB (NF-kB) response element in the TERT promoter, to which NF-kB is recruited during inflammation. | 21106948 |
| Superficial ulcer, Inflammation, Cardiac polyp, Ulcer, Foveolar hyperplasia | Altered Intercellular Communication | We then reviewed the slides of 330 adult patients diagnosed with a cardiac polyp and used semiquantitative or qualitative scales to score foveolar hyperplasia, inflammation, erosion or ulcers, epithelial type, and metaplasia. | 21107084 |
| Inflammation, Fibrosis Assessment | Altered Intercellular Communication | Chronic inflammation, fibrosis of the transverse carpal ligament (TCL), and altered sensory response contribute to the symptoms. | 21107196 |
| Inflammation, Fibrosis Assessment, Neuralgia, Carpal Tunnel Syndrome | Altered Intercellular Communication | Because substance P (SP) is known to be involved in neuropathic pain, chronic inflammation, and fibrosis, the present study evaluated changes in SP levels in patients with CTS. | 21107196 |
| Pain Distress Question, Inflammation, Carpal Tunnel Syndrome | Altered Intercellular Communication | These findings suggest that SP contributes to the pain and inflammation associated with CTS. | 21107196 |
| Inflammation, Chronic periaortitis | Altered Intercellular Communication | Recent studies have suggested that IgG4-related inflammation may play a role in chronic periaortitis. | 21107232 |
| Inflammation, Systemic disease | Altered Intercellular Communication | These pathologic conditions might represent a systemic disorder with fibrotic reaction rather than local inflammation. | 21107232 |
| Inflammation | Altered Intercellular Communication | All four cases were diagnosed with right-sided endplate inflammation and administered intradiscal steroid injections with a non-steroidal anti-inflammatory drug (NSAID). | 21107557 |
| Granulomatous inflammation, Malignant Neoplasms | Altered Intercellular Communication | Surprisingly, the CT-guided fine needle biopsy revealed no malignancy, but granulomatous inflammation and epitheloid cells. | 21108184 |
| Inflammation | Altered Intercellular Communication | Low grade inflammation, with elevated CRP and elevated fibrinogen might contribute. | 21108190 |
| Inflammation | Altered Intercellular Communication | The common risk factor is smoking; active "dentogenic" inflammation should be checked before surgery, particularly before surgery with implants. | 21108190 |
| Chronic sinusitis, inflammation or infection | Altered Intercellular Communication | Moreover, anaerobic bacteria were responsible for infectious inflammation in 66.7% of the cases with the odontogenic form of chronic sinusitis. | 21108501 |
| Scleral thickening, Inflammation | Altered Intercellular Communication | It is characterized with peripheral thickening and opacification of the stroma adjacent to the site of inflammation. | 21108616 |
| Inflammation | Altered Intercellular Communication | Changes in expression of membrane TNF, NF-{kappa}B activation and neutrophil apoptosis during active and resolved inflammation. | 21109521 |
| Exophthalmos, Orbital Pseudotumor | Altered Intercellular Communication | An eight-year-old female presented with symptoms and signs of orbital inflammation and proptosis. | 21109605 |
| Refractory anemias, Inflammation, Renal Insufficiency | Altered Intercellular Communication | NT-proBNP level, in RA patients without co-morbidities potentially influencing this level, is correlated with age, disease activity markers of inflammation, and subclinical renal impairment. | 21110214 |
| Prostate carcinoma, Orbital Pseudotumor | Altered Intercellular Communication | Orbital inflammation after use of zoledronic acid for metastasized prostate carcinoma. | 21110506 |
| Prostate carcinoma, Orbital Pseudotumor | Altered Intercellular Communication | Report of a case of orbital inflammation after the use of zoledronic acid for metastasized prostate cancer. | 21110506 |
| Intraocular inflammation, Endophthalmitis, CTCAE | Altered Intercellular Communication | Changes in visual acuity (VA) and CMT were analyzed, as were safety considerations such as intraocular inflammation and endophthalmitis. | 21110509 |
| Inflammatory abnormality of the eye | Altered Intercellular Communication | The patient was switched to difluprednate 0.05% in an attempt to better control the ocular inflammation. | 21111374 |
| Inflammation, Hernia | Altered Intercellular Communication | At surgery, contrary to the clinical suspicion of a nonbenign lesion, granulomatous inflammation of an indirect inguinal hernia was observed. | 21111459 |
| Chronic dacryocystitis, Nasolacrimal Duct Obstruction | Altered Intercellular Communication | Chronic inflammation of nasolacrimal duct determines obstruction of the lacrimal flow and is called chronic dacryocystitis. | 21112571 |
| Intestinal metaplasia, Inflammation, Atrophic | Altered Intercellular Communication | Predictive factors for body atrophy reversal at Cox-regression analysis were mild atrophy (HR 2.14; 95% CI 1.12-4.1), moderate-severe inflammation (HR 5.3; 95% CI 1.64-17.3), and absence of intestinal metaplasia (HR 2.4; 95% CI 1.2-4.8). | 21112822 |
| Refractory anemias, Inflammation | Altered Intercellular Communication | The correlation of HO-1 concentration in synovial fluid with serum CRP and MMP-3 in joint fluid indicated that HO-1 might be useful as a marker of joint inflammation in RA patients. | 21113640 |
| Inflammation, Villous atrophy, Celiac Disease, Malabsorption Syndrome, Crypt hyperplasia | Altered Intercellular Communication | Celiac disease or gluten-sensitive enteropathy is characterized by malabsorption, chronic inflammation of the small intestine mucosa, villous atrophy and crypt hyperplasia. | 21113713 |
| Inflammation, Osteoporosis, Osteoporosis, Postmenopausal, Refractory anemias, Arthritis | Altered Intercellular Communication | Here, we propose that S1P-targeted therapy is beneficial not only for limiting inflammation but for preventing bone-resorptive disorders, such as osteoporosis, by controlling the migratory behavior of osteoclast precursors and therefore would be good for treating elderly female RA patients who suffer from postmenopausal osteoporosis and arthritis simultaneously. | 21113810 |
| Airway structure | Altered Intercellular Communication | Exhaled nitric oxide (NO), commonly accepted marker of airways inflammation, may be generated both by specific enzymes, NO synthases, as well as by nonenzymatic reduction in its metabolites. | 21114492 |
| Blood coagulation, Cerebrovascular accident | Altered Intercellular Communication | Association of coagulation-related and inflammation-related genes and factor VIIc levels with stroke: the Cardiovascular Health Study. | 21114618 |
| Inflammation, Thrombosis, Cerebrovascular accident | Altered Intercellular Communication | Thrombosis and inflammation are critical in stroke etiology, but associations of coagulation and inflammation gene variants with stroke, and particularly factor VII levels, are inconclusive. | 21114618 |
| Inflammation | Altered Intercellular Communication | Isolated glomerular accumulation of complement component 3 (C3) is typical with variable degrees of glomerular inflammation. | 21114651 |
| Inflammation, Tubulitis Assessment | Altered Intercellular Communication | Inflammation and injury-down PBTs correlated with histologic inflammation and tubulitis, and the inflammation transcripts were greater in kidneys diagnosed as T cell-mediated or borderline rejection. | 21114657 |
| Anemia | Altered Intercellular Communication | Association between the malnutrition-inflammation score and post-transplant anaemia. | 21115668 |
| Inflammation, Tumor necrosis | Altered Intercellular Communication | Biomarkers reflecting nutritional status and inflammation [serum leptin, albumin, interleukin-6 (IL-6), tumour necrosis factor-a (TNF-a) and C-reactive protein] were measured. | 21115668 |
| Inflammation | Altered Intercellular Communication | Inadequate serum 25(OH)D is associated with vascular endothelial dysfunction among healthy middle-aged/older adults, and this is mediated in part by nuclear factor kB-related inflammation. | 21115878 |
| Carcinogenesis, Hepatitis, Liver Cirrhosis | Altered Intercellular Communication | These findings have implications for understanding the evolution from liver inflammation to cirrhosis and associated carcinogenesis. | 21115898 |
| Data types - Address | Altered Intercellular Communication | These findings suggest a possible link between impaired cholinergic neurotransmitter function in AD and Ab pathogenesis. | 21116052 |
| Inflammation, Dental Plaque, Atherosclerotic lesion | Altered Intercellular Communication | Expression of IL-17A in human atherosclerotic lesions is associated with increased inflammation and plaque vulnerability. | 21116822 |
| Communicable Diseases, Inflammation | Altered Intercellular Communication | Interleukin-17A is a pivotal effector cytokine, which modulates immune cell trafficking and initiates inflammation in (auto)immune and infectious diseases. | 21116822 |
| Inflammation, Malnutrition, Chronic Kidney Diseases, Cardiovascular system | Altered Intercellular Communication | Chronic inflammation and malnutrition are associated with increased risk of cardiovascular death in individuals with chronic kidney disease. | 21118362 |
| Periodontal Diseases, Bacterial Infections | Altered Intercellular Communication | Periodontal disease is an inflammatory condition caused by bacterial infections that result in loss of the tooth supporting tissue. | 21118415 |
| Inflammation, Atherosclerosis | Altered Intercellular Communication | Inflammation plays a key role in the development of atherosclerosis. | 21119577 |
| Inflammation, Vasculitis, CTCAE, Systemic Vasculitis | Altered Intercellular Communication | Microscopic polyangiitis (MPA) is an anti-neutrophil cytoplasmic antibody (ANCA)-associated vasculitis characterized by inflammation of small-sized vessels. | 21120499 |
| Orthodontic, Inflammation, Superficial ulcer, Ulceration, CTCAE, Contusions | Altered Intercellular Communication | Gingival inflammation, erosion, ulceration, and contusion were the most common findings in orthodontic patients. | 21121986 |
| Gingivitis, Inflammation | Altered Intercellular Communication | The severity of gingival inflammation was in correlation with oral hygiene status; the poorer oral hygiene, the more severe gingival inflammation was. | 21121986 |
| AGA gene, Alopecia, CTCAE, Disease | Altered Intercellular Communication | Androgenetic alopecia (AGA) is a common androgen-induced progressive disorder; the pathways of which are regulated by local genetic codes and hormonal control. | 21122044 |
| TNF protein, human, Tumor necrosis, Inflammatory Bowel Diseases | Altered Intercellular Communication | Tumour necrosis factor-alpha (TNF-a) inhibitors represent an important treatment advance for a number of inflammatory conditions, including inflammatory bowel disease. | 21122493 |
| Crohn Disease, Acute inflammation | Altered Intercellular Communication | It was recently reported that disordered macrophage cytokine secretion underlies impaired acute inflammation and bacterial clearance in Crohn's disease. | 21122532 |
| Inflammation, Hypoxia, hepcidin | Altered Intercellular Communication | The transcription of hepcidin is controlled by the iron status of the body, hypoxia, and/or inflammation. | 21122575 |
| Crohn Disease, Ulcerative Colitis | Altered Intercellular Communication | To date, only two cases of FP have been reported in patients with inflammatory conditions of the gastrointestinal tract other than ulcerative colitis or Crohn's disease. | 21122579 |
| Airway structure, cell wall thickening | Altered Intercellular Communication | The evaluation of patient showed findings of large airway inflammation with tracheal wall thickening and mucosal irregularities. | 21122581 |
| Inflammation, Hypertension, CTCAE, Cyclophosphamide/Vincristine/Dacarbazine Regimen, Cardiovascular Diseases | Altered Intercellular Communication | Both hypertension and inflammation are major risk factors for cardiovascular disease (CVD) in HDD-CKD patients. | 21124333 |
| Inflammation, Osteopenia | Altered Intercellular Communication | TGF-b1 as possible link between loss of bone mineral density and chronic inflammation. | 21124921 |
| Chronic inflammation | Altered Intercellular Communication | However, patients with chronic inflammation, having increased TGF-b(1) serum-levels, often show reduced bone mineral content and disturbed bone healing. | 21124921 |
| Inflammation, Refractory anemias, Infection, Rheumatoid Arthritis, Amyloidosis | Altered Intercellular Communication | Systemic amyloidosis A (AA), secondary to infections and chronic inflammation, especially rheumatoid arthritis (RA), is the most common form of amyloid deposition. | 21125155 |
| Inflammation, Metabolic Syndrome X | Altered Intercellular Communication | Our results suggest that GPx and CRP, as biomarkers of oxidative stress and chronic inflammation, respectively, have significant role in the pathogenesis of metabolic syndrome. | 21125208 |
| Inflammatory Bowel Diseases, Inflammation | Altered Intercellular Communication | Extraintestinal manifestations of inflammatory bowel disease occur frequently in parallel to the inflammation in the bowel. | 21125512 |
| Gastrointestinal inflammation | Altered Intercellular Communication | The activity of extraintestinal manifestations is often divergent to the activity of intestinal inflammation. | 21125512 |
| Lupus Erythematosus, Lupus Erythematosus, Systemic | Altered Intercellular Communication | Overproduction of inflammation-related cytokines plays an important role in systemic lupus erythematosus (SLE). | 21126942 |
| HD Term Type, Inflammation | Altered Intercellular Communication | HD with the use of VEM resulted in a significant reduction in inflammation and oxidative stress markers. | 21127134 |
| Inflammation, Cardiovascular Diseases | Altered Intercellular Communication | They are involved in the association of chronic inflammation and cardiovascular disease in kidney patients. | 21127137 |
| Inflammatory disorder, Metabolic Syndrome X, Obesity | Altered Intercellular Communication | This imbalance and an excess of ROS induce tissue/cellular damage, which are implicated in chronic inflammation disorders such as obesity, insulin resistance, and metabolic syndromes. | 21127481 |
| Fibrosis Assessment, Hepatitis, Hepatitis B, Chronic | Altered Intercellular Communication | Levels of serum markers of liver inflammation and fibrosis in patients with chronic hepatitis C virus infection according to HIV status and antiretroviral use. | 21128862 |
| Fibrosis Assessment, Hepatic inflammation | Altered Intercellular Communication | In conclusion, serum markers of hepatic inflammation and fibrosis are overexpressed in HIV-HCV-coinfected patients with advanced immunosuppression, while HAART has a "protective" effect. | 21128862 |
| ARCN1 gene, Inflammation | Altered Intercellular Communication | CD4+/CD25+ cells in systemic inflammation in COPD. | 21129004 |
| ARCN1 gene, Inflammation | Altered Intercellular Communication | The results of this study support the possible role of CD4/CD25/CTLA4 cells and adiponectin in the systemic inflammation in COPD. | 21129004 |
| Inflammation, Colorectal Carcinoma | Altered Intercellular Communication | Exploring multilocus associations of inflammation genes and colorectal cancer risk using hapConstructor. | 21129206 |
| Airway structure, Malignant Neoplasms | Altered Intercellular Communication | In conclusion, inflammatory conditions consistent with upper airway infection cause most acquired paediatric neck masses, but malignant neoplasms constitute a significant proportion. | 21129917 |
| Inflammation | Altered Intercellular Communication | Data have suggested a significant role of inflammation in the progression of BPH. | 21130246 |
| Inflammation, Rheumatoid Arthritis, Cardiovascular Diseases | Altered Intercellular Communication | Angiopoietin-2 is highly correlated with inflammation and disease activity in recent-onset rheumatoid arthritis and could be predictive for cardiovascular disease. | 21131273 |
| Refractory anemias, Inflammation, Cyclophosphamide/Vincristine/Dacarbazine Regimen, Cardiovascular Diseases | Altered Intercellular Communication | To investigate whether serum levels of endothelial cell activation markers in early RA patients can serve as biomarkers for inflammation and disease activity, and are associated with radiological progression and development of cardiovascular disease (CVD). | 21131273 |
| Inflammation | Altered Intercellular Communication | Markers of inflammation and disease activity were assessed, as well as radiological damage of hands and feet, at diagnosis and after 2 years. | 21131273 |
| Refractory anemias, Inflammation | Altered Intercellular Communication | Patients with RA had higher levels of VEGF and Angpt-2 at disease onset compared with healthy controls, which correlated with markers of inflammation, but were not predictive of radiological progression after 2 years. | 21131273 |
| Refractory anemias, Inflammation | Altered Intercellular Communication | In early RA, markers of endothelial activation are highly correlated with inflammation and disease activity, but not with radiological progression. | 21131273 |
| Inflammation, Malignant Neoplasms | Altered Intercellular Communication | The mucinous changes are frequently seen with chronic inflammation and/or other metaplastic changes and without cytologic evidence of malignancy. | 21131836 |
| Inflammation, Atrial Fibrillation, Atrial Fibrillation by ECG Finding | Altered Intercellular Communication | Systemic inflammation is associated with atrial fibrillation (AF) and inflammatory processes are involved in the pathophysiology of AF. | 21132345 |
| Anemia, Panhypopituitarism | Altered Intercellular Communication | Severe anaemia caused by panhypopituitarism shows the importance of the hormonal system for erythropoiesis. | 21132394 |
| Inflammation, "Alzheimers Disease | Altered Intercellular Communication | NYU study supports link between gum inflammation and Alzheimer's. | 21133283 |
| Inflammation, Carcinoma | Altered Intercellular Communication | Various types of lesion from inflammation to carcinoma can affect breast. | 21133590 |
| Communicable Diseases | Altered Intercellular Communication | Neutrophil gelatinaase-associated lipocalin (NGAL) is a glycoprotein bound with matrix metalloproteinase-9 (MMP-9) in human neutrophils, and elevated tissue NGAL expression has been documented in different infectious and inflammatory conditions. | 21133718 |
| Inflammation, Periodontitis, Alveolar bone destruction | Altered Intercellular Communication | Within the limits of this study, periodontal inflammation in smoker chronic periodontitis patients seems to lower plasma osteoprotegerin levels and thereby increase the RANKL/OPG ratio, and possibly play a role in the increased susceptibility for alveolar bone destruction in smoker subjects. | 21133939 |
| Inflammation, Diverticulum | Altered Intercellular Communication | In UCD, the inflammation in colonic area harbouring diverticula always affects the overall colonic mucosa in all cases, involving also diverticular orifices. | 21133960 |
| Deficiency of butyryl-CoA dehydrogenase, Inflammation | Altered Intercellular Communication | The endoscopic characteristic of SCAD is that inflammation is mainly detected within the inter-diverticular mucosa without involvement of the diverticular orifices. | 21133960 |
| Diverticular disease of colon, Inflammation | Altered Intercellular Communication | In clinical practice, the incidence of mucosal inflammation in the presence of colonic diverticular disease is low and endoscopy is the mainstay of differential diagnosis. | 21133960 |
| Inflammation, Obesity | Altered Intercellular Communication | Low-grade inflammation is a key feature of obesity, characterized by elevated plasma levels of C-reactive protein (CRP). | 21134343 |
| Inflammation, Squamous cell carcinoma, "Marjolins ulcer", Ulcer | Altered Intercellular Communication | Squamous cell carcinomas are known to occur in ulcers of considerable duration but such rapid growth in such a short duration and rapid lymphatic spread is unusual in Marjolin's ulcer as the lymphatics are usually destroyed because of previous inflammation and scarring. | 21134955 |
| nervous system disorder, Inflammation | Altered Intercellular Communication | CXCL13 was measured by ELISA in 837 subjects: relapsing-remitting MS (RRMS; n=323), secondary progressive MS (SPMS; n=40), primary progressive MS (PPMS; n=24), clinically isolated syndrome (CIS; n=79), other neurological diseases (ONDs; n=181), ONDs with signs of inflammation or viral/bacterial infections (iONDs; n=176) and healthy controls (n=14). | 21135023 |
| Pulmonary Emphysema, Lung Injury | Altered Intercellular Communication | Our data demonstrate the critical role of membrane-localized CFTR in regulating ceramide accumulation and inflammatory signaling in lung injury and emphysema. | 21135173 |
| Inflammation, Temporal Arteritis | Altered Intercellular Communication | Biopsy of the prominent but nontender temporal arteries showed granulomatous inflammation, fragmentation, and duplication of the internal elastic lamina consistent with the temporal arteritis (TA). | 21135707 |
| Inflammation, Ulcer | Altered Intercellular Communication | To investigate whether thermography can be used to detect latent inflammation in pressure ulcers and predict pressure ulcer prognosis in a clinical setting. | 21135794 |
| Inflammation, Metabolic Syndrome X | Altered Intercellular Communication | Low-grade systemic inflammation is emerging as a component of the metabolic syndrome. | 21135979 |
| Communicable Diseases, Inflammation, Hereditary hemochromatosis, hepcidin | Altered Intercellular Communication | Changes in the expression of hepcidin are known to be the key pathogenic factors in hereditary hemochromatosis and are associated with infection and inflammation. | 21136275 |
| Mesenteric Panniculitis | Altered Intercellular Communication | Panniculitis mesenteritis is a rare, benign, and chronic fibrosing inflammation disease with unknown aetiology that affects the mesentery of small bowel and colon. | 21136368 |
| Inflammation, Gallbladder Carcinoma | Altered Intercellular Communication | Preoperative inflammation is a prognostic factor for gallbladder carcinoma. | 21136565 |
| Inflammation, Gallbladder Carcinoma | Altered Intercellular Communication | Inflammation frequently accompanies gallbladder carcinoma (GBC), but its impact on outcome is unclear. | 21136565 |
| Inflammation, TNM Staging System, Neoplasms | Altered Intercellular Communication | In univariable analysis, preoperative inflammation, T, N and M category, TNM stage, radicality of surgery and tumour differentiation were significant prognostic factors. | 21136565 |
| Inflammation, Hepatobiliary Disorder, Diabetes Mellitus | Altered Intercellular Communication | pseudobaselloides Bailey is used as a Chinese folk medicine for treatment of diabetes, inflammation, and liver disease. | 21138371 |
| Fibrosis Assessment, Fatty degeneration, Necrosis with inflammation | Altered Intercellular Communication | At time of first biopsy, fibrosis stage was significantly higher in Asian patients than in Whites (3.0 +- 2.3 vs 1.8 +- 2.0, P < 0.001), as were necro-inflammation and steatosis scores. | 21138506 |
| Inflammation, Chronic Obstructive Airway Disease | Altered Intercellular Communication | [Systemic inflammation among stable ex smokers with chronic obstructive pulmonary disease]. | 21140052 |
| ARCN1 gene, Inflammation, Chronic Obstructive Airway Disease | Altered Intercellular Communication | Low grade systemic inflammation is commonly observed in chronic obstructive pulmonary disease (COPD). | 21140052 |
| ARCN1 gene, Inflammation | Altered Intercellular Communication | To evaluate the extent of systemic inflammation in a group of ex-smokers with COPD in stable condition and its relation with pulmonary function and clinical manifestations. | 21140052 |
| Dyspnea, Inflammation | Altered Intercellular Communication | Patients with systemic inflammation had more AE in the previous year; lower inspiratory capacity, greater dyspnea during the six minutes walk test and worse SGRQ and CRQ scores. | 21140052 |
| ARCN1 gene, Inflammation | Altered Intercellular Communication | Low-grade systemic inflammation was found in 56 of 104 ex-smokers with COPD. | 21140052 |
| Celiac Disease, Crohn Disease, Inflammation | Altered Intercellular Communication | The detection of ASCA in patients with celiac disease allows to suggest that ASCA is not a specific marker for Crohn's disease, but was associated with the inflammation of the small intestine. | 21140083 |
| Inflammation, Atlanto-Axial joint, Atlantooccipital joint structure | Altered Intercellular Communication | A bony fusion of the atlanto-occipital joint after antibiotic treatment resolved the pyogenic inflammation concentrated stress to the damaged atlanto-axial joint, resulting in further damage. | 21140176 |
| Inflammation | Altered Intercellular Communication | It was proposed that asthma/chronic shortness of breath elicit chronic systemic inflammation even in the absence of episodic events. | 21140796 |
| Inflammation | Altered Intercellular Communication | Individuals with asthma/asthma-like symptoms have chronic low levels of systemic inflammation despite the absence of episodic pulmonary events. | 21140796 |
| Inflammation | Altered Intercellular Communication | Understanding chronic systemic inflammation relevant to asthma/asthma-like conditions may lead to design of targeted therapeutics. | 21140796 |
| Airway structure, ARCN1 gene | Altered Intercellular Communication | The TNF-a are involved in airway inflammation and the pathogenetic process of COPD, and may influence the lung function. | 21140973 |
| Exophthalmos, Neoplasms | Altered Intercellular Communication | Inflammations and tumors of the orbit and para-orbital regions may present as proptosis. | 21141324 |
| Inflammation, Corneal Stroma, Corneal Ulcer | Altered Intercellular Communication | Periphpral ulcerative keratitis (PUK) is a disorder consisting of a crescent-shaped destructive inflammation of the perilimbal corneal stroma. | 21141332 |
| Gingivitis, Pain Distress Question, Periodontitis, Gingiva | Altered Intercellular Communication | This case report describes a 2-year follow-up of a 30-year-old, female, chronic periodontitis patient, presenting severe gingival inflammation, sensitivity, pain, and acute gingival lesions that were treated with Er:YAG laser and conventional hand and ultrasonic instruments. | 21142726 |
| Inflammation, hepcidin | Altered Intercellular Communication | Use of a hepcidin-25 cut-off of <= 4 nmol/L allowed the differentiation of IDA from ACD and ACD/IRE, but not the discrimination of ACD from ACD/IRE in patients with severe inflammation. | 21143009 |
| Inflammation, Psoriasis | Altered Intercellular Communication | We previously demonstrated increased expression and activity of double-stranded RNA (dsRNA) receptors in psoriasis lesions, and suggested that this enhanced innate signalling contributed to the maintenance of psoriatic inflammation. | 21143460 |
| Inflammation | Altered Intercellular Communication | CT scans contributed only little to the final diagnosis, whereas increased CRP values and elevated erythrocyte sedimentation rates were more reliable indicators of inflammation in the sinuses. | 21143525 |
| Airway structure | Altered Intercellular Communication | The assessment of the presence of eosinophilic airway inflammation may help in predicting the steroid response in subjects with respiratory symptoms. | 21143751 |
| Airway structure, ARCN1 gene | Altered Intercellular Communication | Fractional exhaled nitric oxide (FENO) is a useful surrogate marker for eosinophilic airway inflammation, but data on the repeatability of FENO measurements in COPD needed for the assessment of significant change are insufficient. | 21143751 |
| Inflammation, Spondylitis | Altered Intercellular Communication | One of the most distinctive features of ankylosing spondylitis (AS) is new bone formation and bone resorption at sites of chronic inflammation. | 21143847 |
| Inflammation, Hyperplasia | Altered Intercellular Communication | Previous studies have indicated that the hyperplasia and inflammation of synovial tissues are significantly related to the pathogenic process of AS. | 21143847 |
| Inflammation, Atherosclerosis, Cardiovascular Diseases, Cyclophosphamide/Vincristine/Dacarbazine Regimen, Diabetes Mellitus, Non-Insulin-Dependent | Altered Intercellular Communication | Low grade inflammation is of pathogenic importance in atherosclerosis and in the development of cardiovascular disease (CVD) and type 2 diabetes (T2D). | 21143859 |
| Inflammation, Ulcerative Colitis | Altered Intercellular Communication | The increased expression of these genes was predominantly observed in samples from UC patients and was associated with more intense inflammation. | 21144017 |
| Airway structure, Abnormality of the paranasal sinuses | Altered Intercellular Communication | to investigate the extent and characteristics of paranasal sinus abnormalities (anatomic and mucosal) on computed tomographic (CT) sinus scans and to determine whether there is a relationship between these findings and eosinophilic airway inflammation in patients with prednisone-dependent asthma. | 21144367 |
| Airway structure, Asthma | Altered Intercellular Communication | we conducted an observational survey of 15 prednisone-dependent asthmatic patients with respect to measures of airway inflammation and CT sinus scans. | 21144367 |
| Inflammation, C32 - zebrafish | Altered Intercellular Communication | Similarly, FPR1 C32T SNP is associated with inflammation and BP related pathways. | 21144844 |
| Cataract, Inflammation, Pain Distress Question | Altered Intercellular Communication | Twice-daily, preservative-free ketorolac 0.45% for treatment of inflammation and pain after cataract surgery. | 21145532 |
| Inflammatory abnormality of the eye | Altered Intercellular Communication | The primary efficacy end point was the percentage of patients with a summed ocular inflammation score of 0 for anterior chamber cell and flare on postoperative day 14. | 21145532 |
| Inflammatory abnormality of the eye | Altered Intercellular Communication | On day 14, 52.5% of ketorolac patients and 26.5% of vehicle patients had an summed ocular inflammation score of 0 (P < .001). | 21145532 |
| Cataract, Inflammation, Pain Distress Question | Altered Intercellular Communication | Twice-daily ketorolac 0.45% was well tolerated and effectively treated inflammation and pain following cataract surgery. | 21145532 |
| Wall of ventricle | Altered Intercellular Communication | B-type natriuretic peptide (BNP) is a neurohormone released from cardiomyocytes in response to volume expansion and increased ventricular wall distension. | 21146031 |
| Pulpitis | Altered Intercellular Communication | A first study on the usefulness of matrix metalloproteinase 9 from dentinal fluid to indicate pulp inflammation. | 21146069 |
| Intraocular inflammation | Altered Intercellular Communication | The primary safety measures were changes from baseline in VA, intraocular pressure (IOP), intraocular inflammation, and production of anti-KH902 antibody. | 21146224 |
| Intraocular inflammation, Retinal Hemorrhage, Low Vision, Toxic effect | Altered Intercellular Communication | Dose-limiting toxicity was defined as intraocular inflammation, elevated IOP, significantly reduced vision, or retinal hemorrhage within 42 days after injection. | 21146224 |
| Inflammation | Altered Intercellular Communication | Obesity-mediated inflammation may damage the brain circuit that regulates food intake. | 21146506 |
| Inflammation, Obesity | Altered Intercellular Communication | Adiposity is associated with chronic low-grade systemic inflammation and increased inflammation in the hypothalamus, a key structure in feeding behavior. | 21146506 |
| Stomatitis | Altered Intercellular Communication | Such restorations may facilitate the development of inflammations in the surface of the oral cavity, referred to as denture stomatitis. | 21147619 |
| Inflammation | Altered Intercellular Communication | Vascular endothelial growth factor (VEGF) is a multifunctional angiogenic cytokine that plays a significant role in inflammation and immune responses implicated in the pathogenesis of inflammatory processes in the implant- surrounding tissues. | 21147629 |
| Inflammation | Altered Intercellular Communication | The study confirmed that increased inflammatory cytokines lead to the persistence of inflammation in obese subjects. | 21147638 |
| Inflammation | Altered Intercellular Communication | TNF--a is one of the most important factors in the development and course of inflammation. | 21147642 |
| Inflammation, Fibrosis Assessment, Lung Diseases, Interstitial | Altered Intercellular Communication | Chronic inflammation and fibrosis are characteristic of interstitial lung diseases (ILD) and are accompanied by neovascularisation. | 21147657 |
| Autoimmune Diseases, Inflammation, Malignant Neoplasms | Altered Intercellular Communication | Because Th17 are potent inducers of tissue inflammation and autoimmunity, these results suggest impact on the clinical management of various types of malignancies treated with alkylating agents and a potential need to optimize CTX-based immunotherapy in patients. | 21148486 |
| Inflammation | Altered Intercellular Communication | Childhood adversity heightens the impact of later-life caregiving stress on telomere length and inflammation. | 21148804 |
| Inflammation, Metabolic Syndrome X, ETV3 wt Allele | Altered Intercellular Communication | To examine prospectively the association of psychological distress with the development of the metabolic syndrome (MetS) and the potential influence of demographic characteristics, health behaviors, and inflammation in this association. | 21148808 |
| Hyperlipidemia, vascular inflammations | Altered Intercellular Communication | Vascular inflammation measured using 18F-FDG PET was increased in healthy individuals without hyperlipidemia but with elevated hsCRP. | 21149476 |
| Inflammation, varicella zoster, Necrotizing, Herpes Simplex Infections, Mapuche Language | Altered Intercellular Communication | Herpes simplex and varicella zoster viruses can cause a wide spectrum of clinical manifestations ranging from severe ARN to slow-progressing necrotizing and non-necrotizing types of inflammation. | 21149747 |
| Cataract, Intraocular inflammation, Retinal Detachment | Altered Intercellular Communication | He developed severe intraocular inflammation and required a pars plana lensectomy, vitrectomy, and scleral buckle after developing a cataract and retinal detachment. | 21149777 |
| Retinal Degeneration, Communicable Diseases, Inflammation | Altered Intercellular Communication | Infection or inflammation within the retina early in life may lead to an autoimmune phenocopy of early-onset inherited retinal degeneration. | 21149784 |
| Dermatitis, Atopic, Inflammation, Data types - Address | Altered Intercellular Communication | Topical pimecrolimus may maintain remissions of atopic dermatitis (AD) by inhibiting subclinical inflammation. | 21150167 |
| Inflammation | Altered Intercellular Communication | This article proposes that inflammation leading to intestinal permeability (a leaky gut) may be responsible for numerous physical and mental abnormalities and associated functional decline. | 21150504 |
| Renal Insufficiency, Electrocardiogram: left ventricle hypertrophy (finding), Chronic Kidney Diseases | Altered Intercellular Communication | The hemodynamic alterations induced by the impairment of renal function explain only in part the development of left ventricular hypertrophy in patients with chronic kidney disease (CKD), who are theoretically exposed to an inappropriate high growth of left ventricular mass (iLVM) due to the activation of neuro-hormonal stressors. | 21150636 |
| Inflammation, Coronary Artery Disease | Altered Intercellular Communication | NT-proBNP and circulating inflammation markers in prediction of a normal myocardial scintigraphy in patients with symptoms of coronary artery disease. | 21152016 |
| Tears body substance, Inflammation | Altered Intercellular Communication | Too close distance of the implant towards dural sac, particularly in case of dural tears, fistulae or overt inflammation. | 21153009 |
| Retinal Neoplasms, Retinitis, Neoplasms | Altered Intercellular Communication | Vasoproliferative retinal tumors are benign tumors of unknown origin often accompanied by vitreoretinal inflammation. | 21153829 |
| Inflammation, Malignant neoplasm of endometrium | Altered Intercellular Communication | Chronic inflammation has been hypothesized to play a role in endometrial cancer development. | 21154749 |
| Inflammation, Ototoxicity | Altered Intercellular Communication | Some of the associated pathogenic changes are amyloid peptide aggregation, excitotoxicity, oxidative stress and inflammation. | 21154880 |
| Airway structure | Altered Intercellular Communication | Fractional exhaled nitric oxide (FENO) is a marker of airway inflammation. | 21155706 |
| melanoma, Inflammation, Neoplasms | Altered Intercellular Communication | Melanoma is often infiltrated by inflammatory and immune cells that might either maintain chronic inflammation, therefore promoting tumour growth, or mount an antitumour response to control tumour outcome. | 21155750 |
| Inflammation, Psoriasis, Dermatitis, Atopic, Dermatologic disorders, Data types - Address | Altered Intercellular Communication | Skin diseases such as psoriasis, characterized by keratinocyte hyperproliferation, and atopic dermatitis (AD), dominated by cutaneous inflammation, might have an impact on viral life cycle and immune response induction. | 21155755 |
| Inflammation | Altered Intercellular Communication | Aberrant expression of epidermal growth factor receptor and its interaction with protein kinase C d in inflammation associated neoplastic transformation of human esophageal epithelium in high risk populations. | 21155880 |
| Inflammation, Alcoholic Intoxication, Chronic | Altered Intercellular Communication | Altogether, our findings reveal that the activation of EGFR and its subsequent interaction with PKCd under inflammatory conditions might positively be attributed to the transformation of normal esophageal epithelia to SCC, which could explain ongoing inflammation in normal mucosa in a population prone to smoking and alcoholism. | 21155880 |
| Inflammation, Alcoholic Intoxication, Chronic | Altered Intercellular Communication | Altogether, our findings reveal that the activation of EGFR and its subsequent interaction with PKCd under inflammatory conditions might positively be attributed to the transformation of normal esophageal epithelia to SCC, which could explain ongoing inflammation in normal mucosa in a population prone to smoking and alcoholism. | 21155880 |
| Intestinal metaplasia, Inflammation, Atrophic | Altered Intercellular Communication | In a total of 190 areas observed with magnifying NBI, histological grading (inflammation, activity, atrophy and intestinal metaplasia) showed significant differences among the classified micromucosal patterns (P < 0.001). | 21155881 |
| Inflammatory Bowel Diseases, Crohn Disease, Inflammation, Ulcerative Colitis | Altered Intercellular Communication | Ulcerative colitis (UC) and Crohn's disease (CD) are two major phenotypes of inflammatory bowel disease (IBD) that present with inflammation of the colon or the entire gastrointestinal tract, respectively. | 21155887 |
| allergic inflammation, Data types - Address | Altered Intercellular Communication | Specific IgE reactivities against a variety of bacterial antigens were observed in a subgroup comprising a third of AD patients and may contribute to allergic inflammation. | 21155910 |
| Communicable Diseases, Inflammation, Edema | Altered Intercellular Communication | The clinical presentation was in the form of an epithelial defect, suspected epithelial down growth, graft oedema with unexplained anterior chamber inflammation and graft-host interface infection. | 21155984 |
| Heart Diseases, Giant Cell Arteritis, vascular inflammations | Altered Intercellular Communication | Bilateral CRAO is a rare disease usually found in patients with cardiac embolic diseases, giant cell arteritis or systemic vascular inflammations. | 21157081 |
| Amyotrophic Lateral Sclerosis, Inflammation, Congenital Abnormality, Small Fiber Neuropathy | Altered Intercellular Communication | nine patients had increased uptake of F-18 FDG, indicating inflammation, in 25 areas of soft tissue and/or bone without concurrent bony abnormalities on CT. presented F-18 FDG PET/CT data may indicate an inflammatory origin of Charcot disease, with secondary bone resorption, possibly due to decreased inhibitory neurogenic inflammatory responses as a result of small fiber neuropathy. | 21157199 |
| Inflammation | Altered Intercellular Communication | There are reported cases of uptake on Octreoscans at other sites of the body due to chronic inflammation, but only one other case has been reported in the brain. | 21157209 |
| Inflammation, Lens Opacities | Altered Intercellular Communication | The main outcome measures included retinal reattachment, visual acuity, intraocular pressure, intraocular inflammation, lens opacity, and HSO emulsification. | 21157397 |
| Airway structure, Respiratory Hypersensitivity | Altered Intercellular Communication | Testing for airway hyperresponsiveness with indirect stimuli as exercise or mannitol has been proposed to better reflect underlying airway inflammation, as compared with methacholine (MCh), believed to act directly on airway smooth muscle cells. | 21159136 |
| Inflammation | Altered Intercellular Communication | There is growing evidence that inflammation plays an important role in atherogenesis. | 21159472 |
| Kidney Failure, Chronic, Inflammation | Altered Intercellular Communication | Upregulation of surrogate markers of inflammation and thrombogenesis in patients with ESRD: pathophysiologic and therapeutic implications. | 21159713 |
| Inflammation, Carcinogenesis | Altered Intercellular Communication | Chemopreventive dietary compounds, such as flavonols, may inhibit colorectal carcinogenesis partly by altering cytokine expression and attenuating inflammation. | 21160427 |
| Arthritis, Erosion of bone | Altered Intercellular Communication | This may represent an autocrine mechanism to limit the degree of bone erosion during joint inflammation. | 21162099 |
| Rheumatoid Arthritis, Arthritis | Altered Intercellular Communication | The level of TSG-6 protein was determined in SF from patients with various arthritides; it was highest in patients with inflammatory conditions such as rheumatoid arthritis, in which it correlated with the amount of TSG-6 immunostaining in the synovium. | 21162099 |
| Keratitis | Altered Intercellular Communication | Corneal inflammation was successfully managed with topical steroids, oral methylprednisolone, and methotrexate. | 21162464 |
| hearing impairment, Inflammation | Altered Intercellular Communication | A 16-year-old male with recurrent inflammation and hearing loss. | 21162483 |
| Granulomatous inflammation | Altered Intercellular Communication | Biopsy specimens demonstrated granulomatous inflammation and acid-fast bacilli with the use of a Fite stain, although a culture and polymerase chain reaction analysis were negative. | 21163172 |
| Chronic Kidney Diseases | Altered Intercellular Communication | Advanced Chronic Renal Disease (CKD) is closely associated with a pro-inflammatory condition, with an increase in triglyceride-rich lipoproteins and decrease in HDL level. | 21163737 |
| AURKAIP1 gene, Inflammation, Pancreatitis | Altered Intercellular Communication | In comparison with the cohort of chronic pancreatitis, not otherwise specified, type 2 AIP cases were less likely to be associated with a history of alcohol abuse, and showed significantly more foci of periductal inflammation and neutrophilic microabscesses. | 21164284 |
| Inflammation, Scleritis, Nodular scleritis | Altered Intercellular Communication | Nodular scleritis was the most common form observed, followed by necrotizing scleritis with inflammation, diffuse scleritis, and necrotizing scleritis without inflammation, respectively. | 21165230 |
| Inflammation, Hyperparathyroidism, Primary, Endothelial dysfunction | Altered Intercellular Communication | Increased markers of inflammation and endothelial dysfunction in patients with mild primary hyperparathyroidism. | 21166606 |
| Inflammation, Endothelial dysfunction | Altered Intercellular Communication | Patients with mild PHPT and normal renal function displayed signs of subclinical inflammation and endothelial dysfunction. | 21166606 |
| ARCN1 gene, Airway structure | Altered Intercellular Communication | 3-Chlorotyrosine in sputum of COPD patients: relationship with airway inflammation. | 21166629 |
| ARCN1 gene, Inflammation, Inflammatory disorder | Altered Intercellular Communication | Contained within the primary granules of neutrophils is the heme enzyme called myeloperoxidase (MPO) that has been used as a biomarker of neutrophilic inflammation in COPD and other inflammatory diseases. | 21166629 |
| Inflammation, Obesity, Abdominal, Diabetes Mellitus, Non-Insulin-Dependent | Altered Intercellular Communication | These findings showed that insulin resistance was associated with CRP levels independent of abdominal obesity in Chinese patients with type 2 diabetes, suggesting that abdominal obesity could only partly explain the link between subclinical inflammation and insulin resistance. | 21167068 |
| Inflammation, Ischemic stroke | Altered Intercellular Communication | Enteral formula containing whey protein may decrease inflammation and increase antioxidant defenses in elderly patients with ischemic stroke, compared to casein-containing formula. | 21167685 |
| Granuloma, Fibrosis Assessment, Ear Inflammation | Altered Intercellular Communication | Morphology in chronic HP is characterized by bronchiolocentric mononuclear inflammation, poorly formed granulomas and variable degree of fibrosis. | 21167698 |
| Inflammation, Fibrosis Assessment, Fatty degeneration | Altered Intercellular Communication | Liver biopsy samples were analyzed (for fibrosis, inflammation, and steatosis) before patients received standard antiviral therapy. | 21167831 |
| Fibrosis Assessment, Fatty degeneration, Hepatitis | Altered Intercellular Communication | Baseline levels of liver inflammation, fibrosis, steatosis, serum interleukin-6 (P = .04), and hepatic TNF-a (P = .007) were significantly higher among postmenopausal women than women of reproductive age. | 21167831 |
| Inflammation, Impaired cognition, millicurie, Data types - Address, amyloid-beta binding | Altered Intercellular Communication | To better investigate inflammation in AD we performed an extensive immunophenotypic and functional analysis of amyloid-beta (Ab) stimulated T lymphocytes in patients with a diagnosis of AD comparing data to those obtained in individuals with mild cognitive impairment (MCI) or aged-matched healthy individuals (HC). | 21167930 |
| Tauopathies, Depression, CTCAE | Altered Intercellular Communication | Hippocampal tauopathy in tau transgenic mice coincides with impaired hippocampus-dependent learning and memory, and attenuated late-phase long-term depression of synaptic transmission. | 21167950 |
| Granulomatous inflammation, Caseous necrosis | Altered Intercellular Communication | Histopathological examination of the biopsy specimen showed granulomatous inflammation and caseous necrosis. | 21168119 |
| Inflammation, Hypoxia, Anemia, hepcidin | Altered Intercellular Communication | The production by hepatocytes of hepcidin, a small defensin-like peptide, is modulated in response to anemia, hypoxia, or inflammation. | 21168677 |
| Inflammation, Renal function, hepcidin, Kidney Transplantation | Altered Intercellular Communication | In conclusion, elevated hepcidin levels in heart and kidney transplant recipients suggest subclinical inflammation and impaired kidney function. | 21168677 |
| Inflammation | Altered Intercellular Communication | Glycodelin (Gd), which is localized in cells of bronchial epithelium, type II pneumocytes and alveolar macrophages in rats and humans, plays an important role in the pulmonary immune response in asthmatic inflammation. | 21168900 |
| Cessation of life, Inflammation | Altered Intercellular Communication | The inflammatory process is related to oxidative stress and inflammation was proven to be a strong determinant of the aging process and to ultimately lead to death. | 21169033 |
| Inflammation | Altered Intercellular Communication | GSTM1 wildtype is associated with reduced mortality among older adults with high levels of inflammation, but not among those with low levels of inflammation. | 21169033 |
| Inflammation, Diabetes Mellitus, Non-Insulin-Dependent | Altered Intercellular Communication | Elevated proinflammatory cytokine production by a skewed T cell compartment requires monocytes and promotes inflammation in type 2 diabetes. | 21169542 |
| Inflammation, Diabetes Mellitus, Non-Insulin-Dependent | Altered Intercellular Communication | Recent work indicates T cells are important mediators of inflammation in a mouse model of T2D. | 21169542 |
| Inflammation, Diabetes Mellitus, Non-Insulin-Dependent | Altered Intercellular Communication | These data indicate that T cells in T2D patients are naturally skewed toward proinflammatory subsets that likely promote chronic inflammation in T2D through elevated cytokine production. | 21169542 |
| Have Autoimmune or Inflammatory Condition | Altered Intercellular Communication | The simultaneous measurement of Th1-related chemokines (CXCL10 and MIP-1a) and of Th2-related chemokine MIP-1b in the serum of patients with AAD would sustain a novel preliminary hypothesis on the immune microenvironment of chronic autoimmune inflammation within adrenal glands. | 21169727 |
| Inflammation, Traumatic | Altered Intercellular Communication | This study demonstrates the feasibility of microdialysis in recovering cytokines for a prolonged time, although there may be some nonresolved methodologic problems with this technique when we try to study the inflammation during traumatic brain injury that could affect the results and make interpretation of microdialysis data prone to difficulties. | 21169825 |
| Inflammation, Atherosclerosis | Altered Intercellular Communication | Adipokines such as adiponectin and resistin, as well as angiogenin, may be associated with inflammation and atherosclerosis. | 21169907 |
| Inflammation, Mixed Connective Tissue Disease | Altered Intercellular Communication | A 45-year old women with MCTD developed multiple LLU's with non-specific inflammation by biopsy. | 21169912 |
| Sialadenitis | Altered Intercellular Communication | Inflammation was the predominant pathological finding (49.5%), of which non-specific chronic sialadenitis constituted the majority (86.9%). | 21170719 |
| Inflammation | Altered Intercellular Communication | Prominent histological findings of chronic inflammation were not evident in either alcoholics or non-alcoholics. | 21171086 |
| Inflammation, Observation Method - Coagulation, Endothelial dysfunction | Altered Intercellular Communication | Other markers of inflammation, coagulation, and endothelial dysfunction increased comparably in both groups during CPB. | 21172477 |
| Inflammation | Altered Intercellular Communication | Alterations in retinal vascular calibre, particularly wider venular calibre, have been independently associated with elevated markers of inflammation and cardiovascular risk in the general population. | 21172929 |
| Refractory anemias, Inflammation | Altered Intercellular Communication | We hypothesized that retinal vascular calibre would be altered in patients with RA, who are known to have both elevated cardiovascular risk and chronic, systemic inflammation. | 21172929 |
| Refractory anemias, Inflammation | Altered Intercellular Communication | The relationship between retinal venular calibre and inflammation was assessed by comparing controls and RA patients with high and lower disease activity. | 21172929 |
| Refractory anemias, Inflammation | Altered Intercellular Communication | also increased with increasing levels of systemic inflammation: 211.6 (21.0) um in controls, 232.3 (22.4) um in RA patients with moderate or lower disease activity and 255.5 (28.3) um in RA patients with high disease activity (P for trend < 0.0001). | 21172929 |
| Refractory anemias, Inflammation | Altered Intercellular Communication | This study demonstrates that RA patients have dilated retinal venular calibre, reflecting systemic inflammation and possibly increased cardiovascular risk. | 21172929 |
| Inflammation | Altered Intercellular Communication | LN was associated with the degree of synovial inflammation. | 21173012 |
| Inflammation, Thrombosis, Thrombocytosis, Polycythemia Vera | Altered Intercellular Communication | Inflammation and thrombosis in essential thrombocythemia and polycythemia vera: different role of C-reactive protein and pentraxin 3. | 21173097 |
| Inflammation, Pancreatic carcinoma | Altered Intercellular Communication | Our results highlight the importance of investigating more specific biomarkers for inflammation that may reflect the biological mechanisms underlying pancreatic cancer in prospective cohort studies. | 21173171 |
| Inflammation, Cardiac dysfunction, Cardiovascular Diseases | Altered Intercellular Communication | Plasma BNP levels increased with respect to the severity of cardiac dysfunction and serum CRP levels, and should therefore be considered a collective or total marker for life-threatening conditions including systemic inflammation, and not simply as a marker of cardiac dysfunction in patients with cardiovascular diseases. | 21173540 |
| Inflammation, Sarcoidosis | Altered Intercellular Communication | Sarcoidosis is a systemic granulomatous inflammation of unknown etiology, and seems to involve the liver parenchyma in most cases. | 21173811 |
| Granulomatous inflammation, Liver carcinoma, Neoplasms | Altered Intercellular Communication | Histology revealed a hepatocellular carcinoma accompanied by T-lymphocytic infiltration and marked granulomatous inflammation, which was surrounding some tumor nodules. | 21173811 |
| Granulomatous inflammation, Fibrosis Assessment | Altered Intercellular Communication | The background liver parenchyma exhibited a moderate degree of fibrosis with granulomatous inflammation. | 21173811 |
| Fever, CTCAE, Chemosis of conjunctiva, Illness (finding), Orbital Cellulitis, Exophthalmos | Altered Intercellular Communication | Orbital cellulitis is an acute inflammation of the orbital content with exophthalmos, chemosis, blepharedema, reduction of eyeball motility and generalized illness, occasionally with fever. | 21174101 |
| Inflammation, Cardiovascular Diseases | Altered Intercellular Communication | The pleiotropic cytokine oncostatin M (OSM), a member of the glycoprotein (gp)130 ligand family, plays a key role in inflammation and cardiovascular disease. | 21174212 |
| Inflammation, Atherosclerosis | Altered Intercellular Communication | Adiponectin and resistin, as well as the novel angiogenetic factor angiogenin, may be associated with inflammation and atherosclerosis. | 21174281 |
| Inflammatory Bowel Diseases, Crohn Disease | Altered Intercellular Communication | Crohn's disease is a chronic inflammatory bowel disease characterized by transmural, granulomatous inflammation. | 21175234 |
| Inflammation, Endotoxemia | Altered Intercellular Communication | Low-grade endotoxemia contributes to chronic inflammation in hemodialysis patients: examination with a novel lipopolysaccharide detection method. | 21175546 |
| Inflammation, Chronic Kidney Diseases, Cardiovascular Diseases | Altered Intercellular Communication | Chronic inflammation has recently been proposed to play a major role in the development of cardiovascular disease and mortality among advanced chronic kidney disease (CKD) patients; however, why advanced CKD promotes chronic inflammation is still unclear. | 21175546 |
| Inflammation, Chronic Kidney Diseases | Altered Intercellular Communication | We hypothesized that a very low level of plasma endotoxin (lipopolysaccharide [LPS]) contributes to chronic inflammation in advanced CKD patients. | 21175546 |
| HD Term Type, Inflammation, Endotoxemia | Altered Intercellular Communication | In conclusion, the present study revealed a significant relationship between LPS and CRP using the novel ESP method, and suggested that very low-grade endotoxemia is contributing to systemic inflammation in HD patients. | 21175546 |
| Myeloma cell, Inappropriate ADH Syndrome | Altered Intercellular Communication | Syndrome of inappropriate antidiuretic hormone secretion associated with plasma cell myeloma. | 21175565 |
| square decimeter, Metabolic Syndrome X, Diabetes Mellitus | Altered Intercellular Communication | Insulin-resistant states, such as metabolic syndrome and diabetes mellitus type 2 (DM2), have been associated with chronic low-grade systemic inflammation. | 21175613 |
| ARCN1 gene, Inflammation, Chronic disease of respiratory system | Altered Intercellular Communication | 1) The scavenging and anti-inflammatory effects of Erdosteine were both confirmed; 2) erdosteine proved to affect eicosanoids significantly; 3) this novel effect underlines the important anti-inflammatory potentialities of the drug in COPD; 4) further investigation is needed in order to assess the capability of Erdosteine in controlling ongoing inflammation in chronic respiratory diseases. | 21176724 |
| Inflammation, Tumor necrosis | Altered Intercellular Communication | Inflammation plays an important role in insulin resistance, and adipocytokines, including tumor necrosis factor-alpha and leptin, can induce insulin resistance. | 21176750 |
| Inflammation, Periodontitis, Malnutrition | Altered Intercellular Communication | Our previous work suggests that periodontitis is associated with malnutrition and inflammation. | 21177012 |
| Inflammation | Altered Intercellular Communication | There was no significant difference between the groups in disease activity, measures of inflammation or endothelial cell activation. | 21177297 |
| ARCN1 gene, Inflammation, Cardiovascular Diseases, Diabetes Mellitus, Obesity | Altered Intercellular Communication | Three COPD groups were identified: group 1 (n=126, 67 years) was characterised by severe airflow limitation (postbronchodilator forced expiratory volume in 1 s (FEV(1)) 38% predicted) and worse performance in most of the respiratory domains of the disease; group 2 (n=125, 69 years) showed milder airflow limitation (FEV(1) 63% predicted); and group 3 (n=91, 67 years) combined a similarly milder airflow limitation (FEV(1) 58% predicted) with a high proportion of obesity, cardiovascular disorders, diabetes and systemic inflammation. | 21177668 |
| Inflammation | Altered Intercellular Communication | Our results indicate that novel anti-inflammatory drugs may resolve imbalanced inflammation and improve outcomes in older people infected with viruses. | 21178458 |
| Inflammation, Cachexia | Altered Intercellular Communication | Protein-energy wasting modifies the association of ghrelin with inflammation, leptin, and mortality in hemodialysis patients. | 21178976 |
| Inflammation, Congenital Abnormality, Anorexia | Altered Intercellular Communication | Ghrelin abnormalities contribute to anorexia, inflammation, and cardiovascular risk in hemodialysis patients, leading to worse outcome. | 21178976 |
| Inflammation, Hypertension, CTCAE, Endothelial dysfunction, Cardiovascular Diseases | Altered Intercellular Communication | Chronic inflammation and endothelial dysfunction may be associated with hypertension and cardiovascular disease. | 21179100 |
| Inflammation, Hypertension, CTCAE, Endothelial dysfunction | Altered Intercellular Communication | This study suggests that inflammation and endothelial dysfunction may have a role in the development of hypertension. | 21179100 |
| Inflammation, Pneumonia, Interstitial, Interstitial Fibrosis Assessment, Nonspecific interstitial pneumonia | Altered Intercellular Communication | An open lung biopsy of the right middle lobe under general anesthesia revealed chronic peribronchial inflammation, mild interstitial fibrosis, and intra-alveolar macrophage infiltration, with some hemosiderin features, compatible with non-specific interstitial pneumonia (NSIP). | 21179284 |
| Inflammation | Altered Intercellular Communication | IL-6 may serve as warning sign, because it increases early in inflammation. | 21179922 |
| Inflammation, Dysplasia, Infection caused by Helicobacter pylori, Metaplasia, Liver regeneration disorder, Atrophic | Altered Intercellular Communication | We evaluated several histopathological parameters, correlating the degree of inflammation, atrophy, metaplasia, regenerative hyperplasia and dysplasia with the presence of H. pylori infection. | 21180246 |
| Communicable Diseases, Inflammation | Altered Intercellular Communication | Tenascin-C (TN-C) is an adhesion-modulating extracellular matrix glycoprotein which is overexpressed in various organs under disease conditions (infection and inflammation). | 21183183 |
| Inflammation, Chronic Kidney Diseases, Cardiovascular morbidity | Altered Intercellular Communication | Chronic kidney disease (CKD) is associated with a state of chronic inflammation and high cardiovascular morbidity and mortality. | 21183183 |
| Airway structure, MS4A2 wt Allele | Altered Intercellular Communication | However, it is uncertain if fraction of exhaled nitric oxide (Feno), which is used as a marker of airway inflammation, and atopy are associated with BMI. | 21183611 |
| Inflammation | Altered Intercellular Communication | Relation of C. pneumoniae antibodies to inflammation and atherosclerosclerosis in dialysis patients. | 21183888 |
| methyldopa, Inflammation, Inflammatory disorder, Uveitis | Altered Intercellular Communication | Although age-related macular degeneration (AMD) is not a classic inflammatory disease like uveitis, inflammation has been found to have an important role in disease pathogenesis and progression. | 21183941 |
| Inflammation, Hypertensive (finding), Endothelial dysfunction, diabetic | Altered Intercellular Communication | Endothelial dysfunction, a common feature among hypertensive and type-2 diabetic patients, has been associated with inflammation and increased concentrations of serum soluble adhesion molecules and resistin, a monocyte-macrophage- and adipocyte-derived cytokine. | 21184654 |
| Esophageal Stricture, Eosinophilic esophagitis, "Extra-osseous Ewings sarcoma | Altered Intercellular Communication | Eosinophilic esophagitis (EoE) is a chronic inflammatory condition that can be complicated by esophageal strictures requiring endoscopic dilation. | 21184880 |
| Tip Breakage, Failure (biologic function) | Altered Intercellular Communication | Failure occurred because of breakage (14) or exuberant inflammation (31). | 21185695 |
| Inflammation, Diabetic Retinopathy, GDC Disease Response Terminology | Altered Intercellular Communication | Inflammation has been linked to the development of diabetic retinopathy (DR). | 21185877 |
| Inflammation, Wrist joint | Altered Intercellular Communication | Epidemiology of suspected wrist joint infection versus inflammation. | 21186086 |
| Communicable Diseases, Inflammation, Arthritis, Infectious | Altered Intercellular Communication | To determine the cumulative prevalence of septic arthritis presenting to the emergency department of an academic medical center and evaluate the use of clinical data to diagnose infection versus inflammation. | 21186086 |
| Atherosclerosis | Altered Intercellular Communication | Resistin is a pro-inflammatory signaling molecule that is thought to contribute to atherosclerosis. | 21187261 |
| Inflammation, Malignant Neoplasms | Altered Intercellular Communication | Intracellular heavy metal nanoparticle storage: progressive accumulation within lymph nodes with transformation from chronic inflammation to malignancy. | 21187947 |
| Inflammation, S100A4 protein, human | Altered Intercellular Communication | Heavy metals from environmental pollution may accumulate in sites far from the entry route and, in genetically conditioned individuals with tissue specificity, may act as cofactors for chronic inflammation or even malignant transformation. | 21187947 |
| Inflammation | Altered Intercellular Communication | We performed a retrospective analysis in 163 SCT recipients of which data had been collected prospectively on intestinal damage (citrulline), inflammation (C-reactive protein), and neutrophil count. | 21188146 |
| Inflammatory Bowel Diseases, Inflammation, Hemorrhage, pancolitis, Ulcer, Ulceration, CTCAE | Altered Intercellular Communication | Colonoscopy showed pancolitis with numerous ulcers; the biopsy showed foci of inflammation, ulceration and hemorrhage in the lamina propria, without features of chronic inflammatory bowel disease. | 21188339 |
| Inflammation, Pain Distress Question | Altered Intercellular Communication | Thus, inflammation may play an important role in bidirectional associations between pain and sleep. | 21188850 |
| Inflammation, Chronic pain | Altered Intercellular Communication | Little is known about concurrent relationships among chronic pain, sleep, and inflammation. | 21188850 |
| Communicable Diseases, Inflammation | Altered Intercellular Communication | CRP levels, plasma glucose levels, lipid profiles, and blood tests were performed to investigate any conditions that might have suggested infection and/or inflammation. | 21189085 |
| Symptoms, Inflammation | Altered Intercellular Communication | Asthma symptoms, lung function, and markers of oxidative stress and inflammation in children exposed to oil refinery pollution. | 21189114 |
| Inflammation, Asthma, Wheezing | Altered Intercellular Communication | We evaluated lung function and markers of inflammation and oxidative stress in children and adolescents with and without asthma or wheezing symptoms living in a petrochemical polluted area (Sarroch, Sardinia) versus a reference area (Burcei). | 21189114 |
| Sneezing, Bronchitis | Altered Intercellular Communication | Children living in Sarroch versus children living in the reference area showed an increase in wheezing symptoms {adjusted prevalence ratio=1.70 [90% confidence interval (CI)=1.01; 2.86]}; a decrease in lung function [variation in FEV(1)=-10.3% (90% CI=-15.0; -6.0%) and in FEF(25-75)=-12.9% (90% CI=-20.7; -4.3%)]; an increase in bronchial inflammation [variation in FE(NO)=+35% (90% CI=11.7; 80.1%)]; and an increase in MDA-dG adducts of +83% (90% CI=22.9; 174.1%). | 21189114 |
| Inflammation | Altered Intercellular Communication | Data from this small study are consistent with the role of environmental pollutants on lung function and inflammation. | 21189114 |
| Inflammation, Decompensated chronic heart failure, Congestive heart failure | Altered Intercellular Communication | Small intestinal function may be altered in decompensated chronic heart failure (CHF) and translocating LPS may contribute to systemic inflammation observed in CHF. | 21190739 |
| Inflammation, Congestive heart failure | Altered Intercellular Communication | Higher LPS concentrations in edematous CHF relate to inflammation. | 21190739 |
| Inflammation, Atherosclerosis | Altered Intercellular Communication | Inflammation is associated with the development of atherosclerotic vascular lesions and some inflammatory parameters are used as cardiovascular (CV) risk markers. | 21190868 |
| Inflammation, Atherosclerosis, Chronic inflammatory disorder | Altered Intercellular Communication | Therefore, accumulation of senescent monocytes may explain, in part, the development of chronic inflammation and atherosclerosis in elderly subjects and in patients with chronic inflammatory diseases. | 21191073 |
| Inflammation, Septic Shock | Altered Intercellular Communication | Midkine significantly increased along with a sequence: health-inflammation (IBD)-systemic inflammation (IBD-SIRS)-severe sepsis/septic shock. | 21192283 |
| Sepsis, Inflammation, Septic Shock | Altered Intercellular Communication | In conclusion, sepsis and septic shock are associated with midkine elevation, substantially more pronounced than in inflammation, even systemic, revealing a new potential mediator of deregulation of neutrophil migration. | 21192283 |
| Inflammation, Granulation procedure | Altered Intercellular Communication | Several recent studies suggest a high-intensity zone (HIZ) within the posterior annulu of lumbar intervertebral disc seen on T2-weighted magnetic resonance (MR) images represents the inflammation in the annulus, an annular tear, and/or vascular granulation tissue. | 21192298 |
| Inflammation, Granulation procedure | Altered Intercellular Communication | There have been studies suggesting that the presence of HIZ reflects inflammation in the annulus, an annular tear, and/or vascular granulation tissue. | 21192298 |
| Schizophrenia, Autistic Disorder, Infection | Altered Intercellular Communication | Infections and inflammatory conditions during pregnancy can dysregulate neural development and increase the risk for developing autism and schizophrenia. | 21192986 |
| Inflammation, Ischemic stroke, Cardiovascular Diseases | Altered Intercellular Communication | Seventy-seven single nucleotide polymorphisms (SNPs) of 53 candidate genes for cardiovascular disease and inflammation were genotyped in 1327 patients with no past history of ischemic stroke. | 21193198 |
| Weight decreased, Inflammation, Sleep Apnea, Obstructive | Altered Intercellular Communication | Effect of weight loss on inflammation in patients with mild obstructive sleep apnea. | 21193295 |
| Inflammation, Sleep Apnea, Obstructive, Cardiovascular Diseases, Osage language | Altered Intercellular Communication | Inflammation may be one mediating mechanism for cardiovascular diseases in obstructive sleep apnea (OSA). | 21193295 |
| Inflammation, Osage language | Altered Intercellular Communication | However, little is known about subclinical inflammation or the effect of lifestyle intervention on inflammation in early stages of OSA. | 21193295 |
| HD Term Type, Chronic Kidney Diseases, Malnutrition, Inflammation | Altered Intercellular Communication | Main exclusion criteria for patients with CKD and HD were severe protein-caloric malnutrition and inflammation (measured by high sensitivity C-reactive protein and interleukin-6 levels). | 21193322 |
| Inflammation, Chronic Kidney Diseases, Anorexia | Altered Intercellular Communication | Inflammation and loss of appetite is the most common problem in patients with chronic kidney disease (CKD). | 21193324 |
| Inflammation, Fibrosis Assessment | Altered Intercellular Communication | The degree of inflammation (0-18) and fibrosis (0-6) according to Ishak score was compared between the initial and the follow-up biopsy. | 21194803 |
| Inflammation, Atrial Fibrillation by ECG Finding | Altered Intercellular Communication | Inflammation, an important mechanism in the pathogenesis of atrial fibrillation (AF), can be regulated by CD36 in monocytes. | 21195211 |
| Inflammation | Altered Intercellular Communication | Annexin A1, a calcium and phospholipid-binding protein, is an important endogenous modulator of inflammation. | 21195640 |
| Inflammation, Chronic Kidney Diseases, Kidney Diseases, Ischemia | Altered Intercellular Communication | Possible sources are an inadequate persistent inflammation and ischemia as a consequence of CKD or caused by the underlying renal disease. | 21195700 |
| Inflammation, Rheumatoid Arthritis | Altered Intercellular Communication | The mechanisms to affect inflammation and clinical outcome in rheumatoid arthritis are only partly understood. | 21196744 |
| Inflammation, Chronic Obstructive Airway Disease | Altered Intercellular Communication | Metabolic phenotype and adipose tissue inflammation in patients with chronic obstructive pulmonary disease. | 21197447 |
| ARCN1 gene, Inflammation, Metabolic Diseases, Chronic Obstructive Airway Disease | Altered Intercellular Communication | Potential links between metabolic derangements and adipose tissue (AT) inflammation in patients with chronic obstructive pulmonary disease (COPD) are unexplored. | 21197447 |
| Inflammation, Chronic Obstructive Airway Disease | Altered Intercellular Communication | Our results suggest that AT inflammation in obese COPD patients relates to insulin resistance. | 21197447 |
| glycation, vascular inflammations, Diabetes Mellitus, Non-Insulin-Dependent | Altered Intercellular Communication | The levels of soluble receptor for advanced glycation end products (sRAGE) may reflect the activity of the advanced glycation end products-RAGE axis, which has been proposed as a potential mechanism of vascular inflammation in patients with type 2 diabetes (T2D). | 21197704 |
| Inflammation, Electrocardiogram: myocardial infarction (finding), Atherosclerosis | Altered Intercellular Communication | Inflammation and genetics play a key role in the pathogenesis of atherosclerosis and its clinical result myocardial infarction (MI). | 21199393 |
| Inflammation, Coronary Arteriosclerosis | Altered Intercellular Communication | It has been recently shown that inflammation may play a role in myocardial ischemia. | 21199731 |
| methyldopa, Inflammation | Altered Intercellular Communication | The results of the current study show that the as-yet undetermined function of variants in the ARMS2/HTRA1 locus might be linked to inflammation, possibly contributing to the development of neovascular AMD. | 21203342 |
| Inflammation, Chronic disease | Altered Intercellular Communication | The plasma proteins are implicated in chronic diseases, inflammation, endothelial function and metabolic signaling. | 21203453 |
| Inflammation, Pancreatitis, Necrosis | Altered Intercellular Communication | contrast enhanced ultrasound provides information on the vascularization of the pancreatic parenchyma, detecting areas of inflammation, necrosis, as well as the residual parenchyma in acute pancreatitis. | 21203596 |
| Inflammation, Necrosis | Altered Intercellular Communication | The analysis of the average value of the maximum acoustic signal intensity (max I) after contrast injection, and of the mean time to signal enhancement appearance (mT): a) superior mesenteric artery: max I 19.37 +/- 8.53 dB, mT 15.85 +/- 4.6 sec; b) inflammation area: max I 14.76 +/- 6.7 dB, mT 15.15 +/- 3.6 sec; c) necrosis area: max I 8.89 +/- 9.91 dB, mT 22.17 +/- 7.9 sec; d) structural ill-defined hypoechoic area: max I 12.03 +/- 5.4 dB, mT 21.67 +/- 4.47 sec. | 21203596 |
| Inflammation, Diabetes Mellitus, Non-Insulin-Dependent | Altered Intercellular Communication | Aging linked to type 2 diabetes increases oxidative stress and chronic inflammation. | 21204649 |
| Inflammation, Diabetes Mellitus | Altered Intercellular Communication | Oxidative stress (OxS) and inflammation are physiopathological mechanisms related to diabetes and aging. | 21204649 |
| Inflammation, Diabetes Mellitus | Altered Intercellular Communication | Our findings suggest that aging, in concert with diabetes, exerts an additive effect on OxS and inflammation. | 21204649 |
| Inflammation, Meningitis | Altered Intercellular Communication | Meningitis is an inflammation of the protective membranes covering the brain and spinal cord caused by bacteria, fungi, or viruses with various clinical symptoms. | 21204701 |
| Refractory anemias, Inflammation, Damage, Rheumatoid Arthritis | Altered Intercellular Communication | IL-17-producing T cells (Th17 cells) are believed to contribute to local inflammation and joint damage in rheumatoid arthritis (RA). | 21204897 |
| Inflammation, Squamous cell carcinoma, SERPINB3 wt Allele | Altered Intercellular Communication | In the oral cavity, chronic inflammation has been observed at various stages of oral squamous cell carcinomas (OSCC). | 21205002 |
| Inflammation | Altered Intercellular Communication | Such inflammation could result from persistent mucosal or epithelial cell colonization by microorganisms. | 21205002 |
| Inflammation, SERPINB3 wt Allele | Altered Intercellular Communication | There is increasing evidence of the involvement of oral bacteria in inflammation, warranting further studies on the association of bacteria with the progression of OSCC. | 21205002 |
| Inflammation, Metabolic Syndrome X, ETV3 wt Allele, Diabetes Mellitus | Altered Intercellular Communication | To examine whether interleukin-1 receptor antagonist (IL-1Ra) is a predictor for clinically incident diabetes in subjects with metabolic syndrome (MetS) and whether its predictive power is independent of C-reactive protein (CRP), an established marker of inflammation. | 21205020 |
| Hepatic inflammation, FAM126A gene | Altered Intercellular Communication | In early-stage HCC, B-HCC patients had better outcomes than C-HCC patients did because of better liver reserve and less hepatic inflammation. | 21207029 |
| Inflammation, Diabetes Mellitus | Altered Intercellular Communication | Prospective studies have reported associations among various markers of inflammation and the incidence of diabetes, and it has been proposed that inflammation has a causal role in the development of diabetes. | 21207147 |
| vascular inflammations | Altered Intercellular Communication | A growing body of evidence has suggested that RAGE may promote vascular inflammation through several mechanisms. | 21208063 |
| Inflammation | Altered Intercellular Communication | Regulation of IL-17 in chronic inflammation in the human lung. | 21208193 |
| Inflammation, Chronic inflammatory disorder | Altered Intercellular Communication | Currently, as there is interest in the role of IL-17-producing cells and Treg cells in chronic inflammatory diseases in humans, we investigated the presence of CD4(+)CD25(+) T-cells and IL-17 in inflammation in the human lung. | 21208193 |
| Pneumonitis | Altered Intercellular Communication | Transcripts for IL-17 were expressed in mononuclear cells and purified T-cells from lung tissue of patients with chronic pulmonary inflammation and, when activated, these cells secrete soluble protein. | 21208193 |
| ARCN1 gene, Inflammation, Depression, CTCAE, Fatigue | Altered Intercellular Communication | Biomarkers of systemic inflammation and depression and fatigue in moderate clinically stable COPD. | 21208443 |
| Inflammation, Depression, CTCAE | Altered Intercellular Communication | It has recently been suggested that depression may be the result of systemic inflammation. | 21208443 |
| ARCN1 gene, Inflammation, Depression, CTCAE, Fatigue | Altered Intercellular Communication | We aimed to explore the association between systemic inflammation and symptoms of depression and fatigue in patients with mainly moderate and clinically stable COPD using a range of inflammatory biomarkers, 2 depression and 2 fatigue scales. | 21208443 |
| Inflammation | Altered Intercellular Communication | Hence, there is a regulatory system in Tenascin expression and plays a vital role in embryogenesis, tumerogenesis and inflammation in remodelling the stroma for cell migration and also for healing. | 21208610 |
| Inflammation, Infectious Endophthalmitis | Altered Intercellular Communication | Excessive inflammation, particularly in the early post-operative phase, should be regarded as infective endophthalmitis. | 21209518 |
| Sepsis, Euthyroid Sick Syndromes | Altered Intercellular Communication | There is ongoing controversy as to whether hormonal changes of the euthyroid sick syndrome are predictors of poor outcome in sepsis and critical illness. | 21210252 |
| Airway structure | Altered Intercellular Communication | Genes in the IL-1 and TNF-a/nuclear factor-kB pathways were overexpressed and correlated with clinical parameters and neutrophilic airway inflammation. | 21211650 |
| allergic inflammation | Altered Intercellular Communication | There is a reduction in AMP PC threshold but not histamine PC threshold during the pollen season, indicating that AMP is a more sensitive indicator of allergic inflammation. | 21211652 |
| Inflammation, Cutis Laxa | Altered Intercellular Communication | Governed by macrophages, the pathogenesis of DC may begin with subclinical inflammation leading to elastolysis and secondary lymphostasis. | 21211847 |
| Arterial calcification, HD Term Type, Amputation of leg through tibia and fibula, CLU protein, human, Whole-Body Irradiation | Altered Intercellular Communication | Furthermore, arterial calcification of below-knee arteries and micro-inflammation represented as CRP were the independent associating factors for low TBI, which was the independent associating factor for PAD and CLI in HD patients. | 21211928 |
| Inflammation, Fibrosis Assessment | Altered Intercellular Communication | Based on previously published anecdotes, the hypothesis is that conjunctiva shows increased inflammation and fibrosis. | 21212848 |
| Inflammation, Fibrosis Assessment, Mast cell infiltration | Altered Intercellular Communication | Main outcome measures were degree of inflammation and fibrosis, mast cell infiltration, and fibroblast count. | 21212848 |
| Inflammation, Mast cell infiltration | Altered Intercellular Communication | The Mann-Whitney test showed no difference between groups in inflammation (P=.17), relative blue intensity (P=.11), degree of mast cell infiltration (P=.61), and fibroblast count (P=.45). | 21212848 |
| Inflammation, Thyroid associated opthalmopathies | Altered Intercellular Communication | While there is a trend toward higher inflammation in the study group, the superior palpebral conjunctiva of patients with thyroid-related orbitopathy is largely spared from autoimmune changes. | 21212848 |
| Inflammation, Coronary Artery Disease | Altered Intercellular Communication | Growing evidence has shown that inflammation plays crucial roles in the development of coronary artery disease (CAD). | 21214401 |
| Inflammation | Altered Intercellular Communication | Therefore, recognition of this combination of peripheral and central nervous inflammation early is important for determining prognoses and perhaps initial treatment. | 21215910 |
| Inflammation, Malignant Neoplasms | Altered Intercellular Communication | Formylpeptide receptor (FPR1) is involved in inflammation, which is important in the pathogenesis of diverse conditions, including common diseases and cancers. | 21216225 |
| Rheumatoid Arthritis, Inflammation, Cardiovascular Diseases | Altered Intercellular Communication | Lipid paradox in rheumatoid arthritis: the impact of serum lipid measures and systemic inflammation on the risk of cardiovascular disease. | 21216812 |
| Inflammation, Cardiovascular Diseases, Refractory anemias, Cyclophosphamide/Vincristine/Dacarbazine Regimen, Rheumatoid Arthritis | Altered Intercellular Communication | To examine the impact of systemic inflammation and serum lipids on cardiovascular disease (CVD) in rheumatoid arthritis (RA). | 21216812 |
| Inflammation, Fibrosis Assessment | Altered Intercellular Communication | Two specimens (50%) of the heart showed areas of mature fat cells in the myocardium, without associated inflammation, without associated fibrosis, without entrapped myocardial cells and without a capsule. | 21217088 |
| Inflammation, Colorectal Carcinoma | Altered Intercellular Communication | Chronic inflammation has been implicated in the etiology of colorectal cancer (CRC), but epidemiologic findings on the association between circulating inflammatory markers and CRC risk are inconsistent. | 21217085 |
| Inflammation | Altered Intercellular Communication | Albumin was included with a negative sign, because its concentration decreases with greater inflammation. | 21217085 |
| Inflammation, Colorectal Carcinoma | Altered Intercellular Communication | Proportional hazard models were used to estimate the HR and 95% CI of CRC in relation to each individual marker and the inflammation z-score. | 21217085 |
| Inflammation, Colorectal Carcinoma | Altered Intercellular Communication | After multivariate adjustment, for the highest versus lowest quartile, there was a statistically significant positive association of CRC risk with fibrinogen: HR = 1.50 (95% CI, 1.05-2.15), P = 0.03; inflammation z-score: HR = 1.65 (95% CI, 1.15-2.35), P = 0.01; and CRP: HR = 1.97 (95% CI, 1.13-3.43, P = 0.02. | 21217085 |
| Vasculitis, Colorectal Carcinoma | Altered Intercellular Communication | These findings indicate that greater levels of fibrinogen, CRP, and blood inflammation z-score are associated with increased CRC risk. | 21217085 |
| Inflammation, Colorectal Carcinoma | Altered Intercellular Communication | The study provides further evidence that precancer inflammation may contribute to CRC etiology. | 21217085 |
| Inflammatory abnormality of the eye | Altered Intercellular Communication | However, ocular inflammation can occur in predisposed individuals. | 21217412 |
| Inflammation | Altered Intercellular Communication | This inflammation is referred to as immune-recovery uveitis. | 21217412 |
| Macular Edema, Cystoid, Inflammation, HIV, Unspecified visual loss | Altered Intercellular Communication | Cystoid macular edema (CME) is a complication that can result from this inflammation and is emerging as a major cause of visual loss in human immunodeficiency virus (HIV)-infected patients. | 21217412 |
| Inflammatory abnormality of the eye, Thickened, Cicatrization | Altered Intercellular Communication | Retinal examination revealed bilateral areas of peripheral scarring from presumed past ocular inflammation and thickening and irregularity at each macula. | 21217412 |
| TNF protein, human, Inflammation, Radiculopathy, Pain Distress Question | Altered Intercellular Communication | TNF-a is a known mediator of inflammation and pain associated with radiculopathy and IVD degeneration. | 21217452 |
| Inflammation | Altered Intercellular Communication | These results suggest this sTNFR to be a potent TNF antagonist with potential to attenuate inflammation in IVD pathology. | 21217452 |
| Sarcoidosis, Neoplasms, Non-necrotizing granulomatous inflammation | Altered Intercellular Communication | Based on the suspicion of spinal tumor, spinal cord biopsy was performed, and the histology revealed multinucleated giant cells, lymphocytes and aggregated histiocytes within granulomatous inflammation, consistent with non-caseating granuloma seen in sarcoidosis. | 21218047 |
| Inflammation | Altered Intercellular Communication | These findings suggest that periodontal inflammation in AMI patients might be associated with higher MMP-8-values compared to the healthy controls. | 21219642 |
| Inflammation, Electrocardiogram: myocardial infarction (finding), Periodontal Diseases | Altered Intercellular Communication | The acute myocardial infarction seems to influence the degree of periodontal inflammation, thus the measurement of the gingival crevicular fluid MMP8 levels seems to be a helpful biochemical test to obtain information about the severity of the periodontal disease. | 21219642 |
| Inflammation, Dysbiosis | Altered Intercellular Communication | Shifts in the composition of resident bacteria have been postulated to drive the chronic inflammation seen in both diseases (the "dysbiosis" hypothesis). | 21219646 |
| Inflammation | Altered Intercellular Communication | We propose a complement-driven immune response which may contribute to the progression of the inflammation and ultimately lead to even more motor neuron injury. | 21220013 |
| APP gene, Inflammation, Aortic Aneurysm, Abdominal | Altered Intercellular Communication | Chronic inflammation play an important role on abdominal aortic aneurysms (AAA) formation. | 21220372 |
| Inflammation | Altered Intercellular Communication | However, it is not known whether this increase is linked to its involvement in alveolar epithelium injury or in systemic inflammation. | 21220996 |
| Inflammation, Diverticular Diseases | Altered Intercellular Communication | Absence of mucosal inflammation in uncomplicated diverticular disease. | 21221786 |
| Inflammation, Diverticulum, Diverticular Diseases | Altered Intercellular Communication | Our purpose was to evaluate the presence of inflammation in the colonic mucosa of patients with symptomatic uncomplicated diverticular disease compared with subjects without diverticula. | 21221786 |
| Inflammation, Diverticular Diseases | Altered Intercellular Communication | Even if based on a small number of patients, the study demonstrates the absence of inflammation in the mucosa of subjects affected by uncomplicated diverticular disease. | 21221786 |
| Inflammation, Atrophic, Metaplasia | Altered Intercellular Communication | The degree of activity (P=0.006) and inflammation (P=0.007) improved significantly after four weeks of successful H. pylori eradication treatment, whereas the degree of atrophy, metaplasia, and Cdx2 expression did not. | 21221798 |
| Airway structure, Asthma | Altered Intercellular Communication | However, effects of obesity/adiposity on airway inflammation are not well known in subjects without asthma. | 21222563 |
| Airway structure, Asthma | Altered Intercellular Communication | We assessed whether fractional exhaled nitric oxide (FeNO), a marker of eosinophilic airway inflammation, was associated with obesity/adiposity in nonasthmatic healthy adults. | 21222563 |
| Inflammation, Bladder Detrusor Muscle | Altered Intercellular Communication | The mRNA expression of a1-AR subtypes in bladder detrusor and posterior urethra was significantly higher in the inflammation group than in the control group (P<0.05). | 21223784 |
| Inflammation, Bladder Detrusor Muscle | Altered Intercellular Communication | While the mRNA expression of a1-AR subtypes in the bladder detrusor and posterior urethra was significantly lower in the inflammation group than in the control group (P<0.05). | 21223784 |
| Inflammation | Altered Intercellular Communication | Biochemical coagulation and inflammation parameters were measured pre-, peri-, and postoperatively. | 21224820 |
| Inflammation, Ventricular failure | Altered Intercellular Communication | Preoperative evaluation of markers of inflammation and neurohumoral activation may provide additional information for predicting right ventricular failure after implantation of an LVAD. | 21225395 |
| Granulomatous inflammation | Altered Intercellular Communication | Neuropathological examination of the removed material showed typical granulomatous inflammation with characteristic infiltrate of lymphocytes, epithelioid macrophages and Langhans-type multi-nucleated giant cells. | 21225513 |
| Inflammation, "Alzheimers Disease", Data types - Address | Altered Intercellular Communication | Inflammation plays a prominent role in Alzheimer disease (AD) pathogenesis. | 21225514 |
| Communicable Diseases, Anemia, Pernicious, Inflammation, Epstein-Barr virus associated gastric carcinoma | Altered Intercellular Communication | Both chronic inflammation and the lack of stomach acid may influence the likelihood of EBV infection of the neoplastic gastric epithelium, but the prevalence of EBV-associated gastric carcinoma among patients with pernicious anemia is unknown. | 21225628 |
| Tumor necrosis, Hypoxia | Altered Intercellular Communication | Tumor necrosis factor blocking therapy alters joint inflammation and hypoxia. | 21225682 |
| Tumor necrosis, Arthritis, Inflammation, Hypoxia | Altered Intercellular Communication | To examine the effect of tumor necrosis factor (TNF) blocking therapy on hypoxia in vivo, macroscopic and microscopic inflammation, and magnetic resonance imaging (MRI) results in patients with inflammatory arthritis. | 21225682 |
| Inflammation | Altered Intercellular Communication | Changes are strongly associated with changes in macroscopic and microscopic measures of joint inflammation and MRI improvement. | 21225682 |
| Inflammation, Hypoxia | Altered Intercellular Communication | These data further strengthen the concept that hypoxia is an important event driving synovial inflammation. | 21225682 |
| Osteitis | Altered Intercellular Communication | NOE must be considered in all patients with temporal bone inflammation, especially those with risk factors and those that fail to improve with more conservative measures. | 21225805 |
| Inflammation, Chronic inflammatory disorder | Altered Intercellular Communication | To determine whether combined higher interleukin-6 (IL-6) and C-reactive protein (CRP) levels are associated with lower pulmonary function levels in older women, accounting for chronic inflammatory diseases, physical function, and other factors associated with inflammation. | 21226682 |
| Inflammation, Electrocardiogram: myocardial infarction (finding), Obesity, Atherosclerosis | Altered Intercellular Communication | Association with adipokines favours the concept that AHSG is involved in atherosclerosis more likely through metabolic pathways (insulin resistance, obesity and adipocyte dysfunction) than by inflammation in patients with post-myocardial infarction. | 21226708 |
| Inflammation, Coronary Artery Disease | Altered Intercellular Communication | Decreased adiponectin and increased inflammation expression in epicardial adipose tissue in coronary artery disease. | 21226932 |
| Sepsis, Inflammation | Altered Intercellular Communication | Procalcitonin is a useful marker to rule out sepsis and systemic inflammation in the ED. | 21228358 |
| Inflammation | Altered Intercellular Communication | The device was functioning intermittently, and no evidence of local or systemic inflammation was observed. | 21228592 |
| Communicable Diseases, Inflammation, Necrosis | Altered Intercellular Communication | The intraoperative findings showed inflammation and necrosis of the right m. abductor pollicis brevis, but no infection with pus.The patient accused the first hospital of irrigating the tissue of his right hand with Octenisept(r). | 21229225 |
| Inflammation, Coronary Artery Disease | Altered Intercellular Communication | Oxidation and inflammation are linked processes playing an important role in the development and progression of coronary artery disease (CAD). | 21231776 |
| Inflammation, Coronary Arteriosclerosis | Altered Intercellular Communication | The relation between oxidation and inflammation markers with myocardial ischemia is still controversial. | 21231776 |
| atherosclerotic, Lupus Erythematosus, Systemic | Altered Intercellular Communication | The decreased CD36 and CD163 expression observed in atherosclerotic and SLE patients, respectively, suggest that these inflammatory conditions modulate these receptors differentially. | 21231894 |
| Inflammation, Pulmonary Emphysema | Altered Intercellular Communication | Increased inflammation in more highly addicted current smokers could influence the CT lung density distribution, which may influence genetic association studies of emphysema phenotypes. | 21232152 |
| Inflammation, Coronary Arteriosclerosis, Angina Pectoris | Altered Intercellular Communication | Clinical characteristics, vascular function, and inflammation in women with angina in the absence of coronary atherosclerosis: the Dallas Heart Study. | 21232706 |
| Inflammation | Altered Intercellular Communication | Cyanate is formed in vivo by breakdown of urea and at sites of inflammation by the phagocyte protein myeloperoxidase. | 21235354 |
| Inflammation, Inflammatory disorder | Altered Intercellular Communication | TGF-bs and their receptors also have an important role in modulation of skin inflammation, proliferation of epidermal cells, and wound healing, and they have been implicated in different types of skin inflammatory disorders. | 21235789 |
| Inflammation, Liver Cirrhosis | Altered Intercellular Communication | Evidence of neutrophil functional defect despite inflammation in stable cirrhosis. | 21236309 |
| Inflammation, Phagocytes, Liver Cirrhosis | Altered Intercellular Communication | In patients with compensated cirrhosis and apparently normal neutrophil function, the 'skin-window' study disclosed a severe phagocytic defect at the site of inflammation. | 21236309 |
| Inflammation, Chronic Obstructive Airway Disease | Altered Intercellular Communication | Activated factor XI and tissue factor in chronic obstructive pulmonary disease: links with inflammation and thrombin generation. | 21236471 |
| ARCN1 gene, Inflammation | Altered Intercellular Communication | This is the first study to show that active FXIa and TF are present in stable COPD patients, who exhibit enhanced systemic inflammation and thrombin generation. | 21236471 |
| Inflammation, Endothelial dysfunction, Atrial Fibrillation by ECG Finding | Altered Intercellular Communication | Inflammation, endothelial dysfunction and metabolic pathways provide possible links between the inflammatory and hypofibrinolytic states in atrial fibrillation. | 21237502 |
| Inflammation, Fibrosis Assessment, Fatty degeneration | Altered Intercellular Communication | However, a positive association between degree of steatosis and hs-CRP was observed (p<0.05) and this effect remained significant after adjusting for BMI, lobular inflammation, hepatocyte ballooning, and fibrosis. | 21238518 |
| Inflammation, Chronic Obstructive Airway Disease | Altered Intercellular Communication | Hemoglobin, erythropoietin and systemic inflammation in exacerbations of chronic obstructive pulmonary disease. | 21238904 |
| Inflammation, Anemia | Altered Intercellular Communication | Systemic inflammation may represent a possible cause of anemia. | 21238904 |
| ARCN1 gene, Inflammation, Chronic Obstructive Airway Disease | Altered Intercellular Communication | We aimed to determine whether systemic inflammation, which is usually up-regulated during exacerbations of COPD (ECOPD) is associated with low hemoglobin levels expressing erythropoietin resistance. | 21238904 |
| Inflammation | Altered Intercellular Communication | Role of nutritional status and inflammation in higher survival of African American and Hispanic hemodialysis patients. | 21239093 |
| Inflammation, Chronic Kidney Diseases | Altered Intercellular Communication | Studies show that inflammation can contribute to an increase in resting energy expenditure in patients with chronic kidney disease; however, findings about total energy expenditure (TEE) have not been reported. | 21239181 |
| Inflammation | Altered Intercellular Communication | Our findings suggest that patients with inflammation have a lower TEE when compared with healthy subjects and patients without inflammation. | 21239181 |
| Inflammation, Malnutrition | Altered Intercellular Communication | Patients new to dialysis with laboratory-based evidence of malnutrition and/or inflammation are likely to report lower levels of physical activity. | 21239185 |
| methyldopa, Inflammation | Altered Intercellular Communication | Nuclear receptors (NRs), including peroxisome proliferator-activated receptor and liver X receptor, have been identified as key regulators of physiological pathways such as lipid metabolic dysregulation and inflammation, pathways that may also be involved in development of AMD. | 21239617 |
| Inflammation, Reperfusion Injury | Altered Intercellular Communication | Endothelial dysfunction accompanied by increased oxidative stress and inflammation with aging may predispose older arteries to greater ischemia-reperfusion (I/R) injury. | 21239631 |
| Inflammation, Anemia | Altered Intercellular Communication | Prevalence of 25-hydroxyvitamin D deficiency in subgroups of elderly persons with anemia: association with anemia of inflammation. | 21239700 |
| Inflammation, Anemia | Altered Intercellular Communication | The prevalence of vitamin D deficiency was 33.3% in the nonanemic population, 56% in anemia of inflammation (AI; P = .008), and 33.0% in unexplained anemia (P = .55). | 21239700 |
| Arterial Stiffness, Rheumatoid Arthritis, Chronic inflammation | Altered Intercellular Communication | Early prediction of increased arterial stiffness in patients with chronic inflammation: a 15-year followup study of 108 patients with rheumatoid arthritis. | 21239744 |
| Disease | Altered Intercellular Communication | Inflammation early in the RA disease course was associated with increased AIx and PWV after 15 years. | 21239744 |
| Cartilage destruction, Inflammation, polychondritis | Altered Intercellular Communication | Cartilage destruction in polychondritis is induced not only by perichondral inflammation, but also by intrinsic factors expressed in chondrocytes themselves, including certain kinds of proteolytic enzymes and apoptosis. | 21239745 |
| Inflammation, Autoimmune Diseases, Communicable Diseases, Anemia, Chronic disease | Altered Intercellular Communication | Inflammation arising from various etiologies, including infection, autoimmune disorders, chronic diseases, and aging, can promote anemia. | 21239806 |
| Inflammation, Anemia | Altered Intercellular Communication | The anemia of inflammation (AI) is most often normocytic and normochromic and is usually mild. | 21239806 |
| Nutritional Deficiency, Inflammation, Anemia | Altered Intercellular Communication | Although many anemic elderly patients can be diagnosed with nutritional deficiency, anemia of chronic inflammation or comorbid diseases that explain their decreased hematocrit, the etiology of anemia in a significant fraction remains obscure. | 21239805 |
| Inflammation, Anemia, hepcidin | Altered Intercellular Communication | Consequently, genetic variation in the expression of these proinflammatory cytokines may influence the development of anemia in elderly patients, both through induction of hepcidin expression (anemia of inflammation) and through cytokine suppression of erythroid colony formation. | 21239805 |
| Inflammation, Ischemic stroke | Altered Intercellular Communication | Antihypertensive drugs and inflammation in acute ischemic stroke as a predictor factor of future cardiovascular mortality. | 21240546 |
| Inflammation, Corneal Opacity | Altered Intercellular Communication | Confocal scan also disclosed intense haze and inflammation at the interface and clusters of hyperreflective round structures resembling epithelial cells within the interface area. | 21240860 |
| Adult Hepatocellular Carcinoma | Altered Intercellular Communication | Usefulness of a modified inflammation-based prognostic system for predicting postoperative mortality of patients undergoing surgery for primary hepatocellular carcinoma. | 21240991 |
| Acute and chronic inflammation | Altered Intercellular Communication | Urease activity or H. pylori density in the antrum was significantly correlated with chronic active inflammation; in contrast, this correlation was not found in the gastric body. | 21241408 |
| Airway structure, ARCN1 gene | Altered Intercellular Communication | Airway inflammation and mannitol challenge test in COPD. | 21241520 |
| Airway structure, ARCN1 gene, Chronic Obstructive Airway Disease | Altered Intercellular Communication | Eosinophilic airway inflammation has successfully been used to tailor anti-inflammatory therapy in chronic obstructive pulmonary disease (COPD). | 21241520 |
| Respiratory Hypersensitivity, AHR wt Allele, Airway structure | Altered Intercellular Communication | Airway hyperresponsiveness (AHR) by indirect challenges is associated with airway inflammation. | 21241520 |
| Airway structure | Altered Intercellular Communication | In mild-moderate COPD mannitol hyperresponsiveness is associated with biomarkers of airway inflammation. | 21241520 |
| ARCN1 gene, Eosinophilic inflammation | Altered Intercellular Communication | The high specificity of mannitol challenge suggests that the test is particularly suitable to exclude eosinophilic airways inflammation, which may facilitate individualized treatment in COPD. | 21241520 |
| Cataract, Intraocular inflammation | Altered Intercellular Communication | To report cases of intraocular inflammation after intracameral injection of a very high dose of cefuroxime at the end of uneventful cataract surgery. | 21241909 |
| Inflammation, ETV3 wt Allele | Altered Intercellular Communication | While MetS and specific cytokine patterns associated with arterial aging, the increases in arterial stiffness and thickness are greater when both MetS and higher cytokine levels are present, suggesting a possible synergistic effect of MetS and inflammation on the arterial wall. | 21241986 |
| palladium, Inflammation | Altered Intercellular Communication | Using more stringent remission criteria resulted in reduced signs and symptoms of inflammation, but the percentage of joints with PD activity was not reduced, even in those without signs or symptoms. | 21242236 |
| Inflammation | Altered Intercellular Communication | These data suggest that clinical criteria are sufficiently insensitive to detect low but clinically relevant levels of inflammation accurately. | 21242236 |
| Inflammation, Metabolic Syndrome X, Osteoporosis, Obesity, MS gene | Altered Intercellular Communication | Metabolic syndrome (MS) has 2 conflicting factors: obesity known to be protective against osteoporosis and an inflammation that activates bone resorption. | 21242648 |
| Inflammation, Obesity | Altered Intercellular Communication | Inflammation might have a more important role in BMD than obesity in the postmenopausal women. | 21242648 |
| Inflammation, Malnutrition | Altered Intercellular Communication | Malnutrition and inflammation determine prognosis of patients with CRS type 4. | 21242681 |
| HD Term Type, Malnutrition, Myocardial Ischemia, Inflammation | Altered Intercellular Communication | The poor survival rate of incident HD patients with a medical history of ischemic heart disease was predicted by malnutrition and inflammation at the start of HD. | 21242681 |
| Inflammation | Altered Intercellular Communication | An increased percentage of pro-inflammatory CD14(+)CD16(+) monocytes might contribute to inflammation in hemodialysis (HD) patients. | 21242682 |
| HD Term Type, Inflammation | Altered Intercellular Communication | Increased pro-inflammatory monocytes are likely to contribute to inflammation in HD patients, and beneficial effect of on-line HDF might be partially mediated by modulating the inflammatory response. | 21242682 |
| Inflammation, Hernia | Altered Intercellular Communication | The clinical presentation depended on the inflammation extension inside the hernia sac and the presence or not of peritoneal contamination. | 21243805 |
| Gingivitis, Dental Plaque | Altered Intercellular Communication | Preterm children had more plaque, a higher degree of gingival inflammation, and more behaviour-management problems than controls. | 21244509 |
| Inflammation, Hyperparathyroidism, Dyslipidemias, Pathology | Altered Intercellular Communication | On-line high-efficiency HDF resulted in enhanced removal and lower basal levels of small, medium-sized and protein-bound solutes, which are markers or causative agents of uraemic pathologies, mainly inflammation, secondary hyperparathyroidism and dyslipidaemia. | 21245130 |
| Inflammation, atherosclerotic | Altered Intercellular Communication | A state of low-grade inflammation accompanies the pathogenesis of atherosclerotic events. | 21245598 |
| Inflammation, Erosion lesion, Fever, CTCAE, Bursitis, Inflammatory | Altered Intercellular Communication | We report the clinical case of a 76 years-old woman with a subacute trochanteric inflammatory pain with low-grade fever and laboratory markers of acute inflammation, associated with the ultrasonographic evidence of bursitis and radiologic evidence of femoral erosions, that resolved after intravenous antibiotherapy. | 21245818 |
| Inflammation, Reactive systemic amyloidosis | Altered Intercellular Communication | Secondary amyloidosis (SA) results of tissue deposition of an acute phase reactant protein produced by chronic inflammation. | 21245821 |
| Inflammation | Altered Intercellular Communication | The variable FDG uptake in SPNs and mediastinal LNs are associated with the high prevalence of inflammation/infection within the chest. | 21247262 |
| Inflammation | Altered Intercellular Communication | Similar SUVmax thresholds however may exist for extrathoracic regions where the prevalence of inflammation/infection is low. | 21247262 |
| Inflammation, Calcinosis | Altered Intercellular Communication | Viral and bacterial patterns induce TLR-mediated sustained inflammation and calcification in aortic valve interstitial cells. | 21247641 |
| Inflammation, CDIPT gene | Altered Intercellular Communication | Patients with PIS showed significant greater changes of inflammation marker levels, including hs-CRP and IL-6, as compared with the non-PIS group. | 21248083 |
| Inflammation, Fibrosis Assessment, Hepatitis, Chronic | Altered Intercellular Communication | To determine whether mean and entropy apparent diffusion coefficient (ADC) values obtained at diffusion-weighted (DW) magnetic resonance (MR) imaging can help detect and stage histopathologic liver fibrosis and grade inflammation activity in patients with chronic hepatitis C. This retrospective study was approved by the institutional review board, and the requirement for informed consent was waived. | 21248235 |
| Inflammation, Chronic Kidney Diseases, Nephritis, Lupus Erythematosus | Altered Intercellular Communication | As systemic inflammation is also thought to contribute directly to the progression of chronic kidney disease (CKD), we assessed this risk in patients with lupus, with and without a diagnosis of nephritis, and also identified modifiable risk factors. | 21248713 |
| Inflammation, Refractory anemias, Rheumatoid Arthritis, Functional Disability, deformities qualifier | Altered Intercellular Communication | Rheumatoid arthritis (RA) is characterized by inflammation of the synovial membrane, which can lead to deformities and functional disability. | 21249408 |
| Inflammation, Tooth structure, Ankylosis | Altered Intercellular Communication | At the 24 months follow-up the root showed no radiographic signs of inflammation, resorption or ankylosis, and the function of the replanted tooth was fully maintained. | 21250776 |
| Inflammation | Altered Intercellular Communication | Extracellular matrix remodeling by cathepsins play an important role in many conditions associated with inflammation. | 21250859 |
| Granulomatous inflammation | Altered Intercellular Communication | In addition to poorly defined granulomatous inflammation, leprosy-like sarcoidal and palisaded granulomatous inflammation has been documented in literature reports of lues. | 21251035 |
| Inflammation, Depression, CTCAE, Diabetes Mellitus | Altered Intercellular Communication | Tertiary outcomes will be biochemical markers reflecting common pathophysiological processes of insulin resistance, inflammation and oxidative damage that are assumed to be intertwined in both diabetes and depression. | 21251307 |
| Inflammation, Carcinogenesis | Altered Intercellular Communication | Inflammation appears to be important in lung carcinogenesis among smokers, but its role among never-smokers is not well established. | 21252117 |
| Inflammation, millicurie | Altered Intercellular Communication | Systemic inflammation is associated with MCI and its subtypes: the Sydney Memory and Aging Study. | 21252552 |
| Presenile dementia, Inflammation, Impaired cognition, millicurie | Altered Intercellular Communication | Raised low-grade systemic inflammation has been associated with dementia, and preliminary studies suggest an association with mild cognitive impairment (MCI). | 21252552 |
| Inflammation, millicurie | Altered Intercellular Communication | Our findings suggest an association between specific inflammatory markers and MCI subtypes, highlight sex differences in the association with MCI, and point to a discrete impact of systemic inflammation on cognition. | 21252552 |
| Inflammation, Intraductal Hyperplasia, Syringofibroadenoma, Acanthoma, Clear Cell, Traumatic injury, Histogenic Process | Altered Intercellular Communication | Because a reactive histogenesis has been postulated for both eccrine syringofibroadenoma and clear cell acanthoma, this case could represent a morphologically biphasic pattern of epidermal and ductal hyperplasia as a consequence of the stasis-induced chronic inflammation coupled with the footwear-induced chronic trauma. | 21252636 |
| Inflammation, biloma | Altered Intercellular Communication | Coagulation of the transition plan in a context of mutation of the prothrombin gene and inflammation induced biloma were the likely predisposing conditions. | 21253403 |
| Inflammation | Altered Intercellular Communication | Resistance training may assist in maintaining or improving muscle volume and reducing low-grade inflammation. | 21253481 |
| malignant disease, Communicable Diseases, Inflammation, Malignant Neoplasms | Altered Intercellular Communication | Haptoglobin (Hp) is produced as an acute phase reactant during inflammation, infection, malignant diseases, and several cancers. | 21253648 |
| Arteritis, Aortitis | Altered Intercellular Communication | US is a quick and noninvasive test to detect inflammation of temporal artery, and FDG-PET is very helpful for early diagnosis of aortitis in GCA. | 21253802 |
| Inflammation, Ulcerative Colitis | Altered Intercellular Communication | Thus, TLR4, CD14, and NF-kBp65 were upregulated significantly in UC, to an extent that reflects the degree of inflammation and thereby might contribute to the occurrence and development of UC. | 21253969 |
| Acute pyelonephritis, Inflammation | Altered Intercellular Communication | In experiment on 40 white rats with acute pyelonephritis HBO decreased inflammation in renal tissue. | 21254635 |
| Inflammation, Electrocardiogram: myocardial infarction (finding) | Altered Intercellular Communication | Treatment with an oral direct thrombin inhibitor decreases platelet activity but increases markers of inflammation in patients with myocardial infarction. | 21255134 |
| Inflammation, Squamous cell carcinoma, Carcinoma | Altered Intercellular Communication | Inflammation is associated with the pathogenesis of carcinoma, including squamous cell carcinoma of the bladder. | 21255800 |
| Inflammation, Chronic pain, Depression, CTCAE | Altered Intercellular Communication | Patients with CIAP usually suffer from chronic pain and associated depression, both of which have been proposed to cause insulin resistance (IR) by such mechanisms as a sustained increase in the corticosteroids and catecholamines, and chronic low grade inflammation. | 21255940 |
| Granulomatous inflammation, Fibrosis Assessment, Dysplasia | Altered Intercellular Communication | Histologic assessment always revealed ureteral fibrosis and in 2 cases accompanying granulomatous inflammation and dysplasia. | 21256392 |
| Inflammation | Altered Intercellular Communication | In conclusion, higher NLR, an emerging marker of inflammation, is associated with an increased risk for long-term mortality in patients admitted with ADHF. | 21257011 |
| ARCN1 gene, Chronic Obstructive Airway Disease | Altered Intercellular Communication | There are increased neutrophils in the lungs of patients with chronic obstructive pulmonary disease (COPD), but it is unclear if this is due to increased inflammatory signal or related to the inherent behavior of the neutrophils. | 21257786 |
| Inflammation | Altered Intercellular Communication | She was diagnosed to have chronic IC, based upon the cystoscopic biopsy finding of chronic inflammation in the bladder wall. | 21258795 |
| Inflammation | Altered Intercellular Communication | However, in daily clinical practice ultrasound (US) imaging with Doppler information is more versatile and often used for fast and dynamic assessment of joint inflammation. | 21259184 |
| Refractory anemias, Inflammation, Edema of bone marrow | Altered Intercellular Communication | Within limits, the OMERACT RAMRIS scores of inflammation in RA patients (bone marrow oedema and synovial enhancement) are comparable to the US colour-fraction measurements using a high-end US scanner. | 21259184 |
| Inflammation | Altered Intercellular Communication | Both imaging modalities detect inflammation although showing different aspects of the inflammatory process in the wrist joint. | 21259184 |
| Airway structure, Asthma, Zinc deficiency | Altered Intercellular Communication | Mouse models of asthma show that zinc deficiency is associated with airway inflammation (AI), which is attenuated by zinc supplements. | 21261783 |
| Celiac Disease, Inflammation, Myocardial Ischemia, Cessation of life | Altered Intercellular Communication | Celiac disease (HR, 1.22; 95% CI, 1.06 to 1.40) and inflammation (HR, 1.32; 95% CI, 1.14 to 1.52) were both associated with death resulting from IHD, whereas latent CD was not (HR, 0.71; 95% CI, 0.34 to 1.50). | 21262996 |
| Gastrointestinal inflammation | Altered Intercellular Communication | Individuals with CD or small intestinal inflammation are at increased risk of incident IHD. | 21262996 |
| Inflammation, Fibrosis Assessment | Altered Intercellular Communication | It has been reported that proinflammatory cytokine dysregulation and neutrophil-dominated inflammation are the main causes of morbidity in cystic fibrosis (CF). | 21263071 |
| Intraocular inflammation, Endophthalmitis, CTCAE, diabetic | Altered Intercellular Communication | The possibility of K. pneumoniae endogenous endophthalmitis should be suspected in diabetic patients presenting with intraocular inflammation. | 21264489 |
| Inflammation, Fibrosis Assessment | Altered Intercellular Communication | Glucocorticoids (GCs) may improve RF in MM by (1) rapid reduction of paraprotein production, (2) lessening inflammation and fibrosis in renal parenchyma, and (3) decreasing serum calcium level. | 21264915 |
| Inflammation | Altered Intercellular Communication | Donor-reactive immune cells seem to have cross-reacted with unknown pathogens on the skin and contributed to inflammation. | 21265283 |
| Refractory anemias, Inflammation | Altered Intercellular Communication | We examined the impact of oral ingestion of a pre-biotic dPP supplement active compound (AC) on serum glycosylation and clinical variables associated with inflammation and general health in patients with RA. | 21266447 |
| Primary malignant neoplasm, Neoplasms | Altered Intercellular Communication | An inflammation-based prognostic score (mGPS) predicts cancer survival independent of tumour site: a Glasgow Inflammation Outcome Study. | 21266974 |
| Inflammation, Cyclophosphamide/Vincristine/Dacarbazine Regimen, Diabetes Mellitus | Altered Intercellular Communication | C-reactive protein (CRP), a marker of inflammation, is associated with diabetes and CVD. | 21267537 |
| Inflammation, Autoimmune Diseases, polychondritis, Traumatic injury, Retinitis Pigmentosa | Altered Intercellular Communication | Relapsing polychondritis (RP) is an autoimmune disease characterized by inflammation and destruction of all type of body cartilage, and the cartilage trauma may be a trigger of the disease in a susceptible person. | 21267573 |
| Inflammation | Altered Intercellular Communication | Serum and organ-associated anti-hemoglobin humoral autoreactivity: association with anti-Sm responses and inflammation. | 21268022 |
| Autoimmune Diseases, Inflammation | Altered Intercellular Communication | The release of hemoglobin (Hb) occurs in some infectious and autoimmune diseases characterized by inflammation. | 21268022 |
| Inflammation, Uveitis | Altered Intercellular Communication | [Frequency of classified forms in endogenous uveitis considering the anatomical location of the inflammation]. | 21268816 |
| Inflammation, Uveitis | Altered Intercellular Communication | To investigate the frequency of classified forms in endogenous uveitis in Asahikawa Medical College considering the anatomical location of the inflammation. | 21268816 |
| Inflammation, Uveitis | Altered Intercellular Communication | We reviewed medical charts of the patients' age at disease onset, unilateral or bilateral uveitis, anatomical location of inflammation and diagnosis of classified form of uveitis. | 21268816 |
| Inflammation, Gastrointestinal Neoplasms | Altered Intercellular Communication | Oxygen free radicals and their reactive derivatives participate in formation of chronic inflammation states, which facilitate development of gastrointestinal tract tumors. | 21268915 |
| Inflammation, Demographics Domain, ETV3 wt Allele | Altered Intercellular Communication | Valsartan administration lowered increased levels of chronic inflammation in both HT Mets patients with DM and in those without DM. | 21269062 |
| Inflammatory Bowel Diseases, Gastrointestinal inflammation | Altered Intercellular Communication | Fecal calprotectin (FC) is a non-invasive marker of gastrointestinal inflammation with advocated diagnostic precision in distinguishing inflammatory bowel disease (IBD) from non-IBD diagnoses. | 21269246 |
| Inflammation, Migraine Disorders, GDC Comorbidity Terminology, Obesity, Pain Disorder | Altered Intercellular Communication | Obesity, comorbid with pain disorders including migraine, shares common pathophysiological characteristics including systemic inflammation, and derangements in adipose-tissue derived cytokines. | 21269300 |
| Neuronal degeneration, "Alzheimers Disease", Data types - Address | Altered Intercellular Communication | Alzheimer's disease (AD) is associated with neuronal degeneration, synaptic loss and deficits in multiple neurotransmitter systems. | 21269332 |
| Retinal Vein Occlusion | Altered Intercellular Communication | Role of inflammation-related gene polymorphisms in patients with central retinal vein occlusion. | 21269700 |
| Inflammation, Diabetes Mellitus | Altered Intercellular Communication | Diabetes is accompanied with a chronic low-grade inflammation, which may in part be mediated by endotoxins derived from Gram-negative bacteria. | 21270197 |
| Inflammation, Metabolic Diseases, Endotoxemia, Diabetes Mellitus | Altered Intercellular Communication | Both prevalent and incident diabetes were associated with endotoxemia, which may link metabolic disorders to inflammation. | 21270197 |
| Inflammation, Hyperglycemia | Altered Intercellular Communication | Responses to critical illness, such as excessive inflammation and hyperglycemia, may trigger detrimental chain reactions that damage cellular proteins and organelles. | 21270330 |
| Inflammation, Atherosclerosis | Altered Intercellular Communication | The reason is unknown, but chronic inflammation may predispose to atherosclerosis. | 21272803 |
| Inflammation, Malnutrition, Albuminuria, Hypoalbuminemia | Altered Intercellular Communication | Hypoalbuminaemia is more strongly associated with inflammation than with albuminuria and malnutrition. | 21273106 |
| Sleep-Disordered Breathing, Glucose Intolerance (disease), Inflammation, Hypoxemia | Altered Intercellular Communication | As sleep-disordered breathing is associated with disorders of glucose metabolism, it was hypothesised that recurrent episodes of hypoxaemia during sleep, and sleep disruption, would be associated with inflammation and glucose intolerance in CF. | 21273357 |
| Infectious Lung Disorder, allergic inflammation | Altered Intercellular Communication | Mice were exposed intranasally to formalin-killed Mycobacterium avium from a patient with hot tub lung (HP strain) or chronic pulmonary infection (non-HP strain), and bronchoalveolar lavage fluids and lung tissues were evaluated for allergic inflammation. | 21273385 |
| Pneumonitis | Altered Intercellular Communication | Dead M. avium HP strain, but not non-HP strain, elicited marked HP-like pulmonary inflammation in wild-type mice. | 21273385 |
| hormone deficiency, Craniofacial Abnormalities | Altered Intercellular Communication | Presenting this second case of Melnick-Needles syndrome associated with growth hormone deficiency, we suggest that this association may be coincidental, but that it may also be a consequence of craniofacial abnormalities or an independent component of the disorder. | 21274303 |
| Communicable Diseases, Noncommunicable Diseases, Inflammation | Altered Intercellular Communication | Intravitreal bevacizumab may result in intraocular inflammation of infectious and non-infectious etiology. | 21275601 |
| Intraocular inflammation, Infectious Endophthalmitis, Uveitis | Altered Intercellular Communication | Existing reports of intraocular inflammation following intravitreal bevacizumab range from uveitis to infectious endophthalmitis. | 21275601 |
| Communicable Diseases, Necrosis, Granulomatous inflammation | Altered Intercellular Communication | Histological examination of a skin biopsy specimen demonstrated granulomatous inflammation with a necrotic centre; screening for an infectious aetiology was negative. | 21276459 |
| Postoperative Hemorrhage | Altered Intercellular Communication | Concerning factors affecting postoperative hemorrhage, significant differences were seen in relation to surgical tooth extraction (P = .008) and acute inflammation findings (P = .007). | 21277059 |
| Airway structure, Respiration Disorders, Bronchial Hyperreactivity, Obstruction | Altered Intercellular Communication | Asthma is a chronic respiratory disease, characterised by airways inflammation, obstruction and hyperresponsiveness. | 21277184 |
| Airway structure | Altered Intercellular Communication | Exhaled NO and exhaled breath condensate (EBC) NO metabolites (nitrites and nitrates) measurements are non-invasive tools to assess airways inflammation. | 21277184 |
| Airway structure, Asthma | Altered Intercellular Communication | Our aim was to investigate the relationships between asthma control and the above-named biomarkers of airways inflammation. | 21277184 |
| Airway structure, Symptoms | Altered Intercellular Communication | This suggests that nitrates, but not nitrites or FENO, reflect an aspect of airways inflammation that is closer related to asthma symptoms. | 21277184 |
| Inflammation, Nasal congestion (finding), Daytime somnolence | Altered Intercellular Communication | This inflammation of the nose leads to nasal congestion and a reduction in sleep quality, resulting in daytime somnolence. | 21277510 |
| Cataract, Intraocular inflammation, Glaucoma, CTCAE, Ocular Hypertension | Altered Intercellular Communication | Main outcome measures were Snellen acuity, intraocular inflammation, adjunctive therapy, cataract, ocular hypertension, or glaucoma. | 21277557 |
| Behavioral and psychological symptoms of dementia, Inflammation | Altered Intercellular Communication | Chronic low-grade inflammation in elderly persons is associated with altered tryptophan and tyrosine metabolism: role in neuropsychiatric symptoms. | 21277567 |
| Inflammation | Altered Intercellular Communication | Recent data suggest that chronic low-grade inflammation, a fundamental characteristic of aging, plays a role. | 21277567 |
| Inflammation | Altered Intercellular Communication | In addition, inflammation was associated with increases in neopterin and nitrite levels and in phenylalanine concentrations at the expense of tyrosine. | 21277567 |
| Behavioral and psychological symptoms of dementia, Inflammation | Altered Intercellular Communication | These findings show that chronic low-grade inflammation in aging is associated with alterations in enzymatic pathways involved in monoamine metabolism and suggest that these alterations might participate in the pathophysiology of neuropsychiatric symptoms in elderly persons. | 21277567 |
| Inflammation, SPOP gene | Altered Intercellular Communication | Inflammation does not seem to play an important role in the pathogenesis of POP. | 21277671 |
| Inflammation, Chronic disease, Homeopathy | Altered Intercellular Communication | Low-grade inflammation in chronic diseases: an integrative pathophysiology anticipated by homeopathy? | 21277692 |
| Inflammation | Altered Intercellular Communication | Pro-inflammatory cytokines and their chronic effect - low-grade inflammation - have been associated with diverse chronic conditions. | 21277692 |
| Inflammation, Lupus Erythematosus | Altered Intercellular Communication | Growth arrest-specific protein 6 (Gas6) and its receptor Axl are known to regulate inflammation and may be implicated in lupus pathogenesis. | 21278074 |
| Inflammation, Dental Plaque | Altered Intercellular Communication | To elucidate the relation between the echolucent plaque on carotid ultrasound and acute inflammation on F-18 FDG carotid PET/CT. | 21279492 |
| Inflammation | Altered Intercellular Communication | Synovial inflammation in patients undergoing arthroscopic meniscectomy: molecular characterization and relationship to symptoms. | 21279996 |
| Inflammation, Wounds and Injuries | Altered Intercellular Communication | Accordingly, we sought to characterize synovial pathology in patients with traumatic meniscal injuries and determine the relationships between inflammation, meniscal and cartilage pathology, and symptoms. | 21279996 |
| Inflammation, Pain Distress Question | Altered Intercellular Communication | Synovial inflammation was present in 43% of the patients and was associated with worse preoperative pain and function scores, independent of age, sex, or cartilage pathology. | 21279996 |
| Degenerative polyarthritis, Inflammation, Wounds and Injuries, Pain Distress Question | Altered Intercellular Communication | Our findings indicate that in patients with traumatic meniscal injury undergoing arthroscopic meniscectomy without radiographic evidence of OA, synovial inflammation occurs frequently and is associated with increased pain and dysfunction. | 21279996 |
| Inflammation | Altered Intercellular Communication | Chemokines may contribute to the development of synovial inflammation in patients with meniscal pathology; they also represent potential therapeutic targets for reducing inflammatory symptoms. | 21279996 |
| Sjogrens Syndrome", Inflammation, physiopathological | Altered Intercellular Communication | MicroRNA expression profiles as biomarkers of minor salivary gland inflammation and dysfunction in Sjogren's syndrome. | 21280008 |
| Sjogrens Syndrome", Inflammation | Altered Intercellular Communication | We generated microRNA microarray profiles from the minor salivary glands of control subjects without Sjogren's syndrome (SS) and patients with SS who had low-grade or high-grade inflammation and impaired or normal saliva production, to identify microRNA patterns specific to salivary gland inflammation or dysfunction. | 21280008 |
| Inflammation, physiopathological | Altered Intercellular Communication | The predicted biologic targets of microRNA associated with inflammation or salivary gland dysfunction identified both overlapping and distinct biologic pathways and processes. | 21280008 |
| Inflammation, physiopathological | Altered Intercellular Communication | Distinct microRNA expression patterns are associated with salivary gland inflammation and dysfunction in patients with SS, and microRNA represent a novel group of potential biomarkers. | 21280008 |
| Granuloma, Inflammation, Non-necrotizing granulomatous inflammation | Altered Intercellular Communication | Cytologic findings were categorized in to three groups as non-caseating granuloma, caseating granuloma and pyo-histiocytic inflammation. | 21280429 |
| Conjunctivitis | Altered Intercellular Communication | Conjunctival and eye lid inflammation was evident in 32.4% of people who had TT recurrence and it was associated with recurrence (OR 3.8, 95% CI: 2.7, 5.4, p < .005). | 21280432 |
| Conjunctivitis | Altered Intercellular Communication | Conjunctival and eye lid inflammation has been found to be strong risk factors for recurrence. | 21280432 |
| Communicable Diseases, Inflammatory abnormality of the eye, Congenital Abnormality | Altered Intercellular Communication | Exclusion criteria included: history of recent acute or chronic ocular inflammation or infection and lid surface abnormalities affecting lid function. | 21281063 |
| Eosinophilic granulomatosis with polyangiitis, Orbital Pseudotumor | Altered Intercellular Communication | A diagnosis of orbital inflammation in Churg-Strauss syndrome was suspected, and the immunosuppressive therapy was increased. | 21281077 |
| Inflammation | Altered Intercellular Communication | Inflammation as well as organ function are strongly associated with NT-proCNP serum concentrations. | 21281508 |
| Inflammation, Glycation End Products, Advanced, Coronary Artery Disease, Obesity | Altered Intercellular Communication | Obesity, a risk factor for coronary artery disease (CAD), is associated with inflammation and reactive oxygen species (ROS) production, while advanced glycation end-products, through their receptor (AGER or RAGE), play an important role on these processes. | 21282351 |
| Inflammation, Glaucoma, CTCAE, Traumatic injury, Corneal Neovascularization | Altered Intercellular Communication | Independent risk factors identified for decreased PKP survival were: 1 or more episodes of reversible rejection, active inflammation at PKP, preexisting corneal vascularization, intraoperative complications, small graft size (<= 7.25 mm), large graft size (>= 8.5 mm), preoperative glaucoma, and a preoperative diagnosis of regraft or trauma. | 21282990 |
| Temporomandibular Joint Disorders, Inflammation | Altered Intercellular Communication | In vivo confocal microscopy can detect subtle corneal changes in an advanced case of TMD, which may be signs of subclinical inflammation. | 21282992 |
| Inflammation, Doctor of Dental Medicine | Altered Intercellular Communication | The main outcome measures were IOP, postoperative changes in Descemet membrane detachment (DMD), healing of the surgical incision, and inflammation of the anterior chamber. | 21282997 |
| Cataract, Keratopathy, Inflammation, Corneal edema | Altered Intercellular Communication | Complications included increased intraocular pressure (9.7%), hypotony (2.4%), cataract (57.1%), silicone oil in anterior chamber (17%), persistent total corneal edema (7.3%), band keratopathy (7.3%), and significant inflammation (2.4%). | 21283158 |
| Inflammation | Altered Intercellular Communication | Elevation of serum c-reactive protein in patients with OAB and IC/BPS implies chronic inflammation in the urinary bladder. | 21284020 |
| Inflammation, Overactive Bladder | Altered Intercellular Communication | Chronic inflammation has been implicated in the development of overactive bladder (OAB) and interstitial cystitis/bladder pain syndrome (IC/BPS). | 21284020 |
| Inflammation | Altered Intercellular Communication | An elevation of C-reactive protein (CRP) has been associated with chronic inflammation and lower urinary tract symptoms. | 21284020 |
| Inflammation | Altered Intercellular Communication | Our data support the association between chronic inflammation of the urinary bladder in patients with OAB or IC/BPS. | 21284020 |
| Inflammation, Heart Injuries | Altered Intercellular Communication | To indicate the pathophysiologic background for cTnT release in Chagas heart injury, inflammation markers, such as C-reactive protein and interleukin 6, were measured in parallel. | 21284445 |
| Inflammation | Altered Intercellular Communication | The highly sensitive assay of cTnT release seems to be related to Chagas heart disease-specific inflammation. | 21284445 |
| Rheumatoid Arthritis, Inflammation, Autoimmune Disorder, CTCAE | Altered Intercellular Communication | Free radicals are involved in the pathogenesis of Rheumatoid arthritis, a systemic autoimmune disorder characterized by unchecked synovial inflammation. | 21284489 |
| Rheumatoid Arthritis | Altered Intercellular Communication | Taken together, this ex vivo study has established that allylpyrocatechol has potent scavenging activity and could be considered as an add-on therapy in the treatment of inflammation-associated disorders like Rheumatoid Arthritis. | 21284489 |
| Celiac Disease, Gastrointestinal inflammation, Intestinal Diseases | Altered Intercellular Communication | Increased concentration of nitric oxide (NO) metabolites, nitrite and nitrate, in the urine is a strong indication of ongoing small intestinal inflammation, which is a hallmark of the enteropathy of coeliac disease (CD). | 21284717 |
| Inflammation | Altered Intercellular Communication | The transient effect of SCIO-469 on acute-phase reactants suggests a complex role of p38 MAPK in inflammation. | 21285160 |
| Inflammation, Aortic Aneurysm, Abdominal | Altered Intercellular Communication | Chemical mediators of inflammation and resolution in post-operative abdominal aortic aneurysm patients. | 21286796 |
| Pneumonia, Ventilator-Associated, Inflammation, Critical Illness, Candida (fungus) | Altered Intercellular Communication | The relationship between Candida species cultured from the respiratory tract and systemic inflammation in critically ill patients with ventilator-associated pneumonia. | 21287306 |
| Inflammation, Candida (fungus) | Altered Intercellular Communication | only in the RT is associated with similar levels of inflammation and worse clinical outcomes compared with patients without Candida in RT secretions. | 21287306 |
| Inflammation, Viremia, Lymphopenia, Neutrophilia (finding) | Altered Intercellular Communication | When patients were segregated into high viral load and low viral load groups during the acute phase, those with high viremia had lymphopenia, lower levels of monocytes, neutrophilia, and signs of inflammation. | 21288813 |
| Inflammation, Muscular Atrophy, Fatty infiltration | Altered Intercellular Communication | Magnetic resonance (MR) parameters evaluated in 68 muscles of upper and lower extremity were muscle atrophy, fatty infiltration and inflammation. | 21288962 |
| Inflammation, Fatty infiltration | Altered Intercellular Communication | Fatty infiltration was far more common than inflammation. | 21288962 |
| Cerebrovascular Disorders, Inflammation, Hypertension, CTCAE, Iris hypoperfusion | Altered Intercellular Communication | Smaller retinal arteriolar calibers are strongly related to hypertension, whereas larger retinal venular calibers are more related to inflammation, cerebral hypoperfusion, and cerebrovascular disease. | 21288987 |
| Diabetes Mellitus, Insulin-Dependent, vascular inflammations, Diabetes Mellitus | Altered Intercellular Communication | Preadolescent children with type 1 diabetes and mean diabetes duration of 4 years displayed evidence of low-intensity vascular inflammation and attenuated FMD measurements. | 21289230 |
| Inflammation, Endothelial dysfunction | Altered Intercellular Communication | These data suggest that endothelial dysfunction and systemic inflammation, known harbingers of future cardiovascular risk, are present even in preadolescent children. | 21289230 |
| Nephritis | Altered Intercellular Communication | ISN Forefronts Symposium 2010 in Sylt, Germany: 'Induction and Resolution of Renal Inflammation'. | 21289596 |
| Inflammation, Glomerulonephritis | Altered Intercellular Communication | The program included basic and clinical aspects of inflammation with a special focus on human and experimental glomerulonephritis. | 21289596 |
| Inflammation, Inflammatory disorder | Altered Intercellular Communication | Distinguished scientists from different fields of inflammation research reported their recent discoveries and discussed emerging topics including the role of resolution for inflammatory processes; the 'new and old' cellular players of innate immunity and their mediators; the fundamental role of T-cell subtypes and chemokines; new aspects of B cell-mediated immune responses; and finally the potential implication of results from basic science for human inflammatory renal disease. | 21289596 |
| Inflammation | Altered Intercellular Communication | Signs of acute inflammation (redness, drainage, dehiscence) also were statistically equivalent. | 21290007 |
| Inflammation, Fibrosis Assessment | Altered Intercellular Communication | Inflammation, resulting in periductal fibrosis and compression of the duct orifices, may be a causative factor. | 21290857 |
| HD Term Type, Inflammation | Altered Intercellular Communication | IDO was negatively correlated with all markers of inflammation in HD patients. | 21292009 |
| Inflammation | Altered Intercellular Communication | It is possible that after its initial upregulation due to chronic inflammation, IDO curtails its own provoking agent, i.e., inflammation. | 21292009 |
| Inflammation, Thin-cap fibroatheroma | Altered Intercellular Communication | Fibroblast activation protein is induced by inflammation and degrades type I collagen in thin-cap fibroatheromata. | 21292680 |
| Inflammation, Atherosclerotic lesion | Altered Intercellular Communication | These ex vivo results are consistent with LTB(4) being the direct product of the reaction catalyzed by LTA4H and its role in promoting monocyte chemotaxis to sites of inflammation, including the artery wall of atherosclerotic lesions. | 21293878 |
| Inflammation, Cardiovascular Diseases | Altered Intercellular Communication | These data provide evidence linking inflammation to adverse outcomes beyond cardiovascular disease. | 21293970 |
| Inflammation, Impaired | Altered Intercellular Communication | Interventions targeting inflammation may prevent lung function impairment. | 21293970 |
| Inflammation, Dental Plaque, Dental caries | Altered Intercellular Communication | PT had more plaque and gingival inflammation and presented more BMP than C. No difference in caries prevalence was found. | 21294392 |
| Gastrointestinal Hemorrhage, Inflammation, Anemia, Traumatic injury | Altered Intercellular Communication | There are many causes of anemia in ICU patient such as gastrointestinal bleeding, anemia of chronic inflammation, trauma or surgery. | 21294425 |
| Inflammation, Prostate Cancer Outcomes Study, Dyslipidemias, Hyperandrogenism | Altered Intercellular Communication | PCOS was found to be associated with dyslipidemia, hyperandrogenism, IR and sub-clinical inflammation. | 21294689 |
| Intraocular inflammation, Uveitis | Altered Intercellular Communication | Retinal cells suppress intraocular inflammation (uveitis) through production of interleukin-27 and interleukin-10. | 21294722 |
| Intraocular inflammation, Uveitis | Altered Intercellular Communication | These results suggest that suppression of intraocular inflammation might be mediated through endogenous production of IL-27 and IL-10 by retinal cells, whereas SOCS proteins induced by IL-27 during uveitis may function to protect the neuroretinal cells from the toxic effects of pro-inflammatory cytokines. | 21294722 |
| Inflammation, Sarcoidosis, Lymphadenopathy | Altered Intercellular Communication | The lymphadenopathy specimens were biopsied via mediastinoscopy, and histological study revealed noncaseating epithelioid granulomatous inflammation consistent with sarcoidosis. | 21295493 |
| Inflammation, Heart failure | Altered Intercellular Communication | Several works have endorsed a significant role of the immune system and inflammation in the pathogenesis of heart failure. | 21296316 |
| APP gene, Inflammation, Aortic Aneurysm, Abdominal | Altered Intercellular Communication | Inflammation is associated with the disruption of the aortic media and appears to play a fundamental role in the progression and development of abdominal aortic aneurysm (AAA). | 21296538 |
| Inflammation | Altered Intercellular Communication | Haptoglobin (Hp) is a genetically determined acute phase protein, the synthesis of which is increased during inflammation. | 21296538 |
| Inflammation, Thrombus of cardiac chamber | Altered Intercellular Communication | Previous studies on pathophysiology suggest a role for endothelial inflammation in atherothrombotic strokes and intracardiac thrombosis in cardioembolic strokes. | 21296900 |
| Inflammation, Experimental Autoimmune Encephalomyelitis | Altered Intercellular Communication | Together these findings demonstrate the presence of inflammation and neuronal stress in multiple sclerosis as well as in experimental autoimmune encephalomyelitis. | 21297130 |
| Inflammation, MS gene, Trauma, Nervous System | Altered Intercellular Communication | Since reduced noradrenaline levels could be permissive for increased inflammation and neuronal damage, these results suggest that methods to raise noradrenaline levels or increase locus coeruleus function may be of benefit in treating multiple sclerosis. | 21297130 |
| Granulomatous inflammation, Granulomatosis with polyangiitis, Systemic disease, Necrotizing vasculitis | Altered Intercellular Communication | Wegener's granulomatosis (WG) is a multisystemic disease of unknown etiology characterized by necrotizing vasculitis and granulomatous inflammation (1-3). | 21297323 |
| AIDS Dementia Complex, Inflammation, Trauma, Nervous System | Altered Intercellular Communication | Persistence of HIV-associated cognitive impairment, inflammation, and neuronal injury in era of highly active antiretroviral treatment. | 21297425 |
| Inflammation, Prostate Cancer Outcomes Study, Leukocytosis | Altered Intercellular Communication | Systemic inflammation and reactive leukocytosis have also been described in PCOS. | 21297528 |
| Inflammation, Thrombocytosis | Altered Intercellular Communication | Therefore, from an etiological perspective, thrombocytosis appears to be at least partially independent from the classical pathways of systemic inflammation. | 21297528 |
| Inflammation, SMAD1 protein, human | Altered Intercellular Communication | Ab-Al seems critical in modulating key AD-related pathways such as glutamatergic transmission, Ca(2+) homeostasis, oxidative stress, inflammation, and neuronal apoptosis. | 21298039 |
| Chronic lymphocytic inflammation, Fibrosis Assessment | Altered Intercellular Communication | Histological examination revealed large areas of fibrosis and focal lymphocytic inflammation mimicking infarction/myocarditis. | 21298287 |
| Diabetes Mellitus | Altered Intercellular Communication | Relationship between erythropoietin responsiveness, insulin resistance, and malnutrition-inflammation-atherosclerosis (MIA) syndrome in hemodialysis patients with diabetes. | 21298620 |
| Pulmonary Emphysema | Altered Intercellular Communication | Inflammation partly masks the presence of emphysema on CT and smoking cessation results in a paradoxical fall in lung density, which resembles rapid progression of emphysema. | 21299472 |
| Inflammation, Fibrosis Assessment, AURKAIP1 gene, Periphlebitis, Lymphoplasmacytic Infiltrate | Altered Intercellular Communication | AIP histology was defined by the presence of lymphoplasmacytic infiltration, periductal inflammation, fibrosis, and periphlebitis. | 21299615 |
| Inflammation, One Vessel Coronary Disease | Altered Intercellular Communication | Serum TRACP5a is a macrophage-derived inflammation marker associated with CVD risk, and with coronary vessel disease and its severity and may be a useful marker for screening and assessment of CVD risk. | 21300043 |
| Disability, Inflammation, Albuminuria, Diabetes Mellitus | Altered Intercellular Communication | To examine the relationship between albuminuria, inflammation, and disability in older adults with diabetes. | 21300788 |
| Inflammation, Albuminuria, Diabetes Mellitus | Altered Intercellular Communication | Albuminuria and inflammation were independent correlates for disability among older adults with diabetes. | 21300788 |
| Disability, Inflammation, Albuminuria, Diabetes Mellitus | Altered Intercellular Communication | There was an interaction of albuminuria and elevated CRP on disability, suggesting that the presence of subclinical inflammation may amplify the effect of albuminuria on disability in older adults living with diabetes. | 21300788 |
| Inflammation | Altered Intercellular Communication | Although his general condition improved, his systemic inflammation and chest radiograph findings did not. | 21301164 |
| biloma, Inflammation | Altered Intercellular Communication | PTBD treatment and additional CT-guided drainage of bilomas helped to reduce intraabdominal inflammation, as shown by reduction of inflammation parameters. | 21301846 |
| Gastrointestinal inflammation | Altered Intercellular Communication | IL-23 is, today, considered the key driver of intestinal inflammation and its role in inflammatory responses is tissue-specific. | 21302302 |
| Inflammatory abnormality of the eye, Traumatic injury, Corneal Diseases | Altered Intercellular Communication | Patients had no corneal disease, ocular inflammation, previous trauma or ocular surgery. | 21302722 |
| Inflammation, Neoplasms, Communicable Diseases, Stenosis Morphology, Traumatic injury, External auditory canal structure | Altered Intercellular Communication | Acquired external auditory canal (EAC) stenosis is described as resulting from a number of different causes such as infection, trauma, neoplasia, inflammation and radiotherapy. | 21303316 |
| Inflammation | Altered Intercellular Communication | These results demonstrate that Nrf2 regulates iron efflux from macrophages through Fpn1 gene transcription and suggest that Nrf2 may control iron metabolism during inflammation. | 21303654 |
| Inflammation | Altered Intercellular Communication | The activation of these pathways may contribute to the progression of inflammation, resulting in motor neuron injury. | 21303685 |
| Inflammation | Altered Intercellular Communication | Microscopic findings indicated that the transmural abscess contained massive inflammatory infiltrate and the cecal mucosa showed ulceration and inflammation with a fibrinous and purulent coating. | 21304040 |
| Inflammation, Aortic Aneurysm, Abdominal | Altered Intercellular Communication | Uptake of USPIO in abdominal aortic aneurysms identifies cellular inflammation and appears to distinguish those patients with more rapidly progressive abdominal aortic aneurysm expansion. | 21304070 |
| Refractory anemias, Rheumatoid Arthritis, destruction joint, Inflammation | Altered Intercellular Communication | Rheumatoid arthritis (RA) is characterized by inflammation and joint destruction, with the degree of damage varying greatly among patients. | 21305530 |
| Nephritis | Altered Intercellular Communication | EBV-DNA extraction supported the EBV involvement in renal tissue suggesting that both etiologic agents might have contributed to renal inflammation. | 21305737 |
| Inflammation | Altered Intercellular Communication | In conclusion, an unfavourable NOS substrate/inhibitor ratio may contribute to the reduced NO bioavailability associated with inflammation. | 21306304 |
| Pulmonary arterial hypertension, Inflammation, Congenital heart disease, Vasculitis, CTCAE, Pulmonary artery aneurysm | Altered Intercellular Communication | We report a rare case of idiopathic pulmonary artery aneurysm (PAA) in a 56-year-old woman without any causative conditions, such as congenital heart disease, inflammation, pulmonary artery hypertension, or systemic vasculitis. | 21308440 |
| Inflammation | Altered Intercellular Communication | The existence of monocyte subsets with distinct roles in homeostasis and inflammation suggests specialization of function. | 21308491 |
| vascular inflammations | Altered Intercellular Communication | Flow cytometric analysis of monocyte subsets and marker expression may provide valuable information on vascular inflammation. | 21308491 |
| Inflammation, Obesity | Altered Intercellular Communication | Furthermore, it is possible that obesity, which induces a chronic state of low-level inflammation in addition to several metabolic sequelae, may modify the impact of these SNPs. | 21308720 |
| Granulomatous inflammation, Hodgkin Disease | Altered Intercellular Communication | The cytologic diagnoses of the 31 adequate procedures included 19 with benign disease (8 reactive lymph nodes and 11 granulomatous inflammation), 8 with lymphoma (2 large B-cell, 2 small lymphocytic, 2 Hodgkin, 1 mantle cell, and 1 T-cell lymphoblastic), 2 with cells suspicious for Hodgkin lymphoma, and 2 cases with atypical cells. | 21308997 |
| Inflammation, Granuloma, Crohn Disease | Altered Intercellular Communication | Pathologic examination revealed inflammation in all layers of the appendiceal wall and noncaseating epithelioid cell granuloma, and a diagnosis of appendiceal Crohn's disease was made. | 21309418 |
| Inflammation | Altered Intercellular Communication | Differentially regulated genes were in the functional areas of inflammation and cell signaling. | 21309737 |
| Inflammation, Chronic hand eczema, Fissure | Altered Intercellular Communication | Case study 6--A 56-year-old male civil engineer with chronic hand eczema presenting as fissures and inflammation. | 21309816 |
| Communicable Diseases, Inflammation, Malignant Neoplasms | Altered Intercellular Communication | FDG-PET/CT is widely used in the management of a variety of malignancies with excellent overall accuracy, despite the potential for false positive results related to infection and inflammation. | 21309995 |
| Inflammation | Altered Intercellular Communication | The correlation between CPCE and ICI suggests a role for CPCE as an independent marker of plaque inflammation. | 21310564 |
| Inflammation, Obesity | Altered Intercellular Communication | Association between obesity history and hand grip strength in older adults--exploring the roles of inflammation and insulin resistance as mediating factors. | 21310808 |
| Inflammation, Obesity | Altered Intercellular Communication | To examine the association between obesity history and hand grip strength, and whether the association is partly explained by subclinical inflammation and insulin resistance. | 21310808 |
| Inflammation | Altered Intercellular Communication | IL-1b receptor antagonist reduces inflammation in hemodialysis patients. | 21310819 |
| Inflammation | Altered Intercellular Communication | Chronic inflammation is highly prevalent in maintenance hemodialysis (MHD) patients and associates with increased mortality. | 21310819 |
| Airway structure, Asthma, Obesity | Altered Intercellular Communication | Airway inflammation is augmented by obesity and fatty acids in asthma. | 21310876 |
| Airway structure, Asthma | Altered Intercellular Communication | This was the first study to demonstrate an increase in neutrophilic airway inflammation in obese asthma. | 21310876 |
| Airway structure, Asthma | Altered Intercellular Communication | In males, saturated and monounsaturated fatty acids were important predictors of neutrophilic airway inflammation in asthma. | 21310876 |
| Inflammation, Crohn Disease | Altered Intercellular Communication | Polymorphisms of the RAGE gene have been described as a factor amplifying inflammation in susceptible patients, but the association with Crohn's disease (CD) is not known. | 21311028 |
| vascular inflammations | Altered Intercellular Communication | Pivotal role of protein kinase Cdelta in angiotensin II-induced endothelial cyclooxygenase-2 expression: a link to vascular inflammation. | 21311042 |
| vascular inflammations | Altered Intercellular Communication | The findings raise the possibility of curtailing endothelial COX-2 expression as a means of limiting or preventing vascular inflammation. | 21311042 |
| Osteomyelitis, Inflammation, bone destruction | Altered Intercellular Communication | Osteomyelitis was diagnosed with the help of and X-ray examination in 14,9%, multispiral computed tomography was informative in 48,4% and scintigraphy demonstrated bone destruction and inflammation in 96,8% of cases. | 21311466 |
| Granulation finding, Inflammation, Microcirculatory Bed | Altered Intercellular Communication | Morphologic analysis showed faster inflammation decrease and granulation as well as lesser microcirculatory disorders in wounds treated with photodynamic therapy. | 21311467 |
| Irritation - emotion, Inflammation | Altered Intercellular Communication | GU AEs and colposcopic findings consistent with mild epithelial irritation and inflammation occurred more commonly among women in the VivaGel arm. | 21311578 |
| Inflammation, Observation Method - Coagulation | Altered Intercellular Communication | Blood transfusion during cardiac surgery is associated with inflammation and coagulation in the lung: a case control study. | 21314930 |
| Inflammation, Observation Method - Coagulation, Transfusion-Related Acute Lung Injury | Altered Intercellular Communication | We hypothesized that blood transfusion is associated with changes in pulmonary and systemic inflammation and coagulation occurring in patients who do not meet the clinical diagnosis of transfusion-related acute lung injury (TRALI). | 21314930 |
| Acute Lung Injury, Inflammation, Observation Method - Coagulation, Transfusion-Related Acute Lung Injury | Altered Intercellular Communication | Transfusion during cardiac surgery is associated with activation of inflammation and coagulation in the pulmonary compartment of patients who do not meet TRALI criteria, an effect that was partly dose-dependent, suggesting transfusion as a mediator of acute lung injury. | 21314930 |
| Sepsis, Inflammation, Disturbance | Altered Intercellular Communication | Hengyan medicinal recipe could not only reduce the systemic inflammation, but also plays a role in bidirectional regulation of the immune disturbance to ameliorate immune suppression of sepsis patients. | 21315002 |
| Inflammation, Disease of mucous membrane, Cardiovascular Diseases | Altered Intercellular Communication | Common oral mucosal diseases, systemic inflammation, and cardiovascular diseases in a large cross-sectional US survey. | 21315218 |
| Inflammation, Periodontitis, Atherosclerosis, Cardiovascular Diseases, Cyclophosphamide/Vincristine/Dacarbazine Regimen | Altered Intercellular Communication | Inflammation of the gingivae (periodontitis) has been associated with raised serum biomarkers of inflammation, sub-clinical markers of atherosclerosis, and increased risk of and/or mortality from cardiovascular disease (CVD). | 21315218 |
| Inflammation, Inflammatory disorder | Altered Intercellular Communication | There remain little information regarding the association between other common oral inflammatory disease, systemic inflammation, and CVD. | 21315218 |
| Inflammation, Disease of mucous membrane | Altered Intercellular Communication | Having oral mucosal disease was associated with systemic inflammation (serum levels of C-reactive protein >= 10 mg/dL) (odds ratio 1.41, 95% CI 1.02-1.94). | 21315218 |
| Oral mucous membrane structure, Inflammation | Altered Intercellular Communication | This is the first study to suggest that common oral mucosal diseases are independently associated with raised markers of systemic inflammation and history of CVD. | 21315218 |
| Inflammation, ETV3 wt Allele, Choline Dehydrogenase, Mitochondrial | Altered Intercellular Communication | In a population with prevalent MetS, low-grade inflammation is independently relevant for CHD, as are serum lipoproteins and smoking status. | 21315565 |
| Inflammation, Adult Hepatocellular Carcinoma | Altered Intercellular Communication | Green tea consumption, inflammation and the risk of primary hepatocellular carcinoma in a Chinese population. | 21315679 |
| FAM126A gene | Altered Intercellular Communication | Potential effect modifications of green tea on associations between primary HCC and alcohol drinking, HBV/HCV infection, and inflammation-related SNPs were suggested. | 21315679 |
| Inflammation, Acute heart failure | Altered Intercellular Communication | Inflammation and reduced endothelial function in the course of severe acute heart failure. | 21316028 |
| Inflammation, Shock, Cardiogenic | Altered Intercellular Communication | Systemic inflammation and elevated circulating levels of the endogenous nitric oxide inhibitor asymmetrical dimethylarginine (ADMA) have been associated with increased risk in cardiogenic shock (CS). | 21316028 |
| Inflammation, Organ Dysfunction Scores, Hypoperfusion | Altered Intercellular Communication | ADMA was related to organ dysfunction and degree of hypoperfusion during CS but showed no correlations to inflammation or hampered vasodilator function. | 21316028 |
| Inflammation, Chronic Kidney Diseases, Chronic malnutrition | Altered Intercellular Communication | The combination of chronic malnutrition and inflammation, often termed malnutrition-inflammation complex syndrome or protein-energy wasting, is common in patients with chronic kidney disease. | 21316133 |
| Cessation of life | Altered Intercellular Communication | We assessed the association of malnutrition-inflammation score (MIS) with all-cause mortality and death-censored transplant loss or death with a functioning transplant in a sample of kidney transplant recipients. | 21316133 |
| Inflammation, Malnutrition | Altered Intercellular Communication | Higher score reflects more severe degree of malnutrition and inflammation status. | 21316133 |
| Inflammation, Fibrosis Assessment | Altered Intercellular Communication | The downregulation of ACE2/angiotensin-(1-7)/-Mas receptor axis as well as AT(2)-receptors may promote fibrosis, proliferation and inflammation in patients with AS. | 21316680 |
| Inflammation, Chronic Kidney Diseases | Altered Intercellular Communication | Serum ferritin often increases with inflammation, and a higher cutoff may be better in those with acute and chronic inflammatory conditions, including those with chronic kidney disease (CKD). | 21317036 |
| Inflammation, Chronic Kidney Diseases | Altered Intercellular Communication | Serum ferritin often increases with inflammation, and a higher cutoff may be better in those with acute and chronic inflammatory conditions, including those with chronic kidney disease (CKD). | 21317036 |
| Pain Distress Question, Inflammation | Altered Intercellular Communication | The efficacy is observed for the main symptoms (pain) and on markers of inflammation (CRP), as well as disease severity in terms of spinal mobility and pulmonary function. | 21317434 |
| Inflammation | Altered Intercellular Communication | However, it is still unclear which environmental cues induce persistent activation of macrophages in vivo and how macrophage-derived effector molecules maintain chronic inflammation and affect resident fibroblasts essential for tissue homeostasis and repair. | 21317534 |
| Inflammation, Varicose Ulcer | Altered Intercellular Communication | We used a complementary approach studying human subjects with chronic venous leg ulcers, a model disease for macrophage-driven chronic inflammation, while establishing a mouse model closely reflecting its pathogenesis. | 21317534 |
| Inflammation | Altered Intercellular Communication | Via enhanced TNF-a and hydroxyl radical release, this macrophage population perpetuated inflammation and induced a p16(INK4a)-dependent senescence program in resident fibroblasts, eventually leading to impaired wound healing. | 21317534 |
| Inflammation, Colitis | Altered Intercellular Communication | We also observed reduced neutrophilic inflammation in an acute mouse model of colitis. | 21317538 |
| glycation, Primary malignant neoplasm, Inflammation, Diabetes Mellitus | Altered Intercellular Communication | The receptor for advanced glycation end products (RAGE) plays a crucial role in several disease processes including diabetes, inflammation, and cancer. | 21317562 |
| Granulomatous, Acute inflammation, Pneumonia | Altered Intercellular Communication | Aspiration pneumonia most often presents in surgical lung biopsies as a granulomatous pneumonia with acute inflammation, microabscesses, and a granulomatous reaction to food or other particulate matter. | 21317714 |
| SLC26A5 gene, Inflammation, Hypertension, CTCAE, Kidney Diseases | Altered Intercellular Communication | This case report highlights that, in accordance with recent literature, PRES is a complication of a unique set of conditions comprising of inflammation, hypertension, immunosupression and nephropathy in different degrees and does not necessarily preclude the use of drugs implicated as inciting agents. | 21318395 |
| Vasculitis, Inflammation | Altered Intercellular Communication | After treatment, inflammation subsided, the exudative lesion shrank, and the frosted branch angiitis improved. | 21319040 |
| Inflammation, Fibrosis Assessment, Hepatitis B | Altered Intercellular Communication | Evaluation of adefovir & lamivudine in chronic hepatitis B: correlation with HBV viral kinetic, hepatic-necro inflammation & fibrosis. | 21321419 |
| Inflammation, Primary malignant neoplasm | Altered Intercellular Communication | In multivariate regression, histological inflammation was associated with an 85% decreased probability of cancer on repeat biopsy (odds ratio; OR 0.15; 95% confidence interval; CI 0.04-0.57; P=0.04). | 21321586 |
| Inflammation, Primary malignant neoplasm | Altered Intercellular Communication | In conclusion, inflammation was independently associated with a significantly decreased risk of cancer on repeat biopsy. | 21321586 |
| Orbital Pseudotumor | Altered Intercellular Communication | A multi-centre case series investigating the aetiology of hypertrophic pachymeningitis with orbital inflammation. | 21322792 |
| Orbital Pseudotumor | Altered Intercellular Communication | This was a retrospective case series of all patients presenting with hypertrophic pachymeningitis in association with orbital inflammation in 4 centres. | 21322792 |
| Pachymeningitis, Granulomatosis with polyangiitis, Orbital Pseudotumor | Altered Intercellular Communication | We postulate that the combination of orbital inflammation and pachymeningitis is strongly suggestive of Wegener granulomatosis, although it may take a number of years to confirm. | 21322792 |
| Inflammation | Altered Intercellular Communication | Permanent sections showed chronic inflammation and foreign body reaction. | 21323272 |
| Airway structure | Altered Intercellular Communication | Asthma manifests as TH2-dominant airway inflammation regulated by inducible T-cell kinase (ITK). | 21323647 |
| Inflammation | Altered Intercellular Communication | It is hypothesized that dysregulation of the autonomic nervous system (ANS) leads to increased inflammation via the cholinergic anti-inflammatory pathway. | 21323913 |
| Inflammation | Altered Intercellular Communication | This association supports the hypothesis that dysregulation of the ANS may lead to increased inflammation early in adulthood. | 21323913 |
| Inflammation, Psoriasis | Altered Intercellular Communication | Evaluation of soluble CD163 as a marker of inflammation in psoriasis. | 21323937 |
| Airway structure, Communicable Diseases, Chronic Obstructive Airway Disease, ARCN1 gene | Altered Intercellular Communication | Progressive airway inflammation and susceptibility to the airway colonisation and infection are characteristic for the pathophysiology of chronic obstructive pulmonary disease (COPD). | 21324122 |
| Communicable Diseases, Inflammation | Altered Intercellular Communication | High suPAR serum concentrations are suggested to reflect the activation of the immune system in circumstances of inflammation and infection, and have been associated with increased mortality in different populations of non-intensive care patients. | 21324198 |
| Inflammation, Metabolic Diseases, Myoglobinuria, Toxic effect, Communicable Diseases, Endocrine System Diseases, Traumatic injury | Altered Intercellular Communication | The differential diagnosis of myoglobinuria includes multiple etiologies, such as infection, inflammation, trauma, endocrinopathies, drugs toxicity, and primary metabolic disorders. | 21324494 |
| Inflammation, Sarcoidosis | Altered Intercellular Communication | Quercetin reduces markers of oxidative stress and inflammation in sarcoidosis. | 21324570 |
| Inflammation, Sarcoidosis | Altered Intercellular Communication | Moreover, quercetin supplementation also reduced markers of oxidative stress and inflammation in the blood of sarcoidosis patients. | 21324570 |
| Inflammation, Sarcoidosis | Altered Intercellular Communication | Sarcoidosis patients might benefit from the use of antioxidants, such as quercetin, to reduce the occurring oxidative stress as well as inflammation. | 21324570 |
| Fibrosis Assessment, Fatty Liver Disease | Altered Intercellular Communication | In NASH lobular inflammation (OR, 3.77; 95%CI, 1.01-24.22) and RBP4 score (4.87; 1.003-23.65) were the only risk factors for fibrosis >=2 at logistic regression analysis. | 21324757 |
| Inflammation, Pain Distress Question | Altered Intercellular Communication | The involvement of the NOP-pN/OFQ system in inflammation, impaired immune function, and pain has to be further elucidated. | 21324928 |
| Chronic inflammation | Altered Intercellular Communication | Resistance to erythropoiesis-stimulating agents (ESAs) is often associated with chronic inflammation. | 21325348 |
| Inflammation, Anemia, Cardiovascular Diseases | Altered Intercellular Communication | Here, we investigated how anaemia, ESA resistance and the plasma levels of biological markers of inflammation could influence all-cause and cardiovascular disease morbidity and mortality. | 21325348 |
| HD Term Type, Inflammation | Altered Intercellular Communication | ESA responsiveness can be considered a strong prognostic factor in HD patients and seems to be tightly related to protein-energy wasting and inflammation. | 21325348 |
| Inflammation, Endothelial dysfunction | Altered Intercellular Communication | Selected dietary flavonoids are associated with markers of inflammation and endothelial dysfunction in U.S. women. | 21325476 |
| Inflammation, Metabolic Syndrome X, Cardiovascular Diseases, Atherosclerosis, Diabetes Mellitus, Non-Insulin-Dependent | Altered Intercellular Communication | Dietary pattern may influence the risks of cardiovascular disease, atherosclerosis, type 2 diabetes, and metabolic syndrome through its effects on inflammation. | 21325731 |
| Liver carcinoma, Hypercalcemia, CTCAE | Altered Intercellular Communication | Severe hypercalcemia associated with hepatocellular carcinoma secreting intact parathyroid hormone: a case report. | 21325766 |
| Inflammation | Altered Intercellular Communication | Hypovitaminosis D is associated with systemic inflammation and concentric myocardial geometric pattern in hemodialysis patients with low iPTH levels. | 21325871 |
| HD Term Type, Hyperparathyroidism, Inflammation | Altered Intercellular Communication | The aim of this study was to identify hypovitaminosis D in HD patients without signs of hyperparathyroidism and to analyze its association to inflammation and echocardiographic alterations. | 21325871 |
| Inflammation | Altered Intercellular Communication | Hypovitaminosis D is associated with inflammation and concentric geometric pattern of the left ventricle, even in the absence of high iPTH levels. | 21325871 |
| Airway structure | Altered Intercellular Communication | In a model of airway inflammation healthy volunteers inhaled 20 mg of lipopolysaccharide (LPS), which resulted in an increase of small sputum macrophages from 18% +- 19% to 64% +- 25%. | 21327296 |
| Lymphoma | Altered Intercellular Communication | This suggests that the presence of chronic inflammatory conditions does not decisively influence the outcome of lymphoma patients. | 21327940 |
| Inflammation, Diabetes Mellitus, Non-Insulin-Dependent | Altered Intercellular Communication | Type 2 diabetes is a manifestation of an ongoing low-grade inflammation. | 21327984 |
| Inflammation, Diabetes Mellitus, Impaired | Altered Intercellular Communication | In diabetes, impairment of neutrophil adhesion to the endothelium and migration to the site of inflammation were detected, which associated closely with adhesion molecules expressed on neutrophils and endothelial cells. | 21327984 |
| Inflammation, Familial Mediterranean Fever, Pulmonary Embolism | Altered Intercellular Communication | We identified untreated FMF and chronic inflammation as his only risk factor for pulmonary embolism. | 21329287 |
| Inflammation, Familial Mediterranean Fever | Altered Intercellular Communication | With this case report, we support recent studies that have demonstrated that inflammation may lead to prothrombotic states in patients with FMF. | 21329287 |
| Inflammation | Altered Intercellular Communication | Nuclear factor-kappa B (NF-kB) signalling plays an important role in gene regulation and is implicated in inflammation, oxidative stress and apoptosis. | 21329555 |
| Kidney Failure, Chronic, Inflammation | Altered Intercellular Communication | Besides regulating energy metabolism, leptin promotes and adiponectin suppresses inflammation which is a common feature of end-stage renal disease (ESRD). | 21329629 |
| Periodontal Diseases, atherosclerotic | Altered Intercellular Communication | These findings provide direct evidence for an association between periodontal disease and atherosclerotic inflammation. | 21329844 |
| Inflammation, Metabolic Diseases | Altered Intercellular Communication | Such association may be linked to the baseline mechanisms related to metabolic disorder (adiponectin) and systemic inflammation (hsCRP). | 21330312 |
| Inflammation, Hypertension, CTCAE, Cardiovascular Diseases | Altered Intercellular Communication | Elevated neutrophil count, a marker of systemic inflammation, has been suggested as a prognostic marker of cardiovascular disease in postmenopausal women with hypertension. | 21331053 |
| Inflammation, Obesity | Altered Intercellular Communication | Circulating oxidized LDL and inflammation in extreme pediatric obesity. | 21331062 |
| Inflammation, Obesity | Altered Intercellular Communication | Oxidative stress and inflammation have not been well-characterized in extreme pediatric obesity. | 21331062 |
| Inflammation, Diabetes Mellitus, Non-Insulin-Dependent, Obesity, Cardiovascular Diseases | Altered Intercellular Communication | Extreme pediatric obesity, compared to milder forms of adiposity and NW, is associated with higher levels of oxidative stress and inflammation, suggesting that markers of early cardiovascular disease and type 2 diabetes mellitus are already present in this young population. | 21331062 |
| Inflammation, Nasal Polyps | Altered Intercellular Communication | Final histopathology of the remaining 23 patients was consistent with inflammation and/or nasal polyposis. | 21331779 |
| Inflammation, Anemia | Altered Intercellular Communication | However, their relation to nutrition, anemia, and micro inflammation is not well characterized. | 21332333 |
| Inflammation, Fibrosis Assessment, Diabetes Mellitus | Altered Intercellular Communication | In multivariate analysis, older age was associated with severe (Brunt >= 2) inflammation (odds ratio [OR] 1.1, P = 0.002) and severe (Brunt >= 3) fibrosis (OR 1.2, P = 0.001), diabetes was associated with severe inflammation (OR 3.18, P = 0.07) and severe fibrosis (OR 8.81, P = 0.002), and increased BMI was associated with severe fibrosis (OR 2.43, P = 0.07). | 21332546 |
| Inflammation, Fatty degeneration | Altered Intercellular Communication | Additionally, compared to Caucasians, Asian-Americans showed a trend toward an association with severe (Brunt > 2) steatosis (OR 3.83, P = 0.08) and severe inflammation (OR 5.42, P = 0.06). | 21332546 |
| Inflammation | Altered Intercellular Communication | The lesion was treated preoperatively with a potent topical corticosteroid resulting in a reduction of inflammation. | 21332699 |
| Inflammation, PLAU protein, human | Altered Intercellular Communication | Urokinase-type plasminogen activator receptor (uPAR) is expressed on a variety of different immune cells and vascular endothelial cells during inflammation. | 21332843 |
| Inflammation | Altered Intercellular Communication | Postoperative complications included 2 graft rejection episodes in 2 patients during the first year after surgery, 1 case of increased inflammation that required removal of the IOL, and 2 cases of new-onset glaucoma. | 21333880 |
| Glaucoma, CTCAE, Acute inflammation | Altered Intercellular Communication | Graft rejection, glaucoma, and postoperative inflammation are possible complications. | 21333880 |
| Inflammation, Chronic heart failure, Heart failure | Altered Intercellular Communication | In our previous study we have shown that inflammation was able to induce increased NT pro BNP in a hospital cohort with chronic heart failure in the elderly, indicating that NT-proBNP/BNP ratio should be evaluated concomitantly with inflammatory status to avoid overestimation of heart failure severity. | 21334085 |
| Inflammation, Erectile dysfunction | Altered Intercellular Communication | Previous data suggest a potential relationship between inflammation and erectile dysfunction. | 21334642 |
| Communicable Diseases, Inflammation | Altered Intercellular Communication | As organisms age the vulnerability to illnesses such as infection and inflammation increases and late complications due to infectious agents are mostly observed in the older part of the population. | 21334752 |
| Inflammation | Altered Intercellular Communication | Our results indicate a significant increase in Hsp70 serum levels with increasing degree of inflammation. | 21334752 |
| Inflammation, Observation Method - Coagulation | Altered Intercellular Communication | (r) being observed, surrogate markers of coagulation and inflammation seem to be less pronounced in patients where cardiotomy blood is not being directly reinfused. | 21334912 |
| Inflammation, Heart failure | Altered Intercellular Communication | The abundance of a preselection of transcripts involved in inflammation, immunosenescence and stress response was compared between PBMC of healthy aged donors and aged patients in acute phase of heart failure and at recovery. | 21335025 |
| Inflammation | Altered Intercellular Communication | Transcripts involved in inflammation and oxidative stress were more abundant. | 21335025 |
| Carcinoma of lung, Pneumonitis, Tuberculosis | Altered Intercellular Communication | Tuberculosis may increase lung cancer risk through substantial and prolonged pulmonary inflammation. | 21335509 |
| Inflammation, Carcinoma of lung, Lung | Altered Intercellular Communication | Our results add to the growing body of evidence implicating chronic inflammation and pulmonary scarring in the etiology of lung cancer. | 21335509 |
| methyldopa, Inflammation, Disease | Altered Intercellular Communication | Based on the obtained results, it may be concluded that lipid status disorder and inflammation could play an important role in the development of AMD in elderly people. | 21336002 |
| Degenerative polyarthritis, Inflammation | Altered Intercellular Communication | Mediators of inflammation are the potential predicting factors of OA, however, with respect to examined chemokines development of a diagnostic test can be limited by the low serum concentration and lack of correlation with clinical and radiological signs of the disease. | 21336628 |
| Inflammation, Primary malignant neoplasm, Obesity | Altered Intercellular Communication | Obesity is characterized by chronic mild inflammation and may influence the risk and progression of cancer. | 21336679 |
| Sjogrens Syndrome", Inflammation, Sicca Syndrome | Altered Intercellular Communication | Whole stimulated salivary flow: correlation with the pathology of inflammation and damage in minor salivary gland biopsy specimens from patients with primary Sjogren's syndrome but not patients with sicca. | 21337320 |
| Inflammation, Fibrosis Assessment | Altered Intercellular Communication | Compared with unstimulated salivary flow, stimulated salivary flow appeared to be a better measure of inflammation (according to the focus score) and fibrosis. | 21337320 |
| Inflammation, Fibrosis Assessment | Altered Intercellular Communication | In the future, stimulated salivary flow may serve as a noninvasive surrogate biomarker of inflammation and fibrosis as well as a measure of response to treatment in patients with primary SS. | 21337320 |
| Acute inflammation | Altered Intercellular Communication | Computed tomographic enterography (CTE) has been shown to have a high sensitivity and specificity for active small bowel inflammation. | 21337477 |
| Enteritis | Altered Intercellular Communication | CTE is a clinically useful examination, altering management plans in nearly half of patients with CD, while increasing physician LOC for the detection of small bowel inflammation and penetrating disease. | 21337477 |
| Arthritis, Inflammatory polyarthritis | Altered Intercellular Communication | Reduction of long-term disability in inflammatory polyarthritis by early and persistent suppression of joint inflammation: results from the Norfolk Arthritis Register. | 21337726 |
| Inflammation | Altered Intercellular Communication | Remission was defined as the absence of clinically detectable joint inflammation on a 51-joint count. | 21337726 |
| Airway structure | Altered Intercellular Communication | Fraction of exhaled nitric oxide (FeNO) as a biomarker of airway inflammation in children warrants better clarification. | 21338427 |
| Ischemia, Inflammation, Brain Injuries, Neoplasms | Altered Intercellular Communication | Nestin expression has also been detected under such pathological conditions as ischemia, inflammation, and brain injury, as well as in various types of human solid tumors and their corresponding cell lines. | 21340483 |
| Anejaculation, Epilepsy | Altered Intercellular Communication | We report a case of ejaculation failure and abnormal hormonal profile in a patient affected by epilepsy. | 21341560 |
| Inflammation, Crypt | Altered Intercellular Communication | Resection margins revealed no significant difference in crypt distortion, depletion of mucin, acute inflammation, chronic inflammation and infiltration of eosinophils following NAT compared with controls. | 21341624 |
| Degenerative polyarthritis, Inflammation | Altered Intercellular Communication | Cartilage oligomeric matrix protein - inflammation biomarker in knee osteoarthritis. | 21342138 |
| Inflammation, effusion, Idiopathic osteoarthritis, Synovitis | Altered Intercellular Communication | The aim of this study was to analyze and compare ultrasound parameters of joint inflammation, effusion and synovitis with the levels of COMP in the serum of patients with primary osteoarthritis. | 21342138 |
| Coughing, Chronic cough, Airway structure, Gastroesophageal reflux disease | Altered Intercellular Communication | Cough reflex sensitivity and airway inflammation in patients with chronic cough due to non-acid gastro-oesophageal reflux. | 21342332 |
| Neurogenic Inflammation, Coughing, Chronic cough, Gastroesophageal reflux disease, Hypersensitivity | Altered Intercellular Communication | Chronic cough due to non-acid reflux may be related to cough reflex hypersensitivity caused by neurogenic airway inflammation and mast cell activation, in which weakly acidic reflux is possibly a major factor. | 21342332 |
| Gastrointestinal inflammation | Altered Intercellular Communication | A new tachykinin, hemokinin (HK-1), has been identified in non-neuronal cells in recent years and its role in intestinal inflammation is unclear. | 21342363 |
| Inflammation | Altered Intercellular Communication | Inflammation lesions in kidney transplant biopsies: association with survival is due to the underlying diseases. | 21342447 |
| Inflammation, Tubulitis Assessment, Intimal Arteritis Assessment | Altered Intercellular Communication | We used a modified Banff classification, separately assessing inflammation (i-) in nonscarred (i-Banff), scarred (i-IFTA) and whole cortex (i-total), plus tubulitis and intimal arteritis. | 21342447 |
| Inflammation | Altered Intercellular Communication | In multivariate analysis, outcome was better predicted by the presence of progressive disease than by inflammation. | 21342447 |
| Inflammation | Altered Intercellular Communication | Thus inflammation in late kidney transplants has no inherent prognostic impact, but predicts reduced survival because inflammation indicates actively progressing diseases. | 21342447 |
| Inflammation, vinyltriethoxysilane | Altered Intercellular Communication | Blood markers of haemostasis and inflammation are not strongly predictive of VTE in older age however BMI, country and lower systolic blood pressure are independently associated with VTE risk. | 21342490 |
| ARCN1 gene, Inflammation, Chronic Obstructive Airway Disease, Herpes zoster disease | Altered Intercellular Communication | Background Systemic inflammation and dysregulated immune function in chronic obstructive pulmonary disease (COPD) is hypothesized to predispose patients to development of herpes zoster. | 21343261 |
| Hypogonadism, Failure, Klinefelter Syndrome | Altered Intercellular Communication | Twelve patients were eugonadic (normal LH, T, and FSH), while 18 displayed hormonal evidence of hypogonadism, characterized by tubular failure (increased FSH) in all the subjects and associated with interstitial failure in 14 subjects: seven with primary hypogonadism (increased LH and reduced T) and seven with compensated hypogonadism (increased LH and normal T). | 21344196 |
| allergic inflammation | Altered Intercellular Communication | Furthermore, local nasal IgE directed against these exotoxins may create a local allergic inflammation in the lateral wall of the nose. | 21344448 |
| Inflammation, Lemierre Syndrome, Thrombophlebitis, Phylum Fusobacteria | Altered Intercellular Communication | Here, we discuss a case of Lemierre syndrome in a 22-year-old man with thrombophlebitis of the facial vein and fusobacteria growth in the blood culture but no obvious focus of inflammation. | 21345516 |
| Inflammation | Altered Intercellular Communication | Furthermore, the dissociation of NfH(SMI35) levels with biomarkers of inflammation suggests that the mechanisms responsible for their production are at least partly independent. | 21346223 |
| Inflammation, Specimen Type - Fistula, Horseshoe | Altered Intercellular Communication | For all sequences, there was statistically significant agreement between readers for fistula classification, internal opening location, and the presence of sinus tracts, abscess, a horseshoe component, and inflammation. | 21348010 |
| Inflammation, Comorbidity | Altered Intercellular Communication | Comorbidity, inflammation status, race, age, and mesothelial cell mass are some factors correlated with the baseline dialysate-to-plasma ratio of creatinine. | 21348373 |
| Inflammation, Malnutrition, Atherosclerosis | Altered Intercellular Communication | Bowel bacterial overgrowth as another cause of malnutrition, inflammation, and atherosclerosis syndrome in peritoneal dialysis patients. | 21348395 |
| Inflammation, Malnutrition, Atherosclerosis | Altered Intercellular Communication | We explored the association between GL function, BBOS, and the malnutrition, inflammation, and atherosclerosis (MIA) syndrome. | 21348395 |
| Inflammation, Malnutrition, Communicable Diseases, Abnormal digestive tract function, Malabsorption Syndrome | Altered Intercellular Communication | The BBOS infectious process is found frequently in dialysis patients in association with GI malabsorption and maldigestion, malnutrition, and systemic inflammation. | 21348395 |
| Inflammation, Extracellular Matrix | Altered Intercellular Communication | In rare cases, skin metastases can manifest as lesions with signs of inflammation and are diagnosed as inflammatory cutaneous metastases (ICM). | 21348413 |
| Burn Specimen Source Codes, Inflammation | Altered Intercellular Communication | Microfluidics for T- lymphocyte cell separation and inflammation monitoring in burn patients. | 21348958 |
| Uveomeningoencephalitic Syndrome, Panuveitis, Choroiditis, Tuberculosis, Endophthalmitis, Orbital Pseudotumor | Altered Intercellular Communication | Multifocal choroiditis and panuveitis were the diagnosis in seven, ampiginous choroiditis in two, and for six remaining, serpiginous choroiditis, sympathetic ophthalmia, Vogt-Koyanagi-Harada syndrome, punctuate inner choroidopathy, tuberculosis and idiopathic inflammation. | 21348964 |
| Intraocular inflammation | Altered Intercellular Communication | Intraocular inflammation was strictly controlled in all cases by the time of injections. | 21348964 |
| Cataract, Inflammation, Uveomeningoencephalitic Syndrome | Altered Intercellular Communication | Recurrent inflammation is a critical poor prognostic factor for cataract surgery in VKH, but with appropriate management, good visual outcomes can be achieved. | 21349937 |
| Orbital Pseudotumor | Altered Intercellular Communication | Treatment of severe idiopathic orbital inflammation with intravenous methylprednisolone. | 21349945 |
| Inflammation, Chronic Kidney Diseases | Altered Intercellular Communication | Circulating follistatin in patients with chronic kidney disease: implications for muscle strength, bone mineral density, inflammation, and survival. | 21350111 |
| Inflammation, Cachexia | Altered Intercellular Communication | However, increased follistatin levels occurred together with increased inflammation, reduced muscle strength, and low BMD, suggesting an involvement of a mechanism including follistatin in the uremic wasting process. | 21350111 |
| Inflammation, Metabolic Syndrome X | Altered Intercellular Communication | Sex differences in age trajectories of physiological dysregulation: inflammation, metabolic syndrome, and allostatic load. | 21350248 |
| Inflammation, Spinal Fractures | Altered Intercellular Communication | Optimal control of inflammation may be an effective means to protect against vertebral fractures. | 21350894 |
| Degenerative polyarthritis, Damage | Altered Intercellular Communication | Matrix metalloproteinases (MMP)-13, the major type II collagen-degrading collagenase, is regulated by stress-, inflammation-, and differentiation-induced signals that not only contribute to irreversible joint damage (progression) in OA, but importantly, also to the initiation/onset phase, wherein chondrocytes in articular cartilage leave their natural growth- and differentiation-arrested state. | 21351054 |
| Inflammation, Colorectal Carcinoma, Neoplasms | Altered Intercellular Communication | Chronic inflammation is an established risk factor for colorectal cancer (CRC), and polymorphisms in genes regulating inflammatory processes appear to alter the risk for neoplasia and the efficacy of nonsteroidal anti-inflammatory drugs in CRC chemoprevention. | 21351261 |
| Inflammation, Colorectal Carcinoma | Altered Intercellular Communication | We examined the association between selected inflammation gene polymorphisms and CRC risk. | 21351261 |
| Inflammation, Squamous cell carcinoma, Neoplasms | Altered Intercellular Communication | Tumour infiltrating CD25+ FoxP3+ regulatory T cells (Tregs) relate to tumour grade and stromal inflammation in oral squamous cell carcinoma. | 21352381 |
| Cessation of life, Inflammation, Aortic Aneurysm, Abdominal | Altered Intercellular Communication | Abdominal aortic aneurysm is associated with inflammation and is a common cause of illness and death among European populations. | 21352499 |
| Inflammation | Altered Intercellular Communication | The soluble urokinase plasminogen activator receptor (suPAR) is a plasma marker of low grade inflammation and has been associated with cardiovascular risk. | 21354571 |
| Inflammation, Osteochondritis Dissecans | Altered Intercellular Communication | However, increasing evidence suggests that central and systemic inflammation triggered by surgery likely plays a fundamental role in POCD developing and progression. | 21354710 |
| Inflammation, Osteochondritis Dissecans, Impaired cognition | Altered Intercellular Communication | Considering that inflammation may be a potential factor of POCD and minocycline is effective in improving cognitive dysfunction induced by inflammation, we hypothesize that minocycline may be useful to treat/prevent the POCD development after surgery in elderly patients. | 21354710 |
| Inflammation, Sleep Apnea, Obstructive | Altered Intercellular Communication | Our study suggests that inflammation associated with OSAS might contribute to atrial structural and electrical remodeling in OSAS patients with PAC. | 21354892 |
| Gingivitis | Altered Intercellular Communication | Sixty-four consecutive volunteers presenting with gingival inflammation were recruited at their semi-annual recall appointments for this study. | 21356022 |
| Inflammation, Cerebrovascular accident | Altered Intercellular Communication | Brain inflammation is induced by co-morbidities and risk factors for stroke. | 21356305 |
| Inflammation, Atherosclerosis, Diabetes Mellitus, Cerebrovascular accident, Obesity | Altered Intercellular Communication | Chronic systemic inflammatory conditions, such as atherosclerosis, diabetes and obesity are associated with increased risk of stroke, which suggests that systemic inflammation may contribute to the development of stroke in humans. | 21356305 |
| Inflammation | Altered Intercellular Communication | First, we assessed inflammatory changes in the brain in rodent models of chronic, systemic inflammation. | 21356305 |
| Inflammation, Cerebrovascular accident | Altered Intercellular Communication | These findings show that brain inflammation occurs in animals, and tentatively in humans, harbouring risk factors for stroke associated with elevated systemic inflammation. | 21356305 |
| Inflammation, Atherosclerosis, Diabetes Mellitus, Cerebrovascular accident, Obesity | Altered Intercellular Communication | Chronic systemic inflammatory conditions, such as atherosclerosis, diabetes and obesity are associated with increased risk of stroke, which suggests that systemic inflammation may contribute to the development of stroke in humans. | 21356305 |
| Liver damage, Hepatic inflammation, Cholestasis, Intrahepatic bile duct | Altered Intercellular Communication | The results suggest that in this model of chronic cholestasis, fibrin constrains the release of bile constituents from injured intrahepatic bile ducts, thereby limiting the progression of hepatic inflammation and hepatocellular injury. | 21356363 |
| Inflammation | Altered Intercellular Communication | The relationship between AGEs, RAGE, and inflammation has not been well characterized. | 21357189 |
| Inflammation | Altered Intercellular Communication | These findings suggest that plasma esRAGE plays a role in modulating inflammation, although the exact mechanisms remain to be elucidated. | 21357189 |
| Inflammation, Pruritus | Altered Intercellular Communication | A 28-year-old man, presented with edematous and erythematous patchy lesion along with pruritus and inflammation on lip, have been suffering since 3 hours. | 21357631 |
| Nasal inflammation | Altered Intercellular Communication | Serial measurements of surrogates of nasal inflammation (such as nitric oxide or cytokine levels) were not performed. | 21357906 |
| Vasculitis | Altered Intercellular Communication | Fas and Fas Ligand have been implicated in apoptosis and vessel wall inflammation. | 21359408 |
| Plexiform ameloblastoma, Acute inflammation | Altered Intercellular Communication | In reopening the previous marsupialization, a new biopsy was performed with histopathologic findings compatible with plexiform ameloblastoma associated with acute inflammation. | 21360116 |
| Depression, CTCAE | Altered Intercellular Communication | Association between depression and malnutrition-inflammation complex syndrome in patients with continuous ambulatory peritoneal dialysis. | 21360161 |
| Depression, CTCAE | Altered Intercellular Communication | The prevalence of depression and its relation with the malnutrition-inflammation complex syndrome (MICS) have not yet been clearly defined in Chinese continuous ambulatory peritoneal dialysis (CAPD) patients. | 21360161 |
| Depression, CTCAE | Altered Intercellular Communication | The Hamilton Depression Scale (HAMD) and the malnutrition-inflammation score (MIS) were used for depression and MICS evaluation, respectively. | 21360161 |
| Depression, CTCAE | Altered Intercellular Communication | Clinical, socioeconomic, and malnutrition-inflammation factors were compared among patients with and without depression. | 21360161 |
| hearing impairment, Inflammation, NLRP3 gene | Altered Intercellular Communication | Organ manifestations of MWS improved, as did all patient-derived measures of health status, markers of inflammation, and hearing loss in 2 of the patients. | 21360513 |
| Rupture, Granulomatous inflammation | Altered Intercellular Communication | Parietal rupture was present, accompanied by granulomatous inflammation. | 21361125 |
| Inflammation, Ankylosis | Altered Intercellular Communication | No signs of inflammation, root resorption, ankylosis, mobility, sensitivity, pocket problems, or pulp destructions were found after 2-year follow up. | 21361776 |
| Inflammation | Altered Intercellular Communication | Inflammation with focal and/or diffuse concentration of round cells was detected in the SN in 22 cases (44%). | 21361943 |
| Inflammation, Early-onset, diabetic | Altered Intercellular Communication | The homozygous CC genotype of rs1333049 confers a magnified risk of early-onset and more severe CAD in diabetic patients through a novel biological pathway unrelated to glucose metabolism or inflammation. | 21362310 |
| Degenerative polyarthritis, Inflammation, LPCAT3 gene | Altered Intercellular Communication | The authors detected four unexpected biomarkers (V65 vitronectin fragment, C3f peptide, CTAP-III and m/z 3762 protein) that could be relevant in the pathophysiological process of OA as having significant correlation with parameters reflecting local inflammation and bone remodelling, as well as decrease in cartilage turnover. | 21362709 |
| Inflammation, Rheumatoid Arthritis, Erosion of bone | Altered Intercellular Communication | Circulating Dickkopf-1 is correlated with bone erosion and inflammation in rheumatoid arthritis. | 21362762 |
| Refractory anemias, Inflammation, Erosion of bone | Altered Intercellular Communication | DKK-1, as an important mediator, was correlated with bone erosion and inflammation in RA. | 21362762 |
| Ulcerative Colitis-Associated Colorectal Adenocarcinoma, Inflammation | Altered Intercellular Communication | Ulcerative colitis-associated colorectal cancer arises in a field of short telomeres, senescence, and inflammation. | 21363920 |
| Inflammation, Primary malignant neoplasm | Altered Intercellular Communication | Inflammation plays a role in the progression to cancer and it is linked to the presence of senescent cells. | 21363920 |
| Inflammation, Neoplasms, Ulcerative Colitis | Altered Intercellular Communication | We hypothesized that a preneoplastic field of inflammation, telomere shortening, and senescence underlies tumor progression in UC progressors. | 21363920 |
| Inflammation, Ulcerative Colitis | Altered Intercellular Communication | Multiple biopsies of varying histologic grade were collected along the colon of nine UC progressors and analyzed for telomere length, DNA damage, senescence, p53, p16, and chronic and acute inflammation. | 21363920 |
| Inflammation, Dysplasia | Altered Intercellular Communication | These results suggest that dysplasia arises in a preneoplastic field of chronic inflammation, which leads to telomere shortening, DNA damage, and senescence. | 21363920 |
| Inflammation | Altered Intercellular Communication | Elevated inflammation has been associated with a number of poor health outcomes. | 21364200 |
| Inflammation, Bipolar Disorder | Altered Intercellular Communication | Participation in moderate-intensity physical activity may buffer the risk of higher inflammation often associated with higher levels of depressive symptoms. | 21364200 |
| Centrilobular Opacity | Altered Intercellular Communication | Extra-fine particle inhaled corticosteroids could be an alternative approach in centrilobular opacities caused by eosinophilic peripheral airway inflammation. | 21364311 |
| Neoplasms | Altered Intercellular Communication | Because of its proximity to the teeth and periodontium, the tumor can mimic tooth-related benign inflammatory conditions. | 21365032 |
| Inflammation | Altered Intercellular Communication | This allows a substantially increased bacterial uptake, which may contribute to recurrence of inflammation. | 21366635 |
| Infection, atherosclerotic, Cardiovascular Diseases | Altered Intercellular Communication | Our results suggest revisiting the hypothesis that infections may have a causative role in atherosclerotic inflammation and have implications for research regarding novel diagnostics and treatments for cardiovascular disease. | 21366733 |
| Coma (genus), Inflammation, Cerebral dysfunction, Sepsis, Delirium | Altered Intercellular Communication | In our pilot study, high baseline inflammatory biomarkers predicted prolonged periods of acute brain dysfunction, implicating inflammation as an important mechanism in the pathophysiology of delirium and coma during critical illness, irrespective of whether patients had sepsis or not. | 21366899 |
| Inflammation, Edema of lower extremity, Venous Insufficiency | Altered Intercellular Communication | No pharmacological treatment exists for lower extremity pitting edema, characterized by inflammation, found in chronic venous insufficiency. | 21366964 |
| Inflammation, Hypertriglyceridemia, Metabolic Syndrome X | Altered Intercellular Communication | Metabolic syndrome components, such as increased waist circumference, hypertriglyceridaemia and smoking, were inversely associated with RHI as were serum markers of inflammation. | 21367423 |
| Papilledema, Retinitis, Edema, Uveitis, Vitritis, Conjunctivitis, Keratoconjunctivitis | Altered Intercellular Communication | With their ability to migrate into the cornea and release toxins, caterpillar hairs can induce different clinical presentations such as conjunctivitis, keratoconjunctivitis, uveitis, and less frequently vitreoretinal inflammation (hyalitis, papillitis, macular edema). | 21367484 |
| ARCN1 gene, Inflammation, Comorbidity, Data Type -Character | Altered Intercellular Communication | COPD is characterized by a multi-component character involving a state of low-grade systemic inflammation and an increased prevalence of cardiovascular co-morbidity. | 21367591 |
| ARCN1 gene, Inflammation | Altered Intercellular Communication | The role of circulating leptin and other adipokines in the involvement of the systemic inflammation in COPD is only studied scarcely. | 21367591 |
| Inflammation, Primary malignant neoplasm | Altered Intercellular Communication | The results support the hypothesis that chronic inflammation plays a role in cancer. | 21368452 |
| Autoimmune Diseases, Inflammation, Primary malignant neoplasm | Altered Intercellular Communication | Recently, a subset of IL-17 producing T cells distinct from Th1 or Th2 cells has been described as key players in inflammation and autoimmune diseases as well as cancer development. | 21369705 |
| Allergic, Inflammation | Altered Intercellular Communication | Leukotrienes, especially LTC4, are important inflammatory mediators in allergic and nonallergic inflammation of the entire airways. | 21370724 |
| Nasal Polyps, Asthma, Eosinophilic inflammation | Altered Intercellular Communication | Leukotriene 1 receptor blockade led to a significant decrease in eosinophil inflammation accompanied by a reduction in other mediators such as neurokinin A and substance P in the nasal lavage fluid of patients with nasal polyps and asthma, with or without aspirin intolerance. | 21370724 |
| Inflammation, Chronic sinusitis, Craniosynostosis | Altered Intercellular Communication | The prevalence of CRSwNP with pronounced eosinophilic inflammation is steadily increasing and is classified as eosinophilic chronic rhinosinusitis (ECRS) in Japan. | 21371840 |
| PDR gene, Acute inflammation | Altered Intercellular Communication | This was associated with a significantly higher postoperative inflammation and IOP in PDR group. | 21372484 |
| Acute inflammation, diabetic | Altered Intercellular Communication | The higher postoperative inflammation and IOP following vitrectomy in diabetic eyes, especially when combined with endolaser photocoagulation, makes such eyes less susceptible to wound sealing-related complications following sutureless vitrectomy. | 21372484 |
| Cell Death, vascular inflammations, Diabetic Retinopathy | Altered Intercellular Communication | Cannabinoid 1 receptor activation contributes to vascular inflammation and cell death in a mouse model of diabetic retinopathy and a human retinal cell line. | 21373835 |
| Inflammation, Cardiomyopathies, Atherosclerosis, Cardiac dysfunction, Kidney Diseases, Cessation of life | Altered Intercellular Communication | Recent studies have demonstrated that cannabinoid-1 (CB(1)) receptor blockade ameliorated inflammation, endothelial and/or cardiac dysfunction, and cell death in models of nephropathy, atherosclerosis and cardiomyopathy. | 21373835 |
| Diabetic Retinopathy | Altered Intercellular Communication | Activation of CB(1) receptors may play an important role in the pathogenesis of diabetic retinopathy by facilitating MAPK activation, oxidative stress and inflammatory signalling. | 21373835 |
| Fibrosis Assessment | Altered Intercellular Communication | Green tea polyphenols avert chronic inflammation-induced myocardial fibrosis of female rats. | 21373880 |
| Fibrosis Assessment | Altered Intercellular Communication | Green tea proposes anti-inflammatory properties which may attenuate chronic inflammation-induced fibrosis of vessels. | 21373880 |
| Fibrosis Assessment, Chronic inflammation | Altered Intercellular Communication | This study evaluated whether green tea polyphenols (GTP) can avert fibrosis or vascular disruption along with mechanisms in rats with chronic inflammation. | 21373880 |
| Inflammation, Fibrosis Assessment | Altered Intercellular Communication | GTP attenuates myocardial fibrosis through a suppression of chronic inflammation and innate immune responses. | 21373880 |
| Inflammation, Non-Small Cell Lung Carcinoma | Altered Intercellular Communication | NSCLC arises in the complex environment of chronic inflammation. | 21373990 |
| Amblyopia, Intraocular inflammation, Disease remission, Unspecified visual loss | Altered Intercellular Communication | Of eyes with active disease, the main contributors to vision loss at presentation were intraocular inflammation (74.8%) and macular involvement (24.3%), whereas in eyes with inactive lesions the main contributors to vision loss were macular scar formation (67.9%) and amblyopia (11.3%). | 21374556 |
| Amblyopia, Inflammation | Altered Intercellular Communication | The most common contributors to decreased vision in eyes with active lesions were inflammation and macular involvement, whereas in eyes with inactive lesions they were macular scar formation and amblyopia. | 21374556 |
| Inflammation | Altered Intercellular Communication | Regulation of VEGF expression in human retinal cells by cytokines: implications for the role of inflammation in age-related macular degeneration. | 21374591 |
| methyldopa, Inflammation, Age related macular degeneration | Altered Intercellular Communication | Chronic inflammation is implicated in the pathogenesis of age-related macular degeneration (AMD). | 21374591 |
| Inflammation, Atopy | Altered Intercellular Communication | Imbalance of Th17/Treg has been considered critical in the development of inflammation and atopic reactions. | 21375554 |
| Tuberculosis, Acute and chronic inflammation, Septicemia, Takayasu Arteritis | Altered Intercellular Communication | Chronic infective and inflammatory conditions included tuberculosis (n = 4), HIV (n = 3), staphylococcal septicemia (n = 2), and Takayasu arteritis (n = 1). | 21376188 |
| Inflammation, Rhinosinusitis, Nasal Polyps | Altered Intercellular Communication | Our result demonstrated strong evidence that diffuse mucosal inflammation and active cellular proliferation do exist in rhinosinusitis with nasal polyposis. | 21377232 |
| Airway structure | Altered Intercellular Communication | There was no relationship between EBC pH and disease severity, as assessed by the percent predicted FEV(1), nor with airway inflammation as assessed by sputum leukocyte counts. | 21377342 |
| ARCN1 gene, Airway structure | Altered Intercellular Communication | EBC pH is lower in COPD than in healthy control non-smokers, but does not differentiate COPD from smokers without COPD, relate to disease severity or to airway inflammation, and does not respond to corticosteroids. | 21377342 |
| Inflammation, Diabetes Mellitus, Non-Insulin-Dependent | Altered Intercellular Communication | TLR4 and RAGE: similar routes leading to inflammation in type 2 diabetic patients. | 21377387 |
| Inflammation, Aortic Aneurysm, Aneurysm, Ruptured, Atherosclerosis | Altered Intercellular Communication | Tight, diffuse pleural adhesion and the vulnerable wall of an aortic aneurysm due to advanced atherosclerosis with active inflammation appeared to have predominantly contributed to the penetration of the ruptured aneurysm into the lung. | 21377396 |
| Inflammation, Renal function | Altered Intercellular Communication | Vascular health, systemic inflammation and progressive reduction in kidney function; clinical determinants and impact on cardiovascular outcomes. | 21378154 |
| Inflammation, Endothelial dysfunction | Altered Intercellular Communication | Systemic inflammation, endothelial dysfunction and arterial thickening contribute to the elevated cardiovascular risk of dialysis patients. | 21378154 |
| Inflammation, Endothelial dysfunction, Thickened | Altered Intercellular Communication | Endothelial dysfunction, arterial thickening and inflammation occur in parallel with the decline in eGFR, contributing to the increased cardiovascular risk of nondialysed CKD. | 21378154 |
| Inflammation, Chronic Kidney Diseases | Altered Intercellular Communication | Thiazolidinediones such as rosiglitazone (RSG) are insulin-sensitizing agents, which may improve inflammation and vascular function, and thus potentially lower cardiovascular risk in patients with chronic kidney disease (CKD). | 21378155 |
| Cytomegalovirus Infections, Inflammation | Altered Intercellular Communication | Future work should target the mechanisms by which CMV infection and low-level inflammation interact to yield significant impact on mortality. | 21379581 |
| MPP1 wt Allele | Altered Intercellular Communication | This selective pressure becomes more relaxed in the adult organism, permitting the onset of aging-associated diseases and inflammation-related aging; this concept echoes the antagonistic pleiotropy hypothesis of aging. | 21380541 |
| Inflammation, Ulcer | Altered Intercellular Communication | Biopsies from the ulcers showed only non-specific inflammation. | 21380762 |
| Inflammation | Altered Intercellular Communication | Endogenous opioid peptides have been shown to play a role in the development and/or perpetuation of inflammation. | 21380937 |
| Inflammatory Bowel Diseases, Inflammation | Altered Intercellular Communication | We hypothesize that the endogenous opioid system is involved in inflammatory bowel disease, and antagonism of the opioid-opioid receptor will lead to reversal of inflammation. | 21380937 |
| Inflammation, Carcinogenesis | Altered Intercellular Communication | These findings support the importance of localized inflammation in alimentary tract carcinogenesis. | 21381009 |
| Inflammation, Obesity, Visceral | Altered Intercellular Communication | Visceral obesity and inflammation markers in relation to serum prostate volume biomarkers among apparently healthy men. | 21382022 |
| Inflammation, Dental Plaque, Osteopenia | Altered Intercellular Communication | Forty-two implants were assessed for implant survival, marginal bone loss, surgical and/or prosthetic complications, presence or absence of plaque, signs of inflammation and size of the papilla. | 21382092 |
| Inflammation, Dental Plaque | Altered Intercellular Communication | Repeated soft-tissue examinations revealed healthy conditions in terms of 6.1% plaque and 4.2% of the implants with signs of inflammation at the 5-year control. | 21382092 |
| Inflammation | Altered Intercellular Communication | Angiotensin converting enzyme (ACE) is a regulator of renin angiotensin system (RAS) that plays an important role in the physiology of the vasculature, blood pressure, inflammation, adipocyte distribution of various diseases. | 21382792 |
| Inflammation | Altered Intercellular Communication | Electron microscopy demonstrated that inflammation was caused by Cryptococcus neoformans, which was localized exclusively within macrophages, where it grew with budding. | 21384279 |
| Inflammation, Hepatitis C | Altered Intercellular Communication | Relationship between the interleukin-28b gene polymorphism and the histological severity of hepatitis C virus-induced graft inflammation and the response to antiviral therapy after liver transplantation. | 21384511 |
| Inflammation, Fibrosis Assessment | Altered Intercellular Communication | Genetic variants of cytokines involved in the immune response may contribute to the degree of graft inflammation, fibrosis progression, and antiviral therapy outcome. | 21384511 |
| Inflammation, Fibrosis Assessment | Altered Intercellular Communication | 605 protocol liver biopsies performed 0.5 to 10 and more than 10 years after transplantation were evaluated according to Desmet and Scheuer classification of inflammation and fibrosis. | 21384511 |
| Inflammation, Rheumatoid Arthritis | Altered Intercellular Communication | Polymorphisms in genes controlling inflammation and tissue repair in rheumatoid arthritis: a case control study. | 21385363 |
| Sarcoidosis, Aspergillosis, Orbital Pseudotumor | Altered Intercellular Communication | Thirty-three patients were analysed, consisting of 15 patients with orbital WG, 11 with idiopathic orbital inflammation, 6 with orbital sarcoidosis and one with aspergillosis. | 21385547 |
| Granulomatous inflammation, orbit (eye disorders), Vasculitis, CTCAE | Altered Intercellular Communication | Diagnostic findings indicating orbital WG were ear/nose/throat involvement, multiple organ system involvement, a positive ANCA, and on histology vasculitis, whereas granulomatous inflammation without signs of vasculitis was more indicative of another orbital disease. | 21385547 |
| Orbital Melanoma | Altered Intercellular Communication | Four months after surgery, follow-up positron emission tomography/CT imaging revealed physiologic metabolic activity in the MEDPOR implant with no evidence of orbital melanoma or chronic inflammation. | 21386739 |
| Inflammation, Obesity, Metabolic Stress | Altered Intercellular Communication | In obesity, metabolic stress and inflammation in injured tissues could favour enhanced shedding of procoagulant microparticles (MPs). | 21386797 |
| Inflammation, Hyperplastic Polyp, Endothelium | Altered Intercellular Communication | In obese females, we sought to evaluate the impact of a very low-calorie diet (VLCD) on procoagulant MP levels, fibrinolytic status, inflammation and endothelium damage. | 21386797 |
| Inflammation, Blood Vessel | Altered Intercellular Communication | Circulating biomarkers of vascular damage, fibrinolytic status, platelet activation and inflammation were measured before, 30 and 90 days after starting a short-term VLCD. | 21386797 |
| Inflammation | Altered Intercellular Communication | Secretion is linked to the size and number of adipocytes, as well as to concomitant secretion of inflammatory mediators, suggesting that TRAP is involved in fat accumulation and adipose inflammation. | 21386798 |
| Lymphocytic hypopituitarism, Neuroendocrine disease or syndrome, Have Autoimmune or Inflammatory Condition | Altered Intercellular Communication | Lymphocytic hypophysitis (LYH) is a rare neuroendocrine disorder characterized by autoimmune inflammation of the pituitary gland. | 21387696 |
| Orchitis | Altered Intercellular Communication | Pathologically bony cartilage change was seen but no definite auricular inflammation findings. | 21387702 |
| Cartilage destruction, Inflammation, polychondritis, Traumatic injury | Altered Intercellular Communication | Residual auricular cartilage scarring, however, indicated cartilage destruction by previous inflammation or trauma, yielding a final diagnosis of relapsing polychondritis. | 21387702 |
| Inflammation | Altered Intercellular Communication | Perturbed expression and function of immune regulatory molecules called leukocyte immunoglobulin-like receptors (LILRs) may contribute to uncontrolled inflammation. | 21388353 |
| Inflammation | Altered Intercellular Communication | The pure medical-grade silicon implanted in miniscule amounts in a controlled manner results in minimal fibroplasia without significant inflammation. | 21388657 |
| Inflammation, Musculoskeletal Pain | Altered Intercellular Communication | Polymyalgia rheumatica (PMR) is characterized by aching proximal muscles and systemic inflammation. | 21388741 |
| Airway structure | Altered Intercellular Communication | Exhaled breath condensate (EBC) analysis is a non-invasive method to repeatedly evaluate airway inflammation. | 21389585 |
| Inflammation, Proteostasis Deficiencies, Toxic effect | Altered Intercellular Communication | Cell damage during the course of inflammation results in cytoplasmic actin release, which if not eliminated by the extracellular actin scavenger system, composed of gelsolin and vitamin D binding protein, can cause dysfunction of hemostasis and toxicity towards surrounding cells. | 21389683 |
| Inflammation, Thrombosis, Pulmonary Hypertension | Altered Intercellular Communication | Independent predictors of elevated D-dimer in CVD patients with no visible thromboses are as follows: female gender, age >68 years, acute inflammation, pulmonary hypertension, and decompensation of CCI. | 21389943 |
| Inflammation | Altered Intercellular Communication | New-generation leads present a sophisticated design with improved geometry and steroid-eluting tips to reduce chronic inflammation, maintaining a low pacing threshold and high sensing capability. | 21391322 |
| Retinal Detachment, Retinitis, Neurocysticercosis | Altered Intercellular Communication | The natural history of ocular neurocysticercosis or enhanced sub-retinal inflammation due to Albendazole therapy could have resulted in the retinal detachment in this case. | 21391379 |
| Celiac Disease, Inflammation | Altered Intercellular Communication | Coeliac disease is a chronic inflammation of the intestinal mucosa controlled by gluten-specific T cells restricted by disease-associated HLA-DQ molecules. | 21392045 |
| Colitis, Ischemic, Colitis | Altered Intercellular Communication | A computed tomography (CT) scan of the abdomen was conducted, which revealed left colonic inflammation consistent with colonic ischemia. | 21392850 |
| Inflammation, Progranulins, GRN wt Allele | Altered Intercellular Communication | The growth factor progranulin (PGRN) has been implicated in embryonic development, tissue repair, tumorigenesis, and inflammation, but its receptors remain unidentified. | 21393509 |
| Inflammation, Arthritis, GRN wt Allele | Altered Intercellular Communication | PGRN and Atsttrin prevented inflammation in multiple arthritis mouse models and inhibited TNFa-activated intracellular signaling. | 21393509 |
| Inflammation, Dental Plaque | Altered Intercellular Communication | Carotid plaque and candidate genes related to inflammation and endothelial function in Hispanics from northern Manhattan. | 21393601 |
| Inflammation, Salpingitis | Altered Intercellular Communication | Xanthogranulomatous salpingitis (XGS) is a rare form of chronic inflammation of the fallopian tubes. | 21393899 |
| Chronic salpingitis, Xanthogranulomatous inflammation, Adnexal Mass | Altered Intercellular Communication | Chronic active follicular salpingitis with xanthogranulomatous inflammation might give the impression of a cystic adnexal mass with septations on preoperative pelvic computed tomography. | 21393899 |
| Inflammation | Altered Intercellular Communication | Eye pathologic examination at autopsy showed ischemic changes, but no inflammation. | 21394060 |
| Inflammation, Hypertension, CTCAE | Altered Intercellular Communication | Ang II Upregulation of the T-lymphocyte renin-angiotensin system is amplified by low-grade inflammation in human hypertension. | 21394089 |
| Inflammation, Damage, Terminal Osseous Dysplasia and Pigmentary Defects, Hypertension, CTCAE | Altered Intercellular Communication | Low-grade inflammation facilitates the development of essential hypertension and target organ damage (TOD). | 21394089 |
| Inflammation, Terminal Osseous Dysplasia and Pigmentary Defects, Hypertension, CTCAE | Altered Intercellular Communication | In hypertension, an Ang II-driven activation of T-cell RAS, further amplified by low-grade inflammation, does occur and is associated to worse TOD. | 21394089 |
| Inflammation, Obesity | Altered Intercellular Communication | Morbid obesity is associated with a state of chronic inflammation. | 21394384 |
| Coughing, Bronchitis | Altered Intercellular Communication | From this observation we suggest that FeNO measurement should be added to the investigation of work-related cough during specific inhalation challenge, and may be considered as an alternative to induced sputum to evaluate bronchial inflammation when sputum collection is unavailable or unsuccessful. | 21394743 |
| Inflammation | Altered Intercellular Communication | These results allow us to suggest that the majority of patients with anterior eye inflammation have inflammatory changes in posterior segment. | 21394992 |
| Structure of palpebral fissure, Exophthalmos, Lagophthalmos, Orbital Pseudotumor | Altered Intercellular Communication | The following factors were found to be associated with corneal involvement in TED patients: activity of orbital inflammation, proptosis, lagophthalmos, palpebral fissure height, lower lid retraction, grade of conjunctival vital staining and low corneal sensitivity. | 21394999 |
| IL13 gene | Altered Intercellular Communication | These preliminary data show a decrease in nasal tactile sensitivity and point out interesting aspects of the nasal chronic inflammatory condition in allergic rhinitis. | 21395473 |
| Inflammation, Mucosa-Associated Lymphoid Tissue Lymphoma | Altered Intercellular Communication | Pulmonary mucosa-associated lymphoid tissue lymphoma is unique in that chronic inflammation is rare and that API2-MALT1 fusion, resulting from t(11;18)(q21;q21), occurs frequently. | 21396678 |
| Polyp of ethmoidal sinus, Inferior nasal concha | Altered Intercellular Communication | The degree of inferior turbinate inflammation correlated with that of the ipsilateral polyp of ethmoid sinus in both groups. | 21396869 |
| Nasal Polyps, Inferior nasal concha, Sinusitis, Asthma, Chronic sinusitis | Altered Intercellular Communication | The ethmoid sinus inflammation in polypoid chronic sinusitis is accompanied by a proportionate inferior turbinate inflammation, not only in the patients with asthma but also in those with isolated sinonasal polyposis. | 21396869 |
| methyldopa, Inflammation, Subretinal deposits, Family history | Altered Intercellular Communication | Given the high pathophysiological levels of bioavailable zinc present in subretinal deposits, we discuss how zinc binding to FH may contribute to deposit formation and inflammation associated with AMD. | 21396937 |
| Pain Distress Question | Altered Intercellular Communication | Inflammation relapse was associated with the coexistence of pain as presenting sign (p<0.001) and with a longer duration of symptoms prior to the initial visit (p=0.023). | 21398411 |
| Inflammatory abnormality of the eye, Ocular syphilis, Vitritis, Vasculitis, CTCAE, Anterior uveitis | Altered Intercellular Communication | Severe ocular inflammation associated with vasculitis, vitritis or anterior uveitis in ocular syphilis would appear to be a reversible phenomenon that responds well to appropriate antibiotic treatment, resulting in improvement in visual acuity. | 21398411 |
| Toxocariasis, Inflammation | Altered Intercellular Communication | The toxocariasis was unilateral in all patients, and the inflammation was acute in two-thirds of the patients. | 21400060 |
| Inflammatory, Inflammation | Altered Intercellular Communication | The clinical manifestation is unilateral and presents as acute inflammation with a peripheral inflammatory mass. | 21400060 |
| Inflammation, Microcirculation, Edema | Altered Intercellular Communication | Early CMR in TTC demonstrates a special morphological pattern of late gadolinium uptake that might correspond to localized inflammation and edema in the affected area, suggesting diffuse microcirculation damage rather than epicardial vessel involvement. | 21400545 |
| Psoriasis | Altered Intercellular Communication | Psoriasis is a chronic inflammatory condition affecting 1-3% of the population. | 21401376 |
| Refractory anemias, Rheumatoid Arthritis | Altered Intercellular Communication | Macrophage migration inhibitory factor (MIF) is one of key regulators in acute and chronic immune-inflammatory conditions including rheumatoid arthritis (RA). | 21401926 |
| Inflammation | Altered Intercellular Communication | The no-LT group had increased inflammation in the colonic mucosa at histology (p=0.011), but without visual difference at colonoscopy. | 21402617 |
| Inflammation, MS gene | Altered Intercellular Communication | Loss of braking signals during inflammation: a factor affecting the development and disease course of multiple sclerosis. | 21403007 |
| Inflammation | Altered Intercellular Communication | Defects in negative-feedback loops of inflammation lead to an overactivation of the immune system so as to predispose the brain to inflammation-sensitive MS. | 21403007 |
| Inflammation, Calcinosis, Aortic Valve Stenosis | Altered Intercellular Communication | The development of aortic valve stenosis is not only associated with calcification and extracellular matrix remodeling, but also with inflammation. | 21403093 |
| Inflammation, Liver Cirrhosis | Altered Intercellular Communication | AOPPs level positively correlated with Child-Pugh score in alcohol-related cirrhosis but not in HCV-related cirrhosis and the correlation with the indices of chronic inflammation was stronger in ALC. | 21403920 |
| Inflammation, Liver Cirrhosis | Altered Intercellular Communication | In turn, AOPPs in HCV-related cirrhosis was related to inflammation to a lesser extent, but a significant correlation with antioxidant defense could be noted. | 21403920 |
| Inflammation, Liver Cirrhosis | Altered Intercellular Communication | The significant correlation between AOPPs accumulation and indices of chronic inflammation, more specifically TNF-a, suggests that oxidative stress may be a mediator of chronic inflammatory state in the early stage of alcohol-related cirrhosis. | 21403920 |
| Inflammation, Fibrosis Assessment, Nesidioblastosis | Altered Intercellular Communication | Histologic degree of fibrosis, acinar atrophy, inflammation, and nesidioblastosis were scored by a surgical pathologist. | 21404456 |
| Inflammation, Fibrosis Assessment, Atrophic | Altered Intercellular Communication | Fibrosis and acinar atrophy correlated negatively with islet yield (P < G 0.001, r =0.67), as did inflammation (P < G 0.001, r =0.43). | 21404456 |
| palladium, Inflammation, Synovial Hypertrophy | Altered Intercellular Communication | All US examinations were performed by two rheumatologists investigating: presence of joint cavity widening (JCW), synovial fluid and/or synovial hypertrophy, peritenon extensor tendon inflammation (PTI) and intra-articular or peri-tendinous power Doppler (PD) signal. | 21406459 |
| Inflammation, Calcaneal apophysitis | Altered Intercellular Communication | Sever's disease, also known as calcaneal apophysitis, is thought to be an inflammation of the apophysis of the heel, which is open in childhood. | 21406697 |
| Inflammation, Atherosclerosis | Altered Intercellular Communication | Growing evidence supports the role played by inflammation in atherosclerosis. | 21407077 |
| Inflammation, Cerebrovascular accident | Altered Intercellular Communication | There is substantial evidence that inflammation within the central nervous system contributes to stroke risk and recovery. | 21407237 |
| Cerebrovascular accident | Altered Intercellular Communication | Inflammatory conditions increase stroke risk, and the inflammatory response is of major importance in recovery and healing processes after stroke. | 21407237 |
| ARCN1 gene, Inflammation, Chronic Obstructive Airway Disease, Pulmonary Complication | Altered Intercellular Communication | Circulating markers of inflammation in chronic obstructive pulmonary disease (COPD) may correlate to disease progression and extrapulmonary complications such as malnourishment. | 21407820 |
| ARCN1 gene, Inflammation | Altered Intercellular Communication | To characterize differences in circulating markers of inflammation in malnourished female and male patients with COPD. | 21407820 |
| ARCN1 gene, Inflammation, Malnutrition | Altered Intercellular Communication | Our study puts forward evidence of a gender-related difference in systemic inflammation in malnourished patients with COPD in terms of circulating neutrophils being more abundant in female patients. | 21407820 |
| Inflammation, Hematoma, Hypoxia | Altered Intercellular Communication | Human early fracture hematoma is characterized by inflammation and hypoxia. | 21409457 |
| Inflammation, Hematoma, Fracture, Hypoxia | Altered Intercellular Communication | Our data suggest cells in the fracture hematoma (1) adapt to hypoxia and (2) promote inflammation in fracture healing at the mRNA level, indicating early involvement of the immune system. | 21409457 |
| Pain Distress Question, Hemorrhage, Inflammation, Bowel sounds, Concretion of intestine, Flatulence, Obstruction, Malabsorption Syndrome | Altered Intercellular Communication | Clinically they may be asymptomatic or may give rise to symptoms like pain, flatulence and borborygmi, may produce malabsorption syndrome or may present in emergency with different acute pathologies like perforation, haemorrhage, obstruction, enterolith formation and inflammation. | 21409932 |
| Ileus, CTCAE, Inflammation, Pain Distress Question, Perforation (observation), Diverticulum | Altered Intercellular Communication | Eight out of 10 patients presented with perforation of diverticula while 1 patient had severe inflammation of diverticulum causing pain, ileus and acute abdomen. | 21409932 |
| Inflammation, Jejunal diverticula | Altered Intercellular Communication | Inflammation and adhesion are other complications with which jejunal diverticula presented during this study. | 21409932 |
| Autoimmune Diseases, Inflammation, VITILIGO-ASSOCIATED MULTIPLE AUTOIMMUNE DISEASE SUSCEPTIBILITY 1 (finding) | Altered Intercellular Communication | Our study clearly shows that features of inflammation (pruritus)/autoimmunity (halo naevi, thyroid antibodies) are strongly linked to NSV, together with a familial background of vitiligo and autoimmunity. | 21410675 |
| Intradermal Route of Drug Administration | Altered Intercellular Communication | Obese individuals may be at increased risk of iron deficiency (ID), but it is unclear whether this is due to poor dietary iron intakes or to adiposity-related inflammation. | 21411619 |
| Intradermal Route of Drug Administration | Altered Intercellular Communication | This increased risk of ID may be due to the effects of obesity-related inflammation on dietary iron absorption. | 21411619 |
| Inflammation, Heart failure | Altered Intercellular Communication | Inflammation and serum oxidative stress (OS) are important components in heart failure (HF) deterioration. | 21411994 |
| Inflammation, Non-Small Cell Lung Carcinoma, Blood Vessel | Altered Intercellular Communication | We also identified several novel genes whose expression was downregulated in NSCLC, including SGCG, NLRC4, MMRN1, and SFTPD, which are involved in extracellular matrix formation, apoptosis, blood vessel leakage, and inflammation, respectively. | 21412013 |
| Autoimmune Diseases, Inflammation, Granulomatosis with polyangiitis | Altered Intercellular Communication | Wegener's granulomatosis (WG) is a complex autoimmune disease of unknown etiology, frequently involving localized inflammation of the nasal mucosa as an early manifestation. | 21412229 |
| Inflammatory Hepatocellular Adenoma, Cryoglobulinemia, SMN1 wt Allele | Altered Intercellular Communication | The presence of SMA and cryoglobulinemia was not associated with hepatocellular inflammation activity, age, carrier gender or HCV genotype. | 21412592 |
| Communicable Diseases, Inflammation, Parotitis | Altered Intercellular Communication | Chronic parotitis is a troubling clinical condition characterized by repeated infection and inflammation of the parotid gland caused by decreased salivary flow or obstruction. | 21412726 |
| Inflammation | Altered Intercellular Communication | Malacoplakia is an unusual chronic granulomatous inflammation that commonly occurs in the urinary tract. | 21412727 |
| Meningitis | Altered Intercellular Communication | Aseptic meningitis refers to a clinical syndrome of meningeal inflammation in which bacteria cannot be identified in the cerebrospinal fluid (CSF). | 21412795 |
| Dermatitis, Atopic, allergic inflammation, Disease | Altered Intercellular Communication | The capacity of microbial products to inhibit allergic inflammation make them logical candidates for novel therapies in allergic diseases such as atopic dermatitis. | 21413940 |
| Pressure Ulcer, Inflammation, Ischemia | Altered Intercellular Communication | Too strong and constant pressure caused by fixing clips led to skin ischemia, followed by inflammation and decubitus ulcer, and consequently to the penetration of clips into the earlobes. | 21413962 |
| Inflammation, Gastrointestinal mucositis | Altered Intercellular Communication | The most common complications for patients in both study and control group were soft tissue inflammation (mucositis). | 21414134 |
| Inflammation, Endothelial dysfunction, Chronic Kidney Diseases, Atherosclerosis | Altered Intercellular Communication | Endothelial dysfunction, inflammation and atherosclerosis in chronic kidney disease--a cross-sectional study of predialysis, dialysis and kidney-transplantation patients. | 21414625 |
| Inflammation, Endothelial dysfunction, Chronic Kidney Diseases, Atherosclerosis | Altered Intercellular Communication | Systemic inflammation may contribute to endothelial dysfunction and accelerated atherosclerosis in CKD patients. | 21414625 |
| Inflammation, Endothelial dysfunction, Chronic Kidney Diseases, Atherosclerosis | Altered Intercellular Communication | We assessed the relationship among, endothelial dysfunction, early atherosclerosis and inflammation in predialysis, dialysis and post kidney-transplantation CKD patients. | 21414625 |
| Inflammation, Endothelial dysfunction, atherosclerotic | Altered Intercellular Communication | Our findings suggest that endothelial dysfunction and atherosclerotic changes correlate with inflammation. | 21414625 |
| Inflammation, Communicable Diseases, Epithelial metaplasia, Irritation, Squamous metaplasia | Altered Intercellular Communication | The histogenesis of urothelial metaplasia in the seminal vesicle is unclear, but it possibly is a reaction to mechanical irritation, inflammation, or infection, as has been proposed for urothelial metaplasia in the fallopian tube and squamous metaplasia of the pelvic peritoneum. | 21414821 |
| Autistic Disorder, Gastrointestinal inflammation | Altered Intercellular Communication | Only 6% of autistic patients had intestinal inflammation. | 21415091 |
| Lactase deficiency (disorder), Pain Distress Question, Autistic Disorder, Gastrointestinal inflammation | Altered Intercellular Communication | Lactase deficiency not associated with intestinal inflammation or injury is common in autistic children and may contribute to abdominal discomfort, pain and observed aberrant behavior. | 21415091 |
| Diabetes Mellitus | Altered Intercellular Communication | Our results suggest that the metabolic and hormonal changes related to diabetes may play a role in the etiology of GCA independently from BMI. | 21415356 |
| Inflammation, Malignant neoplasm of endometrium, Obesity | Altered Intercellular Communication | It is hypothesized that inflammation may mediate the relationship between obesity and endometrial cancer risk. | 21415362 |
| Inflammation, Tumor necrosis, Malignant neoplasm of endometrium | Altered Intercellular Communication | We examined the associations of three inflammation markers, C-reactive protein (CRP), interleukin (IL)-6 and tumor necrosis factor (TNF)-a, with risk of endometrial cancer. | 21415362 |
| Increased insulin level, Inflammation, Malignant neoplasm of endometrium | Altered Intercellular Communication | The association between inflammation, as indicated by a relatively high level of CRP, and endometrial cancer risk may partially be explained by hyperinsulinemia and elevated estradiol. | 21415362 |
| Inflammation, Malignant neoplasm of endometrium, Obesity | Altered Intercellular Communication | The association between obesity and endometrial cancer risk in postmenopausal women may be attributed to inflammation, insulin resistance, and elevated estrogen. | 21415362 |
| Granulomatous inflammation, Pleurisy, Vasculitis, CTCAE, Geographic Necrosis | Altered Intercellular Communication | Other pathologic findings included granulomatous inflammation with geographic necrosis (3), vasculitis (3), and pleuritis (3). | 21415702 |
| Inflammation, Edema, Pain Distress Question | Altered Intercellular Communication | Endplate signal abnormalities, particularly M1 changes indicating edema and inflammation, have been suggested to play an important role in the etiopathogenesis of a subgroup of patients with nonspecific chronic low back pain (CLBP). | 21415809 |
| Inflammation | Altered Intercellular Communication | The incidences of chronic inflammation in 1 and 2 g/kg males and females were significantly increased. | 21415873 |
| Acute and chronic inflammation | Altered Intercellular Communication | A significantly increased incidence of chronic active inflammation of the nose occurred in 0.5 g/kg males. | 21415873 |
| Acute and chronic inflammation | Altered Intercellular Communication | Also in 0.5 g/kg males, the incidence of chronic active inflammation of the forestomach was increased. | 21415873 |
| Inflammation, Hyperplasia | Altered Intercellular Communication | In the forestomach, there were significantly increased incidences of inflammation and epithelial hyperplasia in 0.5 g/kg females. | 21415873 |
| Inflammation, Takotsubo Cardiomyopathy | Altered Intercellular Communication | Platelet and monocyte activity markers and mediators of inflammation in Takotsubo cardiomyopathy. | 21416113 |
| Inflammation, CD55 gene | Altered Intercellular Communication | We analyzed blood concentrations of mediators of inflammation and platelet- and monocyte-activity markers in patients with TC and MI for significant differences. | 21416113 |
| Amyotrophic Lateral Sclerosis, Inflammation | Altered Intercellular Communication | Cytoskeletal modification and inflammation are known to occur during the pathogenesis of ALS. | 21418221 |
| Inflammation, Metabolic Syndrome X, Hostility | Altered Intercellular Communication | Hostility, metabolic syndrome, inflammation and cardiac control in young adults: The Young Finns Study. | 21419189 |
| Inflammation, Metabolic Syndrome X, Cardiovascular Diseases, Hostility, Choline Dehydrogenase, Mitochondrial | Altered Intercellular Communication | We studied whether there is an association between hostility and cardiovascular heart disease (CHD) risk factors, such as the metabolic syndrome, systemic inflammation and autonomic cardiac control. | 21419189 |
| Inflammation, Metabolic Syndrome X, Hostility | Altered Intercellular Communication | In women, hostility predicted increased risk of metabolic syndrome (EGIR, and the IDF definitions, ORs = 1.34, 1.35, p < 0.05), and higher levels of inflammation (b = 0.09, p < 0.01). | 21419189 |
| Inflammation, Hostility, Metabolic Syndrome X, Choline Dehydrogenase, Mitochondrial | Altered Intercellular Communication | We concluded that hostility is associated with metabolic syndrome and systemic inflammation in women and these conditions may be factors linking hostility to CHD. | 21419189 |
| Polyarteritis Nodosa | Altered Intercellular Communication | Most cases (n = 14) showed polyarteritis nodosa (PAN)-like features with transmural necrotizing inflammation of small-medium arteries. | 21419476 |
| Pyuria, prostatitis | Altered Intercellular Communication | Prostatic inflammation detected in initial biopsy specimens and urinary pyuria are predictors of negative repeat prostate biopsy. | 21420119 |
| prostatitis | Altered Intercellular Communication | Asymptomatic prostatic inflammation may cause increased prostate specific antigen in some men, leading to unnecessary repeat prostate biopsy. | 21420119 |
| Inflammation, Pyuria | Altered Intercellular Communication | Age, prostate specific antigen density, polymorphonuclear leukocyte inflammation in initial biopsy specimens and urinary pyuria are indicators of benign repeat biopsy. | 21420119 |
| Airway structure, Asthma | Altered Intercellular Communication | Prenatal smoke exposure is associated with airway inflammation and asthma in children. | 21422092 |
| Airway structure | Altered Intercellular Communication | Plausibly, airway inflammation from prenatal smoke exposure induces obstructive symptoms more easily in the underdeveloped airways of LBW children. | 21422092 |
| Necrotizing granulomatous inflammation | Altered Intercellular Communication | Punch biopsy specimens demonstrated interstitial dermal granulomatous inflammation. | 21422341 |
| Inflammation, Fibrous, Granulation finding | Altered Intercellular Communication | Four phases of physiological healing were observed: platelet and fibrin deposition, inflammation, granulation tissue, and finally, fibrous encapsulation. | 21422390 |
| Inflammation | Altered Intercellular Communication | In addition to its function in calcium and bone metabolism, vitamin D is neuroprotective and important for mitigating inflammation. | 21422528 |
| Inflammation, Systemic Vasculitis | Altered Intercellular Communication | This is the first reported case of epidural inflammation ascribed to microscopic polyangiitis. | 21422637 |
| Acute Lung Injury, Inflammation | Altered Intercellular Communication | We therefore sought to determine whether enteral fish oil alone would reduce pulmonary and systemic inflammation in patients with acute lung injury. | 21423000 |
| Acute Lung Injury, Inflammation | Altered Intercellular Communication | Fish oil did not reduce biomarkers of pulmonary or systemic inflammation in patients with acute lung injury, and the results do not support the conduct of a larger clinical trial in this population with this agent. | 21423000 |
| Perifolliculitis | Altered Intercellular Communication | Taking the findings of both eyes, the prevalence of trachomatous inflammation-follicular (TF) in children aged 1-9 years was 25.1% (96/383) of whom 13 (13.7%) were PCR positive on the left eye. | 21423648 |
| Inflammation | Altered Intercellular Communication | The cytokine interleukin-10 (IL-10) has a central role in mediating inflammation, which may affect the outcome of the patients with GD. | 21424183 |
| Atrial Fibrillation by ECG Finding | Altered Intercellular Communication | Inflammation-sensitive proteins and risk of atrial fibrillation: a population-based cohort study. | 21424216 |
| Inflammation, Atrial Fibrillation, Atrial Fibrillation by ECG Finding, Cardiovascular Diseases | Altered Intercellular Communication | Low-grade inflammation has been repeatedly associated with cardiovascular diseases but the relationship with incidence of atrial fibrillation (AF) remains unclear. | 21424216 |
| Inflammation, Ischemic stroke | Altered Intercellular Communication | There is increasing evidence that inflammation plays an important role in the progression of acute ischemic stroke (AIS). | 21424610 |
| Carcinogenesis | Altered Intercellular Communication | It is believed that the host genetic factors such as inflammation-induced cytokines may play a role in cervical carcinogenesis. | 21424904 |
| Inflammation, Hemorrhage, fiber, Thickened, Trauma, Nervous System, Chemical injury, Vasculitis | Altered Intercellular Communication | Nerve biopsies were similar to DLPRN showing ischemic injury (multifocal fiber loss [11/23], perineural thickening [18/23], injury neuroma [11/23], neovascularization [17/23]) and evidence of altered immunity and microvasculitis (epineurial perivascular inflammation [23/23], prior bleeding [11/23], vessel wall inflammation [15/23], and microvasculitis [3/23]). | 21425185 |
| Colorectal Carcinoma, Acute and chronic inflammation, Ulcerative Colitis | Altered Intercellular Communication | Patients with extensive, longstanding ulcerative colitis (UC), a disease of chronic colonic inflammation, are at risk for colorectal cancer (CRC). | 21425209 |
| Inflammation | Altered Intercellular Communication | Elucidating the mechanism and fully characterizing the nature of this chronic inflammation offers the potential to identify those at greatest risk. | 21425209 |
| Cyst, Inflammation, Glaucoma, CTCAE | Altered Intercellular Communication | The cyst contents appeared clear and no secondary inflammation or glaucoma occurred. | 21425755 |
| Inflammation, Chronic Obstructive Airway Disease, Erectile dysfunction | Altered Intercellular Communication | The increased prevalence of erectile dysfunction (ED) has been reported in patients with chronic obstructive pulmonary disease, and sustained systemic inflammation seems to play a central role in this linkage. | 21426497 |
| Inflammation, Asthma, Inflammatory disorder | Altered Intercellular Communication | Asthma is also a chronic inflammatory airway disorder, eliciting a low-grade systemic inflammation; however, the influence of asthma on ED has not been investigated. | 21426497 |
| Airway structure, Chronic cough | Altered Intercellular Communication | To explore the relationship between airway inflammation and Toll-like receptor 2 (TLR2) expression on macrophages in induced sputum from chronic cough patients, and to observe the effect of methylprednisolone on this receptor. | 21426732 |
| Inflammation, Malnutrition, Depression, CTCAE, Neutrophil count decreased, Chronic Kidney Diseases | Altered Intercellular Communication | We suspected severe immunosuppression caused by various factors, such as predonisolone administration, chronic renal failure on maintenance hemodialysis, depression, and malnutrition due to chronic inflammation and granulocytopenia as a side effect of ganciclovir. | 21426895 |
| Inflammation, Dyslipidemias, Overweight | Altered Intercellular Communication | In this population, high RBC EPA and DHA were associated with attenuated dyslipidemia and low-grade systemic inflammation among overweight and obese persons. | 21427737 |
| Granulomatous inflammation, Granulomatosis with polyangiitis, Necrosis | Altered Intercellular Communication | Wegener's granulomatosis is a necrotic, granulomatous inflammation of small vessels of the upper and lower airways and kidneys. | 21427813 |
| Communicable Diseases, Inflammation, Peri-Implantitis | Altered Intercellular Communication | In the context of peri-implantitis, TNC might be a marker of bone remodelling rather than inflammation and infection. | 21429069 |
| Acute Lung Injury, Pneumonitis | Altered Intercellular Communication | Hepatocyte growth factor (HGF) is known to be involved in the resolution of pulmonary inflammation and repair of acute lung injury. | 21429184 |
| Inflammation, Nasopharyngeal carcinoma, Nasopharynx, Angiolymphoid hyperplasia, Papilloma | Altered Intercellular Communication | Of all cases, there were 1 of papilloma, 87 of lymphoid follicular hyperplasia and chronic inflammation, 11 of nasopharyngeal cysts, and 25 of nasopharyngeal carcinoma. | 21429337 |
| Narrow Band Imaging, Inflammation, Nasopharynx, Angiolymphoid hyperplasia, Papilloma | Altered Intercellular Communication | Under NBI, the color depths were (+) in papilloma, (++) in nasopharyngeal cysts, and (+++) in lymphoid follicular hyperplasia and chronic inflammation, without abnormal vessels. | 21429337 |
| Cessation of life, Inflammation, Obesity, Cerebrovascular accident | Altered Intercellular Communication | Adiposity, inflammation, and risk for death in black and white men and women in the United States: the Reasons for Geographic and Racial Differences in Stroke (REGARDS) study. | 21430022 |
| Inflammation, Prostate carcinoma | Altered Intercellular Communication | Genetic polymorphisms in inflammation pathway genes and prostate cancer risk. | 21430300 |
| Inflammation, Prostate carcinoma | Altered Intercellular Communication | Chronic inflammation is an important mechanism for the development and progression of prostate cancer (PC). | 21430300 |
| Inflammation | Altered Intercellular Communication | These results suggest that variants in genes within the inflammation pathway may play a role in the development of PC, however, further studies are needed to replicate our findings. | 21430300 |
| Inflammation, Allergic | Altered Intercellular Communication | IL-13 is a major stimulator of inflammation and tissue remodeling at sites of Th2 inflammation, and common single-nucleotide polymorphisms in IL13 are associated with allergic phenotypes in several ethnically diverse populations. | 21430433 |
| allergic inflammation | Altered Intercellular Communication | IL13Q110 has been demonstrated to show that increased allergic inflammation depended on the enhanced IL-13-mediated Th2 effector function. | 21430433 |
| Airway structure | Altered Intercellular Communication | To analyze airway inflammation and remodeling, bronchial lavage fluid (BLF) and endobronchial biopsy specimens were examined. | 21430433 |
| allergic inflammation | Altered Intercellular Communication | Our study demonstrates that Q110/Q110 increases, at least in part, allergic inflammation and the propensity for airway remodeling, thus resulting in low lung function. | 21430433 |
| Inflammation | Altered Intercellular Communication | IL-1b might be inducing RA inflammation through producing pro-inflammatory IL-33 in TNF inhibitor-hypo-responders. | 21431944 |
| Necrotizing granulomatous inflammation, Tuberculosis | Altered Intercellular Communication | Excision biopsy and histopathologic examination revealed necrotizing granulomatous inflammation suggestive of tuberculosis. | 21434554 |
| Hypotension, CTCAE, Ocular Hypotension, Leprosy, Intraocular inflammation | Altered Intercellular Communication | Transient hypotension and hypotony in MB leprosy patients are associated with signs of intraocular inflammation. | 21434594 |
| Rheumatoid Arthritis, Arthritis, Erosion of bone | Altered Intercellular Communication | TWEAK and Fn14 expression in the pathogenesis of joint inflammation and bone erosion in rheumatoid arthritis. | 21435232 |
| Refractory anemias, Inflammation, Rheumatoid Arthritis, Erosion of bone | Altered Intercellular Communication | TNF-like weak inducer of apoptosis (TWEAK) has been proposed as a mediator of inflammation and bone erosion in rheumatoid arthritis (RA). | 21435232 |
| Refractory anemias, Inflammation, Erosion of bone | Altered Intercellular Communication | High levels of sTWEAK in active RA synovial fluid and of TWEAK and Fn14 in active RA tissue, together with the effect of TWEAK to induce osteoblastic RANKL expression, is consistent with TWEAK/Fn14 signalling being important in the pathogenesis of inflammation and bone erosion in RA. | 21435232 |
| Inflammation, Atherosclerosis | Altered Intercellular Communication | Quantification of coronary atherosclerosis and inflammation to predict coronary events and all-cause mortality. | 21435514 |
| Inflammation, SLC25A20 gene, Dental Plaque | Altered Intercellular Communication | Both hsCRP as a measure of inflammation and CAC as a measure of coronary plaque burden have been shown to improve risk appraisal. | 21435514 |
| Coronary Artery Disease, Acute inflammation | Altered Intercellular Communication | Framingham risk variables, hsCRP, and CAC were measured in 3,966 subjects without known coronary artery disease or acute inflammation. | 21435514 |
| Inflammation, SLC25A20 gene, Atherosclerosis | Altered Intercellular Communication | The risk of coronary events and all-cause mortality that is mediated by the presence of coronary atherosclerosis and systemic inflammation can be estimated by CAC and hsCRP. | 21435514 |
| Inflammation, Perforation (observation), Boerhaave syndrome | Altered Intercellular Communication | The results of this study suggest that thoracoscopic esophageal repair may be a good surgical alternative in patients with Boerhaave's syndrome who have a relatively stable vital sign or mild inflammation, regardless of the time interval between perforation and surgery. | 21435633 |
| APP gene, Inflammation, Aortic Aneurysm, Abdominal | Altered Intercellular Communication | Increased angiogenesis, chronic inflammation, and extracellular matrix degradation are the major pathological features of abdominal aortic aneurysm (AAA). | 21436157 |
| Inflammation, Pneumonia | Altered Intercellular Communication | Increased lung neutrophil apoptosis and inflammation resolution in nonresponding pneumonia. | 21436352 |
| Inflammation | Altered Intercellular Communication | After 72 h of treatment, an increased basal alveolar neutrophil apoptosis might contribute to downregulation of inflammation and to faster clinical stability. | 21436352 |
| Pain Distress Question, Bone Marrow Diseases, Proliferative inflammation | Altered Intercellular Communication | HSP is a rare disease characterized by hypertrophic inflammation of the dura mater and clinical symptoms that progress from local pain to myelopathy. | 21436740 |
| Bone Diseases, Inflammation | Altered Intercellular Communication | Association of ankle-arm index with inflammation and mineral bone disorder in hemodialysis patients. | 21437516 |
| Inflammation, Metabolic Bone Disorder, HD Term Type, Bone Diseases, Cardiac complication, Cessation of life | Altered Intercellular Communication | Reduced ankle-arm index (AAI), inflammation and mineral bone disorder (MBD) are all associated with increased risk of death and cardiovascular complications in patients on hemodialysis (HD), but the association between them deserves clarification. | 21437516 |
| HD Term Type, Inflammation | Altered Intercellular Communication | To evaluate the association between abnormal AAI with MBD and inflammation in patients on HD. | 21437516 |
| Inflammation | Altered Intercellular Communication | The risk of having low AAI seems to be increased by aging and inflammation, whereas BMD was associated with high AAI. | 21437516 |
| Inflammation, Normocytic anemia, microcytic | Altered Intercellular Communication | To examine the impact of a body fat content on the concentration of a serum prohepcidin, iron metabolism parameters and inflammation markers in elderly patients with microcytic or normocytic anemia. | 21437556 |
| Airway structure, Asthma, Asthma attack | Altered Intercellular Communication | Treating children asthma by integrated traditional Chinese and western medicine can obviously reduce IL4 and IL-13, increase IFN-gamma, and therefore lighten the airway inflammation, prevent asthma attacks effectively. | 21438413 |
| Inflammation, Metabolic Syndrome X | Altered Intercellular Communication | Metabolic syndrome is associated with higher C-reactive protein (CRP) serum levels, a common biological marker of inflammation. | 21438714 |
| Inflammation, Metabolic Syndrome X | Altered Intercellular Communication | However, the respective contribution of each component of metabolic syndrome to the inflammation has not been established. | 21438714 |
| Hereditary Autoinflammatory Diseases, Inflammation, Fever, CTCAE, Brucellosis, Familial Mediterranean Fever | Altered Intercellular Communication | Familial Mediterranean fever (FMF) is an autoinflammatory disease characterized by recurrent episodes of fever and serosal or synovial inflammation. | 21438869 |
| Gastrointestinal inflammation | Altered Intercellular Communication | Chemokine CXCL11 links microbial stimuli to intestinal inflammation. | 21438871 |
| Gastrointestinal inflammation | Altered Intercellular Communication | In a skewed Th1 response environment flagellin induces intestinal inflammation, with IL-17 expression predominant. | 21438871 |
| Gastrointestinal inflammation | Altered Intercellular Communication | CXCR3/CXCL11 pathway is involved in microbial product flagellin-induced intestinal inflammation in which the Th17 response plays an important role. | 21438871 |
| Waldenstrom Macroglobulinemia, Atrophic | Altered Intercellular Communication | Microscopically, all CSS-cases showed similar morphology with preservation of lobular architecture accentuated by cellular fibrous bands, dense lymphoplasmacytic inflammation and varied acinar atrophy. | 21438912 |
| Pain Distress Question, Inflammation | Altered Intercellular Communication | Canakinumab 150 mg provided significantly greater and more rapid reduction in pain and signs and symptoms of inflammation compared with triamcinolone acetonide 40 mg. | 21439048 |
| Airway structure, Asthma | Altered Intercellular Communication | Fractionated exhaled nitric oxide (FeNO) expression is increased in airway inflammation and several studies have suggested that FeNO measurement can be useful in patients with asthma. | 21439165 |
| Inflammation, Malnutrition | Altered Intercellular Communication | In this respect, the association between malnutrition and inflammation may be a confounding factor in the determination of the true relationship between Hcy, nutritional status, and cardiovascular risk factors in this group. | 21439851 |
| Inflammation | Altered Intercellular Communication | Hemodialysis induces p66(shc) gene expression in nondiabetic humans: correlations with oxidative stress and systemic inflammation. | 21439852 |
| Inflammation, Malnutrition, Cardiovascular Diseases | Altered Intercellular Communication | Oxidative stress and inflammation characterize hemodialysis (HD) and are associated with malnutrition, cardiovascular disease, and poor clinical outcome. | 21439852 |
| HD Term Type, Inflammation | Altered Intercellular Communication | p66(shc) messenger ribonucleic acid (mRNA) was compared with systemic oxidative stress and inflammation markers in control subjects and patients on HD before and after a single HD session in a cross-sectional analysis. | 21439852 |
| Perineural spread, Inflammation | Altered Intercellular Communication | The incidence of angiolymphatic invasion, visceral pleural invasion, and degree of tumor inflammation, as well as morbidity, mortality, and length of stay were similar between segmentectomy and lobectomy. | 21440123 |
| Inflammation | Altered Intercellular Communication | There was a trend for decreased recurrence with increasing tumor inflammation (mild versus severe, p = 0.066). | 21440123 |
| Inflammation, Neoplasms | Altered Intercellular Communication | The clinical course of the patient suggests that the tumor produced interleukin-6 and this was associated not only with inflammation, but also the aggressive biologic behavior of the tumor. | 21440168 |
| Chronic sinusitis, Craniosynostosis, Inflammatory disease of mucous membrane | Altered Intercellular Communication | It is unclear whether mucosal inflammation has an effect on the bone under the mucosa in patients with chronic rhinosinusitis (CRS). | 21442077 |
| Inflammation, Malnutrition | Altered Intercellular Communication | Inflammation can lead to malnutrition to some extent. | 21442152 |
| Refractory anemias, Inflammation, Rheumatoid Arthritis, Atherosclerosis | Altered Intercellular Communication | Systemic inflammation may be a common process that underpins both atherosclerosis and extra-articular features (ExRA) of rheumatoid arthritis (RA). | 21442165 |
| Inflammation, Bacterial resistance | Altered Intercellular Communication | Based on other work regarding intestinal bacteria, we hypothesize a relationship between chronic inflammation of the appendix from bacterial overgrowth and Ki-ras gene mutation. | 21443421 |
| Inflammation, Primary malignant neoplasm, Cardiovascular Diseases | Altered Intercellular Communication | Food patterns, inflammation markers and incidence of cardiovascular disease: the Malmo Diet and Cancer study. | 21443679 |
| Heart Diseases, Inflammation | Altered Intercellular Communication | Systemic inflammation (SI) is associated with impairment of cardiac autonomic modulation (CAM), which is associated with cardiac disease. | 21444250 |
| Inflammation, Choline Dehydrogenase, Mitochondrial | Altered Intercellular Communication | There was no association with a panel of CHD biomarkers, including any lipid, inflammation, or coagulation trait, nor with telomere length. | 21444365 |
| Inflammation, Bacterial Infections | Altered Intercellular Communication | Thus, we propose that secretion of AGEs by bacteria is a novel avenue of bacterial-induced inflammation which is potentially important in the pathophysiology of bacterial infections. | 21445354 |
| Inflammation | Altered Intercellular Communication | These findings provide evidence that neurons in MS are respiratory-deficient due to mtDNA deletions, which are extensive in GM and may be induced by inflammation. | 21446022 |
| Narcolepsy | Altered Intercellular Communication | Similarly to that reported in patients with narcolepsy, the cortical hypoexcitability may reflect the deficiency of the excitatory hypocretin/orexin-neurotransmitter system. | 21446790 |
| Primary Myelofibrosis, Inflammation | Altered Intercellular Communication | The interferon signature may reflect primary myelofibrosis as the burn-out phase of chronic inflammation which ultimately elicits clonal evolution and expansion owing to an exaggerated but incompetent antitumor immune response. | 21447007 |
| Airway structure, ARCN1 gene, Chronic Obstructive Airway Disease | Altered Intercellular Communication | Airway inflammation in chronic obstructive pulmonary disease (COPD) is believed to be insensitive to corticosteroids. | 21447053 |
| Inflammation, Atrial Fibrillation by ECG Finding | Altered Intercellular Communication | Histological studies support the important role of inflammation in the initiation and maintenance of atrial fibrillation (AF). | 21447517 |
| Panniculitis | Altered Intercellular Communication | We describe a novel and safe technique of atrial biopsy during AF radiofrequency catheter ablation (RFCA) to investigate the role of atrial tissue inflammation. | 21447517 |
| Inflammation, Rheumatoid Arthritis | Altered Intercellular Communication | Variants of gene for microsomal prostaglandin E2 synthase show association with disease and severe inflammation in rheumatoid arthritis. | 21448233 |
| Refractory anemias, Inflammation | Altered Intercellular Communication | Our data reveal a possible influence of PTGES polymorphism on the pathogenesis of RA and on disease severity through upregulation of mPGES-1 at the sites of inflammation. | 21448233 |
| Chronicity, Inflammation, Depression, CTCAE | Altered Intercellular Communication | Leukocyte telomere length in major depression: correlations with chronicity, inflammation and oxidative stress--preliminary findings. | 21448457 |
| Inflammation | Altered Intercellular Communication | When telomeres critically shorten, as often occurs with repeated mitoses or in response to oxidation and inflammation, cells may die. | 21448457 |
| Minimal Disseminated Disease, Depressive disorder, Inflammation, Depression, CTCAE | Altered Intercellular Communication | We sought to determine if leukocyte telomeres are shortened in Major Depressive Disorder (MDD), whether this is a function of lifetime depression exposure and whether this is related to putative mediators, oxidation and inflammation. | 21448457 |
| Inflammation, Depressed mood | Altered Intercellular Communication | Telomere length was inversely correlated with oxidative stress in the depressed subjects (p<0.01) and in the controls (p<0.05) and with inflammation in the depressed subjects (p<0.05). | 21448457 |
| Minimal Disseminated Disease, Inflammation | Altered Intercellular Communication | This might be related to cumulative exposure to oxidative stress and inflammation in MDD. | 21448457 |
| Kidney Failure, Chronic, Inflammation, Metabolic Diseases, Protein-Energy Malnutrition | Altered Intercellular Communication | Protein-energy malnutrition, systemic inflammation, and metabolic disorders are frequent among patients with chronic kidney failure undergoing dialysis, contributing to their morbidity and mortality. | 21448521 |
| Inflammation, Dental Plaque | Altered Intercellular Communication | Also PCR has an important role such as marker of plaque stability and of inflammation. | 21448539 |
| Dyspnea, Airway structure | Altered Intercellular Communication | The highest-rated problems were dyspnoea, activity limitation and airway inflammation, and these areas had good patient-physician concordance. | 21448550 |
| ARCN1 gene, Asthma, Dyspnea, Airway structure | Altered Intercellular Communication | In asthma and COPD, patients and their physicians agree about the importance of managing activity limitation, dyspnoea, and airway inflammation. | 21448550 |
| Steatohepatitis, Weight decreased, Inflammation | Altered Intercellular Communication | BIA deserves more investigations concerning liver steatosis and ongoing inflammation, and it could contribute as well, synergistically with anthropometry, to monitor weight loss, body fat shifts, and metabolic risk. | 21448907 |
| vascular inflammations | Altered Intercellular Communication | Plasma levels of eight mediators of vascular inflammation and endothelial activation, sampled from different vascular compartments. | 21450032 |
| glycation, Inflammation | Altered Intercellular Communication | The receptor for advanced glycation end products (RAGE) is a multiligand signal transduction receptor that can initiate and perpetuate inflammation. | 21450080 |
| Inflammation, Chronic heart failure, Endothelial dysfunction, Congestive heart failure | Altered Intercellular Communication | A reciprocal link between inflammation, oxidative/nitrosative stress, and endothelial dysfunction has been postulated in chronic heart failure (CHF). | 21450636 |
| Sjogrens Syndrome", PEELING SKIN SYNDROME | Altered Intercellular Communication | Primary Sjogren's syndrome (pSS) is characterised by a chronic inflammation of exocrine glands. | 21450750 |
| Arteritis | Altered Intercellular Communication | In particular, IL-32 seems to be an important mediator of artery inflammation in GCA. | 21452292 |
| Inflammation, Ichthyosis Bullosa of Siemens, Irritable Bowel Syndrome, Cell Stress Process | Altered Intercellular Communication | Irritable bowel syndrome (IBS) is a stress-related disorder with disturbed brain-gut communication, gastrointestinal homeostasis and, based on recent evidence, low grade inflammation and an altered microbiota. | 21453321 |
| Inflammation | Altered Intercellular Communication | The budesonide-soaked Merocel MMS showed a trend toward reduced mucosal inflammation when compared to the control Merocel MMS, but the results were not statistically significant. | 21453656 |
| Inflammation, Chronic Obstructive Airway Disease | Altered Intercellular Communication | Molecular mechanisms of inflammation during exacerbations of chronic obstructive pulmonary disease. | 21454005 |
| Inflammation | Altered Intercellular Communication | Moreover, C pneumoniae-specific IgG was significantly correlated with hsCRP among ACAD patients, suggesting an important role of these organisms in the development of CAD by altering lipid profile and induction of inflammation. | 21454155 |
| Inflammation | Altered Intercellular Communication | C-C motif ligand 3 (CCL3) chemokine plays a crucial role in the inflammation process, cell migration and chemoattraction of monocytes/macrophages, neutrophils and mast cells. | 21454208 |
| ARCN1 gene, Airway structure | Altered Intercellular Communication | Seventy-five patients with COPD (58 men, 17 women) were studied with CT imaging and with measures of airway inflammation. | 21454400 |
| Airway structure | Altered Intercellular Communication | There was no difference in airway inflammation, exacerbation frequency, or bacterial load in patients with EM alone or with BE and/or BWT +- EM. | 21454400 |
| ARCN1 gene, Inflammation | Altered Intercellular Communication | Adenosine and related purines have established roles in inflammation, and elevated airway concentrations are predicted in patients with COPD. | 21454402 |
| Inflammation, Tooth Loss, Impaired cognition | Altered Intercellular Communication | Several mechanisms may associate tooth loss and related oral inflammation with cognitive impairment. | 21454843 |
| Inflammation | Altered Intercellular Communication | In the PRT group, mid-tibia muscle cross-sectional area increased less in men with higher pre-training inflammation compared with those men with lower inflammation (net difference ~2.5%, p < 0.05). | 21455612 |
| Inflammation, Muscle hypertrophy | Altered Intercellular Communication | Furthermore, low-grade inflammation at baseline restricted muscle hypertrophy following PRT. | 21455612 |
| Inflammation, Ulcerative Colitis | Altered Intercellular Communication | The fact that no correlation was found between mucosal hydrophobicity and disease activity may indicate that the loss of mucosal hydrophobicity in UC is not exclusively a secondary effect due to inflammation. | 21455745 |
| Inflammation, Anemia | Altered Intercellular Communication | Moreover, we found that decrease in the renal function, duration of mHD, and inflammation may contribute to these above-mentioned changes, which are probably the factors that should be taken into account when explaining the mechanisms of persistence of anaemia in haemodialysed patients. | 21455763 |
| Inflammation | Altered Intercellular Communication | Histopathological signs of inflammation involved the right colon in 86% of patients and were purely right-sided in 23%. | 21456044 |
| Inflammation | Altered Intercellular Communication | The findings of inflammation were higher in the right compared to the left colon (P < 0.001), but the general inflammatory activity was low. | 21456044 |
| Inflammation, Malignant Neoplasms, Colitis | Altered Intercellular Communication | PSC-IBD may represent a distinct entity of colitis in which low endoscopic activity may mask an active histologic inflammation that possibly contributes to an increased risk of malignancy. | 21456044 |
| Colitis | Altered Intercellular Communication | Circumstances related to liver transplantation seem to act favorably on colonic inflammation in PSC. | 21456044 |
| Inflammation, Impaired T cell function | Altered Intercellular Communication | Also, patients suffer from b-cell dysfunction, chronic systemic inflammation, increased hormonal visceral adipose tissue activity, and an increased risk of cardiovascular events. | 21457065 |
| Inflammation, Impaired T cell function | Altered Intercellular Communication | Also, patients suffer from b-cell dysfunction, chronic systemic inflammation, increased hormonal visceral adipose tissue activity, and an increased risk of cardiovascular events. | 21457065 |
| Inflammation, Chronic Kidney Diseases | Altered Intercellular Communication | Reduced glomerular filtration rate, inflammation and HDL cholesterol as main determinants of superoxide production in non-dialysis chronic kidney disease patients. | 21457070 |
| Inflammation, Fibrosis Assessment, Non-alcoholic Fatty Liver Disease | Altered Intercellular Communication | Serum ferritin is a discriminant marker for both fibrosis and inflammation in histologically proven non-alcoholic fatty liver disease patients. | 21457446 |
| Inflammation, Fibrosis Assessment, Non-alcoholic Fatty Liver Disease, Metabolic Syndrome X | Altered Intercellular Communication | We evaluated serum ferritin and the features of metabolic syndrome with respect to histological inflammation and/or fibrosis in NAFLD patients. | 21457446 |
| Inflammation, Fibrosis Assessment, Diabetes Mellitus, Fatty Liver Disease | Altered Intercellular Communication | Multivariate regression showed that diabetes, serum ferritin concentrations, body mass index (BMI) and AST were independently associated with NASH: together, the areas under the receiver operating characteristic (AUROC) was 0.91 (95% confidence interval 0.86-0.96); fibrosis was associated with ferritin concentrations and BMI: AUROC 0.87, portal inflammation with ferritin and DM: AUROC 0.82, while lobular inflammation was associated with BMI, DM and ferritin: AUROC 0.85. | 21457446 |
| Inflammation, Fibrosis Assessment, Non-alcoholic Fatty Liver Disease | Altered Intercellular Communication | Serum ferritin concentrations and BMI are strongly associated with fibrosis, portal and lobular inflammation in NAFLD patients. | 21457446 |
| Inflammation, Fibrosis Assessment | Altered Intercellular Communication | Both ferritin and BMI are potential discriminant markers to select patients for liver biopsy and are associated with inflammation and fibrosis. | 21457446 |
| Acute Coronary Syndrome, vascular inflammations, GDC AJCC Clinical Stage Terminology | Altered Intercellular Communication | To identify systemically detectable vascular inflammation associated to redox system unbalance, advanced oxidation protein products (AOPP), formed by HClO reaction with proteins, Thiol levels, and their ratio (AOPP/Thiol ratio) were measured in patients with acute coronary syndromes (ACS). | 21458436 |
| Airway structure, Fibromuscular Dysplasia | Altered Intercellular Communication | The aim of the present study is to determine whether increased levels of PGE(2) from NAEB sputum supernatants play a protective role in airway inflammation and muscular hyperplasia. | 21458581 |
| Airway structure, Communicable Diseases, Lung Injury | Altered Intercellular Communication | These help establish a 'vicious cycle' of impaired mucociliary clearance, infection, airway inflammation and progressive lung injury. | 21458739 |
| Inflammation | Altered Intercellular Communication | Increased UACR was not associated with markers of inflammation or of renin angiotensin aldosterone system activation and was not reduced by aliskiren. | 21459891 |
| Inflammation, Fibrosis Assessment, Aortic Stiffness | Altered Intercellular Communication | Hepatic stiffness, relative fat fraction, inflammation grade, and fibrosis stage were assessed from MR elastography, in-phase and out-of-phase gradient-echo imaging, and liver biopsy histopathologic review, respectively. | 21460032 |
| Inflammation, Fibrosis Assessment, Fatty degeneration, Aortic Stiffness | Altered Intercellular Communication | The mean hepatic stiffness for patients with simple steatosis (2.51 kPa) was less (P = .028) than that for patients with inflammation but no fibrosis (3.24 kPa). | 21460032 |
| Fibrosis, Liver, Inflammation, Fibrosis Assessment, Aortic Stiffness | Altered Intercellular Communication | The mean hepatic stiffness for patients with inflammation but no fibrosis was less (P = .030) than that for patients with hepatic fibrosis (4.16 kPa). | 21460032 |
| Inflammation, Steatohepatitis, Fibrosis Assessment, Fatty degeneration, Non-alcoholic Fatty Liver Disease, Aortic Stiffness, Liver Stiffness | Altered Intercellular Communication | In patients with NAFLD, hepatic stiffness measurements with MR elastography can help identify individuals with steatohepatitis, even before the onset of fibrosis; NAFLD patients with inflammation but no fibrosis have greater liver stiffness than those with simple steatosis and lower mean stiffness than those with fibrosis. | 21460032 |
| Inflammation, Edema | Altered Intercellular Communication | On initial examination, he presented with a stromal edema involving the inferior half of the cornea, epithelial microcysts, and moderate chamber inflammation. | 21461226 |
| Inflammation, Corneal edema | Altered Intercellular Communication | One month after the initial visit, anterior chamber inflammation was improved and his visual acuity recovered to 20/20, but subtle corneal edema still remained. | 21461226 |
| Hypospadias, Diabetes Mellitus, Cryptorchidism, Obesity | Altered Intercellular Communication | Maternal obesity, which increases risk of diabetes and could influence hormone levels, may, therefore, be associated with risk of hypospadias and cryptorchidism. | 21462299 |
| Inflammation, Infection | Altered Intercellular Communication | Malakoplakia is an inflammation which is thought to develop secondary to chronic Escherichia coli infections. | 21463841 |
| Inflammation | Altered Intercellular Communication | Our previous studies have shown that exposure to inflammatory stimuli resulted in elevated LCN2 levels in brain microglia and astrocytes implicating LCN2 in brain inflammation. | 21463871 |
| Inflammation, millicurie, Data types - Address | Altered Intercellular Communication | MCI represents a prodromal stage of AD, and inflammation occurs as one of the earliest pathological events in AD. | 21463871 |
| Peripheral Vascular Diseases, Inflammation | Altered Intercellular Communication | Markers of inflammation in relation to long-term cardiovascular mortality in patients with lower-extremity peripheral arterial disease. | 21463908 |
| Rupture, vascular inflammations, Dental Plaque, Atherosclerosis | Altered Intercellular Communication | Elevated levels of inflammatory mediators reflect vascular inflammation, and play a significant role in the genesis of atherosclerosis, plaque instability and rupture. | 21463908 |
| Stargardts disease", Inflammation | Altered Intercellular Communication | Complement system dysregulation and inflammation in the retinal pigment epithelium of a mouse model for Stargardt macular degeneration. | 21464132 |
| Inflammation | Altered Intercellular Communication | Age-related macular degeneration, a prevalent blinding disease of the elderly, is strongly associated with mutations in the genes for complement regulatory proteins (CRP), causing chronic inflammation of the RPE. | 21464132 |
| Inflammation, ABCA4 gene | Altered Intercellular Communication | Thus, Stargardt disease and age-related macular degeneration may both be caused by chronic inflammation of the RPE. | 21464132 |
| Atherogenesis, Inflammation, Acute myocardial infarction, Congenital Abnormality | Altered Intercellular Communication | On the basis of the role of activin A in inflammation, atherogenesis, and glucose homeostasis, we investigated whether activin A could be related to glucometabolic abnormalities in patients with acute myocardial infarction (MI). | 21464440 |
| Inflammation, Hyperglycemia | Altered Intercellular Communication | Our in vitro findings suggest that this association represents a counteracting mechanism to protect against inflammation, hyperglycemia, and oxidative stress. | 21464440 |
| Inflammation, Atherosclerosis | Altered Intercellular Communication | L-selectin is a member of the selectin family of cell adhesion molecules which are important in the transient attachment of leukocytes to endothelial cells, which plays a role in inflammation processes and is one of the earliest events in the pathogenesis of atherosclerosis. | 21465128 |
| Inflammation, Irritation - emotion, Dental caries | Altered Intercellular Communication | These findings are a confirmation that denticles appear during chronic inflammation as the consequence of pulp irritation caused by caries or fillings. | 21465852 |
| Adenocarcinoma | Altered Intercellular Communication | The most frequent diagnosis was adenocarcinoma mostly of pancreas followed by chronic granulomatous inflammation of mediastinal and abdominal lymph nodes. | 21465975 |
| Inflammation | Altered Intercellular Communication | Data indicate that levels of FAs and their composition may influence myocardial function and inflammation. | 21466599 |
| Inflammation | Altered Intercellular Communication | (iii) These changes in FA composition were significantly associated with functional class, impaired cardiac function (i.e., decreased cardiac index and increased plasma N-terminal pro-B-type natriuretic peptide levels) and enhanced systemic inflammation (i.e., increased high-sensitivity C-reactive protein levels). | 21466599 |
| Sepsis, Inflammation, Adrenal cortical hypofunction | Altered Intercellular Communication | This finding might have impact on interpreting previous and designing future trials on diagnosing and modulating immunoendocrine dysregulation (for example, adrenal insufficiency) during systemic inflammation and sepsis. | 21466684 |
| Inflammation, Cell Death | Altered Intercellular Communication | Activation of factor VII-activating protease in human inflammation: a sensor for cell death. | 21466697 |
| Sepsis, Inflammation | Altered Intercellular Communication | Circulating nucleosomes were suggested to play an important role in inflammation and were demonstrated to correlate with severity and outcome in sepsis patients. | 21466697 |
| Cessation of life, Inflammation, palladium, Parkinson Disease | Altered Intercellular Communication | Among the pathogenic processes contributing to dopaminergic neuron (DN) death in Parkinson disease (PD), evidence points to non-cell-autonomous mechanisms, particularly chronic inflammation mounted by activated microglia. | 21467220 |
| palladium | Altered Intercellular Communication | Together, our data indicate that GR is important in curtailing microglial reactivity, and its deregulation in PD could lead to sustained inflammation-mediated DN injury. | 21467220 |
| Pancreatic carcinoma | Altered Intercellular Communication | Inflammation-related gene variants as risk factors for pancreatic cancer. | 21467233 |
| Inflammation, Pancreatic carcinoma | Altered Intercellular Communication | Recent reports support an association between chronic inflammation and progression to pancreatic cancer (PC). | 21467233 |
| Inflammation, ovarian neoplasm | Altered Intercellular Communication | Circulating inflammation markers and risk of epithelial ovarian cancer. | 21467242 |
| Inflammation, ovarian neoplasm | Altered Intercellular Communication | Factors contributing to chronic inflammation appear to be associated with increased risk of ovarian cancer. | 21467242 |
| Takotsubo Cardiomyopathy, Hyponatremia | Altered Intercellular Communication | Takotsubo cardiomyopathy in a patient with severe hyponatremia associated with syndrome of inappropriate antidiuretic hormone. | 21467706 |
| diabetic | Altered Intercellular Communication | Results indicated that the fibrin network in all diabetic patients had thickened masses of thin, minor fibres over the major fibres, a profile typical of an inflammatory condition. | 21467917 |
| Unknown (origin) (qualifier value), Inflammation | Altered Intercellular Communication | Xanthogranulomatous inflammation (XGI) is a rare, idiopathic process in which lipid-laden histiocytes are deposited at various locations in the body. | 21468270 |
| CLU protein, human, Inflammation | Altered Intercellular Communication | Our results show that CLI is strongly correlated to inflammation, indicating a strong potential for proteomics analysis in the diagnosis of CLI. | 21468429 |
| Germinoma, Inflammation | Altered Intercellular Communication | The granulomatous inflammation occurring around germinomas can cause histological diagnostic difficulty. | 21469434 |
| Inflammation, Pain Distress Question | Altered Intercellular Communication | Dietary interventions involving antioxidants are of interest for reducing inflammation, improving joint motion, and altering pain perception. | 21470042 |
| Inflammation, Prostate carcinoma, Structure of posterior cerebral artery | Altered Intercellular Communication | The origin of chronic inflammation preceding the development of prostate cancer (PCa) remains unknown. | 21471611 |
| glycation, Inflammation, Overactive | Altered Intercellular Communication | The distribution and expression of cannabinoid receptors 1 (CNR1) and 2 (CNR2) in combination with inflammatory cytokines and RAGE (receptor of advanced glycation end products), which is also overactive in these diseases, in dependency of the extent of inflammation and alteration of the colon barrier is still unclear and needs to be elucidated. | 21472688 |
| Inflammatory Bowel Diseases, Inflammation | Altered Intercellular Communication | We showed that cannabinoid receptors are expressed differentially in inflammatory bowel disease and that the expression seems to be influenced by the underlying disease and by localized inflammation. | 21472688 |
| Inflammation, Pulmonary function tests | Altered Intercellular Communication | The patient expressed marked eosinophilic inflammation and marked deterioration of pulmonary function while in persistent contact with the causal agent. | 21472745 |
| Intraocular inflammation, Hypertrophy | Altered Intercellular Communication | USG, CT and NMR scans revealed the intraocular inflammation and inflammatory enlargement of both lacrimal glands. | 21473083 |
| Intraocular inflammation, Lacrimal gland structure | Altered Intercellular Communication | Within weeks the intraocular inflammation was under control and the resolution of lacrimal glands edema was noted. | 21473083 |
| Intraocular inflammation, Chronic Lymphocytic Leukemia | Altered Intercellular Communication | Chronic lymphocytic leukemia rarely masks as chronic intraocular inflammation, in a sporadic cases however it may herald the relapse of the disease. | 21473083 |
| Pharyngitis | Altered Intercellular Communication | Immunohistochemical and western blot method were used to determine the expression of human nuclear distribution C in 80 cases of NPC and 30 cases of chronic inflammation of nasopharyngeal mucosa. | 21473139 |
| Pharyngitis | Altered Intercellular Communication | The positive expression rate of human nuclear distribution C in NPC was 83.75%, which was higher than that in chronic inflammation of nasopharyngeal mucosa 23.33% (P < 0.05). | 21473139 |
| Inflammation, Refractory anemias, Degenerative polyarthritis, Rheumatoid Arthritis, Arthritis | Altered Intercellular Communication | To evaluate the applicability of a lentiviral (LV) serum amyloid A3 (Saa3)-promoter luciferase (Luc) reporter for assessing inflammation in experimental arthritis, synovial fibroblasts (SF) from osteoarthritis (OA) and rheumatoid arthritis (RA) patients. | 21474483 |
| Arthritis, Streptococcus, Exacerbation of cGVHD | Altered Intercellular Communication | In mice, synovium was transduced in vivo by cholesterol optimised LV, and two flares of acute joint inflammation were induced by injection of streptococcal cell wall (SCW) material into the knee-joint cavity. | 21474483 |
| Inflammation | Altered Intercellular Communication | The time course of synovial inflammation was assessed using ex vivo luciferase assays, and histology. | 21474483 |
| Inflammation, Synovitis | Altered Intercellular Communication | The Saa3-promoter activities during acute inflammation correlated with Tc uptake measurements but were more sensitive and able to respond to the ongoing synovitis in the chronic phase of SCW arthritis. | 21474483 |
| Hyperglycemia, Inflammation, Brain Injuries, Cerebral Hemorrhage | Altered Intercellular Communication | Hyperglycemia and inflammation are involved in the progression of spontaneous intracerebral hemorrhage (sICH)-induced brain injury, but their role in predicting clinical outcome is not clear. | 21474813 |
| Inflammation, Atherosclerosis | Altered Intercellular Communication | Role of interleukin 17 in inflammation, atherosclerosis, and vascular function in apolipoprotein e-deficient mice. | 21474820 |
| Inflammation, Dental Plaque, Atherosclerosis | Altered Intercellular Communication | IL17 contributes to vascular and systemic inflammation in experimental atherosclerosis but does not alter plaque burden. | 21474820 |
| Inflammation | Altered Intercellular Communication | Low signals around the stent struts and tubular structure in the deep layer were also detected, suggesting the existence of inflammation and neovascularization, respectively. | 21474860 |
| Inflammation, Primary malignant neoplasm | Altered Intercellular Communication | This reflects the importance of inflammation in cancer survival. | 21476028 |
| Coronary Aneurysm, Inflammation | Altered Intercellular Communication | Electrocardiogram and physical examination were normal without any clinical signs of inflammation, but computed tomography (CT) scan and cardiac magnetic resonance imaging (MRI) revealed a giant (>50mm) coronary aneurysm. | 21478051 |
| Inflammation, Nasal Polyps, Chronic sinusitis | Altered Intercellular Communication | The nasal polyp (NP) seems to represent the end-stage of longstanding inflammation in patients with chronic rhinosinusitis. | 21478105 |
| Airway structure | Altered Intercellular Communication | Asthma is characterised by chronic airway inflammation and remodelling, which can be (partially) suppressed by inhaled corticosteroids (ICSs). | 21478212 |
| Inflammation, Dermatitis | Altered Intercellular Communication | Here, we present 2 patients treated with imiquimod, whose biopsies showed interface dermatitis of the epidermis and the adnexae with prominent periadnexal and perivascular lymphocytic inflammation. | 21478730 |
| Colorectal Carcinoma | Altered Intercellular Communication | Our data suggest the importance of CYP19A1 in the development of colon and rectal cancer and that estrogen may influence risk through an inflammation-related mechanism. | 21479914 |
| Ischemia, Inflammation, Corneal edema | Altered Intercellular Communication | 1 / 5 showed an anterior ischaemia with corneal oedema, anterior chamber inflammation and pupillotonia, but without involvement of the fundus. | 21480161 |
| Inflammation, Neoplasms | Altered Intercellular Communication | Although pretherapeutic radiological examination is a very useful technique for the evaluation of tumor invasion into specific laryngeal subsites, the pretherapeutic radiologic staging can be challenging when distinguishing tumor from peritumoral inflammation. | 21480760 |
| Inflammation, Acute Coronary Syndrome, Atherosclerosis, GDC AJCC Clinical Stage Terminology | Altered Intercellular Communication | Inflammation plays an important role in the pathogenesis of atherosclerosis and acute coronary syndromes (ACS). | 21481602 |
| Inflammation, Pancreatitis, Pancreatic Ductal Adenocarcinoma | Altered Intercellular Communication | Chronic pancreatitis is a well-known risk factor for pancreatic ductal adenocarcinoma (PDA) development in humans, and inflammation promotes PDA initiation and progression in mouse models of the disease. | 21481787 |
| Orbital Pseudotumor | Altered Intercellular Communication | Orbital inflammation with IgG4-positive plasma cells: manifestation of IgG4 systemic disease. | 21482868 |
| Inflammation, Giant Cell Arteritis | Altered Intercellular Communication | An ipsilateral temporal artery biopsy revealed inflammation that was mistakenly identified as giant cell arteritis. | 21482932 |
| Inflammation | Altered Intercellular Communication | Skeletal muscle aging is associated with increased inflammation and oxidative stress, a decrease in the ability to rebuild muscle after injury and in response to exercise. | 21483036 |
| Infiltration, Breast Carcinoma | Altered Intercellular Communication | The associations between CLEVER-1 expression on endothelial vessels and macrophage/leukocyte infiltration is suggestive of its regulation by inflammatory conditions in breast cancer, most likely by macrophage-associated cytokines. | 21483103 |
| Inflammation, atherosclerotic | Altered Intercellular Communication | Inflammation and biomechanical factors have been associated with the development of vulnerable atherosclerotic plaques. | 21483158 |
| Inflammation, Dental Plaque | Altered Intercellular Communication | All patients had plaque inflammation as shown by intraplaque accumulation of ultrasmall super paramagnetic particles of iron oxide on magnetic resonance imaging at baseline. | 21483158 |
| Inflammation, Cerebrovascular Circulation, Coronary heart disease | Altered Intercellular Communication | Therefore, we deduced that inflammation, from the histological point of view, is more correlated with cerebral circulation disorders than with coronary disease. | 21483163 |
| Communicable Diseases, Primary malignant neoplasm, Inflammation | Altered Intercellular Communication | Our data also indicate that, at least in this model, inflammation can predispose to retroviral infection and cancer. | 21483485 |
| Disease | Altered Intercellular Communication | Immune and inflammation-associated gene expression, in contrast, was more variable between models as compared to the human disease. | 21483750 |
| ARCN1 gene, Chronic Obstructive Airway Disease, Airway structure | Altered Intercellular Communication | Chronic obstructive pulmonary disease (COPD) is characterised by irreversible airflow obstruction, neutrophilic airway inflammation and chronic bacterial colonisation, however the role of the innate immune response in the pathogenesis of COPD remains unclear. | 21483784 |
| Malaria, Falciparum, Inflammation, Parasitemia | Altered Intercellular Communication | However, the reproducibility of those models is limited, with only a proportion of animals supporting longstanding parasitemia, due to strong inflammation induced by P. falciparum. | 21483851 |
| Malaria, Falciparum, Inflammation | Altered Intercellular Communication | We demonstrate here the role of aging, of inosine and of the IL-2 receptor g mutation in controlling P. falciparum induced inflammation. | 21483851 |
| Granulomatous inflammation, Infiltration | Altered Intercellular Communication | Contribution of T cell-mediated immunity is suggested by the presence of granulomatous inflammation and T cell infiltrates in different tissues. | 21484763 |
| Inflammation, Hyperlipidemia | Altered Intercellular Communication | BSS would further accelerate the chronic inflammation process of hyperlipidemia. | 21485068 |
| Hepatic inflammation, Ascites | Altered Intercellular Communication | Further analysis showed that internal accumulation of dampness-heat syndrome was characterized by obvious hepatic inflammation, poor synthesis function and more ascites. | 21486549 |
| Ascites | Altered Intercellular Communication | Liver-kidney yin deficiency syndrome was characterized by low-level hepatic inflammation, poor synthesis function and more ascites. | 21486549 |
| Avitaminosis, Hepatic inflammation, Ascites, Depression, CTCAE, Blood Stasis, Traumatic injury | Altered Intercellular Communication | Internal accumulation of blood stasis-heat syndrome was characterized by low-level hepatic inflammation, poorer synthesis function, ascites and splenomegalia, and liver depression and spleen deficiency syndrome was characterized by slight hepatic inflammation, synthesis function injury, decreased internal portal vein diameter and less ascites. | 21486549 |
| Inflammation, Deposition, Endothelial dysfunction, Obesity | Altered Intercellular Communication | Obesity is associated with endothelial dysfunction and increased inflammation as well as with expansion of the capillary bed in regional adipose deposits, and a balance between these factors is involved in angiogenesis. | 21486700 |
| Inflammation | Altered Intercellular Communication | Osteopontin (OPN) is a proinflammatory cytokine involved in regulating immune processes and mediating chronic inflammation. | 21486700 |
| Fibrosis Assessment, Non-alcoholic Fatty Liver Disease, Portal inflammation | Altered Intercellular Communication | Bile ductules positive for CK19 were increased along with the progression of staging and fibrosis of NAFLD, and the increased bile ductules were associated with portal inflammation and fibrosis. | 21486894 |
| Inflammation, Fibrosis Assessment | Altered Intercellular Communication | Such senescent bile ductules frequently express chemotactic protein, CCL2 (MCP-1), which may be responsible for chemoattraction of activated HSC around the bile ductules in portal and septal fibrosis and for portal inflammation. | 21486894 |
| Inflammation, Crohn Disease, melanoma, Lymphangiectasis, Malabsorption Syndrome, Enteritis | Altered Intercellular Communication | SBE diagnosed Crohn's disease in four patients, malabsorption syndromes in two, lymphangiectasia in two, eosinophilic enteritis in one, melanoma in one, and nonspecific inflammation in eight. | 21487872 |
| Manufactured sign, Precocious Puberty | Altered Intercellular Communication | Hormonal signs (precocious puberty, telarca, menarche) were common in younger patients and led to an early diagnosis. | 21488154 |
| Tissue damage, Inflammation, Thrombus, Thrombophilia | Altered Intercellular Communication | This hypercoagulability may contribute to inflammation, tissue damage and, possibly, thrombotic risk. | 21488867 |
| Inflammation, Atrial Fibrillation by ECG Finding | Altered Intercellular Communication | Impact of biomarkers of inflammation and extracellular matrix turnover on the outcome of atrial fibrillation ablation: importance of matrix metalloproteinase-2 as a predictor of atrial fibrillation recurrence. | 21489023 |
| Myocardial fibrosis, Atrial Fibrillation, Inflammation | Altered Intercellular Communication | AF is associated with inflammation and subsequent myocardial fibrosis. | 21489023 |
| Inflammation | Altered Intercellular Communication | Gastric cardiac-type mucosa with acute and chronic inflammation was documented on biopsy. | 21489041 |
| Inflammation | Altered Intercellular Communication | Thrombomodulin, which is expressed solely on monocytes, along with tissue factor (TF), takes part in coagulation and inflammation. | 21489300 |
| Inflammation | Altered Intercellular Communication | ISR lesions after drug-eluting stenting showed persistent signs of delayed or incomplete wound healing and relapsed inflammation, compared with BMS. | 21489821 |
| Inflammation, Spinal Diseases | Altered Intercellular Communication | Human neuropathological and animal model evidence supporting a role for Fas-mediated apoptosis and inflammation in cervical spondylotic myelopathy. | 21490053 |
| Inflammation, Traumatic, Spinal Cord Injuries, Spinal Diseases | Altered Intercellular Communication | Based on animal models of cervical spondylotic myelopathy and traumatic spinal cord injury, we hypothesized that Fas-mediated apoptosis and inflammation may play an important role in the pathobiology of human cervical spondylotic myelopathy. | 21490053 |
| Inflammation, Spinal Diseases | Altered Intercellular Communication | Our data demonstrate, for the first time in humans, the potential contribution of Fas-mediated cell death and inflammation to the pathobiology of cervical spondylotic myelopathy. | 21490053 |
| Inflammation, Stomach Neoplasms | Altered Intercellular Communication | Loss of TFF1 is associated with activation of NF-kB-mediated inflammation and gastric neoplasia in mice and humans. | 21490402 |
| Inflammation, Endothelial dysfunction, Autoimmune thyroiditis, Hypothyroidism | Altered Intercellular Communication | Endothelial dysfunction and low grade chronic inflammation in subclinical hypothyroidism due to autoimmune thyroiditis. | 21490407 |
| Inflammation, Endothelial dysfunction, Atherosclerosis, Hypothyroidism | Altered Intercellular Communication | Our study aims to investigate the presence of the well known preceding clinical situations of atherosclerosis like endothelial dysfunction and inflammation in subclinical hypothyroidism. | 21490407 |
| Saint Helena Islands, Inflammation, Endothelial dysfunction, Autoimmune thyroiditis | Altered Intercellular Communication | Our findings suggest that there is endothelial dysfunction and low grade chronic inflammation in SH due to autoimmune thyroiditis. | 21490407 |
| Inflammation | Altered Intercellular Communication | According to our results low grade chronic inflammation may be one of these factors. | 21490407 |
| Ischemia, Inflammation, Vascular System Injuries | Altered Intercellular Communication | In models of acute ischaemia, erythropoietin (EPO) administration has been found to attenuate vascular injury largely through reduced apoptosis, suppressed inflammation and increased nitric oxide availability. | 21492156 |
| Inflammation, Chronic pain | Altered Intercellular Communication | Patients have been given multiple courses of antibiotics even in the absence of identifiable organisms, anti-inflammatory drugs in the absence of proven inflammation, and narcotic analgesics in an attempt to control chronic pain. | 21492375 |
| Autoimmune Diseases, Lupus Erythematosus, Acute and chronic inflammation, Lupus Erythematosus, Systemic | Altered Intercellular Communication | Systemic lupus erythematosus (SLE) is an autoimmune disease with chronic or episodic inflammation in many different organ systems, activation of leukocytes and production of pro-inflammatory cytokines. | 21492422 |
| Inflammation, Lupus Erythematosus, Systemic | Altered Intercellular Communication | Patients with SLE had increased cell surface S100A8/A9, which could be important in amplification and persistence of inflammation. | 21492422 |
| Inflammation, Cerebral Aneurysm, Aneurysm | Altered Intercellular Communication | Polyglycolic-polylactic acid (PGLA) coils induce inflammation within a cerebral aneurysm, which in turn is hypothesized to decrease aneurysm recurrence. | 21492633 |
| Arterial Stiffness, Inflammation, HIV Infections | Altered Intercellular Communication | HIV disease is associated with increased arterial stiffness, which may be related to inflammation provoked by HIV-related immune perturbation. | 21492857 |
| Inflammation | Altered Intercellular Communication | Cryopyrin-associated periodic syndromes (CAPS) represent a spectrum of CIAS1 gene-mediated autoinflammatory diseases characterized by recurrent systemic inflammation. | 21493283 |
| Glomerulitis (disorder), Arteriosclerosis, Interstitial inflammation | Altered Intercellular Communication | Accelerated arteriosclerosis was significantly associated with peritubular capillary leukocytic infiltration, glomerulitis, subclinical antibody-mediated rejection, and interstitial inflammation. | 21493773 |
| Asthma, Myositis | Altered Intercellular Communication | Severe asthma is characterized by a dramatic increase in smooth muscle and airway inflammation. | 21493783 |
| Inflammation, Asthma | Altered Intercellular Communication | Taken together, these results highlight the ERK1/ERK2 MAPK cascade as a novel and attractive target in severe asthma because the activation of this pathway is insensitive to the action of glucocorticoids and is involved in neutrophil recruitment, contributing the to inflammation seen in the disease. | 21493783 |
| Hemangioma, Cavernous, Inflammation, Congenital arteriovenous malformation | Altered Intercellular Communication | Cavernomas and arteriovenous malformations are also sites of active inflammation. | 21493906 |
| Inflammation, Septic Shock | Altered Intercellular Communication | Circulating microparticles from septic shock patients exert differential tissue expression of enzymes related to inflammation and oxidative stress. | 21494101 |
| Leukoencephalopathy, Inflammation, Encephalitis | Altered Intercellular Communication | To control for the possibility that inflammation owing to other etiologies could result in EBV-positive cell accumulation, 11 brain biopsies of encephalitis and 4 brain biopsies of progressive multifocal leukoencephalopathy were also studied. | 21494180 |
| Inflammation, Discitis | Altered Intercellular Communication | Radical surgical debridement and appropriate antibiotic provide a reliable approach to achieve complete healing of the inflammation in cervical spondylodiscitis. | 21494200 |
| Takayasu Arteritis | Altered Intercellular Communication | Takayasu arteritis is an inflammatory condition that involves the large cardiac vessels, predominantly the aorta and its main branches. | 21494533 |
| Airway structure | Altered Intercellular Communication | Increased central sympathetic nerve activity induced by local airway inflammation may be one possible mechanism. | 21494635 |
| Airway structure | Altered Intercellular Communication | However, we can not exclude that chronic airway inflammation may contribute to sympathetic activation. | 21494635 |
| Arthralgia, Bothered by Vomiting | Altered Intercellular Communication | Three mild and transient adverse events (upper respiratory tract inflammation, arthralgia, and vomiting) were reported in the study. | 21494765 |
| Inflammation, Traumatic injury | Altered Intercellular Communication | At the same time, the present case demonstrated that it is very difficult to understand and predict changes in the inflammation process associated with children's facial trauma. | 21496202 |
| vascular inflammations, Fever | Altered Intercellular Communication | Kawasaki disease is an acute febrile disease of unknown etiology, characterized by systemic vascular inflammation involving the small and medium sized arteries, with a predilection for the coronary arteries. | 21496328 |
| Fibrosis Assessment, Hepatitis | Altered Intercellular Communication | Hepatic BAMBI is reduced in rodent models of liver inflammation and fibrosis. | 21496456 |
| Cyst, Inflammation | Altered Intercellular Communication | The SOTLPs appear to originate from the epithelial lining of the cyst and do not appear to be directly associated with inflammation. | 21496660 |
| Amyloidosis | Altered Intercellular Communication | Recurrent AA amyloidosis in a kidney transplant is rare, especially when the underlying inflammatory condition is controlled. | 21496981 |
| Duodenal Perforation, CTCAE, Inflammation | Altered Intercellular Communication | We managed a 31-y-old bedridden case with punched out duodenal perforation without inflammation, from which the tip of the PEG tube protruded. | 21497055 |
| TNF protein, human, Tumor necrosis, Becquerel, Lip and Oral Cavity Carcinoma | Altered Intercellular Communication | Betel quid (BQ) components induce the secretion of tumour necrosis factor-alpha (TNF-a) in oral keratinocytes, which promotes oral mucosal inflammation and oral cancer. | 21497332 |
| Inflammation, Chronic sinusitis, Craniosynostosis, Chronic disease | Altered Intercellular Communication | Chronic rhinosinusitis (CRS) is a heterogeneous chronic disease characterized by local inflammation of the sinonasal tissues. | 21497884 |
| Inflammation | Altered Intercellular Communication | Overproduction of CCL23 in NPs might contribute to the pathogenesis of eosinophilic CRSwNP through the recruitment of CCR1(+) inflammatory cells, including monocytes and macrophages, and the amplification of local inflammation. | 21497884 |
| Inflammation, Cardiovascular Diseases | Altered Intercellular Communication | We also propose that the post-translational modifications identified in CYP27A1 exemplify a general mechanism whereby oxidative stress and inflammation deleteriously affect protein function, contributing, for example, to cholesterol-rich lesions associated with age-related macular degeneration and cardiovascular disease. | 21498512 |
| Inflammation, Thrombosis | Altered Intercellular Communication | Inflammation might contribute to the development of stent thrombosis (ST). | 21498913 |
| Inflammation | Altered Intercellular Communication | Uric acid (UA) is a cardiovascular risk marker associated with oxidative stress and inflammation. | 21498925 |
| Atrial Fibrillation, Inflammation, Atrial Fibrillation by ECG Finding | Altered Intercellular Communication | Recently, atrial fibrillation (AF) has been associated with inflammation and oxidative stress. | 21498925 |
| Cardiomyopathies, Congenital heart disease, Congestive heart failure, Diabetes Mellitus, Coronary Artery Disease, Thyroid dysfunction, Respiration Disorders, Kidney Failure, Heart valve disease | Altered Intercellular Communication | We excluded subjects with coronary artery disease, congestive heart failure, diabetes, valvular heart disease, congenital heart disease, cardiomyopathy, renal failure, inflammatory conditions, thyroid dysfunction, respiratory diseases, and those who were taking drugs that affect UA metabolism (apart from diuretics). | 21498925 |
| Malnutrition | Altered Intercellular Communication | In elderly MHD patients, it was possible to achieve improvements in both malnutrition and chronic inflammatory conditions with AN69. | 21499075 |
| Tissue damage, Inflammation | Altered Intercellular Communication | No tissue damage, inflammation, lesions, and QDs deposition were found in histology and TEM images of the anti-HER2ab-QDs treated group. | 21499435 |
| Inflammation, Obstructive nephropathy due to prostatic hypertrophy | Altered Intercellular Communication | In this investigation, we study the relation between chronic inflammation of the tonsils, clinical features, and the presence of biofilms in the crypts in patients presenting with obstructive hypertrophy and recurrent upper airway pathology. | 21499955 |
| Inflammation, Thrombus | Altered Intercellular Communication | Circulating tissue factor (TF) is associated with inflammation and may contribute to thrombotic events. | 21500176 |
| Giant cell sarcoma, Hodgkin Disease | Altered Intercellular Communication | FNA, core needle biopsy, and even small incisional biopsies may result in misdiagnosis of IMTDE as pleomorphic sarcoma, an inflammatory condition or even Hodgkin's disease. | 21500374 |
| Inflammation, Fatty degeneration | Altered Intercellular Communication | Inflammation is one mechanism that may link myosteatosis with increased T2DM risk, but studies examining the relationship between inflammation and myosteatosis are lacking. | 21501070 |
| Heredity, Inflammation | Altered Intercellular Communication | Our findings suggest that heredity may play a significant role in the determination of several markers of inflammation in African ancestry individuals. | 21501070 |
| Inflammation, Demyelination, Axonal loss, Degenerative disorder, Failure (biologic function) | Altered Intercellular Communication | Multiple sclerosis (MS) is a chronic progressive degenerative disorder of the central nervous system, characterized by inflammation, demyelination, ultimate failure of remyelination and axonal loss. | 21501208 |
| Inflammation, Carcinogenesis | Altered Intercellular Communication | Chronic inflammation is related to oxidative stress and is still believed to be the cause of carcinogenesis. | 21501233 |
| Cyst, Inflammation | Altered Intercellular Communication | Furthermore, cyst development is accompanied by chronic inflammation. | 21501233 |
| Inflammation, Ulcerative Colitis | Altered Intercellular Communication | Neutrophils in colonic mucosal tissue of patients with ulcerative colitis were the main cellular source of PTX3 protein, the expression of which is correlated well with the histological grades of inflammation. | 21501295 |
| Inflammation | Altered Intercellular Communication | Immunohistochemistry revealed that type IV collagen around capillaries in the area of the PCH without inflammation disappeared in the area with inflammation. | 21501297 |
| Inflammation | Altered Intercellular Communication | Obesity-associated macrophage infiltration into adipose tissue is responsible for both local and systemic inflammation. | 21501656 |
| Diabetes Mellitus, Non-Insulin-Dependent, Carcinogenesis, Hepatitis | Altered Intercellular Communication | Type 2 diabetes (T2DM) is associated with liver inflammation and carcinogenesis. | 21501980 |
| Inflammation, Secondary malignant neoplasm of liver, Pregnancy Complications, Infectious | Altered Intercellular Communication | Preoperative systemic inflammation and infectious complications after resection of colorectal liver metastases. | 21502458 |
| Inflammation, Secondary malignant neoplasm of liver, Pregnancy Complications, Infectious | Altered Intercellular Communication | To examine the association of postoperative infectious complications with preoperative systemic inflammation and survival in patients undergoing resection of colorectal liver metastases. | 21502458 |
| Chlamydia trachomatis, Upper Respiratory Infections | Altered Intercellular Communication | Nevertheless, chlamydial agents (C. trachomatis in infants, C. pneumoniae in pre-school children) should be taken into consideration in a differential diagnosis of respiratory tract inflammation. | 21503738 |
| Inflammation, Data types - Address, Nerve Degeneration | Altered Intercellular Communication | Among the pathogenic mechanisms in AD, chronic systemic inflammation is described and characterized by massive production of proinflammatory cytokines by peripheral blood mononuclear cells (PBMCs), which may contribute to an altered immune response and exacerbation of neurodegeneration. | 21504114 |
| Airway structure, Asthma, Bronchial Hyperreactivity | Altered Intercellular Communication | Comparison of bronchial hyperresponsiveness to methacholine and adenosine and airway inflammation markers in patients with suspected asthma. | 21504347 |
| Bronchitis | Altered Intercellular Communication | Indirect stimuli provide a better reflection of bronchial inflammation. | 21504347 |
| Metatarsophalangeal joint structure | Altered Intercellular Communication | US finding indicative of metatarsophalangeal joint inflammation were obtained in 77 (76.2%) patients, while only 34 (33.7%) patients were positive to the clinical examination. | 21504659 |
| Chronic dacryocystitis, Chronic infectious disease, Inflammation | Altered Intercellular Communication | Chronic dacryocystitis results in chronic infection and inflammation of the lacrimal sac. | 21505526 |
| Cataract, Pain Distress Question, Acute inflammation, Tissue damage | Altered Intercellular Communication | Small incisions in cataract surgery have shown to reduce tissue damage, postoperative inflammation and pain. | 21505539 |
| Inflammation | Altered Intercellular Communication | No cases of postoperative hypotony and increased inflammation were observed. | 21505539 |
| ARCN1 gene, Inflammation, Atherosclerosis | Altered Intercellular Communication | Although systemic inflammation plays the leading role in atherothrombotic processes, platelet activation and increased coagulation together with oxidative stress can significantly exacerbate atherosclerosis in COPD patients. | 21506665 |
| Inflammation | Altered Intercellular Communication | The presence of systemic inflammation was clearly proved by the increase in classical inflammatory markers (CRP, WBC and segmented neutrophil count). | 21506665 |
| Presenile dementia, Inflammation | Altered Intercellular Communication | Mean plaques scores and extent of gingival inflammation were higher for residents in the DD and D subgroups and resident with dementia. | 21507056 |
| Gingivitis, Dental Plaque | Altered Intercellular Communication | Residents assisted with brushing had higher mean plaque score and more moderate gingival inflammation. | 21507056 |
| Kidney Failure, Chronic, Inflammation | Altered Intercellular Communication | Patients with end-stage renal disease are prone to inflammation and inflammation is related to erythropoietin-stimulating agent hyporesponsiveness and mortality in this population. | 21507195 |
| Inflammation, Anemia | Altered Intercellular Communication | In this retrospective analysis, we determined whether the use of statins improves inflammation and inflammation-related anemia in a cohort of hemodialysis patients. | 21507195 |
| Carcinoma of larynx, Inflammation, Mutagenicity Tests | Altered Intercellular Communication | Bile acids in reflux material accumulate in the laryngeal tissue in laryngeal carcinoma patients; therefore, bile acids should be considered a carcinogenic factor in the etiology of laryngeal carcinoma because of their mutagenicity due to DNA breaking, as they cause chronic inflammation due to intracellular accumulation. | 21508656 |
| Inflammation, Chronic Obstructive Airway Disease, Chronic Kidney Diseases | Altered Intercellular Communication | There is some evidence that chronic obstructive pulmonary disease and chronic kidney disease (CKD) may be related, perhaps through systemic inflammation, which is common to both. | 21509480 |
| Inflammation | Altered Intercellular Communication | Analysis of synovial fluid in knee joint of osteoarthritis:5 proteome patterns of joint inflammation based on matrix-assisted laser desorption/ionization time-of-flight mass spectrometry. | 21509578 |
| Inflammation, Varicose, Edema, Pain Distress Question | Altered Intercellular Communication | The VCSS of varicose, edema, pigmentation, and inflammation were significantly reduced after both EVL and CHIVA; however, patients treated by EVL had significantly more pain postoperatively than those treated by CHIVA (p=0.003). | 21509638 |
| Inflammation, Retinitis Pigmentosa, Chondritis of pinna, polychondritis | Altered Intercellular Communication | Bilateral auricularis and nasal root inflammation, with auricular perichondritis positive for anti-type II collagen (CII) antibody, led to a diagnosis of relapsing polychondritis (RP). | 21509650 |
| Inflammation, Hypertension, CTCAE | Altered Intercellular Communication | The state of lipid metabolism, parameters of the oxidant system and inflammation markers were determined in healthy people (n = 30) and patients with hypertension (n = 132) of 60-74 years old. | 21510081 |
| Inflammation, Dental Plaque, Atherosclerosis | Altered Intercellular Communication | Inflammation, neovascularization and intra-plaque hemorrhage are associated with increased reparative collagen content: implication for plaque progression in diabetic atherosclerosis. | 21511672 |
| Inflammation, Plaque, Atherosclerotic | Altered Intercellular Communication | Sustained inflammation may stimulate a reparative process increasing early reparative type III collagen synthesis, promoting atherosclerotic plaque progression. | 21511672 |
| Inflammation, Demographics Domain, Diabetes Mellitus | Altered Intercellular Communication | We evaluated inflammation, neovascularization, intra-plaque hemorrhage (IPH), and collagen deposition in human aortic atherosclerotic plaques from patients with and without diabetes mellitus (DM). | 21511672 |
| Inflammation, Fibrous | Altered Intercellular Communication | In non-DM plaques, 27%, 40%, and 33% had mild, moderate and severe inflammation in the fibrous cap and shoulder compared with 2%, 30% and 68% in DM plaques (p < 0.001). | 21511672 |
| Inflammation | Altered Intercellular Communication | In conclusion, our study suggests that enhanced type III collagen deposition was associated with inflammation, neovascularization and IPH, and may be a contributing factor in DM plaque progression. | 21511672 |
| Inflammation, Traumatic injury, Myocarditis, CTCAE 5.0 | Altered Intercellular Communication | Cardiac MRI (CMRI) provides a comprehensive assessment of myocardial function, inflammation and injury in a single examination and has shown value in the diagnosis of myocarditis. | 21511746 |
| Inflammation, Fibrosis Assessment | Altered Intercellular Communication | Baseline levels of plasma biomarkers of inflammation and fibrosis significantly correlated with baseline eGFR but did not predict response to therapy. | 21511828 |
| Cessation of life, Dyslipidemias, atherosclerotic | Altered Intercellular Communication | In this hemodialysis cohort, dyslipidemia was associated with increased risk of incident atherosclerotic CVD, and protein energy wasting/inflammation with increased risk of death after CVD events. | 21511840 |
| Inflammation | Altered Intercellular Communication | [Specific features of the development of chronic inflammation in the maxillary sinus]. | 21512475 |
| Cholangiolitis, Inflammation | Altered Intercellular Communication | Cholangiolitis, inflammation of the cholangioles, is difficult to diagnose by conventional imaging modalities. | 21512668 |
| Malignant tumor of colon, Inflammation, Mucinous, Mucinous Adenocarcinoma | Altered Intercellular Communication | To determine whether contrast-enhanced ultrasonography (CEUS) can be used to discriminate between colon cancer and acute inflammation, and between mucinous and non-mucinous carcinoma. | 21512723 |
| Malignant tumor of colon, Inflammation | Altered Intercellular Communication | CEUS (with perflubutane microbubbles) was performed in two study groups: colon cancer (n = 34) and acute inflammation (n = 14). | 21512723 |
| Malignant tumor of colon, Inflammation | Altered Intercellular Communication | Differentiation between colon cancer and acute inflammation is possible with CEUS. | 21512723 |
| Malignant tumor of colon | Altered Intercellular Communication | The vascular structure was irregular in 76.5% of colon cancers but only 28.6% of acute inflammations (P < 0.01). | 21512723 |
| Malignant tumor of colon | Altered Intercellular Communication | Both abnormalities were found in 58.8% of colon cancers but in none of the acute inflammations. | 21512723 |
| Mycobacterium Infections, Granulomatous inflammation, Necrosis | Altered Intercellular Communication | Twenty-one patients with mycobacterial infection had available biopsy or surgical specimens for histopathologic examination and 16 (76.2%) specimens had pathologic features (granulomatous inflammation, caseating necrosis, or acid-fast bacilli) consistent with mycobacterial infection. | 21513844 |
| Dermatitis, Atopic, Superinfection, Data types - Address, Dermatitis | Altered Intercellular Communication | Staphylococcus aureus superinfections occur in more than 90% of patients with atopic dermatitis (AD) and aggravate skin inflammation. | 21513970 |
| Tissue damage, Dermatitis | Altered Intercellular Communication | S aureus toxins lead to tissue damage and augment T-cell-mediated skin inflammation by a superantigen effect. | 21513970 |
| Data types - Address | Altered Intercellular Communication | Evidence is provided that specific humoral and cellular immune responses to S aureus antigens dependent on antigen presentation represent a novel mechanism for S aureus-induced skin inflammation in AD. | 21513970 |
| Inflammation, Dyslipidemias, atherosclerotic, Obesity | Altered Intercellular Communication | Obesity related dyslipidemia, chronic inflammation and oxidative stress were associated with atherosclerotic sequels. | 21515245 |
| Inflammation | Altered Intercellular Communication | The accumulation of senescent stromal cells in aging tissue changes the local microenvironment from normal to a state similar to chronic inflammation. | 21515933 |
| Gingivitis, Hemorrhage, Dental Plaque | Altered Intercellular Communication | Clinical assessments of dental implants and contralateral natural teeth included dental plaque, gingival inflammation, and bleeding on probing. | 21516280 |
| Communicable Diseases, Inflammation, Gastritis | Altered Intercellular Communication | The aim of the work was to study the relationship between structural changes in gastric mucosa affected by atrophic gastritis and inflammation associated with Hp infection. | 21516763 |
| Inflammation, Pathology | Altered Intercellular Communication | Endoscopic examination and NBI-visualization were used to assess distribution and severity of inflammation in 500 patients with different gastric pathologies. | 21516763 |
| Inflammation, Atrophic | Altered Intercellular Communication | Mucosal changes characteristic of atrophy were only rarely accompanied by marked inflammation (14.8%) and were either mild (21%) or moderately severe (64.2%). | 21516763 |
| Gastric mucosa, Inflammation, Gastritis, Atrophic | Altered Intercellular Communication | It suggests that atrophy of gastric mucosa should be regarded as independent condition while the term atrophic gastritis should be used only in case of association between atrophy and inflammation confirmed by microscopic studies. | 21516763 |
| Inflammation | Altered Intercellular Communication | Endoscopic ligation of the esophageal veins did not change the rate of EM inflammation detection. | 21516841 |
| Inflammation | Altered Intercellular Communication | This is evidence that IL-6 in the urine had a local origin (intrarenal), reflecting activity of immune inflammation in the kidney. | 21516850 |
| Postprandial Period, Diabetes Mellitus, Non-Insulin-Dependent | Altered Intercellular Communication | Effects of mealtime insulin aspart and bedtime NPH insulin on postprandial inflammation and endothelial cell function in patients with type 2 diabetes. | 21518259 |
| Inflammation, Endothelial dysfunction, Hyperglycemia | Altered Intercellular Communication | We suggested that rapid-acting insulin has a beneficial postprandial effect on endothelial dysfunction and inflammation compared with intermediate-acting insulin because of its ability to lower postprandial hyperglycaemia. | 21518259 |
| Lymphoproliferative Disorders | Altered Intercellular Communication | Our data suggests that PL may represent an inflammatory condition induced by various triggering agents, such as HHV-8, rather than a lymphoproliferative disorder. | 21518386 |
| Inflammation, Diabetes Mellitus | Altered Intercellular Communication | Serum hs-CRP levels could predict the incidence of diabetes, indicating that inflammation might have great importance in the onset of diabetes. | 21518530 |
| Inflammation, Prostate carcinoma | Altered Intercellular Communication | Inflammation may be involved in prostate cancer development and progression. | 21518693 |
| Inflammation, Drug-induced, leukemia, Neoplasms | Altered Intercellular Communication | Enlargement can be of many types depending on etiologic factors like inflammation, drug-induced effects, neoplasm, hormonal imbalance, and systemic involvement (leukemia, etc). | 21519587 |
| Inflammation, Drug-induced, leukemia, Neoplasms | Altered Intercellular Communication | Enlargement can be of many types depending on etiologic factors like inflammation, drug-induced effects, neoplasm, hormonal imbalance, and systemic involvement (leukemia, etc). | 21519587 |
| Inflammation, Dental caries, Osteopenia | Altered Intercellular Communication | Occasionally dental caries could compromise the interproximal contact point, leading to migration of the adjacent teeth with consequent retention of food, gingival inflammation, pocket formation, bone loss and dental mobility. | 21519654 |
| Inflammation | Altered Intercellular Communication | Visceral adipose tissue may fuel obesity-associated chronic inflammation and tumorigenesis. | 21520028 |
| Inflammation, Primary malignant neoplasm | Altered Intercellular Communication | T cells may be important in visceral adipose tissue in driving inflammation, but they have not yet been characterized in patients with cancer. | 21520028 |
| Inflammation | Altered Intercellular Communication | It may fuel chronic inflammation via T cell-mediated pathways. | 21520028 |
| Inflammation, Prostate carcinoma, Malignant Neoplasms | Altered Intercellular Communication | Androgens and inflammation have been implicated in the etiology of several cancers, including prostate cancer. | 21520164 |
| Inflammation, Chronic Kidney Diseases | Altered Intercellular Communication | High plasma retinol binding protein 4 (RBP4) is associated with systemic inflammation independently of low RBP4 adipose expression and is normalized by transplantation in nonobese, nondiabetic patients with chronic kidney disease. | 21521262 |
| Inflammation, Obesity, Diabetes Mellitus | Altered Intercellular Communication | Potential involvement of plasma and adipose RBP4 in systemic inflammation in the absence of obesity and diabetes is unknown. | 21521262 |
| Renal Insufficiency, Chronic Kidney Diseases | Altered Intercellular Communication | Inflammation reduces survival in chronic kidney disease (CKD) [particularly in maintenance haemodialysis (MHD)], and plasma RBP4 may increase with renal dysfunction. | 21521262 |
| Inflammation, Chronic Kidney Diseases | Altered Intercellular Communication | We investigated (i) potential associations between RBP4 and inflammation in CKD and (ii) the role of adipose tissue in this putative interaction. | 21521262 |
| Inflammation, Obesity, Chronic Kidney Diseases, Diabetes Mellitus | Altered Intercellular Communication | High plasma RBP4 and inflammation are clustered in CKD in the absence of obesity and diabetes and are normalized by transplantation. | 21521262 |
| Inflammation | Altered Intercellular Communication | Cardiopulmonary bypass (CPB) and cardiac surgery cause an inflammatory response, as measurable by an increase in the concentration of C-reactive protein (CRP), a nonspecific inflammation marker. | 21521673 |
| Inflammation, Abnormality of mitochondrial metabolism, Hypoxia, Neoplasms | Altered Intercellular Communication | Gene set enrichment analysis (GSEA) revealed "stemness," inflammation, DNA damage, aging, oxidative stress, hypoxia, autophagy and mitochondrial dysfunction in the tumor stroma of patients lacking stromal Cav-1. | 21521946 |
| Granulomatous inflammation, Malignant Neoplasms | Altered Intercellular Communication | Breast malignancy or granulomatous inflammation could not be excluded. | 21522109 |
| Granulomatous Cheilitis | Altered Intercellular Communication | Granulomatous cheilitis is a rare granulomatous inflammation of the lips of unknown origin; mainly young adults are affected. | 21523519 |
| Diverticulum, Hemorrhage, Intussusception, Perforation (observation) | Altered Intercellular Communication | The diverticulum complication generated: occlusion--43.7% (n = 15), inflammation--37.5% (n = 12), bleeding, two cases of diverticulum tumor, an intussusception case and a perforation case with unknown object. | 21523959 |
| Inflammation, Anemia | Altered Intercellular Communication | The main type of anemia present among women 18-49 years old was IDA (61% of anemia cases) while anemic women 50 years and over suffered mainly from anemia related to chronic inflammation (ACI) (42%). | 21524361 |
| Inflammation, Hypertensive (finding) | Altered Intercellular Communication | These results suggest inflammation, as measured by hs-CRP level, is associated with carotid artery IMT among hypertensive adults rather than other traditional risk factors. | 21524639 |
| Inflammation | Altered Intercellular Communication | RHR was associated with markers of chronic low-grade inflammation. | 21525123 |
| Inflammation, Critical Illness | Altered Intercellular Communication | A comparison of zinc metabolism, inflammation, and disease severity in critically ill infected and noninfected adults early after intensive care unit admission. | 21525204 |
| Inflammation, Hyperglycemia | Altered Intercellular Communication | These data highlight the importance of diet composition in the treatment and prevention of inflammation and hyperglycemia. | 21525252 |
| Inflammation | Altered Intercellular Communication | These patients are on maintenance hemodialysis where they are exposed to dialysis fluid and dialysis membrane that generate an acute-phase response, which leads to inflammation, reflected in increased inflammatory markers like C-reactive protein (CRP) and interleukin-6 (IL-6). | 21525578 |
| Neoplasms | Altered Intercellular Communication | Recent evidence suggests that the chemokine axis of CXC chemokine ligand-12 and its receptor CXC chemokine receptor-4 (CXCL12/CXCR4) is highly expressed in gynecological tumors and the axis of CXC chemokine ligand-16 and CXC chemokine receptor-6 (CXCL16/CXCR6) is overexpressed in inflammation-associated tumors. | 21527066 |
| Inflammation, Diabetes Mellitus, Non-Insulin-Dependent | Altered Intercellular Communication | The fixed combination of pioglitazone and metformin improves biomarkers of platelet function and chronic inflammation in type 2 diabetes patients: results from the PIOfix study. | 21527115 |
| Inflammation, Sarcopenia, Malnutrition, Chronic disease | Altered Intercellular Communication | The causes of sarcopenia are multifactorial and can include disuse, altered endocrine function, chronic diseases, inflammation, insulin resistance, and nutritional deficiencies. | 21527165 |
| Inflammation, Edema | Altered Intercellular Communication | When comparing groups 1 and 2, there was no statistically significant difference in inflammation and edema. | 21527192 |
| Inflammation, Melanosis, Non-Malignant | Altered Intercellular Communication | We retrospectively reviewed all non-malignant colon mucosal biopsies between 2005 and 2007, reported as normal, chronic inflammation or melanosis coli in patients who were undergoing routine colonoscopy. | 21528078 |
| Inflammation | Altered Intercellular Communication | The sustained release of large quantities of autologous growth factors, cytokines, and other mediators found in PRP plus the favorable mononuclear cell profile of PRP may help us to stimulate wound healing and resolve chronic inflammation. | 21528636 |
| Inflammation, Ear Inflammation | Altered Intercellular Communication | The only adverse reactions were episodic inflammations of the upper and/or lower respiratory tract, but there was no otitis. | 21528770 |
| Inflammation, Carcinogenesis, Chronic disease | Altered Intercellular Communication | Oxidative stress and inflammation are constant features of many chronic diseases and complications, and have been linked to carcinogenesis. | 21530094 |
| Airway structure, ARCN1 gene, Chronic Obstructive Airway Disease | Altered Intercellular Communication | Although there is widespread interest in fractional exhaled nitric oxide (FeNO) as a non-invasive, time and cost effective biomarker for assessing airway inflammation in chronic obstructive pulmonary disease (COPD), its usefulness is still controversial. | 21530214 |
| Inflammation, Cardiac fibrosis, Hypertension, CTCAE | Altered Intercellular Communication | Hypertension causes cardiac fibrosis characterized by low-grade inflammation. | 21530504 |
| Airway structure, Asthma, Eosinophilic inflammation | Altered Intercellular Communication | Fractional exhaled nitric oxide (FeNO) measurement is an index of airway eosinophilic inflammation and is primarily employed to diagnose bronchial asthma and assess airway inflammation. | 21530868 |
| Inflammation, Dysplasia, Malignant neoplasm of gastrointestinal tract, Neoplasms | Altered Intercellular Communication | The frequency of HLTF methylation in high grade dysplasia and GCA tumor tissues was significantly higher than that in chronic inflammation tissues and was significantly associated with upper gastrointestinal cancers (UGIC) family history and protein and mRNA expression of the gene. | 21531217 |
| Inflammation, Dysplasia | Altered Intercellular Communication | HLTF methylation was not found in the plasma of patients with chronic inflammation and low grade dysplasia, while 4.0% (1/25) of patients with high grade dysplasia and 20.8% of (20/96) GCA patients were detected with hypermethylation of HLTF in the plasma. | 21531217 |
| Inflammation, Peritonitis | Altered Intercellular Communication | In univariate analysis, baseline PAD, peritonitis during follow-up, inflammation (C-reactive protein), serum uric acid, CaxP, and serum phosphate were all significantly associated with a greater-than-50% decrease in RRF during follow-up. | 21532004 |
| Inflammation, Infection of bloodstream, Critical Illness | Altered Intercellular Communication | Red cell distribution width is a robust predictor of the risk of all-cause patient mortality and bloodstream infection in the critically ill. Red cell distribution width is commonly measured, inexpensive, and widely available and may reflect overall inflammation, oxidative stress, or arterial underfilling in the critically ill. | 21532476 |
| Inflammation | Altered Intercellular Communication | Cytokines such as interleukin 10 (IL10) may play an important role in the process of inflammation. | 21532858 |
| Inflammation, Necrosis, Fibrosis Assessment, Metaplasia, Hyperplasia | Altered Intercellular Communication | Direct correlation was seen between tendon and bursal hyperplasia and time of the onset of symptoms; between tendon chondral metaplasia, fibrosis, bursal neoangiogenesis, inflammation, and patient age; between tendon neoangiogenesis, hyperplasia, necrosis, fibrosis, bursal necrosis, inflammation, and lesion size; on the contrary, tendon fibrosis, necrosis, and bursal tissue inflammation decrease as time passes from the onset of symptoms. | 21533534 |
| Inflammation | Altered Intercellular Communication | Tendon fibers disarray, neoangiogenesis, and inflammation decreases as the patient's age increases. | 21533534 |
| Inflammation | Altered Intercellular Communication | Consequently, the patient recovered gradually from the inflammation and underwent CABG as scheduled 28 days later. | 21533587 |
| Tubercular | Altered Intercellular Communication | Unilateral obstruction of the foramen of Monro due to chronic tubercular ependymal inflammation was suspected and endoscopic septostomy was planned. | 21534211 |
| Inflammation, hepcidin, Anemia | Altered Intercellular Communication | IL6 and hepcidin levels did not differ significantly between AUE and control groups, indicating that inflammation or iron restriction is not central feature of anaemia in this group. | 21535154 |
| Inflammation, Endothelial dysfunction | Altered Intercellular Communication | After additional adjustment for markers of inflammation and endothelial dysfunction, the association was attenuated (HR 1.50; 95% CI, 1.08-2.09). | 21535251 |
| Inflammation, MS gene, Nerve Degeneration | Altered Intercellular Communication | Literature includes evidence of initial predominance of inflammation and later development of neurodegeneration in the pathogenesis of multiple sclerosis (MS). | 21535941 |
| Immunologic Deficiency Syndromes, Inflammation | Altered Intercellular Communication | Inflammation in common variable immunodeficiency is associated with a distinct CD8(+) response to cytomegalovirus. | 21536322 |
| Inflammation | Altered Intercellular Communication | This complication necessitated a first exploratory and cleansing surgery, as well as a second surgery, which clarified the origin of the inflammation and made it possible to eliminate the wax remains. | 21536361 |
| Corneal Neovascularization | Altered Intercellular Communication | Similarly, in a model of inflammation-induced corneal neovascularization, young TSP-1-deficient mice develop exacerbated lymphangiogenesis, which can be reversed by topical application of recombinant human TSP-1. | 21536744 |
| Inflammation | Altered Intercellular Communication | Patients had critically colonised and/or infected, malodorous wounds, covered with slough/fibrin or wounds showing inflammation of the periwound skin. | 21537301 |
| Inflammation, Pain Distress Question | Altered Intercellular Communication | Inflammation was reduced in 60% (n=44) of cases and patients did not report pain or discomfort when using AM. | 21537301 |
| Inflammatory disease of mucous membrane, Irritable Bowel Syndrome | Altered Intercellular Communication | Recent studies support the hypothesis that postinfectious irritable bowel syndrome and some irritable bowel syndrome patients display persistent signs of minor mucosal inflammation. | 21537540 |
| Inflammation | Altered Intercellular Communication | By comparing the different types of isolated bacterial strains with the interleukin -8 (-251) and the histopathological data we observed that carriers of the A allele (AT and AA) infected by virulent strains (m1s1 cagA+) demonstrated a greater risk of presenting a degree of inflammation (OR = 24.75 CI 95% 2.29-267.20 P = 0.004) and increased neutrophilic activity (OR = 28.71 CI 95% 2.62-314 P = 0.002) in the gastric mucosa. | 21537542 |
| Infection caused by Helicobacter pylori | Altered Intercellular Communication | Our findings suggest that aberrant AID expression is correlated with persistent inflammatory condition induced by H. pylori infection and may contribute to the development of GC through an inflammatory condition and intestinalization. | 21538122 |
| Infarction, Inflammation | Altered Intercellular Communication | In conclusion, the TLR4 pathway is activated after MI and correlates with infarct severity but not with the extent of inflammation. | 21538184 |
| Inflammation, Esophageal carcinoma | Altered Intercellular Communication | Evidence is increasing that elevated systemic inflammation is associated with poor survival in patients with oesophageal carcinoma. | 21538187 |
| Malignant neoplasm of esophagus, Inflammation | Altered Intercellular Communication | The aim of the present study was to compare the predictive value of selected markers of systemic inflammation in patients who undergo surgical resection of oesophageal cancer. | 21538187 |
| Inflammation, Primary malignant neoplasm, Esophageal carcinoma | Altered Intercellular Communication | The present study indicates that the mGPS, an acute-phase protein-based prognostic score, better predicts cancer survival compared with the cellular components of systemic inflammation in patients with oesophageal carcinoma. | 21538187 |
| Degenerative polyarthritis, Inflammation, Pain Distress Question | Altered Intercellular Communication | Increased inflammation and pain are inseparable parts of knee osteoarthritis (OA) that may lead to disuse of the affected limb. | 21538317 |
| Degenerative polyarthritis, Inflammation, Atrophic, Myositis | Altered Intercellular Communication | Gene expression and the protein abundance of numerous muscle markers of inflammation and atrophy were elevated in patients with knee OA, and the increase in muscle inflammation was associated with a reduction in muscle strength. | 21538317 |
| Inflammation, Rhabdomyositis, Atrophic | Altered Intercellular Communication | Given the role inflammation markers may play in muscle strength and atrophy, further studies are needed to investigate the effect of exercise intervention on skeletal muscle inflammation. | 21538317 |
| Inflammation, Sample Size Calculation, Endothelial dysfunction, Atherosclerosis | Altered Intercellular Communication | Endothelial dysfunction and inflammation are pathogenic mechanisms common to systemic sclerosis (SSc) and atherosclerosis. | 21538320 |
| Inflammation, Vascular Diseases, Chronic Kidney Diseases | Altered Intercellular Communication | Insulin resistance, inflammation, and vascular disease in nondiabetic predialysis chronic kidney disease patients. | 21538390 |
| Cardiovascular morbidity, Inflammation, Chronic Kidney Diseases | Altered Intercellular Communication | Chronic kidney disease (CKD) is associated with high cardiovascular morbidity and mortality, which is not fully explained by traditional risk factors; hence, the interest in nontraditional risk factors such as inflammation and insulin resistance (IR). | 21538390 |
| Vascular Diseases, Inflammation, Chronic Kidney Diseases | Altered Intercellular Communication | Though IR is shown in nondiabetic CKD, its association with vascular disease and inflammation in this population is unknown, and is what this study aims to investigate. | 21538390 |
| Inflammation, Vascular Diseases, Chronic Kidney Diseases | Altered Intercellular Communication | IR and inflammation are related to vascular disease in nondiabetic predialysis CKD patients. | 21538390 |
| Inflammation, Endothelial dysfunction, Chronic Kidney Diseases, Atherosclerosis | Altered Intercellular Communication | Subjects with systemic inflammation were more insulin-resistant, and in nondiabetic predialysis CKD, IR and systemic inflammation were independently associated with endothelial dysfunction and atherosclerosis. | 21538390 |
| Inflammation, Necrosis, Granulation finding, Ulcer | Altered Intercellular Communication | DESIGN is a seven-item (depth, exudates, size, inflammation/infection, granulation, necrosis, and pocket) monitoring scale for pressure ulcers developed in 2002 by the scientific education committee of the Japanese Society of Pressure Ulcers. | 21539648 |
| Inflammation, Exudate, Necrosis | Altered Intercellular Communication | Weighting (-b value) for each item in order of the highest rank was: pocket, 2.289; size, 1.573; inflammation/infection, 0.778; granulation tissue, 0.682; exudate, 0.543; and necrotic tissue, 0.529. | 21539648 |
| Cessation of life, Hepatorenal Syndrome, Pneumonitis | Altered Intercellular Communication | Four deaths (15.4%) occurred: 3 due to perioperative progressing pulmonary infection/inflammation and 1 due to hepatorenal failure. | 21540614 |
| Angioedema, Bothered by Vomiting, Asthenia, Anemia, Nausea, Inflammatory disease of mucous membrane | Altered Intercellular Communication | Cilengitide-related grade 3/4 AEs, all of which occurred after the DLT observation period, were anaemia, angioedema, asthenia, mucosal inflammation, nausea and vomiting (one event per category). | 21540865 |
| Inflammation, Coronary Arteriosclerosis | Altered Intercellular Communication | MRP8/14 is associated with systemic inflammation in stable coronary atherosclerosis in men. | 21542848 |
| Inflammation | Altered Intercellular Communication | The phagocyte activation marker MRP8/14 is significantly associated with markers of systemic inflammation in male patients with CAD. | 21542848 |
| Hypothalamic structure | Altered Intercellular Communication | Intake of trans fatty acids during gestation and lactation leads to hypothalamic inflammation via TLR4/NFkBp65 signaling in adult offspring. | 21543208 |
| Obesity, Hypothalamic structure | Altered Intercellular Communication | Thus, the present study shows that the mothers' hydrogenated vegetable fat intake during pregnancy and lactation led to hypothalamic inflammation and impaired satiety-sensing, which promotes deleterious metabolic consequences such as obesity, even after the withdrawal of the causal factor. | 21543208 |
| Inflammation, Atrial Fibrillation by ECG Finding | Altered Intercellular Communication | N-3 polyunsaturated fatty acids administration does not reduce the recurrence rates of atrial fibrillation and inflammation after electrical cardioversion: a prospective randomized study. | 21543294 |
| Inflammation, Atrial Fibrillation by ECG Finding | Altered Intercellular Communication | N-3 polyunsaturated fatty acids administration does not reduce the recurrence rates of atrial fibrillation and inflammation. | 21543294 |
| Ischemia, Inflammation | Altered Intercellular Communication | Remote intermittent ischemia before coronary artery bypass graft surgery: a strategy to reduce injury and inflammation? | 21544683 |
| Venous stenosis, Inflammation, Cardiac Arrhythmia, teratologic | Altered Intercellular Communication | The risk factors are as follows: inflammation or injury, vein anomalies, arrhythmia, venous stenosis. | 21544979 |
| Airway structure, Smoking | Altered Intercellular Communication | Smoking is thought to modify the pattern of airway inflammation. | 21545371 |
| Narcolepsy, Sleep Disorders | Altered Intercellular Communication | These sleep problems partly resemble core symptoms of narcolepsy, a sleep disorder caused by a general loss of the neurotransmitter hypocretin. | 21546124 |
| Airway structure, Asthma | Altered Intercellular Communication | Expiratory flows and airway inflammation in elderly asthmatic patients. | 21546232 |
| Airway structure, Asthma | Altered Intercellular Communication | We aimed to compare lung function and airway inflammation in elderly and younger asthmatic subjects. | 21546232 |
| Inflammation | Altered Intercellular Communication | Ongoing inflammation is associated with elevated levels of beta 2 microglobulin (B2M). | 21546482 |
| Electrocardiogram: myocardial infarction (finding), Arteritis | Altered Intercellular Communication | Coronary artery inflammation is a critical process in the pathogenesis of myocardial infarction (MI). | 21547257 |
| Encephalitis, Neurologic Deficits, Inflammation, Psychiatric | Altered Intercellular Communication | Consecutive children presenting over a 12-month period with newly acquired psychiatric and/or neurologic deficits consistent with anti-NMDAR encephalitis and evidence of central nervous system (CNS) inflammation were screened. | 21547896 |
| Inflammation, Complication Aspects | Altered Intercellular Communication | Application of the puncture-drainage interventions under ultrasonographic control, as well as lumbotomy and sequestrectomy, in the environment of aseptic inflammation, have permitted to escape purulent complications occurrence while an acute aseptic accumulations of liquid are present in bursa omentalis in 96.1% of patients and in cellular tissue of retroperitoneal space--in 69.6%. | 21548323 |
| Inflammation, Fibrosis Assessment | Altered Intercellular Communication | We then focused on the impairment of hepatocyte proliferation, oxidative stress, and inflammation as potential mechanisms accelerating the development of fibrosis in the elderly. | 21548759 |
| ARCN1 gene, Inflammation | Altered Intercellular Communication | Changes in protein metabolism and systemic inflammation may contribute to increased resting energy expenditure (REE) in COPD, leading to an energy imbalance and loss of fat and fat-free mass. | 21550084 |
| ARCN1 gene, Inflammation | Altered Intercellular Communication | The objective of this study was to determine first whether REE was increased in patients with COPD and, second, whether this was associated with increased protein turnover and/or systemic inflammation. | 21550084 |
| Retinal Degeneration, Ischemia, Inflammation | Altered Intercellular Communication | PEVAC may develop in absence of capillary ischemia or inflammation, probably due to progressive retinal endothelial cell degeneration. | 21550688 |
| Necrotizing granulomatous inflammation | Altered Intercellular Communication | Biopsy revealed nonnecrotizing granulomatous inflammation with positive PTHrP staining by immunohistochemistry. | 21550945 |
| Inflammation, Specimen Type - Fistula, acute diverticulitis | Altered Intercellular Communication | Although most patients have experienced no prior episodes of acute diverticulitis, fistula formation is preceded by bouts of inflammation. | 21551188 |
| Virus Diseases, Myocarditis, Diabetes Mellitus | Altered Intercellular Communication | The mechanisms by which fulminant type 1 diabetes mellitus occurs is still uncertain, but the presence of islet injury accompanied by myocardial inflammation in the current case suggested that a viral infection accounted for the onset of this type of diabetes. | 21551959 |
| Inflammation, Kidney Diseases | Altered Intercellular Communication | Chronic inflammation plays a pivotal role in the development of renal disease. | 21552189 |
| Inflammation, Kidney Diseases | Altered Intercellular Communication | Awareness of other disturbed rhythms, such as inflammation processes, can affect the treatment of patients with renal disease. | 21552189 |
| Inflammation, Fibrosis Assessment, Tissue Adhesions | Altered Intercellular Communication | The most common reasons for conversion were severe adhesions caused by tissue inflammation (97 patients) and fibrosis of Calot's triangle (12 patients). | 21552665 |
| Inflammation, Prostate carcinoma | Altered Intercellular Communication | Chronic inflammation has been considered a potential risk factor for prostate cancer. | 21553150 |
| Neurodegenerative Disorders, physiopathological | Altered Intercellular Communication | The increased dopaminergic tone created in the OBs of these patients could reflect a compensatory mechanism created by the early degeneration of other neurotransmitter systems and might contribute to the olfactory dysfunction exhibited by patients with neurodegenerative disorders. | 21553300 |
| Inflammation, Prediabetes syndrome, diabetic | Altered Intercellular Communication | Considering the involvement of chronic inflammation in the pathophysiology of DM, the present study investigated an association between the ACACB gene polymorphism and high-sensitivity C-reactive protein (hsCRP) in a prediabetic and diabetic population. | 21553357 |
| Inflammation | Altered Intercellular Communication | The present data suggest that the ACACB gene C>T polymorphism may therefore be associated with chronic inflammation in this population. | 21553357 |
| Inflammation, Diabetes Mellitus, Non-Insulin-Dependent, Erectile dysfunction | Altered Intercellular Communication | Imbalanced low-grade inflammation and endothelial activation in patients with type 2 diabetes mellitus and erectile dysfunction. | 21554550 |
| Inflammation, Endothelial dysfunction, Coronary heart disease, Choline Dehydrogenase, Mitochondrial | Altered Intercellular Communication | Although a link among systemic inflammation, endothelial dysfunction, and ED is described in clinical situations mainly related with coronary heart disease (CHD) risk, evidences of this link in T2DM patients are rather limited. | 21554550 |
| Inflammation, Anger, Hostility | Altered Intercellular Communication | Trait anger, cynical hostility and inflammation in Latinas: variations by anger type? | 21554946 |
| Keratitis, Pseudomonas aeruginosa infection | Altered Intercellular Communication | TREM-1 amplifies corneal inflammation after Pseudomonas aeruginosa infection by modulating Toll-like receptor signaling and Th1/Th2-type immune responses. | 21555403 |
| Inflammation | Altered Intercellular Communication | While specific antiviral mechanisms remain to be elucidated, leflunomide shows unique bifunctional potential to both reduce viral load and, by virtue of its well-documented anti-inflammatory activity, attenuate the destructive inflammation associated with RSV disease. | 21555813 |
| Inflammation, Fibrosis Assessment, Asbestosis | Altered Intercellular Communication | The pathological features of asbestosis show the peribronchiolar fibrosis which suggest that asbestos fibers cause the inflammation of bronchioli. | 21556185 |
| Inflammation | Altered Intercellular Communication | Proliferative vitreoretinopathy (PVR), an eye-sight threatening complication of RRD surgery, resembles a wound-healing process with inflammation, scar tissue formation, and membrane contraction. | 21556354 |
| Gastroesophageal reflux disease, Collagen-vascular disease, Traumatic injury | Altered Intercellular Communication | Collagen-vascular disease, localized trauma, extraesophageal reflux (EER), and hormonal alterations have all been postulated as potential etiologies of iSGS. | 21557240 |
| Inflammatory Bowel Diseases, Gastrointestinal inflammation, Colitis | Altered Intercellular Communication | Fecal calprotectin (FC) is used as a marker for intestinal inflammation in inflammatory bowel disease (IBD) but there is no reliable marker for collagenous colitis (CC). | 21557718 |
| Airway structure, Asthma | Altered Intercellular Communication | Activated mast cell densities are increased on the airway smooth muscle in asthma where they may modulate muscle functions and thus contribute to airway inflammation, remodelling and airflow obstruction. | 21557752 |
| Inflammation, Fibrosis Assessment, Fatty degeneration | Altered Intercellular Communication | CBT significantly correlated with Brunt's fibrosis score (r = -0.49, P < 0.001) but not with steatosis (P = 0.23) or inflammation (P = 0.08). | 21557768 |
| Inflammation, Ischemic, Cerebrovascular accident | Altered Intercellular Communication | Does inflammation predispose to recurrent vascular events after recent transient ischaemic attack and minor stroke? | 21557802 |
| Inflammation, Ischemic | Altered Intercellular Communication | Inflammation is implicated in the pathogenesis and outcome of ischaemic injury. | 21557802 |
| Inflammation, Ischemic | Altered Intercellular Communication | Poststroke inflammation is associated with outcome but it remains unclear whether such inflammation precedes or results from ischaemic injury. | 21557802 |
| Cardiovascular Diseases | Altered Intercellular Communication | Interventions to reduce obesity-related inflammation may impact cardiovascular disease outcomes. | 21558084 |
| Viral myocarditis, Inflammation, Ventricular Dysfunction | Altered Intercellular Communication | In an animal model of viral myocarditis, plasma levels of thioredoxin and adiponectin have been reported to be associated with the severity of inflammation and recovery of ventricular dysfunction, respectively. | 21558477 |
| Inflammation, Acute myocardial infarction | Altered Intercellular Communication | Inflammation and polymorphonuclear neutrophils are shown to be important in the pathogenesis of acute myocardial infarction (AMI). | 21558855 |
| Multiple Organ Failure, Inflammation, Tissue injury, Colitis, Ischemic | Altered Intercellular Communication | The aim of the present study was to seek evidence for gut-derived signals in man in a group of eight patients undergoing elective abdominal aortic reconstruction, a procedure that is associated with sterile tissue injury, controlled colonic ischemia as a consequence of aortic cross-clamping, and a significant risk of developing systemic inflammation and multiple organ dysfunction syndrome. | 21558985 |
| Toxic effect | Altered Intercellular Communication | Investigation of systemic and mesenteric inflammatory signaling and gut-derived endothelial toxicity in patients undergoing high-risk abdominal aortic surgery. | 21558985 |
| Weight decreased, Diabetes Mellitus, Non-Insulin-Dependent | Altered Intercellular Communication | Our data suggest that the RYGB surgery, beyond weight loss, induces early beneficial hormonal changes which favor glycemic control in type 2 diabetes. | 21559794 |
| Inflammation, Ulcerative Colitis | Altered Intercellular Communication | Intracolonic infusion of fecal supernatants from ulcerative colitis patients triggers altered permeability and inflammation in mice: role of cathepsin G and protease-activated receptor-4. | 21560201 |
| Inflammation | Altered Intercellular Communication | However, the mechanisms through which Cat-G triggers inflammation are not fully elucidated. | 21560201 |
| Inflammation, Gastric metaplasia | Altered Intercellular Communication | Morphologically at 15% of the patients with gastric metaplasia was found moderate inflammation. | 21560383 |
| Chronic infectious disease, Inflammation, Esophagitis | Altered Intercellular Communication | Esophagitis in chronic viral infections was characterized by a higher frequency of erosive changes, higher activity of inflammation. | 21560383 |
| Inflammation | Altered Intercellular Communication | Prescribe a higher rate of airflow obstruction in older compared with patients younger than 60 years (from 65.5 and 39.8% respectively, p < 0.05), which increased with the duration of the disease Yak (in the elderly to a greater extent than in patients younger than 60 years), had no clear connection with the extent of inflammation in the intestine, while staying within 60-71.4% at any site of inflammation. | 21560623 |
| Inflammation, Primary malignant neoplasm, Cardiovascular Diseases, Diabetes Mellitus, nervous system disorder, Chronic disease, Lung diseases | Altered Intercellular Communication | Inflammation, although first characterized by Cornelius Celsus, a physician in first Century Rome, it was Rudolf Virchow, a German physician in nineteenth century who suggested a link between inflammation and cancer, cardiovascular diseases, diabetes, pulmonary diseases, neurological diseases and other chronic diseases. | 21561421 |
| Inflammation, Chronic disease | Altered Intercellular Communication | Extensive research within last three decades has confirmed these observations and identified the molecular basis for most chronic diseases and for the associated inflammation. | 21561421 |
| Inflammation, Chronic disease | Altered Intercellular Communication | Thus agents that can inhibit NF-kappaB and diminish chronic inflammation have potential to prevent or delay the onset of the chronic diseases and further even treat them. | 21561421 |
| Inflammatory abnormality of the eye, Choroiditis | Altered Intercellular Communication | Extradigestive manifestations can occur, especially ocular inflammation, but posterior choroidal inflammation is more unusual. | 21561686 |
| Inflammation, Restenosis | Altered Intercellular Communication | This study investigated whether markers of inflammation and the adipo-insular axis associated with T2DM and poor metabolic control were able to predict restenosis after PCI in T2DM patients. | 21562066 |
| Inflammation, Restenosis | Altered Intercellular Communication | Fasting glucose prior to the PCI was an independent predictor of restenosis in patients with T2DM while analyses of a variety of markers related to inflammation and the adipo-insular axis did not add any further information. | 21562066 |
| Malignant Neoplasms | Altered Intercellular Communication | Previously, chitinase 3-like 1 (CHI3L1) protein level was increased in various inflammatory conditions and cancers. | 21562723 |
| Inflammation, Prostate carcinoma | Altered Intercellular Communication | Common genetic variants in the Toll-like receptor 4 (TLR4), which is involved in inflammation and immune response pathways, may be important for prostate cancer. | 21563195 |
| Inflammation, Edema | Altered Intercellular Communication | However, changes in WC due to inflammation and edema may also affect the MTR. | 21563257 |
| Inflammation, Edema | Altered Intercellular Communication | MTR was correlated with WC in MS tissue, indicating that inflammation and edema influence MTR. | 21563257 |
| Inflammation, Mucosal Infection | Altered Intercellular Communication | In most cases the inflammation is connected with nasal mucosa infection. | 21563449 |
| Periapical bone loss | Altered Intercellular Communication | It is most often connected with periapical lesions, complications following dental procedures and oroantral fistula inflammation. | 21563449 |
| Communicable Diseases, Inflammation | Altered Intercellular Communication | Endpoints assessed were tube exposure, graft thinning, graft clarity, graft-related infection, and inflammation. | 21563743 |
| Hepatic inflammation, Hyperferritinaemia | Altered Intercellular Communication | Persistent hyperferritinaemia seems to be a risk biomarker of GMA in patients with PCT, probably in the setting of chronic iron overload and hepatic inflammation. | 21564073 |
| Inflammation, Inflammatory dermatosis, Pustulosis of Palms and Soles | Altered Intercellular Communication | The acrosyringium is the target for inflammation in the chronic and intensely inflammatory skin disease palmoplantar pustulosis (PPP). | 21564193 |
| ARCN1 gene, Chronic Obstructive Airway Disease, Airway Obstruction, Airway structure | Altered Intercellular Communication | Chronic obstructive pulmonary disease (COPD) is characterized by irreversible airway obstruction and persistent chronic airway inflammation and is influenced by genetic and environmental factors. | 21565178 |
| Inflammation, Atherosclerosis | Altered Intercellular Communication | Inflammation and immune response play an important role in the pathogenesis of atherosclerosis. | 21565239 |
| Inflammatory Bowel Diseases, Inflammation, Colorectal Carcinoma, Neoplasms | Altered Intercellular Communication | Inflammatory bowel disease (IBD) increases the risk of colorectal cancer (CRC), indicating that inflammation might alter tumor characteristics and potentially affect treatment and survival. | 21565283 |
| Inflammation, Coronary Artery Disease | Altered Intercellular Communication | Epicardial adipose tissue has been linked to cardiovascular metabolism and inflammation and has been shown to predict prevalence and progression of coronary artery disease. | 21565323 |
| Inflammation, Fibrosis Assessment, Tubular atrophy, Allograft surgical material | Altered Intercellular Communication | Inflammation, interstitial fibrosis (IF), and tubular atrophy (TA) precede chronic transplant dysfunction, which is a major cause of renal allograft loss. | 21566051 |
| Inflammation | Altered Intercellular Communication | Here, we studied PTC number, IF/TA, inflammation, and renal function in 48 patients who underwent protocol biopsies. | 21566051 |
| Inflammation | Altered Intercellular Communication | Fewer PTCs in the 3-month biopsy correlated with high IF/TA and inflammation scores and predicted lower renal function at 1 year. | 21566051 |
| Necrotizing granulomatous inflammation, Schistosoma | Altered Intercellular Communication | Biopsy of the mass showed transmural granulomatous inflammation interpreted as schistosomal granuloma, ruling out lymphoma. | 21566088 |
| Cessation of life, Inflammation | Altered Intercellular Communication | Cell death, inflammation and loss of proteoglycans participate in these mechanisms with p38MAPK being one of the pivotal signaling kinases. | 21567074 |
| Inflammation, Gastritis | Altered Intercellular Communication | These data in humans with and without gastritis are consistent with the hypothesis that local factors influence ectopic gastric IF expression, arising from either the anatomical location, the focal inflammation, or both. | 21567190 |
| Inflammation | Altered Intercellular Communication | Additionally, this case reinforces the hypothesis that local inflammation has a pathogenic role. | 21567376 |
| Inflammation, Ototoxicity, Ischemic stroke | Altered Intercellular Communication | These findings suggest that neuroprotective properties of neuroserpin may be related to the inhibition of excitotoxicity, inflammation, as well as blood brain barrier disruption that occur after acute ischemic stroke. | 21569344 |
| Inflammation | Altered Intercellular Communication | The prevalence of C. tropicalis significantly increased with the highest degree of inflammation (P < .05). | 21569989 |
| Inflammation, Spinal Cord Injuries | Altered Intercellular Communication | Systemic inflammation and reduced pulmonary function in chronic spinal cord injury. | 21570031 |
| Inflammation, Spinal Cord Injuries, Stanford Cancer Institute | Altered Intercellular Communication | To evaluate the relationship between systemic inflammation and pulmonary function in persons with chronic spinal cord injury (SCI). | 21570031 |
| Inflammation, Stanford Cancer Institute, Neuromuscular | Altered Intercellular Communication | These results suggest that the reduction of pulmonary function after SCI is related not only to neuromuscular impairment but also to factors that promote systemic inflammation. | 21570031 |
| Inflammation | Altered Intercellular Communication | High mobility group chromosomal protein B1 (HMGB1) and N2 (HMGN2), two members of high mobility group (HMG) family, play important role in inflammation. | 21570059 |
| Inflammation, Thrombosis | Altered Intercellular Communication | Endothelial function represents a crucial factor for the regulation of vascular tonus and its malfunction influences the formation of thrombosis and inflammation. | 21570519 |
| Cardiovascular morbidity, Inflammation, Peripheral Arterial Diseases | Altered Intercellular Communication | Subjects with peripheral artery disease (PAD) are at increased risk of cardiovascular morbidity and mortality, perhaps in part, related to increased levels of inflammation, platelet activity, and lipids. | 21570531 |
| Hepatic inflammation, hepcidin, Fatty Liver Disease | Altered Intercellular Communication | No associations between hepatic inflammation/iron content on liver biopsy and variables of lipid metabolism were found but hepcidin correlated with hepatic inflammation in all patients and with NAS scores in NASH. | 21570653 |
| Inflammation, Fatty Liver Disease | Altered Intercellular Communication | The correlation of H with sd-LDL and IRI, without relation to hepatic iron content suggests a putative link between inflammation, carbohydrate and lipid metabolism in NASH. | 21570653 |
| Inflammation, Small bowel bacterial overgrowth syndrome, Immunocompromised Host, Restless Legs Syndrome, hepcidin | Altered Intercellular Communication | Three hypotheses developed are (a) RLS patients are selectively immunocompromised or genetically predisposed and thus more subject to SIBO; (b) SIBO leads to autoimmune changes, and subsequent auto-antibodies attack brain and/or peripheral nerves and (c) SIBO inflammation leads to increased hepcidin and CNS iron deficiency which, in turn, leads to RLS. | 21570907 |
| Inflammation, Obesity | Altered Intercellular Communication | They are increasingly determined by low-grade inflammation, independently of central obesity. | 21571245 |
| Degenerative polyarthritis, Inflammation | Altered Intercellular Communication | No association between markers of inflammation and osteoarthritis of the hands and knees. | 21572158 |
| Degenerative polyarthritis, Inflammation | Altered Intercellular Communication | Local inflammation plays a prominent role in osteoarthritis (OA). | 21572158 |
| Inflammation, Viremia | Altered Intercellular Communication | Regardless of aggressive screening, peak viremia and inflammation occurred before enrollment and potential intervention. | 21573003 |
| Inflammation, Necrosis, Autoimmune Diseases, Pulmonary Emphysema, Chronic Obstructive Airway Disease | Altered Intercellular Communication | These data suggest that higher expression of CD46 in the lungs of ex-smoker protects them from emphysema and chronic obstructive pulmonary disease by clearing the inflammation impeding the proliferation of CD8(+) T cells and necrosis, achieved by production of T regulatory cells and degradation of C3b; restraining the complement cascade favors apoptosis over necrosis, protecting them from autoimmunity and chronic inflammation. | 21573156 |
| Gastric mucosa, Carcinogenesis, Gastritis | Altered Intercellular Communication | This study was executed to prove the existence of c-Kit-positive interstitial cells of Cajal (ICC)-like cells [c-Kit (+) ICC-like cells] and their possible role associated with gastric inflammation and/or carcinogenesis in human gastric mucosa. | 21573494 |
| Infection, EBV-Related Sarcoma | Altered Intercellular Communication | Intrathecal EBV activity is not restricted to typical EBV-related disorders, unexpectedly frequent in further CNS infections and also present in non-inflammatory conditions. | 21573818 |
| Inflammation, Carcinogenesis, Neoplasms | Altered Intercellular Communication | Apoptosis and induction of inflammation by tumor released cytokines as tumor escape mechanisms have been proposed to play an important role in colorectal carcinogenesis. | 21573932 |
| Neoplasms | Altered Intercellular Communication | TNF-a expression by tumor cells may be an efficient immunological escape mechanism by inflammation-enhanced metastases and probably by induction of apoptosis in tumor-infiltrating CD8+ immune cells resulting in a down regulation of the tumoral immune response. | 21573932 |
| Hypophysitis, CTCAE, Inflammation, Disease, Pituitary Function Tests | Altered Intercellular Communication | Hypophysitis is an inflammation of the pituitary gland and includes a heterogeneous group of diseases presenting with impaired pituitary gland function. | 21574123 |
| Communicable Diseases, Inflammation, Necrosis, Granulomatous inflammation | Altered Intercellular Communication | Granulomatous inflammation with fibrinoid necrosis was present in 47% of lesions in patients with M. marinum infection and suppurative granulomatous inflammation was noted in 45% of patients with RGM infection. | 21575304 |
| Inflammation | Altered Intercellular Communication | Xanthogranulomatous inflammation of ascending colon with mucosal involvement: report of a first case. | 21575889 |
| Inflammation | Altered Intercellular Communication | Xanthogranulomatous inflammation (XGI) is a rare phenomenon and can involve any organ system. | 21575889 |
| Inflammation | Altered Intercellular Communication | CSF inflammation persisted and a gradual increase in granulation tissue was found in the subdural space on lumbar MRI. | 21576840 |
| Gingivitis | Altered Intercellular Communication | Clinical examination revealed marked gingival inflammation, moderate gingival recession and mobility of some of his lower anterior teeth: 31, 32, and 33. | 21577000 |
| Inflammation, Arteritis | Altered Intercellular Communication | Quantification of supra-aortic arterial wall inflammation in patients with arteritis using high resolution dynamic contrast-enhanced magnetic resonance imaging: initial results in correlation to [18F]-FDG PET/CT. | 21577125 |
| Inflammation, Arteritis | Altered Intercellular Communication | : DCE-MRI is able to measure arterial inflammation reliably and noninvasively with good correlation to [F]-FDG PET/CT in patients suffering from arteritis of the supraaortic arteries. | 21577125 |
| Fibrosis Assessment, Pancreatitis, Chronic | Altered Intercellular Communication | Recently, two studies on rats reported that tobacco smoking is associated with chronic pancreatic inflammation with fibrosis and scarring of pancreatic acinar structures. | 21577244 |
| Intestinal metaplasia, Gastritis, Infection caused by Helicobacter pylori | Altered Intercellular Communication | Increased gastric osteopontin expression by Helicobacter pylori Infection can correlate with more severe gastric inflammation and intestinal metaplasia. | 21585607 |
| Intestinal metaplasia | Altered Intercellular Communication | The study validated whether OPN expressions correlate with Helicobacter pylori-related chronic gastric inflammation and the precancerous change as intestinal metaplasia (IM). | 21585607 |
| Gastritis | Altered Intercellular Communication | For the H. pylori-infected subjects, the gastric inflammation was assessed by the Updated Sydney System. | 21585607 |
| Gastritis, Infection caused by Helicobacter pylori | Altered Intercellular Communication | For the H. pylori-infected patients, an increased OPN expression correlated with more severe chronic gastric inflammation (p < .001) and the presence of IM (OR: 2.6, 95% CI: 1.15-5.94, p = .02). | 21585607 |
| Gastritis, Infection caused by Helicobacter pylori | Altered Intercellular Communication | Increased gastric OPN expression by H. pylori infection can correlate with a more severe gastric inflammation and the presence of IM. | 21585607 |
| Inflammation, Negative Regulation of Cell Cycle | Altered Intercellular Communication | For this purpose, markers for inflammation (COX-2, CD3, CD8), apoptosis (p53), cell cycle arrest (p53, p21), proliferation (Ki67), and angiogenesis (CD31) were examined. | 21585654 |
| Inflammation, Fibrous | Altered Intercellular Communication | No loose BONIT-HA particles or delamination of the coating were observed, and there was no inflammation or fibrous interposition at the interface. | 21586774 |
| Infertility, Neoplasms | Altered Intercellular Communication | Organ-sparing surgery for the contralateral testicular tumor following orchiectomy, can be considered to avoid infertility and hormonal substitutions. | 21586887 |
| Inflammation, Rupture | Altered Intercellular Communication | The mass had gradually enlarged for a 25-year period without inflammation or rupture. | 21586972 |
| Inflammation, Observation Method - Coagulation | Altered Intercellular Communication | Plasma markers of inflammation, coagulation and angiogenesis were measured. | 21587257 |
| Inflammation, Acute onset pain | Altered Intercellular Communication | Interestingly, AKT2 mRNA was up-regulated in patients with acute pain during the first 12 months, indicating that AKT2 transcriptional activation may be associated with acute rather than chronic inflammation and phagocytosis. | 21590431 |
| Inflammation | Altered Intercellular Communication | The authors propose the choice of applied surgical technique by taking into account difficulties consequential to the anatomy of this region, as well as additional complications regarding the chronic inflammation process. | 21591367 |
| Granulomatous inflammation | Altered Intercellular Communication | Her serum PR3-ANCA titer was high, and granulomatous inflammation with Langhans giant cell was noted in a transbronchial biopsy specimen. | 21591462 |
| Sample Size Calculation, Inflammation, Left ventricular diastolic dysfunction, Lupus Erythematosus, Systemic | Altered Intercellular Communication | Overproduction of collagen in SSc results in diastolic left ventricular dysfunction, while generalized inflammation in SLE and DPM leads mainly to pathologic changes on valvular leaflets and/or pericardium. | 21591573 |
| Acute Coronary Syndrome, vascular inflammations | Altered Intercellular Communication | Studies have identified that MRP8/14 regulates vascular inflammation and serves as a novel marker of acute coronary syndrome. | 21592353 |
| Diastolic dysfunction, Inflammation | Altered Intercellular Communication | The association between inflammation and left ventricular (LV) diastolic dysfunction in continuous ambulatory peritoneal dialysis (CAPD) and non-CAPD patients is not established. | 21592755 |
| Diastolic dysfunction, Inflammation | Altered Intercellular Communication | The objective of this study was to test the above association and whether inflammation interacts with CAPD to increase LV diastolic dysfunction risks. | 21592755 |
| Diastolic dysfunction, Inflammation, Left ventricular diastolic dysfunction | Altered Intercellular Communication | In a multivariate regression analysis adjusting for all the factors associated with LV diastolic dysfunction, inflammation is still significantly associated with left ventricular diastolic dysfunction (TNF-alpha, OR: 2.6, 95% CI: 2.0-3.35, p < 0.001; IL-6, OR: 1.26, 95% CI: 1.25-1.26, p = 0.01). | 21592755 |
| Diastolic dysfunction, Inflammation | Altered Intercellular Communication | In addition, the interaction of CAPD and inflammation significantly contributed to the development of LV diastolic dysfunction (CAPD* TNF-a: OR: 1.45, 95% CI: 1.13-1.79, P = 0.004). | 21592755 |
| Diastolic dysfunction, Inflammation | Altered Intercellular Communication | We found inflammation plays a vital role for LV diastolic dysfunction especially in CAPD patients. | 21592755 |
| Diastolic dysfunction, Inflammation | Altered Intercellular Communication | A synergistic effect between CAPD and inflammation, especially TNF-a, would further aggravate LV diastolic dysfunction. | 21592755 |
| Rheumatoid Arthritis, Inflammation, Inflamed joint | Altered Intercellular Communication | IL-27-producing CD14(+) cells infiltrate inflamed joints of rheumatoid arthritis and regulate inflammation and chemotactic migration. | 21592822 |
| Hepatitis, Liver Cirrhosis | Altered Intercellular Communication | The IL28B rs12979860 CC genotype is associated with a higher prevalence of cirrhosis in HIV-HCV-coinfected patients than CT/TT genotypes, suggesting that IL28B CC carriers may experience a more rapid progression of HCV-related liver fibrosis, perhaps as result of increased liver inflammation. | 21592993 |
| Hypophysitis, CTCAE, Inflammation | Altered Intercellular Communication | Hypophysitis is a chronic inflammation of the pituitary gland that comprises an increasingly complex clinicopathological spectrum. | 21593109 |
| Inflammation, Diabetes Mellitus | Altered Intercellular Communication | Klotho depletion contributes to increased inflammation in kidney of the db/db mouse model of diabetes via RelA (serine)536 phosphorylation. | 21593200 |
| Inflammation, Kidney | Altered Intercellular Communication | We investigated whether Klotho levels and signaling modulate inflammation in diabetic kidneys. | 21593200 |
| Inflammation | Altered Intercellular Communication | There was no evidence of multicellular micrometastases sufficiently large to require angiogenesis and no associated inflammation was observed. | 21593344 |
| Meckel Diverticulum, Congenital Abnormality, Gastrointestinal Hemorrhage, Intestinal Obstruction, Acute inflammation | Altered Intercellular Communication | Meckel diverticulum is the most common congenital anomaly of the small intestine that generally comes to attention due to a variety of complications, such as gastrointestinal tract bleeding, bowel obstruction or acute inflammation. | 21594546 |
| Inflammation, Atrophic | Altered Intercellular Communication | Furthermore, the levels of histological parameters of activity, inflammation, and atrophy in the gastric corpus, but not in the gastric antrum, were significantly more severe in responders than in nonresponders,. | 21594563 |
| Idiopathic hypertrophic pachymeningitis, Bone Marrow Diseases, Proliferative inflammation, Pain Distress Question | Altered Intercellular Communication | Idiopathic hypertrophic spinal pachymeningitis (IHSP) is a comparatively rare disease characterized by hypertrophic inflammation of the dura mater and clinical symptoms that progress from local pain to myelopathy. | 21594749 |
| Inflammation, Lower Urinary Tract Symptoms | Altered Intercellular Communication | It can be inferred that inflammation may be involved in the processes of LUTS. | 21594882 |
| Inflammation, Elastoid degeneration | Altered Intercellular Communication | Inflammation was more pronounced in blurred OCT images, whereas solar elastosis dominated in easily identified lesions. | 21595042 |
| Renal Insufficiency, Inflammation, Malignant Neoplasms, Liver Dysfunction | Altered Intercellular Communication | Plasma YB-1/p18 can identify patients with malignancies, independent of acute inflammation, renal impairment or liver dysfunction. | 21595987 |
| Inflammation, Hypoadiponectinemia, Aortic Valve Stenosis | Altered Intercellular Communication | Hypoadiponectinemia is associated with valvular inflammation and faster disease progression in patients with aortic stenosis. | 21597293 |
| Aneurysm, Inflammation | Altered Intercellular Communication | This aneurysm was firm and thick and adhered to some organs due to inflammation. | 21597420 |
| Inflammation, Bacterial Infections, Acute otitis media | Altered Intercellular Communication | Acute otitis externa (AOE) (swimmer's ear) is inflammation of the external auditory canal most often caused by bacterial infection. | 21597452 |
| Kidney Failure, Chronic, Inflammation | Altered Intercellular Communication | We tested whether 25(OH)D concentration is associated with markers of vascular remodeling and inflammation in African American ESRD patients. | 21600051 |
| Inflammation, Depression, CTCAE, atherosclerotic | Altered Intercellular Communication | Depression and inflammation have been suggested to be involved in the atherosclerotic processes, but empirical evidence is mixed. | 21600662 |
| Inflammation, Bipolar Disorder, Atherosclerosis | Altered Intercellular Communication | We tested the hypothesis that depressive symptoms are associated with atherosclerosis only when combined with other risk factors, such as inflammation indicated by indoleamine 2,3-dioxygenase (IDO) activation. | 21600662 |
| Carotid Atherosclerosis, Inflammation, Bipolar Disorder | Altered Intercellular Communication | These data suggest that depressive symptoms are associated with preclinical y carotid atherosclerosis only if they are linked to inflammation, and that this association is present only in women. | 21600662 |
| Inflammation, Helicobacter pylori | Altered Intercellular Communication | Helicobacter pylori (H. pylori) is a Gram-negative bacterium that is well known in the involvement of chronic inflammation in the gastric mucosa of the human stomach. | 21604199 |
| Inflammation, Depression, CTCAE, Suicide | Altered Intercellular Communication | Inflammation has been linked to depression and suicide risk. | 21605657 |
| Inflammation | Altered Intercellular Communication | Chronic inflammation was found to play an important role in the development of cardiovascular risk factors. | 21605731 |
| Lichen Planus, Inflammation, Dyslipidemias | Altered Intercellular Communication | Chronic inflammation in patients with lichen planus may explain the association with dyslipidemia. | 21605731 |
| Inflammation, Dental Plaque | Altered Intercellular Communication | Inflammation plays a crucial role in plaque vulnerability. | 21605863 |
| Arterial Stiffness, Inflammation | Altered Intercellular Communication | In healthy subjects without confounding risk factors or significant systemic inflammation, a high cystine level, reflecting extracellular oxidant burden, is associated with increased arterial stiffness and wave reflections. | 21605864 |
| Neuronal degeneration, "Alzheimers Disease", Data types - Address | Altered Intercellular Communication | Alzheimer's disease (AD) is a neurodegenerative process characterized by progressive neuronal degeneration, reduced levels of neurotransmitters, and altered forms of synaptic plasticity. | 21606570 |
| Inflammation | Altered Intercellular Communication | Both disease activity and cumulative damage scores did not change after the intervention, and no evidence of exercise-induced exacerbation of inflammation was observed. | 21606873 |
| Inflammation, "Alzheimers Disease | Altered Intercellular Communication | Dietary inflammation factor rating system and risk of Alzheimer disease in elders. | 21606905 |
| Inflammation, "Alzheimers Disease", Data types - Address | Altered Intercellular Communication | It has been suggested that inflammation is involved in Alzheimer disease (AD) pathogenesis. | 21606905 |
| Inflammation, Data types - Address | Altered Intercellular Communication | In addition, although it remains possible that tIFR might be related with some other aspects of inflammation not captured by hsCRP, lack of association with AD risk suggests its limited clinical utility. | 21606905 |
| Degenerative polyarthritis, Inflammatory disorder | Altered Intercellular Communication | This study suggests that short-term (2 weeks) calcium fructoborate supplementation in patients with osteoarthritis symptoms has a favorable prognosis on inflammation diseases. | 21607703 |
| Refractory Cytopenia of Childhood, Inflammation | Altered Intercellular Communication | Our data allow us to conclude that the control of tumor-associated inflammation is an important therapeutic principle in patients with metastatic RCC. | 21607771 |
| Inflammation | Altered Intercellular Communication | This leads to the idea that ageing is a result of a chronic inflammation process and to the term "inflammageing". | 21607797 |
| Inflammation | Altered Intercellular Communication | This leads to the idea that ageing is a result of a chronic inflammation process and to the term "inflammageing". | 21607797 |
| Arthritis | Altered Intercellular Communication | Additionally, approximately 30% of the synovial FOXP3(+) T cells were Ki67(+) and hence actively dividing, but proliferation did not overlap with cytokine production, suggesting that these cells represent functional Tregs having met their cognate antigen and expanded in an attempt to alleviate joint inflammation. | 21607944 |
| Inflammation, Edema | Altered Intercellular Communication | He had occasional mild edema of the right leg, but no signs of inflammation or recurrence of the angiomyomas. | 21609161 |
| Inflammation, Fibrosis Assessment, Congestive heart failure | Altered Intercellular Communication | The authors found significant increases in myocyte size, myocardial fibrosis, and inflammation in both CHF groups who underwent CRT or LVAD, compared with healthy controls. | 21609388 |
| Inflammation, Hypomagnesemia, Metabolic Syndrome X | Altered Intercellular Communication | Severe hypomagnesemia and low-grade inflammation in metabolic syndrome. | 21609903 |
| Inflammation, Primary malignant neoplasm, Intrahepatic bile duct | Altered Intercellular Communication | An increased intrahepatic bile duct pressure following cholecystectomy might cause chronic inflammation in the surrounding liver tissue, which might induce cancer development. | 21610710 |
| Inflammation, Stomach ache, Anorexia | Altered Intercellular Communication | These were stomach ache, loss of appetite, lethargy and inflammation of the face and body. | 21610855 |
| Inflammation, physiopathological | Altered Intercellular Communication | Based on these findings we argue that GATA3 serves as a key regulator in psoriatic inflammation, keratinocyte hyperproliferation and skin barrier dysfunction. | 21611195 |
| Inflammation | Altered Intercellular Communication | Consistent with previous observations, a barrier defect and frequent infiltration of neutrophils was observed, suggesting that focal p120 loss generates a microenvironment disposed to chronic inflammation. | 21611205 |
| Inflammation | Altered Intercellular Communication | Given that byproducts of inflammation are known to be highly mutagenic, we suggest that tumorigenesis in this model is ultimately driven by the lifelong inability to heal chronic wounds and the substantially increased rates of stochastic gene mutation in tissue microenvironments subjected to chronic inflammation. | 21611205 |
| Interstitial inflammation | Altered Intercellular Communication | Kidney biopsy revealed expanded mesangium, thickened capillary loops and epimembranous spikes, with no significant interstitial inflammation or thickened tubular basement membranes. | 21612326 |
| Inflammation, Chronic Kidney Diseases | Altered Intercellular Communication | Low-fructose diet lowers blood pressure and inflammation in patients with chronic kidney disease. | 21613382 |
| Inflammation, Hypertension, CTCAE, Hyperuricemia | Altered Intercellular Communication | Fructose has been strongly linked with hypertension, hyperuricemia and inflammation in experimental models and humans. | 21613382 |
| Inflammation, Hyperuricemia, Kidney Diseases, Chronic Kidney Diseases | Altered Intercellular Communication | However, the effect of low-fructose diet on inflammation, hyperuricemia and the progression of renal disease has not yet been evaluated in patients with chronic kidney disease (CKD). | 21613382 |
| Inflammation, Chronic Kidney Diseases | Altered Intercellular Communication | Low-fructose diet in subjects with CKD can reduce inflammation with some potential benefits on BP. | 21613382 |
| Inflammation, Metabolic Syndrome X | Altered Intercellular Communication | Moreover, associations between serum 25(OH)D and metabolic syndrome (MetSyn), insulin resistance (IR), and inflammation are unclear in children. | 21613551 |
| Inflammation, Fibrosis Assessment, Calcinosis | Altered Intercellular Communication | Thus, fetuin-A levels are influenced by chronic inflammation and actively affect fibrosis and calcification processes, respectively. | 21613794 |
| Inflammation, Fibrosis Assessment, Calcinosis, Tubular atrophy, Renal Allograft Thrombosis | Altered Intercellular Communication | Graft rejection, interstitial fibrosis and tubular atrophy, chronic inflammation and calcification are common causes for kidney allograft loss. | 21613794 |
| Carcinomatosis, Inflammation, Fibrosis Assessment, borderline ovarian tumor | Altered Intercellular Communication | Diffuse intraabdominal fibrosis and inflammation mimicking peritoneal carcinomatosis recurred after surgery for borderline ovarian tumor misdiagnosed by 18F-fluorodeoxyglucose-positron emission tomography. | 21614927 |
| Inflammation, Fibrosis Assessment, borderline ovarian tumor | Altered Intercellular Communication | Based on imaging and intraoperative findings, multiple intraabdominal masses strongly suggested peritoneal recurrence from a previous ovarian borderline tumor, but it finally proved to be inflammation and fibrosis on histopathologic examination. | 21614927 |
| Inflammation | Altered Intercellular Communication | Therefore, the possibility of a false-positive diagnosis due to benign conditions, such as inflammation, should always be taken into consideration. | 21614927 |
| Colonic Diseases, Functional, Paraganglioma | Altered Intercellular Communication | Postoperatively, patients with paragangliomas should receive hormonal evaluation for functional disease, imaging evaluation for multicentric and metastatic disease, and genetic counseling. | 21615305 |
| Inflammation, SLC22A5 gene | Altered Intercellular Communication | Chronic inflammation also plays an important role in the pathophysiology of SCD. | 21615396 |
| Inflammation, Greeks, SLC22A5 gene | Altered Intercellular Communication | We aimed to investigate endothelial activation in Caucasian Greek patients with SCD by means of measuring adhesion molecules and markers of inflammation. | 21615396 |
| Inflammation | Altered Intercellular Communication | Our findings demonstrate the high degree of endothelial activation and damage seen in sickle cell patients even in steady-state condition, as well as the important chronic inflammation underlying the pathophysiology of this widespread disease. | 21615396 |
| Pneumonitis | Altered Intercellular Communication | Aged mice had increased lung inflammation as determined by cytokine analysis and histopathology of lung sections. | 21615674 |
| Inflammation, Pneumonia | Altered Intercellular Communication | Genotoxic stress induced by bleomycin and oxidative stress enhanced susceptibility of young mice to pneumonia and was positively correlated with enhanced p16, inflammation, and LR levels. | 21615674 |
| Hermanski-Pudlak Syndrome, Pneumonitis | Altered Intercellular Communication | Early alveolar epithelial dysfunction promotes lung inflammation in a mouse model of Hermansky-Pudlak syndrome. | 21616998 |
| Inflammation, Hermanski-Pudlak Syndrome, Hantavirus Infections | Altered Intercellular Communication | The pulmonary phenotype of Hermansky-Pudlak syndrome (HPS) in adults includes foamy alveolar type 2 cells, inflammation, and lung remodeling, but there is no information about ontogeny or early disease mediators. | 21616998 |
| Fibrosis Assessment, Pneumonitis | Altered Intercellular Communication | EPPE mice develop increased total lung phospholipid, followed by a macrophage-predominant pulmonary inflammation, and lung remodeling including fibrosis. | 21616998 |
| Inflammation, Pneumonitis, Hantavirus Infections | Altered Intercellular Communication | Inflammation is initiated from the abnormal alveolar epithelial cells in HPS, and S-nitrosylated SP-D plays a significant role in amplifying pulmonary inflammation. | 21616998 |
| Inflammation | Altered Intercellular Communication | However, there were no positive inflammation signals and no clear elevated rheuma-immunology. | 21617278 |
| Airway structure | Altered Intercellular Communication | FeNO, as a marker of airway inflammation, ACT score, and the results of spirometry have been evaluated after switching to maintenance therapy by FBC 640/18 mg/day for 8 weeks. | 21617360 |
| Inflammation, Liver carcinoma | Altered Intercellular Communication | Analysis of factors affecting recurrence of hepatocellular carcinoma after liver transplantation with a special focus on inflammation markers. | 21617590 |
| Inflammation, Liver neoplasms | Altered Intercellular Communication | Systemic inflammation markers, such as neutrophil-to-lymphocyte ratio (NLR), have recently emerged as the prognostic factors for recurrence of liver tumors. | 21617590 |
| Intraocular inflammation | Altered Intercellular Communication | We recently demonstrated that aA-crystallin, a molecular chaperone, protected photoreceptors from apoptotic signals in intraocular inflammation. | 21617844 |
| White matter, Lupus Erythematosus | Altered Intercellular Communication | Neuroimaging evidence of white matter inflammation in newly diagnosed systemic lupus erythematosus. | 21618460 |
| Inflammation, Lupus Erythematosus, Systemic | Altered Intercellular Communication | The primary pathophysiology of CNS involvement in SLE is thought to be inflammation secondary to autoantibody-mediated vasculitis. | 21618460 |
| Inflammation, Atrophic, Hypometabolism | Altered Intercellular Communication | Neuroimaging studies have shown hypometabolism (representing impending cell failure) and atrophy (representing late-stage pathology), but not inflammation. | 21618460 |
| Inflammation, Hypermetabolism, Atrophic, Hypometabolism | Altered Intercellular Communication | The purpose of this study was to detect the presence and regional distribution of inflammation (hypermetabolism) and tissue failure, apoptosis, or atrophy (hypometabolism). | 21618460 |
| Inflammation, Hypermetabolism, Inflammatory disorder | Altered Intercellular Communication | The SELENA-SLEDAI-correlated increases in glucose consumption are potential evidence of inflammation, consistent with prior reports of hypermetabolism in inflammatory disorders. | 21618460 |
| Inflammation, Lupus Erythematosus, Systemic | Altered Intercellular Communication | To our knowledge, this is the first imaging-based evidence of SLE-induced CNS inflammation in an SLE inception cohort. | 21618460 |
| Inflammation, Ulcerative Colitis, Colitis | Altered Intercellular Communication | In ulcerative colitis (UC) patients, the median Simple Clinical Colitis Activity Index (SCCAI) was 4 (range 0-10) in mild and 6 (range 0-14) in patients with moderate or severe endoscopic activity of inflammation (p = 0.002). | 21619483 |
| Crohn Disease, Inflammatory disease of mucous membrane | Altered Intercellular Communication | In Crohn's disease (CD) patients, there was no statistical significant association between the Harvey-Bradshaw Index (HBI) and the endoscopic grade of mucosal inflammation (p = 0.8). | 21619483 |
| Inflammation, vinyltriethoxysilane | Altered Intercellular Communication | Thus far, a causal relationship between inflammation and VTE remains to be clarified and more prospective data are warranted. | 21620438 |
| Inflammation, Ovarian Serous Adenocarcinoma, Malignant Neoplasms | Altered Intercellular Communication | Two cases with suspicion for malignancy underwent conversion to laparotomy (2.1%), and frozen sections revealed serous ovarian adenocarcinoma (n=1) and chronic inflammation (n=1). | 21620559 |
| Malignant neoplasm of skin, Inflammation | Altered Intercellular Communication | Environmental and endogenous stresses to skin are considered causative reasons for skin cancers, premature ageing, and chronic inflammation. | 21620684 |
| Encephalitis, Vasculitis, CTCAE | Altered Intercellular Communication | Pathological evidence of both vasculitis and encephalitis has never been previously reported in any inflammatory condition affecting the brain. | 21620774 |
| Inflammation, Atherosclerotic lesion | Altered Intercellular Communication | Cholesterol crystals have been shown to cause inflammation, and ultimately atherosclerotic lesions through the activation of the NLRP3 inflammasome. | 21621776 |
| Infarction, Inflammation | Altered Intercellular Communication | Restricted diffusion in the optic nerve detected with MRI has been previously reported in infarction and inflammation but not in infiltrative neoplasm. | 21623229 |
| Inflammation, Neoplasms | Altered Intercellular Communication | Acute inflammation markers and tumor stimulating factors may not reflect clinical benefits of laparoscopic surgery. | 21623607 |
| Inflammation, Irritation | Altered Intercellular Communication | Because inflammation is a factor promoting ageing, all-trans retinoic acid (RA)-induced irritation may have a negative influence on collagen accumulation in human skin despite its stimulation of collagen production. | 21623752 |
| Refractory anemias, Inflammation | Altered Intercellular Communication | Excessive RA-induced inflammation might prevent collagen accumulation in aged skin despite the positive effect of RA on collagen production. | 21623752 |
| Inflammation, Pathologic Neovascularization, Calcinosis | Altered Intercellular Communication | Neovascularity and calcification were seen in 1 lesion and mild to moderate inflammation was seen in 3 lesions. | 21624622 |
| Inflammation | Altered Intercellular Communication | Neutrophil gelatinase-associated lipocalin (NGAL) is released by renal tubular cells in response to inflammation and injury. | 21624735 |
| Inflammation | Altered Intercellular Communication | These results suggest that uric acid contributes to systemic inflammation in humans and are in line with experimental data showing that uric acid triggers sterile inflammation. | 21625475 |
| Inflammation | Altered Intercellular Communication | CD163, a haptoglobin-hemoglobin (Hp-Hb) scavenger receptor, expressed by monocytes and macrophages, is important in resolution of inflammation. | 21625498 |
| HIV Antigens | Altered Intercellular Communication | Our findings clarify technical issues regarding CD163 expression on monocyte subsets and further elucidates its role in HIV-associated inflammation by demonstrating that CD163 is readily lost from CD14++CD16- monocytes and induced in pro-inflammatory CD14+CD16++ monocytes by M-CSF. | 21625498 |
| Renal Insufficiency, Inflammation, Spinal Fractures | Altered Intercellular Communication | Postmenopausal White women with mild renal dysfunction were at increased risk of nonvertebral fracture; this association was at least partially explained by effects of renal dysfunction on chronic inflammation. | 21625880 |
| Inflammation | Altered Intercellular Communication | A left orbital biopsy showed xanthogranulomatous inflammation of the orbit. | 21626164 |
| Xanthogranulomatous inflammation | Altered Intercellular Communication | The left orbit was surgically debulked twice and histology revealed xanthogranulomatous inflammation, with the additional features of sclerosis, lymphoid aggregates and a prominent population of plasma cells. | 21626164 |
| Xanthogranulomatous inflammation | Altered Intercellular Communication | We propose that the overall disease is a novel variant of IgG4 sclerosing disease of the orbit and suggest that cases of histologically proven xanthogranulomatous inflammation should be stained for IgG4 if there is an accompanying plasma cell population. | 21626164 |
| Herpes Zoster Ophthalmicus, Inflammation | Altered Intercellular Communication | Herpes zoster ophthalmicus (HZO) occurs when inflammation spreads from the ganglion of Gasser to the ophthalmic branch of the trigeminal nerve. | 21626168 |
| Inflammation, Neoplasms | Altered Intercellular Communication | Nontraumatic brachial plexopathies may be caused by primary or secondary tumors, radiation or inflammation. | 21627017 |
| Inflammation, Demographics Domain, Diabetes Mellitus | Altered Intercellular Communication | It is well accepted that glycemic control in patients with diabetes mellitus (DM) is affected by systemic inflammation and oxidative stress. | 21627458 |
| Inflammation, Acute abscess | Altered Intercellular Communication | The biopsy sample was consistent with chronic non-specific inflammation in acute abscess. | 21628820 |
| Inflammation, Retinitis Pigmentosa, polychondritis, Cartilage | Altered Intercellular Communication | Relapsing polychondritis (RP) is a multiple system disease of unknown cause characterized by episodic inflammation of cartilage and potentially progressive degeneration of cartilaginous tissue. | 21629081 |
| Orbital Cellulitis | Altered Intercellular Communication | A total of 97 patients were admitted with a diagnosis of orbital inflammation/cellulitis, of whom 49 patients had clinical and/or radiographic evidence of orbital cellulitis. | 21629136 |
| Proteinuria, Toxic effect, Inflammatory disease of mucous membrane, Diarrhea, Bothered by Vomiting, Hypertension, CTCAE, Headache, Anorexia, Nausea, Dry skin, Weight decreased, Dermatitis acneiform, Pruritus, Fatigue | Altered Intercellular Communication | Toxicities observed were manageable; the most common treatment-related toxicities (>10% of patients) were fatigue, diarrhoea, anorexia, increase in aspartate aminotransferase and alanine aminotransferase, acneiform dermatitis, headache, mucosal inflammation, nausea, dry skin, vomiting, hypertension, pruritus, proteinuria and weight loss. | 21629245 |
| Alzheimers Disease", Data types - Address | Altered Intercellular Communication | Cholinesterase inhibitors are commonly prescribed to patients with Alzheimer's disease (AD) to enhance cholinergic neurotransmission. | 21630031 |
| Inflammation, Sarcoidosis | Altered Intercellular Communication | Sarcoidosis is a systemic granulomatous inflammation that occurs as a result of disturbed immune regulation in individuals exposed to certain environmental agents. | 21630202 |
| Necrotizing granulomatous inflammation, Granuloma | Altered Intercellular Communication | The existence of epithelioid histiocytes and/or giant cells that formed granulomas was used as a cytological diagnostic criterion for chronic granulomatous inflammation. | 21630202 |
| Necrotizing granulomatous inflammation, Sarcoidosis | Altered Intercellular Communication | A total of 31 out of the 38 patients were diagnosed as sarcoidosis with clinical, radiological and microbiological findings, after chronic granulomatous inflammation was considered by cytologic assessment. | 21630202 |
| Necrotizing granulomatous inflammation | Altered Intercellular Communication | We highlighted the adequacy criteria of cytological sampling and the encountered cytological findings of chronic granulomatous inflammation. | 21630202 |
| Mediastinal lymphadenopathy, Granulomatous inflammation, Lymphoma | Altered Intercellular Communication | EBUS-TBNA is a minimally invasive procedure which provides sufficient sample for definitive primary diagnosis and classification of malignant lymphoma and granulomatous inflammation in patients with mediastinal lymphadenopathy. | 21630485 |
| Angioedema, Communicable Diseases, Irritation - emotion, Airway structure | Altered Intercellular Communication | Long-term therapy with angiotensin-converting enzyme inhibitors could be associated with delayed angioedema, especially in patients with inflammation of airways caused by infection or chronic irritation. | 21630523 |
| Inflammation, Impaired mitochondrial function, Sarcopenia | Altered Intercellular Communication | The main mechanisms underlying sarcopenia have not been determined conclusively, but chronic inflammation, apoptosis, and impaired mitochondrial function are believed to play important roles. | 21631380 |
| Inflammation | Altered Intercellular Communication | Our findings for sTNF-R1 and sCD27, possible markers for inflammatory and B-cell stimulatory states, respectively, support a role for subclinical inflammation and chronic B-cell stimulation in lymphomagenesis. | 21632552 |
| Acute Coronary Syndrome, Dying Process, Inflammation | Altered Intercellular Communication | Fear of dying and inflammation following acute coronary syndrome. | 21632602 |
| Inflammation, Dying Process, Injury of cardiac valve | Altered Intercellular Communication | Intense distress and fear of dying and heightened inflammation may be related manifestations of an acute biobehavioural response to severe cardiac injury, and have implications for prognostically significant biological risk processes. | 21632602 |
| methyldopa, Inflammation | Altered Intercellular Communication | There is increasing evidence that inflammation and immune-mediated processes (complement activation) play an important role in age-related macular degeneration (AMD) pathogenesis. | 21633121 |
| methyldopa, Inflammation | Altered Intercellular Communication | A genetic variation in the gene encoding complement factor H (CFH) and plasma levels of C-reactive protein (CRP), a systemic marker of subclinical inflammation, have consistently been shown to be associated with an increased risk for AMD. | 21633121 |
| methyldopa, Inflammation | Altered Intercellular Communication | This study supports the hypothesis that inflammation and immune-mediated mechanisms are involved in the pathogenesis of AMD. | 21633121 |
| Inflammation | Altered Intercellular Communication | Caspase-8 (CASP8) involved in apoptosis plays an important role in mediating the normal regulation of cell proliferation, differentiation, inflammation, and homeostasis of multicellular organisms. | 21633787 |
| Aortic Aneurysm, Abdominal | Altered Intercellular Communication | Inflammation within the abdominal aortic wall is generally considered a very significant ethiopathogenic factor in the development of abdominal aortic aneurysms. | 21634132 |
| Inflammation | Altered Intercellular Communication | Proinflammatory cytokines are important mediators of inflammation within the abdominal aortic wall. | 21634132 |
| Inflammation | Altered Intercellular Communication | Age-associated development of inflammation in Wistar rats: Effects of caloric restriction. | 21635187 |
| Inflammation, Diabetes Mellitus | Altered Intercellular Communication | Insulin resistance and type 2 Diabetes have been associated to a low grade of inflammation and their prevalence increase with ageing. | 21635187 |
| Inflammation, Hypothalamic structure | Altered Intercellular Communication | To analyse the development of inflammation in adipose tissue, liver, muscle and hypothalamus during ageing and the effects of caloric restriction. | 21635187 |
| Inflammation | Altered Intercellular Communication | These data indicate a role of adiposity in the development of inflammation and insulin resistance during ageing. | 21635187 |
| ARCN1 gene, Inflammation, Chronic Obstructive Airway Disease, physiopathological | Altered Intercellular Communication | Discrepancies exist regarding the involvement of cellular inflammation and apoptosis in the muscle dysfunction of chronic obstructive pulmonary disease (COPD) patients with preserved body composition. | 21636562 |
| ARCN1 gene, Inflammation, physiopathological | Altered Intercellular Communication | In severe COPD patients with preserved body composition, while increased apoptotic nuclei seems to be a contributor to their muscle dysfunction, cellular inflammation does not. | 21636562 |
| Inflammation, Congenital Heart Defects, Lupus Erythematosus, Systemic | Altered Intercellular Communication | In stable SLE patients pericardial and valve abnormalities may be associated with markers of an ongoing inflammation. | 21636627 |
| Gastrointestinal inflammation | Altered Intercellular Communication | The MUC13 cell-surface mucin protects against intestinal inflammation by inhibiting epithelial cell apoptosis. | 21636645 |
| Inflammation, Squamous cell carcinoma | Altered Intercellular Communication | For pathology results, 1 patient had inflammation only, 1 had spindle cell cancer, and 15 had squamous cell cancer. | 21637051 |
| Inflammation, Ototoxicity, Demyelinating Diseases | Altered Intercellular Communication | Together, these results reveal that increased expression of the cystine/glutamate antiporter system x(c)- in MS provides a link between inflammation and excitotoxicity in demyelinating diseases. | 21639880 |
| Degenerative polyarthritis, Inflammation | Altered Intercellular Communication | Calcium-containing crystals are quite common in primary OA and they worsen or may cause OA through induction of inflammation by neutrophils. | 21640042 |
| Inflammation | Altered Intercellular Communication | Colchicine inhibits urate-crystal and calcium-pyrophosphate (CPP) crystal induced inflammation and elastase, a matrix-metalloproteinase (MMP) that play a pivotal role in degenerative joint processes. | 21640042 |
| Inflammation, Hyperplasia, Atherosclerosis | Altered Intercellular Communication | Vascular lesions were categorized as showing intimal fibromuscular hyperplasia, atherosclerosis and/or inflammation. | 21640617 |
| Inflammation, Atheroma, Hyperplasia | Altered Intercellular Communication | Intramyocardial arteries showed primarily intimal fibromuscular hyperplasia and inflammation with no atheromas present. | 21640617 |
| Inflammation, Fibromuscular Dysplasia, Atherosclerosis | Altered Intercellular Communication | Lesions in the epicardial coronary arteries were composed of intimal fibromuscular hyperplasia, atherosclerosis and/or inflammation affecting one or more vascular layers (intima, media and adventitia). | 21640617 |
| Inflammation, Intimal proliferation | Altered Intercellular Communication | Both arteries and veins showed intimal hyperplasia and inflammation. | 21640617 |
| Inflammation, CAV1 gene, Vasculitis, CTCAE, Atherosclerosis | Altered Intercellular Communication | CAV is a pathologically multifaceted disorder that affects large and small epicardial coronary arteries of adults and children, with different types of lesions: intimal fibromuscular hyperplasia; atherosclerosis; and/or inflammation (vasculitis). | 21640617 |
| Inflammation, Venous Thromboembolism, vinyltriethoxysilane | Altered Intercellular Communication | Studies have established a relationship between inflammation and venous thromboembolism (VTE). | 21641019 |
| Inflammation, vinyltriethoxysilane | Altered Intercellular Communication | Though statins modulate inflammation, it is uncertain if they prevent VTE in heterogeneous populations. | 21641019 |
| Inflammation, Chronic sinusitis, Microbial Biofilms | Altered Intercellular Communication | Bacterial biofilms in chronic rhinosinusitis and their relationship with inflammation severity. | 21641137 |
| Inflammation, Heart failure, Bipolar Disorder | Altered Intercellular Communication | Depressive symptoms and inflammation in patients hospitalized for heart failure. | 21641350 |
| Inflammation, Heart failure, Bipolar Disorder | Altered Intercellular Communication | Depressive symptoms in patients with heart failure (HF) are common and might be associated with inflammation. | 21641350 |
| Inflammation, Bipolar Disorder | Altered Intercellular Communication | No studies have examined both the cross-sectional and prospective association between inflammation and depressive symptoms in patients with HF with adequate correction for disease severity. | 21641350 |
| Inflammation, Bipolar Disorder | Altered Intercellular Communication | Data from 517 patients hospitalized for HF from the COACH study were analyzed on inflammation markers (IL-6 and CRP) and depressive symptoms (Center for Epidemiological Studies Depression-Scale). | 21641350 |
| Inflammation, Bipolar Disorder | Altered Intercellular Communication | Structural equation modelling showed that the factor inflammation (including IL-6 and CRP) was associated with depressive symptoms (b = 0.18, P < .05) when left ventricular ejection fraction and plasma values brain natriuretic peptides were included in the model. | 21641350 |
| Inflammation, Bipolar Disorder | Altered Intercellular Communication | There is no clear relationship between inflammation at baseline and depressive symptoms during the 18 months of follow-up. | 21641350 |
| Inflammation, Villous atrophy | Altered Intercellular Communication | Many (54%) showed signs of inflammation in the biopsy, without villous atrophy. | 21641886 |
| Celiac Disease, Gastrointestinal symptom, Inflammatory disease of mucous membrane | Altered Intercellular Communication | Overt coeliac disease is seldom found behind persistent AGA-positivity, but this characteristic is associated with mucosal inflammation and gastrointestinal symptoms at least in HLA-positive individuals. | 21641886 |
| Inflammation, Disease remission | Altered Intercellular Communication | Future clinical trials should emphasize the treatment of patients who have objective evidence of inflammation in addition to symptoms of active disease. | 21642014 |
| Cessation of life, Inflammation, Kidney Failure, Chronic | Altered Intercellular Communication | Inflammation and asymmetric dimethylarginine for predicting death and cardiovascular events in ESRD patients. | 21642364 |
| Kidney Failure, Chronic, Inflammation, Atherosclerosis, Endothelial dysfunction, Cessation of life | Altered Intercellular Communication | Endothelial dysfunction as assessed by asymmetric dimethylarginine (ADMA) and inflammation has been consistently linked to atherosclerosis, death, and cardiovascular (CV) events in ESRD patients. | 21642364 |
| Cessation of life, Inflammation, Kidney Failure, Chronic | Altered Intercellular Communication | With crude and multiple Cox regression analyses, an interaction was found between inflammation biomarkers and ADMA for explaining death and CV events in ESRD patients. | 21642364 |
| Cessation of life, Inflammation, Kidney Failure, Chronic | Altered Intercellular Communication | These data support the hypothesis that inflammation amplifies the risk of death and CV events associated with high ADMA levels in ESRD. | 21642364 |
| Inflammation, Bacterial Infections | Altered Intercellular Communication | The discrimination of bacterial infections from sterile inflammatory processes is of great importance in the management of inflammation. | 21642882 |
| Inflammation | Altered Intercellular Communication | On initial presentation, the patient complained of progressively worsening left-sided coxalgia without localized or generalized inflammation. | 21645338 |
| Inflammation, Nerve Degeneration | Altered Intercellular Communication | Accordingly, PGRN-deficient mice have been demonstrated to develop enhanced inflammation and progressive neurodegeneration. | 21645364 |
| Inflammation, Nerve Degeneration | Altered Intercellular Communication | Since neurodegeneration might be negatively impacted by chronic inflammation, the possible influence of PGRN defects on inflammatory pathways appears to be of great relevance for the understanding of neurodegeneration pathogenic processes in those patients. | 21645364 |
| vascular inflammations, Osage language | Altered Intercellular Communication | This suggests that OSA could activate vascular inflammation in CAD patients despite current best practice medications. | 21646006 |
| Inflammation, Coronary Artery Disease | Altered Intercellular Communication | Enhanced inflammation in epicardial fat in patients with coronary artery disease. | 21646734 |
| Inflammation, Coronary Arteriosclerosis | Altered Intercellular Communication | Chronic inflammation in epicardial fat may influence the pathogenesis of coronary atherosclerosis. | 21646734 |
| Inflammation | Altered Intercellular Communication | CSS relapse may be linked to increased numbers of CD4+ T cells producing IL-25, which promotes Th2 inflammation, and to a decline in the Tr1 cell subpopulation resulting from lower IDO expression in monocytes. | 21646795 |
| Carcinoma of lung | Altered Intercellular Communication | Neutrophilic airways inflammation in lung cancer: the role of exhaled LTB-4 and IL-8. | 21649887 |
| Inflammation, Non-Small Cell Lung Carcinoma, Carcinoma of lung | Altered Intercellular Communication | The high concentrations of exhaled LTB-4 and IL-8 showed the presence of a neutrophilic inflammation in the airways of NSCLC patients and gave a further support to the inflammatory signalling in lung cancer. | 21649887 |
| Inflammation, Non-Small Cell Lung Carcinoma, Carcinoma of lung | Altered Intercellular Communication | The high concentrations of exhaled LTB-4 and IL-8 showed the presence of a neutrophilic inflammation in the airways of NSCLC patients and gave a further support to the inflammatory signalling in lung cancer. | 21649887 |
| Coughing, Airway structure | Altered Intercellular Communication | Serum LDH in chronic cough: a potential marker of airway inflammation. | 21651741 |
| Airway structure, Chronic cough | Altered Intercellular Communication | This rise is likely to be due to airway inflammation known to be associated with chronic cough. | 21651741 |
| Inflammation | Altered Intercellular Communication | Exposure to particulate matter (PM) may induce inflammation and oxidative stress in the airways. | 21651749 |
| Inflammatory abnormality of the eye | Altered Intercellular Communication | QuantiFERON-TB gold cut-off value: implications for the management of tuberculosis-related ocular inflammation. | 21652022 |
| Inflammatory abnormality of the eye | Altered Intercellular Communication | Ninety-six consecutive patients presenting with ocular inflammation between January and October 2007 were tested using QuantiFERON-TB Gold. | 21652022 |
| Inflammatory abnormality of the eye | Altered Intercellular Communication | Treatment was considered effective at the end of follow-up, in cases of no or a 2-point decrease of ocular inflammation (SUN criteria) and systemic corticosteroids stopped or tapered to 10 mg/day. | 21652022 |
| Inflammatory abnormality of the eye, Panuveitis, Scleritis, Uveitis | Altered Intercellular Communication | Types of ocular inflammation included scleritis (n = 7), panuveitis (n = 34), and posterior (n = 15), intermediate (n = 14), and anterior uveitis (n = 15). | 21652022 |
| Intraocular inflammation, Complication Aspects | Altered Intercellular Communication | A total of 126 patients (156 eyes) were evaluated for presence of CME, visual acuity, intraocular pressure, degree of intraocular inflammation, and the presence of ocular complications. | 21652023 |
| Communicable Diseases, Inflammation | Altered Intercellular Communication | Postoperative follow-up showed that the simultaneous everting sutures caused no problems with the cultivated oral mucosal epithelial sheet, and there were no severe complications such as infection or inflammation. | 21652025 |
| Myocarditis, CTCAE 5.0, Myocardium | Altered Intercellular Communication | Myocarditis, a general inflammatory condition of the heart muscle, can result from a variety of etiologies, the most common being viral. | 21652168 |
| Inflammation | Altered Intercellular Communication | Potential explanations for the increased risk of AF in CD include chronic inflammation and shared risk factors, but ascertainment bias may also have contributed. | 21653560 |
| Inflammation, Atherosclerosis | Altered Intercellular Communication | Dietary micronutrient intakes are associated with markers of inflammation but not with markers of subclinical atherosclerosis. | 21653577 |
| Inflammation, Atherosclerosis | Altered Intercellular Communication | Few studies have examined associations of dietary micronutrients with markers of inflammation and subclinical atherosclerosis. | 21653577 |
| Inflammation, Diabetes Mellitus, Atherosclerosis, Cardiovascular Diseases | Altered Intercellular Communication | Micronutrient intakes and markers of inflammation and subclinical atherosclerosis were studied in 5,181 participants from the Multi-Ethnic Study of Atherosclerosis who were aged 45-84 y and free of diabetes and cardiovascular disease. | 21653577 |
| Inflammation, Primary malignant neoplasm, Neoplasms | Altered Intercellular Communication | Accelerated aging in the tumor microenvironment: connecting aging, inflammation and cancer metabolism with personalized medicine. | 21654190 |
| Inflammation, Primary malignant neoplasm, Neoplasms | Altered Intercellular Communication | Here, we discuss how ROS signaling, NFkB- and HIF1-activation in the tumor microenvironment induces a form of "accelerated aging," which leads to stromal inflammation and changes in cancer cell metabolism. | 21654190 |
| Inflammation, Primary malignant neoplasm, Neoplasms | Altered Intercellular Communication | Thus, we present a unified model where aging (ROS), inflammation (NFkB) and cancer metabolism (HIF1), act as co-conspirators to drive autophagy ("self-eating") in the tumor stroma. | 21654190 |
| Inflammation, Primary malignant neoplasm | Altered Intercellular Communication | These findings have important new implications for personalized cancer medicine, as they link aging, inflammation and cancer metabolism with novel strategies for more effective cancer diagnostics and therapeutics. | 21654190 |
| Acute Lung Injury, Pneumonitis | Altered Intercellular Communication | EPA/GLA has anti-inflammatory benefits, as evidenced by its association with reduction in pulmonary inflammation, improvement in oxygenation and improved clinical outcomes in patients with severe forms of acute lung injury. | 21658240 |
| Cholangiocarcinoma, Primary malignant neoplasm, Liver carcinoma, FAM126A gene, Abdominal Infection, Liver Cirrhosis | Altered Intercellular Communication | Overall, the predominant risk factor was hepatocellular carcinoma (HCC) (52.5%), followed by liver cirrhosis without cancer (9.3%), abdominal infection/inflammation (9.3%), cholangiocarcinoma (8.2%), and abdominal intervention (7.7%). | 21658275 |
| Liver Abscess, Pancreatitis, Tuberculosis, Splenic abscess, Omphalitis of the newborn, Cholecystitis, Cholangitis | Altered Intercellular Communication | A variety of abdominal infections/inflammations were also found including liver abscess, splenic abscess, cholangitis, cholecystitis, pancreatitis, omphalitis, and abdominal tuberculosis. | 21658275 |
| Chlamydia trachomatis, Inflammatory abnormality of the eye | Altered Intercellular Communication | Molecular approach by PCR is the best method to detect the presence of Chlamydia trachomatis and to define the true agent of ocular bacterial inflammation. | 21658303 |
| methyldopa, Inflammation | Altered Intercellular Communication | In atrophic AMD, drugs attempt to spare the photoreceptors and the retinal pigment epithelium to prevent the oxidative damages or to suppress the inflammation process. | 21658792 |
| Inflammation | Altered Intercellular Communication | Mortality in long-term hemodialysis patients is high, mostly attributed to cardiovascular events, and may be related to chronic inflammation. | 21658827 |
| Cessation of life, Inflammation | Altered Intercellular Communication | Higher dietary omega-6 to omega-3 ratio appears to be associated with both worsening inflammation over time and a trend toward higher death risk in hemodialysis patients. | 21658827 |
| Inflammation, Anemia, Hematologic Neoplasms | Altered Intercellular Communication | Anemia etiologies included iron deficiency anemia at 25.3%, anemia of chronic inflammation at 9.8%, and hematologic malignancy in 7.5%. | 21659341 |
| Inflammation, Bone structure of calcaneum | Altered Intercellular Communication | Infected and healthy cancellous bone of the calcaneus is removed to eradicate all possible foci that maintain inflammation. | 21659847 |
| ARCN1 gene, Chronic Obstructive Airway Disease, Airway structure | Altered Intercellular Communication | Patients with chronic obstructive pulmonary disease (COPD) are prone to clinical exacerbations that are associated with increased airway inflammation, a potent pro-thrombotic stimulus. | 21660493 |
| Inflammation, Blood coagulation, Exacerbation | Altered Intercellular Communication | Elevation of IL-6, vWF, D-D and F1+2 levels during COPD exacerbations implies a strict association between acute inflammation, endothelial activation and clotting initiation. | 21660493 |
| Inflammation, Coronary Artery Disease | Altered Intercellular Communication | The markers of inflammation and (apo)lipoproteins are associated with coronary artery disease (CAD). | 21660913 |
| Inflammation, Hypotension, CTCAE, Abdominal rebound tenderness, Anemia, Tachycardia by ECG Finding | Altered Intercellular Communication | A 47-year old man presented with abdominal rebound tenderness, hypotension and tachycardia, anemia, and elevated markers of inflammation. | 21661368 |
| Inflammation, Hemorrhage, granulocyte, Necrosis | Altered Intercellular Communication | Histologic specimen showed full-thickness nonspecific inflammation of the intestinal wall with granulocytic infiltration, hemorrhage and necrosis. | 21661368 |
| Inflammation, Vasculitis, CTCAE | Altered Intercellular Communication | Histological analysis of excised appendix showed inflammation but without signs typical for vasculitis. | 21661371 |
| Inflammation, polyps, Meckel Diverticulum, Neoplasms, Ulcer, Angiodysplasia, Crohn Disease | Altered Intercellular Communication | These lesions were small-intestinal ulcers, Crohn's disease, chronic inflammation, Meckel's diverticulae, angiodysplasia, polyps, ulcerative lipoma and tumor. | 21661416 |
| helium, Inflammation, Hepatic Encephalopathy | Altered Intercellular Communication | It has been suggested that the presence of inflammation may accentuate the neuropsychologic alterations in hepatic encephalopathy (HE). | 21661419 |
| Inflammation, Liver Cirrhosis | Altered Intercellular Communication | There is an inflammatory response in the presence of cirrhosis and HE; and IL-18 may play a role in the perpetuation of chronic inflammation. | 21661419 |
| Communicable Diseases, Inflammation | Altered Intercellular Communication | No adverse events, such as infection, persistent inflammation, or abutment screw loosening, occurred. | 21661660 |
| Intraocular inflammation | Altered Intercellular Communication | Although the pathogenesis of bone formation in choroidal osteoma remains uncertain, intraocular inflammation might be one cause. | 21661667 |
| Inflammation, Fever, CTCAE, Vasospasm | Altered Intercellular Communication | Further studies are needed to determine if treatments targeting fever and inflammation may be effective in reducing the incidence of vasospasm following severe TBI. | 21663415 |
| Peripheral Vascular Diseases, Inflammation | Altered Intercellular Communication | The role of combined assessment of defense against oxidative stress and inflammation in the evaluation of peripheral arterial disease. | 21663591 |
| Inflammation | Altered Intercellular Communication | High sensitivity C-reactive protein (hsCRP) is an acute phase reactant and a sensitive marker of inflammation. | 21663637 |
| Airway structure | Altered Intercellular Communication | The epithelial senescence was accompanied by p38 MAPK-dependent airway inflammation. | 21663649 |
| Airway structure, Inflammation, ARCN1 gene | Altered Intercellular Communication | Senescence of airway epithelial cells impairs repair processes and exacerbates p38 MAPK-dependent inflammation after airway injury, and it may contribute to the pathogenesis of COPD. | 21663649 |
| Communicable Diseases, Inflammation, Prostate carcinoma, Malignant Neoplasms | Altered Intercellular Communication | Recent epidemiologic, genetic, and molecular studies suggest infection and inflammation initiate certain cancers, including cancers of the prostate. | 21663671 |
| Inflammation, Abdominal Pain | Altered Intercellular Communication | Vaginal discharge, cervical inflammation and abdominal pain differed significantly in relation to age. | 21663876 |
| Inflammation, Paratuberculosis | Altered Intercellular Communication | paratuberculosis (Map) is the causative agent of Johne's disease, a chronic inflammation of ruminants' intestine. | 21664191 |
| Inflammation, Unipolar Depression, Coronary heart disease | Altered Intercellular Communication | Inflammation and treatment response to sertraline in patients with coronary heart disease and comorbid major depression. | 21665007 |
| Inflammation, Depressed mood, Choline Dehydrogenase, Mitochondrial | Altered Intercellular Communication | Studies in depressed patients without CHD suggest that elevated markers of inflammation predict poor response to treatment. | 21665007 |
| Inflammation, Unipolar Depression, Choline Dehydrogenase, Mitochondrial | Altered Intercellular Communication | We therefore studied the relationship between pretreatment markers of inflammation and treatment response in patients with CHD and major depression. | 21665007 |
| Inflammation, Depression, CTCAE | Altered Intercellular Communication | Similarly, depression remitters (BDI-II <=8 at post-treatment) did not differ from non-remitters on the three baseline inflammation markers. | 21665007 |
| Inflammation, Pancreatic carcinoma | Altered Intercellular Communication | Pancreatitis-induced inflammation contributes to pancreatic cancer by inhibiting oncogene-induced senescence. | 21665147 |
| Inflammation, Neoplasms | Altered Intercellular Communication | The pre-operative biopsy taken after 3 months showed chronic inflammation and cytomegalovirus inclusions, but no tumour. | 21665860 |
| Keratitis, "Moorens ulcer | Altered Intercellular Communication | To evaluate the extent of corneal inflammation and the response to treatment in patients with Mooren's ulcer, by in vivo confocal microscopy (IVCM). | 21666242 |
| Autoimmune Hypophysitis, Autoimmune endocrine disease, Lymphocytic infiltration | Altered Intercellular Communication | Recurrent autoimmune hypophysitis is a rare autoimmune endocrine disease involving lymphocytic infiltration and chronic pituitary inflammation. | 21666339 |
| Inflammation, Periprosthetic Fractures | Altered Intercellular Communication | Histological analysis of periprosthetic tissue in all 3 cases identified characteristic features such as perivascular lymphocytic aggregates and chronic inflammation consistent with aseptic lymphocytic vasculitis-associated lesions (ALVAL). | 21667724 |
| Wounds and Injuries | Altered Intercellular Communication | Predisposing factors are: traumas, inflammatory conditions and biomechanics alterations. | 21669155 |
| Colorectal Carcinoma, Gastrointestinal inflammation | Altered Intercellular Communication | We had a particular interest in patients suffering from intestinal inflammation as this may stimulate endogenous NOC formation, and consequently predispose to CRC risk. | 21669488 |
| Inflammatory Bowel Diseases, Inflammation, Ulcerative Colitis, Irritable Bowel Syndrome | Altered Intercellular Communication | Inflammatory bowel disease (IBD) patients diagnosed with ulcerative colitis and irritable bowel syndrome patients without inflammation, serving as controls, were therefore recruited. | 21669488 |
| Inflammatory Bowel Diseases, Inflammation | Altered Intercellular Communication | However, fecal NOC levels were slightly but not significantly increased in IBD patients, suggesting that inflammation did not strongly stimulate NOC formation. | 21669488 |
| Rheumatoid Arthritis, bone destruction, Autoimmune reaction | Altered Intercellular Communication | Collectively, our data suggest that systemic IL-23 exposure induces the expansion of a myeloid lineage osteoclast precursor, and targeting IL-23 pathway may combat inflammation-driven bone destruction as observed in rheumatoid arthritis and other autoimmune arthritides. | 21670317 |
| Inflammation, Albuminuria, Demographics Domain | Altered Intercellular Communication | Rosuvastatin administration reduced albuminuria, serum cystatin C levels, and inflammation, and improved lipid profiles, regardless of the presence or absence of DM, and the degree of the eGFR. | 21670545 |
| Inflammation, Cerebral Infarction | Altered Intercellular Communication | High serum antibody titers to P. gingivalis SU63 could be a predictor of cerebral infarction in Japanese men independent of traditional risk factors and inflammation. | 21670558 |
| Celiac Disease, Gastritis, Esophagitis, Inflammatory Bowel Diseases | Altered Intercellular Communication | Few Foxp3(+) cells were found in controls and inflammatory conditions (oesophagitis, gastritis, coeliac disease, inflammatory bowel disease); in preneoplastic and neoplastic conditions the number of Foxp3(+) cells was significatively increased. | 21670722 |
| Inflammation, Carcinogenesis | Altered Intercellular Communication | Neutrophil gelatinase-associated lipocalin (NGAL) is multi-functional protein, released from activated neutrophils, with roles in inflammation, immune function, and carcinogenesis. | 21670771 |
| Inflammation, pars defect | Altered Intercellular Communication | To evaluate the inflammation around the pars defects, short time inversion recovery (STIR) MRI was performed along with the sagittal section. | 21671077 |
| Inflammation, pars defect | Altered Intercellular Communication | Inflammation (i.e., fluid collection) was observed in all 12 pars defects in six subjects at the pseudoarthrotic pars defects. | 21671077 |
| Inflammation, pars defect, Facet joint structure | Altered Intercellular Communication | The present study showed that inflammation was always present at the pars defects and in some cases at the adjoining facet joints. | 21671077 |
| Inflammation, Facet joint structure | Altered Intercellular Communication | Thus, it is not difficult to understand how, during sports activity, inflammation may first occur at the pseudoarthrotic site and then spread to the adjoining facet joints. | 21671077 |
| Inflammation, Metabolic Syndrome X, ETV3 wt Allele | Altered Intercellular Communication | Abstract Background: Chronic inflammation and oxidative stress are associated with the development of metabolic syndrome (MetS). | 21671781 |
| Inflammation | Altered Intercellular Communication | We hypothesized that cardiac resynchronization therapy (CRT) improves cardiac sympathetic nervous dysfunction and systemic inflammation. | 21671958 |
| Inflammation | Altered Intercellular Communication | Our results demonstrated that cardiac sympathetic nervous dysfunction and systemic inflammation were improved in responder HF patients to CRT. | 21671958 |
| Inflammation | Altered Intercellular Communication | Furthermore, the reduction in systemic inflammation was associated with the improvement in cardiac sympathetic nervous dysfunction. | 21671958 |
| Inflammation | Altered Intercellular Communication | The sera were analysed with respect to biochemical parameters of systemic inflammation and liver function and to the presence of antibodies to nuclear antigens (ANA), mitochondria (AMA) and smooth muscle (SMA). | 21671974 |
| Dermatitis | Altered Intercellular Communication | These proteins were upregulated in cell populations that are critically involved in the pathogenesis of chronic skin inflammation, such as keratinocytes, macrophages in deep dermis and cells at the perivascular/endothelial area. | 21672030 |
| Psoriasis, Dermatitis | Altered Intercellular Communication | We conclude that interactions between TL1A and its two receptors may be involved in the pathogenesis of chronic skin inflammation that takes place in psoriasis. | 21672030 |
| Inflammation | Altered Intercellular Communication | Stress and inflammation reduce brain-derived neurotrophic factor expression in first-episode psychosis: a pathway to smaller hippocampal volume. | 21672499 |
| Inflammation Mediators, Traumatic injury | Altered Intercellular Communication | A linear regression analysis in patients showed that a history of childhood trauma and high levels of recent stressors predicted lower BDNF expression through an inflammation-mediated pathway (adjusted R(2) = 0.23, P = .009). | 21672499 |
| Data types - Address, Dermatitis | Altered Intercellular Communication | Skin colonization with S aureus is prevalent in children and adults with AD, and can aggravate skin inflammation. | 21673210 |
| Inflammation, Metabolic Syndrome X | Altered Intercellular Communication | Glucokinase regulatory protein genetic variant interacts with omega-3 PUFA to influence insulin resistance and inflammation in metabolic syndrome. | 21674002 |
| Inflammation, Sacroiliac joint structure, Peripheral, Spondylitis | Altered Intercellular Communication | Ankylosing spondylitis (AS) is a chronic inflammation of the sacroiliac joints, spine and peripheral joints. | 21674042 |
| Granulomatous inflammation, Vasculitis, CTCAE, Necrosis | Altered Intercellular Communication | Cardinal histologic features include a necrotizing vasculitis involving small vessels, extensive "geographic" necrosis, and granulomatous inflammation. | 21674414 |
| Inflammation, Neoplasms | Altered Intercellular Communication | Substantial evidence indicates that inflammation is a critical component of tumor progression. | 21674477 |
| Inflammation, Necrosis, hydrocortisone, Insemination, Artificial, Homologous, Interface hepatitis | Altered Intercellular Communication | Interface hepatitis, focal necrosis, and portal inflammation were present in all evaluated cases, but were more severe in AIH (P < 0.05) than DILI (HC). | 21674554 |
| Inflammation, Canalicular cholestasis, Insemination, Artificial, Homologous | Altered Intercellular Communication | A model combining portal inflammation, portal plasma cells, intra-acinar lymphocytes and eosinophils, rosette formation, and canalicular cholestasis yielded an area under the receiver operating characteristic curve (AUROC) of 0.90 in predicting DILI (HC) versus AIH. | 21674554 |
| Inflammation, Insemination, Artificial, Homologous | Altered Intercellular Communication | All Ishak inflammation scores were more severe in AIH than DILI (CS) (P <= 0.05). | 21674554 |
| Inflammation, Fibrosis Assessment, Cholestasis, Insemination, Artificial, Homologous | Altered Intercellular Communication | The combination of portal inflammation, fibrosis, portal neutrophils and plasma cells, and intracellular (hepatocellular) cholestasis yielded an AUC of 0.91 in predicting DILI (CS) versus AIH. | 21674554 |
| Inflammation, Erythema | Altered Intercellular Communication | Colonoscopy demonstrated diffuse inflammation with erythema, friability, and shallow ulcerations in the rectum and colon. | 21675504 |
| Inflammation | Altered Intercellular Communication | BAC causes similar X-ray changes to COP and inflammation accompanying BAC can also respond to corticosteroids, which may lead to delay in the diagnosis of BAC associated with COP. | 21675931 |
| Inflammation | Altered Intercellular Communication | Presence of aortic inflammation was ascertained through linkage to a nationwide pathology registry. | 21676237 |
| Inflammation, Connective Tissue Diseases, Diabetes Mellitus | Altered Intercellular Communication | Predictors of inflammation included connective tissue disease, diabetes, advanced age, and aortic valve pathology. | 21676237 |
| Inflammation, Chronic Kidney Diseases, Atherosclerosis | Altered Intercellular Communication | Chronic Kidney Disease (CKD) patients present high levels of electronegative LDL (LDL-) that can modulate the expression of molecules involved in inflammation and it is closely linked to atherosclerosis. | 21676364 |
| Inflammation, Chronic Kidney Diseases, Atherosclerosis | Altered Intercellular Communication | The association between LDL(-) and inflammation and the lower levels of anti-LDL(-) autoantibodies are important risk factors related to atherosclerosis in CKD. | 21676364 |
| ARCN1 gene, Inflammation | Altered Intercellular Communication | Cigarette smoke is the main cause of inflammation in COPD. | 21676518 |
| Inflammation, Atherosclerosis | Altered Intercellular Communication | Inflammation is a critical contributing factor to the development and progression of atherosclerosis. | 21676590 |
| Communicable Diseases, Osteonecrosis of Jaw, Inflammation, Necrosis | Altered Intercellular Communication | The predilection for mandibular molar and premolar regions, and the infectious conditions that often precede the onset of ONJ support recent pathogenesis theories stating that local inflammation and associated pH-changes may trigger the release and activation of nitrogen-containing bisphosphonates ultimately resulting in necrosis. | 21676622 |
| Masked Hypertension, Inflammation, ciliary vesicle | Altered Intercellular Communication | Masked-hypertension was identified in 58% of African Americans which suggests that a masking phenomenon may exist in a sub-group of prehypertensives who also seem to have a diminished endothelial function that could be mediated by an elevated subclinical inflammation leading to the increased CV disease. | 21677701 |
| Primary malignant neoplasm, Chronic disease, Obesity | Altered Intercellular Communication | Obesity is associated with a variety of chronic diseases, including cancer, which may partly be explained by its influence on sex steroid hormone concentrations. | 21678033 |
| Inflammation, Ulcerative Colitis | Altered Intercellular Communication | UC was also subgrouped according to the severity of inflammation. | 21678108 |
| Inflammation, Ulcerative Colitis | Altered Intercellular Communication | In contrast, the mucosal up-regulation of MMP-9 correlated with the severity of inflammation in UC. | 21678108 |
| ARCN1 gene, Inflammation | Altered Intercellular Communication | Relation between physical capacity, nutritional status and systemic inflammation in COPD. | 21679348 |
| ARCN1 gene, Inflammation, Chronic Obstructive Airway Disease, Fat-free mass, Weight decreased | Altered Intercellular Communication | Decreased physical capacity, weight loss, fat-free mass depletion and systemic inflammation are frequently observed in patients with chronic obstructive pulmonary disease (COPD). | 21679348 |
| ARCN1 gene, Inflammation | Altered Intercellular Communication | Our aim was to examine relations between physical capacity, nutritional status, systemic inflammation and disease severity in COPD. | 21679348 |
| Inflammation, Chronic Obstructive Airway Disease | Altered Intercellular Communication | Physical capacity in chronic obstructive pulmonary disease is related to lung function, body composition and systemic inflammation. | 21679348 |
| Inflammation, Atherosclerosis | Altered Intercellular Communication | Transforming growth factor-b1 (TGF-b1) is a multifunctional cytokine involved in inflammation and pathogenesis of atherosclerosis. | 21679448 |
| Airway structure, Asthma | Altered Intercellular Communication | Exhaled nitric oxide (NO) production is increased in asthma and reflects the degree of airway inflammation. | 21679473 |
| Inflammation, Nasopharyngeal carcinoma | Altered Intercellular Communication | The patients were divided into two groups depending on the pathological results: nasopharyngeal carcinoma (NPC) and lymphoid hyperplasia/chronic inflammation (LH). | 21679514 |
| Inflammation, Aortic Valve Stenosis | Altered Intercellular Communication | Because fluorodeoxyglucose positron emission tomography (FDG-PET) imaging provides a noninvasive index of inflammation, we sought to assess whether FDG uptake in the aortic valve (AV) is increased in aortic stenosis (AS). | 21679852 |
| Inflammation, Late stage | Altered Intercellular Communication | This study supports the hypothesis that AS is an inflammatory condition and suggests that inflammation may be reduced in late-stage disease. | 21679852 |
| Inflammation, Late stage | Altered Intercellular Communication | This study supports the hypothesis that AS is an inflammatory condition and suggests that inflammation may be reduced in late-stage disease. | 21679852 |
| Inflammatory abnormality of the eye, Primary anterior uveitis, Uveitis | Altered Intercellular Communication | Patients with primary anterior uveitis presenting to 1 of 4 academic ocular inflammation subspecialty practices achieving remission of the primary episode within 90 days of initial uveitis diagnosis. | 21680024 |
| Inflammation, Tumor necrosis, Retinoblastoma | Altered Intercellular Communication | Histopathology of the enucleated eye revealed diffuse inflammation and tumor necrosis but with absence of malignant retinoblastoma cells. | 21680213 |
| Inflammation, NCI CTEP SDC Retinoblastoma Sub-Category Terminology | Altered Intercellular Communication | The patient is presumed to have had retinoblastoma that underwent autoinfarction, leading to secondary inflammation. | 21680213 |
| Inflammation, Vascular calcification, Plaque, Atherosclerotic | Altered Intercellular Communication | Correlation of inflammation assessed by 18F-FDG PET, active mineral deposition assessed by 18F-fluoride PET, and vascular calcification in atherosclerotic plaque: a dual-tracer PET/CT study. | 21680686 |
| Inflammation, Calcinosis, Plaque, Atherosclerotic | Altered Intercellular Communication | Formation and progression of atherosclerotic plaque is a dynamic and complex process involving various pathophysiologic steps including inflammation and calcification. | 21680686 |
| ARCN1 gene, Inflammation, Chronic Obstructive Airway Disease | Altered Intercellular Communication | Exacerbations of chronic obstructive pulmonary disease (COPD) are heterogeneous with respect to inflammation and etiology. | 21680942 |
| ARCN1 gene, Exacerbation, Airway structure | Altered Intercellular Communication | Investigate biomarker expression in COPD exacerbations to identify biologic clusters and determine biomarkers that recognize clinical COPD exacerbation phenotypes, namely those associated with bacteria, viruses, or eosinophilic airway inflammation. | 21680942 |
| Hepatic, Inflammation, Cholestasis, Cholestanes | Altered Intercellular Communication | CK-7 expression was evaluated as a marker of cholestasis (cholestatic pattern) and inflammation (hepatitic pattern). | 21681009 |
| Airway structure, Bronchiolitis | Altered Intercellular Communication | To evaluate the existence of airway inflammation and characteristic of RSV bronchiolitis, we analyzed and compared the concentrations of eosinophilic cationic protein (ECP) in nasal fluid and plasma. | 21681019 |
| Airway structure, Infancy | Altered Intercellular Communication | The monitoring of ECP concentration in nasal fluid may be useful for evaluating leukocyte (including eosinophils and neutrophils)-mediated airway inflammation during infancy and its severity. | 21681019 |
| Inflammation, Neoplasms, Infection, Anemia, Inflammatory disorder, Thrombocytosis | Altered Intercellular Communication | Thrombocytosis was not a non-specific marker of inflammation, because uncomplicated infections and most admission causes were not associated with thrombocytosis, except for inflammatory rheumatic diseases (6% versus 1%), along with anemia (9.4% versus 2.5%) and tumor comorbidity (25% versus 14%). | 21681080 |
| Inflammation, Thrombocytosis | Altered Intercellular Communication | Thrombocytosis is not a simple marker of inflammation. | 21681080 |
| Inflammation, Microscopic hematuria, physiopathological | Altered Intercellular Communication | Laboratory data revealed signs of inflammation, glomerular dysfunction with microhaematuria, and positive myeloperoxidase-antineutrophil cytoplasmic antibodies. | 21681367 |
| Acute hepatopathy, Hepatitis | Altered Intercellular Communication | SNMC can be used safely and be useful for patients with difficult-to-diagnose acute liver disease as an 'initial' treatment tool to improve liver inflammation before starting disease-specific treatments. | 21681505 |
| primary infection nos, Pneumocystis jiroveci, Upper Respiratory Infections | Altered Intercellular Communication | Primary infection with Pneumocystis jirovecii in small children may cause inflammation of the respiratory tract which requires hospitalization. | 21682093 |
| Virus Diseases | Altered Intercellular Communication | The obtained results confirm that primary P. jirovecii infections may occur in the form of acute respiratory tract inflammations suggesting a viral infection. | 21682093 |
| Communicable Diseases, Inflammation | Altered Intercellular Communication | Two distal screws loosened (revised with new distal screws), and one early inflammation and one late infection occurred (revised to arthrodesis). | 21682612 |
| Sepsis, Communicable Diseases, Systemic Inflammatory Response Syndrome | Altered Intercellular Communication | Sepsis is a complex immunological response to infection characterized by early hyper-inflammation followed by severe and protracted immunosuppression, suggesting that a multi-marker approach has the greatest clinical utility for early detection, within a clinical environment focused on Systemic Inflammatory Response Syndrome (SIRS) differentiation. | 21682927 |
| Sepsis, Inflammation, Traumatic injury | Altered Intercellular Communication | Thus, the primary objective was to apply these gene expression biomarkers to distinguish patients with sepsis from those who had undergone major open surgery and had clinical outcomes consistent with systemic inflammation due to physical trauma and wound healing. | 21682927 |
| hydrocortisone, Inflammation | Altered Intercellular Communication | Quantitative PCR results suggest the capacity for this test to differentiate severe systemic inflammation from HC is 92%. | 21682927 |
| Abnormal cornea morphology, Conjunctivitis | Altered Intercellular Communication | Relief of symptoms, conjunctival inflammation, corneal epithelial abnormalities, and visual acuity were compared before and after surgeries as outcome measures. | 21683334 |
| Conjunctivitis | Altered Intercellular Communication | Conjunctival inflammation was reduced markedly in 19 eyes (86.4%). | 21683334 |
| Data types - Address | Altered Intercellular Communication | These novel findings suggest that distinct Ab oligomers induce impairment of cholinergic neurotransmission in AD pathogenesis. | 21683475 |
| Inflammation, Xerostomia, Chronic Kidney Diseases | Altered Intercellular Communication | The aim of this observational study was to investigate the relationship between DNA damage in minor accessory salivary glands, hyposalivation, and inflammation in patients with chronic kidney disease (CKD). | 21684780 |
| Inflammation, Hepatobiliary Disorder, Liver Cirrhosis | Altered Intercellular Communication | In chronic hepatitis C, selective expansion of peripheral T-regs in patients with normal aminotransferases and advanced disease suggests that, though a continual low level inflammation does not prevent liver disease progression, once cirrhosis has developed it may represent an attempt to prevent immuno-mediated decompensation. | 21684822 |
| Inflammation, Pterygia | Altered Intercellular Communication | The high prediction accuracy based on phospho- and total protein levels and phospho/total ratio of ERK1/2, p38, JNK, and IkB-a suggests these molecules as potential biomarkers of inflammation in pterygia. | 21685342 |
| Inflammation, hepcidin | Altered Intercellular Communication | The transcriptional mechanism of hepcidin in hepatocytes during inflammation is mediated via the IL-6/STAT3 pathway. | 21685415 |
| Inflammation, Depression, CTCAE, Coronary heart disease | Altered Intercellular Communication | Some studies have reported that depression is associated with higher levels of C-reactive protein (CRP) a marker of systemic inflammation that has been shown consistently to predict coronary heart disease risk. | 21685519 |
| Inflammation, Atherosclerosis | Altered Intercellular Communication | Inflammation, the key regulator of CRP synthesis, plays a pivotal role in atherothrombotic cardiovascular disease. | 21685519 |
| Inflammation | Altered Intercellular Communication | Positive findings of CD including active inflammation, stricturing, and penetrating disease were more frequent in MREs ordered to evaluate obstructive symptoms (87.5%) compared other indications (58.1%, p = 0.001). | 21688128 |
| Inflammation, Primary malignant neoplasm | Altered Intercellular Communication | Results suggest that MQ benefits cancer patients' self-reported CF, QOL, and inflammation. | 21688163 |
| Inflammation, MZB1 gene | Altered Intercellular Communication | MEDA-7 is a hormone-regulated adipokine/proinflammatory cytokine that is implicated in causing chronic inflammation, affecting cellular expansion and blunting insulin response in adipocytes. | 21688198 |
| Inflammation, MZB1 gene | Altered Intercellular Communication | MEDA-7 is a hormone-regulated adipokine/proinflammatory cytokine that is implicated in causing chronic inflammation, affecting cellular expansion and blunting insulin response in adipocytes. | 21688198 |
| Asthmatic Airway Remodeling | Altered Intercellular Communication | Eosinophils play a pivotal role in asthmatic airway inflammation. | 21690039 |
| ARCN1 gene, Inflammation, Exacerbation | Altered Intercellular Communication | Rhinovirus (RV)-induced chronic obstructive pulmonary disease (COPD) exacerbations exhibit TH(2)-like inflammation. | 21691053 |
| Retinal Vein Occlusion, Inflammation | Altered Intercellular Communication | All three patients developed a branch retinal vein occlusion at the site of inflammation. | 21691257 |
| Intraocular inflammation, Inflammation, Choroiditis, Communicable Diseases, Retinitis, Vitritis, Retinal Vasculitis, Systemic disease | Altered Intercellular Communication | These patients had no other evidence of intraocular inflammation, including vitritis, retinitis, retinal vasculitis, or choroiditis, nor was there any systemic disorder associated with inflammation, infection, or coagulation identified. | 21691257 |
| Inflammation, Primary malignant neoplasm | Altered Intercellular Communication | IDO expression in LL-SCC may aid immune escape and chronic inflammation to promote cancer progression. | 21692032 |
| Inflammation, Fatigue | Altered Intercellular Communication | The associations of adiposity, physical activity and inflammation with fatigue in older adults. | 21693185 |
| Alveolar Septum, Interstitial inflammation | Altered Intercellular Communication | Routine examination of a lung biopsy, 4 months after transplantation, showed nonspecific, diffuse interstitial inflammation with alveolar septal fibrosis. | 21693291 |
| Inflammation, Atrophic | Altered Intercellular Communication | Ghrelin is a hormone produced in the oxyntic glands of the stomach, and under conditions of chronic inflammation and atrophy, serum ghrelin concentrations decrease. | 21693726 |
| Inflammation, Atrophic | Altered Intercellular Communication | Ghrelin is a hormone produced in the oxyntic glands of the stomach, and under conditions of chronic inflammation and atrophy, serum ghrelin concentrations decrease. | 21693726 |
| Inflammation, TSC22D3 gene, Neoplasms | Altered Intercellular Communication | Glucocorticoid-induced TNFR family-related Receptor (GITR)-mediated inflammation of tumor infiltrating leucocytes (TILs) in the tumor microenvironment might play a role during the multistep carcinogenetic process as either tumor promoting factor according to an inflammatory microenvironment or as a feature of anti-tumor activity. | 21694467 |
| Inflammation, Microorganism | Altered Intercellular Communication | We reviewed the clinical findings, therapeutic interventions, and visual outcomes of patients with suppurative scleral inflammation without preceding microbial keratitis who had microorganisms isolated from scleral scrapings. | 21694595 |
| Inflammation, Scleritis, Scedosporium, Pseudomonas aeruginosa | Altered Intercellular Communication | Of 349 patients with scleritis diagnosed from 1999 to 2009, 6 adults (1.7%) presented with suppurative inflammation of the anterior sclera due to Pseudomonas aeruginosa (2), Streptococcus pneumoniae (2), Staphylococcus aureus (1), and Scedosporium apiospermum/Pseudallescheria boydii (1). | 21694595 |
| Inflammation, S100A4 protein, human | Altered Intercellular Communication | Looking for a potential biomarker of malignant transformation in the setting of chronic inflammation we studied the levels of prostaglandin E2 (PGE(2)), as well as peptide growth factors [epidermal growth factor (EGF) and transforming growth factor a (TGFa)], harbingers of injury and repair, in gastric juice aspirated at endoscopy from patients with CAG, CAG/IM, AdCa, and controls. | 21695403 |
| Inflammation, Progranulins, Frontotemporal Lobar Degeneration | Altered Intercellular Communication | FTLD has recently been shown to be associated with mutations in GRN gene, coding for progranulin, a multifunctional secreted glycoprotein involved in cell cycle, inflammation and tissue repair. | 21695656 |
| Inflammation, Dyslipidemias | Altered Intercellular Communication | Brain volume reductions have also been associated with chronic low-grade inflammation and dyslipidaemia. | 21695767 |
| Inflammation, Dyslipidemias | Altered Intercellular Communication | This study investigated the relationships among T2DM, gender, inflammation, dyslipidaemia, and hippocampal volumes. | 21695767 |
| Inflammation, Anemia, Sickle Cell, Amyloidosis | Altered Intercellular Communication | After elimination of other causes, it was concluded that amyloidosis was the result of recurrent acute inflammation secondary to sickle cell disease. | 21695882 |
| Inflammation, Cyclophosphamide/Vincristine/Dacarbazine Regimen, Cardiovascular Diseases | Altered Intercellular Communication | sCD40L was higher in smokers and negatively associated with lung function and positively associated with total cholesterol and markers of inflammation, but not with other established cardiovascular disease (CVD) risk factors. | 21696538 |
| Inflammation, Diabetes Mellitus, Insulin-Dependent, Albuminuria, Endothelial dysfunction | Altered Intercellular Communication | YKL-40 is involved in inflammation and endothelial dysfunction, and is increased in patients with type 1 diabetes, with an independent association between increasing YKL-40 levels and increasing levels of albuminuria. | 21696606 |
| Traumatic injury | Altered Intercellular Communication | The prior trauma to the nail also suggests that posttraumatic inflammation may play a role in SUM development. | 21696688 |
| Narcolepsy, daytime sleepiness, Cataplexy, Disease | Altered Intercellular Communication | Narcolepsy with cataplexy (NC) is a disabling disorder characterized by excessive daytime sleepiness and abnormal rapid eye movement (REM) sleep manifestations, due to a deficient hypocretin/orexin neurotransmission. | 21697009 |
| Inflammatory abnormality of the eye | Altered Intercellular Communication | Treatment with topical antiglaucoma medications for longer than 1 year may start to induce ocular surface inflammation. | 21697136 |
| Tears body substance, Glaucoma, Primary Open Angle | Altered Intercellular Communication | Proteomic profiling of inflammatory signaling molecules in the tears of patients on chronic glaucoma medication. | 21697136 |
| Inflammation, Atherosclerosis | Altered Intercellular Communication | Furthermore, our data suggest an intimate connection between atherosclerosis and the innate immune system and inflammation via TLR signaling in lower risk individuals. | 21698167 |
| Inflammatory Bowel Diseases, Inflammation | Altered Intercellular Communication | Decreased levels of this protease correlate with the severity of the inflammation in patients with inflammatory bowel disease. | 21698174 |
| Refractory Cytopenia of Childhood, Aggressive course, Epithelioid hemangioendothelioma, Renal Cell Carcinoma Pathway | Altered Intercellular Communication | Epithelioid angiosarcomas (EAS) of kidney are rare and aggressive tumors with noncharacteristic imaging features that overlap with those of inflammatory conditions and renal cell carcinoma (RCC). | 21698784 |
| Diabetes Mellitus, Non-Insulin-Dependent, Inflammation, Kidney Failure, Chronic Kidney Diseases | Altered Intercellular Communication | Chronic kidney disease (CKD) associated with type 2 diabetes is the leading cause of kidney failure, with both inflammation and oxidative stress contributing to disease progression. | 21699484 |
| Inflammation, Kidney Diseases, Retinal Diseases, Neuropathy | Altered Intercellular Communication | PAD; SMI; ED; 24-hour blood pressure Holter; lipid profile; insulin resistance; testosterone; chronic inflammation; nephropathy; retinopathy; neuropathy. | 21699670 |
| Autoimmune Diseases, Inflammation, Kabardian language | Altered Intercellular Communication | We conclude that autoimmunity and inflammation may be involved in the pathogenesis of KBD, in particular in the advanced stage. | 21699943 |
| Mediastinal lymphadenopathy, Granuloma, Myocarditis | Altered Intercellular Communication | Mediastinal adenopathy with mid-myocardial scar and/or focal myocardial inflammation was observed in 14 patients; lymph nodes revealed noncaseating granulomas in all. | 21700089 |
| SLC5A6 gene, Myocarditis | Altered Intercellular Communication | Decrease in SMVT correlated with resolution of myocardial inflammation on serial (18)FDG PET-CTs. | 21700089 |
| ARCN1 gene, Inflammation, Chronic Obstructive Airway Disease | Altered Intercellular Communication | Eosinophilic inflammation in chronic obstructive pulmonary disease (COPD) is predictive for responses to inhaled steroids. | 21700610 |
| Airway structure, ARCN1 gene | Altered Intercellular Communication | This suggests that breath analysis may be used for assessment and monitoring of airway inflammation in COPD. | 21700610 |
| vascular inflammations | Altered Intercellular Communication | In multivariate regression models adjusting for confounding variables, age remained independently associated with a composite Z score for systemic but not vascular inflammation (b=0.250, P<0.001, and b=0.276, P<0.001, for whites and African Americans, respectively). | 21700927 |
| Inflammation, Septic Shock | Altered Intercellular Communication | Glucocorticoids serve as important therapeutic agents in diseases of inflammation, but clinical use, especially in advanced septic shock, remains controversial because of the unpredictable response. | 21701417 |
| Upper Respiratory Infections | Altered Intercellular Communication | All patients had a mild clinical course and their respiratory capacity was stable between the second and third measurement, suggesting that the duration of respiratory inflammation was two months. | 21702977 |
| Respiratory Distress Syndrome, Adult, Inflammation | Altered Intercellular Communication | However, it remains unknown how alveolar IL-8 is related to pulmonary and systemic inflammation in patients predisposed for ARDS. | 21703617 |
| Inflammation, Pulmonary Complication, Traumatic injury | Altered Intercellular Communication | The enhanced alveolar and systemic inflammation associated with alveolar IL-8 release should be considered to identify high-risk patients for pulmonary complications after multiple trauma to adjust surgical and other treatment strategies to the individual risk profile. | 21703617 |
| Inflammation, Inflammatory disorder | Altered Intercellular Communication | LPAs are known to be key mediators in inflammation, and several lines of evidence suggest a role for LPAs in inflammatory periodontal diseases. | 21703797 |
| Inflammatory disease of mucous membrane | Altered Intercellular Communication | Histopathologic examination of the resected appendix showed not only acute mucosal inflammation but also chronic inflammatory changes. | 21703964 |
| Inflammation, Heart failure, Anemia | Altered Intercellular Communication | Iron deficiency in community-dwelling US adults with self-reported heart failure in the National Health and Nutrition Examination Survey III: prevalence and associations with anemia and inflammation. | 21705484 |
| Inflammation, Carcinogenesis | Altered Intercellular Communication | Inflammation plays an important role in lung carcinogenesis. | 21706174 |
| Inflammation, Fever, CTCAE | Altered Intercellular Communication | Recurrent 38 degrees C fever and inflammation were cured by clindamycin of 1.2 g/day. | 21706849 |
| Bronchitis | Altered Intercellular Communication | Bariatric surgery significantly reduces the intake of inhaled corticosteroids and the levels of exhaled nitric oxide, thus bronchial inflammation, in asthmatics. | 21707447 |
| Glaucoma, Primary Open Angle, Inflammation | Altered Intercellular Communication | Morphological and biochemical analyses of the TM of POAG patients revealed loss of cells, increased accumulation of extracellular matrix (ECM), changes in the cytoskeleton, cellular senescence and the process of subclinical inflammation. | 21707516 |
| Pain Distress Question, Conjunctivitis | Altered Intercellular Communication | Pain and conjunctival inflammation resolved in 11 patients (91.67%) and improved from severe to mild in the remaining patient. | 21708086 |
| Pain Distress Question, Inflammatory abnormality of the eye, Bulla | Altered Intercellular Communication | ASP combined with AMT is safe and effective, alleviates pain and discomfort, reduces ocular inflammation, and promotes epithelial healing and resolution of bullae in patients with BK with poor visual potential. | 21708086 |
| Inflammation | Altered Intercellular Communication | Measurements of joint thickening and joint inflammation were performed with Grey-scale and semi-quantitative Power-Doppler US (PDUS). | 21708444 |
| Pneumonitis | Altered Intercellular Communication | In Rag2(-/-)gc(-/-) immunodeficient mice reconstituted with human peripheral mononuclear cells (huPBMCs), PAM reduces disease severity and mortality caused by human seasonal H1N1 and avian H5N1 influenza virus, and controls the lung inflammation and viral replication. | 21708931 |
| Degenerative polyarthritis, Inflammation | Altered Intercellular Communication | Perfluorooctanoate (PFOA) and perfluorooctane sulfonate (PFOS) are persistent environmental contaminants that affect metabolic regulation, inflammation, and other factors implicated in the pathogenesis of osteoarthritis (OA). | 21709135 |
| Inflammation, "Alzheimers Disease", Data types - Address | Altered Intercellular Communication | Both inflammation and oxidative injury are features of Alzheimer's disease (AD), but the contribution of these intertwined phenomena to the loss of working memory in this disease is unclear. | 21709376 |
| Gingiva, Inflammatory disease of mucous membrane | Altered Intercellular Communication | At the beginning, bad dental and periodontal conditions with gingival signs and recurrent mucosal inflammation were found in all patients. | 21709654 |
| Inflammatory Bowel Diseases, Crohn Disease, Ulcerative Colitis | Altered Intercellular Communication | Inflammatory bowel diseases (IBD) include ulcerative colitis (UC) and Crohn's disease (CD), which are chronic inflammatory conditions affecting the gastrointestinal tract. | 21710330 |
| Inflammation, Head and neck structure, Malignant Neoplasms | Altered Intercellular Communication | Six cases were combined with local inflammation on head and neck and 2 cases were combined with malignant tumor. | 21710715 |
| Inflammation, Chronic purulent otitis media, Pain Distress Question | Altered Intercellular Communication | Chronic suppurative otitis media (CSOM) is frequently associated with symptoms of inflammation like discharge from the ear or pain. | 21711571 |
| Pruritus, Eczema | Altered Intercellular Communication | Nummular eczema is a chronic inflammatory condition characterized by pruritus and histologically characterized by spongiosis. | 21712693 |
| Inflammation, Primary malignant neoplasm, Unintentional weight loss | Altered Intercellular Communication | Utility of routine hematological and inflammation parameters for the diagnosis of cancer in involuntary weight loss. | 21712730 |
| Cessation of life, Inflammation, Primary malignant neoplasm, Anemia | Altered Intercellular Communication | Inflammation and anemia are associated with cancer, and recent studies showed that red blood cell distribution width (RDW) is a predictor of mortality, including cancer-related death. | 21712730 |
| Inflammation, Primary malignant neoplasm | Altered Intercellular Communication | In patients with IWL, the hematological and inflammation parameters were statistically different in patients with cancer and in those without cancer. | 21712730 |
| Communicable Diseases, Thrombosis, Arteritis, Atherosclerosis | Altered Intercellular Communication | The chronic infection status suffered by HIV-infected individuals promotes chronic arterial inflammation and injury, which leads to dysfunction of the endothelium, atherosclerosis and thrombosis. | 21713302 |
| Inflammation, Thrombosis | Altered Intercellular Communication | Circulating microparticles (MPs) are involved in thrombosis, inflammation, and angiogenesis. | 21713319 |
| Inflammation, Degenerative disorder | Altered Intercellular Communication | Recent studies have shown that renin-angiotensin system overactivation is involved in the aging process in several tissues as well as in longevity and aging-related degenerative diseases by increasing oxidative damage and inflammation. | 21713375 |
| Inflammation, Dyslipidemias | Altered Intercellular Communication | Mixed dyslipidemia, oxidative stress and inflammation are related to a high risk for cardiovascular events. | 21714585 |
| Refractory anemias, Inflammation | Altered Intercellular Communication | YKL-40 concentrations are elevated in the serum of patients with RA compared to healthy subjects, and YKL-40 has been suggested to be an auto-antigen and may play a role in development of RA and in inflammation. | 21714862 |
| Acute Kidney Injury, CTCAE, Inflammation, Malnutrition, Kidney Failure, Acute | Altered Intercellular Communication | Animal and human studies suggest that inflammation and malnutrition are common in acute kidney injury (AKI) patients. | 21714897 |
| Inflammation, Kidney Failure, Acute | Altered Intercellular Communication | However, only a few studies reported CRP, a marker of inflammation, albumin, prealbumin and cholesterol, markers of nutritional status were associated with the prognosis of AKI patients. | 21714897 |
| Inflammation, Malnutrition, Kidney Failure, Acute | Altered Intercellular Communication | Inflammation and malnutrition were common in patients with AKI. | 21714897 |
| Degenerative polyarthritis, Inflammation, Tumor necrosis, Knee pain | Altered Intercellular Communication | One of the sources of knee pain in osteoarthritis (OA) is believed to be related to local chronic inflammation of the knee joints, which involves the production of inflammatory cytokines such as tumor necrosis factor alpha (TNFa), interleukin (IL)-6, and nerve growth factor (NGF) in the synovial membrane, and these cytokines are believed to promote pathological OA. | 21714933 |
| Folliculitis, Blepharitis, Rosacea, Ear Inflammation, Alopecia, CTCAE, Disease | Altered Intercellular Communication | Their role in human diseases is under investigation, and a growing number of studies indicated that they contribute to chronic inflammatory conditions of the skin, such as rosacea, blepharitis, otitis externa, alopecia and folliculitis. | 21715284 |
| Inflammation, Depression, CTCAE | Altered Intercellular Communication | Association between depression and inflammation--differences by race and sex: the META-Health study. | 21715300 |
| Inflammation, Depression, CTCAE | Altered Intercellular Communication | To test whether the association between depression and inflammation differs by race and sex. | 21715300 |
| Inflammation, Bipolar Disorder | Altered Intercellular Communication | Although depressive symptoms are associated with inflammation, the association varies by race and sex. | 21715300 |
| Inflammation | Altered Intercellular Communication | Chronic inflammation of the lamina propria was present in 9 cases, and focal neutrophil infiltration was identified in 3 cases. | 21716082 |
| Inflammation, Vasculitis of large artery | Altered Intercellular Communication | Antigen-antibody (IgA) complexes activate the alternative complement pathway, resulting in inflammation and small vessels vasculitis. | 21717040 |
| Influenza due to Influenza A virus subtype H1N1, Inflammation | Altered Intercellular Communication | In contrast to several reports so far, CT findings of H1N1 virus infection in patients with mild illness are variable, including suggestive findings of inflammation involving large and/or small airways. | 21717297 |
| Pain Distress Question, Inflammation | Altered Intercellular Communication | To assess the efficacy of sclerosant Polidocanol in foam form compared to liquid form and to determine safety profile by monitoring the complications (Pain, inflammation and pigmentation). | 21717876 |
| Pain Distress Question, Hyperpigmentation, Inflammation | Altered Intercellular Communication | However Pain, inflammation, and hyperpigmentation appeared more often with foam Polidocanol therapy. | 21717876 |
| Granulomatous inflammation, Hyperplasia | Altered Intercellular Communication | Histopathological examination of the skin biopsy revealed epidermal hyperplasia and granulomatous inflammation in the dermis, with budding yeast. | 21719337 |
| vascular inflammations, Pathologic Processes | Altered Intercellular Communication | BD is a rare, chronic multi-systemic vasculitis and interaction of activated platelets with leucocytes has been linked to pathological disorders associated with vascular inflammation. | 21719422 |
| Waldenstrom Macroglobulinemia, Fibrosis Assessment, Phlebitis | Altered Intercellular Communication | The lesion of ISD is characterised by lymphoplasmacytic inflammation, fibrosis, phlebitis and increased numbers of IgG4-positive plasma cells. | 21719489 |
| Inflammation | Altered Intercellular Communication | In neither apparently healthy nor the entire population was inflammation associated with airflow limitation in central airways. | 21719491 |
| Inflammation, Smoking | Altered Intercellular Communication | Smoking is related to an impaired D(L,CO) in association with an increase in systemic inflammation. | 21719491 |
| Inflammation | Altered Intercellular Communication | The object was surrounded by a low-density area, suggesting severe inflammation. | 21720094 |
| Inflammation | Altered Intercellular Communication | Severe inflammation of the right renal vein was observed. | 21720094 |
| Inflammation | Altered Intercellular Communication | At surgery, the gallbladder wall was observed to be extremely thick because of severe inflammation, and cholecystectomy was performed. | 21720095 |
| Inflammation, Hypoxia | Altered Intercellular Communication | Immunologically restricted patients exhibit a pronounced inflammation and inadequate response to hypoxia in fracture hematomas. | 21720875 |
| Inflammation, HIV Infections | Altered Intercellular Communication | Increased plasma levels of extracellular mitochondrial DNA during HIV infection: a new role for mitochondrial damage-associated molecular patterns during inflammation. | 21722755 |
| Inflammation | Altered Intercellular Communication | The relationship of serum PON-1 activity with SAA during low-grade chronic inflammation is unclear. | 21722818 |
| Inflammation, Electrocardiogram: left ventricle hypertrophy (finding), SLC22A5 gene | Altered Intercellular Communication | CAE is common in SCD and is associated with left ventricular hypertrophy and inflammation. | 21722914 |
| Celiac Disease, Inflammation, Malignant neoplasm of gastrointestinal tract | Altered Intercellular Communication | Low risk of gastrointestinal cancer among patients with celiac disease, inflammation, or latent celiac disease. | 21723236 |
| Celiac Disease, Inflammation, Malignant neoplasm of gastrointestinal tract | Altered Intercellular Communication | Of patients with celiac disease, 372 developed incident GI cancers; 347 patients with inflammation and 38 with latent celiac disease developed GI cancers. | 21723236 |
| Celiac Disease, Inflammation, Malignant neoplasm of gastrointestinal tract | Altered Intercellular Communication | In the first year after diagnosis and initial biopsy, celiac disease was associated with 5.95-fold increase in risk of incident GI cancer (95% confidence interval [CI], 4.64-7.64); the hazard ratio [HR] for inflammation was 9.13 (95% CI, 7.19-11.6) and for latent celiac disease was 8.10 (95% CI, 4.69-14.0). | 21723236 |
| Celiac Disease, Inflammation, Malignant neoplasm of gastrointestinal tract | Altered Intercellular Communication | After the first year, patients were at no significant increase in risk for GI cancers; the HR for celiac disease was 1.07 (95% CI, 0.93-1.23), for inflammation it was 1.16 (95% CI, 0.98-1.37), and for latent celiac disease it was 0.96 (95% CI, 0.56-1.66). | 21723236 |
| Celiac Disease, Inflammation, Malignant neoplasm of gastrointestinal tract | Altered Intercellular Communication | Although celiac disease, inflammation, and latent disease all increase risk for GI cancers in the first year after diagnosis, there is no increase in risk thereafter. | 21723236 |
| Communicable Diseases, Inflammation, Granulation finding, Necrosis | Altered Intercellular Communication | The wound severity scores, which vary with the severity of infection and inflammation, necrotic and granulation tissues, and wound depth and area, were assessed weekly for 9 weeks. | 21723750 |
| Inflammation, Necrosis | Altered Intercellular Communication | Subgroup analyses comparing the WF10 and placebo groups showed statistically significant decreases of infection and inflammation (0.0 +- 0.0 versus 0.8 +- 0.9, respectively, p < .01), necrotic tissue (0.0 +- 0.0 versus 0.8 +- 1.1, respectively, p < .01), and an increase of the amount of granulation tissue (0.1 +- 0.3 versus 0.8 +- 1.2, respectively, p < .05). | 21723750 |
| Communicable Diseases, Inflammation, Necrosis | Altered Intercellular Communication | We concluded that the addition of WF10 to standard wound care statistically significantly reduced the wound severity score, infection and inflammation, and necrotic tissue and enhanced the formation of granulation tissue. | 21723750 |
| Inflammation | Altered Intercellular Communication | CyPA may represent a novel and specific marker for cardiac inflammation. | 21724278 |
| Primary malignant neoplasm | Altered Intercellular Communication | A comparison of inflammation-based prognostic scores in patients with cancer. | 21724383 |
| Primary malignant neoplasm | Altered Intercellular Communication | Components of the systemic inflammatory response, combined to form inflammation-based prognostic scores (modified Glasgow Prognostic Score (mGPS), Neutrophil Lymphocyte Ratio (NLR), Platelet Lymphocyte Ratio (PLR), Prognostic Index (PI), Prognostic Nutritional Index (PNI)) have been associated with cancer specific survival. | 21724383 |
| Primary malignant neoplasm, Neoplasms | Altered Intercellular Communication | The results of the present study show that systemic inflammation-based scores, in particular the mGPS and PI, have prognostic value in cancer independent of tumour site. | 21724383 |
| Abnormal gastrointestinal motility, Inflammation, Stasis | Altered Intercellular Communication | Clinical course is benign and etiology unclear, but it has been associated to chronic inflammation due to fecal stasis and abnormal colonic motility. | 21724496 |
| Inflammation, Carcinogenesis, Neoplasms | Altered Intercellular Communication | Vitamin D and calcium affect several pathways involved in inflammation, tumor growth, and immune surveillance relevant to carcinogenesis. | 21724580 |
| Atrial Fibrillation, Inflammation, Atrial Fibrillation by ECG Finding | Altered Intercellular Communication | Atrial fibrillation (AF) is associated not only with inflammation but also with structural remodelling and altered endothelial activation which may contribute to clot formation, embolization and mortality. | 21725858 |
| Kidney Failure, Chronic, Inflammation | Altered Intercellular Communication | Hemodialysis (HD)-induced inflammation has a pathogenetic role in patients with end-stage renal disease (ESRD). | 21725917 |
| Inflammation | Altered Intercellular Communication | Role of the hemodialysis vascular access type in inflammation status and monocyte activation. | 21725929 |
| Inflammation, Congestion | Altered Intercellular Communication | Monotherapy of imiquimod is less effective than the two other regimens in decreasing parasite load, inflammation and congestion at the inoculated site. | 21726098 |
| Inflammation, Atherosclerosis | Altered Intercellular Communication | Peroxisome proliferator-activated receptor-g (PPARg) is involved in regulation of macrophage inflammation and in atherosclerosis. | 21726861 |
| Inflammation, Coronary heart disease, Choline Dehydrogenase, Mitochondrial | Altered Intercellular Communication | Inflammation is a risk factor for coronary heart disease (CHD). | 21726863 |
| Inflammation, Data types - Address | Altered Intercellular Communication | The involvement of ADAM8 and -15 together with inflammation consisting of B-cells may indicate active remodelling of the aortic wall leading to AD. | 21728902 |
| Inflammation, Fever, CTCAE | Altered Intercellular Communication | It also significantly reduced inflammation frequency and shortened high fever duration. | 21729572 |
| Airway structure, Asthma, Allergy - Charge Type Reason | Altered Intercellular Communication | Effect of urbanisation on asthma, allergy and airways inflammation in a developing country setting. | 21730351 |
| Asthma | Altered Intercellular Communication | Peri-urban adolescents had more asthma, atopy and airways inflammation and were exposed to more indoor pollution. | 21730351 |
| Acute hepatitis | Altered Intercellular Communication | Interleukin-8 (IL-8, CXCL8) is a potent chemoattractant for neutrophils and contributes to acute liver inflammation. | 21731723 |
| Hepatic inflammation, Lymphoproliferative Disorder of the Skin | Altered Intercellular Communication | IL-8 is strongly activated in CLD, thus likely contributing to hepatic inflammation. | 21731723 |
| Chorioretinitis, Inflammation, Toxoplasmosis, Panuveitis | Altered Intercellular Communication | In toxoplasmosis patients, positive RT-PCR results were statistically correlated with the chorioretinitis area (more than three disc areas; p = 0.002), with the age older than 50 (p = 0.0034) and with a clinical anterior inflammation (Tyndall >=1/2+) and panuveitis; (p = 0.0001). | 21732111 |
| Intraocular inflammation | Altered Intercellular Communication | For the diagnosis of viral or toxoplasmosis-associated intraocular inflammation, the usefulness of laboratory diagnosis tools (RT-PCR and GWC) depends on parameters other than the sensitivity of the tests. | 21732111 |
| Inflammation, Atherosclerotic lesion | Altered Intercellular Communication | The vulnerable atherosclerotic lesion exhibits the proliferation of neovessels and inflammation. | 21732164 |
| Inflammation, Liver Cirrhosis | Altered Intercellular Communication | The disease can progress from an asymptomatic inflammation to a cirrhosis. | 21732301 |
| Inflammatory abnormality of the eye, Visual blurring, Influenza | Altered Intercellular Communication | The authors recommend alertness for visual blurring and ocular inflammation after influenza A infection. | 21732577 |
| Schizophrenia, Parkinsonian Disorders | Altered Intercellular Communication | D-serine (DSR) allosterically modulates in-vivo NMDAR-mediated neurotransmission and has been shown to improve negative and antipsychotic drug-induced parkinsonian symptoms in schizophrenia patients. | 21733283 |
| Inflammation, Metabolic Syndrome X | Altered Intercellular Communication | Inflammation is a hallmark of the metabolic syndrome, which also contributes to a pro-atherogenic state. | 21733322 |
| vascular inflammations, atherosclerotic | Altered Intercellular Communication | Carotid [(18)F]-FDG uptake, an index of vascular inflammation within the atherosclerotic plaques, was measured as standardized uptake value (SUV). | 21733518 |
| vascular inflammations, International Medical Terminology, Atherosclerosis | Altered Intercellular Communication | The present study reveals that serum level of PEDF is independently associated with vascular inflammation and IMT, thus suggesting that PEDF level is a novel biomarker that could reflect atherosclerosis in humans. | 21733518 |
| Inflammation, Fever, CTCAE, Arthritis, Infectious | Altered Intercellular Communication | Fever and signs of inflammation were more frequent and synovial fluid cell counts were higher in patients with improbable septic arthritis. | 21733734 |
| Diabetic Nephropathy, Inflammation | Altered Intercellular Communication | Endogenous erythropoietin and the association with inflammation and mortality in diabetic chronic kidney disease. | 21734083 |
| Inflammation, Anemia, Chronic Kidney Diseases, diabetic | Altered Intercellular Communication | Anemia and inflammation are prevalent in diabetic patients with chronic kidney disease (CKD). | 21734083 |
| Inflammation, Chronic Kidney Diseases, diabetic | Altered Intercellular Communication | In diabetic patients with CKD, elevated endogenous EPO levels were predictive for mortality and were related mainly to markers of inflammation, independent of kidney function, and despite low hemoglobin levels. | 21734083 |
| Inflammation, Inflammatory disorder | Altered Intercellular Communication | EBC may be useful in measuring inflammation in several inflammatory lung diseases. | 21734340 |
| Inflammation, Primary malignant neoplasm, Neoplasm Metastasis | Altered Intercellular Communication | Hydrogen peroxide fuels aging, inflammation, cancer metabolism and metastasis: the seed and soil also needs "fertilizer". | 21734470 |
| Inflammation, Primary malignant neoplasm, Neoplasms | Altered Intercellular Communication | In this regard, a series of recent studies have elegantly shown that the production of hydrogen peroxide, by both cancer cells and cancer-associated fibroblasts, may provide the necessary "fertilizer," by driving accelerated aging, DNA damage, inflammation and cancer metabolism, in the tumor microenvironment. | 21734470 |
| Alzheimers Disease | Altered Intercellular Communication | The superior colliculus and retina obtained from late-stage Alzheimer's disease revealed upregulated amyloidogenic and inflammatory signaling along the anteroposterior axis of the retinal-primary visual cortex pathway. | 21734608 |
| allergic inflammation | Altered Intercellular Communication | We believe that Aspergillus clusters may have been present in this patient for several years, and the pathological findings might be manifested as an asymptomatic localized allergic inflammation. | 21735744 |
| Vitreous inflammatory cells | Altered Intercellular Communication | Sudden severe anterior chamber and vitreous inflammation occurred beginning on the day following surgery, but it disappeared spontaneously without complications. | 21735756 |
| Inflammation | Altered Intercellular Communication | Macrophage accumulation enhances chronic inflammation in adipose tissue, but macrophage phenotypic change in human epicardial adipose tissue and its role in atherogenesis are unknown. | 21737014 |
| Gustatory rhinitis, Rhinitis | Altered Intercellular Communication | Other causes of rhinitis: mixed rhinitis, rhinitis medicamentosa, hormonal rhinitis, rhinitis of the elderly, and gustatory rhinitis. | 21737037 |
| Rhinitis, Acromegaly, Gustatory rhinitis, Drug Eruptions, Rhinitis, Atrophic, Common Cold, IL13 gene, Occupational | Altered Intercellular Communication | It is important to consider a comprehensive differential of possible rhinitis types when considering the diagnosis of chronic rhinitis, including at least 9 subtypes of nonallergic rhinitis: drug-induced rhinitis, gustatory rhinitis, hormonal-induced rhinitis, infectious rhinitis, nonallergic rhinitis with eosinophilia syndrome, occupational rhinitis, senile rhinitis, atrophic rhinitis, and nonallergic rhinopathy. | 21737037 |
| Inflammation, Thrombosis | Altered Intercellular Communication | Patients with severe protein C deficiency had lower arterial blood pressure (P = .0006), greater serum creatinine concentration (P < .0001), elevated markers of thrombosis and inflammation, and impairment of fibrinolysis (P < .0001). | 21737232 |
| Inflammation, Obesity | Altered Intercellular Communication | Impaired lung function has been linked to obesity and systemic inflammation. | 21737489 |
| Communicable Diseases, Inflammation, Traumatic injury | Altered Intercellular Communication | Progressive inflammation of the arachnoid mater due to trauma, infection, or hydrocortisone was reported as early as the 1970s. | 21738091 |
| Inflammation, Neoplasms | Altered Intercellular Communication | The low expression of membranous b-catenin was associated with a high degree of tumor infiltration (p = 0.02), high amount of inflammation (p = 0.01), and high degree of poor tumor differentiation (p < 0.001). | 21739269 |
| Sebaceous Adenocarcinoma, Inflammation, Neoplasms | Altered Intercellular Communication | These changes were associated with poor tumor differentiation and an increase in the tumor infiltration and inflammation, pointing at a potential role of a low E-cadherin and low b-catenin expression for poor prognosis of sebaceous eyelid adenocarcinomas. | 21739269 |
| Inflammation | Altered Intercellular Communication | Low levels of IGF-1 in RA synovial fluid were associated with systemic inflammation and inversely related to the levels of resistin. | 21739426 |
| Rupture, Angina, Unstable | Altered Intercellular Communication | Inflammation within vulnerable coronary plaques may cause unstable angina by promoting rupture and erosion. | 21740772 |
| Inflammation, Fever, CTCAE, Lymphadenopathy | Altered Intercellular Communication | [Diagnostic value of lymphadenopathy associated with fever and inflammation of unknown origin: a study of 69 patients]. | 21741135 |
| Inflammation, Fever, CTCAE | Altered Intercellular Communication | The diagnosis of fever or inflammation of unknown origin (FUO/IUO) is guided by the search of clinical clues. | 21741135 |
| Inflammation | Altered Intercellular Communication | In general, genes associated with inflammation (such as RANKL and CD68) were overexpressed in symptomatic compared with asymptomatic plaques. | 21741279 |
| Supranuclear paralysis, Inflammation | Altered Intercellular Communication | Although little is known about the etiology of progressive supranuclear palsy (PSP), genetic and epigenetic factors, oxidative injury and inflammation are thought to contribute to its development and/or progression. | 21741294 |
| APP gene, Inflammation, Aortic Aneurysm, Abdominal | Altered Intercellular Communication | Abdominal aortic aneurysms (AAA) are associated with inflammation, apoptosis, and matrix degradation. | 21741794 |
| Pterygium Of Conjunctiva And Cornea | Altered Intercellular Communication | Postoperative conjunctival inflammation after pterygium surgery with amniotic membrane transplantation versus conjunctival autograft. | 21742306 |
| Pterygium Of Conjunctiva And Cornea, Conjunctivitis | Altered Intercellular Communication | Main outcome measures included presence of host conjunctival inflammation around the surgical site at 1 month after surgery and also recurrence of pterygium. | 21742306 |
| Conjunctivitis | Altered Intercellular Communication | At 1 month after surgery, different grades of host conjunctival inflammation were present in 16 eyes (84.2%) in the AMT group and in 3 eyes (15%) in the conjunctival autograft group (P = .02). | 21742306 |
| Pterygium Of Conjunctiva And Cornea, Conjunctivitis | Altered Intercellular Communication | After pterygium surgery, conjunctival inflammation was significantly more common with AMT than with conjunctival autograft. | 21742306 |
| Inflammation, Giant Cell Arteritis, Atheroma | Altered Intercellular Communication | [Peripheral arterial involvement in giant cell arteritis: how to differentiate between atheroma and inflammation?]. | 21742449 |
| Refractory anemias, Rheumatoid Arthritis, destruction joint, Inflammation | Altered Intercellular Communication | In rheumatoid arthritis (RA), a complex cytokine network drives chronic inflammation and joint destruction. | 21742639 |
| Refractory anemias, Rheumatoid Arthritis, Inflammation | Altered Intercellular Communication | To analyse the expression of SIRT1 in synovial tissues and cells of patients with rheumatoid arthritis (RA) and to study the function of SIRT1 in inflammation and apoptosis in RA. | 21742641 |
| Inflammation | Altered Intercellular Communication | The TNFa-induced overexpression of SIRT1 in RA synovial cells contributes to chronic inflammation by promoting proinflammatory cytokine production and inhibiting apoptosis. | 21742641 |
| Inflammation | Altered Intercellular Communication | The reduction in CFH amount or its complement-modulating activity may lead to inadequate control of complement-driven inflammation at the outer retina. | 21743006 |
| Inflammation | Altered Intercellular Communication | These results suggest a new perspective of the interaction between oxidative stress and inflammation, and provide a potential novel treatment strategy for age-related macular degeneration. | 21743006 |
| Behavioral Symptoms, Data types - Address | Altered Intercellular Communication | An imbalance of different neurotransmitters--glutamate, acetylcholine, dopamine, and serotonin--has been proposed as the neurobiological basis of behavioral symptoms in AD. | 21743130 |
| Granulomatous inflammation, Crohn Disease | Altered Intercellular Communication | Bilateral dacryocystorhinostomies were performed through an external approach and revealed multiple nodular masses in both lacrimal sacs, which on biopsy, contained granulomatous inflammation consistent with extraintestinal Crohn disease. | 21743368 |
| Nasolacrimal Duct Obstruction, Crohn Disease, Granulomatous inflammation | Altered Intercellular Communication | A literature search from 1966 to the present using the PubMed database revealed three previous publications describing nasolacrimal duct obstruction associated with Crohn disease, but these cases did not show pathologic evidence of granulomatous inflammation. | 21743368 |
| Crohn Disease, Granulomatous inflammation | Altered Intercellular Communication | To our knowledge, this is the first reported case of extraintestinal Crohn disease with granulomatous inflammation affecting the lacrimal-outflow system. | 21743368 |
| Abnormality of levator veli palatini muscle, Fibrosis Assessment, Inflammation, Atrophic | Altered Intercellular Communication | Histopathologic specimens revealed abnormal levator muscle fibers with various degrees of atrophy, fibrosis, and regeneration without inflammation. | 21743372 |
| Eosinophilic inflammation | Altered Intercellular Communication | Nasal lavage CCL24 levels correlate with eosinophils trafficking and symptoms in chronic sino-nasal eosinophilic inflammation. | 21743872 |
| Airway structure, Sleep Apnea, Obstructive | Altered Intercellular Communication | Obstructive sleep apnea syndrome (OSAS) has been shown to be associated to upper and lower airways inflammation. | 21743883 |
| Airway structure, Sleep Apnea, Obstructive | Altered Intercellular Communication | In 13 non-smoking subjects affected by untreated OSAS and in 11 non-smoking normal volunteers, airway inflammation was detected by analyses of the induced sputum. | 21743883 |
| Sleep Apnea, Obstructive, Nasal inflammation | Altered Intercellular Communication | In addition, in 12 subjects of the OSAS group, nasal inflammation was detected by the analysis of induced nasal secretions at baseline, and after 1, 10 and 60 days of CPAP treatment. | 21743883 |
| Inflammation, Biliary Tract Cancer | Altered Intercellular Communication | Medical history and the risk of biliary tract cancers in Shanghai, China: implications for a role of inflammation. | 21744094 |
| Inflammation, Biliary Tract Cancer | Altered Intercellular Communication | Several lines of evidence suggest that inflammation may play a role in the etiology of biliary tract cancers. | 21744094 |
| Biliary Tract Cancer | Altered Intercellular Communication | We used logistic regression to estimate odds ratios (ORs) and 95% confidence intervals (CIs) for biliary tract cancers in relation to six inflammation-related conditions. | 21744094 |
| Inflammation, Biliary Tract Cancer | Altered Intercellular Communication | Although the mechanisms are unclear, our results further support the role for inflammation in the etiology of biliary tract cancers. | 21744094 |
| Inflammation, Calcification of coronary artery, Autoimmune Diseases, Myocardial Reperfusion, Lupus Erythematosus | Altered Intercellular Communication | Influence of chronic inflammation and autoimmunity on coronary calcifications and myocardial perfusion defects in systemic lupus erythematosus patients. | 21744266 |
| Inflammation, Calcification of coronary artery, Coronary Artery Disease, Lupus Erythematosus, Systemic | Altered Intercellular Communication | Conventional risk factors for coronary artery disease as well as markers of an ongoing inflammation did not show any association with perfusion defects and/or coronary artery calcifications in SLE patients. | 21744266 |
| Inflammation, Restenosis | Altered Intercellular Communication | The peptide from C-terminal domain of MCP-1 (Ingramon) has been shown to inhibit monocyte migration and possess anti-inflammatory activity in animal models of inflammation and post-angioplasty restenosis. | 21744268 |
| Hepatic inflammation | Altered Intercellular Communication | Variability at the IL28B locus is associated with HBV viral load and hepatic inflammation. | 21745278 |
| Hepatitis | Altered Intercellular Communication | Genetic variation of IL28B may prevent HBV progression by reducing viral load and liver inflammation, providing a valuable gene therapy tool. | 21745278 |
| Hepatitis | Altered Intercellular Communication | The correlation between liver histology and serum markers of liver inflammation was analysed. | 21745311 |
| Inflammation, Fibrosis Assessment | Altered Intercellular Communication | On the basis of multivariate analysis, the AST and apolipoprotein A1 levels and stage of fibrosis were highly predictive of significant inflammation. | 21745311 |
| Inflammation, "Alzheimers Disease", Diabetes Mellitus, Non-Insulin-Dependent | Altered Intercellular Communication | These include chronic low-grade inflammation (inflammageing), a major risk factor for ageing and age-related diseases, such as Alzheimer's disease and type II diabetes. | 21745717 |
| Inflammation, "Alzheimers Disease", Diabetes Mellitus, Non-Insulin-Dependent | Altered Intercellular Communication | These include chronic low-grade inflammation (inflammageing), a major risk factor for ageing and age-related diseases, such as Alzheimer's disease and type II diabetes. | 21745717 |
| Inflammation, Fibrosis Assessment, Waldenstrom Macroglobulinemia | Altered Intercellular Communication | Multifocal fibrosclerosis(MFS) is a rare disorder of unknown etiology, characterized by chronic inflammation with dense fibrosis and lymphoplasmacytic infiltration into the connective tissue of various organs. | 21747150 |
| Inflammation | Altered Intercellular Communication | The RA synovial compartment contains several ligands for CCR1, CCR2, and CCR5 as well as other chemokines and receptors involved in monocyte recruitment to the site of inflammation. | 21747955 |
| Pain Distress Question, Irritation, Inflammation | Altered Intercellular Communication | Yet up to one-third of patients complain of post-surgical pain due to irritation and inflammation caused by the mesh and the fixation materials. | 21748483 |
| Inflammation, Hemorrhage, Pain, Postoperative | Altered Intercellular Communication | Because excessive bleeding can increase postoperative pain and inflammation, use of PRP also reportedly decreases the need for narcotics and increases speed of recovery after TKA. | 21748512 |
| palladium, Inflammation | Altered Intercellular Communication | PD and PSP subjects also had increases in microglia number and activation in the SN(pc) suggesting a link between inflammation and clinical disease. | 21748523 |
| Inflammation, Fibrosis Assessment, Fatty degeneration | Altered Intercellular Communication | Primary outcome revealed no significant difference between treatment groups in all histologic parameters (steatosis, P = 0.137; hepatocellular inflammation, P = 0.320; fibrosis, P = 0.229). | 21748770 |
| Inflammatory Hepatocellular Adenoma, Fatty degeneration, Fibrosis Assessment, Balloon Dilatation | Altered Intercellular Communication | Overall improvement in steatosis, hepatocellular inflammation, ballooning degeneration, and fibrosis was observed (P <= 0.001). | 21748770 |
| Structure of cavernous sinus, Inflammation, Sinus Thrombosis, Intracranial, Venous hypertension, Traumatic injury, Dural Arteriovenous Fistula | Altered Intercellular Communication | Although hormonal influences, inflammation, trauma, sinus thrombosis, venous hypertension, and congenital origin have been proposed as sources of dural arteriovenous fistulas (DAVFs) in cavernous and sigmoid sinuses, the etiology of these lesions remains controversial. | 21748936 |
| Inflammation, Viral meningitis | Altered Intercellular Communication | The viral meningitis most likely caused the inflammation, that may be responsible for the occurrence of the cavernous sinus DAVF. | 21748936 |
| Inflammation | Altered Intercellular Communication | Prompt treatment for inflammation may help to prevent the development of DAVFs. | 21748936 |
| Structure of cavernous sinus, Inflammation, Sinus Thrombosis, Intracranial, Venous hypertension, Traumatic injury, Dural Arteriovenous Fistula | Altered Intercellular Communication | Although hormonal influences, inflammation, trauma, sinus thrombosis, venous hypertension, and congenital origin have been proposed as sources of dural arteriovenous fistulas (DAVFs) in cavernous and sigmoid sinuses, the etiology of these lesions remains controversial. | 21748936 |
| Inflammation, Chronic disease | Altered Intercellular Communication | Inflammation is a common pathophysiological pathway for a number of chronic diseases, and is strongly influenced by sociodemographic factors and lifestyle. | 21749016 |
| Inflammation, Periodontitis, Metabolic Syndrome X, Atherosclerosis, ETV3 wt Allele | Altered Intercellular Communication | The systemic inflammation in both metabolic syndrome (MetS) and periodontitis is a common denominator of the association of these conditions with higher risk of atherosclerosis. | 21749167 |
| Trachoma , Tebi | Altered Intercellular Communication | A trachoma case was defined by the presence of Trachomatous inflammation-Follicular (TF) and/or Trachomatous inflammation-Intense (TI) in either eye. | 21749703 |
| Gastroesophageal reflux disease, Communicable Diseases, Gastro-esophageal reflux disease with esophagitis, Inflammatory disease of mucous membrane | Altered Intercellular Communication | To compare the characteristics of the traditional Chinese medicine (TCM) syndromes of gallbladder heat attacking the stomach and stagnant heat of the liver and stomach in patients with reflux esophagitis (RE), in terms of clinical symptoms, combination of gallbladder conditions, esophageal mucosal inflammation, gastric bile reflux under endoscopy and helicobacter pylori (HP) infection. | 21749823 |
| Gastroesophageal reflux disease, Communicable Diseases, Inflammatory disease of mucous membrane | Altered Intercellular Communication | The general data, characteristics of clinical symptoms, combination of gallbladder conditions, esophageal mucosal inflammation, gastric bile reflux under endoscopy and HP infection of the two patterns were compared. | 21749823 |
| Gastroesophageal reflux disease, Communicable Diseases, Inflammatory disease of mucous membrane | Altered Intercellular Communication | The extent of the esophageal mucosal inflammation under endoscopy as well as the gastric bile reflux and the incidence of HP infection was also more severe (P<0.01). | 21749823 |
| Inflammation, Diplopia, Fibrosis Assessment, Scleroderma , Enophthalmos | Altered Intercellular Communication | Inflammation and progressive collagen fibrosis involving subcutaneous tissue, fat, and muscle secondary to linear scleroderma may result in enophthalmos and diplopia. | 21750423 |
| Degenerative polyarthritis, Inflammation, Degenerative disorder of cartilage | Altered Intercellular Communication | Osteoarthritis (OA) is considered a complex illness, characterized by cartilage degeneration, secondary synovial membrane inflammation, and subchondral bone sclerosis. | 21750942 |
| Granuloma, Inflammation | Altered Intercellular Communication | Dalen-Fuchs nodules (DFN), granulomas, and non-granulomatous foci of inflammation were micro-dissected from 15 cases. | 21751146 |
| Conjunctivitis, Keratoconjunctivitis Sicca | Altered Intercellular Communication | After the treatment, above all else the clinical signs of conjunctival inflammation disappeared, but remained KCS symptoms, which were disappearing only slowly. | 21751740 |
| Pain Distress Question, Inflammatory abnormality of the eye | Altered Intercellular Communication | Once daily dosing of bromfenac ophthalmic solution 0.09% for postoperative ocular inflammation and pain. | 21751945 |
| Inflammatory abnormality of the eye | Altered Intercellular Communication | The primary efficacy endpoint was cleared summed ocular inflammation score (SOIS) by Day 15. | 21751945 |
| Inflammatory abnormality of the eye | Altered Intercellular Communication | The bromfenac 0.09% group was significantly higher compared to the placebo group in the primary endpoint of the proportion of subjects who had cleared ocular inflammation by Day 15 (P < 0.0001). | 21751945 |
| Cataract, Eye pain, Inflammatory abnormality of the eye | Altered Intercellular Communication | Bromfenac ophthalmic solution 0.09% dosed once daily is clinically safe and effective for the treatment of ocular inflammation and the reduction of ocular pain associated with cataract surgery. | 21751945 |
| Tissue damage, Inflammation | Altered Intercellular Communication | Cytokine expression is upregulated in chronic CD patients; therefore, the degree of inflammation and tissue damage in CD is dependent on the expression of specific cytokines within the tissue. | 21752952 |
| Delirium, "Alzheimers Disease", Inflammation, Data types - Address | Altered Intercellular Communication | In Alzheimer disease (AD), systemic inflammation is known to give rise to a delirium. | 21753171 |
| Delirium, Inflammation, Illness Behavior | Altered Intercellular Communication | However, systemic inflammation also gives rise to other centrally mediated symptoms in the absence of a delirium, a concept known as sickness behavior. | 21753171 |
| Inflammation, Tumor necrosis, Illness Behavior | Altered Intercellular Communication | Systemic inflammation is characterized by the systemic production of the proinflammatory cytokines tumor necrosis factor-a (TNFa) and interleukin-6 (IL-6) that mediate immune to brain communication and the development of sickness behavior. | 21753171 |
| Refractory anemias, Rheumatoid Arthritis, destruction joint, Inflammation | Altered Intercellular Communication | Matrix metalloproteinases (MMPs) are involved in joint destruction in rheumatoid arthritis (RA), and are strongly associated with levels of inflammation. | 21753786 |
| Inflammation, Weight decreased, Overweight | Altered Intercellular Communication | Weight loss combined with exercise may reduce inflammation and improve physical functioning in overweight, sedentary, older adults. | 21753869 |
| Pneumonitis | Altered Intercellular Communication | Significant variability in the severity and duration of ARDS-associated pulmonary inflammation could be linked to heterogeneity in the inflammatory capacity of neutrophils. | 21755013 |
| Inflammation | Altered Intercellular Communication | The excessive inflammation at the prosthesis-corneal junction and the unsuited height of the optical cylinder might have been the main reasons of STP. | 21756746 |
| Inflammation, Depressed mood | Altered Intercellular Communication | Depressed individuals not only suffer from chronic low grade inflammation, but also exhibit an inflammatory hyper-responsiveness to acute stress. | 21756997 |
| vascular inflammations | Altered Intercellular Communication | Effects of marine omega-3 fatty acids on serum systemic and vascular inflammation markers and oxidative stress in hemodialysis patients. | 21757893 |
| Inflammation, vascular inflammations, Cardiovascular Diseases | Altered Intercellular Communication | High concentrations of serum inflammation markers, especially vascular inflammation markers, are an important risk factor for cardiovascular diseases in hemodialysis patients. | 21757893 |
| HD Term Type, Inflammation, Cardiac dysfunction | Altered Intercellular Communication | Our study pointed out that BNP >1,200 pg/ml as a marker of cardiac dysfunction and CRP >= 10 mg/l as a marker of inflammation identify HD patients at increased risk of CV mortality. | 21757955 |
| Inflammation, Tooth Loss, Obesity | Altered Intercellular Communication | Total tooth loss and systemic correlates of inflammation: role of obesity. | 21760638 |
| Inflammation, Tooth Loss | Altered Intercellular Communication | In conclusion, subjects with total tooth loss, although devoid of periodontal inflammation, may exhibit increased levels of systemic inflammatory mediators. | 21760638 |
| Inflammation, Obesity | Altered Intercellular Communication | Possible implications are discussed with respect to obesity and its relationship to inflammation. | 21760638 |
| Inflammation, Musculoskeletal, Pain Distress Question | Altered Intercellular Communication | Despite these advances, in some patients inflammation is not diminished sufficiently to prevent irreversible musculoskeletal damage, thereby necessitating surgical intervention to reduce pain and improve function. | 21761229 |
| Inflammation, Prostate carcinoma, Benign prostatic hypertrophy, prostatitis | Altered Intercellular Communication | Testosterone and inflammation have been linked to the development of common age-associated diseases affecting the prostate gland including prostate cancer, prostatitis, and benign prostatic hypertrophy. | 21761342 |
| Prostate, prostatitis | Altered Intercellular Communication | These data demonstrate that tight junction architecture in the prostate is related to changes in serum testosterone levels, and identify an androgen-regulated mechanism that potentially contributes to the development of prostate inflammation and consequent pathology. | 21761342 |
| Inflammation, Hemorrhage, Dental Plaque | Altered Intercellular Communication | Examinations for gingival inflammation (MGI), bleeding and plaque were performed after 12 weeks. | 21762151 |
| Inflammation, Hemorrhage, Dental Plaque | Altered Intercellular Communication | Examinations for gingival inflammation (MGI), bleeding and plaque were performed after 6 and 12 weeks. | 21762150 |
| methyldopa, Inflammation | Altered Intercellular Communication | Inflammation, among many factors, has been suggested to play an important role in AMD pathogenesis. | 21762495 |
| methyldopa, Inflammation | Altered Intercellular Communication | The possible involvement of IL-22 and IL-17 in the inflammation that contributes to AMD may herald a new approach to treat AMD. | 21762495 |
| Capillaritis, Interstitial inflammation | Altered Intercellular Communication | Neutrophil predominant capillaritis and interstitial inflammation is an uncommon renal biopsy finding, with a broad differential diagnosis. | 21762649 |
| Capillaritis, Interstitial inflammation | Altered Intercellular Communication | Renal biopsy demonstrated prominent neutrophilic capillaritis with interstitial inflammation, and fibrinoid deposits in medullary capillaries and interstitium. | 21762649 |
| Inflammation, Metabolic Syndrome X, MS gene | Altered Intercellular Communication | We investigated an association between lipoprotein-associated phospholipase A(2) (Lp-PLA(2)) activity, inflammation, and oxidative stress in women with metabolic syndrome (MS). | 21762913 |
| Inflammation | Altered Intercellular Communication | This association was also affected by menopause status, suggesting that Lp-PLA(2) may represent a novel marker for oxidation and inflammation in MS. | 21762913 |
| Pain Distress Question, Inflammatory abnormality of the eye | Altered Intercellular Communication | Safety and efficacy of bromfenac ophthalmic solution (Bromday) dosed once daily for postoperative ocular inflammation and pain. | 21762992 |
| Inflammatory abnormality of the eye | Altered Intercellular Communication | The proportion of subjects who had cleared ocular inflammation by day 15 was significantly higher in the bromfenac 0.09% group than in the placebo group (P < 0.0001). | 21762992 |
| Cataract, Pain Distress Question, Inflammatory abnormality of the eye | Altered Intercellular Communication | Bromfenac 0.09% dosed once daily was clinically safe and effective for reducing and treating ocular inflammation and pain associated with cataract surgery. | 21762992 |
| Inflammation, Frailty, Chronic disease | Altered Intercellular Communication | Frailty is associated with a pro-inflammatory state, which has been characterized by elevated levels of systemic inflammatory biomarkers, but has not been related to the number of co-existing chronic diseases associated with inflammation. | 21763008 |
| Inflammation, Central heterochromia, Keratitis, Conjunctival hyperemia, Corneal edema | Altered Intercellular Communication | Age, gender, and diverse clinical and laboratory characteristics, including course and laterality of AU; prevalence of positive results for PCR, GWC, or both; conjunctival redness; corneal edema; history of keratitis; presence of keratic precipitates; synechiae; heterochromia; and grade of inflammation. | 21764137 |
| Herpes Simplex Infections, Inflammation, herpesvirus 3, human, Vitritis | Altered Intercellular Communication | Herpes simplex virus AU often had severe anterior chamber inflammation, whereas the presence of vitritis was more common in RV AU and VZV AU. | 21764137 |
| Inflammation, Cerebrovascular accident, Chronic Kidney Diseases, Vascular calcification | Altered Intercellular Communication | Furthermore, relevant serum markers of inflammation, vascular calcification, and vessel wall degradation might be an indication of stroke risk in CKD patients. | 21764239 |
| Inflammation | Altered Intercellular Communication | Serum measurements of cytokines, mediators of various B and T cell activities, are important markers of inflammation and immune dysregulation. | 21764327 |
| Inflammation, Atherosclerosis | Altered Intercellular Communication | Among 221 genes involved in angiogenesis, inflammation and atherosclerosis, 24 were shown to be differentially modulated locally, by analysis with custom-designed DNA array technology. | 21764664 |
| Diabetes Mellitus, Non-Insulin-Dependent, Chronic Kidney Diseases, Cardiovascular Diseases | Altered Intercellular Communication | Predictive role of multilocus genetic polymorphisms in cardiovascular disease and inflammation-related genes on chronic kidney disease in Type 2 diabetes--an 8-year prospective cohort analysis of 1163 patients. | 21765051 |
| Inflammation, Kidney Diseases, Chronic Kidney Diseases | Altered Intercellular Communication | Seventy-seven single-nucleotide polymorphisms (SNPs) of 54 candidate genes for cardiorenal diseases and inflammation were genotyped in 1163 patients with no past history of CKD at baseline. | 21765051 |
| Inflammation, Diabetes Mellitus, Non-Insulin-Dependent, Chronic Kidney Diseases | Altered Intercellular Communication | Risk associations with PON1, PON2, CETP, ITGA2 and LTA genetic polymorphisms underline the importance of lipid metabolism, haemostasis and inflammation in the development of CKD in patients with Type 2 diabetes. | 21765051 |
| Degenerative polyarthritis, Arthritis | Altered Intercellular Communication | Microarray analysis of the infrapatellar fat pad in knee osteoarthritis: relationship with joint inflammation. | 21765106 |
| Degenerative polyarthritis, Inflammation | Altered Intercellular Communication | To examine differences in genes involved in fat metabolism, energy homeostasis, adipogenesis, and inflammation between endstage and early-stage knee osteoarthritis (OA) infrapatellar fat pads (IFP). | 21765106 |
| Sepsis, Inflammation | Altered Intercellular Communication | However, systemic inflammation associated with sepsis, a common AKI-trigger, may affect cystatin C. We studied the impact of sepsis on cystatin C levels in plasma. | 21765189 |
| Disease, Arthritis, Pseudogout | Altered Intercellular Communication | The acute form of the disorder is referred as pseudogout, which can cause a severe joint inflammation. | 21765235 |
| Sepsis, Inflammation, Hypotension, CTCAE | Altered Intercellular Communication | Recently, kynurenine has been identified as an endothelium-derived relaxing factor produced during inflammation, raising the possibility that this novel pathway may contribute to hypotension in human sepsis. | 21765346 |
| Inflammatory Bowel Diseases, Inflammation | Altered Intercellular Communication | The absence of this pattern in subjects with inflammatory bowel disease suggests it is not a sequel of inflammation or oxidative stress. | 21766334 |
| Inflammation, Anemia, Malignant Neoplasms | Altered Intercellular Communication | In 84 patients with advanced solid malignant tumors, but without iron or vitamin B12 and folate deficiency anemia, we measured serum pHp levels and common markers of iron status, erythropoiesis and inflammation. | 21766512 |
| Inflammation, Nia (fungus) | Altered Intercellular Communication | Lesions were classified into two groups based on the need for surgery and surgical findings: positive inflammation activity (PIA) and negative inflammation activity (NIA). | 21767926 |
| Parkinson Disease, palladium | Altered Intercellular Communication | Alpha-synuclein accumulation in intracellular inclusions, oxidative stress and microglia-mediated inflammation in the substantia nigra are crucial events in the pathogenesis of Parkinson's disease (PD). | 21767974 |
| Inflammation, Idiopathic osteoarthritis | Altered Intercellular Communication | We compared inflammation in the knee after total knee replacement (TKR) for primary osteoarthritis between two groups of patients undergoing joint replacement with and without synovectomy. | 21768630 |
| Inflammation, physiopathological, Diabetes Mellitus | Altered Intercellular Communication | HDL dysfunction associated with low-grade inflammation is a co-determinant of pre-diabetic states and their progression to diabetes. | 21769500 |
| Inflammation, Malignant Pleural Mesothelioma, Neoplasms | Altered Intercellular Communication | Chronic inflammation in tumor stroma is an independent predictor of prolonged survival in epithelioid malignant pleural mesothelioma patients. | 21769693 |
| Inflammation | Altered Intercellular Communication | In multivariate analysis, chronic inflammation in stroma was an independent predictor of survival (HR = 0.659, 95% CI 0.464-0.937, P = 0.02). | 21769693 |
| Inflammation, Atherosclerosis | Altered Intercellular Communication | Our study demonstrated that total WBC counts play an important role in inflammation and are associated with the presence, severity and extent of coronary atherosclerosis detected by MSCT. | 21769817 |
| Inflammation, Corneal edema | Altered Intercellular Communication | Although inflammation became quiescent within a month, corneal edema developed 4 months after insertion. | 21770807 |
| Inflammation | Altered Intercellular Communication | These results did not provide conclusive support for a hypothesis of a pathophysiological role of inflammation intracranially. | 21771198 |
| Inflammation, Postcholecystectomy Syndrome, Stenosis | Altered Intercellular Communication | Inadequate calculi removal, bile stasis, inflammation and strictures are causes of postcholecystectomy biliary syndrome. | 21771404 |
| Neurotransmitters, Depression, CTCAE | Altered Intercellular Communication | Testing homocysteine-induced neurotransmitter deficiency, and depression of mood hypothesis in clinical practice. | 21771745 |
| Neurotransmitters, Depression, CTCAE | Altered Intercellular Communication | high total plasma homocysteine (tHcy) levels may cause neurotransmitter deficiency, and consequently depression of mood. | 21771745 |
| Takotsubo Cardiomyopathy, Myocardial, Myocarditis, physiopathological | Altered Intercellular Communication | Stress cardiomyopathy was accurately identified by CMR using specific criteria: a typical pattern of LV dysfunction, myocardial edema, absence of significant necrosis/fibrosis, and markers for myocardial inflammation. | 21771988 |
| Virus Diseases, Hepatitis | Altered Intercellular Communication | The purpose of this study was to elucidate whether the expression of Foxp3 relates not to the viral infection but to the resulting liver inflammation. | 21772667 |
| Hepatitis | Altered Intercellular Communication | Our findings indicate that, independently of the initial inducer, liver inflammation is correlated with elevated expression of apoptosis mediators and is followed by local Treg accumulation. | 21772667 |
| Hepatosplenomegaly, Histiocytosis haematophagic, Lymphohistiocytosis, Hemophagocytic, Fever, CTCAE, Cytopenia | Altered Intercellular Communication | Hemophagocytic syndrome (HS) is a severe hyper inflammatory condition whose cardinal symptoms are prolonged fever, cytopenia, hepatosplenomegaly, and hemophagocytosis by activated, morphologically benign macrophages. | 21773661 |
| Inflammation | Altered Intercellular Communication | We hypothesized that body mass may affect DNA methylation through increased estrogen and chronic inflammation. | 21775555 |
| Inflammation, SSB gene, Rheumatoid Factor, Hypergammaglobulinemia | Altered Intercellular Communication | The laboratory findings showed high inflammation markers, rheumatoid factor 128 IU, Waaler-Rose 256 IU, anti nuclear antibody (ANA) 1/640, SSA (anti Sjogren antigen A) and SSB (anti Sjogren antigen B) positive and hypergammaglobulinemia. | 21776446 |
| Inflammation, Cardiovascular Diseases, Cancer-related fatigue, Dyslipidemias, Chronic Kidney Diseases | Altered Intercellular Communication | Dyslipidemia, oxidative stress (OS) and inflammation increase the risk of cardiovascular disease in chronic renal failure (CRF) patients. | 21776461 |
| Inflammation, Psoriasis, Cardiovascular Diseases | Altered Intercellular Communication | Psoriasis confers an independent risk of cardiovascular disease that is likely to be related to systemic inflammation. | 21777216 |
| Dermatomyositis, Inflammation, Dermatomyositis, Childhood Type, Gastrointestinal tract structure | Altered Intercellular Communication | Juvenile dermatomyositis (JDM) is an important subtype of dermatomyositis characterized by inflammation of muscle, skin and gastrointestinal tract. | 21777536 |
| Cell Death, Liver carcinoma, Inflammation, FAM126A gene | Altered Intercellular Communication | Development of hepatocellular carcinoma (HCC) is a complex and progressive disease that involves cycles of liver cell death, inflammation, and tissue regeneration/remodelling. | 21778049 |
| Airway structure, Wheezing | Altered Intercellular Communication | The functional outcome in preschool severe wheezers with eosinophilic airway inflammation and increased reticular basement membrane (RBM) thickness is unknown. | 21778162 |
| Inflammatory abnormality of the eye | Altered Intercellular Communication | Suppressor of cytokine signaling-1 (SOCS1) inhibits lymphocyte recruitment into the retina and protects SOCS1 transgenic rats and mice from ocular inflammation. | 21778271 |
| Inflammation, Fever, CTCAE, Empyema, Pleural | Altered Intercellular Communication | However, pyothorax developed, and in October, 2008 he was admitted again with fever and inflammation. | 21778636 |
| Low Back Pain, Inflammation | Altered Intercellular Communication | There was a rapid reduction of the left iliopsoas abscess, his inflammation and lumbago symptoms reduced, and he was discharged in January 2009. | 21778636 |
| Inflammation, Hypogonadism, Weight decreased, Osteopenia | Altered Intercellular Communication | Hypogonadism, weight loss, and chronic inflammation are other contributors to bone loss in a variety of disease states. | 21778745 |
| Inflammation, Nasal Polyps, Chronic sinusitis, Craniosynostosis | Altered Intercellular Communication | Additionally, eosinophilic chronic rhinosinusitis (ECRS) in Japan is considered to be a subgroup of CRS with nasal polyps (CRSwNP) characterized by eosinophil-dominant inflammation. | 21778815 |
| Tumor necrosis, Psoriasis | Altered Intercellular Communication | Tumor necrosis factor a antagonists are proven to be effective for the treatment of chronic inflammatory conditions, such as psoriasis. | 21778902 |
| Fibrosis Assessment, Hepatic inflammation, Fatty degeneration | Altered Intercellular Communication | Moreover, both ARFI and Fibroscan((r)) values increased in proportion to the severity of hepatic inflammation when fibrosis stage is low, but not in proportion to the severity of steatosis. | 21779759 |
| Chronic lymphocytic inflammation, Struma Ovarii | Altered Intercellular Communication | Authors report a case of a 52-year-old woman after struma ovarii with chronic lymphocytic inflammation excision. | 21780949 |
| Chronic lymphocytic inflammation | Altered Intercellular Communication | In histopatholgical examination struma ovarii with chronic lymphocytic inflammation was diagnosed. | 21780949 |
| Hashimoto Disease, Chronic lymphocytic inflammation, Struma Ovarii | Altered Intercellular Communication | In this case, an early diagnosis of Hashimoto disease resulted from excision of struma ovarii with chronic lymphocytic inflammation. | 21780949 |
| Inflammation, Anemia, idarubicin, Chronic disease | Altered Intercellular Communication | This audit reviewed red cell transfusion practice, degree of anaemia, iron deficiency anaemia (IDA) and chronic disease or anaemia of inflammation (AI) in cardiothoracic and orthopaedic surgical patients who had available iron studies. | 21781124 |
| Inflammation, Primary malignant neoplasm, Carcinoma, S100A4 protein, human | Altered Intercellular Communication | The presence of inflammatory reaction in peri-tumoural connective tissue is generally considered as a defense mechanism against cancer, but inflammation tissue in malignant transformation and early steps of oncogenesis has been recently proven to play a supporting and aggravating role in some carcinomas. | 21781456 |
| Atrial Fibrillation, Inflammation, Atrial Fibrillation by ECG Finding | Altered Intercellular Communication | Currently, precise mechanisms of atrial fibrillation (AF) are uncertain but proved to be associated with inflammation. | 21782262 |
| Chronic inflammation | Altered Intercellular Communication | Further, there was an increase of immature collagen in the connective tissue, and signs of a mild chronic inflammation. | 21783002 |
| Inflammation, Dryness (characteristic) | Altered Intercellular Communication | Chronic inflammation, dryness of the gingiva, or even the minimal glycogen accumulation in the fibroblasts may have played a role. | 21783002 |
| Dystrophic calcification, Tonsillitis | Altered Intercellular Communication | Tonsilloliths are rare dystrophic calcifications caused by chronic inflammation of the tonsils. | 21783100 |
| vascular inflammations, Encephalomyelitis, Acute Disseminated | Altered Intercellular Communication | In this case, LCL is considered to be associated with ADEM, an acute autoimmune response to myelin, and vascular inflammation of the gray matter of the spinal cord. | 21783334 |
| Cerebral Amyloid Angiopathy, Inflammation, Hemorrhage, Vasculitis | Altered Intercellular Communication | The third VE case was associated with numerous microhemorrhages in keeping with cerebral amyloid angiopathy-related inflammation or Ab-related angiitis. | 21784350 |
| Allergic asthma, Inflammation, AHR wt Allele | Altered Intercellular Communication | Accordingly, we hypothesized that local aerosol delivery of GSNO could ameliorate AHR and inflammation in the ovalbumin-sensitized and -challenged (OVA) mouse model of allergic asthma. | 21784966 |
| Allergic asthma, Airway structure | Altered Intercellular Communication | In conclusion, in the OVA mouse model of allergic asthma, aerosolized GSNO has rapid and sustained antibronchoconstrictive effects but does not substantially alter airway inflammation. | 21784966 |
| airway disease, Inflammation, Asthma | Altered Intercellular Communication | Systemic inflammation is now recognised as an important part of some airway diseases, but the involvement of systemic inflammation in the pathogenesis of airway inflammatory phenotypes of asthma remains unknown. | 21785157 |
| Airway structure | Altered Intercellular Communication | Plasma elastase was significantly increased in people with neutrophilic airway inflammation. | 21785157 |
| Inflammation, Venous Thromboembolism, Heart failure, Malignant Neoplasms, Kidney Failure, Liver Cirrhosis, Acute infectious disease | Altered Intercellular Communication | Patients with acute infection, renal failure, heart failure, liver cirrhosis, chronic inflammation, venous thromboemboli, malignancies and pregnancy were excluded. | 21785169 |
| Inflammation, Juvenile polyposis syndrome | Altered Intercellular Communication | However, because CRP is a marker for systemic inflammation, this test is not specific to PJI. | 21786056 |
| Refractory anemias, Inflammation | Altered Intercellular Communication | The impact on the clinical situation and the RA severity regarding the inflammation was analyzed. | 21786121 |
| Renal Insufficiency, Acute inflammation, Nephritic syndrome, Impaired | Altered Intercellular Communication | Carriers of Pro allele more often have signs of active glomerular inflammation and vascular impairment with renal dysfunction while carriers of Arg/Arg genotype more frequently demonstrate isolated nephritic syndrome. | 21786572 |
| Tissue damage, Inflammation, Cyclophosphamide/Vincristine/Dacarbazine Regimen, Cardiovascular Diseases | Altered Intercellular Communication | C-reactive protein (CRP) is a sensitive, non-specific systemic marker for inflammation and tissue damage in the human body and independently associated with incident cardiovascular disease (CVD) and traditional CVD risk factors. | 21788019 |
| Postherpetic neuralgia, Inflammation, Herpes zoster disease | Altered Intercellular Communication | Intraocular pressure, inflammation, steroid use, surgical procedures, anterior segment complications, post-herpetic neuralgia, and delayed herpes zoster pseudodendrites. | 21788078 |
| Inflammation, Keratitis, Keratopathy, Exacerbation of cGVHD | Altered Intercellular Communication | Younger patients had more episodes of delayed pseudodendritiform keratitis and flares of inflammation compared with older patients, who had more problems related to neurotrophic keratopathy. | 21788078 |
| Tumor necrosis, Inflammation | Altered Intercellular Communication | Etanercept blocks tumour necrosis factor (TNF)-a, which plays a central role in the psoriatic inflammation process. | 21790728 |
| Psoriasis | Altered Intercellular Communication | A combination of selected inflammatory factors (which we term the Index of Psoriasis Inflammation) in combination with PASI might reflect inflammatory status in psoriasis more accurately than each one separately. | 21790728 |
| Gastritis | Altered Intercellular Communication | According to endoscopic diagnosis, patients with gastric cardiac inflammation and BE were selected from March 2008 to February 2009 in Renji Hospital, Shanghai Jiaotong University School of Medicine. | 21791021 |
| Inflammation, Esophagitis | Altered Intercellular Communication | Inflammation in the gastric antrum was more severe in the CIM group (45.1% vs 26.6%), in contrast, esophagitis was more severe in the BE group (53.1% vs 35.4%). | 21791021 |
| Inflammation, Metabolic Diseases, Fibrosis Assessment | Altered Intercellular Communication | Adiponectin protects from inflammation and fibrosis in metabolic liver disease. | 21791204 |
| Inflammation, Fibrosis Assessment, Steatohepatitis | Altered Intercellular Communication | The current data indicate that in NASH hepatic inflammation and fibrosis but not hepatic steatosis induce liver MMP-9 activity, and this induction seems to be related to the anti-inflammatory activity of adiponectin rather than its effect on hepatocellular MMP-9 expression. | 21791204 |
| Inflammation, Lymphocytic infiltration, Ulcer | Altered Intercellular Communication | Gastroscopy revealed an ulcer with a suspicious malignant appearance, and histology of the endoscopic specimen showed severe chronic inflammation and lymphocytic infiltration. | 21791308 |
| Stable chronic Graft vs Host Disease, Inflammation, Fibrosis Assessment, Functional Disability | Altered Intercellular Communication | The sclerotic skin manifestations of cGVHD (ScGVHD) result from inflammation and fibrosis of the dermis, subcutaneous tissue, or fascia, leading to significant functional disability. | 21791415 |
| Granulomatous inflammation | Altered Intercellular Communication | The Surepath smear showed crowded cellular groups with abundant epithelioid histiocytes and lymphocytes consistent with granulomatous inflammation. | 21791908 |
| Granulomatous inflammation, Sarcoidosis | Altered Intercellular Communication | Uterine cervical sarcoidosis, although rare, can be an overlooked cause of non-necrotizing granulomatous inflammation in a cervical Pap test. | 21791908 |
| Sarcoidosis, Tuberculosis | Altered Intercellular Communication | Sarcoidosis should be a diagnosis of exclusion; other common conditions with similar morphologic presentation such as non-necrotizing tuberculosis, foreign body-related granulomatous inflammation, and neoplastic/chemotherapy-related sarcomatoid reaction need to be excluded in conjunction with the patient's clinical history. | 21791908 |
| vascular inflammations | Altered Intercellular Communication | AC13, a candidate biomarker for MPA, may be useful for monitoring disease activity and may exacerbate vascular inflammation through up-regulation of proinflammatory cytokines. | 21792834 |
| Inflammation | Altered Intercellular Communication | We report the case of a 2-week-old male who presented with a swollen, erythematous left index finger and elevated serum markers of inflammation. | 21792839 |
| Inflammation, Structure of posterior cerebral artery | Altered Intercellular Communication | These null findings might be due to methodological issues; however, it is unlikely that strong and long-lasting associations between inflammation and PCa risk were missed as this was a large database with long follow-up. | 21792885 |
| Inflammation, Colorectal Carcinoma | Altered Intercellular Communication | Toll-like receptors (TLRs) are mediators of inflammation in the gut and potentially important modulators of colon and rectal cancer risk. | 21792899 |
| Inflammation, Swelling | Altered Intercellular Communication | In patients without a history of inflammation, aggressive massage of the swelling could produce abundant intraoral salivary flow. | 21792955 |
| Airway structure, Signs and Symptoms, Respiratory, Asthma, Pneumonia | Altered Intercellular Communication | Whether respiratory symptoms, lung function, and airway inflammation differ in asthmatic patients with and without a history of pneumonia remains controversial. | 21793780 |
| Inflammation | Altered Intercellular Communication | We found no differences among groups in metabolic and hormonal profile, serum antioxidant capacity, or inflammation (P > 0.05). | 21795022 |
| Inflammation | Altered Intercellular Communication | We found no differences among groups in metabolic and hormonal profile, serum antioxidant capacity, or inflammation (P > 0.05). | 21795022 |
| Inflammation, Brain Neoplasms | Altered Intercellular Communication | We predicted that T. gondii could increase the risk of brain cancer because it is a long-lived parasite that encysts in the brain, where it provokes inflammation and inhibits apoptosis. | 21795265 |
| Osteomyelitis, Inflammation, Cellulitis | Altered Intercellular Communication | From a total of 23 lesions, we observed 10 sites of osteomyelitis, 10 sites of cellulitis, and 3 sites of aseptic inflammation confirmed by MRI, clinical presentation, histopathologic examination, and follow-up evaluation as a gold standard. | 21795373 |
| Osteomyelitis, Inflammation, Cellulitis | Altered Intercellular Communication | There was no significant difference between the semiquantitative indices of 5-h and 24-h (99m)Tc-IgG scanning for inflammation, cellulitis, and osteomyelitis. | 21795373 |
| Inflammation, Acanthosis, Fibrosis Assessment | Altered Intercellular Communication | The histological scoring system showed a significant reduction of inflammation, no difference in fibrosis, and an increase of acanthosis. | 21795984 |
| Intestinal metaplasia, Helicobacter pylori, Chronic inflammation, Atrophic | Altered Intercellular Communication | All of the cases were evaluated according to the Sydney classification, and the relation of Helicobacter pylori with chronic inflammation, atrophy, intestinal metaplasia, and activity was investigated by two pathologists. | 21796546 |
| Intestinal metaplasia, Inflammation, Helicobacter pylori | Altered Intercellular Communication | Activity, inflammation and intestinal metaplasia were found in 10 (10%), 70 (70%) and 10 (10%) of Helicobacter pylori (-) patients, respectively, and the numbers increased with increasing Helicobacter pylori intensity when compared with Helicobacter pylori (+) patients (p<0.01, p<0.01 and p<0.05, respectively). | 21796546 |
| Intestinal metaplasia, Inflammation, Atrophic | Altered Intercellular Communication | There was no significant difference between corpus alone or antrum alone Helicobacter pylori (+) and both corpus/antrum (+) patients in regards to the presence of activity, inflammation, intestinal metaplasia, and atrophy (p>0.05). | 21796546 |
| Intestinal metaplasia, Inflammation, Dyspepsia | Altered Intercellular Communication | As activity, inflammation and intestinal metaplasia increase with increasing Helicobacter pylori intensity in dyspepsia patients, Helicobacter pylori eradication treatment can be recommended in these patients. | 21796546 |
| Inflammation, Cardiovascular Diseases | Altered Intercellular Communication | Shiftwork is associated with an increased risk of cardiovascular diseases, but the possible role of inflammation in this relationship is not well known. | 21797781 |
| Inflammation, Cardiovascular Diseases | Altered Intercellular Communication | Our results suggest that 2- and 3-shift work is associated with increased systemic inflammation and the relationship is relatively independent of the considered risk factors of cardiovascular disease. | 21797781 |
| Inflammation, Pericardial Effusion, CTCAE, Fever, CTCAE, Pleuritic pain, Pleural Effusion, CTCAE | Altered Intercellular Communication | Specific symptoms, signs, or features were pleuritic chest pain (55.6%), fever (53.7%), elevated markers of inflammation (74.1%), pericardial effusion (88.9%), and pleural effusion (92.6%). | 21798503 |
| Inflammation, Psychotic Disorders | Altered Intercellular Communication | Inflammation in psychotic disorders: a population-based study. | 21798602 |
| Inflammation, Primary malignant neoplasm | Altered Intercellular Communication | The expression of cyclooxygenase 2 (COX-2) is usually increased in inflammation and cancer. | 21798652 |
| Inflammation | Altered Intercellular Communication | However, there is virtually no data about the link between glucagon and inflammatory parameters in obesity-related chronic low-grade inflammation. | 21798957 |
| Inflammation | Altered Intercellular Communication | This suggests that glucagon may be behind the association between inflammatory and metabolic parameters in obesity-associated chronic low-grade inflammation. | 21798957 |
| Inflammation | Altered Intercellular Communication | Adrenomedullin (ADM) plays an important role in inflammation and is a marker of future cardiovascular events. | 21798961 |
| Inflammation, Cerebrovascular accident | Altered Intercellular Communication | Immune responses to brain antigens occur after stroke, and experimental studies show that the likelihood of developing a detrimental autoimmune response to these antigens is increased by systemic inflammation at the time of stroke. | 21799171 |
| Inflammation, Critical Illness | Altered Intercellular Communication | These results indicate that PAB may not be a sensitive marker for evaluating the adequacy of nutrition support in critically ill patients with inflammation. | 21799187 |
| Conjunctivitis | Altered Intercellular Communication | Patients with EOD were younger and had more severe conjunctival inflammation (76% of inflamed eyes) than the EstD group, who had poorer VA (26.7%=VA<3/60, P<0.01) and more advanced disease. | 21799523 |
| Epithelial Damage, Colitis | Altered Intercellular Communication | On the one hand, age-related telomere shortening and inflamm-ageing may lead to the development of colonic inflammation, which results in epithelial damage. | 21799643 |
| Epithelial Damage, Colitis | Altered Intercellular Communication | On the one hand, age-related telomere shortening and inflamm-ageing may lead to the development of colonic inflammation, which results in epithelial damage. | 21799643 |
| Vascular Diseases, Inflammation, Aortic Aneurysm, Abdominal, Behavioral and psychological symptoms of dementia, APP gene | Altered Intercellular Communication | Lower limb athero-thrombosis and abdominal aortic aneurysm (AAA) have both been previously associated with neuropsychiatric symptoms possibly due to associated intracerebral vascular disease or systemic inflammation, hence suggesting that these illnesses may be regarded as models to investigate the vascular genesis of neuropsychiatric symptoms. | 21799922 |
| Esophagitis | Altered Intercellular Communication | If patients have evidence of esophageal inflammation, they undergo esophagogastroduodenoscopy (EGD). | 21800159 |
| Esophagitis | Altered Intercellular Communication | For computed tomography (CT) scans, esophageal inflammation was scored from 0 to 2. | 21800159 |
| Esophagitis | Altered Intercellular Communication | The kappa score for the inter-rater agreement of esophageal inflammation on EGD was 0.4584 (moderate). | 21800159 |
| Esophagitis | Altered Intercellular Communication | There was no agreement between immediate imaging and the endoscopic findings of esophageal inflammation after AFA. | 21800159 |
| Inflammation | Altered Intercellular Communication | His blood test showed slightly elevated muscle enzyme activity, and magnetic resonance imaging suggested severe inflammation of the muscles. | 21800697 |
| Inflammation, Asthma | Altered Intercellular Communication | Systemic inflammation is suggested as a mechanism by which overweight might induce asthma. | 21801245 |
| Inflammation, Asthma, Overweight | Altered Intercellular Communication | However, few studies have linked childhood overweight, inflammation and asthma. | 21801245 |
| Airway structure, Sleep Apnea, Obstructive, Osage language | Altered Intercellular Communication | Upper airway inflammation and narrowing are characteristics of obstructive sleep apnoea (OSA). | 21801324 |
| Eruptions, Inflammation, Contusions | Altered Intercellular Communication | Postoperatively, severe contusion, inflammation, and erythematous vesicular eruption resulted in a lengthened hospital stay. | 21801935 |
| Inflammation, Aneurysm | Altered Intercellular Communication | Periaortic inflammation and aneurysms in the nonfistula group completely disappeared in 10 of the 15 patients (67%). | 21802238 |
| ARCN1 gene, Inflammation, Exacerbation | Altered Intercellular Communication | Sputum inflammation predicts exacerbations after cessation of inhaled corticosteroids in COPD. | 21802933 |
| Low Vision, Pain Distress Question, Chronic inflammation, Photophobia, Corneal Neovascularization | Altered Intercellular Communication | All 7 patients presented with severe loss of vision, photophobia, pain, chronic inflammation, and corneal vascularization and scarring. | 21803325 |
| Pain Distress Question, Photophobia, Inflammation | Altered Intercellular Communication | For 30 +- 19.8 months, pain and photophobia were resolved in all 7 eyes; 6 eyes exhibited a stable epithelium with regressed corneal vascularization and reduced chronic inflammation. | 21803325 |
| Cataract, Inflammation, Central heterochromia | Altered Intercellular Communication | Anterior segment manifestations included low-grade inflammation, posterior synechiae, reversible hyperchromic heterochromia, and a mature cataract with "leopard spots." | 21803538 |
| Inflammation | Altered Intercellular Communication | An orbital computed tomographic scan showed inflammation of the left orbital, preseptal, and retroseptal spaces. | 21803720 |
| Rheumatoid Arthritis, Inflammation | Altered Intercellular Communication | Rheumatoid arthritis near remission: clinical rather than laboratory inflammation is associated with radiographic progression. | 21803751 |
| Inflammation, Damage | Altered Intercellular Communication | In general, both contribute to the progression of joint damage, but the relevance of residual inflammation in patients near remission is unclear. | 21803751 |
| Inflammation, Malnutrition | Altered Intercellular Communication | Lower micronutrient intakes were associated with malnutrition and inflammation. | 21804135 |
| Inflammation, Diabetes Mellitus, Atherosclerosis | Altered Intercellular Communication | Standard serum markers of inflammation, diabetes, renal function, ankle-brachial indexes and traditional risk factors for atherosclerosis were noted and Fontaine classification was applied for the severity of symptoms. | 21804488 |
| Acute Coronary Syndrome | Altered Intercellular Communication | The altered expression of inflammation-related microRNAs with microRNA-155 expression correlates with Th17 differentiation in patients with acute coronary syndrome. | 21804579 |
| GDC AJCC Clinical Stage Terminology | Altered Intercellular Communication | In conclusion, our study revealed the expression patterns of inflammation-related miRNAs in patients with ACS and found that miR-155 may be associated with Th17 cell differentiation. | 21804579 |
| Inflammation, Fibrosis Assessment | Altered Intercellular Communication | Using the METAVIR score, advanced disease was defined as fibrosis stage >=F2, and active inflammation as grade >=A2. | 21805422 |
| Inflammation, Fibrosis Assessment | Altered Intercellular Communication | Markers useful for fibrosis prediction also predicted marked inflammation. | 21805422 |
| Myelofibrosis, Inflammation, Chronic myeloproliferative disorder, Primary Myelofibrosis, PMF Regimen, Thrombocytosis, Polycythemia Vera | Altered Intercellular Communication | Myeloproliferation, myeloaccumulation (decreased apoptosis), inflammation, bone marrow fibrosis and angiogenesis are cardinal features of the Philadelphia-negative chronic myeloproliferative neoplasms: essential thrombocythemia (ET), polycythemia vera (PV) and primary myelofibrosis (PMF). | 21806350 |
| Inflammation | Altered Intercellular Communication | The mechanism of the apparent increased inflammation with this combination remains under investigation. | 21806360 |
| Inflammation, Idiopathic chronic inflammatory bowel disease, Ulcerative Colitis | Altered Intercellular Communication | There has been controversy over the significance of active inflammation of the terminal ileum (also known as backwash ileitis) in patients with ulcerative colitis (UC) and idiopathic inflammatory bowel disease of indeterminate type for diagnosis and pouch construction. | 21806956 |
| Inflammation | Altered Intercellular Communication | Data from patients with backwash ileitis (n = 132) were compared with those from 132 matched controls without ileal inflammation for age, sex, and type of proctocolectomies with ileal pouch construction (1- or 2-stage). | 21806956 |
| Inflammation, Idiopathic chronic inflammatory bowel disease, Ulcerative Colitis | Altered Intercellular Communication | Ileal inflammation is not a contraindication for restorative proctocolectomy with ileal pouch construction in patients with UC or idiopathic inflammatory bowel disease of indeterminate type. | 21806956 |
| Inflammation, pancolitis, Ulcerative Colitis, Colitis | Altered Intercellular Communication | Ileal inflammation with pancolitis is not a useful criterion for classifying otherwise typical UC as colitis of indeterminate type, because pouch outcomes are not affected. | 21806956 |
| Inflammation, Chemical injury, Acute Cerebrovascular Accidents | Altered Intercellular Communication | The expression of soluble adhesion molecules inter-cellular adhesion molecule 1 (ICAM-1) and vascular cell adhesion molecule 1 (VCAM-1), besides activation of endothelial cells and transendothelial migration of leukocytes, play an important role in inflammation and progression of ischemic injury after acute stroke. | 21808112 |
| Inflammation | Altered Intercellular Communication | The observed a1-AT deficiency may be due to the chronic inflammation in TPE and associated oxidative stress. | 21808138 |
| ARCN1 gene, Inflammation, Chronic Obstructive Airway Disease, Lung Diseases, Obstructive | Altered Intercellular Communication | Asthma and chronic obstructive pulmonary disease (COPD) are characterised by airway and systemic inflammation, but little is known about differences and similarities in inflammatory markers in patients with obstructive airways disease. | 21808940 |
| Inflammation, Lung Diseases, Obstructive | Altered Intercellular Communication | Levels of serum hs-CRP, IgE, blood eosinophils, and FE(NO) identify distinct aspects of local and systemic inflammation in patients with obstructive airways disease. | 21808940 |
| Inflammation, immunoglobulin A | Altered Intercellular Communication | Chronic periodontit inflammation in old-aged patients was found to be accompanied by imbalance of complement system; sIgA, IgA, IgG and IgM hyperproduction; increased concentrations of IL-8, IL-1alpha and decreased level of IL-4; abrogated NO and its derivatives concentration; increased anti-HSP-70 and homocystein levels in blood and saliva. | 21809634 |
| Primary malignant neoplasm, Anemia | Altered Intercellular Communication | Neoadjuvant treatment should not be given to grave cases of rectal cancer with concomitant perifocal inflammation, anemia and advanced age. | 21809661 |
| Disease, Urinary Calculi, Ulcerative Colitis, Erectile dysfunction | Altered Intercellular Communication | Stone disease is associated with systemic metabolic and hormonal disorders that share common risk factors with erectile dysfunction (ED); however, few studies have investigated the association between ED and urinary calculi (UC). | 21810186 |
| Inflammatory Hepatocellular Adenoma, Non-alcoholic Fatty Liver Disease, Fatty degeneration, Abnormality of mitochondrial metabolism | Altered Intercellular Communication | Mitochondrial dysfunction plays a central role in the general pathogenesis of non-alcoholic fatty liver disease (NAFLD), increasing the risk of developing steatosis and subsequent hepatocellular inflammation. | 21810560 |
| Inflammation | Altered Intercellular Communication | Single high-fat meals containing sequentially four different full-fat dairy foods did not increase eight circulating biomarkers related to inflammation or atherogenesis. | 21811291 |
| Inflammation, Venous Thrombosis, Chronic Lymphocytic Leukemia, Endothelial dysfunction | Altered Intercellular Communication | Inflammation, TNFa and endothelial dysfunction link lenalidomide to venous thrombosis in chronic lymphocytic leukemia. | 21812019 |
| Inflammation | Altered Intercellular Communication | Pseudomelanocytic nests in the setting of lichenoid inflammation can mimic atypical melanocytic proliferations. | 21812802 |
| Kidney Failure, Chronic, Thrombocytosis, Childhood Ataxia with Central Nervous System Hypomyelinization | Altered Intercellular Communication | We hypothesized that ESRD patients with relative thrombocytosis (platelet count >300 x 10(3)/mL) have a higher mortality rate and that this association may be related to malnutrition-inflammation cachexia syndrome (MICS). | 21813809 |
| Paresis, Myasthenia Gravis, Autoimmune Disorder, CTCAE | Altered Intercellular Communication | Myasthenia gravis (MG) is an autoimmune disorder characterized by a defect in synaptic transmission at the neuromuscular junction causing fluctuating muscle weakness with a decremental response to repetitive nerve stimulation or altered jitter in single-fiber electromyography (EMG). | 21814823 |
| Glaucoma, CTCAE, Vitreous inflammatory cells | Altered Intercellular Communication | Her right eye required goniosynechiolysis in order to cure a secondary glaucoma, and the left eye required vitrectomy in order to cure vitreous inflammation. | 21815489 |
| Sample Size Calculation, Inflammation | Altered Intercellular Communication | Hong Kong Chinese adults with SSc seem to exhibit higher levels of periodontal inflammation and wider radiographic periodontal ligament spaces than age- and sex-matched controls. | 21815717 |
| Refractory anemias, Inflammation, Metabolic Syndrome X | Altered Intercellular Communication | The duration of RA was associated with metabolic syndrome, implicating the role of inflammation in metabolic syndrome development. | 21816020 |
| Icterus, Cholecystitis | Altered Intercellular Communication | However, neither jaundice nor gallbladder inflammation was predictive of CDL in this study. | 21816699 |
| Inflammation, Cardiovascular Diseases | Altered Intercellular Communication | Inflammation, as measured by the circulating inflammatory marker high-sensitivity C-reactive protein (hsCRP), has been associated with cardiovascular disease. | 21816845 |
| HMGCL gene, Inflammation, Edema, Pain Distress Question | Altered Intercellular Communication | Chief complaints of HL include inflammation, edema, pain, and reduced flexibility. | 21816996 |
| Cessation of life, Inflammation, Chronic Kidney Diseases, Cardiovascular Diseases | Altered Intercellular Communication | Chronic kidney disease (CKD) is characterized by chronic inflammation, considered a nontraditional risk factor for cardiovascular disease, the major cause of death in CKD. | 21817129 |
| Airway structure, ARCN1 gene, Chronic Obstructive Airway Disease | Altered Intercellular Communication | On-going airway inflammation is characteristic for the pathophysiology of chronic obstructive pulmonary disease (COPD). | 21818276 |
| Inflammation | Altered Intercellular Communication | Accelerated telomere attrition is associated with relative household income, diet and inflammation in the pSoBid cohort. | 21818333 |
| Psoriasis | Altered Intercellular Communication | Psoriasis is a chronic inflammatory condition that occurs worldwide; however, few studies have examined this condition in non-Caucasian populations. | 21818507 |
| Inflammation, Depression, CTCAE | Altered Intercellular Communication | Depression and smoking: mediating role of vagal tone and inflammation. | 21818530 |
| Inflammation, Depression, CTCAE, Smoking | Altered Intercellular Communication | Smoking and depression are each associated with inflammation and vagal tone. | 21818530 |
| Inflammation, Cachexia, Cardiovascular Diseases | Altered Intercellular Communication | Wasting is common in hemodialysis patients and often is accompanied by cardiovascular disease and inflammation. | 21820222 |
| Sclerosis, Inflammation | Altered Intercellular Communication | Presently, OK-432 (Picibanil((r))) is the preferred sclerosant and when administered intralesionally will result in inflammation, sclerosis, and cicatricial contraction of the lesion. | 21820291 |
| Inflammation, Coronary Artery Disease | Altered Intercellular Communication | Red cell distribution width (RDW) is associated with morbidity and mortality in coronary artery disease (CAD), but the connection of RDW with chronic inflammation is equivocal. | 21821014 |
| Inflammation, Bipolar Disorder, Metabolic Syndrome X, Atherosclerosis | Altered Intercellular Communication | Depressive symptoms and sub-clinical atherosclerosis in Africans: role of metabolic syndrome, inflammation and sympathoadrenal function. | 21821058 |
| Inflammation, glycation | Altered Intercellular Communication | The calcium-binding protein S100A12 (EN-RAGE) causes inflammation through interaction with the multiligand receptor for advanced glycation end products (RAGE). | 21822023 |
| Inflammation, Decreased renal function | Altered Intercellular Communication | Although S100A12 levels were not elevated in patients with decreased kidney function, a relation to markers of inflammation was found. | 21822023 |
| vascular inflammations | Altered Intercellular Communication | Increased oxidative stress promotes vascular inflammation and is a common pathway involved in endothelial damage. | 21822395 |
| Inflammation | Altered Intercellular Communication | The time of exhibition suggests in parallel that the progressive increase of inflammation and/or oxidative stress plays a direct role in telomere shortening. | 21824049 |
| Bronchitis | Altered Intercellular Communication | One case of non-asthmatic eosinophilic bronchitis due to methylene diphenil isocyanates has been reported, but a similar condition in the instance of neutrophilic bronchial inflammation has never been described. | 21824062 |
| Asthma, Occupational, Bronchitis | Altered Intercellular Communication | The results of our case suggest that the occurrence of a neutrophilic bronchial inflammation without the functional characteristics of occupational asthma as a consequence of exposure to toluene diisocyanate may also be considered, suggesting a diagnosis of occupational non-asthmatic neutrophilic bronchitis. | 21824062 |
| Inflammation, Dyssomnias, Behavioral Symptoms, Breast Carcinoma, Depression, CTCAE, Fatigue | Altered Intercellular Communication | Inflammation and behavioral symptoms after breast cancer treatment: do fatigue, depression, and sleep disturbance share a common underlying mechanism? | 21825266 |
| Dyssomnias, Depression, CTCAE, Fatigue | Altered Intercellular Communication | Results also suggest that fatigue, sleep disturbance, and depression may stem from distinct biologic processes in post-treatment survivors, with inflammatory signaling contributing relatively specifically to fatigue. | 21825266 |
| Inflammation, Hemorrhage, Attachment (action), Periodontitis | Altered Intercellular Communication | Based on gum inflammation, bleeding on probing, periodontal pocket depth and attachment loss, patients were further divided into mild, moderate and severe periodontitis groups. | 21826136 |
| Inflammation, Neoplasms | Altered Intercellular Communication | Inflammation is a component of tumour progression mechanisms. | 21826665 |
| Inflammation, Urinary Bladder Diseases | Altered Intercellular Communication | Increased serum and urinary NGF levels in patients with OAB refractory to antimuscarinic treatment suggest these bladder disorders might be caused by chronic inflammation. | 21826717 |
| Inflammation, Erythema, Lymphedema | Altered Intercellular Communication | The scrotum was minimally tender, with an intact skin bereft of erythema or inflammation, lower limb lymphedema, inguinal/crural lymphadenopathy. | 21826882 |
| Gingivitis, Dental Plaque | Altered Intercellular Communication | Individuals with regular dental visits retained more teeth but the frequency of dental visits had no impact on plaque deposits, gingival inflammation, or alveolar bone levels. | 21827016 |
| Inflammation, melanoma | Altered Intercellular Communication | Since fistulae experience persistent inflammation, the fact that this melanoma harbours a BRAF mutation strengthens the view that oxidative stress caused by inflammatory processes plays an important role in the genesis of BRAF gene mutations. | 21827678 |
| Inflammation, Lung Diseases, Interstitial, Lung diseases, Carcinoma of lung | Altered Intercellular Communication | Inflammation and pulmonary diseases, including interstitial lung diseases, are associated with increased lung cancer risk. | 21828236 |
| Bipolar Disorder | Altered Intercellular Communication | This observation remained unaltered after additional adjustments for chronic inflammation-related disorders, the use of inflammation-modulating medications and depressive symptoms. | 21829048 |
| Inflammation, Obesity, Atherosclerosis | Altered Intercellular Communication | Obesity modifies the association between plasma phospholipid polyunsaturated fatty acids and markers of inflammation: the Multi-Ethnic Study of Atherosclerosis. | 21829163 |
| Disease, Inflammation, Obesity, Atherosclerosis | Altered Intercellular Communication | Systemic inflammation is a well-known risk factor for diseases such as atherosclerosis and is augmented by the presence of obesity. | 21829163 |
| Inflammation, Asthenia, Deglutition Disorders, Swallowing painful | Altered Intercellular Communication | Mucosal inflammation, asthenia, odynophagia, and dysphagia were the most commonly reported adverse events with lapatinib. | 21829197 |
| Inflammation | Altered Intercellular Communication | Renal patients were characterized by higher OS and inflammation than healthy subjects. | 21829457 |
| TG gene, Inflammation | Altered Intercellular Communication | Inflammation correlated strongly with TG, VLDL-cholesterol, apolipoprotein (apo) C-III and apoC-III bound to apoB-containing lipoproteins, but not with either total cholesterol or LDL-cholesterol.In conclusion, we have discovered a new inflammatory factor, TG48. | 21829457 |
| Inflammation, In-Stent Restenosis Indicator | Altered Intercellular Communication | Inflammation and in-stent restenosis: the role of serum markers and stent characteristics in carotid artery stenting. | 21829478 |
| Vascular System Injuries | Altered Intercellular Communication | Our findings support the assumption that stent geometry leading to vessel injury as well as periprocedural inflammation during CAS plays a pivotal role in the development of carotid artery ISR. | 21829478 |
| Inflammation, Fibrosis Assessment | Altered Intercellular Communication | Matrix metalloproteinase 13 (MMP13) can degrade fibrillar collagens and elastic microfibrils, and is involved in inflammation and fibrosis. | 21830104 |
| Degenerative polyarthritis, Inflammation | Altered Intercellular Communication | Synovial fibroblasts (SFs) contribute to the development of osteoarthritis (OA) by the secretion of a wide range of pro-inflammatory mediators, including cytokines and lipid mediators of inflammation. | 21830213 |
| Degenerative polyarthritis, Inflammation | Altered Intercellular Communication | Previous studies suggest that electromagnetic fields (EMFs) may represent a potential therapeutic approach to limit cartilage degradation and control inflammation associated to OA, and that they may act through the adenosine pathway. | 21830213 |
| Inflammation, Arthropathy | Altered Intercellular Communication | Taken together, these results open new clinical perspectives to the control of inflammation associated to joint diseases. | 21830213 |
| Inflammatory Bowel Diseases, Gastrointestinal inflammation | Altered Intercellular Communication | Given the accumulating evidence for an important role of PXR in intestinal inflammation, further analyses are required to investigate the functional and pharmacogenetic implications of these PXR/NR1I2 gene variants in IBD. | 21830270 |
| Inflammatory Bowel Diseases, Inflammation | Altered Intercellular Communication | We speculate that aging, rather than inflammation per se, promotes CIMP(+) CRCs in IBD patients. | 21830278 |
| Inflammation, Chronic heart failure, Congestive heart failure | Altered Intercellular Communication | Chronic heart failure (CHF) is associated with increased inflammation, and exercise training has in some studies been shown to have anti-inflammatory effect, although controversies exist. | 21831004 |
| Inflammation, Congestive heart failure | Altered Intercellular Communication | Measures of CHF severity were significantly correlated with several markers of inflammation. | 21831004 |
| Inflammation, Primary malignant neoplasm | Altered Intercellular Communication | The TGF-b superfamily cytokine, MIC-1/GDF15: a pleotrophic cytokine with roles in inflammation, cancer and metabolism. | 21831009 |
| Inflammation, Primary malignant neoplasm, Cardiovascular Diseases | Altered Intercellular Communication | Macrophage inhibitory cytokine-1 (MIC-1/GDF15) is associated with cardiovascular disease, inflammation, body weight regulation and cancer. | 21831009 |
| Primary malignant neoplasm, Chronic inflammation, Obesity | Altered Intercellular Communication | Available data suggest MIC-1/GDF15 may be an important molecule mediating the interplay between cancer, obesity and chronic inflammation. | 21831009 |
| palladium, Inflammation | Altered Intercellular Communication | Inflammation may be one possible pathway to link PD with CVD. | 21831372 |
| Inflammation, Ectopic kidney | Altered Intercellular Communication | The CTA revealed significant thickening of the aortic wall, suggestive of aortic inflammation, the presence of crossed renal ectopia with fusion, and numerous anomalous renal arteries. | 21831590 |
| Inflammation, Aneurysm | Altered Intercellular Communication | Given the aortic inflammation, an open repair approach was considered high risk compared with an endovascular aneurysm repair (EVAR). | 21831590 |
| Airway structure | Altered Intercellular Communication | Exhaled nitric oxide (ENO) is used as a marker of airway inflammation. | 21832821 |
| Inflammatory Bowel Diseases, CDISC Integrated Basic Data Structure Dataset, Ulcerative Colitis, Crohn Disease, Inflammation of large intestine | Altered Intercellular Communication | Inflammatory bowel diseases (IBDs), Crohn's disease, and ulcerative colitis (UC), are multifactorial disorders, characterized by chronic inflammation of the intestine. | 21832969 |
| Inflammatory Bowel Diseases, Gastrointestinal inflammation | Altered Intercellular Communication | Our study adds DBP to the list of potential genes that contribute to the complex genetic etiology of IBD, and further emphasizes the association between vitamin D homeostasis and intestinal inflammation. | 21832969 |
| Inflammation, Aortic Stiffness | Altered Intercellular Communication | Aortic stiffness, inflammation, denutrition and prognosis in the oldest people. | 21833025 |
| Inflammation, Lupus Erythematosus | Altered Intercellular Communication | Arterial stiffening, wave reflection, and inflammation in habitually exercising systemic lupus erythematosus patients. | 21833040 |
| Inflammation, Hypertension, CTCAE, Cardiovascular Diseases | Altered Intercellular Communication | Chronic systemic inflammation has been implicated in the pathogenesis of hypertension and cardiovascular disease. | 21833040 |
| Inflammation, Lupus Erythematosus, Systemic, Autoimmune Diseases, Cardiovascular Diseases, Lupus Erythematosus | Altered Intercellular Communication | Systemic lupus erythematosus (SLE) is an autoimmune disease characterized by chronic inflammation and an increased risk for cardiovascular disease. | 21833040 |
| Arterial Stiffness, Inflammation | Altered Intercellular Communication | Furthermore, greater arterial stiffness was associated with higher inflammatory markers, suggesting that need for studies on inflammation and SLE-associated arterial stiffening. | 21833040 |
| Inflammation, NLRP3 gene | Altered Intercellular Communication | FCAS results in cold-induced cytokine dysregulation and systemic inflammation. | 21833523 |
| Inflammation | Altered Intercellular Communication | Chronic inflammation: a poor prognostic factor for endoscopic dacryocystorhinostomy. | 21833563 |
| Inflammation, Fibrosis Assessment, Leucocytic infiltrate | Altered Intercellular Communication | All the specimens were examined for the chronic inflammation related histopathological features (inflammatory cell infiltration, fibrosis and capillary proliferation) and graded according to their severity. | 21833563 |
| Inflammation | Altered Intercellular Communication | However, 9 of 10 patients with unsatisfactory and/or unsuccessful outcome (90%) had severe chronic inflammation of lacrimal sac. | 21833563 |
| Inflammation, Fibrosis Assessment, Leucocytic infiltrate | Altered Intercellular Communication | In subjective assessment, inflammatory cell infiltration (p = 0.050), fibrosis (p = 0.037), capillary proliferation (p = 0.007) and chronic inflammation (p = 0.003) had a statistically significant difference between patients with satisfactory and unsatisfactory outcome. | 21833563 |
| Inflammation, Leucocytic infiltrate | Altered Intercellular Communication | In objective assessment, statistically significant differences were detected between patients with successful and unsuccessful outcome when they compared according to inflammatory cell infiltration (p = 0.027), capillary proliferation (p = 0.007) and chronic inflammation (p = 0.003). | 21833563 |
| Inflammation | Altered Intercellular Communication | Chronic inflammation related histopathological features of variable degree may have a role on En-DCR outcome. | 21833563 |
| Inflammation | Altered Intercellular Communication | Furthermore, gadolinium-enhanced inflammation on brain MRI rapidly disappeared after CBT. | 21834803 |
| Cessation of life, Inflammation | Altered Intercellular Communication | We have previously demonstrated that glia maturation factor (GMF), a brain-specific protein, isolated, sequenced, and cloned in our laboratory, is a prominent mediator of inflammation in the CNS leading to the death of neurons. | 21835226 |
| Inflammation, Plaque, Atherosclerotic | Altered Intercellular Communication | dal-PLAQUE will provide important information on the effects of dalcetrapib on markers of inflammation and atherosclerotic plaque burden and, thereby, on the safety of cholesteryl ester transfer protein modulation with dalcetrapib. | 21835280 |
| Malignant neoplasm of ovary, Pelvic Inflammatory Disease | Altered Intercellular Communication | Whether pelvic inflammation itself accelerates the growth of ovarian cancers or affects cancer-cell differentiation in ways that adversely alter prognosis needs to be investigated. | 21835693 |
| Communicable Diseases, Pancreatic stone, Inflammation | Altered Intercellular Communication | Pancreatic stone protein (PSP)/regenerating protein (reg) is associated with inflammation, infection, and other disease-related stimuli. | 21835904 |
| Inflammation | Altered Intercellular Communication | To conclude, retained PFCL can cause late onset fibrinous inflammation after a quiescent period but surgical intervention may lead to good visual outcome. | 21836352 |
| Inflammation, Lymphadenopathy | Altered Intercellular Communication | We describe a patient who presented with cervical and inguinal lymphadenopathies and high inflammation indexes. | 21837920 |
| Inflammation | Altered Intercellular Communication | Ruptured intraneural cysts and simple cysts share these MRI findings: T2 hyperintense fluid within surrounding intermuscular fascial planes and enhancement with intravenous contrast consistent with inflammation. | 21838077 |
| Inflammation, Steatohepatitis | Altered Intercellular Communication | Visceral fat differs from subcutaneous fat by higher local inflammation and increased release of IL-6 and free fatty acids (FFA) which contribute to hepatic steatosis. | 21839737 |
| Inflammation, Apolipoprotein E | Altered Intercellular Communication | Apolipoprotein E is associated with blood lipids and inflammation in Taiwanese older adults. | 21840004 |
| Lysosomal Storage Diseases, Inflammation, Globoid cell leukodystrophy | Altered Intercellular Communication | One of a family of devastating lysosomal storage disorders, Krabbe disease is characterized by demyelination, psychosine accumulation, and inflammation. | 21840342 |
| Inflammation, GDC AJCC Clinical Stage Terminology | Altered Intercellular Communication | Inflammation is a major factor underlying acute coronary syndromes (ACS). | 21840418 |
| GDC AJCC Clinical Stage Terminology | Altered Intercellular Communication | HDL particles may be remodeled, becoming functionally defective, under the inflammatory conditions seen in ACS. | 21840418 |
| Meningitis | Altered Intercellular Communication | Meningeal inflammation is widespread and linked to cortical pathology in multiple sclerosis. | 21840891 |
| Meningitis | Altered Intercellular Communication | Meningeal inflammation in the form of ectopic lymphoid-like structures has been suggested to play a prominent role in the development of cerebral cortical grey matter pathology in multiple sclerosis. | 21840891 |
| Meningitis | Altered Intercellular Communication | The presence of B cell follicle-like structures was associated with an accompanying quantitative increase in diffuse meningeal inflammation that correlated with the degree of microglial activation and grey matter cortical demyelination. | 21840891 |
| Inflammation, Psoriasis, Atrial Fibrillation by ECG Finding, Ischemic stroke, Chronic inflammatory disorder, Atrial Fibrillation | Altered Intercellular Communication | Psoriasis is a chronic inflammatory disease and inflammation contributes to the pathogenesis of atrial fibrillation (AF) and ischaemic stroke. | 21840930 |
| dendritic lamellar body, Data types - Address | Altered Intercellular Communication | We retrospectively compared CSF concentrations of the neurotransmitter metabolites homovanillic acid (HVA), 5-hydroxyindolacetic acid (5-HIAA), and 3-methoxy-4-hydroxyphenylethyleneglycol (MHPG) and the brain-specific proteins total tau (t-tau), phosphorylated tau protein (p-tau), and amyloid-b42 (Ab42) in 45 patients with AD (mean age 71.6 years; 34 (76%) men; 44 probable AD, 1 definite) and 23 patients with DLB (mean age 71.6 years; 18 (78%) men; 6 possible DLB, 16 probable, 1 definite). | 21841257 |
| dendritic lamellar body, Data types - Address | Altered Intercellular Communication | The concentrations of all neurotransmitter metabolites, as well as those for t-tau and p-tau protein, were significantly lower in DLB compared to AD, irrespective of the diagnostic certainty (i.e., possible or probable). | 21841257 |
| Communicable Diseases, Chlamydia, Inflammation, Coronary Artery Disease | Altered Intercellular Communication | We evaluated the role of inflammation and acute or persistent Chlamydia pneumoniae infection in coronary artery disease (CAD). | 21841301 |
| Inflammation, Neoplasms, Tissue damage, Infection, Irritation | Altered Intercellular Communication | Although hypotheses about altered wound healing mechanisms, influence of chronic inflammation and irritation or tissue damage through infections are conclusive, further investigations are necessary to clarify the exact pathogenetic mechanisms of tumour development in chronic wounds. | 21841717 |
| Inflammation, Edema, Conjunctival hyperemia | Altered Intercellular Communication | Light microscopy revealed decreased edema, fibrin deposition, inflammation and vascular congestion in the trabecular meshwork in specimens with IVB compared to those without IVB. | 21842129 |
| Intraocular inflammation, Uveitis | Altered Intercellular Communication | The synthetic peptides were tested against sera of 110 patients with different uveitis forms, classified according to anatomical location of intraocular inflammation. | 21842131 |
| Colitis, Ischemic, Colitis | Altered Intercellular Communication | Ischaemic colitis (IC) is an inadequate perfusion leading to potentially life-threatening colonic inflammation. | 21842142 |
| Inflammation | Altered Intercellular Communication | Limited information exists, however, regarding the relationship between low-grade inflammation and cognitive function in healthy older adults. | 21843630 |
| Inflammation, Pseudomonas aeruginosa | Altered Intercellular Communication | These microorganisms were associated with increased levels of inflammation, with P. aeruginosa being the most proinflammatory. | 21844026 |
| Multiple Organ Failure, Pneumonitis | Altered Intercellular Communication | Mixed oral flora (MOF) alone was isolated from 165 BAL samples from 112 patients, with 97 of these samples having a bacterial density >=10(5) cfu/mL, and was associated with increased pulmonary inflammation (P < .001). | 21844026 |
| Refractory anemias, Rheumatoid Arthritis, Inflammation, Atherosclerosis | Altered Intercellular Communication | We examined the hypothesis that cystatin C, a novel marker of renal function, is elevated in rheumatoid arthritis (RA) and is associated with inflammation and coronary atherosclerosis. | 21844147 |
| Refractory anemias, Inflammation, Renal Insufficiency | Altered Intercellular Communication | Cystatin C concentrations are higher in RA than controls and may reflect inflammation and undetected subclinical renal dysfunction. | 21844147 |
| Abnormality of the maxillary sinus, Nasal inflammation | Altered Intercellular Communication | Maxillary sinus abnormalities were demonstrated to be associated with maxillary sinus infundibulum narrowing as well as nasal airflow resistance secondary to nonspecific nasal inflammation. | 21846296 |
| Inflammation | Altered Intercellular Communication | Fat mass (FM) in overweight/obese subjects has a primary role in determining low-grade chronic inflammation and, in turn, insulin resistance (IR) and ectopic lipid storage within the liver. | 21846339 |
| Inflammation, Federated States of Micronesia, Obesity | Altered Intercellular Communication | Obesity, aging, and FM influence the growth hormone/insulin-like growth factor (IGF)-I axis, and chronic inflammation might reduce IGF-I signaling. | 21846339 |
| Inflammation, Federated States of Micronesia | Altered Intercellular Communication | We tested the hypothesis that FM, or spleen volume and C-reactive protein (CRP)--all indexes of chronic inflammation--could affect the IGF-I axis status in overweight/obese, independently of HS. | 21846339 |
| Inflammation, Federated States of Micronesia, Obesity | Altered Intercellular Communication | Obesity, aging, and FM influence the growth hormone/insulin-like growth factor (IGF)-I axis, and chronic inflammation might reduce IGF-I signaling. | 21846339 |
| Inflammation, Infection, Diabetes Mellitus | Altered Intercellular Communication | Likewise, chronic inflammation or infections seem to provoke insulin resistance and thereby contribute to the development of diabetes and its complications. | 21848608 |
| Chronic lymphocytic inflammation, Pontine structure, Clippers | Altered Intercellular Communication | Chronic lymphocytic inflammation with pontine perivascular enhancement responsive to steroids (CLIPPERS) is a recently defined inflammatory central nervous system disorder responsive to steroids with characteristic magnetic resonance imaging (MRI) features. | 21848680 |
| Inflammation, Ulcerative Colitis | Altered Intercellular Communication | Rapid resolution of symptoms and endoscopic inflammation in ulcerative colitis (UC) represent important treatment goals. | 21848857 |
| Proteinuria, Inflammation | Altered Intercellular Communication | We prospectively examined the relationships of WBC count, as a marker of inflammation, with two outcomes: proteinuria and low estimated glomerular filtration rate (eGFR). | 21849773 |
| Inflammation, Diabetic Retinopathy | Altered Intercellular Communication | High-mobility group box-1 and biomarkers of inflammation in the vitreous from patients with proliferative diabetic retinopathy. | 21850157 |
| Inflammation, PDR gene | Altered Intercellular Communication | Subclinical chronic inflammation might contribute to the progression of PDR. | 21850157 |
| Inflammation, Malignant Neoplasms | Altered Intercellular Communication | Xanthogranulomatous inflammation (XGI) is a special type of inflammation presenting as mass lesions and mimicking malignant tumors. | 21850556 |
| Inflammation, Myositis | Altered Intercellular Communication | Our observations that p75NTR is upregulated on skeletal myofibres in inflammatory myopathies in vivo and promotes resistance to inflammatory mediators in vitro suggest that neurotrophin signalling through p75NTR may mediate a tissue-protective response to inflammation in skeletal myofibres. | 21851375 |
| Inflammation, Diabetes Mellitus, Non-Insulin-Dependent, Thrombophilia | Altered Intercellular Communication | Impaired glucose metabolism and type 2 diabetes are associated with hypercoagulability: potential role of central adiposity and low-grade inflammation--the Hoorn Study. | 21851966 |
| Immunoglobulin M, Inflammation, square decimeter | Altered Intercellular Communication | Individuals with IGM or DM2 had up to 4% higher thrombin generation compared with NGM, which may be explained, to a great extent, by the greater levels of central adiposity and related low-grade inflammation characterizing these individuals. | 21851966 |
| Peripheral Vascular Diseases, Inflammation, Endothelial dysfunction | Altered Intercellular Communication | Anti-endothelial cell antibodies are associated with peripheral arterial disease and markers of endothelial dysfunction and inflammation. | 21852269 |
| Steatohepatitis, Inflammation, Meibomian gland dysfunction | Altered Intercellular Communication | Increased visceral fat, as opposed to subcutaneous/gluteal, most strongly relates to key metabolic dysfunctions including insulin resistance, hepatic steatosis, and inflammation. | 21852815 |
| Crohn Disease, Inflammation, Hypertrophy | Altered Intercellular Communication | Mesenteric fat hypertrophy in patients with Crohn's disease and in experimental rodent models of gut inflammation suggest that impaired gut barrier function with increased leakage of gut-derived antigens may drive visceral lipid deposition. | 21852815 |
| Presenile dementia, Inflammation, Impaired cognition | Altered Intercellular Communication | Inflammation may contribute to cognitive decline and dementia. | 21853262 |
| Cognition Disorders, Inflammation, Depression, CTCAE | Altered Intercellular Communication | Thus, markers of systemic inflammation are related to cognitive deficits in a non-clinical community-dwelling elderly population, independent of depression, cardiovascular or metabolic risk factors, or presence of apolipoprotein e4 genotype. | 21853262 |
| Inflammation | Altered Intercellular Communication | A time later, after complete remittance of local inflammation, the pancreas was anastomosed to the jejunum. | 21853755 |
| Inflammation | Altered Intercellular Communication | No reaction of ophthalmic inflammation was reported 5 days after injection, moreover foreign body sensation and bloodshot were absent. | 21853949 |
| HIV Antigens, Toxic effect | Altered Intercellular Communication | Although traditional risk factors of aging as well as treatment toxicity contribute to this risk, many investigators consider chronic HIV-associated inflammation a significant factor in such end-organ disease. | 21854232 |
| Inflammation, Psychological suppression | Altered Intercellular Communication | Despite effective viral suppression, chronic inflammation persists at levels higher than in uninfected people, yet the stimuli for the inflammation and the mechanism by which inflammation persists and promotes disease pathology remain incompletely understood. | 21854232 |
| Inflammation, Erythema, Hematoma | Altered Intercellular Communication | Redness and induration at the site of injection are commonly reported and are considered to be the result of local inflammation or hematoma formation, although other atypical reactions can occur. | 21854416 |
| Inflammation | Altered Intercellular Communication | The level of detected HBV-DNA-particles was low, however, indicating that the HBV infection alone could not be responsible for the inflammation. | 21854665 |
| Excessive tearing, Inflammation, Erythema, Pain Distress Question | Altered Intercellular Communication | nasolacrimal sac inflammation, characterised by epiphora, pain, erythema, sac dilation and lacrimal punctum swelling). | 21854672 |
| Extrinsic allergic alveolitis, Bronchiolitis Obliterans, histiocytic, Fibrosis Assessment | Altered Intercellular Communication | Histopathologic features assessed in each case included those characteristic of subacute hypersensitivity pneumonitis (bronchiolocentric chronic inflammation, histiocytic aggregates, and bronchiolitis obliterans), those associated with acute inflammation (fibrin deposition and neutrophilic infiltrate), and fibrosis. | 21855112 |
| Extrinsic allergic alveolitis, Granulomatous inflammation | Altered Intercellular Communication | Increased fibrin deposition and neutrophilic infiltrate may characterize acute hypersensitivity pneumonitis or abrupt exacerbation of hypersensitivity pneumonitis, and these along with characteristic features of subacute hypersensitivity pneumonitis (granulomatous inflammation and bronchiolocentricity) are sufficient to establish a morphologic diagnosis, particularly in conjunction with clinicoradiologic features. | 21855112 |
| ARCN1 gene, Inflammation, Blood Cells | Altered Intercellular Communication | Novel pharmacological strategies are aimed at the resolution of systemic inflammation in COPD potentiating peripheral blood T-cell (PBT-cell) apoptosis. | 21855166 |
| Airway structure, ARCN1 gene | Altered Intercellular Communication | Although muscarinic acetylcholine receptors (mAChRs) M(3) and choline-acetyltransferase (ChAT) participate in the airway inflammation of COPD, their role in PBT-cell apoptosis remains unexplained. | 21855166 |
| ARCN1 gene, Inflammation | Altered Intercellular Communication | It provides novel putative pharmacological targets for the resolution of systemic inflammation in COPD. | 21855166 |
| Inflammation, Myositis, CTCAE 5.0, Idiopathic Inflammatory Myopathies, Polymyositis, Heat-Shock Response, Dermatomyositis, Muscular Dystrophy, Duchenne | Altered Intercellular Communication | We examined the effects of chronic inflammation on the distribution of heat shock protein families 70 and 90 using immunofluorescence and Western blotting, in muscle biopsies from 33 idiopathic inflammatory myopathy patients [aged 26-66 (dermatomyositis), 17-78 (polymyositis) and 57-80 (sporadic inclusion body myositis) years], and seven Duchenne muscular dystrophy patients (aged 3-19 years). | 21855341 |
| Inflammation, Myopathy, Myositis, CTCAE 5.0 | Altered Intercellular Communication | Sporadic inclusion body myositis (IBM) is a muscle disease with two separate pathogenic components, degeneration and inflammation. | 21855683 |
| Cataract, Intraocular inflammation, Edema | Altered Intercellular Communication | Single perioperative subconjunctival steroid depot versus postoperative steroid eyedrops to prevent intraocular inflammation and macular edema after cataract surgery. | 21855759 |
| Airway structure | Altered Intercellular Communication | The mechanism is unclear, but the effect may be mediated through induced airways inflammation. | 21856701 |
| Inflammation, Obesity | Altered Intercellular Communication | Adenosine, an endogenous anti-inflammatory metabolite, is increased in response to inflammation produced by adipose tissue in obesity. | 21859364 |
| Granulomatous inflammation, Sarcoidosis, Myocarditis, CTCAE 5.0, Giant cell myocarditis | Altered Intercellular Communication | We observed marked reduction in immunoreactive signal for plakoglobin at cardiac myocyte junctions in patients with sarcoidosis and giant cell myocarditis, both highly arrhythmogenic forms of myocarditis associated with granulomatous inflammation. | 21859801 |
| Inflammation, Chronic somatic dysfunction, Endothelial dysfunction | Altered Intercellular Communication | Oxidative stress may provide a link between endothelial dysfunction, inflammation, and immune activation and the development of chronic venous dysfunction. | 21860369 |
| Inflammation, Fibrosis Assessment | Altered Intercellular Communication | Retroperitoneal fibrosis (RPF) is a rare disease with unclear etiology, which is characterized by chronic non-specific inflammation of the retroperitoneum. | 21860546 |
| Hypophysitis, CTCAE, Inflammation, Autoimmune Diseases | Altered Intercellular Communication | Hypophysitis is a chronic inflammation of the pituitary gland often caused by autoimmunity. | 21861119 |
| Inflammation, Diabetes Mellitus, Endothelial dysfunction, Coronary heart disease | Altered Intercellular Communication | The greater adverse influence of diabetes per se on adiposity and HOMA-IR and downstream blood pressure, lipids, endothelial dysfunction and systemic inflammation in women compared with men may contribute to their greater relative risk of coronary heart disease. | 21861177 |
| Uveitis | Altered Intercellular Communication | All French rheumatologists, pediatric rheumatologists, and internal medicine practitioners registered on the Club Rhumatismes et Inflammation web site were contacted in an attempt to declare the cases of new onset of uveitis, diagnosed by an ophthalmologist, in patients treated with TNF blockers. | 21862108 |
| Cessation of life, Cardiac dysfunction | Altered Intercellular Communication | While elevated BNP, an abnormality of cardiac neurohormones, is known to be an independent marker of death or re-admission, it remains to be clarified whether there is also a strong predictor directly related to cardiac dysfunction. | 21862290 |
| Inflammation | Altered Intercellular Communication | Four patients showed clinical resolution of DS (no inflammation) after PDT sessions, and only 1 subject demonstrated reduction in palatal inflammation. | 21862363 |
| Inflammation, Trauma, Nervous System | Altered Intercellular Communication | Although intraneural injections have not resulted in clinically detectable neurologic injury in small studies in human subjects, intraneural injections result in postinjection inflammation in animal models. | 21862889 |
| Granulomatous inflammation, Chorioamnionitis, Pneumonia | Altered Intercellular Communication | Following elective pregnancy termination, microscopic examination and molecular analysis demonstrated Candida lusitaniae chorioamnionitis and pneumonia in all 3 fetuses associated with granulomatous inflammation. | 21864122 |
| Necrotizing granulomatous inflammation, Infective pneumonia acquired prenatally | Altered Intercellular Communication | We also show here that C. lusitaniae can cause granulomatous intraplacental inflammation and intrauterine pneumonia. | 21864122 |
| Inflammation | Altered Intercellular Communication | Zingiber officinale and Glycyrrhiza uralensis are found to have the ability to reduce pro-inflammatory cytokine production, to inhibit lipopolisaccharide-induced macrophage activation and function, and to lessen the bacterial load and suppress acute and chronic inflammation. | 21864392 |
| Inflammation, Overweight | Altered Intercellular Communication | Increasing the vegetable intake dose is associated with a rise in plasma carotenoids without modifying oxidative stress or inflammation in overweight or obese postmenopausal women. | 21865569 |
| Inflammation, Overweight | Altered Intercellular Communication | We conducted a 3-dose, crossover feeding trial to test the hypothesis that vegetable intake is associated in a dose-dependent manner with increased plasma carotenoids and subsequently reduced oxidative stress and inflammation in 49 overweight, postmenopausal women. | 21865569 |
| Inflammation, Ischemia | Altered Intercellular Communication | In the AMI setting, AF is frequently brief and attributed to acute haemodynamic changes, inflammation or ischaemia. | 21866303 |
| Heart failure, Hypoalbuminemia | Altered Intercellular Communication | Hypoalbuminemia is a common condition in patients with heart failure and is mainly related to the malnutrition-inflammation complex syndrome. | 21867985 |
| Inflammation, Myocardial, Heart failure, Hypoalbuminemia, Fluid overload | Altered Intercellular Communication | Hypoalbuminemia may also contribute to the progression of heart failure by favoring myocardial edema, volume overload, diuretic resistance and exacerbation of oxidative stress and inflammation. | 21867985 |
| Autoimmune Diseases, Lupus Erythematosus, Systemic | Altered Intercellular Communication | Gonadotropin releasing hormone agonists may minimize cyclophosphamide associated gonadotoxicity in SLE and autoimmune diseases. | 21868068 |
| Hyperlipidemia, No metabolic abnormalities, Inflammation, Obesity | Altered Intercellular Communication | In particular, no single agent can correct multiple metabolic abnormalities such as insulin resistance, hyperlipidemia, inflammation, obesity, and fat distribution. | 21869685 |
| Inflammation, Autoinflammatory disorder, Fever, CTCAE, Tumor necrosis, Periodic Fever Syndrome, Trap medical device | Altered Intercellular Communication | Tumor necrosis factor receptor-associated periodic fever syndrome (TRAPS) is a rare systemic autoinflammatory disorder characterized by recurrent episodes of fever and localized inflammation of different organs. | 21869706 |
| Inflammation, Endothelial dysfunction, Diabetes Mellitus, Non-Insulin-Dependent, Cardiovascular Diseases | Altered Intercellular Communication | Low-grade inflammation and endothelial dysfunction may play a role in the pathogenesis of type 2 diabetes and cardiovascular disease. | 21870174 |
| Inflammation, Endothelial dysfunction, Overweight, Diabetes Mellitus | Altered Intercellular Communication | Our results suggest that the combined effect of fatty fish, bilberries and wholegrain products may improve endothelial dysfunction and inflammation in overweight and obese individuals at high risk of developing diabetes. | 21870174 |
| Degenerative polyarthritis, Inflammation | Altered Intercellular Communication | Osteoarthritis (OA) is characterized by cartilage attrition, subchondral bone remodeling, osteophyte formation and synovial inflammation. | 21870330 |
| Degenerative polyarthritis, Inflammation, Abnormality of mitochondrial metabolism | Altered Intercellular Communication | Perturbed homeostasis caused by inflammation, oxidative stress, mitochondrial dysfunction and proapoptotic/antiapoptotic dysregulation is known to impair chondrocyte survival in joint microenvironments and contribute to OA pathogenesis. | 21870330 |
| Urine microscopy leukocytes present finding, Urolithiasis, Urethritis | Altered Intercellular Communication | As shown by reduction of leukocyturia and crystalluria, increased 24-h diuresis in patients with urolithiasis after exposure to ECSWL, a positive effect was achieved on urethral inflammation. | 21870476 |
| Communicable Diseases, Pericardial Effusion, CTCAE, Inflammation, Hypothyroidism | Altered Intercellular Communication | Pericardial effusion with pretamponade is an exceptional complication of prolonged hypothyroidism that should be considered in patients presenting with large longstanding but well tolerated pericardial effusion with no evidence of infection or inflammation. | 21870563 |
| Inflammation, Alveolar Bone Loss | Altered Intercellular Communication | In both natural teeth and dental implant groups, despite higher MBL measures, cathepsin-K activity, and GCF/PISF volumes with the presence of inflammation, it was the presence of alveolar bone loss that lead to significantly higher values for these parameters. | 21870974 |
| Inflammation, Fibrosis Assessment | Altered Intercellular Communication | After 2 years, owing to inflammation and fibrosis, a T-tube was inserted from the glottis to the tracheal bifurcation. | 21871319 |
| Inflammation, Brain Injuries | Altered Intercellular Communication | Therefore, common, functionally relevant genetic variants in the key components of this pathway have been associated with greater inflammation post-ictus, further cerebral damage, and ultimately, a worse outcome. | 21871809 |
| vascular inflammations, Coronary Arteriosclerosis | Altered Intercellular Communication | We aimed to determine if an abnormal ankle-brachial index (ABI) value as a surrogate of atherosclerotic disease and vascular inflammation provides information on 1-year risk of cardiovascular events after DES implantation. | 21872197 |
| Inflammation, Observation Method - Coagulation, Venous Thromboembolism | Altered Intercellular Communication | Since inflammation and coagulation are tightly coupled, we postulated that RBC transfusion may be associated with the development of venous thromboembolic phenomena. | 21872295 |
| Communicable Diseases, Inflammation | Altered Intercellular Communication | Hemostasis and inflammation are two tightly interrelated systems in the host's response to infection. | 21872299 |
| Sepsis, Inflammation | Altered Intercellular Communication | Thrombin generation in sepsis plays a crucial role in enhancing and modulation of inflammation. | 21872299 |
| Inflammation, Malignant Neoplasms, Tuberculosis | Altered Intercellular Communication | Among the 44 patients with sufficient biopsy specimens, 17 patients had malignancy, 12 had tuberculosis, and 15 had nonspecific inflammation. | 21873256 |
| Inflammation, Malignant Neoplasms, Tuberculosis | Altered Intercellular Communication | The diagnostic accuracy of US-guided percutaneous biopsy of reticular infiltrations in the mesentery and omentum was 84%; the sensitivity and specificity was, respectively, 89% and 100% for malignancy, 75% and 100% for tuberculosis, and 90% and 83% for nonspecific inflammation. | 21873256 |
| Inflammation | Altered Intercellular Communication | Of the 198 joints examined, signs of inflammation were detected by MRI in 49 (24.7%) and by scintigraphy in 48 (24.2%) joints, with agreement between the two methods in 44 joints. | 21873267 |
| Inflammation | Altered Intercellular Communication | In another four joints, scintigraphy was positive and MRI negative for signs of inflammation. | 21873267 |
| Inflammation, Diabetes Mellitus, Non-Insulin-Dependent | Altered Intercellular Communication | Effect of serum 25-hydroxyvitamin D on risk for type 2 diabetes may be partially mediated by subclinical inflammation: results from the MONICA/KORA Augsburg study. | 21873558 |
| Inflammation, Diabetes Mellitus, Non-Insulin-Dependent | Altered Intercellular Communication | To assess the association between serum 25-hydroxyvitamin D (25-OHD) and incident type 2 diabetes and to determine whether the association is mediated by subclinical inflammation. | 21873558 |
| Inflammation, Diabetes Mellitus, Non-Insulin-Dependent | Altered Intercellular Communication | Vitamin D status is inversely related to type 2 diabetes risk and our data suggest that this association may be partially mediated by subclinical inflammation. | 21873558 |
| Inflammation, GDC Disease Response Terminology | Altered Intercellular Communication | This result indicates that systemic subclinical inflammation is related with DR, and neutrophil-mediated inflammation may play an important role in the pathogenesis of DR. | 21873679 |
| Inflammation, Ischemic stroke | Altered Intercellular Communication | Association of clinical and aetiologic subtype of acute ischaemic stroke with inflammation, oxidative stress and vascular function: a cross-sectional observational study. | 21873941 |
| Inflammation, physiopathological, Cerebrovascular accident | Altered Intercellular Communication | The role of inflammation, vascular dysfunction and oxidative stress in the pathophysiology of different stroke subtypes is not well understood. | 21873941 |
| Inflammation, Ischemic stroke | Altered Intercellular Communication | We aimed to determine if the clinical and aetiologic subtype of acute ischaemic stroke influences systemic markers of vascular function, inflammation and oxidative stress. | 21873941 |
| Inflammation, Cerebrovascular accident | Altered Intercellular Communication | Stroke severity (NIHSS score and S100B concentration); systemic markers of inflammation (high sensitivity C-reactive protein [hs-CRP] and fibrinogen), endothelial activation (E-selectin), endothelial cell damage (von Willebrand factor activity), and oxidative stress (F2-isoprostanes) were measured. | 21873941 |
| Inflammation, Ischemic stroke, Cerebrovascular accident | Altered Intercellular Communication | These data suggest that stroke aetiology and clinical syndrome may not be important independent determinants of the degree of systemic inflammation, oxidative stress or endothelial function in acute ischaemic stroke. | 21873941 |
| Inflammation, Ischemic stroke, Cerebrovascular accident | Altered Intercellular Communication | Other factors, including stroke severity, pre-morbid inflammation and co-morbidity may explain variations among groups of participants with different subtypes of acute ischaemic stroke. | 21873941 |
| Inflammation, Lichenoid, Necrosis, Pseudomembrane, Ulcer, Erythema | Altered Intercellular Communication | Clinical and histopathological features were similar in both acute and chronic oral GVHD and included mucosal lichenoid changes, erythema, ulcerations and pseudomembranes, satellite necrosis, apoptotic bodies and lichenoid interface inflammation. | 21873943 |
| Degenerative polyarthritis, Inflammation | Altered Intercellular Communication | The increase of PON1 activity in patients' serum in relation to the control groups indicates a probable pathogenic role of the increased formation of reactive oxygen species in the course of OA and may suggest acute inflammation of the synovial joint. | 21873946 |
| Xanthogranulomatous inflammation | Altered Intercellular Communication | These microscopic findings were consistent with xanthogranulomatous inflammation, and the lesion was diagnosed as XGP. | 21874438 |
| Inflammation, Obesity | Altered Intercellular Communication | Maternal obesity associated with inflammation in their children. | 21874618 |
| Inflammation, Glomerulonephritis, Kidney Diseases | Altered Intercellular Communication | Acute glomerulonephritis (AGN) is a type of renal disease which indicates the inflammation of glomerulus and nephrons. | 21874641 |
| Granulomatous inflammation, Necrosis | Altered Intercellular Communication | Biopsy of the lung infiltrate by transthoracic computed tomography guided histology needle, showed granulomatous inflammation with necrosis. | 21874738 |
| Inflammation | Altered Intercellular Communication | Proposed biological pathways imply that particle-induced pulmonary and systemic inflammation play a role in activating the vascular endothelium and altering vascular function. | 21874957 |
| Inflammation, Diabetic Angiopathies, Obesity | Altered Intercellular Communication | According to the concept of adipose tissue expandability, the vascular complications of obesity are related less to the amount of stored fat than to the low-grade inflammation that excess fat storage may elicit. | 21875718 |
| Inflammation, Cardiovascular Diseases | Altered Intercellular Communication | These findings imply that public health strategies aimed at early prevention of cardiovascular disease may need to target low-grade inflammation rather than only BMI or adiposity. | 21875718 |
| Communicable Diseases, Mildly reduced visual acuity, Inflammation | Altered Intercellular Communication | There were no cases of infection, significant inflammation, epithelial problems and reduction in visual acuity. | 21876589 |
| Alveolar damage | Altered Intercellular Communication | The most prevalent pulmonary histopathological pattern was diffuse alveolar damage, which was associated with different inflammatory conditions. | 21876973 |
| Granulomatous inflammation, Chronic Active Colitis, Tethered Cord Syndrome | Altered Intercellular Communication | On histologic examination, all patients with the cord colitis syndrome had chronic active colitis, with granulomatous inflammation present in 7 of 11 patients (64%). | 21879899 |
| ARCN1 gene, Inflammation, Malnutrition | Altered Intercellular Communication | Although smoking is an important trigger of COPD, other factors such as chronic inflammation and malnutrition are known to influence its development. | 21880073 |
| Celiac Disease, Inflammation, Malnutrition, ARCN1 gene | Altered Intercellular Communication | Because coeliac disease (CD) is characterized both by dysregulated inflammation and malnutrition, the possibility of an association between CD and COPD was investigated. | 21880073 |
| Inflammation, Hypertensive (finding) | Altered Intercellular Communication | Our 3-month study in nondiabetic hypertensive patients showed a decrease in biomarkers of IR and chronic systemic inflammation with the PIO monotherapy and the PIRA combination only, which may help to explain some findings in other cardiovascular outcome trials. | 21880242 |
| HD Term Type, Inflammation, Endotoxemia | Altered Intercellular Communication | Subclinical endotoxemia could contribute to increased inflammation and mortality in hemodialysis (HD) patients. | 21880509 |
| Inflammation, Neoplasms | Altered Intercellular Communication | Inflammation may result in oxidative stress and contribute to promotion and progression of tumors, including BCC. | 21880580 |
| Inflammation, Fibrosis Assessment | Altered Intercellular Communication | Pleiotrophin triggers inflammation and increased peritoneal permeability leading to peritoneal fibrosis. | 21881556 |
| Inflammation, Fibrosis Assessment | Altered Intercellular Communication | Thus, an upregulation of pleiotrophin appears to play a role in fibrosis and inflammation during peritoneal injury. | 21881556 |
| allergic inflammation, Immunity, Innate, Influenza | Altered Intercellular Communication | Remarkably, HDM hyporesponsiveness was overcome when exposure occurred concurrently with an acute influenza infection; young mice now displayed robust allergen-specific immunity, allergic inflammation, and lung remodeling. | 21881572 |
| Have Autoimmune or Inflammatory Condition, Primary malignant neoplasm | Altered Intercellular Communication | Inhibitory substrates of the proteasomes represent promising approaches to control autoimmune inflammations and induction of apoptosis in cancer cells. | 21881828 |
| Inflammation, Ischemia | Altered Intercellular Communication | Misfolding of Notch3 is linked to endoplasmic reticulum stress and increased reactive oxygen species, which may result in dysfunction of endothelial cells, inflammation and ischemia. | 21881852 |
| Refractory anemias, Inflammation, Degenerative polyarthritis | Altered Intercellular Communication | RA patients with multiple-joint inflammation may be less physically active than osteoarthritis patients, resulting in a lower demand on the prosthesis, and these patients may, indeed, be good candidates for all-polyethylene tibial TKA. | 21881885 |
| Inflammation, Mesentery | Altered Intercellular Communication | Our aim was to report the multidetector-row computed tomography (MDCT) findings of sclerosing mesenteritis, which is a rare disease characterized by chronic nonspecific inflammation of mesenteric adipose tissue. | 21882092 |
| Eye pain, Blurred vision, Vitreous opacities, Inflammation | Altered Intercellular Communication | Within two days after injection, blurred vision without ocular pain, anterior chamber inflammation, and vitreous opacity were developed in 6 of the eyes of 6 patients. | 21882588 |
| Inflammation | Altered Intercellular Communication | The composite summary score of inflammation was strongly associated with mortality, with the highest risk estimated for individuals with all three inflammatory markers above the median. | 21883115 |
| Inflammation | Altered Intercellular Communication | In this study, we aimed to histologically characterize FPLD2-associated lipomatosis and study the expression of genes and proteins involved in cell cycle control, mitochondrial function, inflammation and adipogenesis. | 21883346 |
| Trachoma , Inflammation | Altered Intercellular Communication | The overall prevalence of active trachoma (trachomatous inflammation follicular and or trachomatous inflammation intense) was 59% in 1975 and in 2007 was significantly lower at 23% (P<0.001). | 21883776 |
| Inflammation, GDC AJCC Clinical Stage Terminology | Altered Intercellular Communication | Increased inflammation as measured by CRP was not consistently detected despite the identification of an ACS precipitant. | 21883780 |
| Communicable Diseases, GDC AJCC Clinical Stage Terminology | Altered Intercellular Communication | Infection, inflammatory conditions, moderate-heavy exercise and potentially fast food consumption appear to precipitate high-risk ACS. | 21883780 |
| Adenocarcinoma of prostate, Prostatic Intraepithelial Neoplasias, Acute and chronic inflammation | Altered Intercellular Communication | In total, 27 of 40 (68%) patients were found to have adenocarcinoma of the prostate, two patients (5.0%) had atypical small acinar proliferation, one had high-grade prostatic intraepithelial neoplasia (2.5%), four (10%) had chronic active inflammation and six (15%) had benign histology. | 21883818 |
| ARCN1 gene, Inflammation, Chronic Obstructive Airway Disease | Altered Intercellular Communication | Systemic inflammation is a major factor influencing the outcome and quality of patient with chronic obstructive pulmonary disease (COPD) and acute exacerbations (AECOPD). | 21883889 |
| Tumor necrosis, Inflammation, Septic Shock | Altered Intercellular Communication | We have previously reported elevated levels of angiopoietin-2 in patients with septic shock, and have investigated tumor necrosis factor (TNF)-related and weak inducer of apoptosis (TWEAK), which mediates both angiogenesis and inflammation, in those patients. | 21884467 |
| Inflammation, Fibrosis Assessment, Myxoid degeneration, osteoclast activating factor | Altered Intercellular Communication | The level of high-sensitivity C-reactive protein, fibrosis, inflammation, myxoid degeneration, and ubiquitin-aggregates in the atria did not differ between patients with and without POAF. | 21885071 |
| Inflammation, Edema | Altered Intercellular Communication | Instead, the two deeper layers decreased in proliferation rate, maintained vessels density unchanged, were cleared of chronic inflammation and oedema and underwent progression towards stable tissue. | 21885358 |
| Inflammation | Altered Intercellular Communication | Indeed, while most research has focused on induction of superficial granulation tissue by NPT, deeper layers appear to be also affected, with relieving of chronic inflammation and tissue stabilisation. | 21885358 |
| Inflammation | Altered Intercellular Communication | This neutrophilic inflammation of the dermis has been well described in relation to other inflammatory illnesses (i.e. | 21885476 |
| Synovitis, Edema of bone marrow, Erosion of bone, Orchitis, Tenosynovitis | Altered Intercellular Communication | MR images were scored according to PsAMRIS (for synovitis, tenosynovitis, periarticular inflammation, bone marrow edema, bone erosion, and bone proliferation) under standardized conditions, in unknown chronological order. | 21885513 |
| Synovitis, Orchitis, Edema, Tenosynovitis | Altered Intercellular Communication | The interobserver reliability of PsAMRIS was high for synovitis, tenosynovitis, periarticular inflammation, and bone edema status and change scores (interobserver ICC 0.87-0.97). | 21885513 |
| Superficial ulcer, Synovitis, Edema of bone marrow, Orchitis, Tenosynovitis | Altered Intercellular Communication | PsAMRIS sensitivity to change was moderate for synovitis, tenosynovitis, and periarticular inflammation (SRM 0.5-0.8), while poor (SRM 0.1-0.3) for bone marrow edema, erosion, and bone proliferation. | 21885513 |
| PROS1 gene, Inflammation | Altered Intercellular Communication | Measures of inflammation were sensitive to change, implying that PsAMRIS may be a valuable tool for monitoring change in inflammation during PsA clinical trials. | 21885513 |
| Inflammation, Chronic Obstructive Airway Disease | Altered Intercellular Communication | Telomere dysfunction causes sustained inflammation in chronic obstructive pulmonary disease. | 21885626 |
| ARCN1 gene, Inflammation, Chronic Obstructive Airway Disease | Altered Intercellular Communication | Chronic obstructive pulmonary disease (COPD) is associated with chronic inflammation of unknown pathogenesis. | 21885626 |
| ARCN1 gene, Inflammation | Altered Intercellular Communication | To investigate whether telomere dysfunction and senescence of pulmonary vascular endothelial cells (P-ECs) induce inflammation in COPD. | 21885626 |
| ARCN1 gene, Pneumonitis | Altered Intercellular Communication | Telomere dysfunction and premature P-EC senescence are major processes perpetuating lung inflammation in COPD. | 21885626 |
| Acute abdominal pain, Diverticulum | Altered Intercellular Communication | Inflammation of solitary caecal diverticula:a rare aetiology of acute abdominal pain [corrected]. | 21887576 |
| Gastrointestinal inflammation | Altered Intercellular Communication | Enterotoxin-producing staphylococci cause intestinal inflammation by a combination of direct epithelial cytopathy and superantigen-mediated T-cell activation. | 21887731 |
| Epithelial Damage, Inflammatory disease of mucous membrane | Altered Intercellular Communication | Intestinal biopsies from the patients showed marked epithelial damage with mucosal inflammation. | 21887731 |
| Inflammation | Altered Intercellular Communication | Finally, after treatment, a residual inflammation still persisted that might contribute to the observed erythroid disturbances. | 21888450 |
| Inflammation | Altered Intercellular Communication | Microscopic examination of the specimen revealed submucosal and deeply seated intra-muscular and mural heterotopic pancreatic tissue, comprised of both ductal and acinar structures, surrounded by exuberant acute and chronic inflammation. | 21888463 |
| Inflammation, Diabetes Mellitus, Non-Insulin-Dependent | Altered Intercellular Communication | Air pollution may promote type 2 diabetes by increasing adipose inflammation and insulin resistance. | 21888674 |
| Inflammation, Atherosclerosis | Altered Intercellular Communication | Previously, MBTPS1 and PCSK9 have been shown to regulate cholesterol metabolism and LDL receptor recycling, whereas FURIN and PCSK5 have been suggested to inactivate lipases and regulate inflammation in atherosclerosis. | 21889147 |
| Inflammation, Prostatic Diseases | Altered Intercellular Communication | The sensibility of both NF-kB and PSA to inflammation allowed confirming the relationship between these two molecules and its involvement in prostatic diseases progression (inflammatory and neoplasic). | 21889270 |
| Inflammation | Altered Intercellular Communication | Inflammation may play a role in mediating these associations. | 21889359 |
| Inflammation | Altered Intercellular Communication | Increases in inflammation between 2000 and 2006 were associated with long but not short sleep duration in 2006 for several markers. | 21889359 |
| Hyperintensity of cerebral white matter on MRI | Altered Intercellular Communication | Volume of white matter hyperintensities in healthy adults: contribution of age, vascular risk factors, and inflammation-related genetic variants. | 21889590 |
| Inflammation, White matter | Altered Intercellular Communication | Vascular risk and inflammation, which increase with age, may contribute to white matter deterioration and proliferation of WMH. | 21889590 |
| Inflammation | Altered Intercellular Communication | We investigated whether circulating biomarkers and genetic variants associated with elevated vascular risk and inflammation are associated with WMH volume in healthy adults (144 volunteers, 44-77 years of age). | 21889590 |
| nervous system disorder, Inflammation, Congenital Abnormality | Altered Intercellular Communication | Thus, in healthy adults, who are free of neurological and vascular disease, genetic variants that promote inflammation and elevated levels of vascular risk biomarkers can contribute to brain abnormalities. | 21889590 |
| Refractory anemias, Inflammation | Altered Intercellular Communication | IL-6 is a key mediator of inflammation in RA. | 21889771 |
| ARCN1 gene, Inflammation | Altered Intercellular Communication | Dietary intake of polyunsaturated fatty acids, including omega-3 and omega-6, could modulate chronic obstructive pulmonary disease (COPD) persistent inflammation. | 21889886 |
| Inflammation | Altered Intercellular Communication | Ultraviolet (UV) radiation induced inflammation plays an important role in the aging of human skin. | 21889965 |
| Inflammation, Reperfusion Injury | Altered Intercellular Communication | Oxidative stress due to ischemia/reperfusion injury increases systemic inflammation and impairs immune defenses. | 21890323 |
| Inflammation | Altered Intercellular Communication | Our data emphasize the high burden of disease, the persistence of inflammation and the existence of clinical possible phenotypes population sharing common features with published cohorts. | 21890336 |
| Barrett Esophagus, Primary malignant neoplasm | Altered Intercellular Communication | The findings of the present study provide evidence of ectopic AID expression in Barrett's oesophagus and Barrett's oesophageal adenocarcinoma, a cancer that develops under chronic inflammatory conditions. | 21890457 |
| Inflammation, Cardiovascular Diseases, Cyclophosphamide/Vincristine/Dacarbazine Regimen, Congestive heart failure, Chronic heart failure | Altered Intercellular Communication | Low-grade inflammation has been associated with cardiovascular disease (CVD) and chronic heart failure (CHF). | 21890535 |
| Inflammation, Interstitial inflammation, Fibrosis Assessment, Interstitial Fibrosis Assessment, Hypertension, CTCAE | Altered Intercellular Communication | Hypertension at presentation, fibrointimal proliferation of arterial vessels, interstitial fibrosis and interstitial inflammation were shown to be associated with >=50% increase of plasma creatinine level from baseline in univariate analysis (P<0.05 for hypertension and fibrointimal proliferation; P<0.01 for interstitial fibrosis and inflammation). | 21891776 |
| Communicable Diseases, Inflammation, Herpes, Neuronal loss in central nervous system | Altered Intercellular Communication | In fact, Nectin-2 (NC-2); apolipoprotein E (APOE); glycoprotein carcinoembryonic antigen related cell adhesion molecule-16 (CEACAM-16); B-cell lymphoma-3 (Bcl-3); translocase of outer mitochondrial membrane 40 homolog (T0MM-40); complement receptor-1 (CR-l); APOJ or clusterin and C-type lectin domain A family-16 member (CLEC-16A); Phosphatidyl inositol- binding clathrin assembly protein gene (PICALM); ATP-bonding cassette, sub family A, member 7 (ABCA7); membrane spanning A4 (MSA4); CD2 associated protein (CD2AP); cluster of differentiation 33 (CD33); and ephrin receptor A1 (EPHA1) result in a genetic signature that might affect individual brain susceptibility to infection by the herpes virus family during aging, leading to neuronal loss, inflammation, and amyloid deposition. | 21891868 |
| Tumor necrosis, Nerve Degeneration | Altered Intercellular Communication | It presents the evidence that dyotic endocrine signals modulate the expression of tumor necrosis factor (TNF) and related cytokines, and that these cytokines are a functionally important downstream link mediating neurodegeneration and dysfunction. | 21891866 |
| Granulomatous inflammation, Skin lesion | Altered Intercellular Communication | A biopsy specimen from the skin lesion revealed granulomatous inflammation with hyphae. | 21891986 |
| Pneumonitis | Altered Intercellular Communication | High mobility group box-1 (HMGB-1) is an important pro-inflammatory mediator that contributes to acute lung inflammation. | 21893977 |
| Communicable Diseases, Inflammation, Malignant Neoplasms, Disturbance | Altered Intercellular Communication | C-reactive protein (CRP), serum amyloid A (SAA), interleukin-6 (IL-6), a1-antitrypsin (a1AT), a1-acid glycoprotein (a1AG) and ceruloplasmin (CP) are acute inflammatory biomarkers that increase in various conditions including infection, inflammation, malignancy and tissue disturbance. | 21894431 |
| Inflammation | Altered Intercellular Communication | To compare joint inflammation assessment using subjective grading of power Doppler ultrasonography (PDUS) and contrast-enhanced ultrasonography (CEUS) versus computer-aided objective CEUS quantification. | 21894599 |
| Sleep-Disordered Breathing, Inflammation | Altered Intercellular Communication | Relationship between sleep-disordered breathing and markers of systemic inflammation in women from the general population. | 21895822 |
| Sleep-Disordered Breathing, Inflammation, Obesity | Altered Intercellular Communication | Also, for women from the general population there is an independent correlation between SDB and inflammation, even after adjusting for obesity. | 21895822 |
| Inflammation, Sleep Apnea, Obstructive, Hypoxia | Altered Intercellular Communication | The results indicate that intermittent hypoxia, and not the AHI, is related to systemic inflammation seen in OSAS. | 21895822 |
| ARCN1 gene, Inflammation, Chronic Obstructive Airway Disease | Altered Intercellular Communication | Inflammation, both local and systemic, is a hallmark of chronic obstructive pulmonary disease (COPD). | 21896197 |
| ARCN1 gene | Altered Intercellular Communication | Our results indicate that systemic neutrophil responses in COPD patients are caused by a unique but subtle interplay between multiple inflammatory signals. | 21896197 |
| Inflammation, Cortical Dysplasia, Fleck corneal dystrophy | Altered Intercellular Communication | She underwent a right hemispherotomy, and histological examination showed signs of inflammation and features of focal cortical dysplasia (FCD). | 21896424 |
| Hepatitis C | Altered Intercellular Communication | Association of hepatitis C virus infection and malnutrition-inflammation complex syndrome in maintenance hemodialysis patients. | 21896499 |
| Communicable Diseases, Hepatitis C | Altered Intercellular Communication | Patients undergoing maintenance hemodialysis (MHD) have a significantly higher prevalence of hepatitis C virus (HCV) infection and malnutrition-inflammation complex syndrome (MICS). | 21896499 |
| Conjunctival scar, Corneal Opacity, Conjunctivitis | Altered Intercellular Communication | Entropion was more severe among those with a low BMI, those who were female, those aged less than 50 years, and those with moderate to severe conjunctival inflammation, central corneal opacity, and severe conjunctival scarring. | 21896855 |
| Inflammation, Blood Clot, Aortic Aneurysm, Abdominal, Glucocorticoid deficiency with achalasia, Atherosclerotic lesion | Altered Intercellular Communication | Abdominal aortic aneurysms (AAAs) are characterized by presence of high proteolytic activity, atherosclerotic lesions, extensive transmural inflammation and the presence of variably sized and shaped intraluminal thrombus (ILT). | 21897000 |
| APP gene, Inflammation, Blood Clot | Altered Intercellular Communication | Association of higher plasma levels of MMP-9 and CRP with thin ILT may be related to two phenomena: thin thrombi convey more elastolysis-stimulating factors from blood to the AAA wall and thin thrombi convey more factors involved in proteolysis and inflammation from AAA wall to blood. | 21897000 |
| Inflammation | Altered Intercellular Communication | There was no difference in plasma citrulline concentrations among those with confirmed inflammation by imaging or endoscopy (confirmed, 26.2+-11.8; negative, 28.0+-10.0; independent t test P=0.583). | 21897281 |
| hearing impairment, Inflammation, Atrophic, Communicable Diseases | Altered Intercellular Communication | This first reported otopathologic case of SS with hearing loss showed atrophy and degeneration involving the apical halves of the cochlear duct without inflammation or infection. | 21897318 |
| Inflammation | Altered Intercellular Communication | A newly identified cytokine, IL-33, appears to be an important pro-inflammatory cytokine promoting tissue inflammation. | 21898270 |
| ARCN1 gene, Inflammation, Psychiatric, Neurocirculatory Asthenia | Altered Intercellular Communication | There is growing awareness of systemic inflammation and cardiovascular, neurologic, psychiatric, and endocrine comorbidities associated with COPD. | 21898277 |
| Epiglottitis, Inflammation | Altered Intercellular Communication | Acute supraglottitis in adults seems to be a different entity than epiglottitis in children, and inflammation does not usually exclusively involve the epiglottis. | 21898436 |
| Inflammation | Altered Intercellular Communication | Chitinases and chitinase-like proteins play a role in Th2-type inflammation. | 21899483 |
| Inflammation, Chronic sinusitis, Craniosynostosis | Altered Intercellular Communication | Chronic rhinosinusitis (CRS) is a heterogeneous disease characterized by local inflammation of the upper airways and sinuses and is frequently divided into polypoid CRS (CRSwNP) and nonpolypoid CRS (CRSsNP). | 21899560 |
| Inflammation, Craniosynostosis | Altered Intercellular Communication | However, the mechanism of inflammation in CRS has still not been fully elucidated. | 21899560 |
| Inflammation, Craniosynostosis | Altered Intercellular Communication | Overproduction of IL-32 may be involved in the pathogenesis of CRS, although the role of IL-32 in the inflammation in CRSsNP and CRSwNP may be different. | 21899560 |
| Necrotizing granulomatous inflammation, Aggregation | Altered Intercellular Communication | Biopsy of the mass showed sarcoidal type granulomatous inflammation with nodular aggregations of non-necrotizing epithelioid histiocytes in the subcutis. | 21899592 |
| Tumor necrosis, Rheumatoid Arthritis, Psoriasis | Altered Intercellular Communication | Biologic response modifiers targeting tumor necrosis factor alpha (TNFa) are effective treatments of chronic inflammatory conditions such as rheumatoid arthritis and psoriasis. | 21899592 |
| Inflammation | Altered Intercellular Communication | While exercise acts to combat inflammation and aging, the ability to exercise may itself be compromised by inflammation and inflammation's impact on muscle recovery and joint inflammation. | 21899733 |
| Inflammation | Altered Intercellular Communication | While exercise acts to combat inflammation and aging, the ability to exercise may itself be compromised by inflammation and inflammation's impact on muscle recovery and joint inflammation. | 21899733 |
| Autoimmune Diseases, Inflammation | Altered Intercellular Communication | In this discovery phase, significant differences were found for 21 serum proteins implicated in inflammation, oxidation, metabolic regulation, and autoimmunity. | 21900154 |
| Inflammation, Renal Cell Carcinoma | Altered Intercellular Communication | Collectively, our results show that TAMs, often present in RCCs, display enhanced 15-LOX2 activity that contributes to RCC-related inflammation, immunosuppression, and malignant progression. | 21900394 |
| Refractory Cytopenia of Childhood, Inflammation, Neoplasms | Altered Intercellular Communication | We propose that manipulating LOX-dependent arachidonic acid metabolism in the tumor microenvironment could offer new strategies to block cancer-related inflammation and immune escape in patients with RCC. | 21900394 |
| Uveitis | Altered Intercellular Communication | Clinical and imaging characteristics for the four patients include absence of intraocular inflammation, late staining of lesions on fluorescein angiography, and hypofluorescence of lesions on indocyanine green. | 21900853 |
| Inflammation, Obesity | Altered Intercellular Communication | Inflammation associated with obesity: relationship with blood and bone marrow endothelial cells. | 21901025 |
| Inflammation, Thrombosis, Stasis, Heart Failure, Systolic | Altered Intercellular Communication | Thrombosis within the vascular system in relation with inflammation and stasis might be associated with poor prognosis in patients with systolic heart failure (HF). | 21901368 |
| Barrett Esophagus, Inflammation, Esophageal injury | Altered Intercellular Communication | The etiology of this complex disease has been attributed to a variety of factors, including an excess of iron (resulting in increased tumourigenesis), oesophageal injury and inflammation (due in part to Barrett's oesophagus and smoking among others). | 21901748 |
| Gastrointestinal inflammation | Altered Intercellular Communication | Intestinal commensal flora seems to be a requisite for both human and experimental intestinal inflammation. | 21902690 |
| Inflammation | Altered Intercellular Communication | The pathogenesis of BP is controversial and is believed to be caused by inflammation of the facial nerve at the geniculate ganglion. | 21903566 |
| Inflammation, Corneal edema | Altered Intercellular Communication | Examination showed corneal edema, inflammation, and secondary angle closure. | 21904171 |
| Autoimmune Diseases, Inflammation | Altered Intercellular Communication | Interleukin (IL)-17 producing cells play key roles in chronic inflammation and autoimmunity. | 21904631 |
| Adenocarcinoma of prostate, prostatitis | Altered Intercellular Communication | Little is known about the relevance of IL-17 producing cells at sites of prostate tissue inflammation and/or prostate adenocarcinoma. | 21904631 |
| Inflammation, Musculoskeletal torsion, function | Altered Intercellular Communication | These findings suggested auto-amputation of the ovary either by inflammation or torsion. | 21904862 |
| Refractory anemias, Tumor necrosis, Inflammation, Vascular System Injuries | Altered Intercellular Communication | Tumor necrosis factor a (TNFa) is the major mediator of inflammation in RA, related to vascular injury by targeting VE-cadherin, an endothelium-specific adhesion molecule of vital importance for endothelium integrity and angiogenesis. | 21905018 |
| Inflammation | Altered Intercellular Communication | If mBMD loss is driven by inflammation, we expect to find mBMD gain in patients who are in remission. | 21905248 |
| Inflammation | Altered Intercellular Communication | This suggests that mBMD loss is driven by inflammation. | 21905248 |
| Degenerative polyarthritis, Osteoarthritis, Knee, Myositis | Altered Intercellular Communication | Patients with knee osteoarthritis (OA) are characterized by increased muscle inflammation and altered gait. | 21905256 |
| Myositis | Altered Intercellular Communication | Identification of the cellular and molecular mechanisms associated with muscle inflammation is important to better understand the underlying mechanism responsible for altered gait and function in patients with knee OA. | 21905256 |
| Sepsis, Inflammation | Altered Intercellular Communication | C-reactive protein (CRP) is synthesized in the liver in response to inflammation, and CRP is a widely used marker of sepsis. | 21905978 |
| Tendinitis, Arthritis, Enthesopathy | Altered Intercellular Communication | Poor correlation was found between conventional clinical examination and US in cases with joint inflammation, tendonitis and, more particularly, those cases with enthesopathy. | 21906427 |
| palladium, Inflammation, Carotid Atherosclerosis | Altered Intercellular Communication | Our findings suggest that elevated plasma EN-RAGE and decreased sRAGE level could play a crucial role in systemic inflammation and carotid atherosclerosis in PD patients. | 21906738 |
| Inflammation, Chronic Kidney Diseases, Obesity | Altered Intercellular Communication | Systemic inflammation is a hallmark of chronic kidney disease (CKD) and obesity represents a major risk factor for CKD. | 21906921 |
| Inflammation, Non-alcoholic Fatty Liver Disease | Altered Intercellular Communication | Increased lipid peroxidation and inflammation are major factors in the pathogenesis of nonalcoholic fatty liver disease (NAFLD). | 21907687 |
| Hepatic inflammation, Myeloid Leukemia, Chronic | Altered Intercellular Communication | A lipoxidation product that could play a role in the induction of hepatic inflammation is N(e)-(carboxymethyl)lysine (CML). | 21907687 |
| Steatohepatitis, Myeloid Leukemia, Chronic, Hepatic inflammation | Altered Intercellular Communication | CML accumulation was significantly associated with the grade of hepatic steatosis, the grade of hepatic inflammation, and gene expression levels of inflammatory markers PAI-1, IL-8, and CRP. | 21907687 |
| Inflammation, Carcinoma of lung, Breast Carcinoma | Altered Intercellular Communication | We compared plasma protein profiles of four mouse models of lung cancer with profiles of models of pancreatic, ovarian, colon, prostate, and breast cancer and two models of inflammation. | 21907921 |
| Inflammation, Hyperparathyroidism | Altered Intercellular Communication | Impact of cholecalciferol treatment on biomarkers of inflammation and myocardial structure in hemodialysis patients without hyperparathyroidism. | 21908203 |
| Inflammation, Cardiac dysfunction, Electrocardiogram: left ventricle hypertrophy (finding) | Altered Intercellular Communication | Additionally, we observed a reduction in important surrogate markers of cardiovascular risk, namely systemic inflammation and left ventricular hypertrophy, suggesting an anti-inflammatory action and possibly an improvement of cardiac dysfunction. | 21908203 |
| Kidney Failure, Chronic, Inflammation | Altered Intercellular Communication | Effects of alpha-lipoic acid supplementation on inflammation, oxidative stress, and serum lipid profile levels in patients with end-stage renal disease on hemodialysis. | 21908204 |
| Fever, CTCAE, Neoplasms, Meningitis, Intervertebral Disk Displacement, Musculoskeletal Pain, Cervical spondylosis, Spinal Diseases | Altered Intercellular Communication | Patients were initially diagnosed with meningitis (n=4), fever of unknown origin (n=2), cervical spondylosis (n=2), polymyalgia rheumatica (n=1), upper respiratory tract inflammation (n=1), metastatic spinal tumor (n=1), cervical spondylotic myelopathy (n=1), and cervical disc herniation (n=1). | 21909038 |
| Inflammation, Mitochondria | Altered Intercellular Communication | The primary triggers for motor neuron degeneration are unknown but inflammation, oxidative stress and mitochondrial defects have been identified as potential contributing factors. | 21909419 |
| Neoplasm Metastasis, Gastrointestinal inflammation, Neoplasms | Altered Intercellular Communication | SMAD7 regulates gastrointestinal inflammation by inhibiting transforming growth factor-b (TGFB), which can act as both a tumor suppressor and a promoter of metastasis. | 21910156 |
| Inflammation, Temporomandibular Joint, Neoplasms, Traumatic injury, Hernia | Altered Intercellular Communication | Neoplasm, trauma or inflammation in this area can result in displacement of the temporomandibular joint into the ear canal; however, spontaneous herniation is rare. | 21910955 |
| ARCN1 gene, Chronic Obstructive Airway Disease, Airway structure | Altered Intercellular Communication | Asthma and chronic obstructive pulmonary disease (COPD) display features of overlap in airway physiology and airway inflammation. | 21912093 |
| Airway structure, ARCN1 gene, Asthma | Altered Intercellular Communication | To explore the relationship of airway inflammation and cytokine and chemokine expression in asthma and COPD. | 21912093 |
| Airway structure, neutrophilic | Altered Intercellular Communication | In neutrophilic and eosinophilic airway inflammation, TNFa, TNFRI, TNFRII, IL-6, IL-8 and IL-5 could differentiate between these phenotypes. | 21912093 |
| Inflammation, F8 wt Allele | Altered Intercellular Communication | Circulating markers of inflammation may be useful in gauging prognosis in patients with AHF. | 21912122 |
| vascular inflammations, Endothelial dysfunction | Altered Intercellular Communication | In addition to its cholesterol-lowering effect, the ability of simvastatin to ameliorate endothelial dysfunction through increasing NO bioavailability and through suppression of oxidative stress and vascular inflammation and its ability to enhance the effect of ramipril on these parameters may play a pivotal role in these effects. | 21913974 |
| Inflammation, Liver carcinoma, FAM126A gene | Altered Intercellular Communication | Increasing evidence correlates the presence of systemic inflammation with poor survival in patients with hepatocellular carcinoma (HCC). | 21913982 |
| Inflammation, Steroid-sensitive nephrotic syndrome, Cerebral dysfunction | Altered Intercellular Communication | Cerebral amyloid angiopathy-related inflammation presenting with steroid-responsive higher brain dysfunction: case report and review of the literature. | 21914214 |
| Cerebral Amyloid Angiopathy, Inflammation | Altered Intercellular Communication | Histological pathology disclosed b-amyloid in the blood vessels and perivascular inflammation, which highlights the diagnosis of cerebral amyloid angiopathy (CAA)-related inflammation. | 21914214 |
| Cerebral dysfunction | Altered Intercellular Communication | Here we report a patient with CAA-related inflammation who showed higher brain dysfunction that improved with steroid therapy. | 21914214 |
| Crohn Disease, Granulomatous inflammation | Altered Intercellular Communication | Renal involvement in Crohn's disease: granulomatous inflammation in the form of mass lesion. | 21915060 |
| Renal mass | Altered Intercellular Communication | From now on, differential diagnostics of renal mass lesions in CD should include the tumor-like, Crohn's-type granulomatous inflammation as direct kidney manifestation of the disease. | 21915060 |
| Inflammation, Multiple Chronic Conditions | Altered Intercellular Communication | Several studies have linked dietary patterns to insulin sensitivity and systemic inflammation, which affect risk of multiple chronic diseases. | 21915138 |
| Inflammation | Altered Intercellular Communication | A dietary pattern high in low-fat dairy products, fruit, whole grains, poultry, fish and vegetables may be associated with greater insulin sensitivity and lower systemic inflammation in older adults. | 21915138 |
| ARCN1 gene, Pneumonitis | Altered Intercellular Communication | Thus our results suggest that chitinase-related genes may play an important role in establishing pulmonary inflammation and emphysematous changes in smokers and COPD patients. | 21915293 |
| Inflammation, Muscle damage | Altered Intercellular Communication | Comparison of minimally invasive direct anterior versus posterior total hip arthroplasty based on inflammation and muscle damage markers. | 21915544 |
| Muscle damage, Inflammation, Soft Tissue Injuries | Altered Intercellular Communication | We prospectively analyzed biochemical markers of muscle damage and inflammation in patients treated with minimally invasive total hip arthroplasty with an anterior or posterior approach to provide objective evidence of the local soft-tissue injury at the time of arthroplasty. | 21915544 |
| Inflammation, Muscle damage | Altered Intercellular Communication | Independent predictors of elevation in levels of markers of inflammation and muscle damage were determined with use of multivariate logistic regression analysis. | 21915544 |
| Inflammation | Altered Intercellular Communication | The levels of the markers of inflammation were slightly decreased in the direct-anterior-approach group as compared with those in the posterior-approach group. | 21915544 |
| Inflammation, Sleep Apnea, Obstructive, Ischemic stroke | Altered Intercellular Communication | Obstructive sleep apnea and biomarkers of inflammation in ischemic stroke. | 21916851 |
| Inflammation, Thyroid associated opthalmopathies | Altered Intercellular Communication | Excessive orbital fibroblast (OF) proliferation and extracellular matrix production, as well as inflammation resulting in the expansion and remodeling of orbital tissue, are characteristic of Graves ophthalmopathy (GO). | 21917865 |
| Hypoglycemia | Altered Intercellular Communication | Day 2 hypoglycemia counterregulatory hormonal response and glucose turnover [(3-(3)H)-glucose] as indicators of recovery from hypoglycemia. | 21917871 |
| Cessation of life, Inflammation, Abnormality of mitochondrial metabolism | Altered Intercellular Communication | Upregulated pathways included death receptor-mediated caspase cascade, mitochondrial dysfunction, endoplasmic reticulum stress, calpains leading to apoptotic cell death, NF-kB and JAK/STAT pathways, and inflammasome-assembly mediating inflammation. | 21917936 |
| Communicable Diseases, Inflammation | Altered Intercellular Communication | Thus, T(reg) might contribute to the chronic infection and systemic spread of T. whipplei in CWD but in contrast prevent mucosal barrier defect by reducing local inflammation. | 21918190 |
| Micropenis, Cryptorchidism | Altered Intercellular Communication | Clinically it is characterized by low serum concentrations of testosterone and inadequate low levels of luteinizing hormone and follicle-stimulating hormone as well as incomplete sexual maturation, lack of secondary sexual features (facial and body hair growth, deepening of the voice), micropenis and sometimes even cryptorchidism. | 21918848 |
| Sense of smell impaired, Osteoporosis, Cryptorchidism, Infertility, Micropenis, Anemia, Erectile dysfunction | Altered Intercellular Communication | A 19-year-old man presented to our male infertility clinic with delayed sexual maturation, eunuchoid habitus, micropenis, cryptorchidism, erectile dysfunction and absence of ejaculation, anemia and osteoporosis as well as low serum concentrations of luteinizing hormone, follicle-stimulating hormone and testosterone in combination with hyposmia. | 21918848 |
| Cerebrovascular Disorders, Inflammation, Atherosclerosis | Altered Intercellular Communication | Inflammation plays a central role in the pathogenesis of atherosclerosis but no randomized studies have evaluated anti-inflammatory therapy in patients with acute coronary or cerebrovascular disease. | 21918905 |
| Inflammation, Acute Coronary Syndrome, Ischemic stroke | Altered Intercellular Communication | In conclusion, our pilot study provided no evidence that colchicine 1 mg daily for 30 days compared with placebo suppresses inflammation in patients with acute coronary syndrome or acute ischemic stroke. | 21918905 |
| Sarcopenia | Altered Intercellular Communication | The loss of muscle mass and sarcopenia: non hormonal intervention. | 21920428 |
| Inflammation, Edema | Altered Intercellular Communication | The presence of tissue edema was strongly associated with the level of clinical inflammation. | 21920608 |
| Inflammation | Altered Intercellular Communication | Chronic local inflammation is considered to underlie painful symptomatology. | 21920667 |
| Hyperleucinemia, Inflammation, Hypertension, CTCAE, Overweight | Altered Intercellular Communication | Hyperleptinemia is associated with hypertension, systemic inflammation and insulin resistance in overweight but not in normal weight men. | 21920718 |
| Communicable Diseases, Inflammation, glycation | Altered Intercellular Communication | The receptor for advanced glycation end-products (RAGE) is a pattern-recognition receptor involved in the host response to injury, infection and inflammation. | 21920897 |
| ARCN1 gene, Inflammation, Asthma, Chronic Obstructive Airway Disease | Altered Intercellular Communication | We determined whether airway and systemic levels of sRAGE and the RAGE ligands HMGB1 (high-mobility group box-1) and serum amyloid A (SAA) are related to neutrophilic inflammation in asthma and chronic obstructive pulmonary disease (COPD). | 21920897 |
| ARCN1 gene, Asthma | Altered Intercellular Communication | Neutrophilic airway inflammation in asthma and COPD is associated with reduced sRAGE. | 21920897 |
| Alzheimers Disease", Ototoxicity, Data types - Address | Altered Intercellular Communication | Glutamate (Glu) is the most abundant excitatory neurotransmitter in the central nervous system (CNS) and is involved in the pathophysiology of Alzheimer's disease (AD) in which there is an increased excitotoxicity. | 21921084 |
| Refractory anemias, Inflammation, Arthritis | Altered Intercellular Communication | The high frequency of Foxp3+ T cells in pSpA might contribute to the spontaneous resolution and remitting course of arthritis in pSpA as compared to the more persistent joint inflammation in RA. | 21921098 |
| Inflammation, Necrosis, Fracture, Hypertrophy, Hyperplasia | Altered Intercellular Communication | HE staining showed: shrinkage, necrosis, and irregular arrange of the articular chondrocytes, extracellular matrix fracture, hypertrophy and hyperplasia synovium, infiltration of lymphoid and mononuclear cells and proliferation of many small blood vessels in the experimental group; regular arrangement of the articular chondrocytes, the homogeneously staining matrix, and synovial tissue without chronic inflammation and significant proliferation in the normal control group. | 21923032 |
| Inflammation, Arthritis, Periarticular calcification | Altered Intercellular Communication | Arthritis is defined by inflammation, cartilage and bone destruction/formation and articular calcifications. | 21923476 |
| Inflammation, Arthritis | Altered Intercellular Communication | Our objectives were to evaluate ucMGP levels in synovial fluid (SF) in arthritis patients and to investigate the relationship between local and circulating ucMGP and their association with age and inflammation. | 21923476 |
| Inflammation | Altered Intercellular Communication | Transmural histopathological scoring of acute inflammation (AIS) was performed at all locations (score 0-13). | 21924572 |
| Crohn Disease, Inflammation | Altered Intercellular Communication | The MRI activity index was applied to 26 Crohn's patients (mean age 32, range 13-69 years, 15 male) and correlated to terminal ileal biopsy scores of acute inflammation ("eAIS" score 1-6). | 21924572 |
| Inflammation | Altered Intercellular Communication | The model achieved a sensitivity of 0.81 (95% CI 0.54-0.96), specificity of 0.70 (0.35-0.93) and AUC 0.77 for predicting acute inflammation (eAIS >=2). | 21924572 |
| Inflammation, Chronic heart failure | Altered Intercellular Communication | Systemic inflammation and cell activation reflects morbidity in chronic heart failure. | 21924921 |
| Inflammation, Heart failure | Altered Intercellular Communication | Immune activation and inflammation play critical roles in the development of heart failure (HF). | 21925559 |
| Inflammation, Diabetes Mellitus, Non-Insulin-Dependent | Altered Intercellular Communication | To investigate the effects of inflammation on perfusion regulation and brain volumes in type 2 diabetes. | 21926285 |
| Symptoms, Inflammation, Arteritis | Altered Intercellular Communication | After the re-introduction of the IFN beta-1a, the patient had a gradual worsening of the arteritis, with claudication symptoms in the left arm and increased inflammation markers. | 21928043 |
| Inflammation, Carcinogenesis | Altered Intercellular Communication | The angiotensin I-converting enzyme (ACE) is involved in cell proliferation, angiogenesis, inflammation, and tissue remodeling, all of which could play a role in carcinogenesis. | 21928698 |
| Inflammation, Leukemic Infiltration, Chronic Lymphocytic Leukemia, Chronic Lymphocytic Leukemia/Small Lymphocytic Lymphoma, Lymphoplasmacytic Infiltrate | Altered Intercellular Communication | In cases with both CLL/SLL and inflammatory infiltrates, it is unknown whether the CLL infiltrate represents a nonspecific "passenger effect" secondary to ongoing inflammation or pathologic leukemic pulmonary infiltration (LPI). | 21929283 |
| Inflammation, Acute inflammation | Altered Intercellular Communication | LPI was found in 2 of 21 cases (9.5%) with acute inflammation, 0 of 10 cases of chronic inflammation and in 7 of 18 cases (38.8%) without any pathologic findings of acute or chronic inflammation (p = 0.01). | 21929283 |
| Inflammation, Infiltration, Chronic Lymphocytic Leukemia | Altered Intercellular Communication | These results demonstrate that LPI identified in biopsies with concurrent inflammation is uncommon, and that most inflammatory infiltrates in patients with CLL do not cause "passenger effect" CLL infiltration. | 21929283 |
| Amenorrhea | Altered Intercellular Communication | The condition usually first becomes apparent in adolescence with delayed puberty and primary amenorrhea due to the gonads have no hormonal or reproductive potential. | 21929773 |
| Inflammation, Atrial Fibrillation by ECG Finding | Altered Intercellular Communication | Accumulative evidence suggested that oxidative stress and inflammation were involved in the pathogenesis of atrial fibrillation (AF). | 21930315 |
| Inflammation | Altered Intercellular Communication | The increased protective capacity of the Tyr(402) Factor H variant allows better and more efficient clearance and removal of cellular debris and reduces inflammation and pathology. | 21930971 |
| Hyperglycemia | Altered Intercellular Communication | The present findings indicate that pathways regulating glucose uptake in skeletal muscle may be involved in the development of inflammation-associated hyperglycemia. | 21931634 |
| Inflammation, Diabetes Mellitus, Non-Insulin-Dependent | Altered Intercellular Communication | Patients with type 2 diabetes exhibit changes in these pathways, which may ultimately render such patients more prone to develop dysregulated glucose disposal in the context of systemic inflammation. | 21931634 |
| Gingivitis | Altered Intercellular Communication | These cytokines have been reported to correlate with gingival inflammation and periodontal status. | 21932007 |
| Inflammation, Nerve Degeneration | Altered Intercellular Communication | Inflammation accompanied by severe oxidative stress plays a vital role in the orchestration and progression of neurodegeneration prevalent in chronic and acute central nervous system pathologies as well as in aging. | 21932365 |
| Interstitial Fibrosis Assessment, Interstitial inflammation, Tubular atrophy | Altered Intercellular Communication | Cox proportional hazard analysis showed that the glomerular classes were not significant variables, while interstitial fibrosis, tubular atrophy and interstitial inflammation were independent variables associated with renal end-point (HR: 3.36 (95% confidence interval: 1.21-9.32), 4.74 (1.26-17.91)). | 21933307 |
| Inflammation, Cervical Disc Degenerative Disorder | Altered Intercellular Communication | The degeneration of cervical PLL may be related to inflammation. | 21933591 |
| Carotid Atherosclerosis | Altered Intercellular Communication | Imaging intraplaque inflammation in carotid atherosclerosis with 11C-PK11195 positron emission tomography/computed tomography. | 21933781 |
| Diabetes Mellitus, Non-Insulin-Dependent, Vascular Diseases, Inflammation, Endothelial dysfunction | Altered Intercellular Communication | Although perturbations of haemostatic markers have been shown to be associated with macrovascular disease in patients with type 2 diabetes, it is unclear whether these are primarily due to endothelial dysfunction or a result of inflammation. | 21934489 |
| Diabetes Mellitus, Non-Insulin-Dependent, Inflammation, Endothelial dysfunction | Altered Intercellular Communication | The present study was undertaken to elucidate whether elevated levels of factor VIII (FVIII) and von Willebrand factor (vWF) in women with type 2 diabetes represent endothelial dysfunction, inflammation or an alternate mechanism. | 21934489 |
| Inflammation, Endothelium | Altered Intercellular Communication | It also appears that this is not mediated by inflammation or endothelial injury and is likely to be due to an alternate mechanism. | 21934489 |
| Keratopathy, Uveitis | Altered Intercellular Communication | All the eyes with band-shaped keratopathy showed recurrent and chronic intraocular inflammation. | 21934492 |
| Keratopathy, Uveomeningoencephalitic Syndrome, Intraocular inflammation | Altered Intercellular Communication | Band-shaped keratopathy is a relatively uncommon complication in VKH syndrome and mostly occurs in relatively younger patients with a long course of chronic intraocular inflammation. | 21934492 |
| Inflammation, Fever, CTCAE | Altered Intercellular Communication | We report the case of an 82-year-old man with aortic prosthesis inflammation in whom fluorine-18 fluorodeoxyglucose (FDG) positron emission tomography/computed tomography has been useful in the detection of the cause of fever of unknown origin. | 21934523 |
| Inflammation, Gout | Altered Intercellular Communication | Gout can lead to inflammation and damage to cartilage, bone, bursa, tendons, heart, or kidneys. | 21934587 |
| Inflammation, Hyperuricemia, Gout | Altered Intercellular Communication | Patients with gout will have many years of asymptomatic hyperuricemia followed by episodes of acute gouty inflammation and asymptomatic periods. | 21934587 |
| Refractory anemias, Inflammation | Altered Intercellular Communication | Conclusively, IL-33 is involved in the pathogenesis of RA and may reflect the degree of inflammation in patients with RA. | 21935266 |
| Inflammation, Diabetes Mellitus | Altered Intercellular Communication | Diabetes mellitus is associated with enhanced inflammation within AS valves, measured by CRP expression, which may contribute to faster AS progression. | 21935671 |
| Inflammation | Altered Intercellular Communication | Free radicals and redox signalling in T-cells during chronic inflammation and ageing. | 21936801 |
| Inflammation | Altered Intercellular Communication | During chronic inflammation and ageing, the increase in oxidative stress in both intracellular and extracellular compartments is likely to influence local cell functions. | 21936801 |
| Burning sensation, Neurogenic Inflammation, Hyperalgesia | Altered Intercellular Communication | Lingual burning in patients with glossopyrosis is consistent with hyperalgesia and neurogenic inflammation observed in patients and animals with magnesium deficiency and in magnesium deficient tissues. | 21937022 |
| Inflammation, Diabetes Mellitus | Altered Intercellular Communication | Chronic inflammation contributes to insulin resistance and type 2 diabetes mellitus (T2DM). | 21938543 |
| Cataract, Intraocular inflammation, Uveitis | Altered Intercellular Communication | The results indicate that uveitis is not a formal contraindication to primary IOL implantation in the management of pediatric cataract surgery in cases with full control of intraocular inflammation. | 21940141 |
| Intestinal metaplasia, Inflammation, Gland | Altered Intercellular Communication | Using the updated Sydney System, histological parameters including activity, chronic inflammation, glandular atrophy and intestinal metaplasia were graded. | 21940353 |
| Hyalinosis, Systemic, Inflammation | Altered Intercellular Communication | Some clinicians think that HFS is a type of inflammation limited to the hands and feet and can be prevented with a COX-2 inhibitor (celecoxib). | 21940785 |
| Inflammation, Thrombosis | Altered Intercellular Communication | Thrombosis of the sac is thought to induce perianeurysmal brain inflammation, but such phenomena have never been studied in flow-diverter devices. | 21940808 |
| Inflammation, Vasogenic Edema | Altered Intercellular Communication | MR imaging revealed signs highly suggestive of perianeurysmal inflammation with vasogenic edema and blood-brain barrier breakdown. | 21940808 |
| ACSM3 gene, Inflammation, Subarachnoid Hemorrhage | Altered Intercellular Communication | Subarachnoid hemorrhage (SAH) pathophysiology involves neurovascular proteolysis and inflammation. | 21940962 |
| ACSM3 gene, Inflammation | Altered Intercellular Communication | Because pGSN is known to inhibit inflammatory mediators, these findings suggest that MMPs may reduce pGSN and exacerbate inflammation after SAH. | 21940962 |
| Inflammatory abnormality of the eye | Altered Intercellular Communication | These histopathologic findings provide evidence that TB penetrates the ocular surface, induces regression of OSN, and possibly moderates ocular inflammation. | 21941176 |
| Inflammation, cervical cancer, Cervical Intraepithelial Neoplasia | Altered Intercellular Communication | Of the 409 ASC-US, 42.1% showed inflammation; 50.9% had CIN 1, 6.1% had CIN 2, and three cases had CIN 3, one of which was cervical cancer. | 21941964 |
| Airway structure, Asthma | Altered Intercellular Communication | Association of airway inflammation with asthma control level evaluated by the asthma control test. | 21942275 |
| Airway structure, Asthma | Altered Intercellular Communication | The association between airway inflammation and asthma control level is not clear at present. | 21942275 |
| Airway structure | Altered Intercellular Communication | We also evaluated the association between the scores for each ACT question item and eosinophilic or neutrophilic airway inflammation. | 21942275 |
| Inflammation | Altered Intercellular Communication | Asthma control level evaluated by the ACT was not associated with airway eosinophilic or neutrophilic inflammation. | 21942275 |
| Inflammation | Altered Intercellular Communication | Considering that inflammation and oxidative stress are involved in HF evolution, we investigated lipoprotein-associated phospholipase A2 (LpPLA2), an enzyme involved in these pathophysiologic processes in relation to EF. | 21942556 |
| vascular inflammations | Altered Intercellular Communication | Confirming its role as a marker of vascular inflammation, LpPLA2 seems to be a biomarker constantly correlated with HF, regardless of etiology. | 21942556 |
| Inflammation, Periodontal Diseases, Cardiovascular Diseases | Altered Intercellular Communication | Periodontal disease (inflammation of the tissues surrounding teeth) is also widespread, and may contribute to the risk of cardiovascular diseases via pathogenic inflammatory pathways. | 21943132 |
| ARCN1 gene, Inflammation, Chronic Obstructive Airway Disease | Altered Intercellular Communication | Chronic obstructive pulmonary disease (COPD) is associated with systemic inflammation. | 21943856 |
| ARCN1 gene, Inflammation, Atherosclerosis | Altered Intercellular Communication | These findings suggest that systemic inflammation may play a potential role in preclinical atherosclerosis in COPD. | 21943856 |
| Nasal Polyps, Eosinophilic disorder, Craniosynostosis, Nail-Patella Syndrome, Chronic sinusitis | Altered Intercellular Communication | Chronic rhinosinusitis with nasal polyps (CRSwNP) is associated with T(H)2-dominant inflammation, including eosinophilia, which is in contrast to chronic rhinosinusitis (CRS) without nasal polyps (NPs). | 21943944 |
| Inflammation | Altered Intercellular Communication | Overproduction of CCL18 might contribute to the pathogenesis of CRSwNP through its known activities, which include recruitment of lymphocytes and dendritic cells, activation of fibroblasts, and initiation of local inflammation. | 21943944 |
| Inflammation, Conventional (Clear Cell) Renal Cell Carcinoma | Altered Intercellular Communication | Many signaling pathways are implicated in clear cell renal carcinoma development, including the inflammation pathway. | 21944129 |
| Cessation of life, Inflammation, Conventional (Clear Cell) Renal Cell Carcinoma | Altered Intercellular Communication | Results suggest that inflammation gene expression may be significant prognostic biomarkers for the risk of recurrence (GADD45G) and death (CARD9, CIITA and NCF2) in patients with clear cell renal carcinoma. | 21944129 |
| Inflammation, Thickened, Blood Clot, Pannus, Tears body substance, Calcinosis | Altered Intercellular Communication | Cusp tears and thickening, calcification (at radiography), pannus formation, inflammation, and thrombus deposition were noted. | 21944438 |
| Inflammation | Altered Intercellular Communication | Extensive retroperitoneal inflammation extending into the paravisceral aorta was encountered. | 21944481 |
| Inflammation, Leucocytic infiltrate, Fibrosis Assessment, Aneurysm, Ruptured, Vessel perforation, Phlebitis, Infiltration | Altered Intercellular Communication | Histology demonstrated vessel wall rupture, adventitial fibrosis and inflammatory cell infiltration, obliterative phlebitis, lymphoid follicles, perineural inflammation, and immunoglobulin G4 (IgG4) plasma cell infiltration, consistent with a contained ruptured aneurysm associated with IgG4 periaortitis. | 21944481 |
| APP gene, Inflammation, Aortic Aneurysm, Abdominal | Altered Intercellular Communication | The purpose of this study was to identify local differences in inflammation and tissue degradation within the circumference of the abdominal aortic aneurysm (AAA). | 21944916 |
| HD Term Type, Inflammation | Altered Intercellular Communication | IL-21 is decreased in HD patients and is not affected by gender, age, inflammation, the vintage of HD, type of medication and type of used dialysis membrane. | 21945025 |
| Inflammatory Bowel Diseases, Inflammation | Altered Intercellular Communication | TH1 and TH17 interactions in untreated inflamed mucosa of inflammatory bowel disease, and their potential to mediate the inflammation. | 21945121 |
| Inflammation, Ulcerative Colitis | Altered Intercellular Communication | Recently, a TH17 lineage has been introduced, but their role in the inflammation of CD and UC is not fully understood. | 21945121 |
| Inflammation, Cerebral Infarction | Altered Intercellular Communication | To investigate the effect of anti-Helicobacter pylori on the inflammation mediators and prognosis in patients with acute cerebral infarction. | 21946199 |
| Communicable Diseases, Inflammation | Altered Intercellular Communication | C-reactive protein (CRP) is a nonspecific parameter for infection and inflammation but might be employed as a trigger for diagnosis. | 21947022 |
| Communicable Diseases, Chemotherapy-Induced Febrile Neutropenia, Inflammation | Altered Intercellular Communication | (18)F-FDG PET/CT scanning during chemotherapy-induced febrile neutropenia and increased CRP is able to detect localized foci of infection and inflammation despite the absence of circulating neutrophils. | 21947022 |
| Inflammation | Altered Intercellular Communication | Associated chronic inflammation had resulted in the huge keloids. | 21947163 |
| Inflammatory abnormality of the eye | Altered Intercellular Communication | In addition, fungal DNA was also not detected in patients without ocular inflammation (controls). | 21947326 |
| Inflammation, Hypertriglyceridemia | Altered Intercellular Communication | Our data suggests that a hypertriglyceridemic state is associated with hs-CRP irrespective of BMI, LDL-C, and HDL-C, indicating that hs-CRP might represent chronic inflammation induced by hypertriglyceridemia in Japanese men with normal glucose tolerance. | 21948178 |
| Inflammatory abnormality of the eye | Altered Intercellular Communication | Although the costimulatory molecule OX40 promotes T-cell function and expansion, it is unclear whether OX40 is implicated in ocular inflammation. | 21948545 |
| Optimism, Inflammation, Endothelial dysfunction | Altered Intercellular Communication | Optimism in relation to inflammation and endothelial dysfunction in older men: the VA Normative Aging Study. | 21949417 |
| Inflammation, Endothelial dysfunction, Coronary heart disease | Altered Intercellular Communication | Higher overall optimism scores were associated with lower levels of inflammation and endothelial dysfunction in older men free of coronary heart disease. | 21949417 |
| Non-alcoholic Fatty Liver Disease, Hepatitis | Altered Intercellular Communication | In severe NAFLD patients, FGF21 concentration might decrease due to liver inflammation or injury. | 21949781 |
| Catapres, Inflammation, Pain Distress Question | Altered Intercellular Communication | She was taking Arthrotec (a combination of diclofenac and misoprostol - for pain and inflammation), Fosamax Plus D (alendronate with vitamin D3 - recently prescribed because of low bone density), and Catapres (clonidine - for menopausal symptoms). | 21951026 |
| Inflammation, "Alzheimers Disease | Altered Intercellular Communication | Amyloid plaques dissociate pentameric to monomeric C-reactive protein: a novel pathomechanism driving cortical inflammation in Alzheimer's disease? | 21951392 |
| Inflammation, "Alzheimers Disease | Altered Intercellular Communication | Beta-amyloid (Ab) plaques and local inflammation are central to the pathogenesis of Alzheimer's disease. | 21951392 |
| Inflammation, "Alzheimers Disease | Altered Intercellular Communication | We hypothesized that Ab plaques induce the dissociation of pCRP to individual monomers (mCRP), which possess strong pro-inflammatory properties not shared with pCRP and localizing inflammation to Alzheimer's plaques. | 21951392 |
| Alzheimers Disease", Inflammation | Altered Intercellular Communication | The existence of mCRP but not pCRP in the brains of Alzheimer's disease patients strongly indicates that this newly described biological effect of Ab plaques is relevant in Alzheimer pathobiology; potentially localizing and amplifying inflammation via the strong pro-inflammatory effects of locally generated mCRP. | 21951392 |
| Refractory anemias, Inflammation, Rheumatoid Arthritis | Altered Intercellular Communication | Anti-cyclic citrullinated peptide antibodies (ACPA) seem to be produced locally at the site of joints inflammation in the first stage of rheumatoid arthritis (RA). | 21952975 |
| Inflammation, AAVS1 gene, Vasculitis, CTCAE | Altered Intercellular Communication | To identify biomarkers that distinguish between active antineutrophil cytoplasmic antibody (ANCA)-associated vasculitis (AAV) and remission in a manner superior or complementary to established markers of systemic inflammation. | 21953143 |
| Inflammation | Altered Intercellular Communication | This study was undertaken to investigate the significance of residual inflammation in remission in relation to radiographic progression. | 21953215 |
| Inflammation, Arteritis | Altered Intercellular Communication | SVV was defined as inflammation of the small vessels external to the temporal artery adventitia, and VVV was defined as isolated inflammation of temporal artery vasa vasorum. | 21953306 |
| Inflammation, Coronary Artery Disease, Angina Pectoris | Altered Intercellular Communication | Reduced activity of systemic inflammation had a beneficial effect on the course of coronary artery disease (significant decrease in the functional class of stable angina). | 21954641 |
| vascular inflammations, Metabolic Syndrome X | Altered Intercellular Communication | Our data show that patients with the metabolic syndrome given a statin/TZD combination manifest greater reductions in markers of vascular inflammation and oxidant stress, 24-h ambulatory BP and increases in adiponectin as well as improved glycaemic indices. | 21955403 |
| Uveitis | Altered Intercellular Communication | All eyes showed no clinical signs of postoperative intraocular inflammation. | 21955552 |
| Inflammation, Malnutrition, Atherosclerosis | Altered Intercellular Communication | Effects of conventional versus biocompatible peritoneal dialysis solutions on peritoneal and systemic inflammation, malnutrition and atherosclerosis in CAPD patients. | 21955867 |
| Inflammation, Malnutrition, Atherosclerosis | Altered Intercellular Communication | Chronic inflammation, malnutrition and atherosclerosis (MIA syndrome) are important predictors of high mortality in continuous ambulatory peritoneal dialysis (CAPD) patients. | 21955867 |
| Inflammation | Altered Intercellular Communication | All patients underwent echocardiography and B-mode ultrasonography of common carotid arteries together with assessments of nutrition status and parameters of systemic and local inflammation. | 21955867 |
| Inflammation, Glioblastoma Multiforme Pathway | Altered Intercellular Communication | The postoperative therapy and the inflammation might have contributed to the severe change in morphological phenotype of the glioma. | 21955926 |
| Inflammation | Altered Intercellular Communication | Inflammation can affect the ventricles with an unknown mechanism, and QTc may be slightly prolonged as a result in the active phase of AS. | 21955979 |
| Orbital Pseudotumor, Blepharoptosis | Altered Intercellular Communication | Lyme-associated orbital inflammation presenting as painless subacute unilateral ptosis. | 21956017 |
| Lyme Disease, Orbital Pseudotumor | Altered Intercellular Communication | Lyme disease should be included in the differential diagnosis of orbital inflammation, especially in Lyme-endemic areas. | 21956017 |
| Inflammation, Atopy | Altered Intercellular Communication | Pediatric inflammatory vulvitis (PIV) is clinically characterized by itching, soreness and inflammation and can be due to both an infective process and a non-specific irritative process, especially in atopic patients. | 21956267 |
| Hypoestrogenism, Hypothalamic amenorrhea | Altered Intercellular Communication | Functional hypothalamic amenorrhea (FHA) related to hypoestrogenism and hormonal status may influence skeletal homeostasis and body composition. | 21957879 |
| Arterial Stiffness, Inflammation, Diabetes Mellitus, Non-Insulin-Dependent | Altered Intercellular Communication | The association of specific metabolites of lipid metabolism with markers of oxidative stress, inflammation and arterial stiffness in men with newly diagnosed type 2 diabetes. | 21958081 |
| Arterial Stiffness, Inflammation, Diabetes Mellitus, Non-Insulin-Dependent, Diabetes Mellitus | Altered Intercellular Communication | To determine whether circulating metabolic intermediates are associated with inflammation, oxidative stress and arterial stiffness in men with newly diagnosed type 2 diabetes and investigate the circulating metabolic intermediates that may predict the risk of developing diabetes. | 21958081 |
| Arterial Stiffness, Inflammation, Diabetes Mellitus | Altered Intercellular Communication | Circulating lipid-related intermediate metabolites can be closely associated with inflammation, oxidative stress and arterial stiffness in early diabetes. | 21958081 |
| hearing impairment, Communicable Diseases, Inflammation, Ear Inflammation | Altered Intercellular Communication | Hearing loss was related to otitis (odds ratio [OR], 2.58; 95% confidence interval [CI], 1.66-4.02; p < 0.001) and inversely related to serotype 23 F infection (OR, 0.36; 95% CI, 0.13-0.98; p = 0.025), but not with parameters of disease severity or indicators of cerebrospinal fluid inflammation severity. | 21958295 |
| hearing impairment, Ear Inflammation | Altered Intercellular Communication | Otitis and resulting perilympathic inflammation contribute to meningitis-associated hearing loss. | 21958295 |
| Inflammation | Altered Intercellular Communication | The patient was given high-dose antibiotics due to the secondary inflammation involving the parietal peritoneum. | 21959616 |
| Inflammation, Primary malignant neoplasm, Psychological Distress | Altered Intercellular Communication | The aim of this study was to investigate the potential correlations between nutritional status, systemic inflammation, and psychological distress in cancer patients. | 21959842 |
| Inflammation, Anxiety, CTCAE 3.0, Depression, CTCAE | Altered Intercellular Communication | Mini Nutritional Assessment (MNA) was used for the evaluation of nutritional status, Glasgow Prognostic Score (GPS) for the estimation of systemic inflammation, and Hospital Anxiety and Depression Scale (HADS) for psychological assessment. | 21959842 |
| Inflammation | Altered Intercellular Communication | Probably, central venous catheters (CVCs) contribute to this resistance by inducing inflammation and oxidative stress. | 21960369 |
| Inflammation, Dental Plaque | Altered Intercellular Communication | We hypothesized that microbubbles are retained in areas of plaque inflammation, aiming to examine whether LP-CEUS signal reflects plaque biology. | 21960570 |
| Inflammation, Rupture | Altered Intercellular Communication | LP-CEUS reflects biological features of inflammation and angiogenesis, key features predisposing to plaque rupture. | 21960570 |
| Inflammation, Carotid Atherosclerosis | Altered Intercellular Communication | Further investigation of LP-CEUS as a tissue-specific marker of inflammation for risk stratification of carotid atherosclerosis is warranted. | 21960570 |
| Inflammation | Altered Intercellular Communication | The most common reason for open conversion was severe acute inflammation (38.7%). | 21962732 |
| Inflammation | Altered Intercellular Communication | Older patients have a higher likelihood of conversion with severe acute inflammation being the most common reason for conversion. | 21962732 |
| Inflammation, Aortic Aneurysm | Altered Intercellular Communication | Inflammation is associated with the formation of aortic aneurysm. | 21962843 |
| vascular inflammations, Arterial aneurysm | Altered Intercellular Communication | The Cys-X-Cys chemokine receptor 3 receptor is necessary for vascular inflammation and the formation of arterial aneurysms in mice. | 21962843 |
| Inflammation, Lower Urinary Tract Symptoms | Altered Intercellular Communication | Chronic inflammation has been reported to be associated with the pathogenesis of BPH and lower urinary tract symptoms (LUTS). | 21962879 |
| Inflammation | Altered Intercellular Communication | Chronic inflammation may play a role in the occurrence of residual urgency in BPH patients. | 21962879 |
| Pain Distress Question, Inflammation, Complication Aspects, Ocular Hypertension, Peripheral ulcerative keratitis, Uveitis | Altered Intercellular Communication | Clinical features (pain, scleral inflammation), ocular complications (decrease in vision, anterior uveitis, peripheral ulcerative keratitis, ocular hypertension), and disease associations. | 21963265 |
| Inflammation, Necrotizing Scleritis, Ocular Hypertension, Scleritis, Uveitis | Altered Intercellular Communication | Risk factors for decrease in vision in patients with scleritis included necrotizing scleritis (odds ratio [OR], 6.63; P<0.001), posterior scleritis (OR, 2.33; P = 0.042), degree of scleral inflammation of more than 2+ (range, 0-4+; OR, 3.60; P<0.001), anterior uveitis (OR, 1.78; P = 0.033), ocular hypertension (OR, 3.19; P<0.001), and associated disease (OR, 2.66; P<0.001), mainly infectious (OR, 4.44; P<0.001). | 21963265 |
| Inflammation, Necrotizing Scleritis, Ocular Hypertension, Communicable Diseases, Scleritis, Uveitis | Altered Intercellular Communication | Risk factors for decrease in vision in patients with scleritis include necrotizing scleritis, posterior scleritis, scleral inflammation of more than 2+, anterior uveitis, ocular hypertension, and associated infectious disease. | 21963265 |
| Communicable Diseases, Inflammation | Altered Intercellular Communication | Postoperatively, patients were followed for improvement in Snellen visual acuity, control of inflammation, and development of complications such as infection or uncontrolled intraocular pressure in the eyes. | 21963487 |
| Refractory anemias, Inflammation, Atherosclerosis | Altered Intercellular Communication | These prospective data provide evidence that inflammation is a contributor to the progression of subclinical atherosclerosis in RA and that it is potentially modified favorably by TNF inhibitors and detrimentally by glucocorticoids. | 21965129 |
| Inflammation, Hypertensive (finding), Damage, Obesity | Altered Intercellular Communication | The effect of inflammation on the development of hypertensive end organ damage may be associated with obesity, so that control of obesity may eliminate the inflammatory state in hypertensive patients and also hypertensive end organ damage. | 21966945 |
| Inflammation, osteoclast activating factor | Altered Intercellular Communication | Several factors are linked to postoperative AF (POAF), including advanced age and systemic inflammation. | 21967453 |
| Barrett Esophagus, Inflammation | Altered Intercellular Communication | Use of aspirin was not associated with nondysplastic Barrett's oesophagus when compared with population (OR=1.01, 95% CI 0.71-1.43) or inflammation controls (OR=1.16, 95% CI 0.80-1.68). | 21967506 |
| Autosomal Recessive Disorder, Inflammation, Cognitive disability, Vascular Diseases | Altered Intercellular Communication | Dysmorphic features, cognitive disability, chronic inflammation, and predisposition to vascular disease in two sisters: a new autosomal recessive disorder? | 21968521 |
| Inflammation, Carcinogenesis | Altered Intercellular Communication | Oxidative damage by reactive oxygen species (ROS) plays a major role in skin aging, carcinogenesis and inflammation. | 21968658 |
| Inflammation, Necrosis | Altered Intercellular Communication | However, additional studies are necessary to determine the clinical utility of GTE for decreasing skin cell ROS, necrosis and inflammation. | 21968658 |
| Inflammation | Altered Intercellular Communication | Interleukin-17-positive mast cells contribute to synovial inflammation in spondylarthritis. | 21968742 |
| Inflammation | Altered Intercellular Communication | We therefore undertook the present study to investigate the potential contribution of mast cells to synovial inflammation in SpA. | 21968742 |
| Inflammation | Altered Intercellular Communication | The specific and TNF-independent increase in IL-17-expressing mast cells may contribute to the progression of synovial inflammation in peripheral SpA. | 21968742 |
| Doxorubicin/Thiotepa/Vinblastine, Inflammation, Aortic Aneurysm | Altered Intercellular Communication | Immune response activation solely in the aortic media of TAV patients suggests that inflammation is involved in TAA formation in TAV but not in BAV patients. | 21968790 |
| Inflammation, Sarcopenia | Altered Intercellular Communication | Measures of sarcopenia are associated with lower cognitive functioning in older adults, and for females, this association may be partly due to systemic inflammation. | 21968867 |
| Endothelial dysfunction, Atherosclerosis | Altered Intercellular Communication | Induction of vascular GTP-cyclohydrolase I and endogenous tetrahydrobiopterin synthesis protect against inflammation-induced endothelial dysfunction in human atherosclerosis. | 21969008 |
| Inflammation, Vascular Diseases | Altered Intercellular Communication | We hypothesized that induction of BH4 synthesis might be an endothelial defense mechanism against inflammation in vascular disease states. | 21969008 |
| Inflammation, Salmonella typhi | Altered Intercellular Communication | In Study 1, 20 healthy individuals were randomized to receive Salmonella typhi vaccine (a model of acute inflammation) or placebo in a double-blind study. | 21969008 |
| Inflammation | Altered Intercellular Communication | The ability to increase vascular GCH1 expression and BH4 synthesis in response to inflammation preserves endothelial function in inflammatory states. | 21969008 |
| Endothelial dysfunction | Altered Intercellular Communication | These novel findings identify BH4 as a vascular defense mechanism against inflammation-induced endothelial dysfunction. | 21969008 |
| Myocarditis | Altered Intercellular Communication | Pericardial inflammation may be a marker for reversibility. | 21969014 |
| Pericardial sac structure, Inflammation | Altered Intercellular Communication | Antiinflammatory therapy was associated with a reduction in pericardial and systemic inflammation and LGE pericardial thickness, with resolution of CP physiology and symptoms. | 21969014 |
| Overactive Bladder | Altered Intercellular Communication | Dysregulation of neurotransmitter receptors may contribute to bladder overactivity (OAB) symptoms. | 21969132 |
| Cholangiocarcinoma, Fibrosis Assessment, Intrahepatic bile duct, interstitial | Altered Intercellular Communication | It is speculated that peribiliary gland involvement by superficially spreading bile duct cancer and subsequent obstructive glandular inflammation with fibrosis might cause intrahepatic bile duct strictures even without interstitial cancer invasion. | 21969205 |
| Inflammation | Altered Intercellular Communication | MRI of her thigh muscles revealed serpiginous increased T-2 signals consistent with inflammation and a complex round mass in the left pelvis. | 21969283 |
| Minimal Disseminated Disease, Anhedonia, Depressive disorder | Altered Intercellular Communication | Anhedonia, a core symptom of major depressive disorder (MDD) and highly variable among adolescents with MDD, may involve alterations in the major inhibitory amino acid neurotransmitter system of g-aminobutyric acid (GABA). | 21969419 |
| Minimal Disseminated Disease, Anhedonia | Altered Intercellular Communication | These findings suggest that GABA, the major inhibitory neurotransmitter in the brain, may be implicated in adolescent MDD and, more specifically, in those with anhedonia. | 21969419 |
| Inflammation, Loading Technique | Altered Intercellular Communication | Our results suggest that plasma 24S-OH-Chol levels might be increased in the first stages of LOAD, and this phenomenon might be related with systemic inflammation. | 21970714 |
| Celiac Disease, Inflammation | Altered Intercellular Communication | Children with celiac disease (CD) are at risk for decreased bone mineral density (BMD) because of fat-soluble vitamin malabsorption, inflammation and/or under-nutrition. | 21970944 |
| Inflammation, Metabolic Syndrome X | Altered Intercellular Communication | Chemerin is an adipokine associated with metabolic syndrome, systemic inflammation and innate immune system. | 21971116 |
| Alzheimers Disease", millicurie, Inflammation | Altered Intercellular Communication | In a total of 205 people with MCI, 77 of whom subsequently converted to Alzheimer's disease, we find biochemical markers of inflammation to be better predictors of conversion than APOE genotype or clinical measures (Area under the curve (AUC) 0.65, 0.62, 0.59 respectively). | 21971479 |
| Refractory anemias, Rheumatoid Arthritis | Altered Intercellular Communication | As rheumatoid arthritis (RA) occurs more often in women than in men, it has been suggested that reproductive hormones may play an important role in the pathogenesis. | 21972241 |
| Inflammation, Thrombosis, Atrial Fibrillation by ECG Finding | Altered Intercellular Communication | Intracardiac expression of markers of endothelial damage/dysfunction, inflammation, thrombosis, and tissue remodeling, and the development of postoperative atrial fibrillation. | 21972893 |
| Atrial Fibrillation, Inflammation | Altered Intercellular Communication | LAA and RAA tissue was excised during CABG in 100 patients free of AF and inflammation. | 21972893 |
| Inflammation, Aortic Aneurysm, Abdominal | Altered Intercellular Communication | Changes in thrombin generation, fibrinolysis, platelet and endothelial cell activity, and inflammation following endovascular abdominal aortic aneurysm repair. | 21975058 |
| APP gene, Aortic Aneurysm, Abdominal | Altered Intercellular Communication | Abdominal aortic aneurysm (AAA) is a chronic inflammatory condition associated with a prothrombotic, hypofibrinolytic diathesis that may increase the risk of cardiovascular events. | 21975058 |
| Inflammation, Colorectal Carcinoma | Altered Intercellular Communication | Prognosis of patients with colorectal cancer (CRC) is associated with systemic inflammation, and anti-inflammatory drugs can reduce both CRC incidence and mortality. | 21976545 |
| Toxic effect, Inflammatory disease of mucous membrane | Altered Intercellular Communication | Dose-limiting toxicities (stomatitis/mucosal inflammation events) were reported in the 800 mg (n = 1), 1200 mg (n = 1), and 1600 mg (n = 2) groups. | 21976672 |
| Inflammation, Leukopenia | Altered Intercellular Communication | The most commonly reported grade >= 3 events were febrile neutropenia (n = 24) and stomatitis/mucosal inflammation (n = 16). | 21976672 |
| Chronic Kidney Diseases | Altered Intercellular Communication | Ang-2 levels are associated with systemic markers/mediators of micro-inflammation in CKD patients. | 21976741 |
| Inflammation, Hypertension, CTCAE, Obesity | Altered Intercellular Communication | Lipocalin-2 is recently recognized as a biomarker of obesity and inflammation, which are both risk factors for hypertension. | 21978028 |
| Delirium, Inflammation | Altered Intercellular Communication | The purpose of this study was to investigate whether increased cerebral inflammation with microglial, astrocyte, and cytokine activation exists in patients with delirium compared to nondelirious patients. | 21978081 |
| Gastrointestinal inflammation | Altered Intercellular Communication | Intestinal inflammation was strongly associated with these elevations as they were absent during remission and significantly reduced with anti-inflammatory treatment. | 21978578 |
| Inflammation, Burn injury, Edema | Altered Intercellular Communication | Oxidative stress and inflammation generate edema in burns. | 21978796 |
| Inflammation, Metabolic Syndrome X, MS gene | Altered Intercellular Communication | No information is available on its presence in human adipocytes and its potential involvement in the chronic inflammation associated with metabolic syndrome (MS). | 21978920 |
| Inflammation, Atherosclerosis | Altered Intercellular Communication | Analysis of the leukocyte transriptome, in particular the Finkel-Biskis-Jinkins Osteosarcoma (c-Fos) gene, which has a prominent role in inflammation, provides new insights into atherosclerosis mechanisms. | 21978922 |
| Inflammation, Tooth Loss, Obesity | Altered Intercellular Communication | Obesity induced inflammation may promote periodontal tissue destruction and bone resorption inducing tooth loss. | 21979390 |
| Inflammation, Intracranial Aneurysm | Altered Intercellular Communication | Chronic inflammation is postulated as an important phenomenon in intracranial aneurysm wall pathophysiology. | 21980208 |
| airway disease, Inflammation | Altered Intercellular Communication | Previously, we have shown in other upper and lower airway diseases that immunoglobulin free light chains (FLCs) are increased and may be involved in initiating a local inflammation. | 21980441 |
| Pyelonephritis, Communicable Diseases, Chronic obstruction, Nephrolithiasis, NEXMIF gene | Altered Intercellular Communication | Xanthogranulomatous pyelonephritis (XPN) is a rare inflammatory condition usually secondary to chronic obstruction caused by nephrolithiasis and resulting in infection and irreversible destruction of the renal parenchyma. | 21980741 |
| Inflammation | Altered Intercellular Communication | As a result, the negative feedback regulation loop with miR-146a involving down-regulation of inflammation factors was interrupted in aged mice. | 21981419 |
| Refractory anemias, Rheumatoid Arthritis, Autoimmune Diseases, Inflammation | Altered Intercellular Communication | Rheumatoid arthritis (RA) is a chronic autoimmune disease that causes inflammation and, in many cases, destruction of the joints. | 21981664 |
| Inflammation, Obesity, Atherosclerosis | Altered Intercellular Communication | Given these properties, chemerin may provide an interesting link between obesity, inflammation and atherosclerosis. | 21981776 |
| Inflammation, Primary malignant neoplasm | Altered Intercellular Communication | Chronic low-grade inflammation is a possible risk factor for cancer that may be modifiable with long-term exercise. | 21982875 |
| Inflammation, Acute Coronary Syndrome | Altered Intercellular Communication | Marked systemic inflammation associated with acute coronary syndrome was reduced by 1-month therapy with high dose atorvastatin. | 21983801 |
| Inflammation, Malnutrition, Anemia | Altered Intercellular Communication | In addition, data on age, sex, disability status, comorbidities, anemia control, malnutrition and inflammation, calcium-phosphorus metabolism and hospitalization rate were collected. | 21983989 |
| Inflammation, Endothelial dysfunction | Altered Intercellular Communication | von Willebrand factor and CECs (both P < 0.05) were significantly elevated in EA suggesting endothelial dysfunction and damage but were unrelated to classical laboratory markers of inflammation C-reactive protein, erythrocyte sedimentation rate or IL6. | 21985471 |
| Inflammation, Arthritis | Altered Intercellular Communication | Endothelial damage/dysfunction is present early in the course of inflammatory arthritis but is not directly related to inflammation markers. | 21985471 |
| Inflammation, Chronic Obstructive Airway Disease | Altered Intercellular Communication | : TNF-a mediated inflammation is thought to play a key role in the respiratory and systemic features of Chronic Obstructive Pulmonary Disease. | 21985478 |
| Inflammation | Altered Intercellular Communication | Thickening of the intimal layer of arteries characterized by expression of smooth muscle a-actin (SMaA), collagen deposition, and inflammation is an important pathophysiological change with aging assumed to be mediated by smooth muscle cells migrating from the medial layer. | 21985896 |
| Intraocular inflammation | Altered Intercellular Communication | This was followed by an acute increase in intraocular pressure (IOP) to 60 mm Hg despite open angles, no evidence of intraocular inflammation, and no corticosteroid use. | 21986163 |
| Inflammation, Weight decreased, Non-Small Cell Lung Carcinoma | Altered Intercellular Communication | Baseline insulin-like growth factor-I plasma levels, systemic inflammation, weight loss and clinical outcome in metastatic non-small cell lung cancer patients. | 21986483 |
| Inflammation, Primary malignant neoplasm, Weight decreased | Altered Intercellular Communication | Cancer patients frequently suffer from weight loss and systemic inflammation in the context of advanced disease, which is related to adverse outcome. | 21986483 |
| Inflammation, Non-Small Cell Lung Carcinoma | Altered Intercellular Communication | IGF-I correlates with systemic inflammation and seems to play an independent predictive role in metastatic non-small cell lung cancer. | 21986483 |
| Unknown (origin) (qualifier value), Inflammation | Altered Intercellular Communication | Although previous large-vessel arteritis cannot be absolutely excluded, a diagnosis of idiopathic MAS was made, given the absence of any other clinical signs of inflammation (C-reactive protein <0.5 mg/dl; erythrocyte sedimentation rate 5 mm/h). | 21986626 |
| Inflammation, Primary malignant neoplasm | Altered Intercellular Communication | Systemic inflammation and prediction of chemotherapy outcomes in patients receiving docetaxel for advanced cancer. | 21986674 |
| Inflammation, Vasogenic Edema | Altered Intercellular Communication | Two patients in the 200-mg group showed transient and focal areas of inflammation or vasogenic edema on magnetic resonance imaging scans at sites with the highest level of amyloid reduction. | 21987394 |
| Inflammation | Altered Intercellular Communication | Autophagy is a process of central importance for maintaining cell homeostasis, survival, and the regulation of inflammation. | 21987459 |
| Acute and chronic inflammation | Altered Intercellular Communication | We provide a model of how a dysfunction of the CD susceptibility genes, PTPN2 and/or ATG16L1, may contribute to the onset and perpetuation of chronic intestinal inflammation. | 21987459 |
| palladium, Inflammation, Abnormality of mitochondrial metabolism | Altered Intercellular Communication | The majority of these differentially expressed proteins are known to be involved in processes that have been implicated in the pathogenesis of PD previously, including mitochondrial dysfunction, oxidative stress, protein misfolding, cytoskeleton dysregulation and inflammation. | 21988495 |
| Multiple Organ Failure, Inflammation, Respiratory Distress Syndrome, Adult, Inflammatory, Fracture | Altered Intercellular Communication | Systemic inflammation in response to a femur fracture and the additional fixation is associated with inflammatory complications, such as acute respiratory distress syndrome and multiple organ dysfunction syndrome. | 21988742 |
| Inflammation, Traumatic injury | Altered Intercellular Communication | This study intents to identify C1-esterase inhibitor as a safe and potent anti-inflammatory agent, that is capable of suppressing systemic inflammation in trauma patients. | 21988742 |
| Inflammation | Altered Intercellular Communication | This might facilitate early total care procedures by lowering the risk of inflammation in response to the surgical intervention. | 21988742 |
| Inflammation, Illness Behavior, Fatigue | Altered Intercellular Communication | Prior work has suggested that fatigue may be related to inflammation and its associated sickness behaviors; accordingly, our findings may be tapping into this same physiological substrate. | 21988771 |
| Inflammation | Altered Intercellular Communication | Local inflammation was more frequently noted when catheters were colonized (26.9% [95% CI, 15.2%-38.7%] versus 8.1% [95% CI, 4.2%-11.9%], P = 0.005). | 21989151 |
| Inflammation, Sarcopenia | Altered Intercellular Communication | Chronic inflammation is one of the most important physiologic correlates of the frailty syndrome and high levels of proinflammatory cytokines, related to both aging and increasing adiposity in older individuals are related to an increased risk of mortality, sarcopenia, reduced muscle strength and decreased mobility. | 21989337 |
| Inflammation, Muscle (organ) | Altered Intercellular Communication | The purpose of this narrative review is to inform the physical therapist of the effects of aging and increasing adiposity on chronic inflammation and the association of inflammation with muscle loss, strength, and mobility impairments in older adults; and to review the current evidence to provide clinical recommendations on physical activity and exercise regimes that may mitigate chronic inflammation in older adults. | 21989337 |
| Inflammation | Altered Intercellular Communication | Exercise is a potent preventive intervention strategy and countermeasure for chronic inflammation and adiposity. | 21989337 |
| Inflammation | Altered Intercellular Communication | Exercise can also benefit the frail older individual by combating the negative effects of chronic inflammation and optimally balancing the production of pro and anti-inflammatory cytokines. | 21989337 |
| Inflammation, muscle mass | Altered Intercellular Communication | In addition to providing an anti-inflammatory environment within muscle to mitigate the effects of chronic inflammation, exercise has the added benefit of improving muscle mass and function and decreasing adiposity in older adults. | 21989337 |
| Frailty | Altered Intercellular Communication | Frailty, a predisability condition with links to chronic inflammatory conditions, is estimated to affect 7% of individuals older than 60 years and 40% of people older than 80 years. | 21989337 |
| Degenerative polyarthritis, Inflammation, Vascular Alterations | Altered Intercellular Communication | Besides biomechanical mechanisms, the pathogenesis of osteoarthritis may involve inflammation, vascular alterations and dysregulation of lipid metabolism. | 21989540 |
| Inflammation | Altered Intercellular Communication | Whether this is due to burn-out of inflammation in late disease must be investigated further. | 21989543 |
| vascular inflammations, Optic Neuropathy, Ischemic | Altered Intercellular Communication | Our findings indicate that local expression of PTX3 is a feature of vascular inflammation in GCA; elevated circulating levels of PTX3 identify patients with very recent optic nerve ischemia or a recent diagnosis. | 21989653 |
| Inflammation, Takayasu Arteritis | Altered Intercellular Communication | The assessment of disease activity in Takayasu arteritis (TA) is difficult in clinical situations because clinical symptoms and laboratory parameters do not always reflect the actual inflammation of the arterial wall. | 21989701 |
| Inflammation | Altered Intercellular Communication | The intended delivery of AIS into the inflamed tissue could alleviate tissue destruction taking place during chronic inflammation, as well as facilitate the termination of these processes. | 21990110 |
| Fibrosis Assessment | Altered Intercellular Communication | Bioactive polyglycolic/polylactic acid (PGLA)-coated Matrix detachable coils were reported to incite intra-aneurysmal inflammation and fibrosis. | 21990437 |
| Inflammation, Dental Plaque, Calcinosis | Altered Intercellular Communication | Inflammation and angiogenesis are hypothesized to be important factors contributing to plaque vulnerability, whereas calcification is suggested to confer stability. | 21990578 |
| Inflammation, Dental Plaque, Calcinosis | Altered Intercellular Communication | We provide in vivo evidence that increased plaque metabolism is associated with increased biomarkers of angiogenesis and inflammation, whereas plaque calcification is inversely related to PET and histologic biomarkers of inflammation. | 21990578 |
| Inflammation, Nasal Polyps, Craniosynostosis | Altered Intercellular Communication | The majority of patients with CRS with nasal polyps (CRS with NP) are characterized by predominantly eosinophilic inflammation. | 21991563 |
| Craniosynostosis | Altered Intercellular Communication | However, Asian patients with CRS with NP show characteristics indicative of neutrophilic inflammation. | 21991563 |
| Inflammation, Craniosynostosis | Altered Intercellular Communication | Eosinophilic inflammation was found in 59.6% of patients with CRS with NP. | 21991563 |
| Balanitis | Altered Intercellular Communication | Plasma cell balanitis (PCB), also knows as Zoon balanitis, is a benign asymptomatic but chronic and erosive inflammatory condition of the glans penis and prepuce that generally affects uncircumcised men in later years. | 21992223 |
| Inflammation, Thrombophilia, Corneal Endothelial Cell Loss | Altered Intercellular Communication | Markers of the TF pathway, hypercoagulability, inflammation and endothelial cell damage were measured in plasma. | 21993387 |
| Inflammation, Lupus Erythematosus, Systemic | Altered Intercellular Communication | Changes to the TF pathway were not associated with manifestations of SLE such as inflammation or endothelial cell damage. | 21993387 |
| Acute Lung Injury, Inflammation, Postoperative Complications, Respiratory Distress Syndrome, Adult | Altered Intercellular Communication | The con-tinuous improvement of surgical techniques has led to a decrease in surgical complications, whereas up to 30% of the patients develop postoperative pulmonary complications such as acute lung injury (ALI) or even the more severe acute respiratory distress syndrome (ARDS), which are characterized by an acute inflammation in the lung parenchyma and the airspace. | 21993488 |
| Inflammation, Hypertension, CTCAE | Altered Intercellular Communication | Renal resistive index and low-grade inflammation in patients with essential hypertension. | 21993489 |
| Inflammation, Nephritis, Tubulointerstitial, Hypertension, CTCAE | Altered Intercellular Communication | In essential hypertension low-grade inflammation is associated with tubulo-interstitial damage evaluated by Doppler ultrasonography. | 21993489 |
| Granulomatous inflammation | Altered Intercellular Communication | However, bacteriological confirmation is essential because of the presence of various granulomatous inflammation. | 21994193 |
| Inflammation, Arteriopathic disease | Altered Intercellular Communication | The genotype may have an effect on systemic MMP-8 levels which could not, however, be seen in the arterial disease patients probably as a result of the strong inflammation involved in the disease pathogenesis. | 21994255 |
| Periodontal Diseases, Inflammation, Diabetes Mellitus, Non-Insulin-Dependent | Altered Intercellular Communication | Inflammation associated with periodontal diseases, characterized by elevated pro-inflammatory cytokines, innate immune receptor expression, and cellular infiltrate was exacerbated in patients with T2D. | 21996642 |
| Inflammation, Hyperglycemia | Altered Intercellular Communication | In addition, a feed forward loop regulated by poor glycemic control was associated with a loss of mucosal barrier integrity and accumulation of innate immune receptor ligands resulting in an exacerbation of ongoing inflammation, where RAGE and TLR4 cooperated to induce responses in oral epithelial cells, which were exacerbated by hyperglycemia. | 21996642 |
| Inflammation, Pancreatitis | Altered Intercellular Communication | Acute pancreatitis is a form of inflammation with clinical features ranging from pancreatic inflammation to fatal systemic manifestations. | 21997439 |
| Inflammation, Endosalpingiosis | Altered Intercellular Communication | We propose a model for the development of ovarian and extraovarian low-grade serous proliferations (APST, noninvasive epithelial implants, and endosalpingiosis) that postulates that all of these lesions are derived from PTH, which appears to be induced by chronic inflammation. | 21997682 |
| Pneumonitis | Altered Intercellular Communication | Groups were initially compared for survival and subsequently for markers of pulmonary inflammation, influx of lymphocytes and neutrophils, and expression of PD-1 and its ligand-PD-L1. | 21997806 |
| Autoimmune Diseases, Monoclonal Gammopathy of Undetermined Significance, Infection | Altered Intercellular Communication | A personal history of all infections combined was associated with a significantly increased risk of MM (OR = 1.2; 95% CI, 1.1-1.3), and a personal history of all conditions in the categories infections (OR = 1.6; 95% CI, 1.5-1.7), inflammatory conditions (OR = 1.4; 95% CI, 1.2-1.5), and autoimmune diseases (OR = 2.1; 95% CI, 1.9-2.4) was associated with a significantly increased risk of MGUS. | 21998210 |
| Inflammation, Thrombosis, Tacca leontopetaloides | Altered Intercellular Communication | Though systemic inflammation and thrombosis are associated with TIA, further study may provide insight into TIA pathophysiology and possibly lead to the development of treatments specifically targeted to TIA. | 21998319 |
| Inflammation | Altered Intercellular Communication | These genes were associated with systemic inflammation, platelet activation, and prothrombin activation. | 21998319 |
| Pain Distress Question, Inflammation | Altered Intercellular Communication | Higher pain scores and more inflammation were reported with Nd:YAG laser; however, it was preferred by 29 volunteers (74%). | 21999492 |
| Hyperglycemia, Atherosclerosis, Plaque, Atherosclerotic | Altered Intercellular Communication | Although hyperglycemia is associated with an increased risk of atherosclerotic cardiovascular disease, there are no clinical data to show the preference of any specific oral hypoglycemic agents to prevent atherosclerotic plaque inflammation. | 21999871 |
| Inflammation | Altered Intercellular Communication | Plaque inflammation was measured by blood-normalized standardized uptake value, known as a target-to-background ratio. | 21999871 |
| Inflammation | Altered Intercellular Communication | Multiple stepwise regression analysis revealed that the increase in high-density lipoprotein cholesterol level was independently associated with the attenuation of plaque inflammation. | 21999871 |
| Plaque, Atherosclerotic, diabetic | Altered Intercellular Communication | Pioglitazone may be a promising strategy for the treatment of atherosclerotic plaque inflammation in impaired glucose tolerance or diabetic patients. | 21999871 |
| Inflammation, Diabetes Mellitus, Non-Insulin-Dependent | Altered Intercellular Communication | (Detection of Plaque Inflammation and Visualization of Anti-Inflammatory Effects of Pioglitazone on Plaque Inflammation in Subjects With Impaired Glucose Tolerance and Type 2 Diabetes Mellitus by FDG-PET/CT; NCT00722631). | 21999871 |
| hormone deficiency, Precocious Puberty | Altered Intercellular Communication | This syndrome has only once been associated with growth hormone deficiency and precocious puberty in the same patient. | 22001135 |
| Acromegaly, Diseases of mitral valve | Altered Intercellular Communication | Valvular disease in patients with acromegaly is associated with hormonal activity, and control of growth hormone and insulin-like growth factor I excesses is important in the long-term durability of mitral valve repair. | 22001216 |
| Acromegaly, Diseases of mitral valve | Altered Intercellular Communication | Valvular disease in patients with acromegaly is associated with hormonal activity, and control of growth hormone and insulin-like growth factor I excesses is important in the long-term durability of mitral valve repair. | 22001216 |
| Gastritis | Altered Intercellular Communication | Therefore, a lack of effectiveness in eradication therapy can lead to chronic stomach inflammation and promote cancerogenesis. | 22001987 |
| Mucous Membrane, polyps, Inflammation | Altered Intercellular Communication | The exact pathogenetic mechanism of polyp formation is unclear although it seems possible that the underlying cause is mucosal injury that is vascular in nature rather than being secondary to surface inflammation. | 22002002 |
| Vitritis, Inflammation, Fibrinous | Altered Intercellular Communication | There was a strong anterior segment inflammation with fibrinous exudates and a dense vitritis. | 22003760 |
| Inflammation, Asthma, Common Cold, Herpes Labialis | Altered Intercellular Communication | Five subjects reported five adverse events (secondary herpes labialis recurrences, n = 2; infectious rhinitis, n = 1; application site inflammation, n = 1; bronchial asthma, n = 1). | 22004219 |
| Inflammation | Altered Intercellular Communication | At the site of inflammation, macrophages and neutrophils are present as well as cytokines such as TNF-a and IFN-g. | 22004597 |
| Inflammation, Cervical Intraepithelial Neoplasia | Altered Intercellular Communication | There was not a significant association between the degree of the CIN and the staging of the SCC of the cervix and the degree of inflammation as assessed by the levels of inflammatory markers. | 22004597 |
| Inflammation, Diego blood group system, Dyskeratosis | Altered Intercellular Communication | Periadnexal inflammation was observed in 12 patients (80%) in the DI group vs 37 (84%) in the non-DI group, and basal layer liquefaction with dyskeratosis was seen in 15 patients (100%) in the DI group and in 37 (84%) in the non-DI group. | 22004879 |
| ARCN1 gene, Respiratory physiology, Inflammation | Altered Intercellular Communication | The progressive decline in lung function that occurs in COPD is a result of persistent inflammation of the airways and destruction of the lung parenchyma. | 22005302 |
| ARCN1 gene, Inflammation | Altered Intercellular Communication | Despite the key role of inflammation in the pathogenesis of COPD, treatment with corticosteroids - normally highly effective antiinflammatory drugs - has little therapeutic benefit. | 22005302 |
| Inflammation, Chronic graft-versus-host disease | Altered Intercellular Communication | Clinical laboratory markers of inflammation as determinants of chronic graft-versus-host disease activity and NIH global severity. | 22005783 |
| Stable chronic Graft vs Host Disease, Inflammation | Altered Intercellular Communication | We analyzed clinical markers of inflammation in the sera of patients with established cGVHD and correlated those with definitions of disease activity. | 22005783 |
| Stable chronic Graft vs Host Disease, Inflammation | Altered Intercellular Communication | This study identified common laboratory indicators of inflammation that can serve as markers of cGVHD activity and severity. | 22005783 |
| Inflammation, Primary malignant neoplasm | Altered Intercellular Communication | Fucosylation is a crucial oligosaccharide modification in cancer and inflammation. | 22006099 |
| Inflammation, Laryngopharyngeal Reflux, Hypertrophy of adenoids, Bacterial Infections | Altered Intercellular Communication | Inflammation and enlargement of the adenoids is not likely due to ongoing bacterial infection arising from laryngopharyngeal reflux. | 22006777 |
| Inflammation, Benign prostatic hypertrophy | Altered Intercellular Communication | [The relationship between anaphylatoxin C3a and benign prostatic hyperplasia with inflammation]. | 22007489 |
| Inflammation, Elastosis perforans serpiginosa | Altered Intercellular Communication | C3a levels in EPS of the BPH patients: severe inflammation group > mild inflammation group > normal control group (all P < 0.01). | 22007489 |
| Inflammation, Elastosis perforans serpiginosa | Altered Intercellular Communication | C3a levels in the EPS could be used to determine whether BPH combined inflammation, sensitivity : 0.97, specificity: 0.70. | 22007489 |
| Inflammation, Prostate | Altered Intercellular Communication | C3a is an ideal criteria to diagnose prostatic histological inflammation in BPH patients. | 22007489 |
| Cessation of life, Inflammation, Organ dysfunction syndrome, Communicable Diseases | Altered Intercellular Communication | The most important and common cause of death for the patients with FP is multiple organ dysfunction syndrome, which usually was the consequence of systemic inflammation response syndrome in the early stage, and the severe infection in the later stage, respectively. | 22007499 |
| Inflammation, Aortic Stiffness, Overweight | Altered Intercellular Communication | Serum aldosterone is associated with inflammation and aortic stiffness in normotensive overweight and obese young adults. | 22007645 |
| vascular inflammations | Altered Intercellular Communication | Circulating aldosterone may play an important role in vascular inflammation and aortic stiffening in normotensive overweight and obese adults. | 22007645 |
| Inflammation, Impaired cognition | Altered Intercellular Communication | These findings suggest that inflammation plays an important role in the development and presence of cognitive impairment. | 22008268 |
| Inflammation | Altered Intercellular Communication | Concentration of CSF CXCL10, CXCL11, CXCL12, CXCL13 and serum CXCL10, CXCL13 may be good biomarkers of CNS inflammation caused by TBEV. | 22008312 |
| Granulomatous inflammation, Fibrosis Assessment | Altered Intercellular Communication | In these 21 patients, severity of liver-test abnormalities was significantly associated with extensiveness of granulomatous inflammation (r=0.58, P=0.006) and degree of fibrosis (r=0.64, P=0.002). | 22008629 |
| Inflammation, Anemia, HIV Infections | Altered Intercellular Communication | Anemia, particularly iron deficiency anemia and anemia of inflammation, is highly prevalent among children with HIV infection. | 22009132 |
| Degenerative polyarthritis, Inflammation, Joint swelling | Altered Intercellular Communication | Ultrasound treatment significantly alleviates joint symptoms, relieving joint swelling, increasing joint mobility and reducing inflammation, in osteoarthritis patients. | 22009649 |
| Inflammation, KANTR gene, Obstruction, Traumatic injury, GDC AJCC Clinical Stage Terminology | Altered Intercellular Communication | Among the uncommon causes, such as spasm, obstruction, inflammation or trauma of the coronary arteries, carbon monoxide poisoning could be the cause of ACS. | 22010452 |
| Inflammation, Chronic heart failure | Altered Intercellular Communication | It was showed that cardiac resynchronization therapy had an impact on systemic inflammation and hormonal status in patients with chronic heart failure during short-term observation. | 22010472 |
| Inflammation, Chronic heart failure | Altered Intercellular Communication | It was showed that cardiac resynchronization therapy had an impact on systemic inflammation and hormonal status in patients with chronic heart failure during short-term observation. | 22010472 |
| Inflammation, Obesity | Altered Intercellular Communication | Obesity is a state of chronic low-grade inflammation. | 22011432 |
| Inflammation, Diabetes Mellitus, Atherosclerosis | Altered Intercellular Communication | Chronic low-grade inflammation is associated with the pathophysiology of both type-2 diabetes and atherosclerosis. | 22011432 |
| Inflammation, Obesity | Altered Intercellular Communication | Prevention or reduction of chronic low-grade inflammation may be advantageous in relation to obesity related co-morbidity. | 22011432 |
| Inflammation | Altered Intercellular Communication | Histology indicated absence of inflammation in 50 patients (48%). | 22011584 |
| Diastolic dysfunction, Inflammation, Hypertension, CTCAE, Heart failure | Altered Intercellular Communication | Changing from an ACEi or ARB to losartan/HCTZ is associated with a reduction in BP, improvement in LV relaxation, improvement in heart failure state and attenuation of systemic inflammation with few adverse effects in patients with hypertension and diastolic dysfunction. | 22011686 |
| vascular inflammations, Cyclophosphamide/Vincristine/Dacarbazine Regimen, Cardiovascular Diseases | Altered Intercellular Communication | Few studies are available in human populations investigating involvement of vascular inflammation and oxidative stress-related dysfunctional transformation of high-density lipoprotein (HDL) in establishing cardiovascular disease (CVD) risk. | 22011848 |
| vascular inflammations | Altered Intercellular Communication | In conclusion, TSP-4, a matricellular protein involved in regulating vascular inflammation, plays a role in establishing recurrent coronary risk in post-infarction patients with high levels of HDL-C and CRP. | 22011848 |
| Inflammation, Chronic Kidney Diseases | Altered Intercellular Communication | High dietary fiber intake is associated with decreased inflammation and all-cause mortality in patients with chronic kidney disease. | 22012132 |
| Inflammation, Chronic Kidney Diseases | Altered Intercellular Communication | Chronic kidney disease is considered an inflammatory state and a high fiber intake is associated with decreased inflammation in the general population. | 22012132 |
| Inflammation, Chronic Kidney Diseases, Kidney Diseases | Altered Intercellular Communication | Here, we determined whether fiber intake is associated with decreased inflammation and mortality in chronic kidney disease, and whether kidney disease modifies the associations of fiber intake with inflammation and mortality. | 22012132 |
| Inflammation, Kidney Diseases | Altered Intercellular Communication | The relationship of total fiber with inflammation and mortality differed significantly in those with and without kidney disease. | 22012132 |
| Inflammation, Kidney Diseases | Altered Intercellular Communication | Thus, high dietary total fiber intake is associated with lower risk of inflammation and mortality in kidney disease and these associations are stronger in magnitude in those with kidney disease. | 22012132 |
| Inflammation, Kidney Diseases | Altered Intercellular Communication | Interventional trials are needed to establish the effects of fiber intake on inflammation and mortality in kidney disease. | 22012132 |
| vascular inflammations, Calcinosis | Altered Intercellular Communication | Our results suggest that hemodynamic stress, vascular inflammation and calcification, and matrix remodeling may have a role in the pathogenesis and/or adverse consequences of increased pulse pressure. | 22012208 |
| Neoplasms | Altered Intercellular Communication | It is possible that the pattern of Cxs may contribute to tumor formation and growth, as it may indicate aberrant and/or reduced cell-to-cell communication ability. | 22012769 |
| Inflammation, Metabolic Syndrome X, Coronary heart disease | Altered Intercellular Communication | The relationships between FAM5C SNP (rs10920501) variability and metabolic syndrome and inflammation in women with coronary heart disease. | 22013132 |
| ARCN1 gene, Lung hyperinflation, Inflammation | Altered Intercellular Communication | Dynamic pulmonary hyperinflation and low grade systemic inflammation in stable COPD patients. | 22013730 |
| ARCN1 gene, Inflammation, Chronic Obstructive Airway Disease | Altered Intercellular Communication | It is increasingly recognized that a low grade of systemic inflammation occurs in patients with advanced chronic obstructive pulmonary disease (COPD). | 22013730 |
| ARCN1 gene, Lung hyperinflation, DERMATITIS HERPETIFORMIS, FAMILIAL, Inflammation | Altered Intercellular Communication | The aim of the study was to assess if resting dynamic pulmonary hyperinflation (DH) is linked to the presence of systemic inflammation in COPD. | 22013730 |
| ARCN1 gene, Lung hyperinflation, Inflammation | Altered Intercellular Communication | These results show that the IC reduction is associated with higher serum levels of CRP in stable COPD patients, suggesting a potential role of dynamic pulmonary hyperinflation on development and maintenance of low grade systemic inflammation in COPD. | 22013730 |
| Inflammation, Fibrosis Assessment, Idiopathic Pulmonary Fibrosis | Altered Intercellular Communication | Although mast cells are regarded as important regulators of inflammation and tissue remodelling, their role in cystic fibrosis (CF) and idiopathic pulmonary fibrosis (IPF) has remained less studied. | 22014187 |
| Inflammation, Fibrosis Assessment | Altered Intercellular Communication | In the alveolar parenchyma in lungs from patients with CF, MCTC numbers increased in areas showing cellular inflammation or fibrosis compared to controls. | 22014187 |
| Cerebrovascular Disorders, Inflammation, Impaired cognition | Altered Intercellular Communication | Our findings suggest that inflammation and dysregulation of the fibrynolitic system may be involved in the pathological mechanisms underlying the WM damage seen in cerebrovascular disease and subsequent cognitive impairment. | 22014619 |
| Inflammation, Chronic disease | Altered Intercellular Communication | Epidemiological studies have reported associations between circulating inflammation markers and risk of chronic diseases. | 22015105 |
| Inflammation, Chronic disease, Hereditary Breast and Ovarian Cancer Syndrome | Altered Intercellular Communication | Our findings suggest that risk factors for chronic diseases (age, BMI, menopausal status, parity, NSAID use, family history of breast and ovarian cancer, and smoking) are associated with inflammation markers in healthy women. | 22015105 |
| Herpes Zoster Ophthalmicus, Complication Aspects, Inflammation, Scleritis | Altered Intercellular Communication | Patient characteristics (age, sex); ocular disease characteristics (laterality, type of scleritis, degree of scleral inflammation, ocular complications, delay in presentation, and follow-up period), systemic disease association (associated disease, potentially lethal associated disease); and anti-inflammatory and immunosuppressive medications were studied in patients with scleritis. | 22015381 |
| Inflammation, Complication Aspects | Altered Intercellular Communication | Successful response to treatment with NSAIDs was associated with idiopathic diffuse or nodular scleritis with a low degree of scleral inflammation (<= 2+) (odds ratio [OR] = 2.89, P < 0.001) and with idiopathic diffuse or nodular scleritis without ocular complications (OR = 3.13, P < 0.001). | 22015381 |
| Inflammation, Simian Acquired Immunodeficiency Syndrome | Altered Intercellular Communication | Successful treatment with SAIDs was associated with idiopathic diffuse or nodular scleritis with a high degree of scleral inflammation (>2+) (OR = 4.70, P = 0.001). | 22015381 |
| Inflammation, Complication Aspects | Altered Intercellular Communication | Patients with idiopathic diffuse or nodular scleritis with a low degree of scleral inflammation or without ocular complications may respond to NSAIDs. | 22015381 |
| Inflammation, Simian Acquired Immunodeficiency Syndrome | Altered Intercellular Communication | Patients with idiopathic diffuse or nodular scleritis with a high degree of scleral inflammation may respond to SAIDs. | 22015381 |
| Inflammation | Altered Intercellular Communication | The reverse dipper circadian pattern is associated with inflammation and constitutes an independent predictor of graft outcome. | 22015441 |
| Airway structure, Smooth muscle (tissue), Bronchial Hyperreactivity | Altered Intercellular Communication | Transforming growth factor (TGF) b1 increases pro-inflammatory cytokines and contractile protein expression by human airway smooth muscle (ASM) cells, which could augment airway inflammation and hyperresponsiveness. | 22015454 |
| Inflammation, Traumatic injury, Trichilemmal cyst | Altered Intercellular Communication | Proliferating trichilemmal cysts are rare, slowly growing, lobular masses inherited autosomal dominantly and localized on scalps, and believed to arise due to a complication of a trauma and inflammation, and 5-10% of people are reported to be effected. | 22016280 |
| Inflammation, Impaired cognition, Failure (biologic function), Trauma, Nervous System | Altered Intercellular Communication | The failure of highly active antiretroviral therapy (HAART) to eliminate cognitive dysfunction in HIV may be secondary to persistence of HIV-infected PBMCs which cross the blood-brain barrier, leading to perivascular inflammation and neuronal injury. | 22016479 |
| Inflammation, Weight decreased, Non-Small Cell Lung Carcinoma | Altered Intercellular Communication | The objective of the current study was to assess the value of osteopontin as a marker of weight loss in relation to systemic inflammation in non-small cell lung cancer (NSCLC) patients. | 22017168 |
| Inflammation, Weight decreased, Carcinoma of lung | Altered Intercellular Communication | In addition to being an indicator of systemic inflammation in lung cancer patients, osteopontin may also be an indicator of weight loss. | 22017168 |
| Inflammation, Primary malignant neoplasm | Altered Intercellular Communication | Association between chronic inflammation and cancer is known and chronic inflammation is one of the characteristics of OLP. | 22017396 |
| Inflammation, Primary malignant neoplasm | Altered Intercellular Communication | A protein connected to inflammation and suggested to be involved in cancer development is cyclooxygenase-2 (COX-2) which can be inhibited by microRNA-26b (miR-26b). | 22017396 |
| Inflammation, Pulmonary Dysfunction | Altered Intercellular Communication | We concluded that inflammation has a close relation with pulmonary dysfunction in hemodialysis patients. | 22017533 |
| Inflammation | Altered Intercellular Communication | Inflammation may be a key inciting as well as propagating feature of DP neuropathology. | 22017610 |
| Inflammation, Cardiovascular Diseases | Altered Intercellular Communication | Understanding systemic inflammation, oral hygiene, and cardiovascular disease. | 22017776 |
| Carcinoma of anal margin, Infection | Altered Intercellular Communication | Anal squamous cell carcinoma is rare and seems to be associated with chronic inflammatory conditions, infections and immunosuppression. | 22018257 |
| Inflammation, Primary malignant neoplasm | Altered Intercellular Communication | The neutrophil to lymphocyte ratio (NLR), an index of systemic inflammation, is associated with outcome in several cancer types. | 22018713 |
| Inflammation, Non-Small Cell Lung Carcinoma, BDI - Functional Impairment | Altered Intercellular Communication | Pre-cachexia in patients with stages I-III non-small cell lung cancer: systemic inflammation and functional impairment without activation of skeletal muscle ubiquitin proteasome system. | 22018880 |
| Inflammation, Muscular Atrophy | Altered Intercellular Communication | Preclinical research indicates that systemic inflammation induces cachexia-related muscle wasting through muscular Nuclear Factor-kappa B (NF-kB) signaling and subsequent ubiquitin proteasome system (UPS)-mediated proteolysis. | 22018880 |
| Inflammation, Muscular Atrophy, Cachexia | Altered Intercellular Communication | The absence of muscular NF-kB-dependent inflammatory signaling supports the notion that transition of systemic to local inflammation is required to initiate UPS-dependent muscle wasting characteristic for (experimental) cachexia. | 22018880 |
| Inflammation, Muscular Atrophy, Cachexia | Altered Intercellular Communication | The absence of muscular NF-kB-dependent inflammatory signaling supports the notion that transition of systemic to local inflammation is required to initiate UPS-dependent muscle wasting characteristic for (experimental) cachexia. | 22018880 |
| Inflammation, Blood Vessel, Data types - Address | Altered Intercellular Communication | MPV is an index of platelet activation and may be a potential marker of inflammation to demonstrate the vascular damage in AD. | 22019010 |
| Inflammatory Bowel Diseases, Colitis | Altered Intercellular Communication | Colonic inflammation caused by inflammatory bowel disease, which has been suggested to stimulate endogenous nitrosation, did not influence fecal NOC excretion or fecal water genotoxicity. | 22019696 |
| Inflammation, Thrombosis, Heart, Brain Injuries | Altered Intercellular Communication | We drew blood soon after admission and measured markers of inflammation, thrombosis, cardiac strain, and cerebral damage. | 22020034 |
| Inflammation, Intimal proliferation, Chronic Kidney Diseases, Vascular System Injuries | Altered Intercellular Communication | Inflammation, oxidation and venous neointimal hyperplasia precede vascular injury from AVF creation in CKD patients. | 22020525 |
| Inflammation, Chronic Kidney Diseases | Altered Intercellular Communication | Not only does venous IH pre-exist, but inflammation and oxidation markers are present within veins used for the AVF conduit prior to its creation in CKD patients as early as one year before dialysis is commenced. | 22020525 |
| Multiple polyps, Inflammation, Tissue Adhesions | Altered Intercellular Communication | Disease recurrence and adverse wound healing in the form of inflammation, polyposis, adhesions, and middle turbinate lateralization may induce suboptimal outcomes following sinus surgery. | 22020898 |
| Inflammation, polyps, Tissue Adhesions | Altered Intercellular Communication | Efficacy was assessed by grading inflammation, polyp formation, adhesions, and middle turbinate position. | 22020898 |
| Inflammation, Tissue Adhesions | Altered Intercellular Communication | At 1 month, minimal degrees of inflammation and adhesions were observed, suggesting a positive clinical impact of local steroid delivery without evidence of ocular risk. | 22020898 |
| Inflammation, Mesenteric Venous Thrombosis, Vasculitis, CTCAE | Altered Intercellular Communication | Pathological examination confirmed chronic inflammation and vasculitis of intestinal connective tissue, combined with the formation of mesenteric vein thrombosis. | 22020906 |
| Myocarditis, Myocarditis, CTCAE 5.0 | Altered Intercellular Communication | MRI has become the primary tool for assessment of myocardial inflammation in patients with suspected acute myocarditis. | 22021499 |
| Inflammation, Chronic heart failure, Metabolic Syndrome X, Congestive heart failure | Altered Intercellular Communication | Gluco-metabolic syndrome, oxidative stress and inflammation are common in chronic heart failure (CHF). | 22021702 |
| allergic inflammation | Altered Intercellular Communication | Exhaled nitric oxide is associated with allergic inflammation in children. | 22022176 |
| Airway structure, Asthma | Altered Intercellular Communication | Exhaled nitric oxide (eNO) has been proposed as a noninvasive marker of airway inflammation in asthma. | 22022176 |
| Asthma, allergic inflammation, IL13 gene | Altered Intercellular Communication | The purpose of this study was to assess the possible relationship between eNO and allergic inflammation or sensitization in childhood asthma and allergic rhinitis. | 22022176 |
| Allergic sensitization, allergic inflammation | Altered Intercellular Communication | This study reveals that eNO level is associated with allergic inflammation and the degree of allergic sensitization. | 22022176 |
| Inflammation | Altered Intercellular Communication | Inflammation is thought to play a role in the pathogenesis of major adverse cardiovascular events (MACE). | 22022185 |
| Inflammation | Altered Intercellular Communication | It has been suggested that the measurement of markers of inflammation may aid in predicting the risk of such events. | 22022185 |
| Inflammation, Bursitis, Traumatic injury, Pain Distress Question | Altered Intercellular Communication | Trochanteric bursitis is a common disorder that is characterized by inflammation of the bursa, superficial to the greater trochanter of the femur, leading to pain in the lateral hip, and often occurs because of acute trauma or repetitive friction involving the iliotibial band, the greater trochanter, and the bursa. | 22022680 |
| vascular inflammations, Atherosclerosis | Altered Intercellular Communication | In the elderly, GDF-15 reflects endothelial activation and vascular inflammation and thus, multiple pathways involved in the development and progression of atherosclerosis. | 22023041 |
| ARCN1 gene, Inflammation, Left ventricular diastolic dysfunction | Altered Intercellular Communication | In a cross-sectional design we aimed to evaluate the frequency of left ventricular diastolic dysfunction (LVdd) and its correlation with lung function, pulmonary arterial pressure and systemic inflammation in a selected population of COPD at an early stage of their disease. | 22023769 |
| Tendinitis, Inflammation, Musculoskeletal Diseases | Altered Intercellular Communication | The differential diagnoses include many musculoskeletal disorders like tendonitis and inflammation of ossicles. | 22024638 |
| Inflammation, Pelvic Pain, prostatitis, Pain Distress Question | Altered Intercellular Communication | Importantly, our study showed that OxS is also present in the case of NIH IIIb category prostatitis when the patients have just chronic pelvic pain but no inflammation in prostate-specific materials, as well as in the patients with just lower urinary tract symptoms without pain or overt inflammation. | 22025397 |
| Liver carcinoma, Neoplasm Metastasis | Altered Intercellular Communication | The role of polymeric immunoglobulin receptor in inflammation-induced tumor metastasis of human hepatocellular carcinoma. | 22025622 |
| Inflammation, Eales disease | Altered Intercellular Communication | Impact of interleukin-6 promoter polymorphism and serum interleukin-6 level on the acute inflammation and neovascularization stages of patients with Eales' disease. | 22025890 |
| Inflammation, Mediastinitis | Altered Intercellular Communication | This report describes three rare cases of mediastinitis caused by inflammation of the sternoclavicular joint. | 22026087 |
| Inflammation, Primary malignant neoplasm, Fibrosis Assessment, Heart failure, Kidney Diseases, Obesity | Altered Intercellular Communication | Galectin-3 is involved in fibrosis and inflammation and plays a role in heart failure, renal disease, obesity and cancer. | 22026577 |
| Inflammation, Liver Dysfunction | Altered Intercellular Communication | In patients undergoing hepatectomy, preoperative immunonutrition reduced inflammation and protected against liver dysfunction. | 22027191 |
| Steatohepatitis, Inflammation | Altered Intercellular Communication | Steatohepatitis was observed in seven patients (NAS >= 4) and (1)H MRS was able to predict it with 100% sensitivity and 89% specificity at threshold 10.9%, without knowing lobular inflammation or hepatocyte ballooning. | 22027576 |
| Inflammation, Fatty Liver Disease | Altered Intercellular Communication | Serum levels of IL-1RA, and liver mRNA expression of IL1RN are associated with NASH and the degree of lobular inflammation in liver (p<0.05). | 22027586 |
| Inflammation, Obesity | Altered Intercellular Communication | The decrease in serum IL-1RA level and expression of IL1RN after obesity surgery correlated with the improvement of lobular inflammation (p<0.05). | 22027586 |
| Non-alcoholic Fatty Liver Disease, Fatty Liver Disease | Altered Intercellular Communication | We developed a novel NAFLD Liver Inflammation Score, including serum Il-1RA concentration, which performed better to diagnose NASH than did previously published scores. | 22027586 |
| Nutritional Deficiency, Inflammation, Anemia | Altered Intercellular Communication | Many elderly patients have anemia due to nutritional deficiency, chronic inflammation, or comorbid diseases; however, in a significant fraction of the patients with anemia, the cause remains obscure. | 22028153 |
| Inflammatory Bowel Diseases, Inflammation, Colorectal Carcinoma | Altered Intercellular Communication | Patients with inflammatory bowel disease (IBD) have an increased risk of developing colorectal cancer due to chronic inflammation. | 22028324 |
| Inflammatory Bowel Diseases, Inflammation, SLC25A20 gene, Ulcerative Colitis-Associated Colorectal Adenocarcinoma | Altered Intercellular Communication | In IBD, chronic inflammation relies upon a TGFb signaling blockade, but its precise mechanistic relationship to colitis-associated colorectal cancer (CAC) remains unclear. | 22028324 |
| Inflammation, Liver carcinoma, Fibrosis Assessment, Hepatitis B, Hepatitis C, FAM126A gene, Liver Cirrhosis | Altered Intercellular Communication | Chronic inflammation caused by hepatitis B virus infection, hepatitis C virus infection, and/or heavy alcohol use can lead to fibrosis, cirrhosis, and eventually hepatocellular carcinoma (HCC). | 22028407 |
| Inflammation, Osteitis | Altered Intercellular Communication | Osteitis is associated with worse baseline measures of disease severity and inflammation. | 22028948 |
| Inflammation, Atherosclerosis | Altered Intercellular Communication | Lipoprotein-associated phospholipase A2 (LpPLA2) is a lipoprotein-bound enzyme involved in inflammation and atherosclerosis. | 22029180 |
| Inflammation, Carcinoma | Altered Intercellular Communication | Carcinomas are considered to be associated with increased cellular proliferation under antigenic stimulation and inflammation. | 22029199 |
| Inflammation, Squamous cell carcinoma of the head and neck | Altered Intercellular Communication | Therefore, the markers of increased cellular turnover such as adenosine deaminase and uric acid were estimated quantitatively along with markers of inflammation such as C-reactive protein in squamous cell carcinoma of head and neck region. | 22029199 |
| Granulomatous inflammation | Altered Intercellular Communication | A frozen section was taken from 16 patients but not the patient who received a CT-guided peritoneal biopsy, and all revealed granulomatous inflammation. | 22030041 |
| Inflammation, Diabetes Mellitus, Non-Insulin-Dependent, Aortic Stiffness | Altered Intercellular Communication | Aortic stiffness, inflammation, denutrition and type 2 diabetes in the elderly. | 22030242 |
| Inflammation, Cerebral Small Vessel Diseases | Altered Intercellular Communication | To clarify the role of inflammation in the pathogenesis of cerebral small vessel disease (SVD), we investigated whether the gene encoding transforming growth factor-beta 1(TGF-beta 1) is a risk factor for cerebral SVD as a whole, and for two different SVD subtypes. | 22030425 |
| Inflammation, Hypertensive (finding), Overweight, Obesity | Altered Intercellular Communication | The results suggested that additional cardiovascular risk could be demonstrated by the high prevalence of being overweight and central obesity presented by the population and the presence of subclinical inflammation amongst hypertensive ones. | 22030995 |
| Inflammation, Postpoliomyelitis Syndrome | Altered Intercellular Communication | An increase in cytokine in the cerebrospinal fluid suggests that inflammation is pathophysiologically important in post-polio syndrome. | 22031351 |
| Arthralgia, Pain Distress Question, Inflammation, Neuralgia | Altered Intercellular Communication | The pain was classified according to the International Association for the Study of Pain criteria as neuropathic when it occurred in an area with decreased sensibility, or nociceptive when signs of inflammation and/or painful joints movements were present. | 22031351 |
| NCI CTEP SDC Myelodysplastic Syndrome Sub-Category Terminology, Inflammation, Fever, CTCAE, Vasculitis, CTCAE | Altered Intercellular Communication | We describe the case of an elderly male patient whose presentation with prolonged unexplained fever coupled with cutaneous, pulmonary and other systemic features of inflammation was finally diagnosed as having a primary myelodysplastic syndrome with associated vasculitis after a delay of 4 years. | 22031795 |
| Inflammation, Atherosclerosis | Altered Intercellular Communication | Inflammation plays an important role in the pathophysiology of atherosclerosis. | 22032051 |
| Degenerative polyarthritis, Inflammation | Altered Intercellular Communication | Systemic inflammation and antibodies to citrullinated peptides in hand osteoarthritis. | 22032420 |
| Degenerative polyarthritis, Inflammation, 4-hydroxy-2-oxovalerate aldolase activity | Altered Intercellular Communication | To investigate systemic inflammation and autoimmune response to citrullinated peptides in patients with erosive and non erosive 'lone' hand osteoarthritis (HOA) with no hip/knee involvement and their relationship with radiographic structural damage. | 22032420 |
| Autoimmune Diseases, Inflammation | Altered Intercellular Communication | Our study underlines the lack of systemic inflammation and autoimmunity in 'lone' HOA and confirms the association between BMI and CRP levels. | 22032420 |
| Liver carcinoma, Infection, Virus Diseases, Hepatitis B, Hepatitis C, FAM126A gene, Hepatitis, Chronic, Primary Malignant Liver Neoplasm | Altered Intercellular Communication | Hepatocellular carcinoma (HCC) is the most common primary liver cancer, usually arising after years of chronic liver inflammation that could result from viral infections such as hepatitis B virus (HBV) and hepatitic C virus (HCV) infections. | 22032643 |
| Inflammation, Chronic Kidney Diseases | Altered Intercellular Communication | Chronic kidney disease (CKD) is a condition associated with inflammation and high levels of uremic toxins and reactive oxygen species. | 22032827 |
| Paresis, Fatigue | Altered Intercellular Communication | Inflammation-related muscle weakness and fatigue in geriatric patients. | 22032874 |
| Inflammation, Muscular Atrophy | Altered Intercellular Communication | Inflammation in older persons is associated with muscle wasting, leading to frailty and functional decline. | 22032874 |
| Chronic heart failure, Chronic inflammation, physiopathological | Altered Intercellular Communication | Chronic heart failure (HF) is characterised by a neurohormonal dysfunction associated with chronic inflammation. | 22032915 |
| Airway structure, Lung diseases | Altered Intercellular Communication | These findings indicate that IL-32 facilitates host defense against MAC organisms but may also contribute to the airway inflammation associated with MAC pulmonary disease. | 22033195 |
| Inflammation, Virus Diseases, Sensorineural Hearing Loss (disorder) | Altered Intercellular Communication | In addition, the occurrence of SNHL depends on the intensity and duration of the viral infection and inflammation. | 22033878 |
| Kidney Failure, Chronic, Inflammation, Cessation of life, Chronic Kidney Diseases | Altered Intercellular Communication | Associations between inflammation and ESRD and death in chronic kidney disease are well established. | 22034503 |
| Inflammation, Dysplasia, Ulcerative Colitis, Neoplasms | Altered Intercellular Communication | Whereas AID expression in UC-associated neoplasia was not correlated with the grade of dysplasia, expression in non-neoplastic mucosa of UC was correlated with the histological grade of inflammation. | 22034886 |
| Inflammation, Carcinogenesis, Ulcerative Colitis | Altered Intercellular Communication | AID is associated with inflammation in UC, whereas it may not specifically contribute to carcinogenesis in UC. | 22034886 |
| Chronic lymphocytic inflammation, Neoplasms | Altered Intercellular Communication | The inverse correlation of tumour buds with peritumoural lymphocytic inflammation suggests an interaction with specific immune responses. | 22034888 |
| Inflammation, Data types - Address | Altered Intercellular Communication | This is the first report that shows GMF, a mediator of central nervous system inflammation, is expressed in the brain regions affected in AD and that GMF is mainly localized in reactive astrocytes surrounding APs/NFTs. | 22035352 |
| Inflammation, Pustulosis of Palms and Soles, Acne, Synovitis, Osteitis, Musculoskeletal Diseases, Synovitis, Acne, Pustulosis, Hyperostosis, and Osteitis Syndrome, Skin Abnormalities, Hyperostosis | Altered Intercellular Communication | SAPHO syndrome (synovitis, acne, pustulosis, hyperostosis, and osteitis) is a rare chronic inflammatory musculoskeletal disorder of unknown etiology observed in children and young adults, which involves both osteo-articular inflammation and skin abnormalities. | 22035400 |
| Inflammation, Non-necrotizing granulomatous inflammation | Altered Intercellular Communication | Histopathology of the liver revealed diffuse granulomatous inflammation with confluent non-caseating granulomas compressing the centrolobular veins. | 22035428 |
| Airway structure | Altered Intercellular Communication | The flaw in the study is the higher doses of ICS in the control arms, but the implicit message remains: the essential need for enough ICS to control airway inflammation. | 22035511 |
| Inflammation, Squamous cell carcinoma of the head and neck | Altered Intercellular Communication | Loss of TGF-b signaling and PTEN promotes head and neck squamous cell carcinoma through cellular senescence evasion and cancer-related inflammation. | 22037217 |
| Idiopathic Pulmonary Fibrosis | Altered Intercellular Communication | To do so, we analyzed lung tissue from 21 cases of idiopathic pulmonary fibrosis and 21 (non-fibrotic, non-cancerous) controls for immune cell and inflammation-related markers. | 22037258 |
| Inflammation, Idiopathic Pulmonary Fibrosis | Altered Intercellular Communication | In summary, our study shows participation of innate and adaptive mononuclear cells in active-disease regions of idiopathic pulmonary fibrosis lung, where the regenerating epithelial cells appear to propagate inflammation. | 22037258 |
| Inflammation | Altered Intercellular Communication | Lipid diffusion into the joint cavity, which largely depends on the degree of inflammation, may contribute to modulating local inflammatory processes. | 22037510 |
| Inflammation, physiopathological | Altered Intercellular Communication | A senescent phenotype in endothelial cells is associated with increased apoptosis, reduced endothelial nitric oxide synthase (eNOS) and inflammation, which are implicated in arterial dysfunction and disease in humans. | 22037549 |
| Inflammation, Hematoma | Altered Intercellular Communication | Chemokines as markers of local inflammation and angiogenesis in patients with chronic subdural hematoma: a prospective study. | 22037980 |
| Inflammation | Altered Intercellular Communication | It is likely that these signaling modulators play an important role in promoting local inflammation. | 22037980 |
| vascular inflammations | Altered Intercellular Communication | Vascular inflammation and blood pressure response to acute exercise. | 22038148 |
| vascular inflammations | Altered Intercellular Communication | The purpose was to examine the association between systemic markers of vascular inflammation and exercise blood pressure (BP) responses. | 22038148 |
| Inflammation, Primary malignant neoplasm, Toxic liver disease, Cardiovascular Diseases | Altered Intercellular Communication | Even if the hypothesis of a possible hepatic toxicity of OTA in humans is yet to be verified, the positive association between plasma OTA and CRP may indicate a possible role of OTA in inflammation status and consequently in the genesis of cardiovascular diseases and cancer. | 22038465 |
| Inflammation, Spinal Cord Injuries | Altered Intercellular Communication | Fas/FasL-mediated apoptosis and inflammation are key features of acute human spinal cord injury: implications for translational, clinical application. | 22038545 |
| Inflammation, Stanford Cancer Institute | Altered Intercellular Communication | We found dramatically reduced inflammation and cytokines and chemokine expression in B6.MRL-Fas-lpr mice compared to Wt mice after SCI. | 22038545 |
| Inflammation, Dental Plaque, atherosclerotic | Altered Intercellular Communication | Distribution of inflammation within carotid atherosclerotic plaques with high-risk morphological features: a comparison between positron emission tomography activity, plaque morphology, and histopathology. | 22038986 |
| Inflammation, Thrombosis | Altered Intercellular Communication | Although plaque inflammation is also associated with atherothrombosis, the relationship between inflammation and number of HRM is not well understood. | 22038986 |
| atherosclerotic | Altered Intercellular Communication | Thirty-four patients underwent (18)flurodeoxyglucose positron emission tomography (FDG-PET) imaging, and carotid atherosclerotic inflammation was assessed (target-to- =0.0003) and increased with the number of HRM observed (P<0.001 for trend). | 22038986 |
| Inflammation, atherosclerotic | Altered Intercellular Communication | Similarly, inflammation within atherosclerotic specimens (% CD68 staining) was higher in plaques with (versus without) HRM (median [interquartile range]: 10 [0, 19.85] versus 0 [0, 1.55], P=0.01) and increased with the number of HRM observed (P<0.001 for trend). | 22038986 |
| Inflammation | Altered Intercellular Communication | Inflammation, as assessed by both FDG uptake and histology, is increased in plaques containing HRM and increases with increasing number of HRM. | 22038986 |
| Inflammation | Altered Intercellular Communication | These data support the concept that inflammation accumulates relative to the burden of morphological abnormalities. | 22038986 |
| Refractory anemias, Inflammation, Erosion lesion | Altered Intercellular Communication | This cytokine, as a downstream effector of TNFa and IL-1b, may contribute to inflammation and bone erosions in RA. | 22039170 |
| Inflammation | Altered Intercellular Communication | sADAM33 may be a biomarker of lung tissue inflammation and remodelling in sarcoid. | 22040125 |
| Gingivitis, Secondary caries, Abnormal color | Altered Intercellular Communication | Baseline and postcementation data were recorded for marginal integrity, marginal discoloration, secondary caries, retention, and gingival inflammation. | 22040467 |
| Gingivitis, Hemorrhage, Bone Diseases, Contusions, Petechiae | Altered Intercellular Communication | The condition presents itself by the formation of perifollicular petechiae and bruising, gingival inflammation and bleeding, and, in children, bone disease. | 22041118 |
| Inflammation, Sore to touch, Swelling, Inflammatory dermatosis | Altered Intercellular Communication | At midfoot level, clinical examination demonstrated signs suggestive for joint inflammation (tenderness and/or swelling) in at least one joint in 43/200 feet (21.5%) of 23 patients; US showed inflammatory abnormalities in 87/200 feet (43.5%) of 63 patients and structural lesions in 100/200 feet (50%) of 70 patients. | 22041178 |
| Nephritis | Altered Intercellular Communication | A number of chemokines and chemokine receptors are produced by intrinsic renal cells as well as by infiltrating cells during renal inflammation. | 22041342 |
| Nephritis | Altered Intercellular Communication | The CCR2 chemokine receptor mediates leukocyte chemoattraction in the initiation and amplification phase of renal inflammation. | 22041342 |
| Coughing, Inflammation, Chronic cough, MS4A2 wt Allele | Altered Intercellular Communication | FENO could be used as a inflammation marker of chronic cough because of its good correlation with sputum eosinophils, AHR, atopy, and cough symptoms. | 22041775 |
| Tears body substance, Inflammation, Keratoconjunctivitis Sicca, Inflammatory disorder | Altered Intercellular Communication | The use of punctal plugs in the treatment of keratoconjunctivitis sicca (KCS) in inflammatory eye disease remains controversial because of the potentially increased retention time of tears enriched with inflammatory cytokines that may aggravate eye inflammation. | 22041848 |
| Inflammatory abnormality of the eye | Altered Intercellular Communication | Punctal occlusion achieved a significant improvement in subjective symptoms and objective findings in ocular GvHD without increasing ocular inflammation. | 22041848 |
| Inflammation, Caseous necrosis, Granuloma | Altered Intercellular Communication | Various histologic features of nonreactive exudative inflammation were seen, along with granulomas containing Langhans giant cells with or without caseous necrosis in hypervascular organs, such as the lung, liver, and bone marrow. | 22041877 |
| Inflammation, Fibrosis Assessment, Necrosis | Altered Intercellular Communication | It produces tumor-like masses of the mesentery composed of varying degrees of fibrosis, chronic inflammation, and fat necrosis. | 22042424 |
| Autoimmune Diseases, Inflammation, Lupus Erythematosus, Lupus Erythematosus, Systemic | Altered Intercellular Communication | This study was designed to investigate the functional heterogeneity of human Th17 and how their plasticity shapes the nature of immune cell responses to inflammation and autoimmune diseases, such as systemic lupus erythematosus (SLE). | 22042490 |
| Pneumothorax, Pneumonitis | Altered Intercellular Communication | Effect of ageing and pulmonary inflammation on the incidence and number of cross-bridging structures in pneumothorax patients. | 22042982 |
| Inflammation, Obesity | Altered Intercellular Communication | The expression of specific microRNA species in obesity, which could also target and post-transcriptionally modulate cytokine mRNA, provides new insight into possible mechanisms of how risk factors might modify periodontal inflammation and may represent novel therapeutic targets. | 22043006 |
| Albumins | Altered Intercellular Communication | Malnutrition inflammation syndrome may contribute to a change of peritoneum, leading to high peritoneal membrane transport, peritoneal albumin loss, and increased glucose uptake into systemic circulation and decreased ultrafiltration (UF) volume. | 22043574 |
| Malnutrition | Altered Intercellular Communication | Subjective global assessment score (SGA), malnutrition inflammation score (MIS), and laboratory values were utilized to identify nutritional and inflammatory status. | 22043574 |
| Inflammation, Poliovirus Vaccine, Inactivated, Chronic disease | Altered Intercellular Communication | Lifetime occurrence of intimate partner violence (IPV) in women has been associated with increased prevalence of aging-related chronic diseases, including those with a pathophysiology involving inflammation. | 22044065 |
| Inflammation | Altered Intercellular Communication | IPV histories remitted for an average of 10 years were associated with biologic mediators of inflammation. | 22044065 |
| Inflammation, Dermatitis, Allergic Contact, Hypersensitivity | Altered Intercellular Communication | Allergic contact dermatitis (ACD) is a skin inflammation caused by an allergic reaction after contact with small external substances capable of being absorbed by the skin. | 22044472 |
| Inflammation, Thrombophilia | Altered Intercellular Communication | Storage lesions may promote inflammation and thrombophilia when transfused. | 22044745 |
| Pancreatitis, AURKAIP1 gene, Autoimmune Pancreatitis, Swelling, Waldenstrom Macroglobulinemia | Altered Intercellular Communication | Autoimmune pancreatitis (AIP), characterized by irregular narrowing of the main pancreatic duct, swelling of the pancreas, and histological evidence of lymphoplasmacytic inflammation by high serum immunoglobulin G4, is distinct from ordinary pancreatitis. | 22045429 |
| Inflammation, "Alzheimers Disease", Data types - Address | Altered Intercellular Communication | Inflammation plays a significant role in Alzheimer's disease (AD) pathogenesis. | 22045483 |
| Inflammation | Altered Intercellular Communication | We hypothesized that older adults with periodontal inflammation (PI) or many missing teeth would show impaired cognition compared to subjects without PI or with few missing teeth, and among subjects with PI, those with many missing teeth would show impaired cognition compared to those with few missing teeth. | 22045483 |
| Inflammation, Hypotension, CTCAE | Altered Intercellular Communication | However, there is some controversy concerning whether antioxidants might attenuate oxidative damage and inflammation in humans after hypotension in the setting of critical illness. | 22045831 |
| Paclitaxel Injection Concentrate for Nanodispersion, Sepsis, Fever, Chronic idiopathic neutropenia, Hematological Disease, Inflammatory disease of mucous membrane | Altered Intercellular Communication | Idiopathic chronic neutropenia (ICN) describes a heterogeneous group of hematologic diseases characterized by low circulating neutrophil levels often associated with recurrent fevers, chronic mucosal inflammation, and severe systemic infections. | 22047626 |
| Inflammation | Altered Intercellular Communication | The cooling and compression appeared to decrease inflammation, as indicated by a temperature-sensitive decrease in the PGE2 concentration. | 22048090 |
| Pain Distress Question, Inflammation | Altered Intercellular Communication | Since PGE2 is a marker of pain and inflammation, the postoperative local cooling and compression appeared to have a positive anti-inflammatory effect. | 22048090 |
| Inflammation, Pleurisy, Edema, Granuloma, Foreign-Body, Pleural Effusion, CTCAE | Altered Intercellular Communication | A lung biopsy was taken and revealed histologically: chronic non-specific inflammation in the pleuropulmonary border, intrapleural edema with eightfold pleural thickening in comparison to normal, angiogenesis in both the nutritive and functional intrapleural blood vessels, no abnormalities of lymphatic vessels with normal topographical distribution as detected by immunohistochemistry for antibody D2-40, granulomatous chronic foreign body reaction as a consequence of pleural effusion therapy by talcum pleurodesis.The histopathological findings of chronic non-specific pleuritis with angiogenesis and increased permeability of blood vessels led to massive intrapleural edema with pleural effusion. | 22048329 |
| Pregnancy Complications, Neoplastic, Communicable Diseases, Inflammation | Altered Intercellular Communication | Considering the features of this disease, they are probably secondary to chronic r infectious or immunological inflammation or paraneoplastic complications with angiogenesis (in about 19%). | 22048329 |
| Schizophrenia | Altered Intercellular Communication | Recent evidence suggests that schizophrenia may result from alterations of integration of signaling mediated by multiple neurotransmitter systems. | 22048463 |
| Inflammation, Carcinogenesis, Primary malignant neoplasm | Altered Intercellular Communication | Chronic oxidative stress and inflammation have been indicated as major mediators during carcinogenesis and cancer progression. | 22048816 |
| Inflammation, Diabetes Mellitus | Altered Intercellular Communication | To explore the putative association of new-onset diabetes and the soluble urokinase plasminogen activator receptor (suPAR), which is a new and stable plasma marker of immune function and low-grade inflammation. | 22050462 |
| Inflammation, polyps, Colorectal Carcinoma | Altered Intercellular Communication | Important endoscopic diagnoses were defined as colorectal cancer (CRC), polyps, diverticuli and inflammation. | 22050603 |
| Finger joint structure, Inflammation | Altered Intercellular Communication | Sum scores evaluated by grayscale US showed that synovial inflammation in finger joints was detected significantly more frequently in the palmar aspect than on the dorsal side (p = 0.001). | 22052070 |
| Inflammation, Hypertension, CTCAE, Haiti | Altered Intercellular Communication | However, the influence of cardiovascular risk factors and inflammation on the urinary levels of this marker in hypertension (HT) has never evaluated. | 22052073 |
| Inflammation, Traumatic injury, Pain Distress Question | Altered Intercellular Communication | The diagnosis group displaying the highest injury prevalence was inflammation and pain in the gradual onset category (1-year prevalence, 20.9%; 95% CI, 16.2%-26.2%; and point prevalence, 23.2%; 95% CI, 18.4%-28.7%). | 22053325 |
| Inflammation, Fibrosis Assessment | Altered Intercellular Communication | Routine laboratory markers Alb, BPC and WBC were significantly correlated with hepatic histological inflammation grade and fibrosis stage. | 22053373 |
| Fitz-Hugh-Curtis syndrome, Chlamydia trachomatis, Inflammation, Pelvic Inflammatory Disease | Altered Intercellular Communication | Fitz-Hugh-Curtis syndrome is an inflammation of the liver capsule as a complication of pelvic inflammatory disease, whose etiologic agent is the most common C. trachomatis. | 22054272 |
| Inflammation, Diabetes Mellitus, Non-Insulin-Dependent, Atherosclerosis | Altered Intercellular Communication | Type 2 diabetes mellitus and atherosclerosis are complex diseases sharing common antecedents like inflammation. | 22055258 |
| Inflammation, Atherosclerosis | Altered Intercellular Communication | CXCL16 is a chemokine involved in atherosclerosis by promoting inflammation, lipid accumulation and matrix degradation. | 22055341 |
| Fibrosis Assessment, Acute and chronic inflammation, Edema | Altered Intercellular Communication | Pancreatic duct size and index, fibrosis grade, fat content, edema, and signs of chronic and acute inflammation were measured in frozen sections of the resection margin and were then compared. | 22056514 |
| Granulomatous inflammation | Altered Intercellular Communication | Histopathological examination showed granulomatous inflammation in four patients. | 22056858 |
| Crohn Disease | Altered Intercellular Communication | The Lewis score (LS) and the Capsule Endoscopy Crohn's Disease Activity Index (CECDAI) have been developed to standardize the reporting of small-bowel inflammation. | 22057284 |
| Gastrointestinal inflammation | Altered Intercellular Communication | Fecal calprotectin (FC) represents a highly reliable biomarker of intestinal inflammation. | 22057284 |
| Inflammation, Cachexia | Altered Intercellular Communication | Inflammation in older persons is associated with frailty, cachexia, and disability. | 22057579 |
| Presenile dementia, Inflammation | Altered Intercellular Communication | Having eleven or more missing teeth seemed to be associated with a lower risk of dementia in people with lower education possibly owing to the suppression of source of chronic inflammation. | 22059867 |
| Inflammation | Altered Intercellular Communication | Interleukin (IL)-1b plays an important role in inflammation and has been associated with fibrotic remodelling. | 22059992 |
| vascular inflammations, Periodontitis, Atherosclerosis | Altered Intercellular Communication | It is suggested that periodontitis enhances the process of vascular inflammation leading to atherosclerosis. | 22060049 |
| Inflammation, physiopathological, Diabetes Mellitus, Non-Insulin-Dependent, Vascular Diseases | Altered Intercellular Communication | Adipose tissue dysfunction is associated with inflammation, type 2 diabetes mellitus and vascular diseases. | 22064157 |
| Refractory anemias, Rheumatoid Arthritis | Altered Intercellular Communication | Tacrolimus (TAC) suppresses immune-inflammation by an intermediary inhibition of calcineurin activation in the treatment of rheumatoid arthritis (RA). | 22065071 |
| Inflammation, Ureteral obstruction, Hydronephrosis | Altered Intercellular Communication | (18)F-fluoro-2-deoxy-D: -glucose positron emission tomography (FDG-PET)/computed tomography (CT) clearly depicted an inflammation of the left peri-iliac arterial soft tissue, which was thought to be the cause of the ureteral obstruction and hydronephrosis. | 22065104 |
| Hydronephrosis, Arteritis | Altered Intercellular Communication | Our case shows that peri-iliac arterial inflammation occurs in GPA and causes hydronephrosis. | 22065104 |
| Inflammation, Traumatic injury, Corneal keloid | Altered Intercellular Communication | This report describes a very rare case of bilateral corneal keloid in the absence of trauma or inflammation that was diagnosed by histological and immunohistochemical examination and electron microscopy. | 22067103 |
| Exanthema, Stomatitis, Ulceration, CTCAE, Inflammatory disease of mucous membrane, Fatigue | Altered Intercellular Communication | Related adverse events were generally mild or moderate and consisted primarily of stomatitis, mucosal inflammation, mouth ulceration, rash, and fatigue. | 22067397 |
| Inflammation Mediators, Uveitis | Altered Intercellular Communication | To interrogate inflammation-mediated angiogenesis, we investigated experimental autoimmune uveoretinitis, an animal model for human uveitis. | 22067906 |
| Inflammation | Altered Intercellular Communication | Increased alveolar nitric oxide and systemic inflammation markers in silica-exposed workers. | 22068172 |
| Inflammation, Cardiovascular Diseases | Altered Intercellular Communication | High levels of fetuin-A has been linked to cardiovascular disease, possibly via modulating low-grade systemic inflammation. | 22068809 |
| Chemosis of conjunctiva, Inflammation, Ophthalmoplegia, Edema | Altered Intercellular Communication | Patients may present with preseptal inflammation, lid edema, chemosis, or ophthalmoplegia. | 22070879 |
| Inflammation, Primary malignant neoplasm, Infectious agent | Altered Intercellular Communication | Chronic inflammation associated with some infectious agents can lead to cancer. | 22070917 |
| Inflammation, Primary malignant neoplasm | Altered Intercellular Communication | Vagal nerve activity may predict prognosis in cancer due to its roles in modulating inflammation, sympathetic activity and oxidative stress. | 22070982 |
| Inflammation, Chronic Obstructive Airway Disease | Altered Intercellular Communication | Low-grade adipose tissue inflammation in patients with mild-to-moderate chronic obstructive pulmonary disease. | 22071714 |
| ARCN1 gene, Inflammation, Chronic Obstructive Airway Disease | Altered Intercellular Communication | Low-grade systemic inflammation is common in chronic obstructive pulmonary disease (COPD), but its source remains unclear. | 22071714 |
| ARCN1 gene, Inflammation, Hypoxia | Altered Intercellular Communication | Adipose tissue is a potent producer of inflammatory mediators and may contribute to systemic inflammation in COPD, possibly via hypoxia. | 22071714 |
| ARCN1 gene, Inflammation | Altered Intercellular Communication | We studied the influence of COPD and exercise-induced oxygen desaturation on adipose tissue inflammation (ATI) and its contribution to systemic inflammation. | 22071714 |
| ARCN1 gene, Inflammation | Altered Intercellular Communication | In COPD patients, mild-to-moderate COPD, per se, does not enhance ATI or its contribution to systemic inflammation compared with in well-matched healthy control subjects. | 22071714 |
| Refractory anemias, Inflammation | Altered Intercellular Communication | Construct validity and reliability of ultrasound disease activity score in assessing joint inflammation in RA: comparison with DAS-28. | 22072084 |
| Refractory anemias, Arthritis | Altered Intercellular Communication | To investigate the construct validity and reliability of US DAS compared with 28-joint DAS (DAS-28) in assessing joint inflammation and in prediction of structural damage in patients with RA. | 22072084 |
| Inflammation, Malignant Neoplasms | Altered Intercellular Communication | A diagnosis of malignancy in the ampulla was only made after several ERCP attempts due to residual inflammation at the periampullary area. | 22072249 |
| Inflammation, Cardiovascular Diseases | Altered Intercellular Communication | Low-grade inflammation and increased immunity related to cardiovascular diseases have been described in children and adults, however, studies in Mexican adolescents are being done at present. | 22072361 |
| Hyperammonemia, Inflammation, Impaired cognition | Altered Intercellular Communication | To assess the contribution of hyperammonemia and inflammation to induction of mild cognitive impairment (or MHE). | 22072427 |
| Nonalcoholic Steatohepatitis, Inflammation, Psoriasis, Hyperammonemia, Non-alcoholic Fatty Liver Disease, Liver Cirrhosis, Fatty Liver Disease | Altered Intercellular Communication | The study included patients with 1) liver cirrhosis, showing hyperammonemia and inflammation; 2) non-alcoholic fatty liver disease (NAFLD) showing inflammation but not hyperammonemia; 3) non-alcoholic steatohepatitis (NASH) showing inflammation and very mild hyperammonemia; 4) psoriasis, showing inflammation but not hyperammonemia; 5) keloids, showing both inflammation and hyperammonemia and 6) controls without inflammation or hyperammonemia. | 22072427 |
| Inflammation, Impaired cognition, Liver diseases, Hyperammonemia, Liver Cirrhosis | Altered Intercellular Communication | The data reported show that in patients with liver diseases, cognitive impairment may appear before progression to cirrhosis if hyperammonemia and inflammation are high enough. | 22072427 |
| Inflammation, Impaired cognition, Hyperammonemia, Liver Cirrhosis, Fatty Liver Disease | Altered Intercellular Communication | Five out of 11 patients with NASH, without liver cirrhosis, showed cognitive impairment associated with hyperammonemia and inflammation. | 22072427 |
| Hyperammonemia, Inflammation, Hepatobiliary Disorder, Impaired cognition | Altered Intercellular Communication | Patients with keloids showed cognitive impairment associated with hyperammonemia and inflammation, in the absence of liver disease. | 22072427 |
| Hyperammonemia, Inflammation, Hepatobiliary Disorder | Altered Intercellular Communication | Hyperammonemia or inflammation alone did not induce CI but the combination of certain levels of hyperammonemia and inflammation is enough to induce CI, even without liver disease. | 22072427 |
| Inflammation, Cyclophosphamide/Vincristine/Dacarbazine Regimen, Cardiovascular Diseases | Altered Intercellular Communication | Circulating C-reactive protein (CRP), reflective of systemic chronic low-grade inflammation, is a marker associated with cardiovascular disease (CVD). | 22072642 |
| Inflammation | Altered Intercellular Communication | One of the mechanisms through which physical activity might promote cardiovascular health is by preventing changes in inflammation biomarkers, such as CRP. | 22072642 |
| Neurogenic Inflammation, Dental Plaque | Altered Intercellular Communication | The increased plaque and neuronal inflammation were accompanied by the generation of N(e)-carboxymethyl lysine in advanced glycation end products, a rapid marker of oxidative damage, induced by Sod1 gene-dependent reduction. | 22072713 |
| Gingivitis, Demographics Domain | Altered Intercellular Communication | DM subjects with a low educational background, having higher HbA1c% and males are more likely to experience gingival inflammation. | 22073462 |
| Pain Distress Question, Inflammation | Altered Intercellular Communication | Genetic factors play a role in the etiology of persistent pain conditions, putatively by modulating underlying processes such as nociceptive sensitivity, psychological well-being, inflammation, and autonomic response. | 22074755 |
| Synovitis, Inflammation, Rheumatoid Arthritis, Edema of bone marrow | Altered Intercellular Communication | Correlation between computer-aided dynamic gadolinium-enhanced MRI assessment of inflammation and semi-quantitative synovitis and bone marrow oedema scores of the wrist in patients with rheumatoid arthritis--a cohort study. | 22075065 |
| Refractory anemias, Inflammation, Synovitis, Edema of bone marrow | Altered Intercellular Communication | To test the correlation between assessment of inflammation using dynamic contrast-enhanced MRI (DCE-MRI) analysed by a novel computer-aided approach and semi-quantitative scores of synovitis and bone marrow oedema (BME) using the OMERACT-RA MRI Scoring (RAMRIS) system, in the wrist of patients with RA. | 22075065 |
| Inflammation | Altered Intercellular Communication | This technique may be useful for quick semi-automated assessment of joint inflammation, but needs further validation. | 22075065 |
| Inflammation, Myositis | Altered Intercellular Communication | The inflammatory myopathies (IMs) are a group of disorders characterised by weakness and inflammation of the skeletal muscles. | 22075187 |
| Chronic inflammation, Rheumatoid Arthritis, Crohn Disease, Inflammatory Breast Carcinoma, Disease | Altered Intercellular Communication | Transsignaling of interleukin (IL)-6 is a central pathway in the pathogenesis of disorders associated with chronic inflammation, such as Crohn disease, rheumatoid arthritis, and inflammatory colon cancer. | 22075248 |
| 22q11.2 | Altered Intercellular Communication | [Growth hormone deficiency associated with 22q11.2 deletion: a case report]. | 22075807 |
| Hypoplasia of the pituitary gland, DiGeorge Syndrome, hormone deficiency, teratologic | Altered Intercellular Communication | We found growth hormone deficiency and pituitary hypoplasia associated with some of the anomalies shown above, thus we suspected and confirmed the 22q11.2 deletion syndrome. | 22075807 |
| ARCN1 gene, Chronic Obstructive Airway Disease | Altered Intercellular Communication | Neutrophilic airway inflammation is one of the key features of chronic obstructive pulmonary disease (COPD). | 22076427 |
| Inflammation | Altered Intercellular Communication | The chemokine receptors 1 (CXCR1) and 2 (CXCR2) are expressed in the bronchial mucosa during chronic inflammation and might be of importance for transepithelial migration of neutrophils. | 22076427 |
| Inflammation, Obesity | Altered Intercellular Communication | The results indicate that the two kinds of protein can modestly improve serum lipids and markers associated with obesity and inflammation. | 22077928 |
| Inflammation, Arthritis | Altered Intercellular Communication | Adiponectin is an adipokine that regulates energy metabolism and insulin sensitivity, but recent studies have pointed also to a role in inflammation and arthritis. | 22077999 |
| Cartilage destruction, Inflammation, Degenerative polyarthritis | Altered Intercellular Communication | The purpose of the present study was to investigate the association and effects of adiponectin on inflammation and cartilage destruction in osteoarthritis (OA). | 22077999 |
| Inflammation, Atrial Fibrillation by ECG Finding | Altered Intercellular Communication | Lipoprotein(a) and inflammation in patients with atrial fibrillation after electrical cardioversion. | 22078666 |
| Pain Distress Question, Inflammation | Altered Intercellular Communication | Substance P (SP) and calcitonin gene-related peptide (CGRP) are released by the nociceptive sensory nerve and are involved in blood flow, pain and inflammation in the nasal mucosa. | 22079125 |
| Inflammation, Thrombosis, Peripheral Arterial Diseases, Cerebrovascular accident, Cerebrovascular Disorders, Hypertension, CTCAE | Altered Intercellular Communication | MPV is now considered a link between inflammation and thrombosis in multiple cardiovascular and cerebrovascular disorders including hypertension, peripheral artery disease, and stroke. | 22079338 |
| Airway structure, Asthma | Altered Intercellular Communication | The role of low-level lactate production in airway inflammation in asthma. | 22080752 |
| Inflammation, Asthma | Altered Intercellular Communication | The objective was to study aerobic glycolysis in human asthma and the role of this metabolic pathway in airway hyperreactivity and inflammation in a mouse model of asthma. | 22080752 |
| Airway structure, Asthma, Hyperreactivity | Altered Intercellular Communication | DCA also inhibited airway inflammation and hyperreactivity in a mouse model of asthma. | 22080752 |
| Bacteremia, Communicable Diseases, Inflammation | Altered Intercellular Communication | Significant improvements from H-Surg to H-IR catheters include the reduction in exit-site inflammation and infection (27.8% to 5.4%) and in bacteremic episodes (72.2% to 27.0%). | 22080756 |
| Inflammation, Granulation finding | Altered Intercellular Communication | Pathologic review showed non-necrotizing granulomatous inflammation with granulation tissue. | 22082596 |
| Inflammation, Atherosclerosis, Hyperglycemia, Obesity, Hypertension, CTCAE | Altered Intercellular Communication | High-sensitivity C-reactive protein (hs-CRP) is a marker for low-grade inflammation, as well as atherosclerosis, obesity, hyperglycemia and hypertension. | 22082888 |
| Phlebitis, Retractile Mesenteritis | Altered Intercellular Communication | Sclerosing mesenteritis is a rare, benign disorder characterized by non-specific and chronic inflammation of the mesenteric adipose tissue. | 22082901 |
| Hypercalcemia, CTCAE | Altered Intercellular Communication | [Hypercalcemia associated with parathyroid hormone-related protein(PTHrP)in a patient with diffuse large- type B-cell lymphoma(DLBCL)]. | 22083203 |
| Inflammation, Squamous cell carcinoma | Altered Intercellular Communication | The importance of stromal inflammation in squamous cell carcinoma of the tongue. | 22084865 |
| Burn Specimen Source Codes, Pneumonitis | Altered Intercellular Communication | Pulmonary levels of suPAR are elevated in burn patients with inhalation trauma, and they correlate with pulmonary inflammation and coagulation. | 22085408 |
| Inflammation, Organ Dysfunction Scores, Critical Illness | Altered Intercellular Communication | We analyzed serum HA levels in 164 critically ill patients at a medical ICU and 61 healthy controls, with respect to organ dysfunction, systemic inflammation and mortality. | 22085533 |
| Inflammation, Atherosclerosis | Altered Intercellular Communication | Ageing is an important determinant of atherosclerosis development rate, mainly by the creation of a chronic low-grade inflammation. | 22085595 |
| Celiac Disease, Inflammation | Altered Intercellular Communication | Duodenum biopsy demonstrated short villi, chronic inflammation and an increase in the number of intraepithelial lymphocytes, all these was consistent with celiac disease Marsh 3. | 22086322 |
| Cardiovascular Diseases, Presenile dementia, Cerebrovascular accident, Vasculitis, Hypertension, CTCAE | Altered Intercellular Communication | Hypertension, a key risk factor for stroke, cardiovascular disease and dementia, is associated with chronic vascular inflammation, and although poorly understood, putative mechanisms include pro-inflammatory responses induced by mechanical stretching, with cytokine release and associated up-regulated expression of adhesion molecules. | 22086659 |
| Respiratory Distress Syndrome, Adult, Inflammation, Respiratory Distress Syndrome, Newborn, Peritonitis | Altered Intercellular Communication | Acute respiratory distress syndrome (ARDS) occasionally occurs after gastrointestinal surgery involving severe inflammation such as diffuse peritonitis. | 22086692 |
| hearing impairment, Inflammation | Altered Intercellular Communication | Age-related hearing loss is a common disabling condition but its causes are not well understood and the role of inflammation as an influencing factor has received little consideration in the literature. | 22086966 |
| Granulomatous inflammation | Altered Intercellular Communication | The diagnosis may be problematic since the known causes of granulomatous inflammation must be excluded. | 22087521 |
| Inflammation, COL4A2 wt Allele | Altered Intercellular Communication | The role of inflammation in the pathophysiology of ICH is increasingly recognized. | 22087759 |
| Inflammation | Altered Intercellular Communication | These associations might be attributed to the chronic inflammation induced by excess adiposity. | 22088365 |
| Inflammation | Altered Intercellular Communication | A call for observations of such cases was sent to members of the French "Club rhumatismes et inflammation". | 22088934 |
| ARCN1 gene, Inflammation | Altered Intercellular Communication | Effect of fruit and vegetable intake on oxidative stress and inflammation in COPD: a randomised controlled trial. | 22088966 |
| ARCN1 gene, Inflammation | Altered Intercellular Communication | Increasing FV intake may attenuate the oxidative stress and inflammation associated with COPD. | 22088966 |
| ARCN1 gene, Inflammation | Altered Intercellular Communication | An exploratory randomised controlled trial to examine the effect of increased consumption of FV on oxidative stress and inflammation in moderate-to-severe COPD was conducted. | 22088966 |
| Airway structure, Inflammation | Altered Intercellular Communication | There were no significant changes in biomarkers of airway inflammation (interleukin-8 and myeloperoxidase) and systemic inflammation (C-reactive protein) or airway and systemic oxidative stress (8-isoprostane). | 22088966 |
| Inflammation, Dryness (characteristic), Irritation | Altered Intercellular Communication | Elevation in MUC1 and MUC16 mRNA and/or protein levels in postmenopausal women with non-Sjogren dry eye with a history of dry eye may be a compensatory response to irritation and inflammation associated with the disease. | 22089171 |
| Inflammation, Traumatic injury | Altered Intercellular Communication | Indices of systemic inflammation in this human inflammation model were compared with those of 12 trauma patients with a mean injury severity score of 19. | 22089204 |
| Inflammation, Endotoxemia, Traumatic injury | Altered Intercellular Communication | Neutrophil activation was present 3 h after onset of inflammation, both during experimental endotoxemia as well as in trauma patients. | 22089204 |
| Granulomatous inflammation | Altered Intercellular Communication | Granulomatous inflammation is a distinctive pattern of chronic inflammatory reaction characterized by accumulation of epithelioid histiocytes and multinucleate giant cells. | 22089785 |
| Inflammation, Aortic Valve Stenosis | Altered Intercellular Communication | Assessment of valvular calcification and inflammation by positron emission tomography in patients with aortic stenosis. | 22090163 |
| Inflammation, Aortic Valve Stenosis | Altered Intercellular Communication | The pathophysiology of aortic stenosis is incompletely understood, and the relative contributions of valvular calcification and inflammation to disease progression are unknown. | 22090163 |
| Inflammation, Aortic Valve Stenosis | Altered Intercellular Communication | Positron emission tomography is a novel, feasible, and repeatable approach to the evaluation of valvular calcification and inflammation in patients with aortic stenosis. | 22090163 |
| Inflammation, Atrial Fibrillation by ECG Finding, osteoclast activating factor, Postpericardiotomy Syndrome, Pericarditis, CTCAE | Altered Intercellular Communication | Inflammation and pericarditis may be contributing factors for postoperative atrial fibrillation (POAF), and both are potentially affected by antiinflammatory drugs and colchicine, which has been shown to be safe and efficacious for the prevention of pericarditis and the postpericardiotomy syndrome (PPS). | 22090167 |
| Inflammation, Graves Disease | Altered Intercellular Communication | Metallothioneins (MT) are small proteins induced by tissue stress that can contribute to restoring homeostasis of tissue inflammation and have been found to be increased in a transcriptomic analysis of Graves' disease (GD) glands. | 22090273 |
| Inflammation, Sinusitis, Meningitis | Altered Intercellular Communication | Ongoing inflammation in maxillary sinuses detected in brain MRI suggested that meningitis could be related to previous sinus infection. | 22090306 |
| Delirium, Inflammation, Malnutrition, Atherosclerosis | Altered Intercellular Communication | In addition, frailty and delirium may have shared pathophysiology, such as inflammation, atherosclerosis, and chronic nutritional deficiencies, which will require further investigation. | 22091571 |
| Inflammation, Osteopenia, GDC AJCC Clinical Stage Terminology | Altered Intercellular Communication | Compared with patients with no significant stenosis, poor periodontal health including missing teeth, periodontal inflammation, and bone loss is associated with angiographically verified coronary artery narrowing in patients with stable CAD or ACS. | 22092472 |
| Inflammation | Altered Intercellular Communication | Bone loss was associated with complex multiple coronary lesions, beyond systemic inflammation. | 22092604 |
| Inflammation | Altered Intercellular Communication | An increase in cytokines at 48 h after the challenge was demonstrated and might, with further studies, give us a better understanding of the nature of inflammation in AKC. | 22092652 |
| Inflammation | Altered Intercellular Communication | Inflammation and oxidative stress are lower in physically fit and active adults. | 22092747 |
| Inflammation | Altered Intercellular Communication | These data indicate that an inverse relationship exists among chronic inflammation, oxidative stress, and pFIT and ExFreq at the community level even after adjustment for important confounders. | 22092747 |
| Inflammation, Psoriasis | Altered Intercellular Communication | Psoriasis is characterized by lower stratum corneum (SC) hydration and dermal inflammation. | 22092918 |
| Pain Distress Question, Inflammation | Altered Intercellular Communication | Statistically significant factors influencing this potential choice were number of episodes of pain (P=0.006, OR=1.23, 95% CI: 1.060-1.430) and number of attacks of inflammation (P=0.048, OR=1.27, 95% CI: 1.002-1.598). | 22093049 |
| Inflammation, Fibrosis Assessment, Calcinosis | Altered Intercellular Communication | Histopathology of pericardial specimens was reviewed and evaluated semiquantitatively on a 4-point scale for the extent of calcification, fibrosis, inflammation, and neovascularization. | 22093269 |
| Inflammation, Granulation finding | Altered Intercellular Communication | The DHE+ group had greater fibroblastic proliferation and neovascularization, as well as more prominent chronic inflammation and granulation tissue. | 22093269 |
| Inflammation | Altered Intercellular Communication | Fibroblastic proliferation and chronic inflammation correlated with DHE presence quantitated by DHE score (Spearman r = 0.578, p < 0.002, and r = 0.590, p < 0.002, respectively), but not with pericardial thickness. | 22093269 |
| Coronary Artery Disease | Altered Intercellular Communication | Prevalence and risk factors of carotid vessel wall inflammation in coronary artery disease patients: FDG-PET and CT imaging study. | 22093271 |
| Inflammation | Altered Intercellular Communication | Carotid inflammation was quantified in 82 CAD patients (age 62 +- 10 years) as the maximum target-to-background ratio ((wholevessel)TBR(max)). | 22093271 |
| Inflammation, Hypertension, CTCAE, Obesity | Altered Intercellular Communication | Carotid inflammation as revealed by FDG-PET is highly prevalent in the CAD population and is associated with obesity, age over 65 years, history of hypertension, smoking, and male gender. | 22093271 |
| helium, Hepatic Encephalopathy, Gastrointestinal inflammation, Bacterial peritonitis | Altered Intercellular Communication | Bacterial translocation, causing intestinal inflammation, is one of the key mechanisms in the pathogenesis of hepatic encephalopathy (HE) and spontaneous bacterial peritonitis (SBP) The presence of fecal calprotectin quantitatively relates to intestinal neutrophil migration and is therefore considered as a marker of intestinal inflammation. | 22093455 |
| Cirrhotic | Altered Intercellular Communication | FCCs were higher in cirrhotic subjects with additional extra-intestinal inflammation (P<0.01; sensitivity=0.65, specificity=0.8). | 22093455 |
| Inflammation, Cirrhotic | Altered Intercellular Communication | The Pearsons correlation coefficients were 0.190 and 0.164 revealing no influence (P=0.142 and P=0.207) of laboratory parameters of systemic inflammation on FCCs in cirrhotic subgroup. | 22093455 |
| Inflammation | Altered Intercellular Communication | In case of subcutaneous and intramuscular injection of metallic mercury we recommend marginal or wide excision of all contaminated tissue to prevent migration of mercury and chronic inflammation. | 22093686 |
| Primary sclerosing cholangitis, Gastrointestinal inflammation, Inflammatory Bowel Diseases | Altered Intercellular Communication | The relationship between site of intestinal inflammation and primary sclerosing cholangitis (PSC) development in inflammatory bowel disease (IBD) has not been studied extensively, but may be important in understanding the pathogenesis of PSC. | 22094024 |
| Inflammation | Altered Intercellular Communication | A higher release of polyethylene and metal particles is triggered, which leads to a slow but continuous process of inflammation. | 22094154 |
| Cough variant asthma, Inflammation, Coughing, Cerebrovascular accident, Asthma, Respiratory Hypersensitivity | Altered Intercellular Communication | Cough variant asthma (CVA) is a phenotype of asthma presenting solely with coughing, characterized by airway hyperresponsiveness, eosinophilic inflammation and a cough response to bronchodilators. | 22094623 |
| Inflammation, Cerebrovascular accident | Altered Intercellular Communication | The antitussive effect of montelukast in CVA may be attributed to the attenuation of eosinophilic inflammation rather than its bronchodilatory properties. | 22094623 |
| deficiency aspects | Altered Intercellular Communication | Hormonal deficiency may partially account for this finding. | 22094737 |
| Airway structure | Altered Intercellular Communication | However, the mode of the underlying chronic airway inflammation is different. | 22094827 |
| Deposition, Interstitial inflammation | Altered Intercellular Communication | We also correlated the presence/absence of interstitial inflammation and IgG subclasses in the TBM and vascular deposits. | 22095887 |
| Interstitial inflammation | Altered Intercellular Communication | Interstitial inflammation did not correlate with the presence of IgG staining or distribution of IgG subclasses in the TBM. | 22095887 |
| Interstitial inflammation | Altered Intercellular Communication | Interstitial inflammation was more common in biopsies of African-American patients than Caucasian patients. | 22095887 |
| Tubulitis Assessment, Interstitial inflammation, Glomerulitis (disorder) | Altered Intercellular Communication | Two pathologists, blinded to clinical data, reviewed biopsies from 30 patients according to a standardized protocol that included assessment of T cell, B cell, and plasma cell infiltration, as well as scoring for tubulitis, interstitial inflammation, and glomerulitis. | 22095945 |
| Inflammation, renal anemia | Altered Intercellular Communication | This study sought to determine whether high-flux dialysis would help improve markers of renal anemia, inflammation, and oxidative stress compared with low-flux dialysis. | 22096040 |
| Inflammation | Altered Intercellular Communication | Markers of inflammation, oxidative stress, or nutritional status also did not differ between groups. | 22096040 |
| Inflammation | Altered Intercellular Communication | Chronic inflammation, as reflected by increased level of acute phase protein such as C-reactive Protein (CRP) is highly prevalent in hemodialysis patients. | 22097096 |
| Inflammation | Altered Intercellular Communication | Our study provides further support for a role of inflammation in the pathophysiology of suicidality. | 22098148 |
| Inflammation, Fibrosis Assessment, Lesion of liver, Fatty Liver Disease | Altered Intercellular Communication | In morbid obese patients, NASH, particularly lobular inflammation and advanced fibrosis, associates with mild decreases in eGFR, suggesting a common inflammatory link between liver and renal lesion. | 22098270 |
| Inflammation, Destruction of tissue | Altered Intercellular Communication | In addition, the frequent poor tooth conservation and gingival inflammation tend to amplify tissue destruction and symptoms and may impair and confuse the correct diagnosis, thus delaying the onset of specific treatment. | 22098533 |
| High Density Lipoproteins, Inflammation, Nerve Degeneration | Altered Intercellular Communication | CSF showed signs of neurodegeneration without inflammation, and autopsy verified HDLS in Case 1. | 22098561 |
| Inflammation, Chronic liver disease | Altered Intercellular Communication | Inflammation is a major factor for the progression of chronic liver diseases. | 22098627 |
| Fibrosis Assessment, Hepatic inflammation | Altered Intercellular Communication | Interactions between urokinase plasminogen activator (uPA) and its receptor (uPAR) have been functionally linked to hepatic inflammation and fibrosis in mice. | 22098627 |
| Inflammation, Fibrosis Assessment | Altered Intercellular Communication | Circulating suPAR closely correlated with liver function, fibrosis markers, but also with systemic inflammation and renal function. | 22098627 |
| Inflammation, Metabolic Syndrome X | Altered Intercellular Communication | In additional models adjustments were performed for the single components constituting the metabolic syndrome and for inflammation. | 22098712 |
| Inflammation, Metabolic Syndrome X | Altered Intercellular Communication | These relations were not influenced by the individual components of metabolic syndrome or by inflammation. | 22098712 |
| Prostate carcinoma, prostatitis | Altered Intercellular Communication | More evidence indicate that prostate inflammation can lead to prostate cancer development. | 22098728 |
| Urinary tract infection, prostatitis | Altered Intercellular Communication | Ciprofloxacin is an antibacterial agent used mainly in urinary tract infections and prostate inflammation. | 22098728 |
| Primary malignant neoplasm, prostatitis | Altered Intercellular Communication | Firstly, ciprofloxacin can stop the acute and chronic prostate inflammation which can lead to cancer development. | 22098728 |
| Gingivitis | Altered Intercellular Communication | A 18-year-old girl with gingival inflammation particularly in the maxillary insicor area was referred to the authors' department. | 22099313 |
| Inflammation, Inflammatory disorder | Altered Intercellular Communication | In addition, macrophage migration inhibitory factor (MIF) is a key upstream regulator of inflammation, and it is a significant regulator of inflammatory diseases. | 22099602 |
| Inflammation, Atrial Fibrillation | Altered Intercellular Communication | Our findings provide additional evidence for the relation between systemic inflammation and AF. | 22100030 |
| Inflammation, Atherosclerosis | Altered Intercellular Communication | The interplay between oxidative stress and inflammation is crucial in the pathogenesis of atherosclerosis. | 22100252 |
| Inflammation | Altered Intercellular Communication | Inflammation may play an essential role in the decline of physical performance. | 22100319 |
| Inflammation, Congenital Heart Defects | Altered Intercellular Communication | Patients presenting with cardiac abnormalities and evidence of systemic inflammation should be screened for Wegener's by history, radiographic and laboratory assessment. | 22100479 |
| Inflammation, Data types - Address | Altered Intercellular Communication | Specifically, three hypotheses may explain the role of GSTO1-1 in the pathophysiology of AD: the antioxidant activity of GSTO1-1 may protect brain tissue against oxidative stress; GSTO1-1 activity regulate interleukin-1b activation and its genetic variation may act to modulate inflammation in AD; GSTO1-1 is involved in the arsenic biotransformation pathway and gene polymorphisms may be implicated in the modulation of arsenic neurotoxicity. | 22100662 |
| Autoimmune Diseases, Inflammation, "Sjogrens Syndrome | Altered Intercellular Communication | Decreased salivary sulphotransferase activity correlated with inflammation and autoimmunity parameters in Sjogren's syndrome patients. | 22101162 |
| Inflammation, Carcinogenesis | Altered Intercellular Communication | The mast cells participate in inflammation and possibly in carcinogenesis. | 22102069 |
| Cardiovascular system | Altered Intercellular Communication | It is not known whether state-level variation in cardiovascular inflammation exists or could be explained by traditional clinical risk factors and behavioral lifestyle factors. | 22102899 |
| Nonalcoholic Steatohepatitis, Inflammation, Fibrosis Assessment | Altered Intercellular Communication | Although there was less inflammation (p = 0.038) and fibrosis (p = 0.029), non-alcoholic steatohepatitis and fibrosis were present in 61% and 55% of the Lean-NAFLD group, respectively. | 22103042 |
| Inflammation, Non-alcoholic Fatty Liver Disease, Metabolic Syndrome X | Altered Intercellular Communication | Fish oil improves lipid metabolism and ameliorates inflammation in patients with metabolic syndrome: impact of nonalcoholic fatty liver disease. | 22103753 |
| Fibrosis Assessment, Non-alcoholic Fatty Liver Disease, Hepatitis, Liver Cirrhosis | Altered Intercellular Communication | NAFLD can lead to liver inflammation, fibrosis and cirrhosis. | 22103753 |
| Inflammation, Heart failure, Pathology | Altered Intercellular Communication | We analyzed in parallel the proteomic profile of subjects with cardiac heart failure to discriminate these two pathologies, which show similar pattern of systemic inflammation process. | 22104004 |
| Airway structure, Asthma | Altered Intercellular Communication | Exhaled nitric oxide has been promoted as a non-invasive measure of airway inflammation, with clinical utility for the diagnosis and management of asthma. | 22104032 |
| Airway structure | Altered Intercellular Communication | Airway inflammation as measured by exhaled nitric oxide in young New Zealand children is related to their level of specific IgE to aeroallergens. | 22104032 |
| Inflammation | Altered Intercellular Communication | Our results demonstrate that IGFBP-1 mRNA and protein is detected at increased levels in human carotid plaques, possibly as a consequence of plaque inflammation. | 22104117 |
| Inflammation | Altered Intercellular Communication | Patients with HF-REF or HF-PEF presenting similar symptoms and functional limitations exhibit similar concentrations of biomarkers of ECM and inflammation. | 22104539 |
| Pyelonephritis, Xanthogranulomatous, Pyelonephritis, Tuberculosis, Secondary malignant neoplasm of kidney, Renal abscess, Renal Cell Carcinoma Pathway | Altered Intercellular Communication | Focal xanthogranulomatous pyelonephritis (XGP) is a chronic inflammatory condition that can mimic other disease conditions such as pyelonephritis, tuberculosis, renal abscess, renal cell carcinoma, and renal metastasis. | 22105452 |
| Eosinophilic disorder | Altered Intercellular Communication | Kimura disease is an uncommon chronic inflammatory condition of unknown etiology and is characterized by painless subcutaneous nodules, usually affecting the head and neck, eosinophilia, and markedly elevated immunoglobulin E levels. | 22106083 |
| Inflammation | Altered Intercellular Communication | ANCA specific to several antigens may worsen inflammation by reducing antimicrobial capacity of neutrophil proteases and cationic proteins. | 22107137 |
| Gastrointestinal inflammation | Altered Intercellular Communication | Calprotectin is a calcium- and zinc-binding protein and a marker in faeces of gastrointestinal inflammation. | 22108340 |
| Inflammation | Altered Intercellular Communication | HIV-infected children older than 4 years had a median FC concentration above the reference value, and gut inflammation in the children with elevated values is likely. | 22108340 |
| Peripheral ulcerative keratitis, Keratitis | Altered Intercellular Communication | Peripheral ulcerative keratitis is a destructive process involving perilimbal corneal inflammation and an overlying epithelial defect. | 22108363 |
| Thrombus, Inflammation, Edema | Altered Intercellular Communication | Antithromboembolic stockings can help eliminate edema of the legs in MS patients, and may also reduce the thrombotic risk: the lower d-Dimer values suggest an effect on the activation of inflammation and coagulation resulting from stasis-induced endothelial damage. | 22108480 |
| Inflammation, Abnormality of mitochondrial metabolism | Altered Intercellular Communication | Those proteins may be associated with oxidative stress, mitochondrial dysfunction, abnormal protein aggregation and inflammation. | 22108571 |
| Entity Risk - Corrosive, Inflammation, Esophageal reflux observation, Fibrosis Assessment, congenital stenosis, Stenosis, Esophageal Achalasia, Post-Traumatic Stress Disorder, Ulcer of esophagus | Altered Intercellular Communication | The strictures had a range of causes: postoperative anastomotic stricture, corrosive stricture, postradiation stricture, esophageal achalasia, esophageal reflux, congenital stricture, esophageal web, esophageal ulcer, medication fibrosis, chronic inflammation, and posttraumatic stricture (in descending order of frequency). | 22109306 |
| vascular inflammations | Altered Intercellular Communication | (18)F-Fluorodeoxyglucose (FDG) positron emission tomography (PET)/CT has the potential to track vascular inflammation and monitor therapeutic response. | 22109668 |
| Arteritis | Altered Intercellular Communication | The medium dose of atorvastatin over a 12-week period resulted in a significant reduction of arterial inflammation as well as various circulating biomarkers. | 22109668 |
| Inflammation | Altered Intercellular Communication | Chronic low-grade inflammation and adipokines dysregulation are linked to mechanisms underscoring the pathogenesis of obesity-related metabolic disorders. | 22110665 |
| Secondary malignant neoplasm of lung, Amenorrhea, Aggressive course, Bothered by Vomiting, Phenotypic abnormality, Anemia, Nausea | Altered Intercellular Communication | Our case report suggest that PGC is a highly aggressive tumor that is often associated with liver and lungs metastasis without evidence of pelvic organ abnormality and is associated with some hormonal effects, such as amenorrhea, anemia, nausea and vomiting mimicking pregnancy in young adult female | 22111476 |
| Inflammation, Northeast, HIV Infections | Altered Intercellular Communication | The role of vaccination against HSV-2 in near future and elimination of HSV-2 viral shedding along with genital tract inflammation in high HIV/HSV-2 areas may be an option for initiating successful intervention strategies to reduce the transmission and acquisition of HIV infection in Northeast India. | 22111810 |
| Osteomyelitis, Inflammation | Altered Intercellular Communication | Fluorodeoxyglucose positron-emission tomography-computed tomography (FDG-PET-CT) revealed severe inflammation of the CVC wall and a picture consistent with osteomyelitis and severe destruction of the body of the 11th thoracic vertebra. | 22111828 |
| Inflammation, Osteoporosis | Altered Intercellular Communication | However, no direct association could be revealed between lower bone density and markers of inflammation or inflammatory cytokines, except of IL-6 witch was significantly higher in AS patients with osteoporosis/osteopenia than those without. | 22112431 |
| Inflammation, Osteopenia | Altered Intercellular Communication | Inflammation might contribute to the accelerated bone loss in AS through stimulation of bone degradation. | 22112431 |
| atherosclerotic | Altered Intercellular Communication | Altered expression of inflammation-related genes in human carotid atherosclerotic plaques. | 22112851 |
| Inflammation, Atherosclerosis | Altered Intercellular Communication | Inflammation is a pivotal process in atherosclerosis development and progression, but the underlying molecular mechanisms remain largely obscure. | 22112851 |
| Tumor necrosis | Altered Intercellular Communication | The positive association of tumor necrosis factor-a and nuclear factor-kB might be involved in the potential anti-inflammation mechanism of fish oil. | 22113064 |
| Inflammation, Stomach Carcinoma, Infection caused by Helicobacter pylori, Herpes | Altered Intercellular Communication | The development of gastric cancer (GC) is closely related to chronic inflammation caused by Helicobacter pylori infection, and herpes virus entry mediator (HVEM) is a receptor expressed on the surface of leukocytes that mediates potent inflammatory responses in animal models. | 22113134 |
| Inflammation, Rheumatoid Factor, Anemia | Altered Intercellular Communication | Exams revealed mild anemia, elevation of the biological parameters of inflammation and aminotransferases, positive cryoglobulin and rheumatoid factor in serum, and a severe reduction in C4 complement fraction. | 22113605 |
| Product Withdrawals, Inflammation, Gastrointestinal symptom | Altered Intercellular Communication | Moderate gluten doses also triggered mucosal inflammation and more gastrointestinal symptoms leading to premature withdrawals in seven cases. | 22115041 |
| Inflammation, Corneal edema | Altered Intercellular Communication | Graft rejection was defined as findings of keratic precipitates with or without corneal edema, or anterior chamber cell and flare with or without corneal edema after the initial resolution of perioperative inflammation. | 22115709 |
| Lymphatic Invasion Assessment, Inflammation, Neoplasms | Altered Intercellular Communication | The corresponding pathology slides showed only 1 of the 12 patients had dermal lymphatic invasion, whereas the other 11 specimens showed peritumoral inflammation without evidence of tumor invasion. | 22116117 |
| Lymphatic Invasion Assessment, Inflammation | Altered Intercellular Communication | This study demonstrates that the linear areas of reticulation are most commonly caused by peritumoral inflammation and are not due to dermal lymphatic invasion. | 22116117 |
| Inflammation, Vitreous Hemorrhage, Retinal Detachment, Injury of lens, Endophthalmitis, CTCAE | Altered Intercellular Communication | No cases had marked inflammation, lens injuries, marked vitreous hemorrhage, retinal detachment, or endophthalmitis. | 22116499 |
| Inflammation, Malignant Neoplasms | Altered Intercellular Communication | There were 29 lesions of different final diagnosis, including 17 recurrence rectal cancers, 4 fibrous masses, 6 stoma inflammations, 1 sinus and 1 abscess. | 22116720 |
| Inflammation, Swelling, Hyperemia | Altered Intercellular Communication | At presentation, mild anterior segment inflammation was observed, together with sheathing mainly of the veins as well as hyperemia and swelling of the optic disc in the fundus. | 22117324 |
| Retinal Vasculitis, Papilledema, Intraocular Lymphoma | Altered Intercellular Communication | Intraocular lymphoma may present with atypical findings of optic disk inflammation and retinal vasculitis. | 22117324 |
| Inflammation, Diabetic Retinopathy | Altered Intercellular Communication | Fundus examination showed no signs of inflammation, but both a narrowing of the retinal arterioles and non-active diabetic retinopathy were observed. | 22117326 |
| Inflammation, hepcidin | Altered Intercellular Communication | In conclusion, serum hepcidin levels are associated with iron status and microinflammation (defined as hsCRP < 15 mg/l, without clinical manifestation of inflammation) in maintenance haemodialysis patients. | 22118000 |
| Intestinal metaplasia, Inflammation, Atrophic | Altered Intercellular Communication | Activity and inflammation were mostly moderate or severe, while intestinal metaplasia and atrophy were mostly absent at all three sites. | 22118692 |
| Intestinal metaplasia, Inflammation, Atrophic | Altered Intercellular Communication | Atrophy and intestinal metaplasia are rare but activity and chronic inflammation are severe at the antrum, angulus and corpus in NG. | 22118692 |
| Fibrosis Assessment, Hepatic inflammation, Hepatitis B | Altered Intercellular Communication | Significant hepatic inflammation was found in 59.3% of these patients, and significant hepatic fibrosis was found in 62.1%, the latter being associated with hepatitis B e antigen status, ALT levels and serum HBV-DNA, but not with their age group or viral genotype. | 22118698 |
| Inflammation, Adverse Event Associated with Constitutional Symptoms, Musculoskeletal Pain, Anemia, Thrombocytosis | Altered Intercellular Communication | Compared with GCA patients with elevated markers of inflammation, a greater proportion of these patients had polymyalgia rheumatica symptoms (P = 0.008), whereas constitutional symptoms, anemia and thrombocytosis, were observed less often (P < 0.05). | 22119103 |
| Inflammation, Cyclophosphamide/Vincristine/Dacarbazine Regimen, Cardiovascular Diseases | Altered Intercellular Communication | Vitamin A affects inflammation and immune function and is thus a factor of interest in relation to cardiovascular disease (CVD). | 22119336 |
| Parkinson Disease, Inflammation | Altered Intercellular Communication | Markers of inflammation in prevalent and incident Parkinson's disease in the Cardiovascular Health Study. | 22119505 |
| Parkinson Disease, Inflammation, palladium | Altered Intercellular Communication | Studies demonstrate existence of inflammation in prevalent Parkinson's disease (PD). | 22119505 |
| palladium, Inflammation | Altered Intercellular Communication | Although inflammation exists in PD, it may not represent an etiologic factor. | 22119505 |
| Inflammation | Altered Intercellular Communication | suPAR was significantly positively correlated with markers of systemic inflammation (i.e., high sensitive C-reactive protein (hsCRP) and white blood cells (WBC), but not to lipoprotein-associated phospholipase A2 (Lp-PLA(2)), a specific vascular inflammatory biomarker.87 subjects had a CVD event during follow-up (mean 14.1 years). | 22119508 |
| Inflammation, Intellectual Disability | Altered Intercellular Communication | Inflammation and oxidative stress as biomarkers of premature aging in persons with intellectual disability. | 22119683 |
| Inflammation, Intradermal Route of Drug Administration | Altered Intercellular Communication | Our hypothesis was that chronic inflammation in the bloodstream of persons with ID contributes to their "premature aging". | 22119683 |
| Inflammation, Intradermal Route of Drug Administration | Altered Intercellular Communication | Asymptomatic inflammation in the bloodstream of the older adults with ID might explain the "premature aging" of these individuals. | 22119683 |
| Primary CNS Vasculitis | Altered Intercellular Communication | Primary central nervous system vasculitis (PCNSV) is a rare and poorly described vascular inflammatory condition confined within the central nervous system (CNS). | 22120304 |
| Pancreatic Neoplasm, Inflammation | Altered Intercellular Communication | MHC class II expression in pancreatic tumors: a link to intratumoral inflammation. | 22120497 |
| Inflammation, Coronary Artery Disease | Altered Intercellular Communication | The pathogenesis of coronary artery disease (CAD) is closely associated with inflammation, in which human leukocyte antigens (HLA), especially HLA-DR molecules, play important roles. | 22122841 |
| Refractory anemias, Inflammation | Altered Intercellular Communication | Overall, our findings suggest that CD4(+)CD28(-) T cells migrate in response to a chemotactic gradient of fractalkine to sites of inflammation, where they contribute to the inflammatory processes in a subgroup of patients with MS and RA. | 22123179 |
| Inflammation, Osseous metaplasia, Neoplasms, Skin, Osteoma cutis | Altered Intercellular Communication | Primary osteoma cutis arises in otherwise unaffected skin, often in patients with systemic conditions, whereas secondary osteoma cutis is associated with cutaneous neoplasms and inflammation (metaplastic ossification). | 22123193 |
| allergic inflammation | Altered Intercellular Communication | Insufficient Treg and Th1 cells may be associated with the allergic inflammation that may be attributed to the Th2 immune response in patients suffering from AR who are sensitive to olive pollen. | 22123238 |
| ARCN1 gene, Inflammation | Altered Intercellular Communication | Chronic inflammation plays an important role in both diseases: lung cancer and COPD. | 22123552 |
| Inflammation, Carcinoma of lung | Altered Intercellular Communication | However, it seems that inflammation is more pronounced in patients with lung cancer, as the CRP levels were significantly higher in these patients than other groups. | 22123552 |
| Orbital Pseudotumor | Altered Intercellular Communication | The differences of tear inflammatory cytokines between patients with active and inactive TAO indicated that orbital inflammation may be involved in the ocular surface damage of TAO. | 22124787 |
| Inflammation, Colorectal Carcinoma, Sinonasal Adenocarcinoma | Altered Intercellular Communication | Intestinal-type sinonasal adenocarcinoma (ITAC) is an epithelial cancer of the sinonasal sinuses that shows histological similarity to colorectal cancer (CRC) and share chronic inflammation as a possible etiological factor. | 22125792 |
| Inflammation, Hemorrhage, Dental Plaque | Altered Intercellular Communication | Gingival inflammation index, plaque index, probing depth, periodontal attachment level (AL), and bleeding on probing were taken for each subject. | 22126098 |
| Inflammation | Altered Intercellular Communication | It occurs frequently in conditions characterized by immune activation and inflammation. | 22126431 |
| Inflammation, Fibrosis Assessment | Altered Intercellular Communication | Baseline NAS was associated with progressive disease in a univariate binary logistic regression analysis (p = 0.024), but no difference was seen in the multivariate analysis including the NAS, portal inflammation, and perisinusoidal fibrosis. | 22126450 |
| Communicable Diseases, Phlebitis of portal vein, Septic thrombophlebitis, Inflammation | Altered Intercellular Communication | Pylephlebitis is defined as septic thrombophlebitis of the portal venous system, usually secondary to infection or inflammation in the abdomen. | 22126528 |
| Intraventricular | Altered Intercellular Communication | Intraventricular inflammation may be one mechanism by which IVH exerts deleterious effects. | 22126859 |
| Inflammation, Refractory anemias, Rheumatoid Arthritis, Anemia, hepcidin | Altered Intercellular Communication | To explore the utility of the novel iron indices hepcidin, reticulocyte hemoglobin content (Ret-Hgb), and erythrocyte (red blood cell) hemoglobin content (RBC-Hgb) for detection of iron deficiency in rheumatoid arthritis (RA) patients with anemia and active inflammation and to compare these indices with conventional parameters of iron deficiency. | 22127690 |
| Inflammation, Anemia, idarubicin, Chronic disease | Altered Intercellular Communication | Forty patients were classified as having either iron deficiency anemia (IDA), anemia of chronic disease (ACD), their combination (IDA/ACD), or "other anemia" based on biochemical parameters for inflammation and iron deficiency. | 22127690 |
| Refractory anemias, Inflammation, hepcidin, Anemia | Altered Intercellular Communication | Serum hepcidin and, to a lesser extent, urine hepcidin, Ret-Hgb, and RBC-Hgb, are potential useful indicators for detecting iron deficiency in RA patients with anemia and active inflammation. | 22127690 |
| Inflammation, Rheumatoid Arthritis | Altered Intercellular Communication | Inflammation and autoantibody markers identify rheumatoid arthritis patients with enhanced clinical benefit following rituximab treatment. | 22127691 |
| Sample Size Calculation, vascular inflammations, Fibrosis Assessment, Connective Tissue Diseases | Altered Intercellular Communication | Systemic sclerosis (SSc) is a connective tissue disease characterized by vascular inflammation and fibrosis. | 22127711 |
| Barrett Esophagus, Inflammation, Acid reflux, Rough endoplasmic reticulum | Altered Intercellular Communication | Frequent gastroesophageal reflux (GER) causes chronic inflammation and damages esophageal mucosa, which can lead to Barrett's esophagus. | 22128757 |
| Inflammation, Diabetes Mellitus | Altered Intercellular Communication | Evidence suggests vitamin D deficiency, perturbed glucose homeostasis, and increased inflammation all play roles in the development of diabetes. | 22129188 |
| Tissue Congestion, Heart failure | Altered Intercellular Communication | We examined the hypothesis that renal congestion is responsible for the decline in renal function in patients with heart failure (HF) via tubulointerstitial inflammation. | 22129502 |
| Inflammation, Venous Engorgement | Altered Intercellular Communication | Venous congestion may contribute to HF-induced deterioration of renal function by augmenting oxidative stress-mediated inflammation in the tubulointerstitium. | 22129502 |
| Inflammation, Metabolic Syndrome X, Acute myocardial infarction, Thrombus, MS gene | Altered Intercellular Communication | Metabolic syndrome (MS) may lead to worsened left ventricular systolic function by causing recurrent thrombotic events and by aggravating systemic inflammation in the course of acute myocardial infarction. | 22129921 |
| Inflammation | Altered Intercellular Communication | A biopsy led to the diagnosis of non-specific inflammation. | 22130730 |
| Orbital Pseudotumor | Altered Intercellular Communication | This case shows that sudden periorbital hemorrhages can be a sign for idiopathic orbital inflammation. | 22130730 |
| Airway structure, Allergic asthma, Allergy - Charge Type Reason | Altered Intercellular Communication | Inhalant exposure reduction with TLA improves quality of life, airway inflammation and systemic allergy in patients with persistent atopic asthma. | 22131290 |
| Cytopenia, Dermatitis, Lupus Erythematosus, Systemic | Altered Intercellular Communication | These clinical associations with SNPs in the promoter and 3' UTR regions align with previously reported SLE-susceptibility SNPs in OPN and suggest potential roles for these variants in antibody-mediated cytopenias and skin inflammation in SLE. | 22131818 |
| Coma (genus), Inflammation, Phlegmon, Inflammatory Breast Carcinoma | Altered Intercellular Communication | Several hours of pressure on the right breast during a coma was the cause of inflammation which appeared to be phlegmon or inflammatory breast cancer. | 22132625 |
| Orbital Pseudotumor | Altered Intercellular Communication | Orbital inflammation: a rare association of common variable immunodeficiency. | 22132851 |
| Common Variable Immunodeficiency, Orbital Pseudotumor | Altered Intercellular Communication | We describe a unique case of a patient with CVID who developed orbital inflammation. | 22132851 |
| Abnormal ocular motility, Exophthalmos, Orbital Pseudotumor | Altered Intercellular Communication | The patient was successfully treated with a course of oral prednisolone which resulted in improvement of orbital inflammation, ocular movements and proptosis. | 22132851 |
| Common Variable Immunodeficiency, Non-necrotizing granulomatous inflammation | Altered Intercellular Communication | To our knowledge this is the first reported case of non-granulomatous orbital inflammation in association with CVID. | 22132851 |
| Inflammation, Exacerbation of asthma | Altered Intercellular Communication | Noninvasive testing of lung function and inflammation in pediatric patients with acute asthma exacerbations. | 22133263 |
| Inflammation, Exacerbation of asthma | Altered Intercellular Communication | There is limited information on performance rates for tests of lung function and inflammation in pediatric patients with acute asthma exacerbations. | 22133263 |
| Communicable Diseases, Inflammation | Altered Intercellular Communication | Higher CSF cytokine levels (IL-8, p = 0.003; TNF-a, p = 0.019) were associated with the infection, but systemic inflammation results were controversial. | 22133280 |
| Presenile dementia, Inflammation | Altered Intercellular Communication | It can be concluded that inflammation plays an important role in both types of dementia. | 22133543 |
| Refractory anemias, Inflammation | Altered Intercellular Communication | Multiple inflammatory pathways contribute to persistent chronic inflammation in RA. | 22133625 |
| Pneumonitis, Systemic Scleroderma | Altered Intercellular Communication | Latent pulmonary inflammation in patients with systemic sclerosis. | 22133713 |
| Pneumonitis | Altered Intercellular Communication | Induced sputum is a non-invasive method for studying pulmonary inflammation. | 22133713 |
| Pulmonary function tests, Pneumonitis, Systemic Scleroderma | Altered Intercellular Communication | To assess pulmonary inflammation by analysis of induced sputum specimens in patients with systemic sclerosis and lung involvement, and to determine whether there is a correlation with the pulmonary function alterations in these patients. | 22133713 |
| Pneumonitis, Systemic Scleroderma | Altered Intercellular Communication | Pulmonary inflammation was present in all patients with systemic sclerosis included in the study, regardless of the presence of documented signs of pulmonary involvement. | 22133713 |
| Presenile dementia, Inflammation | Altered Intercellular Communication | The findings indicate that chronic caregiving of those with dementia may result in increased inflammation and, thereby, possibly increased CVD risk. | 22133914 |
| Inflammation, Heart failure, Depression, CTCAE | Altered Intercellular Communication | Cognitive/affective and somatic/affective symptom dimensions of depression are associated with current and future inflammation in heart failure patients. | 22134045 |
| Inflammation, Heart failure, Bipolar Disorder | Altered Intercellular Communication | Little is known about whether cognitive/affective depressive symptoms or somatic/affective depressive symptoms are associated with inflammation in heart failure (HF), or that the relation is confounded with disease severity. | 22134045 |
| Inflammation, Depression, CTCAE | Altered Intercellular Communication | Further studies are warranted to replicate these findings and to examine the association between depression dimensions, inflammation and prognosis in HF. | 22134045 |
| Inflammation, Uveal Effusion Syndrome | Altered Intercellular Communication | Due to the the presence of a nanophthalmic eye without any evidence of inflammation or malignant growth, the diagnosis uveal effusion syndrome could be made. | 22134345 |
| Inflammation, Androgenetic Alopecia | Altered Intercellular Communication | The role of inflammation and immunity in the pathogenesis of androgenetic alopecia. | 22134564 |
| Inflammation, Androgenetic Alopecia | Altered Intercellular Communication | Biopsies from men with androgenetic alopecia showed a similar pattern of inflammation and immunoreactant deposition. | 22134564 |
| Inflammation, Obesity, Metaphyseal irregularity | Altered Intercellular Communication | Obesity is associated with chronic low-grade inflammation, which contributes to systemic metabolic irregularities and obesity-linked metabolic disorders. | 22134720 |
| Inflammation, physiopathological | Altered Intercellular Communication | Orosomucoid (ORM), an acute phase reactant protein, was shown to be produced in response to metabolic and inflammatory signals in the adipose tissue of obese mice, which protects them from severe inflammation and subsequent metabolic dysfunction. | 22134720 |
| Inflammation | Altered Intercellular Communication | The close links of ORM and measures of adiposity, insulin resistance, and adipose tissue inflammation in humans reinforce previous experimental data and warrant further studies to explore a possible role of ORM in the pathogenesis of obesity-associated metabolic derangements. | 22134720 |
| Inflammation, physiopathological | Altered Intercellular Communication | Orosomucoid (ORM), an acute phase reactant protein, was shown to be produced in response to metabolic and inflammatory signals in the adipose tissue of obese mice, which protects them from severe inflammation and subsequent metabolic dysfunction. | 22134720 |
| Inflammation, Cerebrovascular accident | Altered Intercellular Communication | Consumption of antioxidant-rich foods may reduce the risk of stroke by inhibition of oxidative stress and inflammation. | 22135074 |
| Airway structure, Cystic Fibrosis | Altered Intercellular Communication | Bile acids in sputum and increased airway inflammation in patients with cystic fibrosis. | 22135379 |
| Airway structure | Altered Intercellular Communication | Aspiration of BA was associated with increased airway inflammation. | 22135379 |
| ARCN1 gene, Inflammation, Hypercapnia | Altered Intercellular Communication | Sleep-related hypoxemia and hypercapnia are well recognized in COPD and the development of systemic inflammation during sleep. | 22135488 |
| Inflammation, Weight decreased | Altered Intercellular Communication | Reduced chemerin expression and serum concentration may contribute to improved insulin sensitivity and subclinical inflammation beyond significant weight loss. | 22136911 |
| Inflammation, Neoplasms, Necrosis | Altered Intercellular Communication | Tumors grown in Se- mice were loosely packed and showed increased necrosis and inflammation as compared to those in Se and Se+ mice. | 22137259 |
| vascular inflammations | Altered Intercellular Communication | Association between sRAGE, esRAGE levels and vascular inflammation: analysis with (18)F-fluorodeoxyglucose positron emission tomography. | 22137663 |
| vascular inflammations | Altered Intercellular Communication | (18)F-fluorodeoxyglucose positron emission tomography (FDG-PET) is a novel imaging technique for detecting vascular inflammation. | 22137663 |
| Inflammation, Vascular Diseases, Purpura, Agranulocytosis lab result, Vasculitis, CTCAE | Altered Intercellular Communication | Known side effects of cocaine-related levamisole ingestion have included agranulocytosis and a cutaneous acral purpura that is histopathologically characterized by a mixture of inflammation (vasculitis) and occlusion (vasculopathy). | 22138808 |
| Unknown (origin) (qualifier value), Fibrosis Assessment, Interstitial inflammation | Altered Intercellular Communication | It is usually associated with chronic interstitial inflammation and fibrosis but may occasionally be idiopathic. | 22139352 |
| Pain Distress Question, Inflammation | Altered Intercellular Communication | Only one patient with persistent back pain underwent surgery for stabilization of the spine after the improvement of inflammation. | 22139720 |
| Inflammation, Neoplasms, Crypt hyperplasia | Altered Intercellular Communication | Pathological conditions within the small bowel such as loss of villi, crypt hyperplasia, advanced neoplasia, or increased blood flow due to inflammation tissue could be successful visualized. | 22139876 |
| Inflammation | Altered Intercellular Communication | Lobular inflammation occurred in 20.8% of the livers and PT inflammation in 38.8%. | 22139908 |
| Inflammation, Heat-Shock Response | Altered Intercellular Communication | It is increasingly clear that some heat shock proteins (Hsps) play a role in inflammation. | 22140545 |
| Inflammation, HSPD1 wt Allele | Altered Intercellular Communication | Hsp60 induction by NFkB-p65 and its release by epithelial cells after oxidative stress can have a role in maintaining inflammation, e.g., by stimulating neutrophils activity. | 22140545 |
| ARCN1 gene, Inflammation, Cardiovascular Diseases, Chronic Obstructive Airway Disease, Inflammatory disorder | Altered Intercellular Communication | Chronic obstructive pulmonary disease (COPD) is considered to be a systemic inflammatory disease, and systemic inflammation has been noted as a factor contributing to cardiovascular disease, which is one of the comorbidities associated with COPD. | 22142478 |
| Inflammation, Rheumatoid Vasculitis, Aortitis | Altered Intercellular Communication | Aortitis, inflammation of the aortic tissue, is most commonly caused by vasculitic rheumatic conditions, and less frequently infectious organisms. | 22143340 |
| Pain Distress Question, Inflammation | Altered Intercellular Communication | Analgesics and left-over antibiotics were used to ease pain and reduce inflammation. | 22144453 |
| Inflammation, Pathology | Altered Intercellular Communication | A central role of A2A and A3 adenosine receptors (ARs) in mechanisms of inflammation has been reported in different pathologies. | 22146575 |
| Arthritis | Altered Intercellular Communication | A2A and A3AR density inversely correlated with DAS28 and DAS suggesting a direct role of the endogenous activation of these receptors in the control of RA joint inflammation. | 22146575 |
| Coronary Arteriosclerosis | Altered Intercellular Communication | Serum concentrations of IgG4 and sIL-2R were increased in patients with angiographically-proven CAD, suggesting that IgG4-related immuno-inflammation may also have a role in the development and/or progression of coronary artery atherosclerosis. | 22146599 |
| Inflammation, Ulcer | Altered Intercellular Communication | Nevertheless, after having stopped the inflammation, the ulcers can be treated by split thickness skin grafts and simultaneous immunosuppression. | 22146897 |
| Inflammation, leukemia | Altered Intercellular Communication | Gingival inflammation and platelet count in patients with leukemia: preliminary results. | 22147236 |
| vascular inflammations | Altered Intercellular Communication | Recent findings indicate that at least 2 separate lineages of CD4+ T cells, Th1 and Th17 cells, participate in vascular inflammation. | 22147555 |
| Symptoms, Inflammation, Thyroid Gland | Altered Intercellular Communication | The data included demographics, indication for surgery, compressive symptoms, complications, diagnosis, volume of thyroid gland, presence of inflammation, and follow-up. | 22147633 |
| Symptoms, Inflammation | Altered Intercellular Communication | There was not a significant relationship between compressive symptoms and the presence of inflammation (P=.869). | 22147633 |
| ARCN1 gene, Inflammation, Skeletal muscle weakness, Cachexia | Altered Intercellular Communication | COPD is a multicomponent disease and systemic inflammation represents one of the possible mechanisms responsible for its systemic manifestations, including skeletal muscle weakness and cachexia. | 22149400 |
| ARCN1 gene, Inflammation | Altered Intercellular Communication | We hypothesized that the multidimensional BODE index, that reflects the multicomponent nature of COPD, might be related to biomarkers of systemic inflammation. | 22149400 |
| ARCN1 gene, Inflammation | Altered Intercellular Communication | Systemic inflammation was evaluated with the measurement of leptin, adiponectin, CRP, IL-6, and TNF-a in serum samples of COPD patients. | 22149400 |
| ARCN1 gene, Inflammation, Muscular Atrophy | Altered Intercellular Communication | The additional association of FFMI with TNF-a may further support a role of systemic inflammation in muscle wasting in COPD. | 22149400 |
| Inflammation, Exanthema, Eccrine Glands, hyponatremic | Altered Intercellular Communication | In patients with PHA1, miliaria rubra-like cutaneous eruptions are suggested to occur due to obstruction of eccrine sweat glands through inflammation caused by excessive sodium excretion in sweat during hyponatremic crises. | 22150373 |
| Inflammation | Altered Intercellular Communication | The operation had been started laparoscopically and converted to an open procedure because of severe chronic or acute inflammation. | 22151444 |
| Inflammation | Altered Intercellular Communication | Extreme vasculobiliary injuries tend to occur when fundus-down cholecystectomy is performed in the presence of severe inflammation. | 22151444 |
| Acute inflammation | Altered Intercellular Communication | Contractive inflammation thickens and shortens the cystic plate, making separation of the gallbladder from the liver hazardous. | 22151444 |
| Inflammation, Injury wounds | Altered Intercellular Communication | Both chronic wounds and impaired acute wounds are characterized by excessive inflammation, enhanced proteolysis, and reduced matrix deposition. | 22151742 |
| Intraocular inflammation | Altered Intercellular Communication | The diagnosis of PE was defined as severe intraocular inflammation requiring prompt vitreous sampling for culture. | 22151787 |
| Inflammation, "Alzheimers Disease", Data types - Address | Altered Intercellular Communication | Inflammation is a prominent feature in Alzheimer's disease (AD). | 22152162 |
| Inflammation | Altered Intercellular Communication | It has been proposed that aging has an effect on the function of inflammation in the brain, thereby contributing to the development of age-related diseases like AD. | 22152162 |
| Inflammation, Data types - Address | Altered Intercellular Communication | However, the age-dependent relationship between inflammation and clinical phenotype of AD has never been investigated. | 22152162 |
| Inflammation, Injury of liver | Altered Intercellular Communication | COX-2 expressed in liver may be a marker to reflect the degree of inflammation and injury of liver tissue. | 22152242 |
| Vasculitis, AAVS1 gene, Inflammation | Altered Intercellular Communication | In anti-neutrophil cytoplasmic autoantibody (ANCA)-associated vasculitides (AAV), persistent inflammation within the vessel wall suggests perturbed neutrophil trafficking leading to accumulation of activated neutrophils in the microvascular compartment. | 22152684 |
| Inflammation | Altered Intercellular Communication | Down-regulation of these chemokine receptors could increase neutrophil adhesion and impair its migration through the glomerular endothelium, contributing to neutrophil accumulation and, in concert with ANCA, persistent inflammation within the vessel wall. | 22152684 |
| Inflammation | Altered Intercellular Communication | Biopsy showed chronic inflammation without any suspicion of malignity. | 22153213 |
| Inflammation, Necrosis, Refractory anemias, Atherosclerosis, Rheumatoid Arthritis | Altered Intercellular Communication | To examine how treatment of rheumatoid arthritis (RA) with anti-tumour necrosis factor alpha antagonists (anti-TNF) and B-cell targeting rituximab influences novel markers of atherosclerosis and inflammation, such as atheroprotective natural IgM antibodies against phosphorylcholine (anti-PC), oxidised low-density lipoprotein (oxLDL) and apolipoproteins. | 22153361 |
| Inflammation, Atherosclerosis | Altered Intercellular Communication | Body fat percentage as a risk factor for atherosclerosis but not for inflammation for hemodialysis patients: differences between genders. | 22153383 |
| Inflammation, Peripheral Arterial Diseases, Coronary Artery Disease | Altered Intercellular Communication | Serum paraoxonase-3 concentration is associated with insulin sensitivity in peripheral artery disease and with inflammation in coronary artery disease. | 22153698 |
| Inflammation, atherosclerotic | Altered Intercellular Communication | In both atherosclerotic phenotypes, serum PON3 concentration was increased, but this was associated with decreased insulin sensitivity in PAD and with inflammation in CAD. | 22153698 |
| Autoimmune Diseases, Inflammation, Lupus Erythematosus, Lupus Erythematosus, Systemic | Altered Intercellular Communication | Systemic lupus erythematosus (SLE), a prototypical autoimmune disease, often results in comorbidities from exposure to medications as well as from chronic inflammation. | 22153881 |
| Irritation - emotion, Inflammation, Muscle hypertrophy, Necrosis | Altered Intercellular Communication | Based on our patient material, we suggest that chronic nerve irritation, such as compression, can lead to muscle hypertrophy which, when prolonged, provokes fibre necrosis and secondary inflammation. | 22153989 |
| Inflammation, "Brodies abscess | Altered Intercellular Communication | Although microbiologic analysis of the surgical specimen failed to reveal a causative microorganism, histopathologic inspection showed chronic inflammation, consistent with Brodie's abscess. | 22154059 |
| Crohn Disease, Colorectal Carcinoma, Ulcerative Colitis | Altered Intercellular Communication | Inflammatory processes, including, specifically, the inflammatory conditions Crohn's disease (CD) and ulcerative colitis (UC) predispose to colorectal cancer. | 22154103 |
| Chronic disease | Altered Intercellular Communication | Inflammation increases with age and is associated with many chronic diseases that are prevalent among older adults. | 22155500 |
| Inflammation, Bacterial Infections | Altered Intercellular Communication | Persistent pathogens such as latent herpesviruses and chronic bacterial infections can act as a source of inflammation. | 22155500 |
| Inflammation | Altered Intercellular Communication | EBV and CMV replication can induce proinflammatory cytokine production and thus could influence systemic inflammation. | 22155500 |
| Inflammation | Altered Intercellular Communication | Thus, reactivation of multiple herpesviruses may drive inflammation and could contribute to poorer health among older adults. | 22155500 |
| Crohn Disease | Altered Intercellular Communication | Inflammation profile of four early onset Crohn patients. | 22155628 |
| Inflammation, Prediabetes syndrome, Gingival Hemorrhage | Altered Intercellular Communication | Self-perceived gingival bleeding and clinical periodontal inflammation were severe in patients with prediabetes as compared with controls. | 22157389 |
| Prediabetes syndrome | Altered Intercellular Communication | Comparison of self-perceived oral health, periodontal inflammatory conditions and socioeconomic status in individuals with and without prediabetes. | 22157389 |
| Inflammation, Intradermal Route of Drug Administration | Altered Intercellular Communication | Use of CF to adjust for inflammation increased the prevalence of ID based on ferritin < 12 mg/L by 34% (from 27 to 41%). | 22157541 |
| Inflammation, Intradermal Route of Drug Administration | Altered Intercellular Communication | Although the use of CF to adjust for inflammation appears indicated, further work is needed to confirm that this approach improves the accuracy of assessment of ID. | 22157541 |
| Inflammation, Atherosclerosis | Altered Intercellular Communication | The mechanism linking inflammation to atherosclerosis is unknown. | 22157685 |
| Inflammation, Cardiovascular Diseases, Interferon-Related DNA Damage Resistance Gene Signature, Coronary Artery Disease, Inflammatory disorder | Altered Intercellular Communication | We have previously demonstrated a high occurrence of inflammation in the aortic adventitia of patients with coronary artery disease (CAD), which was more pronounced in patients with inflammatory rheumatic diseases (IRDs), and which might be involved in the pathogenesis of cardiovascular disease. | 22157685 |
| vascular inflammations, Infection, Atherosclerosis | Altered Intercellular Communication | In theory, infections might play a role in the pathogenesis of vascular inflammation or atherosclerosis, or both. | 22157685 |
| immunoglobulin A | Altered Intercellular Communication | Mycoplasma IgA was related to a lower occurrence of aortic adventitial inflammation. | 22157685 |
| Communicable Diseases, Fasciitis, Inflammation, Necrosis | Altered Intercellular Communication | Necrotising fasciitis is an uncommon but life-threatening soft tissue infection characterised by rapidly spreading inflammation and necrosis of skin, subcutaneous fat and fascia. | 22157919 |
| Inflammation, Benign prostatic hypertrophy | Altered Intercellular Communication | Influence of immune inflammation on androgen receptor expression in benign prostatic hyperplasia tissue. | 22157983 |
| Inflammation, Benign prostatic hypertrophy | Altered Intercellular Communication | This study was designed to investigate the association between immune inflammation and androgen receptor (AR) expression in benign prostatic hyperplasia (BPH). | 22157983 |
| Inflammation | Altered Intercellular Communication | An immune inflammation score for each specimen was defined by combining three immunohistochemical markers (CD4, CD8 and CD20). | 22157983 |
| Inflammation | Altered Intercellular Communication | Total prostate volume (TPV) was higher in the immune inflammation group than in the non-immune inflammation group (62.7 ml vs. 49.2 ml, t=2.482, P<0.05). | 22157983 |
| Inflammation | Altered Intercellular Communication | Patients in the immune inflammation group had a higher serum prostate-specific antigen (PSA) than those in the non-inflammation group (7.5 ng ml(-1 )vs. 5.4 ng ml(-1), t=2.771, P<0.05). | 22157983 |
| Inflammation | Altered Intercellular Communication | Specifically, the immune inflammation group showed a higher rate of AR expression than the non-inflammation group (56.1% vs. 28.2%, kh(2)=7.665, P<0.05). | 22157983 |
| Lung diseases, Malignant Neoplasms | Altered Intercellular Communication | Solitary pulmonary nodules can represent different specific lung diseases, focal non-specific inflammations, and primary and secondary malignant tumours. | 22159242 |
| Inflammation, Anterior Ischemic Optic Neuropathy | Altered Intercellular Communication | Cellular inflammation in nonarteritic anterior ischemic optic neuropathy and its primate model. | 22159678 |
| Infarction, Inflammation | Altered Intercellular Communication | Cellular inflammation plays a major early role following white-matter (optic nerve) infarct, with both polymorphonuclear leukocyte and macrophage function involved in debris elimination and tissue remodeling. | 22159678 |
| Inflammation, Optic Neuropathy | Altered Intercellular Communication | The optic nerve in NAION and its primate model are associated with early cellular inflammation, previously unsuspected, that may contribute to postinfarct optic nerve damage. | 22159678 |
| Inflammation, Bronchiolitis | Altered Intercellular Communication | Airway IFN-g production during RSV bronchiolitis is associated with eosinophilic inflammation. | 22160185 |
| Inflammation, Bronchiolitis | Altered Intercellular Communication | These results suggest that IFN-g may play an important role in eosinophilic inflammation in RSV bronchiolitis. | 22160185 |
| Inflammation, ETV3 wt Allele | Altered Intercellular Communication | The present results show that the PC1 score is closely associated with parameters of MetS, inflammation and insulin resistance. | 22160241 |
| Inflammation, Crohn Disease | Altered Intercellular Communication | Computed tomography enterography (CTE) may detect the presence, severity, and extent of bowel inflammation in patients with Crohn's disease (CD). | 22160373 |
| Inflammation | Altered Intercellular Communication | CTE-WE represents a comprehensive imaging technique which may demonstrate bowel inflammation and CD extraintestinal manifestations. | 22160373 |
| Inflammation, Neoplasms | Altered Intercellular Communication | Thus, further appraisal of this novel method with inclusion of different tumour entities, systemic conditions and inflammation in a larger study population appears highly valuable. | 22160580 |
| Inflammation | Altered Intercellular Communication | Persistent H. pylori infection may affect the mucosal expression profiles of miRNAs via chronic inflammation mediated by proinflammatory cytokines. | 22161133 |
| Inflammation | Altered Intercellular Communication | This involves inflammation, epidermal differentiation, lipid metabolism, cell signalling and adhesion in response to FLG-dependent skin-barrier dysfunction. | 22164253 |
| Inflammation, myocardial injury | Altered Intercellular Communication | Does tight glucose control prevent myocardial injury and inflammation? | 22164453 |
| Communicable Diseases, Inflammation, Traumatic injury | Altered Intercellular Communication | There was no history of trauma, inflammation, or infection, and no significant urologic history. | 22165050 |
| Inflammation | Altered Intercellular Communication | Ferritin-based diagnosis of iron deficiency in these patients is a challenging task, as serum ferritin level may be high due to chronic inflammation and mask iron deficiency. | 22165676 |
| Inflammation, Kidney Failure | Altered Intercellular Communication | This study showed measurement of serum ferritin in the presence of chronic inflammation induced by renal failure cannot be a credible indicator of body iron supply, while under this certain condition serum transferrin receptor can more appropriately reflect the amount of body iron supply. | 22165676 |
| Inflammatory Bowel Diseases, Inflammation, Chronic disease | Altered Intercellular Communication | Inflammatory bowel disease (IBD) represents a heterogeneous group of chronic disorders characterized by inflammation of gastrointestinal tract, typically with a relapsing and remitting clinical course of unknown etiology. | 22166284 |
| Inflammation | Altered Intercellular Communication | The pathogenesis of IPEH might be related to inflammation or mechanical stimulus such as irritation. | 22167033 |
| Tuberculoma, Granulomatous inflammation | Altered Intercellular Communication | At surgery, a nodular, avascular lesion was found and pathological examination confirmed granulomatous inflammation suspecting tuberculoma. | 22167292 |
| Inflammation, Postoperative Period | Altered Intercellular Communication | Supra-physiological rhBMP loads during spinal fusion may trigger local inflammation and post-operative radiculitis. | 22167451 |
| Inflammation, Diabetes Mellitus, Non-Insulin-Dependent, Cardiovascular Diseases | Altered Intercellular Communication | This distribution is associated with an increased risk of type 2 diabetes and cardiovascular disease that are linked to low-grade inflammation. | 22168600 |
| Refractory anemias, Inflammation, Rheumatoid Arthritis | Altered Intercellular Communication | Advanced glycation end products (AGEs) are produced and can accumulate during chronic inflammation, as might be present in patients with rheumatoid arthritis (RA). | 22168993 |
| Ultraviolet B radiation, Inflammation, Age related macular degeneration, methyldopa | Altered Intercellular Communication | Ultraviolet B (UVB) radiation may cause the inflammation of retinal pigment epithelium (RPE) cells and play a role in development of age-related macular degeneration (AMD). | 22169226 |
| APP gene, Inflammation, Aneurysm | Altered Intercellular Communication | The purpose of the present study was to investigate the relationship between systemic expression of biomarkers of inflammation and extracellular matrix remodeling and aneurysm size in AAA patients. | 22169593 |
| Inflammation, Bacterial Infections | Altered Intercellular Communication | Further studies are warranted whether hantaviruses are setting the stage for a secondary bacterial infection or cause an inflammation itself. | 22169597 |
| Intraocular inflammation, Lesion of conjunctiva | Altered Intercellular Communication | In both cases, incomplete excision of conjunctival SCC was followed by rapid regrowth of the conjunctival lesion and signs of intraocular inflammation. | 22169876 |
| Inflammation, Endothelial Cells, Edema, Keratomileusis, Laser In Situ | Altered Intercellular Communication | To report a case of severe interface inflammation, flap edema, and endothelial cell loss after laser-assisted in situ keratomileusis (LASIK). | 22169878 |
| Inflammation | Altered Intercellular Communication | Evolutionarily conserved functions of PlGF-1 for placental phenomena are obviously also present in synovial inflammation. | 22170453 |
| Inflammation | Altered Intercellular Communication | Regenerative potential of human muscle stem cells in chronic inflammation. | 22171690 |
| Inflammation | Altered Intercellular Communication | Chronic inflammation is a profound systemic modification of the cellular microenvironment which could affect survival, repair and maintenance of muscle stem cells. | 22171690 |
| Inflammation, Muscle (organ) | Altered Intercellular Communication | The aim of this study was to define the role of chronic inflammation on the regenerative potential of satellite cells in human muscle. | 22171690 |
| Refractory anemias, Inflammation, Rheumatoid Arthritis, Degenerative polyarthritis | Altered Intercellular Communication | As a model for chronic inflammation, 11 patients suffering from rheumatoid arthritis (RA) were included together with 16 patients with osteoarthritis (OA) as controls. | 22171690 |
| Refractory anemias, Inflammation | Altered Intercellular Communication | In the present study we found evidence that chronic inflammation in RA does not affect the in vitro regenerative potential of human satellite cells. | 22171690 |
| Inflammation, Virus Diseases, Septic Shock | Altered Intercellular Communication | Viral infections in septic shock (VISS-trial)-crosslinks between inflammation and immunosuppression. | 22172138 |
| Neurogenic Inflammation, Complex Regional Pain Syndromes | Altered Intercellular Communication | There is evidence demonstrating that neurogenic inflammation and activation of the immune system play a significant role in the pathophysiology of CRPS. | 22172450 |
| Inflammation, Calcification of coronary artery | Altered Intercellular Communication | Association of systemic inflammation markers with the presence and extent of coronary artery calcification. | 22172511 |
| Inflammation, Hepatobiliary Disorder | Altered Intercellular Communication | TLR4-positive hepatic progenitor cells and interlobular bile ducts were significantly correlated with the stage of liver disease (P<0.001), the grade of inflammation (P<0.001), and the activity of portal/septal myofibroblasts (P<0.001). | 22173288 |
| Inflammation, Fibrosis Assessment | Altered Intercellular Communication | TLR4 expression positively correlated with fibrosis (P<0.05) and inflammation (P<0.05). | 22173288 |
| Inflammation, Neoplasms | Altered Intercellular Communication | We conclude that MR imaging patterns can be possible manifestations of intravascular-dominant infiltration by tumor cells with associated occlusion or inflammation, depending on the level of affected vessels. | 22173763 |
| Inflammation | Altered Intercellular Communication | Galectins are a family of b-galactoside-binding proteins; by binding various glycoproteins, they play important roles in the regulation of cellular functions in inflammation and immunity. | 22173878 |
| Inflammation, Heart failure | Altered Intercellular Communication | Markers of inflammation are associated with increased risk of heart failure, but data on differential white blood cell (WBC) count are lacking. | 22173908 |
| Inflammation, Heart failure | Altered Intercellular Communication | Inflammation as measured by WBC count was independently associated with incident heart failure in apparently healthy men but not women. | 22173908 |
| Inflammation, CDISC SDTM Lesion Complexity Terminology | Altered Intercellular Communication | Factorial structure change during healthy ageing was associated with a decrease in complexity but showed an increase in variability and inflammation. | 22174010 |
| Weakness, Hypercalcemia, CTCAE, Hypokalemia, Epigastric pain, Anorexia, Nausea, Hypomagnesemia, Fatigue | Altered Intercellular Communication | This ECG concerns a 60-year-old male presented with general fatigue, weakness, epigastric pain, anorexia, nausea and extreme hypercalcemia (serum total and ionized calcium levels 20.5 mg/dL and 12.02 mg/dl, respectively), hypokalemia and hypomagnesemia associated with elevated parathyroid hormone (1160 pg/ml) and normal serum vitamin D level (97 ng/ml) . | 22174173 |
| Inflammation, Rheumatoid Arthritis, Dyslipidemias | Altered Intercellular Communication | Apolipoprotein E gene polymorphisms are strong predictors of inflammation and dyslipidemia in rheumatoid arthritis. | 22174202 |
| Refractory anemias, Inflammation, Dyslipidemias | Altered Intercellular Communication | Dyslipidemia in RA may be driven by inflammation and genetic factors. | 22174202 |
| Refractory anemias, Inflammation | Altered Intercellular Communication | We compared the frequency of 2 ApoE single-nucleotide polymorphisms (SNP) in patients with RA and controls, and studied the relationship of ApoE genotypes with lipids and inflammation in RA. | 22174202 |
| Refractory anemias, Inflammation | Altered Intercellular Communication | ApoE genotypes are strongly linked to inflammation and lipid levels in RA, raising interest in the prognostic implications of ApoE genotypes. | 22174202 |
| Inflammation | Altered Intercellular Communication | Fatty acid binding protein 4 (FABP4) has been shown to play an important role in macrophage cholesterol trafficking and associated inflammation. | 22174896 |
| Retinal Detachment, Inflammation, Nerve Degeneration | Altered Intercellular Communication | This systematic analysis confirmed the occurrence of both neurodegeneration and inflammation during retinal detachment, and further identifies precisely the modification of expression of the different genes implicated in these two phenomena. | 22174898 |
| Retinal Detachment, Inflammation, Photoreceptors | Altered Intercellular Communication | Our data henceforth give a new insight into the disease process and provide a rationale for therapeutic strategies aimed at limiting inflammation and photoreceptor damage associated with retinal detachment and, in turn, improving visual prognosis after retinal surgery. | 22174898 |
| Cartilage destruction, Inflammation, Retinitis Pigmentosa, polychondritis | Altered Intercellular Communication | relapsing polychondritis (RP) is a rare multisystem disease of unknown etiology, characterized by recurrent episodes of inflammation and cartilage destruction. | 22176820 |
| Inflammation, Carcinogenesis | Altered Intercellular Communication | The nuclear factor k-light-chain enhancer of activated B-cells (NF-kB) signaling pathway is regarded as an important factor in inflammation and carcinogenesis. | 22176836 |
| Inflammation | Altered Intercellular Communication | Total self-reported weekday sitting time was associated with biomarkers linked to chronic low-grade inflammation and poor metabolic health in women, but not men, independent of physical activity. | 22176839 |
| Inflammation, Sedentary lifestyle, Atherosclerosis | Altered Intercellular Communication | Sedentary behavior and adiposity-associated inflammation: the Multi-Ethnic Study of Atherosclerosis. | 22176840 |
| Inflammation | Altered Intercellular Communication | To determine the associations between sedentary behavior and measures of adiposity-associated inflammation. | 22176840 |
| Inflammation, Sedentary lifestyle | Altered Intercellular Communication | Sedentary behavior is associated with unfavorable levels of adiposity-associated inflammation. | 22176840 |
| ARCN1 gene, Inflammation, Pulmonary Emphysema, Osteoporosis | Altered Intercellular Communication | Disturbance of the OPG/RANK/RANKL pathway and systemic inflammation in COPD patients with emphysema and osteoporosis. | 22176920 |
| Inflammation | Altered Intercellular Communication | Analysis supported selective up-regulation of genes in the Hunner lesion interstitial cystitis/bladder pain syndrome group (hypothesis 3), which were primarily associated with inflammation. | 22177197 |
| Encephalopathy, CTCAE 5.0, White matter lesions, Neoplasms, Mitochondrial encephalopathy, Communicable Diseases, Venous Thrombosis, Demyelinating Diseases, Glioblastoma Multiforme Pathway, vascular inflammations | Altered Intercellular Communication | Among them, mitochondrial encephalopathy and vein thrombosis lesions located in the cortex; metastatic tumor and blood-borne infection mainly involving junction of grey and white matter; glioma, radiation encephalopathy and demyelinating disease include white matter lesions; vascular inflammation showed cortical and subcortical white matter lesions. | 22177243 |
| Granulomatous inflammation, Sarcoidosis | Altered Intercellular Communication | Among the various renal manifestations of sarcoidosis, granulomatous inflammation confined to the tubulointerstitial compartment is the most commonly reported finding. | 22177616 |
| Necrotizing granulomatous inflammation, Interstitial inflammation, Granulomatous Angiitis | Altered Intercellular Communication | Kidney biopsy showed diffuse interstitial inflammation with noncaseating granulomas that exhibited the unusual feature of infiltrating the walls of small arteries with destruction of the elastic lamina, consistent with granulomatous vasculitis. | 22177616 |
| Pain Distress Question, Inflammation | Altered Intercellular Communication | Further studies are warranted to elucidate the relation between bE and pain thresholds secondary to stress, inflammation, and discectomy. | 22177809 |
| Ischemia, Inflammation | Altered Intercellular Communication | Following ischemia, inflammation is provoked and related to the clinical outcomes. | 22178059 |
| Inflammation, Data types - Address | Altered Intercellular Communication | In conclusion, our study provides evidence for the first time that the functionality of HDL is impaired in AD and that this alteration might be caused by AD-associated oxidative stress and inflammation. | 22178419 |
| Inflammation, Pain Distress Question | Altered Intercellular Communication | The changes in total reaction moments and GRFs for only the NSAID suggest that greater increases in joint loading occurs when joint inflammation is treated in addition to pain. | 22179861 |
| Inflammation | Altered Intercellular Communication | It is associated with an unusual growth of fibrotic tissue admixed with varying amounts of inflammation that displaces and compresses normal anatomic structures, resulting in dysfunction. | 22180112 |
| Squamous cell carcinoma of the head and neck | Altered Intercellular Communication | Clinical observations and epidemiologic studies suggest that the incidence of head and neck squamous cell carcinoma (HNSCC) correlates with dental hygiene, implying a role for bacteria-induced inflammation in its pathogenesis. | 22180460 |
| Inflammation, Squamous cell carcinoma of the head and neck, Neoplasms | Altered Intercellular Communication | Methylation analysis in four genes (MDR1, IL8, RARB, TGFBR2) previously linked to HNSCC or inflammation shows significantly increased methylation in tumor samples compared with normal oral mucosa. | 22180460 |
| Inflammation, Depressed mood | Altered Intercellular Communication | As there are few studies on inflammatory markers that distinguish between depressed and nondepressed smokers, it is unclear if there is a cumulative impact of these mediators of inflammation. | 22180575 |
| Inflammation | Altered Intercellular Communication | However, an increased (18)FDG-tracer uptake at the thickened anterior leaflet indicated active inflammation. | 22180605 |
| Inflammation, Bioprosthesis device | Altered Intercellular Communication | In conclusion, our case indicates that (18)FDG-PET with cardiac CT image fusion may be a useful tool in patients with unclear focus of inflammation and possible bioprosthesis infection. | 22180605 |
| Sepsis, Inflammation, Abnormality of mitochondrial metabolism, cell injury | Altered Intercellular Communication | A plasmatic factor such as nitric oxide, increased in inflammation and able to induce mitochondrial dysfunction, oxidative stress and apoptosis, may be responsible for cell damage in sepsis. | 22180620 |
| Corneal stromal opacities, Conjunctivitis | Altered Intercellular Communication | The two groups also did not differ in terms of corneal opacification, visual acuity, conjunctival inflammation, and surgical complications. | 22180732 |
| Inflammation, Periodontitis, Chronic Kidney Diseases, Chronic inflammatory disorder | Altered Intercellular Communication | BACKGROUND AND OBJECTVE: Chronic inflammatory diseases have been investigated as a possible source of inflammation in chronic kidney disease patients; however, there is a shortage of information about the prevalence of periodontitis in such individuals. | 22181057 |
| Inflammation, Thickened | Altered Intercellular Communication | Nodules, thickening and inflammation were the most common in the videolaryngoscopy exams. | 22183280 |
| Inflammation, Thickened | Altered Intercellular Communication | Laryngeal lesions were found in the videolaryngoscopy exams, stressing nodules, thickening and inflammation. | 22183280 |
| Inflammation, Pulmonary Emphysema | Altered Intercellular Communication | Data were correlated with body composition, emphysema and systemic inflammation. | 22183483 |
| ARCN1 gene, Inflammation, Chronic Obstructive Airway Disease | Altered Intercellular Communication | Chronic obstructive pulmonary disease (COPD) is associated with pulmonary and systemic inflammation. | 22183488 |
| Refractory anemias, Inflammation | Altered Intercellular Communication | A US score was designed to determine the degree of inflammation in the shoulder, the elbow, the hip, and the knee joint in patients with RA (Sonography of Large Joints in Rheumatology [SOLAR] score). | 22183834 |
| Airway structure, Inflammation, Arthritis, Refractory anemias | Altered Intercellular Communication | Airways abnormalities that are consistent with inflammation are common in autoantibody-positive subjects without inflammatory arthritis and are similar to airways abnormalities seen in patients with early RA. | 22183986 |
| Refractory anemias, Pneumonitis | Altered Intercellular Communication | Further studies are needed to define the mechanistic role of lung inflammation in the development of RA. | 22183986 |
| Natriuresis | Altered Intercellular Communication | Activation of hormonal changes that regulate depressor responses to salt depletion may not have occurred with the 3-hour natriuresis of the short protocol. | 22184320 |
| Communicable Diseases, Inflammation | Altered Intercellular Communication | Reduced inflammation and altered innate response in neonates during paramyxoviral infection. | 22185352 |
| Inflammation | Altered Intercellular Communication | Importantly, the expression of the RIG-I-like receptors (RLRs) was delayed in the neonatal mice, which might have contributed to their reduced inflammation and differential cytokine expression. | 22185352 |
| Pneumonitis | Altered Intercellular Communication | Neonatal mice developed similar SeV titers and cleared the virus with similar efficiency despite developing a dramatically lower degree of pulmonary inflammation compared to adults. | 22185352 |
| Inflammation | Altered Intercellular Communication | This suggests that inflammation in the lung may not be required to control viral replication. | 22185352 |
| Gastrointestinal inflammation, Ulcerative Colitis | Altered Intercellular Communication | This study demonstrates that TLR2, TLR4, TLR8, and TLR9 expression increases in active UC patients, and that the mRNA levels positively correlate with the severity of intestinal inflammation as well as with inflammatory cytokines. | 22185629 |
| Multiple Myeloma, Hypercalcemia, CTCAE | Altered Intercellular Communication | A case of myeloma with hypercalcemia caused by high serum concentrations of both parathyroid hormone-related peptide (PTHrP) and macrophage inflammatory protein-1a (MIP-1a). | 22185991 |
| Inflammation, Takayasu Arteritis, Arteritis | Altered Intercellular Communication | Surgical repair of these lesions can be compromised by the chronic inflammation of Takayasu's arteritis. | 22186452 |
| Psoriasis, Psoriasiform lesion | Altered Intercellular Communication | Psoriasis and psoriasiform lesions were documented in 7 patients diagnosed with different rheumatic inflammatory conditions (1.56%). | 22187056 |
| Inflammation, Atrial Fibrillation by ECG Finding | Altered Intercellular Communication | Increasing evidence supports a role for inflammation in promoting atrial fibrillation (AF) and statins have anti-inflammatory effects that may be relevant for the prevention of AF. | 22187510 |
| Inflammation, Ulcerative Colitis | Altered Intercellular Communication | Long-term outcome of patients with distal ulcerative colitis and inflammation of the appendiceal orifice. | 22187699 |
| Inflammation, Ulcerative Colitis | Altered Intercellular Communication | Skip inflammation of the appendiceal orifice has been described in distal UC (UC-IAO) but long-term clinical outcomes are poorly established. | 22187699 |
| Hepatic inflammation, Hepatitis | Altered Intercellular Communication | These results suggest that the reduced expression of B7-H3 in the livers might temper the inhibition of T-cell responses mediated by B7-H3 expressed on hepatocytes and thus promote the hepatic inflammation and hepatitis progression in the chronic HBV-infected patients. | 22187944 |
| Inflammation, Dental Plaque | Altered Intercellular Communication | Oral hygiene was registered with Mucosal-Plaque Score, an index based on assessment of plaque accumulation and mucosal/gingival inflammation. | 22187971 |
| Inflammation, Fracture, Bipolar Disorder | Altered Intercellular Communication | Results from these exploratory analyses support a role for inflammation in the pathophysiology of depressive symptoms after hip fracture. | 22188073 |
| Attention deficit hyperactivity disorder, Sleep disturbances | Altered Intercellular Communication | The high rate of occurrence of sleep disturbances in children with attention-deficit/hyperactivity disorder (ADHD) prompted the idea that structural and neurotransmitter changes might give rise to specific sleep pattern abnormalities. | 22188114 |
| Inflammation, Cerebral Infarction, Vasculitis, CTCAE | Altered Intercellular Communication | Multiple cerebral infarcts with a few vasculitic lesions in the chronic stage of cerebral amyloid angiopathy-related inflammation. | 22188118 |
| Cerebral Amyloid Angiopathy, Inflammation | Altered Intercellular Communication | We report a 75-year-old man with a 3.5-year history of cerebral amyloid angiopathy (CAA)-related inflammation. | 22188118 |
| Vasculitis, CTCAE | Altered Intercellular Communication | In conclusion, we consider that, although the association of PR3-ANCA with the pathogenesis of Ab-associated vasculitis remained unclear, the present case represents a rare example of CAA-related inflammation at the chronic stage. | 22188118 |
| Inflammation, atherosclerotic | Altered Intercellular Communication | Our understanding of chronic inflammation in CKD-5D and of its influence in the accelerated atherosclerotic process has greatly evolved. | 22188694 |
| Hypernatremia, Inflammation, Electrocardiogram: left ventricle hypertrophy (finding), Anemia | Altered Intercellular Communication | There is sufficient evidence to indicate that on-line hemodiafiltration has the potential to improve chronic inflammation, fluid overload, left ventricular hypertrophy, anemia and quality of life of CKD-5D patients. | 22188694 |
| Inflammation, Italy, Anemia | Altered Intercellular Communication | Here, we intend to present new insights obtained from a prospective observational study (RISCAVID, 'RISchio CArdiovascolare nei pazienti afferenti all'Area Vasta In Dialisi') performed on a large HD population in the northwestern region of Tuscany, Italy, on the assessment of the different parameters of chronic inflammation and gross/CV mortality and anemia management. | 22188694 |
| Impaired cognition, millicurie | Altered Intercellular Communication | Acetylcholine, the main neurotransmitter of the parasympathetic system may be deficient in mild cognitive impairment (MCI). | 22188719 |
| Inflammation, Intermittent fever (finding) | Altered Intercellular Communication | Incomplete Kawasaki disease with intermittent fever and retropharyngeal inflammation. | 22189530 |
| Inflammation, Coronary Artery Disease | Altered Intercellular Communication | Abundant evidence supports the hypothesis that inflammation plays an important role in the development of coronary artery disease (CAD). | 22189538 |
| Inflammation, Benign prostatic hypertrophy, Prostate carcinoma, Neoplasms | Altered Intercellular Communication | Serum levels of secreted group IIA phospholipase A(2) in benign prostatic hyperplasia and prostate cancer: a biomarker for inflammation or neoplasia? | 22189868 |
| Inflammation, Structure of posterior cerebral artery | Altered Intercellular Communication | In conclusion, these findings suggest that cancer-related changes are not exclusive factors contributing to elevated serum sPLA(2)-IIA levels and emphasize the utility of sPLA(2)-IIA as a circulating marker of inflammation in patients with BPH and PCa. | 22189868 |
| Inflammation, Necrosis, Fibrosis Assessment, Hyperplastic Polyp, Retractile Mesenteritis | Altered Intercellular Communication | I can be evaluated as a single disease with two pathological subgroups: MP, representing the very large majoritary subgroup where inflammation and fat necrosis predominate and Retractile Mesenteritis, rarely found, where fibrosis and retraction predominate. | 22191288 |
| Mesenteric Panniculitis, Hyperplastic Polyp | Altered Intercellular Communication | Mesenteric panniculitis (MP) is an uncommon benign inflammatory condition of unknown etiology that involves the adipose tissue of the mesentery. | 22191288 |
| Inflammation, Necrosis | Altered Intercellular Communication | A thoracoscopic lung biopsy of the upper left lobe revealed necrosis of lung tissue, with acute and chronic inflammation of the cavity wall and the presence of hyphae consistent with Aspergillus species. | 22191319 |
| Inflammation, dendritic lamellar body, Data types - Address | Altered Intercellular Communication | Correlations between HA levels and markers of inflammation and vascular changes were only detected in female AD patients but in both male and female DLB patients. | 22191565 |
| Airway structure, Wheezing | Altered Intercellular Communication | We demonstrated that 5 yr old children with persistent wheeze already had elevated exhaled inflammatory markers at preschool age compared to never wheezers, indicating augmented airway inflammation in these children. | 22192238 |
| Inflammation, Congestive heart failure | Altered Intercellular Communication | Diffuse inflammation is also prominent in CHF and a potent inhibitor of erythrocyte production. | 22192286 |
| Inflammation, Dysplasia, Carcinoma, Communicable Diseases, Squamous metaplasia | Altered Intercellular Communication | Chronic irritation, inflammation, and infection induce squamous metaplasia of the renal collecting system, which may progress to dysplasia and carcinoma in most of affected individuals. | 22192451 |
| Congenital Abnormality | Altered Intercellular Communication | We hypothesize whether transient arterial wall abnormalities, postpartum hormonal changes or subtle connective tissue aberrations play a similar role in the pathogenesis of these two associated conditions. | 22192555 |
| Inflammation, Observation Method - Coagulation, TYPHUS | Altered Intercellular Communication | Coagulation and inflammation in scrub typhus and murine typhus--a prospective comparative study from Laos. | 22192733 |
| Inflammation, Observation Method - Coagulation | Altered Intercellular Communication | The current understanding of coagulation and inflammation in the pathogenesis of these clinically very similar vasculotropic diseases is limited. | 22192733 |
| Inflammation, Damage | Altered Intercellular Communication | Functional mutations in the genes related to innate immune response exacerbate mucosal damage coupled with persistent inflammation. | 22192785 |
| Inflammation, Hydrarthrosis | Altered Intercellular Communication | To investigate which knee and probe position best identifies knee inflammation and to determine a cut-off level for abnormal synovial effusion. | 22194046 |
| Necrotizing granulomatous inflammation, Infectious Lung Disorder, Bronchiectasis | Altered Intercellular Communication | Bronchiectasis with cavity formation and necrotizing bronchocentric granulomatous inflammation predominated but extrapulmonary infection was absent. | 22194586 |
| Granulomatous inflammation | Altered Intercellular Communication | Miliary nodules and/or consolidation with poorly formed granulomatous inflammation were noted in the three disseminated patients with mycobacterial lung involvement. | 22194586 |
| Chronic inflammation | Altered Intercellular Communication | Excluding recent smoking is therefore important in clinical studies with chronic inflammation as primary focus. | 22194931 |
| Inflammation, Obesity, Diabetes Mellitus | Altered Intercellular Communication | Recent studies have suggested that mast-cell activation and inflammation are important in obesity and diabetes. | 22194960 |
| Dryness of eye, Conjunctivitis | Altered Intercellular Communication | RAG1KO recipients of adoptively transferred CD4+T cells isolated from DS5 CD4-DNTGFbRII showed milder dry eye phenotype and less conjunctival inflammation than recipients of WT control. | 22194977 |
| Inflammation, Primary malignant neoplasm | Altered Intercellular Communication | The relationship of these novel candidate biomarkers with cancer and inflammation suggests that they are truly associated with HL and therefore may be useful for the early detection of this cancer in susceptible populations. | 22195036 |
| Inflammation, Vegetation | Altered Intercellular Communication | The infected valve did not show vegetations or perforations, but histiocytic inflammation was seen along the endocardial surfaces of the valve. | 22196518 |
| SLC5A8 wt Allele, Cardiac dysfunction | Altered Intercellular Communication | AIT effectively improves oxygen uptake efficiency by enhancing cerebral/muscular hemodynamics and suppresses oxidative stress/inflammation associated with cardiac dysfunction, and also promotes generic/disease-specific qualities of life in patients with HF. | 22197120 |
| Inflammation, Corneal Ulcer, corneal melt | Altered Intercellular Communication | Two male patients, 80 and 60 years old, with persistent corneal ulcerations, corneal melting, and inflammation some months after an LS episode. | 22197436 |
| Inflammation, Metabolic Syndrome X, Cardiovascular Diseases | Altered Intercellular Communication | Inflammation and oxidative stress plays a critical role in cardiovascular disease and metabolic syndrome often occurs with these two variables. | 22197455 |
| Parkinsonian Disorders | Altered Intercellular Communication | This post-hoc functional analysis identified early-onset changes in Parkinsonian, immune and alternative splicing pathways which shifted into late-onset or exposure-associated NFkB-mediated neuro-inflammation. | 22198569 |
| Stomach Carcinoma | Altered Intercellular Communication | Comparison of the prognostic value of various preoperative inflammation-based factors in patients with stage III gastric cancer. | 22198641 |
| Chronic lymphocytic inflammation, Inflammation, Necrosis | Altered Intercellular Communication | While MRI showed increased signal intensity on T2-weighted images of the leg muscles, indicating inflammation, muscle biopsy found widespread necrosis with only weak and focal lymphocytic infiltration. | 22198662 |
| Inflammation, Necrosis | Altered Intercellular Communication | A repeat MRI showed progression of inflammation, as well as necrotic foci. | 22198662 |
| ARCN1 gene, Inflammation | Altered Intercellular Communication | The association of low bone mineral density with systemic inflammation in clinically stable COPD. | 22198912 |
| ARCN1 gene, Inflammation, Chronic Obstructive Airway Disease, Inflammatory disorder | Altered Intercellular Communication | Chronic obstructive pulmonary disease (COPD) is known to be a systemic inflammatory disease which affects the function of many organs, and the low bone mineral density (BMD) may be the result of systemic inflammation. | 22198912 |
| ARCN1 gene, Inflammation | Altered Intercellular Communication | The aim of the present study was to explore the association of BMD with systemic inflammation in patients with clinically stable COPD. | 22198912 |
| Inflammation, Osteoporosis | Altered Intercellular Communication | The patients were classified according to T scores, and the relationship between BMD with markers of systemic inflammation and that with other osteoporosis risk factors was assessed. | 22198912 |
| ARCN1 gene, Inflammation, Osteoporosis, Osteopenia | Altered Intercellular Communication | As the abnormality of BMD went severer, COPD patients with osteoporosis had significantly higher levels of systemic inflammation than those with either normal BMD or osteopenia. | 22198912 |
| ARCN1 gene, Inflammation | Altered Intercellular Communication | It can be concluded that systemic inflammation is a significantly independent predictor of low BMD in patients with clinically stable COPD. | 22198912 |
| Ocular Hypertension, Embolism, Amniotic Fluid, Inflammation, Keratomileusis, Laser In Situ | Altered Intercellular Communication | This case illustrates that interface fluid syndrome can develop more than 10 years after LASIK, triggered by ocular hypertension and inflammation after intraocular surgery. | 22200509 |
| Inflammatory Bowel Diseases, Inflammation | Altered Intercellular Communication | Neutrophil gelatinase-associated lipocalin (NGAL) in inflammatory bowel disease: association with pathophysiology of inflammation, established markers, and disease activity. | 22200942 |
| Inflammatory Bowel Diseases, Inflammation | Altered Intercellular Communication | Serum NGAL is elevated particularly in active IBD and correlates with established markers of inflammation and disease activity, implicating its role in the pathophysiology of IBD. | 22200942 |
| Inflammation, Infectious Lung Disorder, Bronchiectasis | Altered Intercellular Communication | Radiological progression of bronchiectasis and air trapping was associated with severe CFTR genotype, worsening neutrophilic inflammation and pulmonary infection. | 22201161 |
| Inflammation, Infectious Lung Disorder, Lung diseases | Altered Intercellular Communication | CT-detected structural lung disease identified in infants and young children with CF persists and progresses over 1 year in most cases, with deteriorating structural lung disease associated with worsening inflammation and pulmonary infection. | 22201161 |
| Inflammation | Altered Intercellular Communication | Evidence suggests that immunological response in chronic inflammation is dynamic, oscillating between active immunity and tolerance. | 22201928 |
| Malignant neoplasm of liver, Inflammation | Altered Intercellular Communication | Interactions between the activated lymphocytes and liver cancer cells increased levels of serum a1AG, an inflammation marker, but these levels normalized following the sixth and final administration. | 22202430 |
| Acute inflammation, Colorectal Carcinoma | Altered Intercellular Communication | DKT administration also significantly suppressed postoperative inflammation following surgery for colorectal cancer. | 22202972 |
| Sepsis, Postoperative sepsis, Peritonitis | Altered Intercellular Communication | Pro- and anti-inflammatory cytokine production was investigated in patients with postoperative sepsis, a murine peritonitis model and in vitro to further delineate the interaction of hyper- and hypo-inflammation in sepsis. | 22204813 |
| Inflammation | Altered Intercellular Communication | In 1309 joints that were not clinically involved, US detected signs indicative of joint inflammation in 9% (121/1309). | 22206648 |
| Inflammation, El Salvador | Altered Intercellular Communication | These studies demonstrate that markers of inflammation are upregulated in response to SV distention. | 22206954 |
| Inflammation, Narcolepsy, Dental Plaque | Altered Intercellular Communication | Studies showing an association between the neuropeptide orexin and AD/DLB-related processes such as amyloid-b (Ab)1-42 plaque formation, a-synuclein accumulation and inflammation indicate that orexin might play a pathogenic role similar to the situation in narcolepsy. | 22207004 |
| Gastrointestinal inflammation | Altered Intercellular Communication | Our findings suggest that different immunopathogenetic pathways underlie chronic intestinal inflammation with different clinical expressions. | 22208453 |
| Airway structure | Altered Intercellular Communication | Ventilatory lung function was measured by spirometry and airway inflammation by exhaled nitric oxide (eNO). | 22208751 |
| Inflammation, Muscular Atrophy | Altered Intercellular Communication | Inflammation is the main cause of disease-associated muscle wasting. | 22208783 |
| Inflammation | Altered Intercellular Communication | We hypothesized that NSAID treatment would preserve muscle performance better than antibiotic treatment alone, by reducing infection-associated inflammation and by increasing expression of cytoprotective Hsp. | 22208783 |
| Acute inflammation | Altered Intercellular Communication | Piroxicam improves clinically relevant measures of muscle performance and mobility in geriatric patients hospitalized with acute infection-induced inflammation. | 22208783 |
| Tumor necrosis, Inflammation, Zinc deficiency | Altered Intercellular Communication | Interleukin-6 and tumor necrosis factor-a overproduction was enhanced in old individuals, suggesting the presence of more marked zinc deficiency and chronic inflammation. | 22209006 |
| Inflammation | Altered Intercellular Communication | Evidence suggests that SCD1 activity may be positively associated with inflammation. | 22209225 |
| Inflammation | Altered Intercellular Communication | Overall, SCD1 activity and genetic variation have an important role in modulating the relationship between FA and inflammation in young adults. | 22209225 |
| Inflammation, Melanosis, Hyperplasia, Hemorrhage | Altered Intercellular Communication | There was no inflammation or hemorrhage, and no melanosis or melanocytic hyperplasia in the epithelium. | 22209988 |
| Inflammation, Burn injury | Altered Intercellular Communication | Characterizing the sensation and affective itch dimensions in conjunction with inflammation, burn injury, recovery, scar maturation, medication, and psychological status should better elucidate postburn itch. | 22210065 |
| Inflammatory abnormality of the eye | Altered Intercellular Communication | In this case, a 43-year-old male patient diagnosed with AOSD showed ocular inflammation after withdrawing from corticosteroid treatment. | 22210274 |
| Prostate carcinoma | Altered Intercellular Communication | Androgen deprivation, the cornerstone of treatment for patients with metastatic prostate cancer, has been shown to elicit prostate tissue apoptosis and lymphocytic inflammation. | 22210552 |
| Refractory anemias, Inflammation | Altered Intercellular Communication | The 6-joint ultrasonographic assessment: a valid, sensitive-to-change and feasible method for evaluating joint inflammation in RA. | 22210661 |
| Refractory anemias, Inflammation | Altered Intercellular Communication | A 6-joint US assessment may be a valid, sensitive-to-change and feasible method for evaluating joint inflammation in RA. | 22210661 |
| Inflammation, Keloid, Burn injury, Traumatic injury | Altered Intercellular Communication | Keloid represents an exuberant wound healing response, usually secondary to trauma, inflammation, surgery, or burns. | 22210735 |
| Inflammation, Fever, CTCAE, Myocarditis, CTCAE 5.0 | Altered Intercellular Communication | Patients with myocarditis were younger and more often presented with signs of inflammation such as elevated C-reactive protein and fever. | 22210737 |
| Inflammation | Altered Intercellular Communication | In summary, binding of leukocytes to activated endothelium mediated by the interaction of CD97 with Thy-1 is involved in firm adhesion of PMNC during inflammation and may play a role in the regulation of leukocyte trafficking to inflammatory sites. | 22210915 |
| Inflammation | Altered Intercellular Communication | The number of DMBT1-positive HPCs increased in direct proportion to inflammation severity. | 22211283 |
| Head of pancreas, Perifolliculitis | Altered Intercellular Communication | Whipple specimens from two patients with a pancreatic head mass showed similar follicular inflammation histologically around bile ducts. | 22211284 |
| Pancreaticobiliary Maljunction, Primary sclerosing cholangitis, Autoimmune Pancreatitis, Waldenstrom Macroglobulinemia, Cholangitis | Altered Intercellular Communication | Biliary and pancreatic ductal systems can be involved in several lymphoplasmacytic inflammatory conditions, including primary sclerosing cholangitis, immunoglobulin G (IgG) 4-related cholangitis and autoimmune pancreatitis. | 22211284 |
| mucosa-associated lymphoid tissue, Inflammation, IgG4-Related Sclerosing Disease, Mucosa-Associated Lymphoid Tissue Lymphoma | Altered Intercellular Communication | Making a differential diagnosis of IgG4-related disease from mucosa-associated lymphoid tissue (MALT) lymphoma or any other chronic inflammation is often challenging. | 22211288 |
| Inflammation, IgG4-Related Sclerosing Disease, Mucosa-Associated Lymphoid Tissue Lymphoma | Altered Intercellular Communication | The number of IgG4-positive cells and the ratio of IgG4/IgG-positive cells were higher in patients with IgG4-related disease than in those with MALT lymphoma (P = 0.016; P < 0.001) and other types of inflammation (P < 0.001; P < 0.001). | 22211288 |
| Inflammation, IgG4-Related Sclerosing Disease, Mucosa-Associated Lymphoid Tissue Lymphoma | Altered Intercellular Communication | Regulatory T-cell infiltration was higher in cases of IgG4-related disease than in MALT lymphomas (P < 0.001) and other types of inflammation (P = 0.006). | 22211288 |
| IgG4-Related Sclerosing Disease, Mucosa-Associated Lymphoid Tissue Lymphoma | Altered Intercellular Communication | We investigated 14 cases of IgG4-related disease, nine MALT lymphomas and 12 other chronic inflammations involving the lacrimal gland and orbit. | 22211288 |
| IgG4-Related Sclerosing Disease, Mucosa-Associated Lymphoid Tissue Lymphoma | Altered Intercellular Communication | Ocular adnexal IgG4-related disease: comparative analysis with mucosa-associated lymphoid tissue lymphoma and other chronic inflammatory conditions. | 22211288 |
| Inflammation, Atherosclerosis | Altered Intercellular Communication | Lipoprotein-associated phospholipase A2 (LpPLA2) is a lipoprotein-bound enzyme involved in inflammation and atherosclerosis. | 22211481 |
| Inflammation, Injury of kidney | Altered Intercellular Communication | Neutrophil gelatinase-associated lipocalin is a marker of kidney injury as well as matrix degradation and inflammation and has previously been shown to be increased in HF. | 22211640 |
| Inflammation, Musculoskeletal Pain, Collagen Diseases | Altered Intercellular Communication | Polymyalgia rheumatica (PMR) is a rheumatic disease that is characterized by intense activation of systemic inflammation. | 22211720 |
| Inflammation, Endothelium | Altered Intercellular Communication | Systemic inflammation has been associated with an imbalance between endothelial injury and repair, defined by an increased number of circulating endothelial microparticles (EMPs) and a reduced number of endothelial progenitor cells (EPCs). | 22211720 |
| Inflammation, Endothelium, Musculoskeletal Pain | Altered Intercellular Communication | Polymyalgia rheumatica is associated with a significant imbalance between endothelial injury and repair, which is dependent on the degree of systemic inflammation. | 22211720 |
| Inflammation, Fatty degeneration of heart, Hemorrhage of kidney, Fibrous, Bronchopneumonia | Altered Intercellular Communication | At autopsy chronic inflammation of the thyroid gland, bronchopneumonia, fibrous and fatty heart degeneration and kidney haemorrhagic infarcts were documented. | 22212924 |
| Inflammation, Carotid Stenosis, Coronary Arteriosclerosis, Coronary Artery Disease | Altered Intercellular Communication | In patients with severe carotid stenosis and nonsignificant coronary artery disease, inflammation is associated with atherosclerotic disease activity and a worse prognosis. | 22212968 |
| Pancreatitis, Acute, Inflammation, Observation Method - Coagulation, Single organ dysfunction | Altered Intercellular Communication | Being a central link between inflammation and coagulation, tissue factor (TF) and its inhibitor (TFPI) might be associated with the severity of acute pancreatitis (AP) and the development of organ failure (OF). | 22213026 |
| Fibrosis Assessment, Liver damage, Portal inflammation | Altered Intercellular Communication | Increased HH activity (evidenced by accumulation of HH-ligand-producing cells and HH-responsive target cells) strongly correlated with portal inflammation, ballooning, and fibrosis stage (each P < 0.0001), supporting a relationship between HH-pathway activation and liver damage. | 22213086 |
| Presenile dementia, Inflammation, "Alzheimers Disease | Altered Intercellular Communication | Biomarkers for insulin resistance and inflammation and the risk for all-cause dementia and alzheimer disease: results from the Framingham Heart Study. | 22213409 |
| Presenile dementia, Inflammation, "Alzheimers Disease", Data types - Address | Altered Intercellular Communication | To investigate the contribution of biomarkers of glucose homeostasis (adiponectin, glucose, glycated albumin, and insulin levels) and inflammation (high-sensitivity C-reactive protein and lipoprotein-associated phospholipase A(2) levels) to the risk of developing Alzheimer disease (AD) and all-cause dementia. | 22213409 |
| Inflammation | Altered Intercellular Communication | It has also been shown that ethnicity may be a factor in affecting systemic inflammation, and limited evidence suggests it may influence plasma LC-PUFA composition. | 22215136 |
| Inflammation | Altered Intercellular Communication | Ethnicity did not modify the associations of LC-PUFAs with markers of inflammation or endothelial activation (all P (interaction)>0.05). | 22215136 |
| Alzheimers Disease", Inflammation | Altered Intercellular Communication | Gene expression variation could be almost completely explained by four transcriptional biomarkers that we named BioAge (biological age), Alz (Alzheimer), Inflame (inflammation), and NdStress (neurodegenerative stress). | 22216330 |
| Inflammation, Necrosis | Altered Intercellular Communication | We propose that the underlying initial condition in its pathogenesis is reduced ability of the neonatal gut epithelial cells (NGECs) to clear oxidative stress (OS), and that when such a NGEC population is exposed to enteral feeding, the increased metabolic OS tips the population toward apoptosis, inflammation, bacterial activation, and eventual necrosis. | 22217195 |
| Necrotizing enterocolitis in fetus OR newborn, Inflammation, Necrosis | Altered Intercellular Communication | Reduction in OS clearance consistent with clinical NEC led to senescence, apoptosis, or inflammation, with disruption of tight junctions, but rarely to NGEC necrosis. | 22217195 |
| Necrotizing enterocolitis in fetus OR newborn, Inflammation, Necrosis | Altered Intercellular Communication | Our ABM incorporates known components of NEC and demonstrates that impaired OS management can lead to apoptosis and inflammation of NGECs, rendering the system susceptible to an additional insult involving regionalized mucus barrier failure and TLR-4 activation, which potentiates the necrosis outcome. | 22217195 |
| Granulomatous inflammation, Sarcoidosis | Altered Intercellular Communication | Histopathological examination of skin biopsies showed granulomatous inflammation, suggestive for sarcoidosis. | 22217306 |
| Inflammation, Asthma | Altered Intercellular Communication | These preliminary findings suggest that EMID2_BL1_ht2 may be a susceptibility marker of inflammation of the nasal passages among Korean asthma patients. | 22217332 |
| Orbital Pseudotumor | Altered Intercellular Communication | [Management of orbital inflammation in internal medicine: a retrospective case series of 29 patients]. | 22217923 |
| Inflammation, Orbital Pseudotumor | Altered Intercellular Communication | To describe a case series of patients investigated in internal medicine for an inflammation of the orbit and to clarify the clinical and pathological features of patients with idiopathic orbital inflammatory syndrome (IOIS). | 22217923 |
| Inflammation, Aplasia of the parotid gland | Altered Intercellular Communication | Recurrent inflammation of accessory parotid tissue associated with unilateral parotid gland aplasia: diagnostic and therapeutic implications. | 22218848 |
| Inflammation, Fatty Liver Disease | Altered Intercellular Communication | NASH patients presented a weak negative correlation between lobular inflammation and Bcl-2 levels. | 22219597 |
| Pain Distress Question, Inflammation, Degenerative polyarthritis, Functional Disability, Impaired | Altered Intercellular Communication | Knee osteoarthritis (KOA), the most common type of osteoarthritis (OA), is associated with pain and inflammation of the joint capsule, impaired muscular stabilization, reduced range of motion and functional disability. | 22220431 |
| Inflammation, Psoriasis, Dermatitis, RANGAP1 wt Allele, Pruritus | Altered Intercellular Communication | As the inflammatory scalp conditions share similar clinical manifestations of scaling, inflammation, and pruritus, the differential diagnosis of these lesions; especially between scalp psoriasis (SP) and seborrheic dermatitis (SD) is sometimes difficult. | 22220807 |
| Inflammation, Acute Coronary Syndrome | Altered Intercellular Communication | Berberine ameliorates inflammation in patients with acute coronary syndrome following percutaneous coronary intervention. | 22220931 |
| Inflammation, Acute Coronary Syndrome, GDC AJCC Clinical Stage Terminology | Altered Intercellular Communication | Inflammation is central to the pathogenesis of acute coronary syndrome (ACS) and is associated with adverse clinical outcomes after percutaneous coronary intervention (PCI). | 22220931 |
| Multiple Organ Failure, Inflammation, Fracture | Altered Intercellular Communication | Early intramedullary nailing (IMN) of long bone fractures in severely injured patients has been evaluated as beneficial, but has also been associated with increased inflammation, multi organ failure (MOF) and morbidity. | 22221511 |
| Electrocardiogram: myocardial infarction (finding), Myocarditis | Altered Intercellular Communication | The aim of this study was to explore post-myocardial infarction (MI) myocardial inflammation. | 22222080 |
| Infarction, Inflammation | Altered Intercellular Communication | Cell depletion and isolation data confirmed that this largely reflected inflammation; CD11b(+) cells had 4-fold higher (18)FDG uptake than the infarct tissue from which they were isolated (p < 0.01). | 22222080 |
| Inflammatory abnormality of the eye, Panuveitis | Altered Intercellular Communication | Cases of ocular inflammation following penetration by urticating hairs from caterpillars and tarantulas have been previously reported and although rare, the condition is increasingly being recognised as a cause of chronic panuveitis. | 22222718 |
| vascular inflammations | Altered Intercellular Communication | Recent studies suggested an important role for regulatory T (Treg) cells in the inhibition of disease-related vascular inflammation. | 22223728 |
| vascular inflammations, Dental Plaque | Altered Intercellular Communication | Limitation of plaque progression was associated with reduced vascular inflammation and increased collagen content, indicative of plaque stabilization. | 22223728 |
| Inflammation, Atrial Fibrillation by ECG Finding, Diabetes Mellitus, Cerebrovascular accident, Endothelial dysfunction, Obesity | Altered Intercellular Communication | The increased risk of HF associated with elevated GGT persisted after adjustment for a wide range of established and novel risk factors for HF, including diabetes, stroke, obesity, systolic blood pressure, atrial fibrillation, lung function, inflammation (C-reactive protein), endothelial dysfunction (von Willebrand factor), leptin, and N terminal pro brain natriuretic peptide (adjusted hazard ratio [95% CI], 1.91 [1.07, 3.42]). | 22223732 |
| Inflammation, Joints, Synovitis | Altered Intercellular Communication | The presence of low-grade inflammation in OA joints is receiving increasing attention, with synovitis shown to be present even in the early stages of the disease. | 22225630 |
| Inflammation | Altered Intercellular Communication | How the synovial inflammation arises is unclear, but proteins in the synovial fluid of affected joints could conceivably contribute. | 22225630 |
| Inflammation | Altered Intercellular Communication | We identified 108 proteins in OA synovial fluid, including plasma proteins, serine protease inhibitors, proteins indicative of cartilage turnover, and proteins involved in inflammation and immunity. | 22225630 |
| Degenerative polyarthritis, Inflammation | Altered Intercellular Communication | Our findings suggest that plasma proteins present in OA synovial fluid, whether through exudation from plasma or production by synovial tissues, could contribute to low-grade inflammation in OA by functioning as so-called damage-associated molecular patterns in the synovial joint. | 22225630 |
| Chronic inflammation, Abnormal degeneration | Altered Intercellular Communication | The accumulation of LPC (1-acyl 16:0) and PC (diacyl 16:0/20:4) in the VV intima and media may be associated with chronic inflammation, leading to VV tissue degeneration. | 22226181 |
| Helicobacter heilmannii, Acute and chronic inflammation | Altered Intercellular Communication | Chronic active inflammation was observed in 53(56%) (p = 0.001) of the patients with H. pylori infection alone as compared to 3(37%) (p = 0.73) coinfected with H. heilmannii and H. pylori and 3(60%) coinfected with H. felis and H. pylori (p = 0.66). | 22226326 |
| Inflammation, Spondylarthritis | Altered Intercellular Communication | Anterior chest wall inflammation by whole-body magnetic resonance imaging in patients with spondyloarthritis: lack of association between clinical and imaging findings in a cross-sectional study. | 22226453 |
| Cerebrovascular Disorders, Inflammation | Altered Intercellular Communication | Systemic arterial inflammation, measured with 18FDG-PET, is common amongst subjects with both recent and prior cerebrovascular disease. | 22226631 |
| Cerebrovascular Disorders, Inflammation, Tacca leontopetaloides, Ischemic stroke | Altered Intercellular Communication | To compare systemic arterial inflammation in subjects with recent ischaemic stroke or TIA and controls with prior cerebrovascular disease. | 22226631 |
| Cerebrovascular Disorders, Inflammation, Tacca leontopetaloides, Ischemic stroke | Altered Intercellular Communication | Systemic arterial inflammation was prospectively measured by (18)F-fluorodeoxygluose positron emission tomography in 11 cases with recent ischaemic stroke or TIA, and 11 sex matched controls with prior cerebrovascular disease. | 22226631 |
| Inflammation | Altered Intercellular Communication | Arterial inflammation was common, and appeared similar, in patients with recent stroke/TIA, and controls with stroke/TIA more than two years previously. | 22226631 |
| Inflammation | Altered Intercellular Communication | Interestingly, immunoglobulin free light chains (IgLC) are able to prolong the life of neutrophils; therefore, IgLC may contribute to the chronic state of inflammation. | 22227380 |
| Inflammation, Diabetes Mellitus | Altered Intercellular Communication | Previous studies suggest that inflammation plays an important part in the pathogenesis of diabetes. | 22227739 |
| Inflammation, Coronary heart disease | Altered Intercellular Communication | Inflammation plays a pivotal role in coronary heart disease. | 22227998 |
| Inflammation, Atherosclerosis | Altered Intercellular Communication | Dendritic cells (DCs) are principal players in inflammation and atherosclerosis. | 22227998 |
| Lymphoid nodule, Inflammation, Infection caused by Helicobacter pylori | Altered Intercellular Communication | The number of CD4(+), CD25(+), and Foxp3(+) cells, and the ratio of CD25(+)/CD4(+) and Foxp3(+)/CD4(+) cells, were associated with the histological grade of the specimens, including acute inflammation, chronic inflammation, lymphoid follicle number, and Helicobacter pylori infection. | 22228968 |
| Rheumatoid Arthritis, Arthritis | Altered Intercellular Communication | Pseudoseptic arthritis is primarily described in rheumatoid arthritis and other systemic inflammatory conditions. | 22229599 |
| Inflammation, Hematoma, Hemorrhage | Altered Intercellular Communication | On physical examination, a painful mass in the hypogastrium and intense inflammation in the thigh and the proximal portion of left knee were found.Emergent multiphase contrast computed tomography revealed a large nonhomogeneous hematoma neighboring the fractured left iliopubic rami, and contrast extravasation indicated arterial bleeding. | 22229619 |
| Inflammatory Bowel Diseases, Crohn Disease, Inflammation, Ulcerative Colitis | Altered Intercellular Communication | The newly described--multigene analysis test (DiBiCol) identifying 7 inflammatory bowel disease (IBD)-specific genes in colonic mucosal biopsy differentiating between ulcerative colitis (UC) and Crohn's disease (CD) with active inflammation--is a new addition to existing methods with a higher stated sensitivity and specificity. | 22229803 |
| Gastrointestinal inflammation | Altered Intercellular Communication | We suggest that fecal calprotectin may be a marker for subclinical intestinal inflammation in AS and should be measured after stopping NSAIDs, but further endoscopic studies are needed. | 22229862 |
| Refractory anemias, Inflammation | Altered Intercellular Communication | These findings suggest that HDL is significantly altered in the setting of chronic inflammation in active RA, with resultant loss of its antiinflammatory function. | 22231638 |
| Heart failure, Myocarditis | Altered Intercellular Communication | High-Mobility-Group Box 1 (HMGB1) has been established as an important mediator of myocardial inflammation and associated with progression of heart failure (HF). | 22231645 |
| Cessation of life, Inflammation | Altered Intercellular Communication | These findings might provide a molecular basis for new strategies targeting cell death pathways in apoptosis-resistant neutrophils during systemic inflammation. | 22231730 |
| Inflammation, Atherosclerosis | Altered Intercellular Communication | Chlamydophila pneumoniae phospholipase D (CpPLD) drives Th17 inflammation in human atherosclerosis. | 22232679 |
| Dermatitis, Atopic, Psoriasis, Dermatitis | Altered Intercellular Communication | Psoriasis and atopic dermatitis are associated with quantitative and qualitative changes of peripheral NK cells, mostly shared by both diseases, supporting a common process implicating these innate effectors in skin inflammation. | 22233261 |
| ARCN1 gene, Inflammation, Airway structure, Chronic Obstructive Airway Disease, Lung diseases | Altered Intercellular Communication | Chronic obstructive pulmonary disease (COPD) is a lung disease characterized with limitation of airflow that is not completely reversible, progressive deterioration of airways and systemic inflammation. | 22233302 |
| Inflammation, Asthma, Dermatitis, Atopic | Altered Intercellular Communication | The IL-33 induces T helper 2-type inflammatory responses and is considered to play a crucial rule in allergic inflammations, such as asthma and atopic dermatitis. | 22233535 |
| Inflammation, Pancreatitis, Necrosis | Altered Intercellular Communication | Both the ARFI-VTQ and eSie touch elasticity imaging techniques may be successfully adopted in order to diagnose acute pancreatitis, to assess extent of inflammation (whether focal or diffuse), to assess peripancreatic edema, to identify presence of necrotic areas and early pseudocyst formation, to early diagnose acute recurrent attacks and to monitor patient's response to treatment. | 22233945 |
| Inflammation, Appendicitis, CTCAE | Altered Intercellular Communication | Severity of inflammation may be a risk factor for negative outcome in non-operative therapy of appendicitis. | 22234068 |
| Inflammation, Anastomosis - action, Fibrosis Assessment | Altered Intercellular Communication | Anastomotic stenosis after PG is observed in some patients after approximately 1 to 2 postoperative weeks and is attributed to acute inflammation and fibrosis around the anastomosis. | 22234082 |
| Inflammation, Atherosclerosis | Altered Intercellular Communication | Based on its multiple roles in inflammation, atherogenesis and glucose homeostasis, we hypothesised that activin A could be related to coronary atherosclerosis in T2DM. | 22234949 |
| Inflammation, Fever, CTCAE, Arthralgia, Granulomatous, Malaise, Weight decreased, Myalgia, CTCAE 5 | Altered Intercellular Communication | arthralgias, myalgia, malaise, fever, and weight loss), 3) detection of autoantibodies in patients' sera, 4) histological evidence of chronic inflammation and/or granulomatous reaction to foreign body. | 22235042 |
| Inflammation, Heart failure | Altered Intercellular Communication | Markers of inflammation, metabolic risk factors, and incident heart failure in American Indians: the Strong Heart Study. | 22235819 |
| Inflammation, Metabolic Syndrome X, Diabetes Mellitus, Heart failure, Obesity, MS gene | Altered Intercellular Communication | Inflammation may play a role in increased risk of heart failure (HF) that is associated with obesity, metabolic syndrome (MS), and diabetes. | 22235819 |
| Inflammation | Altered Intercellular Communication | This early microvascular impairment might be hypothesized as the consequence of prolonged and sustained systemic inflammation and might explain the increased cardiovascular risk conferred by Pso. | 22236480 |
| Asthma, allergic inflammation | Altered Intercellular Communication | Omalizumab may inhibit allergic inflammation and could contribute to decreasing airway remodeling in patients with asthma. | 22236804 |
| Airway structure | Altered Intercellular Communication | These findings suggest that omalizumab reduced airway wall thickness and airway inflammation. | 22236804 |
| Inflammation, Endothelial dysfunction | Altered Intercellular Communication | Elevated serum uric acid is not associated with endothelial dysfunction among healthy adults, but is inversely related to EID and EC MnSOD, and positively related to systemic inflammation. | 22237152 |
| Inflammation, Thrombosis, Endothelial dysfunction | Altered Intercellular Communication | Previous studies suggest that air pollution is related to thrombosis, inflammation, and endothelial dysfunction. | 22237295 |
| Inflammation, Atrial Fibrillation by ECG Finding | Altered Intercellular Communication | Role of inflammation in early atrial fibrillation recurrence. | 22237586 |
| Inflammation | Altered Intercellular Communication | Baseline log(2) interleukin (IL)-6 [adjusted hazard ratio (HR) 1.3, 95% confidence interval (CI) 1.0-1.7, P= 0.02] and present or previous smoking (adjusted HR 3.6, 95% CI 1.2-10.9, P= 0.03) were independently associated with early AF recurrence, suggesting that inflammation played an important role in early recurrences. | 22237586 |
| Left Ventricular Hypertrophy, Inflammation, Hypertrophy, Uremia, Hypertensive (finding) | Altered Intercellular Communication | Markers of inflammation have previously been related to left ventricular (LV) hypertrophy (LVH) in uremic and hypertensive patients. | 22237633 |
| Inflammation | Altered Intercellular Communication | Further studies are motivated to investigate a pathogenetic role of inflammation for abnormal LV geometry and function. | 22237633 |
| vascular inflammations | Altered Intercellular Communication | Immunostaining against T-cells (CD3) and monocytes and macrophages (CD68) was used to explore a putative association between TGF-b and BMP signaling and vascular inflammation. | 22237716 |
| Vasculitis, Dental Plaque | Altered Intercellular Communication | No significant relationships were found between Smad phosphorylation and vessel wall inflammation or plaque vulnerability. | 22237716 |
| Proteinuria, Tubular atrophy, Interstitial inflammation | Altered Intercellular Communication | Increased epithelial syndecan-1 in allografts correlated with low proteinuria and serum creatinine, less interstitial inflammation, less tubular atrophy, and prolonged allograft survival. | 22237752 |
| Myelitis, Unspecified visual loss | Altered Intercellular Communication | The case of the Marquis de Causan (1804): an early account of visual loss associated with spinal cord inflammation. | 22237820 |
| Myelitis, Unspecified visual loss | Altered Intercellular Communication | Portal's report, which fascinated some of the most renowned 19th century pioneers in the field of neurology but fell into oblivion later, represents the first account of visual loss in a patient with spinal cord inflammation but no brain pathology in the Western literature known so far--published more than 60 years prior to Thomas Clifford Allbutt's much cited note on a patient with myelitis and a "sympathetic eye disorder". | 22237820 |
| Inflammation, Dental Plaque, atherosclerotic | Altered Intercellular Communication | Inflammation within atherosclerotic plaques is associated with instability of the plaque and future cardiovascular events. | 22239891 |
| Inflammation, Failure (biologic function), Atherosclerosis | Altered Intercellular Communication | Differences in lesion extraction technique, lesion size, the degree of inflammation, and imaging coregistration techniques may have been responsible for the failure to observe the strong correlations with vascular FDG uptake observed in previous studies of the carotid artery and in several animal models of atherosclerosis. | 22239891 |
| Inflammation, Hypersensitivity, Atherosclerosis | Altered Intercellular Communication | Other important morphological features such as fibrin accumulation, excessive inflammation (hypersensitivity), and in-stent atherosclerosis were characterized by OFDI; however, the similarly dark appearance of these tissues did not allow for direct visual discrimination. | 22239896 |
| Tumor necrosis, Inflammation, Adenocarcinoma Of Esophagus, Neoplasms | Altered Intercellular Communication | The relationship between tumour necrosis, tumour proliferation, local and systemic inflammation, microvessel density and survival in patients undergoing potentially curative resection of oesophageal adenocarcinoma. | 22240784 |
| Dysautonomia | Altered Intercellular Communication | Depending on the disease burden, MG patients may experience chronic dysregulation of both the hormonal stress axis and the immune system, consequently, aggravating the disease itself but also leading to secondary psychopathological abnormalities. | 22240858 |
| Inflammation, Liver Failure | Altered Intercellular Communication | Neither signs of hepatic or renal failure nor of inflammation or impaired acid-base balance allowed a prediction of survival in these patients. | 22241001 |
| Carotid Atherosclerosis, Inflammation, Hypotension, Orthostatic | Altered Intercellular Communication | In older nondiabetic adults only orthostatic hypotension seems to independently correlate with increased carotid atherosclerosis and systemic inflammation. | 22241141 |
| Inflammatory Bowel Diseases, Inflammation | Altered Intercellular Communication | Intestinal epithelial barrier disruption is a feature of inflammatory bowel disease (IBD), but whether barrier disruption precedes or merely accompanies inflammation remains controversial. | 22241861 |
| Inflammation, Ulcerative Colitis, Colitis | Altered Intercellular Communication | Our results revealed that lipid rafts were disrupted in IFN-g-treated cells, in the ilea of mice with subclinical colitis, and in UC patients with quiescent inflammation. | 22241861 |
| Inflammation, Rheumatic Fever | Altered Intercellular Communication | Rabbits received intra-articular injections of lipopolysaccharides (LPS) to induce inflammation that mimic rheumatic arthritis. | 22242954 |
| Inflammation | Altered Intercellular Communication | We examined and compared the bioceramic and control groups to see if bioceramic was capable of relieving inflammation in the joints by subtracting the final and initial uptake amount of FDG (max SUV). | 22242954 |
| Inflammation, S100A4 protein, human | Altered Intercellular Communication | Chronic inflammation, like in BE, markedly increase the risk of malignant transformation. | 22243485 |
| Inflammatory Bowel Diseases, Inflammation | Altered Intercellular Communication | Modulation of intestinal microbiota by non-digestible carbohydrates may reduce inflammation in inflammatory bowel disease (IBD). | 22243836 |
| Acute and chronic inflammation, Colitis | Altered Intercellular Communication | Colitis was significantly reduced in all FOS-fed rats compared to the control diet, whereas inulin decreased chronic intestinal inflammation in only half the number of animals. | 22243836 |
| Acute and chronic inflammation, Clostridium difficile colitis, Family Peptostreptococcaceae | Altered Intercellular Communication | In conclusion, FOS increased the abundance of Bifidobacterium spp., whereas both fructans reduced Clostridium cluster XI and C. difficile toxin gene expression, correlating with a reduction of chronic intestinal inflammation. | 22243836 |
| Inflammation, Hyperplastic Polyp, Observation Method - Coagulation | Altered Intercellular Communication | Microparticles (MP) are small membrane vesicles, released from activated, damaged and apoptotic endothelial cells (EMP) or platelets (PMP) that may actively modulate inflammation, coagulation and vascular function. | 22245039 |
| Malignant neoplasm of testis, Inflammation | Altered Intercellular Communication | It is important to distinguish this activity from other possible malignant and benign conditions such as lymph node activity, testicular cancer, metastatic disease activity, inflammation and urine skin contamination artefact. | 22245311 |
| Inflammation, Cardiovascular Diseases, Diabetes Mellitus, Obesity, Disease | Altered Intercellular Communication | APOE4) or involved in pathologic processes contributing to the disorder, including inflammation, diabetes, obesity and cardiovascular disease. | 22245343 |
| Refractory anemias, Inflammation | Altered Intercellular Communication | In RA, our results show a greater relative abundance of proteins related to complement activation, inflammation and the immune response, such as the major matrix metalloproteinases and several neutrophil-related proteins. | 22245418 |
| Gastroesophageal reflux disease, Primary malignant neoplasm, Adenocarcinoma Of Esophagus | Altered Intercellular Communication | Gastroesophageal reflux disease is a strong risk factor for esophageal adenocarcinoma, but it is not clear whether the mucosal inflammation that develops in patients with reflux disease promotes this cancer. | 22245963 |
| Inflammation, Adenocarcinoma Of Esophagus | Altered Intercellular Communication | Inflammation therefore might be an important factor in the progression from reflux to esophageal adenocarcinoma. | 22245963 |
| Fibrosis Assessment, Pneumonitis | Altered Intercellular Communication | Treatment with intraperitoneal recombinant human (rh) ACE2 (2 mg/kg) for 21 days improved survival, exercise capacity, and lung function and decreased lung inflammation and fibrosis in male BLM-WT mice. | 22246130 |
| Inflammation, Carcinoma of lung | Altered Intercellular Communication | Adipokines and systemic inflammation in weight-losing lung cancer patients. | 22246553 |
| Inflammation, Non-Small Cell Lung Carcinoma, Advanced Lung Non-Small Cell Squamous Carcinoma | Altered Intercellular Communication | The objective of the present study was to investigate the relationship of adipokines and systemic inflammation in weight-losing advanced-stage non-small-cell lung cancer (NSCLC) patients. | 22246553 |
| Inflammation | Altered Intercellular Communication | However, there was no correlation between adipokines and markers of systemic inflammation. | 22246553 |
| Inflammation, Cachexia | Altered Intercellular Communication | These results revealed a lack of association between adipokine levels and systemic inflammation with cancer cachexia. | 22246553 |
| Apolipoproteins B, vascular inflammations | Altered Intercellular Communication | Apolipoprotein B (ApoB) directly reflects the number of plasma atherogenic lipoproteins, and may play a major role in vascular inflammation. | 22246850 |
| Inflammation, Fibrosis Assessment, Idiopathic Pulmonary Fibrosis | Altered Intercellular Communication | However, analyses of mice receiving bleomycin (BLM) as a model of IPF established the importance of preceding inflammation for the formation of fibrosis. | 22246863 |
| Malignant Lesion | Altered Intercellular Communication | Benign lesions comprised 102 (85.7%) cases, malignant lesions comprised 14 (11.8%) cases and inflammation/abscess was found in 3 (2.5%) cases. | 22246926 |
| Inflammation, Cervical Intraepithelial Neoplasia | Altered Intercellular Communication | The CA of histology- and OCT-based judgments suggests that the diagnostic process may be characterized in terms of two stochastically independent underlying ("latent") variables, the first of them reflecting the definiteness with which CIN classes are identified, the second reflecting a bias towards diagnosing inflammation on the side of the OCT-based judgments. | 22246983 |
| Inflammation | Altered Intercellular Communication | This finding is supported by the results of LDAs, where histology and OCT categorizations differ in particular with respect to the positions of inflammation and CIN1. | 22246983 |
| Inflammation, Meningitis | Altered Intercellular Communication | Symptoms of cerebral involvement or signs of systemic inflammation were rare in children with LM compared to children non-Lyme aseptic meningitis. | 22247243 |
| Inflammation, destruction joint, Rheumatoid Arthritis | Altered Intercellular Communication | IgG glycosylation changes and MBL2 polymorphisms: associations with markers of systemic inflammation and joint destruction in rheumatoid arthritis. | 22247351 |
| Refractory anemias, Inflammation, destruction joint, Rheumatoid Arthritis | Altered Intercellular Communication | To examine whether IgG glycosylation changes and MBL2 genotypes are associated with systemic inflammation and joint destruction in rheumatoid arthritis (RA). | 22247351 |
| Inflammation, Tumor necrosis | Altered Intercellular Communication | Systemic inflammation was assessed by serum levels of C-reactive protein (CRP), interleukin 6 (IL-6), and tumor necrosis factor-a (TNF-a). | 22247351 |
| Refractory anemias | Altered Intercellular Communication | Our results suggest that inflammation-associated decreased galactosylation of IgG combined with high expression MBL2 genotypes are involved in the pathophysiology of RA. | 22247351 |
| Interstitial inflammation | Altered Intercellular Communication | Interstitial inflammation was less severe in patients with PTU-induced AAV (p < 0.05). | 22247359 |
| nervous system disorder, "Alzheimers Disease", Data types - Address | Altered Intercellular Communication | Alzheimer's disease (AD) brain shows an ongoing inflammatory condition and non-steroidal anti-inflammatories diminish the risk of suffering the neurologic disease. | 22248049 |
| Inflammation, Dyslipidemias | Altered Intercellular Communication | Hemodialysis patients had increased protein OS and associations of inflammation and dyslipidemia were also observed in these dialysis groups. | 22248198 |
| Calcified (qualifier), Inflammation | Altered Intercellular Communication | Klotho null mice are a model for premature aging and exhibit calcific nodules in the aortic valve hinge-region, but do not exhibit leaflet thickening, ECM disorganization, or inflammation. | 22248532 |
| Inflammation, FAM126A gene, TNM Staging System, Hypertension, CTCAE, Liver Cirrhosis | Altered Intercellular Communication | Decreased liver size and indirect evidence of more severe portal hypertension and earlier TNM stage compared with HBV monoinfection indicate that HDV infection causes HCC in a different way, possibly indirectly by inducing inflammation and cirrhosis. | 22249087 |
| Colitis, Ulcer | Altered Intercellular Communication | Ileocolonoscopy revealed colonic inflammation with ulcers and pseudopolyps. | 22249306 |
| Inflammation, Illness (finding), Traumatic injury | Altered Intercellular Communication | Heart rate variability (HRV) is a sensitive marker of altered sympathetic-parasympathetic function and is reduced in inflammation, illness, and trauma. | 22249435 |
| Inflammation, Sleep Apnea, Obstructive | Altered Intercellular Communication | Obstructive sleep apnea has been associated with generalized inflammation and nervous-endocrine, cardiovascular, and other systemic biophysiologic phenomena. | 22249630 |
| Airway structure | Altered Intercellular Communication | Low serum 25-hydroxyvitamin D (25-[OH]D) levels have been associated with lower FEV(1), impaired immunologic control, and increased airway inflammation. | 22250141 |
| Inflammation, Primary malignant neoplasm, FAM126A gene | Altered Intercellular Communication | HCC may be an unusual cancer affected by continuous inflammation that can lead to consistent upregulation of transforming growth factor-beta (TGF-beta). | 22251470 |
| Inflammation, Chronic cholecystitis, Nesidioblastosis | Altered Intercellular Communication | Endocrine cell hyperplasia may be related to longstanding inflammation as in chronic cholecystitis and all secreted hormones from the described ECs can support pathologic process in the choledochus, i.e. | 22251519 |
| Muscle Contraction, Inflammation, Fibrosis Assessment | Altered Intercellular Communication | inflammation, increased mucus secretion, fibrosis, muscle contraction, etc. | 22251519 |
| Inflammation, Chronic cholecystitis, Nesidioblastosis | Altered Intercellular Communication | Endocrine cell hyperplasia may be related to longstanding inflammation as in chronic cholecystitis and all secreted hormones from the described ECs can support pathologic process in the choledochus, i.e. | 22251519 |
| Inflammation, Gallbladder Carcinoma | Altered Intercellular Communication | Chronic inflammation is a risk factor for gallbladder carcinoma. | 22251522 |
| Inflammation, Gallbladder Carcinoma | Altered Intercellular Communication | The molecular mechanisms linking inflammation and gallbladder carcinogenesis are incompletely understood. | 22251522 |
| Contracture of bladder neck, Urethral Stenosis, Prostate, prostatitis | Altered Intercellular Communication | Impact of asymptomatic prostatitis on re-operations due to urethral stricture or bladder neck contracture developed after TUR-P. To evaluate the relationship between pathologically proven prostatic inflammation (PI) and re-operation rates due to urethral stricture (US) or bladder neck contracture (BNC) after transurethral resection of prostate (TUR-P). | 22252218 |
| prostatitis | Altered Intercellular Communication | In logistic regression analysis, duration of initial TUR-P and PI were found to be independent risk factors for development of BNC or US after TUR-P. Prostatic inflammation on TUR-P pathology is an independent variable affecting the development of US or BNC. | 22252218 |
| Inflammation, Nasal Polyps, Chronic sinusitis | Altered Intercellular Communication | Over half of chronic rhinosinusitis with nasal polyps (CRSwNP) patients in China show noneosinophilic inflammation. | 22252861 |
| Aneurysmal, Inflammation | Altered Intercellular Communication | We hypothesize that inflammation of the gland had weakened the wall of the adjacent facial vein, causing aneurysmal dilatation. | 22253006 |
| Inflammatory abnormality of the eye, Blepharoconjunctivitis | Altered Intercellular Communication | To compare the efficacy and safety of loteprednol etabonate 0.5%/tobramycin 0.3% (LE/T) and dexamethasone 0.1%/tobramycin 0.3% (DM/T) ophthalmic suspensions in a Chinese population with ocular inflammation associated with blepharokeratoconjunctivitis (BKC). | 22256909 |
| Chronic suppurative inflammation, Actinomycosis | Altered Intercellular Communication | After nephrectomy, sulfur granules with chronic suppurative inflammation were seen microscopically, and the histopathological diagnosis was renal actinomycosis. | 22257547 |
| Traumatic injury | Altered Intercellular Communication | In 1997, 43% of the total elbow arthroplasties were associated with trauma and 48%, with inflammatory conditions. | 22257996 |
| Communicable Diseases, Inflammation | Altered Intercellular Communication | Inflammation and infection are associated with premature birth and with activation of the fetal immune system. | 22258123 |
| Inflammation, Fibrosis Assessment | Altered Intercellular Communication | Cases of IA tend to have more histologically active inflammation except for a relatively normal erythrocyte sedimentation rate, localised lesions and milder intimal fibrosis than cases of TA. | 22259176 |
| ARCN1 gene, Inflammation, Chronic Obstructive Airway Disease, Deficient Food Intake | Altered Intercellular Communication | Whereas nutrition deficits are recognized as an expression of systemic inflammation in the elderly with diagnosed chronic obstructive pulmonary disease (COPD), if they occur in symptomatic elderly smokers, unfulfilled COPD criteria are not confirmed. | 22259244 |
| Inflammation, Cardiac complication, Depression, CTCAE, Chronic Kidney Diseases | Altered Intercellular Communication | Serum T3 depression predicts a negative outcome in chronic kidney disease (CKD) patients and may be associated with cardiovascular complications or chronic inflammation. | 22260378 |
| Inflammation | Altered Intercellular Communication | High C3 may be considered a hallmark of inflammation and C3 revealed the highest predictive value for response to anti-TNF. | 22260811 |
| Inflammation, Periodontal Route of Administration | Altered Intercellular Communication | Participants had widespread periodontal inflammation but limited periodontal destruction. | 22261235 |
| Inflammation, Periodontal Route of Administration | Altered Intercellular Communication | GCF cytokine levels were not strongly associated with serum cytokine levels in pregnant women with widespread periodontal inflammation but limited periodontal destruction. | 22261235 |
| Inflammation, Ulcerative Colitis, Mucosal ulcer, Chronic inflammatory disorder | Altered Intercellular Communication | Ulcerative colitis (UC) is a chronic inflammatory disease characterized by recurrent inflammation and ulcerations of colonic mucosa and an inappropriate and delayed healing. | 22261534 |
| Inflammation, Ulcerative Colitis | Altered Intercellular Communication | Correlation analysis was also performed between ADA and other inflammation markers of UC. | 22261534 |
| Ulcerative Colitis | Altered Intercellular Communication | Although ADA has been shown to increase in several inflammatory conditions, there are no literature data indicating an alteration in UC. | 22261534 |
| Inflammation, Cerebrovascular accident | Altered Intercellular Communication | Local inflammation in the brain following stroke is thought to enhance damage. | 22261543 |
| Inflammation, Diabetes Mellitus | Altered Intercellular Communication | Chronic inflammation and decreased frequency of regulatory T cells (Tregs) in visceral adipose tissue contribute to the propagation of insulin resistance to diabetes mellitus. | 22262764 |
| Inflammation, Adherence (attribute) | Altered Intercellular Communication | Because platelet adherence to leukocytes allows for both firm adhesion to endothelial cells and augmented transcellular conversion of leukotrienes, a disturbance in platelet-leukocyte interactions may be partly responsible for the respiratory tissue inflammation and the overproduction of cysLTs that characterize AERD. | 22262771 |
| Refractory anemias, Inflammation | Altered Intercellular Communication | COMP-C3b levels in RA decrease during TNF-a inhibition differently from those of CRP, suggesting that formation of COMP-C3b relates to disease features not reflected by general inflammation measures. | 22264230 |
| Pulmonary Emphysema | Altered Intercellular Communication | Targeted deletion of Jun/AP-1 in alveolar epithelial cells causes progressive emphysema and worsens cigarette smoke-induced lung inflammation. | 22265050 |
| Chronic Obstructive Airway Disease, Pulmonary Emphysema, Pneumonitis | Altered Intercellular Communication | In this study, we report decreased expression levels of c-Jun mRNA and protein in the lung tissues of patients with advanced chronic obstructive pulmonary disease, and the genetic deletion of c-Jun specifically in alveolar epithelial cells causes progressive emphysema with lung inflammation and alveolar air space enlargement, which are cardinal features of emphysema. | 22265050 |
| Pulmonary Emphysema, Pneumonitis | Altered Intercellular Communication | These results demonstrate that the c-Jun/activator protein 1 pathway is critical for maintaining lung alveolar cell homeostasis and that loss of its expression can contribute to lung inflammation and progressive emphysema. | 22265050 |
| Inflammation, Necrosis | Altered Intercellular Communication | The severe peripheral flap inflammation resulted in stromal necrosis that was unresponsive to intensive topical steroid but improved rapidly on oral prednisone. | 22265184 |
| Inflammation | Altered Intercellular Communication | Two important protective factors for low-grade inflammation may be physical activity (PA) and fitness. | 22265274 |
| Inflammation | Altered Intercellular Communication | High PA in adolescence may play an indirect role on lessening low-grade inflammation through improvements in fitness. | 22265274 |
| Inflammation, Coronary Arteriosclerosis | Altered Intercellular Communication | There is evidence that chronic inflammation may promote atherosclerotic disease. | 22265583 |
| Asthma | Altered Intercellular Communication | Impact of add-on pranlukast in stable asthma; the additive effect on peripheral airway inflammation. | 22265857 |
| Airway structure, Asthma | Altered Intercellular Communication | The importance of airway inflammation has been highlighted in the pathophysiology of asthma. | 22265857 |
| Airway structure | Altered Intercellular Communication | Even in controlled asthmatics treated with inhaled corticosteroid (ICS), residual airway inflammation is reported. | 22265857 |
| Airway structure, Asthma | Altered Intercellular Communication | The addition of oral pranlukast to ICS or ICS + LABA therapy may improve asthma control with reducing distal airway inflammation. | 22265857 |
| Kidney Failure, Chronic, Chronic inflammation, Complications of Diabetes Mellitus, Diabetes Mellitus, Non-Insulin-Dependent | Altered Intercellular Communication | Levels of proinflammatory cytokines associate with risk for developing type 2 diabetes but whether chronic inflammation contributes to the development of diabetic complications, such as ESRD, is unknown. | 22266663 |
| Inflammation, Musculoskeletal Pain, Aortic Stiffness | Altered Intercellular Communication | Polymyalgia rheumatica is associated with increased aortic stiffness which may improve upon reduction of systemic inflammation induced by treatment with glucocorticoids. | 22267333 |
| Inflammation, Atherosclerosis | Altered Intercellular Communication | It is not clear, however, whether periodontal inflammation may be associated with increased markers of atherosclerosis in these patients. | 22267416 |
| Arterial Stiffness, Inflammation, square decimeter | Altered Intercellular Communication | Periodontal inflammation in patients with DM2 seems to be associated with increased IMT and BP, but not with greater arterial stiffness. | 22267416 |
| Immunologic Deficiency Syndromes, Inflammation | Altered Intercellular Communication | In ART-naive patients, severe immune deficiency but not inflammation could be an early risk factor for altered insulin sensitivity. | 22267473 |
| Inflammation, Candidiasis | Altered Intercellular Communication | Oral candidiasis is often accompanied by severe inflammation, resulting in a decline in the quality of life of immunosuppressed individuals and elderly people. | 22267663 |
| Inflammation | Altered Intercellular Communication | Enhanced inflammation could contribute to persistent obstruction by impairing pulmonary vascular cell function in CTEPH. | 22267767 |
| Asthma | Altered Intercellular Communication | ASMC syndecan-4 production during Th1 inflammatory conditions may regulate chemokine activity and mast cell recruitment to the ASM in asthma. | 22268118 |
| Pulmonary Emphysema, Pneumonitis | Altered Intercellular Communication | Deregulated Stat3 signaling dissociates pulmonary inflammation from emphysema in gp130 mutant mice. | 22268122 |
| Hyperactive behavior, Pulmonary Emphysema, Pneumonitis | Altered Intercellular Communication | Genetic reduction of Stat3 hyperactivity in gp130(F/F):Stat3(-/+) mice prevented lung inflammation and excessive protease activity; however, emphysema still developed. | 22268122 |
| ARCN1 gene, Pneumonitis | Altered Intercellular Communication | In support of these findings, Stat3 activation levels in human lung tissue correlated with the extent of pulmonary inflammation but not airflow obstruction in COPD. | 22268122 |
| Pulmonary Emphysema, Pneumonitis | Altered Intercellular Communication | Collectively, our data suggest that IL-6 promotes emphysema via upregulation of Stat3-independent apoptosis, whereas IL-6 induction of lung inflammation occurs via Stat3. | 22268122 |
| ARCN1 gene, Pulmonary Emphysema, Pneumonitis | Altered Intercellular Communication | We propose that while discrete targeting of Stat3 may alleviate pulmonary inflammation, global targeting of IL-6 potentially represents a therapeutically advantageous approach to combat COPD phenotypes where emphysema predominates. | 22268122 |
| Epithelial Damage, Inflammation | Altered Intercellular Communication | CC is characterized histopathologically by an increase in the thickness of the subepithelial collagen layer to at least 10 mm, epithelial damage, and chronic inflammation of the lamina propria. | 22269295 |
| Amyotrophic Lateral Sclerosis, Inflammation, MS gene, Nerve Degeneration | Altered Intercellular Communication | Concurrent multiple sclerosis and amyotrophic lateral sclerosis: where inflammation and neurodegeneration meet? | 22269588 |
| Airway structure, Asthma, Arthritis, Infectious | Altered Intercellular Communication | Blood NKT cells decreased during infection-associated asthma exacerbation and were inversely associated with eosinophilic airway inflammation, suggesting that blood NKT cells might be mobilized to the airways and lungs during asthma exacerbation in humans. | 22269676 |
| Parkinson Disease, "Alzheimers Disease", palladium, Data types - Address | Altered Intercellular Communication | Monoamine oxidase-B (Mao-B) catalysing the breakdown of the neurotransmitter dopamine, is known to be involved in the pathophysiology of Parkinson's (PD) and Alzheimer's disease (AD). | 22270014 |
| Dissection of carotid artery, Labor (Childbirth), Traumatic injury | Altered Intercellular Communication | Intimal injury related to the Valsalva maneuver during labor as well as hemodynamic and hormonal changes related to pregnancy are presumed causes of peripartum spontaneous carotid artery dissection. | 22270449 |
| Hematoma, Subdural, Inflammation | Altered Intercellular Communication | We hypothesise that dural mast cells may contribute to neurogenic inflammation and the clinical features of subdural haemorrhage. | 22270653 |
| Inflammation | Altered Intercellular Communication | Although periportal and lobular necroinflammation vanished, portal inflammation persisted in 66%. | 22271347 |
| Inflammation | Altered Intercellular Communication | Despite ductular proliferation vanishing and lobular zonation restoration, portal inflammation and sinusoidal capillarization may not regress after viral eradication. | 22271347 |
| Inflammation, Fibrosis Assessment, Injury of liver | Altered Intercellular Communication | The deficiency of HIFs in macrophages did not affect liver injury or inflammation after BDL but reduced PDGF-B mRNA and protein, suggesting that HIF activation in macrophages may promote fibrosis by regulating the production of PDGF-B. | 22271822 |
| Granulomatosis with polyangiitis, Orbital Pseudotumor | Altered Intercellular Communication | Treatment of orbital inflammation with rituximab in Wegener's granulomatosis. | 22272561 |
| Orbital Pseudotumor | Altered Intercellular Communication | Ten WG patients with orbital inflammation were included in this case-series. | 22272561 |
| Orbital Pseudotumor | Altered Intercellular Communication | All patients had orbital inflammation demonstrated by CT-scan before treatment (3 had bilateral and 7 unilateral orbital involvement). | 22272561 |
| Alzheimers Disease", Data types - Address | Altered Intercellular Communication | In Alzheimer's disease (AD) brain, the levels of these neurosteroids are known to be altered compared to age-matched non-demented controls. | 22272612 |
| Inflammation, "Alzheimers Disease | Altered Intercellular Communication | Pharmacological inhibition of PKR in APPswePS1dE9 mice transiently prevents inflammation at 12 months of age but increases Ab42 levels in the late stages of the Alzheimer's disease. | 22272616 |
| Inflammation, Data types - Address | Altered Intercellular Communication | Whether or not inflammation represents a possible cause of AD or occurs as a consequence of the disease process, or, alternatively, whether the inflammatory response might be beneficial to slow the disease progression remains to be elucidated. | 22272623 |
| Inflammation, Data types - Address | Altered Intercellular Communication | An important piece of evidence supporting a pathophysiologic role for inflammation in AD is the number of inflammatory mediators that have been found to be differentially regulated in AD patients, and specific ones may provide utility as part of a biomarker panel to not only aid early AD diagnosis, but follow its progression. | 22272623 |
| Inflammation, Carcinogenesis | Altered Intercellular Communication | One of COX-2 main metabolites is prostaglandin E2 (PGE2), which is involved both in inflammation and carcinogenesis. | 22272632 |
| Low Back Pain, Inflammation, LAURIN-SANDROW SYNDROME, Neurogenic claudication | Altered Intercellular Communication | Reports on LSS treatment with ESIs have not differentiated between neurogenic claudication, which is believed to result from nerve root compression, and lumbar radicular pain, thought to be caused by inflammation. | 22272730 |
| Inflammation | Altered Intercellular Communication | CT-guided biopsy revealed chronic inflammation of those pulmonary nodules, and laboratory studies disclosed elevated serum levels of carbohydrate antigen 19-9 (CA 19-9) and CA 125. | 22273501 |
| Inflammation, Erosion lesion, Rheumatoid Arthritis | Altered Intercellular Communication | Inter- and intra-observer agreement of high-resolution ultrasonography and power Doppler in assessment of joint inflammation and bone erosions in patients with rheumatoid arthritis. | 22274131 |
| Inflammation, Erosion of bone | Altered Intercellular Communication | Five members of the "Escuela de Ecografia del Colegio Mexicano de Reumatologia" tested their inter- and intra-observer reliabilities in the assessment of basic sonographic findings of joint inflammation and bone erosion. | 22274131 |
| Inflammation, Hyperplasia, Spondylitis | Altered Intercellular Communication | Evidence indicates that the hyperplasia and inflammation of synovial tissues are significantly related to the pathogenic process of ankylosing spondylitis (AS). | 22274560 |
| Irritation - emotion, Inflammation | Altered Intercellular Communication | Gingival irritation and inflammation due to poor oral hygiene were the major precipitating factors. | 22274762 |
| Inflammation, Arthritis | Altered Intercellular Communication | Link between traditional cardiovascular risk factors and inflammation in patients with early arthritis: results from a French multicenter cohort. | 22275176 |
| Inflammation, Arthritis, Each (qualifier value) | Altered Intercellular Communication | To compare the characteristics of traditional cardiovascular risk factors for untreated patients with early arthritis (EA) and healthy subjects, and to look for a link between cardiovascular risk factors and inflammation in EA patients. | 22275176 |
| Inflammation, Chronic disease | Altered Intercellular Communication | Controlled inflammation has become a central focus in chronic disease therapeutics. | 22276585 |
| Inflammation | Altered Intercellular Communication | Exaggerated inflammation is a common factor that contributes to matrix destruction, cellular senescence, and nonhealing in a variety of disease processes. | 22276585 |
| Inflammation | Altered Intercellular Communication | Efforts at controlling inflammation have traditionally concentrated on systemic antagonists to inflammation such as nonsteroidal anti-inflammatory agents. | 22276585 |
| Inflammation, Necrosis | Altered Intercellular Communication | Statistical correlation was evaluated for tumour histotype, mitotic count (MC), nuclear grade (NG), necrosis, lymphoid response (grade of inflammation) and desmoplasia with regard to survival. | 22276610 |
| Inflammation, Hypersensitivity, Diverticular Diseases | Altered Intercellular Communication | Visceral hypersensitivity in symptomatic diverticular disease and the role of neuropeptides and low grade inflammation. | 22276853 |
| Inflammation, Hypersensitivity, Diverticular Diseases | Altered Intercellular Communication | Patients with symptomatic diverticular disease exhibit visceral hypersensitivity, and this may be mediated by ongoing low grade inflammation and upregulation of tachykinins. | 22276853 |
| Inflammation, Terminal Osseous Dysplasia and Pigmentary Defects, Hypertension, CTCAE | Altered Intercellular Communication | Inflammation is a pathogenic factor for target-organ damage (TOD) in hypertension. | 22277919 |
| Inflammation | Altered Intercellular Communication | Inflammatory parameters are significantly and independently associated with UAE in prehypertensive subjects, suggesting that inflammation may be a pathogenic factor for the early vascular or TOD in these individuals. | 22277919 |
| Adrenocorticotropic hormone (ACTH) deficiency (disorder), Hashimoto Disease, Thyroid Crisis, Craniocerebral Trauma | Altered Intercellular Communication | Isolated adrenocorticotropic hormone deficiency associated with Hashimoto's disease and thyroid crisis triggered by head trauma. | 22278027 |
| Inflammation, Systemic disease, Disability, Damage, Arthritis, Psoriatic | Altered Intercellular Communication | Psoriatic arthritis is a chronic systemic disease in which patients develop persistent inflammation of the skin and joints, leading to disability and joint damage. | 22278305 |
| Inflammation, Neoplasms | Altered Intercellular Communication | The extracellular component hyaluronan (HA) plays an important role in regulatory processes such as inflammation, wound healing and tumour progression. | 22278305 |
| Inflammation | Altered Intercellular Communication | At any site of inflammation HA can be depolymerized to low-molecular weight fragments, which, in turn, induce an array of inflammatory mediators that can lead to chronic inflammation. | 22278305 |
| Inflammation, Hypertension, CTCAE, Endothelial dysfunction | Altered Intercellular Communication | In this Mongolian population, IR and elevated biomarkers of inflammation and endothelial dysfunction were related to hypertension and the coexistence of IR and elevated biomarkers of inflammation and endothelial dysfunction increased the risk of hypertension. | 22278626 |
| Sepsis, Inflammation, Communicable Diseases | Altered Intercellular Communication | Use of a weighted, automated analysis of the differential blood count to differentiate sepsis from non-infectious systemic inflammation: the intensive care infection score (ICIS). | 22280231 |
| Inflammation, Vitreous opacities | Altered Intercellular Communication | Immunocytochemical diagnosis as inflammation by vitrectomy cell blocks in patients with vitreous opacity. | 22281090 |
| Inflammation, Vitreous opacities | Altered Intercellular Communication | To describe the clinical and cytopathologic characteristics in patients with vitreous opacity of unknown cause or preceding inflammation, diagnosed cytopathologically as inflammation. | 22281090 |
| Inflammation, Vitreous opacities | Altered Intercellular Communication | Forty-three consecutive patients (61 eyes) who underwent vitrectomy for vitreous opacity of unknown cause or preceding inflammation and were diagnosed cytopathologically with inflammation at one institution in 6 years from 2005 to 2010. | 22281090 |
| Inflammation, Primary cerebral lymphoma, Vitreous opacities, Lymphoma | Altered Intercellular Communication | Inflammation was diagnosed in 2 patients with vitreous opacity who had a preceding onset of brain lymphoma or systemic lymphoma. | 22281090 |
| Inflammation, Vitreous opacities | Altered Intercellular Communication | The presence of macrophages, combined with small T lymphocytes, was a major sign in intravitreal inflammation, manifesting as vitreous opacity. | 22281090 |
| Inflammation, Endothelial dysfunction, Atherosclerosis | Altered Intercellular Communication | Inflammation plays an important role in the pathophysiology of atherosclerosis and endothelial dysfunction, and occurs after percutaneous coronary intervention (PCI). | 22281412 |
| Mortality, Premature, Inflammation, Metabolic Syndrome X | Altered Intercellular Communication | Hyperadiponectinemia protects against premature death in metabolic syndrome model mice by inhibiting AKT signaling and chronic inflammation. | 22281526 |
| Inflammation, Impaired | Altered Intercellular Communication | We hypothesized that CAT scores at exacerbation relate to exacerbation severity as measured by exacerbation duration, lung function impairment, and systemic inflammation. | 22281834 |
| Inflammation, Endophthalmitis, CTCAE | Altered Intercellular Communication | There were three cases (0.3%) of endophthalmitis (inflammation of the internal coats of the eye). | 22282278 |
| Inflammation, Pulmonary Emphysema | Altered Intercellular Communication | In animal emphysema models, palovarotene reduced inflammation, promoted structural repair and functional improvement. | 22282548 |
| Uremia, Inflammation | Altered Intercellular Communication | These data suggest a potential link between the high levels of inflammation and cardiovascular mortality in uremia. | 22282592 |
| Malignant tumor of colon, Colorectal Carcinoma, Gastrointestinal inflammation | Altered Intercellular Communication | Because chronic intestinal inflammation is a risk factor for colorectal cancer, we hypothesized that genetic variants of inflammatory mediators, such as mannose-binding lectin 2 (MBL2), are associated with colon cancer susceptibility. | 22282660 |
| Refractory anemias, Inflammation, Rheumatoid Arthritis, Knee joint | Altered Intercellular Communication | To determine whether dynamic contrast-enhanced magnetic resonance imaging (DCE-MRI) evaluated using semi-automatic image processing software can accurately assess synovial inflammation in rheumatoid arthritis (RA) knee joints. | 22283139 |
| Refractory anemias, Inflammation | Altered Intercellular Communication | In 17 RA patients undergoing knee surgery, the average grade of histological synovial inflammation was determined from four biopsies obtained during surgery. | 22283139 |
| Inflammation | Altered Intercellular Communication | The IRE from the Quick ROI and the Precise ROI revealed high correlations to the grade of histological inflammation (Spearman's correlation coefficient (rho) = 0.70, p = 0.001 and rho = 0.74, p = 0.001, respectively). | 22283139 |
| Refractory anemias, Inflammation | Altered Intercellular Communication | DCE-MRI provides fast and accurate assessment of synovial inflammation in RA patients. | 22283139 |
| Sleep-Disordered Breathing, Inflammation, Metabolic Syndrome X | Altered Intercellular Communication | An investigation into the relationship between sleep-disordered breathing, the metabolic syndrome, cardiovascular risk profiles, and inflammation between South Asians and Caucasians residing in the United Kingdom. | 22283669 |
| Sleep-Disordered Breathing, Inflammation | Altered Intercellular Communication | There was no independent association between SDB and markers of inflammation. | 22283669 |
| Pancreatic Neoplasm, Pancreatitis | Altered Intercellular Communication | K-ras mutations were extremely rare in pancreatic inflammation and other pancreatic tumors. | 22284089 |
| Autoimmune Diseases, Inflammation, Rheumatoid Factor | Altered Intercellular Communication | Protein citrullination is present in the rheumatoid synovium, presumably contributing to the perpetuation of chronic inflammation, in the presence of specific autoimmunity. | 22284820 |
| Refractory anemias, Inflammation | Altered Intercellular Communication | The presence of synovial CP was almost exclusive in RA compared with healthy synovium and correlated with the degree of local inflammation. | 22284820 |
| Inflammation | Altered Intercellular Communication | Synovial citrullination and PAD expression are dependent on local inflammation and targeted by glucocorticoids. | 22284820 |
| Inflammation, Chronic Kidney Diseases | Altered Intercellular Communication | The effects of fish oil supplementation on markers of inflammation in chronic kidney disease patients. | 22285316 |
| Inflammation, Traumatic injury | Altered Intercellular Communication | Early trauma and inflammation: role of familial factors in a study of twins. | 22286843 |
| Inflammation, Traumatic injury | Altered Intercellular Communication | Although early trauma (trauma in childhood) has been linked to adult inflammation and adult disease of inflammatory origin, it remains unknown whether this relationship is due to long-term consequences of early life stress or other familial factors. | 22286843 |
| Inflammation, Traumatic injury | Altered Intercellular Communication | The link between early trauma and inflammation is largely explained by familial factors shared by the twins because levels of inflammation were highest when both twins were exposed to trauma. | 22286843 |
| Inflammation | Altered Intercellular Communication | Clarification of familial factors associated with early stress and adult inflammation will be important to uncover correlates of stress and disease. | 22286843 |
| Tissue Adhesions | Altered Intercellular Communication | Inflammation/polyp recurrence, adhesions, and middle turbinate lateralization are causes of suboptimal outcomes following sinus surgery and lead to increased rates of revision. | 22287304 |
| Inflammation, polyps, Tissue Adhesions | Altered Intercellular Communication | Efficacy endpoints included assessment of inflammation, polyp formation, adhesions, and middle turbinate position. | 22287304 |
| Inflammation, Craniosynostosis | Altered Intercellular Communication | Persistence of respiratory viruses within the sinonasal mucosa is unlikely to be a cause of ongoing inflammation in CRS. | 22287325 |
| Inflammation, Paranasal Sinus Disorder | Altered Intercellular Communication | Collecting mucosal biopsies is invasive and creates additional inflammation, hampering a better understanding of nasal and sinus disease evolution and response to treatment. | 22287327 |
| Inflammation, Infection caused by Helicobacter pylori, Endothelium, Vascular | Altered Intercellular Communication | As default, Helicobacter pylori infection may cause systemic inflammation and vascular endothelial damage. | 22287400 |
| Inflammation, Helicobacter pylori, Prediabetes syndrome | Altered Intercellular Communication | Diabetics infected with Helicobacter pylori had significantly higher inflammation marker levels than non-infected patients (p<0.05). | 22287400 |
| Primary malignant neoplasm | Altered Intercellular Communication | Our findings suggested that ROS produced by neutrophils universally reflects the systemic inflammatory condition in cancer patients. | 22287746 |
| Liver carcinoma | Altered Intercellular Communication | Inflammation-based prognostic score for hepatocellular carcinoma patients on sorafenib treatment. | 22287754 |
| Malignant neoplasm of liver, FAM126A gene, Hypoalbuminemia | Altered Intercellular Communication | In 81 patients receiving sorafenib treatment for advanced HCC, we evaluated the prognostic significance of an inflammation-based prognostic score, the Glasgow prognostic score [evidenced by an elevated C-reactive protein level (>1.0 mg/dl) and hypoalbuminemia (<3.5 g/dl)] and compared it with Child-Pugh grade, Barcelona Clinic Liver Cancer staging system, Japan Integrated Staging (JIS) score, and the performance status by Cox-proportional analysis. | 22287754 |
| Inflammation, Granuloma, Tuberculosis, Fibrosis Assessment, Mycobacterium Infections | Altered Intercellular Communication | As opposed to tuberculosis the morphology of mycobacteriosis is more homogeneous and includes inflammation with epithelioid giant-cell granuloma and fibrosis, pneumogenic and bronchogenic cavernous cavities, mycobacterial endobronchitis. | 22288163 |
| Inflammation | Altered Intercellular Communication | [Influence of biological features of pathogens on maxillary sinus mucous chronic inflammation]. | 22288165 |
| ARCN1 gene, Inflammation, Colonization, Necrosis, Chronic Obstructive Airway Disease | Altered Intercellular Communication | Chronic inflammation and reduced airways integrity in chronic obstructive pulmonary disease (COPD) potentially results from secondary necrosis as a result of impaired phagocytosis of apoptotic material by airway macrophages, and increased bacterial colonization. | 22288725 |
| ARCN1 gene, Inflammation, Exacerbation, Necrosis | Altered Intercellular Communication | Improved clearance of both apoptotic cells and bacteria in the airway may have a dual effect; reducing the risk of secondary necrosis and release of toxic cell contents that perpetuate inflammation as well as contributing to a reduction in the rate of exacerbations in COPD. | 22288725 |
| ARCN1 gene, Inflammation, Chronic Obstructive Airway Disease | Altered Intercellular Communication | Chronic obstructive pulmonary disease (COPD) is associated with systemic inflammation and oxidative stress. | 22288943 |
| Inflammation, Myeloid Leukemia, Chronic | Altered Intercellular Communication | N(e) -(carboxymethyl) lysine (CML), an advanced glycation end product (AGE) and the soluble decoy receptor, sRAGE, are exciting new molecules linked to oxidative stress and inflammation. | 22288943 |
| Inflammation, Myeloid Leukemia, Chronic | Altered Intercellular Communication | A lack of clear association between sRAGE, CML and systemic inflammation is furthermore evident. | 22288943 |
| Inflammation | Altered Intercellular Communication | Platelet-derived growth factor D (PDGF-D) plays an important role in angiogenesis, vessel remodeling, inflammation and repair in response to injury. | 22289441 |
| Communicable Diseases, Inflammation, Hepatitis C | Altered Intercellular Communication | Chronic inflammation from hepatitis C virus (HCV) infection is not considered to be one of these variables. | 22289876 |
| Inflammation, Liver Stiffness | Altered Intercellular Communication | In a multivariate analysis, inflammation (based on histologic analysis) and level of alanine aminotransferase (ALT) were associated with liver stiffness. | 22289876 |
| Inflammation, Liver Cirrhosis | Altered Intercellular Communication | The chances of a patient having a level of stiffness that indicates cirrhosis increased with grade of inflammation and level of ALT. | 22289876 |
| Inflammation, Liver Cirrhosis | Altered Intercellular Communication | By using a conservative 14.5-kPa cutoff for the diagnosis of cirrhosis, grade 3 inflammation had an odds ratio of 9.10 (95% confidence interval, 2.49-33.4). | 22289876 |
| Liver Stiffness | Altered Intercellular Communication | Inflammation should be considered a confounding variable in analysis of liver stiffness. | 22289876 |
| Inflammation, Sardinian language | Altered Intercellular Communication | A genome-wide association scan on the levels of markers of inflammation in Sardinians reveals associations that underpin its complex regulation. | 22291609 |
| Inflammation, Metabolic Syndrome X, ETV3 wt Allele | Altered Intercellular Communication | Low sex hormone-binding globulin (SHBG) is associated with metabolic syndrome (MetS), but its relationship with inflammation is unclear. | 22293276 |
| Inflammation, Metabolic Syndrome X, ETV3 wt Allele | Altered Intercellular Communication | Low sex hormone-binding globulin (SHBG) is associated with metabolic syndrome (MetS), but its relationship with inflammation is unclear. | 22293276 |
| Inflammation, Electrocardiogram: myocardial infarction (finding) | Altered Intercellular Communication | We investigated whether ELOVL polymorphisms are associated with adipose tissue fatty acids, serum lipids, inflammation and ultimately with nonfatal myocardial infarction (MI) in a Costa Rican population. | 22293571 |
| Inflammation, Hypercalcemia, CTCAE | Altered Intercellular Communication | Granulomatous inflammation of the skin and lymph nodes induced by intravenous or injectable silicone is a rare condition of hypercalcemia that is usually not within the scope of differential diagnosis. | 22293885 |
| Inflammation, Hypercalcemia, CTCAE | Altered Intercellular Communication | Topical applied liquid silicone by means of a focal ultrasound device induced extensive granulomatous inflammation of the skin and local lymph nodes, being the underlying cause for hypercalcemia in this case. | 22293885 |
| Necrotizing granulomatous inflammation | Altered Intercellular Communication | This is the first time that a transdermal silicone treatment has been reported to cause severe granulomatous tissue inflammation. | 22293885 |
| Airway structure | Altered Intercellular Communication | Airway inflammation is a critical regulator of disease outcome in RSV infected hosts. | 22295065 |
| Inflammation, Respiratory Syncytial Virus Infections, Bronchiolitis, Inflammatory disorder | Altered Intercellular Communication | Although "controlled" inflammation is required for virus clearance, aberrant and exaggerated inflammation during RSV infection results in development of inflammatory diseases like pneumonia and bronchiolitis. | 22295065 |
| Inflammation | Altered Intercellular Communication | Interleukin-1b (IL-1b) plays an important role in inflammation by orchestrating the pro-inflammatory response. | 22295065 |
| ARCN1 gene, Inflammation | Altered Intercellular Communication | 25-HC production was enhanced in the airways of COPD patients and may play a role in neutrophilic inflammation. | 22295989 |
| Acute inflammation | Altered Intercellular Communication | Our data demonstrate that bacteria-related active inflammation results in a sharp increase of DMBT1 levels in enterocytes. | 22296301 |
| ARCN1 gene, Inflammation, Bronchial Obstruction | Altered Intercellular Communication | The results suggest that the relationships between reduced lung function, COPD and CVD are complex and not only linked to bronchial obstruction and low-grade systemic inflammation. | 22296632 |
| Inflammation, Fibrosis Assessment | Altered Intercellular Communication | Different MCAS presentations reflect elaboration of different mediators, some of which can induce inflammation and fibrosis. | 22296862 |
| Peripheral Vascular Diseases, Inflammation | Altered Intercellular Communication | Supplementation with Omega-3 fatty acids had no affect on platelet and endothelial activation or markers of inflammation in patients with peripheral arterial disease. | 22296885 |
| Inflammation, Caseous necrosis | Altered Intercellular Communication | The histopathology showed granulomatous inflammation with caseous necrosis. | 22299474 |
| Inflammation | Altered Intercellular Communication | Intimal thickness and cellularity, together with inflammation consisting of plasma cells were increased in C4d- as compared with C4d + (p < 0.05). | 22300108 |
| Tumor necrosis, Inflammation, Metabolic Syndrome X | Altered Intercellular Communication | Serum LCN2 levels were also compared with several indicators for metabolic syndrome, and with serum levels of interleukin (IL)-6 and tumour necrosis factor (TNF)-a, two markers of inflammation. | 22300286 |
| Inflammation, Psoriasis | Altered Intercellular Communication | Serum LCN2 levels are a general indicator for increased inflammation in the patients with psoriasis. | 22300286 |
| Conjunctivitis, Keratitis, Keratoconjunctivitis Sicca | Altered Intercellular Communication | Rarely, LP affects the conjunctiva, resulting in conjunctival inflammation, cicatrization and scarring of the subepithelium and cornea, causing keratitis and keratoconjunctivitis sicca. | 22300330 |
| ARCN1 gene, Tumor necrosis, Inflammation | Altered Intercellular Communication | This study sought to evaluate the systemic inflammatory profile associated with COPD and to assess the impact of tumor necrosis factor neutralization on systemic inflammation. | 22300528 |
| Inflammation, Necrosis | Altered Intercellular Communication | Because anti-tumor necrosis factor-alpha did not influence systemic inflammation, how to control the underlying pathology beyond symptom suppression remains unclear. | 22300528 |
| Inflammation, Transplant glomerulopathy | Altered Intercellular Communication | Microcirculation inflammation sum score predicted graft failure independently of time, C4d and transplant glomerulopathy. | 22300601 |
| Inflammation, Graft failure | Altered Intercellular Communication | Thus any degree of microcirculation inflammation in late kidney transplant biopsies strongly indicates presence of DSA and predicts progression to graft failure. | 22300601 |
| Inflammation | Altered Intercellular Communication | The dermis was notable for dilated eccrine ducts and absent inflammation. | 22301047 |
| Multiple polyps, Craniosynostosis, Tissue Adhesions, Acute inflammation, Chronic sinusitis | Altered Intercellular Communication | Endoscopic sinus surgery (ESS) for chronic rhinosinusitis (CRS) may be compromised by postoperative inflammation, polyposis, and adhesions, often requiring subsequent intervention. | 22301107 |
| Inflammation | Altered Intercellular Communication | All of our patients had coexisting chronic illnesses associated with inflammation, as well as detectable HIV viral loads and CD4 count >200, suggesting a role for both HIV- and non-HIV-associated inflammation in HIV-HL pathogenesis in this population. | 22302202 |
| Inflammation, Malignant Neoplasms | Altered Intercellular Communication | Angiogenesis and inflammation are both important to the pathogenesis of malignancies. | 22302227 |
| Inflammation | Altered Intercellular Communication | Nuclear factor-kB (NF-kB) signaling plays critical roles in physiological and pathological processes such as responses to inflammation and oxidative stress. | 22302838 |
| Inflammation, Ischemic stroke, COL4A2 wt Allele | Altered Intercellular Communication | The results suggest that the relationships with inflammation for ischaemic stroke and ICH are different. | 22303818 |
| Inflammation, Swelling | Altered Intercellular Communication | Although eight-week old normal mice inoculated in the hind footpad developed no hind limb swelling with either virus, CHIKV-LR replicated in musculoskeletal tissues and caused detectable inflammation. | 22305131 |
| Inflammation, Dental Plaque | Altered Intercellular Communication | It has been suggested that these bacteria might contribute to inflammation and plaque instability. | 22305832 |
| Inflammation, Dental Plaque, Blood Circulation | Altered Intercellular Communication | We assumed that if periodontal bacteria induce inflammation of plaque, the bacteria would be released into the bloodstream when vulnerable plaque ruptures. | 22305832 |
| Inflammation, Dental Plaque | Altered Intercellular Communication | This raises the possibility that such bacteria are latently present in plaque and also suggests that these bacteria might have a role in plaque inflammation and instability. | 22305832 |
| vascular inflammations | Altered Intercellular Communication | Pentraxin-3 (PTX3) is an inflammatory marker thought to be more specific to vascular inflammation than C-reactive protein (CRP). | 22305847 |
| Inflammation, Choline Dehydrogenase, Mitochondrial | Altered Intercellular Communication | Among persons with stable CHD, higher PTX3 concentrations were associated with increased risk for all-cause mortality, CV events, and incident HF independently of systemic inflammation. | 22305847 |
| Inflammation, Angina Pectoris | Altered Intercellular Communication | Platelet activation and inflammation have been recognized during AMI and stable angina (SA). | 22306248 |
| Inflammation, Fibrosis Assessment, Autoimmune Chronic Hepatitis, Hepatitis | Altered Intercellular Communication | Biopsy specimens showed not only centrizonal inflammation but also interface hepatitis and bridging fibrosis, which were characteristic of autoimmune hepatitis. | 22306547 |
| Inflammation | Altered Intercellular Communication | Surgical cardiac revascularization produces a high degree of systemic inflammation and the secretion of several cytokines. | 22306617 |
| Inflammation, Organ Dysfunction Scores, Atrial Fibrillation by ECG Finding | Altered Intercellular Communication | Intensive postoperative inflammation may increase the incidence of postoperative atrial fibrillation and favor organ dysfunctions. | 22306617 |
| acetylglucosamine | Altered Intercellular Communication | Our results demonstrate that the absence of aGlcNAc triggers gastric tumorigenesis through inflammation-associated pathways in vivo. | 22307328 |
| Inflammation, Stomach Carcinoma, Infection caused by Helicobacter pylori | Altered Intercellular Communication | Thus, aGlcNAc-terminated gastric mucin plays dual roles in preventing gastric cancer by inhibiting H. pylori infection and also suppressing tumor-promoting inflammation. | 22307328 |
| Inflammation, Atherosclerosis | Altered Intercellular Communication | Our results suggest the impact of PSGL-1 Met62Ile polymorphism on inflammation in advanced atherosclerosis. | 22307784 |
| Inflammation, Electrocardiogram: myocardial infarction (finding), Necrosis | Altered Intercellular Communication | Baseline NT-proBNP and biomarkers of inflammation and necrosis in patients with ST-segment elevation myocardial infarction: insights from the APEX-AMI trial. | 22307842 |
| Inflammation | Altered Intercellular Communication | This finding is consistent with pre-clinical and clinical research suggesting that systemic inflammation may influence NT-proBNP expression independently of myocardial stretch. | 22307842 |
| Inflammation, Atrial Fibrillation by ECG Finding | Altered Intercellular Communication | Although inflammation appears to play a pivotal role in the pathophysiology of atrial fibrillation (AF), the source of inflammation is unknown. | 22308085 |
| Inflammation, Traumatic injury, Myocarditis, CTCAE 5.0 | Altered Intercellular Communication | Whether TSP-2 may affect cardiac inflammation and injury, in particular during acute viral myocarditis, is completely unknown. | 22308237 |
| Inflammation, Myocarditis, CTCAE 5.0 | Altered Intercellular Communication | Therefore, mortality, cardiac inflammation, and function were assessed in TSP-2-null (KO) and wild-type (WT) mice in human Coxsackie virus B3 (CVB3)-induced myocarditis. | 22308237 |
| Inflammation, Depressed mood, Traumatic injury, Cardiac dilatation | Altered Intercellular Communication | The absence of TSP-2 resulted in increased cardiac inflammation and injury at 14 days, which resulted in depressed systolic function [fractional shortening (FS); 34 +- 2.6 in WT vs. 24 +- 1.8 in KO mice, P< 0.05] and increased cardiac dilatation (end-diastolic dimensions, mm; 3.7 +- 0.09 in WT vs. 4.8 +- 0.06 in KO mice, P< 0.05) 35 days post-infection. | 22308237 |
| Communicable Diseases, Inflammation, Traumatic injury | Altered Intercellular Communication | Finally, overexpression of TSP-2 in WT hearts using cardiotropic vectors derived from adeno-associated virus serotype 9 (AAV9) inhibited cardiac inflammation and injury at 14 days and improved cardiac function at 35 days post-CVB3 infection when compared with control AAV9. | 22308237 |
| Inflammation, physiopathological, Traumatic injury, Acute myocarditis | Altered Intercellular Communication | TSP-2 has a protective role against cardiac inflammation, injury, and dysfunction in acute viral myocarditis. | 22308237 |
| Inflammation | Altered Intercellular Communication | A strong link between C5a, nucleosomes, and FSAP activity indicates that this new principle might be important in the regulation of inflammation. | 22308306 |
| Inflammation, Periodontitis, Gingival Hyperplasia | Altered Intercellular Communication | The incidence of chronic periodontitis in this age group is also high and the Ca antagonist medication in those individuals might substantially modify the clinical course of periodontal inflammation leading to gingival enlargement and hypertrophic pocket wall. | 22308953 |
| Achalasia, Inflammation, Neuropathy | Altered Intercellular Communication | The etiology of achalasia is believed to be the neuropathy associated with chronic inflammation of the nerve plexus, but the cause of plexus inflammation is unknown. | 22309323 |
| Superficial ulcer, Inflammation, Congenital hypotrichia, Fissure in skin, Ectoderm, Keratoderma, Palmoplantar, Fragile skin | Altered Intercellular Communication | Mutations in PKP1 may manifest with skin fragility and erosions, patches of scale crust on the trunk and limbs, peri-oral cracking and inflammation, hypotrichosis, palmoplantar keratoderma with painful fissuring and other somewhat variable ectodermal anomalies. | 22309335 |
| Inflammation, Cyclophosphamide/Vincristine/Dacarbazine Regimen, Cardiovascular Diseases | Altered Intercellular Communication | C-reactive protein (CRP) is an acute-phase marker of systemic inflammation and considered an established risk marker for cardiovascular disease (CVD) in old age. | 22309883 |
| Necrotizing granulomatous inflammation, Necrosis | Altered Intercellular Communication | CD is characterized by a chronic granulomatous inflammation by necrotic scarring with aspects of full-thickness wall. | 22309886 |
| Inflammation, Malnutrition | Altered Intercellular Communication | The only significant determinants of SPhA were malnutrition (85*4%; P<0*0001) and inflammation (9*6 %; P<0*0001). | 22309898 |
| Inflammation, Malnutrition | Altered Intercellular Communication | In conclusion, next to the established predictors, malnutrition and inflammation have a strong impact on PhA in sick individuals, which partly explains its prognostic power. | 22309898 |
| Inflammation, Malnutrition | Altered Intercellular Communication | When investigating the SPhA, only malnutrition and inflammation were found to be significant predictors, as a result of which the SPhA is considered a more suitable indicator of nutritional and health status. | 22309898 |
| Myelolipoma, Hyperplasia, Adrenal Cortex Diseases | Altered Intercellular Communication | Patients with adrenal cortex disorders, such as hyperplasias and neoplasms, particularly when associated with hormonal imbalances, may have an increased risk of developing myelolipomas. | 22309953 |
| Inflammation, Non-ST Elevation Myocardial Infarction by ECG Finding | Altered Intercellular Communication | The results are in concordance with previous data on non-STEMI patients, implying that a HLA-DRB1*01--related haplotype increases the risk of CAD, possibly though increased inflammation. | 22310063 |
| Inflammation | Altered Intercellular Communication | The impact of insulin resistance and inflammation on the association between sarcopenic obesity and physical functioning. | 22310233 |
| Interstitial inflammation | Altered Intercellular Communication | Interstitial inflammation was present in 25 biopsy specimens. | 22310621 |
| Inflammation, Panuveitis | Altered Intercellular Communication | Medications such as corticosteroids and immunosuppressive agents are used to reduce inflammation in patients with posterior or panuveitis. | 22310876 |
| Inflammation | Altered Intercellular Communication | However, abnormal delayed enhancement MRI (consistent with inflammation) was present in both the thickened and the normal pericardial segments. | 22311855 |
| Inflammation | Altered Intercellular Communication | The corrected visual acuity OD dropped to 0.06 due to anterior chamber inflammation and the intraocular pressure increased to 26 mmHg. | 22312815 |
| Inflammatory Bowel Diseases, Colorectal Carcinoma | Altered Intercellular Communication | Associations are well established between intestinal infection/inflammation or inflammatory bowel diseases and colorectal cancer (CRC). | 22314042 |
| Pancreatitis, Acute, Inflammation | Altered Intercellular Communication | Systemic inflammation affects hemostasis during severe acute pancreatitis (SAP). | 22314345 |
| Inflammation, Fibrosis Assessment, Non-alcoholic Fatty Liver Disease | Altered Intercellular Communication | The main outcomes of the study were to assess whether IL28B rs12979860 and rs8099917 polymorphisms, together with PNPLA3 rs738409 C>G polymorphism, are associated with lobular inflammation and fibrosis, in NAFLD patients. | 22314430 |
| Inflammation, Fatty degeneration, Hyperuricemia | Altered Intercellular Communication | Multivariate logistic regression analysis showed that age (OR 1.043, 95% CI 1.012-1.075, p=0.007), triglycerides (OR 1.005, 95% CI 1.000-1.010, p=0.04), hyperuricemia (OR 5.027, 95% CI 1.839-13.742, p=0.002), IL28B rs12979860 TT/TC (OR 0.219, 95% CI 0.101-0.472, p<0.001), and steatosis grade (OR 1.704, 95% CI 1.048-2.773, p=0.03) were independently linked to moderate-severe lobular inflammation. | 22314430 |
| Inflammation, Fibrosis Assessment | Altered Intercellular Communication | Finally, IL28B rs12979860 CC was associated with severe fibrosis (F3-F4) on univariate analysis, even if only older age (OR 1.064, 95% CI 1.026-1.104, p=0.001), high HOMA (OR 1.213, 95% CI 1.068-1.377, p=0.003), and lobular inflammation (OR 3.181, 95% CI 1.438-7.036, p=0.004), remained associated in multivariate logistic regression analysis. | 22314430 |
| Inflammation, Overweight | Altered Intercellular Communication | In addition to adipose tissue, recent studies suggest that skeletal muscle may also be a source of low-grade inflammation, particularly in inactive and/or overweight individuals. | 22314623 |
| Parkinson Disease, Inflammation, Fibrosis Assessment | Altered Intercellular Communication | Histological study confirmed the diagnosis of idiopathic Parkinson's disease, and there was striking, dense collagenous fibrosis at the distal end of the right DBS lead associated with focal hemosiderin deposition, chronic inflammation, and mild gliosis. | 22314706 |
| ACSM3 gene, Pituitary Hormones, Anterior | Altered Intercellular Communication | SAH is associated with anterior pituitary dysfunction and GH is the most frequently found deficient hormone in the patients. | 22315089 |
| Metabolic Syndrome X | Altered Intercellular Communication | Male sex hormones play an important role in ED and variety of TDS and may have influence on the development of metabolic syndrome. | 22315154 |
| Inflammation, diabetic | Altered Intercellular Communication | Enterovirus RNA was found in diabetic patients more frequently than in control subjects and was associated with a clear inflammation response in the gut mucosa. | 22315304 |
| Communicable Diseases, Inflammation, diabetic | Altered Intercellular Communication | The results suggest that a large proportion of type 1 diabetic patients have prolonged/persistent enterovirus infection associated with an inflammation process in gut mucosa. | 22315304 |
| IL13 gene | Altered Intercellular Communication | Allergic rhinitis is a common upper respiratory tract inflammation associated with a significant morbidity in all the age groups. | 22315746 |
| Inflammation, Meckel Diverticulum, Gangrene | Altered Intercellular Communication | Histopathological examination of these specimens confirmed 2 cases with inflammation, one with gangrene and one ulcerated gastric mucosa in the Meckel's diverticulum. | 22315842 |
| Delirium, Inflammation | Altered Intercellular Communication | The cholinergic system and inflammation: common pathways in delirium pathophysiology. | 22316182 |
| Communicable Diseases, Inflammation | Altered Intercellular Communication | Vaginal pH is related to genital tract inflammation and changes in the bacterial flora, both suggested cofactors for persistence of human papillomavirus (HPV) infection. | 22316377 |
| Inflammation, Hypercapnia, Carotid Intima-Media Thickness, Thrombophilia, Atherosclerosis, Hypoxia, Endothelial dysfunction, Hypertension, CTCAE, Hyperactive behavior | Altered Intercellular Communication | Its pathophysiological consequences (hypoxia, hypercapnia, micro-arousals, sympathetic hyperactivity, oxidative stress, systemic inflammation and hyper-coagulability) are implicated in the development of hypertension, endothelial dysfunction and higher intima-media thickness (IMT) values, all elements known to lead to atherosclerosis. | 22317765 |
| Inflammation, Inflammatory lung disease, Hemoptysis | Altered Intercellular Communication | Serum vascular endothelial growth factor and angiopoietin-2 are associated with the severity of systemic inflammation rather than the presence of hemoptysis in patients with inflammatory lung disease. | 22318826 |
| Inflammation, Hypoxia | Altered Intercellular Communication | Vascular endothelial growth factor (VEGF) and angiopoietin-2 (Ang-2) are major mediators of angiogenesis and are induced by tissue inflammation and hypoxia. | 22318826 |
| Inflammation, Inflammatory disorder, Hemoptysis | Altered Intercellular Communication | The purpose of this study was to investigate whether serum VEGF and Ang-2 are associated with the presence of hemoptysis and the extent of systemic inflammation in patients with inflammatory lung diseases. | 22318826 |
| Inflammation, Inflammatory disorder, Hemoptysis | Altered Intercellular Communication | Our study suggests that serum VEGF and Ang-2 levels are associated with PaO2 and the severity of inflammation rather than the presence of hemoptysis in patients with inflammatory lung diseases. | 22318826 |
| Inflammation, Observation Method - Coagulation | Altered Intercellular Communication | Markers of inflammation and coagulation may be modulated by enteral feeding strategy. | 22318965 |
| Acute respiratory failure, Observation Method - Coagulation, Inflammation, Critical Illness | Altered Intercellular Communication | EN strategy in critically ill patients with acute respiratory failure does not significantly modify inflammation and coagulation by day 6, but trophic feeds may have some modest effects in attenuating inflammation and coagulation. | 22318965 |
| Inflammation | Altered Intercellular Communication | This gene dense region plays an important role in inflammation, immunity, and self-cell recognition. | 22319020 |
| Inflammation, Atherosclerosis | Altered Intercellular Communication | MHC genes regulate inflammation and T-cell responses that contribute importantly to the initiation and propagation of atherosclerosis. | 22319020 |
| vascular inflammations, Atherosclerosis | Altered Intercellular Communication | Recently, pentraxin-3 (PTX3) has been proposed to be a specific marker of vascular inflammation, yet its association with atherosclerosis is still unclear. | 22319633 |
| Inflammation, vascular inflammations | Altered Intercellular Communication | Unlike C-reactive protein, PTX3 is not a component of the classic acute phase response (systemic inflammation) but appears to be more specific for vascular inflammation. | 22319633 |
| Inflammation, Ulcer | Altered Intercellular Communication | The patient was in precarious hygienic condition, and was suffering from localized ulcerated foot ulcers with significant inflammation extending up to the knee. | 22320020 |
| Inflammation | Altered Intercellular Communication | In all these abnormalities, infection/inflammation has been implicated. | 22321000 |
| Rupture, Inflammation, Leucocytic infiltrate, Stenosis Morphology, Dental Plaque | Altered Intercellular Communication | The major morphological characteristics of vulnerable plaque are big lipid core, thin fibrous cap, inflammatory infiltration, neovascularization, severe stenosis, plaque rupture, and endothelial denudation suggesting inflammation performed an important role in the formation of vulnerable plaque. | 22321226 |
| Autoimmune Diseases, Inflammation, Rheumatoid Arthritis | Altered Intercellular Communication | [Association between systemic inflammation and autoimmunity parameters and plasma lipid in patients with rheumatoid arthritis]. | 22321280 |
| Refractory anemias, Inflammation, Rheumatoid Arthritis | Altered Intercellular Communication | The purpose of this study was to observe the association between inflammation status/autoimmune antibodies and plasma lipid in patients with rheumatoid arthritis (RA). | 22321280 |
| Rheumatoid Arthritis, Inflammation | Altered Intercellular Communication | This study showed that rheumatoid arthritis is associated with an abnormal lipid profile, especially in patients with increased inflammation markers and autoimmune antibodies. | 22321280 |
| Inflammation, Cyclophosphamide/Vincristine/Dacarbazine Regimen | Altered Intercellular Communication | It is believed that the one cause of CVD is red blood cell extravasation and local iron overload that could generate free radicals and iron-dependent inflammation. | 22321300 |
| Chronic Obstructive Airway Disease, Pneumonitis | Altered Intercellular Communication | [The clinical characteristics of intra-acinar pulmonary artery inflammation and its effect on clinical parameters in smokers with normal lung function and patients with chronic obstructive pulmonary disease]. | 22321324 |
| ARCN1 gene, Chronic Obstructive Airway Disease, Pneumonitis | Altered Intercellular Communication | To study the pathological characteristics of intra-acinar pulmonary artery inflammation and its correlation with smoking index and disease progression in smokers with normal lung function and smokers with chronic obstructive pulmonary disease (COPD). | 22321324 |
| ARCN1 gene | Altered Intercellular Communication | (1) Pulmonary arterial inflammation appears in smokers with normal lung function and smokers with COPD patients. | 22321324 |
| Inflammation | Altered Intercellular Communication | The patients with greater SDIs had lower Z-scores, which suggests a direct association between chronic inflammation from disease and a reduced BMD. | 22321657 |
| Inflammation, Fibrosis Assessment, Compression, Distortion | Altered Intercellular Communication | We postulate that age-related CC may predispose to OD and stress-induced FRFx, and that inflammation, fibrosis, and anatomic distortion in the surrounding soft tissues may contribute to SCV compression. | 22322117 |
| Inflammation, Lupus Erythematosus, Systemic, Autoimmune Diseases, Tissue damage, Lupus Erythematosus | Altered Intercellular Communication | Systemic lupus erythematosus (SLE) is an autoimmune disease that results in inflammation and tissue damage. | 22323338 |
| Inflammation, Neoplasms | Altered Intercellular Communication | Pathologic analyses revealed that all of the resected or biopsied seminal vesicle tissues had chronic nonspecific inflammation in the seminal vesicle wall, and no tumors were identified. | 22323622 |
| Inflammation | Altered Intercellular Communication | A biopsy from the site revealed chronic caseating granulomatous inflammation, positive for BCG Tokyo-172 strain on the multiplex polymerase chain reaction. | 22323874 |
| Inflammatory abnormality of the eye, Papilledema | Altered Intercellular Communication | While the ocular inflammation responded to high doses of oral prednisolone, the disc edema showed little improvement. | 22323889 |
| Inflammatory abnormality of the eye, Papilledema | Altered Intercellular Communication | After oral administration of methotrexate, the disc edema and ocular inflammation were resolved, and the dose of oral corticosteroid could be reduced. | 22323889 |
| Inflammation, Rheumatoid Arthritis | Altered Intercellular Communication | Chronic inflammation in rheumatoid arthritis is associated with vascular endothelial dysfunction. | 22324946 |
| Refractory anemias, Inflammation, Endothelial dysfunction | Altered Intercellular Communication | In RA, endothelial dysfunction is part of the disease process and is mediated by AGEs-induced inflammation. | 22324946 |
| Inflammation, Obesity | Altered Intercellular Communication | Epicardial fat, cardiac dimensions, and low-grade inflammation in young adult monozygotic twins discordant for obesity. | 22325087 |
| Inflammation, Obesity | Altered Intercellular Communication | We studied the relations among acquired obesity, low-grade inflammation, and genetic factors in the accumulation of epicardial fat. | 22325087 |
| Inflammation, Obesity, Cardiovascular Diseases | Altered Intercellular Communication | The close relation between epicardial fat and low-grade inflammation is likely to contribute to the development of cardiovascular disease in obesity. | 22325087 |
| Gastrointestinal inflammation | Altered Intercellular Communication | The neutrophil protein calprotectin has been investigated as a surrogate marker for intestinal inflammation. | 22325175 |
| Refractory anemias, Inflammation, Atherosclerosis | Altered Intercellular Communication | Many studies have shown subclinical atherosclerosis in RA is associated with CV risk factors and inflammation. | 22325679 |
| Sleep Apnea, Obstructive, Erectile dysfunction | Altered Intercellular Communication | Literature review suggests that OSAS induces a spectrum of abnormalities in neural, hormonal and vascular regulation that contribute to the development of ED (erectile dysfunction). | 22325836 |
| Inflammation, Autistic Disorder, Abnormality of mitochondrial metabolism | Altered Intercellular Communication | Oxidative stress, inflammation and mitochondrial dysfunction have all been suggested to play key roles in autism and may be linked via alterations in cellular redox homeostasis. | 22325990 |
| nervous system disorder, Inflammation, Complications of Diabetes Mellitus, Abnormality of mitochondrial metabolism | Altered Intercellular Communication | Both MG and AGEs can induce oxidative stress, inflammation and mitochondrial dysfunction and are implicated in diabetic complications and multiple, age-related neurological diseases. | 22325990 |
| Inflammation, Primary malignant neoplasm | Altered Intercellular Communication | The connection between cancer and inflammation is widely recognized, yet the underlying molecular mechanisms are poorly understood. | 22326055 |
| Inflammation, Primary malignant neoplasm | Altered Intercellular Communication | We report here that TIPE2 provides a molecular bridge from inflammation to cancer by targeting the Ras signaling pathway. | 22326055 |
| Inflammation, Primary malignant neoplasm, Inflammatory disorder | Altered Intercellular Communication | Thus, TIPE2 is an inhibitor of both inflammation and cancer, and a potential drug target for inflammatory and neoplastic diseases. | 22326055 |
| Inflammation, Endotoxemia, Metabolic Syndrome X | Altered Intercellular Communication | Endotoxemia, characterized by an excess of circulating bacterial wall lipopolysaccharide, is associated with systemic inflammation and the metabolic syndrome. | 22326433 |
| Inflammation, Endotoxemia, Gastrointestinal Diseases, Metabolic Syndrome X | Altered Intercellular Communication | Therapeutic reagents that reduce endotoxemia might reduce systemic inflammation in patients with gastrointestinal diseases or metabolic syndrome. | 22326433 |
| Degenerative polyarthritis, Inflammation | Altered Intercellular Communication | Effusion status was determined by clinical examination, radiographs were scored for OA changes, and inflammation grading used haematoxylin and eosin stained sections of synovium. | 22326896 |
| Inflammation, Stomach Carcinoma, precancerous lesions | Altered Intercellular Communication | So, our results indicated that the IL-1RN*2 allele may increase the risk of gastric cancer and precancerous lesions in the Southeast Brazilian population, reinforcing the importance of host genetic factors in the susceptibility to gastric cancer and the participation of cytokines in both the inflammation and the carcinogenic process. | 22327782 |
| Necrotizing enterocolitis in fetus OR newborn, Inflammation, Necrosis | Altered Intercellular Communication | During NEC pathogenesis, bacteria are able to penetrate innate immune defenses and invade the intestinal epithelial layer, causing subsequent inflammation and tissue necrosis. | 22328592 |
| Inflammation, Electrocardiogram: myocardial infarction (finding) | Altered Intercellular Communication | Anti-apolipoprotein A-1 IgG in patients with myocardial infarction promotes inflammation through TLR2/CD14 complex. | 22329401 |
| vascular inflammations, Cardiovascular Diseases | Altered Intercellular Communication | Toll-like receptor (TLR)-mediated vascular inflammation, inducible by - amongst other factors - auto-antibodies, is increasingly recognized as a potential mediator of cardiovascular disease. | 22329401 |
| Inflammation | Altered Intercellular Communication | These auto-antibodies promote inflammation by stimulating the TLR2/CD14 receptor complex, probably because of molecular mimicry, which may contribute to atherosclerosis-related complications in patients. | 22329401 |
| Inflammation | Altered Intercellular Communication | In this respect, physical activity may promote neuronal resilience by reducing inflammation. | 22329653 |
| Familial spinal arachnoiditis, Inflammation, Fibrosis Assessment | Altered Intercellular Communication | Spinal arachnoiditis is a rare disease caused by fibrosis and adhesion of the arachnoid membrane due to chronic inflammation. | 22330119 |
| Gastroesophageal reflux disease | Altered Intercellular Communication | (3) Acid-related sensitization within the gastroesophageal reflux disease population is not dependant on mucosal inflammation. | 22330131 |
| Orbital Pseudotumor | Altered Intercellular Communication | To evaluate the outcomes of patients with idiopathic sclerosing orbital inflammation (ISOI) treated with radiotherapy with or without surgery. | 22331004 |
| Inflammation, Scleritis, Edema, Structure of lamina episcleralis, Rheumatoid Arthritis | Altered Intercellular Communication | Scleritis is a rare, progressive and serious disease, the signs of which are inflammation and edema of episcleral and scleral tissues and is greatly associated with systemic rheumatoid diseases. | 22331111 |
| Inflammation, Asthma, Wheezing | Altered Intercellular Communication | Nasal cell DNA methylation, inflammation, lung function and wheezing in children with asthma. | 22332661 |
| Glycation End Products, Advanced | Altered Intercellular Communication | S100A8/A9 complex is an inflammation-associated biomarker, which binds toll-like receptor 4 and was associated with the receptor for advanced glycation end-products. | 22333479 |
| ARCN1 gene, Inflammation, Pulmonary Hypertension, Tumor necrosis, Chronic Obstructive Airway Disease | Altered Intercellular Communication | The levels of C-reactive protein (CRP), tumor necrosis factor (TNF)-a, brain natriuretic peptide (BNP) and endothelin-1 (ET-1) were investigated to analyze the systemic inflammation in chronic obstructive pulmonary disease (COPD) patients with and without pulmonary hypertension. | 22333502 |
| ARCN1 gene, Inflammation, Pulmonary Hypertension | Altered Intercellular Communication | The level of CRP, ET-1 and BNP were related to pulmonary hypertension in COPD patients, suggesting that systemic inflammation play a role in the pathogenesis of pulmonary hypertension in COPD. | 22333502 |
| Fibrosis, Liver, Portal inflammation, Hepatitis C | Altered Intercellular Communication | High prevalence of autoantibodies to C-reactive protein in patients with chronic hepatitis C infection: association with liver fibrosis and portal inflammation. | 22333691 |
| Inflammation, Fibrosis Assessment, Hepatitis C | Altered Intercellular Communication | We conclude that anti-CRP antibodies are frequently observed in chronic HCV infection and could be a useful marker of advanced fibrosis and portal inflammation. | 22333691 |
| Ulceration, CTCAE, Inflammatory abnormality of the eye | Altered Intercellular Communication | The patient subsequently reported a history of recurrent oral ulceration and intermittent occular inflammation. | 22333754 |
| Inflammation | Altered Intercellular Communication | They predominantly resulted from chronic inflammation of the middle ear. | 22334160 |
| Inflammation, Cerebral abscess | Altered Intercellular Communication | Cerebral abscesses remain one of the most severe complications related with inflammation of the middle ear. | 22334160 |
| Airway structure, Asthma | Altered Intercellular Communication | Chronic airway inflammation in asthmatic patients results in structural airway changes, including angiogenesis. | 22336080 |
| Inflammation, Tumor necrosis, Choline Dehydrogenase, Mitochondrial, Diabetes Mellitus | Altered Intercellular Communication | However, BC was positively associated with markers of inflammation in men with CHD (particularly vascular endothelial growth factor) and in men with diabetes (particularly interleukin-1b and tumor necrosis factor-a). | 22336131 |
| Inflammation, Choline Dehydrogenase, Mitochondrial, Diabetes Mellitus | Altered Intercellular Communication | In an elderly male population, estimated BC exposures were positively associated with markers of systemic inflammation but only in men with CHD or diabetes. | 22336131 |
| Crohn Disease, Inflammation | Altered Intercellular Communication | In Crohn's disease (CD), chronic gut inflammation leads to loss of mucosal barrier integrity. | 22336288 |
| Inflammation | Altered Intercellular Communication | Although previous studies have suggested that inflammation and lipid profile may be involved in those pathophysiological events, it remains controversial to date. | 22336660 |
| Inflammation, Nail Diseases | Altered Intercellular Communication | Our data suggest that DP inflammation is central in the development of psoriatic nail disease. | 22337245 |
| Inflammation, Injury of liver | Altered Intercellular Communication | Among HIV-infected individuals, independent of CD4, HIV-1 RNA, and age, hemoglobin and markers of liver and renal injury are associated with inflammation. | 22337823 |
| Inflammation, Fibrosis Assessment | Altered Intercellular Communication | (2) Pathological inflammation and fibrosis Staging were no statistical difference between two groups patients. | 22338213 |
| Inflammation, Spondylitis | Altered Intercellular Communication | Investigation of two novel biochemical markers of inflammation, matrix metalloproteinase and cathepsin generated fragments of C-reactive protein, in patients with ankylosing spondylitis. | 22339813 |
| Inflammation, Sacroiliac joint structure, Spondylitis | Altered Intercellular Communication | Ankylosing spondylitis (AS) is a chronic inflammation of the spine and the sacroiliac joints. | 22339813 |
| Inflammation | Altered Intercellular Communication | These cleavage products may provide additional information on systemic inflammation as compared to that of full-length CRP. | 22339813 |
| Inflammation | Altered Intercellular Communication | These data suggest that different pools of CRP may provide insight into the inflammation processes in AS. | 22339813 |
| Inflammation | Altered Intercellular Communication | RATIONALE : Preclinical work demonstrates that the transcription factor peroxisome proliferator-activated receptor gamma plays an important role in augmenting phagocytosis while modulating oxidative stress and inflammation. | 22340518 |
| Coughing, Pain Distress Question, Inflammation, Bothered by Vomiting | Altered Intercellular Communication | Symptoms varied between the different anatomical systems, with cough as predominant when concerning aspiration, local pain or inflammation in inhalation and insertion, and vomiting in for the FBs ingestion cases. | 22341887 |
| Inflammation | Altered Intercellular Communication | Systemic inflammation has been considered as one of major pathophysiologic alterations in AECOPD. | 22343073 |
| Inflammation, Traumatic injury, Acute kidney injury | Altered Intercellular Communication | Kidneys with acute injury showed increased expression of 394 transcripts associated with the repair response to injury, including many epithelium-like injury molecules tissue, remodeling molecules, and inflammation molecules. | 22343120 |
| Inflammation | Altered Intercellular Communication | NF-kB is a family of transcription factors that play a central role in mediating cellular response to damage, stress, and inflammation. | 22343279 |
| Inflammation, diabetic | Altered Intercellular Communication | Plasma levels of soluble CD36, platelet activation, inflammation, and oxidative stress are increased in type 2 diabetic patients. | 22343420 |
| Inflammation, Diabetes Mellitus, Non-Insulin-Dependent | Altered Intercellular Communication | Inflammation, oxidative stress, and platelet activation are involved in type 2 diabetes and its complications. | 22343420 |
| Inflammation, Diabetes Mellitus, Non-Insulin-Dependent | Altered Intercellular Communication | sCD36, platelet activation, inflammation, and oxidative stress are increased in type 2 diabetes. | 22343420 |
| Inflammation, Endothelial dysfunction, Stiff toe | Altered Intercellular Communication | Low-grade inflammation, but not endothelial dysfunction, is associated with greater carotid stiffness in the elderly: the Hoorn Study. | 22343535 |
| Inflammation, Endothelial dysfunction, Cardiovascular Diseases | Altered Intercellular Communication | Biomarkers of low-grade inflammation and endothelial dysfunction are associated with cardiovascular disease. | 22343535 |
| Inflammation, Cardiovascular Diseases | Altered Intercellular Communication | Arterial stiffening may be a mechanism through which low-grade inflammation and (or) endothelial dysfunction lead to cardiovascular disease. | 22343535 |
| Inflammation, Endothelial dysfunction, Stiff toe | Altered Intercellular Communication | Therefore, we investigated whether low-grade inflammation and endothelial dysfunction were associated with greater carotid stiffness in a population-based cohort of elderly individuals. | 22343535 |
| Inflammation | Altered Intercellular Communication | These data suggest that low-grade inflammation, in the elderly, plays an important role in carotid artery remodelling and stiffening. | 22343535 |
| Inflammation, Prostate carcinoma | Altered Intercellular Communication | Systemic inflammation and survival of patients with prostate cancer: evidence from the Glasgow Inflammation Outcome Study. | 22343838 |
| Inflammation, Prostate carcinoma | Altered Intercellular Communication | There is some evidence that systemic inflammation may be associated with survival in patients with prostate cancer; however, it is unclear whether this is independent of grade. | 22343838 |
| Prostate carcinoma | Altered Intercellular Communication | Inflammation-based prognostic scores predict outcome in patients with prostate cancer and should be added to their routine clinical assessment. | 22343838 |
| Malignant mesothelioma, Secondary malignant neoplasm of pleura, Inflammation, Malignant Neoplasms | Altered Intercellular Communication | A definitive diagnosis was obtained in all cases: malignant mesothelioma in 13 cases, other malignancies (pleural metastases) in 8 cases and non-specific inflammation in 3 patients. | 22345186 |
| Inflammation, Asthma | Altered Intercellular Communication | The neutrophilic inflammatory phenotype is associated with systemic inflammation in asthma. | 22345378 |
| Inflammation, Asthma | Altered Intercellular Communication | The role of systemic inflammation in asthma is unclear. | 22345378 |
| Inflammatory, Inflammation, Asthma | Altered Intercellular Communication | The aim of this study was to compare systemic inflammation in subjects with stable asthma, categorized by airway inflammatory phenotype, with healthy control subjects. | 22345378 |
| neutrophilic, Asthma, Inflammation | Altered Intercellular Communication | The asthma (neutrophilic) group had increased systemic inflammation compared with the asthma (nonneutrophilic) and healthy control groups, with median (interquartile range) CRP levels of 5.0 (1.6-9.2), 1.8 (0.9-5.3), and 1.8 (0.8-4.1) mg/L (P = .011), respectively, and IL-6 levels of 2.1 (1.5-3.1), 1.4 (1.0-2.1), and 1.1 (0.8-1.5) pg/mL (P < .001), respectively. | 22345378 |
| Airway structure, Inflammation, Asthma | Altered Intercellular Communication | Systemic inflammation is increased in patients with asthma with neutrophilic airway inflammation and associated with worse clinical outcomes. | 22345378 |
| Inflammation | Altered Intercellular Communication | Systemic inflammation may contribute to the pathophysiology of neutrophilic asthma. | 22345378 |
| Inflammation, HIV-1 Infection Pathway, Pneumonia, Interstitial, Cessation of life, Respiratory Failure | Altered Intercellular Communication | Protective role of peroxisome proliferator-activated receptor-g. HIV-1-induced interstitial pneumonitis (IP) is a serious complication of HIV-1 infection, characterized by inflammation and cellular infiltration in lungs, often leading to respiratory failure and death. | 22345580 |
| Inflammation, Lupus Erythematosus, Lupus Erythematosus, Systemic | Altered Intercellular Communication | Ongoing inflammation including activation of the complement system is a hallmark of systemic lupus erythematosus (SLE). | 22345666 |
| Chronic kidney disease stage 5, Kidney Failure, Chronic | Altered Intercellular Communication | In patients with end stage renal disease (ESRD) we observed protection from inflammation-associated mortality in CCR5D32 carriers, leading to CCR5 deficiency, suggesting impact of CCR5D32 on inflammatory processes. | 22348061 |
| Kidney Failure, Chronic | Altered Intercellular Communication | These differences may be involved in the previously observed protection from inflammation-associated mortality in ESRD patients carrying CCR5D32. | 22348061 |
| ARCN1 gene, Lung Diseases, Obstructive, Airway structure | Altered Intercellular Communication | Asthma and COPD are obstructive airway diseases related to chronic airway inflammation. | 22348544 |
| Inflammation | Altered Intercellular Communication | Potential antigens inducing sarcoid inflammation include mycobacterial and auto-antigens. | 22349068 |
| Gingivitis, Periodontal Diseases | Altered Intercellular Communication | Adjunctive use of slow-released chlorhexidine might be considered in the management of periodontal disease and gingival inflammation to reduce the need for periodontal surgery. | 22350036 |
| Inflammation, hepcidin | Altered Intercellular Communication | Surgical inflammation induces hepcidin production after abdominal surgery. | 22350482 |
| Inflammation, hepcidin | Altered Intercellular Communication | Hepcidin, a key regulator of iron homeostasis, is also a marker of acute inflammation. | 22350482 |
| Airway structure, ARCN1 gene | Altered Intercellular Communication | Alveolar nitric oxide (CA(NO)) has been suggested as a surrogate marker of distal airway inflammation in COPD. | 22350679 |
| Granulomatous inflammation, Necrosis | Altered Intercellular Communication | The cytology patterns observed included granulomatous inflammation and necrosis with or without acid fast bacilli. | 22351190 |
| Inflammation, Nutritional anemia, Anemia, Cessation of life, Chronic Kidney Diseases | Altered Intercellular Communication | Of those with anemia (n = 862, deaths = 491), 24% had nutritional anemia, 11% had anemia of chronic renal disease, 26% had anemia of chronic inflammation, and 39% had unexplained anemia. | 22351246 |
| Inflammation, Anemia, Chronic Kidney Diseases | Altered Intercellular Communication | Compared to persons without anemia, we found the following RRs for the type of anemia: nutritional (2.34, p < 0.0001), chronic renal disease (1.70, p < 0.0001), chronic inflammation (1.48, p < 0.0001), and unexplained (1.26, p < 0.01). | 22351246 |
| Systemic disease | Altered Intercellular Communication | There have been many causes identified ranging from chronic aging joint changes to inflammatory conditions or systemic disorders. | 22351538 |
| Inflammatory abnormality of the eye, Candidiasis, Chronic Mucocutaneous, Stenosis of nasolacrimal duct | Altered Intercellular Communication | Given the strong association between erosive mucocutaneous LP and multisite scarring sequelae, it is not unexpected that ocular inflammation may lead to lacrimal duct stenosis. | 22351823 |
| Inflammation | Altered Intercellular Communication | The histological findings revealed chronic inflammation of the pleura on a hematoxylin-eosin (HE) stain, but treatment with an increased dose of corticosteroid did not improve his effusion. | 22352049 |
| Metabolic Diseases, Amenorrhea, Chromosome Aberrations, Hormone abnormality, teratologic, Gonadal Dysgenesis, Vulva | Altered Intercellular Communication | In general, primary amenorrhea is caused by gonadal dysgenesis, anomalies of internal or external genitalia with or without chromosomal anomalies, and sometimes by hormonal abnormalities that affect the hypothalamus, pituitary, ovaries, adrenals or thyroid, or by chronic or metabolic diseases. | 22353374 |
| Inflammation | Altered Intercellular Communication | Systemic inflammation is associated with vessel wall damage, upregulation of procoagulants, downregulation of anticoagulants, and suppression of fibrinolysis. | 22353382 |
| Inflammation | Altered Intercellular Communication | The activity and chronic inflammation scores were significantly decreased in regression group. | 22353533 |
| Inflammation | Altered Intercellular Communication | In non-regression group, there was no significant difference in activity scores, but the chronic inflammation score was significantly increased. | 22353533 |
| Inflammation, Diabetes Mellitus | Altered Intercellular Communication | A 59-year-old man with a long history of under-treated diabetes mellitus presented with severe inflammation that had spread from the sinus to the left orbital cavity. | 22354231 |
| Sinusitis, Communicable Diseases, Inflammation | Altered Intercellular Communication | Based on the presence of central nervous system (CNS) inflammation and vascular involvements that spread from the sinusitis, we tentatively diagnosed this patient as having invasive fungal CNS infection, i.e. | 22354231 |
| Necrotizing granulomatous inflammation, Coagulative necrosis | Altered Intercellular Communication | Microscopically, the mass was composed of chronic granulomatous inflammation with extensive coagulation necrosis and parasite-like structure, which was revealed as parasitic vesicles and laminated layer delineated by periodic acid-Schiff (PAS) stain. | 22355210 |
| Catatonia, Familial episodic pain syndrome | Altered Intercellular Communication | Catatonia is an episodic syndrome characterized by specific affective, behavioral, and motor symptoms and thought to result from regional abnormalities in neurotransmitter function. | 22356926 |
| Arterial Stiffness, Diabetes Mellitus, Insulin-Dependent, Inflammation, Cardiovascular Diseases | Altered Intercellular Communication | Arterial stiffness is increased in patients with type 1 diabetes without cardiovascular disease: a potential role of low-grade inflammation. | 22357186 |
| Arterial Stiffness, Inflammation, Diabetes Mellitus, Insulin-Dependent, Cardiovascular Diseases | Altered Intercellular Communication | To investigate the relationship between arterial stiffness and low-grade inflammation in subjects with type 1 diabetes without clinical cardiovascular disease. | 22357186 |
| Inflammation, Diabetes Mellitus | Altered Intercellular Communication | In men, multiple linear regression analysis showed that the following variables were associated independently with aPWV: age, BMI, type 1 diabetes, and low-grade inflammation (R(2) = 0.543). | 22357186 |
| Arterial Stiffness, Diabetes Mellitus, Insulin-Dependent, Inflammation | Altered Intercellular Communication | In men with type 1 diabetes, low-grade inflammation is independently associated with arterial stiffness. | 22357186 |
| Inflammation, ETV3 wt Allele | Altered Intercellular Communication | While MetS is a proinflammatory state, there is a paucity of data on cellular inflammation in MetS. | 22357188 |
| Inflammation, Chronic heart failure, Congestive heart failure | Altered Intercellular Communication | Low-grade inflammation seems to play a crucial role in development and progression of chronic heart failure (CHF). | 22357441 |
| methyldopa, Inflammation | Altered Intercellular Communication | Although pathogenic factors, such as oxidative stress, inflammation and genetics are thought to contribute to the development of AMD, little is known about the relationships and priorities between these factors. | 22357958 |
| Inflammation | Altered Intercellular Communication | Therefore, we propose a consecutive pathogenic pathway involving photic stress, oxidation of phospholipids and chronic inflammation, leading to angiogenesis. | 22357958 |
| methyldopa, Inflammation | Altered Intercellular Communication | These findings add to the current understanding of AMD pathology and suggest protection from oxidative stress or suppression of the subsequent inflammation as new potential therapeutic targets for AMD. | 22357958 |
| palladium, Inflammation, Anemia | Altered Intercellular Communication | Lower HMA level, which might be caused by chronic inflammation, anemia and accumulation of dialyzable uremic toxin(s), is closely related to serious CVD incidence among PD patients. | 22358613 |
| Inflammation, Non-alcoholic Fatty Liver Disease | Altered Intercellular Communication | In addition, patients with NAFLD had significantly decreased circulating EPC levels (all P<0.05), attenuated EPC functions, and enhanced systemic inflammation compared to controls. | 22359630 |
| Inflammatory Bowel Diseases, Inflammation, Primary malignant neoplasm, Communicable Diseases, Crohn Disease, Reactive systemic amyloidosis | Altered Intercellular Communication | Secondary amyloidosis (AA) is a rare but serious complication that occurs in the context of cancer, chronic inflammation and chronic infectious diseases, including inflammatory bowel disease, mainly long-standing Crohn's disease. | 22359896 |
| ARCN1 gene, Inflammation, Osteoporosis | Altered Intercellular Communication | COPD patients have many risk factors for osteoporosis, such as low BMI, decreased activity, systemic inflammation, and use of corticosteroids. | 22360380 |
| Seizures, Cessation of life, Synaptic cleft, Respiratory arrest | Altered Intercellular Communication | The irreversible inhibition of AChE causes the neurotransmitter to accumulate in the synaptic cleft, leading to overstimulation of cholinergic receptors, seizures, respiratory arrest, and death. | 22360473 |
| Inflammation, Calcinosis | Altered Intercellular Communication | Reoperation is associated with increased morbidity and is not always successful because of underlying tissue friability, inflammation, or calcification. | 22361595 |
| Pleural Effusion, CTCAE, Inflammation, Fever, CTCAE | Altered Intercellular Communication | Thus, in patients with prolonged fever and systemic symptoms, a 'bland' left-sided pleural effusion may be a diagnostic clue to underlying inflammation of large thoracic arteries. | 22362125 |
| ARCN1 gene, Chronic Obstructive Airway Disease, Pneumonitis | Altered Intercellular Communication | Chronic obstructive pulmonary disease (COPD) is characterized by the abnormal and chronic lung inflammation. | 22363103 |
| ARCN1 gene, Inflammation | Altered Intercellular Communication | Our data suggest that lung fibroblasts participate in the chronic inflammation in COPD by releasing IL-6 and IL-8, and low dose theophylline can alleviate the proinflammatory mediators' production by fibroblasts. | 22363103 |
| Inflammation, Stiff toe, Diabetes Mellitus, Non-Insulin-Dependent | Altered Intercellular Communication | Pedometer-determined physical activity is linked to low systemic inflammation and low arterial stiffness in Type 2 diabetes. | 22364114 |
| Inflammation, Stiff toe, Obesity, Abdominal, Diabetes Mellitus, Non-Insulin-Dependent | Altered Intercellular Communication | We conclude that physical activity measured with pedometer was associated not only with less abdominal obesity, but also with decreased systemic low-grade inflammation as well as with low arterial stiffness, in people with Type 2 diabetes. | 22364114 |
| Inflammation, Renal calcium wasting, Zinc deficiency | Altered Intercellular Communication | Further studies should clarify whether inflammation related processes such as renal wasting contribute to zinc deficiency and underlie the adverse health consequences of low serum zinc levels. | 22365070 |
| Coinfection, Inflammation, Lyme Disease, Hepatitis | Altered Intercellular Communication | Although hepatitis complicating the course of Lyme disease has been described in literature, the marked inflammation in our patient led us to investigate the possibility of a co-infection. | 22365471 |
| Headache | Altered Intercellular Communication | The significant decrease in headache prevalence observed during pregnancy may be the result of a pregnancy-specific hormonal status. | 22365591 |
| Inflammation, Fracture | Altered Intercellular Communication | Chronic inflammation impairs recovery among the 1.6 million people who suffer from hip fracture annually. | 22365613 |
| Inflammation | Altered Intercellular Communication | The association weakened but remained statistically significant after additional adjustment for systemic markers of inflammation. | 22366234 |
| Hashimoto Disease, Chronic inflammation, Endothelial dysfunction, Haiti | Altered Intercellular Communication | The etiopathogenesis of Hashimoto's thyroiditis (HT) has not been clearly elucidated although the role of chronical inflammation and endothelial dysfunction has been established. | 22366404 |
| Inflammation, Traumatic | Altered Intercellular Communication | Lifetime exposure to traumatic psychological stress is associated with elevated inflammation in the Heart and Soul Study. | 22366689 |
| Inflammation | Altered Intercellular Communication | While the biological mechanisms of these effects are not known, inflammation may play a key role as it is both elevated by psychological stress and involved in the development and progression of CVD. | 22366689 |
| Inflammation, Traumatic injury | Altered Intercellular Communication | In a prospective study of patients with stable CVD (n=979), we examined if higher lifetime trauma exposure was associated with elevated levels of inflammation at baseline and at five-year follow-up, and with greater increases in inflammation over time. | 22366689 |
| Inflammation, Tumor necrosis | Altered Intercellular Communication | Inflammation was indexed by a composite score incorporating the inflammatory markers interleukin-6 (IL-6), tumor necrosis factor-a (TNF-a), C-reactive protein (CRP) and resistin. | 22366689 |
| Inflammation, Traumatic injury | Altered Intercellular Communication | Higher trauma exposure was associated with elevated inflammation at baseline (b=.09, p=.01) and at five-year follow-up (b=.09, p=.03). | 22366689 |
| Inflammation, Traumatic injury | Altered Intercellular Communication | While levels of inflammation increased from baseline to follow-up in the sample, there was no significant association between trauma exposure and rate of change in inflammation. | 22366689 |
| Inflammation, Mental disorders, Traumatic injury | Altered Intercellular Communication | Findings were robust to adjustments for sociodemographic factors and psychiatric disorders, but health behaviors appeared to contribute to the association between trauma and inflammation at follow-up. | 22366689 |
| Inflammation, Traumatic injury | Altered Intercellular Communication | This is the first large-scale demonstration of an association between lifetime trauma exposure and inflammation. | 22366689 |
| Inflammation, Traumatic | Altered Intercellular Communication | High lifetime exposure to traumatic stress may contribute to an accelerated rate of CVD progression through elevated inflammation. | 22366689 |
| Tissue injury, MS gene | Altered Intercellular Communication | Our data suggest that the inflammation-associated oxidative burst in activated microglia and macrophages plays an important role in demyelination and free radical-mediated tissue injury in the pathogenesis of multiple sclerosis. | 22366799 |
| Inflammation, Abnormal degeneration, Elastosis perforans serpiginosa | Altered Intercellular Communication | Processes associated with tissue degeneration but not with inflammation are highly prevalent among subjects with EPS. | 22367046 |
| Carcinogenic Chlorinated Hydrocarbon, Inflammation | Altered Intercellular Communication | CHC patients, irrespective of liver function, had higher frequencies of Tregs than healthy subjects; however, only CHC patients with inflammation showed enhanced immunosuppressive function of Tregs. | 22367277 |
| Inflammation | Altered Intercellular Communication | Associations of inflammation with age-related pathologies are documented; however, it is not understood how changes in inflammation over time impact healthy aging. | 22367431 |
| Inflammation, BDI - Functional Impairment | Altered Intercellular Communication | Although increases in inflammation markers over 9 years were associated with higher concurrent risk of functional impairment and subsequent CVD events and mortality, final levels of each biomarker appeared to be more important in determining risk of subsequent events than change over time. | 22367431 |
| Inflammation | Altered Intercellular Communication | We previously demonstrated that NF-kB, a transcription factor traditionally associated with inflammation, plays a unique protective role in the neonatal lung. | 22367785 |
| Psychotic Disorders, Impaired cognition, Inflammation, Schizophrenia | Altered Intercellular Communication | Severe psychosis and mild cognitive decline without other neurological features, meeting the Diagnostic and Statistical Manual of Mental Disorders, 4th edition, text revision diagnostic criteria for schizophrenia, can result from brain inflammation associated with elevated serum anti-GADAbs. | 22367838 |
| Airway structure | Altered Intercellular Communication | Polymorphisms in nitric oxide synthase genes (NOS1, NOS2, and NOS3) have been suggested to have a major impact on fraction of exhaled nitric oxide (FENO), a biomarker of airway inflammation. | 22368302 |
| Familial spinal arachnoiditis, Inflammation | Altered Intercellular Communication | Spinal arachnoiditis describes inflammation of the meninges, subarachnoid space and, in most cases, also involve the pial layer. | 22369357 |
| Pregnancy loss, Amenorrhea | Altered Intercellular Communication | A novel luteinizing hormone/chorionic gonadotropin receptor mutation associated with amenorrhea, low oocyte yield, and recurrent pregnancy loss. | 22369774 |
| Communicable Diseases, Primary malignant neoplasm, Fever of Unknown Origin, Vasculitis, CTCAE | Altered Intercellular Communication | The causes of FUO in the other PET positive patients were: infection (n = 3), vasculitis (n = 3), non-infectious inflammatory conditions (n = 2) and cancer (n = 1). | 22369860 |
| Vasculitis, Leukocytoclastic, Cutaneous, Inflammation, Exanthema | Altered Intercellular Communication | Histological examination showed dermal-ipodermal inflammation with evidence of leukocytoclastic vasculitis principally interesting the small venules The cutaneous rash resolved after 2 weeks. | 22370576 |
| Inflammatory Bowel Diseases, Inflammation | Altered Intercellular Communication | All IBD and non-IBD patients who had a FC measurement available before full endoscopic evaluation for suspected bowel inflammation were examined. | 22370604 |
| ACSM3 gene, Inflammation, Subarachnoid Hemorrhage, Aneurysmal, Vasospasm | Altered Intercellular Communication | Vasospasm is a major contributor to morbidity and mortality in aneurysmal subarachnoid hemorrhage (SAH), with inflammation playing a key role in its pathophysiology. | 22370810 |
| Inflammation, Gallbladder Biliary Intraepithelial Neoplasia, Fibrosis Assessment | Altered Intercellular Communication | Inflammation and fibrosis of the gallbladder wall were more common in tissue with gallbladder dysplasia/carcinoma than in benign tissue 12/25 (48%) versus 4/28 (12%) (p < 0.01) and in 13/21 (62%) versus 3/32 (9%) (p < 0.0001), respectively. | 22370917 |
| Lesion, Inflammation | Altered Intercellular Communication | Caries lesions on abutment teeth were seen in 31.6% of patients, and 35.6% showed inflammation of the periodontal tissue surrounding the abutment teeth. | 22371834 |
| Rheumatoid Arthritis, BDI - Functional Impairment, Swelling, Inflammatory disorder, Arthritis | Altered Intercellular Communication | Rheumatoid Arthritis is a chronic inflammatory disease resulting in joint inflammation (particularly joints of hands, wrists, feet, knees, ankles, and shoulder) that is manifested by swelling and functional impairment. | 22372341 |
| Inflammation, Fibrosis Assessment, Fatty degeneration | Altered Intercellular Communication | There was no clear-cut correlation between the pattern of alanine aminotransferase levels and changes in steatosis, inflammation, hepatocyte ballooning, or fibrosis stage over time. | 22373863 |
| Inflammation, Vascular Diseases | Altered Intercellular Communication | Blood vessels and soft tissues are injured by inflammation as the primary target of collagen vascular diseases. | 22373989 |
| Autoimmune Diseases, Inflammation, mitomycin | Altered Intercellular Communication | Inflammation due to autoimmune disease is believed to play an important role in the formation of MTC. | 22374595 |
| Inflammation, Stomach Carcinoma | Altered Intercellular Communication | One of the mechanisms proposed by which H. pylori causes gastric cancer (GC) is through DNA damage due to chronic inflammation. | 22374853 |
| Inflammation, Pain, Postoperative | Altered Intercellular Communication | HA-CMC can decrease immediate postoperative pain arising from tissue adhesion and inflammation, thus reducing postoperative mastication pain. | 22377324 |
| Inflammation, Renal carcinoma | Altered Intercellular Communication | Prospective study of the role of inflammation in renal cancer. | 22377628 |
| Airway structure | Altered Intercellular Communication | Subclinical changes in airway inflammation can be measured by fractional exhaled nitric oxide (FeNO). | 22377682 |
| Inflammation, Obesity | Altered Intercellular Communication | Adiposity, traditional food intake, long-chain RBC PUFA status, and inflammation were positively associated with SF and food insecurity, smoking, and H. pylori seropositivity were negatively associated with SF. | 22378332 |
| Inflammation, Heart failure | Altered Intercellular Communication | Adipose tissue inflammation and adiponectin resistance in patients with advanced heart failure: correction after ventricular assist device implantation. | 22379072 |
| Inflammation, Heart failure | Altered Intercellular Communication | Heart failure (HF) is characterized by inflammation, insulin resistance, and progressive catabolism. | 22379072 |
| Degenerative polyarthritis, Inflammation, Osteoporosis | Altered Intercellular Communication | Recent evidence suggests that inflammation may play a role in osteoporosis (OP) and osteoarthritis (OA). | 22380539 |
| Nightmares, Migraine Disorders, Hay fever, Motion Sickness, Asthma, Epilepsy | Altered Intercellular Communication | Adolescent migraine is associated with inflammatory conditions such as asthma and seasonal allergies, as well as with epilepsy, persistent nightmares, and motion sickness. | 22381023 |
| Pneumonitis | Altered Intercellular Communication | Pulmonary inflammation is a substantive prognostic factor for Ivor Lewis operations. | 22381051 |
| Rheumatoid Arthritis, Temporomandibular Joint | Altered Intercellular Communication | Rheumatoid arthritis is a chronic inflammatory condition that can result in progressive destruction of the articular surfaces of the joints, including the temporomandibular joint. | 22381496 |
| Inflammation, Chronic disease, Atherosclerosis | Altered Intercellular Communication | Atherosclerosis is a progressive chronic disease, in which inflammation plays a key role. | 22382154 |
| Inflammation, Cerebrovascular accident | Altered Intercellular Communication | The positive associations between D-dimer and vWF and incident stroke remained after additional adjustment for markers of inflammation (C-reactive protein, IL-6). | 22382157 |
| Orbital Pseudotumor | Altered Intercellular Communication | There are very few reports of WG with orbital inflammation and exorbitism. | 22382229 |
| Orbital Pseudotumor | Altered Intercellular Communication | We report a case of a female patient who presented with exorbitism related to orbital inflammation secondary to WG, with renal involvement. | 22382229 |
| Communicable Diseases, Inflammation | Altered Intercellular Communication | Chronic inflammation is correlated with percentage of body fat independent of the burden of infection. | 22382515 |
| Inflammation, Ruptured simple cyst | Altered Intercellular Communication | Histopathologic findings of the excised mass were consistent with an epidermal inclusion cyst with surrounding moderate chronic inflammation and cyst rupture. | 22382849 |
| Inflammation, Stomach Carcinoma, Hyperplasia | Altered Intercellular Communication | Development of gastric cancer in nonatrophic stomach with highly active inflammation identified by serum levels of pepsinogen and Helicobacter pylori antibody together with endoscopic rugal hyperplastic gastritis. | 22383377 |
| Inflammation, Primary malignant neoplasm | Altered Intercellular Communication | Meanwhile, endoscopic findings revealed that 11.7% of subjects showed RHG reflecting localized highly active inflammation, and cancer risk was significantly higher in patients with RHG than in patients without. | 22383377 |
| Chronic Kidney Diseases | Altered Intercellular Communication | At baseline, compared with controls, fasting CKD subjects had higher parathyroid hormone and fibroblast growth factor 23 levels and greater fractional excretion of phosphate. | 22383746 |
| Inflammation, Malignant Female Reproductive System Neoplasm | Altered Intercellular Communication | [Changes in calprotectin concentration--inflammation marker in serum of women with gynecological cancer]. | 22384614 |
| Inflammation, Neoplasms | Altered Intercellular Communication | There is a relation between an impaired immune system, especially the process of inflammation and the pathogenesis of these tumors. | 22384614 |
| Inflammation, Peripheral Nervous System | Altered Intercellular Communication | Although MS is mostly a multifocal chronic inflammation of the central nervous system, peripheral nervous system can also be involved. | 22384779 |
| Inflammation, Sensorineural Hearing Loss (disorder) | Altered Intercellular Communication | Although the etiology of idiopathic sudden sensorineural hearing loss (SSNHL) remains unclear, the pathologically increased permeability of blood vessels, elucidated by gadolinium-enhanced magnetic resonance imaging (MRI), suggests the involvement of inflammation. | 22385075 |
| Inflammation, Sensorineural Hearing Loss (disorder) | Altered Intercellular Communication | Because permeability of blood vessels in the inner ear is frequently increased in patients with SSNHL, inflammation of the inner ear might be involved. | 22385075 |
| fluorouracil/mitomycin/streptozocin, Inflammation, Fibrosis Assessment | Altered Intercellular Communication | Oral submucous fibrosis (OSMF) is associated with paan chewing, altered collagen metabolism, inflammation and the upregulation of numerous cytokines. | 22385081 |
| vascular inflammations, Endothelial dysfunction, Atherosclerosis | Altered Intercellular Communication | Oxidative stress results from an imbalance of prooxidants and antioxidants and leads to endothelial dysfunction that promotes vascular inflammation and atherosclerosis. | 22385338 |
| Inflammation, Fatty degeneration, Hepatitis C | Altered Intercellular Communication | HCV infection is a risk factor for earlier and facilitated occurrence of CA via viral load and steatosis which modulate atherogenic factors such as inflammation and dysmetabolic milieu. | 22385985 |
| Inflammation, Glaucoma, CTCAE | Altered Intercellular Communication | Postoperative inflammation (48% vs 16%) and glaucoma (40% vs 16%) were seen more frequently in eyes with sutures as compared to eyes with glue. | 22386370 |
| Malignant neoplasm of urinary bladder, Inflammation | Altered Intercellular Communication | Influence of urinary tract instrumentation and inflammation on the performance of urine markers for the detection of bladder cancer. | 22386412 |
| Inflammation, Hematuria, CTCAE | Altered Intercellular Communication | To evaluate the impact of inflammation and sampling on cytology, immunocytology, and fluorescence in situ hybridization (FISH) in comparison with NMP22 in hematuria patients. | 22386412 |
| Inflammation | Altered Intercellular Communication | False-positive results were compared with regard to the presence or absence of inflammation and mechanical manipulation. | 22386412 |
| Inflammation | Altered Intercellular Communication | Inflammation led to a rise in false-positive NMP22 test results (85.3% vs 61.4%, P < .0001). | 22386412 |
| Inflammation, ETV3 wt Allele | Altered Intercellular Communication | Importantly, we showed that this association was independent of potential confounders, especially all of the MetS components and inflammation. | 22386703 |
| Primary malignant neoplasm | Altered Intercellular Communication | Therefore, this observation suggests that genetic variation in inflammation-related genes could be an important mediator of the complex interplay between ageing and cancer. | 22387051 |
| Inflammation, Autoimmune Atrophic Chronic Gastritis, Achlorhydria, Immune-mediated | Altered Intercellular Communication | Autoimmune atrophic gastritis (AIG) is characterized by immune-mediated chronic inflammation of the gastric body and fundus, leading to hypo-achlorhydria and vitamin B12 deficiency. | 22387252 |
| Peritonitis | Altered Intercellular Communication | Neutrophilic inflammation in experimental peritonitis in mice decreased iNKT cell T-box transcription factor 21 and GATA3 expression and a-galactosyl ceramide-induced cytokine production in vivo. | 22387552 |
| Inflammation | Altered Intercellular Communication | Our data reveal a novel regulatory axis whereby neutrophils reduce iNKT cell responses, which may be important in shaping the extent of inflammation. | 22387552 |
| Inflammation, exacerbation acute | Altered Intercellular Communication | One factor implicated in this process is systemic inflammation, an accompaniment of acute exacerbations. | 22388793 |
| Arthritis | Altered Intercellular Communication | Inflammation assessment in patients with arthritis using a novel in vivo fluorescence optical imaging technology. | 22388997 |
| Inflammation | Altered Intercellular Communication | Indocyanine green (ICG)-enhanced fluorescence optical imaging (FOI) is an established technology for imaging of inflammation in animal models. | 22388997 |
| Refractory anemias, Rheumatoid Arthritis, Inflammation, Cardiovascular morbidity | Altered Intercellular Communication | Rheumatoid arthritis (RA) is associated with increased cardiovascular morbidity and mortality attributed to both classical risk factors and chronic inflammation. | 22390577 |
| Vasculitis | Altered Intercellular Communication | In late biopsies, high NK-cell transcript expression was associated with antibody-mediated rejection, correlating with microvascular inflammation and donor specific HLA antibody. | 22390872 |
| Tubulitis Assessment, Interstitial inflammation | Altered Intercellular Communication | However, some early biopsies with T cell-mediated rejection had high NK-cell transcript expression, as well as T cell transcripts, without evidence of antibody-mediated rejection or DSA, correlating with interstitial inflammation and tubulitis. | 22390872 |
| Inflammation, Atrophic, Natural Killer Cells | Altered Intercellular Communication | Both NK-cell and T cell transcripts were moderately increased in many kidneys with inflammation secondary to injury or atrophy scarring. | 22390872 |
| Inflammation, Atrophic | Altered Intercellular Communication | These results support the distinct role of NK cells in late antibody-mediated rejection, but indicate a role for NK-transcript expressing cells (NK cells or T cells with NK features) both in T cell-mediated rejection and in inflammation associated with injury and atrophy scarring. | 22390872 |
| Inflammation, Obesity, Abdominal | Altered Intercellular Communication | Overexpression of S100A8 and S100A9 in obese adipose tissue may be involved, at least partly, in not only high circulating levels of S100A8/A9 complex in abdominal obesity but also adipose and systemic tissue inflammation. | 22390934 |
| Inflammation, Necrosis | Altered Intercellular Communication | Muscle biopsy showed necrosis, inflammation, and positive HLA class I immunostaining. | 22391471 |
| Inflammation, Depression, CTCAE, Metabolic Syndrome X | Altered Intercellular Communication | Increased inflammation and lower platelet 5-HT in depression with metabolic syndrome. | 22391518 |
| Disease | Altered Intercellular Communication | For both disorders, impaired serotoninergic neurotransmission and inflammatory factors have been suggested. | 22391518 |
| Acute inflammation of orbit | Altered Intercellular Communication | This study reports 3 cases of acute orbital inflammation that occurred within 3 weeks of various dental procedures and offers a possible mechanism as to their cause. | 22391741 |
| Inflammation | Altered Intercellular Communication | The last individual had recurrent symptoms prompting lacrimal gland biopsy that demonstrated chronic, nongranulomatous inflammation without monoclonality. | 22391741 |
| Acute inflammation of orbit | Altered Intercellular Communication | The authors propose that a subset of acute orbital inflammation may represent an autoimmune response triggered by dental manipulation. | 22391741 |
| Communicable Diseases, Inflammation | Altered Intercellular Communication | These cases are suggestive of an atypical variant of noninfectious, microbe-induced inflammation. | 22391741 |
| Refractory anemias, Inflammation, Rheumatoid Arthritis, Peripheral | Altered Intercellular Communication | Chronic inflammation of the peripheral joints is a hallmark of rheumatoid arthritis (RA). | 22391806 |
| Inflammation, Microvascular Angina, Obesity | Altered Intercellular Communication | Obesity, inflammation and brachial artery flow-mediated dilatation: therapeutic targets in patients with microvascular angina (cardiac syndrome X). | 22392186 |
| Inflammation, physiopathological, Obesity | Altered Intercellular Communication | The results support the concept that low-grade inflammation and obesity may promote vascular dysfunction in these patients representing therapeutic targets for future research investigations. | 22392186 |
| Inflammation, Lupus Erythematosus, Systemic, Autoimmune Diseases, Acute and chronic inflammation, Lupus Erythematosus | Altered Intercellular Communication | Systemic lupus erythematosus (SLE) is an autoimmune disease with chronic or episodic inflammation in several organ systems, related to the presence of circulating and tissue-deposited immune complexes (ICs) that stimulate leukocytes through Fcg receptors (FcgR) with subsequent inflammation. | 22392566 |
| Inflammation, Retinitis Pigmentosa, polychondritis, Autoimmune Disorder, CTCAE | Altered Intercellular Communication | Relapsing polychondritis (RP) is a rare, generalized autoimmune disorder that is characterized by recurrent inflammation of various cartilaginous structures. | 22392754 |
| Inflammation | Altered Intercellular Communication | Pathological findings revealed chronic inflammation of the meninges, so prednisone was administered. | 22392754 |
| Inflammation, Neoplasms | Altered Intercellular Communication | In contrast to intestinal IFP, gastric tumours occur at higher age, show heavy inflammation and tend to be smaller. | 22394371 |
| Inflammation, Malignant Neoplasms | Altered Intercellular Communication | Biopsies showed denuded urothelium and inflammation of the submucosa without malignancy. | 22394445 |
| glycation, Inflammation | Altered Intercellular Communication | EN-RAGE is extracellular newly identified receptor for advanced glycation end-products binding protein playing a role in inflammation. | 22394461 |
| Atherosclerosis | Altered Intercellular Communication | Inflammation of the vascular wall is an essential event in the development of atherosclerosis, the main leukocytes of the inflammatory infiltrate being the monocyte/macrophages. | 22395501 |
| Inflammation | Altered Intercellular Communication | Therefore, it is particularly important to investigate the molecules involved in cardiac inflammation. | 22395526 |
| Rosacea | Altered Intercellular Communication | Papulopustular acne rosacea is a chronic inflammatory condition which can be difficult to treat. | 22395584 |
| Inflammation, Behcet Syndrome, irSD (Immune-Related Response Criteria) | Altered Intercellular Communication | Behcet's disease is known as a recurrent, multisystem inflammation and immune-related disease. | 22396730 |
| Inflammatory Bowel Diseases, Inflammation, Fracture, Ileum Perforation, CTCAE_3 | Altered Intercellular Communication | He underwent abdominal CT, which revealed pelvis fractures, abnormal bowel wall of the terminal ileum (wall thickening and mucosal enhancement), peritoneal effusion within the pelvis, mesenteric nodes and extra-luminal gas within an area of mesenteric inflammation: these features were suggestive of ileum perforation associated with inflammatory bowel disease, most likely CD. | 22398044 |
| Granuloma, Inflammation, Specimen Type - Fistula, Fibrosis Assessment, Ileitis, Ulcer | Altered Intercellular Communication | Histological analysis revealed terminal ileitis with ulcers, non caseating granulomas and submucosal fibrosis, a transparietal fistula and a caecoappendicular inflammation, confirming CD. | 22398044 |
| Inflammatory Bowel Diseases, Gastrointestinal inflammation | Altered Intercellular Communication | This study suggests a potential role for Substance P serum levels in monitoring intestinal inflammation in patients with inflammatory bowel disease. | 22398048 |
| Inflammation | Altered Intercellular Communication | Inflammation was graded by endoscopic, clinical, histological and biochemical scoring. | 22398079 |
| Inflammation, Chronic Kidney Diseases | Altered Intercellular Communication | However, our results demonstrate a significant association between TNF-a and renal function, suggesting a potential link between inflammation and the development of CKD. | 22398717 |
| Inflammation | Altered Intercellular Communication | These data also confirm the association between MAU and inflammation. | 22398717 |
| Inflammation, Neoplasms, Primary central nervous system lymphoma, Glioblastoma Multiforme Pathway, Cerebrovascular Disorders | Altered Intercellular Communication | There were 13 patients with PCNSL and 24 patients with other diseases such as glioma, metastatic tumor, inflammation, or cerebrovascular disease. | 22399193 |
| vascular inflammations, diabetic | Altered Intercellular Communication | Genistein prevents hyperglycemia-induced monocyte adhesion to human aortic endothelial cells through preservation of the cAMP signaling pathway and ameliorates vascular inflammation in obese diabetic mice. | 22399524 |
| vascular inflammations, Atherosclerosis, Diabetes Mellitus | Altered Intercellular Communication | Hyperglycemia-induced vascular inflammation resulting in the enhanced monocyte-endothelial cell (EC) interaction is the key event in the pathogenesis of atherosclerosis in diabetes. | 22399524 |
| vascular inflammations | Altered Intercellular Communication | We conclude that genistein improves diabetes-caused vascular inflammation, which may be mediated through promoting the cAMP/PKA pathway. | 22399524 |
| Rheumatoid Arthritis | Altered Intercellular Communication | Gene expression analysis of rheumatoid arthritis synovial lining regions by cDNA microarray combined with laser microdissection: up-regulation of inflammation-associated STAT1, IRF1, CXCL9, CXCL10, and CCL5. | 22401175 |
| Refractory anemias, Rheumatoid Arthritis, Inflammation | Altered Intercellular Communication | The main histological change in rheumatoid arthritis (RA) is the villous proliferation of synovial lining cells, an important source of cytokines and chemokines, which are associated with inflammation. | 22401175 |
| Kidney Failure, Chronic, Periodontitis | Altered Intercellular Communication | Chronic periodontitis (CP) and end-stage renal disease (ESRD) are complex inflammatory conditions. | 22401717 |
| Tumor necrosis, Inflammation | Altered Intercellular Communication | [Tumor necrosis factor as an early marker of inflammation in healthy smokers]. | 22401725 |
| Degenerative polyarthritis, Inflammation, Erosion lesion, 4-hydroxy-2-oxovalerate aldolase activity | Altered Intercellular Communication | Erosive osteoarthritis of the hand (EHOA) is thought to be an aggressive variant of hand osteoarthritis (HOA) characterised by prominent local inflammation and radiographic aspects of bone erosions in interphalangeal (IP) joints. | 22401873 |
| Chronic infectious disease, Inflammation, Epithelial ovarian cancer | Altered Intercellular Communication | The present study validates the theory of chronic infections and inflammation in the pathogenesis of epithelial ovarian cancer. | 22402815 |
| Inflammation, Dermatitis, Irritant | Altered Intercellular Communication | Genetic variations in genes coding for cytokines involved in skin inflammation may alter their expression, thus changing the susceptibility to irritant contact dermatitis (ICD). | 22404198 |
| Inflammation, Complication Aspects, Atherosclerosis, Communicable Diseases, Hepatitis C | Altered Intercellular Communication | Hepatitis C virus (HCV) infection is associated with systemic inflammation and metabolic complications that might predispose patients to atherosclerosis. | 22404725 |
| Inflammation | Altered Intercellular Communication | The presence of bowel inflammation and fistulas should not preclude such diagnosis. | 22405176 |
| Refractory anemias, Inflammation, Arthritis | Altered Intercellular Communication | In RA patients, chronic inflammation of this tendon or talonavicular joint arthritis can results in posterior tibial tendon rupture. | 22405554 |
| Refractory anemias, Rupture, Fibrinoid necrotizing inflammation | Altered Intercellular Communication | In a 61-year-old RA patient, ruptures of the posterior tibial tendon due to rheumatoid inflammation occurred bilaterally, with subsequent deviation and instability of the forefoot. | 22405554 |
| Neurogenic Inflammation | Altered Intercellular Communication | The aim of this investigation is to determine the correlation between neurogenic inflammation and nociception associated with OLP-R and OLP-E. | 22406713 |
| Inflammation, Leucocytic infiltrate | Altered Intercellular Communication | We found that 1) an increase in peripheral innervation was related to the size of the area of inflammatory cell infiltration from both OLP-R and OLP-E; 2) the pattern of PGP 9.5-immunoreactivity among OLP-R and OLP-E was not significantly different (P=0.23); and 3) the correlation between nociception and an increase in PGP 9.5-immunoreactivity was not found in OLP-E and in OLP-R. Our findings suggest that an increase in peripheral innervation may lead to increased inflammation, which is part of the immunopathogenesis of OLP. | 22406713 |
| Fibrosis Assessment | Altered Intercellular Communication | Hepatic allograft inflammation grade >=2 and fibrosis stage >=2 occurred in 221 (64%) and 140 (40%) patients, respectively. | 22406819 |
| Inflammation, Fibrosis Assessment, Cytomegalovirus | Altered Intercellular Communication | CMV disease was associated with increased risk of inflammation grade >=2 (RR, 3.40; P<0.001), and although not significant, with fibrosis stage >=2 (RR, 2.03; P=0.052). | 22406819 |
| Inflammatory Bowel Diseases, Inflammation | Altered Intercellular Communication | As this classification does not consider segmental inflammation, backwash ileitis, or rectal sparing, an additional subgroup analysis was performed in 80 cases and 80 age- and sex-matched IBD controls, reviewing all endoscopy and pathology reports filed between 2000 and 2010. | 22407885 |
| Inflammation, Papilledema, Scotoma | Altered Intercellular Communication | Among the eyes with disc swelling, 13 eyes of 7 patients had visual field defects even after the inflammation subsided, and these patients were older, had a higher DM/DD ratio, and had a smaller C/D ratio than those without visual field defects. | 22408010 |
| Uveomeningoencephalitic Syndrome, Inflammation, Papilledema | Altered Intercellular Communication | The occurrence of disc swelling in VKH was significantly correlated with age and disc morphology, rather than the severity of inflammation. | 22408010 |
| ARCN1 gene, Inflammation, Muscular Atrophy | Altered Intercellular Communication | Oxidation levels of proteins, myosin heavy chain (MyHC) and myonuclei, superoxide anion, antioxidants, actin, creatine kinase, carbonic anhydrase-3, ubiquitin-proteasome system, redox-signalling pathways, inflammation and muscle structure, and damage were quantified in limb muscles of severe COPD patients with and without muscle wasting, and in sedentary controls. | 22408199 |
| Myositis | Altered Intercellular Communication | Muscle inflammation and glutathione levels did not differ between patients and controls. | 22408199 |
| Inflammation, Drug abuse, septic, Diabetes Mellitus | Altered Intercellular Communication | The source of the inflammation was septic lesions of the lower body, whereas the perdisposal factors were considered to be the diabetes mellitus, drug abuse and immunodeficiency. | 22408805 |
| Inflammation, Diabetes Mellitus | Altered Intercellular Communication | The associations between inflammation, diabetes and insulin resistance remain controversial. | 22409372 |
| Inflammation, Vasculitis, CTCAE, Papilledema | Altered Intercellular Communication | When inflammation is present, it can be severe and frequently associated with other complications such vasculitis and papillitis. | 22409567 |
| Inflammation, Autoimmune Chronic Hepatitis, Insemination, Artificial, Homologous | Altered Intercellular Communication | To observe the expression change of signal regulatory protein alpha1 (SIRPalpha1) in autoimmune hepatitis (AIH) and approach the relationship between SIRPalpha1 and the extent of inflammation. | 22409853 |
| Inflammation, Ankylosis | Altered Intercellular Communication | Inhibition of inflammation but not ankylosis by glucocorticoids in mice: further evidence for the entheseal stress hypothesis. | 22410100 |
| Inflammation, Ankylosis, Spondylitis | Altered Intercellular Communication | Studies in the spontaneous ankylosis model in aging male DBA/1 mice and in patients with ankylosing spondylitis provide evidence that inflammation and new tissue formation leading to joint or spine ankylosis are likely linked but largely uncoupled processes. | 22410100 |
| Inflammation, Arthritis, Ankylosis | Altered Intercellular Communication | Here, we further investigated the relationship between inflammation and ankylosis by focusing on the early phase of the spontaneous arthritis model. | 22410100 |
| Inflammation, Ankylosis | Altered Intercellular Communication | Dexamethasone treatment did not affect incidence or severity of ankylosis, but led to an expected reduction in inflammation in the paws at week 15 as measured by PET tracer uptake. | 22410100 |
| Inflammation, Enthesitis, Ankylosis | Altered Intercellular Communication | BMP signaling may be a trigger for both inflammation and ankylosis in the spontaneous model of ankylosing enthesitis. | 22410100 |
| Inflammation, CNDP2 gene, Nerve Degeneration | Altered Intercellular Communication | Altogether, our findings support a key role of CNDP2 in PD neurodegeneration, by mechanisms that could involve oxidative stress, protein aggregation or inflammation. | 22410244 |
| Retinal Vasculitis | Altered Intercellular Communication | This case highlights the importance of considering connective tissue inflammatory conditions in any retinal vasculitis. | 22410282 |
| ARCN1 gene, Inflammation, Chronic Obstructive Airway Disease, Metabolic Syndrome X | Altered Intercellular Communication | Systemic inflammation has been suggested to be involved in the pathogenesis of chronic obstructive pulmonary disease (COPD) and metabolic syndrome. | 22410468 |
| Inflammation, Dystrophic calcification | Altered Intercellular Communication | Tonsilloliths are rare dystrophic calcification formed as a result of chronic inflammation of the tonsils. | 22410514 |
| Scleritis, Inflammatory disorder | Altered Intercellular Communication | To determine the clinical differences between sclerosing orbital inflammation (SOI) isolated to the orbit and SOI manifesting as part of systemic inflammatory disease. | 22410659 |
| Communicable Diseases, Inflammation, Acute infectious disease | Altered Intercellular Communication | Biomarkers of inflammation, including C-reactive protein (CRP) and a(1) -acid glycoprotein (AGP), have tremendous potential in anthropological, public health, and nutrition research as objective indicators of acute infection; however, their usage is limited by the lack of widely agreed upon, reliable cutpoints to define infection. | 22411080 |
| Carcinogenesis | Altered Intercellular Communication | These findings are consistent with research supporting the infectious/inflammation pathway in prostate carcinogenesis. | 22411189 |
| Inflammation, Breast Carcinoma, Fatigue | Altered Intercellular Communication | Fatigue, inflammation, and o-3 and o-6 fatty acid intake among breast cancer survivors. | 22412148 |
| Inflammation, Primary malignant neoplasm, Fatigue | Altered Intercellular Communication | Evidence suggests that inflammation may drive fatigue in cancer survivors. | 22412148 |
| Inflammation, Fatigue | Altered Intercellular Communication | Research in healthy populations has shown reduced inflammation with higher dietary intake of o-3 polyunsaturated fatty acids (PUFAs), which could potentially reduce fatigue. | 22412148 |
| Inflammation, Fatigue | Altered Intercellular Communication | Results link higher intake of o-3 PUFAs, decreased inflammation, and decreased physical aspects of fatigue. | 22412148 |
| ARCN1 gene, Airway structure | Altered Intercellular Communication | In subjects with COPD, nasal epithelial cells cannot substitute for in vitro bronchial epithelial cells in airway inflammation studies. | 22412951 |
| Exacerbation | Altered Intercellular Communication | Neutrophilic inflammation is prominent, worsened during infective exacerbations and is refractory to glucocorticosteroids (GCs). | 22413009 |
| Infertility, Tumor necrosis, Inflammation | Altered Intercellular Communication | In the testes of both infertile men and in a mouse model of inflammation associated infertility (aromatase-overexpressing transgenic mice), the fibrotic changes and increased numbers of tumour necrosis factor (TNF)-a-producing immune cells were shown to be associated with increased production of DCN. | 22413766 |
| Trismus, Inflammation, Toxic effect | Altered Intercellular Communication | Late toxicity occurred as grade 3 trismus in five and as grade 3 abacterial salivary gland inflammation in one patient, respectively. | 22414284 |
| Intraocular inflammation | Altered Intercellular Communication | Five cases of severe intraocular inflammation after intravitreal bevacizumab were documented. | 22414958 |
| Female Genital Diseases, Inflammation, Endometriosis, Atherosclerosis | Altered Intercellular Communication | Endometriosis, a chronic benign gynecological disorder, shows some characteristics, such as oxidative stress, systemic inflammation and a pro-atherogenic lipid profile, which could increase the risk of developing accelerated atherosclerosis. | 22416009 |
| Inflammation, Carotid Intima-Media Thickness, Atherosclerosis | Altered Intercellular Communication | The presence of subclinical atherosclerosis was investigated by ultrasound evaluation of common carotid intima-media thickness (ccIMT) and flow-mediated dilation (FMD); in addition, serum levels of lipids, inflammatory and coagulation parameters, as well as markers of endothelial inflammation and activation, were determined. | 22416009 |
| HD Term Type, Inflammation, Obesity, Cardiovascular Diseases | Altered Intercellular Communication | Inflammation, oxidative stress, and obesity are important features associated with pathogenesis of cardiovascular disease, a major contributor to the mortality of hemodialysis (HD) patients. | 22417287 |
| HD Term Type, Inflammation, Obesity | Altered Intercellular Communication | Thus, the purpose of this study was to analyze apelin plasma levels in HD patients and verify whether there is any relationship with inflammation, oxidative markers, and obesity. | 22417287 |
| Inflammation, Diabetes Mellitus, Non-Insulin-Dependent, Metabolic Syndrome X, Cardiovascular Diseases | Altered Intercellular Communication | High sensitivity C-reactive protein (hs-CRP), a marker of systemic inflammation and a predictor of type 2 diabetes and cardiovascular disease, is associated with the metabolic syndrome and its separate components. | 22417460 |
| Uveal melanoma, Inflammation | Altered Intercellular Communication | A range of significantly elevated angiogenic, inflammatory, and chemotactic cytokines in eyes with uveal melanoma supports the link between inflammation and tumorigenesis. | 22418780 |
| Inflammation, Sleep Apnea, Obstructive, Psoriasis | Altered Intercellular Communication | In our study, we aimed to investigate the frequency of OSAS in patients previously diagnosed with psoriasis in order to investigate a potential association between chronic inflammation psoriasis and OSAS. | 22418840 |
| Hallucinations, Visual | Altered Intercellular Communication | The pathophysiology of visual hallucinations may involve enhanced serotonergic neurotransmission. | 22419526 |
| Rupture, Arteritis | Altered Intercellular Communication | Nonetheless, our findings suggest that imaging of coronary artery inflammation is feasible, and further work evaluating (18)F-FDG uptake in high-risk coronary plaques prior to rupture would be of great interest. | 22419753 |
| ARCN1 gene, Inflammation, Chronic Obstructive Airway Disease | Altered Intercellular Communication | Fibrinogen is a marker of systemic inflammation and may be important in the pathogenesis and progression of chronic obstructive pulmonary disease (COPD). | 22419864 |
| Pneumoconiosis due to talc, Inflammation, Pneumoconiosis | Altered Intercellular Communication | Talcosis, a granulomatous inflammation of the lungs caused by inhalation of talcum dust, is a rare form of pneumoconiosis. | 22420484 |
| Diabetes Mellitus, Non-Insulin-Dependent, Inflammation, Periodontal Diseases | Altered Intercellular Communication | To determine the strength of association of type 2 diabetes mellitus and periodontal disease with the oral inflammatory burden, as assessed by markers of inflammation in saliva. | 22420648 |
| Intraocular inflammation | Altered Intercellular Communication | Intraocular inflammation and neurologic manifestations were controlled in all cases. | 22420960 |
| Intraocular Infection, Morbidity - disease rate, Inflammatory abnormality of the eye | Altered Intercellular Communication | Although ocular inflammation occurring after IOL implantation responds to corticosteroids, intraocular infections should always be taken into consideration to prevent severe ocular morbidity. | 22421095 |
| Rheumatoid Arthritis, Orchitis | Altered Intercellular Communication | Blockade of the interleukin-6 receptor (IL6R) with a monoclonal antibody (tocilizumab) licensed for treatment of rheumatoid arthritis reduces systemic and articular inflammation. | 22421340 |
| Inflammation, Rupture, Blood Clot, Plaque, Atherosclerotic, Embolism | Altered Intercellular Communication | Carotid artery-related stroke is largely an embolic disease that has been correlated with inflammation, plaque rupture, and thrombus formation in "vulnerable" atherosclerotic plaque. | 22422179 |
| Inflammation, Urinary Tract Physiology | Altered Intercellular Communication | Some lower urinary tract dysfunction (LUTD) subtypes may be associated with low-grade inflammation. | 22422219 |
| Granulomatous inflammation, Metallosis, Age related macular degeneration | Altered Intercellular Communication | ARMD is a spectrum of changes comprising of pure metallosis, ALVAL and granulomatous inflammation. | 22422805 |
| Prosthesis Failure, Necrosis | Altered Intercellular Communication | Lymphoid neogenesis documented in a variety of chronic inflammatory conditions most probably contributes to tissue necrosis and prosthetic failure seen in MoM hip arthroplasties. | 22422805 |
| Inflammation, Oligospermia | Altered Intercellular Communication | In addition, oligospermia, dilatation of the duct, and inflammation were frequently observed in the epididymides. | 22423049 |
| Inflammation, Depression, CTCAE | Altered Intercellular Communication | Heightened levels of inflammation may be associated with an increased risk of depression, particularly among those with inflammatory medical conditions. | 22424164 |
| Chronic kidney disease stage 5, Inflammation, Kidney Failure, Chronic, Depression, CTCAE | Altered Intercellular Communication | Although elevated rates of both systemic inflammation and depression have been documented among patients with end stage renal disease (ESRD), the link between these factors has received little empirical evaluation. | 22424164 |
| Rheumatic inflammation, Failure (biologic function), Thickened, Congenital Abnormality | Altered Intercellular Communication | The major causes for failure of rheumatic mitral valve repair are the presence of ongoing rheumatic inflammation at the time of surgery, use of inappropriate techniques, technical failures requiring early reoperation, lack of concomitant ring annuloplasty, and progression of leaflet and chordal disease further resulting in more leaflet retraction, thickening, and deformity. | 22424512 |
| Inflammation, Diabetes Mellitus | Altered Intercellular Communication | We tested whether diet-induced obesity, diabetes, and inflammation are associated with anti-bacterial IgG. | 22424821 |
| Appendage, Inflammation | Altered Intercellular Communication | Epiploic appendagitis is a rare, self-limiting inflammation of the epiploic appendices or omental appendices. | 22424988 |
| Inflammation, Thrombus, Ischemic stroke | Altered Intercellular Communication | The genetic basis of complex diseases like ischemic stroke probably consists of several predisposing risk factors, such as genes involved in inflammation and thrombotic pathways. | 22425140 |
| Inflammation, Paresthesia, Necrosis | Altered Intercellular Communication | Only transient complications of sclerotherapy were observed: local inflammation, perioral paresthesia in two patients, and necrosis of the mucosa of the cheek in one. | 22425358 |
| Inflammation, Disease remission, Insemination, Artificial, Homologous | Altered Intercellular Communication | However, we observed that the Treg frequency was significantly higher in those AIH patients with active disease than in those who were in a state of remission, suggesting that the Treg frequency may increase with the degree of inflammation. | 22425700 |
| Atherosclerosis | Altered Intercellular Communication | Atherosclerosis is a multifactorial disorder with chronic inflammatory conditions in which immune cells play a significant role in its pathogenic process. | 22426168 |
| Inflammation | Altered Intercellular Communication | Oxidized-LDL (ox-LDL), high-sensitivity C-reactive protein (hs-CRP) and the soluble intracellular adhesion molecule (ICAM) were chosen as biomarkers for systemic inflammation and oxidative damage. | 22426659 |
| Pain Distress Question, Inflammatory abnormality of the eye | Altered Intercellular Communication | A 6-year-old child presented with watering in the right eye for 3 days without ocular inflammation or pain. | 22427147 |
| Inflammation, Sleep Disorders | Altered Intercellular Communication | We concluded that inflammation has a close relation with sleep disorders in hemodialysis patients. | 22427289 |
| Inflammation, Chronic Obstructive Airway Disease | Altered Intercellular Communication | Because chronic obstructive pulmonary disease is characterized by low-grade systemic inflammation, we hypothesized that addition of inflammatory biomarkers to established predictive factors will improve accuracy. | 22427534 |
| Inflammation, Diabetic Retinopathy | Altered Intercellular Communication | Inflammation is a key causative factor in the pathogenesis of diabetic retinopathy. | 22427566 |
| Inflammation, Diabetes Mellitus | Altered Intercellular Communication | We speculate that the increased expression of GPR109A and elevation of its ligand b-HB in diabetes are mechanisms by which the tissue attempts to fight inflammation in this disease. | 22427566 |
| Pleurisy, Pleural effusion associated with pulmonary infection | Altered Intercellular Communication | Hyaluronic acid (HA) is a component of extracellular matrix and may play a role in the pleural inflammation which is implicated in parapneumonic effusions.The aim of the current study was to investigate HA levels in serum and pleura in patients with parapneumonic effusions. | 22428219 |
| Inflammation | Altered Intercellular Communication | Matrix metalloproteinases (MMPs) induce leukocyte migration into inflammation sites that lead to either promotion or repression of inflammation by activating or inactivating cytokines. | 22428754 |
| Inflammation, Lower Urinary Tract Symptoms | Altered Intercellular Communication | Accumulating evidence suggests that inflammation may contribute to the development of BPH and LUTS. | 22429766 |
| Inflammation, Nocturia, Lower Urinary Tract Symptoms, Benign prostatic hypertrophy | Altered Intercellular Communication | To investigate the relationship between non-steroidal anti-inflammatory drug (NSAID) use and the incidence of benign prostatic hyperplasia (BPH)-related outcomes and nocturia, a lower urinary tract symptom (LUTS) of BPH, in light of accumulating evidence suggesting a role for inflammation in BPH/LUTS development. | 22429766 |
| Refractory Cytopenia of Childhood, Cystitis, Neoplasms | Altered Intercellular Communication | Up-regulated miRNA 15a can be measured in urine from patients with RCC but is nearly undetectable in oncocytoma, other tumors, and urinary tract inflammation. | 22429968 |
| Inflammation, immunoglobulin A | Altered Intercellular Communication | Chronic parodontit inflammation in elderly patients was found to be accompanied by inbalance of complement system; IgA (sIgA), IgA, IgG, IgM hyperproduction; the increase of IL-8, IL-1a concentration and decrease of IL-4 level; increase Hsp-70 antibodies. | 22433635 |
| PODXL2 gene, Inflammation, Gastroenteritis, Eosinophilic inflammation | Altered Intercellular Communication | Eosinophilic gastroenteritis (EG) is an inflammation of the digestive tract that is characterized by eosinophilic infiltration. | 22433795 |
| Inflammation, Cerebrovascular accident | Altered Intercellular Communication | Data of literature on the role of inflammation factors in the pathogenesis of stroke are presented. | 22433805 |
| Infarction, Inflammation | Altered Intercellular Communication | It has been shown that the activation of systemic inflammation and related oxidative stress recorded in the early acute phase of brain infarction needs pharmacological treatment. | 22433805 |
| Barrett Esophagus, Dysplasia, Esophagitis | Altered Intercellular Communication | Distribution of body fat and its influence on esophageal inflammation and dysplasia in patients with Barrett's esophagus. | 22433923 |
| Dysplasia, Esophagitis | Altered Intercellular Communication | We investigated the distribution of fat in subjects with BE and its association with esophageal inflammation and dysplasia. | 22433923 |
| Dysplasia, Esophagitis | Altered Intercellular Communication | Esophageal inflammation (based on a histologic score) and dysplasia grade were assessed from esophageal biopsies of BE cases by a gastrointestinal pathologist. | 22433923 |
| Dysplasia, Esophagitis | Altered Intercellular Communication | Visceral and GEJ fat were significantly greater in BE subjects with esophageal inflammation (compared with those without, P = .02) and high-grade dysplasia (compared with those without, P = .01), independent of BMI. | 22433923 |
| Dysplasia, Esophagitis | Altered Intercellular Communication | GEJ and visceral fat are associated with BE, and with increased esophageal inflammation and high-grade dysplasia in BE subjects, independent of BMI. | 22433923 |
| Liver carcinoma | Altered Intercellular Communication | A novel, externally validated inflammation-based prognostic algorithm in hepatocellular carcinoma: the prognostic nutritional index (PNI). | 22433965 |
| Inflammation, deficiency aspects | Altered Intercellular Communication | Inflammation was clearly associated with the observed TST deficiency. | 22434643 |
| Crohn Disease, Acute inflammation | Altered Intercellular Communication | Recent work provides evidence of a failure of acute inflammation in Crohn's disease (CD), and suggests that the primary defect operates at the level of the macrophage and cytokine release. | 22434667 |
| Inflammation, Bronchoconstrictor Agents | Altered Intercellular Communication | Although leukotriene D4 (LTD4) is a potent bronchoconstrictor, little is known about airway responsiveness to LTD4 in asthmatics with different inflammation phenotypes. | 22435894 |
| Inflammation, Fever, CTCAE, Abdominal guarding (finding) | Altered Intercellular Communication | There was no fever or muscular guarding, and no signs of inflammation in the blood screening. | 22436521 |
| Inflammation, Observation Method - Coagulation, Traumatic injury | Altered Intercellular Communication | Injured adult patients eligible for enrolment in the Activation of Coagulation and Inflammation in Trauma 2 study, and admitted to the intensive care unit between January 2008 and January 2010, were selected retrospectively for the study. | 22437496 |
| Osteopenia | Altered Intercellular Communication | Disuse is the primary cause for bone loss, although neural and hormonal changes may also contribute via different mechanisms. | 22437628 |
| Inflammation, Arteriosclerosis | Altered Intercellular Communication | Our results suggest that subjects who have mild inflammation related to arteriosclerosis have decreased regional gray matter volume in the posterior and lateral aspects of the left temporal cortex. | 22438310 |
| Inflammation | Altered Intercellular Communication | It is unclear whether these changes result from chronic inflammation or whether they represent early events in the gluten response. | 22438948 |
| ARCN1 gene, Inflammation | Altered Intercellular Communication | b2 long-acting and anticholinergic drugs control TGF-b1-mediated neutrophilic inflammation in COPD. | 22440430 |
| Cerebrovascular, "Alzheimers Disease | Altered Intercellular Communication | Early cerebrovascular inflammation in a transgenic mouse model of Alzheimer's disease. | 22440674 |
| Inflammation, Data types - Address, Nerve Degeneration | Altered Intercellular Communication | Inflammation contributes to neurodegeneration at later stages of AD, but it may also play a role in early disease pathogenesis. | 22440674 |
| Cerebrovascular, Dental Plaque, Data types - Address | Altered Intercellular Communication | We found that before plaque deposition, amyloid precursor protein (APP)/presenilin 1 (PSEN1) transgenic mice (PSAPP mice), a well-characterized model of AD, exhibit evidence of cerebrovascular inflammation. | 22440674 |
| Cerebrovascular | Altered Intercellular Communication | Our study indicates that MECA-32 may be a robust marker of cerebrovascular inflammation and compromised BBB integrity, triggered by soluble amyloid-b early in disease pathogenesis. | 22440674 |
| Pancreatitis, Diabetes Mellitus, Non-Insulin-Dependent | Altered Intercellular Communication | Both GLP-1 receptor agonists and DPP-4 inhibitors are associated with increased levels of serum lipase more than serum amylase in many patients with type 2 diabetes, possibly suggesting the presence of pancreatic inflammation. | 22440997 |
| Inflammation, Diabetes Mellitus, Non-Insulin-Dependent | Altered Intercellular Communication | Podocyte as a potential target of inflammation: role of pioglitazone hydrochloride in patients with type 2 diabetes. | 22441004 |
| Diabetes Mellitus, Non-Insulin-Dependent, Nephritis | Altered Intercellular Communication | Pioglitazone treatment revealed a podocyte-protective capacity in patients with type 2 diabetes, and the underlying mechanisms may be partly attributed to its effective suppression of excessive local renal inflammation. | 22441004 |
| Inflammation, Hypertensive (finding), Atrial Fibrillation by ECG Finding | Altered Intercellular Communication | Subclinical inflammation may be associated with delayed/inhomogeneous atrial activation in hypertensive patients affected by atrial fibrillation. | 22441219 |
| Inflammation, Liver Cirrhosis | Altered Intercellular Communication | Inflammation may be implicated in the haemodynamic deterioration and in the development of complications in patients with cirrhosis. | 22441510 |
| Inflammation, Coronary Arteriosclerosis | Altered Intercellular Communication | High-sensitivity C-reactive protein (hsCRP) is a marker of low-grade inflammation, and predicts outcomes in patients at risk of ischaemic heart disease. | 22441510 |
| Inflammation, Liver Cirrhosis | Altered Intercellular Communication | We investigated a possible association between markers of inflammation and splanchnic and systemic haemodynamics, complications and survival in patients with cirrhosis. | 22441510 |
| ARCN1 gene, Inflammation | Altered Intercellular Communication | Reduced nuclear factor-kB repressing factor: a link toward systemic inflammation in COPD. | 22441735 |
| ARCN1 gene, Inflammation, Chronic Obstructive Airway Disease | Altered Intercellular Communication | Chronic systemic inflammation is implicated in the systemic manifestations and, probably, the excess mortality risk of chronic obstructive pulmonary disease (COPD). | 22441735 |
| ARCN1 gene, Inflammation | Altered Intercellular Communication | NRF expression is reduced in PBMCs of stable COPD patients, probably through oxidative stress, leading to increased production of IL-8/CXCL8 and potentially chronic systemic inflammation. | 22441735 |
| Airway structure, Allergic | Altered Intercellular Communication | Recent evidence shows that this treatment also improves airway inflammation in nonallergic patients. | 22441741 |
| Nephritis | Altered Intercellular Communication | Our data suggest that in the acute stage of the disease neutrophils may act as an important immediate-early innate source of IL-17 and may thereby initiate and promote ongoing renal inflammation. | 22442208 |
| Inflammation, diabetic | Altered Intercellular Communication | Systemic inflammation is thought to have a central role in diabetic long-term complications. | 22442277 |
| Data types - Address | Altered Intercellular Communication | Our results demonstrate increased IFN-g responses in skin of patients with AD and suggest involvement of multiple new apoptosis- and inflammation-related factors in the development of AD. | 22445417 |
| Intraocular inflammation | Altered Intercellular Communication | Upon starting anti-toxoplasmic therapy (ATT), her intraocular inflammation resolved with catastrophic damage to the disc and macula. | 22446913 |
| Inflammation, Carotid Stenosis, Dental Plaque | Altered Intercellular Communication | Our results show a close association between neovascularization, expression of angiogenic factors, inflammation, and plaque vulnerability in patients with advanced carotid stenosis. | 22447000 |
| Inflammation, Metabolic Syndrome X | Altered Intercellular Communication | The developmental trajectory between early life stress and inflammation appears not to be mediated by metabolic syndrome associated factors in our sample. | 22447087 |
| Inflammation, Fibrosis Assessment, Hypertrophic Cardiomyopathy | Altered Intercellular Communication | Low-grade inflammation and the phenotypic expression of myocardial fibrosis in hypertrophic cardiomyopathy. | 22447464 |
| Inflammation, Fibrosis Assessment, Health maintenance, Hypertrophic Cardiomyopathy | Altered Intercellular Communication | To investigate the role of inflammation in the phenotypic expression of myocardial fibrosis in hypertrophic cardiomyopathy (HCM). | 22447464 |
| Inflammation, Acute Coronary Syndrome | Altered Intercellular Communication | Markers of inflammation and intracellular metabolism of neutrophils in patients with acute coronary syndrome and normal troponin T levels. | 22448368 |
| Inflammation, Acute Coronary Syndrome, Endothelial dysfunction | Altered Intercellular Communication | Markers of inflammation and intracellular metabolism of neutrophils were studied in 58 patients with acute coronary syndrome with different levels of troponin T. In patients with repeated coronary events within a year, more pronounced endothelial dysfunction associated with activation of oxygen-dependent metabolism of neutrophils and lipid peroxidation process was revealed at admission to the hospital. | 22448368 |
| Aneurysm, ASAH1 gene, Inflammation | Altered Intercellular Communication | Cerebral microdialysis probes were placed in brain parenchyma of the respective vascular territory of the aneurysm in 21 consecutive aSAH patients, enrolled in a prospective study on inflammation. | 22449315 |
| Degenerative polyarthritis, Inflammation | Altered Intercellular Communication | Recent evidences suggest that inflammation contributes to the development and progression of osteoarthritis (OA). | 22449335 |
| Tumor necrosis, Leucocytic infiltrate, Data types - Address, Inflammation | Altered Intercellular Communication | Vascular endothelial growth factor (VEGF), transforming growth factor b (TGF-b), and tumor necrosis factor a (TNF -a) may play important roles in inflammation and angiogenesis through effects on inflammatory cell infiltration or neovascularization in AD pathogenesis. | 22449478 |
| Inflammation, Endothelial dysfunction | Altered Intercellular Communication | It has been reported to be associated with inflammation and endothelial dysfunction. | 22449661 |
| Granulomatosis, Inflammation, Granulomatosis with polyangiitis, Systemic Vasculitis | Altered Intercellular Communication | A key feature of granulomatosis with polyangiitis (GPA; or Wegener's granulomatosis) is the granulomatous inflammation of the upper respiratory tract, which leads to the subsequent destruction of adjacent tissues. | 22449947 |
| Irvine-Gass Syndrome, Inflammation, Hyphema, Cataract | Altered Intercellular Communication | Twenty five-gauge group achieved a significantly lower anterior chamber inflammation and a lower incidence of postoperative cystoid macular edema (CME) (p=0.01), hyphema (p=0.000) and after cataract (p=0.000) than 20-gauge group. | 22449995 |
| Acute inflammation | Altered Intercellular Communication | The 25-gauge sutureless vitrectomy achieves rapid and higher visual improvement, less postoperative inflammation and complications than the 20-gauge vitrectomy in ERM surgery. | 22449995 |
| Inflammation | Altered Intercellular Communication | Taken together, these data suggest that valvular DNA-damage pathways may be associated with inflammation and the stenosis severity in tricuspid aortic valves. | 22450322 |
| Neurocognitive Disorders, Inflammation, Hand | Altered Intercellular Communication | In spite of antiretroviral therapy (ART), patients continue to be at risk for HIV-associated neurocognitive disorders (HAND), which might be related to persistence of inflammation. | 22450616 |
| Inflammation, liposarcoma, Pseudotumor | Altered Intercellular Communication | We believe that the inflammatory pseudotumor complicated in repairing the inflammation arising from the liposarcoma. | 22450833 |
| Inflammation, Appendicitis, CTCAE | Altered Intercellular Communication | Although appendicitis is one of the most common causes of emergency surgery, parasites are rarely found associated with inflammation of the appendix. | 22450920 |
| Inflammation | Altered Intercellular Communication | The findings suggest that YKL-40 might be implicated in the pathogenesis of the disease and could indicate the level of joint inflammation. | 22451025 |
| Inflammation, Dry cough | Altered Intercellular Communication | The 2 patients sought attention because of chronic dry cough associated with inflammation of unknown origin. | 22451028 |
| Seizures, Inflammation | Altered Intercellular Communication | Thirty-two patients with an exclusive (n=11) or predominant (n=21) seizure presentation in whom an autoimmune etiology was suspected (on the basis of neural autoantibody [91%], inflammatory cerebrospinal fluid [31%], or magnetic resonance imaging suggesting inflammation [63%]) were studied. | 22451162 |
| ARCN1 gene, Inflammation, Asthma, Chronic Obstructive Airway Disease | Altered Intercellular Communication | The objective of our study was to investigate whether the profile of eicosanoid lipid mediators in EBC can characterize the inflammation in asthma and chronic obstructive pulmonary disease (COPD). | 22451217 |
| Leukopenia, Septicemia | Altered Intercellular Communication | A significant influence on leukopenia and febrile septicemia has been shown for several comorbidities, especially chronic inflammation. | 22451304 |
| Alzheimers Disease", Data types - Address | Altered Intercellular Communication | The mode of action of acetylcholinesterase inhibitors (AChEIs) in Alzheimer's disease (AD) is mainly by potentiating neuronal transmission. | 22451323 |
| Inflammation, Fibrosis Assessment | Altered Intercellular Communication | We found an association between donor liver fibrosis and patient survival (p = 0.016) as well as between graft survival and portal inflammation in the donor liver (p = 0.026). | 22452366 |
| Inflammation, Fibrosis Assessment | Altered Intercellular Communication | Histopathological features, especially portal inflammation and stage of fibrosis, in the donor liver may deleteriously affect graft and patient survival following HCV-related liver transplantation. | 22452366 |
| Inflammation | Altered Intercellular Communication | Humoral mediators of inflammation, in particular the complement system, have been described to play an important role in atherogenesis. | 22452399 |
| glycation, Pneumonitis | Altered Intercellular Communication | Soluble receptor for advanced glycation end products (sRAGE) is present at high concentrations in the lungs of children and varies with age and the pattern of lung inflammation. | 22452564 |
| glycation, Inflammation | Altered Intercellular Communication | The soluble receptor for advanced glycation end products (sRAGE) plays an important role in inflammation. | 22452564 |
| Inflammation, Subarachnoid Hemorrhage | Altered Intercellular Communication | Repeated cranial CT did not show subarachnoid hemorrhage; CSF examination showed neither xanthochromia nor inflammation. | 22453044 |
| Inflammation, Fever of Unknown Origin, Fever, CTCAE, Vasculitis, CTCAE | Altered Intercellular Communication | PET/CT is starting to play an important role in evaluating fever of unknown origin (FUO), due to its ability to localize and delineate areas of high metabolic activity, such as neoplastic proliferation and inflammation, including vasculitis. | 22453531 |
| Stomach Carcinoma, Neoplasms | Altered Intercellular Communication | Chronic allergic-like inflammation in the tumor stroma of human gastric carcinomas: an ultrastructural study. | 22455876 |
| Inflammation, Intradermal Route of Drug Administration | Altered Intercellular Communication | Values either were adjusted for inflammation [as measured by C-reactive protein (> 5 mg/L) and a(1)-acid glycoprotein (> 1 g/L) before applying cutoffs for ID] or were unadjusted. | 22456661 |
| Inflammation, Intradermal Route of Drug Administration | Altered Intercellular Communication | TfR better estimates the prevalence of ID in preschoolers than do ferritin, ZP, and the TfR/ferritin index on the basis of multiple indexes in a high inflammation, resource-poor setting. | 22456661 |
| HD Term Type, Inflammation | Altered Intercellular Communication | VDRA supplementation may suppress chronic inflammation and have some advantage for mortality of HD patients with vitamin D deficiency. | 22457088 |
| Alzheimers Disease", Inflammation | Altered Intercellular Communication | Inflammation of the brain is strongly implicated in Alzheimer's disease which could be enhanced by systemic inflammation. | 22458804 |
| Inflammation, Periodontitis, "Alzheimers Disease | Altered Intercellular Communication | Periodontitis being a chronic inflammatory condition, which can cause systemic inflammation, the question is whether chronic periodontitis can initiate or hasten the rate of progression of Alzheimer's disease in susceptible individuals. | 22458804 |
| Inflammation, Periodontitis, "Alzheimers Disease | Altered Intercellular Communication | Periodontitis being a chronic inflammatory condition, which can cause systemic inflammation, the question is whether chronic periodontitis can initiate or hasten the rate of progression of Alzheimer's disease in susceptible individuals. | 22458804 |
| ARCN1 gene, Inflammation | Altered Intercellular Communication | Effect of bronchial colonisation on airway and systemic inflammation in stable COPD. | 22458940 |
| Bronchial brand of guaifenesin-theophylline, Inflammation, ARCN1 gene | Altered Intercellular Communication | The objective of this study was to determine the relationships between bronchial colonisation and both bronchial and systemic inflammation in stable COPD. | 22458940 |
| Inflammation, Lymphoma | Altered Intercellular Communication | The main reason for the development of these cysts might be the accompanying inflammation of the lymphoma. | 22459556 |
| Asthmatic Airway Remodeling | Altered Intercellular Communication | Asthma is common in elite canoe and kayak athletes, and classical signs of asthmatic airway inflammation are also found in asymptomatic athletes. | 22459716 |
| Inflammation, Albuminuria, Functional Disability, Cardiovascular Diseases | Altered Intercellular Communication | Chronic inflammation, albuminuria, and functional disability in older adults with cardiovascular disease: the National Health and Nutrition Examination Survey, 1999-2008. | 22460050 |
| Disability, Inflammation, Albuminuria | Altered Intercellular Communication | We found combined association of inflammation and albuminuria with disability and with metabolic risks. | 22460050 |
| Disability, Inflammation, Albuminuria | Altered Intercellular Communication | There is a combined association of inflammation and albuminuria on multiple domains of disability and metabolic risks, suggesting the presence of elevated UACR may amplify the association of inflammation with disability and with metabolic risk in older adults living with CVD. | 22460050 |
| Heart failure | Altered Intercellular Communication | Heart failure and malnutrition/inflammation are prognostic factors related to mortality in these patients on chronic hemodialysis. | 22460181 |
| Sepsis, Inflammation, Organ Dysfunction Scores | Altered Intercellular Communication | Asymmetric dimethylarginine was decreased in pediatric sepsis and was inversely associated with inflammation and organ dysfunction. | 22460770 |
| Inflammation, Prostate, Prostate carcinoma | Altered Intercellular Communication | Inflammation and preneoplastic lesions in benign prostate as risk factors for prostate cancer. | 22460812 |
| Inflammation, Prostatic Intraepithelial Neoplasias, Atrophic | Altered Intercellular Communication | Benign changes ranging from atrophy and inflammation to high-grade prostatic intraepithelial neoplasia (HGPIN) are common findings on prostate core needle biopsies. | 22460812 |
| Inflammation, Atrophic, Prostate carcinoma | Altered Intercellular Communication | Although atrophy and inflammation may be precursors of prostate cancer, only HGPIN is currently recommended to be included in surgical pathology reports. | 22460812 |
| Inflammation, Atrophic | Altered Intercellular Communication | The initial benign specimen was reviewed for presence of HGPIN, atrophy (simple, lobular, and partial) and inflammation (glandular and/or stromal). | 22460812 |
| Inflammation, Atrophic, Prostate carcinoma | Altered Intercellular Communication | In a model adjusted for prostate-specific antigen (PSA) level at cohort entry and inflammation, simple atrophy was associated with a 33% increased prostate cancer risk that was marginally significant (P=0.03). | 22460812 |
| Cerebrovascular accident | Altered Intercellular Communication | Carotid plaque inflammation on 18F-fluorodeoxyglucose positron emission tomography predicts early stroke recurrence. | 22461139 |
| Rupture, Thromboembolism | Altered Intercellular Communication | Current carotid imaging techniques rely on estimating plaque-related lumen narrowing but do not evaluate intraplaque inflammation, a key mediator of plaque rupture and thromboembolism. | 22461139 |
| Carotid Stenosis, Cerebrovascular accident | Altered Intercellular Communication | In recently symptomatic carotid stenosis, inflammation-related FDG uptake was associated with early stroke recurrence, independent of the degree of stenosis. | 22461139 |
| Diabetic Nephropathy, Inflammation, glycation | Altered Intercellular Communication | Effects of sevelamer on HbA1c, inflammation, and advanced glycation end products in diabetic kidney disease. | 22461535 |
| Inflammation | Altered Intercellular Communication | Increased inflammation and oxidative stress may be caused by proteins and lipids modified by cytotoxic advanced glycation end products (AGEs) in food. | 22461535 |
| Inflammation, Kidney Diseases, Diabetes Mellitus | Altered Intercellular Communication | Sevelamer carbonate significantly reduces HbA1c, fibroblast growth factor 23, lipids, and markers of inflammation and oxidative stress, and markedly increases antioxidant markers, independently of phosphorus in patients with diabetes and early kidney disease. | 22461535 |
| Inflammation, Breast Carcinoma | Altered Intercellular Communication | Research into the etiology of breast cancer has recently focused on the role of the immunity and inflammation. | 22461912 |
| Inflammation, Primary malignant neoplasm | Altered Intercellular Communication | The proinflammatory cytokines IL-17A and IL-17F can mediate inflammation and cancer. | 22461912 |
| Troponin T, Cardiac Muscle, Inflammation | Altered Intercellular Communication | Laboratory investigations revealed normal serum cardiac troponin T and serum potassium, and absence of inflammation signs. | 22462353 |
| Inflammation, Fibrosis Assessment, Atherosclerotic aneurysm | Altered Intercellular Communication | CT findings, laboratory tests and finally, histopathologic examination showed atherosclerotic aneurysm without inflammation and retroperitoneal fibrosis. | 22462354 |
| Chronic lymphocytic inflammation, Polyarteritis Nodosa | Altered Intercellular Communication | It was seen in a variable number of small- to medium-sized parenchyma arteries with segmental to transmural lymphocytic inflammation, within the morphological spectrum of a polyarteritis nodosa (PAN)-like lesion seen at the periphery of BPH nodules. | 22462607 |
| Inflammation, Dental Plaque | Altered Intercellular Communication | Chronic inflammation was found superficially in 59/125 plaques (47%) and deeply inside the plaque tissue in 103/125 plaques (83%). | 22463585 |
| Inflammation, Hemorrhage | Altered Intercellular Communication | Moreover, microvascular CD105 positivity correlated positively with plaque haemorrhage and deeply seated plaque inflammation. | 22463585 |
| Inflammation, Hemorrhage, Coronary Arteriosclerosis | Altered Intercellular Communication | Plaque inflammation and haemorrhages can be found at a high frequency throughout the coronary artery system of elderly patients with multivessel coronary atherosclerosis. | 22463585 |
| Inflammation, Herpetic Gastritis | Altered Intercellular Communication | Most patients with herpetic scleritis presented with acute (85.7%) and unilateral (80%) scleral inflammation. | 22463821 |
| Inflammation, Primary malignant neoplasm, Cancer Pain | Altered Intercellular Communication | Although recent studies have suggested a relationship between single nucleotide polymorphisms (SNPs) in several cytokine and inflammation genes with cancer prognosis, associations with cancer pain are not clear. | 22464751 |
| Inflammation, Dental Plaque, Atherosclerotic lesion | Altered Intercellular Communication | Inflammation plays an essential role in the development and progression of atherosclerotic lesions, and plaque disruption. | 22465044 |
| Inflammation, Fever, CTCAE | Altered Intercellular Communication | Systemic inflammation, including fever, was a characteristic manifestation of the AEs in CTD patients, particularly those with anti-RNP antibody. | 22466117 |
| Inflammation, Fever, CTCAE | Altered Intercellular Communication | Systemic inflammation, including fever, might be a characteristic feature of the AEs in CTD patients, particularly those with anti-RNP antibody. | 22466117 |
| Inflammation | Altered Intercellular Communication | Subsequently in reproductive age they are developed usually against hypoestrogenomia; however the physiological reduction in estrogen levels during menopause by itself contributes to impairment of metabolism and intensification of inflammation (inflammatory markers CPR, ALT), oxidative stress (O(2)(-), LOO*), hipoxia (HBNO) and all related compititions (increase vascular resistence, disorders in oxygen suplay in tissue and hypoxic compititions of there metabolism). | 22466534 |
| Inflammation, Myocardial | Altered Intercellular Communication | Leukocyte filtration of blood cardioplegia attenuates myocardial damage and inflammation. | 22466697 |
| Autoimmune Diseases, Inflammation | Altered Intercellular Communication | We started steroid administration after the fourth PCI to reduce inflammation due to autoimmunity. | 22466830 |
| Inflammation, Malnutrition, palladium, Hypertension, CTCAE, Chronic Kidney Diseases | Altered Intercellular Communication | Overhydration as assessed by ECW/TBW is prevalent in adult PD patients, and is associated with loss of residual renal function, inflammation, malnutrition and hypertension - as assessed by antihypertensive medications. | 22466994 |
| Inflammation, Cachexia, Chronic Kidney Diseases | Altered Intercellular Communication | As this was a retrospective cross-sectional audit, whether loss of residual renal function, inflammation, and protein energy wasting lead to volume expansion remains to be determined in prospective longitudinal studies. | 22466994 |
| Inflammation, Perforation (observation) | Altered Intercellular Communication | In order to avoid imminent perforation, a hemicolectomy became necessary, and immediately the symptoms and inflammation markers normalized rapidly. | 22467540 |
| Inflammation, BRCA1 wt Allele | Altered Intercellular Communication | We assume that the severe inflammation was caused by an immune restoration inflammatory syndrome (IRIS). | 22467540 |
| Inflammation, Failure, pathologic fistula | Altered Intercellular Communication | Postoperative CD (pouch inflammation into the afferent limb or pouch fistula) or pouch failure (need for permanent diversion) were assessed. | 22467562 |
| Inflammation | Altered Intercellular Communication | Afferent limb inflammation developed in three (50%) of the six patients with pANCA+/OmpC- expression compared to none of the 11 patients without this serologic profile (P = 0.03). | 22467562 |
| Abnormal circulating valine concentration, Inflammation | Altered Intercellular Communication | Metabolic abnormality and systemic inflammation may be the risk factors. | 22467841 |
| Inflammation | Altered Intercellular Communication | The aspirin-induced bronchospasm is mediated by mast cell and eosinophilic inflammation. | 22468095 |
| Inflammation, Malnutrition | Altered Intercellular Communication | Malnutrition and inflammation are related to high rates of morbidity and mortality in hemodialysis patients. | 22468100 |
| Deposition | Altered Intercellular Communication | Kidney biopsy showed mesangial proliferation and IgA deposits with tubulointerstitial inflammation. | 22468111 |
| Inflammation, Metabolic Syndrome X, Obesity | Altered Intercellular Communication | In men, obesity and the metabolic syndrome are accompanied by decreased testosterone levels, but little is known about the associations between visceral adipose tissue (VAT), VAT-related inflammation and sex steroids. | 22469460 |
| Inflammation, Hypogonadism, Metabolic Syndrome X | Altered Intercellular Communication | The significant inverse association between IL-6 and T suggests an important role of low-grade visceral fat inflammation in the central hypogonadism associated with the metabolic syndrome. | 22469460 |
| Inflammation, Tumor necrosis, Diverticular Diseases | Altered Intercellular Communication | Inflammation occurs in diverticular disease (DD), but there is little information on inflammatory cytokines such as tumour necrosis factor a (TNF-a). | 22469482 |
| Inflammation, Data types - Address | Altered Intercellular Communication | In particular, it appears to be overexpressed in DD with inflammation (AUD and SUDD) compared with DD without (AD). | 22469482 |
| Inflammation, Diabetes Mellitus, Non-Insulin-Dependent, Fatigue | Altered Intercellular Communication | Fatigue symptoms relate to systemic inflammation in patients with type 2 diabetes. | 22469909 |
| Inflammation, Diabetes Mellitus, Non-Insulin-Dependent, Fatigue | Altered Intercellular Communication | Chronic inflammation represents one characteristic of type 2 diabetes that may contribute to fatigue symptoms. | 22469909 |
| Inflammation, Diabetes Mellitus, Non-Insulin-Dependent, Fatigue | Altered Intercellular Communication | These findings indicate that systemic low-grade inflammation relates to fatigue symptoms in patients with type 2 diabetes and suggest the involvement of inflammatory processes in the pathophysiology of diabetes-related fatigue. | 22469909 |
| Inflammation, Pain Distress Question | Altered Intercellular Communication | The cause is secondary to microabrasive wear and shedding of any portion of the prosthesis, and the microscopic foreign bodies activate inflammation which can lead to pain. | 22470793 |
| palladium, Tumor necrosis, Inflammation, Atherosclerosis | Altered Intercellular Communication | Tumour necrosis factor-related apoptosis-inducing ligand (TRAIL) can counteract inflammation and atherosclerosis, both common causes of morbidity in peritoneal dialysis (PD) patients. | 22471587 |
| Inflammation, Cardiovascular Diseases | Altered Intercellular Communication | Inflammation may be a mechanism linking socioeconomic position (SEP) with cardiovascular disease. | 22472036 |
| Inflammation, "Alzheimers Disease | Altered Intercellular Communication | A growing body of evidence indicates that inflammation is one of the earliest neuropathological events in Alzheimer's disease. | 22472085 |
| Inflammation | Altered Intercellular Communication | A higher concentration of CD34(+) cells and a lower degree of inflammation are associated with better clinical therapeutic responses. | 22472173 |
| Inflammation, Metabolic Diseases, Injury of liver | Altered Intercellular Communication | Associations between markers of liver injury and cytokine markers for insulin sensitivity and inflammation in middle-aged Japanese men not being treated for metabolic diseases. | 22472283 |
| Gastrointestinal Stromal Tumors, Fibrosis Assessment, Inflammation | Altered Intercellular Communication | Pathological examination revealed four cases of gastrointestinal stromal tumor and one case of inflammatory fibrosis caused by nonspecific inflammation. | 22472403 |
| Inflammation, Electrocardiogram: myocardial infarction (finding), Respiratory Failure, Pulmonary Edema, CTCAE | Altered Intercellular Communication | The role of inflammation associated with pulmonary edema as a cause of acute respiratory failure post-acute myocardial infarction remains to be determined. | 22473400 |
| Inflammation | Altered Intercellular Communication | Interleukin (IL)-22 is known to play a key role in promoting antimicrobial immunity, inflammation, and tissue repair at barrier surfaces by binding to the receptors, IL-10R2 and IL-22R1. | 22473749 |
| Inflammation, Weight decreased, Cachexia | Altered Intercellular Communication | We analyzed 129 single nucleotide polymorphisms (SNPs) in 80 genes for association with cachexia based on degree of weight loss (>5, >10, >15%) as well as weight loss in the presence of systemic inflammation (C-reactive protein, > 10 mg/l). | 22473907 |
| Malignant neoplasm of liver, Inflammation, Fibrosis Assessment, Hepatocarcinogenesis | Altered Intercellular Communication | The results showed that the altered genes in FXR(-/-) livers were mainly related to metabolism, inflammation, and fibrosis, which suggest that hepatocarcinogenesis in FXR(-/-) mice recapitulated the progression of human liver cancer. | 22474109 |
| diabetic | Altered Intercellular Communication | In conclusion, circulating progenitor cells of diabetic patients show a phenotypic drift toward a pro-calcific phenotype that may be driven by inflammatory signals. | 22474430 |
| Inflammation, Aortic valve calcification, Aortic Valve Stenosis | Altered Intercellular Communication | Aortic valve stenosis (AS) is an actively regulated pathobiological process which has an inflammation origin, and manifests as an accumulation of lipids and, ultimately, calcification of the aortic valve tissue. | 22474738 |
| Inflammation, Arteriopathic disease, Corneal Endothelial Cell Loss | Altered Intercellular Communication | We hypothesised that chronic condition of arterial disease engenders inflammation and endothelial damage in response to circulating cytokines released in the blood stream of PAD patients. | 22475098 |
| Inflammation, Fibrosis Assessment | Altered Intercellular Communication | Effective management of patients affected by retroperitoneal fibrosis (RPF) is an important issue because of lack of relevant parameters to objectively assess the degree of inflammation. | 22475894 |
| Inflammation, Bursitis | Altered Intercellular Communication | We propose diffuse uptake may reflect ligament inflammation with focal uptake in adjacent interspinous bursitis. | 22475905 |
| Esophagitis | Altered Intercellular Communication | All patients underwent an upper endoscopy to determine if esophageal inflammation was present or absent. | 22476040 |
| Inflammation, Pancreatic carcinoma | Altered Intercellular Communication | Comparison of the prognostic values of various inflammation based factors in patients with pancreatic cancer. | 22476808 |
| Inflammation, Electrocardiogram: myocardial infarction (finding) | Altered Intercellular Communication | Correlations between serum inflammation factors and left ventricular remodeling in acute ST segment elevation myocardial infarction. | 22476992 |
| Inflammation, Electrocardiogram: myocardial infarction (finding) | Altered Intercellular Communication | To investigate the changes and correlations of the serum inflammation factors levels and left ventricular (LV) structure and function in patients with acute ST segment elevation myocardial infarction (STEMI). | 22476992 |
| Optic Neuritis, Optic perineuritis | Altered Intercellular Communication | Inflammation of the optic nerve (optic neuritis) and its sheath (optic perineuritis) can have similar initial clinical presentations. | 22477734 |
| Lynch Syndrome, Colorectal Carcinoma | Altered Intercellular Communication | Our study demonstrates that colorectal carcinoma is not infrequently diagnosed in patients <=40 years of age and is not frequently the result of underlying Lynch syndrome or associated with other cancer-predisposing genetic conditions or chronic inflammatory conditions. | 22481281 |
| Inflammation | Altered Intercellular Communication | Association between butyrylcholinesterase activity and low-grade systemic inflammation. | 22481455 |
| Inflammation, Acute inflammation | Altered Intercellular Communication | In male patients with subclinical chronic inflammation and hsCRP concentrations < 1 mg/L, a significant positive correlation was observed between BChE and hsCRP (p < 0.02); however, for hsCRP concentrations > 3 mg/L, the correlation between these variables in both sexes becomes significantly negative (p < 0.001), as in patients with acute inflammation (hsCRP > 10 mg/L). | 22481455 |
| Inflammation | Altered Intercellular Communication | The liver production of BChE and albumin occurs in a coupled fashion, and these biochemical variables may be considered as negative inflammatory reactants, whose serum levels are inversely associated with the increasing degree of subclinical inflammation. | 22481455 |
| Cholesteatoma, Inflammation | Altered Intercellular Communication | The middle ear cholesteatoma, an aural epidermal pathology characterized by keratinocyte hyperproliferation and chronic inflammation, may represent a model condition to study the epithelial-mesenchymal interactions. | 22481617 |
| Borrelia Infections, Inflammation, Tularemia, Tick-Borne Lymphadenopathy | Altered Intercellular Communication | However, resistance to antibiotics and the absence of inflammation militated against this diagnosis, and other possible diagnoses such as a tick-borne lymphadenopathy (TIBOLA), borreliosis and tularaemia were discussed. | 22482480 |
| APP gene, Inflammation, Aortic Aneurysm, Abdominal | Altered Intercellular Communication | Angiopoietin-2 (Angpt2) has been implicated in the mediation and regulation of angiogenesis and inflammation which are believed to be critical mechanisms in the pathogenesis of both abdominal aortic aneurysm (AAA) and cardiovascular events. | 22483260 |
| Cessation of life, Inflammation | Altered Intercellular Communication | Given that the literature suggests a strong link between social relationships and mortality, and that inflammation plays an important role in the leading causes of death, we had expected to find consistent and moderately strong associations between social relationships and inflammatory markers. | 22483707 |
| Tolosa-Hunt Syndrome, Inflammation, Methylated spirit | Altered Intercellular Communication | Tolosa-Hunt syndrome (THS), a nonspecific chronic inflammation of the cavernous sinus, is a rarely needed surgical manipulation, even for diagnosis, because corticosteroid therapy is markedly effective against this condition. | 22484067 |
| Inflammatory abnormality of the eye, diabetic | Altered Intercellular Communication | Patients with ocular inflammation followed at 5 United States tertiary centers that initially were neither diabetic nor taking hypoglycemic medications. | 22484116 |
| Inflammatory abnormality of the eye | Altered Intercellular Communication | These results suggest that the absolute risk of corticosteroid-induced hyperglycemia that is detected and treated with hypoglycemic therapy in the tertiary ocular inflammation setting is low (an excess cumulative risk on the order of 1% within 1 year), although on a relative scale it is approximately 4.4-fold higher than in patients not treated with oral corticosteroids. | 22484116 |
| Intraocular inflammation | Altered Intercellular Communication | Optical coherence tomography (OCT) revealed a CMO with a central thickness of 561 mm OD and 488 mm OS; there were no signs of intraocular inflammation. | 22484725 |
| Choroiditis | Altered Intercellular Communication | In order to understand the properties of taxane drug-induced cystoid macular oedema (TDICMO) we compared the spectral OCT findings of our case to an inflammation-induced CMO of equal thickness and to a case of multifocal choroiditis. | 22484725 |
| Choroiditis | Altered Intercellular Communication | In contrast to inflammation-induced CMO where the four external bands were well identified, there was attenuation of these bands in TDICMO but no disruption of the layers as seen in multifocal choroiditis, indicating that the fluid in TDICMO had a high viscosity producing a shadow underneath. | 22484725 |
| Inflammation, Tumor necrosis, Inflammatory abnormality of the eye | Altered Intercellular Communication | Several soluble mediators of inflammation such as tumor necrosis factor alpha (TNF-a) have been implicated in the pathogenesis of ocular inflammation. | 22484726 |
| Carcinoma, Chronic inflammation | Altered Intercellular Communication | Although the colonoscopic examination was highly suggestive of a carcinoma, the histopathological examinations were consistent with chronic inflammation. | 22486169 |
| Inflammation, Ulcerative Colitis | Altered Intercellular Communication | Cytokines from different T helper (Th) cell subsets are elevated in inflamed mucosa of patients with ulcerative colitis (UC), contributing to the inflammation. | 22486187 |
| Inflammation | Altered Intercellular Communication | Effector memory T-helper (Th)17 (Th17(EM)) cells are thought to be essential for inflammation in Th17-mediated diseases, but have not been studied in detail. | 22486269 |
| Crohn Disease, Gastrointestinal inflammation | Altered Intercellular Communication | Such upper gastrointestinal inflammation appears to be particularly common in patients with Crohn's disease. | 22486730 |
| Diabetes Mellitus, Non-Insulin-Dependent | Altered Intercellular Communication | T2D nonnephrotic patients with glomerular filtration rate (GFR) >30 ml/min and without acute cardiovascular/inflammatory conditions were included. | 22486808 |
| Granuloma, Inflammation, Thick, Ulcerative Colitis | Altered Intercellular Communication | Human CD tissues typically exhibited destructive full thickness enteritis with severe lympho-plasma infiltration and scattered additional granulomas; UC lesions exhibited much less inflammation than CD lesions. | 22486997 |
| Inflammation, Appendix Perforation, CTCAE | Altered Intercellular Communication | Histolopathologic examination confirmed appendiceal perforation with focal inflammation secondary to a foreign body. | 22487649 |
| Inflammation, Sleep Apnea, CTCAE, Endothelial dysfunction, Cerebrovascular accident | Altered Intercellular Communication | Biomarkers of inflammation and endothelial dysfunction in stroke with and without sleep apnea. | 22488018 |
| Inflammatory Bowel Diseases, Crohn Disease, Ulcerative Colitis | Altered Intercellular Communication | The inflammatory bowel diseases (IBD), Crohn's disease (CD), and ulcerative colitis (UC), are chronic inflammatory conditions of the gastrointestinal tract whose pathogenesis is not completely understood. | 22488632 |
| Inflammation, Fibrosis Assessment, Fatty degeneration | Altered Intercellular Communication | Neither steatosis nor inflammation had significant influence on HVRI-based estimation of fibrosis (1.45 +- 0.2; 1.26 +- 0.05; 1.06 +- 0.06; 0.87 +- 0.08; 0.46 +- 0.11 for F0-FIV, respectively). | 22488634 |
| Inflammation, Phlebitis of portal vein, Appendicitis, CTCAE, Diverticulitis, Phlebitis | Altered Intercellular Communication | Pylephlebitis is a very rare and dangerous complication of inflammatory abdominal processes, mainly appendicitis (1) and diverticulitis (2).We describe a case of peridiverticular inflammation leading to a extensive phlebitis of the adjacent sigmoid vein, extending to the inferior mesenteric vein up to the proximal portal vein, with distal embolus into the left portal vein. | 22489402 |
| ARCN1 gene, Inflammation, Chronic Obstructive Airway Disease, Systemic disease | Altered Intercellular Communication | Chronic obstructive pulmonary disease (COPD) is a complex systemic disorder characterized by both local pulmonary and systemic inflammation. | 22489883 |
| Ocular Hypertension, Inflammation | Altered Intercellular Communication | Benzalkonium chloride induces anterior chamber inflammation in previously untreated patients with ocular hypertension as measured by flare meter: a randomized clinical trial. | 22489894 |
| ARCN1 gene, Inflammation, Chronic Obstructive Airway Disease | Altered Intercellular Communication | Fibrinogen is a marker of systemic inflammation and may represent an important biomarker for the progression of chronic obstructive pulmonary disease (COPD). | 22489912 |
| Inflammation, Dental Plaque, Endothelial dysfunction, Atherosclerosis | Altered Intercellular Communication | An accepted hypothesis states that coronary atherosclerosis (CA) is initiated by endothelial dysfunction due to inflammation and high levels of LDL-C, followed by deposition of lipids and macrophages from the luminal blood into the arterial intima, resulting in plaque formation. | 22490844 |
| Inflammation, Atherosclerosis | Altered Intercellular Communication | According to this alternative proposal, coronary atherosclerosis is not related to inflammation and can occur in individuals with normal circulating levels of LDL, consistent with research findings. | 22490844 |
| Corneal endotheliitis, Inflammation | Altered Intercellular Communication | Corneal endotheliitis was not only the inflammation of endothelium, but also varied pathological changes of all layer of the cornea. | 22490910 |
| Diffuse Axonal Injury, Inflammation, Neuronal loss in central nervous system, Glycoproteins, Kearns-Sayre syndrome | Altered Intercellular Communication | Myelin-associated glycoprotein loss in Kearns-Sayre syndrome was associated with oligodendrocyte loss and nuclear translocation of apoptosis-inducing factor, whereas inflammation, neuronal loss, and axonal injury were minimal. | 22491194 |
| Central nervous system demyelination, Inflammation | Altered Intercellular Communication | Primary mitochondrial respiratory chain defects affecting the white matter, and unrelated to inflammation, are associated with MAG loss and central nervous system demyelination. | 22491194 |
| Inflammation, Edema, Chronic iridocyclitis | Altered Intercellular Communication | To investigate the adverse ocular effects of intravitreal ketorolac (4 mg) in patients with chronic uveitis and complications of chronic inflammation (macular edema). | 22491916 |
| Inflammation, septic | Altered Intercellular Communication | Septic patients with systemic inflammation and enhanced thrombin generation (n=60) exhibited increased MMP-10 and soluble CD40L levels associated with adverse clinical outcome. | 22492089 |
| Degenerative polyarthritis, Inflammation, Traumatic injury | Altered Intercellular Communication | Synovial inflammation, a feature of both osteoarthritis (OA) and meniscal injury, is hypothesized to be triggered in part via stimulation of Toll-like receptors (TLRs). | 22492243 |
| Inflammation | Altered Intercellular Communication | A 7-d consumption of red orange juice ameliorates endothelial function and reduces inflammation in nondiabetic subjects with increased cardiovascular risk. | 22492368 |
| Inflammation | Altered Intercellular Communication | However, during conditions of stress, such as inflammation, arginine availability can become limited, which may lead to a nonunion as a result of insufficient callus formation. | 22492379 |
| Inflammation | Altered Intercellular Communication | Although the overall contribution of this process to the underlying mechanisms for AS disease development remains unresolved, these observations suggest that modification of Sirt1 expression and/or activity could represent a novel approach against inflammation in AS. | 22493735 |
| Keratitis | Altered Intercellular Communication | Prolonged corneal inflammation associated with TSPK can cause visually significant scarring of the anterior corneal stroma. | 22495026 |
| Inflammation | Altered Intercellular Communication | The stronger associations in women suggest that sex differences might exist in the complex interplay between BP and inflammation. | 22495106 |
| Inflammation, Chronic heart failure | Altered Intercellular Communication | Such categories have been mainly designed by matching different molecules levels to different pathophysiological stages of chronic heart failure, and comprise biomarkers of inflammation, oxidative stress, extracellular-matrix remodeling, neurohormones, myocte injury and stress, with an additional group of new biomarkers not yet fully characterized. | 22495170 |
| Inflammation, Chronic heart failure | Altered Intercellular Communication | Such categories have been mainly designed by matching different molecules levels to different pathophysiological stages of chronic heart failure, and comprise biomarkers of inflammation, oxidative stress, extracellular-matrix remodeling, neurohormones, myocte injury and stress, with an additional group of new biomarkers not yet fully characterized. | 22495170 |
| Inflammation, Chronic disease | Altered Intercellular Communication | We also hypothesized an association of MPO with markers of other chronic diseases involving inflammation. | 22495256 |
| Inflammation, Myocardial Ischemia | Altered Intercellular Communication | However, the results support the third hypothesis and previously reported view that MPO is a marker of inflammation in patients of ischemic heart disease. | 22495256 |
| Inflammation, Atherosclerosis | Altered Intercellular Communication | Inflammation is critical for atherosclerosis development and may be a target for risk-reduction therapy. | 22496207 |
| Inflammation | Altered Intercellular Communication | The presence of low-grade inflammation and absence of positive affect, rather than presence of negative affect, may be important determinants of subjective health. | 22496462 |
| Airway structure, Allergy - Charge Type Reason | Altered Intercellular Communication | A very significant finding was that most allergy sufferers may have lower airway inflammation. | 22496703 |
| Airway structure | Altered Intercellular Communication | A better diagnosis of lower airway inflammation could be substantial in the management of these patients. | 22496703 |
| Inflammation, Endothelial dysfunction, diabetic, Atherosclerosis | Altered Intercellular Communication | Endothelial dysfunction is a common feature in type-2 diabetic patients and is associated with inflammation, increased levels of circulating soluble adhesion molecules and atherosclerosis. | 22497223 |
| Inflammation, Cachexia | Altered Intercellular Communication | Nearly all forms of cachexia are closely associated with chronic inflammation and elevated levels of inflammatory and pro-inflammatory circulating factors, including C-reactive protein (CRP), which is considered a valid laboratory and clinical marker. | 22497530 |
| ARCN1 gene, Chronic Obstructive Airway Disease | Altered Intercellular Communication | Chronic obstructive pulmonary disease (COPD) is characterized by inflammation of lung parenchyma and pulmonary hypoxemia with a proven systemic component. | 22497562 |
| Kidney Failure, Chronic, Fibrosis Assessment, Hepatitis C, Hepatitis | Altered Intercellular Communication | We compared the degree of liver inflammation and fibrosis in AA and CA patients with HCV infection, with and without ESRD. | 22497817 |
| Inflammation, Fibrosis Assessment | Altered Intercellular Communication | Specimens were graded for inflammation and fibrosis using Knodell histological activity index. | 22497817 |
| Renal Insufficiency, Fibrosis Assessment | Altered Intercellular Communication | Patients with renal impairment had lower mean serum transaminases, a higher mean serum alkaline phosphatase levels (all P < 0.0001) and less hepatic necro-inflammation (Knodell histological activity index -I, II and III; P < 0.05) and fibrosis (Knodell histological activity index -IV; P < 0.0001). | 22497817 |
| Kidney Failure, Chronic, Fibrosis Assessment, Hepatic inflammation, Kidney Diseases | Altered Intercellular Communication | Thus, HCV patients with ESRD had a lower degree of hepatic inflammation and fibrosis compared to those without renal disease, independent of race. | 22497817 |
| APP gene, Aortic Aneurysm, Abdominal, Acute and chronic inflammation | Altered Intercellular Communication | Abdominal aortic aneurysm (AAA) is associated with chronic mural inflammation and a pro-thrombotic diathesis. | 22497884 |
| Inflammation | Altered Intercellular Communication | Cytology of the biopsy demonstrated benign T-lymphocytes and histiocytes suggestive of mild chronic inflammation only. | 22498134 |
| Inflammation | Altered Intercellular Communication | Clinical evaluation of disease activity is often difficult, because most patients develop recurrent inflammation while receiving corticosteroid treatment. | 22498333 |
| Inflammation | Altered Intercellular Communication | FDG-PET/CT is useful for detection of active inflammation not only in patients with active TA before treatment but also in relapsing patients receiving immunosuppressive agents. | 22498333 |
| Inflammation, Fibrosis Assessment | Altered Intercellular Communication | Overall, loss of reticulin is more common and more extensive with marked fatty change and does not seem to be linked to inflammation or fibrosis stage. | 22498821 |
| Inflammation, Hemorrhage, Pancreatic Pseudocyst | Altered Intercellular Communication | The predominant histologic features were those of pancreatic pseudocyst, including a fibrotic cyst wall lacking epithelium and instead composed of myofibroblastic proliferation, hemorrhage, and inflammation. | 22498822 |
| Inflammation, Diabetes Mellitus, Non-Insulin-Dependent | Altered Intercellular Communication | T2D is primarily characterized by insulin resistance, and growing evidence has indicated the causative link between adipose tissue inflammation and the development of insulin resistance. | 22499789 |
| Inflammation | Altered Intercellular Communication | CD44 likely plays a causative role in the development of adipose tissue inflammation and insulin resistance in rodents and humans. | 22499789 |
| Plaque, Atherosclerotic | Altered Intercellular Communication | Evidence supporting a key role of Lp-PLA2-generated lysophosphatidylcholine in human atherosclerotic plaque inflammation. | 22499993 |
| Inflammation, atherosclerotic | Altered Intercellular Communication | To determine whether the level of lysophosphatidylcholine (lysoPC) generated by lipoprotein-associated phospholipase A2 (Lp-PLA2) is associated with severity of inflammation in human atherosclerotic plaques. | 22499993 |
| Inflammation | Altered Intercellular Communication | According to in vitro studies, lysoPCs are proinflammatory but the association between their generation and plaque inflammation remains unknown. | 22499993 |
| Inflammation | Altered Intercellular Communication | The associations among Lp-PLA2, lysoPCs, LPA, and proinflammatory cytokines in human plaques suggest that lysoPCs play a key role in plaque inflammation and vulnerability. | 22499993 |
| ARCN1 gene, Inflammation | Altered Intercellular Communication | Effect of incremental exercise on airway and systemic inflammation in patients with COPD. | 22500008 |
| ARCN1 gene, Inflammation, Chronic Obstructive Airway Disease | Altered Intercellular Communication | Airway and systemic inflammation are features of chronic obstructive pulmonary disease (COPD), and there is growing interest in clarifying the inflammatory processes. | 22500008 |
| Inflammation | Altered Intercellular Communication | A statistically significant improvement in visual acuity (p < 0.05) and a high statistically significant decrease of inflammation of the worst affected eyes (p = 0.001) were detected. | 22500372 |
| HD Term Type, Inflammation, Cachexia | Altered Intercellular Communication | Patients on HD with a BMI lower than 23 kg/m2 did not present signs of energy wasting, whereas those with a BMI higher than 23 kg/m2 had more inflammation, probably because of a greater adiposity. | 22503532 |
| Inflammation, Chronic Kidney Diseases | Altered Intercellular Communication | The inflammatory system is implicated in every stage of chronic kidney disease, and we hypothesized an additional value of markers of systemic inflammation in predicting response after renal artery stenting. | 22503569 |
| Hyperglycemia, Inflammation | Altered Intercellular Communication | In midlife, however, it was related to abdominal adiposity in addition to general adiposity, fasting hyperglycemia, higher HbA1c and subtle systemic inflammation. | 22504289 |
| Inflammation, Neoplasms | Altered Intercellular Communication | Several evidences have been published linking polymorphism in genes involved in chronic or recurrent inflammation with increased tumor risk and progression. | 22504414 |
| Inflammation | Altered Intercellular Communication | Moreover, caution is particularly important in patients with preoperative evidence of inflammation. | 22504895 |
| Degenerative polyarthritis, Inflammation, Calcinosis | Altered Intercellular Communication | In OA, mitochondrial-associated signaling has been implicated in the molecular events leading to cartilage degradation, including oxidative stress, defective chondrocyte biosynthesis and growth responses, increased cytokine-induced chondrocyte inflammation and matrix catabolism, cartilage matrix calcification and increased chondrocyte apoptosis. | 22504941 |
| Trachoma | Altered Intercellular Communication | The unadjusted prevalence of trachoma inflammation-follicular (TF) in children aged 1-9 years was 70.5% (95% CI: 68.6-72.3). | 22506082 |
| Inflammation, Hypertrophy | Altered Intercellular Communication | Inflammation has been proposed to be an important causative factor in ligamentum flavum hypertrophy. | 22506718 |
| Inflammation, Dental Plaque | Altered Intercellular Communication | Plaque and gingival inflammation were highly correlated with this condition, while demographic characteristics and drug dosage did not relate significantly. | 22506838 |
| Alcohol abuse | Altered Intercellular Communication | Chronic alcohol abuse and dependence are associated with dysfunctional dopaminergic neurotransmission in mesocorticolimbic circuits. | 22506971 |
| Crohn Disease | Altered Intercellular Communication | Metastatic Crohn's disease is a rare and complex inflammatory condition distinguished by cutaneous granulomatous lesions outside the gastrointestinal tract. | 22507210 |
| Inflammation, Rupture | Altered Intercellular Communication | Fourteen novel markers quantifying cardiomyocyte damage, inflammation and/or plaque rupture, and neurohormonal activation were measured at presentation. | 22507551 |
| Steatohepatitis, Fibrosis Assessment, Inflammation | Altered Intercellular Communication | Liver needle biopsy was performed in two of these subjects, confirming hepatic steatosis with minimal inflammation or fibrosis. | 22507979 |
| Diastolic dysfunction, Inflammation, Critical Illness | Altered Intercellular Communication | Severe inflammation leads to cardiac diastolic dysfunction, an independent prognostic marker for the mortality of critically ill patients. | 22508290 |
| Inflammation, Obesity | Altered Intercellular Communication | In obesity, adipose tissue becomes a significant source of chemokines and inflammatory cytokines that are associated with chronic systemic low-grade inflammation and may lead to insulin resistance. | 22508338 |
| Tubular adenoma, Papilloma, Intraductal Hyperplasia, Neoplasms | Altered Intercellular Communication | Among the 172 lesions, there were 66 (38%) fibroadenomas, 31 (18%) sclerosing adenoses, 24 (14%) fibrocystic changes, 16 (9%) mastitis/inflammations, 9 (5.5%) intraductal papillomas, 8 (5%) focal fibroses, 4 (2.5%) atypical ductal hyperplasias, 4 (2.5%) fat necroses, 2 (1%) phyllodes tumors, 1 (0.5%) tubular adenomas, 1 (0.5%) epidermal inclusion cysts, and 6 (3.5%) "other benign lesions." | 22508447 |
| Inflammation, Ulceration, CTCAE | Altered Intercellular Communication | The presence of extracellular and intracellular crystalline iron in the airway lumen and/or mucosa with associated varying degrees of ulceration and inflammation confirms the diagnosis. | 22508539 |
| Inflammation | Altered Intercellular Communication | Filarial lymphatic pathology is of multifactorial origin, with inflammation, lymphangiogenesis, and innate immune responses all playing important roles. | 22508858 |
| Inflammation, Obesity, Diabetes Mellitus | Altered Intercellular Communication | Chronic inflammation is now thought to play a key pathogenetic role in the associations of obesity with insulin resistance and diabetes. | 22509446 |
| Inflammation, Obesity, Diabetes Mellitus | Altered Intercellular Communication | Based on our recent findings on persistent organic pollutants (POPs) including the lack of an association between obesity and either insulin resistance or diabetes prevalence among subjects with very low concentrations of POPs, we hypothesized that POP concentrations may be associated with inflammation and modify the associations between inflammation and insulin resistance in non-diabetic subjects. | 22509446 |
| Inflammation, Eye pain | Altered Intercellular Communication | [Phase III open-label study of nepafenac ophthalmic suspension 0.1% for inflammation and ocular pain following ophthalmic surgery]. | 22509696 |
| Cataract, Eye pain, Acute inflammation | Altered Intercellular Communication | To examine the efficacy and safety of nepafenac ophthalmic suspension 0.1% on postoperative inflammation and eye pain with intraocular surgery, other than cataract surgery. | 22509696 |
| Cataract, Eye pain, Acute inflammation | Altered Intercellular Communication | Nepafenac ophthalmic suspension 0.1% is considered safe and efficious not only following cataract surgery but also for postoperative inflammation and eye pain in intraocular surgery. | 22509696 |
| Carcinoma of lung, Pneumonia, Interstitial, Pulmonary Emphysema | Altered Intercellular Communication | We therefore investigated associations between SFTPD variations and lung cancer as well as emphysema and interstitial pneumonia, which are characterized by chronic inflammation from which lung cancer often arises. | 22509983 |
| Fibrosis Assessment, Dacryoadenitis | Altered Intercellular Communication | Here are 23 lesions of idiopathic lacrimal gland inflammation collected retrospectively, whose histopathologic types were classified based on different characteristics, while the fibrosis degrees were measured. | 22510006 |
| Inflammation | Altered Intercellular Communication | Blinded histologic evaluation revealed a trend toward normal elastic fiber appearance (P = 0.255), increased wound complications (P = 0.546), and mild inflammation (P = 0.462) in the surgical group. | 22510895 |
| Inflammation, Colorectal Carcinoma | Altered Intercellular Communication | Our findings support the conclusion that adipokines involved in inflammation are associated with colorectal cancer risk, but that their effects may be mediated mostly by insulin, with leptin exerting an independent effect. | 22511581 |
| Anorexia Nervosa, Congenital Abnormality | Altered Intercellular Communication | Structural brain abnormalities in adolescent anorexia nervosa before and after weight recovery and associated hormonal changes. | 22511729 |
| Parotitis, Inflammation | Altered Intercellular Communication | Recurrent parotitis is an acute, severe inflammation of one or both parotid glands, the major salivary glands in young children. | 22512231 |
| Arterial Stiffness, Inflammation, Diabetes Mellitus, Non-Insulin-Dependent | Altered Intercellular Communication | The effect of sitagliptin versus glibenclamide on arterial stiffness, blood pressure, lipids, and inflammation in type 2 diabetes mellitus patients. | 22512265 |
| Mycobacterium Infections, Asthma, Respiratory Hypersensitivity, Inflammation | Altered Intercellular Communication | BCG and other mycobacterial infections suppress airway hyper-responsiveness and inflammation in asthma models; however, its efficacy in human populations remains controversial. | 22512632 |
| Communicable Diseases, Chlamydia, Inflammation, Chronic disease of respiratory system | Altered Intercellular Communication | The current study sought to determine if infection with Chlamydia triggers the production of pathogen-specific IgE in children with chronic respiratory diseases which might contribute to inflammation and pathology. | 22512977 |
| Reactive airway disease, Chlamydia, allergic inflammation, Asthma | Altered Intercellular Communication | IgE antibodies play a central role in allergic inflammation; therefore production of Chlamydia-specific IgE may prove significant in the exacerbation of chronic, allergic airway diseases, thus highlighting a direct role for Chlamydia in asthma pathogenesis. | 22512977 |
| Inflammation, Squamous cell carcinoma | Altered Intercellular Communication | In other centers, she had undergone previous biopsies, the results of which were suggestive of squamous cell carcinoma and aspecific inflammation. | 22513067 |
| Inflammation | Altered Intercellular Communication | Transforming growth factor-beta1 (TGF-beta1) is a pleiotropic cytokine that plays important roles in immunity and inflammation. | 22513132 |
| Autoimmune Diseases, glycation, Inflammation | Altered Intercellular Communication | Interaction of advanced glycation end products (AGEs) with their receptors (RAGE) plays an important role in inflammation in auto-immune diseases. | 22513366 |
| Inflammation, Virus Diseases | Altered Intercellular Communication | Neutralization of Pellino-1 may therefore provide opportunities to inhibit potentially harmful neutrophilic inflammation of the airways induced by respiratory viruses, without loss of control of the underlying viral infection. | 22514342 |
| Chronic lymphocytic inflammation, Alopecia, CTCAE, Scleroderma | Altered Intercellular Communication | To our knowledge, this is the first report of alopecia with perineural lymphocytic inflammation as a presenting sign of linear scleroderma en coup de sabre. | 22515223 |
| Inflammation, Primary malignant neoplasm | Altered Intercellular Communication | Inflammation and cancer: chemical approaches to mechanisms, imaging, and treatment. | 22515568 |
| Inflammation, Primary malignant neoplasm, Multiple Chronic Conditions, Cardiovascular Diseases | Altered Intercellular Communication | Chronic inflammation contributes to the etiology of multiple diseases, especially those associated with aging, such as cancer and cardiovascular disease. | 22515568 |
| Inflammation, Primary malignant neoplasm | Altered Intercellular Communication | The current perspective summarizes our research on unsaturated fatty acid oxidation in the context of inflammation and cancer. | 22515568 |
| Alopecia Areata, Alopecia | Altered Intercellular Communication | Alopecia areata (AA) is a chronic inflammatory condition characterized by hair loss, most frequently from the scalp. | 22515582 |
| Vasculitis, Leukocytoclastic, Cutaneous, Inflammation | Altered Intercellular Communication | Cutaneous leukocytoclastic vasculitis (CLV) is a necrotizing inflammation of the small vessels in the dermis. | 22515974 |
| Inflammation, Coronary artery | Altered Intercellular Communication | The noninvasive assessment of coronary artery plaque biology would be a major advance particularly in the identification of vulnerable plaques, which are associated with specific pathological characteristics, including micro-calcification and inflammation. | 22516444 |
| Inflammation, Aortic Valve Stenosis | Altered Intercellular Communication | (An Observational PET/CT Study Examining the Role of Active Valvular Calcification and Inflammation in Patients With Aortic Stenosis; NCT01358513). | 22516444 |
| Inflammation, Fibrosis Assessment | Altered Intercellular Communication | We will review the relative strengths and limitations of MRE as applied to clinical evaluation and therapeutic decisions, including the use of the unique capacity to delineate active inflammation and fibrosis in the submucosal and deeper enteric tissues, which is beyond the diagnostic reach of endoscopy and biopsy. | 22517074 |
| Intraocular inflammation, PDR gene, Retinal Diseases | Altered Intercellular Communication | Intraocular inflammation seems to be involved in PDR but does not seem to be prominent in early retinopathy stages, i.e. | 22520269 |
| Gastroesophageal reflux disease, Inflammation, Helicobacter pylori | Altered Intercellular Communication | Although gastroesophageal reflux disease and Helicobacter pylori are both associated with chronic inflammation of the adjacent cardia mucosa, it is not known whether these lead to derangements of the desmosomal complexes. | 22521077 |
| Inflammation | Altered Intercellular Communication | Nasal irrigations are often mentioned as measures for treating sinonasal inflammations. | 22521235 |
| Inflammation, Sleep Apnea, Obstructive, Osage language | Altered Intercellular Communication | Obstructive sleep apnea (OSA) has been associated with chronic inflammation. | 22521311 |
| Steatohepatitis, Fibrosis Assessment, Non-alcoholic Fatty Liver Disease, Inflammation | Altered Intercellular Communication | Visceral adiposity is associated with hepatic steatosis, inflammation, and fibrosis in non-alcoholic fatty liver disease (NAFLD). | 22521350 |
| Inflammation, Fibrosis Assessment, Fatty degeneration | Altered Intercellular Communication | VAI was not associated with steatosis, lobular inflammation or fibrosis, but WC was associated with fibrosis (p=0.01). | 22521350 |
| Inflammation, Fibrosis Assessment, Non-alcoholic Fatty Liver Disease, Fatty degeneration | Altered Intercellular Communication | In NAFLD, VAI is not associated with steatosis, inflammation or fibrosis. | 22521350 |
| Endocrine System Diseases, Traumatic injury | Altered Intercellular Communication | It may also result from injurious processes including frostbite, physical trauma, inflammatory conditions, and various endocrinopathies. | 22522358 |
| REM Sleep Behavior Disorder, palladium, RNA Recognition Motif, Parkinson Disease | Altered Intercellular Communication | Rapid eye movement sleep behavior disorder (RBD) is common in Parkinson disease (PD), but its relationship to the varied neurotransmitter deficits of PD and prognostic significance remain incompletely understood. | 22522445 |
| Inflammation | Altered Intercellular Communication | Combined significant (2+ or 3+) acute and chronic inflammation had a specificity of 98% and a negative predictive value of 97%. | 22523211 |
| Hematoxylin and eosin stain method, Inflammation | Altered Intercellular Communication | Our results show that, in our institution, HP can be seen relatively easily with H&E staining in the majority of cases; however, a small number of cases with significant inflammation can be missed if stains are not used. | 22523211 |
| Neoplasms | Altered Intercellular Communication | The interplay between p53 and p73 and HPV16 may lead to deregulation of cell cycle and apoptosis, through which inflammation/immune responses control the HPV clearance and escape of immune surveillance, and subsequently contribute to tumor HPV16 status. | 22523600 |
| Inflammation, Migraine Disorders, Atherosclerosis | Altered Intercellular Communication | There is a relationship between atherosclerosis and inflammation in migraine patients. | 22524899 |
| Inflammation, Hypertension, CTCAE, Obesity | Altered Intercellular Communication | Obesity and hypertension are associated with an adverse metabolic profile and systemic low-grade inflammation. | 22525206 |
| Lymphoid hyperplasia, Thyroid associated opthalmopathies, Parasitic Diseases, Eosinophilic granulomatosis with polyangiitis, Ocular Adnexal Lymphoma, Blepharitis, Granulomatosis with polyangiitis, Orbital Pseudotumor, "Sjogrens Syndrome | Altered Intercellular Communication | The differential diagnosis extends to thyroid eye disease; blepharitis; Sjogren's syndrome; Churg-Strauss vasculitis; Wegener's granulomatosis; Gleich syndrome; orbital and ocular lymphoid hyperplasia or adnexal lymphoma; idiopathic orbital inflammatory disease/idiopathic sclerosing orbital inflammation; rarely, orbital parasitosis; and IgG4-related diseases. | 22525399 |
| Inflammation, Pre-Eclampsia | Altered Intercellular Communication | Preeclampsia may be due to an excess of circulating anti-angiogenic growth factors derived from the placenta, but metabolic syndrome-like disorders may also set off a cascade of placental and systemic inflammation and oxidative stress. | 22525475 |
| Inflammation, Fibrosis Assessment | Altered Intercellular Communication | The differences between groups were compared by calculating the ratio of inflammation above G2 or fibrosis staging above S2. | 22525497 |
| Inflammation, Fibrosis Assessment | Altered Intercellular Communication | The percentages of the chronic HBV carriers with liver histopathology inflammation graded above G2 or fibrosis staging above S2 were 26.5% (36/136) in 11 to 29 year-old group, 39.4% (37/94) in 30-39 year-old group and 58.1% (36/62) in 40-60 year-old group. | 22525497 |
| Inflammation, Fibrosis Assessment | Altered Intercellular Communication | 39.4% (37/94) of chronic HBV carriers were found with inflammation graded above G2 or fibrosis staging above S2 in 30-39 year-old group, no statistically significant difference found between group 30-39 years old and group and 40-60 years old 58.1% (36/62) (P less than 0.01). | 22525497 |
| Inflammation, Fibrosis Assessment | Altered Intercellular Communication | 26.5% (36/136) of chronic HBV carriers under 30 years old were with inflammation graded above G2 or fibrosis staging above S2 as compared with the percentage of 46.8% (73/156) in the chronic HBV carriers over 30 years old group, and significant difference existed between the two groups (P less than 0.01). | 22525497 |
| Malignant tumor of extrahepatic bile duct, Inflammation | Altered Intercellular Communication | The significance of the presence of preoperative inflammation for the prognosis of patients with extrahepatic bile duct cancer (BDCA) was evaluated. | 22526039 |
| Inflammation, In-Stent Restenosis Indicator | Altered Intercellular Communication | Chronic continuous inflammation plays an important role after implantation of both types of stent with regard to in-stent restenosis in patients on hemodialysis. | 22526379 |
| Inflammation, Fracture | Altered Intercellular Communication | Low-grade inflammation, assessed by serum high-sensitivity C-reactive protein (hsCRP) concentration, is associated with higher fracture risk irrespective of areal bone mineral density (aBMD). | 22527204 |
| Noncommunicable Diseases, Inflammatory abnormality of the eye | Altered Intercellular Communication | Forty ocular samples from non-infectious patients without ocular inflammation were collected as controls. | 22527320 |
| Inflammation | Altered Intercellular Communication | However gut flora changes, inflammation and neuro-glial injury have been implicated. | 22527995 |
| helium, Inflammation | Altered Intercellular Communication | The correlation network showed Prevotella to be linked to improved cognition and decreased inflammation in patients without HE recurrence. | 22527995 |
| Inflammation, Hypoalbuminemia | Altered Intercellular Communication | Relative contributions of inflammation and inadequate protein intake to hypoalbuminemia in patients on maintenance hemodialysis. | 22528583 |
| Inflammation, Hypoalbuminemia | Altered Intercellular Communication | We hypothesize that these inadequate protein intake and inflammation contribute somewhat equally to hypoalbuminemia. | 22528583 |
| Idiopathic Inflammatory Myopathies, Atrophic, Myositis | Altered Intercellular Communication | Use of this strategy may prove useful in the study of idiopathic inflammatory myopathy and other diseases characterized by both muscle inflammation and atrophy. | 22528929 |
| Inflammation, Dental Plaque, Atherosclerosis | Altered Intercellular Communication | Inflammation and adaptive immunity modulate atherosclerosis and plaque instability. | 22529217 |
| Inflammation, mitral annulus calcification | Altered Intercellular Communication | Association of mitral annulus calcification with high-sensitivity C-reactive protein, which is a marker of inflammation. | 22529527 |
| Inflammation, Premature calcification of mitral annulus, MARCKS wt Allele | Altered Intercellular Communication | There are limited clinical data revealing the relationship between mitral annular calcification (MAC) and systemic inflammation. | 22529527 |
| Inflammation, MARCKS wt Allele | Altered Intercellular Communication | Our study demonstrated that hs-CRP, which is a sensitive marker of systemic inflammation, increased in patients with MAC. | 22529527 |
| Inflammation, Hematuria, CTCAE | Altered Intercellular Communication | Inflammation, hematuria and smoking did not confound the results. | 22530010 |
| Inflammation | Altered Intercellular Communication | One important finding is that survivin was not influenced by confounders like inflammation and exhibited a relatively low number of false-positives. | 22530010 |
| Inflammation, Crohn Disease | Altered Intercellular Communication | This aspect was not suggestive of an active inflammation such as Crohn's disease, where a marked contrast medium enhancement should be expected. | 22530462 |
| Inflammation, Liver diseases, Chronic liver disease, Lymphoproliferative Disorder of the Skin | Altered Intercellular Communication | Based on the essential pathogenic role of inflammation for progression of liver diseases, we hypothesized that sIL-2R might be an indicator of inflammatory cell activation and disease severity in patients with chronic liver diseases (CLD). | 22530792 |
| Inflammation, Kidney Failure, Liver Dysfunction | Altered Intercellular Communication | In addition, renal failure was an important confounder of sIL-2R levels independent of liver dysfunction and inflammation. | 22530792 |
| Inflammation, Bipolar Disorder | Altered Intercellular Communication | Hypocortisolism may contribute to increased risk of depressive symptoms as a result of the loss of glucocorticoid attenuation of stress-induced inflammation. | 22531368 |
| Inflammation, Hyperintensity of cerebral white matter on MRI | Altered Intercellular Communication | White matter hyperintensities, systemic inflammation, brain growth, and cognitive functions in children exposed to air pollution. | 22531421 |
| Inflammation, Cognition Disorders, Nerve Degeneration | Altered Intercellular Communication | Identification of biomarkers associating systemic inflammation to brain growth is critical for detecting children at higher risk for cognitive deficits and neurodegeneration, thereby warranting early implementation of neuroprotective measures. | 22531421 |
| Inflammation | Altered Intercellular Communication | The regulated upon activation, normal T cell expressed and secreted (RANTES) production in psoriatic lesions may amplify the inflammation in these lesions. | 22531960 |
| Nasal inflammation, Congestion | Altered Intercellular Communication | Therefore, especially in the management of AR-related nasal inflammation and congestion, nGCSs are considered the most appropriate treatment. | 22532282 |
| allergic inflammation | Altered Intercellular Communication | This review will discuss the pathophysiology of allergic inflammation in the nasal mucosa and the mechanism of action of nGCSs; also the efficacy and safety of nGCSs will be discussed by focusing on clinical evidence. | 22532282 |
| Gingival Hyperplasia, Inflammation | Altered Intercellular Communication | Gingival enlargement and inflammation had completely disappeared after nonsurgical treatment for the maxilla and after surgical treatment for the mandible. | 22532949 |
| Inflammation | Altered Intercellular Communication | HIV status, burden of comorbid disease, and biomarkers of inflammation, altered coagulation, and monocyte activation. | 22534147 |
| Inflammation, HIV, Cyclophosphamide/Vincristine/Dacarbazine Regimen, Cardiovascular Diseases | Altered Intercellular Communication | Biomarkers of inflammation, altered coagulation, and monocyte activation are associated with mortality and cardiovascular disease (CVD) in the general population and among human immunodeficiency virus (HIV)-infected people. | 22534147 |
| Inflammation | Altered Intercellular Communication | These data suggest that ongoing HIV replication and immune depletion significantly contribute to increased prevalence of elevated biomarkers of inflammation, altered coagulation, and monocyte activation. | 22534147 |
| Inflammation | Altered Intercellular Communication | A link between androgen deficiency and fibrinolysis, protein synthesis deficiency, inflammation and trophicity is well documented in the literature. | 22534310 |
| Crohn Disease, Inflammation, Inflammatory disorder | Altered Intercellular Communication | Crohn's disease is a chronic transmural inflammatory disorder characterized by inflammation of the intestine. | 22534313 |
| Inflammation, Diabetes Mellitus, Insulin-Dependent | Altered Intercellular Communication | Urine a-Glutathione S-transferase, systemic inflammation and arterial function in juvenile type 1 diabetes. | 22534514 |
| Diabetes Mellitus, Insulin-Dependent, Inflammation, Vascular Diseases | Altered Intercellular Communication | To investigate in young patients with type 1 diabetes whether urine a-Glutathione S-transferase to creatinine ratio (a-GST:crea) relates to markers of systemic inflammation and subclinical vasculopathy. | 22534514 |
| Inflammation, Acute mediastinitis | Altered Intercellular Communication | Monitoring of biochemical markers of inflammation in acute mediastinitis (AM) can be useful in the modification of treatment. | 22534711 |
| Inflammation | Altered Intercellular Communication | The combination of the two processes can exacerbate inflammation, resulting in increases in both resistance to erythropoietin (EPO) and mortality. | 22535158 |
| Neurogenic Inflammation | Altered Intercellular Communication | These symptoms may be the cause of a phenomenon described in the literature as a neurogenic skin inflammation. | 22535604 |
| Inflammation, Hemochromatosis, Fatty Liver, Hyperferritinaemia, Malignant Neoplasms, HEMOCHROMATOSIS, TYPE 4, Juvenile-Onset Still Disease, Liver Cirrhosis | Altered Intercellular Communication | Even when inflammation, cirrhosis, Still's disease, fatty liver and malignancy are excluded, there remains a group of patients with unexplained hyperferritinaemia for whom rare forms of haemochromatosis (ferroportin disease) are a consideration. | 22535864 |
| Inflammation, Malnutrition | Altered Intercellular Communication | Malnutrition and chronic inflammation in dialysis patients negatively impacts prognosis. | 22536073 |
| Amyotrophic Lateral Sclerosis, Inflammation, Trauma, Nervous System | Altered Intercellular Communication | While free radicals and inflammation constitute major routes of neuronal injury occurring in amyotrophic lateral sclerosis (ALS), neither antioxidants nor non-steroidal anti-inflammatory drugs have shown significant efficacy in human clinical trials. | 22537108 |
| Amyotrophic Lateral Sclerosis, Inflammation | Altered Intercellular Communication | We examined the possibility that concurrent blockade of free radicals and prostaglandin E(2) (PGE(2))-mediated inflammation might constitute a safe and effective therapeutic approach to ALS. | 22537108 |
| Inflammation | Altered Intercellular Communication | Plasma CD40L, CXCL5, CCL5 and EGF are mainly platelet-derived, suggesting a role of platelets in immune responses and inflammation. | 22537155 |
| Acute Coronary Syndrome, Periodontitis, Inflammation, GDC AJCC Clinical Stage Terminology | Altered Intercellular Communication | An association exists between chronic infection-induced inflammation, such as periodontitis, and acute coronary syndrome (ACS). | 22537345 |
| Nonalcoholic Steatohepatitis, Inflammation, Hepatitis C | Altered Intercellular Communication | Circulating microparticles as disease-specific biomarkers of severity of inflammation in patients with hepatitis C or nonalcoholic steatohepatitis. | 22537612 |
| Carcinogenic Chlorinated Hydrocarbon, Inflammation, Hepatitis C, Chronic | Altered Intercellular Communication | Microparticles released into the bloodstream upon activation or apoptosis of CD4(+) and CD8(+) T cells correlate with inflammation as determined by histologic analysis in patients with chronic hepatitis C (CHC). | 22537612 |
| Carcinogenic Chlorinated Hydrocarbon, Fibrosis Assessment, Inflammation, Fatty Liver Disease | Altered Intercellular Communication | We compared profiles of circulating microparticles from patients with NAFL and NASH (n = 67) to those of CHC (n = 42), with healthy individuals (controls) using flow cytometry; the profiles were correlated with inflammation grade and fibrosis stage based on histologic analyses. | 22537612 |
| Inflammation, Fibrosis Assessment | Altered Intercellular Communication | We assessed the ability of the profiles to determine the severity of inflammation and fibrosis based on serologic and histologic analyses. | 22537612 |
| Chronic liver disease, Hepatic inflammation | Altered Intercellular Communication | Quantification of immune cell microparticles from serum samples can be used to assess the extent and characteristics of hepatic inflammation in patients with chronic liver disease. | 22537612 |
| Refractory anemias, Inflammation | Altered Intercellular Communication | In immunohistochemistry, inflammation induced by RA/CyD was more moderate than that induced by RA. | 22538278 |
| Fibrous, Inflammation | Altered Intercellular Communication | Some of the extracted adherent tissue consisted of hyalinized fibrous tissue that had the appearance of soft tissue which had organized because of inflammation. | 22538287 |
| Inflammation, Mucous Membrane | Altered Intercellular Communication | To evaluate developmental changes in mucosal inflammatory response, we used trinitrobenzene sulfonic acid (TNBS)-induced inflammation as a nonspecific insult and compared mucosal injury in newborn vs. adult mice. | 22538401 |
| Inflammation, Thrombosis | Altered Intercellular Communication | Deficiencies in the protein C (PC) pathway components not only promote thrombosis, but also exacerbate inflammation. | 22538795 |
| Inflammation, Lymphoma | Altered Intercellular Communication | The expressions of miR-21, miR-155 and miR-210 were assayed by RT-PCR in plasma of 54 cases of lymphoma, 10 cases of lymphonode inflammation and 27 cases of normal controls. | 22541087 |
| Inflammation, Lymphoma | Altered Intercellular Communication | The results indicated that the expressions of miR-21, miR-155 and miR-210 in plasma of lymphoma patients were higher than those of control group and lymphonode inflammation group (P < 0.05). | 22541087 |
| Inflammation, Gastritis, Infection caused by Helicobacter pylori | Altered Intercellular Communication | This study showed that CagA-positive H. pylori infection is associated with more severe gastritis and with increased bacterial density and inflammation in the biopsy specimens. | 22541262 |
| Inflammatory Bowel Diseases, Dysbiosis, Obesity, Hypersensitivity, Disease | Altered Intercellular Communication | Deviations from healthy microbial compositions (dysbiosis) have been linked with important human diseases, including inflammation-linked disorders, such as allergies, obesity, and inflammatory bowel disease. | 22541361 |
| Inflammation, Fibrosis Assessment | Altered Intercellular Communication | Histologic evidence of inflammation as well as degree of subepithelial fibrosis at presentation was compared with most recent biopsies while receiving PPI therapy. | 22541409 |
| Inflammation, "Extra-osseous Ewings sarcoma | Altered Intercellular Communication | Patients with EoE treated with PPIs show an improvement in symptoms and z-scores despite persistent eosinophilic inflammation. | 22541409 |
| Communicable Diseases, Inflammation, Traumatic injury | Altered Intercellular Communication | Patients underwent penetrating keratoplasty (PK) (n = 142, 39.2%), anterior lamellar keratoplasty (ALK) (n = 127, 35.1%), or a peripheral corneoscleral patch graft (n = 93, 25.7%) most commonly for inflammation (n = 68, 18.8%), trauma (n = 66, 18.2%), or infection (n = 66, 18.2%). | 22541633 |
| Keratitis | Altered Intercellular Communication | Active corneal inflammation (hazard ratio [HR], 2.5; 95% CI, 1.4-4.4; P = 0.003) and larger donor and recipient graft sizes of >= 9 mm (HR, 17.9; 95% CI, 2.3-140.3; P = 0.006) were risk factors for physiologic graft failure in anatomically successful eyes with central tectonic grafts. | 22541633 |
| Keratitis | Altered Intercellular Communication | For anatomically successful cases with central tectonic grafts, active corneal inflammation and donor size >= 9 mm were risk factors for physiologic failure. | 22541633 |
| Inflammation, Myocardial Ischemia | Altered Intercellular Communication | Low-level exposure to ambient particulate matter is associated with systemic inflammation in ischemic heart disease patients. | 22541720 |
| Inflammatory abnormality of the eye, Uveitis | Altered Intercellular Communication | In most eyes with uveitis and ERM, VA remains stable if ocular inflammation and comorbidities are addressed appropriately. | 22541930 |
| Tissue Factor-Derived Microparticle, Inflammation | Altered Intercellular Communication | Although there was a statistically significant decrease in TFMP, this decrease did not correlate with changes in markers of thrombin generation or inflammation. | 22542362 |
| Inflammation | Altered Intercellular Communication | In cardiac rehabilitation patients, particles were associated with subclinical decreases in parasympathetic modulation, prolongation of late repolarization duration, increased blood pressure, and systemic inflammation. | 22542955 |
| Associate of Engineering, Epiglottitis, Inflammation, Airway Obstruction | Altered Intercellular Communication | Acute epiglottitis (AE) is inflammation of the epiglottis and contiguous tissues, which carries a potential for complete airway obstruction. | 22543595 |
| Hepatitis, Hyperglycemia, Hypertriglyceridemia, Fatty degeneration, Obesity, Fibrosis, Liver | Altered Intercellular Communication | Obesity, hypertriglyceridemia, hyperglycemia, liver fibrosis, and liver inflammation were all independently associated with worse steatosis. | 22543885 |
| Inflammation, Fibrosis Assessment | Altered Intercellular Communication | Degrees of HS, iron deposition, inflammation, and fibrosis were analyzed in liver resection (n = 37) and biopsy (n = 19) specimens. | 22543969 |
| Inflammation | Altered Intercellular Communication | Nematode-induced low-grade chronic inflammation of the iris. | 22543998 |
| Metabolic Syndrome X, ETV3 wt Allele | Altered Intercellular Communication | The reported associations between metabolic syndrome (MetS) and systemic vascular inflammation/insulin resistance prompted the author to determine the predictive ability of markers for MetS in the occupational field. | 22544164 |
| Inflammation, Nerve Degeneration | Altered Intercellular Communication | Many of these genes are involved in inflammation regulation and neurodegeneration, e.g. | 22545106 |
| Inflammation | Altered Intercellular Communication | Over-expression of genes associated with inflammation (CD86, CD209, CLEC4, EGFR2, TFF3, among others) was observed in the CSP group. | 22545113 |
| Inflammation | Altered Intercellular Communication | When the analysis was restricted to ECD kidneys, genes involved in inflammation were also differentially up-regulated in ECD kidneys undergoing CSP. | 22545113 |
| TNF protein, human, Chagas Cardiomyopathy, Myocarditis | Altered Intercellular Communication | These results indicate that reduced production of the cytokines IL-10 and IL-17 in association with high levels of IFN-g and TNF-a is correlated with the severity of the Chagas' disease cardiomyopathy, and the immunological imbalance observed may be causally related with deficient suppressor activity of regulatory T cells that controls myocardial inflammation. | 22545173 |
| Inflammation | Altered Intercellular Communication | Punch biopsy of the skin lesion showed ulceration and dense dermal acute and chronic inflammation. | 22545328 |
| Inflammation, Traumatic injury | Altered Intercellular Communication | The patient denied any history of trauma, rubbing, insect bite, or inflammation at the site. | 22545327 |
| Inflammation, Necrosis | Altered Intercellular Communication | The first biopsies were inconclusive, showing only necrotic cells and purulent inflammation with epithelial elements. | 22545391 |
| Inflammation, Myocardial Infarction | Altered Intercellular Communication | [The reactants of acute phase of inflammation and anti-inflammatory cytokines under various complications of cardiac infarction]. | 22545471 |
| Inflammation | Altered Intercellular Communication | This is potentially associated with bacterial translocation from the gut leading to local and systemic inflammation. | 22545716 |
| Bacteremia, Inflammation, Endotoxemia, Peritonitis | Altered Intercellular Communication | Open appendectomy, in case of peritonitis, increased the incidence of bacteremia, endotoxemia, and systemic inflammation compared with laparoscopic appendectomy. | 22546132 |
| Sepsis, Inflammation | Altered Intercellular Communication | Early enhanced postoperative systemic inflammation may cause lower transient immunologic defense after laparotomy (decrease of HLA-DR), leading to enhanced sepsis in these patients. | 22546132 |
| Inflammation, "Alzheimers Disease", Periodontal Diseases, Data types - Address | Altered Intercellular Communication | Chronic inflammation in periodontal disease has been suggested as a potential risk factor in Alzheimer's disease (AD). | 22546352 |
| Inflammation, Chronic Obstructive Airway Disease, Premature aging syndrome | Altered Intercellular Communication | Chronic obstructive pulmonary disease/emphysema (COPD/emphysema) is characterized by chronic inflammation and premature lung aging. | 22546858 |
| Pulmonary Emphysema, Pneumonitis | Altered Intercellular Communication | Inhibition of lung inflammation by an NF-kB/IKK2 inhibitor did not have any beneficial effect on emphysema. | 22546858 |
| Inflammation, Pulmonary Emphysema | Altered Intercellular Communication | Thus, SIRT1 protects against emphysema through FOXO3-mediated reduction of cellular senescence, independently of inflammation. | 22546858 |
| Inflammation | Altered Intercellular Communication | Both acute and chronic blood glucose variability can induce oxidative stress and chronic inflammation. | 22547264 |
| Tumor necrosis, precancerous lesions, Pneumonitis | Altered Intercellular Communication | Some inflammatory factors, such as tumor necrosis factor, interleukin 1 and interleukin 6, were upregulated in lung tissue of transgenic mice compared with that of wild-type mice, implying that long-term HER2 overexpression could induce serious lung inflammation and some precancerous lesions. | 22547270 |
| Inflammation, Carcinogenesis | Altered Intercellular Communication | This model would be useful for studying the mechanism of HER2 involvement in lung carcinogenesis and for understanding the relationship between carcinogenesis and inflammation. | 22547270 |
| Inflammation, Diabetes Mellitus | Altered Intercellular Communication | Chronic low-grade inflammation is crucial for the development of insulin resistance and type 2 diabetes mellitus (T2DM), and immunocompetent cells, such as T-cells, B-cells, mast cells and macrophages, regulate the pathogenesis of T2DM. | 22547395 |
| Inflammation | Altered Intercellular Communication | Our data indicated that a higher frequency of activated NK cells may participate in the obesity-related chronic inflammation involved in the pathogenesis of T2DM. | 22547395 |
| Refractory anemias, Inflammation | Altered Intercellular Communication | However, whether Cyr61 in turn regulates Th17 cell differentiation and further enhances inflammation of RA remained unknown. | 22547695 |
| Fibrosis Assessment, Pneumonitis | Altered Intercellular Communication | Radiation alone induced acute pulmonary inflammation and lung fibrosis after 16 weeks associated with reduced life span. | 22547771 |
| Inflammation, Fibrosis Assessment | Altered Intercellular Communication | VCT, MRI, and histology showed that LY2109761 markedly reduced inflammation and pulmonary fibrosis resulting in prolonged survival. | 22547771 |
| Inflammation | Altered Intercellular Communication | The markers of inflammation secreted by the adipose tissue (adiponectin, leptin, resistin) showed significant differences in patients from the case group (with PAOD) compared to the control group. | 22547903 |
| Inflammation, Glucocorticoid deficiency with achalasia, Aortic Aneurysm, Abdominal | Altered Intercellular Communication | Inflammation plays a key role in the pathophysiology of abdominal aortic aneurysms (AAAs). | 22547907 |
| Inflammation, palladium, Communicable Diseases, Obesity, Dental Plaque | Altered Intercellular Communication | Plaque index, reflecting dental plaque, and PD, closely linked with periodontal inflammation and infection, are statistically associated with high BMI and obesity, independently of dietary patterns and insulin resistance. | 22548413 |
| Refractory anemias, Inflammation | Altered Intercellular Communication | We have previously reported that high levels of antibodies specific for native human type II collagen (anti-CII) at the time of RA diagnosis were associated with concurrent but not later signs of inflammation. | 22548748 |
| Refractory anemias, Inflammation | Altered Intercellular Communication | In contrast, anti-cyclic citrullinated peptide antibodies (anti-CCP) were associated both with late inflammation and late radiological destruction in the same RA cohort. | 22548748 |
| Rheumatoid Arthritis, Inflammation | Altered Intercellular Communication | Plasma asymmetric dimethylarginine in active rheumatoid arthritis: links with oxidative stress and inflammation. | 22549098 |
| Inflammation, Neck stiffness, Globus Sensation, Neck Pain | Altered Intercellular Communication | Prevertebral tendinitis should be considered when patients suffer from neck pain, neck stiffness, and globus sensations despite low signs of inflammation in the laboratory report. | 22549265 |
| Inflammation, Hemorrhage, Obesity, Abdominal, Fibrosis Assessment | Altered Intercellular Communication | Conversion to laparotomy was required for seven patients (35 %) due to bleeding (n = 1), Roux loop venous congestion (n = 1), abdominal obesity (n = 2), and severe fibrosis and inflammation around the cyst (n = 3). | 22549376 |
| Inflammation, Neoplasms, Diverticular Diseases | Altered Intercellular Communication | Bowel cleansing, polyps, angioectasias, diverticular disease, inflammation, and neoplasm were also verified. | 22549378 |
| Late Onset Disorders, Inflammation, Protein Glycosylation | Altered Intercellular Communication | Glycosylation aberrancy was comparable in patients with and those without antinuclear antibodies and in both early- and late-onset disease and exhibited at most a weak correlation with markers of inflammation. | 22549726 |
| Gingivitis, Periodontal Diseases, GDC AJCC Clinical Stage Terminology | Altered Intercellular Communication | Patients with ACS had more severe periodontal disease and higher levels of gingival inflammation than the control group (p < 0.001). | 22550814 |
| Inflammation, Periodontal Ligament | Altered Intercellular Communication | Appearance of antibodies to HSP plays a role in immune reactions, which maintain chronic inflammation of periodontium. | 22550879 |
| Inflammation, Atrial Fibrillation, Atrial Fibrillation by ECG Finding | Altered Intercellular Communication | Subclinical inflammation and atrial stretch have been recognized as important contributors to atrial fibrillation (AF) onset and perpetuation. | 22552174 |
| Inflammation, Drowning, Lung Injury, Hypothermia due to exposure | Altered Intercellular Communication | These observations suggest characteristic molecular biological patterns of pulmonary injury involving suppression of pulmonary surfactants and activation of early-phase mediators of inflammation in drowning, with high mRNA expression levels of pulmonary surfactants in fatal hypothermia; however, there was no significant difference among these markers in immunohistochemical detection, except for SP-A. | 22552475 |
| Inflammation, Cholestasis | Altered Intercellular Communication | In histological findings, bile duct proliferation and cholestasis predominated in the low group and portal inflammation predominated in the high group. | 22552497 |
| Inflammation, Exacerbation | Altered Intercellular Communication | [Etiology and biomarkers of systemic inflammation in mild to moderate COPD exacerbations]. | 22552550 |
| Inflammation, Exacerbation, Symptom aggravating factors | Altered Intercellular Communication | Compared to viral exacerbations, bacterial aggravations were associated with a systemic inflammation of higher magnitude. | 22552550 |
| Inflammation, Exacerbation | Altered Intercellular Communication | Biomarkers of systemic inflammation increase during mild to moderate COPD exacerbations. | 22552550 |
| Inflammation, Bacterial Infections, Exacerbation | Altered Intercellular Communication | The increase in systemic inflammation seems to be limited to exacerbations caused by bacterial infections. | 22552550 |
| Granulomatous inflammation | Altered Intercellular Communication | MALDI-IMS localized signals consistent with ESAT-6 only within sites of granulomatous inflammation, whereas P. acnes signals were distributed throughout the specimen. | 22552860 |
| Communicable Diseases, Inflammation | Altered Intercellular Communication | In the two investigated patients, there was no evidence of chronic HHV6 infection, minimal evidence of cerebral inflammation, and no significant improvement with pulse with intravenous methylprednisolone and immunoglobulin. | 22554258 |
| Inflammation, Disease | Altered Intercellular Communication | Low-grade inflammation in early childhood might protect from allergic diseases later in life. | 22554299 |
| Inflammation | Altered Intercellular Communication | However, our results suggest that the role played by the environmental factors in low-grade inflammation may differ between sensitized and non-sensitized children. | 22554299 |
| Inflammation, Fibrosis Assessment, Connective Tissue Diseases, Peyronie Disease | Altered Intercellular Communication | Peyronie 's disease is an acquired connective tissue disorder of the penile tunica albuginea with fibrosis and inflammation. | 22555030 |
| Inflammation, Demographics Domain, Coronary heart disease, Diabetes Mellitus, Choline Dehydrogenase, Mitochondrial | Altered Intercellular Communication | Angiogenesis plays a role in the pathogenesis of coronary heart disease (CHD) and diabetes mellitus (DM) pathology, and certain angiogenic factors are increased by inflammation. | 22555486 |
| Inflammation, Demographics Domain, Choline Dehydrogenase, Mitochondrial | Altered Intercellular Communication | Sixty-six hemodialysis patients were enrolled in the study, of whom 22 (33.3%) suffered from CHD , 22 (33.3%) from DM, and 28 (42.4%) from inflammation. | 22555486 |
| Inflammation, Demographics Domain, Choline Dehydrogenase, Mitochondrial | Altered Intercellular Communication | These markers were compared between hemodialysis patients with and without CHD, DM, and inflammation. | 22555486 |
| Inflammation, Demographics Domain, Choline Dehydrogenase, Mitochondrial | Altered Intercellular Communication | Neither angiogenin nor VEGFA levels differed significantly between hemodialysis patients with and without CHD, DM, or inflammation. | 22555486 |
| Inflammation, Demographics Domain, Choline Dehydrogenase, Mitochondrial | Altered Intercellular Communication | Plasma angiogenin and VEGFA levels are markedly increased in hemodialysis patients, but not associated with CHD, DM, or inflammation among hemodialysis patients. | 22555486 |
| Inflammation, Snowflake vitreoretinal degeneration, Aphakia, Diabetes Mellitus, Myopia, Pseudophakia, Senility | Altered Intercellular Communication | Several elements can be responsible for vitreous modifications, such as senility, myopia, aphakia, pseudophakia, diabetes, degeneration vitreous retinal hereditary, traumatisms, inflammation. | 22555828 |
| Acoustic Neuroma, Hemorrhage, Inflammation | Altered Intercellular Communication | Biological processes like intratumoral hemorrhage, cell proliferation, microvessel density, and inflammation were analyzed in order to determine their role in vestibular schwannoma development. | 22555941 |
| Inflammation, Neoplasms | Altered Intercellular Communication | Intratumoral hemosiderin, microvessel density, and inflammation were significantly positively correlated with tumor size and the tumor growth index. | 22555941 |
| Inflammation, Endothelial dysfunction, Metabolic Syndrome X | Altered Intercellular Communication | Connection between telomerase activity in PBMC and markers of inflammation and endothelial dysfunction in patients with metabolic syndrome. | 22558213 |
| Inflammation, Metabolic Syndrome X | Altered Intercellular Communication | The present study tried to investigate the implications of telomerase activity with inflammation and impaired endothelial function in patients with metabolic syndrome. | 22558213 |
| Inflammation, Endothelial dysfunction, Diabetes Mellitus | Altered Intercellular Communication | In conclusion, in patients with MS characterised by a strong dyslipidemic profile and low diabetes prevalence, significant telomerase activity was detected in circulating PBMC, along with elevated markers of inflammation and endothelial dysfunction. | 22558213 |
| Metabolic Diseases, Metabolic Syndrome X, MS gene, Cardiovascular Diseases | Altered Intercellular Communication | Metabolic syndrome (MS) is a constellation of metabolic derangements associated with vascular endothelial dysfunction and oxidative stress and is widely regarded as an inflammatory condition, accompanied by an increased risk for cardiovascular disease. | 22558213 |
| Inflammation, Mass Behavior | Altered Intercellular Communication | PEA acts as an endogenous agent with an autacoid local inflammation antagonism and modulates mast cell behavior controlling both acute and chronic inflammation. | 22558609 |
| Inflammation, Ichthyosis Bullosa of Siemens, Irritable Bowel Syndrome | Altered Intercellular Communication | Recent studies suggest that irritable bowel syndrome (IBS) is associated with low-grade inflammation. | 22558797 |
| Inflammation, Bacterial Infections | Altered Intercellular Communication | Autoimmune triggering of inflammation and bacterial infection is hypothesized to be involved in the pathogenesis. | 22560016 |
| Inflammation, Dermatitis, Atopic | Altered Intercellular Communication | Topical corticosteroids are used to treat inflammation and relieve itching in atopic dermatitis, but their use is limited by adverse reactions. | 22560125 |
| Sexual Dysfunction | Altered Intercellular Communication | The relationship between the older antiepileptic drugs (AEDs) and sexual dysfunction has long been known and it is likely to be related to sexual hormonal changes. | 22560189 |
| Inflammatory Bowel Diseases, Inflammation | Altered Intercellular Communication | Patients with inflammatory bowel disease exhibited a very high risk of transfusion-induced red cell alloimmunization, possibly potentiated by inflammation. | 22560809 |
| Inflammation, Atherosclerosis | Altered Intercellular Communication | Inflammation and coagulation markers and kidney function decline: the Multi-Ethnic Study of Atherosclerosis (MESA). | 22560844 |
| Inflammation, Kidney Diseases | Altered Intercellular Communication | The strength and direction of the associations between inflammation and coagulation biomarkers with kidney disease onset and progression remain unclear, especially in a population-based setting. | 22560844 |
| Inflammation, Chronic Kidney Diseases, Cardiovascular Diseases | Altered Intercellular Communication | Inflammation and coagulation biomarkers are associated with decreasing kidney function in ambulatory adults without established cardiovascular disease or chronic kidney disease. | 22560844 |
| Inflammation, Fibrosis Assessment, Retroperitoneal fibrosis | Altered Intercellular Communication | Idiopathic retroperitoneal fibrosis is an uncommon disease characterized by encasement of retroperitoneal structures by fibrosis and chronic inflammation. | 22561019 |
| Cessation of life, Tumor necrosis | Altered Intercellular Communication | Tumour necrosis factor receptor (TNFR)-associated death domain (TRADD) protein is a central adaptor in the TNFR1 signalling complex that mediates both cell death and inflammatory signals. | 22561347 |
| Inflammation, Toxic effect | Altered Intercellular Communication | The most serious acute toxicity was irradiated inflammation of mocosa with Grade 1 to 4 of 16.7%, 60%, 23.3% and 0, respectively. | 22561435 |
| Inflammation, Granuloma | Altered Intercellular Communication | Regarding muscle histopathological findings, in addition to inflammation, 13 patients had chronic myopathic changes and six had granulomatous lesions. | 22561642 |
| Inflammation, Muscular Atrophy, Chronic disease, Myositis | Altered Intercellular Communication | Statistical analysis showed that the clinical features of a chronic disease course, cardiac involvement and muscle atrophy, and the histopathological features of chronic myopathic changes and granulomatous inflammation, were significantly more frequently observed in patients with anti-mitochondrial antibody-positive inflammatory myopathy than in patients who were negative for anti-mitochondrial antibodies. | 22561642 |
| Granulomatous inflammation, Muscular Atrophy, Chronic disease, Myositis | Altered Intercellular Communication | Our study revealed that inflammatory myopathies associated with anti-mitochondrial antibodies were frequently found in patients with the clinical features of a chronic disease course, muscle atrophy and cardiopulmonary involvement, and the characteristic histopathological feature of granulomatous inflammation. | 22561642 |
| Inflammation, Infiltration | Altered Intercellular Communication | sPPP attenuates alveolar inflammation, as demonstrated by the lower neutrophilic/lymphocytic alveolar infiltration, and the secretion of anti-inflammatory rather than proinflammatory mediators. | 22561658 |
| Inflammation, Carcinogenesis, Neoplasms | Altered Intercellular Communication | Intercellular adhesion molecule-1 (ICAM-1), a cell adhesion molecule with a key role in inflammation and immunosurveillance, has been implicated in carcinogenesis by facilitating instability of the tumor environment. | 22562265 |
| Myocarditis | Altered Intercellular Communication | Its relationship with active myocardial inflammation, however, is not well understood. | 22562417 |
| Inflammation, Fibrosis Assessment, Myocardial Infarction, Myocardial, Myocarditis, CTCAE 5.0 | Altered Intercellular Communication | Myocardial edema as a feature of inflammation and myocardial necrosis or fibrosis can be frequently observed in patients with acute myocarditis by cardiovascular magnetic resonance (CMR). | 22562417 |
| Inflammation, Benign prostatic hypertrophy | Altered Intercellular Communication | Progression of benign prostatic hyperplasia (BPH) involves chronic inflammation and immune dysregulation. | 22562653 |
| Hypogonadism, prostatitis | Altered Intercellular Communication | Preclinical studies have demonstrated that prostate inflammation and tissue remodeling are exacerbated by hypogonadism and prevented by testosterone supplementation. | 22562653 |
| Inflammation, Hypogonadism | Altered Intercellular Communication | Even after adjusting for confounding factors, hypogonadism was associated with a fivefold increased risk of intraprostatic inflammation, which was also more severe than that observed in eugonadal BPH patients. | 22562653 |
| Degenerative polyarthritis, Inflammation | Altered Intercellular Communication | In advanced osteoarthritis, when we consider that the inflammatory episodes are expected findings, the early confirmation of the inflammation on US may be particularly valuable in the clinical setting. | 22562715 |
| Intestinal metaplasia, Inflammation | Altered Intercellular Communication | Endoscopic biopsies from the esophagus, gastroesophageal junction and stomach were evaluated for inflammation, the presence of H. pylori and intestinal metaplasia. | 22563195 |
| Inflammation, Sarcopenia, Obesity | Altered Intercellular Communication | It has been suggested that insulin resistance, low-grade inflammation and vitamin D deficiency are associated with obesity and sarcopenia. | 22563924 |
| Inflammation | Altered Intercellular Communication | Insulin resistance, inflammation and vitamin D deficiency were associated with SO in a Korean adult population. | 22563924 |
| Inflammation, Primary malignant neoplasm, Chronic disease | Altered Intercellular Communication | Biomarkers of low-grade systemic inflammation are used to study the associations of inflammation with chronic diseases, including cancer. | 22564866 |
| Inflammation | Altered Intercellular Communication | interleukin-17(+ve) T cells, exhibit increased exofacial redox-regulating enzymes and that peroxiredoxin 2 may be involved in the persistence of pro-inflammatory cells in chronic inflammation. | 22565169 |
| Proctitis, Intestinal Diseases | Altered Intercellular Communication | Surrogate markers of colorectal inflammation are increasingly being recognized as important in differentiating organic from functional intestinal disorders. | 22565607 |
| Inflammation | Altered Intercellular Communication | We evaluated FC as an index of inflammation in consecutive outpatients referred for colonoscopy for chronic, nonbloody diarrhea. | 22565607 |
| Inflammation, Fibrosis Assessment | Altered Intercellular Communication | MRI histology correlation was high for delayed-phase MRI versus fibrosis stage (95% confidence interval [CI] 0.941 < r < 0.976, P = 5 x 10(-7)), but lower for all other comparisons (delayed-phase vs. inflammation and arterial-phase vs. inflammation or fibrosis all showed a CI no greater than 0.64). | 22566123 |
| Inflammation, Chronic Kidney Diseases, Diabetes Mellitus | Altered Intercellular Communication | Inflammation, diabetes, and chronic kidney disease: role of aerobic capacity. | 22566996 |
| Inflammation, Hypersensitivity, Candida (fungus) | Altered Intercellular Communication | Relationship between systemic inflammation and delayed-type hypersensitivity response to Candida antigen in older adults. | 22567155 |
| Inflammation | Altered Intercellular Communication | Research has shown that aging is associated with increased systemic inflammation as well as a reduction in the strength of immune responses. | 22567155 |
| Blood Vessel, Necrosis with inflammation | Altered Intercellular Communication | Churge-Strauss Syndrome belongs to systematic, necrotic inflammation of medium and small vessels diseases. | 22568182 |
| Eosinophilic disorder, Inflammation | Altered Intercellular Communication | Base for recognition was clinical picture and laboratory tests which showed elevetion of inflammation parameters (CRP, ESR), eosinophilia (18%) and p-ANCA antibodies. | 22568182 |
| Airway structure | Altered Intercellular Communication | Alveolar nitric oxide (CA(NO)) is a potential biomarker of small airway inflammation. | 22568828 |
| Necrotizing granulomatous inflammation, Inflammation | Altered Intercellular Communication | Xanthogranulomatous inflammation is a rare form of chronic granulomatous inflammation. | 22568924 |
| Oophoritis, Inflammation, Uterine Fibroids, Endometriosis of pelvis, Bacterial Infections, Xanthogranulomatous salpingitis | Altered Intercellular Communication | Chronic inflammation due to inadequate treatment of bacterial infection, coupled with pelvic endometriosis and uterine leiomyoma may have led to xanthogranulomatous salpingitis and oophoritis. | 22568924 |
| Inflammation, S100A4 protein, human | Altered Intercellular Communication | Complete removal is necessary to prevent fulminant inflammation and disorders of function; furthermore the risk of a malignant transformation is seldom but present. | 22570008 |
| Inflammation, No metabolic abnormalities, Impaired cognition | Altered Intercellular Communication | There is increasing evidence from basic science and human epidemiological studies that inflammation, oxidative stress, and metabolic abnormalities are associated with age-related cognitive decline and impairment. | 22570133 |
| Inflammation | Altered Intercellular Communication | Our findings also suggest that autophagy preserves arterial endothelial function by reducing oxidative stress and inflammation and increasing NO bioavailability. | 22570377 |
| Inflammation, Plaque, Atherosclerotic | Altered Intercellular Communication | The importance of chronic inflammation in atherogenesis and cytokine involvement in all stages of atherosclerotic plaque development is now obvious. | 22570926 |
| Lacrimal gland cyst, Inflammation, Traumatic injury | Altered Intercellular Communication | Lacrimal duct cyst is a rare clinical entity and has been postulated to result from localized inflammation or trauma to conjunctiva. | 22571599 |
| Tracheobronchitis, Pneumonitis, Edema, Pneumonia | Altered Intercellular Communication | Common findings included pulmonary interstitial inflammation and edema, tracheobronchitis, and pneumonia. | 22571830 |
| Inflammation, Ulcerative Colitis | Altered Intercellular Communication | As a result of mucosal inflammation in ulcerative colitis, oxidative stress can occur. | 22572519 |
| Inflammation | Altered Intercellular Communication | Polymorphisms in 15 genes involved in inflammation or responses to oxidative stress were characterized in the subjects. | 22572643 |
| Carcinoma of lung, Pneumonitis | Altered Intercellular Communication | The expression level of GRIM-19 was significantly different between lung cancer and lung inflammation. | 22573109 |
| Carcinoma of lung, Pneumonitis | Altered Intercellular Communication | Furthermore, we found GRIM-19 to be primarily located in the cytoplasm in lung inflammation tissues, but located in the nucleus in lung cancer tissues. | 22573109 |
| Inflammation, Pain Distress Question | Altered Intercellular Communication | We describe two cases of peristomal inflammation which resulted in pain, poor adhesion of the stoma bag and faecal leaking. | 22573469 |
| Inflammation, Carcinoma of lung | Altered Intercellular Communication | Multistage analysis of variants in the inflammation pathway and lung cancer risk in smokers. | 22573796 |
| Inflammation, Carcinoma of lung | Altered Intercellular Communication | Variants in multiple genes in inflammation pathways may contribute to risk of lung cancer. | 22573796 |
| Inflammation, Carcinoma of lung | Altered Intercellular Communication | We therefore conducted a three-stage comprehensive pathway analysis (discovery, replication, and meta-analysis) of inflammation gene variants in ever-smoking lung cancer cases and controls. | 22573796 |
| Inflammation, Dental Plaque | Altered Intercellular Communication | Telomere and telomerase may play key roles in the etiological factors such as inflammation and AS plaque. | 22574607 |
| Inflammation | Altered Intercellular Communication | Obesity-related early systemic inflammation might be involved in suboptimal bone accrual, particularly in overweight girls. | 22574856 |
| Inflammation, Chronic disease | Altered Intercellular Communication | The discovery of a form of low-grade systemic and chronic inflammation ("metaflammation"), linked to inducers (broadly termed "anthropogens") associated with modern man-made environments and lifestyles, suggests an underlying basis for chronic disease that could provide a 21st-century equivalent of the germ theory. | 22575080 |
| Inflammation | Altered Intercellular Communication | The Medtronic RHS may induce less systemic inflammation than conventional CPB systems, particularly when cardiotomy suction was used, but it did not result in improved clinical benefit. | 22576032 |
| Colorectal Carcinoma | Altered Intercellular Communication | Inflammation-based prognostic system predicts postoperative survival of colorectal cancer patients with a normal preoperative serum level of carcinoembryonic antigen. | 22576063 |
| Primary malignant neoplasm | Altered Intercellular Communication | On the other hand, inflammation-based prognosis, assessed by the Glasgow Prognostic Score (GPS), has been established as one of the important prognostic factors of survival after surgery for several types of cancer. | 22576063 |
| Inflammation, Breast Carcinoma, Obesity | Altered Intercellular Communication | These findings help to explain the link among obesity, low-grade chronic inflammation, and breast cancer with important clinical implications. | 22576212 |
| Inflammatory Bowel Diseases, Inflammation, Rheumatoid Arthritis, Spondylitis | Altered Intercellular Communication | Mean platelet volume (MPV) is inversely correlated with inflammation in inflammatory bowel diseases, rheumatoid arthritis, and ankylosing spondylitis as shown in the previous studies. | 22576316 |
| ARCN1 gene, Inflammation | Altered Intercellular Communication | The results suggest that assessment of MPV in COPD exacerbation may indicate systemic inflammation. | 22576316 |
| Inflammation, Lymphoma | Altered Intercellular Communication | [Malignant lymphoma presenting as inflammation of unknown origin]. | 22576571 |
| Inflammation, Rheumatism | Altered Intercellular Communication | We classified underlying diseases presenting as inflammation of unknown origin in division of rheumatic diseases. | 22576571 |
| Inflammation, Rheumatism | Altered Intercellular Communication | ML ranked first among causes of inflammation of unknown origin at the division of Rheumatic Diseases, and FDG-PET/CT proved to be useful for biopsy site selection. | 22576571 |
| Nausea, Bothered by Vomiting, Headache, physiopathological | Altered Intercellular Communication | Its clinical symptoms are characterized by sudden onset of headache, nausea, vomiting, ophthalmic symptoms and hormonal dysfunction. | 22576705 |
| Myocarditis | Altered Intercellular Communication | Pericardial VEGF levels correlated positively with markers of pericardial inflammation, whereas pericardial bFGF levels showed a negative correlation. | 22577248 |
| Inflammation, Vasculitis, CTCAE, Endothelial dysfunction, Cardiovascular system | Altered Intercellular Communication | This is a rare generalized systemic vasculitis typical of the early childhood characterized by inflammation and endothelial dysfunction with a high risk for cardiovascular fatal events. | 22578402 |
| Inflammation, Lymphoma | Altered Intercellular Communication | [Lymphoma suspected cervical lymph node inflammation indicating secondary syphilis]. | 22579090 |
| Inflammation | Altered Intercellular Communication | Initial fine needle aspirations and the following extirpation of a cervical lymph node revealed severe chronic inflammation. | 22579090 |
| Inflammation, Venous Thromboembolism, vinyltriethoxysilane | Altered Intercellular Communication | The pathogenesis of venous thromboembolism (VTE) is linked to inflammation and oxidant production, although specific markers for these pathways with pathological relevance to VTE have not been explored. | 22580301 |
| Inflammation, vinyltriethoxysilane | Altered Intercellular Communication | Therefore, nitrated fibrinogen may serve as a marker of inflammation and oxidative stress in VTE. | 22580301 |
| Inflammation, vinyltriethoxysilane | Altered Intercellular Communication | These data indicate that nitrated fibrinogen is an oxidative risk marker in VTE, providing a novel mechanistic link between oxidant production, inflammation, and VTE. | 22580301 |
| Vascular System Injuries, Inflammation, Atherosclerosis | Altered Intercellular Communication | Osteopontin (OPN) is a multifunctional protein associated with vascular injury and has been linked to atherosclerosis and inflammation. | 22580396 |
| Inflammation, Knee pain | Altered Intercellular Communication | Systemic inflammation is an independent predictor of worsening knee pain over 5 years. | 22580582 |
| Inflammation, Fibrosis Assessment, Malignant Neoplasms | Altered Intercellular Communication | Inhaled asbestos fibres are known to cause inflammation processes with the result of lung or pleural fibrosis and malignancies. | 22580886 |
| SLC5A8 wt Allele, Thyroiditis | Altered Intercellular Communication | The results indicate that TPOAb titer is associated with the degree of thyroid inflammation and that detection of TPOAb is a very specific means of diagnosing AIT. | 22581205 |
| Sepsis, Communicable Diseases, Inflammation | Altered Intercellular Communication | A classification model comprising these markers resulted in 80% and 70% correct classifications in a training set and a test set, respectively.This study demonstrates that acylcarnitines and glycerophosphatidylcholines may be helpful for differentiation of infectious from noninfectious systemic inflammation due to their significantly higher concentration in sepsis patients. | 22581935 |
| ARCN1 gene, Inflammation | Altered Intercellular Communication | At 1 year it decreased, never reaching normal values in the majority of our patients thus confirming the presence of a persistent inflammation in COPD. | 22582486 |
| Infarction, Inflammation, Blood Clot, Rupture | Altered Intercellular Communication | All tissue material was resectioned and stained with the immunohistochemical reagent, cytokeratin (AE1/AE3/PKC26), and that made it possible to divide the material into two different disease categories: (1) 36 biopsies from 30 cases had tissue inflammation after rupture of keratin-rich epidermal cysts, which we call 'horny cell inflammation', followed by extensive cutaneous thrombi and infarcts, and (2) 21 biopsies from 20 cases had 'apocrinitis' defined here as an inflammatory destruction of apocrine skin glands, and partly of close eccrine glands. | 22583355 |
| Inflammation | Altered Intercellular Communication | There were significant transient cardiac surgery-related fluctuations in 1,25-dihydroxyvitamin D and the aforementioned parameters of mineral metabolism, inflammation, and immune status. | 22584760 |
| Pain Distress Question, Inflammation, Primary gout, Exacerbation of cGVHD | Altered Intercellular Communication | Canakinumab provided significant pain and inflammation relief and reduced the risk of new flares in these patients with acute gouty arthritis. | 22586173 |
| Acute and chronic inflammation | Altered Intercellular Communication | A prospective comparative study with a pre-post design has been performed consecutively enrolling 33 (males 70 %) patients of both genders older than 12 years of age, affected by chronic sinonasal inflammation. | 22588193 |
| Inflammation, Necrosis | Altered Intercellular Communication | Typically, a pattern of acute inflammation occurs, with a predominantly lymphoid cellular infiltrate followed by necrosis. | 22588424 |
| Benign prostatic hypertrophy, prostatitis | Altered Intercellular Communication | The effect of prostate tissue inflammation in benign prostatic hyperplasia on enhancer of zeste homolog 2 ribonucleic acid expression. | 22588437 |
| prostatitis | Altered Intercellular Communication | This supports the possible involvement of EZH2 mRNA overexpression in the development of prostate inflammation, and its new regulatory role in suppressing the expression of some inflammatory network genes. | 22588437 |
| Inflammation, Heart failure, Muscle Cells | Altered Intercellular Communication | We hypothesized that outdoor temperature in the Boston, Massachusetts, area (1- to 4-day moving averages) would be associated with higher levels of biomarkers of inflammation and myocyte injury in a repeated-measures study of individuals with stable heart failure. | 22588803 |
| Macular edema due to diabetes mellitus, dimethyl ether | Altered Intercellular Communication | Inflammation contributes significantly to the pathogenesis of diabetic macular edema (DME). | 22589436 |
| MIRLET7E gene | Altered Intercellular Communication | Among these, four microRNAs (hsa-miR-1, hsa-let-7e, hsa-miR-9, and hsa-miR-182) were known to be associated with the inflammatory signaling pathway. | 22589448 |
| Airway structure, Parenchyma, ARCN1 gene | Altered Intercellular Communication | These data suggest that cigarette smoke augments the expression and responses of TLR3 in human macrophages, and this may contribute to neutrophilic airway inflammation and parenchymal destruction in the lungs of smokers and patients with COPD. | 22591330 |
| Inflammation, Ischemic stroke | Altered Intercellular Communication | This stroke-specific gene expression profiling provides valuable information about the role of peripheral inflammation to the pathophysiological mechanism of ischemic stroke. | 22591946 |
| Inflammation | Altered Intercellular Communication | It is suggested that analysis of PISF may serve for detection of inflammation. | 22592038 |
| Inflammation | Altered Intercellular Communication | Our adolescent data suggest that greater consumption of dietary fiber is associated with lower visceral adiposity and multiple biomarkers implicated in inflammation. | 22593589 |
| Inflammation | Altered Intercellular Communication | Short-chain fatty acids (SCFAs) are important metabolic products of subgingival organisms and their concentrations are associated with the status of inflammation. | 22594616 |
| Trachoma | Altered Intercellular Communication | This integrated mapping was followed by a 20-cluster trachoma survey in each district that surpassed the WHO-defined threshold of 10% prevalence of trachomatous inflammation-follicular (TF). | 22594642 |
| Ischemia, Primary malignant neoplasm, Inflammation | Altered Intercellular Communication | These include ischemia and inflammation, pre-cancer and cancer. | 22594983 |
| Degenerative polyarthritis, Inflammation, Cartilage damage | Altered Intercellular Communication | Serum adipokines in osteoarthritis; comparison with controls and relationship with local parameters of synovial inflammation and cartilage damage. | 22595228 |
| Degenerative polyarthritis, Inflammation, Cartilage damage | Altered Intercellular Communication | The aim of this study is to compare serum adipokine levels between end-stage knee OA patients and controls and to relate these serum levels to local parameters of cartilage damage and synovial inflammation. | 22595228 |
| Inflammation, Degenerative disorder of cartilage | Altered Intercellular Communication | Cartilage and synovial tissue were collected at TKR surgery and assessed for cartilage degeneration and synovial inflammation by histochemistry and biochemical analyses. | 22595228 |
| Inflammation, Cartilage damage | Altered Intercellular Communication | No associations between serum levels of adipokines and cartilage damage (histochemistry, proteoglycan content) were found whereas weak but positive associations with synovial inflammation were found [adiponectin and interleukin-1b (IL-1b), stand beta = 0.172, P = 0.02; resistin and histology, stand beta = 0.183, P = 0.034, adjusted for demographics]. | 22595228 |
| Degenerative polyarthritis, Inflammation, Cartilage damage | Altered Intercellular Communication | Associations of systemic adipokines with local synovial tissue inflammation were found, although not represented by similar relations with cartilage damage, suggesting that adipokines are of relevance in the inflammatory component of OA. | 22595228 |
| Inflammation, Ulceration, CTCAE, S100A4 protein, human, Gastric Adenoma | Altered Intercellular Communication | Gastric adenomyoma is usually asymptomatic but could cause obstruction, inflammation, ulceration, and malignant transformation. | 22595594 |
| Parkinson Disease, Tremor, CTCAE 3.0 | Altered Intercellular Communication | We hypothesize that the serotonin neurotransmission system may also play a role as it does in tremor in Parkinson disease. | 22595620 |
| Inflammation, "Alzheimers Disease | Altered Intercellular Communication | Male sex hormones and systemic inflammation in Alzheimer disease. | 22596080 |
| Inflammation, "Alzheimers Disease | Altered Intercellular Communication | Male sex hormones and systemic inflammation in Alzheimer disease. | 22596080 |
| Autoimmune Diseases, Inflammation, Lymphoma | Altered Intercellular Communication | Marginal zone lymphomas are indolent B-cell lymphomas associated with autoimmunity and chronic inflammation. | 22596180 |
| Inflammation, Discitis, Bone structure of thoracic vertebra, Edema | Altered Intercellular Communication | Urgent MRI showed discitis at the disc between cervical vertebra seven (C7), thoracic vertebra one (T1) and lumbar vertebra three and four (L3-4), associated dural inflammation, stenosis of the cervical spinal canal and cervical cord oedema at the level of C3. | 22605834 |
| Ulcer, Granulomatous inflammation, Stenosis, Granuloma | Altered Intercellular Communication | Biopsy of the stricture revealed ulcer with granulomatous inflammation including well-formed granulomas and an infiltrate of histiocytes within the lamina propria. | 22605846 |
| Inflammation | Altered Intercellular Communication | Gene ontology analysis indicated that the over-expressed genes in CD90(+)CSCs were associated with inflammation, drug resistance and lipid metabolism. | 22606345 |
| Structure of temporalis muscle, Traumatic injury, Aplasia/Hypoplasia of the mandible | Altered Intercellular Communication | There are multiple theories as to the causes of coronoid process hyperplasia of the mandible, including trauma, temporalis muscle hyperactivity, hormonal stimulus, and genetic inheritance. | 22606859 |
| Inflammation, Anemia | Altered Intercellular Communication | Relationship between markers of inflammation and anaemia in children of Papua New Guinea. | 22607654 |
| Inflammation, Anemia | Altered Intercellular Communication | There are no expert group recommendations on whether to or how to account for markers of inflammation in presenting results on anaemia prevalence. | 22607654 |
| ARCN1 gene, Coughing, Airway structure | Altered Intercellular Communication | COPD is characterized by increased cough, mucus production, and airway inflammation. | 22608352 |
| Inflammation, Electrocardiogram: myocardial infarction (finding), Coronary Arteriosclerosis | Altered Intercellular Communication | With the growing understanding of the role of inflammation in patients with atherosclerotic disease, studies have focused on high-sensitivity C-reactive protein (hs-CRP) and other inflammatory markers in their association with outcomes in ST-segment elevation myocardial infarction. | 22608360 |
| Inflammation, Certified Midwife | Altered Intercellular Communication | Cryptococci and inflammation in the central nervous system may play important roles in the pathogenesis of CM. | 22608531 |
| Inflammation | Altered Intercellular Communication | Low intensity of inflammation and effective surgical CSF drains for increased intracranial pressure and cryptococci removal may contribute to lower mortality in HIV-infected patients. | 22608531 |
| Inflammation, Infection | Altered Intercellular Communication | One year of pomegranate juice intake decreases oxidative stress, inflammation, and incidence of infections in hemodialysis patients: a randomized placebo-controlled trial. | 22609423 |
| Inflammation, Atherosclerosis | Altered Intercellular Communication | Increased systemic inflammation and oxidative stress are well established as nontraditional key players in the pathogenesis of atherosclerosis and are also involved in the innate immunity dysregulation in hemodialysis (HD) patients. | 22609423 |
| Inflammation, Lupus Erythematosus, Systemic, Autoimmune Diseases, Refractory anemias, Tumor necrosis, Rheumatoid Arthritis, Lupus Erythematosus | Altered Intercellular Communication | Many cytokines are involved in the pathogenesis of autoimmune diseases and are recognized as relevant therapeutic targets to attenuate inflammation, such as tumor necrosis factor (TNF)-a in rheumatoid arthritis (RA) and interferon (IFN)-a/g in systemic lupus erythematosus (SLE). | 22610275 |
| Inflammation, Pulmonary Emphysema | Altered Intercellular Communication | Excessive apoptosis and prolonged inflammation of alveolar cells are associated with the pathogenesis of pulmonary emphysema. | 22610351 |
| Inflammation, Postoperative Complications, Corneal edema | Altered Intercellular Communication | Postoperative complications included corneal edema (2 eyes), Descemet folds (1 eye), intraocular pressure elevations (3 eyes), and pronounced anterior segment inflammation (1 eye). | 22610720 |
| Liver carcinoma, Communicable Diseases, Hepatitis C, Acute and chronic inflammation, FAM126A gene | Altered Intercellular Communication | Hepatitis C virus (HCV) infection usually induces chronic hepatic inflammation, which favors the initiation and progression of hepatocellular carcinoma (HCC). | 22610915 |
| Inflammation | Altered Intercellular Communication | Moreover, microRNA-155 (miR-155) plays an important role in regulating both inflammation and tumorigenesis. | 22610915 |
| Inflammation, Primary malignant neoplasm | Altered Intercellular Communication | However, little is known about whether and how miR-155 provides the link between inflammation and cancer. | 22610915 |
| Inflammation | Altered Intercellular Communication | This could be attributed to the oxidative stress, inflammation neuronal apoptosis and an alteration in the activities of the signaling enzymes. | 22610977 |
| Inflammation, Thrombosis, Communicable Diseases, Damage, Thrombocytopenia | Altered Intercellular Communication | Recent studies suggest that DNA and histones are released during inflammation or infection and stimulate coagulation, thrombosis, thrombocytopenia, and organ damage in mice. | 22611154 |
| Inflammation, Fibrosis Assessment | Altered Intercellular Communication | Histological inflammation grading and fibrosis staging were evaluated by H and E staining and Van Gieson's method. | 22611323 |
| Inflammation, Chronic small plaque psoriasis, Psoriasis | Altered Intercellular Communication | To explore the possible role of osteopontin (OPN) in chronic plaque psoriasis and understand the role of inflammation in psoriasis. | 22611763 |
| Disability or Permanent Damage, Traumatic | Altered Intercellular Communication | The extent of irreversible neuroaxonal damage is the key determinant of permanent disability in traumatic and inflammatory conditions of the central nervous system (CNS). | 22612622 |
| Inflammation, Pustulosis of Palms and Soles | Altered Intercellular Communication | Alitretinoin abrogates innate inflammation in palmoplantar pustular psoriasis. | 22612660 |
| Atherosclerosis | Altered Intercellular Communication | These data indicates that ABCA1, ABCG1, and SR-BI are reduced in various populations under subclinically inflammatory conditions, which may potentially lead to impairing reverse cholesterol transport and developing atherosclerosis. | 22614118 |
| Inflammation, Primary malignant neoplasm, Hypoproteinemia | Altered Intercellular Communication | Circulating myeloid-derived suppressor cells are increased and correlate to immune suppression, inflammation and hypoproteinemia in patients with cancer. | 22614133 |
| malignant disease, Inflammation | Altered Intercellular Communication | It has been reported that MDSCs are generated by malignant diseases or inflammation. | 22614133 |
| Inflammation, Hypoproteinemia | Altered Intercellular Communication | These data also suggest that they are related to chronic inflammation and that their levels are increased further in the terminal stages of patients whose nutritional status is impaired as observed in hypoproteinemia. | 22614133 |
| Inflammation | Altered Intercellular Communication | Furthermore, the inflammation score was significantly higher in H. pylori-infected del/del homozygotes compared to ins carriers. | 22614238 |
| Airway structure, Inflammation, Respiration Disorders | Altered Intercellular Communication | Although airway inflammation begins early in life in children with chronic respiratory diseases, current methods to assess this inflammation are invasive and entail significant risk. | 22615171 |
| Airway structure | Altered Intercellular Communication | The EBC AMP/Ado ratio correlates with measures of infant lung function and may be a less invasive means of monitoring airway inflammation in this population. | 22615171 |
| Inflammation, Primary malignant neoplasm | Altered Intercellular Communication | This pilot clinical trial identified the oral microflora of the peri-implant sulcus of cancer patients with jaw reconstruction and compared sites with and without clinical signs of inflammation. | 22616064 |
| Communicable Diseases, Colonization, allergic inflammation | Altered Intercellular Communication | It remains unanswered whether persistent allergic inflammation in nasal mucosa alters bacterial colonization and infection. | 22616074 |
| Pancreatic carcinoma | Altered Intercellular Communication | Inflammation marker and risk of pancreatic cancer: a nested case-control study within the EPIC cohort. | 22617158 |
| Inflammation | Altered Intercellular Communication | We hypothesized that increased RDW would be associated with isolated CAE because both are associated with inflammation. | 22619398 |
| Inflammation, Sclerosing peritonitis | Altered Intercellular Communication | Sclerosing peritonitis: a rare but fatal complication of peritoneal inflammation. | 22619486 |
| Inflammation, Sclerosing peritonitis | Altered Intercellular Communication | Sclerosing peritonitis is a rare form of peritoneal inflammation with an often fatal outcome. | 22619486 |
| Tuberculoma, Inflammation, Tuberculosis | Altered Intercellular Communication | The histopathological report was caseating granulomatous inflammation involving cerebellar parenchyma; suggestive of tuberculoma, PCR for M. Tuberculosis complex, using brain tissue from formalin-fixed paraffin-embeded block, yields positive result for M. Tuberculosis complex. | 22619899 |
| Lichen - organism, Inflammation, Localized scleroderma, Systemic Scleroderma | Altered Intercellular Communication | Histopathologically, perineural inflammation was observed in 49% of cases, and may serve, in addition to other features including lichen sclerosis-like changes (observed in exclusively nine cases of morphea), more diffuse dermal and less subcutaneous sclerosis, and intense inflammation, as clues favouring diagnosis of morphea over systemic sclerosis. | 22620486 |
| Lichen - organism, Inflammation, Localized scleroderma, Systemic Scleroderma | Altered Intercellular Communication | Histopathologically, perineural inflammation was commonly observed and may serve in addition to lichen sclerosis-like changes and intense inflammation as clues favouring diagnosis of morphea over systemic sclerosis. | 22620486 |
| Inflammatory abnormality of the eye, Dryness of eye | Altered Intercellular Communication | Patients with severe dry eye or any other condition that induces ocular inflammation were excluded. | 22620852 |
| Bacteremia, Meningitis | Altered Intercellular Communication | Mutant bacteria also induced markedly reduced meningeal inflammation and brain pathology compared with wild type, despite similar levels of bacteremia. | 22622042 |
| Inflammation | Altered Intercellular Communication | L-carnitine plays a critical role in fatty acid transport into the mitochondria and may thus influence inflammation and myocardial function. | 22622056 |
| Inflammation, Fibrosis Assessment, Atrial Fibrillation, Atrial Fibrillation by ECG Finding | Altered Intercellular Communication | Fibrosis and inflammation may play a significant role in the pathogenesis of atrial fibrillation (AF) recurrence. | 22622138 |
| Inflammation, Hyperglycemia | Altered Intercellular Communication | Low-grade inflammation in young adults exposed to intrauterine hyperglycemia. | 22622155 |
| Hyperglycemia, Inflammation, Overweight | Altered Intercellular Communication | Maternal overweight but not exposure to intrauterine hyperglycemia was associated with low-grade inflammation in adult offspring. | 22622155 |
| Inflammation, Neoplasms | Altered Intercellular Communication | Transient systemic inflammation accompanying surgery could be part of the metastatic tumor seeding process and could have been effectively blocked by perioperative anti-inflammatory agents. | 22622810 |
| Inflammation, Metabolic Syndrome X, MS gene | Altered Intercellular Communication | The metabolic syndrome (MS) is characterized by chronic inflammation. | 22623143 |
| Airway structure, Asthma | Altered Intercellular Communication | A high fraction of nitric oxide in exhaled breath (FeNO) has been suggested to be a marker of ongoing airway inflammation and poorly controlled disease in asthma. | 22624949 |
| Inflammation | Altered Intercellular Communication | Chronic inflammation as predictor of 1-year hospitalization and mortality in elderly population. | 22624958 |
| Inflammation | Altered Intercellular Communication | Systemic low-grade inflammation is thought to be associated with an increased risk of adverse clinical outcomes in elderly population. | 22624958 |
| Inflammation | Altered Intercellular Communication | Protein expression differences were found in debris from patients with high systemic inflammation compared with debris from patients with low systemic inflammation. | 22626270 |
| Crypt abscess, Ulcerative Colitis, Edema, Ulcer, Crypt, Erythema, Inflammatory disease of mucous membrane | Altered Intercellular Communication | Their ileocolonoscopy showed diffuse mucosal erythema, oedema, friability and multiple irregular ulcers, and histopathological examination of colonic specimen revealed diffuse chronic mucosal inflammation, crypt distortion and crypt abscesses suggesting ulcerative colitis. | 22626504 |
| Inflammatory Bowel Diseases, Inflammation, Ulcerative Colitis, Crohn Disease | Altered Intercellular Communication | Inflammatory bowel disease, a chronic inflammation of the intestinal tract, presents in two variations, Ulcerative Colitis (UC) and Crohn's disease (CD). | 22626506 |
| Bronchial Hyperreactivity, Airway structure, AHR wt Allele, MS4A2 wt Allele, Asthma | Altered Intercellular Communication | We investigated the association between genetic variation in this region with asthma, lung function, airway inflammation, hyperresponsiveness (AHR), and atopy in a case-control study of United Kingdom adults. | 22626592 |
| Inflammation, Postoperative Period, Endothelial dysfunction, Obesity | Altered Intercellular Communication | Obesity increases oxidative stress, endothelial dysfunction, and inflammation, but the effect of obesity on postoperative AKI is not known. | 22626819 |
| Inflammation, Chronic Kidney Diseases, Cardiovascular Diseases | Altered Intercellular Communication | Inflammation is closely associated with cardiovascular disease, the leading cause of mortality in patients with CKD. | 22626963 |
| Inflammation, Osteolysis, Necrosis, Failure (biologic function) | Altered Intercellular Communication | Therefore, peri-implant osteolysis in early TAR implant failure seems to be caused by the RANKL-driven chronic foreign body inflammation directed against, not implant-derived particles, but against necrotic autologous tissues. | 22627031 |
| Inflammation, Interstitial inflammation | Altered Intercellular Communication | Histopathologic examination (n = 14) showed predominantly neutrophilic perivascular and interstitial inflammation (57%) or predominantly mononuclear cell perivascular inflammation (29%), with eosinophils in 50% of cases. | 22627038 |
| Inflammation, Duodenitis, Esophagitis | Altered Intercellular Communication | Gastrointestinal endoscopy and biopsies revealed esophagitis with some eosinophils and duodenitis with eosinophilic inflammation. | 22627372 |
| Inflammatory Bowel Diseases, Inflammation, Colorectal Carcinoma | Altered Intercellular Communication | Type of IBD, gender, concomitant PSC, pseudopolyps, extent of inflammation, and medication use were not related to early CRC (p > 0.05). | 22627504 |
| Inflammation | Altered Intercellular Communication | Magnetic resonance imaging revealed inflammation around the sacroiliac joint with abscess formation. | 22627656 |
| Granulomatosis, Inflammation, Systemic Vasculitis | Altered Intercellular Communication | Granulomatosis with polyangiitis involves sustained mucosal inflammation that is rich in B-cell survival factors and autoantigen. | 22627727 |
| Airway structure | Altered Intercellular Communication | Elevated fractional excretion of exhaled nitric oxide (FENO) reflects airway inflammation, but few studies have established its normal values. | 22628492 |
| Refractory anemias, Arthritis, Cartilage damage, Damage | Altered Intercellular Communication | These results suggest a role of DC2C/CPII as a marker of ongoing structural joint damage with the least association with CRP, and that irreversible cartilage damage in established RA limits restoration of the C2C/CPII level, even with tight control of joint inflammation. | 22629396 |
| Icterus, Inflammation, Fibrosis Assessment, Biliary calculi | Altered Intercellular Communication | According to Courvoisier's law; if gallbladder is palpable in a jaundiced patient, it is unlikely to be due to gallstones, because stones would have given rise to chronic inflammation and subsequently fibrosis of gallbladder therefore, rendering it incapable of dilatation. | 22630101 |
| Retinal Detachment, Choroidal Detachment, Inflammation, Uveal Effusion Syndrome | Altered Intercellular Communication | Uveal effusion syndrome is characterized by annular ciliochoroidal detachment, shifting non-rhegmatogenous retinal detachment, unremarkable inflammation in the anterior eye segment and normal intraocular pressure. | 22630106 |
| Barrett Esophagus, Inflammation | Altered Intercellular Communication | The role of inflammation both in the development and in the advance of Barrett's esophagus (BE) has not been elucidated. | 22630608 |
| Inflammation, Esophagitis | Altered Intercellular Communication | Previous diagnosis of esophagitis correlated to the degree of inflammation. | 22630608 |
| Pain Distress Question, Blurred vision, Inflammation | Altered Intercellular Communication | In all, 90.7% of the patients presented with blurred vision, and 25.6% with pain or inflammation. | 22633214 |
| Inflammation, Total abdominal hysterectomy, Hemolysis (biological function) | Altered Intercellular Communication | The association of hemolysis, ineffective erythropoiesis, and inflammation with the TAH warrants further study. | 22633300 |
| Inflammation | Altered Intercellular Communication | These findings indicate an important interaction between sex and inflammation in the healing response of vein grafts for LEB. | 22633420 |
| vascular inflammations, Cardiovascular Diseases | Altered Intercellular Communication | Insulin and leptin are important markers of insulin resistance and vascular inflammation in metabolic and cardiovascular diseases. | 22633795 |
| Inflammation, Malnutrition | Altered Intercellular Communication | Malnutrition is common in dialysis patients and is attributed to decreased food intake, and/or chronic systemic inflammation linked to dialysis-related comorbidities and complications. | 22633989 |
| Intraocular inflammation, Pain Distress Question, Hyperemia | Altered Intercellular Communication | Decreased visual acuity, intraocular inflammation, pain and conjunctival hyperemia were found in all patients. | 22634027 |
| Inflammation, Neoplasms | Altered Intercellular Communication | Immunohistochemical assessment of markers of inflammation, cell cycle, and apoptosis was carried out on tumor biopsies. | 22634319 |
| Inflammation, Metabolic Syndrome X, Atherosclerosis | Altered Intercellular Communication | Prediction of vascular events in subjects with subclinical atherosclerosis and the metabolic syndrome: the role of markers of inflammation. | 22634975 |
| Inflammation, Atherosclerosis | Altered Intercellular Communication | These findings confirm a worst vascular outcome in subjects with more criteria for the diagnosis of the MS and further suggest the need of future research to understand the combined role of inflammation and the MS in the progression from subclinical to clinical atherosclerosis. | 22634975 |
| Inflammation, Observation Method - Coagulation, Aortic Aneurysm, Abdominal | Altered Intercellular Communication | Patterns of markers of inflammation, coagulation and vasoconstriction during follow-up of abdominal aortic aneurysms. | 22634983 |
| Inflammation, Observation Method - Coagulation, Aortic Aneurysm, Abdominal, Endothelial dysfunction, APP gene | Altered Intercellular Communication | The etiology of abdominal aortic aneurysm (AAA) includes inflammation, coagulation, and endothelial dysfunction. | 22634983 |
| Inflammation, Antiphospholipid Syndrome | Altered Intercellular Communication | 8-isoprostane, prostaglandin E2, C-reactive protein and serum amyloid A as markers of inflammation and oxidative stress in antiphospholipid syndrome: a pilot study. | 22638905 |
| Inflammation, Antiphospholipid Syndrome | Altered Intercellular Communication | To test the inflammation and oxidative stress hypothesis in antiphospholipid syndrome (APS) patients and to identify possible associations with clinical and laboratory features of the disease. | 22638905 |
| Inflammation, Cardiovascular Diseases | Altered Intercellular Communication | C-reactive protein (CRP) is a central component of innate immune defenses, and high sensitivity CRP has emerged as an important biomarker of chronic inflammation and cardiovascular disease risk. | 22639072 |
| Inflammation | Altered Intercellular Communication | The application of current guidelines for the assessment of chronic inflammation failed to detect a single case of "high risk" CRP. | 22639072 |
| Inflammation | Altered Intercellular Communication | It documents a pattern of variation over time that is distinct from prior research, with no evidence for chronic low-grade inflammation. | 22639072 |
| Inflammation | Altered Intercellular Communication | These results may have substantial implications for research on inflammation and diseases of aging globally, as well as for scientific understandings of the regulation of inflammation. | 22639072 |
| Hashimoto Disease, Inflammation, Haiti | Altered Intercellular Communication | The relationship between inflammation, Hashimoto's thyroiditis (HT) and insulin resistance is still controversial. | 22639339 |
| Inflammation, Metabolic Syndrome X, Bipolar Disorder | Altered Intercellular Communication | Depressive symptoms in older people with metabolic syndrome: is there a relationship with inflammation? | 22639424 |
| Inflammation, ETV3 wt Allele, Bipolar Disorder | Altered Intercellular Communication | MetS and inflammation are independently associated with depressive symptoms in older people. | 22639424 |
| Inflammation | Altered Intercellular Communication | Low-grade chronic inflammation and superoxide anion production by NADPH oxidase are the main determinants of physical frailty in older adults. | 22640231 |
| Inflammation | Altered Intercellular Communication | Low-grade chronic inflammation and oxidative stress, mediated partly by the superoxide anion produced by NADPH oxidase, are closely linked and could be involved in age-related physical decline. | 22640231 |
| Inflammation | Altered Intercellular Communication | Superoxide production and inflammation markers, such as fibrinogen, were more important in slow walkers (p = 0.004 and p = 0.006, respectively). | 22640231 |
| Inflammation | Altered Intercellular Communication | Physical frailty in older people is associated with superoxide anion overproduction by NADPH oxidase and low-grade chronic inflammation. | 22640231 |
| Inflammation | Altered Intercellular Communication | Omega-3 supplementation lowers inflammation in healthy middle-aged and older adults: a randomized controlled trial. | 22640930 |
| Inflammation, Depression, CTCAE | Altered Intercellular Communication | Observational studies have linked lower levels of omega-3 (n-3) polyunsaturated fatty acids (PUFAs) with inflammation and depression. | 22640930 |
| Inflammation, Overweight | Altered Intercellular Communication | Our data suggest that n-3 PUFAs can reduce inflammation in overweight, sedentary middle-aged and older adults, and thus could have broad health benefits. | 22640930 |
| Ischemia, Inflammation, Urinary bladder sphincter dysfunction | Altered Intercellular Communication | Involvement of TL1A and DR3 in induction of ischaemia and inflammation in urinary bladder dysfunction in the elderly. | 22641456 |
| Detrusor instability, Inflammation, Bladder dysfunction, Ischemia | Altered Intercellular Communication | Bladder dysfunction due to detrusor instability (caused by old age) is considered to be associated with chronic ischaemia and inflammation. | 22641456 |
| Inflammation | Altered Intercellular Communication | CRP association with ICT/SEC suggests that inflammation plays a role in ICT/SEC formation. | 22641545 |
| Blood Clot, Thrombophilia | Altered Intercellular Communication | Intra-cardiac thrombus (ICT) and spontaneous echo contrast (SEC) are considered hypercoagulable and inflammatory conditions. | 22641545 |
| Inflammation, Postthrombotic Syndrome | Altered Intercellular Communication | Markers of coagulation, fibrinolysis and inflammation in relation to post-thrombotic syndrome. | 22642402 |
| Inflammation, Thrombophilia | Altered Intercellular Communication | Persistent inflammation rather than hypercoagulability might be the most important etiological factor in PTS, and may be a target for future therapy. | 22642402 |
| Inflammation, Endothelial dysfunction, Atherosclerosis | Altered Intercellular Communication | YKL-40, a proposed marker of inflammation and endothelial dysfunction, is associated with atherosclerosis and an increased cardiovascular mortality in the general population. | 22642467 |
| Inflammation, Scleritis, Episcleritis | Altered Intercellular Communication | Initial inflammation control was achieved in 78-81% of scleritis patients and 73-80% episcleritis patients on COXIs (p > .05). | 22642498 |
| Abdominal Cramps | Altered Intercellular Communication | The relationship between abdominal cramps and hot flushes may be hormonal or sociocultural. | 22642878 |
| Meningioma, Hormone abnormality, Visual disturbance | Altered Intercellular Communication | Sellar meningiomas are technically challenging and carry a high risk for visual disturbance and pituitary hormonal abnormalities. | 22644157 |
| Adult Non-Hodgkin Lymphoma, Pseudolymphoma, Immunoglobulin G4-Related Disease, Orbital Pseudotumor | Altered Intercellular Communication | The breakdown of the 71 cases was: 45 cases of non-Hodgkin lymphoma, 16 cases of IgG4-ROD, 5 cases of reactive lymphoid hyperplasia, and 5 cases of idiopathic orbital inflammation. | 22644450 |
| Inflammatory Bowel Diseases, Inflammation, Weight decreased, Ulceration, CTCAE | Altered Intercellular Communication | This study reports the case of a 15-year-old male patient with extensive anal inflammation, cobblestone-like mucosa and areas of ulceration, loose bloody stool and weight loss for 8 weeks, suggestive of inflammatory bowel disease. | 22645392 |
| Chronic lymphocytic inflammation, Pontine structure | Altered Intercellular Communication | Chronic lymphocytic inflammation with pontine perivascular enhancement responsive to steroids following influenza vaccination. | 22646278 |
| Chronic lymphocytic inflammation, Pontine structure, Clippers | Altered Intercellular Communication | We present the case of a patient with a newly described inflammatory process that primarily involves the pons and adjacent structures, which is called chronic lymphocytic inflammation with pontine perivascular enhancement responsive to steroids (CLIPPERS). | 22646278 |
| Inflammation, Edema, Pain Distress Question | Altered Intercellular Communication | Complications such as mild edema, inflammation and pain were noted in three patients, which resolved within few days. | 22646527 |
| Presenile dementia, Inflammation, "Alzheimers Disease", Data types - Address | Altered Intercellular Communication | Inflammation has been associated with Alzheimer's disease (AD) and dementia. | 22647255 |
| Angiodysplasia, Inflammation | Altered Intercellular Communication | There are a variety of additional endoscopic IRC therapeutic utilities: endoscopic management of angiodysplasia, inflammation, hemostasis, and NOTES applications. | 22648099 |
| Hepatic inflammation, Hepatocarcinogenesis | Altered Intercellular Communication | Dietary long-chain fatty acid (LCFA) intake is an important risk factor for hepatic inflammation and hepatocarcinogenesis. | 22648712 |
| PHB2 gene, Communicable Diseases, Inflammation, Arthritis, Reactive | Altered Intercellular Communication | Reactive arthritis (ReA) is a sterile joint inflammation triggered by a remote infection and associated with human leucocyte antigen (HLA)-B27. | 22651550 |
| Inflammation, Atherosclerosis | Altered Intercellular Communication | Inflammation is a pivotal process in the progression of atherosclerosis, which can be noninvasively imaged by FDG positron emission tomography (FDG-PET). | 22651864 |
| Eosinophilic cystitis | Altered Intercellular Communication | Eosinophilic cystitis is an inflammatory condition characterized by eosinophilic infiltration of whole layers of the bladder wall. | 22652390 |
| Inflammation, Anterior nares | Altered Intercellular Communication | The elevated levels of proinflammatory cytokines in NARES may indicate the chronic, self-perpetuating process of inflammation in NARES which seems to be more pronounced than in PAR. | 22652688 |
| Inflammation | Altered Intercellular Communication | Neutrophil gelatinase-associated lipocalin (NGAL), a protein involved in iron handling, has been recognized as a marker of inflammation. | 22652747 |
| Airway structure, Asthma | Altered Intercellular Communication | In asthmatic patients there is a relationship between EBC pH, ammonia and nitrite/nitrate concentrations and other recognized markers of airway inflammation. | 22653320 |
| Inflammation, Metabolic Diseases, Atherogenesis, Hypertension, CTCAE, Diabetes Mellitus, Non-Insulin-Dependent | Altered Intercellular Communication | It is thought that chronic inflammation results in metabolic diseases and proinflammatory cytokines give rise to the development of atherogenesis, peripheral insulin resistance, hypertension, and type 2 diabetes. | 22654590 |
| Pneumonitis, Neutrophil Infiltration | Altered Intercellular Communication | This Th2 bias and the eosinophilic reaction could be prevented by adding CpG to the vaccine formulation, which, however did not prevent pulmonary inflammation and neutrophil infiltration upon viral challenge. | 22655066 |
| Craniocerebral Trauma, Inflammation, Intracranial Hemorrhage, Meningitis, Chronic infectious disease, Traumatic injury, Pacchionian granulation | Altered Intercellular Communication | After tegmen dehiscence repair, ventriculoperitoneal shunting should be considered for patients with any combination of the following high-risk factors for recurrence: spontaneous CSF leak not caused by another predisposing condition (that is, trauma, chronic infections, or prior surgery), high-volume leaks, CSF opening pressure > 20 cm H(2)O, BMI > 30 kg/m(2), preoperative imaging demonstrating additional cranial base cortical defects (that is, contralateral tegmen or anterior cranial base) and/or an empty sella turcica, and any history of an event that leads to inflammation of the arachnoid granulations and impairment of CSF absorption (that is, meningitis, intracranial hemorrhage, significant closed head injury, and so forth). | 22655695 |
| Inflammation, Chronic heart failure, Congestive heart failure | Altered Intercellular Communication | Increasing evidences have been obtained that immune activation and inflammation play critical roles in the pathogenesis of chronic heart failure (CHF). | 22655909 |
| Refractory anemias, Inflammation | Altered Intercellular Communication | It is, therefore, hypothesized that synovial TRAF6 is involved in the pathogenesis of synovial inflammation and osteoclast differentiation in RA. | 22656185 |
| Tumor necrosis | Altered Intercellular Communication | Tumor necrosis factor receptor-associated factor 6 (TRAF6) is one of the critical mediators both in inflammatory signal pathway and differentiation and resorption activity of osteoclasts. | 22656185 |
| Communicable Diseases, Inflammation | Altered Intercellular Communication | The number of dressing changes, incidence of blistering, leakage, appearance of inflammation, infection rate and the average stay in hospital was recorded for each patient. | 22658450 |
| Inflammation | Altered Intercellular Communication | The rate of inflammation and average length of stay in hospital was not significantly different between the two groups. | 22658450 |
| Inflammation | Altered Intercellular Communication | Surgical stress may cause excessive inflammation and lead to microcirculatory dysfunction. | 22658494 |
| Inflammation, Carotid Intima-Media Thickness | Altered Intercellular Communication | Low plasma testosterone and elevated carotid intima-media thickness: importance of low-grade inflammation in elderly men. | 22658553 |
| Inflammation | Altered Intercellular Communication | In elderly men, low plasma testosterone is associated with elevated carotid intima-media thickness only in those with low-grade inflammation. | 22658553 |
| palladium, Inflammation | Altered Intercellular Communication | The C8orf4 gene had small p values for both motor and cognitive outcomes, highlighting inflammation as a possible pathogenesis mechanism for progression in PD. | 22658654 |
| Inflammation, Neoplasms | Altered Intercellular Communication | Apart from previously recognized factors, such as histosubtype, tumor stage, and hemoglobin level difference, NLR, an index of systemic inflammation bears prognostic significance that shows that a snapshot of immune status is able to convey important prognostic information. | 22658812 |
| Inflammation, Etiology aspects, Colitis | Altered Intercellular Communication | "Pseudomembranous collagenous colitis" is a morphologic variant of collagenous colitis in which active inflammation with pseudomembrane formation is prominent and which has been associated with infectious, toxic, and ischemic etiologies. | 22658854 |
| Inflammation, Chronic Obstructive Airway Disease | Altered Intercellular Communication | Bronchodilators modulate inflammation in chronic obstructive pulmonary disease subjects. | 22659487 |
| ARCN1 gene, Chronic Obstructive Airway Disease, Airway structure | Altered Intercellular Communication | Chronic obstructive pulmonary disease (COPD) is characterized by neutrophilic airway inflammation and oxidative stress. | 22659487 |
| Inflammation, Adolescence | Altered Intercellular Communication | From infancy to adolescence, critical illness seems to be a major determinant of midazolam clearance, which may result from reduced CYP3A4/5 activity due to inflammation. | 22660604 |
| Cartilage destruction, Inflammation, Refractory anemias | Altered Intercellular Communication | The positive association between S-COMP and ACPA suggests that these factors might interact, and could both be contributors to an unknown link between inflammation and cartilage destruction in patients with RA. | 22660798 |
| Airway structure, Rheumatoid Arthritis, Pulmonary Fibrosis | Altered Intercellular Communication | Improvements in cystic fibrosis lung disease and airway inflammation associated with etanercept therapy for rheumatoid arthritis: a case report. | 22660986 |
| TNF protein, human, Inflammation, Fibrosis Assessment, Tumor necrosis | Altered Intercellular Communication | Cystic fibrosis (CF) lung pathology is characterized by excessive neutrophilic inflammation and high tumor necrosis factor-alpha (TNF-a) levels. | 22660986 |
| Inflammation, Crohn Disease | Altered Intercellular Communication | To compare quantified terminal ileal (TI) motility during MR enterography (MRE) with histopathological severity of acute inflammation in Crohn's disease. | 22661057 |
| Inflammation | Altered Intercellular Communication | Wilcoxon rank sum test compared motility in subjects with and without histopathological inflammation. | 22661057 |
| Inflammation, Ischemia | Altered Intercellular Communication | New vessel formation contributes to organ development during embryogenesis and tissue repair in response to mechanical damage, inflammation, and ischemia in adult organisms. | 22661514 |
| Nephritis, Chronic Kidney Diseases | Altered Intercellular Communication | Indomethacin reduces glomerular and tubular damage markers but not renal inflammation in chronic kidney disease patients: a post-hoc analysis. | 22662255 |
| Airway structure, ARCN1 gene, Asthma | Altered Intercellular Communication | Sputum induction can be used as a non-invasive technique to investigate airway inflammation in asthma and COPD. | 22662642 |
| Inflammation, Fibrosis Assessment | Altered Intercellular Communication | Transbronchial lung biopsy revealed interstitial fibrosis, chronic inflammation and iron deposits. | 22662643 |
| Inflammation, Perforation (observation) | Altered Intercellular Communication | In the 4 months after the procedure, chronic inflammation of the retroperitoneal space caused a further perforation on the posterior wall of the aorta in the area of the bifurcation, distal to the graft. | 22664288 |
| Inflammation, Hyperplastic Polyp, atherosclerotic | Altered Intercellular Communication | The aim was to assess the release of MP and its association with inflammation and atherosclerotic burden. | 22664782 |
| Inflammation, ruptured disk, Hernia | Altered Intercellular Communication | Several possible aetiologies are also suggested, with disc rupture and inflammation followed by disc resorption and dural pocket formation being a possible mechanism predisposing to herniation at the extreme end of a clinicopathological spectrum. | 22665931 |
| Inflammation | Altered Intercellular Communication | Inflammation is a primary contributor to graft loss, and inhibiting pro-inflammatory cytokine activity can reverse inflammation mediated dysfunction of islet grafts. | 22666480 |
| Inflammation, atherosclerotic | Altered Intercellular Communication | Inflammation plays a crucial role in the progression of atherosclerotic plaques. | 22669090 |
| Inflammation, Fibrosis Assessment | Altered Intercellular Communication | There were non-significant decreased risks with finasteride use (OR(adj advanced fibrosis) = 0.75, 95 % CI 0.39-1.45 and OR(adj advanced inflammation) = 0.74, 95 % CI 0.41-1.43). | 22669204 |
| Inflammation | Altered Intercellular Communication | White male methadone-users had 2.1-fold excess advanced inflammation risk (p = 0.15). | 22669204 |
| Inflammation, Fibrosis Assessment | Altered Intercellular Communication | Our preliminary study results suggest finasteride use is not significantly associated with a decreased risk of advanced hepatic fibrosis or inflammation in HCV+ males. | 22669204 |
| Inflammation, Fibrosis Assessment | Altered Intercellular Communication | The ethnically-divergent results for methadone associated fibrosis risk and finding of potentially increased inflammation risk in White males suggests the need for additional research. | 22669204 |
| Inflammation, Malignant Neoplasms | Altered Intercellular Communication | The histopathology report suggested inflammation with no evidence of malignancy. | 22669871 |
| Inflammation, Traumatic injury | Altered Intercellular Communication | No history of trauma was noted and he was systemically well with no clinical signs of acute inflammation. | 22669928 |
| polychondritis, Sweet Syndrome | Altered Intercellular Communication | Relapsing polychondritis and Sweet's syndrome are rare systemic inflammatory conditions. | 22670004 |
| Inflammation, diabetic | Altered Intercellular Communication | Within the limits of this study, our preliminary findings indicate that periodontal inflammation may influence circulating and GCF substance P levels in poorly controlled diabetic subjects. | 22670254 |
| Inflammation, Seborrheic dermatitis of scalp | Altered Intercellular Communication | Induced inflammatory genes were also enriched in dandruff uninvolved skin, suggesting the existence of predisposing factors associated with inflammation. | 22670617 |
| Inflammation | Altered Intercellular Communication | Systemic inflammation worsens outcomes in emergency surgical patients. | 22673238 |
| Inflammation | Altered Intercellular Communication | For surgeons whose practice is mostly elective, the significance of such systemic inflammation may be underappreciated. | 22673238 |
| Inflammation | Altered Intercellular Communication | This study sought to determine the influence of preoperative systemic inflammation on postoperative outcome in patients requiring emergent colon surgery. | 22673238 |
| Sepsis, Inflammation, Systemic Inflammatory Response Syndrome, Septic Shock | Altered Intercellular Communication | Four groups were defined by the presence and magnitude of the inflammatory response before operation: no inflammation, systemic inflammatory response syndrome (SIRS), sepsis, or severe sepsis/septic shock. | 22673238 |
| Inflammation | Altered Intercellular Communication | Thirty-day survival was significantly different (p < 0.0001) among the four groups; increasing magnitudes of preoperative inflammation had increasing probability of mortality (p < 0.0001). | 22673238 |
| Inflammation, Sepsis, Systemic Inflammatory Response Syndrome, Septic Shock, Cessation of life | Altered Intercellular Communication | Hazard ratios indicated that, compared with patients without preoperative systemic inflammation, the relative risk of death from SIRS was 1.9 (p < 0.0001), from sepsis was 2.5 (p < 0.0001), and from severe sepsis/septic shock was 6.7 (p < 0.0001). | 22673238 |
| Inflammation | Altered Intercellular Communication | Functional polymorphic sites in the promoter region of FCN1 regulate both the expression and synthesis of ficolin-1 and are associated with outcome in severe inflammation. | 22673311 |
| Inflammation, Ectopic ureter, Paratesticular mass | Altered Intercellular Communication | The patient was treated successfully with a radical orchiectomy and found to have ureteral ectopia inserting into the ipsilateral epididymis, resulting in this paratesticular mass caused by inflammation of the epididymis. | 22673544 |
| Inflammation | Altered Intercellular Communication | It is characterised by inflammation of the small blood vessels leading to damage in any number of organs. | 22673710 |
| Compression, Acute inflammation, Cleaved | Altered Intercellular Communication | Internal compression of the cleft by the haptic of a normal sized IOL along with postoperative inflammation led to scarring and closure of the cleft. | 22673716 |
| Inflammation | Altered Intercellular Communication | Ten weeks after the last injection, cartilage matrix turnover and synovial inflammation were analyzed. | 22674062 |
| Inflammation | Altered Intercellular Communication | Synovial inflammation was present only after intraarticular injections with coagulating blood. | 22674062 |
| Inflammation, Small vessel vasculitis, Myalgia, CTCAE 5 | Altered Intercellular Communication | Primary small vessel vasculitis of the skeletal muscle should be considered in patients presenting with myalgia and signs of systemic inflammation in the absence of other organ manifestations. | 22674106 |
| Airway structure, Sleep Apnea, Obstructive | Altered Intercellular Communication | Analysis of systemic and airway inflammation in obstructive sleep apnea. | 22674397 |
| Airway structure, Sleep Apnea, Obstructive, Osage language | Altered Intercellular Communication | The presence of both systemic and airway inflammation has been suggested in obstructive sleep apnea (OSA) by increased levels of inflammatory biomarkers in the circulation and respiratory specimens. | 22674397 |
| Airway structure, Osage language | Altered Intercellular Communication | We aimed to investigate the relationship between systemic and airway inflammation in OSA. | 22674397 |
| Airway structure, Morbid obesity, Osage language | Altered Intercellular Communication | Systemic and airway inflammation in OSA might be differently regulated by OSA itself and comorbid obesity, depending on the type of cytokine. | 22674397 |
| Inflammation, HIV-1 Infection Pathway | Altered Intercellular Communication | We also saw a gradual decline of the CD4+T cell count, widespread immune activation, up-regulation of inflammation marker and microbial translocation after HIV-1 infection. | 22675567 |
| Inflammation, Chronic sinusitis, Craniosynostosis | Altered Intercellular Communication | Chronic rhinosinusitis (CRS) is a disease characterized by inflammation of the nasal mucosa and paranasal sinuses. | 22676062 |
| Inflammation, Fungal Colonization | Altered Intercellular Communication | This inflammation may result in part from decreased epithelial barrier and innate immune responses, leading to frequent bacterial and fungal colonization. | 22676062 |
| Inflammation, Obesity | Altered Intercellular Communication | Increased MIF concentrations were associated with increased markers of inflammation and obesity. | 22676646 |
| Inflammation, Obesity | Altered Intercellular Communication | Taken together with other markers, this indicates the presence of low-grade inflammation in these young subjects, possibly representing a link between obesity and related co-morbidities. | 22676646 |
| Liver carcinoma | Altered Intercellular Communication | An inflammation-based prognostic index predicts survival advantage after transarterial chemoembolization in hepatocellular carcinoma. | 22677364 |
| Inflammation, Atherosclerosis | Altered Intercellular Communication | No sign of atherosclerosis or inflammation was detected. | 22678132 |
| Airway structure, Asthma, Respiratory Hypersensitivity, Obesity | Altered Intercellular Communication | Obesity is a risk factor for asthma in the general population, but the effect of obesity on airway hyperresponsiveness (AFHR) or airway inflammation in asthma is not clear. | 22678356 |
| Kidney Failure, Chronic | Altered Intercellular Communication | Low free triiodothyronine (fT3) has been associated with the presence of malnutrition-inflammation syndrome in patients with end-stage renal disease (ESRD) and decreased overall survival in ESRD. | 22678525 |
| Abscess of aortic root | Altered Intercellular Communication | After careful consideration, it is likely that what was thought to be an aortic root abscess was instead an area of perivalvular inflammation. | 22678733 |
| Inflammation | Altered Intercellular Communication | Perivascular inflammation may have an important role in the processes of vascular remodeling, all of which may ultimately lead to increased pulmonary artery pressure. | 22679007 |
| ARCN1 gene, Inflammation, Mast cell infiltration, Pulmonary Emphysema, Hyperreactivity | Altered Intercellular Communication | Hence, we investigated mast cell infiltration, along with overall inflammation, and their relation with hyperreactivity and emphysema type in COPD. | 22679009 |
| Inflammation, Pulmonary Emphysema, Alveolar wall | Altered Intercellular Communication | We studied lung function, emphysema type, mast cells, and overall inflammation in small airways and alveolar walls, along with alveolar wall thickening in 67 subjects undergoing lung resection (59 smokers, 8 nonsmokers). | 22679009 |
| ARCN1 gene, Inflammation | Altered Intercellular Communication | The pathological phenotypes of COPD CLE and PLE show important differences in their overall inflammation with a protagonism of mast cells, which are related to airway reactivity. | 22679009 |
| Inflammation, Inflammatory colitis | Altered Intercellular Communication | Colonoscopy demonstrated inflammation up to the splenic flexure and histology confirmed inflammatory colitis. | 22679163 |
| Inflammation, Cronkhite-Canada Syndrome, Edema | Altered Intercellular Communication | Biopsies showed cystic glandular dilatation, lamina propria oedema and chronic inflammation consistent with Cronkhite-Canada syndrome (CCS). | 22679262 |
| Inflammation, ciliary vesicle | Altered Intercellular Communication | Inflammation in early life may play a causal role in the adult association between short LTL and CV disease. | 22679311 |
| Inflammation | Altered Intercellular Communication | It is characterised by inflammation, increased deposition of submucosal collagen and formation of fibrotic bands in the oral and paraoral tissues, which increasingly limit mouth opening. | 22679326 |
| Inflammation, Coronary heart disease | Altered Intercellular Communication | [Effects of naoxintong capsule on the inflammation and prognosis in borderline lesion coronary heart disease patients]. | 22679718 |
| Inflammation, Fibrosis Assessment, Diverticular Diseases | Altered Intercellular Communication | Inflammation may be detected in diverticular disease (DD), and fibrosis may also develop. | 22680042 |
| Weight Gain | Altered Intercellular Communication | Other important morbidities were persistent hormonal disturbances and weight gain. | 22680243 |
| Granuloma, Periodontitis, Inflammation | Altered Intercellular Communication | The presence of granuloma in apical periodontitis (AP) is linked with inflammation and the synthesis of metabolites of AA. | 22682033 |
| Immunologic Deficiency Syndromes, Qualitative abnormality of granulocyte, Cystic Fibrosis | Altered Intercellular Communication | Currently it is thought more likely that the following factors are involved: progressive increase in dilatation of small bronchi, delayed diagnosis, morphological abnormalities of the thorax, hormonal factors, immune deficiency, genetic neutrophil dysfunction, and even heterozygous forms of cystic fibrosis. | 22682598 |
| Inflammation, anatomical bulb | Altered Intercellular Communication | Slit-lamp examination performed 2 weeks later showed severe inflammation and areas of ulceration along all 4 lids and complete, bilateral sloughing of bulbar and palpebral conjunctivae, including the limbus. | 22683916 |
| Obstructive chronic pancreatitis, Inflammation, Primary | Altered Intercellular Communication | Stenosis of the pancreaticoenterostomy induces obstructive chronic pancreatitis, which occurs due to primary stenosis or obstruction of the main pancreatic duct and causes in inflammation of the distal pancreas. | 22683982 |
| Inflammation, Sleeplessness, Coronary heart disease | Altered Intercellular Communication | Our results do not support the hypothesis that inflammation, as reflected by elevated levels of hsCRP, is an important factor linking insomnia to coronary heart disease. | 22685243 |
| ARCN1 gene, Inflammation, Chronic Obstructive Airway Disease | Altered Intercellular Communication | Delayed neutrophil apoptosis may be an important factor in the persistent inflammation associated with chronic obstructive pulmonary disease (COPD). | 22686245 |
| Inflammation, Anemia, Kidney Diseases | Altered Intercellular Communication | Major causes of persistent or recurrent anemia at follow up were renal disease (62%) and chronic inflammation (35%). | 22686591 |
| Intraocular inflammation | Altered Intercellular Communication | Subjects who received bevacizumab were 12 times more likely to develop severe intraocular inflammation following each injection than were those who received ranibizumab (OR = 11.71; 95% CI 1.5-93). | 22687306 |
| Unspecified visual loss | Altered Intercellular Communication | The 1 case of acute intraocular inflammation following ranibizumab injection was mild and not associated with vision loss. | 22687306 |
| Pheochromocytoma, Mass of pancreas | Altered Intercellular Communication | Imaging revealed a pancreatic mass with biliary and pancreatic ductal dilatation and a hormonal assay led to the diagnosis of functional pheochromocytoma. | 22687375 |
| Inflammation, Atherosclerosis | Altered Intercellular Communication | Effect of rosuvastatin on ROCK activity, endothelial function, and inflammation in Asian patients with atherosclerosis. | 22687786 |
| Renal Insufficiency, Inflammation, Hematuria, CTCAE | Altered Intercellular Communication | When hematuria was first discovered in 2008, renal dysfunction [creatinine (Cr), 1.2 mg/dL], inflammation [C-reactive protein (CRP), 12 mg/dL] and high myeloperoxidase anti-neutrophil cytoplasmic antibodies (MPO-ANCA) levels [546 ELISA units (EU)] were observed. | 22687795 |
| Inflammation | Altered Intercellular Communication | Chronic inflammation and long-term changes in expression of cytokines and growth factors after GKS may have triggered this case. | 22688073 |
| Inflammation, Diabetic foot ulcer, Failure (biologic function) | Altered Intercellular Communication | We examined the role of vascular function and inflammation in the development and failure to heal diabetic foot ulcers (DFUs). | 22688339 |
| Inflammation, Failure (biologic function) | Altered Intercellular Communication | We conclude that increased inflammation, expression of MMP-9, PTP1B, and aberrant growth factor levels are the main factors associated with failure to heal DFUs. | 22688339 |
| Inflammation, Fracture, Traumatic injury | Altered Intercellular Communication | Quantification of surgical trauma: comparison of conventional and minimally invasive surgical techniques for pertrochanteric fracture surgery based on markers of inflammation (interleukins). | 22688402 |
| Inflammation, Diabetes Mellitus, Non-Insulin-Dependent | Altered Intercellular Communication | Reduction of oxidative stress and inflammation by blunting daily acute glucose fluctuations in patients with type 2 diabetes: role of dipeptidyl peptidase-IV inhibition. | 22688551 |
| Inflammation, Diabetes Mellitus, Non-Insulin-Dependent | Altered Intercellular Communication | MAGE reduction is associated with reduction of oxidative stress and markers of systemic inflammation in type 2 diabetic patients. | 22688551 |
| Hepatic inflammation | Altered Intercellular Communication | We investigated whether reduced hepatic inflammation was associated with clinical benefit in 834 patients with a baseline and follow-up biopsy 1.5 years after randomization to peginterferon or observation. | 22688849 |
| MS gene, Inflammation, White matter lesions | Altered Intercellular Communication | In multiple sclerosis (MS), gray matter pathology is characterized by less pronounced inflammation when compared with white matter lesions. | 22689449 |
| Inflammation, Fibrosis Assessment | Altered Intercellular Communication | Liver biopsy showed macrovesicularsteatosis without fibrosis or inflammation. | 22689598 |
| Inflammation, Metabolic Syndrome X, Chronic Kidney Diseases | Altered Intercellular Communication | Low-grade inflammation, metabolic syndrome and the risk of chronic kidney disease: the 2005 Korean National Health and Nutrition Examination Survey. | 22690094 |
| Renal Insufficiency, Inflammation, Metabolic Syndrome X, ETV3 wt Allele | Altered Intercellular Communication | Either chronic inflammation or metabolic syndrome (MetS) is associated with renal impairment. | 22690094 |
| Inflammation, Chronic Kidney Diseases, ETV3 wt Allele | Altered Intercellular Communication | Low-grade inflammation is significantly associated with CKD stage 3 or more in subjects with MetS but not in those without MetS. | 22690094 |
| Neurogenic Inflammation, Otitis Media with Effusion | Altered Intercellular Communication | The etiology of OME is multifactorial, and neurogenic inflammation may play a significant role. | 22691066 |
| Asthma, allergic inflammation | Altered Intercellular Communication | Airways allergic inflammation and L. reuterii treatment in asthmatic children. | 22691248 |
| allergic inflammation | Altered Intercellular Communication | Recently, it has been hypothesized that the oral administration of specific live probiotic strains may have therapeutic potential in the treatment of allergic inflammation. | 22691248 |
| Asthma, Bronchitis | Altered Intercellular Communication | In conclusion, these data showed that L. reuteri (108 CFU) was effective in reducing bronchial inflammation in asthmatic children. | 22691248 |
| Alzheimers Disease", Data types - Address | Altered Intercellular Communication | The cholinergic and glutamatergic neurotransmission systems are known to be severely disrupted in Alzheimer's disease (AD). | 22691495 |
| Inflammation, Pilomatrixoma | Altered Intercellular Communication | Pilomatricoma is uncommon in adults and an unusual cause for marked FDG uptake, likely due to foreign body inflammation. | 22691514 |
| Inflammation | Altered Intercellular Communication | This translational study opens new avenue to investigate ocular surface disorders by focusing on chemokine-related inflammation and immune cell trafficking in the ocular conjunctival mucosa. | 22692452 |
| Immune System Diseases | Altered Intercellular Communication | Inappropriate expression of the chemokine CX3CL1 is reportedly known to act on inflammatory conditions in extraocular immune diseases. | 22692452 |
| Inflammation, Atherosclerosis, Cardiovascular Diseases | Altered Intercellular Communication | Chronic inflammation promotes atherosclerosis in cardiovascular disease and is a major prognostic factor for patients undergoing percutaneous coronary intervention (PCI). | 22693633 |
| Inflammation | Altered Intercellular Communication | The results failed to support that an Er:YAG laser may be superior to conventional debridement in the treatment of smokers with recurring chronic inflammation. | 22694321 |
| Inflammation | Altered Intercellular Communication | This appears to be the first time that repeated Er-YAG laser instrumentation has been compared with mechanical instrumentation of periodontal sites with recurring chronic inflammation over a clinically relevant time period. | 22694321 |
| vascular inflammations, Diabetes Mellitus | Altered Intercellular Communication | These results suggest inhibition of Rho/ROCK signaling may have therapeutic potential in preventing diabetes associated vascular inflammation and atherogenesis. | 22694757 |
| Myocarditis | Altered Intercellular Communication | Both the non-IMID and IMID DCM patients demonstrated increased myocardial inflammation compared to controls: 12.5 +- 1.8 and 14.0 +- 3.2 CD45-positive inflammatory cells, respectively, versus 5.1 +- 0.7 for the controls (P < 0.05 for both). | 22695157 |
| Inflammation | Altered Intercellular Communication | Histology results from the liver and omentum revealed necrotising granulomatous inflammation suggestive of TB. | 22696746 |
| Hepatitis C, Chronic, Hepatitis | Altered Intercellular Communication | Extent of liver inflammation in predicting response to interferon a & Ribavirin in chronic hepatitis C patients: a cohort study. | 22697612 |
| Carcinogenic Chlorinated Hydrocarbon, Fibrosis Assessment, Hepatitis C, Hepatitis | Altered Intercellular Communication | Liver inflammation due to HCV infection leads to fibrosis, which is an independent predictor of treatment response to interferon therapy in Chronic Hepatitis C (CHC) patients. | 22697612 |
| Hepatitis | Altered Intercellular Communication | ALT is a less invasive test than liver biopsy for measuring liver inflammation. | 22697612 |
| Hepatitis | Altered Intercellular Communication | Diagnostic accuracy of pretreatment ALT for liver inflammation grades was determined by computing Area Under the Receiver Operator Curve (AUROC). | 22697612 |
| Hepatitis | Altered Intercellular Communication | Among them, 103 had high and 569 had low grades of liver inflammation. | 22697612 |
| Inflammation | Altered Intercellular Communication | Mean age was 36.9 (SD 9.1) years, with patients with high grades being older than those with low grades inflammation (p = 0.03). | 22697612 |
| Fibrosis, Liver, Hepatitis | Altered Intercellular Communication | High grades of liver inflammation was associated with ETR (RR 1.17, 95% CI 1.12-1.18) adjusting for age, Total Leukocyte count (TLC) and pretreatment levels of ALT, irrespective of liver fibrosis. | 22697612 |
| Inflammation | Altered Intercellular Communication | AUROC of pretreatment ALT for males and females was moderately accurate for severe inflammation compared to minimal inflammation and less accurate for high grades compared to low grades. | 22697612 |
| Fibrosis Assessment, Hepatitis, Liver Cirrhosis | Altered Intercellular Communication | ETR in patients with higher grades of liver inflammation was 17% higher than those with lower grades irrespective of fibrosis and 9% higher for bridging fibrosis and cirrhosis. | 22697612 |
| Inflammation | Altered Intercellular Communication | Pretreatment ALT was moderately accurate for severe inflammation only on liver biopsy in both males and females. | 22697612 |
| Inflammation, Observation Method - Coagulation | Altered Intercellular Communication | The biosynthetic interface between the patient and the circuit can significantly alter inflammation, coagulation, pharmacokinetics and disposition of trace elements. | 22697617 |
| Inflammation, Observation Method - Coagulation | Altered Intercellular Communication | We obtained preliminary data on inflammation, coagulation, histology, pharmacokinetics and trace element disposition during ECLS. | 22697617 |
| methyldopa, Inflammation, Age related macular degeneration | Altered Intercellular Communication | Oxidative stress and inflammation are known to be associated with age-related macular degeneration (AMD). | 22698681 |
| Inflammation, Brain Injuries, physiopathological | Altered Intercellular Communication | Cerebrospinal fluid markers of brain injury, inflammation, and blood-brain barrier dysfunction in cardiac surgery. | 22698770 |
| Inflammation | Altered Intercellular Communication | Cerebral microembolization, inflammation, blood-brain barrier (BBB) dysfunction, and impaired cerebral oxygenation are considered among possible etiologies. | 22698770 |
| Inflammation, Trauma, Nervous System, physiopathological, cell injury | Altered Intercellular Communication | Cardiac surgery with cardiopulmonary bypass causes cerebral inflammation, glial cell injury, and BBB dysfunction without biochemical signs of neuronal damage. | 22698770 |
| Inflammation | Altered Intercellular Communication | Inflammation induced by chemotherapy may contribute to hippocampal changes that underlie these deficits. | 22698992 |
| Inflammation, Cardiovascular Diseases | Altered Intercellular Communication | Experimental data suggested that MRP8/14 is important in the initiation and progression of inflammation and cardiovascular diseases. | 22699162 |
| Inflammation, Skin Angiosarcoma | Altered Intercellular Communication | Angiosarcoma of the scalp diagnosed by the presence of neck inflammation: a case report. | 22699262 |
| Inflammation, Skin Angiosarcoma | Altered Intercellular Communication | This article describes a rare case of angiosarcoma of the scalp, presenting as neck inflammation. | 22699262 |
| Pain Distress Question, Swelling, Neck Pain | Altered Intercellular Communication | Although patients generally describe pain and swelling at the primary lesion site, this patient complained only of painful neck inflammation, without any indication of pain or swelling of the scalp. | 22699262 |
| Inflammation, Diabetes Mellitus, Non-Insulin-Dependent, Blood Glucose | Altered Intercellular Communication | This novel IL-1b-neutralizing antibody improved glycemia, possibly via restored insulin production and action, and reduced inflammation in patients with type 2 diabetes. | 22699287 |
| Inflammation, Abnormality of the vasculature, Vascular Diseases | Altered Intercellular Communication | However, these vascular abnormalities are related to signs of systemic low grade inflammation, suggesting a common pathophysiological mechanism apparently present also in other vascular diseases but yet to be elucidated. | 22699414 |
| Hypotension, CTCAE, Inflammation | Altered Intercellular Communication | To evaluate the balance between arginine-vasopressin (AVP) and apelin during hemodialysis and its role in hypotension onset and in the inflammation status. | 22699819 |
| Inflammation, Tuberculosis | Altered Intercellular Communication | TEVAR was performed considering: (1) no preoperative ongoing inflammation, (2) no evidence of tuberculosis recurrence, and (3) risk factors, such as pulmonary impairments and high age. | 22700454 |
| Pneumonitis, alpha 1-Antitrypsin Deficiency | Altered Intercellular Communication | The variability of pulmonary inflammation in patients with a(1)-antitrypsin deficiency (A1ATD) is unknown. | 22700846 |
| Inflammation, Uveitis | Altered Intercellular Communication | Examination revealed perilimbal injection and anterior chamber inflammation in the left eye consistent with an anterior uveitis. | 22701003 |
| Hepatitis A, Inflammation | Altered Intercellular Communication | The rationale for seeking increased PA formation in chronic viral hepatitis is based on the involvement of activated macrophages in chronic viral hepatitis-associated inflammation. | 22701277 |
| Carcinogenic Chlorinated Hydrocarbon, Inflammation, Hepatitis C, Diabetes Mellitus | Altered Intercellular Communication | We assessed PA and high-sensitivity C-reactive protein (hsCRP) as a marker of inflammation in 51 patients with chronic hepatitis C infection (CHC), both with and without diabetes and 40 controls. | 22701277 |
| ARCN1 gene, Inflammation, Tissue injury | Altered Intercellular Communication | Systemic biomarkers of neutrophilic inflammation, tissue injury and repair in COPD patients with differing levels of disease severity. | 22701684 |
| Inflammation, Metabolic Diseases, Psoriasis | Altered Intercellular Communication | Both psoriasis and metabolic disorders are associated with systemic inflammation. | 22702656 |
| Immediate hypersensitivity, Data types - Address | Altered Intercellular Communication | IgE-mediated allergic inflammation may play an important role in the pathobiology of elderly AD, similar to other age groups of AD. | 22702954 |
| Idiopathic Inflammatory Myopathies, Paresis, Autoimmune reaction, Myositis | Altered Intercellular Communication | Idiopathic inflammatory myopathies (IIMs) are a rare group of autoimmune syndromes characterized by chronic muscle inflammation and muscle weakness with no known cause. | 22703603 |
| Inflammation | Altered Intercellular Communication | Endovascular repair for IAAA results in successful management with improvement of periaortic inflammation. | 22703973 |
| Inflammation, Pseudotumor, Necrosis | Altered Intercellular Communication | The resected mass consisted of necrotic tissue infiltrating inflammation cells, so it was diagnosed as pseudotumor. | 22704029 |
| Inflammation, vascular associated smooth muscle cell apoptotic process | Altered Intercellular Communication | Histologically AAAs are characterized by inflammation, vascular smooth muscle cell apoptosis, and extracellular matrix degradation. | 22704053 |
| Inflammation, Atherosclerosis | Altered Intercellular Communication | Stamp2 controls macrophage inflammation through nicotinamide adenine dinucleotide phosphate homeostasis and protects against atherosclerosis. | 22704678 |
| Inflammation | Altered Intercellular Communication | The six-transmembrane protein Stamp2 plays an important role in metabolically triggered inflammation and insulin action. | 22704678 |
| Diabetic Nephropathy, Inflammation | Altered Intercellular Communication | Chronic inflammation has emerged as being a key pathophysiology in the early stages of diabetic nephropathy. | 22705282 |
| Inflammation | Altered Intercellular Communication | YKL-40 has been established as an inflammatory marker in chronic inflammation. | 22705282 |
| Arterial Stiffness, Inflammation, Hypoxemia | Altered Intercellular Communication | If so, we examined the exaggeration of nocturnal hypoxemia and its related inflammation are related to this augmentation of increased arterial stiffness. | 22705293 |
| ARCN1 gene, Inflammation, Osage language, Hypoxemia, Arterial Stiffness | Altered Intercellular Communication | Thus, the overlap of COPD in patients with OSA augments increase in arterial stiffness without the exaggeration of nocturnal hypoxemia and inflammation. | 22705293 |
| Inflammation, Disease | Altered Intercellular Communication | Matrix metalloproteinase 9 (MMP-9) and the endogenous inhibitor to MMP-9, tissue inhibitor of metalloproteinase 1 (TIMP-1), have important roles in tissue remodelling and are implicated in a number of diseases related to inflammation. | 22706255 |
| Inflammation | Altered Intercellular Communication | Lipids which accumulate in the liver can stimulate inflammation, and the fatty acid derivatives, hydroxyeicosatetraenoic acids (HETEs) and hydroxyoctadecadienoic acids (HODEs), may play an important role in this process. | 22706383 |
| Inflammation, Diverticulitis | Altered Intercellular Communication | In most cases of diverticulitis, inflammation is mild, and the only treatment required is a clear liquid diet and antibiotics. | 22706731 |
| Nonalcoholic Steatohepatitis, Inflammation, Fatty degeneration, Non-alcoholic Fatty Liver Disease, Fatty Liver Disease | Altered Intercellular Communication | An algorithm for segregating lesions into normal liver, NAFLD, or nonalcoholic steatohepatitis (NASH) was built based on semiquantitative evaluation of steatosis, hepatocellular ballooning, and lobular inflammation. | 22707395 |
| Inflammation, Fatty Liver Disease | Altered Intercellular Communication | The activity score (ballooning + lobular inflammation) enabled discriminating NASH because all patients with NASH had A >= 2, whereas no patients with A < 2 had NASH. | 22707395 |
| ARCN1 gene, Inflammation, Chronic Obstructive Airway Disease, Cachexia | Altered Intercellular Communication | Systemic inflammation may contribute to cachexia in patients with chronic obstructive pulmonary disease (COPD). | 22708547 |
| ARCN1 gene, Inflammation, Cachexia, TNF protein, human | Altered Intercellular Communication | This study does not support the hypothesis that systemic inflammation is the cause of accelerated loss of fat free mass in COPD patients, but suggests a role for TNF-a in already cachectic COPD patients. | 22708547 |
| Inflammation, Hypertension, CTCAE | Altered Intercellular Communication | Arterial hypertension is characterised by increased oxidative stress and inflammation, which are associated with further cardiovascular risk. | 22708640 |
| Inflammation, Cytomegalovirus Infections | Altered Intercellular Communication | The age-related increase in low-grade systemic inflammation (Inflammaging) is not driven by cytomegalovirus infection. | 22708923 |
| Inflammation | Altered Intercellular Communication | Aging is accompanied by the development of low-grade systemic inflammation, termed 'inflammaging', characterized by raised serum C-reactive protein (CRP) and pro-inflammatory cytokines. | 22708923 |
| Presenile dementia, Diabetes Mellitus, Non-Insulin-Dependent, Cardiovascular Diseases | Altered Intercellular Communication | Importantly, inflammaging is implicated in the pathogenesis of several of the major age-related diseases including cardiovascular disease, type 2 diabetes, and dementia and is associated with increased mortality. | 22708923 |
| Inflammation, Cytomegalovirus Infections | Altered Intercellular Communication | The age-related increase in low-grade systemic inflammation (Inflammaging) is not driven by cytomegalovirus infection. | 22708923 |
| Inflammation | Altered Intercellular Communication | Aging is accompanied by the development of low-grade systemic inflammation, termed 'inflammaging', characterized by raised serum C-reactive protein (CRP) and pro-inflammatory cytokines. | 22708923 |
| Cytomegalovirus Infections, Inflammation | Altered Intercellular Communication | We conclude that CMV infection is not a primary causative factor in the age-related increase in systemic inflammation. | 22708923 |
| Inflammation | Altered Intercellular Communication | Chronic inflammation in older individuals is thought to contribute to inflammatory, age-related diseases. | 22708967 |
| Rosacea | Altered Intercellular Communication | Rosacea is a chronic inflammatory condition that affects the skin of the face and the eyes. | 22709541 |
| Inflammation, Neoplasms | Altered Intercellular Communication | CD8(+) T cells that produce interleukin (IL)-17 (Tc17 cells) promote inflammation and have been identified in tumors. | 22710190 |
| Inflammation, Data types - Address | Altered Intercellular Communication | The antioxidant vitamin complex was effective in reducing oxidative stress in PBMNC of AD patients by lowering ROS production, improving cellular antioxidant capacities and modifying cytokine induced inflammation. | 22710805 |
| Inflammation, Neoplasms | Altered Intercellular Communication | Focal inflammation around the tumor was observed at the exposed facial nerve. | 22711394 |
| Inflammation, Acute Coronary Syndrome | Altered Intercellular Communication | Osteopontin promotes inflammation in patients with acute coronary syndrome through its activity on IL-17 producing cells. | 22711477 |
| Acute Coronary Syndrome, Inflammation, GDC AJCC Clinical Stage Terminology | Altered Intercellular Communication | Here we confirm the existence of a critical imbalance in the ratio of Th17 to Treg-cell populations in peripheral CD4(+) T cells from patients with acute coronary syndrome (ACS), which favors inflammation. | 22711477 |
| Inflammation, GDC AJCC Clinical Stage Terminology | Altered Intercellular Communication | To our knowledge and beyond the disease context of ACS, this study constitutes the first demonstration of a critical role for OPN in the positive regulation of inflammation through increased IL-17 production by CD4(+) CD45RA(-) FOXP3(lo) cells. | 22711477 |
| Inflammation, Observation Method - Coagulation, Poor fine motor coordination | Altered Intercellular Communication | Inflammation, coagulation and risk of locomotor disability in elderly women: findings from the British Women's Heart and Health Study. | 22711587 |
| Inflammation, Observation Method - Coagulation, Poor fine motor coordination | Altered Intercellular Communication | This study investigated associations between chronic inflammation and coagulation and incident locomotor disability using prospective data from the British Women's Heart and Health Study. | 22711587 |
| Inflammation, Observation Method - Coagulation, Poor fine motor coordination | Altered Intercellular Communication | These results support the role of inflammation and coagulation in the development of locomotor disability in elderly women irrespective of their lifestyle factors and underlying age-related chronic diseases. | 22711587 |
| Renal Insufficiency, Inflammation, Pyelonephritis, Hydronephrosis | Altered Intercellular Communication | Bacterial inflammation was dominated symptom at the children with primary bacterial pyelonephritis, whereas children with hydronephrosis had low-grade clinical changes and significant renal functional impairment. | 22712303 |
| Inflammation, Dysplasia | Altered Intercellular Communication | The hystologic picture depends on lateralization of lesions: dysplasia of muscle layers is on the left side, mucous inflammation--on the right. | 22712303 |
| Sinusitis | Altered Intercellular Communication | Maxillary sinus inflammation, when untreated or incorrectly treated, may extend locoregionally, the remaining paranasal sinuses being the first affected anatomical structures. | 22712359 |
| helium, Inflammation | Altered Intercellular Communication | Laboratory indexes were obtained at the 30th, 60th, 90th days after gastric perfusion, which including state of mind, activity, fur, weight, joint swelling, largely image, hemorheology, inflammation and HE pathological appearance. | 22712380 |
| Degenerative polyarthritis, Inflammation, Cartilage injury | Altered Intercellular Communication | Knee osteoarthritis mainly show synovial inflammation at the early stage, inflammation at early stage is more severe than late; invigorating kidney and activating blood decoction can inhibit the knee cartilage injury, improve blood circulation and prevent local inflammatory reaction. | 22712380 |
| Toxic effect | Altered Intercellular Communication | Hyaluronidase toxicity: a possible cause of postoperative periorbital inflammation. | 22712486 |
| Inflammation, Allergy - Charge Type Reason | Altered Intercellular Communication | Periorbital inflammation following regional anaesthesia is commonly attributed to hyaluronidase allergy. | 22712486 |
| Cataract, Hypersensitivity, Toxic effect | Altered Intercellular Communication | Hyaluronidase toxicity, potentially related to concentration of hyaluronidase, may be a cause of postoperative periorbital inflammation after cataract surgery, rather than hypersensitivity. | 22712486 |
| Hypertension, CTCAE, Nephritis | Altered Intercellular Communication | Renal inflammation and oxidative stress are constantly present in experimental hypertension. | 22713485 |
| Stomach Carcinoma | Altered Intercellular Communication | Prognostic importance of the inflammation-based Glasgow prognostic score in patients with gastric cancer. | 22713657 |
| Neoplasms | Altered Intercellular Communication | The inflammation-based Glasgow prognostic score (GPS) has been shown to be a prognostic factor for a variety of tumours. | 22713657 |
| Inflammation, Carcinogenesis | Altered Intercellular Communication | A tissue microarray containing 115 core biopsies was constructed and stained for proteins involved in carcinogenesis, angiogenesis, inflammation, and cell-to-cell contact. | 22715107 |
| Inflammation, Carcinoma | Altered Intercellular Communication | We have demonstrated for the first time that proteins related to angiogenesis, inflammation, and cell proliferation are overexpressed in sebaceous gland carcinomas. | 22715107 |
| Inflammation, HIV Infections | Altered Intercellular Communication | Inflammation is a key feature of HIV infection and is correlated with long-term negative cardiovascular outcomes. | 22715361 |
| Limbic Encephalitis, Inflammation | Altered Intercellular Communication | In addition to temporal lobe involvement on the brain MRI and CSF inflammation, we propose EEG abnormalities as an additional diagnostic criterion for limbic encephalitis. | 22715483 |
| Low Vision, Orbital Pseudotumor | Altered Intercellular Communication | Despite an early response to treatment with intravenous amikacin, reactivation of left orbital inflammation led to eventual loss of vision. | 22715939 |
| Inflammatory abnormality of the eye | Altered Intercellular Communication | Regular ocular examinations revealed a mild to moderate transient ocular inflammation that resolved within 1 month of dosing in both species. | 22716662 |
| Inflammation, Dyslipidemias, Depression, CTCAE, Obesity, Anxiety Disorders | Altered Intercellular Communication | Increased dyslipidemia and (abdominal) obesity risk in patients with more severe anxiety disorders and depression may be partly explained by chronic low-grade inflammation and smoking. | 22717171 |
| Inflammation | Altered Intercellular Communication | Perioperative surgical outcomes, analgesic medication, and inflammation parameters were recorded. | 22717549 |
| Influenza-like illness, Heart failure, Myocarditis, CTCAE 5.0 | Altered Intercellular Communication | Myocarditis is defined as acute inflammation of the myocardium, usually following a non-specific flu-like illness, and encompasses a wide range of clinical presentations ranging from mild or subclinical disease to heart failure. | 22718060 |
| Hypocomplementemia, Interstitial inflammation | Altered Intercellular Communication | Immunological tests revealed hypocomplementemia, and the renal biopsy specimen showed diffuse interstitial inflammation. | 22718459 |
| Hypercholesterolemia, Inflammation | Altered Intercellular Communication | There is a relationship among hypercholesterolemia, oxidative stress and inflammation in the atherogenesis. | 22721254 |
| Lipemia - observation, Inflammation, physiopathological | Altered Intercellular Communication | Postprandial lipemia has been associated with inflammation, oxidative stress and vascular dysfunction. | 22721722 |
| Inflammation, Electrocardiogram: myocardial infarction (finding) | Altered Intercellular Communication | After adjustment for age and sex, RH-PAT was linked to condition, FFMI, myocardial infarction history, FEV(1), PaCO(2), heart rate, bicarbonates, inflammation and walking distance (p<0.10). | 22721944 |
| Inflammation, Endothelial dysfunction | Altered Intercellular Communication | Higher FFMI was associated with higher inflammation, oxidative stress and endothelial dysfunction. | 22721944 |
| Inflammation, Endothelial dysfunction, Diabetes Mellitus, Non-Insulin-Dependent, Vascular Diseases | Altered Intercellular Communication | NO-deficient states are characterized by cell senescence, oxidative stress, inflammation, endothelial dysfunction, vascular disease, insulin resistance and type 2 diabetes mellitus. | 22722323 |
| Conjunctivitis | Altered Intercellular Communication | At diagnosis, 64/163 (39%) eyes had moderate/severe conjunctival inflammation, and 102/164 (62%) had symblepharon formation. | 22722485 |
| Inflammation, Diabetes Mellitus, Non-Insulin-Dependent, Peripheral Neuropathy, Osage language | Altered Intercellular Communication | Because OSA is associated with inflammation and oxidative stress, we hypothesized that OSA is associated with peripheral neuropathy in type 2 diabetes. | 22723291 |
| Refractory anemias, Inflammation, Rheumatoid Arthritis, Tenosynovitis | Altered Intercellular Communication | To identify bilateral hand and wrist findings of synovial inflammation associated with progression to rheumatoid arthritis (RA) in very-early-RA cohort (VERA) (duration, <3 months) and early-RA cohort (ERA) (duration, <12 but >3 months), to test tenosynovitis as a magnetic resonance (MR) imaging additional parameter for improving diagnostic accuracy of the 2010 American College of Rheumatology/European League Against Rheumatism (ACR/EULAR) RA classification criteria, and to evaluate the symmetry of joint and tendon involvement. | 22723498 |
| Sialadenitis, Inflammation, Carcinoma, Structure of submaxillary duct, Malignant Neoplasms | Altered Intercellular Communication | Bilateral carcinoma in situ of Wharton's duct after chronic obstructive sialadenitis: inflammation as the cause of malignancy? | 22724274 |
| Inflammation, Malignant Neoplasms | Altered Intercellular Communication | We discuss etiologic factors and chronic inflammation as a possible cause of malignancy. | 22724274 |
| Inflammation, Gastrointestinal mucositis | Altered Intercellular Communication | Oral mucositis is a serious complication of chemotherapy that results in painful debilitating inflammation, necessitating the administration of analgesics. | 22724877 |
| Inflammation, Fibrosis Assessment, Fatty degeneration, Portal inflammation | Altered Intercellular Communication | We took specimens from three different parts of each liver and recorded the degrees of steatosis, hepatocyte ballooning, lobular inflammation, portal inflammation, and fibrosis. | 22724878 |
| Inflammation | Altered Intercellular Communication | Fibrosis[intra-class correlation (ICC) = 0.87], lobular inflammation (kappa = 0.83), and portal inflammation (kappa = 0.83)were fairly uniformly distributed in the damaged liver. | 22724878 |
| Sepsis, Inflammation | Altered Intercellular Communication | Plasma leukocyte cell-derived chemotaxin 2 is associated with the severity of systemic inflammation in patients with sepsis. | 22725643 |
| Inflammatory disorder | Altered Intercellular Communication | The aim of the present study was to determine the correlations between leukocyte cell-derived chemotaxin 2 (LECT2) and inflammation-related variables in human inflammatory disease. | 22725643 |
| Sepsis, Inflammation | Altered Intercellular Communication | Thus, the LECT2 concentration correlates with the severity of systemic inflammation in patients with sepsis. | 22725643 |
| Hyperglycemia, Impaired T cell function, Diabetes Mellitus, Non-Insulin-Dependent | Altered Intercellular Communication | Evaluate anti-interleukin-1b (IL-1b) antibody, canakinumab, in patients with type 2 diabetes and impaired glucose tolerance (IGT) in whom hyperglycaemia may trigger IL-1b-associated inflammation leading to suppressed insulin secretion and b-cell dysfunction. | 22726220 |
| Inflammation, Ulcerative Colitis | Altered Intercellular Communication | Comparative analysis of inflamed and non-inflamed colon biopsies reveals strong proteomic inflammation profile in patients with ulcerative colitis. | 22726388 |
| Inflammation, Bulla, Autoimmune Disorder, CTCAE | Altered Intercellular Communication | Mucous membrane pemphigoid (MMP) is an autoimmune blistering disorder characterized by inflammation, blistering, and scarring and predominantly occurring at mucous membranes. | 22727107 |
| Inflammation | Altered Intercellular Communication | Whereas with the PI no difference between the two groups was found (p = 0.9), the ACS-group showed significantly more signs of inflammation (GI) than the H-group (p = 0.045). | 22727119 |
| Inflammation, Tooth Loss, GDC AJCC Clinical Stage Terminology | Altered Intercellular Communication | Although, the state of oral health of the ACS-group differed only insignificantly from that of control, patients with ACS showed more signs of gingival inflammation and a higher loss of teeth. | 22727119 |
| Inflammation, Neuralgia, Leprosy | Altered Intercellular Communication | It can be nociceptive due to tissue inflammation occurring during episodes of immune mediated reactions, or neuropathic due to leprosy affecting the somatosensory system. | 22727538 |
| Inflammation, Primary malignant neoplasm | Altered Intercellular Communication | Dietary energy density, inflammation and energy balance in palliative care cancer patients. | 22727547 |
| Inflammation | Altered Intercellular Communication | Thus, targeting systemic inflammation may be important in nutritional interventions in this patient group. | 22727547 |
| Collagenous Sprue, Inflammatory disease of mucous membrane, Villous atrophy | Altered Intercellular Communication | Intestinal biopsies showed both villous atrophy and variable degrees of mucosal inflammation in 15 patients, and marked subepithelial collagen deposition (collagenous sprue) in 7. | 22728033 |
| Inflammation, Acute myocardial infarction, Atrial Fibrillation by ECG Finding | Altered Intercellular Communication | Activated inflammation is related to the incidence of atrial fibrillation in patients with acute myocardial infarction. | 22728476 |
| Atrial Fibrillation, Acute myocardial infarction, Inflammation, Atrial Fibrillation by ECG Finding | Altered Intercellular Communication | The purpose of this study was to investigate the relationship between the new onset of atrial fibrillation (AF) and inflammation in the early phase of acute myocardial infarction (AMI). | 22728476 |
| Inflammation, Atrial Fibrillation | Altered Intercellular Communication | Background Serial interaction between inflammation and the incidence of AF is not fully understood in the early phase of AMI. | 22728476 |
| Inflammation | Altered Intercellular Communication | MRI showed the inflammation in the sinus spread into the central nerve system. | 22729220 |
| Cholecystitis, Fibrosis Assessment, Inflammation, Inflammatory disorder | Altered Intercellular Communication | Xanthogranulomatous cholecystitis is an unusual inflammatory disease of the gallbladder characterised by severe proliferative fibrosis and the accumulation of lipid-laden macrophages in areas of destructive inflammation. | 22729338 |
| HD Term Type, Inflammation | Altered Intercellular Communication | Chronic inflammation is present in most HD patients. | 22729528 |
| Inflammation | Altered Intercellular Communication | Visual evoked potential (VEP) and multifocal electroretinogram (mfERG) in ocular syphilitic posterior segment inflammation. | 22729668 |
| Neurotransmitters, Movement Disorders, Neurologic Deficits, Impaired, Epilepsy | Altered Intercellular Communication | BH(4) deficiencies are a group of treatable pediatric neurotransmitter disorders that are characterized by motor dysfunction, mental retardation, impaired muscle tone, movement disorders and epileptic seizures. | 22729819 |
| Cholecystitis | Altered Intercellular Communication | In the present study we aimed to verify whether severe gallbladder inflammation would adversely affect the outcome of LCBDE. | 22729830 |
| Inflammation, Weight decreased, Malignant Head and Neck Neoplasm | Altered Intercellular Communication | Treatment of symptoms and systemic inflammation are important clinical targets to manage weight loss in patients with head and neck cancer, especially those treated with chemoirradiation. | 22730077 |
| Inflammation, Heart failure, Anemia | Altered Intercellular Communication | Inflammation and anaemia in a broad spectrum of patients with heart failure. | 22730482 |
| Inflammation, Anemia | Altered Intercellular Communication | Although inflammation is assumed to be an important cause of anaemia, the association between anaemia and inflammatory markers in patients with HF has not been well established. | 22730482 |
| Inflammation, Anemia | Altered Intercellular Communication | Anaemia is present in 40% of patients hospitalised for HF and is independently associated with inflammation. | 22730482 |
| Inflammation, Chronic Necrotizing Pulmonary Aspergillosis | Altered Intercellular Communication | Systemic biomarkers of inflammation and haemostasis in patients with chronic necrotizing pulmonary aspergillosis. | 22731696 |
| 2,3-Cyclic-Nucleotide Phosphodiesterases", Inflammation, Chronic Necrotizing Pulmonary Aspergillosis | Altered Intercellular Communication | The purpose of this study was to investigate mediators of inflammation and haemostasis in patients with chronic necrotizing pulmonary aspergillosis (CNPA), a locally, destructive process of the lung due to invasion by Aspergillus species. | 22731696 |
| 2,3-Cyclic-Nucleotide Phosphodiesterases", Inflammation, Thrombosis | Altered Intercellular Communication | Increased concentrations of circulating mediators of inflammation interleukin (IL)-6, IL-8, RANTES, TNF-a, ICAM-1 and mediators involved in endothelial activation and thrombosis (vWF, TF and PAI-1) were observed in patients with CNPA. | 22731696 |
| Inflammation, Metabolic Syndrome X | Altered Intercellular Communication | High-normal levels of liver enzymes, especially GGT, and systemic low-grade inflammation could be considered features of metabolic syndrome among children. | 22731985 |
| methyldopa, Inflammation | Altered Intercellular Communication | Oxidative damage and inflammation are related to the pathogenesis of age-related macular degeneration (AMD). | 22732187 |
| Primary malignant neoplasm | Altered Intercellular Communication | Prognostication in advanced cancer: a study examining an inflammation-based score. | 22732417 |
| Inflammation, Primary malignant neoplasm | Altered Intercellular Communication | Biomarkers of systemic inflammation (C-reactive protein and albumin) combined in the modified Glasgow Prognostic Score (mGPS) have been used to assist prognostication in various cancer types. | 22732417 |
| Inflammation, Liver carcinoma | Altered Intercellular Communication | A novel and validated prognostic index in hepatocellular carcinoma: the inflammation based index (IBI). | 22732513 |
| Inflammation, FAM126A gene | Altered Intercellular Communication | As chronic inflammation is associated with the pathogenesis of HCC, we explored the prognostic impact of a panel of inflammatory based scores, including the modified Glasgow Prognostic Score (mGPS), neutrophil to lymphocyte ratio (NLR) and platelet to lymphocyte ratio (PLR), in independent cohorts. | 22732513 |
| Inflammation, FAM126A gene | Altered Intercellular Communication | Systemic inflammation as measured by the mGPS, independently predicts overall survival in HCC. | 22732513 |
| Inflammation, FAM126A gene | Altered Intercellular Communication | These data enable formulation of a new prognostic system, the inflammation based index in HCC (IBI). | 22732513 |
| Inflammation, Diabetes Mellitus, Non-Insulin-Dependent, Obesity, Cardiovascular Diseases | Altered Intercellular Communication | Obesity is associated with lowgrade systemic inflammation which has been linked to the increased risk of cardiovascular disease and Type 2 diabetes in obese patients. | 22733212 |
| Refractory anemias, Inflammation, Rheumatoid Arthritis, Destruction (action) | Altered Intercellular Communication | Recent studies point to important roles for IL-17 and Th17 cells in sustaining chronic inflammation and articular destruction in rheumatoid arthritis (RA). | 22733231 |
| Inflammation, Primary malignant neoplasm, Fatigue | Altered Intercellular Communication | Inflammation and fatigue dimensions in advanced cancer patients and cancer survivors: an explorative study. | 22736424 |
| Inflammation, Fatigue | Altered Intercellular Communication | Inflammation may underlie cancer-related fatigue; however, there are no studies that assess the relation between fatigue and cytokines in patients with advanced disease versus patients without disease activity. | 22736424 |
| Inflammation, Primary malignant neoplasm, Fatigue | Altered Intercellular Communication | In advanced cancer, inflammation seems to be associated with physical fatigue, but not to mental fatigue. | 22736424 |
| Inflammation, Primary malignant neoplasm, Fatigue | Altered Intercellular Communication | In cancer survivors, there was no convincing evidence that inflammation plays a major role in fatigue. | 22736424 |
| Acute viral encephalitis, Inflammation | Altered Intercellular Communication | The patient was treated for acute viral encephalitis because of the presence of inflammation. | 22736758 |
| Inflammation, Dyslipidemias, Hypertension, CTCAE, Diabetes Mellitus | Altered Intercellular Communication | Rates of diabetes, dyslipidaemia, hypertension and inflammation are high and increased with age and were associated with urbanization. | 22738663 |
| Inflammation | Altered Intercellular Communication | PAI-1 synthesis in adipose tissue due to acute systemic inflammation may be a link between inflammation and impaired endogenous fibrinolysis. | 22740034 |
| Vitreous inflammatory cells | Altered Intercellular Communication | Marked resolution of the vitreous inflammation was observed in both eyes, and the serum b-D-glucan level was reduced. | 22740188 |
| Inflammation | Altered Intercellular Communication | Interestingly, white matter microglia from donors with peripheral inflammation displayed elevated CD45 levels and increased size and granularity, but were still distinct from macrophages. | 22740309 |
| Inflammation, Juvenile rheumatoid arthritis | Altered Intercellular Communication | Do patients with juvenile idiopathic arthritis in clinical remission have evidence of persistent inflammation on 3T magnetic resonance imaging? | 22740386 |
| Synovitis, Inflammation, Tenosynovitis | Altered Intercellular Communication | Over one-half of the patients in clinical remission had MRI evidence of persistent inflammation, defined as the presence of synovitis, tenosynovitis, or BMLs. | 22740386 |
| Traumatic injury | Altered Intercellular Communication | Bruises/contusions, strains, inflammation/swelling, and sprains were the most common types of injuries that occurred during both competition and training. | 22743236 |
| Inflammation, DLST wt Allele, Fatigue | Altered Intercellular Communication | DLTs were observed (fatigue, n = 2 and paronychial inflammation, n = 1) in three of 13 patients evaluated for DLTs. | 22743295 |
| Inflammation, Atherosclerosis | Altered Intercellular Communication | Inflammation is suggested to influence atherosclerosis, but could also increase PP. | 22743685 |
| Arterial Stiffness, Inflammation | Altered Intercellular Communication | This suggests that both estimated arterial stiffness and inflammation contribute through different pathways to risk of CVD. | 22743685 |
| Granuloma, Inflammation | Altered Intercellular Communication | Complications of tumorigenesis by a lacrimal silicone plug are rarely reported and most of them were cases of granuloma due to chronic inflammation. | 22743697 |
| Inflammation, Myasthenia Gravis, Thyroid associated opthalmopathies | Altered Intercellular Communication | Other causes were inflammation (n = 7, 16 %), myasthenia gravis (n = 5, 11 %), and thyroid ophthalmopathy (n = 1, 2 %). | 22743791 |
| Sepsis, Inflammation | Altered Intercellular Communication | Alterations of adiponectin in the course of inflammation and severe sepsis. | 22744305 |
| Inflammation, Ischemic stroke | Altered Intercellular Communication | Evidence is emerging that inflammation plays a key role in the pathophysiology of ischemic stroke (IS). | 22744645 |
| Inflammation, Cerebrovascular accident | Altered Intercellular Communication | We investigated the relationship between circulating markers of inflammation with brain and body temperature after stroke. | 22744672 |
| Inflammation, Cerebrovascular accident | Altered Intercellular Communication | Systemic inflammation after stroke is associated with elevated temperature in normal brain and the body but not with later ischemic brain temperature. | 22744672 |
| Airway structure, Colonization, Bronchiectasis, Damage | Altered Intercellular Communication | The vicious cycle hypothesis of bronchiectasis argues that bacterial colonization leads to airway inflammation and progressive lung damage. | 22744718 |
| Inflammation | Altered Intercellular Communication | Short- and long-term antibiotic treatments were associated with reductions in bacterial load, airways, and systemic inflammation. | 22744718 |
| Inflammation, Bronchiectasis, Exacerbation | Altered Intercellular Communication | High airway bacterial loads in non-CF bronchiectasis are associated with airway and systemic inflammation and a greater risk of exacerbations. | 22744718 |
| Inflammation, Tissue injury | Altered Intercellular Communication | Forkhead box P3 regulatory T cells control inflammatory responses, but it remains unclear whether they inhibit brain death-initiated inflammation and tissue injury in deceased kidney donors. | 22745276 |
| Inflammation | Altered Intercellular Communication | This suggests that NK cells respond to factors different from those driving T cell activation, but which are associated with inflammation in HIV patients. | 22745371 |
| Virus Diseases, Exacerbation | Altered Intercellular Communication | Thus our study demonstrates that in patients with COPD exacerbations, viral infection is directly associated with higher systemic levels of cytokines central to the development of the antiviral response, which are also known to contribute to inflammation-mediated tissue damage. | 22746693 |
| Percutaneous transhepatic cholangiography, Interstitial inflammation, Glomerulitis Assessment, Interstitial Fibrosis Assessment, Peritubular Capillaritis Assessment, Tubular atrophy | Altered Intercellular Communication | Peritubular capillaritis was present in 49 (84%), transplant glomerulitis was seen in 47 BS (81%), interstitial fibrosis and tubular atrophy in 47 (81%) and the thickening of the peritubular capillary (PTC) basement membrane (PTCBM) in 44 (76%), and interstitial inflammation was present in 26 BS (45%). | 22747474 |
| Inflammation | Altered Intercellular Communication | These results suggest that LRP-1 undergoes complex functional regulation following systemic inflammation which may depend on cell type, subcellular location, and post-translational modifications. | 22747709 |
| Inflammation, Data types - Address | Altered Intercellular Communication | Our findings that systemic inflammation causes deficits in both Ab transport and bulk flow like those observed in AD indicate that inflammation could induce and promote the disease. | 22747709 |
| Inflammation, Neurogenic Inflammation | Altered Intercellular Communication | However, there is no experimental evidence for a causal link between systemic inflammation or neuroinflammation and the onset of the disease. | 22747753 |
| Mesenteric Panniculitis, Fibrosis Assessment, Inflammation, Necrosis | Altered Intercellular Communication | Mesenteric panniculitis is a non-specific inflammation of the mesenteric adipose tissue, with varying degrees of fibrosis and fat necrosis. | 22748362 |
| Crohn Disease, Ulcerative Colitis | Altered Intercellular Communication | Several studies identified the presence of Epstein-Barr virus-infected B cells in the lesions of Crohn disease and ulcerative colitis suggesting that colon mucosa with chronic inflammation could be a potential site of Epstein-Barr virus replication. | 22748471 |
| Inflammation, Appendicitis, CTCAE, chronic diverticulitis | Altered Intercellular Communication | This density was similar to that observed in chronic diverticulitis but higher when compared with appendicitis, suggesting that chronic rather than acute inflammation facilitates the recruitment of Epstein-Barr virus-infected cells in diseased tissues. | 22748471 |
| Diabetes with coma (disorder), Inflammation | Altered Intercellular Communication | Expression of angiotensin-converting enzyme 2 and its end product angiotensin 1-7 is increased in diabetic atheroma: implications for inflammation and neovascularization. | 22749485 |
| Refractory anemias, Inflammation | Altered Intercellular Communication | PET/CT detection of inflammation in the ischial tuberosities, greater trochanters, and spinous processes discriminated between PMR and RA, but not between SpA and PMR. | 22749663 |
| Inflammation, Paresthesia, Nerve injury, Peri-Implantitis | Altered Intercellular Communication | For patients who experience transient paresthesia and recovery owing to nerve damage caused by the placement of an implant in the mandibular molar or premolar area, or in patients in whom the implant is close to the inferior alveolar nerve canal or the mental nerve, the spread of inflammation caused by peri-implantitis can induce paresthesia. | 22749709 |
| Intestinal metaplasia, Inflammation | Altered Intercellular Communication | Methylation-dependent activation of CDX1 through NF-kB: a link from inflammation to intestinal metaplasia in the human stomach. | 22749770 |
| Inflammation, Observation Method - Coagulation | Altered Intercellular Communication | Thrombin-activatable fibrinolysis inhibitor (TAFI), a procarboxypeptidase in plasma, plays a dual role in regulating both coagulation and inflammation. | 22749979 |
| Traumatic injury | Altered Intercellular Communication | This pilot study shows that TAFI levels are inversely correlated with inflammation-associated development of complications after major trauma. | 22749979 |
| palladium, Inflammation | Altered Intercellular Communication | Inflammation has been implicated in PD, and alpha-synuclein can initiate microglial activation; however, the kinetics and distribution of inflammatory responses to alpha-synuclein overexpression in vivo are not well understood. | 22750327 |
| Inflammation, Sarcopenia | Altered Intercellular Communication | Sarcopenia was positively associated with mobility impairment and inflammation and negatively with BMI. | 22750356 |
| Refractory anemias, Inflammation | Altered Intercellular Communication | The volume of inflammation was significantly higher in RA than in PsA for all the extensor compartments except the second, and in the joint synovial membrane. | 22751591 |
| PROS1 gene, Inflammation | Altered Intercellular Communication | The DCE-MRI indicators of the degree of inflammation were higher for PsA in the joint synovial membrane (p = 0.002 and p < 0.001, respectively). | 22751591 |
| Inflammation | Altered Intercellular Communication | There was a significant correlation between volume of inflammation but not its degree and 28-joint Disease Activity Score at the level of the wrist joint (r = 0.6; p = 0.01). | 22751591 |
| Inflammation, Sheehan Syndrome, pituitary dysfunction | Altered Intercellular Communication | High CD3 (+) DR (+) expression that correlates with the duration of illness in Sheehan's patients is suggestive of an ongoing inflammation accompanying the slow progression of pituitary dysfunction in Sheehan's syndrome. | 22752347 |
| Orbital Pseudotumor, Thyroid associated opthalmopathies | Altered Intercellular Communication | Our results suggest that the increased concentrations of CXCL9 (and CXCL10), at least in part, reflect the activity of orbital inflammation and therefore these chemokines could serve as a guideline in therapeutic decision-making in patients with Graves' orbitopathy. | 22752955 |
| Inflammation, Non-alcoholic Fatty Liver Disease, Fatty degeneration, Fatty Liver Disease | Altered Intercellular Communication | In NASH patients, VDR expression on cholangiocytes was inversely correlated with steatosis severity (P < 0.02), lobular inflammation (P < 0.01), and nonalcoholic fatty liver disease score (P < 0.03). | 22753133 |
| Carcinogenic Chlorinated Hydrocarbon, Fibrosis Assessment, Inflammation | Altered Intercellular Communication | In CHC subjects, fibrosis stage was associated with low hepatic CYP27A1 expression, whereas portal inflammation was significantly higher in patients with VDR-negative inflammatory cells (P < 0.009) and low VDR expression in hepatocytes (P < 0.03). | 22753133 |
| vascular inflammations | Altered Intercellular Communication | Epigallocatechin gallate reduces vascular inflammation in db/db mice possibly through an NF-kB-mediated mechanism. | 22753231 |
| vascular inflammations, Atherosclerosis, Diabetes Mellitus | Altered Intercellular Communication | Hyperglycemia-induced vascular inflammation resulting in the adhesion of monocytes to endothelium is a key event in the pathogenesis of atherosclerosis in diabetes. | 22753231 |
| vascular inflammations, Diabetes Mellitus | Altered Intercellular Communication | We investigated whether epigallocatechin gallate (EGCG), a major catechin found in green tea, reduces vascular inflammation in diabetes. | 22753231 |
| vascular inflammations, Diabetes Mellitus | Altered Intercellular Communication | EGCG may have a direct protective effect against vascular inflammation in diabetes. | 22753231 |
| Central hypothyroidism, Hypogonadism, Hyperprolactinemia | Altered Intercellular Communication | The most common hormonal features were gonadotropin deficiency (n=21), TSH deficiency (n=15) and hyperprolactinemia (n=12). | 22753675 |
| Inflammation, Hyperparathyroidism, Primary, Cyclophosphamide/Vincristine/Dacarbazine Regimen, Cardiovascular Diseases | Altered Intercellular Communication | Primary hyperparathyroidism (PHPT) has been associated with low-grade inflammation and elevated risk of cardiovascular disease (CVD). | 22757621 |
| Arthritis, Headache | Altered Intercellular Communication | Arthritis, other inflammation-related musculoskeletal conditions, and headaches were associated with increased BPH risk (hazard ratio (HR) = 1.77 (95% confidence interval (CI): 1.37, 2.29), HR = 1.57 (95% CI: 1.14, 2.17), and HR = 1.40 (95% CI: 1.09, 1.80), respectively). | 22759721 |
| Hepatitis | Altered Intercellular Communication | We also found a positive correlation between the level of ferritin and liver inflammation during treatment (p<0.01). | 22760008 |
| Autoimmune Diseases, Inflammation | Altered Intercellular Communication | Although Th22 and Th17 cells have been reported to play critical roles during autoimmunity and inflammation, information on their role in cancer-immunity is limited. | 22760549 |
| Inflammation, Fibrosis Assessment, Edema, Lacrimal Duct Obstruction | Altered Intercellular Communication | Radioactive iodine uptake by nasolacrimal duct mucosa with subsequent inflammation, edema and fibrosis seems to have a relationship to lacrimal duct obstruction. | 22760799 |
| Vitritis, Vitreous opacities, Acute inflammation, Uveitis | Altered Intercellular Communication | 25-gauge vitrectomy has proven its efficacy on cleansing vitreous opacities and improving visual acuity on patients with residual vitritis secondary to uveitis with minimal postoperative inflammation and complications. | 22760801 |
| Inflammation, Adenoma, Adenomatous Polyps | Altered Intercellular Communication | An initial exploration of a possible association of 5q loss with inflammation indicated that tumor-infiltrating lymphocytes were more abundant in the stroma of flat adenomas compared with that of polypoid adenomas. | 22761468 |
| Inflammation, Adenoma | Altered Intercellular Communication | Alterations more specific to flat adenomas, in particular 5q loss, may be associated with inflammation. | 22761468 |
| Inflammation | Altered Intercellular Communication | Eradicating HP reduces gastric inflammation, but does not eliminate it. | 22761739 |
| Inflammation, Stomach Carcinoma | Altered Intercellular Communication | We speculate that this persistent inflammation might contribute to gastric mucosal pathology, for example, persistent increased gastric cancer risk despite eradication of HP. | 22761739 |
| Inflammation, Sepsis, Autoimmune Diseases, Communicable Diseases, Acute Coronary Syndrome, Rheumatoid Arthritis, GDC AJCC Clinical Stage Terminology | Altered Intercellular Communication | The myeloperoxidase (MPO) content of circulating neutrophils was determined by flow cytometry in 330 subjects: 69 consecutive patients with acute coronary syndromes (ACS), 69 with chronic stable angina (CSA), 50 with inflammation due to either non-infectious (acute bone fracture), infectious (sepsis) or autoimmune diseases (small and large vessel systemic vasculitis, rheumatoid arthritis). | 22761804 |
| granulomatous uveitis, Inflammatory abnormality of the eye, Uveitis | Altered Intercellular Communication | Ocular inflammation was bilateral in 16 patients (69,6%), typical aspects of granulomatous uveitis were found in only 16 eyes over 39 (41%), posterior uveitis was found in 18 eyes (46.2%), with an averaged visual acuity of 5/10. | 22763184 |
| Inflammatory abnormality of the eye | Altered Intercellular Communication | The visual prognosis was good, with visual acuity greater than 6/10 in 96% of the cases if the ocular inflammation spared retina and choroid. | 22763184 |
| Intraocular inflammation, Sarcoidosis | Altered Intercellular Communication | Sarcoidosis may be revealed by an intraocular inflammation, with typical patterns in only 43% of the cases. | 22763184 |
| Inflammation, Overweight, physiopathological, Cardiovascular Diseases | Altered Intercellular Communication | Air pollution and autonomic and vascular dysfunction in patients with cardiovascular disease: interactions of systemic inflammation, overweight, and gender. | 22763390 |
| Inflammation, Overweight, physiopathological, Cardiovascular Diseases | Altered Intercellular Communication | The authors conclude that autonomic and vascular dysfunction may be one of the mechanisms through which air pollution exposure can increase cardiovascular disease risk, especially among persons with systemic inflammation and overweight. | 22763390 |
| Inflammation, Hypertension, CTCAE | Altered Intercellular Communication | C-reactive protein (CRP), an acute phase reactant and marker of inflammation, has been shown to be associated with CRP genetic variants and incident hypertension, but it is unclear whether this link is causal. | 22763479 |
| Inflammation | Altered Intercellular Communication | Chronic, low-grade inflammation involves general production of pro-inflammatory cytokines and inflammatory markers and is a typical feature of aging. | 22763966 |
| Sarcoidosis, Non-necrotizing granulomatous inflammation | Altered Intercellular Communication | Patient underwent posterior fossa craniotomy with biopsy of left cerebellar lesion which revealed non-caseating chronic granulomatous inflammation, consistent with sarcoidosis. | 22764471 |
| hearing impairment, Inflammation, Perforation (observation), Otitis Media with Effusion | Altered Intercellular Communication | Secretory otitis media (SOM) is a chronic, nonpurulent inflammation of the middle ear, characterized by a long-term presence of liquids of different density in the middle ear for at least three consecutive months, different degrees of hearing loss and the absence of perforation of the eardrum. | 22764543 |
| Granuloma, Inflammation | Altered Intercellular Communication | A biopsy showed well formed granulomas, mixed inflammation with a predominance of neutrophils, and acid-fast bacilli. | 22764735 |
| Inflammation, Tumor necrosis | Altered Intercellular Communication | Inflammation, and especially tumour necrosis factor alpha (TNFa), has been associated with IR, and the administration of anti-TNFa agents is suggested to improve insulin sensitivity. | 22765047 |
| Endometriosis | Altered Intercellular Communication | Cutaneous deciduosis represents a rare manifestation of cutaneous endometriosis in which typical endometrial glands and stroma are morphologically and physiologically transformed under hormonal influence. | 22765523 |
| Inflammation, Chronic Obstructive Airway Disease | Altered Intercellular Communication | [Characteristics of stable chronic obstructive pulmonary disease related to systemic inflammation]. | 22766062 |
| ARCN1 gene, Inflammation, Chronic Obstructive Airway Disease | Altered Intercellular Communication | Chronic obstructive pulmonary disease (COPD) is characterized by a systemic inflammation. | 22766062 |
| Myelofibrosis, Inflammation | Altered Intercellular Communication | In all specimens' area of bone, osteoid and remaining tissue were histomorphometrically determined and presence of cement particles, bone marrow fibrosis and signs of inflammation were recorded. | 22766263 |
| Inflammation, physiopathological, Thin-cap fibroatheroma | Altered Intercellular Communication | We hypothesized that microvascular dysfunction is associated with greater systemic inflammation and is a predictor of virtual histology-intravascular ultrasound (VH-IVUS)-defined coronary thin-cap fibroatheromas. | 22766333 |
| Inflammation, Brucellosis | Altered Intercellular Communication | Magnetic resonance imaging can detect thoracic inflammation due to familial Mediterranean fever. | 22766764 |
| Inflammation, Fibrosis Assessment | Altered Intercellular Communication | The IL28B genotype is predictive not only of SVR but also of the histologic diagnosis of posttransplant hepatitis C, with donor CC genotype favoring inflammation and fibrosis, and adverse outcomes during long-term follow-up. | 22766768 |
| Inflammation, Hepatitis, Necrosis | Altered Intercellular Communication | One key histological pattern in transplant liver pathology is spotty hepatocyte necrosis without significant lobular inflammation, which is typical of recurrent hepatitis C. Over the past years, we have observed several liver biopsies with a pattern of injury that mimicked the histological findings of early recurrent hepatitis C. This pattern consisted of increased lobular hepatocyte spotty necrosis without significant inflammation, but with the additional finding of numerous concurrent mitotic figures. | 22766789 |
| Inflammation | Altered Intercellular Communication | There was no significant difference between the study and the control groups in portal and lobular inflammation. | 22766789 |
| Inflammation, Liver Failure | Altered Intercellular Communication | In summary, our findings indicate that the histological pattern of concurrent increases in both hepatocyte mitosis and apoptosis in a post-transplant liver biopsy without significant lobular inflammation is strongly associated with hepatic arterial insufficiency and should prompt evaluation of the hepatic artery. | 22766789 |
| Inflammation, Sunburn | Altered Intercellular Communication | UV reactivation is an uncommon reaction characterized by recurrent inflammation in areas of prior sunburn or UV exposure following the administration of a triggering drug. | 22768437 |
| Communicable Diseases, Inflammation | Altered Intercellular Communication | Recently identified protein hepcidin synthesized in the liver, is thought to be a key regulator for iron homeostasis and is induced by infection and inflammation. | 22768976 |
| HD Term Type, Inflammation, Hepatitis C | Altered Intercellular Communication | We investigated the association of prohepcidin with inflammation and iron parameters in HD patients with and without chronic HCV infection. | 22768976 |
| Acute and chronic inflammation | Altered Intercellular Communication | The etiology is unclear, however it is considered to be secondary to chronic sinonasal inflammation. | 22770260 |
| Inflammation, MS gene | Altered Intercellular Communication | Correlations between serum uric acid level and disease activity, intrathecal inflammation reactivity in patients with multiple sclerosis. | 22770406 |
| Disability, Inflammation | Altered Intercellular Communication | In MS patients, UA levels might partly reflect the extent of disability and inflammation. | 22770406 |
| Inflammation | Altered Intercellular Communication | This may be related to differential contribution of neutrophil and lymphocyte to inflammation during AMI in diabetics vs. non-diabetics. | 22771557 |
| Renal Circulation, Inflammation, Injury of kidney | Altered Intercellular Communication | Renal vein blood from post-stenotic human kidneys has multiple markers reflecting active inflammation that portends kidney injury and reduced function. | 22771675 |
| Inflammation, Pain Distress Question, Fever, CTCAE, Brucellosis, Autosomal Recessive Disorder, Familial Mediterranean Fever | Altered Intercellular Communication | Familial Mediterranean fever (FMF) is an autosomal recessive disorder characterized by recurrent attacks of fever and inflammation in the peritoneum, synovium, or pleura, accompanied by pain. | 22771921 |
| Inflammation | Altered Intercellular Communication | DNA-damage response associated with occupational exposure, age and chronic inflammation in workers in the automotive industry. | 22772077 |
| Ultraviolet B radiation, Sunburn, Carcinogenesis, Inflammation | Altered Intercellular Communication | Exposure to ultraviolet B (UVB) radiation from the sun can result in sunburn, premature aging and carcinogenesis, but the mechanism responsible for acute inflammation of the skin is not well understood. | 22772463 |
| Inflammation, Atherosclerosis, Cerebrovascular accident | Altered Intercellular Communication | Due to the fact that majority of carotid atheromatous plaques appear to be unstable or potentially unstable because of the inflammation and related mechanisms, the role of the inflammatory-immunologic component of atherosclerosis should be used in prophylaxis of stroke and the new therapeutic concepts worked out. | 22773462 |
| Inflammation | Altered Intercellular Communication | Bronchoalveolar lavage fluid from 66 was analyzed for the level of cellular inflammation, cytokines, and soluble leptin. | 22773729 |
| Inflammatory abnormality of the eye | Altered Intercellular Communication | No serious adverse event or ocular inflammation was reported in either group. | 22775078 |
| Gingivitis, Calculi, Dental Plaque | Altered Intercellular Communication | To analyze the diagnostic reliability of various partial-mouth recording systems (PMRS) for the simultaneous assessment of supragingival plaque, calculus, and gingival inflammation in a population of Portuguese adults. | 22775296 |
| Gingivitis, Calculi, Dental Plaque | Altered Intercellular Communication | A single examiner determined the levels of plaque, calculus, and gingival inflammation in 108 subjects using quantitative and dichotomous indices. | 22775296 |
| Degenerative polyarthritis, Rheumatoid Arthritis, Inflammation, Pain Distress Question | Altered Intercellular Communication | Rheumatoid arthritis and osteoarthritis are two diseases associated with severe pain, inflammation and limited activity. | 22776021 |
| Inflammation, Postpoliomyelitis Syndrome | Altered Intercellular Communication | Expression of inflammatory cytokines in cerebrospinal fluid (CSF) has led to the hypothesis of intrathecal chronic inflammation to explain the denervation observed in post-polio syndrome (PPS). | 22776106 |
| Inflammation, Calculus of cystic duct, anatomic, iatrogenic injury, Umbilical hernia | Altered Intercellular Communication | One hundred and ten patients (84.6%) underwent successful single-fulcrum LC, and 20 patients (15.4%) were converted to conventional surgery (n= 18) or required additional trocars (n= 2) during the procedure because of umbilical hernia (n= 3), severe inflammation or adhesion (n= 9), impacted cystic duct stone (n= 3), anatomical anomaly (n= 3) and iatrogenic injury (n= 2). | 22776541 |
| Inflammation, Overweight | Altered Intercellular Communication | Increased inflammation is present in obese compared with normal weight individuals, but inflammation characteristics of nonobese, overweight individuals are less clear. | 22776879 |
| Multiple Organ Failure, Cessation of life, Organ dysfunction syndrome, Shock, Hemorrhagic | Altered Intercellular Communication | Posttraumatic inflammation and excessive neutrophil activation cause multiple organ dysfunction syndrome (MODS), a major cause of death among hemorrhagic shock patients. | 22777113 |
| Post-Traumatic Stress Disorder, Inflammation | Altered Intercellular Communication | Traditional resuscitation strategies may exacerbate inflammation; thus, novel fluid treatments are needed to reduce such posttraumatic complications. | 22777113 |
| Inflammation, Staphylococcus aureus infection, Atopy, Exacerbation of cGVHD, Eczema | Altered Intercellular Communication | S aureus infection leads to exacerbation of eczema and may induce flares in atopic skin by mediating inflammation. | 22777229 |
| Inflammation, Pelvic Organ Prolapse, Irritation, Gastrointestinal mucositis | Altered Intercellular Communication | It is possible that pelvic organ prolapse caused irritation and inflammation of vaginal epithelium and contributed to the development of plasma cell mucositis in these areas. | 22777378 |
| Crohn Disease, Gastrointestinal inflammation | Altered Intercellular Communication | Crohn disease (CD) is primarily considered an inflammatory condition of the small and large intestine although associated extraintestinal inflammation is relatively common. | 22777510 |
| Crohn Disease, Gastrointestinal inflammation | Altered Intercellular Communication | Crohn disease (CD) is primarily considered an inflammatory condition of the small and large intestine although associated extraintestinal inflammation is relatively common. | 22777510 |
| Inflammation, Rheumatoid Arthritis | Altered Intercellular Communication | Glycoprotein 96 perpetuates the persistent inflammation of rheumatoid arthritis. | 22777994 |
| Refractory anemias, Arthritis | Altered Intercellular Communication | Supporting the role of gp96 in RA, joint tissue gp96 expression was induced in mice with the K/BxN serum-induced arthritis, and neutralizing antibodies to gp96 ameliorated joint inflammation, as determined by clinical and histologic examination. | 22777994 |
| Communicable Diseases, Inflammation, Neoplasms | Altered Intercellular Communication | FDG is not tumor specific; it can accumulate in inflammation, infection, and post-therapy settings. | 22778055 |
| Inflammation, Hemorrhage, Gangrene, Fibrosis Assessment, Edema, Malignant Neoplasms | Altered Intercellular Communication | Her histology described 'haemorrhage within the gallbladder wall along with oedema, fibrosis and patchy inflammation and no signs of malignancy or gangrene'. | 22778467 |
| Inflammation, Goblet Cells, Squamous metaplasia | Altered Intercellular Communication | Histological findings of inflammation for all specimen and mucous cell prosoplasia, squamous metaplasia, glandular epithelium for all DFs were stained with hematoxyline and eosin, periodic acid schiff, alcian blue, and mucin. | 22778705 |
| Inflammation, Goblet Cells, Squamous metaplasia | Altered Intercellular Communication | The histologic examinations showed 16% mucous cell prosoplasia, 54% squamous metaplasia, 20% glandular epithelium, 37% inflammation. | 22778705 |
| Inflammation | Altered Intercellular Communication | Inflammation was detected in all RCs and %62 in DF, %43 in DC and KCOT. | 22778705 |
| Inflammation | Altered Intercellular Communication | The results of this study indicated that the higher MCM-2 expressions in RC than the KCOT might be related to the inflammation and this protein might be more sensitive to inflammation. | 22778705 |
| Inflammation, Interstitial inflammation, Neoplasms, Pneumonitis, CTCAE, Fibrosis Assessment | Altered Intercellular Communication | The cases were categorised on the basis of histopathology into six patterns: (1) adequate biopsy without a specific diagnostic abnormality (n = 137, 22.3%); (2) acute pneumonitis (n = 29, 4.7%); (3) neoplasia (n = 109, 17.7%); (4) chronic interstitial inflammation with or without fibrosis (n = 138, 22.4%); (5) granulomatous inflammation, (n = 186, 30.2%); and (6) other specific causes (n = 16, 2.6%). | 22779117 |
| Inflammation, Periodontitis | Altered Intercellular Communication | Sites of inflammation were identified on subjects with moderate-to-severe chronic periodontitis, and were allocated to either patch placement or untreated controls, both for 24 hours. | 22779219 |
| Gingivitis | Altered Intercellular Communication | This pilot study indicates that a topical gingival patch promotes reduction of gingival inflammation. | 22779219 |
| Inflammation, Dental caries | Altered Intercellular Communication | The results demonstrated a relatively high caries experience, low level of gingival inflammation and relation between GI and DMFT, particularly in D component, and between GI and orthodontic anomalies. | 22779381 |
| Inflammation, Periodontal Diseases, Obesity | Altered Intercellular Communication | Alpha-defensins may play a role in gingival inflammation, and be involved in the higher susceptibility of obese patients to periodontal diseases. | 22780105 |
| Periodontal Infection | Altered Intercellular Communication | To investigate whether low-grade inflammation-related factors such as serum low-density (LDL-C) and high-density lipoprotein cholesterol (HDL-C) modify the association between periodontal infection and C-reactive protein. | 22780440 |
| Periodontal Infection | Altered Intercellular Communication | This study suggests that the relation of periodontal infection to the systemic inflammatory condition is more complicated than previously presumed. | 22780440 |
| Inflammation | Altered Intercellular Communication | Base excision repair gene polymorphisms are associated with inflammation in patients undergoing chronic hemodialysis. | 22780951 |
| Inflammation | Altered Intercellular Communication | Chronic inflammation may increase the risk of mortality for patients undergoing hemodialysis, while enhanced oxidative stress and DNA oxidative damage are involved in the inflammatory response. | 22780951 |
| Malignant neoplasm of esophagus, Inflammation, Hindi language, Intraepithelial Neoplasia | Altered Intercellular Communication | Among them, 88 were pathology-proven inflammation, 5 were pathology-proven esophageal cancers, 20 were pathology-proven low intraepithelial neoplasia (LIN) and 33 were pathology-proven high intraepithelial neoplasia (HIN) detected with NBI-ME. | 22781948 |
| Inflammation, Primary malignant neoplasm | Altered Intercellular Communication | By a per-lesion analysis, the accuracy of inflammation and cancer were 100% (88/88) and 7/7. | 22781948 |
| Primary malignant neoplasm, Esophagitis | Altered Intercellular Communication | Higher diagnostic accuracy of IPCL indicates the feasibility of NBI-ME for the efficacious diagnosis of esophageal inflammation and cancer. | 22781948 |
| Asthma | Altered Intercellular Communication | Chronic endobronchial inflammation is a hallmark of pediatric asthma and involves the arachidonic acid pathway. | 22782807 |
| Inflammation, Prostate carcinoma, Structure of posterior cerebral artery | Altered Intercellular Communication | Inflammation has been implicated in prostate cancer (PCa) pathogenesis. | 22782910 |
| Autoimmune Diseases, Endocrine System Diseases | Altered Intercellular Communication | Tests for autoantibodies indicating autoimmune disease were also negative, and hormonal assays for the detection of endocrine disease were normal. | 22782959 |
| Inflammation | Altered Intercellular Communication | Ultrasound showed no evidence of inflammation of pancreas. | 22783000 |
| Inflammation | Altered Intercellular Communication | 11beta-HSD1 expression within bone also increases with age and inflammation. | 22783780 |
| Osteoporosis | Altered Intercellular Communication | This implicates locally produced glucocorticoids in age-related and inflammation-associated osteoporosis. | 22783780 |
| Inflammation | Altered Intercellular Communication | Activity increases with joint inflammation and could represent a local anti-inflammatory system. | 22783780 |
| Inflammation, Cardiovascular Diseases | Altered Intercellular Communication | Chronic inflammation that occurs with aging is one of the risk factors for cardiovascular disease. | 22784030 |
| Cardiovascular morbidity, Inflammation | Altered Intercellular Communication | Regular exercise may prevent cardiovascular morbidity by decreasing chronic systematic inflammation. | 22784030 |
| Communicable Diseases, Inflammation, Stenosis | Altered Intercellular Communication | In adults, secondary proximal irreversible fibrotic strictures or bony changes around the nasolacrimal duct typically arise from chronic inflammation or low grade infection. | 22784678 |
| Neoplasms, Aspects of congenital malformations, Swelling, Diverticulum, Dermoid Cyst | Altered Intercellular Communication | The differential diagnosis of medial canthal swellings centered on the lacrimal sac spans malformations, diverticula, dermoid/epidermoid cysts, sac inflammations/infections causing swelling without generalized sac enlargement, encephaloceles and primary epithelial tumors, as well as extrinsic tumors impinging on the sac. | 22784678 |
| Sarcoidosis, Granulomatous, Non-necrotizing granulomatous inflammation | Altered Intercellular Communication | Sarcoidosis is a non-caseating, granulomatous, epithelioid inflammation. | 22784795 |
| Muscle damage, Inflammation | Altered Intercellular Communication | Mini-midvastus versus medial parapatellar approach in TKA: muscle damage and inflammation markers. | 22784897 |
| Airway structure | Altered Intercellular Communication | Further, treatment children had a greater decrease in exhaled nitric oxide (-9.62 vs -0.39, P = .03), suggesting reduction in airway inflammation. | 22785264 |
| Inflammation | Altered Intercellular Communication | Low-grade inflammation offers a possible biological pathway, which has been confirmed in men but not in women. | 22786845 |
| Inflammation, Postoperative Complications, Extravasation of lymph, Lymphedema | Altered Intercellular Communication | Various postoperative complications (inflammation and wound dehiscence, lymphorrhoea, lymphocyst and limb lymphedema) developed in 9 (21.9%) and the local regional recurrence was recorded in 7 (17%) patients. | 22788055 |
| Inflammation, Hypereosinophilia, Unspecified visual loss | Altered Intercellular Communication | The present case strongly suggests that the occurrence of visual loss in the context of systemic inflammation with hypereosinophilia should lead to considering the diagnosis of CSS. | 22789694 |
| hearing impairment, Inflammation, Cochlear Nerve | Altered Intercellular Communication | We presume that the hearing impairment was due to auditory nerve neuritis related to extension of inflammation of the meninges. | 22790140 |
| allergic inflammation | Altered Intercellular Communication | These chemoattractants are selective for leukocyte subsets involved in acute inflammatory responses and allergic inflammation. | 22790593 |
| Sepsis, Inflammation, Organ Dysfunction Scores | Altered Intercellular Communication | REsearching severe Sepsis and Organ dysfunction in children: A gLobal perspective (RESOLVE), a phase III trial of drotrecogin alfa (activated) in pediatric severe sepsis, examined biomarker changes in inflammation and coagulation. | 22791090 |
| Inflammation, Observation Method - Coagulation, Congenital Abnormality | Altered Intercellular Communication | While children in the RESOLVE trial were similar to adults in that they showed a relationship between severity of coagulation and inflammation abnormalities and mortality, their pharmacodynamic response to drotrecogin alfa (activated) differed with respect to changes in protein C activity and systemic inflammation. | 22791090 |
| Airway structure | Altered Intercellular Communication | The data should be considered in the interpretation of FeNO levels in clinical practice and setting up FeNO screening criteria for identification of eosinophilic airway inflammation. | 22791639 |
| Myocarditis, Cardiomyopathies | Altered Intercellular Communication | Slowly resolving global myocardial inflammation/oedema in Tako-Tsubo cardiomyopathy: evidence from T2-weighted cardiac MRI. | 22791656 |
| Pain Distress Question, Arthritis, Inflammation, Federated States of Micronesia | Altered Intercellular Communication | The authors examined the incidence of secondary FM in an early inflammatory arthritis cohort, and assessed the association between pain, inflammation, psychosocial variables and the clinical diagnosis of FM. | 22791744 |
| Inflammation, Federated States of Micronesia, Pain Distress Question | Altered Intercellular Communication | Although inflammation was not associated with the clinical diagnosis of FM, pain severity and poor mental health were associated with the clinical diagnosis of FM. | 22791744 |
| ARCN1 gene, Inflammation, Chronic Obstructive Airway Disease, Pulmonary Emphysema | Altered Intercellular Communication | Chronic obstructive pulmonary disease (COPD) related to wood smoke exposure is characterized by important inflammation of the central and peripheral airways without significant emphysema. | 22791990 |
| Lung Injury, Diaphragmatic Hernia, Chronic lung disease | Altered Intercellular Communication | The development of chronic lung disease was caused by lung injury under high oxidative and inflammatory conditions in the setting of a diaphragmatic hernia. | 22791992 |
| palladium | Altered Intercellular Communication | PD has a complex profile of neurochemical deficits in which abnormalities of different neurotransmitter systems may play significant and differing roles in the development of non-motor features. | 22792235 |
| Inflammation, Organ Dysfunction Scores, Atherosclerosis | Altered Intercellular Communication | In summary, the altered plasma proteins in LHD implicated accelerated atherosclerosis, defective antioxidative activity, increased inflammation/infection, and organ dysfunction. | 22792249 |
| Perifolliculitis | Altered Intercellular Communication | In 1-9 year-olds, the prevalence of trachomatous inflammation-follicular (TF) was 17.5% (95% CI: 15.7-19.5%). | 22792311 |
| glycation, Inflammation, Endothelial dysfunction, Diabetic Angiopathies | Altered Intercellular Communication | Formation of advanced glycation endproducts (AGEs), endothelial dysfunction, and low-grade inflammation are intermediate pathways of hyperglycemia-induced vascular complications. | 22792314 |
| Inflammation, Endothelial dysfunction | Altered Intercellular Communication | Compared to placebo, benfotiamine did not result in significant reductions in plasma or urinary AGEs or plasma markers of endothelial dysfunction and low-grade inflammation. | 22792314 |
| Inflammation, Airway Obstruction | Altered Intercellular Communication | However, it is unclear, based on our current understanding of macrophage functional heterogeneity, if immature AM improve viral clearance or contribute to inflammation and airway obstruction in the IFNg-deficient neonatal lung environment. | 22792355 |
| Inflammation, Myocardial Ischemia, Atherosclerosis | Altered Intercellular Communication | We compared new non-lipid atherosclerosis indexes related to inflammation and macrophage stimulation (serum concentration of cystatin C, matrix metalloproteases and chitotriosidase activity) with common inflammatory (high sensitivity C reactive protein) and lipid markers in elderly persons and patients with atherosclerosis and ischemic heart disease who have undergone coronary bypass surgery. | 22792735 |
| Airway structure, Chronic Obstructive Airway Disease | Altered Intercellular Communication | It has been shown that changes of nitrite could be observed in acute inflammation of upper airways and in a person with diagnosed mild chronic obstructive pulmonary disease, while changes of other ions could also be observed. | 22796027 |
| Inflammation, Metabolic Syndrome X, Schizophrenia | Altered Intercellular Communication | Relationship between inflammation and metabolic syndrome following treatment with paliperidone for schizophrenia. | 22796278 |
| Inflammation, Metabolic Syndrome X | Altered Intercellular Communication | Metabolic syndrome and antipsychotic medications are associated with inflammation. | 22796278 |
| Inflammation, Metabolic Syndrome X, Schizophrenia | Altered Intercellular Communication | This study investigated the relationship between inflammation and metabolic syndrome in patients with schizophrenia. | 22796278 |
| Schizophrenia, Inflammation, Metabolic Syndrome X | Altered Intercellular Communication | Schizophrenic patients with high levels of inflammation should be carefully monitored for metabolic syndrome. | 22796278 |
| Inflammation, Schizophrenia, Metabolic Syndrome X, Obesity | Altered Intercellular Communication | Moreover, strategies to reduce inflammation and obesity may prevent metabolic syndrome in patients with schizophrenia who take atypical antipsychotic medication. | 22796278 |
| Inflammatory abnormality of the eye, Uveitis | Altered Intercellular Communication | Patients with noninfectious uveitis seen between 1979 and 2007 at 4 academic ocular inflammation specialty clinics. | 22796306 |
| Ocular Hypotension, Uveitis | Altered Intercellular Communication | The risk of hypotony is low among eyes with noninfectious uveitis, but is more frequently observed in cases with anterior segment inflammation. | 22796306 |
| Inflammation | Altered Intercellular Communication | Signs of present or past inflammation were associated with greater risk, suggesting excellent inflammatory control may reduce the risk of hypotony. | 22796306 |
| Hyperlipidemia, Hypertension, CTCAE, Inflammation, Atherosclerosis | Altered Intercellular Communication | There are many factors contributing to the progression of atherosclerosis, including hypertension, hyperlipidemia, the renin-angiotensin system, and inflammation. | 22796540 |
| Inflammation | Altered Intercellular Communication | In these patients, the chronic low-grade inflammation may predispose to vascular remodelling and arterial stiffening. | 22796713 |
| Inflammation | Altered Intercellular Communication | Upregulation of D6 in AMs could indicate that, besides its known scavenger activity in acute inflammation, D6 may have additional roles in chronic inflammatory conditions possibly promoting immune activation. | 22797410 |
| ARCN1 gene | Altered Intercellular Communication | We, therefore, investigated the involvement of D6 in the immune responses in COPD, a chronic inflammatory condition of the lung. | 22797410 |
| Inflammation | Altered Intercellular Communication | Upregulation of D6 in AMs could indicate that, besides its known scavenger activity in acute inflammation, D6 may have additional roles in chronic inflammatory conditions possibly promoting immune activation. | 22797410 |
| Inflammation, Acute infectious disease | Altered Intercellular Communication | On examination there was dried blood overlying the right ear drum and very mild inflammation of the canal but no obvious acute infection. | 22797479 |
| Behcet Syndrome | Altered Intercellular Communication | Inflammation surrounding the vertebral spinous processes as spondylarthritis in Behcet's disease. | 22797948 |
| Inflammation, Behcet Syndrome | Altered Intercellular Communication | Here, we present two Behcet's disease (BD) patients with an uncommon complication: inflammation surrounding the spinous processes revealed by positron emission tomography/computed tomography (PET/CT). | 22797948 |
| Inflammation, Spanish Language, Spondylarthritis | Altered Intercellular Communication | However, inflammation around the spinous processes should be regarded as a possible uncommon finding of seronegative spondyloarthropathy (SpA) in BD patients. | 22797948 |
| Pleurisy, Fever, CTCAE, Autosomal recessive inheritance, Brucellosis | Altered Intercellular Communication | Familial Mediterranean fever is an autosomal recessive disease characterized by recurrent fever and peritoneal and pleural inflammation. | 22798132 |
| Inflammation | Altered Intercellular Communication | Dissociation of pentameric CRP (pCRP) into pro-inflammatory monomers (mCRP) may directly link CRP to inflammation. | 22798388 |
| Vascular Diseases, Mucopolysaccharidosis I | Altered Intercellular Communication | MPs containing mCRP were able to bind to the surface of endothelial cells and generate pro-inflammatory signals in vitro, suggesting a possible role of MPs in transport and delivery of pro-inflammatory mCRP in vascular disease. | 22798388 |
| Inflammation, Complications of Diabetes Mellitus | Altered Intercellular Communication | Therefore, periodontal therapy could influence metabolic control or systemic inflammation leading to diabetic complications. | 22799126 |
| Keratitis | Altered Intercellular Communication | The features and extent of corneal inflammation, degree of involvement of subbasal nerve plexus and endothelial cell density were evaluated. | 22799438 |
| Inflammation, Myasthenia Gravis | Altered Intercellular Communication | It significantly distinguished from myasthenia gravis (MG) and local non-specific inflammation (F = 24.46, P = 0.000). | 22800425 |
| Inflammation | Altered Intercellular Communication | In addition, from the view of concomitant symptoms, local aching was very frequent in local non-specific inflammation (all 60 cases) and MVI (44 cases) patients (Chi2 = 36.346, P = 0.000). | 22800425 |
| Inflammation | Altered Intercellular Communication | MG, MVI and local non-specific inflammation are the most frequent causes. | 22800425 |
| Primary malignant neoplasm | Altered Intercellular Communication | Interleukin-l7 (IL-17), which exerts strong pro-inflammatory effects, has emerged as an important mediator in inflammation-associated cancer. | 22800829 |
| Inflammation, Virus Diseases, Myocarditis, CTCAE 5.0 | Altered Intercellular Communication | Although 97% of children with clinically or biopsy-diagnosed myocarditis at presentation survived to transplantation, they had significantly higher posttransplantation mortality compared with children without myocarditis, raising the possibility that preexisting viral infection or inflammation adversely affects graft survival. | 22800850 |
| Nose Diseases, IL13 gene | Altered Intercellular Communication | Allergic rhinitis (AR) is a symptomatic disorder of the nose induced after allergen exposure by an IgE-mediated inflammation of the nasal mucosa. | 22801008 |
| Obstruction, Inflammatory disease of mucous membrane | Altered Intercellular Communication | These results suggest a relationship between nasal temperature and nasal mucosa inflammation and obstruction. | 22801008 |
| Inflammation, Craniosynostosis | Altered Intercellular Communication | A combination of oral and nasal FeNO measurements is useful to monitor the extent of inflammation in CRS patients. | 22801009 |
| Airway structure, Craniosynostosis | Altered Intercellular Communication | Reduction of oral FeNO levels may reflect a cessation of the underlying lower airway inflammation that is characteristic of ECRS. | 22801009 |
| Inflammation, Coronary Arteriosclerosis | Altered Intercellular Communication | Research has found evidence that chronic inflammation may promote atherosclerotic disease. | 22801014 |
| Inflammation, Tuberculosis | Altered Intercellular Communication | The result of pathologic examination was reported as caseating granulomatous inflammation compatible with tuberculosis. | 22801175 |
| Inflammatory disease of mucous membrane, Cervical Intraepithelial Neoplasia | Altered Intercellular Communication | Cervical intraepithelial neoplasia is associated with genital tract mucosal inflammation. | 22801340 |
| Inflammation | Altered Intercellular Communication | The observed mucosal inflammation suggests a mechanism that may also contribute to the epidemiologic link between persistent HPV and HIV. | 22801340 |
| Hemangioma | Altered Intercellular Communication | Accuracy rates of them were not different in hemangioma (P=0.277) and infection-inflammation (P=0.470). | 22801441 |
| Hemangioma of liver, Fatty degeneration | Altered Intercellular Communication | Small needles can be successfully used as well as large ones in focal steatosis, infection-inflammation, and hemangioma of liver in unclear diagnosis. | 22801441 |
| Pulmonary Embolism | Altered Intercellular Communication | The possibility that pulmonary embolism arises de novo in the lungs, due to local inflammation-driven coagulation, needs to be considered. | 22801962 |
| Inflammation, Fibrosis Assessment, Retractile Mesenteritis | Altered Intercellular Communication | Histopathology of the mesentery and omentum showed chronic inflammation and fibrosis, supporting a diagnosis of sclerosing mesenteritis. | 22802373 |
| Infection, prostatitis | Altered Intercellular Communication | Prostatic inflammation is associated with infections penetrating through the urethra. | 22803119 |
| Calcinosis, atherosclerotic | Altered Intercellular Communication | These data suggest that while an intervention of this nature improves vascular tone, it does not exert significant effects on serum biomarkers related to atherosclerotic inflammation and calcification. | 22803952 |
| Inflammation, Nasal Polyps, Chronic sinusitis | Altered Intercellular Communication | However, little is known about how LPS regulates pathogenesis of chronic rhinosinusitis with nasal polyps, a major form of eosinophilic inflammation in the upper airway. | 22805469 |
| Asthma, MS4A2 wt Allele, Bronchitis | Altered Intercellular Communication | To explore the association of different adiposity types with self-reported asthma, bronchial inflammation and lung function, accounting for possible effect modifiers, such as atopy and gender. | 22805471 |
| Inflammation | Altered Intercellular Communication | Of the 35 patients, 33 (94%) had at least one MD-CTE finding of active or chronic pouch inflammation and 27 patients (77%) had at least one MD-CTE finding of active pouch inflammation. | 22805666 |
| Inflammation | Altered Intercellular Communication | In patients who had IPAA surgery, findings on MD-CTE correlate positively with findings on pouch endoscopy and histopathology and are sensitive measures for pouch inflammation with high positive predictive value. | 22805666 |
| Inflammation, Obesity | Altered Intercellular Communication | Systemic inflammation in childhood obesity: circulating inflammatory mediators and activated CD14++ monocytes. | 22806355 |
| Inflammation | Altered Intercellular Communication | Muscle characteristics in patients with chronic systemic inflammation. | 22806369 |
| Inflammation, Muscular Atrophy | Altered Intercellular Communication | There is increasing clinical evidence for a strong correlation between chronic systemic inflammation and age-related muscle wasting. | 22806369 |
| Refractory anemias, Inflammation, Rheumatoid Arthritis, Degenerative polyarthritis | Altered Intercellular Communication | As a model for chronic systemic inflammation, we included 10 patients suffering from rheumatoid arthritis (RA) and 27 control patients suffering from osteoarthritis (OA). | 22806369 |
| Refractory anemias, Inflammation | Altered Intercellular Communication | These results suggest there is no association between chronic systemic inflammation in RA and age-related muscle characteristics. | 22806369 |
| Hepatic inflammation, fibrogenesis | Altered Intercellular Communication | Here we studied TGFb as well as other factors produced by HCV-specific intrahepatic lymphocytes (IHL) and peripheral blood cells in hepatic inflammation and fibrogenesis. | 22806830 |
| Fibrosis Assessment, Hepatitis | Altered Intercellular Communication | HCV-specific TGFb, not interleukin (IL)-10, inversely correlated with liver inflammation (R = -0.63, P = 0.008) and, unexpectedly, fibrosis (R = -0.46, P = 0.05). | 22806830 |
| Inflammation, Hyperplasia | Altered Intercellular Communication | This finding has been associated with either inflammation or hyperplasia in prior case series. | 22807581 |
| Inflammation, Brain Injury, Chronic | Altered Intercellular Communication | Despite a lack of a specific etiologic agent, evidence suggests multinucleated epithelial giant cells are the consequence of inflammation, chronic injury, or cellular degeneration. | 22807581 |
| HD Term Type, Inflammation, hepcidin | Altered Intercellular Communication | In conclusion, in the currently studied cohort of chronic HD patients, hepcidin-25 was a marker for iron stores and erythropoiesis and was associated with inflammation. | 22808058 |
| Inflammation, Cardiovascular Diseases | Altered Intercellular Communication | Physical activity (PA) is beneficial to overall health, in part due to physiological changes that lower risk factors for cardiovascular disease, including reduced inflammation. | 22808178 |
| Inflammation, Carcinogenesis, Adenomatous Polyps | Altered Intercellular Communication | Expression of Abelson interactor 1 (Abi1) correlates with inflammation, KRAS mutation and adenomatous change during colonic carcinogenesis. | 22808230 |
| Inflammatory Bowel Diseases, Crohn Disease, Inflammatory disease of mucous membrane | Altered Intercellular Communication | Clinical observations suggest that the lymphoid follicles (LFs) may play a crucial role in the pathogenesis of inflammatory bowel disease (IBD), especially in Crohn's disease (CD) as the site of initial mucosal inflammation. | 22808293 |
| Inflammation, Stricture of bile duct, Fibrosis Assessment, Primary sclerosing cholangitis, Bile Duct Neoplasms | Altered Intercellular Communication | Primary sclerosing cholangitis (PSC), which is characterized by inflammation and fibrosis and may lead to bile duct stricture over the intrahepatic or extrahepatic bile duct, is rare in children. | 22808613 |
| Inflammatory Bowel Diseases, Inflammation | Altered Intercellular Communication | Chronic inflammation in IBD is accompanied by an imbalance in the production of TX1 and Th2 cytokines. | 22808797 |
| Inflammation, Rupture, Coronary Artery Disease, Endothelial dysfunction, Dental Plaque | Altered Intercellular Communication | Inflammation plays an important role in coronary artery disease from the initiation of endothelial dysfunction to plaque formation to final rupture of the plaque. | 22809439 |
| Inflammation, Metabolic Syndrome X, ETV3 wt Allele, Cardiovascular Diseases | Altered Intercellular Communication | Increasing evidence suggests that chronic, low-grade inflammation may be a common soil involving the pathogenesis of metabolic syndrome (MetS) and cardiovascular disease. | 22810425 |
| ARCN1 gene, Inflammation, Chronic Obstructive Airway Disease | Altered Intercellular Communication | Low-grade systemic inflammation, particularly elevated IL-6, predicts mortality in chronic obstructive pulmonary disease (COPD). | 22811442 |
| ARCN1 gene, Inflammation | Altered Intercellular Communication | Although altered body composition, especially increased visceral fat (VF) mass, could be a significant contributor to low-grade systemic inflammation, this remains unexplored in COPD. | 22811442 |
| Inflammation, Endothelial dysfunction | Altered Intercellular Communication | Cross-sectional associations between job strain and serum biomarkers of inflammation and endothelial dysfunction were investigated. | 22813435 |
| Inflammation | Altered Intercellular Communication | Secondary analyses explored the role of psychosocial/cardiometabolic risk factors as mediators of job stress associated inflammation in healthy workers. | 22813435 |
| Kidney Failure, Chronic, Inflammation, Cachexia | Altered Intercellular Communication | Protein-energy wasting and chronic inflammation are prevalent in patients with end-stage renal disease (ESRD). | 22813921 |
| Inflammation | Altered Intercellular Communication | An initial set of skin punch biopsies revealed extensive palisading granulomatous inflammation throughout the dermis, extending into the subcutis. | 22814320 |
| Arterial Stiffness, Inflammation | Altered Intercellular Communication | Pulsatile stress, inflammation and change in arterial stiffness. | 22814403 |
| Arterial Stiffness, Inflammation | Altered Intercellular Communication | These results demonstrate that both pulsatile stress and inflammation may be associated with arterial stiffness at any given moment in time, but change in pulsatile stress is a better predictor of change in arterial stiffness over time. | 22814403 |
| Wounds and Injuries | Altered Intercellular Communication | Chronic irritation of the skin, traumatic injury, and hormonal alterations seem to be implicated in the pathogenesis of PG. | 22814624 |
| Inflammation, Chronic disease, Metabolic Syndrome X, Obesity | Altered Intercellular Communication | Oxidative stress is associated with obesity, metabolic syndrome and inflammation, suggesting it could be an early event in the pathology of chronic diseases. | 22816656 |
| Inflammation, Malnutrition, Dyslipidemias, Atherosclerosis | Altered Intercellular Communication | In hemodialysis (HD) patients, dyslipidemia, malnutrition, inflammation and atherosclerosis are common. | 22817124 |
| Inflammation, Chronic Kidney Diseases | Altered Intercellular Communication | Chronic kidney disease progression has been linked to pro-inflammatory cytokines and markers of inflammation. | 22817530 |
| Kidney Failure, Chronic, Inflammation | Altered Intercellular Communication | Our preliminary data suggest that four genetic polymorphisms located in genes related to inflammation and immune processes could help to predict the risk of developing ESRD. | 22817530 |
| Inflammation, Cyclophosphamide/Vincristine/Dacarbazine Regimen, Cardiovascular Diseases | Altered Intercellular Communication | Severe mental disorder and cardiovascular disease (CVD) are often associated, and inflammation is implicated in both disorders. | 22817875 |
| Inflammation, Schizophrenia, Bipolar Disorder | Altered Intercellular Communication | We investigated whether there is a relationship between CVD risk factors and inflammation in schizophrenia or bipolar disorder, and if second generation antipsychotics (SGA) interact. | 22817875 |
| Inflammation, Inflammatory disorder | Altered Intercellular Communication | The development of paradoxical inflammation in immune-mediated inflammatory diseases patients treated with anti TNF-a suggests that an unknown inflammatory pathway may be provoked by inhibiting TNF-a. | 22818164 |
| Inflammation, Bacterial Infections | Altered Intercellular Communication | Postmortem biochemical investigations confirmed the presence of inflammation associated with local bacterial infection. | 22819527 |
| Inflammation, Neck Soft Tissue Necrosis, CTCAE, Rupture of artery | Altered Intercellular Communication | Acute and chronic inflammation with tissue necrosis as well as post-actinic, fibrotic changes were also found in the tissues surrounding the ruptured artery wall. | 22819527 |
| Inflammation, Overweight | Altered Intercellular Communication | Lycopene intervention reduces inflammation and improves HDL functionality in moderately overweight middle-aged individuals. | 22819555 |
| Inflammation, Overweight | Altered Intercellular Communication | The management of overweight subjects by interventions aimed at reducing inflammation is highly desirable. | 22819555 |
| Inflammation | Altered Intercellular Communication | Therefore, this study examined lycopene's ability to lower systemic and high-density lipoprotein (HDL)-associated inflammation in moderately overweight middle-aged subjects. | 22819555 |
| Inflammation | Altered Intercellular Communication | Tissue inhibitor of metalloproteinases (TIMP)-3 is an inhibitor of matrix metalloproteinases, which regulates tissue inflammation, damage, and repair. | 22819866 |
| Gastrointestinal inflammation | Altered Intercellular Communication | We investigated the role of TIMP-3 in intestinal inflammation in human beings and mice. | 22819866 |
| Degenerative polyarthritis, Inflammation | Altered Intercellular Communication | To compare inflammation as assessed by ultrasound between patients with the subset erosive hand osteoarthritis (EOA) versus non-EOA. | 22820060 |
| Inflammation, Rheumatoid Arthritis | Altered Intercellular Communication | Levels of inflammation after treatment with TNFa antagonists are significantly associated with ADMA levels in patients with rheumatoid arthritis. | 22820438 |
| Inflammation, Infectious Endophthalmitis | Altered Intercellular Communication | Among 219 consecutive cases of 186 patients who had undergone IVTA injection for macular diseases, presumed noninfectious endophthalmitis was diagnosed if the patient showed severe inflammation in the anterior chamber and vitreous cavity within 7 days after injection but no organism was isolated on microbiological examination. | 22820815 |
| Degenerative polyarthritis, Inflammation, Clostridium | Altered Intercellular Communication | The decrease in Clostridia, a potent modulator of colonic Th17 and CD4+ regulatory T cells, was consistent with a decrease in inflammation; improved GSRS scores and OA symptoms for these OA participants. | 22821424 |
| Inflammation, Neurologic Dysfunction, Edema, Cell Death, Traumatic injury | Altered Intercellular Communication | Perturbation of neurovascular homeostasis causing oedema, inflammation and cell death is an important cause of acute and long-term neurological dysfunction after trauma. | 22822039 |
| ARCN1 gene, Inflammation | Altered Intercellular Communication | The aim of this work is to investigate if there was any correlation between inflammation factors and severity of COPD. | 22822613 |
| ARCN1 gene, Inflammation | Altered Intercellular Communication | Attenuation of systemic inflammation may offer new perspectives in the management of COPD and its comorbidities. | 22822613 |
| Neoplasms | Altered Intercellular Communication | Solitary paraspinal masses in the pediatric age group commonly occur secondary to spinal dysraphism, chronic inflammatory conditions, and tumors. | 22823460 |
| Refractory anemias, Inflammation | Altered Intercellular Communication | The most common lipid abnormality in RA is reduced levels of high-density lipoprotein (HDL) cholesterol, probably due to active inflammation. | 22824166 |
| Alzheimers Disease", Data types - Address | Altered Intercellular Communication | This study undertakes a systematic and comprehensive analysis of brain gene expression profiles of immune/inflammation-related genes in aging and Alzheimer's disease (AD). | 22824372 |
| Data types - Address | Altered Intercellular Communication | First, immune/inflammation-related genes showed major changes in gene expression over the course of cognitively normal aging, with the extent of gene response far greater in aging than in AD. | 22824372 |
| Data types - Address | Altered Intercellular Communication | In contrast, far fewer immune/inflammation genes were significantly changed in the transition to AD (approximately 6% of immune-related probesets), with gene responses primarily restricted to the SFG and HC. | 22824372 |
| Data types - Address | Altered Intercellular Communication | Second, relatively few significant changes in immune/inflammation genes were detected in the EC either in aging or AD, although many genes in the EC showed similar trends in responses as in the other brain regions. | 22824372 |
| Data types - Address | Altered Intercellular Communication | Third, immune/inflammation genes undergo gender-specific patterns of response in aging and AD, with the most pronounced differences emerging in aging. | 22824372 |
| Inflammation, Data types - Address | Altered Intercellular Communication | Unexpectedly, the extent of innate immune gene upregulation in AD was modest relative to the robust response apparent in the aged brain, consistent with the emerging idea of a critical involvement of inflammation in the earliest stages, perhaps even in the preclinical stage, of AD. | 22824372 |
| Inflammation | Altered Intercellular Communication | Elevated plasma suPAR concentration is associated with increased mortality in various patient groups, and it is speculated that suPAR is a low-grade inflammation marker reflecting on disease severity. | 22824423 |
| Inflammation, Chronic disease | Altered Intercellular Communication | Asthma, especially among children aged 7-16 years, is usually a chronic disease and should, in many cases, be treated with anti-asthmatics counteracting inflammation. | 22824566 |
| Acute Lung Injury, Pneumonitis, Blood Coagulation Disorders | Altered Intercellular Communication | Transfusion-related acute lung injury in cardiac surgery patients is characterized by pulmonary inflammation and coagulopathy: a prospective nested case-control study. | 22824931 |
| Inflammation, Observation Method - Coagulation, Transfusion-Related Acute Lung Injury | Altered Intercellular Communication | The objective of the present study was to determine inflammation and coagulation pathways involved in the onset of transfusion-related acute lung injury. | 22824931 |
| Inflammation | Altered Intercellular Communication | In all patients, cardiac surgery was associated with systemic inflammation, evidenced by an increase in plasma levels of interleukin-6, interleukin-8, and elastase-a1-antitrypsin complexes compared with presurgery levels (p<.001). | 22824931 |
| Inflammation, Transfusion-Related Acute Lung Injury | Altered Intercellular Communication | Prior to onset of transfusion-related acute lung injury, there is systemic inflammation and neutrophil sequestration. | 22824931 |
| Acute Lung Injury, Pneumonitis | Altered Intercellular Communication | Transfusion-related acute lung injury is characterized by both systemic and pulmonary inflammation and activation of neutrophils, as well as enhanced coagulation and suppressed fibrinolysis. | 22824931 |
| Inflammation, Hepatic Vein Thrombosis, Pancreatitis, Alcoholic, Thrombophilia | Altered Intercellular Communication | Extrahepatic portal venous system thrombosis in recurrent acute and chronic alcoholic pancreatitis is caused by local inflammation and not thrombophilia. | 22825367 |
| Communicable Diseases, Inflammation, Traumatic injury, Rupture | Altered Intercellular Communication | The case of a patient who underwent an endovascular aortic repair for a spontaneous rupture of a non-aneurysmal subdiaphragmatic aorta without trauma, infection, or inflammation is reported. | 22825863 |
| Inflammation, Angina Pectoris | Altered Intercellular Communication | The independent relationship between systemic inflammation and fragmented QRS complexes in patients with stable angina pectoris. | 22825938 |
| Immediate-type hypersensitivity drug reaction, Airway structure | Altered Intercellular Communication | Challenge with K(2)PtCl(4) by a dosimeter method yielded a clear immediate-type reaction with an increase of exhaled nitric oxide from 32 to 156 ppb after 24 h indicating an increased airway inflammation. | 22826048 |
| Pleural Effusion, CTCAE, Pleurisy, Atelectasis | Altered Intercellular Communication | Chest X-ray revealed lower left lobe consolidation with pleural inflammation and chest CT showed extensive interstitial-alveolar changes in the left lung with atelectasis and pleural effusion causing a reduction in lung volume up to the fourth rib. | 22826075 |
| Bacteremia, HD Term Type, Inflammation | Altered Intercellular Communication | We retrospectively collected clinical data and healthcare costs from 15 months for 75 admitted catheter-dependent HD patients, to document the type of bacteremia (complicated or not), pathogen and inflammation. | 22826145 |
| Bacteremia, Inflammation, Anemia | Altered Intercellular Communication | Although, in patients starting dialysis on catheter (41 %) as compared to those using catheter as bridge angioaccess, inflammation (higher C-reactive protein; p = 0.006) and anemia (lower Hb; p = 0.008) were more pronounced, bacteremia occurred in a lower proportion (32 vs. 64 %, p = 0.007). | 22826145 |
| Inflammation, Malignant Neoplasms | Altered Intercellular Communication | Pathological examination demonstrated active inflammation with no evidence of malignancy. | 22826630 |
| Primary malignant neoplasm, Chronic inflammation | Altered Intercellular Communication | If cancer follows chronic inflammation, immunosuppression, or it is pure coincidence, is still a matter of debate. | 22826971 |
| Autoimmune Diseases, Inflammation | Altered Intercellular Communication | Recent studies have suggested that TH17 cells and its signature cytokine IL-17 are involved in the underlying pathogenic mechanisms leading to destructive inflammation and autoimmunity. | 22827855 |
| Inflammation, Glaucoma, CTCAE | Altered Intercellular Communication | Furthermore, the surgical success of glaucoma filtering surgery is compromised in patients with scarring and inflammation of the conjunctiva. | 22828007 |
| Inflammation, Compression, Swelling | Altered Intercellular Communication | Adhesiolysis was developed as a means of removing epidural scarring leading directly or indirectly to compression, inflammation, swelling, or a decreased nutritional supply of nerve roots. | 22828693 |
| Refractory anemias, Rheumatoid Arthritis, Autoimmune Diseases, Inflammation | Altered Intercellular Communication | Rheumatoid arthritis (RA) is a chronic, systemic and an autoimmune disease characterized by inflammation of the synovial membrane that affects approximately 1 % of the total world population. | 22829412 |
| ARCN1 gene, Inflammation | Altered Intercellular Communication | The etiology of COPD has been associated with apoptosis, oxidative stress, and inflammation. | 22829758 |
| Inflammatory Bowel Diseases, Inflammation | Altered Intercellular Communication | Chronic inflammation in IBD is accompanied by an imbalance in the production of Tx1 and Tx2 cytokines. | 22830224 |
| Necrotizing granulomatous inflammation, T-Cell Lymphoma, Hodgkin Disease | Altered Intercellular Communication | Cutaneous granulomatous inflammation can occur in patients with T-cell lymphoma and Hodgkin disease. | 22830642 |
| Histiocytosis, Granulomatous inflammation | Altered Intercellular Communication | Histopathology showed GA-like palisaded histiocytic infiltration, with subtle collections of lymphocytes interspersed among the granulomatous inflammation. | 22830642 |
| Granulomatous inflammation, Infiltration | Altered Intercellular Communication | Co-existence of a GA-like infiltrate and cutaneous B-CLL raises the possibility that granulomatous inflammation occurs as a secondary response to dermal infiltration by leukemic cells. | 22830642 |
| Inflammation, Cyclophosphamide/Vincristine/Dacarbazine Regimen, Cardiovascular Diseases | Altered Intercellular Communication | Inflammation plays a role in the development of cardiovascular disease (CVD). | 22831953 |
| Inflammation, Obesity | Altered Intercellular Communication | Many inflammation parameters are associated with obesity, but few comparable data are found in youth. | 22832157 |
| Inflammation, Arthritis | Altered Intercellular Communication | Interleukin 1b (IL-1b) plays a central role in the pathogenesis of inflammation induced by calcium pyrophosphate crystals, and IL-1b blockade may be an effective treatment in patients with severe chronic calcium pyrophosphate crystal arthritis. | 22832289 |
| Airway structure, ARCN1 gene, Chronic Obstructive Airway Disease | Altered Intercellular Communication | Matrix metalloproteinase-9 (MMP-9) and its inhibitor tissue inhibitor of metalloproteinase-1 (TIMP-1) are involved in the pathogenesis of airway inflammation in patients with chronic obstructive pulmonary disease (COPD). | 22832426 |
| Airway structure | Altered Intercellular Communication | However, no study so far has addressed their value as noninvasive biomarkers of airways inflammation. | 22832426 |
| ARCN1 gene, Airway structure | Altered Intercellular Communication | Exhaled MMP-9 and TIMP-1 increased during COPD exacerbation and was negatively correlated with spirometric variables, which suggests the usefulness of their measurement in EBC for the monitoring of airways inflammation. | 22832426 |
| Depressive disorder, Inflammation, Depression, CTCAE | Altered Intercellular Communication | Association of depressive disorders, depression characteristics and antidepressant medication with inflammation. | 22832816 |
| Inflammation, Depressed mood, Depression, CTCAE | Altered Intercellular Communication | After full adjustment, highest inflammation levels were found in depressed men with an older age of depression onset (CRP, TNF-a). | 22832816 |
| Inflammation, Depressed mood | Altered Intercellular Communication | In conclusion, elevated inflammation was confirmed in depressed men, especially those with a late-onset depression. | 22832816 |
| Autoimmune Diseases, Inflammation, Lupus Erythematosus, Lupus Erythematosus, Systemic | Altered Intercellular Communication | Systemic lupus erythematosus (SLE) is a chronic autoimmune disease characterized by the presence of autoantibodies and inflammation in multiple organ systems. | 22833362 |
| Inflammation, Cardiovascular Diseases, Obesity, Diabetes Mellitus | Altered Intercellular Communication | As discussed, understanding Hcy and genetic regulation is important, because Hcy may be related to inflammation, obesity, cardiovascular disease, and diabetes mellitus. | 22833659 |
| Inflammation, Hypertension, CTCAE | Altered Intercellular Communication | Red cell distribution width and inflammation in patients with non-dipper hypertension. | 22835009 |
| Inflammation, Hypertension, CTCAE | Altered Intercellular Communication | Non-dipper hypertension is associated with higher inflammation and worse prognosis. | 22835009 |
| Inflammation, Primary malignant neoplasm, Cardiovascular Diseases | Altered Intercellular Communication | Leukotrienes (LT) play a role in inflammation, cardiovascular diseases, and cancer. | 22835628 |
| Hyperhomocysteinemia, Arteriosclerosis Obliterans | Altered Intercellular Communication | [Inflammation of the vascular wall and hyperhomocysteinemia in patients with atherosclerosis obliterans of lower limb arteries]. | 22836325 |
| Inflammation, Hyperhomocysteinemia, Ischemia, Endothelial dysfunction, Vasculitis | Altered Intercellular Communication | The comparative analysis revealed that patients with LLA had signs of chronic vascular inflammation accompanied in the majority of cases by hyperhomocysteinemia with endothelial dysfunction, as well as direct association between the degree of the vascular inflammatory reaction and severity of clinical manifestations of lower limb ischaemia. | 22836325 |
| ARCN1 gene, Chronic Obstructive Airway Disease | Altered Intercellular Communication | Chronic obstructive pulmonary disease (COPD) is characterized by progressive airflow limitation and chronic inflammation of airways and lung parenchyma. | 22836613 |
| ARCN1 gene, Chronic Obstructive Airway Disease | Altered Intercellular Communication | Chronic obstructive pulmonary disease (COPD) is a progressive, inflammatory condition, involving airways and lung parenchyma. | 22836615 |
| Abnormality of the vasculature, Neoplasms | Altered Intercellular Communication | Orbital lesions include a broad spectrum of tumors, vascular abnormalities, and inflammatory conditions. | 22836792 |
| Pulmonary Emphysema, Pneumonitis | Altered Intercellular Communication | Assessment of pulmonary neutrophilic inflammation in emphysema by quantitative positron emission tomography. | 22837375 |
| ARCN1 gene, Chronic Obstructive Airway Disease | Altered Intercellular Communication | Neutrophilic inflammation is understood to be of pathogenetic importance in chronic obstructive pulmonary disease (COPD) and may be quantified using 18-fluorodeoxyglucose positron emission tomography-computed tomography ((18)FDG PET-CT) as a noninvasive, spatially informative biomarker. | 22837375 |
| ARCN1 gene, Pneumonitis, alpha 1-Antitrypsin Deficiency | Altered Intercellular Communication | To assess the potential usefulness of (18)FDG PET-CT as a surrogate measure of pulmonary neutrophilic inflammation in patients with usual COPD and a(1)-antitrypsin deficiency (AATD). | 22837375 |
| Inflammation, alpha 1-Antitrypsin Deficiency | Altered Intercellular Communication | (18)FDG uptake, lung physiology, lung density, and systemic markers of inflammation were compared for all groups at baseline and, in patients with AATD, at baseline and on treatment. | 22837375 |
| Inflammation, Hyphema | Altered Intercellular Communication | After resolution of hyphema, transient elevated intraocular pressure, and anterior chamber inflammation, best corrected visual acuity returned to 20/25 in each eye 6 months later. | 22837630 |
| Lichen Planus | Altered Intercellular Communication | Lichen planus is an autoimmune inflammatory condition in which autoreactive T lymphocytes attack keratinocytes. | 22838091 |
| Tolosa-Hunt Syndrome, Inflammation, Methylated spirit, Orbital fissure | Altered Intercellular Communication | Tolosa-Hunt syndrome (THS) is an uncommon disease caused by non-specific inflammation of the cavernous sinus, superior orbital fissure and the apex of the orbit. | 22838177 |
| Inflammation, Periodontal Diseases, Treponema | Altered Intercellular Communication | The relationship between different species of oral Treponemas and inflammation in periodontal disease progression is complex. | 22838219 |
| Inflammation, Pneumonia, Interstitial, Hyperplasia, Idiopathic Pulmonary Fibrosis | Altered Intercellular Communication | Idiopathic pulmonary fibrosis (IPF) is a devastating interstitial pneumonia causing a loss of respiratory surface area due to a proliferative fibrotic response involving hyperplastic, hypertrophic, and metaplastic epithelium, cystic honeycomb change, septal expansion, and variable inflammation. | 22838404 |
| Refractory anemias, Rheumatoid Arthritis, Inflammation | Altered Intercellular Communication | The increased risk of cardiovascular (CV) disease associated with rheumatoid arthritis (RA) is partly attributable to chronic inflammation, but traditional CV risk factors such as physical inactivity are also likely to be important. | 22839595 |
| Inflammation, atherosclerotic | Altered Intercellular Communication | Cytokines as regulators of activity of inflammation play significant role in mechanisms of formation of atherosclerotic plaques and in processes of their destabilization. | 22839710 |
| Inflammation, Fibrosis Assessment, ETV3 wt Allele | Altered Intercellular Communication | The current demonstration that MetS is associated with decrease of the pro-fibrotic PDGF cytokine is a completely novel finding, which adds complexity to the interplay between inflammation and fibrosis in patients affected by MetS. | 22840561 |
| Inflammation | Altered Intercellular Communication | Initially performed MRI of the pelvis shows predominant inflammation of the hip joint. | 22840961 |
| Immune-mediated | Altered Intercellular Communication | Accumulating evidence suggests that immune-mediated inflammation plays an important role in the pathophysiology of AMI, but the mechanism that triggers such immune responses is unknown. | 22841473 |
| Inflammation, Prediabetes syndrome | Altered Intercellular Communication | The obtained results suggest that metformin may inhibit monocyte secretory function and reduce systemic inflammation in statin-treated patients with prediabetes. | 22841520 |
| Dental Plaque | Altered Intercellular Communication | Inflammation within atheromatous plaques is a known risk factor for plaque vulnerability. | 22841932 |
| Autosomal Recessive Disorder, Inflammation, Fever, CTCAE, Brucellosis | Altered Intercellular Communication | Familial Mediterranean fever is an autosomal recessive disorder characterized by paroxysmal episodes of fever and serosal inflammation. | 22842301 |
| Inflammation, Diabetes Mellitus, Non-Insulin-Dependent, Cardiovascular Diseases | Altered Intercellular Communication | Resistin is a polypeptide hormone that was reported to be associated with insulin resistance, inflammation and risk of type 2 diabetes and cardiovascular disease. | 22843503 |
| Inflammation, Diabetes Mellitus, Non-Insulin-Dependent, Cardiovascular Diseases | Altered Intercellular Communication | Resistin is a polypeptide hormone that was reported to be associated with insulin resistance, inflammation and risk of type 2 diabetes and cardiovascular disease. | 22843503 |
| Inflammation, Colorectal Carcinoma | Altered Intercellular Communication | Nuclear factor-kappa B (NFkB) is a major regulator of inflammation and variation in NFkB-associated genes could potentially be used as biomarkers to identify patients with increased risk of colorectal cancer (CRC) development, and/or a rapidly progressing disease. | 22843550 |
| Malignant neoplasm of urinary bladder | Altered Intercellular Communication | Utility of inflammation-based prognostic scoring in patients given systemic chemotherapy first-line for advanced inoperable bladder cancer. | 22844127 |
| Inflammation, Cicatricial ectropion | Altered Intercellular Communication | The eyelid inflammation decreased but severe scarring of the marginal eyelids persisted, resulting in cicatricial ectropion. | 22845188 |
| HD Term Type, Cardiac complication, Inflammation | Altered Intercellular Communication | Chronic inflammation in hemodialysis (HD) patients is associated with cardiovascular complications and mortality. | 22845695 |
| HD Term Type, Inflammation | Altered Intercellular Communication | We intended to test the feasibility of using a high cutoff (HCO) dialyzer in chronic HD patients and its influence on inflammation and monocyte activation. | 22845695 |
| Inflammation, Infant, Premature | Altered Intercellular Communication | In the rLD and sVD/PD groups, risk factors, such as prematurity and fetal inflammation, co-existed. | 22845749 |
| Inflammation | Altered Intercellular Communication | On the other hand, old birds showed imbalanced levels of inflammatory markers toward a pro-inflammatory status, thereby underlining the fact that aging is usually accompanied by systemic inflammation and inflammation-related chronic diseases. | 22846077 |
| Inflammation | Altered Intercellular Communication | We report here two cases of fatal lime sulfide poisoning with several related cases and in addition induced histological damage with acute inflammation in animal models under at similar concentrations. | 22847057 |
| Inflammation, Malaria, Anemia | Altered Intercellular Communication | We found high prevalence of anemia, malaria, inflammation, and deficiencies of iron, riboflavin, and vitamin A but low prevalence and intensities of soil-transmitted helminth and schistosome infections. | 22848097 |
| Inflammation, Fibrosis Assessment | Altered Intercellular Communication | Myocardial biopsies from Apoe(-/-) mice demonstrated signs of chronic inflammation with fibrosis, increased apoptosis and expression of IL-6, as compared to biopsies from C57BL/6J control mice. | 22848603 |
| Neoplasms | Altered Intercellular Communication | Tumor and stroma are additional sources of inflammation-related molecules. | 22848630 |
| Carcinogenesis, Colorectal Carcinoma, Adenoma of large intestine | Altered Intercellular Communication | Combined quantification of serum IL-8, MMP-9 and CRP, appears a reliable and advanced index of inflammation-related processes during malignant phase of colorectal carcinogenesis, since these molecules remain within normal range in colorectal adenoma bearing patients, while consistently increase in the blood of CRC patients, even if from stage II only. | 22848630 |
| Extrinsic allergic alveolitis, Granulomatous inflammation, Pneumonia, Interstitial, Chronic bronchiolitis | Altered Intercellular Communication | Her biopsy showed honeycomb change and fibroblast foci suggestive of usual interstitial pneumonia, but also showed areas of cellular interstitial pneumonia with chronic bronchiolitis and a pattern of granulomatous inflammation typical of hypersensitivity pneumonia. | 22849736 |
| Myocarditis | Altered Intercellular Communication | Different etiologies of pericardial inflammation did not influence the IFN-gamma levels. | 22850905 |
| Inflammation, Prostate carcinoma | Altered Intercellular Communication | Genetic factors regulating inflammation and DNA methylation associated with prostate cancer. | 22850906 |
| Inflammation, Prostate carcinoma, Structure of posterior cerebral artery | Altered Intercellular Communication | Prostate cancer (PCa) displays a strong familiarity component and genetic factors; genes regulating inflammation may have a pivotal role in the disease. | 22850906 |
| Inflammation, Lupus Erythematosus, Systemic | Altered Intercellular Communication | The complement system plays an important role in tissue inflammation and damage in SLE patients. | 22851413 |
| Celiac Disease, Stenosis | Altered Intercellular Communication | SBCE findings were classified as clinically significant/sinister (small-bowel malignancy, significant/sinister inflammation and/or strictures and coeliac disease) or vascular, i.e., signifcant/angioectasias (P1/P2 lesions). | 22852553 |
| Inflammation, Primary malignant neoplasm, Depression, CTCAE | Altered Intercellular Communication | Interrelationship of depression, stress and inflammation in cancer patients: a preliminary study. | 22854100 |
| Inflammation, Aortic Aneurysm, Abdominal | Altered Intercellular Communication | Inflammation in the walls of asymptomatic abdominal aortic aneurysms is not associated with increased metabolic activity detectable by 18-fluorodeoxglucose positron-emission tomography. | 22854268 |
| Inflammation | Altered Intercellular Communication | The chronic inflammation observed in the wall of asymptomatic AAAs was not sufficiently metabolically active to result in an increased glucose metabolism detectable by FDG-PET by means of this standard protocol. | 22854268 |
| Inflammation, Primary malignant neoplasm | Altered Intercellular Communication | Neutrophil to lymphocyte ratio (NLR), an index of systemic inflammation, has been associated with worse survival for many types of cancer. | 22855161 |
| Inflammation, Fever, CTCAE, Hypertrophy | Altered Intercellular Communication | They were affected by chronic hypertrophic tonsillitis with a recurrent fever and other symptoms that were related to oral inflammation. | 22855380 |
| Edema, Acute inflammation, Exudate | Altered Intercellular Communication | Minor complications included sore throat, moderate oedema, mild acute pharynx inflammation, slight peritonsillar exudate and local burning. | 22855380 |
| Inflammation, Plaque, Atherosclerotic | Altered Intercellular Communication | Targeted folate receptor b fluorescence imaging as a measure of inflammation to estimate vulnerability within human atherosclerotic carotid plaque. | 22855837 |
| Inflammation, Depression, CTCAE, Atherosclerosis | Altered Intercellular Communication | Inflammation and atherosclerosis play an important role in the pathogenesis of depression. | 22856651 |
| ARCN1 gene, Inflammation, Chronic Obstructive Airway Disease | Altered Intercellular Communication | One of the major pathophysiologies in advanced chronic obstructive pulmonary disease (COPD) has been attributed to systemic inflammation. | 22857881 |
| Dyssomnias, Inflammation, Primary malignant neoplasm, Depression, CTCAE | Altered Intercellular Communication | Sleep problems and depression are modifiable host factors that can influence inflammation and impact cancer progression and quality of life. | 22858235 |
| Electrocardiogram: myocardial infarction (finding), Ischemic stroke, Plaque, Atherosclerotic | Altered Intercellular Communication | Inflammation of an atherosclerotic plaque is a well-known risk factor in the development of ischemic stroke and myocardial infarction. | 22859280 |
| Inflammation, Dental Plaque | Altered Intercellular Communication | MR imaging is capable of characterizing inflammation by assessing plaque enhancement in both extracranial carotid arteries and coronary arteries. | 22859280 |
| Pain Distress Question, Inflammation, Primary gout | Altered Intercellular Communication | To evaluate the analgesic efficacy of high-dose celecoxib in the treatment of moderate to extreme pain and inflammation associated with acute gouty arthritis. | 22859357 |
| Pain Distress Question, Inflammation | Altered Intercellular Communication | Sympathetically maintained pain may occur when primary afferent neurons are excited by inflammation due to VZV infection. | 22860307 |
| Inflammation, Aggressive behavior, Hyponatremia | Altered Intercellular Communication | Furthermore, hyponatremia might be significantly associated with chronic inflammation and tumor aggressiveness. | 22860625 |
| Inflammation, zirconium oxide | Altered Intercellular Communication | No statistically significant difference in tissues adjacent to zirconia and titanium abutment surfaces were seen with respect to vascular density (20.5 SD 4.4 and 20.7 SD 3.2) or inflammation grading scale scores (3.2 SD 0.7 versus 3.1 SD 0.7). | 22862854 |
| Inflammation, Anemia, Chronic Kidney Diseases, Vitamin B 12 Deficiency | Altered Intercellular Communication | The five most prominent causes of anaemia were inflammation (62.1%), iron deficiency (30.5%), folic acid deficiency (21%), chronic renal failure (17.9%) and cobalamin deficiency (11.6%). | 22863429 |
| Inflammation, Acute Coronary Syndrome, Heart valve calcification | Altered Intercellular Communication | Association of serum fetuin-A levels with heart valve calcification and other biomarkers of inflammation among persons with acute coronary syndrome. | 22863558 |
| Inflammation, Hepatitis C, Liver Cirrhosis | Altered Intercellular Communication | The failure of the immune response to clear the Hepatitis C virus (HCV) results in chronic inflammation that leads to liver cirrhosis. | 22863720 |
| Inflammation, Calcification of coronary artery, SLC25A20 gene, Atherosclerosis | Altered Intercellular Communication | Several studies have demonstrated that inflammation plays a major role in the development of atherosclerosis and that the inflammatory process might also be involved in coronary artery calcification (CAC). | 22864317 |
| Diabetes Mellitus, Insulin-Dependent, Chronic inflammation | Altered Intercellular Communication | Systemic exposure to Pseudomonal bacteria: a potential link between type 1 diabetes and chronic inflammation. | 22864910 |
| Diabetic Nephropathy, Inflammation | Altered Intercellular Communication | Bacterial endotoxins have been associated with chronic inflammation and the development and progression of diabetic nephropathy. | 22864910 |
| Inflammation, Choroidal and Ciliary Body Melanoma pT1d TNM Finding v8 | Altered Intercellular Communication | These findings indicate that recurrent or chronic Pseudomonal exposure may increase susceptibility to chronic inflammation in patients with T1D. | 22864910 |
| Inflammation, Non-communicable Chronic Diseases, Cardiovascular Diseases | Altered Intercellular Communication | Low-grade chronic systemic inflammation is often associated with chronic non-communicable diseases, and its most frequently used marker, the C-reactive protein (CRP), has become an identifier of such diseases as well as an independent predictor for cardiovascular disorders and mortality. | 22865000 |
| Inflammation, Overweight, muscle mass | Altered Intercellular Communication | Intervention procedures to treat low-grade chronic inflammation in overweight women would mainly focus on restoring muscle mass and functions in addition to an antioxidant-rich diet. | 22865000 |
| Granulomatous Mastitis, Inflammation, Tuberculosis of breast | Altered Intercellular Communication | In 62 patients, there were benign lesions (fibroadenomas, fibrocysts), and four patients had inflammation (granulomatous mastitis in two patients, breast tuberculosis in two patients). | 22865198 |
| Inflammation | Altered Intercellular Communication | Yet, the role of inflammation following transcatheter aortic valve implantation (TAVI) has not been fully elucidated. | 22865312 |
| Communicable Diseases, Inflammation, Bacterial Infections | Altered Intercellular Communication | In intensive care unit (ICU) patients, signs of infection and inflammation are similar, making diagnosis of bacterial infections difficult. | 22865497 |
| Inflammation, Irritation, Dryness of eye, Eye pain | Altered Intercellular Communication | A number of ocular conditions, such as dry eye, are associated with inflammation on the surface of the eye leading to irritation and ocular pain. | 22867431 |
| vascular inflammations, Hypertensive (finding), Hypertension, CTCAE | Altered Intercellular Communication | Death-associated protein kinase 3 mediates vascular inflammation and development of hypertension in spontaneously hypertensive rats. | 22868392 |
| vascular inflammations, Hypertension, CTCAE | Altered Intercellular Communication | Pathogenesis of hypertension is modulated at least in part by vascular inflammation. | 22868392 |
| Inflammation, Hypertensive (finding), Hypertension, CTCAE, Hypertrophy | Altered Intercellular Communication | It is also suggested that DAPK3 mediates the development of hypertension in spontaneously hypertensive rats likely via ROS-dependent inflammation, hypertrophy, and hypercontractility. | 22868392 |
| Asthma | Altered Intercellular Communication | In elder patients with asthma, treatment with BUD/FM does not have any clinical disadvantage and may provide better efficacy in lung function, QOL, and possibly anti-inflammation compared with BUD plus Tulo treatment. | 22868522 |
| Inflammation, Primary malignant neoplasm, Diabetes Mellitus, Non-Insulin-Dependent, Cardiovascular Diseases | Altered Intercellular Communication | Inflammation has been implicated in the pathogenesis of cardiovascular disease, type 2 diabetes mellitus and cancer. | 22868815 |
| Inflammation | Altered Intercellular Communication | However, as this case shows, it may primarily involve the posterior uvea without anterior inflammation and may recur. | 22870033 |
| Renal Cell Carcinoma Pathway, Bipolar Disorder | Altered Intercellular Communication | Depressive symptoms and cortisol rhythmicity predict survival in patients with renal cell carcinoma: role of inflammatory signaling. | 22870317 |
| Amyotrophic Lateral Sclerosis, Inflammation | Altered Intercellular Communication | Animal and pathological studies suggest that inflammation may contribute to amyotrophic lateral sclerosis (ALS) pathology and that non-steroidal anti-inflammatory drugs (NSAIDs) might be protective. | 22871075 |
| ARCN1 gene, Bronchitis | Altered Intercellular Communication | Cysteinyl leukotriene 1 receptor expression associated with bronchial inflammation in severe exacerbations of COPD. | 22871757 |
| Inflammation | Altered Intercellular Communication | Despite elevated macrophage carbon load, tunnel mice showed no overt pulmonary or systemic inflammation, yet manifested reduced pulmonary thrombomudulin expression and elevated endothelial von Willebrand factor (VWF) expression in lung capillaries. | 22872007 |
| Pneumonitis | Altered Intercellular Communication | Hence, continuous traffic-related air pollution did not trigger overt lung inflammation, yet modified pulmonary endothelial cell function and enhanced platelet activity. | 22872007 |
| Inflammation, Cartilaginous metaplasia | Altered Intercellular Communication | Each PCL was histologically evaluated for inflammation, mucinous changes, chondroid metaplasia, cystic changes and orientation of collagen fibres. | 22872023 |
| Inflammation, Metabolic Diseases, Obesity | Altered Intercellular Communication | Obesity and metabolic disorders are linked to inflammation via gut microbiota and/or gut permeability. | 22872030 |
| Inflammation, Metabolic Syndrome X, ETV3 wt Allele | Altered Intercellular Communication | Gut-derived endotoxin triggers inflammation leading to metabolic syndrome (MetS) and contributing to oxidative stress. | 22872030 |
| Inflammation, Chronic Obstructive Airway Disease | Altered Intercellular Communication | Effects of active smoking on airway and systemic inflammation profiles in patients with chronic obstructive pulmonary disease. | 22874622 |
| ARCN1 gene, Inflammation, Chronic Obstructive Airway Disease | Altered Intercellular Communication | The markers that characterize local and systemic inflammation in chronic obstructive pulmonary disease (COPD) remain unclear, as do their correlations with smoking status and presence of disease. | 22874622 |
| ARCN1 gene, Inflammation, Smoking | Altered Intercellular Communication | Smoking is associated with higher systemic inflammation in patients with COPD. | 22874622 |
| Inflammation, Fibrosis Assessment | Altered Intercellular Communication | Histologic assessment revealed curability of ESD and inflammation and fibrosis around EIS site. | 22874708 |
| Inflammation, Edema, Ulcer | Altered Intercellular Communication | At day 0, both lower legs had significant oedema and circumferential venous-lymphatic ulcers, and the left leg showed signs of inflammation. | 22874827 |
| Inflammation, Edema, Ulcer | Altered Intercellular Communication | However, at day 8, inflammation, oedema and ulcer area had reduced. | 22874827 |
| Inflammation | Altered Intercellular Communication | We also show that oxPL stimulation increases expression of genes involved in macrophage infiltration, inflammation, and neovascularization in the eye. | 22875704 |
| methyldopa, Inflammation | Altered Intercellular Communication | Together, these findings suggest that CFH influences AMD risk by modulating oxidative stress, inflammation, and abnormal angiogenesis. | 22875704 |
| Myocarditis | Altered Intercellular Communication | This technique holds major promise as a potential method for assessing cellular myocardial inflammation and left ventricular remodelling, which may have a range of applications in patients with MI and other inflammatory cardiac conditions. | 22875883 |
| Inflammation, polychondritis, Systemic disease | Altered Intercellular Communication | Relapsing polychondritis is a rare multisystemic disease, which is characterized by recurrent inflammation of the cartilaginous structures. | 22876362 |
| Inflammation, Cytopenia, Lymphohistiocytosis, Hemophagocytic | Altered Intercellular Communication | Macrophage activation in hemophagocytic lymphohistiocytosis (HLH) leads to severe inflammation resulting in cytopenias and multi-organ dysfunction. | 22876565 |
| Inflammation, Heart failure, Atherosclerosis | Altered Intercellular Communication | Systemic inflammation has been linked to the development of heart failure in population studies including Multi-Ethnic Study of Atherosclerosis (MESA), but little evidence exists regarding potential mechanism of this relationship. | 22877812 |
| Liver carcinoma | Altered Intercellular Communication | Comparison of the prognostic value of inflammation-based prognostic scores in patients with hepatocellular carcinoma. | 22878374 |
| Refractory anemias, Bone Marrow Diseases, Atlanto-Axial joint, Neck Pain | Altered Intercellular Communication | Furthermore, surgery was often recommended to RA patients, because of the neck pain induced by RA-related inflammation of the atlanto-axial joint, regardless of any underlying myelopathy. | 22878378 |
| Intraocular inflammation, Macular retinal edema | Altered Intercellular Communication | The aim of the present study was to determine SST concentration in the vitreous fluid of patients with chronic uveitic macular oedema (CUMO) and quiescent intraocular inflammation. | 22878444 |
| Intraocular inflammation | Altered Intercellular Communication | Intravitreous SST is decreased in patients with CUMO and quiescent intraocular inflammation. | 22878444 |
| Immunology | Altered Intercellular Communication | Increasing evidence indicates that AF may be associated with immunologic inflammation responses, but it remains unclear whether activation of peripheral blood CD3(+) T-lymphocytes plays a role in the pathogenesis of AF. | 22878798 |
| Pneumonitis | Altered Intercellular Communication | Prevention of hyperoxia-mediated pulmonary inflammation in neonatal rats by caffeine. | 22878872 |
| ARCN1 gene, Inflammation | Altered Intercellular Communication | Airway epithelial cell apoptosis and inflammation in COPD, smokers and nonsmokers. | 22878876 |
| Inflammation, Leukemoid Reaction, Hyperalgesia, Allodynia | Altered Intercellular Communication | Parallel to this leukemoid reaction, allodynia and hyperalgesia developed in the absence of tissue inflammation. | 22878999 |
| Inflammation, Sarcoidosis | Altered Intercellular Communication | The purpose of this study was to assess the utility of (18)F-FDG PET/CT for detection of inflammation in granulomatous sites and management of patients with chronic sarcoidosis. | 22879080 |
| Inflammation, Retinal thickening | Altered Intercellular Communication | Severity of inflammation at baseline predicts the amount of retinal thickening in affected eyes. | 22879410 |
| Inflammation, Chronic Kidney Diseases | Altered Intercellular Communication | Among participants with CKD, inflammation significantly modified the associations of total cholesterol and LDL-C with IMT (P values for interaction, P<0.01 and P<0.001, respectively). | 22879436 |
| Alzheimers Disease | Altered Intercellular Communication | Importantly, methylation plays a central role for neurotransmitter generation like acetylcholine pointing to a crucial relevance of our findings for Alzheimer's disease. | 22879628 |
| Inflammation, Metabolic Syndrome X, ETV3 wt Allele | Altered Intercellular Communication | To determine whether the metabolic syndrome (MetS) or its components were more closely associated with disease states and inflammation in elderly adults. | 22880886 |
| Inflammation, Obesity, Abdominal, ETV3 wt Allele | Altered Intercellular Communication | The observation that MetS is associated with disease states and markers of circulating inflammation in the elderly is explained mainly by abdominal obesity and low HDL-C. Longitudinal data will further clarify these cross-sectional findings that MetS appears to be less than the sum of its parts in elderly adults. | 22880886 |
| Inflammation | Altered Intercellular Communication | PERIOD3 (PER3) polymorphisms have been associated with circadian disruption and changed secretion of cytokines involved in chronic inflammation. | 22881285 |
| ARCN1 gene, Chronic Obstructive Airway Disease, Bronchitis | Altered Intercellular Communication | Statin treatment may ameliorate viral infection-induced exacerbations of chronic obstructive pulmonary disease (COPD), which exhibit Th2-type bronchial inflammation. | 22881993 |
| ARCN1 gene, Inflammation | Altered Intercellular Communication | Thymic stromal lymphopoietin (TSLP), a hub cytokine switching on Th2 inflammation, is overproduced in viral and dsRNA-stimulated bronchial epithelial cells from COPD donors. | 22881993 |
| Inflammation | Altered Intercellular Communication | Oxidative stress induced by chronic inflammation could be a cause and antioxidants, including selenoproteins, may reduce the risk. | 22882569 |
| Inflammation | Altered Intercellular Communication | Oxidative stress produced by chronic inflammation could represent one of the causes, and antioxidants, including selenoproteins, may reduce the risk. | 22882569 |
| Liver Cirrhosis, Necrosis with inflammation | Altered Intercellular Communication | rtS106C, rtD134E/G/N/S and A-B interdomain mutations may be associated with necro-inflammation, immune response and cirrhosis development at ages older than 40. | 22882650 |
| Inflammation, myocardial injury | Altered Intercellular Communication | High-dose rosuvastatin loading before PCI significantly reduced periprocedural myocardial injury and periprocedural inflammation cytokines release and improved 3-month and 6-month clinical outcomes in female patients with NSTEACS who underwent PCI. | 22882843 |
| Inflammation | Altered Intercellular Communication | This was independent of age, sex, systemic inflammation and cytomegalovirus seropositivity. | 22882906 |
| Unknown (origin) (qualifier value), Inflammation | Altered Intercellular Communication | Bacterial biofilm does not seem to play a major role in the pathogenesis of idiopathic epistaxis in children (only positive in 7.1 % of cases by SEM) although a low-grade chronic inflammation is not infrequently present (37 % of cases detected by FISH). | 22885868 |
| Inflammation, With intensity | Altered Intercellular Communication | However, T2 hyperintensities in WM can also be caused by other mechanisms such as inflammation. | 22886015 |
| Alzheimers Disease", Inflammation, Data types - Address | Altered Intercellular Communication | Alzheimer's disease (AD) involves multiple pathological processes in the brain, including increased inflammation and oxidative damage, as well as the accumulation of amyloid-b (Ab) plaques. | 22886019 |
| Inflammation, Obesity, Abdominal, Hyperglycemia, Dyslipidemias, Diabetes Mellitus, Non-Insulin-Dependent | Altered Intercellular Communication | After adjustment for BMI, social-demographic, lifestyle and dietary factors and other TFAs, erythrocyte trans-18:1 was shown to be associated with a lower risk of type 2 diabetes (OR comparing extreme [first and fourth] quartiles 0.68, 95% CI 0.48, 0.97, p(trend) = 0.02), as well as 20-50% lower odds of central obesity, dyslipidaemia, hyperglycaemia, insulin resistance and chronic inflammation. | 22886370 |
| Tumor necrosis, Primary malignant neoplasm, Stomach Carcinoma, Inflammation | Altered Intercellular Communication | In tumor necrosis factor a-treated gastric cancer cells, HSP27 knockdown increased cell death and accumulation of the reactive oxygen species that link inflammation to cancer. | 22886594 |
| Gastrointestinal Hemorrhage, Intra-abdominal, Obstruction of biliary tree, Abdominal Pain, Intestinal Obstruction | Altered Intercellular Communication | Of 202 consultations, the diagnoses were wound problems (N = 39, 19%), bowel obstruction (N = 75, 37%), intra-abdominal inflammatory conditions (N = 36, 18%), abdominal pain of unclear etiology (N = 13, 6%), gastrointestinal hemorrhage (N = 15, 7%), malnutrition/feeding tube request (N = 14, 7%), and biliary obstruction (N = 10, 5%). | 22886727 |
| Inflammatory disease of mucous membrane | Altered Intercellular Communication | MMMS and FGMMS are equivalent in the amount of sinonasal mucosal inflammation and discomfort post endoscopic sinus surgery. | 22888489 |
| Inflammation, Pancreatitis Necrotizing | Altered Intercellular Communication | Results of the electron microscopic investigation of the pancreatic tissues biopsies, obtained intraoperatively from the demarcation inflammation focus, while operating 42 patients for an acute necrotic pancreatitis (ANP), were summarized. | 22888547 |
| deficiency aspects, Adenoma | Altered Intercellular Communication | Premenopausal women tended to have smaller adenomas than men, but neither adenoma size nor invasion was associated with multiple hormonal deficiency at presentation. | 22889015 |
| Inflammation | Altered Intercellular Communication | Systemic inflammation with inappropriate vasodilatation is observed in many patients with CS and may contribute to an excess mortality rate. | 22889197 |
| Inflammation, Metabolic Syndrome X, Obesity | Altered Intercellular Communication | Low-grade inflammation is linked to metabolic syndrome and obesity. | 22889406 |
| Inflammation, Fibrosis Assessment | Altered Intercellular Communication | Stat3 small interfering RNA suppressed indoxyl sulfate-induced expression of an inflammation marker gene (monocyte chemotactic protein-1), fibrosis marker genes (TGF-b(1), a-smooth muscle actin) and a subunit of nuclear factor-kB (p65), and attenuated a cellular senescence marker, senescence-associated b-galactosidase activity. | 22889746 |
| Stomach Carcinoma | Altered Intercellular Communication | Inflammation-based prognostic score predicts survival in patients with advanced gastric cancer receiving biweekly docetaxel and s-1 combination chemotherapy. | 22890015 |
| Inflammation, "Alzheimers Disease", Data types - Address | Altered Intercellular Communication | Microglia manage immunosurveillance and mediate inflammation, both suggested to be important in Alzheimer's disease (AD). | 22890100 |
| Inflammation, Extravasation, Injury of kidney | Altered Intercellular Communication | : Mice with one functional angiopoietin-2 allele developed milder kidney and lung injury, less tissue inflammation, and less vascular leakage compared to wild-type counterparts. | 22890252 |
| Inflammation, Myocardial | Altered Intercellular Communication | MicroRNA levels were not associated with myocardial damage or activation of inflammation. | 22890253 |
| Inflammation, Psoriasis | Altered Intercellular Communication | Psoriasis vulgaris (PV) is associated with low-grade systemic inflammation. | 22890310 |
| Pseudotumor, Neoplasms | Altered Intercellular Communication | In one case we found coexistence foreign body (shot) and tumor--inflammation pseudotumor of the orbita. | 22890536 |
| Inflammation | Altered Intercellular Communication | Regular physical activity is associated with lower markers of inflammation over 10 years of follow-up and thus may be important in preventing the proinflammatory state seen with aging. | 22891048 |
| Inflammation, Metabolic Syndrome X, Cardiovascular Diseases | Altered Intercellular Communication | There is accumulating evidence suggesting that inflammation is the bridging link between cardiovascular disease and metabolic syndrome. | 22891522 |
| Exanthema, Triggered by, Fever, CTCAE | Altered Intercellular Communication | Cryopyrin-associated periodic syndromes (CAPS) are characterized by apparently unprovoked attacks of fever, rashes, and musculoskeletal and sensorineural inflammation accompanied by high acute-phase reactants. | 22891689 |
| Nephritis, Lupus Erythematosus, Systemic | Altered Intercellular Communication | To assess whether urinary HMGB1 reflects renal inflammation we determined serum levels of HMGB1 simultaneously with its urinary levels in SLE patients with and without LN in comparison to healthy controls (HC). | 22892043 |
| Inflammation, Nephritis | Altered Intercellular Communication | These data suggest that urinary HMGB1 might reflect both local renal inflammation as well as systemic inflammation. | 22892043 |
| Inflammation, Cellulitis, Ulcer | Altered Intercellular Communication | Cellulitis is an acute inflammation of dermis and subcutaneous tissue, usually complicating wounds, ulcers, or dermatosis. | 22892081 |
| Vitreous inflammatory cells | Altered Intercellular Communication | Of 141 eyes, 115 (81.56%) showed vitreous inflammation. | 22892153 |
| Vitreous inflammatory cells | Altered Intercellular Communication | It was frequently bilateral with vitreous inflammation and characterized by multifocal lesions that were noncontiguous to the optic disc and showed serpiginoid spread. | 22892153 |
| Inflammation, Conductive hearing loss | Altered Intercellular Communication | Chronic obliterative otitis externa is a rare cause of conductive hearing loss, characterised by stenosis of the deep ear canal secondary to chronic inflammation. | 22892176 |
| Multiple Organ Failure, Inflammation, Leukocytosis, Fever, CTCAE, Specimen Source Codes - Abscess, Communicable Diseases, Single organ dysfunction, Hypotension, CTCAE, Systemic Inflammatory Response Syndrome, Empyema, Bacteremia, Cholangitis | Altered Intercellular Communication | Illness severity was classified as follows: none (no infection or inflammation), systemic inflammatory response syndrome (fever, leukocytosis), severe (abscess, cholangitis, empyema), or multi-organ dysfunction syndrome (bacteremia, hypotension, organ failure). | 22892201 |
| Hepatic inflammation | Altered Intercellular Communication | Follow-up liver biopsy after recovery showed improvement of hepatic inflammation and reduction of giant hepatocyte formation. | 22892492 |
| Mucous Membrane, Inflammation | Altered Intercellular Communication | and no differences in mucosal atrophy or the degree of chronic or acute inflammation were observed between groups 1, 2, and 3 (p>0.45). | 22892912 |
| Mucous Membrane, Inflammation, Metaplasia, Pouchitis | Altered Intercellular Communication | The degree of mucosal atrophy, the presence of colonic metaplasia, and the degree of acute or chronic inflammation do not appear to constitute risk factors for the development of pouchitis. | 22892912 |
| Inflammation, Intermittent Claudication | Altered Intercellular Communication | Impact of exercise training on inflammation and platelet activation in patients with intermittent claudication. | 22893497 |
| Neurogenic Inflammation, Sleep Apnea, Obstructive | Altered Intercellular Communication | Our results suggest that smoking may worsen OSAS through exacerbation of upper airway collapse at the level of the uvula, and that histological changes of the uvular mucosa correlated with smoking might be due to increased CGRP-related neurogenic inflammation. | 22893766 |
| Inflammation, Pathologic Neovascularization | Altered Intercellular Communication | CLSM was able to visualize features of cutaneous wound repair in epidermal and superficial dermal wounds, including aspects of inflammation, neovascularisation, and tissue remodelling in vivo. | 22894499 |
| Inflammation, Carcinogenesis | Altered Intercellular Communication | Chronic inflammation is a driving force for gastric carcinogenesis. | 22894650 |
| Granulomatous inflammation, Carcinoma | Altered Intercellular Communication | CBP were more sensitive than smears for both diagnoses of carcinoma (p = 0.01) and granulomatous inflammation (p = 0.048). | 22895864 |
| Granulomatous inflammation, Carcinoma, Breast cancer, lobular | Altered Intercellular Communication | Conversely, LBC was less sensitive than smears for granulomatous inflammation (p = 0.004), but the difference was not significant for carcinoma (p = 0.42). | 22895864 |
| Granulomatous inflammation, Carcinoma | Altered Intercellular Communication | CBP, as a complement to smears, increases diagnostic yield and sensitivity for both diagnoses of carcinoma and granulomatous inflammation. | 22895864 |
| Cholangitis | Altered Intercellular Communication | In conclusion, eosinophilic cholangitis is an uncommon, inflammatory condition that needs to be considered as a differential diagnosis for periampullary malignancies. | 22895905 |
| Inflammation, Arthritis | Altered Intercellular Communication | Because increased numbers of CD4+IL-17+ T cells are seen in both diseases, these observations imply that there are different mechanisms underlying chronic inflammation in these 2 forms of inflammatory arthritis. | 22896020 |
| Inflammation | Altered Intercellular Communication | Increased synovial inflammation and tendon degeneration at the time of surgery are correlated with the failed healing of rotator cuff tendons. | 22896627 |
| Communicable Diseases, Unknown (origin) (qualifier value), Vasculitis, CTCAE, Vasculitis, Hypersensitivity | Altered Intercellular Communication | Vasculitis in childhood is a result of a spectrum of causes ranging from idiopathic conditions with primary vessel inflammation to syndromes after exposure to recognized antigenic triggers, such as infectious agents and drugs causing hypersensitivity reactions. | 22897379 |
| Brucellosis, Infectious agent, Vasculitis, CTCAE, Vasculitis, Hypersensitivity, Henoch-Schoenlein Purpura | Altered Intercellular Communication | brucellosis, trigger agent, Henoch-Schonlein purpura, vasculitis, infectious agents, drug, hypersensitivity reactions, primary vessel inflammation. | 22897379 |
| Inflammation, Septic Shock | Altered Intercellular Communication | Viscoelastic and aggregometric point-of-care testing in patients with septic shock - cross-links between inflammation and haemostasis. | 22897591 |
| Sepsis | Altered Intercellular Communication | In the pathogenesis of sepsis, inflammation-induced changes in coagulation play a pivotal role. | 22897591 |
| Neurogenic Inflammation, Hypersensitivity | Altered Intercellular Communication | These findings suggest that visceral hypersensitivity in NERD patients is involved in neurogenic inflammation showing the increase in both substance P release and NK1R expression, which may be associated with the activation of TRPV1 and PAR2. | 22899239 |
| Inflammation, Biliary calculi | Altered Intercellular Communication | Among the factors contributing to the gallstones formation an important role belongs to the inflammation. | 22899412 |
| Sample Size Calculation, Damage, Vascular Diseases | Altered Intercellular Communication | Systemic sclerosis (SSc) is characterized by multisystem organ inflammation, endothelial wall damage, and vasculopathy. | 22899452 |
| Inflammation, Lyme Disease | Altered Intercellular Communication | Here we have analyzed pooled cerebrospinal fluid (CSF) allowing a deep view into the proteome for patients diagnosed with early disseminated Lyme disease and CSF inflammation. | 22900834 |
| Inflammatory Bowel Diseases, Inflammation | Altered Intercellular Communication | To reveal specific gene activation in nitric oxide (NO)-related inflammation we studied differential gene expression in inflammatory bowel disease (IBD). | 22900953 |
| Pain Distress Question, Inflammation, Fatigue | Altered Intercellular Communication | This suggests that in addition to treatments to reduce disease activity, strategies for alleviating fatigue in AS should focus on pain management techniques and actively treating inflammation. | 22901458 |
| Refractory anemias, Rheumatoid Arthritis | Altered Intercellular Communication | We aimed to investigate whether recognized hormonal predictors of rheumatoid arthritis (RA) also influence the severity of RA. | 22901865 |
| Airway structure, Exacerbation of asthma, Asthma | Altered Intercellular Communication | Some patients with severe asthma have recurrent asthma exacerbations associated with eosinophilic airway inflammation. | 22901886 |
| Airway structure | Altered Intercellular Communication | Early studies suggest that inhibition of eosinophilic airway inflammation with mepolizumab-a monoclonal antibody against interleukin 5-is associated with a reduced risk of exacerbations. | 22901886 |
| Exacerbation of asthma, Inflammation | Altered Intercellular Communication | Eligible patients were aged 12-74 years, had a history of recurrent severe asthma exacerbations, and had signs of eosinophilic inflammation. | 22901886 |
| Inflammation, Atherosclerosis | Altered Intercellular Communication | Regression analyses demonstrated that the increased levels of CD4(+)CD28(null) T cells were positively correlated to serum levels of C-reactive protein, suggesting systemic inflammation and atherosclerosis. | 22902395 |
| Inflammation, Stomach Carcinoma, Colorectal Carcinoma | Altered Intercellular Communication | The CRC thermograms were compared to those of healthy individuals and patients with gastric cancer and non-cancerous soft tissue inflammation. | 22903026 |
| Inflammation, Colorectal Carcinoma | Altered Intercellular Communication | The calorimetric profiles of blood plasma from CRC patients are found to be distinct from those of healthy individuals and those of patients with soft tissue, non-cancerous inflammation. | 22903026 |
| Delirium, Inflammation, Observation Method - Coagulation | Altered Intercellular Communication | Associations of markers of inflammation and coagulation with delirium during critical illness. | 22903241 |
| Delirium, Inflammation, Observation Method - Coagulation | Altered Intercellular Communication | To assess the associations between a priori-selected markers of inflammation and coagulation and delirium during critical illness. | 22903241 |
| Delirium, Inflammation | Altered Intercellular Communication | Two markers of inflammation and one of coagulation were significantly associated with delirium. | 22903241 |
| Delirium, Inflammation, Observation Method - Coagulation | Altered Intercellular Communication | These results suggest that specific aspects of inflammation and coagulation may play a role in the evolution of delirium during critical illness and that these markers should be examined in larger studies of ICU patients. | 22903241 |
| Meningitis | Altered Intercellular Communication | In the absence of meningeal inflammation, the CSF-to-serum albumin ratio (QAlbumin) was significantly higher in older patients than in younger ones. | 22903361 |
| Inflammation, FAM126A gene | Altered Intercellular Communication | Chronic inflammation contributes to the up-regulation of JNK activity in HCC. | 22903704 |
| Psoriasis, Dermatitis | Altered Intercellular Communication | Generalized pustular psoriasis (GPP) is a rare, potentially life threatening, and aggressive form of psoriasis, which is characterized by sudden onset with repeated episodic skin inflammation leading to pustule formation. | 22903787 |
| Cessation of life, Inflammation, Infectious Lung Disorder | Altered Intercellular Communication | Compared to ST228-I, ST22-IV had a significantly higher capacity to invade the A549 cells and a higher virulence in a murine model of acute lung infection causing severe inflammation and determining death in all the mice within 60 hours. | 22905220 |
| Inflammation, Damage | Altered Intercellular Communication | In individuals suffering from TA, arterial inflammation progresses to stenosis and/or occlusion, leading to organ damage and affecting survival. | 22905864 |
| ARCN1 gene, Inflammation | Altered Intercellular Communication | In COPD, serum biomarkers of inflammation and repair are distinctly associated with important clinical parameters and survival. | 22906131 |
| Inflammation | Altered Intercellular Communication | Alkaline phosphatase may serve as a biomarker and potential modulator of post-operative support and inflammation following cardiothoracic surgery in infants. | 22906145 |
| Inflammation, Metabolic Syndrome X, Atherosclerosis | Altered Intercellular Communication | Subjects with metabolic syndrome may have a closer relationship between inflammation and oxidative stress than subjects without metabolic syndrome, possibly reflecting their increased predisposition to atherosclerosis. | 22906280 |
| MS gene, Meningitis | Altered Intercellular Communication | Meningeal inflammation plays a role in the pathology of primary progressive multiple sclerosis. | 22907116 |
| Inflammation, MS gene | Altered Intercellular Communication | Inflammation in the leptomeninges has been identified as a key feature of secondary progressive multiple sclerosis and may contribute to the extensive cortical pathology that accompanies progressive disease. | 22907116 |
| MS gene, Meningitis | Altered Intercellular Communication | Our aim was to investigate the extent of perivascular and meningeal inflammation in primary progressive multiple sclerosis in order to understand their contribution to the pathogenetic mechanisms associated with cortical pathology. | 22907116 |
| Neurites, Meningitis | Altered Intercellular Communication | A variable extent of meningeal immune cell infiltration was detected and more extensive demyelination and neurite loss in the cortical grey matter was found in cases exhibiting an increased level of meningeal inflammation. | 22907116 |
| MS gene, Meningitis | Altered Intercellular Communication | Our data suggest that generalized diffuse meningeal inflammation and the associated inflammatory milieu in the subarachnoid compartment plays a role in the pathogenesis of cortical grey matter lesions and an increased rate of clinical progression in primary progressive multiple sclerosis. | 22907116 |
| Inflammation, RTEL1 gene | Altered Intercellular Communication | Serum lipid levels may serve as biomarkers of inflammation associated with NHL risk. | 22907421 |
| Inflammation, atherosclerotic, Chronic Kidney Diseases | Altered Intercellular Communication | Cytotoxic CD4+CD28 null T lymphocytes, systemic inflammation and atherosclerotic risk in patients with chronic kidney disease. | 22907478 |
| Inflammation, Perforation (observation) | Altered Intercellular Communication | A CT scan revealed what appeared to be a small bone impacted in a diverticulum with evidence of recent inflammation and a sealed perforation. | 22907849 |
| Inflammation, Chronic Kidney Diseases | Altered Intercellular Communication | The TAM receptors (tyro3, axl and mer) and their ligands (vitamin K-dependent proteins-Gas6 and Protein S) are crucial modulators of inflammation, which may be relevant in chronic kidney disease (CKD). | 22907951 |
| Inflammation, Thrombosis, Cerebral Atherosclerosis, Chronic Kidney Diseases | Altered Intercellular Communication | Gas6 and axl have multiple roles in mediating vascular atherosclerosis and injury, thrombosis and inflammation, yet nothing is known about the Gas6-axl pathway in humans with CKD. | 22907951 |
| Inflammation, Vascular Diseases | Altered Intercellular Communication | Given the prevalence of chronic inflammation and vascular disease in this population, we measured TAM ligands in patients with various levels of renal function. | 22907951 |
| Refractory Cytopenia of Childhood, Demographics Domain, Obesity | Altered Intercellular Communication | Our curdata suggest that insulin resistance may be inversely associated with RCC risk, independently of obesity, DM, lifestyle and hormonal confounding variables. | 22908063 |
| Inflammation, Benign neoplasm of prostate | Altered Intercellular Communication | Multicentre study on the efficacy and tolerability of an extract of Serenoa repens in patients with chronic benign prostate conditions associated with inflammation. | 22908779 |
| Inflammation, Depression, CTCAE | Altered Intercellular Communication | These findings support a unidirectional relationship in which depression is a risk-factor for inflammation. | 22910686 |
| Inflammation, Atherosclerosis | Altered Intercellular Communication | These results demonstrate that IL-27 might regulate the network of immunity and inflammation in the pathogenesis of atherosclerosis. | 22911112 |
| Inflammation, Liver Cirrhosis | Altered Intercellular Communication | In cirrhotic liver, most platelets were present in the sinusoidal space of the periportal area with inflammation, where HSCs expressing PDGF receptor-b were frequently observed. | 22911171 |
| Inflammation, Adult Non-Hodgkin Lymphoma | Altered Intercellular Communication | A two-stage evaluation of genetic variation in immune and inflammation genes with risk of non-Hodgkin lymphoma identifies new susceptibility locus in 6p21.3 region. | 22911334 |
| Inflammation, Lung Diseases, Obstructive | Altered Intercellular Communication | Heavy metal exposure may contribute to increased oxidative stress and inflammation in the lungs, resulting in tissue destruction manifesting clinically as obstructive lung disease (OLD). | 22911427 |
| Human immunodeficiency virus 2 (HIV-2), Inflammation | Altered Intercellular Communication | It is not known whether markers of inflammation such as high-sensitivity C-reactive protein (hsCRP), interleukin 6 (IL-6), and soluble CD14 (sCD14) may predict disease progression among HIV-2 patients. | 22911639 |
| Inflammation, Resolvin | Altered Intercellular Communication | Resolvins and protectins are families of local lipid mediators generated from the n-3 fatty acids eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA) during self-limited resolution of inflammation. | 22912397 |
| glycation, vascular inflammations | Altered Intercellular Communication | Positive association between serum level of glyceraldehyde-derived advanced glycation end products and vascular inflammation evaluated by [(18)F]fluorodeoxyglucose positron emission tomography. | 22912424 |
| Inflammation, Salmonella | Altered Intercellular Communication | Oral administration of a combination of select lactic acid bacteria strains to reduce the Salmonella invasion and inflammation of broiler chicks. | 22912447 |
| Meningitis | Altered Intercellular Communication | The three tests did not yield any better results in the subsets of children with moderate or severe meningeal inflammation, nor in relation to any of the causative pathogens. | 22914116 |
| Coughing, Inflammation, Fever, CTCAE | Altered Intercellular Communication | She presented with severe cough and fever, and bronchoscopy revealed inflammation of the trachea. | 22914966 |
| Inflammation, Ulcerative Colitis | Altered Intercellular Communication | Our case highlights the potential interest of (18)F-FDG PET for tracheal involvement of UC, allowing a non-invasive assessment of local inflammation. | 22914966 |
| Inflammation, "Alzheimers Disease", Data types - Address | Altered Intercellular Communication | There is significant evidence for a central role of inflammation in the development of Alzheimer disease (AD). | 22915243 |
| Inflammation, Intestines | Altered Intercellular Communication | Retrospectively, image quality (including motion artifact and bowel distention) and enteric inflammation were assessed. | 22915428 |
| Tumor necrosis, Inflammation | Altered Intercellular Communication | Tumour necrosis factor inhibition plus methotrexate is believed to inhibit radiographic progression independent of inflammation. | 22915617 |
| Refractory anemias, Rheumatoid Arthritis, Inflammation | Altered Intercellular Communication | We investigated whether rheumatoid arthritis (RA)-related autoantibodies were associated with systemic inflammation in a prospective cohort of first-degree relatives (FDRs) of RA probands, a population without RA but at increased risk for its future development. | 22915618 |
| Refractory anemias, Inflammation, Autoimmune Diseases | Altered Intercellular Communication | In first-degree relatives of patients with RA, RA-related autoimmunity is associated with inflammation, as evidenced by associations with multiple cytokines and chemokines. | 22915618 |
| Inflammation | Altered Intercellular Communication | To establish a relationship between visible third molars (M3s) and increased periodontal probing depths on teeth other than M3s and to examine the hypothesis that the presence of M3s and/or increased probing depths and local inflammation associated with M3s was associated with increased levels of serum inflammatory markers. | 22916700 |
| Inflammation | Altered Intercellular Communication | Retention of M3s in the presence of periodontal inflammation was associated with significant increases in the serum interleukin-6, soluble intracellular adhesion molecule-1, and C-reactive protein levels. | 22916700 |
| Inflammation, Sleep Disorders | Altered Intercellular Communication | Moderate exercise training may be a modality of non-pharmacological treatment for sleep disorders and inflammation. | 22917967 |
| Inflammation | Altered Intercellular Communication | To compare inflammation and lung function in swine workers after periods with and without respiratory protection during work. | 22918380 |
| Icterus, Inflammation, Neoplasms | Altered Intercellular Communication | To find a possible relationship between inflammation and CA19-9 tumor marker by analyzing data from patients with benign jaundice (BJ) and malignant jaundice (MJ). | 22919247 |
| Inflammation, Uveitis | Altered Intercellular Communication | After the second dose, there were 10 of them, while after the third dose of bevacizumab, there were 5 suffusions and 3 cases of inflammation of the anterior eye segment, anterior uveitis. | 22919878 |
| Arterial Stiffness, Inflammation, Refractory anemias | Altered Intercellular Communication | Arterial stiffness improved significantly in patients with early RA after effective control of inflammation. | 22920235 |
| glycation, Vascular Stiffness, Inflammation | Altered Intercellular Communication | Increase in sRAGE level was associated with a decrease in AIx, suggesting that sRAGE may play an important role in the ligand-soluble receptor for advanced glycation end product interaction propagated inflammation and vascular stiffness in these patients. | 22920235 |
| Dermatitis, Atopic, Inflammation, Psoriasis | Altered Intercellular Communication | Comparative transcriptomic analyses of atopic dermatitis and psoriasis reveal shared neutrophilic inflammation. | 22920495 |
| Lesion, Inflammation | Altered Intercellular Communication | Acute AD lesions are associated with T(H)2 and eosinophilic inflammation, whereas psoriatic lesions are associated with T(H)1/T(H)17 and neutrophilic inflammation. | 22920495 |
| Inflammation, allergic inflammation, Data types - Address, GDC Comorbidity Terminology | Altered Intercellular Communication | These data are evidence that neutrophilic inflammation is a feature of lesional AD pathology comorbid with allergic inflammation. | 22920495 |
| Inflammation, Vasculitis, CTCAE | Altered Intercellular Communication | Skin biopsies revealed lobular inflammation of the subcutaneous fat with vasculitis. | 22920648 |
| Inflammation, Bacterial Infections | Altered Intercellular Communication | We hypothesize that BCG-induced inflammation may eradicate bacterial infection. | 22921719 |
| Inflammation, Metaplasia, Necrosis | Altered Intercellular Communication | Necrotic salivary glands and inflammation were universal microscopic features; ductal metaplasia was present in only 1 case. | 22921832 |
| Pancreatic stone, Arteritis | Altered Intercellular Communication | Pancreatic stone protein/regenerating protein (PSP/reg) serum levels are supposed to be increased in bacterial inflammation. | 22922487 |
| Inflammation, "Alzheimers Disease", Data types - Address | Altered Intercellular Communication | There is growing consensus in the literature that inflammation plays a significant role in the pathophysiology of Alzheimer's disease (AD). | 22922667 |
| Inflammation, Data types - Address | Altered Intercellular Communication | The results of this study suggested that inflammation plays a role in the pathogenesis of AD. | 22922667 |
| Weight Gain, Inflammation, Cardiac dysfunction | Altered Intercellular Communication | Supplementary ultrafiltration may improve inflammation and cardiac dysfunction in patients with high interdialytic weight gain. | 22922813 |
| Inflammation, Malignant Neoplasms | Altered Intercellular Communication | Epidemiologic and experimental evidences support the concept that inflammation promotes the development and progression of cancers. | 22923190 |
| Renal Insufficiency, Hypertension, Renovascular, Right Ventricular Hypertrophy | Altered Intercellular Communication | Renovascular hypertension (RVH) is characterized by chronic inflammation of the stenotic kidney and progressive renal dysfunction. | 22923545 |
| Inflammation, Right Ventricular Hypertrophy, Ischemia | Altered Intercellular Communication | Chronic RVH is associated with elevated NGAL levels, likely due to ongoing kidney and systemic inflammation and ischemia. | 22923545 |
| Inflammation, Right Ventricular Hypertrophy | Altered Intercellular Communication | These findings may also imply the occurrence of the inflammation process in chronic RVH, which might contribute to the poorer outcomes of RVH compared with EH patients. | 22923545 |
| Acute Kidney Injury, CTCAE, Ischemia | Altered Intercellular Communication | Neutrophil gelatinase-associated lipocalin (NGAL), an acute phase protein induced in inflammatory conditions and ischemia, is a novel biomarker for acute kidney injury. | 22923545 |
| Alveolar damage, Disability Assessment for Dementia Questionnaire | Altered Intercellular Communication | Double immunohistochemistry of CMV antigen and cellular markers showed that epithelial tropism was associated with a diffuse alveolar damage (DAD) pattern (CMVp-DAD) while stromal tropism was associated with a predominantly interstitial inflammation/fibrosis (IIF) (CMVp-IIF) or a combination of DAD and IIF (CMVp-complex). | 22924849 |
| Inflammation, Atrial Fibrillation by ECG Finding | Altered Intercellular Communication | There is an accumulating body of evidence indicating a strong association between inflammation and the pathogenesis of atrial fibrillation (AF). | 22924939 |
| Asthma, Bronchial Hyperreactivity, Bronchitis | Altered Intercellular Communication | Bronchial inflammation and hyperresponsiveness in well controlled asthma. | 22925318 |
| Bronchitis | Altered Intercellular Communication | Little research has been devoted to the characteristics of bronchial inflammation in patients with stable, well controlled asthma. | 22925318 |
| Bronchitis | Altered Intercellular Communication | A total of 59 patients had persistent bronchial inflammation: 28 cases were considered eosinophilic, 28 neutrophilic, and 3 mixed. | 22925318 |
| Inflammation | Altered Intercellular Communication | The geometric mean (95% CI) of the methacholine PC20 was 1.74 mg/mL (1.04-2.93) in patients with eosinophilic inflammation and 4.14 mg/mL (2.5-6.84) in those with neutrophilic inflammation (P = 0.03). | 22925318 |
| Inflammation, Bronchial Hyperreactivity | Altered Intercellular Communication | Inflammation and bronchial hyperresponsiveness persist in most patients with well controlled asthma. | 22925318 |
| Inflammation, Asthma, Bronchitis | Altered Intercellular Communication | The study demonstrates that eosinophilic or neutrophilic inflammation persisted in most well controlled asthma patients despite the fact that their condition was controlled and therefore, measurement of bronchial inflammation seems essential to achieve proper asthma control. | 22925318 |
| allergic inflammation | Altered Intercellular Communication | Hematopoietic progenitor cells, especially those committed to the Eo/B lineage, are known to contribute to allergic inflammation. | 22925320 |
| Inflammation | Altered Intercellular Communication | In vitro and animal studies suggest that vitamin D may play a crucial role in immune activation and inflammation. | 22925537 |
| Heart Diseases, Inflammation | Altered Intercellular Communication | This system is expressed also in adipose tissue, which could thus be involved in cardiac disorders through modulation of metabolically triggered inflammation. | 22926037 |
| Depression, CTCAE | Altered Intercellular Communication | These prospective data support the role of fatty acid status in depression vulnerability and indicate a potential role for omega-3 fatty acids in the prevention of inflammation-induced depression. | 22926083 |
| Inflammation, Panophthalmitis | Altered Intercellular Communication | Panophthalmitis is an acute, purulent inflammation of the eyeball that involves all its structures and extends into the orbit. | 22926396 |
| Inflammation | Altered Intercellular Communication | A novel sinonasal endoscopy scoring system: the discharge, inflammation, and polyps/edema (DIP) score. | 22927217 |
| Mesenteric Panniculitis | Altered Intercellular Communication | First described in 1924, mesenteric panniculitis is a benign inflammatory condition of the bowel mesentery. | 22927274 |
| Neuroblastoma, Neoplasms | Altered Intercellular Communication | Metastatic neuroblastomas had higher infiltration of TAMs than locoregional tumors, and metastatic tumors diagnosed in patients at age >= 18 months had higher expression of inflammation-related genes than those in patients diagnosed at age < 18 months. | 22927533 |
| Communicable Diseases, Inflammation, Neoplasms | Altered Intercellular Communication | Definite diagnoses were categorized into four groups: inflammation (84.4%); infection (5.8%); tumor (6.5%); and nonspecific (3.2%). | 22928517 |
| Inflammation, Erythema Nodosum | Altered Intercellular Communication | The most common cause in the inflammation group was erythema nodosum. | 22928517 |
| Infection, Neoplasms | Altered Intercellular Communication | Various inflammatory conditions, infections, and tumors can present as tender cutaneous nodules of the legs. | 22928517 |
| Stomach Diseases | Altered Intercellular Communication | Reactive gastropathy is associated with inflammatory conditions throughout the gastrointestinal tract. | 22928604 |
| Inflammatory Bowel Diseases, Gastrointestinal inflammation | Altered Intercellular Communication | We show that genetic variation in FXR is associated with IBD, further emphasizing the link between bile acid signaling and intestinal inflammation. | 22929053 |
| Inflammation, Depression, CTCAE | Altered Intercellular Communication | IDO-induced alterations in serotonergic function may offer one biologic explanation to the well-established associations between inflammation and depression. | 22929065 |
| Communicable Diseases, Inflammation | Altered Intercellular Communication | No evidence of infection or inflammation was detected. | 22929158 |
| Communicable Diseases, Inflammation | Altered Intercellular Communication | A puzzling case of increased serum clozapine levels in a patient with inflammation and infection. | 22929408 |
| Communicable Diseases, Inflammation | Altered Intercellular Communication | First, a downregulation of CYP enzyme activities, which primarily seems to be mediated by interleukin-6, takes place during infection and inflammation. | 22929408 |
| Communicable Diseases, Inflammation | Altered Intercellular Communication | Second, the concentration of the acute phase protein a1-acid glycoprotein (AGP; orosomucoid) increases during infection and inflammation. | 22929408 |
| Inflammation | Altered Intercellular Communication | These observations suggest that lubricin is able to bind to PMN via an L-selectin-dependent and -independent manner and may play a role in PMN-mediated inflammation. | 22930755 |
| Renal Insufficiency, Inflammation, Cardiac dysfunction | Altered Intercellular Communication | To analyse the relationship between objectively measured daily walking duration and cardiovascular biomarkers of inflammation, cardiac dysfunction and renal impairment. | 22930799 |
| Inflammation, Degenerative disorder, HIV Infections | Altered Intercellular Communication | In addition to residual HIV infection, immune activation (leading to immunodeficiency) and some antiretrovirals might contribute to low-grade systemic inflammation that could drive tissue senescence and provoke degenerative and proliferative disorders. | 22930865 |
| Coronary microvascular dysfunction, Inflammation, Pentalogy of Cantrell, Lupus Erythematosus, Systemic | Altered Intercellular Communication | Subclinical coronary microvascular dysfunction can occur in SLE patients without traditional cardiovascular risk factors, probably associated with underlying inflammation and impairment of TAS. | 22931164 |
| Inflammation, Pancreatitis | Altered Intercellular Communication | Tumor-associated macrophages can be affected by cancer-related inflammation and pancreatitis and interact with important invasive behavior in a recurrent manner in pancreatic IDC. | 22931216 |
| Abnormal joint morphology, Coxitis | Altered Intercellular Communication | US examination found signs of hip joint abnormalities in 42% of the patients; US changes indicative of hip joint inflammation and damage were detected respectively in 24% and 32% of the cases. | 22931581 |
| Inflammation, Hypertension, CTCAE | Altered Intercellular Communication | [Structural and functional changes of the carotid artery and their relationship with subclinical inflammation in patients with H-type hypertension]. | 22931616 |
| Inflammation, Hypertension, CTCAE | Altered Intercellular Communication | To investigate the changes in the structure and function of the carotid artery and their relationship with subclinical inflammation in patients with H-type hypertension. | 22931616 |
| Inflammation, Hyperhomocysteinemia | Altered Intercellular Communication | These changes might be attributed to the synergism of subclinical inflammation and hyperhomocysteinemia, for which active intervention may prove beneficial. | 22931616 |
| Inflammation, Atherosclerosis | Altered Intercellular Communication | Transforming growth factor beta1 (TGFb1) is a multifunctional cytokine involved in inflammation and pathogenesis of atherosclerosis. | 22931704 |
| Inflammation, diabetic | Altered Intercellular Communication | We present an atypical clinical course of CST in a 61-year-old male diabetic patient caused by a distant focus of inflammation. | 22931741 |
| Airway structure, Chronic cough | Altered Intercellular Communication | The method and the preliminary data may be used for research, diagnosis and treatment of patients with chronic cough and airway inflammation. | 22932015 |
| Mucous Membrane, Inflammation | Altered Intercellular Communication | For histological improvement, gefarnate showed both effective in decreasing mucosal chronic inflammation (57.7% vs. 24.8%, P < 0.001, intension-to-treat) and active inflammation (36.4% vs. 23.1%, P < 0.05, intension-to-treat) than the control. | 22932084 |
| Inflammation, Chronic erosive gastritis | Altered Intercellular Communication | Gefarnate demonstrates an effective outcome on the mucosal inflammation in patients with chronic erosive gastritis. | 22932084 |
| Pulmonary Emphysema, Pneumonitis, Pulmonary Fibrosis | Altered Intercellular Communication | Characteristics of pulmonary inflammation in combined pulmonary fibrosis and emphysema. | 22932172 |
| Pneumonitis | Altered Intercellular Communication | However, the pulmonary inflammation characteristics of CPFE are not well known, and the differences between CPFE and the other two diseases with regards to pulmonary inflammation need to be explored. | 22932172 |
| Airway structure, Idiopathic Pulmonary Fibrosis, Pneumonitis | Altered Intercellular Communication | The pulmonary inflammation of CPFE group is more similar to IPF group, while the distal airway inflammation is more significant in CPFE and IPF groups than in EA group. | 22932172 |
| Pathology | Altered Intercellular Communication | Considering these low concentrations proved effective in vitro, translation of these data to human research on inflammation-related pathologies can be envisaged. | 22933405 |
| Orbital Pseudotumor | Altered Intercellular Communication | A 55-year-old woman with orbital inflammation. | 22933406 |
| Rheumatoid Arthritis, Inflammation | Altered Intercellular Communication | Elderly- versus younger-onset rheumatoid arthritis: higher levels of ultrasound-detected inflammation despite comparable clinical disease activity. | 22933417 |
| Inflammation, Rheumatoid Arthritis, ER-overload response | Altered Intercellular Communication | To compare ultrasound-verified joint inflammation between elderly-onset rheumatoid arthritis (EORA) and younger-onset rheumatoid arthritis (YORA) patients. | 22933417 |
| Inflammation | Altered Intercellular Communication | The sonographic pattern of joint involvement was similar in both groups, with active inflammation most commonly presenting at the wrists. | 22933417 |
| prostatitis | Altered Intercellular Communication | [Aggressiveness and extent of prostatic inflammation relates with serum PSA levels in type IV prostatitis]. | 22934516 |
| prostatitis | Altered Intercellular Communication | To investigate the relationship of the histopathologic grade and extent of prostatic inflammation with the level of serum PSA in patients with type IV prostatitis. | 22934516 |
| Aggressive behavior, prostatitis | Altered Intercellular Communication | We evaluated the relationship between prostatic inflammation and serum PSA levels based on the three-grade pathohistologic criteria for the extent, location and aggressiveness of prostatic inflammation. | 22934516 |
| Inflammation | Altered Intercellular Communication | Regarding the location of inflammation, 19 cases were grade I, 17 were grade II and 10 were grade II, with no significant differences in tPSA, fPSA and %fPSA among the three grades (P > 0.05). | 22934516 |
| Inflammation, Aggressive behavior | Altered Intercellular Communication | As for the aggressiveness of inflammation, 32 cases were grade I (tPSA: [8.37 +/- 4.07] microg/L; fPSA: [1.76 +/- 0.93] microg/L; PSAD: 0.14 +/- 0.11), 10 were grade II (tPSA: [13.30 +/- 5.69] microg/L; fPSA: [3.27 +/- 2.21] microg/L ; PSAD: 0.25 +/- 0.06) and 4 were grade III (tPSA: [21.05 +/- 7.58] microg/L; fPSA: [3.19 +/- 1.13] microg/L; PSAD: 0.42 +/- 0.19), with statistically significant differences among the three grades in the levels of tPSA (P = 0.002), fPSA (P = 0.024) and PSAD (P < 0.001). | 22934516 |
| Aggressive behavior, prostatitis | Altered Intercellular Communication | The aggressiveness and extent of prostatic inflammation in asymptomatic prostatitis patients are significantly correlated with the level of serum PSA, which may help pathologists to avoid unnecessary repeated biopsies for patients with high-grade prostatitis. | 22934516 |
| CLU protein, human, Ischemia, Inflammation | Altered Intercellular Communication | Chronic critical limb ischemia (CLI) is a severe condition of hypo-perfusion of lower limbs, which is associated with inflammation and a pro-coagulative state. | 22936457 |
| Inflammation, Calcinosis | Altered Intercellular Communication | In 4 cases calcification and in 19 cases inflammation was observed. | 22936554 |
| Exacerbation | Altered Intercellular Communication | PR3 activity was greater during exacerbations than in the stable state (p=0.037) and correlated with markers of neutrophilic inflammation. | 22936713 |
| Inflammation, Arthritis, Infectious | Altered Intercellular Communication | The joint fluid was inflammatory, with no crystals, and laboratory tests showed marked inflammation leading to antibiotic treatment for suspected septic arthritis. | 22937184 |
| Inflammation, Choroidal and Ciliary Body Melanoma pT1d TNM Finding v8 | Altered Intercellular Communication | Western blot analyses from T1D SAMP8 mice showed elevated amyloid precursor protein processing and protein glycation along with increased inflammation. | 22938075 |
| Inflammation, Phimosis | Altered Intercellular Communication | Non HPV related risk factors are lack of circumcision, phimosis, chronic inflammation, and smoking. | 22939906 |
| Inflammation, Neoplasms | Altered Intercellular Communication | Prognostic importance of markers for inflammation, angiogenesis and apoptosis in high grade glial tumors during temozolomide and radiotherapy. | 22940539 |
| Glioma, Inflammation, Carcinogenesis | Altered Intercellular Communication | Angiogenesis, inflammation and apoptosis have an important place in the carcinogenesis of high-grade gliomas (HGG). | 22940539 |
| Aphthous Stomatitis, Inflammation, Fever, CTCAE, Tonsillitis | Altered Intercellular Communication | A 10-year-old boy presented with periodic fever, exudative tonsillitis, oral aphthous ulcer, and cervical lymph node inflammation. | 22940910 |
| Inflammation, Brain Injuries | Altered Intercellular Communication | Inflammation following ischemic brain injury is correlated with adverse outcome. | 22942727 |
| Autoimmune Diseases, Inflammation, Thromboangiitis Obliterans | Altered Intercellular Communication | Activation of cytokines corroborate with development of inflammation and autoimmunity in thromboangiitis obliterans patients. | 22943198 |
| Vasculitis | Altered Intercellular Communication | The immune system seems to play a critical role in the aetiology of TAO; however, knowledge of the aspects involved in the progression of vascular tissue inflammation and, consequently, the evolution of this disease is still limited. | 22943198 |
| Malignant neoplasm of urinary bladder, Inflammation, Hematuria, CTCAE, Benign Prostatic Hyperplasia | Altered Intercellular Communication | Among them, 54 were diagnosed as bladder cancer, and the remaining 196, which consisted of healthy individuals and patients with hematuria, inflammation/infection, or benign prostate hyperplasia, were assigned to the control group. | 22944145 |
| Pain Distress Question, Inflammation, Edema, Lipodermatosclerosis, Pigmentation | Altered Intercellular Communication | The analysis of clinical severity scores (pain, edema, pigmentation, lipodermatosclerosis, and inflammation) revealed significant improvement when comparing pre- and post-treatment results. | 22944569 |
| Intradermal Route of Drug Administration | Altered Intercellular Communication | ID is more common in OW children; this may be due to adiposity-related inflammation reducing iron absorption. | 22945607 |
| Intraocular inflammation | Altered Intercellular Communication | Intraocular inflammation was inactive during the study period. | 22946454 |
| Intraocular inflammation, Low Vision | Altered Intercellular Communication | In well-controlled intraocular inflammation, increase in the ERM thickness does not lead to loss of vision in a 2-year FU period. | 22946454 |
| vascular inflammations, Hypertension, CTCAE | Altered Intercellular Communication | The hallmark of vascular inflammation is the recruitment of circulating leucocytes, primarily monocytes, macrophages and T lymphocytes, into the vascular wall; however, the link between monocyte/macrophage activation and hypertension has not been established as yet. | 22946776 |
| ARCN1 gene, Inflammation, Impaired | Altered Intercellular Communication | We studied heart rate variability (HRV) in COPD patients at rest and during the 6-minute Walk Test (6mWT) and the association with lung function impairment taking into account systemic inflammation. | 22946790 |
| ARCN1 gene, Inflammation, Impaired | Altered Intercellular Communication | At rest and during submaximal exercise, COPD patients with moderate and severe disease had an abnormal cardiac autonomic modulation which was related to both systemic inflammation and lung function impairment. | 22946790 |
| Atherosclerosis | Altered Intercellular Communication | Atherosclerosis is a chronic inflammatory condition that affects the arterial wall. | 22947906 |
| Inflammation, HIV-1 | Altered Intercellular Communication | Chronic inflammation from persistent immune activation could contribute to this poor response, resulting in HIV-1 disease progression and the development of some non-HIV-1 comorbidities. | 22948290 |
| Waldenstrom Macroglobulinemia, Pleurisy | Altered Intercellular Communication | Pleural biopsy performed during the decortication procedure revealed fibrinous pleuritis with lymphoplasmacytic inflammation including IgG4-positive plasma cells. | 22948582 |
| Inflammation, Duodenitis | Altered Intercellular Communication | Of the 93 patients with endoscopic features of duodenitis an increase in histological markers of inflammation was found in 75 (81%). | 22949941 |
| Inflammation, Musculoskeletal Pain, Arthritis, Infectious | Altered Intercellular Communication | In particular, minocycline-induced pigmentation of periarticular bone may be accelerated by inflammation due to rheumatic or pyogenic arthritis. | 22949948 |
| Neurodegenerative Disorders, "Alzheimers Disease", Data types - Address, Inflammation | Altered Intercellular Communication | Alzheimer disease (AD) is the most common neurodegenerative disease, and inflammation has been associated with the pathogenesis of AD. | 22950423 |
| Airway structure | Altered Intercellular Communication | The use of bronchodilators (BD), and inhaled corticosteroids (IC) have been suggested for the management of airway inflammation in CF. | 22950544 |
| Inflammation | Altered Intercellular Communication | Antiretroviral agents and chronic inflammation may adversely affect glycemic control. | 22951636 |
| Rhinosinusitis, Acute sinusitis | Altered Intercellular Communication | 10% of all cases with chronic inflammation of paranasal sinuses, were diagnosed with fungal rhinosinusitis. | 22952104 |
| Inflammation, Subarachnoid Hemorrhage, Cerebral Ischemia | Altered Intercellular Communication | Inflammation as a predictor for delayed cerebral ischemia after aneurysmal subarachnoid haemorrhage. | 22952245 |
| Inflammation, Compression neuropathy of ilioinguinal nerve | Altered Intercellular Communication | The results suggest that symptoms are related to tendon inflammation and ilioinguinal nerve compression, and can be abolished with pharmacological or radiofrequency treatment, without the need for surgery. | 22952407 |
| Inflammation, Metastatic hepatocellular carcinoma | Altered Intercellular Communication | Mesenchymal stem cells in inflammation microenvironment accelerates hepatocellular carcinoma metastasis by inducing epithelial-mesenchymal transition. | 22952657 |
| Inflammation, Tissue injury | Altered Intercellular Communication | In response to inflammation, mesenchymal stem cells (MSCs) are known to migrate to tissue injury sites to participate in immune modulation, tissue remodeling and wound healing. | 22952657 |
| Inflammation, Liver carcinoma, Neoplasm Metastasis, FAM126A gene | Altered Intercellular Communication | Here, we demonstrate that MSCs promote human hepatocellular carcinoma (HCC) metastasis under the influence of inflammation. | 22952657 |
| Pneumonitis | Altered Intercellular Communication | LPS-induced lung inflammation in marmoset monkeys - an acute model for anti-inflammatory drug testing. | 22952743 |
| Inflammation, Inflammatory disorder | Altered Intercellular Communication | In the current study, a tiered acute lipopolysaccharide (LPS)-induced inflammation model was established in marmoset monkeys (Callithrix jacchus) to reflect crucial features of inflammatory lung diseases. | 22952743 |
| Inflammation, Ischemia, Cessation of life, Damage, Candidal endocarditis | Altered Intercellular Communication | Candidal endocarditis complications include heart damage, inflammation, and emboli with resulting ischemia and tissue death. | 22953512 |
| Inflammation, Eczema | Altered Intercellular Communication | It is characterized by chronic inflammation, eczema, and increasing intestinal permeability. | 22955359 |
| Sjogrens Syndrome", Inflammation, Autoimmune Diseases | Altered Intercellular Communication | Sjogren syndrome is a common, chronic autoimmune disease that typically produces inflammation and poor function of the salivary and lacrimal glands. | 22955477 |
| Inflammation | Altered Intercellular Communication | Diagnostic tests were significant for marked systemic inflammation. | 22955481 |
| Inflammation, atherosclerotic | Altered Intercellular Communication | Macrophages in atherosclerotic plaques secrete YKL-40, a new biomarker of acute and chronic inflammation in patients with stable CAD. | 22955689 |
| Inflammation | Altered Intercellular Communication | We hypothesized that YKL-40 may be a specific marker reflecting the burden of localized inflammation in myocardium and a predictor in patients with STEMI. | 22955689 |
| Inflammation | Altered Intercellular Communication | Interleukin-17A plays a role in tissue inflammation by inducing release of proinflammatory and neutrophil-mobilizing cytokines. | 22955700 |
| Inflammation, Blood Clot, Aortic Aneurysm, Abdominal | Altered Intercellular Communication | Local inflammation is associated with aortic thrombus formation in abdominal aortic aneurysms. | 22955940 |
| Inflammation, Observation Method - Coagulation, Blood Clot | Altered Intercellular Communication | Interplay between coagulation and inflammation, characterised by leukocyte infiltration and cytokine production, has been implicated in AAA thrombus formation. | 22955940 |
| Inflammation | Altered Intercellular Communication | Increased stromal chronic inflammation correlated with longer disease-free interval (r(2) = 0.38). | 22956472 |
| Inflammation | Altered Intercellular Communication | Increased stromal chronic inflammation correlates with improved disease outcome. | 22956472 |
| Inflammation, Craniosynostosis | Altered Intercellular Communication | In CRS patients, expression of 471 genes, including inflammation and oxidative stress related genes was different from healthy controls. | 22957013 |
| Inflammation, Craniosynostosis, Anemia | Altered Intercellular Communication | In stable, treated CRS patients with mild anemia, monocyte transcriptomes were modestly altered, and indicated imprints of inflammation and oxidative stress. | 22957013 |
| Inflammation, Diabetes Mellitus | Altered Intercellular Communication | ESAM correlates with diabetes duration and control, inflammation and VEGF-A in patients with diabetes, but not in controls. | 22957687 |
| Inflammation, Prostate carcinoma, Neoplasms | Altered Intercellular Communication | Recent evidence suggests that CXCL16, a novel chemokine, is overexpressed in inflammation-associated tumors and mediates pro-tumorigenic effects of inflammation in prostate cancer. | 22958742 |
| vascular inflammations, Atherosclerosis | Altered Intercellular Communication | While viscosity correlated with parameters of vascular inflammation, it showed no relationship with the presence and severity of central atherosclerosis. | 22960302 |
| Inflammation | Altered Intercellular Communication | We hypothesized that markers of MT, soluble CD14 (sCD14) and lipopolysaccharide (LPS) binding protein (LBP), may be a source of chronic inflammation in older persons and be associated with poorer physical function. | 22960476 |
| Inflammation | Altered Intercellular Communication | In healthy older individuals, LBP, a surrogate marker of MT, is associated with worse physical function and inflammation. | 22960476 |
| Inflammation, BDI - Functional Impairment | Altered Intercellular Communication | Additional study is needed to determine whether MT is a marker for or a cause of inflammation and the associated functional impairments. | 22960476 |
| Inflammation, Werner Syndrome | Altered Intercellular Communication | Aging-associated inflammation in healthy Japanese individuals and patients with Werner syndrome. | 22960593 |
| Inflammation, Williams Syndrome | Altered Intercellular Communication | Both normal aging and WS were associated with minor inflammation that can be evaluated by serum hsCRP. | 22960593 |
| Werner Syndrome, Williams Syndrome | Altered Intercellular Communication | To study the inflammatory condition associated with normal human aging, highly sensitive CRP (hsCRP) was examined in the sera collected from 217 healthy Japanese individuals aged between 1 and 100years and 41 mutation-proven Japanese Werner syndrome (WS) patients. | 22960593 |
| Fibrous, Fibrosis Assessment, Perifolliculitis | Altered Intercellular Communication | The most common follicular-related changes were infundibular dilatation (87%) followed by perifollicular fibrosis (77%), perifollicular lymphocytic inflammation (68%), thinning of the follicular infundibulum (55%), and fibrous tracts (28%). | 22960818 |
| Inflammation | Altered Intercellular Communication | Since inflammation is known to modulate the microcirculation, we investigated the hypothesis that changes in the local perfusion might be one of the earliest signs of lesion development. | 22961546 |
| Inflammation, Coronary Arteriosclerosis, Myocardial Ischemia, Atherosclerosis | Altered Intercellular Communication | Systemic inflammation increases the risk of atherosclerosis and ischaemic heart disease (IHD). | 22961677 |
| Inflammatory Bowel Diseases, Inflammation, Myocardial Ischemia | Altered Intercellular Communication | The increased long-term risk of IHD in IBD may be related to chronic inflammation, and interventions reducing the inflammatory burden may attenuate this risk. | 22961677 |
| Presenile dementia, vascular inflammations, Ischemic stroke | Altered Intercellular Communication | Lipoprotein phospholipase-A2 (Lp-PLA2) is a circulating enzyme marker of vascular inflammation associated with risk of ischemic stroke and dementia. | 22961963 |
| Inflammation, Myocarditis, CTCAE 5.0, Infiltrative Tumor Margin | Altered Intercellular Communication | CMR imaging showed patterns of late gadolinium enhancement supportive of infiltrative disease or inflammation in 6 patients with EMB-proven definite (n=3) or borderline (n=3) myocarditis, but failed to do so in two other patients with borderline and two with resolving myocarditis. | 22963032 |
| Inflammation | Altered Intercellular Communication | Together with the early involvement of neutrophils and the destruction of the basal lamina, we suggest that the binding of autoantibodies to the nonhemidesmosomal lamina lucida may induce inflammation with neutrophils, resulting in blister formation. | 22963596 |
| vascular inflammations, Mucocutaneous Lymph Node Syndrome | Altered Intercellular Communication | The pathophysiology of Kawasaki syndrome presumably involves vascular inflammation, causing plasma leakage from systemic microvessels. | 22964445 |
| Inflammation, Idiopathic Inflammatory Myopathies | Altered Intercellular Communication | Toll-like receptors promote inflammation in idiopathic inflammatory myopathies. | 22964787 |
| Stomach Carcinoma | Altered Intercellular Communication | Comparison of two inflammation-based prognostic scores in patients with unresectable advanced gastric cancer. | 22964877 |
| Stomach Carcinoma, Atypical Glandular Cell | Altered Intercellular Communication | The objective of this study was to compare the usefulness of two inflammation-based prognostic scores, neutrophil to lymphocyte ratio (NLR) and modified Glasgow Prognostic Score (mGPS), assessed at diagnosis in stage IV advanced gastric cancer (AGC). | 22964877 |
| Inflammation, Refractory anemias, Degenerative polyarthritis, Rheumatoid Arthritis, Haiti, Hypertension, CTCAE | Altered Intercellular Communication | In this study, we compare the prevalence of arterial hypertension (HT) in rheumatoid arthritis (RA) and osteoarthritis (OA) patients, exposed to high- and low-grade chronic inflammation, respectively, to assess the possible association between chronic inflammation and HT. | 22965673 |
| Inflammation, Sinusitis | Altered Intercellular Communication | No disease was identified on 25.1% of pre-SCT CT scans, mild sinus inflammation was identified on 60.7% of scans, 11.3% had moderate inflammation, and 2.9% had severe inflammation. | 22965703 |
| Inflammation, Psoriasis, Chronic disease | Altered Intercellular Communication | Psoriasis is a chronic disease characterized by inflammation of the skin. | 22965812 |
| Inflammation, Coronary Arteriosclerosis | Altered Intercellular Communication | Both LAE and SAE, independent of traditional risk factors and inflammation, are associated with subclinical coronary atherosclerosis. | 22965846 |
| Inflammation, Aortic valve calcification, Chronic inflammatory disorder | Altered Intercellular Communication | Calcific aortic stenosis is a chronic inflammatory disease, and aortic valve interstitial cells (AVIC) play an important role in valvular inflammation. | 22965987 |
| Inflammation, Specimen Source Codes - Abscess | Altered Intercellular Communication | CT findings were: (i) nondiagnostic; (ii) moderate (peri-colic inflammation); and (iii) severe (abscess and/or extra-luminal gas and/or contrast). | 22967027 |
| Gastric mucosa, Gastritis | Altered Intercellular Communication | Increasing severity of gastric inflammation was observed in gastric mucosa infected with strains carrying RFLP-2, 3, 4, 5, and 6 (p = .037). | 22967117 |
| Intestinal metaplasia, Inflammation, Gland | Altered Intercellular Communication | All the scores for chronic inflammation, neutrophil activity, glandular atrophy, and intestinal metaplasia were significantly lower in H. pylori-positive Bangladeshis than in H. pylori-positive Japanese. | 22967124 |
| Inflammation, Thrombosis, myocardial injury | Altered Intercellular Communication | Myocardial injury was produced in CS-exposed marginal vitamin C-deficient guinea pigs as evidenced by release of cardiac Troponin-T and I in the serum, oxidative stress, inflammation, apoptosis, thrombosis and collagen deposition in the myocardium. | 22970172 |
| Inflammation, Carcinogenesis | Altered Intercellular Communication | We hypothesized that inflammation modulates carcinogenesis through senescence and DNA damage response (DDR). | 22970173 |
| Cataract, Inflammatory abnormality of the eye | Altered Intercellular Communication | Efficacy and safety of indomethacin 0.1% eye drops compared with ketorolac 0.5% eye drops in the management of ocular inflammation after cataract surgery. | 22970738 |
| Cataract, Inflammatory abnormality of the eye | Altered Intercellular Communication | To determine whether indomethacin 0.1% eye drops are at least as effective as ketorolac 0.5% eye drops in treating ocular inflammation following cataract surgery. | 22970738 |
| Cataract, Inflammatory abnormality of the eye | Altered Intercellular Communication | Indomethacin 0.1% was at least as effective as ketorolac 0.5% at Day 1 and more effective than ketorolac 0.5% at Day 7 in treating ocular inflammation after uncomplicated cataract surgery. | 22970738 |
| Inflammation, Malignant Neoplasms | Altered Intercellular Communication | The neutrophil-to-lymphocyte ratio (NLR), an inflammation marker, is prognostic in several cancers. | 22971522 |
| Inflammation, Malignant Neoplasms | Altered Intercellular Communication | Preoperative elevation of markers of systemic inflammation is associated with a poor outcome in several cancers. | 22972002 |
| PEA15 wt Allele | Altered Intercellular Communication | The corneal epithelial healing efficacy of PRP was compared with that of AS in patients with PED induced by post-infectious inflammation. | 22972393 |
| Synovitis | Altered Intercellular Communication | Disease-specific and inflammation-independent stromal alterations in spondylarthritis synovitis. | 22972410 |
| Refractory anemias, Inflammation, Rheumatoid Arthritis | Altered Intercellular Communication | The molecular processes driving the distinct patterns of synovial inflammation and tissue remodeling in spondylarthritis (SpA) as compared to rheumatoid arthritis (RA) remain largely unknown. | 22972410 |
| Inflammation | Altered Intercellular Communication | The fact that this stromal alteration appeared not to be downstream of local inflammation warrants further analysis of its functional role in the pathogenesis of the disease. | 22972410 |
| Inflammation, Depression, CTCAE | Altered Intercellular Communication | Is inflammation a new risk factor of depression in haemodialysis patients? | 22972567 |
| Inflammation, Depression, CTCAE, Bipolar Disorder | Altered Intercellular Communication | The aim of the study was to estimate the prevalence of depressive symptoms in haemodialyzed patients in Upper Silesia region of Poland and the possible role of inflammation in depression development. | 22972567 |
| Inflammation, Depression, CTCAE | Altered Intercellular Communication | (2) Catheter placement and inflammation seem to play an important role in the pathogenesis of depression in haemodialysis patients. | 22972567 |
| Acute inflammation | Altered Intercellular Communication | RAM-CLs were found in a subset of patients with MS who also have more active WM inflammation and a less favorable disease course. | 22972651 |
| Coinfection, Inflammation, Chronic sinusitis, Craniosynostosis | Altered Intercellular Communication | Persistent mucosal inflammation and microbial infection are characteristics of chronic rhinosinusitis (CRS). | 22972842 |
| Hepatitis | Altered Intercellular Communication | There was a close temporal correlation between IL-10 levels and fluctuations in viral load or liver inflammation. | 22972930 |
| Inflammation, Metabolic Syndrome X, Erectile dysfunction | Altered Intercellular Communication | Metabolic syndrome, hormone levels, and inflammation in patients with erectile dysfunction. | 22973171 |
| Inflammation, Metabolic Syndrome X | Altered Intercellular Communication | Chronic inflammation found in patients with ED might explain the association between ED and metabolic syndrome. | 22973171 |
| Inflammation, Metabolic Syndrome X, Erectile dysfunction | Altered Intercellular Communication | Metabolic syndrome, hormone levels, and inflammation in patients with erectile dysfunction. | 22973171 |
| Inflammation, Lichenoid | Altered Intercellular Communication | Comparing by response, normalization of stratum corneum and epidermis, orthohyperkeratosis, decrease in linearly arranged cells, the lichenoid/patchy lichenoid infiltration, the loss of inflammation were statistically significant in responders group. | 22973172 |
| Malaria, Falciparum, Inflammation, Plasmodium vivax | Altered Intercellular Communication | Although Plasmodium vivax usually causes a relatively benign disease, this parasite has been suggested to elicit more host inflammation per parasitized red blood cell than P. falciparum. | 22973442 |
| Malaria, Falciparum, Infection, Tissue damage | Altered Intercellular Communication | Controlling fast-multiplying P. falciparum blood stages requires a strong inflammatory response to prevent fulminant infections, while reducing inflammation-related tissue damage with early regulatory cytokine responses may be a more cost-effective strategy in infections with the less virulent P. vivax parasite. | 22973442 |
| Sepsis, Inflammation | Altered Intercellular Communication | Alterations of leptin in the course of inflammation and severe sepsis. | 22973876 |
| Interstitial Cystitis | Altered Intercellular Communication | Interstitial Cystitis (IC) is a chronic inflammatory condition of the bladder with unknown etiology. | 22974186 |
| Fibrosis Assessment, Myocarditis | Altered Intercellular Communication | Putative mediators of myocardial inflammation and fibrosis, including macrophage migration inhibitory factor (MIF), were also measured. | 22974800 |
| Inflammation, Atherosclerosis | Altered Intercellular Communication | Effects of p38 mitogen-activated protein kinase inhibition on vascular and systemic inflammation in patients with atherosclerosis. | 22974804 |
| Central Nervous System | Altered Intercellular Communication | Here, we have explored Purkinje cell fusion and heterokaryon formation in the human brain and the influence of central nervous system inflammation. | 22975392 |
| Inflammation, Calcinosis, Hyperplasia, Uterine Fibroids | Altered Intercellular Communication | Histological study showed elongation of the leaflets by myofibrotic and fibrotic hyperplasia without calcification and inflammation in the aortic valve. | 22975545 |
| Adrenal Gland Neoplasms, epinephrine, Neoplasms | Altered Intercellular Communication | Adrenal GN is a rare benign tumor, and its hormonal activity and imaging characteristics are occasionally very similar to those of other adrenal tumors. | 22975550 |
| Inflammation, Anti-Neutrophil Cytoplasmic Antibody-Associated Vasculitis, Traumatic injury | Altered Intercellular Communication | Serum proteins reflecting inflammation, injury and repair as biomarkers of disease activity in ANCA-associated vasculitis. | 22975753 |
| Inflammation, AAVS1 gene, Vasculitis, CTCAE | Altered Intercellular Communication | To identify circulating proteins that distinguish between active anti-neutrophil cytoplasmic antibody (ANCA)-associated vasculitis (AAV) and remission in a manner complementary to markers of systemic inflammation. | 22975753 |
| Inflammation, Microbleeds | Altered Intercellular Communication | When patients display asymmetrical subcortical white matter lesions with microbleeds on T(2)* weighted imaging, amyloid angiopathy-related inflammation should be considered. | 22975859 |
| Inflammation | Altered Intercellular Communication | As inflammation has been associated with other brain MRI findings, we investigated whether interleukin-6 and C-reactive protein were associated with the severity of dVRS in the eldery. | 22976070 |
| Inflammation | Altered Intercellular Communication | We found that elevated interleukin-6 levels were associated with higher severity of dVRS in basal ganglia, suggesting that inflammation might be associated with the burden of dVRS in the elderly. | 22976070 |
| Multiple polyps, Disorder of small intestine, Peutz-Jeghers Syndrome, Communicable Diseases, Diverticular Diseases, Celiac Disease, Systemic Scleroderma, Vasculitis, CTCAE, Malignant Neoplasms, Congenital duplication of intestine | Altered Intercellular Communication | In addition, MR enterography has an evolving though less well documented role to play in the evaluation of other small-bowel diseases, including various benign and malignant neoplasms arising in isolation or in polyposis syndromes such as Peutz-Jeghers, inflammatory conditions such as vasculitis and treatment-induced enteritis, infectious processes, celiac disease, diverticular disease, systemic sclerosis, and bowel duplication. | 22977028 |
| Thrombosis, Primary malignant neoplasm, Thrombophilia, Unknown (origin) (qualifier value), MVT Regimen, Hypertension, CTCAE, Myeloproliferative disease | Altered Intercellular Communication | Primary MVT is idiopathic, whereas secondary MVT can result from a variety of underlying diseases and risk factors, including primary hypercoagulable states or prothrombotic disorders, myeloproliferative neoplasms, cancer (most frequently of the pancreas or liver), diverse inflammatory conditions, recent surgery, portal hypertension, and miscellaneous causes such as oral contraceptives or pregnancy. | 22977032 |
| Inflammation, Primary malignant neoplasm, Telangiectasis | Altered Intercellular Communication | An unusual form of cutaneous infiltration involving a mammary region bearing a post-mastectomy surgical skin scar is herein described: interestingly, such a cutaneous cancer involvement could not be included in the above classification, because it merely consisted of red-purple areas dealing with small telangiectasias, without any sign of inflammation. | 22978058 |
| Mycobacterium Infections, Inflammatory abnormality of the eye | Altered Intercellular Communication | Two mechanisms can be proposed at the origin of ocular inflammation: a local immune response or a direct choroidal mycobacterial infection as demonstrated by vitreous cultures. | 22978181 |
| Inflammation, Endothelial dysfunction, ETV3 wt Allele | Altered Intercellular Communication | The current study found that individuals with MetS have a higher degree of endothelial dysfunction and inflammation compared with individuals with multiple CV risk factors and may therefore have an increased CV risk beyond the contributions of multiple traditional risk factors. | 22980166 |
| Inflammation, Primary malignant neoplasm, Infection | Altered Intercellular Communication | Immunosenescence, the progressive decline of adaptive immunity and chronic inflammation with ageing has been demonstrated to be the main factor responsible for infections, cancer and autoimmune conditions in the elderly. | 22980794 |
| Inflammation, Dislocations | Altered Intercellular Communication | Clinical parameters (age, total number of dislocations, and period since initial dislocation) were statistically independent from histopathologic parameters (inflammation, lipomatous changes, vascular proliferation, tissue fragmentation, and cellularity). | 22981356 |
| Communicable Diseases, Inflammation | Altered Intercellular Communication | In particular, aging of the immune system is characterized by progressive dysregulation of immune responses, resulting in increased susceptibility to infectious diseases, impaired vaccination efficacy and systemic low-grade chronic inflammation. | 22981370 |
| Inflammation, Deficient Food Intake | Altered Intercellular Communication | We hypothesize that epigenetic alterations and nutritional deficits associated with aging may lead to zinc transporter dysregulation, resulting in decreases in cellular zinc levels and enhanced inflammation with age. | 22981370 |
| Inflammation | Altered Intercellular Communication | Our data suggested that age-related epigenetic dysregulation in zinc transporter expression may influence cellular zinc levels and contribute to increased susceptibility to inflammation with age. | 22981370 |
| Arterial Stiffness, Inflammation, Vascular calcification | Altered Intercellular Communication | Pulse wave velocity (PWV) constitutes a valid index of arterial stiffness osteoprotegerin (OPG) and osteopontin (OPN) which are well-established vascular calcification inhibitors, highly correlated with inflammation, and cardiovascular events incidence. | 22982141 |
| Inflammation, Non-Small Cell Lung Carcinoma, Loss, Malignant Neoplasms | Altered Intercellular Communication | The tissue inhibitor of metalloproteinase 3 (TIMP-3) is essential for limiting inflammation; therefore, we expected that TIMP-3 loss might induce chronic inflammation, thereby promoting tumor malignancy as well as poor survival and relapse in patients with HPV-infected non-small cell lung cancer. | 22982189 |
| Inflammation, Anxiety, CTCAE 3.0, Depression, CTCAE, Coronary heart disease | Altered Intercellular Communication | Inflammation and symptoms of depression and anxiety in patients with acute coronary heart disease. | 22982340 |
| Inflammation, GDC AJCC Clinical Stage Terminology | Altered Intercellular Communication | ACS was associated with very high levels of inflammation, averaging 13.23x10(9)/l and 17.06 mg/l for white cell count and C-reactive protein respectively. | 22982340 |
| Inflammation, Depression, CTCAE, GDC AJCC Clinical Stage Terminology | Altered Intercellular Communication | The study provides some support for the hypothesis that the marked inflammation during ACS contributes to later depression in a subset of patients, but the evidence is not conclusive. | 22982340 |
| Inflammation, Transcription Initiation | Altered Intercellular Communication | The gene variants of the chemokine and chemokine receptor genes associated with inflammation may be involved in cancer initiation and progression. | 22982413 |
| Schizophrenia, Inflammation, Metabolic Syndrome X | Altered Intercellular Communication | The metabolic syndrome is highly prevalent in patients with schizophrenia, and is associated with a state of chronic, low-grade inflammation. | 22982547 |
| Schizophrenia, Inflammation | Altered Intercellular Communication | Schizophrenia is also associated with increased inflammation, including aberrant blood levels of pro-inflammatory cytokines and high-sensitivity C-reactive protein (hsCRP). | 22982547 |
| Schizophrenia, Inflammation, metabolic disturbance | Altered Intercellular Communication | Our findings suggest that measurement of total and differential WBC counts and hsCRP blood levels may be germane to the clinical care of patients with schizophrenia and related disorders, and support an association between inflammation and metabolic disturbance in these patients. | 22982547 |
| Presenile dementia, Inflammation | Altered Intercellular Communication | Studies that have investigated the association between markers of inflammation and risk of dementia are conflicting. | 22982688 |
| methyldopa, Inflammation | Altered Intercellular Communication | The impact of inflammation to the antioxidant defense parameters in AMD patients. | 22982945 |
| methyldopa, Inflammation | Altered Intercellular Communication | Oxidative stress and inflammation are postulated to be involved in the pathogenesis of the age-related macular degeneration (AMD) although the mechanism linking the oxidation and inflammation is still unknown. | 22982945 |
| Inflammation, Traumatic, Internal anal sphincter, Ischemia | Altered Intercellular Communication | Idiopathic chronic anal fissure is believed to be a consequence of a traumatic acute anodermal tear followed by recurrent inflammation and poor healing due to relative tissue ischaemia secondary to internal sphincter spasm. | 22983551 |
| ARCN1 gene, Inflammation, Chronic Obstructive Airway Disease | Altered Intercellular Communication | Patients with chronic obstructive pulmonary disease (COPD) have evidence of systemic inflammation that may be implicated in the development of comorbidities. | 22983959 |
| Alzheimers Disease", Data types - Address | Altered Intercellular Communication | Although dopamine deregulation has been observed in Alzheimer's disease (AD) patients, the dysfunction of this neurotransmitter has not been investigated in animal models of AD. | 22984283 |
| Inflammation, Obesity | Altered Intercellular Communication | To investigate whether the association of tCys with body fat extends to children at particular risk of obesity, and whether tCys is associated with insulin resistance and obesity-associated inflammation. | 22984471 |
| Inflammation, Rheumatoid Factor | Altered Intercellular Communication | The questionnaire items 'Red joints', 'Swollen joints', 'Warm joints' suggest differences in the level of inflammation between the groups although c-reactive protein (CRP) and rheumatoid factor (RHF) levels were equal. | 22984493 |
| Have Autoimmune or Inflammatory Condition | Altered Intercellular Communication | Previous studies implicated that IL23R and IL17 genes play an important role in autoimmune inflammation. | 22984500 |
| ARCN1 gene, Inflammation, Bronchitis | Altered Intercellular Communication | Long-term administration of low-dose inhaled corticosteroids decelerates the annual BMD loss in bronchitic patients, possibly by reducing both pulmonary and systemic chronic inflammation caused by COPD. | 22985270 |
| Sjogrens Syndrome", Inflammation, Autoimmune Disorder, CTCAE | Altered Intercellular Communication | The Sjogren's syndrome is a systemic autoimmune disorder characterized by chronic inflammation of the exocrine glands with extraglandular manifestations in up to 25% patients. | 22985924 |
| Benign Prostatic Hyperplasia, Inflammation | Altered Intercellular Communication | Pathogenic role of HIF-1a in prostate hyperplasia in the presence of chronic inflammation. | 22986049 |
| Inflammation, Large prostate | Altered Intercellular Communication | Although BPH is frequently accompanied by inflammation, it is unclear whether inflammation underlies prostate enlargement. | 22986049 |
| Large prostate | Altered Intercellular Communication | Therefore, we hypothesized that cytokines secreted from infiltrated macrophages under inflammatory conditions stimulate prostate enlargement by up-regulating HIF-1a. | 22986049 |
| Large prostate, prostatitis | Altered Intercellular Communication | Based on these results, we propose that HIF-1a mediates prostate enlargement under inflammatory conditions, and we suggest that HIF-1a be viewed as a promising target for blocking the transition from prostatitis to BPH. | 22986049 |
| Psoriatic Juvenile Idiopathic Arthritis, Inflammation, Malignant Neoplasms | Altered Intercellular Communication | We hypothesize that chronic inflammation is the driving force that enhances the risk of malignancy in psoriatic patients and suspect that psoriatic patients have higher risks for developing cancers that are most prevalent in the studied population. | 22986081 |
| Inflammation | Altered Intercellular Communication | During disease progression, inflammation and oxidative stress may well invoke humoral immunity against pathological aggregates of PD-associated a-synuclein. | 22986484 |
| Inflammation, Endothelial dysfunction, Complications of Diabetes Mellitus | Altered Intercellular Communication | YKL-40 is a marker of inflammation and endothelial dysfunction, both of which play important roles in the progression of diabetic complications. | 22986489 |
| Inflammation, Primary malignant neoplasm, Tumor Cell Invasion, Neoplasms | Altered Intercellular Communication | The pathways of neoplasia, invasion and inflammation are inextricably linked in cancer and aberrations in several regulatory pathways for these processes have been identified. | 22986533 |
| Inflammation, Cardiovascular Diseases | Altered Intercellular Communication | Inflammation is a critical participant in mediating all stages of cardiovascular disease. | 22986554 |
| Tracheitis | Altered Intercellular Communication | Short-term intubation in healthy patients resulted in significant tracheal inflammation. | 22986720 |
| Hyperglycemia | Altered Intercellular Communication | This association is absent in obese patients, who may be primed by obesity-induced inflammation to develop severe hyperglycemia even without experiencing the cytokine storm that is essential to GVHD pathogenesis. | 22987342 |
| Inflammation, Necrosis | Altered Intercellular Communication | Fibrinoid necrosis and intramural inflammation were observed in 8 cases. | 22987379 |
| Inflammation | Altered Intercellular Communication | Associations between arterial elasticity and markers of inflammation in healthy older women. | 22987795 |
| Inflammation, Optic Chiasms, Hypertrophy | Altered Intercellular Communication | MRI: diffuse enlargement of Optic Chiasm with inflammation of distal optic nerves bilateral. | 22989339 |
| Inflammation, Asthma | Altered Intercellular Communication | Airway responses and inflammation in subjects with asthma after four days of repeated high-single-dose allergen challenge. | 22989372 |
| Airway structure | Altered Intercellular Communication | Therefore, we designed a protocol for repetitive high-dose bronchial allergen challenges to generate clinical symptoms and airway inflammation. | 22989372 |
| Symptoms | Altered Intercellular Communication | Repeated high-dose bronchial allergen challenges resulted in severe asthma symptoms and marked Th-2-mediated allergic airway inflammation. | 22989372 |
| Fibrosis, Liver, Hepatitis, End Stage Liver Disease | Altered Intercellular Communication | Serum FSAP concentrations declined in patients with end-stage liver disease, and hepatic FSAP expression was decreased in patients with advanced liver fibrosis and liver inflammation. | 22989567 |
| Inflammation, Fibrosis Assessment, Injury of liver, Liver diseases | Altered Intercellular Communication | Lower FSAP expression is associated with enhanced liver fibrosis and inflammation in patients with chronic hepatic disorders and murine experimental liver injury. | 22989567 |
| Inflammation, Liver Cirrhosis, FAM126A gene | Altered Intercellular Communication | Severe inflammation in the background liver cirrhosis correlates with the development of poorly differentiated HCC in HCV-associated liver cirrhosis. | 22989817 |
| Inflammation, Liver carcinoma, Liver Cirrhosis, FAM126A gene | Altered Intercellular Communication | Whether severe inflammation in the background liver cirrhosis might correlate with the development of poorly differentiated human hepatocellular carcinoma (HCC) was studied in hepatitis C virus (HCV)-associated liver cirrhosis. | 22989817 |
| Inflammation | Altered Intercellular Communication | Inflammation in the background LC was evaluated by modified histology activity index (HAI). | 22989817 |
| Inflammation, Necrosis | Altered Intercellular Communication | To evaluate the inflammation, piece meal necrosis, intra lobular cellular degeneration and focal necrosis, portal cellular inflammation (each 0-4) were estimated. | 22989817 |
| Inflammation, Liver Cirrhosis, FAM126A gene | Altered Intercellular Communication | It is suggested that severe inflammation in the background cirrhosis accelerates the promotion in the HCC development from HCV-associated LC. | 22989817 |
| Airway structure, Wheezing | Altered Intercellular Communication | The role of bacteria, regulatory T (T(reg)) cells and their association with airway inflammation in preschool wheeze is largely unknown. | 22990010 |
| Airway structure, Wheezing | Altered Intercellular Communication | The analysis of EBC might serve as a helpful non-invasive tool to early assess airway inflammation in wheezing children. | 22990010 |
| Airway structure, Wheezing | Altered Intercellular Communication | The various elevated exhaled inflammatory markers indicate increased airway inflammation in wheezing preschool children. | 22990010 |
| Airway structure, Wheezing | Altered Intercellular Communication | In the presence of wheeze, we found no evidence for bacterial induced airway inflammation. | 22990010 |
| Inflammation, Swelling | Altered Intercellular Communication | It is characterized by inflammation of the "bronchial tree" that results in tissue swelling and excessive secretions of mucus into the bronchi, with progressive airflow limitation. | 22990540 |
| Inflammation | Altered Intercellular Communication | At points of contact with this material, destruction and severe polymorphic inflammation of the pulmonary parenchyma were noted. | 22990635 |
| Inflammation, Fibrosis Assessment | Altered Intercellular Communication | Liver biopsy showed lower inflammation [histological activity index (HAI) = 4] and fibrosis (F) (= 0) scores in genotype D than in genotypes A (HAI = 5, p < 0.001; F = 2, p = 0.008) or F (HAI = 5, p = 0.009; F = 2, p = 0.01). | 22990965 |
| Hyperglycemia, Inflammation | Altered Intercellular Communication | The main determinants of hyperglycaemia were an abnormal pre-pneumonia glucose metabolism and the intensity of the pneumonic inflammation. | 22991982 |
| Inflammation, Stomach Carcinoma, Neoplasms | Altered Intercellular Communication | PAR-1 has been involved in inflammation of the gastrointestinal tract, tumour cell growth and invasion of gastric carcinoma cells. | 22993310 |
| Inflammation, Tuberculosis, Unknown (origin) (qualifier value), Sarcoidosis, Orbital Myositis, Hyperthyroidism | Altered Intercellular Communication | Orbital myositis is inflammation of the extraocular muscles and can be either idiopathic, without a known etiology, or secondary to conditions such as tuberculosis, sarcoidosis, or hyperthyroidism. | 22993891 |
| Inflammation | Altered Intercellular Communication | Positive correlations were found between the markers of vascular endothelial activation and those of inflammation. | 22994085 |
| Sepsis, Inflammation, Atherosclerosis | Altered Intercellular Communication | Atherosclerosis is considered as a moderate systemic inflammation and we hypothesise that this chronic condition could have an impact on the outcome in sepsis. | 22994591 |
| Inflammation, physiopathological | Altered Intercellular Communication | We present a case of temporary cochlear nerve dysfunction due to endocochlear inflammation with subsequent recovery. | 22995199 |
| Inflammation | Altered Intercellular Communication | Continuous cochlear nerve stimulation at various levels may aid in function recovery after endocochlear inflammation. | 22995199 |
| Airway structure, Cystic Fibrosis | Altered Intercellular Communication | Although the increase in systemic inflammatory markers requires further evaluation, CXCR2 antagonism may be a useful approach for modulating airway inflammation in patients with cystic fibrosis. | 22995323 |
| Inflammation, Fibrosis Assessment, Edema, Lymphangiectasis | Altered Intercellular Communication | Microscopically, all cases exhibited stromal fibrosis and edema, multinucleated stromal cells, perivascular chronic inflammation, and lymphangiectasia. | 22995331 |
| Virus Diseases, Hepatitis, Chronic, FAM126A gene | Altered Intercellular Communication | The pathogenesis of HCC is closely associated with chronic liver inflammation fired by a variety of stimulates such as virus infection and metabolic stress. | 22996042 |
| Inflammation, Organ Dysfunction Scores, Bacterial Infections | Altered Intercellular Communication | During bacterial infection, activated polymorphonuclear leukocytes (PMNs) often cause inflammation and organ dysfunction in severely ill patients. | 22996209 |
| Inflammation | Altered Intercellular Communication | Inflammation is assumed to act in the pathogenesis of both diseases. | 22996633 |
| Inflammation, Cyclophosphamide/Vincristine/Dacarbazine Regimen, Cardiovascular Diseases | Altered Intercellular Communication | Growth differentiation factor 15 (GDF15), a stress-responsive cytokine produced in cardiovascular cells under conditions of inflammation and oxidative stress, is emerging as an important prognostic marker in individuals with and without existing cardiovascular disease (CVD). | 22997280 |
| Leprosy | Altered Intercellular Communication | Leprosy is characterised by a chronic granulomatous inflammation of the skin and peripheral nerves. | 22997696 |
| Lung Diseases, Obstructive | Altered Intercellular Communication | [Comparative characteristic of the hormonal profile in men with stable obstructive pulmonary disease and smokers]. | 22997716 |
| ARCN1 gene, Signs and Symptoms, Respiratory, Abnormal breathing, Chronic Obstructive Airway Disease, Bronchitis, Chronic | Altered Intercellular Communication | Comparative analysis of the hormonal profile was performed in 12 and 16 patients with mild and moderately severe chronic obstructive pulmonary disease (COPD) respectively, in 25 patients with chronic bronchitis, 13 smokers without respiratory symptoms and dysfunction of external respiration, and in healthy non-smokers. | 22997716 |
| Inflammation, antimony, Attack behavior, Arthritis, Calcium pyrophosphate deposition disease, Hypomagnesemia | Altered Intercellular Communication | Despite the rarity of this condition, it is important to know that hypomagnesaemia may be associated with calcium pyrophosphate crystal inflammatory arthritis (chondrocalcinosis) and that SBS patients may be prone to develop extreme hypomagnesaemia causing recurrent joint attacks without systemic inflammation. | 22998213 |
| Hashimoto Disease, Inflammation | Altered Intercellular Communication | Inflammation and increased myxovirus resistance protein A expression in thyroid tissue in the early stages of Hashimoto's thyroiditis. | 22998463 |
| Inflammation | Altered Intercellular Communication | Inflammation, expression of MxA, and the presence of the enteroviralcapsid protein (VP1) were characterized by immunohistochemistry. | 22998463 |
| Inflammation, Inflammatory disease of mucous membrane | Altered Intercellular Communication | In H. pylori-infected subjects, antral mucosal inflammation and activity improved significantly (P < 0.001) and stabilised after 3 years on esomeprazole while no change in inflammation was observed after LARS. | 22998687 |
| Inflammation, Peripheral visual field loss | Altered Intercellular Communication | Thus, the gradual relative loss of peripheral fat in aging humans may in part result from a defect in adipogenesis, which may be linked to inflammation and increased release of proinflammatory cytokines from fat tissue. | 22999012 |
| Inflammation | Altered Intercellular Communication | Unlike in many other inflammatory conditions, plasma suPAR levels do not reflect inflammation in AS. | 22999906 |
| Inflammation | Altered Intercellular Communication | Unlike in many other inflammatory conditions, plasma suPAR levels do not reflect inflammation in AS. | 22999906 |
| Osteoporosis | Altered Intercellular Communication | Interleukin-6 (IL-6) is produced by osteoblasts, and potently stimulates osteoclast activation playing a key role in normal bone resorption as well as in post-menopausal and inflammation-driven osteoporosis. | 22999910 |
| Osteoporosis | Altered Intercellular Communication | These data may provide further rationale for employing rosuvastatin to beneficially affect bone metabolism in post-menopausal women and possibly in inflammation-driven osteoporosis. | 22999910 |
| Inflammation, Venous Thromboembolism, vinyltriethoxysilane | Altered Intercellular Communication | Since venous thromboembolism (VTE) is associated with systemic inflammation and mortality as well, we have hypothesized that it is also associated with elevated vitamin B12 serum levels in elderly patients following major orthopedic surgery of the lower limb. | 23000313 |
| Inflammation, Fibrosis Assessment, Capsulitis, GDC AJCC Clinical Stage Terminology | Altered Intercellular Communication | Evidence suggests ACH may present in a similar progression through four stages as adhesive capsulitis of the shoulder (ACS) (from synovial inflammation to capsular fibrosis). | 23000348 |
| ARCN1 gene, Inflammation, Chronic Obstructive Airway Disease, lung growth, Asthma | Altered Intercellular Communication | Persistent chronic inflammation and impaired lung growth due to asthma in childhood may have long-term impact on pulmonary function and increase susceptibility to chronic obstructive pulmonary disease (COPD) in later life. | 23000796 |
| Nonspecific interstitial pneumonia, Pneumonia, Interstitial, HIV, Interstitial inflammation | Altered Intercellular Communication | The term nonspecific interstitial pneumonia (NSIP) was first used in relation to a pattern of lung interstitial inflammation seen in association with human immunodeficiency virus (HIV) infection. | 23001799 |
| Interstitial inflammation, Pneumonia, Fibrosis Assessment, Bronchiolitis Obliterans, Pneumonia, Interstitial | Altered Intercellular Communication | In 1994 NSIP was used to indicate a group of subacute or chronic interstitial pneumonias characterized morphologically by interstitial inflammation or fibrosis or both, with preservation of the lung architecture and the absence of typical findings for any of the other main categories of IIP (mainly usual interstitial pneumonia, desquamative interstitial pneumonia, and bronchiolitis obliterans organizing pneumonia). | 23001799 |
| Malignant mesothelioma, Inflammation, effusion | Altered Intercellular Communication | Forty three effusion cytology CBs of 25 confirmed malignant mesotheliomas were compared to CBs of 23 benign mesothelial effusions without inflammation and 13 reactive mesothelial proliferations associated with inflammation. | 23002041 |
| Inflammation, Peyronie Disease | Altered Intercellular Communication | Peironimev-Plus(r) in the treatment of chronic inflammation of tunica albuginea (Peyronie's disease). | 23004005 |
| vascular inflammations, Cardiac fibrosis, Cardiovascular Diseases | Altered Intercellular Communication | Mineralocorticoid Receptor (MR) activation is involved in blood pressure regulation and the pathogenesis of cardiovascular diseases, such as cardiac fibrosis, vascular inflammation and arterial aging. | 23006216 |
| Inflammation, Asthma | Altered Intercellular Communication | Exogenous PD1 conferred protection against eosinophilic inflammation in animals with experimental asthma, although its endogenous cellular source and functions in human airways are of interest. | 23006546 |
| Inflammation, Asthma | Altered Intercellular Communication | These observations are a first indication that activated human eosinophils represent a major source of PD1, which can act as a self-resolving machinery in eosinophilic inflammation, whereas the production of PD1 is impaired in patients with severe asthma. | 23006546 |
| Seizures, Inflammatory disease of mucous membrane | Altered Intercellular Communication | In addition, a positive FIT (>=100 ng/ml) predicted mucosal inflammation (Mayo 2 or 3) with sensitivity 0.87 and specificity 0.60, respectively. | 23007005 |
| Inflammation, Myocardial Infarction, Myocardial dysfunction | Altered Intercellular Communication | Compared with MICE, HIIE demonstrated a higher exercise adherence and was well tolerated in patients with HFREF, while still providing a high-level physiological stimulus and leaving indices of inflammation (CRP), myocardial dysfunction (BNP), and myocardial necrosis (cTnT) unaffected. | 23007142 |
| Stomach Carcinoma | Altered Intercellular Communication | Significance of the inflammation-based Glasgow prognostic score for short- and long-term outcomes after curative resection of gastric cancer. | 23007284 |
| Inflammation, Data types - Address | Altered Intercellular Communication | AR-GG27(r) showed a beneficial action associated with high compliance and tolerability in dermatological skin conditions characterized by inflammation and tissue oxidative stress in children, as PA with mild and moderate AD. | 23007324 |
| Airway structure, Asthma | Altered Intercellular Communication | Patients and their parents were educated about this disease (mechanism of asthma, airway inflammation, and necessity of asthma medication) and instructed to visit clinics regularly every 30 days. | 23007333 |
| Colitis | Altered Intercellular Communication | The expression levels of CCL20 mRNA and protein were significantly increased in the model group compared with those in the control group (P<0.01) and positively correlated with the severity of colonic inflammation. | 23008075 |
| Inflammation, Rosacea | Altered Intercellular Communication | Although inflammation appears to play a pathogenic role in rosacea, initiating factors are largely unknown. | 23009116 |
| Acute inflammation, Edema | Altered Intercellular Communication | Seven immunocompetent patients experienced acute anterior inflammation with graft oedema and pigmented keratic precipitates after penetrating keratoplasty. | 23009154 |
| Communicable Diseases, Inflammation, Amyloidosis | Altered Intercellular Communication | Infection (n = 10; 58.8%) was the most common cause of secondary amyloidosis during the 1990s, whereas chronic inflammation (n = 14; 48.2%) was the most common cause in 2000s. | 23009273 |
| Inappropriate ADH Syndrome | Altered Intercellular Communication | [Gait instability revealing a syndrome of inappropriate antidiuretic hormone secretion associated to pregabalin]. | 23010093 |
| Inflammation, Fibrosis Assessment | Altered Intercellular Communication | As the lesion matures, inflammation becomes less intense and the fibrosis progresses with an onion-skin type perivascular fibrosis. | 23010402 |
| Infarction, Inflammation, Contusions | Altered Intercellular Communication | Compared with controls, patients who were monitored had more pathologic changes related to invasive EEG monitoring (n = 171 [75.7%] vs n = 12 [21.8%]; P < .0001) including meningeal or parenchymal chronic inflammation (n = 128 [56.4%] vs n = 11 [20.4%]; P < .0001) and acute contusion and/or acute/subacute infarct (n = 110 [48.5%] vs n = 0; P < .0001). | 23010704 |
| Inflammation | Altered Intercellular Communication | The most common pathologic changes related to invasive monitoring were chronic inflammation and contusion/infarct. | 23010704 |
| palladium, Inflammation | Altered Intercellular Communication | It is important to establish the definition of persistent inflammation in the peritoneal cavity at the cessation of peritoneal dialysis (PD). | 23010754 |
| Inflammation, Fibrosis Assessment | Altered Intercellular Communication | It appears that PTX3 may be a new biomarker of peritoneal inflammation and progressive fibrosis. | 23010754 |
| Inflammation, Calcinosis | Altered Intercellular Communication | The process of calcification may be mediated by inflammation, which also may be related to multiple injections of air into the anterior chamber. | 23010776 |
| Inflammation, Arthritis, Hypersensitivity | Altered Intercellular Communication | Methylsulfonylmethane (MSM), which is one of the popular ingredients of so-called health foods in Japan, is expected to relieve inflammation in arthritis and allergies. | 23011466 |
| Primary immune deficiency disorder, Inflammation, Chronic granulomatous disease, Infection | Altered Intercellular Communication | Chronic Granulomatous Disease (CGD) is a rare primary immunodeficiency that predisposes to life-threatening infections and inflammation. | 23011479 |
| Inflammation, Sleep Apnea, Obstructive, Osage language | Altered Intercellular Communication | Untreated obstructive sleep apnoea (OSA) is characterised by elevated systemic and local oxidative stress and inflammation. | 23011770 |
| Inflammation, Sleep Apnea, Obstructive | Altered Intercellular Communication | Non-invasive measurement of metabolites and markers of inflammation in exhaled breath condensate (EBC) is of interest in the interpretation of systemic effects of severe obstructive sleep apnoea. | 23011770 |
| Inflammation, Osage language | Altered Intercellular Communication | This primarily represents a reduction of local inflammation and oxidative stress in the airways, but also indicates a positive effect on elevated oxidative stress in OSA. | 23011770 |
| Dystrophy, Inflammation | Altered Intercellular Communication | There were statistical significant differences between the types of dystrophy and inflammation (0.021), creatine kinase levels (p= 0.001), age (p=0.001), and gender (p < 0.001) of the patients. | 23011829 |
| Inflammation, Atherosclerosis | Altered Intercellular Communication | A-FABP (adipocyte fatty acid-binding protein), one of the most abundant proteins in adipocytes, plays a key role in obesity-related insulin resistance, inflammation and atherosclerosis in animals. | 23013043 |
| Granulomatous inflammation, Vegetation | Altered Intercellular Communication | The vegetations showed granulomatous inflammation but blood cultures and other biological specimen cultures were negative for any organisms. | 23013220 |
| Inflammation, Joint Tuberculosis, Degenerative polyarthritis, Rheumatoid Arthritis, Arthritis, Juvenile rheumatoid arthritis | Altered Intercellular Communication | Rice body formation is a nonspecific response to chronic synovial inflammation associated with tuberculous arthritis, rheumatoid arthritis, juvenile rheumatoid arthritis, seronegative inflammatory arthritis, and even osteoarthritis. | 23013846 |
| Inflammation, Diabetic Angiopathies | Altered Intercellular Communication | Inflammation is postulated to play a role in diabetogenesis and its further vascular complications. | 23014248 |
| Inflammation, Dyslipidemias | Altered Intercellular Communication | Low grade systemic inflammation, in association with dyslipidemia, plays a role in diabetogenesis and its complications. | 23014248 |
| Inflammation, Atherosclerosis | Altered Intercellular Communication | Both neoangiogenesis and inflammation contribute in atherosclerosis progression. | 23014482 |
| Inflammation, Malignant Neoplasms | Altered Intercellular Communication | Histological assessment found CD68 positive multinucleated giant cells in a highly cellular fibroblastic matrix surrounding bony lamellar structures, without signs of inflammation or malignancy. | 23015296 |
| Inflammation, Primary malignant neoplasm, Neoplasm Metastasis | Altered Intercellular Communication | E-selectin plays an important role in the process of inflammation and is also involved in the mechanism of cancer metastasis regulating the adhesion of circulating cancer cells to the blood vessels. | 23015400 |
| Inflammation, Albuminuria | Altered Intercellular Communication | Inflammation, oxidative stress, glomerular filtration rate, and albuminuria in elderly men: a cross-sectional study. | 23016573 |
| Renal Insufficiency, Inflammation | Altered Intercellular Communication | The role of inflammation and oxidative stress in mild renal impairment in the elderly is not well studied. | 23016573 |
| Inflammation, Renal function | Altered Intercellular Communication | Our data indicate that cytokine-mediated inflammation is involved in the early stages of impaired kidney function in the elderly, but that cyclooxygenase-mediated inflammation does not play a role at this stage. | 23016573 |
| Parkinson Disease, Lewy Bodies, palladium, Inflammation | Altered Intercellular Communication | Lewy pathology affects the gastrointestinal tract in Parkinson's disease (PD) and data from recent genetic studies suggest a link between PD and gut inflammation. | 23017648 |
| palladium, Gastrointestinal inflammation | Altered Intercellular Communication | We therefore undertook the present survey to investigate whether gastrointestinal inflammation occurs in PD patients. | 23017648 |
| palladium, Inflammation | Altered Intercellular Communication | Our findings provide evidence that enteric inflammation occurs in PD and further reinforce the role of peripheral inflammation in the initiation and/or the progression of the disease. | 23017648 |
| Celiac Disease, Inflammation, Intestinal Diseases | Altered Intercellular Communication | Celiac disease is a permanent enteropathy caused by the ingestion of gluten, which leads to an immunemediated inflammation of the small intestine mucosa. | 23018296 |
| Inflammation, Coronary Artery Disease | Altered Intercellular Communication | Inflammation and circulating endothelial progenitor cells in patients with coronary artery disease and residual platelet reactivity. | 23018312 |
| Inflammation | Altered Intercellular Communication | Low-level HIV viremia is associated with microbial translocation and inflammation. | 23018379 |
| Inflammation, Heart Failure, Systolic | Altered Intercellular Communication | Increased low-grade inflammation is associated with lack of functional response to carvedilol in patients with systolic heart failure. | 23018486 |
| Inflammation, Heart failure, Ventricular Dysfunction | Altered Intercellular Communication | Increased inflammatory activation observed only in heart failure patients not improving left-ventricular function after carvedilol may indicate that inflammation, either as a direct cause or as a consequence, is associated with progressive ventricular dysfunction. | 23018486 |
| Inflammation | Altered Intercellular Communication | This study showed decreased proportions of T(reg) in SIgAD patients, particularly in those with signs of chronic inflammation. | 23018812 |
| Hyperprolactinemia, Hypopituitarism | Altered Intercellular Communication | On hormonal examination, hypopituitarism with mild hyperprolactinemia was noted. | 23019401 |
| Inflammation, Uveitis | Altered Intercellular Communication | Typically, uveitis was bilateral (89%), chronic (89%), intermediate (89%), and associated with previous inflammation (29%), with synechiae (65%), and granulomatous (44%). | 23021230 |
| Inflammation, Myocardial | Altered Intercellular Communication | Biomarkers of myocardial damage and inflammation (ie, troponin I, creatine kinase-MB, myoglobin, C-reactive protein) rose in serum 2- to 812-fold after ASA (P < .01). | 23021916 |
| Inflammation, Primary malignant neoplasm | Altered Intercellular Communication | Experimental and epidemiological studies have revealed that chronic inflammation contributes to cancer progression and even predisposes to cellular transformation. | 23023232 |
| Inflammation | Altered Intercellular Communication | The activation of the above receptors results in the secretion of growth, chemotactic and angiogenic factors that contribute to chronic inflammation. | 23023232 |
| Inflammatory abnormality of the eye, Necrosis, Scleritis | Altered Intercellular Communication | After that, the introduction of an anti-tumor necrosis factor a drug (infliximab) completely resolved the severe scleritis and there was no recurrence of ocular inflammation. | 23023405 |
| Inflammation, Hemorrhage | Altered Intercellular Communication | anaesthetics, chemotherapy) or contrast media, bleeding, and inflammation. | 23023442 |
| Inflammation, Diabetes Mellitus, Non-Insulin-Dependent | Altered Intercellular Communication | Consumption of omega-3 fatty acid supplements is highly recommended to alleviate inflammation caused by type 2 diabetes mellitus. | 23023905 |
| Inflammation, Chronic Kidney Diseases | Altered Intercellular Communication | Increased risk of mortality in patients with CKD has been attributed to inflammation. | 23024164 |
| Inflammation, Albuminuria, Chronic Kidney Diseases | Altered Intercellular Communication | However, the association between kidney function, albuminuria, and biomarkers of inflammation has not been examined in a large cohort of CKD patients. | 23024164 |
| TNF protein, human, Inflammation | Altered Intercellular Communication | An inflammation score was established based on plasma levels of IL-1b, IL-6, TNF-a, hs-CRP, and fibrinogen. | 23024164 |
| Inflammation, Albuminuria | Altered Intercellular Communication | Biomarkers of inflammation were inversely associated with measures of kidney function and positively with albuminuria. | 23024164 |
| Communicable Diseases, Inflammation | Altered Intercellular Communication | Fluorodeoxyglucose positron emission tomography-computed tomography (18FDG PET-CT) has recently gained enthusiasm for its ability to detect infection and inflammation. | 23025952 |
| Cholecystitis | Altered Intercellular Communication | 18FDG PET-CT detected gallbladder inflammation in all but one patient with pathology-proven cholecystitis with a sensitivity and specificity of 0.90 and 1.00, respectively. | 23025952 |
| Hepatitis, Chronic, Disease | Altered Intercellular Communication | PMCs in both diseases had significantly increased TLR 9 expression perhaps implicating TLR9 expression in chronic liver inflammation. | 23026026 |
| Inflammation | Altered Intercellular Communication | Multilocular cystic structures accompanied by acute and chronic inflammation were observed in the remnant thymic tissues. | 23026930 |
| Multilocular Thymic Cyst, Malignant Neoplasms | Altered Intercellular Communication | Multilocular thymic cysts (MTCs) are considered to be acquired lesions associated with various inflammatory conditions and/or malignant tumors. | 23026930 |
| Inflammation, Neoplasms | Altered Intercellular Communication | (89)Sr accumulation seemed to be associated with bone turnover, in particular bone resorption, and vascularization due to inflammation or tumor growth. | 23027203 |
| Inflammation, Typhlitis, Epithelial, Edema, Hyperplasia | Altered Intercellular Communication | At 16 wpi, the ceca of H. bilis-infected Rag2(-/-) mice treated with control liposomes had significantly higher histopathological lesional scores (for cumulative typhlitis index, inflammation, edema, epithelial defects, and hyperplasia) and higher counts of F4/80(+) macrophages and MPO(+) neutrophils compared to H. bilis-infected Rag2(-/-) mice treated with clodronate liposomes. | 23027534 |
| Inflammation, Primary malignant neoplasm | Altered Intercellular Communication | These findings provide novel pathological evidence for inflammation and DDR in influencing non-metastatic progression of cancer in its microenvironment. | 23027622 |
| Inflammation | Altered Intercellular Communication | Associations may be modified by lifestyle factors that influence inflammation and oxidative stress. | 23027623 |
| Inflammation, Fibrosis Assessment | Altered Intercellular Communication | Only the rate of alveolar exudate/oedema in exudative phase cases (P = 0.003); those of alveolar histiocytic desquamation (P = 0.037), alveolar fibrosis (P = 0.017), chronic inflammation (P = 0.02), and alveolar fibrin (P = 0.001) in proliferative cases were significantly higher. | 23028252 |
| vascular inflammations, Rickettsia Infections | Altered Intercellular Communication | The pathophysiological hallmark of spotted fever group rickettsioses comprises vascular inflammation. | 23028464 |
| Inflammation, Rickettsia Infections | Altered Intercellular Communication | Based on the emerging importance of the wingless (Wnt) pathways in inflammation and vascular biology, we hypothesized that Dickkopf-1 (DKK-1), as a major modulator of Wnt signaling, could be involved in the pathogenesis in rickettsial infections. | 23028464 |
| Inflammation, Neoplasm Metastasis | Altered Intercellular Communication | Heparanase is an endo-b-glucuronidase that cleaves heparan sulfate side chains, leading to structural modifications that loosen the extracellular matrix barrier and associated with tumor metastasis, inflammation and angiogenesis. | 23028487 |
| Stomach Carcinoma | Altered Intercellular Communication | Our findings suggest that certain variants in the innate immunity and NHL-related genes affect the gastric cancer risk, perhaps by modulating infection-inflammation-immunity mechanisms that remain to be defined. | 23028900 |
| Inflammation, HIV-1 Infection Pathway | Altered Intercellular Communication | In progressive HIV-1 infection in horizontally infected adults, inflammation, T cell activation, and perturbed T cell differentiation lead to an "immune exhaustion", with decline in T cell effector functions. | 23029209 |
| Inflammation | Altered Intercellular Communication | A better understanding of the underlying molecular mechanisms causing systemic inflammation after CPB may aid in the development of new therapeutic approaches. | 23029213 |
| Inflammation, Atherosclerosis | Altered Intercellular Communication | T-cell phenotypes, apoptosis and inflammation in HIV+ patients on virologically effective cART with early atherosclerosis. | 23029393 |
| Inflammation | Altered Intercellular Communication | Chronic inflammation is a major contributing factor in the pathogenesis of many age-associated diseases. | 23029496 |
| Granulomatous inflammation, diabetic | Altered Intercellular Communication | We report a case of granulomatous inflammation in the prostate as a result of crypyococcus neoformans infection in a 70 year old immunocompetent patient, a non diabetic, which was diagnosed by transrectal ultrasound guided biopsy. | 23029729 |
| Inflammation, Vascular System Injuries | Altered Intercellular Communication | Osteoprotegerin (OPG) is known to regulate processes involved in vascular injury and inflammation. | 23030274 |
| Inflammation, Impaired T cell function | Altered Intercellular Communication | It was reported that anti-endothelial cell antibodies (AECAs) are associated with endothelial cell dysfunction and inflammation. | 23030505 |
| Salmonella enterica subsp. salamae, Granulomatosis, Cutaneous Small Vessel Vasculitis, Genus staphylococcus, Chronic necrotizing inflammation, Systemic Vasculitis | Altered Intercellular Communication | In granulomatosis with polyangiitis (GPA), a complex autoimmune small-vessel vasculitis frequently associated with chronic necrotizing inflammation of the nasal mucosa, elevated nasal Staphylococcus (S.) aureus carrier rates are a risk factor for relapse. | 23031229 |
| Refractory anemias, Inflammation, Rheumatoid Arthritis | Altered Intercellular Communication | Matrix metalloproteinases (MMPs) are implicated in the destruction of the joint and have been shown to be strongly associated with inflammation in rheumatoid arthritis (RA). | 23031278 |
| Inflammation, Leukocytosis, Brain Injuries | Altered Intercellular Communication | Leukocytosis at the time of ND correlates with poor functional outcomes and may represent a marker of greater cerebral damage through increased parenchymal inflammation. | 23031742 |
| Necrotizing granulomatous inflammation, Specimen Type - Fistula, Ulcer, Esophageal Stricture, Crohn Disease | Altered Intercellular Communication | The resected specimen and pathological results confirmed a deep linear ulcer, chronic and noncaseating granulomatous inflammation, as well as a circular stricture of the esophagus with fistula into the mediastinum due to isolated esophageal Crohn's disease. | 23031794 |
| Autoimmune Diseases | Altered Intercellular Communication | Those vesicles have recently been recognized as mediators of intercellular communication or as adjuvant in the pathogenesis of autoimmune diseases. | 23031801 |
| Granulomatous, Melanin pigmentation, Retroperitoneal fibrosis, Neoplasms | Altered Intercellular Communication | Retroperitoneal sclerosing PEComa with melanin pigmentation and granulomatous inflammation-a rare association within an uncommon tumor. | 23032844 |
| Granulomatous inflammation, Perivascular Epithelioid Cell Neoplasms, Neoplasms | Altered Intercellular Communication | Presence of melanin pigment and granulomatous inflammation in the present tumor constitute as novel histopathological findings in a sclerosing PEComa. | 23032844 |
| Glaucoma, CTCAE, Conjunctivitis | Altered Intercellular Communication | Conjunctival inflammation in patients under topical glaucoma treatment with indication to surgery. | 23033136 |
| Inflammation | Altered Intercellular Communication | Use of the retraction system failed in three out of five patients (60%) with intraoperative signs of chronic inflammation and in one out of 13 (7.1%) without such signs (p = 0.0441). | 23033957 |
| Extravasation of bile, Inflammation | Altered Intercellular Communication | Internal retraction enables a safe exposure of the Calot triangle avoiding bile spillage in cholecystectomies without intraoperative signs of inflammation. | 23033957 |
| Inflammation, Arteriosclerosis | Altered Intercellular Communication | Angiotensin receptor blockers (ARBs) are reported to provide direct protection to many organs by controlling inflammation and decreasing oxidant stress in patients without arteriosclerosis. | 23034088 |
| Inflammation, Pain Distress Question | Altered Intercellular Communication | We hypothesize that oxygen-ozone injections in paravertebral regions can induce a direct reduction of root inflammation with a corresponding reduction of pain. | 23034266 |
| Inflammation, Diabetes Mellitus, Non-Insulin-Dependent, Pathology, Obesity | Altered Intercellular Communication | Chronic adipose tissue inflammation is a hallmark of obesity, triggering the development of associated pathologies, particularly type 2 diabetes. | 23034965 |
| Myocarditis, Lupus Erythematosus | Altered Intercellular Communication | The diagnostic role of cardiac magnetic resonance imaging in detecting myocardial inflammation in systemic lupus erythematosus. | 23035042 |
| Viral myocarditis, Lupus Erythematosus, Myocarditis, Lupus Erythematosus, Systemic | Altered Intercellular Communication | The objective of this paper is to evaluate the diagnostic role of cardiac magnetic resonance imaging (CMR) in detecting myocardial inflammation in systemic lupus erythematosus (SLE) and its differentiation from viral myocarditis. | 23035042 |
| Inflammation, Sepsis, Tissue damage, Single organ dysfunction, Intravascular Route of Drug Administration, Cessation of life | Altered Intercellular Communication | Severe sepsis is characterised by intravascular or extravascular infection with microbial agents, systemic inflammation and microcirculatory dysfunction, leading to tissue damage, organ failure and death. | 23036162 |
| Sepsis, Inflammation, physiopathological | Altered Intercellular Communication | Administration of MAT.Ang-1 after the onset of sepsis protects the microcirculation from endotoxemia-induced vascular dysfunction through reducing inflammation but without pro-angiogenic actions, thus representing a novel, potential pharmacotherapeutic agent for the treatment of sepsis. | 23036162 |
| Inflammation | Altered Intercellular Communication | After first assessment, GCA was considered unlikely, since the sedimentation rate, as a marker for inflammation, was only slightly elevated. | 23036565 |
| Inflammation, Rheumatoid Arthritis | Altered Intercellular Communication | Dendritic cells provide a potential link between smoking and inflammation in rheumatoid arthritis. | 23036591 |
| Inflammation, Nasal Polyps, Neoplasms | Altered Intercellular Communication | Isolated REAH, which may mimic a neoplasm, appears to be a different clinical entity than the more common form encountered in association with nasal polyps and inflammation. | 23038055 |
| Degenerative polyarthritis, Inflammation | Altered Intercellular Communication | Inflammation was detected in over one-third of the participants, emphasizing the inflammatory component of OA and a possible important role for anti-inflammatory therapies in knee OA. | 23039323 |
| Inflammation | Altered Intercellular Communication | Our findings suggest that miR-21 may be a new biomarker of inflammation. | 23041385 |
| Intraocular inflammation | Altered Intercellular Communication | To investigate the posterior segment in cases of clinically evident intraocular inflammation for punctate reflections consistent with that expected to arise from inflammatory cells. | 23042101 |
| Intraocular inflammation | Altered Intercellular Communication | Eyes with intraocular inflammation had SD-OCT images of the vitreous containing punctate spots of a size consistent with that expected from inflammatory cells. | 23042101 |
| Inflammation | Altered Intercellular Communication | These results may imply a role for subclinical systemic inflammation and a beneficial effect of statins in the development of HPR in T2DM. | 23042313 |
| Inflammation, AMYOTROPHY, HEREDITARY NEURALGIC | Altered Intercellular Communication | Surgery and childbirth can trigger attacks of hereditary brachial plexus neuropathy (HBPN), and inflammation was suggested as a component of the pathogenesis. | 23042485 |
| Airway structure, Asthma | Altered Intercellular Communication | Clinical control of asthma associates with measures of airway inflammation. | 23042704 |
| Airway structure, Asthma | Altered Intercellular Communication | The Global Initiative for Asthma defined control by a composite measure of clinical findings and future risk but without using markers of airway inflammation, the hallmark of asthma. | 23042704 |
| Inflammation, Asthma | Altered Intercellular Communication | We investigated whether clinical asthma control reflects eosinophilic inflammation in a broad population. | 23042704 |
| Inflammation, Dental Plaque | Altered Intercellular Communication | At initial clinical examination, plaque accumulation, gingival inflammation and temporary restorations were noted. | 23043885 |
| Inflammation, Carcinoma of lung | Altered Intercellular Communication | Genetic variation in innate immunity and inflammation pathways associated with lung cancer risk. | 23044494 |
| Carcinoma of lung, Pneumonitis | Altered Intercellular Communication | Pulmonary inflammation may contribute to lung cancer etiology. | 23044494 |
| Inflammation, Carcinoma of lung | Altered Intercellular Communication | The current findings add to evidence implicating inflammation and immunity in lung cancer etiology. | 23044494 |
| Inflammation, Rheumatoid Arthritis | Altered Intercellular Communication | Ultrasound joint inflammation in rheumatoid arthritis in clinical remission: how many and which joints should be assessed? | 23044729 |
| Refractory anemias, Arthritis, MTTP wt Allele | Altered Intercellular Communication | US assessment of the wrist, MCP, ankle, and MTP joints can be highly sensitive for detecting residual B-mode and Doppler joint inflammation in RA patients. | 23044729 |
| Inflammation, Infiltration, Edema | Altered Intercellular Communication | In addition, we used fat saturation to distinguish T2 changes caused by edema and inflammation from fat infiltration in muscles. | 23044995 |
| Inflammation | Altered Intercellular Communication | Integrin-linked kinase (ILK) is an intracellular protein implicated in chronic inflammation and neoplastic transformation. | 23045294 |
| Inflammation, Virus Diseases, Diffuse Large B-Cell Lymphoma | Altered Intercellular Communication | Diffuse large B-cell lymphoma (DLBCL) is a heterogeneous disease with an association with inflammation and viral infections. | 23046110 |
| Paroxysmal nocturnal hemoglobinuria, Pancytopenia, eculizumab | Altered Intercellular Communication | Eculizumab is efficacious in patients with PNH, but responses can vary and may depend on underlying marrow failure, underlying inflammatory conditions and red cell clone size following treatment. | 23046169 |
| Inflammation, Periodontitis | Altered Intercellular Communication | Chronic periodontitis (CP) is a chronic inflammation associated with elevations of several inflammatory and cardiac markers. | 23046680 |
| Chronic Kidney Diseases | Altered Intercellular Communication | Malnutrition-inflammation score is associated with handgrip strength in nondialysis-dependent chronic kidney disease patients. | 23046737 |
| Inflammation | Altered Intercellular Communication | Chronic inflammation may not severely affect the CTN in pediatric patients, resulting in higher incidences of CTN regeneration and gustatory function recovery after severing the nerve, compared with those in adult patients. | 23047264 |
| Inflammation | Altered Intercellular Communication | We analyzed the hospital stay, the morbidity, the cost, and the severity of the inflammation and compared the open appendicectomy [OA (78)] with the LA (57) approach. | 23047396 |
| Inflammation, Neoplasms | Altered Intercellular Communication | Multivariate analysis including HMGB1, tumor, liver and inflammation markers revealed HMGB1 and CRP as independent prognostic parameters. | 23047645 |
| Inflammation, Atherosclerotic lesion | Altered Intercellular Communication | A reduction in collagen III content, particularly away from the atherosclerotic lesions, might be explained by the systemic vascular changes in patients with MI, and inflammation and immune responses could be potential causes of these systemic transformations. | 23049084 |
| Spermatic Cord Torsion, Pain Distress Question, Inflammation, Erythema, Swelling, Testicular Neoplasms | Altered Intercellular Communication | Even though the common causes of scrotal erythema with local swelling and pain are orchiepididimitis and testicular torsion, a careful examination followed by a precise ultrasound can reveal a developing testicular tumor, which was complicated by inflammation. | 23049638 |
| Diabetic Nephropathy, Fibrosis Assessment, Nephritis, diabetic | Altered Intercellular Communication | At the end of 3-month SFN treatment, the diabetic nephropathy, shown by renal inflammation, oxidative damage, fibrosis, and dysfunction, was significantly prevented along with an elevation of renal Nrf2 expression and transcription in diabetes/SFN group compared with diabetic group. | 23050040 |
| Inflammation, Atherosclerosis | Altered Intercellular Communication | Consequently, inflammation and atherosclerosis and its complications are in good correlation. | 23050404 |
| Communicable Diseases, Inflammation | Altered Intercellular Communication | Tb4 likely acts to repair and regenerate wounds by promoting cell migration and stem cell mobilization and differentiation, and by inhibiting inflammation, apoptosis, and infection. | 23050815 |
| Inflammation, Endocardium, Atrial Fibrillation by ECG Finding | Altered Intercellular Communication | Plasma proteins mediate thrombogenesis, inflammation, endocardial injury and structural remodelling in atrial fibrillation (AF). | 23052711 |
| Inflammation, Disorder of the optic nerve | Altered Intercellular Communication | Although two eyes showed LP(-) due to optic neuropathy, those eyes showed a remission in inflammation and an increase in IOP. | 23052719 |
| Communicable Diseases, Inflammation | Altered Intercellular Communication | Infection and inflammation were associated with development of hyperTG [C-reactive protein (CRP), r (2) = 0.19, p = 0.004]. | 23052949 |
| Gastrointestinal Stromal Tumors, Inflammation | Altered Intercellular Communication | Elevated blood NLR appears to represent systemic inflammation in patients with high-risk GIST. | 23054118 |
| Inflammation | Altered Intercellular Communication | Hypertrophic scar (HS) is a cutaneous fibrotic disorder characterized by persistent inflammation, excessive proliferation of fibroblasts, and abundant accumulation of extracellular matrix (ECM) proteins. | 23054143 |
| palladium, Inflammation | Altered Intercellular Communication | Here we review evidence that a-synuclein activates glia inducing inflammation and that Nrf2-directed phase-II antioxidant enzymes play an important role in PD. | 23054368 |
| palladium, Inflammation | Altered Intercellular Communication | This complex a-synuclein-directed glial response highlights the importance of protein misfolding, oxidative stress and inflammation in PD and represents a potential locus for the development of novel therapeutics focused on induction of the Nrf2-directed antioxidant pathway and inhibition of protein misfolding. | 23054368 |
| Eosinophilic disorder, Inflammation, Neurologic Deficits | Altered Intercellular Communication | Biological markers of inflammation or eosinophilia were present in 5/8 and a progressive motor deficit (7/8) is suggestive of the diagnosis. | 23054406 |
| Inflammation, Dental Plaque | Altered Intercellular Communication | Plaque destabilization results from the synergy between intraplaque angiogenesis and inflammation. | 23054554 |
| Inflammation, Traumatic injury | Altered Intercellular Communication | Trauma and severe inflammation may be good indications for en masse lobectomy. | 23054617 |
| Tumor necrosis, Inflammation, Psoriasis | Altered Intercellular Communication | The tumor necrosis factor alpha-induced protein 3 (TNFAIP3) gene functions in negative-feedback regulation of inflammation, and its single nucleotide polymorphism is associated with psoriasis. | 23054742 |
| Inflammation, Impaired cognition, Data types - Address | Altered Intercellular Communication | Decreased adiponectin may be a surrogate marker of the pathological process in AD, linking clinical comorbidities, inflammation and cognitive dysfunction. | 23055000 |
| Inflammation, Primary malignant neoplasm, Pathology | Altered Intercellular Communication | UNC5B is a membrane-bound receptor of the neural guidance factor netrin-1 family, with important roles in angiogenesis, neurogenesis, embryonic development, cancer, inflammation and various pathologies. | 23055195 |
| Inflammation | Altered Intercellular Communication | Heme oxygenase-1 (HO-1), a rate-limiting enzyme in heme catabolism, is known to play a role in the protection of cells against oxidative stress, inflammation, anomalous proliferation and apoptosis. | 23055342 |
| ARCN1 gene, Inflammation, Chronic Obstructive Airway Disease | Altered Intercellular Communication | The aim of this study is to determine the role of aB-crystallin in chronic obstructive pulmonary disease (COPD) pathogenesis and inflammation. | 23055712 |
| Chronic Obstructive Airway Disease, Acute inflammation | Altered Intercellular Communication | The same could be observed comparing the group of patients with acute inflammation and non-COPD healthy smokers (P = 0.007). | 23055712 |
| ARCN1 gene, Inflammation | Altered Intercellular Communication | There was no statistically significant difference between patients with mild/moderate inflammation and those with severe COPD. | 23055712 |
| Inflammation, Neoplasms | Altered Intercellular Communication | Tumor endothelial inflammation predicts clinical outcome in diverse human cancers. | 23056240 |
| Disease, Inflammation, Malignant Neoplasms, Neoplasms | Altered Intercellular Communication | Vascular endothelial cells contribute to the pathogenesis of numerous human diseases by actively regulating the stromal inflammatory response; however, little is known regarding the role of endothelial inflammation in the growth of human tumors and its influence on the prognosis of human cancers. | 23056240 |
| Tumor necrosis, Inflammation | Altered Intercellular Communication | Using an experimental model of tumor necrosis factor-alpha (TNF-a)-mediated inflammation, we characterized inflammatory gene expression in immunopurified tumor-associated endothelial cells. | 23056240 |
| Neoplasms, Chronic inflammation, Disease | Altered Intercellular Communication | We report that expression of experimentally derived tumor endothelial genes distinguished pathologic tissue specimens from normal controls in several human diseases associated with chronic inflammation. | 23056240 |
| Inflammation, Primary malignant neoplasm | Altered Intercellular Communication | This study provides the first prognostic cancer gene signature derived from an experimental model of tumor-associated endothelial inflammation. | 23056240 |
| Airway structure | Altered Intercellular Communication | Airway inflammation defined by sputum neutrophils showed only a moderate repeatability. | 23056262 |
| Epilepsy | Altered Intercellular Communication | Epileptic men may experience hormonal changes that may alter semen quality and sexual function. | 23057419 |
| Inflammation, Diabetes Mellitus, Non-Insulin-Dependent | Altered Intercellular Communication | Elevated markers of systemic inflammation are associated with impaired glucose tolerance and type 2 diabetes mellitus. | 23057577 |
| Biliary calculi, Biliary Tract Cancer | Altered Intercellular Communication | Genetic variants in inflammation-related genes have been associated with biliary stones and biliary tract cancers in previous studies. | 23057767 |
| Inflammation, Liver and Intrahepatic Biliary Tract Carcinoma, Biliary calculi | Altered Intercellular Communication | These findings provide additional support for the role of inflammation in biliary stones and biliary tract cancer risk and need further validation. | 23057767 |
| Chronic sinusitis, Nasal obstruction present finding, Inflammatory disease of mucous membrane | Altered Intercellular Communication | Predicting which chronic rhinosinusitis patients have nasal obstruction due to reversible mucosal inflammation could prevent unnecessary surgery. | 23057871 |
| Inflammation, Atherosclerosis | Altered Intercellular Communication | Adipocyte fatty acid-binding protein (A-FABP) is expressed in adipocytes, macrophages and microvascular endothelial cells, and it plays a central role in inflammation, atherosclerosis and metabolic responses. | 23057990 |
| Chronic Kidney Diseases | Altered Intercellular Communication | Advanced chronic kidney disease is associated with perturbations in adipose-derived hormones (leptin, adiponectin, and resistin). | 23058473 |
| ARCN1 gene, Inflammation, Respiratory Failure | Altered Intercellular Communication | COPD patients who incur higher healthcare resource utilisation show reduced physical activity, increased respiratory failure and increased systemic inflammation. | 23058483 |
| Inflammation, Dental Plaque | Altered Intercellular Communication | Sex-related differences in carotid plaque features and inflammation. | 23058720 |
| Inflammation, Dental Plaque | Altered Intercellular Communication | Histologic analysis was performed, as well as measurements of plaque composition and inflammation. | 23058720 |
| Inflammation, Dental Plaque | Altered Intercellular Communication | Plaque inflammation analysis showed a lower concentration of inflammatory and, in particular, of macrophage foam cells in the plaque cap of women (both P < .05). | 23058720 |
| Inflammation, Myositis | Altered Intercellular Communication | Satellite cells and regenerating fibers were significantly increased in s-IBM similar to other inflammatory myopathies and correlated with the intensity of inflammation (R>0.428). | 23058947 |
| Inflammation | Altered Intercellular Communication | Our findings indicate profound myo-endothelial remodeling of s-IBM muscle concomitant to inflammation. | 23058947 |
| Cancer Pain | Altered Intercellular Communication | A panel of 168 inflammation-related and prostate cancer-related genes was assessed with optimised quantitative PCR to assess biomarkers predictive of survival. | 23059047 |
| Inflammation, Neoplasms | Altered Intercellular Communication | NO metabolites, and conventional inflammation and tumor markers were determined. | 23059408 |
| Carcinogenesis, Colorectal Carcinoma | Altered Intercellular Communication | Inflammation contributes to the pathogenesis of colorectal cancer (CRC), and cytokine levels are altered during colorectal carcinogenesis. | 23059742 |
| Stomach Carcinoma | Altered Intercellular Communication | Inflammation-based prognostic score as a predictor of postoperative gastric cancer recurrence. | 23060589 |
| Neoplasm Metastasis, Neoplasms | Altered Intercellular Communication | The inflammation-based prognostic score was significantly associated with tumor size and lymph node metastasis. | 23060589 |
| ARCN1 gene, Inflammation, Chronic Obstructive Airway Disease | Altered Intercellular Communication | Chronic obstructive pulmonary disease (COPD) is characterized by persistent airflow limitation; from a pathophysiological point of view it involves many components, including mucus hypersecretion, oxidative stress and inflammation. | 23061828 |
| Inflammation, Primary malignant neoplasm | Altered Intercellular Communication | It has been hypothesized that flavonoids in foods and beverages may reduce cancer risk through antioxidation, inhibition of inflammation, and other antimutagenic and antiproliferative properties. | 23061904 |
| Inflammation | Altered Intercellular Communication | IgG4-positive ascending aortic wall was frequent in our study cohort (13%) and revealed aortic inflammation associated with dilatation. | 23062412 |
| Inflammation, hepcidin | Altered Intercellular Communication | Preoperative renal function and hemoglobin did not correlate with hepcidin indices whereas plasma markers of inflammation did. | 23062413 |
| Inflammation, Cardiovascular Diseases | Altered Intercellular Communication | Inflammation plays a pivotal role in the pathophysiology of cardiovascular disease, (CVD) and leukotrienes may play a role in atherogenesis. | 23063168 |
| Inflammation, Malignant neoplasm of endometrium | Altered Intercellular Communication | Chronic inflammation may be an important factor in the initiation and promotion of endometrial cancer. | 23063765 |
| Cytomegalovirus Infections, Inflammation, Immune System Diseases | Altered Intercellular Communication | These findings indicate that chronic CMV infection alters the response of aged CD4+ T cells to IL-12 resulting in an increased secretion of IL-21 and that aging affects Tfh cell responses in humans which may contribute to age-associated inflammation and immune dysfunctions. | 23064011 |
| Osteogenesis, Inflammation, Fibrosis Assessment | Altered Intercellular Communication | However, the findings appear to suggest that inflammation and fibrosis were associated with ossification. | 23064569 |
| Inflammation, Immune System Diseases | Altered Intercellular Communication | IL-9-producing CD4(+) T cells (Th9 cells) have been reported to be involved in inflammation and immune diseases. | 23065014 |
| Inflammation, HIV-1 Infection Pathway, HIV-1 | Altered Intercellular Communication | Therefore, drivers of immune activation and inflammation in HIV-1 disease may alter monocyte subpopulations and activation phenotype, contributing to a pro-atherothrombotic state that may drive cardiovascular risk in HIV-1 infection. | 23065151 |
| Inflammation, hepcidin, Anemia | Altered Intercellular Communication | Hepcidin, an important regulator of iron homeostasis, is suggested to be causally related to anemia of inflammation. | 23065507 |
| Inflammation, hepcidin, Anemia, Kidney Diseases | Altered Intercellular Communication | Significantly higher hepcidin levels were found in participants with anemia of inflammation (P<0.01), in participants with anemia of kidney disease (P=0.01), and in participants with unexplained anemia (P=0.01) than in participants without anemia. | 23065507 |
| Inflammation, Anemia, hepcidin | Altered Intercellular Communication | In conclusion, older persons with anemia of inflammation have higher hepcidin levels than their counterparts without anemia. | 23065507 |
| Inflammation, Hemosiderin, Trauma, Nervous System, Axonal degeneration, Vasculitis, Ischemic | Altered Intercellular Communication | Nerve biopsies (11 upper and 11 lower limbs) showed ischaemic injury (axonal degeneration, multifocal fibre loss 15/22, focal perineurial thickening 16/22, injury neuroma 5/22) and increased inflammation (epineural perivascular inflammation 22/22, haemosiderin deposition 6/22, vessel wall inflammation 14/22 and microvasculitis 5/22). | 23065793 |
| Inflammation, Ichthyosis Bullosa of Siemens, NES gene | Altered Intercellular Communication | The pathogenesis of IBS seems to be multifactorial, with the following factors playing a central role in the pathogenesis of IBS: heritability and genetics, dietary/intestinal microbiota, low-grade inflammation, and disturbances in the neuroendocrine system (NES) of the gut. | 23066308 |
| NES gene, Inflammation | Altered Intercellular Communication | Alterations in the NES could be the result of one or more of the following: genetic factors, dietary intake, intestinal flora, or low-grade inflammation. | 23066308 |
| Pain Distress Question, Inflammation, Fever, CTCAE, Urticaria, Erythema, Dyspnea, Laryngeal Edema | Altered Intercellular Communication | Most clinical manifestations observed were: intense burning pain, urticaria, erythema and inflammation (100%), as well dyspnea with laryngeal edema and fever (19%). | 23067562 |
| Necrotizing granulomatous inflammation, Dental Plaque | Altered Intercellular Communication | Increased SUV group had 4 MPM, 5 benign pathology (3 chronic granulomatous inflammation, 2 benign asbestotic plaque). | 23067687 |
| Inflammation, Fibrosis Assessment | Altered Intercellular Communication | Decreased SUV group all had benign pathology (fibrosis, chronic inflammation, myofibrosis). | 23067687 |
| Inflammation, myonecrosis | Altered Intercellular Communication | Influence of platelet reactivity and inflammation on peri-procedural myonecrosis in East Asian patients undergoing elective percutaneous coronary intervention. | 23068571 |
| Carcinogenesis, hepatitis A virus | Altered Intercellular Communication | Chronic inflammatory conditions caused by persistent hepatitis virus infections and interferon (IFN)-g-related immunopathology are known to be related to carcinogenesis. | 23069256 |
| Inflammation, Rectal Prolapse, Rectal polyp | Altered Intercellular Communication | Mucosal prolapse along with chronic inflammation and tissue embedding artifact were the most common features that led to misdiagnosis in rectal serrated polyps. | 23069257 |
| Tumor necrosis, Inflammation | Altered Intercellular Communication | Tumor necrosis factor alfa (TNF-a) is a cytokine with a central role in inflammation. | 23069303 |
| Inflammation, Dermatitis | Altered Intercellular Communication | A punch biopsy specimen demonstrated vacuolar interface dermatitis and lymphohistiocytic perivascular inflammation. | 23069957 |
| Inflammatory abnormality of the eye, Ocular Toxoplasmosis | Altered Intercellular Communication | Ocular inflammation does not mean reactivation of ocular toxoplasmosis. | 23070707 |
| Chronic liver disease, Portal inflammation | Altered Intercellular Communication | Six cases were associated with chronic liver disease and the remaining 4 cases showed mild fatty change in the parenchyma and/or minimal to mild portal inflammation. | 23073321 |
| Hyperglycemia, Inflammation, Complications of Diabetes Mellitus | Altered Intercellular Communication | Glucose ingestion-induced hyperglycemia has been known to induce inflammation, which is related to the pathogenesis of diabetic complications. | 23073386 |
| Inflammation, Complications of Diabetes Mellitus | Altered Intercellular Communication | We believe that these results will provide some basic insight into the role of leukocytes in hyperglycemia-induced inflammation and the pathogenesis of diabetic complications. | 23073386 |
| Inflammation, Osteopenia | Altered Intercellular Communication | A sufficient width of keratinized peri-implant mucosa is important to prevent peri-implant bone loss and inflammation. | 23075057 |
| Inflammation | Altered Intercellular Communication | Interleukin-18 (IL-18) is a member of the IL-1 cytokine family that affects chronic inflammation. | 23075512 |
| Inflammation, Craniosynostosis | Altered Intercellular Communication | These results suggest that the pro-inflammatory effect of IL-18 released by danger signals may be involved in the pathogenesis of CRS, which includes eosinophilic inflammation and NP formation, via the augmentation of both Th2- and Th1-associated cytokine production. | 23075512 |
| Inflammation, Cardiovascular Diseases | Altered Intercellular Communication | Red blood cell distribution width (RDW) is a novel prognostic marker that reflects oxidative stress and chronic inflammation in patients with cardiovascular disease. | 23075764 |
| vascular inflammations, Diabetes Mellitus, Atherosclerosis | Altered Intercellular Communication | Diabetes mellitus increases oxidative stress and vascular inflammation, which accelerate atherosclerosis. | 23075764 |
| Fibrosis Assessment, Hepatitis, Chronic | Altered Intercellular Communication | Progression of chronic liver inflammation and fibrosis driven by activation of c-JUN signaling in Sirt6 mutant mice. | 23076146 |
| Tissue damage, Inflammation, Virus Diseases | Altered Intercellular Communication | The human body has a remarkable ability to regulate inflammation, a biophysical response triggered by virus infection and tissue damage. | 23076146 |
| Inflammation | Altered Intercellular Communication | Sirt6 is critical for metabolism and lifespan; however, its role in inflammation is unknown. | 23076146 |
| Hepatitis, Chronic | Altered Intercellular Communication | Here we show that Sirt6-null (Sirt6(-/-)) mice developed chronic liver inflammation starting at ~2 months of age, and all animals were affected by 7-8 months of age. | 23076146 |
| Fibrosis Assessment, Hepatitis | Altered Intercellular Communication | Deletion of Sirt6 in T cells or myeloid-derived cells was sufficient to induce liver inflammation and fibrosis, albeit to a lesser degree than that in the global Sirt6(-/-) mice, suggesting that Sirt6 deficiency in the immune cells is the cause. | 23076146 |
| Inflammation, Anemia | Altered Intercellular Communication | Concurrent inflammation or anemia at the time of PET/computed tomography (CT) could be one of several causes of diffuse splenic (18)F-fluorodeoxyglucose ((18)F-FDG) uptake. | 23076270 |
| ARTERIAL TORTUOSITY SYNDROME, Inflammation, Venous Stroke, Atherosclerosis | Altered Intercellular Communication | Atherosclerosis is an important pathophysiological basis of atherothrombotic stroke (ATS), and inflammation plays a significant role in atherosclerosis formation. | 23076369 |
| Inflammation, Necrosis | Altered Intercellular Communication | Biomarkers of necrosis and inflammation have been found raised after radiofrequency ablation (RF). | 23078110 |
| Inflammation, Rheumatoid Arthritis | Altered Intercellular Communication | Interleukin-29 modulates proinflammatory cytokine production in synovial inflammation of rheumatoid arthritis. | 23078630 |
| Inflammation, Sepsis, Tissue damage, Single organ dysfunction, GTF2A1L wt Allele, Liver Failure, Acute | Altered Intercellular Communication | Systemic inflammation and susceptibility to developing sepsis is common in acute liver failure (ALF) resulting in tissue damage and organ failure. | 23079896 |
| Inflammation, Ectropion | Altered Intercellular Communication | Eye-washing methods without eyelid eversion are more effective in reducing conjunctival bacteria before surgery and anterior chamber inflammation after surgery than those with eyelid eversion. | 23080269 |
| Cessation of life, Steatohepatitis, Liver damage, Inflammation | Altered Intercellular Communication | Aging does not promote the development of hepatic steatosis but leads to increased hepatocellular injury and inflammation that may be due in part to sensitization to the Fas death pathway and increased M1 macrophage polarization. | 23081825 |
| Inflammation, Glucocorticoid deficiency with achalasia, Aortic Aneurysm, Abdominal, Rupture | Altered Intercellular Communication | Mycotic abdominal aortic aneurysms (AAAs) are a clinical challenge for vascular surgeons due to their critical location, surrounding inflammation, risk of rupture, and danger of reinfection following treatment. | 23081891 |
| Abdomen, Acute, Chief complaint (finding), Acute inflammation, Anisakiasis | Altered Intercellular Communication | In patients with a recent history of eating raw marine fish presenting with acute onset of abdominal complaints and CT features of acute small bowel inflammation the possibility of anisakiasis should be considered in the differential diagnosis of acute abdominal syndromes. | 23082711 |
| Inflammation, Prostate carcinoma | Altered Intercellular Communication | Chronic asymptomatic inflammation of the prostate type IV and carcinoma of the prostate: is there a correlation? | 23082817 |
| Inflammation | Altered Intercellular Communication | Chronic inflammation was verified in 43.86% of the RPE group, compared to 70.74% of the BPH group (p < 0.001). | 23082817 |
| TNM Staging System, Inflammation, Neoplasms | Altered Intercellular Communication | Gleason score distribution (5-9) and tumour stage (TNM) were similar in the inflammation and non-inflammation groups (p < 0.99, p < 0.21). | 23082817 |
| Prostate carcinoma, prostatitis | Altered Intercellular Communication | No significant correlation between chronic prostatic inflammation and carcinoma of the prostate was detected. | 23082817 |
| Inflammation, Primary malignant neoplasm | Altered Intercellular Communication | The NLR, an index of systemic inflammation, is associated with outcome in several cancer types. | 23083797 |
| Inflammation, Impaired lung function | Altered Intercellular Communication | Systemic inflammation is associated with impaired lung function. | 23083841 |
| Inflammation, Thromboembolic stroke | Altered Intercellular Communication | Higher NLR, an emerging marker of inflammation, is associated with thromboembolic stroke in non-valvular AF patients. | 23084070 |
| Intraocular inflammation | Altered Intercellular Communication | To describe an outbreak of intraocular inflammation caused by endotoxin-contaminated counterfeit bevacizumab in China. | 23084126 |
| Intraocular inflammation | Altered Intercellular Communication | The medical records and microbiology results of patients who presented with intraocular inflammation after injection with intravitreal counterfeit bevacizumab were reviewed. | 23084126 |
| Intraocular inflammation, Inflammation | Altered Intercellular Communication | The incidence of intraocular inflammation, results of pathogen cultures, and clinical features of inflammation. | 23084126 |
| Hypopyon, Vitreous inflammatory cells | Altered Intercellular Communication | Twenty-one patients with hypopyon and significant vitreous inflammation underwent vitrectomy. | 23084126 |
| Inflammation, Endothelial dysfunction | Altered Intercellular Communication | Chronic inflammation has been associated with endothelial dysfunction and altered coagulation status. | 23085092 |
| Inflammation | Altered Intercellular Communication | In cardiac patients positive affect has found to be associated with improved clinical outcomes, with reduced inflammation being one of the potential mechanisms responsible. | 23085133 |
| Inflammation, Heart failure | Altered Intercellular Communication | Positive affect is associated with reduced inflammation in patients with heart failure. | 23085133 |
| Inflammation, Brain Injuries, Osteochondritis Dissecans, Postoperative cognitive dysfunction | Altered Intercellular Communication | We hypothesized that different patterns of biomarkers of brain injury and inflammation exist in aged patients with postoperative cognitive dysfunction (POCD) after total hip-replacement with spinal anesthesia. | 23085747 |
| Inflammation, Carcinogenesis, Stomach Carcinoma | Altered Intercellular Communication | Chronic inflammation and gastric carcinogenesis show a close association, so gene polymorphisms that modify the intensity of the inflammatory response may contribute to variations in gastric cancer risk. | 23086128 |
| Pain Distress Question, Inflammation | Altered Intercellular Communication | Ibuprofen is a non-selective cyclo-oxygenase (COX)-1/COX-2 inhibitor used to treat pain conditions and inflammation. | 23086696 |
| Inflammation, Paraproteinemias, Autoinflammatory disorder, Urticaria | Altered Intercellular Communication | Schnitzler's syndrome is a chronic disabling autoinflammatory disorder, characterised by chronic urticaria, paraproteinemia and systemic inflammation. | 23087179 |
| Inflammation, acute diverticulitis | Altered Intercellular Communication | The value of inflammation markers and body temperature in acute diverticulitis. | 23088216 |
| Inflammation, Atherosclerosis | Altered Intercellular Communication | Fish consumption, omega-3 fatty acids, and environmental contaminants in relation to low-grade inflammation and early atherosclerosis. | 23089109 |
| Inflammation, Atherosclerosis | Altered Intercellular Communication | Our aim was to elucidate the associations of fish consumption, omega-3 PUFAs, environmental contaminants with low-grade inflammation, early atherosclerosis, and traditional CVD risk factors. | 23089109 |
| Inflammation, Depressed mood, Depression, CTCAE, Metabolic Syndrome X | Altered Intercellular Communication | Evidence for a differential role of HPA-axis function, inflammation and metabolic syndrome in melancholic versus atypical depression. | 23089630 |
| Mastitis, Inflammation, Caseous necrosis | Altered Intercellular Communication | Histopathological examination revealed features of mastitis with epithelioid histiocytes and Langhans giant cells and was characterized by the presence of caseous necrosis which suggested tuberculous inflammation. | 23089809 |
| Hypermobility, Inflammation | Altered Intercellular Communication | Further studies demonstrated hypermobility with adjacent soft-tissue reactivity and inflammation surrounding the right T5 transpedicle screw. | 23089930 |
| Inflammation | Altered Intercellular Communication | Compared to subcutaneous fat, visceral fat is more metabolically active, leading to chronic inflammation and tumorigenesis. | 23090279 |
| Refractory anemias | Altered Intercellular Communication | HR-pQCT provides new insight into inflammation-associated bone fragility in RA. | 23090909 |
| Tissue damage, Inflammation | Altered Intercellular Communication | "Surgical stress response" is tissue damage postsurgery, leading to a systemic response (inflammation, sympathetic upregulation, and release of vasoactive chemicals), which is typically measured by C-reactive protein (CRP). | 23091271 |
| Inflammation, Diabetes Mellitus, Non-Insulin-Dependent, Atherosclerosis | Altered Intercellular Communication | Activation of the innate immune system and subsequent chronic low-grade inflammation are thought to be involved in the pathogenesis of atherosclerosis and type 2 diabetes. | 23091345 |
| Atherosclerosis | Altered Intercellular Communication | Atherosclerosis is an inflammatory condition and increased blood levels of inflammatory biomarkers have been observed in acute coronary syndromes. | 23091596 |
| Inflammation, Metabolic Syndrome X | Altered Intercellular Communication | Excess visceral fat causes local chronic low-grade inflammation and dysregulation of adipocytokines, which contribute in the pathogenesis of the metabolic syndrome. | 23091619 |
| Inflammation, Atherosclerosis | Altered Intercellular Communication | Assay panels for biomarkers associated with atherosclerosis biology (inflammation, angiogenesis, apoptosis, chemotaxis, etc.) | 23092312 |
| Aneurysm, CDIPT gene, Fever, CTCAE, Inflammation | Altered Intercellular Communication | In patients undergoing endovascular aneurysm repair (EVAR), the postimplantation syndrome (PIS), comprising fever and inflammation, occurs frequently. | 23092643 |
| CLU protein, human, Ischemia, Inflammation | Altered Intercellular Communication | We hypothesise that severe ischaemia and/or prolonged inflammation in CLI might lead to a paradoxical attenuation in the proinflammatory membrane pattern of circulating mononuclear cells, possibly hindering an adequate regulatory function of mDCs and pDCs and favouring the progression of disease. | 23093299 |
| Impaired T cell function | Altered Intercellular Communication | In conclusion, common variation in MAP4K4 is associated with insulin resistance and b-cell dysfunction, possibly via this gene's role in inflammatory signalling. | 23094072 |
| Inflammation, Metabolic Diseases, Malnutrition, Chronic Kidney Diseases | Altered Intercellular Communication | Protein-calorie malnutrition as well as systemic inflammation and metabolic disorders are common among patients with chronic renal failure undergoing renal replacement therapy (hemodialysis), which contributes to their morbidity and mortality. | 23094520 |
| Erectile dysfunction | Altered Intercellular Communication | Erectile dysfunctions (EDs) are in part caused by hormonal causes; but in men over 65 years of age, testosterone deficiency seems to play an important role. | 23094956 |
| Inflammation, Spondylitis, Pain Distress Question | Altered Intercellular Communication | At week 12 the Bath Ankylosing Spondylitis Disease activity spinal inflammation score decreased by 65% (P <0.001), the back pain score decreased by 50% (P <0.005), the Bath AS Functional Index (BASFI) score decreased by 47% (P <0.02), while the Childhood Health Assessment Questionnaire-Disability Index (CHAQ-DI) score improved by 65% (P <0.005). | 23095307 |
| Inflammation | Altered Intercellular Communication | Rebound of choroidal thickening was observed in three patients (five eyes) during corticosteroid tapering in the absence of other evidence of increased inflammation. | 23095726 |
| Choroiditis | Altered Intercellular Communication | Choroidal thickness as measured by EDI-OCT may serve as a marker for degree of choroidal inflammation in acute VKH disease. | 23095726 |
| Diabetic Retinopathy, Inflammatory abnormality of the eye | Altered Intercellular Communication | The pathogenesis of diabetic retinopathy has been suggested to be associated with ocular inflammation. | 23095769 |
| Tissue damage | Altered Intercellular Communication | Interleukins, interferons and oxidative DNA products are important biomarkers assessing the inflammations and tissue damages caused by toxic materials in the body. | 23096020 |
| Inflammation | Altered Intercellular Communication | Cytokines, such as interleukin 10 (IL10), play an important role in the process of inflammation. | 23096091 |
| ARCN1 gene, Inflammation, exacerbation acute | Altered Intercellular Communication | This raise may be related directly to COPD and its associated systemic inflammation or secondary to other factors such as smoking status, disease severity, acute exacerbations, or associated complications. | 23096661 |
| Sepsis, Communicable Diseases, Inflammation | Altered Intercellular Communication | In addition to their beneficial effects against infection, NK cells may play a detrimental role during systemic inflammation, causing lethality during sepsis. | 23098236 |
| Inflammation, Electrocardiogram: myocardial infarction (finding) | Altered Intercellular Communication | [The role of markers of inflammation in assessment of prognosis in patients with ST-elevation myocardial infarction combined with disturbances of carbohydrate metabolism]. | 23098394 |
| Inflammation, Low Grade Squamous Intraepithelial Neoplasia | Altered Intercellular Communication | MLBC was more sensitive in diagnosis of LSIL and more specific in the diagnosis of inflammation. | 23098448 |
| Inflammation, Apolipoprotein E | Altered Intercellular Communication | Apolipoprotein E (ApoE) is a multifunctional protein playing both a key role in the metabolism of cholesterol and triglycerides, and in tissue repair and inflammation. | 23098561 |
| Inflammation | Altered Intercellular Communication | In the following 12 months he required 5 major surgeries due to a process of systematic inflammation/infection throughout different locations of the DBS system. | 23098765 |
| Inflammation, Impaired cognition, Abnormality of the vasculature | Altered Intercellular Communication | Given these results, there is a possibility that inflammation and cerebrovascular abnormalities might be the cause of cognitive decline in this model. | 23099816 |
| Pneumonitis | Altered Intercellular Communication | Recovery of neutrophil apoptosis by ectoine: a new strategy against lung inflammation. | 23100492 |
| Pneumonitis | Altered Intercellular Communication | The life span of neutrophilic granulocytes has a determining impact on the intensity and duration of neutrophil driven lung inflammation. | 23100492 |
| Pneumonitis | Altered Intercellular Communication | Neutrophilic lung inflammation induced by single or multiple expositions of animals to environmental particles was reduced after the therapeutic intervention with ectoine. | 23100492 |
| Airway structure | Altered Intercellular Communication | Are these results related to changes in distinct markers of airway inflammation and extracellular remodelling? | 23100503 |
| Inflammation, Observation Method - Coagulation, Diabetes Mellitus, Non-Insulin-Dependent | Altered Intercellular Communication | Association of physical activity with insulin resistance, subclinical inflammation, coagulation, and fibrinolytic biomarkers among population at high risk for type 2 diabetes. | 23101283 |
| Inflammation, Observation Method - Coagulation, Diabetes Mellitus, Non-Insulin-Dependent | Altered Intercellular Communication | TO investigate the association of physical activity with insulin resistance and biomarkers of inflammation, coagulation, and fibrinolysis in a population at high risk for type 2 diabetes. | 23101283 |
| Inflammation, Metabolic Syndrome X | Altered Intercellular Communication | Single nucleotide polymorphisms (SNPs) involved in insulin resistance, weight regulation, lipid metabolism and inflammation in relation to metabolic syndrome: an epidemiological study. | 23101478 |
| Inflammation, Metabolic Syndrome X, ETV3 wt Allele | Altered Intercellular Communication | Mechanisms involved in metabolic syndrome (MetS) development include insulin resistance, weight regulation, inflammation and lipid metabolism. | 23101478 |
| Inflammation, ETV3 wt Allele | Altered Intercellular Communication | The groups of inflammation and lipid SNPs were neither associated with presence of MetS nor with MetS score. | 23101478 |
| Ichthyosis Bullosa of Siemens, Functional disorder, Gastrointestinal inflammation, Irritable Bowel Syndrome | Altered Intercellular Communication | The traditional classification of irritable bowel syndrome (IBS) as a functional disorder has been challenged in recent years by evidence of ongoing low-grade gastrointestinal tract inflammation. | 23102771 |
| Inflammation, Ichthyosis Bullosa of Siemens | Altered Intercellular Communication | Inflammation may alter gastrointestinal motility and thus be central to the pathogenesis of IBS. | 23102771 |
| Inflammation, "Alzheimers Disease", Data types - Address | Altered Intercellular Communication | Is increased red cell distribution width (RDW) indicating the inflammation in Alzheimer's disease (AD)? | 23103090 |
| Inflammation, Data types - Address | Altered Intercellular Communication | Increasing evidence indicates that inflammation has a substantial role in the pathogenesis and progression of AD. | 23103090 |
| Inflammation, Data types - Address | Altered Intercellular Communication | Whereas elevated RDW value is usually considered as a novel biomarker of inflammation, the results of our study may support the role of inflammation in pathophysiology of AD. | 23103090 |
| Communicable Diseases, Inflammation, Leprosy | Altered Intercellular Communication | Identification of IL18RAP/IL18R1 and IL12B as leprosy risk genes demonstrates shared pathogenesis between inflammation and infectious diseases. | 23103228 |
| Uremia, Inflammation, Diabetic Angiopathies, Diabetes Mellitus | Altered Intercellular Communication | Carbonylation of the protein amino, guanidine, and thiol groups with a-oxoaldehydes (which are produced in higher quantities in diabetes, uremia, oxidative stress, aging, and inflammation) is one of the important causes of vascular complications. | 23103397 |
| Inflammation | Altered Intercellular Communication | Furthermore, MMP-2, MMP-9 (p < 0.04) and elastase in group B showed faster and greater decrease in levels, compared with group A, indicating a faster and superior reduction of inflammation. | 23103485 |
| Refractory anemias, Inflammation | Altered Intercellular Communication | For optimal RA management, the current recommendation is to adapt DMARD therapy to the level of inflammation and not only of patient complaints. | 23104976 |
| Tissue damage, Inflammation, Hyperpigmentation | Altered Intercellular Communication | Inflammation drives wound hyperpigmentation in zebrafish by recruiting pigment cells to sites of tissue damage. | 23104990 |
| Inflammation | Altered Intercellular Communication | We discuss the theoretical possibility that foreskin inflammation compromises the mucosal/epithelial barrier, thus playing a role in disease transmission. | 23106553 |
| Region of nasal process, Ear Inflammation, allergic inflammation, IL13 gene, effusion | Altered Intercellular Communication | Otitis media with effusion is closely associated with allergic rhinitis presumably caused by allergic inflammation, but not mechanical nasal mucosal swelling. | 23106661 |
| Malignant neoplasm of esophagus, Inflammation, Primary malignant neoplasm, Cancer-Related Death | Altered Intercellular Communication | Esophageal cancer is the seventh leading cause of cancer death in males in USA, and there is a strong link has been demonstrated between inflammation and esophageal cancer, interleukin (IL)-32 is a recently described pro-inflammatory cytokine characterized by the induction of nuclear factor NF-kB activation, the p38MAPK also plays an important role in key cellular processes related to inflammation and cancer. | 23107826 |
| Inflammation, Ischemia | Altered Intercellular Communication | We have found that oxidative stress and inflammation were increased and antioxidative defense was decreased, which resulted in increased levels of IMA, a biomarker of ischemia, in obese subjects. | 23108391 |
| Inflammation, Fibrosis Assessment, Fatty degeneration | Altered Intercellular Communication | Biopsy samples from 18 patients (33%) showed nearly normal histology with no inflammation, fibrosis, or steatosis. | 23109058 |
| Inflammation, Fibrosis Assessment, Cholestasis | Altered Intercellular Communication | The fibrosis stage correlated negatively with serum prealbumin levels (r = -0.364, P = 0.007) and positively with chronic cholestasis (cytokeratin 7 staining; r = 0.529, P < 0.001) and portal inflammation (r = 0.350, P = 0.01). | 23109058 |
| Herpes Zoster Ophthalmicus, Orbital Myositis, Optic Neuritis | Altered Intercellular Communication | Painful ophthalmoplegia with simultaneous orbital myositis, optic and oculomotor nerve inflammation and trigeminal nucleus involvement in a patient with herpes zoster ophthalmicus. | 23109414 |
| Inflammation, Metabolic Syndrome X | Altered Intercellular Communication | The role of metabolic syndrome, adiposity, and inflammation in physical performance in the Health ABC Study. | 23109678 |
| Inflammation, Metabolic Syndrome X, ETV3 wt Allele | Altered Intercellular Communication | Metabolic syndrome (MetS) and functional limitation have been linked, but whether and how specific components of MetS and associated factors, such as inflammation, drive this relationship is unknown. | 23109678 |
| Inflammation, Fibrosis Assessment | Altered Intercellular Communication | Recently, it has been hypothesized that inflammasomes could have a crucial role in the host response to silica and recent studies show that the inflammasome contributes to inflammation and pulmonary fibrosis. | 23110140 |
| Inflammation, Traumatic injury | Altered Intercellular Communication | The presence of thick attached keratinized tissue around implants may constitute a protective factor against marginal inflammation or trauma. | 23110330 |
| Congenital Abnormality | Altered Intercellular Communication | No signs of hormonal deficency was shown authorizing us to approach the disease as a congenital malformation due to an abnormality of intrauterine development. | 23110911 |
| Inflammation, Damage, Rheumatoid Arthritis, MTTP wt Allele | Altered Intercellular Communication | Low-field MRI versus ultrasound: which is more sensitive in detecting inflammation and bone damage in MCP and MTP joints in mild or moderate rheumatoid arthritis? | 23111117 |
| Refractory anemias, Inflammation, Rheumatoid Arthritis | Altered Intercellular Communication | The aim of the present paper is to determine if the ultrasound of hands and feet is comparable to the MRI of the dominant hand to detect erosive disease and inflammation in mild or moderate rheumatoid arthritis (RA). | 23111117 |
| Lymphoproliferative Disorders, Orbital Pseudotumor | Altered Intercellular Communication | To determine whether serologic factors correlate with early relapse in cases of IgG4-related orbital inflammation, a lymphoproliferative disorder. | 23111178 |
| Rheumatoid Factor, Orbital Pseudotumor | Altered Intercellular Communication | The serum rheumatoid factor level may correlate with proliferative activity in IgG4-related orbital inflammation. | 23111178 |
| Inflammation, Necrosis | Altered Intercellular Communication | Adequate biopsy is required for a diagnosis because this lymphoma frequently coexists with large amount of necrosis and inflammation. | 23111392 |
| HD Term Type, Inflammation | Altered Intercellular Communication | FID is present in a substantial proportion of patients on HD, who thus should be screened for reversible causes of inflammation. | 23111696 |
| Uremia, Inflammation | Altered Intercellular Communication | Thus, the higher concentration of cC characteristic for uremic patients may modulate acute inflammation through maintaining PMN longevity and inhibiting their respiratory burst and proinflammatory cytokine-related changes in cC release from PMNs. | 23111743 |
| Familial benign pemphigus, Inflammation, Myocarditis, CTCAE 5.0 | Altered Intercellular Communication | PCR was negative in HHD without inflammation while it was positive in 10 subjects with myocarditis (enterovirus in 3 cases, adenovirus 4, influenza virus 3). | 23112000 |
| Granulomatous inflammation | Altered Intercellular Communication | Histopathology of tracheobronchial nodules and bronchial mucosa biopsy specimen both showed granulomatous inflammation with proliferation of capillaries and inflammatory cells. | 23112563 |
| Hepatitis | Altered Intercellular Communication | Galectin-9 was detectable at increased concentrations in the sera of patients with active CHB-related liver inflammation (p = 0.02) and was strongly expressed by Kupffer cells within the liver sinusoidal network. | 23112829 |
| Immunologic Deficiency Syndromes, Inflammation, Traumatic injury | Altered Intercellular Communication | Authors draw attention to possibility of other etiological agents for BCC like local trauma, ageing, ionizing radiation, arsenic, chronic inflammation, and immune deficiency. | 23113607 |
| Arthritis | Altered Intercellular Communication | Maori and Pacific participants had earlier age of onset (by 9 years), higher flare frequency and more features of joint inflammation. | 23114632 |
| Inflammation | Altered Intercellular Communication | A dysfunction of the rich neural plexus around the ductules may play a role in the development of dacryops in conjunction with periductular inflammation and induced scarring. | 23114708 |
| Inflammation, Malignant neoplasm of gastrointestinal tract | Altered Intercellular Communication | Nutritional status, systemic inflammation and prognosis of patients with gastrointestinal cancer. | 23114934 |
| Communicable Diseases, Inflammation | Altered Intercellular Communication | High prevalence values were found for systemic inflammation (73%), a greater risk of infectious and/or inflammatory complication (43%) and worse prognosis (50%). | 23114934 |
| Inflammation, Malignant neoplasm of gastrointestinal tract | Altered Intercellular Communication | Nutritional status is related to inflammation markers and prognosis in patients with gastrointestinal cancer. | 23114934 |
| Inflammation, Nephrolithiasis | Altered Intercellular Communication | 108 patients aged from 18 to 59 years (mean age - 40.26 +/- 10.09 years) with secondary CPN against dysmetabolic nephropathy and nephrolithiasis in a phase of active inflammation were observed. | 23116015 |
| Inflammation, Cyclophosphamide/Vincristine/Dacarbazine Regimen, Cardiovascular Diseases | Altered Intercellular Communication | Dispositional hostility as measured by the Cook Medley Hostility (Ho) Scale has been associated with inflammation and cardiovascular disease (CVD) risk. | 23116190 |
| Colorectal Carcinoma | Altered Intercellular Communication | Inflammation-based prognostic system predicts survival after surgery for stage IV colorectal cancer. | 23116639 |
| Inflammation Mediators | Altered Intercellular Communication | Future research using these techniques will aid further understanding of the inflammation-mediated bony changes associated with development and progression of CN and other diseases. | 23117208 |
| Demographics Domain, Congenital Abnormality, Diabetes Mellitus, Ulceration, CTCAE, Neurogenic arthropathy, Peripheral Neuropathy | Altered Intercellular Communication | Charcot neuroarthropathy (CN), an inflammatory condition characterized by rapid and progressive destruction of pedal bones and joints, often leads to deformity and ulceration in individuals with diabetes mellitus (DM) and peripheral neuropathy (PN). | 23117208 |
| Inflammation, Malignant Neoplasms | Altered Intercellular Communication | The interleukin-6 (IL-6) pathway is one of the mechanisms that link inflammation and angiogenesis with malignancy. | 23117246 |
| Inflammation, Primary malignant neoplasm | Altered Intercellular Communication | Since nuclear factor-kB (NF-kB) is a potential sign for inflammation, NF-kB has been associated with the progression of disease in various types of cancer. | 23117246 |
| Cataract, Inflammation | Altered Intercellular Communication | Additional complications observed were cataract progression requiring surgery (42%), persistent intraocular pressure elevation (36%), and transient inflammation (32%). | 23117281 |
| Neoplastic, Fibrosis Assessment, Inflammation, Anthracosis | Altered Intercellular Communication | A final diagnosis of fibrosis associated with anthracosis was made, and neither active inflammation nor neoplastic lesion was not demonstrated. | 23117360 |
| Damage | Altered Intercellular Communication | Inflammation-induced and stress-related cardiac damage are increasingly recognized in patients with critical illness. | 23117374 |
| Pain Distress Question, Swelling, Inflammation | Altered Intercellular Communication | Pain, swelling and inflammation are expected during the recovery from total knee arthroplasty (TKA) surgery. | 23118406 |
| Inflammation | Altered Intercellular Communication | Inflammation is part of a complex biological response of vascular tissue to pathogens or damaged cells. | 23119050 |
| Inflammation, Hypoxia | Altered Intercellular Communication | Hypoxia and p38-MAPK are associated with inflammation, and hypoxia inducible factor 1 (HIF-1) has been detected in inflamed tissues. | 23119050 |
| Inflammation, Primary malignant neoplasm, Non-Cancer Related Death | Altered Intercellular Communication | After endoscopy each patient was assigned into one of two groups: (1) non-cancer, including inflammation; (2) cancer group. | 23119113 |
| Inflammation, Esophageal carcinoma | Altered Intercellular Communication | The AFI displayed mucosal inflammation and carcinomas of esophagus and stomach as dark red color, the normal mucosa background was displayed as light green. | 23119113 |
| Inflammation, Hepatitis | Altered Intercellular Communication | The pattern of cytokines and chemokines in sera was linked to HBV viral load and was consistent with the level of inflammation during chronic hepatitis. | 23121366 |
| Pulmonary Emphysema, Inflammation, Atelectasis, Hyperemia | Altered Intercellular Communication | Early emphysema is associated with elevated tissue volume and FTV, consistent with hyperemia, inflammation or atelectasis. | 23122057 |
| Inflammation, Fibrosis Assessment | Altered Intercellular Communication | Diagnostic performance of conventional diffusion weighted imaging and diffusion tensor imaging for the liver fibrosis and inflammation. | 23122674 |
| Compact Disk Interactive, Inflammation, Fibrosis, Liver | Altered Intercellular Communication | To evaluate the diagnostic accuracy of liver apparent diffusion coefficient (ADC) measured with conventional diffusion-weighted imaging (CDI) and diffusion tensor imaging (DTI) for the diagnosis of liver fibrosis and inflammation. | 23122674 |
| Inflammation, Fibrosis Assessment | Altered Intercellular Communication | Histopathologically, fibrosis of the liver parenchyma was classified with the use of a 5-point scale (0-4) and inflammation was classified with use of a 4-point scale (0-3) in accordance with the METAVIR score. | 23122674 |
| Inflammation, Fibrosis Assessment | Altered Intercellular Communication | Quantitatively, signal intensity and the ADCs of the liver parenchyma were compared between patients stratified by fibrosis stage and inflammation grade. | 23122674 |
| Inflammation, Fibrosis Assessment | Altered Intercellular Communication | Liver ADC values inversely correlated with fibrosis and inflammation but there was only statistically significant for inflammatory grading. | 23122674 |
| Compact Disk Interactive, Inflammation, Fibrosis Assessment | Altered Intercellular Communication | CDI performed better than DTI for the diagnosis of fibrosis and inflammation. | 23122674 |
| Inflammation, NEUROTICISM, GDC Comorbidity Terminology, Conscious, Obesity | Altered Intercellular Communication | Adjustment for health behaviors diminished the magnitude of this association but did not eliminate it, suggesting that lower comorbid conditions and obesity may partly explain the lower inflammation of those high in both Conscientiousness and Neuroticism. | 23123863 |
| Inflammation | Altered Intercellular Communication | Using personality to identify those at risk may lead to greater personalization in the prevention and remediation of chronic inflammation. | 23123863 |
| Refractory anemias, Rheumatoid Arthritis, Inflammation, Pain Distress Question | Altered Intercellular Communication | Among rheumatoid arthritis (RA) patients, the intensity of pain may be out of proportion to the severity of peripheral inflammation. | 23124650 |
| Refractory anemias, Inflammation, Dyssomnias | Altered Intercellular Communication | Sleep problems, mental health, and inflammation were assessed as mediators of the relationship between RA and QST outcomes. | 23124650 |
| Inflammation | Altered Intercellular Communication | It is hypothesized that their appearance could be provoked by either increased erythropoiesis or bone marrow micro-architectural damage mostly caused by inflammation and/or decreased tissue oxygenation. | 23126050 |
| Inflammation, Primary malignant neoplasm, Communicable Diseases, Rheumatoid Arthritis, Reactive systemic amyloidosis | Altered Intercellular Communication | Secondary amyloidosis (AA) is a rare but serious complication that appears in the context of cancer, chronic inflammation, and chronic infectious disease, including rheumatoid arthritis. | 23126056 |
| ARCN1 gene, Inflammation, Lung Injury | Altered Intercellular Communication | Increased CD4(+)IL-17(+) cell number in lung tissue is involved in chronic inflammation of the lungs and parallels lung injury aggravation in COPD patients and in smokers without airway limitations. | 23127823 |
| Communicable Diseases, Inflammation | Altered Intercellular Communication | Any kind of infection or inflammation was an exclusion criterion. | 23128367 |
| Retinitis | Altered Intercellular Communication | These findings suggest that PEDF accelerated the recovery of tear secretion and also prevented neurotrophic keratouveitis and vitreoretinal inflammation. | 23128960 |
| Inflammation, Takayasu Arteritis | Altered Intercellular Communication | Takayasu arteriitis (TA) was clinically diagnosed and confirmed by MR angiography and FDG-PET scan showing inflammation of the aortic arch and the left subclavian artery. | 23129041 |
| Inflammation | Altered Intercellular Communication | Immunosuppression with glucocorticoids and methotrexate resulted in immediate clinical improvement and normalization of systemic markers of inflammation. | 23129041 |
| Inflammation | Altered Intercellular Communication | This case shows that vascular progress in TA patients may occur even when systemic inflammation is controlled, therefore patients have to be carefully observed for new vascular manifestations. | 23129041 |
| Electrocardiogram: myocardial infarction (finding), Depression, CTCAE | Altered Intercellular Communication | Disturbance of serotonergic neurotransmission in patients with postmyocardial infarction and depression. | 23129293 |
| ARCN1 gene, Inflammation, Sarcopenia, Osteopenia | Altered Intercellular Communication | Comorbidities of COPD include increased risk of cardiovascular (CV) disease, loss of bone mineral density (BMD) and loss of skeletal muscle mass and function, all linked to systemic inflammation. | 23129800 |
| Arterial Stiffness, Inflammation, Bronchiectasis | Altered Intercellular Communication | Patients with bronchiectasis had increased arterial stiffness (an indicator of increased CV risk), increased inflammation, reduced exercise capacity and bone thinning. | 23129800 |
| Inflammation | Altered Intercellular Communication | Survivors with MS have features of inflammation and prothrombotic state, increased carotid artery intima-media thickness. | 23131388 |
| Inflammation, Malnutrition, Xerostomia, Chronic Kidney Diseases | Altered Intercellular Communication | Chronic kidney disease is associated with inflammation, oxidative stress, malnutrition, poor oral health, and mouth dryness. | 23131570 |
| Inflammation, Osteoporosis | Altered Intercellular Communication | In conclusion, variation in inflammatory genes CIITA, CLEC-16A and INFG appear to contribute to bone phenotypes in elderly women and suggest a role for low-grade inflammation and MHC class II expression for osteoporosis pathogenesis. | 23133532 |
| Inflammation, Helicobacter pylori, Dysplasia, Communicable Diseases, Pancreatic aplasia, Intestinal metaplasia | Altered Intercellular Communication | The maximal lengths of CLE and superficial esophageal glands (SEG) and the presence or absence of chronic inflammation (CI), lymphoid follicles (LF), Helicobacter pylori (H. pylori) infection, intestinal metaplasia (IM), pancreatic metaplasia (PM) and dysplasia were analyzed and compared with those in the adjacent proximal gastric mucosa. | 23134360 |
| Cerebral Amyloid Angiopathy, Inflammation, Pathology, "Alzheimers Disease", Data types - Address | Altered Intercellular Communication | Alzheimer's disease (AD) and cerebral amyloid angiopathy (CAA) are two common pathologies associated with b-amyloid (Ab) accumulation and inflammation in the brain; neither is well understood. | 23134465 |
| Communicable Diseases, Inflammation, Malignant Neoplasms, Disturbance | Altered Intercellular Communication | On the other hand, C-reactive protein (CRP) and serum amyloid A (SAA) are acute inflammatory biomarkers that increase in various conditions including infection, inflammation, malignancy and tissue disturbance. | 23135313 |
| Inflammation, Ulcerative Colitis | Altered Intercellular Communication | Ulcerative colitis (UC) is a chronic condition characterised by the relapsing inflammation despite previous endoscopic and histological healing. | 23135761 |
| Inflammation, Neuropathy, Edema, Strangulation, Palsy | Altered Intercellular Communication | Bell palsy is considered to be an entrapment neuropathy resulting from inflammation, edema, and strangulation. | 23136321 |
| Stomach Carcinoma, Communicable Diseases, Helicobacter pylori, Inflammation | Altered Intercellular Communication | Gastric cancer is supposed to be a result of inflammation induced by Helicobacter pylori (H. pylori) infection. | 23136938 |
| Chronic neuropathic pain | Altered Intercellular Communication | Mediators produced by glial and immune cells are now believed to modulate neuronal transmission and promote chronic neuropathic pain. | 23136965 |
| Pneumonitis | Altered Intercellular Communication | Destructive pulmonary inflammation can leave patients with only a single functional lung, resulting in anatomical and physiological changes that may interfere with subsequent cardiac surgeries. | 23137038 |
| Inflammation, Inflammatory disorder | Altered Intercellular Communication | High-mobility group box-1 (HMGB1) is regarded as a central mediator of inflammation and involved in many inflammatory diseases. | 23137435 |
| Cessation of life, Inflammation | Altered Intercellular Communication | The p38 mitogen-activated protein kinase (MAPK) is a nexus point in inflammation, sensing, and stimulating cytokine production and driving cell migration and death. | 23137494 |
| Inflammation, Acute myocardial infarction, Atherosclerosis | Altered Intercellular Communication | The complement system is an important mediator of inflammation, which plays a pivotal role in atherosclerosis and acute myocardial infarction (AMI). | 23137511 |
| Inflammation, Hyperplasia, immunoglobulin A | Altered Intercellular Communication | Histology revealed eosinophilic inflammation with microabscesses and pseudoepitheliomatous hyperplasia, but she was negative on direct immunofluorescence for IgA, IgG and C3. | 23138121 |
| Metabolic Syndrome X, Cardiovascular Diseases, Dyslipidemias, ETV3 wt Allele, Diabetes Mellitus, Obesity, Hypertension, CTCAE | Altered Intercellular Communication | These abnormalities include obesity, dyslipidemia, hypertension, and insulin resistance and are collectively known as metabolic syndrome (MetS), a low-grade, systemic, inflammatory condition associated with an increased risk of cardiovascular disease, diabetes, and other adverse health outcomes. | 23138631 |
| Inflammation | Altered Intercellular Communication | In segments with acute inflammation, the mean MTR was slightly smaller (22.9 +- 2.2 %). | 23138635 |
| Inflammation, "Alzheimers Disease", Data types - Address | Altered Intercellular Communication | Accumulation of amyloid-b (Ab) and neurofibrillary tangles in the brain, inflammation and synaptic and neuronal loss are some of the major neuropathological hallmarks of Alzheimer's disease (AD). | 23138650 |
| Extrahepatic Cholangiocarcinoma | Altered Intercellular Communication | Inflammation-based prognostic score is a useful predictor of postoperative outcome in patients with extrahepatic cholangiocarcinoma. | 23138964 |
| Malignant Neoplasms | Altered Intercellular Communication | Recent studies have revealed that the Glasgow prognostic score (GPS), an inflammation-based prognostic score, is useful for predicting outcome in a variety of cancers. | 23138964 |
| Uremia, Inflammation, Immune System Diseases | Altered Intercellular Communication | Pathophysiologically, the immune dysfunction, telomere attrition and the presence of low-grade inflammation in uremic patients also show parallels with the aging process. | 23139404 |
| Inflammation, Hematoma, SDSL gene | Altered Intercellular Communication | A considerable body of evidence indicates that inflammation and angiogenesis play a significant role in the development and progression of chronic subdural hematoma (CSDH). | 23140147 |
| Inflammation, Hematoma, SDSL gene | Altered Intercellular Communication | Given previous evidence indicating a role for PlGF in promoting angiogenesis, inflammatory cell chemotaxis, and stimulation, as well as its ability to amplify VEGF-driven signaling under conditions favoring pathological angiogenesis, enhanced expression of PlGF in hematoma fluid suggests the involvement of this factor in the mechanisms of inflammation and angiogenesis in CSDH. | 23140147 |
| Inflammation, Malignant Neoplasms | Altered Intercellular Communication | Serum C-reactive protein (CRP) is one particular marker of systemic inflammation, and an elevated CRP level is associated with poor outcome in various malignancies. | 23141922 |
| ARCN1 gene, Chronic Obstructive Airway Disease, Pneumonitis | Altered Intercellular Communication | Chronic obstructive pulmonary disease (COPD) is characterized by pulmonary inflammation that persists after the cessation of smoking. | 23142009 |
| ARCN1 gene, Inflammation | Altered Intercellular Communication | T cells have a major role in driving inflammation in patients with COPD and are activated by specific antigens to produce mediators, such as cytokines. | 23142009 |
| ARCN1 gene, Inflammation | Altered Intercellular Communication | This proinflammatory profibrotic response might be a key cause of inflammation in patients with COPD and has implications for treatment. | 23142009 |
| Cessation of life, Inflammation, ARCN1 gene | Altered Intercellular Communication | Statins, systemic inflammation and risk of death in COPD: the Rotterdam study. | 23142156 |
| Inflammation, Acute myocardial infarction | Altered Intercellular Communication | Galectin-1 controls cardiac inflammation and ventricular remodeling during acute myocardial infarction. | 23142379 |
| Inflammation, Decreased cardiac function | Altered Intercellular Communication | Compared with their wild-type counterpart, Gal-1-deficient (Lgals1(-/-)) mice showed enhanced cardiac inflammation, characterized by increased numbers of macrophages, natural killer cells, and total T cells, but reduced frequency of regulatory T cells, leading to impaired cardiac function at baseline and impaired ventricular remodeling 7 days after nonreperfused AMI. | 23142379 |
| Inflammation | Altered Intercellular Communication | Taken together, our results indicate a protective role for Gal-1 in normal cardiac homeostasis and postinfarction remodeling by preventing cardiac inflammation. | 23142379 |
| Inflammation, Primary Biliary Cholangitis, Intrahepatic bile duct, Liver Failure, Immune-mediated | Altered Intercellular Communication | Primary biliary cirrhosis (PBC) is characterized by portal inflammation and immune-mediated destruction of intrahepatic bile ducts that often result in liver failure. | 23142582 |
| Inflammation | Altered Intercellular Communication | Tenascin-C levels in synovial fluid are elevated after injury to the human and canine joint and correlate with markers of inflammation and matrix degradation. | 23142724 |
| Inflammation, Arthropathy | Altered Intercellular Communication | The objective of the present study was to follow TN-C release into knee synovial fluid after acute joint injury or in joint disease, and to correlate TN-C levels with markers of cartilage matrix degradation and inflammation. | 23142724 |
| Inflammation, Anguilla island, Traumatic injury, Knee joint | Altered Intercellular Communication | We find highly elevated levels of TN-C in human knee joints after injury, AIA or OA that correlated with markers of cartilage degradation and inflammation. | 23142724 |
| Upgaze palsy, Parinaud Syndrome, Inflammation, Ischemia, Nystagmus, Compression | Altered Intercellular Communication | : Dorsal midbrain syndrome, which is characterized by upgaze paralysis, light-near dissociated pupils, eyelid retraction, and convergence retraction nystagmus, can be caused by compression, ischemia, inflammation, or injury to the dorsal midbrain. | 23142879 |
| Inflammation, Facial edema | Altered Intercellular Communication | Inflammation may cause facial nerve edema, and mechanical compression and ischemic change of the facial nerve may occur in the facial nerve canal. | 23143560 |
| Virus Diseases, Pneumonitis | Altered Intercellular Communication | CXCL10 may not be a bystander to the severe virus infection but may directly contribute to the pathogenesis of neutrophil-mediated, excessive pulmonary inflammation. | 23144331 |
| Pneumonitis | Altered Intercellular Communication | CXCL10-CXCR3 acts in an autocrine fashion on the oxidative burst and chemotaxis in the inflamed neutrophils, leading to fulminant pulmonary inflammation. | 23144331 |
| Airway structure, Asthma | Altered Intercellular Communication | Investigation of the association between dietary intake, disease severity and airway inflammation in asthma. | 23145908 |
| Inflammation, Asthma | Altered Intercellular Communication | Dietary intake is an important modifiable risk factor for asthma and may be related to disease severity and inflammation, through the effects of intake of anti-oxidant-rich foods and pro-inflammatory nutrients. | 23145908 |
| Airway structure, Asthma | Altered Intercellular Communication | It was found that asthmatics within the subgroup of severe persistent asthma have a different pattern of dietary intake as compared with healthy controls, which was associated with lower lung function and increased airway inflammation. | 23145908 |
| allergic inflammation | Altered Intercellular Communication | IgE is both a marker and mediator of allergic inflammation. | 23146381 |
| Inflammation, Pain Distress Question | Altered Intercellular Communication | Adverse events were found in 11.5% of the patients (inflammation and/or local pain), which were less frequent in men (8.9% versus 16.1%) and similar for both vaccines. | 23146445 |
| Inflammation, Choline Dehydrogenase, Mitochondrial | Altered Intercellular Communication | Subjects presenting lesions of endodontic origin (LEOs) or pulpal inflammation had an increased risk of developing CHD. | 23146639 |
| Palate, Swelling, Inflammation | Altered Intercellular Communication | A 43-year-old male patient presented with port wine stain on the right side of the face, the entire hard and soft palates, the alveolar ridge, and buccal mucosa, and had an excessive accumulation of calcified masses in both supragingival and subgingival sites, with swelling and generalized inflammation throughout the gingiva and alveolar mucosa. | 23147344 |
| Malignant Neoplasms | Altered Intercellular Communication | The inflammation-based Glasgow Prognostic Score (GPS) is associated with outcome in a variety of cancers. | 23147449 |
| Inflammation, hepcidin, Anemia | Altered Intercellular Communication | The complex interaction between iron stores, hepcidin, inflammation and anemia is poorly comprehended. | 23147477 |
| Inflammation, Heart failure, Anemia, hepcidin | Altered Intercellular Communication | We tested the hypothesis that, in stable heart failure patients with anemia, hepcidin is associated with iron deficiency status irrespective of inflammation. | 23147477 |
| Inflammation, Heart failure, Anemia, hepcidin | Altered Intercellular Communication | In stable heart failure patients with anemia, hepcidin levels may be more importantly regulated by patients' iron stores than by inflammation. | 23147477 |
| Amyotrophic Lateral Sclerosis, Inflammation, Abnormality of mitochondrial metabolism | Altered Intercellular Communication | Although the cause of ALS is unknown, oxidative stress, inflammation, and mitochondrial dysfunction have been identified as important components of its pathogenesis. | 23147503 |
| Inflammation, FRONTOMETAPHYSEAL DYSPLASIA 1, End Stage Liver Disease, Liver Failure | Altered Intercellular Communication | Conversely, FMD increased in parallel with Child-Pugh/Mayo Clinic Model for End-stage Liver Disease (MELD) score, bilirubin, serum sodium, plasma renin activity, leukocyte count, platelet count, and with lower arterial pressure, suggesting that enhanced FMD is a feature of advanced liver failure and inflammation. | 23147518 |
| vascular inflammations | Altered Intercellular Communication | Our study confirms the robust and widely studied role of CRP as an important marker of vascular inflammation. | 23147687 |
| Inflammation, melanoma | Altered Intercellular Communication | No active inflammation or melanoma cells were observed. | 23148706 |
| ARCN1 gene, Inflammation | Altered Intercellular Communication | An investigation of the resolution of inflammation (catabasis) in COPD. | 23148928 |
| Inflammation, Necrosis | Altered Intercellular Communication | The resolution of inflammation (catabasis) is a complex and highly regulated process where tissue resident macrophages play a key role since they phagocytose apoptotic cells (efferocytosis), preventing their secondary necrosis and the spill-over of their pro-inflammatory cytoplasmic content, and release pro-resolution and tissue repair molecules, such as TGFb, VEGF and HGF. | 23148928 |
| ARCN1 gene, Inflammation | Altered Intercellular Communication | Because inflammation does not resolve in COPD, we hypothesized that catabasis may be abnormal in these patients. | 23148928 |
| Depression, CTCAE | Altered Intercellular Communication | Although many factors may contribute to P3b amplitude differences - most notably depression and poor sleep quality, symptoms that are prevalent in the GW syndrome groups - our findings in context of previous studies on this population are consistent with the contention that dysfunction in cholinergic and dopaminergic neurotransmitter systems, and in white matter and basal ganglia may be contributing to impairments in GW veterans. | 23149040 |
| Inflammation, Pain Distress Question, Non-Small Cell Lung Carcinoma, Depressed mood, Fatigue | Altered Intercellular Communication | We applied novel statistical methods to assess whether variants of 37 inflammation genes may serve as biologic markers of risk for severe pain, depressed mood, and fatigue in non-Hispanic white patients with non-small cell lung cancer. | 23149083 |
| Inflammation, Pain Distress Question, Carcinoma of lung, Depressed mood, Fatigue | Altered Intercellular Communication | We used a generalized, multivariate, classification tree approach to explore the influence of single-nucleotide polymorphisms in the inflammation genes in pain, depressed mood, and fatigue in lung cancer patients. | 23149083 |
| Inflammation, Granulomatous inflammation | Altered Intercellular Communication | No inflammation around nerves was found in 12 specimens, abutting granulomatous inflammation was found in 1 specimen, and enveloping granulomatous inflammation was found in 1 specimen. | 23149199 |
| Necrotizing granulomatous inflammation, Leprosy, Granuloma Annulare | Altered Intercellular Communication | Perineural granulomatous inflammation resembling the perineural infiltrate of leprosy appears to be an uncommon characteristic of granuloma annulare. | 23149199 |
| Chronic lymphocytic inflammation, Vasculitis, Clippers | Altered Intercellular Communication | Atypical chronic lymphocytic inflammation with pontocerebellar perivascular enhancement responsive to steroids (CLIPPERS), primary angiitis of the CNS mimicking CLIPPERS or overlap syndrome? | 23149266 |
| Encephalomyelitis, Pontine structure, Clippers, Chronic lymphocytic inflammation | Altered Intercellular Communication | A novel type of encephalomyelitis was first described as chronic lymphocytic inflammation with pontine perivascular enhancement responsive to steroids (CLIPPERS) in 2010 and few additional patients were reported since then. | 23149266 |
| Inflammation | Altered Intercellular Communication | Influence of red pepper spice and turmeric on inflammation and oxidative stress biomarkers in overweight females: a metabolomics approach. | 23150126 |
| Inflammation, Retinitis Pigmentosa | Altered Intercellular Communication | These data indicate that 4-week supplementation with RP or TM at culinary levels does not alter oxidative stress or inflammation in overweight/obese females with systemic inflammation, or cause a significant shift in the global metabolic profile. | 23150126 |
| Inflammation, Pathologic Neovascularization, Dental Plaque | Altered Intercellular Communication | Plaque neovascularization is associated with inflammation and plaque progression. | 23150534 |
| Inflammation, Plaque, Atherosclerotic | Altered Intercellular Communication | Soluble urokinase plasminogen activator receptor is associated with inflammation in the vulnerable human atherosclerotic plaque. | 23150653 |
| Inflammation, Dental Plaque | Altered Intercellular Communication | The aim of this study was to determine whether suPAR measured in the plaque is associated with symptomatic plaques and plaque inflammation. | 23150653 |
| Inflammation, Kidney Diseases | Altered Intercellular Communication | Inflammation appears to play important roles in development and/or progression of kidney disease in AAs. | 23151275 |
| Inflammation, Fatigue | Altered Intercellular Communication | Plasma CRP and IL-6 were prospectively associated with new-onset fatigue, supporting the hypothesis that low-grade inflammation has a role in the development of fatigue. | 23151405 |
| vascular inflammations, Huntington Disease, Endothelial dysfunction | Altered Intercellular Communication | Atherogeneis is a chronic progressive syndrome caused by endothelial dysfunction, vascular inflammation, vessel wall remodeling and eventual vascular flow compromise. | 23151748 |
| Inflammation | Altered Intercellular Communication | However, information is scant on the association of chronic systemic inflammation with arterial elasticity in young asymptomatic adults. | 23151748 |
| Inflammation | Altered Intercellular Communication | These findings support the role of systemic inflammation in early pathological changes in artery wall in atherogenesis. | 23151748 |
| Inflammation, Ischemia | Altered Intercellular Communication | Chronic wounds are characterized by prolonged inflammation, bacterial bioburden, and ischemia. | 23151766 |
| Pancreatitis | Altered Intercellular Communication | USP18 is a key regulator of the interferon-driven gene network modulating pancreatic beta cell inflammation and apoptosis. | 23152055 |
| Pancreatitis | Altered Intercellular Communication | We presently analyzed the role of ubiquitin-specific peptidase 18 (USP18), an interferon-stimulated gene 15-specific protease, on IFN-induced pancreatic beta cell inflammation and apoptosis. | 23152055 |
| Inflammation | Altered Intercellular Communication | Our findings indicate that USP18 inhibition induces inflammation by increasing the STAT signaling and exacerbates IFN-induced beta cell apoptosis by the mitochondrial pathway of cell death. | 23152055 |
| Cessation of life, Inflammation | Altered Intercellular Communication | The present study shows that USP18 is a key regulator of IFN signaling in beta cells and underlines the importance of this pathway in beta cell inflammation and death. | 23152055 |
| Inflammation, Fever, CTCAE, Kidney Failure | Altered Intercellular Communication | Following treatment with a proton pump inhibitor (PPI) the patient developed fever, signs of inflammation and oliguric renal failure. | 23152072 |
| Proteinuria, Fibrosis Assessment, Interstitial inflammation, Kidney Diseases | Altered Intercellular Communication | In adriamycin-induced nephropathic mice, sEH inhibitor did not ameliorate proteinuria or level of serum albumin but reduced the long-term elevated serum creatinine level, interstitial inflammation, fibrosis, and a-SMA expression. | 23152298 |
| Chronic liver disease, Inflammation, Liver diseases | Altered Intercellular Communication | miRNAs implicated in chronic liver disease and inflammation showed expression profiles that differed from those in NL and varied among the types and grades of liver diseases. | 23152743 |
| Fibrosis, Liver, Carcinogenic Chlorinated Hydrocarbon, Hepatitis | Altered Intercellular Communication | Additionally, we could link miRNA expression pattern with liver fibrosis stage and grade of liver inflammation in CHC. | 23152743 |
| Inflammation, Hypertensive (finding) | Altered Intercellular Communication | Modest elevation in BNP in asymptomatic hypertensive patients reflects sub-clinical cardiac remodeling, inflammation and extracellular matrix changes. | 23152884 |
| Inflammation, Hypertensive (finding) | Altered Intercellular Communication | Our data provide insight into the mechanisms behind the observed negative prognostic impact of modest elevations in BNP and suggest that in an asymptomatic hypertensive cohort a peripheral BNP measurement may be a useful marker of an early, sub-clinical pathological process characterized by cardiac remodeling, inflammation and ECM alterations. | 23152884 |
| Necrotizing granulomatous inflammation, Granulomatous prostatitis | Altered Intercellular Communication | Granulomatous prostatitis, characterized by chronic granulomatous inflammation in the prostate, is rare. | 23154024 |
| Granulomatous inflammation, prostatitis | Altered Intercellular Communication | Xanthogranulomatous prostatitis is an even rarer granulomatous inflammation. | 23154024 |
| Inflammation | Altered Intercellular Communication | Echocardiogram showed no inflammation vegetation or abnormality of mechanical valve function. | 23154479 |
| Pneumonitis | Altered Intercellular Communication | On the contrary, combined administration of RT and trastuzumab is likely to induce or provoke pulmonary inflammation. | 23155270 |
| Inflammation, Osage language | Altered Intercellular Communication | The identified SNPs all lie in genes associated with inflammation suggesting inflammation may play a role in OSA pathogenesis. | 23155414 |
| Inflammation, Asthma | Altered Intercellular Communication | Salt chamber treatment is ineffective in treating eosinophilic inflammation in asthma. | 23157172 |
| Minimal Disseminated Disease, Data types - Address | Altered Intercellular Communication | Further studies on the neurotransmitter systems affected by the genetic polymorphisms found to be associated with MDD in AD may help to elucidate the underlying pathomechanisms of MDD. | 23157339 |
| Inflammation, Nasal Polyps, Chronic sinusitis, IL13 gene | Altered Intercellular Communication | Chronic rhinosinusitis with nasal polyps (NP) and allergic rhinitis (AR) is characterized by local Th2 inflammation and up-regulation of IgE; however, IgE in NP is 'polyclonal' and allergen specific, whereas IgE in AR is 'oligoclonal' and allergen specific. | 23157682 |
| Inflammation, Nasal Polyps | Altered Intercellular Communication | RAG1 and RAG2 mRNA concentrations are increased in NP and correlated with the magnitude of inflammation and the presence of S. aureus enterotoxin (superantigen)-specific IgE in the nasal polyp mucosa. | 23157682 |
| Inflammation, Rupture | Altered Intercellular Communication | C-reactive protein induces expression of matrix metalloproteinase-9: a possible link between inflammation and plaque rupture. | 23157807 |
| Inflammation, Pain Distress Question | Altered Intercellular Communication | We asked if cytokine markers of inflammation in preoperative serum or knee synovial fluid (SF) would predict pain 2 years following TKA. | 23157967 |
| Inflammation, vinyltriethoxysilane | Altered Intercellular Communication | Thus far, a causal relationship between inflammation and VTE remains to be clarified and more prospective data are required. | 23158132 |
| Inflammatory disease of mucous membrane, Irritable Bowel Syndrome | Altered Intercellular Communication | [Relationship between intestinal mucosal inflammation and mental disorders in patients with irritable bowel syndrome]. | 23158482 |
| Inflammation, Mental disorders, Irritable Bowel Syndrome, Ichthyosis Bullosa of Siemens, Comorbidity, Inflammatory disease of mucous membrane | Altered Intercellular Communication | To examine the relationship between inflammation and the comorbidity of mental disorders with irritable bowel syndrome (IBS) by comparing intestinal mucosa inflammatory biomarkers in patients with and without mental disorders. | 23158482 |
| Ichthyosis Bullosa of Siemens, Inflammatory disease of mucous membrane | Altered Intercellular Communication | Mental disorders in the IBS patients may be associated with intestinal mucosal inflammation. | 23158482 |
| Inflammation, Superior limbic keratoconjunctivitis | Altered Intercellular Communication | Superior limbic keratoconjunctivitis (SLK) is an uncommon, painful inflammation of the ocular surface localized to the superior sectors of the cornea, limbus, and conjunctiva. | 23158547 |
| Inflammation, Ischemic stroke | Altered Intercellular Communication | Association of dimethylarginines and mediators of inflammation after acute ischemic stroke. | 23158556 |
| Presenile dementia, Behavioral syndrome associated with physiological disturbance and physical factors | Altered Intercellular Communication | Several neurotransmitter systems can be linked to one specific behavioral syndrome depending on the dementia subtype. | 23159046 |
| Inflammation, Atherosclerosis | Altered Intercellular Communication | Research has indicated that inflammation promote all phases of atherosclerosis. | 23159230 |
| Inflammation | Altered Intercellular Communication | Soluble urokinase plasminogen activator receptor (suPAR) serum concentrations have recently been described to reflect the severity status of systemic inflammation. | 23159293 |
| Inflammation, Hemorrhage | Altered Intercellular Communication | The first was the severe inflammation and the second was the control of hemorrhage from GDA. | 23159354 |
| Inflammation | Altered Intercellular Communication | IOFBs may be overlooked because a small penetrating wound may be accompanied by no signs of inflammation for many decades as in this patient's clinical course. | 23159363 |
| Inflammatory abnormality of the eye, Lung Neoplasms | Altered Intercellular Communication | We report a case of ocular inflammation and lung tumors in a patient of 84 years for which the diagnosis was made through immunolabelling with IgG4 in lesions biopsied. | 23159548 |
| Pain Distress Question, Inflammation, LAURIN-SANDROW SYNDROME, Radicular pain | Altered Intercellular Communication | Symptomatic LSS patients may also suffer from radicular pain, which is a persistent pain transmitted through neural pathways, and is associated with inflammation of the exiting nerve root. | 23159960 |
| Inflammation, Disease, Diabetes Mellitus | Altered Intercellular Communication | These results further link PON1 to diabetes and inflammation and may inform the role of HDL in human disease. | 23160181 |
| Inflammation | Altered Intercellular Communication | The serotonergic system may be involved in the chronic inflammation evident in psoriatic skin. | 23161175 |
| Inflammation, Psoriasis | Altered Intercellular Communication | Through modulating the levels of SERT, there might be a therapeutic possibility for reducing chronic inflammation in psoriasis. | 23161175 |
| Inflammation, Colorectal Carcinoma | Altered Intercellular Communication | Biomarkers of inflammation are associated with colorectal cancer risk in women but are not suitable as early detection markers. | 23161620 |
| Inflammation, Colorectal Carcinoma | Altered Intercellular Communication | We here report the findings from a large prospective study with repeat measurements of CRP, as well as serum amyloid A (SAA), an additional biomarker of inflammation, and risk of CRC. | 23161620 |
| Fibrosis Assessment | Altered Intercellular Communication | Critical role of the adhesion receptor DNAX accessory molecule-1 (DNAM-1) in the development of inflammation-driven dermal fibrosis in a mouse model of systemic sclerosis. | 23161903 |
| Inflammation, Decreased cardiac function | Altered Intercellular Communication | Sickness behavior in community-dwelling elderly: associations with impaired cardiac function and inflammation. | 23162010 |
| Inflammation, Hereditary, Choline Dehydrogenase, Mitochondrial, Endothelium, Dental Plaque | Altered Intercellular Communication | (3) By BioCarta and KEGG pathway analysis, we found the target pathways of the hereditary correlated differential genes of CHD BSS with significance were mainly involved in inflammation, plaque formation, endothelial injury, and so on. | 23163136 |
| Inflammation, Hereditary, Choline Dehydrogenase, Mitochondrial, Endothelium, Dental Plaque | Altered Intercellular Communication | The hereditary correlated differential genes of CHD BSS were closely associated with inflammation, plaque formation, and endothelial injury. | 23163136 |
| Inflammation, Ulcerative Colitis | Altered Intercellular Communication | AFI could better reflect the inflammation degree of UC. | 23163137 |
| Inflammation, Metabolic Syndrome X | Altered Intercellular Communication | Metabolic syndrome and lower urinary tract symptoms: the role of inflammation. | 23165431 |
| Inflammation, ETV3 wt Allele | Altered Intercellular Communication | Chronic inflammation has been proposed as a candidate mechanism at the crossroad between these two clinical entities.Aim of study is to examine the correlation among pre-operatory LUTS/BPH severity, MetS features and inflammatory infiltrates in prostatectomy specimens. | 23165431 |
| ETV3 wt Allele, prostatitis | Altered Intercellular Communication | In conclusion, MetS can be regarded as a new determinant of prostate inflammation and BPH progression. | 23165431 |
| Inflammation, Gastritis, Atrophic | Altered Intercellular Communication | Vitamin C supplementation in relation to inflammation in individuals with atrophic gastritis: a randomised controlled trial in Japan. | 23167953 |
| Uremia, Heart failure | Altered Intercellular Communication | [Observation and multifactor analysis of refractory medium-severe heart failure by micro-inflammation modification in uremic patients]. | 23168207 |
| Uremia | Altered Intercellular Communication | Xuebijing injection can improve heart function in uremic patients by modifying micro-inflammation, whose accumulated dose and therapeutic effect show positive correlation. | 23168207 |
| Dyslipidemias | Altered Intercellular Communication | Elevated levels of intact parathyroid hormone (iPTH) may play an important role in the pathogenesis of the dyslipidemia in hemodialysis (HD) patients, but the underlying mechanisms are not clearly defined. | 23168847 |
| Atrophic, Inflammatory disease of mucous membrane | Altered Intercellular Communication | IL-1b-31C, IL-1b-511T variant alleles may accelerate gastric mucosal inflammation and atrophy, not only by themselves, but also through the interaction with co-factors. | 23169178 |
| Inflammation, Bone necrosis | Altered Intercellular Communication | These data suggest that patients with higher levels of inflammation are at an increased risk of osteonecrosis. | 23169328 |
| Inflammation, Squamous cell carcinoma, Fibrosis Assessment, Experimental Organism Basal Cell Carcinoma | Altered Intercellular Communication | The lesions were sorted into two groups: 22 squamous cell carcinomas and one basal cell carcinoma were assigned to group 1 (Marjolin ulcer), and 10 lesions of chronic ulcer with inflammation and fibrosis were assigned to group 2. | 23169733 |
| Burn Specimen Source Codes | Altered Intercellular Communication | PET/CT is useful in differentiating Marjolin ulcer from benign inflammatory conditions of chronic nonhealing ulcer in burn scars. | 23169733 |
| Inflammation, Atherosclerosis | Altered Intercellular Communication | The independent positive correlation with PAI-I indicates that oxLDL/b2GPI may serve as an early marker of low-grade inflammation and atherosclerosis initiation. | 23171597 |
| Inflammation, Fibrosis Assessment, Calcinosis | Altered Intercellular Communication | Native saphenous veins frequently showed fibrosis, but no calcification or active inflammation. | 23171851 |
| Inflammation, Fibrosis Assessment | Altered Intercellular Communication | Fibrosis can generally be regarded as an errant wound-healing process in response to chronic inflammation, and several studies have shown that the aging prostate tissue microenvironment is rich with inflammatory cells and proteins. | 23173053 |
| Inflammation, Bronchiectasis | Altered Intercellular Communication | [Non-cystic bronchiectasis: pathogenic correlations between the parameters of body composition, systemic inflammation and respiratory function]. | 23173377 |
| Inflammation, Colorectal Carcinoma | Altered Intercellular Communication | The results suggest that both MO and CRC have low-grade inflammation as part of their etiology. | 23173608 |
| Inflammation, Fibrosis Assessment, Connective Tissue Diseases, Peyronie Disease | Altered Intercellular Communication | Peyronie's disease is an acquired connective tissue disorder of the penile tunica albuginea with fibrosis and inflammation. | 23173735 |
| Hyponatremia | Altered Intercellular Communication | Severe hyponatremia caused by syndrome of inappropriate secretion of antidiuretic hormone developed as initial manifestation of human herpesvirus-6-associated acute limbic encephalitis after unrelated bone marrow transplantation. | 23173742 |
| Inflammation | Altered Intercellular Communication | Vitamin D deficiency is associated with risk for a first cardiovascular event in the general population, possibly because of inflammation, insulin resistance, and neurohumoral activation. | 23174181 |
| Inflammation, Fat-free mass, Bronchiectasis | Altered Intercellular Communication | Fat-free mass depletion and inflammation in patients with bronchiectasis. | 23174686 |
| Hyperglycemia, Dyslipidemias, Inflammation, Prediabetes syndrome | Altered Intercellular Communication | Pioglitazone slowed progression of CIMT, independent of improvement in hyperglycemia, insulin resistance, dyslipidemia, and systemic inflammation in prediabetes. | 23175674 |
| Inflammatory abnormality of the eye | Altered Intercellular Communication | Three hundred and eighty-eight patients (98.7%) presented as elective cases to the outpatient department while 5 (1.3%) presented as emergencies on account of associated ocular inflammation. | 23175879 |
| Hemorrhage, Perforation (observation), Peritonitis, Diverticulitis, Orchitis | Altered Intercellular Communication | It may be asymptomatic or complicated by diverticulitis (diverticular inflammation), bleeding, or perforation with peritonitis. | 23175883 |
| Inflammation | Altered Intercellular Communication | Changes in activities of daily living, nutrient intake, and systemic inflammation in elderly adults receiving recuperative care. | 23176675 |
| Inflammation, Macular Edema, Cystoid | Altered Intercellular Communication | Abolition of all evidence of active inflammation, visual acuity (VA), presence of cystoid macular edema at 6 months and 1 year, and adverse responses to infliximab. | 23177362 |
| Chronic disease | Altered Intercellular Communication | Inflammation markers (IM) have been associated with the development of chronic diseases. | 23177481 |
| Inflammation, Tachycardia by ECG Finding | Altered Intercellular Communication | Both elevated inflammatory activity and sustained tachycardia reflect unfavourable cardiovascular risk profiles, and there is evidence to suggest the deleterious effects of inflammation are amplified by increased heart rate. | 23178644 |
| Fibrosis Assessment, Hepatic inflammation, Hepatitis B | Altered Intercellular Communication | Influence of age and HBeAg status on the correlation between HBV DNA and hepatic inflammation and fibrosis in chronic hepatitis B patients. | 23179154 |
| Fibrosis Assessment, Hepatitis | Altered Intercellular Communication | Liver pathology was regarded as the evaluation criteria to evaluate the correlation between serum HBV DNA level and the severity of liver inflammation and fibrosis. | 23179154 |
| Fibrosis Assessment, Hepatic inflammation | Altered Intercellular Communication | Of the 215 patients, 136 were HBeAg-positive and 79 were HBeAg-negative; 134 patients had mild hepatic inflammation and fibrosis and 81 had significant hepatic inflammation and fibrosis in pathological diagnosis. | 23179154 |
| Fibrosis Assessment, Hepatic inflammation | Altered Intercellular Communication | We found that positive correlation between the severity of hepatic inflammation and fibrosis and serum HBV DNA level was only present in HBeAg-negative patients but not HBeAg-positive patients (P < 0.001). | 23179154 |
| Fibrosis Assessment, Hepatic inflammation | Altered Intercellular Communication | Patients' age was a key factor influencing the correlation between serum HBV DNA level and the severity of hepatic inflammation and fibrosis. | 23179154 |
| Fibrosis Assessment, Hepatic inflammation | Altered Intercellular Communication | the cutoff values to predict the severity of hepatic inflammation and fibrosis were 33.5 and 36 years, respectively. | 23179154 |
| Fibrosis Assessment, Hepatic inflammation | Altered Intercellular Communication | There was positive correlation between serum HBV DNA level and hepatic inflammation and fibrosis in both HBeAg-positive and HBeAg-negative patients' aged >= 35 years, but in patients aged <35 years, positive correlation was only observed in HBeAg-negative patients. | 23179154 |
| aggressive cancer, Inflammation, Prostate carcinoma, cell injury | Altered Intercellular Communication | In previous studies, we observed a positive association between Trichomonas vaginalis serostatus and risk of prostate cancer, particularly aggressive cancer, which we hypothesized might be due to T. vaginalis-mediated intraprostatic inflammation and cell damage. | 23179660 |
| Inflammation, Prostate carcinoma | Altered Intercellular Communication | Although not statistically significant, TLR4 variation appeared to influence the association between T. vaginalis serostatus and prostate cancer risk consistent with the hypothesis that inflammation plays a role in this association. | 23179660 |
| Inflammation, Chronic periaortitis, Dilatation of aorta | Altered Intercellular Communication | The larger aortic diameter in male RPF patients may be due to periaortic inflammation with resulting aortic ectasia and supports the classification of RPF into the spectrum of chronic periaortitis. | 23179671 |
| Autoimmune Diseases, Inflammation | Altered Intercellular Communication | These cytokines mediate inflammation and have been previously associated with the inflammatory process in several autoimmune diseases. | 23179933 |
| Inflammation, Chronic Kidney Diseases | Altered Intercellular Communication | Increased inflammation is common in patients with chronic kidney disease (CKD) and is associated with increased adverse cardiovascular events (CVE). | 23180042 |
| Inflammation | Altered Intercellular Communication | The downregulation of frataxin seems to be linked with uremic status, which is usually associated with chronic inflammation and the acceleration of oxidative stress. | 23180044 |
| Inflammation, Carcinogenesis | Altered Intercellular Communication | Interleukin 6 (IL6) encodes a cytokine protein, which functions in inflammation, maintains immune homeostasis and plays important roles in cervical carcinogenesis. | 23180271 |
| Hyperexplexia | Altered Intercellular Communication | To make a definite diagnosis of hyperekplexia, it may be useful to screen for genes that are involved in the glycinergic neurotransmission system. | 23182654 |
| Inflammation, Hematoma, SDSL gene | Altered Intercellular Communication | Inflammation and the coagulation system may influence the genesis of chronic subdural hematoma (CSDH). | 23183075 |
| Inflammation, Communicable Diseases, Cyst, Pseudocyst, Tissue Adhesions | Altered Intercellular Communication | Although the mechanism underlying the formation of abdominal pseudocyst remains to be clarified, several predisposing factors for cyst formation have been reported including changes in absorption of CSF due to inflammation or infection, peritoneal adhesions due to previous abdominal surgery, and increase in the protein content of the CSF. | 23183082 |
| Inflammation, Hemorrhage, idarubicin, Angiodysplasia, Crohn Disease | Altered Intercellular Communication | The small bowel diagnostic yield for IDA was 53% (n=35), including angiodysplasia 49% (n=17), nonspecific inflammation 34% (n=12), active bleeding 11% (n=4) and Crohn's disease 6% (n=2). | 23183118 |
| Inflammation, Myocardial Ischemia | Altered Intercellular Communication | Inflammation and pro- inflammatory cytokines are related to progression of IHD, but their level is seldom analyzed in association with self reported exercise tolerance. | 23183510 |
| Dyspnea, Inflammation, Myocardial Ischemia, Angina Pectoris | Altered Intercellular Communication | We have found associations of pro-inflammatory cytokines and inflammation markers with dyspnea or angina pectoris, but the relationship was not consistent in our patients with stable ischemic heart disease. | 23183510 |
| Inflammation, Ductal Carcinoma, Papilloma | Altered Intercellular Communication | Maximum and mean elasticity of invasive ductal carcinoma (IDC) were significantly higher than those of fibroadenoma (p<0.01), whereas the difference was not statistically significant with fibroadenosis, papilloma and inflammation (p>0.01). | 23184245 |
| Inflammation, Carcinogenesis | Altered Intercellular Communication | Inflammation is commonly observed in radical prostatectomy specimens, and evidence suggests that inflammation may contribute to prostate carcinogenesis. | 23184509 |
| prostatitis | Altered Intercellular Communication | Multiple microorganisms have been implicated in serving as a stimulus for prostatic inflammation. | 23184509 |
| Inflammation, Cardiovascular system | Altered Intercellular Communication | In renal patients undergoing hemodialysis, paricalcitol treatment significantly reduces oxidative stress and inflammation, two well known factors leading to cardiovascular damage. | 23186077 |
| Inflammation, Granulomatosis, Autoimmune Diseases, Granulomatosis with polyangiitis, Systemic Vasculitis | Altered Intercellular Communication | Granulomatosis with polyangiitis (GPA), also known as Wegener's granulomatosis, is an autoimmune disease characterized by inflammation of blood vessels most often seen in the upper respiratory tract, lungs, kidneys, and skin. | 23186961 |
| Intermittent | Altered Intercellular Communication | Mechanical traction induced an intermittent depression of EMG amplitudes as a sign of impaired propagation of axon potentials or synaptic transmission. | 23188536 |
| Inflammation, Plaque, Atherosclerotic | Altered Intercellular Communication | Inflammation as a systemic process plays a central role in atherosclerotic plaque progression (PP). | 23188564 |
| Extrapyramidal Disorders | Altered Intercellular Communication | There is experimental evidence that blink rate is affected in extrapyramidal disorders affecting the balance of these neurotransmitters. | 23188863 |
| Inflammation, Colitis | Altered Intercellular Communication | FXR agonists have been shown to ameliorate inflammation in murine colitis models. | 23189156 |
| Inflammation, Hematoma | Altered Intercellular Communication | The most common primary complications of surgery were hematoma and inflammation. | 23189300 |
| Hematoma | Altered Intercellular Communication | Inflammation was the most common complication associated with ramus grafts, while hematoma occurred most often in cases with chin and tuberosity grafts. | 23189300 |
| methyldopa, Inflammation | Altered Intercellular Communication | Chronic oxidative stress, inflammation and accumulation of protein-rich deposits both in the retinal pigment epithelium lysosomes and under the retinal pigment epithelium herald the onset of AMD. | 23190104 |
| Inflammation, Fibrosis Assessment, Neoplasms | Altered Intercellular Communication | Tumor detection after inflammation or fibrosis on Mohs levels. | 23190366 |
| Inflammation, Fibrosis Assessment | Altered Intercellular Communication | In Mohs micrographic surgery (MMS), many surgeons will take an additional level based solely on the presence of inflammation or fibrosis. | 23190366 |
| Inflammation, Fibrosis Assessment, Neoplasms | Altered Intercellular Communication | The surgeons reviewed their own slides in cases where tumor was detected after a level was taken for inflammation or fibrosis. | 23190366 |
| Inflammation, Fibrosis Assessment, Neoplasms | Altered Intercellular Communication | An additional level was taken for inflammation or fibrosis in 6,233 cases (27.8%), resulting in tumor detection in 121 cases (1.9%). | 23190366 |
| Inflammation, Fibrosis Assessment | Altered Intercellular Communication | Additional levels were taken for inflammation in 66.6% and fibrosis in 63.0%. | 23190366 |
| Inflammation, Neoplasms | Altered Intercellular Communication | Fourteen collision tumors were identified and were preceded by inflammation in 71% of cases. | 23190366 |
| Inflammation, Neoplasms | Altered Intercellular Communication | The presence of dense inflammation may signal an adjacent collision tumor. | 23190366 |
| Inflammation, Fibrosis Assessment, Neoplasms | Altered Intercellular Communication | Taking an additional Mohs level when dense inflammation or fibrosis is present may be warranted to ensure complete tumor removal. | 23190366 |
| Inflammation, Endothelial dysfunction | Altered Intercellular Communication | Also, elevated oxidative stress and inflammation are the main contributors of endothelial dysfunction. | 23190521 |
| Refractory anemias, Inflammation, Cardiovascular Diseases | Altered Intercellular Communication | The role of inflammation, the autonomic nervous system and classical cardiovascular disease risk factors on subendocardial viability ratio in patients with RA: a cross-sectional and longitudinal study. | 23190682 |
| Refractory anemias, Inflammation, Cyclophosphamide/Vincristine/Dacarbazine Regimen, Cardiovascular Diseases | Altered Intercellular Communication | The objective of the present study was to examine specific predictors of SEVR in RA patients, with a specific focus on inflammation and classical cardiovascular disease (CVD) risk factors. | 23190682 |
| Metabolic Diseases | Altered Intercellular Communication | As a potent antioxidant and anti-inflammation agent, kallistatin may also hold therapeutic promise in cardiometabolic disorders. | 23190873 |
| Refractory anemias, Inflammation, Rheumatoid Arthritis, Rheumatism | Altered Intercellular Communication | A decrease in high-density lipoprotein (HDL) cholesterol during inflammation is common in many rheumatologic diseases, including rheumatoid arthritis (RA). | 23190940 |
| Inflammation, Hemoglobin SS disease with crisis, Erythema Infectiosum, Infected | Altered Intercellular Communication | Given the recent reports of parvovirus B19 infection in Nigeria and the role of inflammation in sickle cell crisis, knowledge of the relationship between the two may be essential for deploying appropriate interventions in infected patients. | 23192499 |
| Inflammation, Colorectal Carcinoma | Altered Intercellular Communication | Epidemiological and experimental evidence indicates chronic inflammation as a risk factor for colorectal cancer. | 23192617 |
| Inflammation, Endothelial dysfunction | Altered Intercellular Communication | Further adjustment for markers of inflammation (c-reactive protein), endothelial dysfunction (von Willebrand factor), fibrinolytic activity (d-dimer), and g-glutamyl transferase attenuated the increased risk, but risk remained significantly increased (adjusted hazard ratios, 1.73; confidence interval, 1.06-2.83]). | 23192755 |
| Inflammation, Damage, Rheumatoid Arthritis, Disease | Altered Intercellular Communication | Positive synovial vascularity in patients with low disease activity indicates smouldering inflammation leading to joint damage in rheumatoid arthritis: time-integrated joint inflammation estimated by synovial vascularity in each finger joint. | 23192908 |
| Inflammation, Damage, Disease | Altered Intercellular Communication | Smouldering inflammation reflected by positive synovial vascularity under low disease activity was linked to joint damage. | 23192908 |
| Unknown (origin) (qualifier value), Traumatic injury, Neuropathy | Altered Intercellular Communication | trauma, compressive events, inflammations, neuropathies, or it can be idiopathic. | 23193847 |
| Gastrointestinal inflammation, Spondylitis | Altered Intercellular Communication | Markers of intestinal inflammation in patients with ankylosing spondylitis: a pilot study. | 23194008 |
| Inflammation | Altered Intercellular Communication | Further studies are needed to determine whether fCAL can be used to identify and characterize a subgroup of AS patients whose disease might be driven by subclinical bowel inflammation. | 23194008 |
| Rheumatoid Arthritis, Inflammation, Autoimmune Disorder, CTCAE, Synovitis | Altered Intercellular Communication | Rheumatoid arthritis is an autoimmune disorder characterized by persistent synovitis and systemic inflammation. | 23194101 |
| Inflammation, fibrogenesis | Altered Intercellular Communication | Galectin-3 is a new biomarker involved in inflammation and fibrogenesis and could therefore contribute to myocardial remodeling. | 23194488 |
| Inflammation, Traumatic injury | Altered Intercellular Communication | Advantages include a more precise capsulotomy and more sufficient lensectomy and anterior vitrectomy, stable intraoperative IOP, and reduced surgical trauma and inflammation. | 23195254 |
| Inflammation, Necrosis | Altered Intercellular Communication | Fibrinoid necrosis and intramural inflammation were observed in eight cases. | 23195911 |
| Inflammation, Rosacea, Edema | Altered Intercellular Communication | Phyma is the last stage of rosacea and is due to chronic inflammation and edema. | 23197212 |
| Inflammation | Altered Intercellular Communication | Prediction of early HBeAg seroconversion by decreased titers of HBeAg in the serum combined with increased grades of lobular inflammation in the liver. | 23197230 |
| Inflammation | Altered Intercellular Communication | HBeAg levels < 100 PEIU/ml combined with grades of lobular inflammation >=2 are useful for predicting early HBeAg seroconversion. | 23197230 |
| Inflammation | Altered Intercellular Communication | In patients without liver biopsies, high ALT levels (>=200 IU/L) can substitute for lobular inflammation (grades >=2). | 23197230 |
| Inflammation, Liver carcinoma, Lymphoproliferative Disorder of the Skin, Malignant Neoplasms, FAM126A gene, Cessation of life, Chronic liver disease | Altered Intercellular Communication | Nonsteroidal anti-inflammatory drugs (NSAIDs) have been shown to reduce chronic inflammation and risk of many cancers, but their effect on risk of hepatocellular carcinoma (HCC) and death due to chronic liver disease (CLD) has not been investigated. | 23197492 |
| aggressive cancer, Liver carcinoma, Hepatitis, FAM126A gene | Altered Intercellular Communication | Hepatocellular carcinoma (HCC) is a highly aggressive cancer that is linked to chronically dysregulated liver inflammation. | 23197495 |
| Conscious, Inflammation | Altered Intercellular Communication | The findings add some support to accumulating evidence for low conscientiousness being linked to higher levels of inflammation and poorer general health. | 23197841 |
| Airway structure, Gastroenteritis | Altered Intercellular Communication | Upper airway inflammation was seen in 68%, lower airway inflammation in 20% and gastroenteritis in 6%. | 23198577 |
| Airway structure | Altered Intercellular Communication | Lower airway inflammation decreased from 20% in 2009-2010 to 7% in 2010-2011. | 23198577 |
| Inflammation, Observation Method - Coagulation | Altered Intercellular Communication | Testing the hypothesis of a relationship between aspirin resistance and vascular function, inflammation and coagulation, we recruited 175 stable CAD outpatients taking 75 mg aspirin daily. | 23198725 |
| skin damage, Inflammation | Altered Intercellular Communication | In BP, there is an interplay between inflammation and coagulation both locally, which contributes to skin damage, and systemically, which leads to a prothrombotic state. | 23199326 |
| Hemorrhagic, Waldenstrom Macroglobulinemia, Neoplasm Metastasis | Altered Intercellular Communication | Histologically, primary and metastasis comprised nodules of bland ovoid cells, with primary additionally showing hemorrhagic cavities, fibrous capsule, and lymphoplasmacytic inflammation. | 23199525 |
| Airway structure, Wheezing | Altered Intercellular Communication | Assessment of airflow limitation, airway inflammation, and symptoms during virus-induced wheezing episodes in 4- to 6-year-old children. | 23199600 |
| Airway structure, Chronic Obstructive Airway Disease | Altered Intercellular Communication | We sought to prospectively assess airflow limitation and airway inflammation in children 4 to 6 years old with episodic virus-induced wheeze. | 23199600 |
| Airway structure, Chronic Obstructive Airway Disease, Wheezing | Altered Intercellular Communication | Mild episodes of wheeze in preschoolers are characterized by enhanced airway inflammation, reversible airflow limitation, and asthma-related symptoms. | 23199600 |
| Inflammation, Asthma | Altered Intercellular Communication | Longitudinal follow-up suggests that symptoms, inflammation, and lung function correlate well in this phenotype of asthma. | 23199600 |
| ARCN1 gene, Inflammation | Altered Intercellular Communication | The increased oxidative stress in patients with COPD is the result of exogenous oxidants namely pollutants and cigarette smoke as well as endogenous oxidant production during inflammation. | 23199890 |
| Inflammation, Fever, CTCAE | Altered Intercellular Communication | After the EBUS-TBNA, all cases showed prolonged fever and systemic inflammation despite receiving a sufficient dose of broad-spectrum antibiotics. | 23199981 |
| Toxic nephropathy, Hemorrhage, Ulceration, CTCAE, Duodenal inflammation | Altered Intercellular Communication | Twenty patients had treatment-related duodenal toxicity events, such as duodenal inflammation, ulceration, and bleeding. | 23200173 |
| Inflammation | Altered Intercellular Communication | In 291 patients, endomyocardial biopsies from the right ventricle were performed upon first hospital admission for assessment of cardiac inflammation. | 23200269 |
| Inflammation, Cachexia | Altered Intercellular Communication | The white adipose tissue responds to cachexia with marked local inflammation and may be thus a relevant contributor to systemic inflammation. | 23200412 |
| Inflammation, Metabolic Problems | Altered Intercellular Communication | : inflammation, weathering, and metabolic problems in late life. | 23201190 |
| Inflammation, "Alzheimers Disease", Data types - Address, Nerve Degeneration | Altered Intercellular Communication | Inflammation has been proposed as a leading force in neurodegeneration and Interleukin (IL)-18 is a pro-inflammatory cytokine which is suggested to be implicated in Alzheimer's disease (AD). | 23201485 |
| Inflammation, Hyperautofluorescent retinal lesion | Altered Intercellular Communication | Direct sun-gazing may damage the retinal structures resulting in macular inflammation and increased focal metabolism, which explains the hyperautofluorescence. | 23202400 |
| Inflammation | Altered Intercellular Communication | In summary, RIPC regulates HIF-1a levels, apoptosis and inflammation in the myocardium of cardiosurgical patients and leads to increased concentrations of circulating cytokines. | 23203207 |
| Conjunctivitis | Altered Intercellular Communication | Seven days after the operation, the fibrin glue group showed milder conjunctival inflammation than the suture group (p = 0.000). | 23204794 |
| Inflammation, Swelling | Altered Intercellular Communication | There was no evidence of inflammation or swelling within the opening. | 23204803 |
| Inflammation, Postoperative infection | Altered Intercellular Communication | Normal range of the inflammation related laboratory findings and predictors of the postoperative infection in spinal posterior fusion surgery. | 23205236 |
| Gastritis, Fibrosis Assessment, Duodenal Ulcer, Infection caused by Helicobacter pylori | Altered Intercellular Communication | Cystic fibrosis, gastroduodenal inflammation, duodenal ulcer, and H. pylori infection: the "cystic fibrosis paradox" revisited. | 23206871 |
| Inflammation, Gastric metaplasia | Altered Intercellular Communication | On duodenal histology, 94.5%, showed active inflammation and 66.7% gastric metaplasia. | 23206871 |
| Herpes Zoster Ophthalmicus | Altered Intercellular Communication | Incidence of herpes zoster ophthalmicus: results from the Pacific Ocular Inflammation Study. | 23207173 |
| Airway structure | Altered Intercellular Communication | Chronic airway inflammation is one of the proposed mechanisms to explain the formation of TO nodules. | 23207265 |
| Bronchial brand of guaifenesin-theophylline, Inflammation | Altered Intercellular Communication | The foreign body could not be identified under conventional bronchoscopy because of the presence of multiple bronchial stenoses due to chronic inflammation. | 23207364 |
| Granulomatous inflammation, Primary malignant neoplasm | Altered Intercellular Communication | Granulomatous inflammation detected by endobronchial ultrasound-guided transbronchial needle aspiration in patients with a concurrent diagnosis of cancer: a clinical conundrum. | 23207457 |
| Granulomatous inflammation | Altered Intercellular Communication | Granulomatous inflammation is occasionally identified in this setting and has unclear clinical implications. | 23207457 |
| Granulomatous inflammation, Primary malignant neoplasm | Altered Intercellular Communication | Therefore, we set out to describe a cohort of patients found to have evidence of granulomatous inflammation during EBUS-TBNA done for diagnosis and/or staging of concurrent cancer. | 23207457 |
| Communicable Diseases, Sarcoidosis, Primary malignant neoplasm, Granulomatous inflammation | Altered Intercellular Communication | Patients with evidence of granulomatous inflammation during EBUS-TBNA that was not attributable to an infectious etiology or prior sarcoidosis and a concurrent diagnosis of cancer were included. | 23207457 |
| Granulomatous inflammation, Primary malignant neoplasm | Altered Intercellular Communication | Granulomatous inflammation was identified in 154/1275 patients (12.1%), of whom 12/154 (7.8%) had a concurrent diagnosis of cancer. | 23207457 |
| Granulomatous inflammation, Malignant Neoplasms | Altered Intercellular Communication | Granulomatous inflammation is occasionally identified in mediastinal and/or hilar lymphadenopathy in patients with concurrent malignancy. | 23207457 |
| Granulomatous inflammation, Malignant Neoplasms | Altered Intercellular Communication | Although the clinical implications of this phenomenon remain to be clarified, these findings emphasize the importance of histologic confirmation of suspected lymph node involvement and suggest that the presence of granulomatous inflammation on EBUS-TBNA may occasionally be consistent with active malignancy and prompt further investigations. | 23207457 |
| Alzheimers Disease", Inflammation, Data types - Address | Altered Intercellular Communication | Alzheimer's disease (AD) has been linked to a state of cerebral and systemic inflammation. | 23207486 |
| Bronchial brand of guaifenesin-theophylline, Bronchiectasis, Airway structure | Altered Intercellular Communication | Bronchiectasis is classically defined as irreversible bronchial dilatation that represents the sequelae of chronic airway inflammation and is permanent, reflecting the presence of bronchiectasis. | 23207538 |
| Inflammation, Bulla, Erythema, Mixed Connective Tissue Disease, Toxic Epidermal Necrolysis, Adenocarcinoma of lung (disorder) | Altered Intercellular Communication | We present the case of a 58-year-old woman with history of Sharp's syndrome and adenocarcinoma of the lung, who developed toxic epidermal necrolysis after the first cycle of pemetrexed, including erythema, bullae, extensive skin denudation, subsequent systemic inflammation and severe deterioration in general condition. | 23207626 |
| Renal Insufficiency, Inflammation, Malnutrition, Anemia | Altered Intercellular Communication | The most common potential causes of anemia were inflammation, severe renal impairment, severe malnutrition, and iron deficiency; each of these causes was found in at least one-third of patients with anemia. | 23207807 |
| Inflammation, Obesity | Altered Intercellular Communication | The increased S100A9 reported for obesity and insulin resistance may be envisioned as a compensatory mechanism for inflammation. | 23207880 |
| Inflammation, Scleritis | Altered Intercellular Communication | Surgically induced necrotising scleritis (SINS) presents as a focal area of intense scleral inflammation next to the site of previous scleral or limbal excision. | 23208487 |
| Ischemia, Sensorineural Hearing Loss (disorder), Inflammation | Altered Intercellular Communication | In conclusion, HDVC may enhance hearing recovery in ISSNHL patients, which suggests that HDVC reduces levels of reactive oxygen metabolites produced by inner ear ischemia or inflammation, and that HDVC could be considered for the treatment of ISSNHL. | 23208525 |
| Inflammation, Ulcer | Altered Intercellular Communication | The ulcers heal due to the fact that the transplanted cells stimulate local regeneration processes, angiogenesis, ceased inflammation and apoptosis. | 23210179 |
| Inflammation | Altered Intercellular Communication | Reconstructive conjunctivo-sclerokeratoplasty resulted in arrest of inflammation and visual function recovery in 3 patients. | 23210346 |
| Inflammation, Anemia, Chronic disease | Altered Intercellular Communication | Once anemia is diagnosed, treatment should be based on etiology (most commonly, iron deficiency followed, in order of prevalence, by inflammation or chronic disease). | 23210492 |
| Inflammation, Periodontitis, Endothelial dysfunction | Altered Intercellular Communication | Chronic periodontitis (CP) is characterized with inflammation of the gingival tissues, which causes endothelial dysfunction in different organs. | 23211042 |
| Inflammation | Altered Intercellular Communication | Leptin plays not only an important role in regulation of food intake, but also in the mechanism of inflammation. | 23211301 |
| Inflammatory Bowel Diseases, Inflammation, Ulcerative Colitis, Dysentery | Altered Intercellular Communication | We conclude that 1) the increased leptin in exacerbated UC is related to the increased serum proinflammatory cytokines IL-1b, TNF-a and IL-6 levels; 2) In patients with infectious diarrhea, the concentrations of leptin in intestinal mucosa correlates with serum concentrations of cytokines IL-1b, IL-6 and TNF-a and with an increased expression of leptin mRNA in intestinal mucosa but not with alterations in serum levels of this hormone; 3) leptin may serve as useful predictive marker of inflammation in inflammatory bowel disease (IBD). | 23211301 |
| Inflammatory Bowel Diseases, Inflammation, Ulcerative Colitis, Dysentery | Altered Intercellular Communication | We conclude that 1) the increased leptin in exacerbated UC is related to the increased serum proinflammatory cytokines IL-1b, TNF-a and IL-6 levels; 2) In patients with infectious diarrhea, the concentrations of leptin in intestinal mucosa correlates with serum concentrations of cytokines IL-1b, IL-6 and TNF-a and with an increased expression of leptin mRNA in intestinal mucosa but not with alterations in serum levels of this hormone; 3) leptin may serve as useful predictive marker of inflammation in inflammatory bowel disease (IBD). | 23211301 |
| Inflammation, Metabolic Diseases | Altered Intercellular Communication | Recent findings have implicated the gut microbiota as a contributor of metabolic diseases through the modulation of host metabolism and inflammation. | 23212374 |
| Inflammation, Atherosclerosis | Altered Intercellular Communication | Atherosclerosis is associated with lipid accumulation and inflammation in the arterial wall, and bacteria have been suggested as a causative agent of this disease. | 23212374 |
| Inflammation, Schizophrenia | Altered Intercellular Communication | There is a growing body of evidence confirming the involvement of oxidative stress and inflammation in pathogenesis of schizophrenia. | 23212700 |
| Inflammation, Colorectal Carcinoma | Altered Intercellular Communication | Inflammation and oxidative stress play a crucial role in the development of colorectal cancer (CRC) and interference with these mechanisms represents a strategy in CRC chemoprevention. | 23213070 |
| Dermatitis | Altered Intercellular Communication | Water influences skin inflammation of the external auditory canal. | 23213950 |
| Dermatitis | Altered Intercellular Communication | Water sport players had a higher risk for ear skin inflammation than football players. | 23213950 |
| Inflammation | Altered Intercellular Communication | Nasal inverted papilloma complicated with polyps may result from long-term inflammation that occurred in the surface of the epithelia of superficial papilloma. | 23214313 |
| Hepatitis B, Acute-On-Chronic Liver Failure, CRNKL1 wt Allele | Altered Intercellular Communication | Although regulatory T cells (Treg) and interleukin-17-producing CD4 T cells (Th17) have been demonstrated to play opposing roles in inflammation-associated diseases, their frequency and balance in different stages of hepatitis B virus (HBV)-related acute-on-chronic liver failure (ACLF) remain unknown. | 23215950 |
| Inflammation, Fibrosis Assessment | Altered Intercellular Communication | The most common histopathologic finding was nonspecific inflammation with associated fibrosis. | 23217503 |
| Inflammation, Fibrosis Assessment, Lacrimal Duct Obstruction | Altered Intercellular Communication | Use of the lacrimal trephine to open canalicular obstructions provided tissue samples that revealed nonspecific inflammation and fibrosis as a common underlying histopathology. | 23217503 |
| deficiency aspects, Inflammation, Anemia | Altered Intercellular Communication | Multiple criteria models were used to determine the prevalence of Fe deficiency, anaemia and inflammation. | 23218134 |
| Inflammation, Kidney Failure, ETV3 wt Allele, Diabetes Mellitus | Altered Intercellular Communication | Multivariate analysis showed that old age, multi-vessel involvement, high levels of inflammation, diabetes and MetS were associated with 1-year composite MACE in patients with renal insufficiency. | 23218489 |
| Inflammatory abnormality of the eye | Altered Intercellular Communication | Ocular inflammation was observed in 11 patients (61%) and was severe in 1. | 23218689 |
| Inflammation, Edema | Altered Intercellular Communication | Despite inflammation in several patients, there was prolonged edema reduction and improvement in vision in several patients. | 23218689 |
| Pain Distress Question, Acute inflammation | Altered Intercellular Communication | Loteprednol etabonate gel 0.5% was efficacious and safe in treating postoperative inflammation and pain. | 23218817 |
| Communicable Diseases, Inflammation | Altered Intercellular Communication | This result supports recent findings that inflammation and infection might play an important role in the pathogenesis of ARONJ. | 23218978 |
| Inflammation, hepcidin, Anemia, Crohn Disease | Altered Intercellular Communication | Hepcidin is a key mediator of anemia of inflammation in Crohn's disease. | 23219355 |
| Inflammation, Colonization | Altered Intercellular Communication | There is evidence that chronic inflammation due to bacterial wound colonization delays wound healing. | 23220150 |
| Inflammation, Clostridium difficile infection | Altered Intercellular Communication | Besides demonstrating the increasing incidence and severity of Clostridium difficile infection, prognostic factors such as co-morbidities and laboratory parameters of inflammation were also identified. | 23220365 |
| Polymyositis, Idiopathic Inflammatory Myopathies, Myositis | Altered Intercellular Communication | Polymyositis (PM) is an idiopathic inflammatory myopathy manifested by proximal limb muscles weakness, elevated creatinin kinase, electromyography changes, and muscle inflammation in biopsy. | 23220804 |
| Inflammatory Bowel Diseases, Inflammation | Altered Intercellular Communication | The inflammation of IBD exposes plectin, stimulating a secondary immune response that may, in susceptible individuals, crossreact with the skin, provoking BP. | 23221017 |
| Cessation of life, Throat irritation, Inflammation | Altered Intercellular Communication | Chlorine is a respiratory irritant and can produce symptoms ranging from mild eye, nose, and throat irritation to severe inflammation of the lung, which can lead to death. | 23222372 |
| Sepsis, Inflammation | Altered Intercellular Communication | Obese patients had higher median C-reactive protein levels and a higher frequency of sepsis using the systemic inflammatory response syndrome criteria (72.4% versus 64.1%; p=0.03), than nonobese patients, suggesting greater systemic inflammation. | 23222873 |
| Inflammation | Altered Intercellular Communication | Contrast enhanced ultrasound (CEUS), based on the theory of inflammation and neoangiogenesis, seems to have a great potential for the detection of unstable plaques. | 23222935 |
| Inflammation, Hematoma | Altered Intercellular Communication | Nevertheless, the results of the morphological analysis demonstrate the early beginning of reparative process around the hematoma, securing the possibility of the septic inflammation. | 23222978 |
| Inflammation | Altered Intercellular Communication | The experience was successful in all cases but one, where the septic inflammation of the subcutaneous pocket developed. | 23222983 |
| Amyloidosis | Altered Intercellular Communication | Serum amyloid A (SAA) is best known for being the main component of amyloid in the inflammation-related disease amyloid A (AA) amyloidosis. | 23223242 |
| Inflammation, "Alzheimers Disease | Altered Intercellular Communication | Here we describe the role of myeloid-related protein Mrp14, a recently described amplifier of inflammation, in Alzheimer's disease and in the related amyloid precursor protein/presenilin1 (APP/PS1) mouse model. | 23223301 |
| Inflammation | Altered Intercellular Communication | Cardiometabolic profile and markers of inflammation are more severely altered in men and women with both IFG and IGT compared with those with IFG alone. | 23223343 |
| Inflammation, Anemia | Altered Intercellular Communication | Anemia and serum markers of inflammation were present in all cases. | 23223599 |
| Malignant neoplasm of urinary bladder, Inflammation, Neoplasms | Altered Intercellular Communication | Data from bladder cancer human biopsies revealed that B1 receptor expression was increased in all tumor samples and under conditions of chronic inflammation. | 23224295 |
| Granulomatous inflammation | Altered Intercellular Communication | Brimonidine-timolol fixed combination induced granulomatous inflammation of the eye. | 23224363 |
| Granulomatous inflammation | Altered Intercellular Communication | Granulomatous inflammation resolved with the cessation of antiglaucomatous drugs and topical corticosteroid treatment. | 23224363 |
| Iritis, Conjunctivitis, Hyperemia | Altered Intercellular Communication | Hyperemia may be associated with other signs such as iritis and keratic precipitates or conjunctival inflammation. | 23224363 |
| Granulomatous inflammation | Altered Intercellular Communication | In such cases, granulomatous inflammation may be considered in the differential diagnosis. | 23224363 |
| Inflammation, Squamous cell carcinoma of esophagus | Altered Intercellular Communication | The authors isolated exosomes in serum samples from patients who had ESCC and from patients who had benign diseases without systemic inflammation. | 23224754 |
| Inflammation, Squamous cell carcinoma of esophagus | Altered Intercellular Communication | The expression levels of exosomal miR-21 were significantly higher in patients with ESCC than those with benign diseases with and without (C-reactive protein <0.3 mg/dL) systemic inflammation. | 23224754 |
| Inflammation, Squamous cell carcinoma of esophagus | Altered Intercellular Communication | The current results confirmed that exosomal miR-21 expression is up-regulated in serum from patients with ESCC versus serum from patients who have benign diseases without systemic inflammation. | 23224754 |
| Intraocular inflammation, Leukemia, Myelocytic, Acute | Altered Intercellular Communication | Timely anterior chamber aspiration and subsequent cytology is useful in differentiating leukemic hypopyon from true intraocular inflammation in AML patients. | 23225088 |
| Inflammation, Heart failure, Cardiovascular system | Altered Intercellular Communication | Acute cardiovascular toxicity of sterilizers, PHMG, and PGH: severe inflammation in human cells and heart failure in zebrafish. | 23225114 |
| Cessation of life, Acute inflammation | Altered Intercellular Communication | Zebrafish embryos, which were exposed to the sterilizer, showed early death with acute inflammation and attenuated developmental speed. | 23225114 |
| Atherogenesis, Inflammation | Altered Intercellular Communication | In conclusion, the sterilizers showed acute toxic effect in blood circulation system, causing by severe inflammation, atherogenesis, and aging, with embryo toxicity. | 23225114 |
| Inflammation, Aortic valve disorder | Altered Intercellular Communication | Inflammation is associated with the remodeling of calcific aortic valve disease. | 23225202 |
| Inflammation, Heart failure | Altered Intercellular Communication | Different monocytic subsets are important in inflammation and tissue remodelling, but although heart failure (HF) is associated with local and systemic inflammation, their roles in HF are yet unknown. | 23226928 |
| ARCN1 gene, Inflammation, Chronic Obstructive Airway Disease | Altered Intercellular Communication | Haemophilus influenzae is the most common colonizing bacteria of the bronchial tree in chronic obstructive pulmonary disease (COPD), and positive cultures for this potentially pathogenic microorganism (PPM) has been associated with local inflammation changes that may influence the relationships between H. influenzae and the bronchial mucosa. | 23228114 |
| Inflammation, Electrocardiogram: myocardial infarction (finding) | Altered Intercellular Communication | The role of oxidative stress and inflammation in the early evaluation of acute non-ST-elevation myocardial infarction: an observational study. | 23228975 |
| Inflammation, Electrocardiogram: myocardial infarction (finding), Angina Pectoris | Altered Intercellular Communication | We aimed to assess the role of oxidative stress (OS) and inflammation in the early evaluation of initial acute non -ST -elevation myocardial infarction (NSTEMI) compared with unstable angina pectoris (USAP). | 23228975 |
| Inflammation, Necrotizing vasculitis, Eosinophilic disorder, Eosinophilic granulomatosis with polyangiitis, Asthma | Altered Intercellular Communication | Churg-Strauss syndrome is defined as an eosinophil-rich, granulomatous inflammation involving the respiratory tract, along with necrotizing vasculitis affecting small- to medium-sized vessels, and is associated with asthma and eosinophilia. | 23229164 |
| Skin necrosis, Inflammation | Altered Intercellular Communication | One patient developed skin necrosis at the edge of the incision in the dorsum of the foot and another whose sinus located in the toe suffered inflammation and exudation. | 23230757 |
| Acute Lung Injury, Inflammation | Altered Intercellular Communication | Recently, a new mediator of inflammation, HMGB1 protein has been identified that contributes to acute lung injury. | 23231044 |
| Renal Insufficiency, Inflammation | Altered Intercellular Communication | Inflammation appears to be associated with mineral stress even in the absence of renal dysfunction. | 23231493 |
| Oxyphilic Adenoma | Altered Intercellular Communication | Periductal inflammation/fibrosis was common in sialolipoma and oncocytic lipoadenoma. | 23232852 |
| Inflammation | Altered Intercellular Communication | Traffic pollution was related to increased inflammation for 3-, 7-, 14- and 30-day exposure periods. | 23232970 |
| Inflammation | Altered Intercellular Communication | The purpose of this investigation was to determine if the long pentraxin 3 (PTX-3) may be a useful marker of intradialytic inflammation since it is rapidly released in the vasculature. | 23235124 |
| Inflammation, Chronic Kidney Diseases | Altered Intercellular Communication | The association between nutritional status, antioxidant human paraoxonase-1 (PON1) activity and low grade inflammation in hemodialized (HD) patients with chronic kidney disease (CKD) is unclear. | 23235285 |
| Inflammation | Altered Intercellular Communication | In intraoperative findings, the tympanic segment of the fallopian canal was found to be eroded because of inflammation. | 23235551 |
| Inflammation, Glomerulonephritis | Altered Intercellular Communication | Hence, the sequela is continual glomerular deposition of complement factors with resultant inflammation and development of an 'atypical' postinfectious glomerulonephritis. | 23235567 |
| Inflammation, Fibrosis Assessment | Altered Intercellular Communication | The observed coronary LGE seems to be rather unspecific, and differentiation between coronary vessel wall fibrosis and inflammation still remains unclear. | 23236382 |
| Inflammation | Altered Intercellular Communication | Treatment was generally well tolerated, but moderately severe adverse events (i.e., body and face inflammation), were observed in four Schistosoma egg-negative children. | 23236526 |
| Inflammation, Cystadenocarcinoma, Xanthogranulomatous cholecystitis, Ulcer, Adenocarcinoma, Lobular Endocervical Glandular Hyperplasia, Adenoma | Altered Intercellular Communication | The frequency of histological lesions were as follows: acute gangrenous inflammation (8 cases, 1.5%), Rokitansky-Aschoff sinuses (RAS) (351 cases, 65%), microliths or inspissated bile in RAS (108 cases, 20%), adenomyomatous changes (16 cases, 3.0 %), focal abscess formations (12 cases, 2.2%), focal xanthogranulomatous changes (15 cases, 2.8%), mucosal ulcers (61 cases, 11.3%), cholesterosis (62 cases, 11%), cholesterol polyp (32 cases, 6%), pyloric gland metaplasia (292 cases, 54%), adenoma (7 cases, 1.3%), xanthogranulomatous cholecystitis (5 cases, 1%), invasive adenocarcinoma (12 cases, 2.2%), and cystadenocarcinoma (1 cases, 0.2%). | 23236547 |
| Inflammation, Mediastinitis | Altered Intercellular Communication | Mediastinitis after coronary artery bypass grafting (CABG) gives a longstanding chronic inflammation and has a detrimental negative effect on long-term survival. | 23237029 |
| Inflammation, Mediastinitis, Atherosclerosis | Altered Intercellular Communication | This may confirm the importance of inflammation as a major contributor to the pathogenesis of atherosclerosis and explain the negative effect of mediastinitis on a long-term survival. | 23237029 |
| Angina, Unstable | Altered Intercellular Communication | Exaggerated myocardial oxLDL amount and LOX-1 receptor over-expression associated with coronary microvessel inflammation in unstable angina. | 23237633 |
| Atherosclerosis | Altered Intercellular Communication | The purposes of this study are to investigate whether coronary microvessels are involved in coronary atherosclerosis and whether increased myocardial oxLDL amount can be associated with coronary microvessel inflammation. | 23237633 |
| Inflammation, Mitral Valve Stenosis, Angina Pectoris | Altered Intercellular Communication | A combination of immunohistochemical, RT-PCR and real-time PCR studies performed on myocardial biopsy specimens from patients with mitral stenosis (control hearts, CHs) and from unstable and stable angina patients (UAP and SAP), demonstrated that myocardial oxLDL was associated with a chronic low-grade inflammation in SAP and with a severe high grade inflammation in UAP. | 23237633 |
| Heart Diseases, Myocarditis | Altered Intercellular Communication | We report on two cases, where an endocardial and myocardial inflammation may be a relevant component of cardiac disease. | 23238003 |
| Myocarditis | Altered Intercellular Communication | Myocardial biopsy and MRI supported endocardial and myocardial inflammation. | 23238003 |
| Troponin T, Cardiac Muscle, Myocarditis | Altered Intercellular Communication | Elevated cardiac troponin T persisted in the presence of cyclophosphamide treatment, subsequent MRI suggested myocardial inflammation. | 23238003 |
| Myocarditis | Altered Intercellular Communication | We hypothesize that low-grade endocardial and myocardial inflammation may be more relevant in systemic sclerosis than appreciated previously. | 23238003 |
| Impaired cognition, Hepatitis, Visual Impairment, Congestive heart failure, Have Dizziness, Anemia, Polypharmacy, Kidney Failure | Altered Intercellular Communication | TEMs were anemia, congestive heart failure, liver inflammation, polypharmacy, renal insufficiency, cognitive impairment, dizziness, frequent mental distress, mobility difficulty, and visual impairment. | 23238312 |
| Inflammation, Waldenstrom Macroglobulinemia | Altered Intercellular Communication | The clinicopathologic study revealed intense lymphoplasmacytic and sclerosing inflammation, with IgG4-positive plasma cells and an IgG4:IgG ratio >40%. | 23238395 |
| Inflammation, Fibrosis Assessment, Atrial Fibrillation by ECG Finding | Altered Intercellular Communication | Systemic inflammation, oxidative stress, and atrial fibrosis are identified as the main mechanisms for atrial fibrillation (AF). | 23238698 |
| Inflammation | Altered Intercellular Communication | One of the most controversial issues is the role of inflammation. | 23238795 |
| Inflammation | Altered Intercellular Communication | It is well known that inflammation involves an increased expression/activity of inflammatory mediators. | 23238795 |
| Inflammation, Varicose | Altered Intercellular Communication | The aim of this study was to investigate the presence or absence of mediators of inflammation in varicose as compared to healthy veins. | 23238795 |
| Inflammation, Varicose | Altered Intercellular Communication | No difference was observed for enzymes involved in inflammation and responsible for arachidonic acid metabolism such as the acute phase reactant secreted phospholipase A2-IIA and cyclooxygenase-2, as determined in varicose and healthy veins by Western blot and real-time qRT-PCR. | 23238795 |
| Inflammation, Varicose | Altered Intercellular Communication | Our experiments demonstrate no increase in the presence of mediators of inflammation in varicose as compared to healthy veins, suggesting that inflammation may not be an important contributor to the pathogenesis of varicose veins. | 23238795 |
| Inflammation, Lymphocytic hypopituitarism | Altered Intercellular Communication | Lymphocytic hypophysitis (LYH) is a chronic inflammation that primarily affects the pituitary gland. | 23238905 |
| Inflammation, Kit Ligand, human | Altered Intercellular Communication | RDW, markers of inflammation and stem cell factor (SCF) were determined. | 23239558 |
| Inflammation, Kit Ligand, human | Altered Intercellular Communication | RDW correlated to markers of inflammation and inversely to SCF. | 23239558 |
| Inflammation, Breast Carcinoma | Altered Intercellular Communication | Research into the etiology of breast cancer has recently focused on the role of the immunity and inflammation. | 23239971 |
| Inflammation, Heart failure | Altered Intercellular Communication | Monocytes play important roles in inflammation, angiogenesis and tissue repair and may contribute to the pathophysiology of heart failure (HF). | 23240665 |
| Inflammation, Periodontitis, Osteopenia | Altered Intercellular Communication | Subjects were classified as follows: 1) healthy subjects with no attachment loss >1mm and no clinical signs of gingival or periodontal inflammation; 2) diseased subjects with mild periodontitis (less than 15%0 of global periodontal bone loss); 3) subjects with moderate periodontitis (less than 4 interproximal sites with bone loss = or >50 percent and mean bone loss between 15 and 30%); 4) subjects with severe periodontitis (more than 7 interproximal sites with >50% bone loss and mean bone loss >35%0). | 23241110 |
| Inflammation | Altered Intercellular Communication | A 69-year-old fisherman underwent laparoscopic cholecystectomy due to severe inflammation in the gallbladder. | 23241376 |
| Inflammation, Hypoxia-Ischemia, Brain, Hyperoxia | Altered Intercellular Communication | Hyperoxic resuscitation after hypoxia-ischemia induces cerebral inflammation that is attenuated by tempol in a reporter mouse model with very young mice. | 23241583 |
| Tissue damage, Inflammation | Altered Intercellular Communication | Mechanisms for tissue damage by hypoxia/ischemia in the extreme premature involve inflammation. | 23241583 |
| Inflammation, Brain Injuries | Altered Intercellular Communication | Tempol treatment attenuated inflammation but did not reduce the extent of histological cerebral damage. | 23241583 |
| Inflammation | Altered Intercellular Communication | Epigenetic modification, oxidative stress, and inflammation play an important role in the pathogenesis of the disease. | 23242124 |
| Inflammation, Impaired cognition, MS gene, Disability, Axon loss | Altered Intercellular Communication | Gray matter lesions are thought to play a key role in the progression of disability and cognitive impairment in multiple sclerosis (MS) patients, but whether gray matter damage is caused by inflammation or secondary to axon loss in the white matter, or both, is not clear. | 23242282 |
| Meningitis | Altered Intercellular Communication | In an analysis of postmortem brain samples from 44 cases of secondary progressive MS, 26 cases were characterized by meningeal inflammation with ectopic B-cell follicles and prominent gray matter pathology; subpial cortical lesions containing dense perivascular lymphocytic infiltrates were present in 11 of these cases. | 23242282 |
| Inflammation, Damage, White matter lesions | Altered Intercellular Communication | These findings indicate that both meningeal and intraparenchymal inflammation may contribute to cortical damage during MS progression, and that intracortical inflammation may be sustained by an EBV-driven immunopathologic response, similar to findings in white matter lesions and meninges. | 23242282 |
| Graves Disease, Chronic inflammation, Endothelial dysfunction | Altered Intercellular Communication | The etiopathogenesis of Graves' disease (GD) has not been clearly elucidated although the role of chronical inflammation and endothelial dysfunction has been established. | 23242661 |
| Inflammation, herpesvirus 3, human | Altered Intercellular Communication | Late VZV vasculopathy is distinguished by viral antigen without inflammation in media, revealing a human virus in an immunoprivileged arterial media. | 23243076 |
| Inflammation, herpesvirus 3, human | Altered Intercellular Communication | Association of thickened intima and inflammation in vaso vasorum vessels in early VZV vasculopathy support the role of virus-induced inflammation in vessel wall remodeling. | 23243076 |
| Inflammation, Pancreatic carcinoma | Altered Intercellular Communication | Although development of pancreatic cancer is associated with states of insulin resistance and chronic inflammation, the mechanistic basis of the associations is poorly understood. | 23243202 |
| Refractory anemias, Inflammation | Altered Intercellular Communication | The influence of inflammation on the myocardium in RA needs further studies. | 23244227 |
| Inflammation, MS gene | Altered Intercellular Communication | We hypothesized that due to chronic inflammation, MS patients would present with a higher levels of cardiovascular (CV) risk factors than non-MS patients. | 23244431 |
| Inflammation, Fibrous | Altered Intercellular Communication | The pathophysiology of this phenomenon remains unclear but could be related to chronic inflammation with development of a fibrous layer along the visceral pleura. | 23244504 |
| Inflammation, Malnutrition | Altered Intercellular Communication | Malnutrition and chronic inflammation in dialysis patients negatively impact their survival prognosis, and nutrients, such as omega-3 oils, are postulated to reduce proinflammatory response. | 23244537 |
| Inflammation, Atherosclerotic lesion | Altered Intercellular Communication | Pentraxin3 (PTX3), a recently discovered inflammatory mediator, is produced abundantly in various cells in atherosclerotic lesions, and therefore, its plasma level could reflect local inflammation at the site of atherosclerotic lesion. | 23245734 |
| Dermatitis, Mental disorders, Data types - Address | Altered Intercellular Communication | Strategies to prevent AD or to aggressively treat early skin inflammation might modify the risk of mental health disorders in at-risk children. | 23245818 |
| vascular inflammations, Cyclophosphamide/Vincristine/Dacarbazine Regimen, Cardiovascular Diseases | Altered Intercellular Communication | Children's early development of cardiovascular disease (CVD) risk factors may include exposure to key biological components responsible for vascular inflammation in young adults. | 23246302 |
| Orbital Pseudotumor | Altered Intercellular Communication | Atypical idiopathic orbital inflammation in a young girl. | 23247034 |
| Orbital Pseudotumor | Altered Intercellular Communication | After a negative workup, she was diagnosed and treated for idiopathic orbital inflammation (IOI) with a brisk response to oral steroids. | 23247034 |
| Inflammation, Leukocytes | Altered Intercellular Communication | Blood data representing inflammation (WBC and CRP) showed marked differences, especially on postoperative day 7 (P = 0.0016 and P = 0.0061, respectively). | 23247737 |
| Cervical Soft Tissue Neoplasm, Inflammation, Necrotizing fasciitis | Altered Intercellular Communication | Necrotizing fasciitis is a potentially life-threatening complication of severe cervical soft tissue inflammation. | 23247748 |
| Cystic medial necrosis of aorta, Inflammation, Fibrosis Assessment | Altered Intercellular Communication | In contrast, TAV-associated ascending aortas were characterized by a significant severity of elastic fragmentation, cystic medial necrosis, medial fibrosis and inflammation. | 23248206 |
| Inflammation, Hypertension, CTCAE | Altered Intercellular Communication | They, combined with hypertension and age, significantly increase both the microscopic lesions and inflammation. | 23248206 |
| Seizures, Torticollis, Meningitis | Altered Intercellular Communication | Presentation with torticollis and simple partial seizures resulting from diffuse leptomeningeal inflammation is rare. | 23249509 |
| Seizures, Inflammation, neuroborreliosis, Torticollis | Altered Intercellular Communication | As illustrated by this case neuroborreliosis can manifest itself atypically with torticollis, seizures and diffuse leptomeningeal enhancement due to inflammation. | 23249509 |
| Inflammation | Altered Intercellular Communication | Neutrophil-to-lymphocyte ratio (NLR) is a novel inflammation index that has been shown to independently predict poor clinical outcomes. | 23249602 |
| Inflammation, Angina Pectoris, Variant | Altered Intercellular Communication | Aerobic interval exercise training in the afternoon reduces attacks of coronary spastic angina in conjunction with improvement in endothelial function, oxidative stress, and inflammation. | 23249633 |
| Inflammation, SLC5A8 wt Allele, Angina Pectoris, Variant | Altered Intercellular Communication | AIT in the afternoon suppressed the attacks in conjunction with improvement in endothelial function, oxidative stress, inflammation, and insulin resistance in patients with coronary spastic angina. | 23249633 |
| Inflammation, EVP-0015962, Dental Plaque, Memory impairment | Altered Intercellular Communication | Chronic treatment with EVP-0015962 was well tolerated in mice and lowered the production of Ab42, attenuated memory deficits, and reduced Ab plaque formation and inflammation in Tg2576 transgenic animals. | 23249765 |
| Inflammation, Muscle (organ) | Altered Intercellular Communication | Muscle lesions and inflammation in futsal players according to their tactical positions. | 23249823 |
| Inflammation, Muscle (organ) | Altered Intercellular Communication | Thus, the purpose of this study was to characterize muscle lesion and inflammation in futsal players according to their positions in an official match. | 23249823 |
| Inflammation, Muscle damage | Altered Intercellular Communication | Goalkeepers showed higher LDH and IL-6 than players occupying other tactical positions, leading to the conclusion that the tactical position of futsal goalkeeper causes more inflammation and muscle damage than other positions. | 23249823 |
| Uterine Cervical Neoplasm, Inflammation | Altered Intercellular Communication | [The prevalence of abnormal cytology and inflammation and their association with risk factors for uterine cervical neoplasms in Cauca, Colombia]. | 23250315 |
| Uterine Cervical Neoplasm, Inflammation | Altered Intercellular Communication | Establishing the prevalence of abnormal and inflammation cytology reports and its association with risks factors for uterine cervical neoplasms amongst females from the Cauca department in Colombia. | 23250315 |
| Lymphoid nodule, Fibrous, Inflammation | Altered Intercellular Communication | Histological examination of the implant revealed degradation on the medial side of the implant while the mass consisted of fibrous tissue with chronic inflammation and lymphoid follicle formation around a foreign material. | 23250330 |
| Inflammation, Abscess | Altered Intercellular Communication | Forms 3 and 4 of this pathology manifest themselves in the early childhood; they are frequently associated with inflammation and recurrence as well as the development of abscesses. | 23250530 |
| Suppuration, Inflammation | Altered Intercellular Communication | It was shown that only the complete removal of congenital parotid fistula prevents its inflammation and suppuration. | 23250530 |
| Inflammation, OSTF1 gene, Fibrosis Assessment | Altered Intercellular Communication | Oral submucous fibrosis (OSF) is a precancerous condition of oral mucosa with inflammation and progressive fibrosis of the lamina propria and deeper connective tissue. | 23250779 |
| Inflammation | Altered Intercellular Communication | The hypermethylation of E-cadherin and cyclooxygenase 2 (COX-2) in chronic inflammation may demonstrate a mild lesion/mutation at epigenetic levels. | 23250779 |
| Inflammation, Primary malignant neoplasm | Altered Intercellular Communication | The epigenetic changes presented in patients with chronic inflammation might demonstrate an irreversible destruction in the tissues or organs similar to the effects of cancer. | 23250779 |
| Inflammation, Neoplasms | Altered Intercellular Communication | A proinflammatory cytokine, interleukin 23 (IL-23), plays a role in tumor progression by inducing inflammation in the tumor microenvironment, although there is debate about its role in carcinogenesis. | 23250909 |
| Inflammation, Heart failure, Endothelial dysfunction | Altered Intercellular Communication | Resting heart rate and incident heart failure and cardiovascular mortality in older adults: role of inflammation and endothelial dysfunction: the PROSPER study. | 23250912 |
| Inflammation, Endothelial dysfunction | Altered Intercellular Communication | Increased heart rate is associated with increased systemic inflammation and endothelial dysfunction. | 23250912 |
| Inflammation, Gastritis, Atrophic | Altered Intercellular Communication | On the basis of the histological diagnosis, PCA-positive patients were divided into 4 groups: (1) 30 patients with chronic atrophic gastritis; they had high concentrations of PCA and gastrin and no detectable IFA; (2) 14 subjects with metaplastic gastric atrophy; they had high PCA, IFA, and gastrin; (3) 18 patients with nonspecific lymphocytic inflammation with increased PCA, normal gastrin levels, and absence of IFA; (4) 21 patients with multifocal atrophic gastritis with "borderline" PCA, normal gastrin, absence of IFA and presence of anti-Hp in 100% of the cases. | 23251219 |
| Communicable Diseases, Pleural Diseases, Inflammation | Altered Intercellular Communication | Ability of procalcitonin to discriminate infection from non-infective inflammation using two pleural disease settings. | 23251353 |
| Communicable Diseases, Inflammation | Altered Intercellular Communication | However, infection is often paralleled by tissue inflammation. | 23251353 |
| Pleurisy, effusion | Altered Intercellular Communication | Pleurodesis, often used to treat effusions, involves provocation of intense aseptic pleural inflammation. | 23251353 |
| Inflammation, Pleural Infection | Altered Intercellular Communication | 1) Procalcitonin was significantly higher in patients with pleural infection compared with controls with non-infective effusions (n = 32 each group) that were case-matched for systemic inflammation as measured by CRP [median (25-75%IQR): 0.58 (0.35-1.50) vs 0.34 (0.31-0.42) ug/L respectively, p = 0.003]. | 23251353 |
| Inflammation, talc | Altered Intercellular Communication | 2) Talc pleurodesis provoked intense systemic inflammation, and raised serum CRP by 360% over baseline. | 23251353 |
| Communicable Diseases, Pleural Diseases, Inflammation | Altered Intercellular Communication | Procalcitonin is superior to CRP in distinguishing infection from non-infective pleural diseases, even when controlled for the level of systemic inflammation. | 23251353 |
| Acute Lung Injury, Inflammation | Altered Intercellular Communication | Inflammation and immune-related candidate gene associations with acute lung injury susceptibility and severity: a validation study. | 23251429 |
| Acute Lung Injury, Inflammation | Altered Intercellular Communication | Common variants in genes related to inflammation, innate immunity, epithelial cell function, and angiogenesis have been reported to be associated with risks for Acute Lung Injury (ALI) and related outcomes. | 23251429 |
| Acute Lung Injury, Inflammation | Altered Intercellular Communication | These associations provide further evidence that genetic factors in genes related to immunity and inflammation contribute to ALI pathogenesis. | 23251429 |
| Inflammation, Mental deterioration, Obesity, Abdominal, Impaired cognition | Altered Intercellular Communication | We investigated the relation between cognitive impairment and metabolic deteriorations, low physical fitness, low-grade inflammation and abdominal obesity in middle aged individuals. | 23251434 |
| Inflammation, Obesity | Altered Intercellular Communication | Measurements of blood glucose, obesity and inflammation were not associated with cognitive function. | 23251434 |
| Inflammation, Atherosclerosis, Immune System Diseases, HIV Infections | Altered Intercellular Communication | HIV infection is associated with an increased risk of age-related morbidity mediated by immune dysfunction, atherosclerosis and inflammation. | 23251521 |
| Eye, Infiltration, Inflammation | Altered Intercellular Communication | Multifocal intrastromal infiltration, with relatively quiet ocular reaction and mild inflammation were initially presented in all eyes. | 23252209 |
| Neoplasms, Chronic sclerosing sialadenitis | Altered Intercellular Communication | Kuttner tumor or chronic sclerosing sialadenitis is a benign inflammatory condition of the salivary gland. | 23253027 |
| Inflammation, Cerebrovascular accident | Altered Intercellular Communication | Inflammation plays a crucial role in the pathogenesis and prognosis of stroke. | 23253530 |
| Inflammation | Altered Intercellular Communication | Relative to plain images, the high negative per cent agreement for normal glands suggests that, if an abnormal finding is detected on CBCT images, then disease can be ruled in, and the high positive per cent agreement for glands with inflammatory changes suggests that inflammation can be ruled out if these changes are not seen on CBCT images. | 23253564 |
| Inflammation, Neoplasms | Altered Intercellular Communication | Nevertheless, this interesting hypothesis and the role of inflammation in tumor biology remain complex and incompletely sure. | 23254959 |
| Rheumatoid Arthritis, Osteitis, Synovitis | Altered Intercellular Communication | Synovitis and bone inflammation in early rheumatoid arthritis: high-resolution multi-pinhole SPECT versus MRI. | 23255070 |
| Rheumatoid Arthritis, Osteitis, Synovitis | Altered Intercellular Communication | We aimed to assess the relationship between bone inflammation in multi-pinhole single-photon emission computed tomography (MPH-SPECT) and synovitis detected by magnetic resonance imaging (MRI) in early rheumatoid arthritis patients. | 23255070 |
| Inflammation, Rheumatoid Arthritis | Altered Intercellular Communication | Presence of joint inflammation in MRI was investigated using the subscores of the rheumatoid arthritis MRI score. | 23255070 |
| Depressive disorder | Altered Intercellular Communication | One carbon metabolism in the CNS plays a critical role in the synthesis and release of neurotransmitters which are relevant to depressive disorder. | 23255668 |
| Inflammation, Neuromyelitis Optica | Altered Intercellular Communication | CSF high-mobility group box 1 is associated with intrathecal inflammation and astrocytic damage in neuromyelitis optica. | 23255728 |
| Inflammation, N-nitrosomorpholine | Altered Intercellular Communication | HMGB1 could play a key role in central nervous system inflammation in NMO patients. | 23255728 |
| Vasculitis, Leukocytoclastic, Cutaneous, Inflammation, Purpura | Altered Intercellular Communication | Leukocytoclastic vasculitis (LCV) usually presents palpable purpura characterized by inflammation of vessel walls and fragmentation of nuclei. | 23255867 |
| Acute and chronic inflammation | Altered Intercellular Communication | While traditional cardiovascular risk factors and the effects of HIV and chronic inflammation all play a role, the contribution of long-term exposure to antiretroviral (ARV) agents is becoming clear. | 23256968 |
| Inflammation, Sleep Apnea, Obstructive, Airway Obstruction, Enlargement of tonsil or adenoid | Altered Intercellular Communication | We identified more severe obstructive sleep apnoea in clinically referred children during winter and spring and suggest that inflammation from respiratory viruses may contribute to adenotonsillar hypertrophy, worsening airway obstruction. | 23257064 |
| Airway structure, ARCN1 gene | Altered Intercellular Communication | Inhaled pan-selectin antagonist Bimosiamose attenuates airway inflammation in COPD. | 23257347 |
| Airway structure | Altered Intercellular Communication | It led to an attenuation of airway inflammation (EudraCT 2009-017257-35; NCT ID: NCT01108913). | 23257347 |
| Inflammation, Benign prostatic hypertrophy, Obesity | Altered Intercellular Communication | Inflammation is postulated to link obesity and benign prostatic hyperplasia (BPH). | 23257365 |
| Inflammation, Mucosa-Associated Lymphoid Tissue Lymphoma | Altered Intercellular Communication | The association of chronic inflammation with the development of MALT lymphomas has been widely accepted. | 23257674 |
| Inflammation, PDR gene, Vitreous strands | Altered Intercellular Communication | The elevated IL-6 and IL-8 levels in vitreous, but not in plasma, are evidence favouring local over systemic inflammation in PDR. | 23257933 |
| Inflammation | Altered Intercellular Communication | Increased apoptosis along with enhanced inflammation has been reported in hemodialysis and pre-dialysis patients. | 23258075 |
| Tumor necrosis, Inflammation | Altered Intercellular Communication | Serum levels of C-reactive protein, tumor necrosis factor-a (TNF-a), interleukin-6 and plasma levels of fibrinogen were measured as markers of inflammation. | 23258075 |
| Inflammation, PBK gene, Keratopathy | Altered Intercellular Communication | According to some studies, inflammation is a potential etiological factor in pseudophakic bullous keratopathy (PBK). | 23258303 |
| Inflammation, Gout | Altered Intercellular Communication | Acute gout is associated with a decrease in serum uric acid (SUA) that is considered to be in response to acute inflammation but it may be a feature of gout itself. | 23258648 |
| Inflammation | Altered Intercellular Communication | Histology showed that there was prominent histiocytic inflammation with granular acellular eosinophilic components. | 23259725 |
| Inflammation | Altered Intercellular Communication | Interestingly, out of the 26 patients with fibrotic changes, 22 (85%) had positive pulmonary PET findings, of whom 18/22 (82%) showed extrathoracic PET-positive lesions and 16/22 (73%) showed signs of serological inflammation. | 23261309 |
| Tissue Adhesions, Inflammation, Hemorrhage, Respiration Disorders, Injury of bile duct | Altered Intercellular Communication | The reasons for the conversion consisted of adhesions (15 cases), inflammation (8 cases), adhesion plus inflammation (9 cases), bleeding (8 cases), common bile duct injury (4 cases), suspected common bile duct injury (1 case), injury of the duodenal bulb (1 case) and respiratory disorder (1 case). | 23263446 |
| Cataract, Pain Distress Question, Inflammation | Altered Intercellular Communication | It typically presents within 24 h of uncomplicated cataract surgery with minimal or no pain and intense anterior segment inflammation (Monson et al. | 23263731 |
| vascular inflammations, Calcinosis | Altered Intercellular Communication | Our data demonstrated the longitudinal progressions of vascular inflammation and calcification of health-screening subjects. | 23264081 |
| Inflammation, Calcinosis | Altered Intercellular Communication | Inflammation and calcification were observed to progress significantly faster in the abdominal aorta than in the thoracic aorta. | 23264081 |
| vascular inflammations, Calcinosis | Altered Intercellular Communication | The progressions of vascular inflammation and calcification may be associated with different atherogenic risk factors. | 23264081 |
| Inflammation, Aneurysm, Ruptured | Altered Intercellular Communication | Assessment of the inflammation and neovascularization in the wall and thrombus of the AAA might be an important factor in monitoring the progression and the risk of aneurysm's rupture. | 23264218 |
| Inflammation | Altered Intercellular Communication | One of the essential changes in inflammation is adhesion of leukocyte to endothelium and transmigration of leukocytes to the sites of inflammation. | 23264403 |
| Cholangitis | Altered Intercellular Communication | Histological re-examination identified immunoglobulin G4-related sclerosing cholangitis (n = 2) and nonspecific fibrosis/inflammation (n = 3). | 23265129 |
| Inflammation, Tissue Adhesions | Altered Intercellular Communication | However, inflammation, adhesions, and anatomic difficulty continue to challenge the use and safety of this approach in a small number of patients. | 23265130 |
| Inflammation, Rupture | Altered Intercellular Communication | Histologically unstable asymptomatic carotid plaques have altered expression of genes involved in chemokine signalling leading to localised plaque inflammation and rupture. | 23265682 |
| Degenerative polyarthritis, Inflammation, Obesity | Altered Intercellular Communication | Obesity is associated with osteoarthritis and it is accompanied by chronic inflammation and elevated oxidative stress. | 23266138 |
| Inflammation, Pain Distress Question, Osteoarthritis, Knee | Altered Intercellular Communication | Isokinetic exercise produces minimal inflammation and pain in knee osteoarthritis patients, could be performed every 48h during rehabilitation, and up-regulates patients' antioxidant system. | 23266138 |
| Inflammation, Congenital arteriovenous malformation | Altered Intercellular Communication | Microvascular proliferations in arteriovenous malformations relate to high-flow characteristics, inflammation, and previous therapeutic embolization of the lesion. | 23266341 |
| Inflammation, Thrombosis | Altered Intercellular Communication | Resection specimens of 80 AVMs were clinically categorized as either high- or low-flow lesions, and histopathologically screened for the presence of microvessels, inflammation, thrombosis, or a combination of these. | 23266341 |
| Inflammation, Thrombosis | Altered Intercellular Communication | In high-flow lesions, which were embolized before surgery (30% of all), 88% showed microvascular proliferation, 88% inflammation, and 33% thrombosis. | 23266341 |
| Inflammation, Depression, CTCAE | Altered Intercellular Communication | CONTEXT The pathogenesis of depression is not fully understood, but studies suggest that low-grade systemic inflammation contributes to the development of depression. | 23266538 |
| malignant disease, Inflammation | Altered Intercellular Communication | MDSCs seem to play an important role in inflammation that is strongly related to advancing malignant diseases. | 23267986 |
| Inflammation | Altered Intercellular Communication | [The treatment of the patients presenting with chronic inflammation of the trepanation cavity with a preparation containing silver nanoparticles following sanitation surgery of the open type]. | 23268263 |
| Inflammation, Malignant Neoplasms, Goblet cell of small intestine | Altered Intercellular Communication | A background of chronic inflammation increases the frequency of expression of an intestinal goblet-cell phenotype and p53 in the cancers. | 23268317 |
| Inflammation, Anemia, Chronic Kidney Diseases | Altered Intercellular Communication | Our results demonstrated that the cause of anemia was iron deficiency, chronic inflammation, or chronic kidney disease in 75% of the patients, and that anemia was improved in more than 80% of the patients after appropriate therapeutic treatment. | 23268911 |
| Granulomatous inflammation | Altered Intercellular Communication | The tonsils are uncommonly affected by granulomatous inflammation. | 23269077 |
| Necrotizing granulomatous inflammation | Altered Intercellular Communication | This study attempted to clarify the clinicopathological and immunohistochemical findings and presence or absence of Epstein-Barr virus (EBV) in tonsilar granulomatous inflammation. | 23269077 |
| Idiopathic Inflammatory Myopathies, Inflammation, Paresis, Myopathy | Altered Intercellular Communication | The idiopathic inflammatory myopathies (IIM) are acquired muscle diseases characterized by muscle weakness and inflammation on muscle biopsy. | 23269233 |
| Inflammation, Acute inflammation | Altered Intercellular Communication | A total of 82 % of patients had chronic low-grade inflammation of the gallbladder wall and 18.0 % had acute inflammatory exacerbations. | 23270822 |
| Inflammation | Altered Intercellular Communication | From our study, we found chronic and/or intermittent cystic duct obstructions and low-grade GB wall inflammation lead to GB epithelium hydrogen secretion dysfunction. | 23270822 |
| Inflammation, Hemorrhage, Dental Plaque, Rupture | Altered Intercellular Communication | Seven histological features of plaque instability (haemorrhage, large lipid core, chronic plaque inflammation, chronic cap inflammation, marked vascularity, cap rupture and many foam cells) were independently quantified and then correlated with recency of symptoms in patients undergoing CEA. | 23270859 |
| Inflammation, Hemorrhage, Rupture | Altered Intercellular Communication | However, there was then a marked increase in the prevalence of plaque haemorrhage (59% up to 65%), large lipid core (41% up to 78%), chronic plaque inflammation (71% up to 91%), cap rupture (35% up to 39%), many foam cells (24% up to 43%) and marked vascularity (71% up to 91%) in 23 patients undergoing CEA after 29 days had elapsed. | 23270859 |
| Inflammation, Corneal edema | Altered Intercellular Communication | In all patients, active inflammation and corneal edema resolved within 6 weeks, and visual outcome was 20/20. | 23271338 |
| Inflammation, Sacroiliac joint structure, Peripheral, Spondylitis | Altered Intercellular Communication | Ankylosing spondylitis (AS) is a chronic inflammation of the sacroiliac joints, spine and peripheral joints. | 23272049 |
| Inflammation, "Alzheimers Disease", Data types - Address | Altered Intercellular Communication | Toll like receptor 4 (TLR4) has been related to inflammation and beta-amyloid deposition in Alzheimer's disease (AD) brain. | 23272070 |
| Inflammation, Prostate carcinoma | Altered Intercellular Communication | Association of the innate immunity and inflammation pathway with advanced prostate cancer risk. | 23272139 |
| Inflammation, Prostate carcinoma | Altered Intercellular Communication | Innate immunity and inflammation may increase the risk of prostate cancer. | 23272139 |
| Inflammation, Prostate carcinoma | Altered Intercellular Communication | Our results suggest that the innate immunity and inflammation pathway may play a modest role in the etiology of advanced prostate cancer through multiple small effects. | 23272139 |
| Chronic infectious disease, Inflammation | Altered Intercellular Communication | Chronic infection may induce persistent inflammation of the tissue and secondarily, a cancerization process within a few years. | 23272143 |
| Inflammation | Altered Intercellular Communication | Eosinophils (Eo) are one type of the major proinflammatory cells of the chronic inflammation in the intestine. | 23272174 |
| Eosinophilic disorder, Inflammation, Fibrillary glomerulonephritis | Altered Intercellular Communication | After treatment with FGN intrarectally, mice with eosinophilia showed severe inflammation in the colon. | 23272174 |
| Gastrointestinal inflammation | Altered Intercellular Communication | The interaction of galectin 3 and CD98 can induce Eos to release chemical mediators that contributes to the initiation of the intestinal inflammation. | 23272174 |
| Necrotizing enterocolitis in fetus OR newborn, Gastrointestinal inflammation | Altered Intercellular Communication | Multiple pro- and anti-inflammatory cytokines have been identified as markers of intestinal inflammation, both in human patients with NEC and in models of immature intestine. | 23272193 |
| Inflammation, Dysbiosis, Necrotizing enterocolitis in fetus OR newborn | Altered Intercellular Communication | Specifically, IL-10 signaling attenuates intestinal responses to gut dysbiosis, and disruption of this pathway exacerbates inflammation in murine models of NEC. | 23272193 |
| Vascular insufficiency of intestine, Inflammation, Fibrosis Assessment | Altered Intercellular Communication | We have developed an accurate bioassay utilizing proteins representing four central pathogenetic modalities of the disease: lymphangiogenesis, inflammation, fibrosis, and lipid metabolism, suggesting that these proteins are directly related to the pathogenesis of the tissue pathology in lymphatic vascular insufficiency. | 23272198 |
| Inflammation, AHSG protein, human | Altered Intercellular Communication | Fetuin-A is a liver protein that may serve as an inhibitor of systemic inflammation in humans. | 23272665 |
| Inflammation, doxorubicin/procarbazine/vincristine protocol | Altered Intercellular Communication | PTX3 was not superior to CRP as a biomarker to diagnose VAP, but it was an early indicator of inflammation and had better prognostic value to predict mortality than CRP. | 23273657 |
| doxorubicin/procarbazine/vincristine protocol | Altered Intercellular Communication | The PTX3 values increase rapidly during multiple inflammatory conditions, but little is known about its characteristics in VAP. | 23273657 |
| Inflammation, Ischemic stroke, atherosclerotic | Altered Intercellular Communication | Our data show that M1 macrophage content of atherosclerotic plaques is associated with clinical incidence of ischemic stroke and increased inflammation or fibrinolysis. | 23273713 |
| Compartment syndromes, Inflammation, Myositis, CTCAE 5.0 | Altered Intercellular Communication | The severity of the inflammation resulted in a forearm myositis secondarily causing a compartment syndrome that was treated with several prolonged courses of corticosteroids. | 23274380 |
| Alzheimers Disease", Data types - Address | Altered Intercellular Communication | Genetic variants of the serotonergic neurotransmitter system are potential contributing factors in the pathological processes underlying Alzheimer's disease (AD). | 23274704 |
| Granulomatous inflammation, Enteritis, Crohn Disease | Altered Intercellular Communication | Colonoscopy showed active enteritis with granulomatous inflammation consistent with Crohn's disease (CD). | 23274739 |
| ARCN1 gene, Chronic Obstructive Airway Disease, Airway structure | Altered Intercellular Communication | Chronic obstructive pulmonary disease (COPD) is associated with chronic severe airway inflammation and causes increasing global health problems. | 23275209 |
| Degenerative polyarthritis, Inflammation | Altered Intercellular Communication | Inflammation might influence muscle strength in patients with knee OA. | 23275388 |
| Inflammation, Obesity | Altered Intercellular Communication | Moreover, the link between inflammation and obesity might explain the effect that BMI has in the associations between inflammatory markers (i.e. | 23275388 |
| Inflammation, Chronic diarrhea | Altered Intercellular Communication | Nonspecific changes (nonspecific chronic inflammation) in patients with chronic diarrhea represent the commonest diagnosis in colorectal biopsy interpretation, but these changes are of little clinical significance. | 23276179 |
| Inflammation, Eosinophilic inflammation | Altered Intercellular Communication | In AIG, inflammation was characterised by lymphocyte infiltration into the epithelium (98%), basal lymphoid aggregates (82.7%), basal predominance (59.6%), eosinophil infiltration [mean 34.5/high power field (HPF), >30 eosinophils/HPF in 46.1%] and neutrophil infiltration (44.2%). | 23277173 |
| Inflammation, Pancreatic aplasia, Eosinophilic inflammation | Altered Intercellular Communication | Compared to NGB, HPG, MAG and CG, AIG displayed more eosinophil infiltration (p < 0.001) and more frequent lymphocyte infiltration of the epithelium, basal predominant inflammation and pancreatic acinar metaplasia (all p > 0.05). | 23277173 |
| Inflammation, Compressed structure | Altered Intercellular Communication | If intravitreal antibiotics fail to control inflammation, early pars plana vitrectomy and silicone oil tamponade would be an appropriate option. | 23277209 |
| ARCN1 gene, Inflammation, Chronic Obstructive Airway Disease | Altered Intercellular Communication | The explanation for this chronic inflammation remains unclear, but may result from an impaired ability of alveolar macrophages to phagocytose apoptotic cells (a process termed 'efferocytosis'), as we have shown in chronic obstructive pulmonary disease (COPD). | 23278878 |
| ARCN1 gene, Inflammation, Asthma, Airway structure | Altered Intercellular Communication | Macrophage efferocytosis is impaired in non-eosinophilic asthma to a similar degree as that in COPD and may explain the persistent airway neutrophilia and chronic inflammation that characterizes this asthma subtype. | 23278878 |
| Inflammation, Diabetic Angiopathies | Altered Intercellular Communication | Complement-mediated chronic inflammation is associated with diabetic microvascular complication. | 23280928 |
| Inflammation, Diabetes Mellitus, Non-Insulin-Dependent | Altered Intercellular Communication | Chronic inflammation is characteristic of type 2 diabetes mellitus (T2DM). | 23280928 |
| Inflammation, Microangiopathy, Diabetic | Altered Intercellular Communication | We investigated the association between diabetic microangiopathy and complement-mediated inflammation in 32 obese T2DM patients and 32 normal donors. | 23280928 |
| Inflammation | Altered Intercellular Communication | Activation of the alternative complement pathway occurs in obese T2DM patients and is enhanced in the post-prandial hyperchylomicronic condition, which induces overproduction of ASP and C3a-mediated tissue inflammation. | 23280928 |
| Inflammation, Microangiopathy, Diabetic, macroangiopathy | Altered Intercellular Communication | Therefore, complement-mediated inflammation may contribute to the acceleration of diabetic microangiopathy in addition to the development of macroangiopathy. | 23280928 |
| Inflammation | Altered Intercellular Communication | RRMS patients showed higher CST Cho concentration than controls, and higher CST Ins concentration than PPMS, suggesting greater inflammation and glial proliferation in the RR than in the PP course. | 23281189 |
| Disability, Inflammation | Altered Intercellular Communication | In PPMS, lower CST Cho and Cr concentrations correlated with greater disability, suggesting that in the progressive stage of the disease, inflammation declines and energy metabolism reduces. | 23281189 |
| Inflammation, Atherosclerosis | Altered Intercellular Communication | Associations among lung function, arterial elasticity, and circulating endothelial and inflammation markers: the multiethnic study of atherosclerosis. | 23283358 |
| Inflammation, Endothelial dysfunction | Altered Intercellular Communication | Endothelial dysfunction and inflammation could potentially decrease elasticity of both vasculature and lung tissue. | 23283358 |
| Inflammation, Endothelial dysfunction | Altered Intercellular Communication | Spirometric data and markers of endothelial dysfunction and inflammation (soluble intracellular adhesion molecule-1, fibrinogen, hs-C-reactive protein, and interleukin-6) were obtained. | 23283358 |
| Inflammation | Altered Intercellular Communication | Inflammation was generally more frequent in the metatarsophalangeal (MTP) joints (221/292; 76 %) than in the proximal metatarsal (47/292; 16 %) and tarsal bones (24/292; 8 %). | 23283542 |
| Refractory anemias, Inflammation | Altered Intercellular Communication | Progress of inflammation in the MTP 1 was more frequently found in ERA patients than in patients with established RA (disease duration >12 months) (p = 0.002). | 23283542 |
| Inflammation | Altered Intercellular Communication | As a key encoding protein gene of MRN (MRE11-RAD50-NBS1) complex, NBS1 plays a crucial role in maintaining genomic stability and preventing cell apoptosis, inflammation and tumorgenesis. | 23283743 |
| Inflammation, Psoriasis, Inflammatory dermatosis, Hyperplasia, Histopathologic Grade differentiation | Altered Intercellular Communication | Psoriasis, a common inflammatory skin disease, is characterized by epidermal hyperplasia, abnormal differentiation, angiogenesis, immune activation, and inflammation. | 23283814 |
| Inflammation, Sleep Apnea Syndromes, Coronary Artery Disease, Dyslipidemias | Altered Intercellular Communication | Sleep apnoea, a frequent comorbidity of T2DM women, is associated with central fat, atherogenic dyslipidaemia, inflammation, worsening b-cell function, poorer glycaemic control and coronary artery disease risk. | 23283827 |
| Inflammation, Peritonitis | Altered Intercellular Communication | Peritoneal protein leakage, systemic inflammation, and peritonitis risk in patients on peritoneal dialysis. | 23284072 |
| Inflammation, Peritonitis | Altered Intercellular Communication | Baseline peritoneal protein leakage was able to independently predict risk for peritonitis, which is not explained by systemic inflammation. | 23284072 |
| Inflammation, Atherosclerosis | Altered Intercellular Communication | The role of inflammation in atherosclerosis is widely appreciated. | 23284878 |
| Inflammation, Atherosclerosis | Altered Intercellular Communication | High mobility group box 1 (HMGB1), an injury-associated molecular pattern molecule acting as a mediator of inflammation, has recently been implicated in the development of atherosclerosis. | 23284878 |
| Cessation of life, Inflammation, Malnutrition | Altered Intercellular Communication | Furthermore, low s-Mg and high s-Ca levels were independently associated with malnutrition, inflammation, arterial stiffening and risk of death. | 23285003 |
| Conjunctivitis | Altered Intercellular Communication | Clinically visible conjunctival inflammation was associated with increased S100A7, IL1B, CXCL5, MMP9 and MMP12 expression. | 23285311 |
| Inflammation, Pleural effusion disorder | Altered Intercellular Communication | Pentraxin-3 (PTX-3) is a relatively new marker of inflammation that has not been previously tested in pleural effusions. | 23286371 |
| Autoimmune hypoparathyroidism | Altered Intercellular Communication | Late primary autoimmune hypothyroidism in a patient with postdelivery autoimmune hypopituitarism associated with antibodies to growth hormone and prolactin-secreting cells. | 23286389 |
| Inflammation, Spasm | Altered Intercellular Communication | Although nonculprit artery perfusion may be improved after successful primary PCI, it is still lower than that in the control group, and may be involved in inflammation and spasms. | 23286472 |
| Granulomatous inflammation, Infection | Altered Intercellular Communication | Diagnosis is by clinical and histopathologic exclusion of other entities, which include other causes of granulomatous inflammation such as infections and foreign-body reactions. | 23286800 |
| Inflammation, Myopathy | Altered Intercellular Communication | Distal myopathy with rimmed vacuoles and inflammation: a genetically proven case. | 23287327 |
| Weakness, Inflammation | Altered Intercellular Communication | We report the first genetically proven case of DMRV from India in a 23-year-old male with gradual onset, progressive distal weakness of both lower limbs with features of inflammation in muscle biopsy. | 23287327 |
| Inflammation, Degenerative disorder | Altered Intercellular Communication | Bowman lecture on the role of inflammation in degenerative disease of the eye. | 23288138 |
| Inflammation | Altered Intercellular Communication | Inflammation, in the pathogenesis of many diseases previously thought to be strictly genetic, degenerative, metabolic, or endocrinologic in aetiology, has gradually entered the framework of a general mechanism of disease. | 23288138 |
| Inflammation | Altered Intercellular Communication | However, inflammation itself is not easy to define, and some aspects of inflammation may be beneficial, in a process described as 'para-inflammation' by Medhzitov. | 23288138 |
| Inflammation, Plaque, Atherosclerotic | Altered Intercellular Communication | High-mobility group box 1 (HMGB1), a DNA-binding cytokine expressed mainly by macrophages, contributes to lesion progression and chronic inflammation within atherosclerotic plaque. | 23288170 |
| Inflammatory Bowel Diseases | Altered Intercellular Communication | Here, we hypothesize that overexpression of miR-155 and miR-21, two inflammation-related microRNAs that target core MMR proteins, may constitute a pre-neoplastic event for the development of MSI IBD CRCs. | 23288924 |
| Inflammation, Congenital Abnormality | Altered Intercellular Communication | Patients undergoing hemodialysis (HD) have low plasma levels of zinc (Zn), high plasma levels of copper (Cu), and exhibit increased oxidative stress, inflammation, and immune abnormalities. | 23289009 |
| Granulomatous inflammation, Sarcoidosis | Altered Intercellular Communication | As a result of clinical, radiological and laboratory studies of the patients with granulomatous inflammation, 13 (38.2%) patients had TB, 21 (61.7%) patients had sarcoidosis. | 23289466 |
| Inflammation, Fibrosis Assessment, Pneumonia, Interstitial | Altered Intercellular Communication | The computerised tomography guided lung biopsy was reported as nonspecific interstitial pneumonia, liver biopsy was reported as portal inflammation and fibrosis. | 23289468 |
| Sample Size Calculation, Arthritis, Inflammation | Altered Intercellular Communication | The distribution, the MRI pattern and the predilection for the lunate bone raise the hypothesis that arthritis in SSc may be caused not only by immunological inflammation but also by ischemic mechanisms. | 23289906 |
| Airway structure, Exacerbation of asthma | Altered Intercellular Communication | The combination of theophylline plus SFC may provide greater protection against asthma exacerbations, and its administration is accompanied by significant improvements in small airway function and airway inflammation. | 23290154 |
| Inflammatory abnormality of the eye | Altered Intercellular Communication | The severity of ocular inflammation identified ranged from mild to severe AAU and thus required several weeks of treatment. | 23290982 |
| Inflammation, Coronary Arteriosclerosis, physiopathological, Diabetes Mellitus | Altered Intercellular Communication | This study demonstrates a close association between elevated levels of highly pro-inflammatory eicosonoids, diabetes and EPC dysfunction in patients with cardiac ischemia, indicating that chronic inflammation impact negatively on EPC function and angiogenic capacity in diabetes. | 23291334 |
| Inflammation, Anemia | Altered Intercellular Communication | Effect of ultrapure dialysate on markers of inflammation, oxidative stress, nutrition and anemia parameters: a meta-analysis. | 23291370 |
| Inflammation, Malnutrition | Altered Intercellular Communication | Markers of inflammation are linked to malnutrition and confer an increased mortality risk in hemodialysis patients. | 23291370 |
| Inflammation | Altered Intercellular Communication | Other markers of inflammation and oxidative stress displayed similar significant improvements. | 23291370 |
| Inflammation | Altered Intercellular Communication | 18F-fluorodeoxy glucose-positron emission tomography imaging showed significantly increased uptake by the LV and right ventricular walls, indicating active inflammation. | 23291676 |
| Acute inflammation, Cardiac sarcoidosis | Altered Intercellular Communication | The final diagnosis was thus cardiac sarcoidosis with acute inflammation. | 23291676 |
| Inflammation, Acute heart failure, Myocarditis, CTCAE 5.0 | Altered Intercellular Communication | This is a rare case in which acute inflammation led to acute heart failure mimicking acute myocarditis. | 23291676 |
| Arterial Stiffness, Inflammation | Altered Intercellular Communication | The AIx showed a significant positive correlation (r=0.28; p<0.001) with the serum high-sensitivity C-reactive protein concentration, as a marker of inflammation; with the urinary 8-iso-prostaglandin F2a concentration (r=0.31; p<0.001), as a marker of oxidative stress; and with the cardio-ankle vascular index (r=0.17; p<0.01), as a marker of systemic arterial stiffness. | 23291840 |
| Inflammation | Altered Intercellular Communication | These findings indicate that the AIx reflects inflammation, oxidative stress, and the urinary albumin concentration in patients with preserved kidney function. | 23291840 |
| Inflammation, Helicobacter pylori, Carcinogenesis | Altered Intercellular Communication | Chronic inflammation triggered by Helicobacter pylori causes altered DNA methylation in stomach mucosae, which is deeply involved in gastric carcinogenesis. | 23292007 |
| Gastritis | Altered Intercellular Communication | Methylation levels of the six CpG islands were consistently increased, and those of the two repetitive elements were consistently decreased in a stepwise manner with the activity of gastric inflammation as represented by serum marker levels. | 23292007 |
| Inflammation, Asthma | Altered Intercellular Communication | These novel findings suggest that rs12932187 and rs11074938 may constitute susceptibility markers of inflammation of the nasal passages in asthma patients. | 23292525 |
| Carcinoma of lung | Altered Intercellular Communication | Genetic single-nucleotide polymorphisms of inflammation-related factors associated with risk of lung cancer. | 23292870 |
| Orbital Pseudotumor | Altered Intercellular Communication | To identify and characterize patients with orbital masses in a monocentric cohort of 1142 GPA patients followed up from 1990 until the end of 2010 with regard to disease stage, local orbital inflammation, course of disease and outcome and to assess the efficacy of immunosuppressive treatment. | 23293138 |
| Inflammation, Autoimmune Chronic Hepatitis, Hepatitis | Altered Intercellular Communication | Liver biopsy was also typical of autoimmune hepatitis as attested by the presence of portal inflammation with predominant T-lymphocytes and plasma cells and interface hepatitis. | 23293207 |
| Inflammation, HIV Infections, SHD gene | Altered Intercellular Communication | SHD is frequent and correlates with inflammation in HIV infected patients. | 23295013 |
| Inflammation | Altered Intercellular Communication | The inflammation class (38% of ICCs) is characterized by activation of inflammatory signaling pathways, overexpression of cytokines, and STAT3 activation. | 23295441 |
| Inflammation | Altered Intercellular Communication | The inflammation class (38% of ICCs) is characterized by activation of inflammatory signaling pathways, overexpression of cytokines, and STAT3 activation. | 23295441 |
| Inflammation, Neoplasms | Altered Intercellular Communication | Inflammation is an important biological process involved in the development of many solid tumors. | 23295727 |
| Calculus of prostate, Benign prostatic hypertrophy, prostatitis | Altered Intercellular Communication | Lower urinary tract symptoms in benign prostatic hyperplasia patients: orchestrated by chronic prostatic inflammation and prostatic calculi?. | 23295780 |
| Calculus of prostate, Benign prostatic hypertrophy, prostatitis | Altered Intercellular Communication | This study aims to examine the relationship between chronic prostatic inflammation and prostatic calculi, and clinical parameters of benign prostatic hyperplasia (BPH). | 23295780 |
| Inflammation | Altered Intercellular Communication | Chronic inflammation was graded as 0 (n = 44), I (n = 54), II (n = 88) or III (n = 39) according to severity. | 23295780 |
| Inflammation, Calculi | Altered Intercellular Communication | The relationship between inflammation and calculus type was analyzed, and clinical parameters of BPH were compared for each group. | 23295780 |
| Inflammation, Calculi | Altered Intercellular Communication | There was no correlation between severity of inflammation and calculus type. | 23295780 |
| Inflammation | Altered Intercellular Communication | Prostatic volume increased with the severity of inflammation and showed significant differences between G2, G3 and G0. | 23295780 |
| Inflammation | Altered Intercellular Communication | The International Prostate Symptom Score also increased with increasing inflammation. | 23295780 |
| Calculus of prostate, Inflammation | Altered Intercellular Communication | Prostatic calculi had no significant association with chronic inflammation and clinical parameters of BPH. | 23295780 |
| Inflammation | Altered Intercellular Communication | Chronic inflammation was associated with the volume of the prostate and storage symptoms; thus, it is not only presumed to be related to the progression of BPH, but may also be one of the causes of lower urinary tract symptoms. | 23295780 |
| Inflammation, Diabetes Mellitus | Altered Intercellular Communication | In recent years, evidence has emerged indicating that insulin resistance and diabetes mellitus type 2 are associated with inflammation of adipose tissue (AT). | 23296264 |
| Malignant neoplasm of urinary bladder, Inflammation, Obesity, Abdominal, Diabetes Mellitus | Altered Intercellular Communication | We also observed a synergistic interaction between diabetes and high WHR in bladder cancer development that might be explained by increased insulin resistance and inflammation related to abdominal obesity. | 23296458 |
| Respiratory Failure, Pneumonitis | Altered Intercellular Communication | FiO2 0.40 in mechanically ventilated patients without severe respiratory failure did not increase systemic or pulmonary inflammation. | 23296630 |
| Inflammation | Altered Intercellular Communication | Histological investigation of the appendix revealed transmural acute inflammation, with diffuse proliferation of inflammatory cells, with characteristic intranuclear inclusion surrounded by a clear halo. | 23297526 |
| Inflammation, Uveitis | Altered Intercellular Communication | The dexamethasone (Ozurdex) implant seems comparable to the fluocinolone acetonide (Retisert) implant in preventing recurrence of noninfectious uveitis and in improving inflammation and BCVA. | 23297752 |
| Degenerative polyarthritis, Inflammation, Chondromalacia Patellae, Pain Distress Question | Altered Intercellular Communication | Osteoarthritis is characterized by progressive articular cartilage degeneration, changes in subchondral bone and synovial inflammation, leading to pain and disability. | 23298499 |
| Liver and Intrahepatic Biliary Tract Carcinoma, Inflammation | Altered Intercellular Communication | The mechanisms of progression in biliary tract cancer (BTC) with inflammation, including epithelial-mesenchymal transition (EMT), are not well understood. | 23298711 |
| Malignant Neoplasms, Neoplasms | Altered Intercellular Communication | We focused on two inflammation-associated cytokines, interleukin-6 (IL-6) and transforming growth factor-beta 1 (TGF-b1), and investigated their expression and activity, as well as their relationship to key features of malignancy, in tumour samples from patients with BTC and in cultured BTC cells. | 23298711 |
| Juvenile arthritis, Inflammation, Temporomandibular Joint, Soft tissue rheumatism, Juvenile rheumatoid arthritis | Altered Intercellular Communication | To differentiate between temporomandibular joint (TMJ) inflammation and myofascial pain (MPD) in children with juvenile idiopathic arthritis (JIA). | 23298802 |
| Arthritis, Myalgia, Asymmetry | Altered Intercellular Communication | Patients with clinical evidence (joint pain/tenderness, asymmetry, limited motion) and radiographic evidence (condylar asymmetry, flattening, accentuated antegonial notch) of TMJ inflammation but without muscle pain were diagnosed with arthritis. | 23298802 |
| Arthritis | Altered Intercellular Communication | Patients with TMJ inflammation and muscle pain/tenderness were considered to have co-existing arthritis and MPD. | 23298802 |
| Inflammation, Demographics Domain | Altered Intercellular Communication | In patients with type 2 DM, 12 weeks oral supplementation of vitamin D did not significantly affect vascular function or serum biomarkers of inflammation and oxidative stress. | 23298824 |
| Inflammation | Altered Intercellular Communication | Serum prealbumin is associated with short-term energy intake independently of the presence of multiple-organ involvement and inflammation. | 23298969 |
| Inflammation, Renal function | Altered Intercellular Communication | Its serum levels should be always interpreted in light of its influencing factors, among which inflammation and liver and kidney functions appear predominant. | 23298969 |
| Inflammation, Colorectal Carcinoma | Altered Intercellular Communication | The association between nutritional status and inflammation was assessed in patients with colorectal cancer and to verify their association with complications during anticancer treatment. | 23298973 |
| Inflammation | Altered Intercellular Communication | The nutritional status was defined by the SGA and the severity of inflammation was defined by the Glasgow Prognostic Score (GPS). | 23298973 |
| Inflammation, Adult Non-Hodgkin Lymphoma | Altered Intercellular Communication | Non-hodgkin lymphoma and circulating markers of inflammation and adiposity in a nested case-control study: the multiethnic cohort. | 23300021 |
| Inflammation, RTEL1 gene, Obesity, Adult Non-Hodgkin Lymphoma, Immune System Diseases | Altered Intercellular Communication | Because immune dysfunction is thought to underlie the development of non-Hodgkin lymphoma (NHL), obesity and chronic inflammation may be involved in its etiology. | 23300021 |
| Inflammation, RTEL1 gene | Altered Intercellular Communication | Although markers of inflammation and adiposity may provide new insights into the etiology of NHL, they need to be assessed many years before clinical diagnosis. | 23300021 |
| Inflammation, Adverse reaction to drug | Altered Intercellular Communication | A punch biopsy of skin from the patient's right lower abdomen revealed perivascular chronic inflammation with numerous eosinophils consistent with drug reaction. | 23300150 |
| Lactobacillus, Inflammation, Colitis | Altered Intercellular Communication | Finally, this Lactobacillus strain reduced inflammation in a murine model of colitis. | 23300685 |
| Inflammation, Injury of kidney, Chronic Kidney Diseases | Altered Intercellular Communication | Inflammation is a pathogenic factor in renal injury, but whether inflammation is related to renal outcome in chronic kidney disease (CKD) patients is little known. | 23300770 |
| Inflammation, Chronic Kidney Diseases | Altered Intercellular Communication | We thus assess the association of inflammation and renal outcome in an advanced CKD cohort. | 23300770 |
| Inflammation | Altered Intercellular Communication | Activated microglia is characterized by increased expression of the 18 kDa translocator protein (TSPO) in the brain and may be a useful biomarker of inflammation. | 23300829 |
| Inflammation, Elastosis perforans serpiginosa | Altered Intercellular Communication | Patients in this group exhibited a lower index of systemic inflammation and a longer symptomatic period than in EPS patients with biopsies of the "mixed" type (p<0.05). | 23300922 |
| Cytomegalovirus Infections, Inflammation | Altered Intercellular Communication | Collaborative studies suggested that both activating and inhibitory KIR and functionally relevant MBL2 haplotypes are important factors for control of CMV infection in the elderly and therefore for chronic low-grade inflammation. | 23302099 |
| Inflammation | Altered Intercellular Communication | Currently thoughts that environment factors and genes, oxidative damage, inflammation, immune reaction, imbalance between angiogenesis factors and anti-angiogenesis factors, etc. | 23302236 |
| Intraocular Infection, Intraocular inflammation | Altered Intercellular Communication | The intraocular infection of all 20 eyes was controlled, and the intraocular inflammation was relieved. | 23302273 |
| Granulomatous inflammation, Thrombosis, Vasculitis, CTCAE, Necrosis | Altered Intercellular Communication | Deep-seated necrosis, granulomatous inflammation against fungal organisms (3/19) and vasculitis with thrombosis (4/19) were not common. | 23302306 |
| Granulomatous inflammation | Altered Intercellular Communication | Granulomatous inflammation against fungal organisms were identified (16/16). | 23302306 |
| Inflammation, Depressed mood | Altered Intercellular Communication | In according with the down-regulated level of M-CSF, the polarization from M1 macrophages into M2 is depressed, and the inflammation induced by M1 is sustained. | 23302467 |
| Inflammation, Depression, CTCAE | Altered Intercellular Communication | Depression has been associated with inflammation, and inflammation may both influence and interact with growth factors such as brain-derived neurotrophic factor (BDNF). | 23303061 |
| Inflammation, Pancreatitis, Duodenal Ulcer | Altered Intercellular Communication | The spread of inflammation associated with the duodenal ulcer may have been one of the causes of groove pancreatitis. | 23303234 |
| Inflammation, Asthma, Eosinophilic granulomatosis with polyangiitis, Vasculitis, CTCAE | Altered Intercellular Communication | The Churg-Strauss syndrome (CSS), first described in 1951 and characterised by eosinophilic inflammation and necrotising vasculitis in patients with asthma can in principle affect any organ. | 23303591 |
| Inflammation, Rupture, Atherosclerotic lesion, GDC AJCC Clinical Stage Terminology | Altered Intercellular Communication | sEH inhibition regulated FAS and inhibited inflammation in cultured PBMCs from ACS patients, a mechanism that might prevent rupture of atherosclerotic lesions and protect against development of ACS. | 23305094 |
| Sepsis, Liver Abscess, Inflammation | Altered Intercellular Communication | Hepatic abscess should be suspected in neonates with UVC with sepsis and persistent signs of inflammation in spite of adequate antibiotic treatment. | 23305752 |
| Inflammation, Congenital anomaly of coronary artery | Altered Intercellular Communication | Compared with patients with typical KD, patients with NFKD were older, had more severe inflammation, and had similar rates of coronary artery abnormalities and resistance to intravenous immune globulin. | 23305955 |
| vascular inflammations | Altered Intercellular Communication | Markers of vascular inflammation were measured - before surgery and three months afterwards. | 23306174 |
| Inflammation, Benign prostatic hypertrophy, Necrosis | Altered Intercellular Communication | The prognostic use of inflammation and tissue necrosis in benign prostatic hyperplasia. | 23306308 |
| Inflammation, Benign prostatic hypertrophy | Altered Intercellular Communication | Evidence for the role of inflammation in benign prostatic hyperplasia (BPH) is conflicting. | 23306308 |
| Inflammation, Necrosis | Altered Intercellular Communication | Establishing the prognostic significance of local and systemic inflammation and tissue necrosis scoring systems in BPH may elucidate the potential of inflammatory pathways as a target of therapeutic intervention in these patients. | 23306308 |
| Inflammation, Necrosis, Failure (biologic function) | Altered Intercellular Communication | In 392 BPH patients, there was a trend for increased local inflammation and tissue necrosis to be associated with shorter time to failure of pre-operative medical treatment of BPH (p = 0.096 and 0.088, respectively). | 23306308 |
| Inflammation, Necrosis | Altered Intercellular Communication | The prognostic use of established scoring systems of systemic and local inflammation and tissue necrosis in BPH requires further investigation. | 23306308 |
| Inflammation | Altered Intercellular Communication | Periradicular injections of meloxicam (10 mg) appear to be a useful alternative to opioid and non-opiod analgesics for patients with intractable LBP due to nerve root inflammation. | 23306395 |
| Inflammation, Pain Distress Question | Altered Intercellular Communication | Adding steroid to local anaesthetics in local infiltration analgesia reduced inflammation both locally and systemically, resulting in significant early pain relief and rapid recovery in total knee arthroplasty. | 23306715 |
| Inflammation, Ulcerative Colitis | Altered Intercellular Communication | Therefore, it appears that the inflammation tends to subside with age in elderly patients with long-standing UC. | 23306844 |
| Inflammation, Cardiovascular Diseases, Left Ventricular Hypertrophy, Ventricular hypertrophy | Altered Intercellular Communication | Micro inflammation and cardiovascular disease such as left ventricular hypertrophy (LVH) are common in hemodialysis (HD) patients. | 23306861 |
| Acute cholangitis, Inflammation, Cholestasis | Altered Intercellular Communication | The diagnostic criteria of acute cholangitis have been revised as criteria to establish the diagnosis where cholestasis and inflammation demonstrated by clinical signs or blood test in addition to biliary manifestations demonstrated by imaging are present. | 23307001 |
| Inflammation, Dryness (characteristic) | Altered Intercellular Communication | Sensitivity and specificity of a point-of-care matrix metalloproteinase 9 immunoassay for diagnosing inflammation related to dry eye. | 23307206 |
| Inflammation, Dryness (characteristic) | Altered Intercellular Communication | Preoperative and perioperative management of inflammation related to dry eyes may reduce dry eyes that develop after laser in situ keratomileusis, improve wound healing, and reduce flap complications. | 23307206 |
| Cataract, Inflammation | Altered Intercellular Communication | Recognition of inflammation may allow for targeted perioperative therapeutic management of care for patients who undergo cataract and refractive surgery and improve outcomes. | 23307206 |
| Inflammation, Colorectal Carcinoma | Altered Intercellular Communication | The prognostic, especially predictive, values of inflammation indexes in advanced colorectal cancer were not established. | 23307251 |
| Malignant neoplasm of gastrointestinal tract | Altered Intercellular Communication | Arachidonic acid metabolic pathway has been implicated in the inflammation-associated tumorigenesis of gastrointestinal cancers. | 23307260 |
| Inflammation, Sacroiliac joint structure, Peripheral, Spondylitis | Altered Intercellular Communication | Ankylosing spondylitis (AS) is a chronic inflammation of the sacroiliac joints, spine and peripheral joints. | 23308121 |
| Inflammation, Metabolic Syndrome X | Altered Intercellular Communication | Inflammation and the metabolic syndrome: clustering and impact on survival in a Swedish community-based cohort of 75 year olds. | 23308380 |
| Unknown (origin) (qualifier value), Pneumonitis | Altered Intercellular Communication | The variation in accumulated DC-SIGN-positive cells might help to explain the differences in the development and maintenance of lung inflammation between idiopathic UIP and CVD-UIP. | 23311128 |
| palladium | Altered Intercellular Communication | Our study showed that PA declines significantly in PD patients, which might correlate with malnutrition-inflammation-atherosclerosis syndrome. | 23311233 |
| Airway structure, Lung diseases | Altered Intercellular Communication | Induced sputum is a non-invasive sampling technique for the analysis of airway inflammation in various lung diseases and comprises valuable potential for the identification of biomarkers and therapeutic targets by molecular methods. | 23312618 |
| Non-necrotizing granulomatous inflammation | Altered Intercellular Communication | Concomitant cytomegalovirus and non-necrotizing granulomatous inflammation were also observed. | 23312917 |
| Disability Assessment for Dementia Questionnaire, Hematoxylin and eosin stain method, Alveolar damage, Bronchiolitis, Acute Lung Injury, Vasculitis | Altered Intercellular Communication | The biopsy H&E slides were reviewed in a blinded fashion, and scored for presence of microvascular inflammation, acute rejection, bronchiolar inflammation and acute lung injury, as well as diffuse alveolar damage (DAD). | 23313559 |
| Vasculitis | Altered Intercellular Communication | Microvascular inflammation was graded by the presence of capillary neutrophils on a scale of 0 to 4(+). | 23313559 |
| Inflammation, Fatigue | Altered Intercellular Communication | Fatigue, low grip strength and markers of systemic inflammation were associated with short walking distance (P < 0.05). | 23314651 |
| Inflammation, Weight decreased, Fatigue | Altered Intercellular Communication | Weight loss, fatigue and markers of systemic inflammation were most strongly and consistently associated with adverse QoL, reduced functional abilities, more symptoms and shorter survival. | 23314651 |
| Conjunctival hyperemia | Altered Intercellular Communication | A second review of the false-positive cases' pCLE sequences (benign inflammatory) helped refine the existing classification by identifying four descriptive criteria specific to benign inflammatory conditions (Paris Classification): Vascular congestion, dark granular patterns with scales, increased inter-glandular space, and thickened reticular structure. | 23314855 |
| Inflammation | Altered Intercellular Communication | Decreased cingulate expression of EPHB2 may represent a compensatory mechanism minimizing excitotoxic injury in the face of chronic inflammation. | 23314923 |
| Necrotizing granulomatous inflammation | Altered Intercellular Communication | Punch skin biopsy as well as sural nerve biopsy demonstrated chronic granulomatous inflammation without evidence of Mycobacterium. | 23315459 |
| Fibrosis Assessment, Chronic lung disease | Altered Intercellular Communication | Cystic Fibrosis (CF) is a chronic lung disease characterized by chronic neutrophilic airway inflammation and increased levels of neutrophil elastase (NE) in the airways. | 23316069 |
| Inflammation | Altered Intercellular Communication | Importantly, senescent cells can be proinflammatory and would perpetuate CF chronic inflammation. | 23316069 |
| Inflammation, Non-alcoholic Fatty Liver Disease | Altered Intercellular Communication | Inflammation may have a pathogenic role in the progression of nonalcoholic fatty liver disease (NAFLD); by contrast, the role of anti-inflammatory molecules has not been addressed. | 23316084 |
| Calcification of mitral valve, Inflammation, Aortic Valve Stenosis | Altered Intercellular Communication | Valve calcification and inflammation play key roles in the development of aortic stenosis (AS). | 23316316 |
| Idiopathic Inflammatory Myopathies, Granulomatous peritonitis | Altered Intercellular Communication | Granulomatous peritonitis may indicate a number of infectious, malignant, and idiopathic inflammatory conditions. | 23318079 |
| Lichen Planus, Inflammation, Leukoplakia | Altered Intercellular Communication | Remaining cases were leukoplakia (n = 28), lichen planus (n = 15) and local inflammation (n = 8). | 23318121 |
| Inflammation, Traumatic injury | Altered Intercellular Communication | As this defect will make it vulnerable to injury, inflammation, and destruction by acidic and weakly acidic refluxates, it may in part explain incidences of recurrence of BE following ablation. | 23318477 |
| Inflammation | Altered Intercellular Communication | Active surveillance: does serial prostate biopsy increase histological inflammation? | 23318528 |
| Inflammation, Primary malignant neoplasm | Altered Intercellular Communication | Unpaired t-test and kh(2)-square analysis assessed variance in degree of inflammation and location of inflammation relative to cancer grade progression defined as Gleason sum increase. | 23318528 |
| Inflammation | Altered Intercellular Communication | A small, statistically significant increase in maximum chronic inflammation (CI) scores with greater number of repeat biopsies was observed. | 23318528 |
| Inflammation, Prostate carcinoma | Altered Intercellular Communication | In this pilot study of 56 men on AS for localized prostate cancer, degree of chronic histological inflammation increased with greater number of prostate biopsies, but was not associated with subsequent risk of grade progression. | 23318528 |
| Muscle damage, Actual blood loss, Acute inflammation | Altered Intercellular Communication | The use of a tourniquet during total knee arthroplasty was effective for reducing blood loss and avoiding excessive postoperative inflammation and muscle damage. | 23318610 |
| Inflammation, Liver Dysfunction | Altered Intercellular Communication | A total of 49 patients with unexplained liver dysfunction and undetermined inflammation were examined. | 23318849 |
| Inflammation, Klatskin Tumor | Altered Intercellular Communication | Resection for hilar cholangiocarcinoma: analysis of prognostic factors and the impact of systemic inflammation on long-term outcome. | 23319395 |
| Airway structure, ARCN1 gene, Asthma | Altered Intercellular Communication | In the subphenotype analysis, the differential expression of cytokines was more significant between eosinophilic and noneosinophilic airway inflammation than between asthma and COPD, according to both the ELISA and antibody array. | 23321180 |
| ARCN1 gene, Asthma, Airway structure | Altered Intercellular Communication | Differential expression of inflammatory mediators is present between patients with COPD or asthma, and eosinophilic or noneosinophilic airway inflammation, and contributes to understanding the cytokine network of airway inflammation. | 23321180 |
| Inflammation, Cirrhotic | Altered Intercellular Communication | Lipopolysaccharide (LPS)-expressing bacteria cause severe inflammation in cirrhotic patients. | 23321315 |
| Inflammation, Obesity | Altered Intercellular Communication | More research is essential to elucidate resistin's ontological role in the association between obesity, representing a chronic low-grade subclinical inflammation, and PBC. | 23321342 |
| Inflammation, Sleep Apnea, Obstructive | Altered Intercellular Communication | Platelet activation and inflammation are the related mechanisms of pathogenesis in obstructive sleep apnea syndrome (OSAS). | 23322273 |
| Inflammation, Sleep Apnea, Obstructive | Altered Intercellular Communication | C-reactive protein (CRP) and red cell distribution width (RDW) in relation to the inflammation in OSAS might be increased. | 23322273 |
| Autoimmune Diseases, Portal inflammation, Primary Biliary Cholangitis | Altered Intercellular Communication | Primary biliary cirrhosis (PBC) is a slowly progressing autoimmune disease of the liver that is characterized by portal inflammation and immune-mediated destruction of the intrahepatic bile ducts. | 23323253 |
| Airway structure, Asthma, Depression, CTCAE | Altered Intercellular Communication | Airway inflammation and hypothalamic-pituitary-adrenal axis activity in asthmatic adults with depression. | 23323569 |
| Airway structure, Asthma, Depression, CTCAE | Altered Intercellular Communication | To investigate the features of airway inflammation and hypothalamic-pituitary-adrenal axis (HPAA) activity in patients with asthma accompanied by depression. | 23323569 |
| Inflammation, Disease, Atherosclerosis | Altered Intercellular Communication | Leukotriene-based inflammation has been demonstrated to play a crucial role in atherosclerosis, a major risk factor for several human diseases. | 23324273 |
| Inflammation, Hematoma, Malignant Neoplasms | Altered Intercellular Communication | The FDG-PET findings of chronic expanding hematomas, including FDG uptake in the peripheral rim of the mass as a result of inflammation, should be recognized as a potential interpretive pitfall that mimics a malignant tumor. | 23324446 |
| Inflammation, Hypertension, CTCAE | Altered Intercellular Communication | Based on the recent studies that highlight the involvement of inflammation in the development of hypertension, we hypothesize that changes in DNA methylation of leukocytes are involved in the pathogenesis of hypertension. | 23325143 |
| Fibrosis, Liver, Inflammation, Hepatitis B, Chronic | Altered Intercellular Communication | Can mean platelet volume determine the severity of liver fibrosis or inflammation in patients with chronic hepatitis B? | 23325286 |
| Fibrosis, Liver, Inflammation | Altered Intercellular Communication | We aimed to determine whether mean platelet volume (MPV) is one of the variables that determine the severity of liver fibrosis and inflammation. | 23325286 |
| Inflammation, Fibrosis Assessment | Altered Intercellular Communication | The independent variables determining the severity of liver fibrosis and inflammation were investigated. | 23325286 |
| Hepatitis | Altered Intercellular Communication | The independent variables determining the severity of liver inflammation were serum HBV DNA, g-glutamyl transferase, and globulin levels and the MPV [odds ratio and P values were, respectively, 0.1001 and 0.046 for HBV DNA (x10); 1.016 and 0.004 for g-glutamyl transferase; 2.247 and 0.039 for globulin; and 1.488 and 0.004 for the MPV]. | 23325286 |
| Hepatitis | Altered Intercellular Communication | The sensitivity, specificity, and positive predictive value and negative predictive value of the model predicting the severity of liver inflammation were 60.5, 83, 40.3, and 91.7%, respectively (area under the receiver-operating characteristic curve=0.775, P=0.0001). | 23325286 |
| Hepatitis | Altered Intercellular Communication | MPV may provide useful information to predict the degree of liver inflammation along with other markers. | 23325286 |
| glycation, Carcinogenesis, Injury of liver, Inflammation | Altered Intercellular Communication | Binding of advanced glycation end products (AGEs) to their receptor (RAGE) increases oxidative stress and inflammation and may be involved in liver injury and subsequent carcinogenesis. | 23325627 |
| helium, Liver Cirrhosis | Altered Intercellular Communication | Interestingly, many genes counteracting pro-inflammatory signaling and inflammatory cytokine expression were up-regulated in the cerebral cortex of patients with liver cirrhosis and HE. | 23325665 |
| Inflammation | Altered Intercellular Communication | The initial injury is characteristically acute inflammation of gastric mucosa. | 23326152 |
| Inflammation, Prehypertension | Altered Intercellular Communication | Whey protein lycosome formulation improves vascular functions and plasma lipids with reduction of markers of inflammation and oxidative stress in prehypertension. | 23326213 |
| Inflammation, Ischemic stroke, Cerebrovascular accident | Altered Intercellular Communication | The high levels of MMP-9 in acute ischemic stroke document the involvement of this enzyme in the regulation of inflammation in stroke. | 23326959 |
| Ischemia, Inflammation, Carcinoma of lung, Neoplasms | Altered Intercellular Communication | Because the increase in lucigenin concentration, which is due to tissue ischemia, is higher than the increase in luminol, which is directly related to the presence and severity of inflammation, ischemia may be more important than inflammation for tumor development in patients with lung cancer. | 23327412 |
| Inflammation, Rosacea, Abnormality of the vasculature | Altered Intercellular Communication | Rosacea has a number of pathophysiological components, chief of which are vascular abnormalities and inflammation. | 23328356 |
| Inflammation | Altered Intercellular Communication | Inflammation is consistently present, even in the early forms, strongly suggesting a dual inflammatory and vascular mechanism. | 23328356 |
| Inflammation, Diabetic Angiopathies | Altered Intercellular Communication | Biomarkers of inflammation and angiogenesis may detect the progression of diabetic vascular disease and may lead towards earlier interventions that would prevent systemic complications. | 23328414 |
| ARCN1 gene, Inflammation | Altered Intercellular Communication | PGE2 is a critical component of an amplifying and self-perpetuating circle inducing senescence and inflammation in COPD fibroblasts. | 23328527 |
| ARCN1 gene, Inflammation | Altered Intercellular Communication | Modulating the described PGE2 signaling pathway could provide a new basis to dampen senescence and senescence-associated inflammation in COPD. | 23328527 |
| Inflammation, Malignant Neoplasms | Altered Intercellular Communication | Inflammation is an important cause of tumorigenesis in various types of malignancy. | 23328608 |
| Carcinogenesis, Prostate carcinoma | Altered Intercellular Communication | Inflammation of the prostate may act on prostate carcinomas; particularly that involving M2 macrophage infiltration may play a significant role in prostate carcinogenesis. | 23328608 |
| Crohn Disease, Inflammation | Altered Intercellular Communication | Mucosal addressin cell-adhesion molecule (MAdCAM)-1, which is overexpressed on gut endothelium in active Crohn's disease (CD), promotes intestinal recruitment of integrin a(4)b(7)(*) T cells that sustain chronic inflammation. | 23328772 |
| Inflammation | Altered Intercellular Communication | Postoperative healing was rapid with no unexpected inflammation, and no palpable bony defects were appreciated in the reconstructed cases. | 23328785 |
| Inflammation | Altered Intercellular Communication | IL-17/Th17 mediated synovial inflammation is IL-22 independent. | 23328939 |
| Inflammation | Altered Intercellular Communication | Interleukin (IL)-17A and Th17 cells are critically involved in T cell-mediated synovial inflammation. | 23328939 |
| Inflammation | Altered Intercellular Communication | However, it remains unclear whether IL-22 and Th22 cells contribute to T cell-mediated synovial inflammation. | 23328939 |
| Inflammation, Arthritis | Altered Intercellular Communication | Therefore, we examined the potential of IL-22 and Th22 cells to induce synovial inflammation and whether IL-22 is required for T cell-mediated experimental arthritis. | 23328939 |
| Inflammation, Arthritis | Altered Intercellular Communication | The in vivo IL-22 contribution to synovial inflammation was investigated by inducing T cell-mediated arthritis in IL-22 deficient mice and wild-type mice. | 23328939 |
| Inflammation, Arthritis | Altered Intercellular Communication | In line with this, similar synovial inflammation and disease severity was found between IL-22 deficient and wild-type mice in T cell-mediated experimental arthritis. | 23328939 |
| Inflammation | Altered Intercellular Communication | These findings show that IL-17A/Th17 cell-mediated synovial inflammation is independent of IL-22 and Th22 cells. | 23328939 |
| Pain Distress Question, Inflammation | Altered Intercellular Communication | Graft nephrectomy should be indicated in case of graft-related pain or a chronic inflammation syndrome. | 23328966 |
| Inflammation | Altered Intercellular Communication | The stroma is often edematous or has a granulation tissue-like appearance with acute or chronic inflammation. | 23328975 |
| Refractory anemias, Rheumatoid Arthritis, Inflammation | Altered Intercellular Communication | Calprotectin is potentially a more sensitive biomarker of disease activity in rheumatoid arthritis (RA) than conventional acute-phase proteins such as the erythrocyte sedimentation rate (ESR) and C-reactive protein (CRP) because it directly reflects inflammation in the synovium and synovial fluid rather than systemic inflammatory activity. | 23329363 |
| Inflammation, Benign prostatic hypertrophy | Altered Intercellular Communication | Our aim is to investigate how the chronic intraprostatic inflammation affect the course of the BPH (benign prostatic hyperplasia). | 23329532 |
| Inflammation, Lower Urinary Tract Symptoms | Altered Intercellular Communication | Between the dates of 2007-2011, the files of the patients who had TUR-P (transurethral resection of the prostate) and underwent open surgery were retrospectively reviewed because of BPH, and the patients were divided into two groups who were operated due to AUR (acute urinary retention) or LUTS (lower urinary tract symptoms) and the clinical data and pathology results of the two groups were compared in terms of chronic intraprostatic inflammation. | 23329532 |
| Inflammation | Altered Intercellular Communication | While there was chronic inflammation in 59 of the 130 patients, there was not in 71. | 23329532 |
| Inflammation | Altered Intercellular Communication | The risk of acute urinary retention is more frequent in patients with chronic inflammation than in those who lack. | 23329532 |
| Inflammation, Dental Plaque | Altered Intercellular Communication | In the margin and centre of the plaque the ratio appears skewed towards effector cells associated with inflammation. | 23330679 |
| Inflammation, Watery | Altered Intercellular Communication | Preceding symptoms of a watery eye with mucous discharge and a history or signs of inflammation are typical. | 23330705 |
| Autoimmune Diseases, Inflammation | Altered Intercellular Communication | While the chronic inflammation related to autoimmune diseases is known to be associated with an increased cardiovascular risk, much less is known about cerebrovascular risks. | 23330740 |
| Coughing, Inflammation | Altered Intercellular Communication | Chronic cough related to eosinophilic inflammation has become an important cause of cough in recent years. | 23331776 |
| Inflammation | Altered Intercellular Communication | The clinical presentation of Amyand's hernia varies, depending on the extent of inflammation involved in the hernial sac and the presence or absence of a scrotal abscess. | 23331784 |
| Pain Distress Question, Temporal Arteritis, Ischemia | Altered Intercellular Communication | The reason for the gradual pain relief after SGB is unclear, but we believe it was effective for ischemia in temporal arteritis because it led to dilation of affected arteries or suppression of inflammation/edema of the vascular wall. | 23332006 |
| Inflammation, Carotid Artery Diseases | Altered Intercellular Communication | Markers of inflammation and CD8 T-cell activation, but not monocyte activation, are associated with subclinical carotid artery disease in HIV-infected individuals. | 23332012 |
| Inflammation | Altered Intercellular Communication | All subjects were adults on stable ART with evidence of heightened T-cell activation (CD8(+)CD38(+)HLA-DR(+) >= 19%) or increased inflammation (high-sensitivity C-reactive protein >= 2 mg/L). | 23332012 |
| Inflammation, Vascular Diseases | Altered Intercellular Communication | Participants in SATURN-HIV have a high level of inflammation and immune activation that is associated with subclinical vascular disease despite low serum LDL cholesterol. | 23332012 |
| Genus Pneumocystis, Airway structure | Altered Intercellular Communication | Pneumocystis colonization has been associated with airway inflammation and obstruction. | 23333101 |
| Diabetes, Autoimmune, Insulitis, Inflammation, Diabetes Mellitus | Altered Intercellular Communication | NIT-hAAT has immunomodulatory properties, which delay the onset of autoimmune diabetes, reduce diabetes incidence, inhibit insulitis and b-cell apoptosis, and dampen transplant site inflammation. | 23333354 |
| Vasculitis | Altered Intercellular Communication | FDG-PET imaging could be more effective than CT-scan or magnetic resonance imaging in detecting the earliest stages of vascular wall inflammation. | 23333520 |
| Restless Legs Syndrome | Altered Intercellular Communication | Restless Legs Syndrome (RLS) is associated with impaired central dopaminergic neurotransmission. | 23333538 |
| Inflammation, Autonomic nervous system disorders | Altered Intercellular Communication | Increased body fat, autonomic dysfunction and low-grade chronic inflammation are interrelated risk factors implicated in the etiology of several chronic conditions normally presented by older adults. | 23333772 |
| Inflammation, Obesity | Altered Intercellular Communication | We previously demonstrated that angiopoietin-like protein 2 (Angptl2), a pro-inflammatory factor secreted by adipose tissue, promotes adipose tissue inflammation and subsequent systemic insulin resistance in obesity. | 23333801 |
| vascular inflammations, Intimal proliferation, Vascular System Injuries | Altered Intercellular Communication | Conversely, vascular inflammation and neointimal hyperplasia after endovascular injury were significantly attenuated in wild-type mice transplanted with Angptl2(-/-) mouse-derived perivascular adipose tissue compared to wild-type mice transplanted with wild-type tissue. | 23333801 |
| Communicable Diseases, Inflammation | Altered Intercellular Communication | FDG-PET/CT is useful for confirming the presence of graft infection by detecting high uptake around grafts and excluding other causes of inflammation. | 23333838 |
| Colitis | Altered Intercellular Communication | Incidental detection of colonic inflammation on PET/CT using 18F-FDG-labeled autologous leukocytes. | 23334139 |
| Inflammation, pseudomembranous colitis | Altered Intercellular Communication | While the pancreas showed no abnormal tracer uptake, colonic inflammation was incidentally detected, and a diagnosis of pseudomembranous colitis was subsequently confirmed on colonoscopy and biopsy. | 23334139 |
| Inflammation, Glaucoma, CTCAE | Altered Intercellular Communication | It is also important to recognize that concurrent conditions requiring treatment with topical medications, such as glaucoma, may be complicated after treatment because of the inflammation and ocular surface irritation after RT. | 23334313 |
| Inflammation, Swelling, Edema | Altered Intercellular Communication | Histology commonly shows capillary proliferation, swelling of endothelial cells, perivascular edema, and chronic inflammation with sparse lymphocytic infiltrate. | 23334520 |
| Inflammation, Serous retinal detachment | Altered Intercellular Communication | We reviewed the literature and discuss the possibility that laser-induced inflammation could rouse an inflammatory cascade mediated by proinflammatory cytokines and PAI-1, leading to the exacerbation of retinal serous detachment in susceptible patients. | 23335311 |
| Inflammation, Intraocular inflammation, Tubulointerstitial nephritis and uveitis, Uveitis, Nephritis, Interstitial | Altered Intercellular Communication | Tubulointerstitial nephritis and uveitis (TINU) syndrome usually shows anterior segment intraocular inflammation, but severe posterior segment intraocular inflammation is rarely observed. | 23335312 |
| Inflammation, Macular subretinal hemorrhage | Altered Intercellular Communication | The girl showed development of CNV with subretinal macular hemorrhage along with the exacerbation of anterior chamber inflammation in her left eye. | 23335312 |
| Inflammation, Subretinal hemorrhage | Altered Intercellular Communication | The boy showed subretinal hemorrhage from CNV with severe anterior chamber inflammation in his left eye. | 23335312 |
| Inflammation, Fibrosis Assessment, Subretinal hemorrhage | Altered Intercellular Communication | With oral prednisolone, anterior chamber inflammation and subretinal hemorrhage disappeared, but shrunken subretinal fibrosis in the macula remained. | 23335312 |
| Inflammation, Observation Method - Coagulation, Hepatitis | Altered Intercellular Communication | Biomarkers of inflammation and coagulation are associated with mortality and hepatitis flares in persons coinfected with HIV and hepatitis viruses. | 23335804 |
| Cessation of life, Inflammation, Observation Method - Coagulation, Hepatitis | Altered Intercellular Communication | Among HIV-positive patients coinfected with HBV and/or HCV who are initiating ART, biomarkers of inflammation and coagulation are associated with an increased risk of death, whereas HBV coinfection and higher pre-ART interleukin 10 levels are associated with hepatitis flares. | 23335804 |
| Genus Fusobacterium, Adenoma, Colonic mucous membrane, Inflammation | Altered Intercellular Communication | These results support a link between the abundance of Fusobacterium in colonic mucosa and adenomas and suggest a possible role for mucosal inflammation in this process. | 23335968 |
| Sepsis, Inflammation, Multiple Organ Failure, Bacterial Infections | Altered Intercellular Communication | Levels of APRIL were further elevated in sepsis and significantly correlated with classical markers of inflammation, bacterial infection, or multiorgan failure. | 23337484 |
| nervous system disorder, Inflammation, Nerve Degeneration | Altered Intercellular Communication | Multiple sclerosis is a neurological disorder that presents with symptoms including inflammation, neurodegeneration, and demyelination of the central nervous system (CNS). | 23339019 |
| Inflammation, Depression, CTCAE, Liver Cirrhosis | Altered Intercellular Communication | Because AST is an important mediator of inflammatory process, further research is needed to delineate the role of inflammation in the cirrhosis comorbid with depression. | 23339829 |
| Inflammation, Fluid overload, Chronic Kidney Diseases | Altered Intercellular Communication | Accumulating evidence suggests an association between body volume overload and inflammation in chronic kidney diseases. | 23340794 |
| methyldopa, Inflammation | Altered Intercellular Communication | It is well established that oxidative stress, inflammation, and apoptosis play critical roles in pathogenesis of AMD. | 23341606 |
| methyldopa, Inflammation | Altered Intercellular Communication | Here we show that mice lacking c-Jun N-terminal kinase 1 (JNK1) exhibit decreased inflammation, reduced CNV, lower levels of choroidal VEGF, and impaired choroidal macrophage recruitment in a murine model of wet AMD (laser-induced CNV). | 23341606 |
| methyldopa, Inflammation | Altered Intercellular Communication | These results suggest that JNK1 plays a key role in linking oxidative stress, inflammation, macrophage recruitment apoptosis, and VEGF production in wet AMD and pharmacological JNK inhibition offers a unique and alternative avenue for prevention and treatment of AMD. | 23341606 |
| Malignant neoplasm of penis, human papillomavirus, Chronic inflammation, Phimosis | Altered Intercellular Communication | Penile cancer is associated with a number of established risk factors and associated diseases including phimosis with chronic inflammation, human papillomavirus (HPV) infection, poor hygiene and smoking. | 23341933 |
| Eosinophilic disorder, Granulomatous inflammation, Meningitis | Altered Intercellular Communication | Previously unreported AEs like drug rash with eosinophilia and systemic symptoms (DRESS), granulomatous inflammation of the central nervous system, and aseptic meningitis, were documented. | 23341990 |
| Inflammation, Osage language, Cardiovascular Diseases, Renal function, Sleep Apnea, Obstructive | Altered Intercellular Communication | Both obstructive sleep apnea (OSA) and a novel lipocalin, neutrophil gelatinase associated lipocalin (Ngal), have been reported to be closely linked with cardiovascular disease and loss of kidney function through chronic inflammation. | 23342100 |
| Inflammation, Mammary Neoplasms | Altered Intercellular Communication | These findings link telomere content in breast tumors to the expression of several telomere-associated proteins previously shown to be negative regulators of telomere length in cell lines and suggest a link between the expressions of the telomere-associated proteins and mediators of stress and inflammation. | 23342266 |
| Inflammation | Altered Intercellular Communication | The lingual cervical coverage did not precipitate the accumulation of anaerobic microorganisms, although it could potentially induce gingival inflammation. | 23342333 |
| Inflammation, Dermatitis | Altered Intercellular Communication | We hypothesized that heterozygous FLG mutation carriers who suffer from dermatitis will have strongly reduced or even absent filaggrin levels during episodes of inflammation, potentially increasing the penetration of contact allergens, and hence the risk of becoming sensitized. | 23343419 |
| Granulomatous inflammation | Altered Intercellular Communication | Chalazion is a subacute granulomatous inflammation of the eyelid caused by retention of tarsal gland secretions and it's the most common inflammatory lesion of the eyelid. | 23343591 |
| Inflammation, Anemia | Altered Intercellular Communication | Inflammation was present in 48.0% of children and 20.8% of women and anemia was diagnosed in 57.6% of children and 38.8% of women. | 23343673 |
| Inflammation, Intradermal Route of Drug Administration | Altered Intercellular Communication | Research is needed to clarify the relationships between iron status indicators, particularly in the presence of inflammation, to harmonize global data on prevalence of ID. | 23343673 |
| Fibrinoid necrotizing inflammation | Altered Intercellular Communication | MMP expression in rheumatoid inflammation: the rs11568818 polymorphism is associated with MMP-7 expression at an extra-articular site. | 23343931 |
| Fibrinoid necrotizing inflammation | Altered Intercellular Communication | Less is known of the involvement of MMPs at extra-articular sites of rheumatoid inflammation. | 23343931 |
| Refractory anemias, Destruction of tissue, Inflammation, Rheumatoid Factor | Altered Intercellular Communication | We assessed the relative contribution from MMP-1, MMP-3, MMP-7 and MMP-12 to joint and extra-articular tissue destruction and inflammation by comparing gene expression in joint synovia and subcutaneous rheumatoid nodules from RA patients. | 23343931 |
| Inflammation | Altered Intercellular Communication | The high MMP-7 expression in nodules was associated with the single-nucleotide polymorphism (SNP) rs11568818 (-181A>G, MMP-7 promoter) and more active inflammation within the nodule lesions. | 23343931 |
| Fibrinoid necrotizing inflammation | Altered Intercellular Communication | MMP-12 expression reflects the involvement of monocyte/macrophages in rheumatoid inflammation. | 23343931 |
| ARCN1 gene, Inflammation, Chronic Obstructive Airway Disease | Altered Intercellular Communication | The aim of the study was to compare the serum levels of GGT (which is considered a novel marker of oxidative stress) between patients with stable chronic obstructive pulmonary disease (COPD) and those with acute exacerbation of COPD, and the relationship of GGT with inflammation. | 23344614 |
| Inflammation, Edema | Altered Intercellular Communication | Consequently, a CT scan of her abdomen was performed which showed mucosal oedema and inflammation involving virtually the entire length of her large bowel (the 'accordion sign'). | 23345475 |
| pseudomembranous colitis | Altered Intercellular Communication | In this case, the radiological appearance of the accordion sign which is traditionally known to be pathognomonic of pseudomembranous colitis, reveals that it may also be indicative of severe colonic luminal inflammation. | 23345475 |
| Granulomatous inflammation, Caseous necrosis | Altered Intercellular Communication | In both patients, diagnosis of TB-PE was established by demonstration of granulomatous inflammation, caseous necrosis and positive stain for acid-fast bacilli in pleural biopsy specimens. | 23345502 |
| Granulomatous inflammation, Congenital bronchogenic cyst | Altered Intercellular Communication | Pathological examination of the excised lobe showed a bronchogenic cyst combined with a destructive cavitary lesion with granulomatous inflammation. | 23346002 |
| Inflammation, Biliary calculi | Altered Intercellular Communication | Single-incision laparoscopic cholecystectomy (SILC) has been performed in patients with gallbladder stones without inflammation. | 23347708 |
| Inflammation, Specimen Type - Fistula, Fasciitis, septic | Altered Intercellular Communication | In 26 patients the diagnosis was a septic condition: abscess (12 patients), fistula (4), inflammation (9) and necrotizing fasciitis (1). | 23347777 |
| Inflammation, Observation Method - Coagulation | Altered Intercellular Communication | The protein C (PC) system is an important regulator of both coagulation and inflammation. | 23348224 |
| Autoimmune Diseases, Inflammation | Altered Intercellular Communication | The NLRP1 gene product is implicated in inflammation, autoimmune disorders, and caspase mediated apoptosis. | 23349227 |
| vascular inflammations | Altered Intercellular Communication | While angiopoietin (Ang)-1 protects from vascular inflammation and leakage, Ang-2 disrupts endothelial barrier function. | 23349297 |
| Inflammation, Chronic Lymphocytic Leukemia | Altered Intercellular Communication | The monocytic population in chronic lymphocytic leukemia shows altered composition and deregulation of genes involved in phagocytosis and inflammation. | 23349302 |
| Inflammation, Chronic Lymphocytic Leukemia | Altered Intercellular Communication | In conclusion, altered composition and deregulation of genes involved in phagocytosis and inflammation were found in blood monocytes obtained from chronic lymphocytic leukemia patients, suggesting that leukemia-mediated "education" of immune elements may also include the establishment of a skewed phenotype in the monocyte/macrophage population. | 23349302 |
| Inflammation, Asthma | Altered Intercellular Communication | Airway and systemic inflammation in obese children with asthma. | 23349447 |
| Inflammation, Asthma | Altered Intercellular Communication | Obese asthma presents via altered airway and systemic inflammation in adults. | 23349447 |
| Inflammation, Asthma, Obesity | Altered Intercellular Communication | Obesity was not associated with significantly altered airway or systemic inflammation in asthmatic children. | 23349447 |
| Inflammation, Obesity | Altered Intercellular Communication | Low-grade inflammation in obesity is associated with accumulation of the macrophage-derived cytokine osteopontin (OPN) in adipose tissue and induction of local as well as systemic insulin resistance. | 23349498 |
| vascular inflammations | Altered Intercellular Communication | A clinical evaluation of statin pleiotropy: statins selectively and dose-dependently reduce vascular inflammation. | 23349755 |
| vascular inflammations | Altered Intercellular Communication | Statins are thought to reduce vascular inflammation through lipid independent mechanisms. | 23349755 |
| Malaria, Falciparum, Inflammation | Altered Intercellular Communication | Since UA is associated with endothelial inflammation in non-malaria diseases, we hypothesized that elevated UA levels contribute to the endothelial pathology of P. falciparum malaria. | 23349902 |
| Airway structure, Asthma | Altered Intercellular Communication | Fractional exhaled nitric oxide (FENO), a non-invasive marker of eosinophilic airway inflammation, is increasingly used for diagnostic and therapeutic decisions in adult and paediatric asthma. | 23349918 |
| Crohn Disease, Inflammation | Altered Intercellular Communication | Crohn's Disease (CD)-associated inflammation is supposed to be driven by T helper (Th)1/Th17 cell-derived cytokines, even though there is evidence that the mucosal profile of cytokine may vary with the evolution of the disease. | 23349929 |
| Granulomatous inflammation, Mycobacterium Infections, Caseous necrosis, Malignant Neoplasms | Altered Intercellular Communication | Biopsy of the axillar lymph node was performed because of suspected malignancy, and the results showed that the lymph node had granulomatous inflammation with caseous necrosis and Langhans giant cells, suggestive of mycobacterial infection. | 23350517 |
| Inflammation, Fibrosis Assessment | Altered Intercellular Communication | Evidence indicates that liver fibrosis contains uncontrolled inflammation as a part of its etiology. | 23350952 |
| Inflammation, Albuminuria, Congestive heart failure, Chronic heart failure, Vascular System Injuries | Altered Intercellular Communication | Albuminuria might be a marker of the various pathophysiologic changes, such as diffuse vascular injury and systemic inflammation, that arise in patients with chronic heart failure (CHF). | 23351461 |
| Inflammation, Electrocardiogram: myocardial infarction (finding) | Altered Intercellular Communication | Inflammation in young adulthood is associated with myocardial infarction later in life. | 23351818 |
| Inflammation | Altered Intercellular Communication | During Swedish national conscription tests from 1969 through 1978, the erythrocyte sedimentation rate, as a measure of inflammation, was measured in 433,577 young Swedish men. | 23351818 |
| Inflammation, Extraocular rectus muscle, Muscle of orbit, Thyroid associated opthalmopathies | Altered Intercellular Communication | In the treatment of Graves' ophthalmopathy, rectus muscle resections generally are avoided because of the concern of reaggravating inflammation and creating excessive extraocular muscle restriction. | 23352720 |
| Inflammation | Altered Intercellular Communication | Moreover, we report the novel finding that IRS1 variant G972R (rs1801278) may contribute to oxidative DNA damage and inflammation. | 23353623 |
| Degenerative polyarthritis, Pain Distress Question, Inflammation | Altered Intercellular Communication | This study shows the efficacy of an AGE inhibitor on decreasing pain and inflammation, and increasing daily activity and mobility in OA patients. | 23354008 |
| Inflammation, Lung Diseases, Interstitial, Vasculitis, CTCAE | Altered Intercellular Communication | Histological examination demonstrated the presence of an obliterative vasculitis with interstitial pulmonary perivascular inflammation. | 23354025 |
| Data types - Address | Altered Intercellular Communication | Because several evidences show that patients might display quite different concentrations of neurotransmitters in brain areas, assessing metabolites in different and well-characterized AD stages should be investigated further. | 23354600 |
| Autoimmune Diseases, Inflammation | Altered Intercellular Communication | Although the etiology of MS is still not known, inflammation and autoimmunity are considered to be the central components of this disease. | 23354834 |
| Nonalcoholic Steatohepatitis, Steatohepatitis, Inflammation | Altered Intercellular Communication | Presence and severity of hepatic steatosis, lobular inflammation, and hepatocyte ballooning were more common among nonalcoholic steatohepatitis patients (all p < 0.001). | 23355033 |
| Inflammation, Atrophic | Altered Intercellular Communication | Histopathological analyses of labial salivary gland biopsies showed deposition of gelsolin amyloid, atrophy and inflammation. | 23356404 |
| Inflammation | Altered Intercellular Communication | Despite experimental evidence, clinical demonstration of acute state of oxidative stress and inflammation during post-cardiac arrest syndrome is lacking. | 23356570 |
| Inflammation | Altered Intercellular Communication | Plasma level of thioredoxin (TRX), a redox-active protein induced under conditions of oxidative stress and inflammation, is increased in various critical care conditions. | 23356570 |
| Cardiac Arrest, Inflammation | Altered Intercellular Communication | Our data show for the first time that TRX levels were elevated early following cardiac arrest, suggestive of oxidative stress and inflammation occurring with this condition. | 23356570 |
| Inflammation, Pain Distress Question | Altered Intercellular Communication | Most frequent complication of abutments was periodontal pocket formation (52%), followed by the inflammation (29%), increase in mobility (27%) and pain (4%). | 23356632 |
| Inflammation, Tissue injury | Altered Intercellular Communication | in cases with scarring or inflammation induced by tissue injury. | 23356949 |
| Schizophrenia | Altered Intercellular Communication | Alterations in glutamate transporter expression may lead to abnormal glutamate neurotransmission contributing to the pathophysiology of schizophrenia. | 23356950 |
| Inflammation, Neoplasms | Altered Intercellular Communication | Nonmalignant conditions, mainly inflammation and some benign tumors, however, can cloud the clinical picture by taking up FDG and producing a false-positive result. | 23357820 |
| Airway structure | Altered Intercellular Communication | Estrogen has previously been shown to increase the bioactivation of several compounds in tobacco smoke, which may enhance smoke-induced airway inflammation in fertile women. | 23357876 |
| Acute inflammation | Altered Intercellular Communication | The preoperative diagnosis included a high rate of acute biliary tract inflammation (24 of 38, 63.2 %). | 23359177 |
| Inflammation, Carcinogenesis, Colorectal Carcinoma | Altered Intercellular Communication | Our study confirmed the hypothesis that inflammation has a major effect on carcinogenesis of CRC. | 23359190 |
| Inflammation, physiopathological | Altered Intercellular Communication | However, pretreatment with glycyrrhizin attenuated LPS-induced acute peritoneal inflammation and dysfunction in mice. | 23359306 |
| Dermatitis | Altered Intercellular Communication | Keratinocyte overexpression of IL-17C promotes psoriasiform skin inflammation. | 23359500 |
| Psoriasis, Dermatitis | Altered Intercellular Communication | These findings identify a role for IL-17C in skin inflammation and suggest a pathogenic function for the elevated IL-17C observed in lesional psoriasis skin. | 23359500 |
| Psoriasis | Altered Intercellular Communication | Psoriasis patients treated with etanercept rapidly decrease cutaneous IL-17C levels, suggesting IL-17C/TNF-a-mediated inflammatory signaling is critical for psoriasis pathogenesis. | 23359500 |
| Airway Obstruction, Inspiratory stridor | Altered Intercellular Communication | The different types of foreign body impaction in the throat and the inflammatory condition of throat or the inspiratory stridor due to upper airway obstruction were the main emergency situation recorded. | 23360039 |
| Inflammation, Pancreatic Ductal Adenocarcinoma | Altered Intercellular Communication | To test whether or not the association between inflammation and pancreatic ductal adenocarcinoma (PC) is facilitated by host susceptibility, specifically by genetic polymorphisms in inflammation-related genes. | 23360921 |
| Inflammation, Chronic Kidney Diseases | Altered Intercellular Communication | Effects of high-dose cholecalciferol on serum markers of inflammation and immunity in patients with early chronic kidney disease. | 23361158 |
| Inflammation, Chronic Kidney Diseases | Altered Intercellular Communication | We aimed to determine if high-dose cholecalciferol supplementation for 1 year in subjects with early chronic kidney disease (CKD) improved circulating markers of inflammation and immunity. | 23361158 |
| Inflammation, Squamous cell carcinoma | Altered Intercellular Communication | A single false-positive case was dense inflammation with squamous cells misinterpreted as squamous cell carcinoma (SCC) on cytology. | 23361285 |
| Inflammatory Bowel Diseases, Inflammation | Altered Intercellular Communication | Osteopontin: participation in inflammation or mucosal protection in inflammatory bowel diseases? | 23361573 |
| Inflammation, Colitis | Altered Intercellular Communication | OPN promoted the Th1 immune response and strengthened inflammation in the mouse colitis model. | 23361573 |
| Inflammation, Metabolic Diseases | Altered Intercellular Communication | Increased inflammation and oxidative stress are associated with insulin resistance (IR) and metabolic disorders. | 23361591 |
| Inflammation, Fibrosis Assessment, Crohn Disease | Altered Intercellular Communication | Detecting active inflammation and fibrosis in pediatric Crohn's disease: prospective evaluation of MR-E and CT-E. | 23361877 |
| Crohn Disease, Fibrosis Assessment, Inflammation | Altered Intercellular Communication | Symptoms of Crohn's disease (CD) can be due to active inflammation or fibrosis. | 23361877 |
| Inflammation, Fibrosis Assessment | Altered Intercellular Communication | The purpose of our study was to compare the ability of MR-E and CT-E to assess for active inflammation and mural fibrosis in patients with known CD as compared to a histologic reference standard. | 23361877 |
| Inflammation, Fibrosis Assessment | Altered Intercellular Communication | These were evaluated by the pathologist for active inflammation and fibrosis. | 23361877 |
| Inflammation, Fibrosis Assessment | Altered Intercellular Communication | We found that while CT-E and MR-E were similar in their accuracies of depicting active inflammation, MR-E was significantly more sensitive in detecting fibrosis. | 23361877 |
| Fibrous, Inflammation, Dental Plaque, Calcinosis | Altered Intercellular Communication | Compared with plaques from patients with ocular events only, those from patients with cerebral events had significantly more large lipid core (odds ratio [OR], 1.38; 95% confidence interval [CI], 1.05-1.82; P=0.02), inflammation (OR, 1.32; 95% CI, 1.02-1.72; P=0.04) and overall plaque instability (OR, 1.37; 95% CI, 1.05-1.80; P=0.02), and less fibrous content (OR, 0.71; 95% CI, 0.54-0.92; P=0.01), and calcification (OR, 0.70; 95% CI, 0.54-0.91; P=0.008). | 23362077 |
| Inflammation | Altered Intercellular Communication | PRC also orchestrates a robust response to metabolic stress by promoting the expression of multiple genes specifying inflammation, proliferation, and metabolic reprogramming. | 23364789 |
| Sepsis | Altered Intercellular Communication | Sepsis is an excessive inflammatory condition with a high mortality rate and limited prediction and therapeutic options. | 23365080 |
| Inflammation, White matter degeneration, Traumatic | Altered Intercellular Communication | Inflammation and white matter degeneration persist for years after a single traumatic brain injury. | 23365092 |
| Inflammation, White matter degeneration, Traumatic | Altered Intercellular Communication | These data present striking evidence of persistent inflammation and ongoing white matter degeneration for many years after just a single traumatic brain injury in humans. | 23365092 |
| Inflammation, White matter degeneration | Altered Intercellular Communication | Future studies to determine whether inflammation occurs in response to or, conversely, promotes white matter degeneration will be important. | 23365092 |
| Inflammation, Spondylitis, Rheumatism | Altered Intercellular Communication | Inflammation driven connective tissue turnover is key in rheumatic diseases, such as ankylosing spondylitis (AS). | 23365672 |
| Inflammation | Altered Intercellular Communication | Type II collagen is the primary structural protein of cartilage and type III collagen of connective tissues, and obvious targets for the collagenalytic, which increase during tissue inflammation. | 23365672 |
| Inflammation, Irritation | Altered Intercellular Communication | Although orthopedic implants are known to cause irritation and inflammation, to our knowledge, this is the first case report to describe a patient with rice bodies secondary to an orthopedic implant. | 23365810 |
| Respiratory Distress Syndrome, Adult, Inflammation, Respiratory Distress Syndrome, Newborn | Altered Intercellular Communication | Acute Respiratory Distress Syndrome (ARDS) is characterized by inflammation, filling of the lung with fluid and the collapse of lung units. | 23368982 |
| Inflammation, Structure of parenchyma of lung | Altered Intercellular Communication | WNT signalling is activated during lung tissue damage and inflammation. | 23370438 |
| Airway structure, ARCN1 gene | Altered Intercellular Communication | As WNT-4 further increases CSE-induced pro-inflammatory cytokine release in bronchial epithelium, we propose that higher epithelial WNT-4 levels in combination with cigarette smoking may have important implications for the development of airway inflammation in COPD. | 23370438 |
| Inflammation, Diabetes Mellitus, Non-Insulin-Dependent, Cardiovascular Diseases | Altered Intercellular Communication | Chronic sub-acute inflammation contributes to the pathogenesis of type 2 diabetes mellitus and cardiovascular disease. | 23370525 |
| Inflammation | Altered Intercellular Communication | It resolved in five patients with well-controlled inflammation, but was progressive in all of the other patients. | 23371008 |
| Inflammation, Tissue injury | Altered Intercellular Communication | This is possibly due to the activation of cytoprotective pathways resulting in limitation of the tissue injury secondary to inflammation. | 23371318 |
| Inflammation | Altered Intercellular Communication | Because CXCL2 could represent a WAT-produced chemokine, we explored its role in obesity-associated inflammation. | 23372021 |
| Inflammation, Obesity | Altered Intercellular Communication | Activated neutrophils in obesity may influence vis WAT-ECs functions and contribute to WAT inflammation. | 23372021 |
| Inflammation, "Huntingtons Disease Pathway | Altered Intercellular Communication | A critical role of astrocyte-mediated nuclear factor-kB-dependent inflammation in Huntington's disease. | 23372043 |
| HD Term Type, Inflammation | Altered Intercellular Communication | Thus, HD glia might play an important role in chronic inflammation that accelerates disease progression in HD mice. | 23372043 |
| HD Term Type, Neurogenic Inflammation | Altered Intercellular Communication | Therapeutic interventions aimed at preventing neuronal inflammation may be an important strategy for treating HD. | 23372043 |
| Inflammation, Bacterial Infections | Altered Intercellular Communication | Down-regulation of miR-150 was recently linked to inflammation and bacterial infection. | 23372743 |
| Crohn Disease | Altered Intercellular Communication | Suppression of Crohn's disease inflammation potentially leads to the control of amyloid A production, assessed by a decrease of serum amyloid A. Kidney transplantation provides a long survival. | 23373823 |
| Inflammation, Appendicitis, CTCAE | Altered Intercellular Communication | Stump appendicitis is a rare disease characterized by inflammation of the appendiceal remnant. | 23374389 |
| Inflammation, Liver carcinoma | Altered Intercellular Communication | The Glasgow Prognostic Score, an inflammation based prognostic score, predicts survival in patients with hepatocellular carcinoma. | 23374755 |
| Inflammation, Elastosis perforans serpiginosa | Altered Intercellular Communication | The degree of inflammation in the EPS specimens progressively increased with age, education, and body mass index (P <.001 for trend for all). | 23374811 |
| vascular inflammations | Altered Intercellular Communication | Statins are frequently administered to reduce low-density lipoprotein cholesterol (LDL-C) and vascular inflammation, because LDL-C and high sensitive C-reactive protein (hs-CRP) are associated with high risk for cardiovascular events. | 23374898 |
| Inflammation, Pseudomembrane | Altered Intercellular Communication | Colonoscopy showed diffuse inflammation in the entire large bowel and pseudomembranes in the sigmoid colon. | 23375026 |
| Inflammation, Diabetes Mellitus, Non-Insulin-Dependent, Chronic Kidney Diseases, Obesity | Altered Intercellular Communication | Chronic low-grade inflammation and/or obesity are suggested to induce chronic kidney disease (CKD) in patients with type 2 diabetes. | 23375231 |
| Inflammation, Tropical Spastic Paraparesis | Altered Intercellular Communication | HTLV-1-associated inflammatory myopathies: low proviral load and moderate inflammation in 13 patients from West Indies and West Africa. | 23375238 |
| Tissue damage, Inflammation | Altered Intercellular Communication | Muscle biopsies were used for a broad immunohistological evaluation of tissue damage and inflammation, as well as identification of infected cells through in situ hybridization. | 23375238 |
| Inflammation, Idiopathic eosinophilic myositis | Altered Intercellular Communication | Histological alterations and inflammation in patients muscles were mostly moderate, with classical features of idiopathic myositis and rare HTLV-1-infected infiltrating cells. | 23375238 |
| Myositis | Altered Intercellular Communication | We show here that muscle inflammation is moderate in HAIM, and accompanied by a low HTLV-1 proviral load, suggesting that the pathogenetic events do not exactly mirror those of other HTLV-1-associated inflammatory diseases. | 23375238 |
| Communicable Diseases, Inflammation | Altered Intercellular Communication | Lipocalin-2 (LCN-2), which is expressed in immunocytes as well as hepatocytes, is upregulated in cells under stress from infection or inflammation with increase in serum levels. | 23375308 |
| Inflammation, Hypoxia, Anemia, hepcidin | Altered Intercellular Communication | Hepcidin, produced by hepatocytes in response to anemia, hypoxia, or inflammation, is a key regulator of iron homeostasis. | 23375326 |
| Inflammation, Anemia, Chronic disease | Altered Intercellular Communication | This form of anemia in mTOR-treated OHT resembles the disorder of chronic disease, suggesting that OHT patients show low-grade inflammation, which should be investigated for underlying, potentially reversible causes. | 23375326 |
| Inflammation, Hypoxia, Anemia, hepcidin | Altered Intercellular Communication | Hepcidin is a small defensin-like peptide whose production by hepatocytes is modulated in response to anemia, hypoxia, or inflammation. | 23375327 |
| Inflammation, Corneal Endothelial Cell Loss | Altered Intercellular Communication | Impaired kidney function was strongly associated with endothelial damage and inflammation. | 23375328 |
| Granulomatous inflammation, Hyperplasia | Altered Intercellular Communication | Other histopathological features encountered included perieccrine infiltration (n = 5), focal subcutaneous involvement (n = 4), granulomatous inflammation (n = 3), epidermal hyperplasia (n = 2), and 1 each of infiltration of muscle bundles, numerous eosinophils in the infiltrate, and angiocentricity. | 23375516 |
| Inflammation, Cystitis, Granulomatous inflammation, Nephrogenic metaplasia, Squamous metaplasia | Altered Intercellular Communication | Of the 85 nonneoplastic cases, prominent morphologic findings included significant chronic inflammation (59), granulomatous inflammation including foreign body giant cell reaction (6), acute inflammation (7), squamous metaplasia (9), cystitis glandularis (10), and nephrogenic metaplasia (2). | 23375647 |
| Inflammation, Complications of Diabetes Mellitus | Altered Intercellular Communication | Advanced glycation end-products (AGEs) play a pivotal role in the development of diabetic complications by inducing inflammation. | 23376161 |
| Intraocular inflammation | Altered Intercellular Communication | Treatment outcome was ascertained by a composite endpoint comprised of visual acuity, intraocular inflammation, ability to taper immunosuppressives, and posterior segment imaging. | 23376607 |
| Intraocular inflammation | Altered Intercellular Communication | Clinical response was defined by improvement in at least one parameter, worsening in none, and well controlled intraocular inflammation. | 23376607 |
| Gastrointestinal inflammation | Altered Intercellular Communication | Fecal S100A12 has been reported as a novel marker of intestinal inflammation. | 23377171 |
| Tumor necrosis, Inflammation, Pain Distress Question | Altered Intercellular Communication | Despite treatment with a tumor necrosis factor blocking agent, the patient was not pain free and inflammation markers remained elevated. | 23377199 |
| Inflammation, Depression, CTCAE, Cerebrovascular accident | Altered Intercellular Communication | Sustained inflammation 1.5 years post-stroke is not associated with depression in elderly stroke survivors. | 23378749 |
| Inflammation, Depression, CTCAE, Cerebrovascular accident | Altered Intercellular Communication | Depression is common in elderly stroke survivors and has been associated with systemic inflammation. | 23378749 |
| Inflammation, Cerebrovascular accident | Altered Intercellular Communication | We aimed to investigate an elderly population of Swedish stroke patients for evidence of sustained peripheral inflammation 18 months post-stroke and to identify if inflammation is associated with post-stroke depression at 18 months post-stroke. | 23378749 |
| Hepatic inflammation | Altered Intercellular Communication | The degree of hepatic inflammation was graded using the histological activity index (HAI). | 23379437 |
| Inflammation, Complete atrioventricular block | Altered Intercellular Communication | Peripheral Th17 cell frequency is associated closely with inflammation activity of liver tissues in paediatric patients with CHB. | 23379437 |
| Communicable Diseases, Inflammation | Altered Intercellular Communication | Our study shows that catheters might contribute to increased inflammation independent of infection, and support the avoidance of catheters and a timely conversion to fistulas with catheter removal. | 23379491 |
| Inflammation, Antigen T Cell Receptor, beta Chain | Altered Intercellular Communication | Hemodialysis (HD) patients are characterized by impaired T-cell function at least in part because of T-cell zeta-chain downregulation due to inflammation. | 23379493 |
| Inflammation, Periodontitis, Tooth Loss | Altered Intercellular Communication | Tooth loss and periodontitis by socio-economic status and inflammation in a longitudinal population-based study. | 23379538 |
| Inflammation, Periodontitis, Tooth Loss | Altered Intercellular Communication | To examine the associations between factors of socio-economic status (SES), systemic inflammation and the progression of periodontitis and incidence of tooth loss. | 23379538 |
| Sepsis, Inflammation | Altered Intercellular Communication | During sepsis, inflammation can be orchestrated by the interaction between circulating and vascular cells that, under activation, release MPs (microparticles). | 23379624 |
| Post-Traumatic Stress Disorder, Inflammation | Altered Intercellular Communication | Association between posttraumatic stress disorder and inflammation: a twin study. | 23379997 |
| Post-Traumatic Stress Disorder, Inflammation, Cardiovascular Diseases | Altered Intercellular Communication | The association of posttraumatic stress disorder (PTSD) with cardiovascular disease risk may be mediated by inflammation. | 23379997 |
| Post-Traumatic Stress Disorder, Inflammation | Altered Intercellular Communication | Our objective was to examine the association between PTSD and measures of inflammation and to determine whether these associations are due to shared familial or genetic factors. | 23379997 |
| Cessation of life, Inflammation, Abnormality of mitochondrial metabolism | Altered Intercellular Communication | There have been major advances in the understanding of mechanisms that contribute to nigral dopaminergic cell death, including mitochondrial dysfunction, oxidative stress, altered protein handling, and inflammation. | 23380027 |
| Inflammation | Altered Intercellular Communication | We investigated how loss of PTPN22 could contribute to chronic inflammation of the intestine. | 23380085 |
| Airway structure | Altered Intercellular Communication | Maternal smoking affects lung function and airway inflammation in young children with multiple-trigger wheeze. | 23380219 |
| Degenerative polyarthritis, Inflammation | Altered Intercellular Communication | The presumed chronic inflammatory etiology of osteoarthritis suggests that nociceptive processes and neurogenic inflammation predominate in this condition. | 23380268 |
| Inflammation, "Alzheimers Disease", Data types - Address | Altered Intercellular Communication | Immune activation and inflammation play significant roles in the pathogenesis of Alzheimer's disease (AD). | 23380586 |
| Communicable Diseases, Inflammation, Ear Inflammation | Altered Intercellular Communication | Toll-like receptors are considered to be important factors for clearance of infection and resolution of inflammation in otitis media. | 23380629 |
| Communicable Diseases, Inflammation | Altered Intercellular Communication | Although there was no definite infection or inflammation, careful follow-up was considered to be mandatory. | 23381366 |
| Orchitis | Altered Intercellular Communication | 94% of patients with C-reactive protein values <10 mg/dl showed early stages of appendicular inflammation (p<0,05). | 23381749 |
| Hypertensive (finding) | Altered Intercellular Communication | N-terminal rather than full-length osteopontin or its C-terminal fragment is associated with carotid-plaque inflammation in hypertensive patients. | 23382482 |
| Inflammation, Hypertensive (finding), atherosclerotic | Altered Intercellular Communication | Hypertensive patients develop carotid atherosclerotic plaques with enhanced inflammation. | 23382482 |
| Inflammation, Hypertensive (finding) | Altered Intercellular Communication | We conducted a study to examine whether plaque inflammation in hypertensive patients corresponds to the expression of OPN or of its cleaved forms or both. | 23382482 |
| Inflammation | Altered Intercellular Communication | Moderate to heavy staining for OPN characterized 87% of the plaques with high-degree inflammation but only 44% of those with low-degree inflammation, corresponding to the percentages of plaques that were heavily stained for the macrophage marker CD68 (93% versus 26%, respectively, P < 0.01). | 23382482 |
| Inflammation | Altered Intercellular Communication | The abundance of MMP-12 was significantly greater in the high- than in the low-degree plaque inflammation group (4.8 (range 1.9-8.8) vs. 1.1 (range 0.3-1.4), respectively; P = 0.03). | 23382482 |
| Hypertensive (finding) | Altered Intercellular Communication | The N-terminal fragment of osteopontin, rather than OPN-FL or OPN-C, is associated with carotid plaque inflammation in hypertensive patients. | 23382482 |
| CLU protein, human | Altered Intercellular Communication | The results of this study suggest that inflammation-induced BM exhaustion and a disturbed progenitor cell mobilization response due to reduced levels and activity of MMP-9 in the BM and alterations in the SDF-1a/CXCR4 interaction contribute to the attenuated neovascularization in CLI patients. | 23383236 |
| Inflammation, Structure of parenchyma of lung | Altered Intercellular Communication | In this progressive disease, chronic inflammation in the lung contributes to lung tissue destruction leading to the formation of chemotactic collagen fragments such as N-acetylated Proline-Glycine-Proline (N-ac-PGP). | 23383243 |
| Inflammation, Pulmonary Emphysema, Neutrophil Infiltration | Altered Intercellular Communication | This study indicates that neutrophils activated by cigarette smoke extract can breakdown collagen into N-ac-PGP and that this collagen fragment itself can activate neutrophils, which may lead in vivo to a self-propagating cycle of neutrophil infiltration, chronic inflammation and lung emphysema. | 23383243 |
| Pain Distress Question, Inflammation, Communicable Diseases, Swelling, Fracture, Infection of bone | Altered Intercellular Communication | Based on their experience and a review of the literature, the authors suggest that bone infection be considered for patients with closed fractures complicated by excessive or prolonged pain and swelling with evident signs of inflammation where no other obvious infection is apparent. | 23383681 |
| Barrett Esophagus, Inflammation | Altered Intercellular Communication | Barrett's esophagus (BE) is considered a complication of the inflammation provoked by acid and bile reflux. | 23384184 |
| Angiomyolipoma, Inflammation, Renal Cell Carcinoma Pathway | Altered Intercellular Communication | Pathology revealed angiomyolipoma (3), renal cell carcinoma (2), and chronic inflammation (1). | 23384321 |
| Gastrointestinal inflammation | Altered Intercellular Communication | Endoscopy should be decided based on clinical criteria, but also driven by noninvasive tests to assess the digestive absorptive functions and intestinal inflammation. | 23384809 |
| Inflammation | Altered Intercellular Communication | Robust shifts in S100a9 expression with aging: a novel mechanism for chronic inflammation. | 23386971 |
| Inflammation | Altered Intercellular Communication | These findings offer support for a novel mechanism by which a SPI1/PU.1-S100a9 axis sustains chronic inflammation during aging. | 23386971 |
| Inflammation, Infection | Altered Intercellular Communication | They are based on spreading infections from focal sources of inflammation in abdomen or damaged intestinal wall. | 23387814 |
| Inflammation, Benign prostatic hypertrophy | Altered Intercellular Communication | In 88,22+-1,67% of cases nodular prostatic hyperplasia was combined with diffuse or focal inflammation, engorgements of prostate gland secretion were observed in 81,76+-2,97%. | 23388536 |
| Inflammation | Altered Intercellular Communication | Inflammation is associated with future SBP in the Taiwanese population. | 23388833 |
| Hypertensive disease, Inflammation, Dyslipidemias | Altered Intercellular Communication | In summary, these data suggest a complex relationship between inflammation and HTN with dyslipidemia. | 23388885 |
| Inflammation | Altered Intercellular Communication | Diagnostic microdialysis can detect local inflammation and may predict the development of CLS early before severe clinical signs appear. | 23389476 |
| Hepatic inflammation | Altered Intercellular Communication | Here, we considered both liver fat burden measured by CT (FL) and the non-specific measure of hepatic inflammation -alanine aminotransferase (ALT). | 23390892 |
| palladium | Altered Intercellular Communication | Malnutrition-inflammation score predicts long-term mortality in Chinese PD patients. | 23391316 |
| palladium, Malnutrition | Altered Intercellular Communication | MIS is a promising marker for malnutrition inflammation assessment and an independent predictor of long-term mortality in Chinese PD patients. | 23391316 |
| Inflammation, Calcinosis, Atherosclerosis, Aortic Valve Stenosis | Altered Intercellular Communication | Aortic stenosis, atherosclerosis, and skeletal bone: is there a common link with calcification and inflammation? | 23391586 |
| Inflammation, Aortic valve calcification, Atherosclerosis | Altered Intercellular Communication | Using non-invasive imaging, we compared aortic valve calcification and inflammation activity with that measured in atherosclerosis and bone. | 23391586 |
| Acute and chronic inflammation | Altered Intercellular Communication | Subsequent increases in biliary leaks might contribute to the pathogenesis of chronic biliary inflammation in these patients. | 23391819 |
| Mastitis, Inflammation | Altered Intercellular Communication | Of the 51 cases with non-puerperal mastitis, 94.1% (48/51) were confirmed as having acute or chronic inflammation, and the other 3 had plasma cell mastitis; areola papillaris inflammation was found in 39.2% (20/51) of the cases. | 23392197 |
| Inflammation, Primary malignant neoplasm | Altered Intercellular Communication | Reduction of inflammation should theoretically reduce the development of cancer. | 23392347 |
| Hypoalbuminemia | Altered Intercellular Communication | The Glasgow Prognostic Score (GPS), which is an inflammation-based prognostic factor, is defined by the presence of elevated C-reactive protein and hypoalbuminemia. | 23392422 |
| Inflammation, Chronic Obstructive Airway Disease | Altered Intercellular Communication | Clusters of comorbidities based on validated objective measurements and systemic inflammation in patients with chronic obstructive pulmonary disease. | 23392440 |
| ARCN1 gene, Inflammation | Altered Intercellular Communication | The coexistence of objectively identified comorbidities and the role of low-grade systemic inflammation in the pathophysiology of COPD remain to be elucidated. | 23392440 |
| Inflammation | Altered Intercellular Communication | To cluster 13 clinically important objectively identified comorbidities, and to characterize the comorbidity clusters in terms of clinical outcomes and systemic inflammation. | 23392440 |
| methyldopa, Inflammation | Altered Intercellular Communication | This information might shed light on underlying pathological mechanisms involving inflammation and could be of clinical utility in the identification of persons at high risk of AMD who may benefit from increased adherence to lifestyle recommendations, eye examination schedules, and therapeutic protocols. | 23392454 |
| Inflammation | Altered Intercellular Communication | IL-34 seems to be involved in the pathogenesis of salivary gland inflammation in p-SS. | 23392590 |
| Paraneoplastic Syndromes, Osteomalacia, Hypophosphatemia | Altered Intercellular Communication | Oncogenic osteomalacia, a paraneoplastic syndrome associated with hypophosphatemia due to increased urinary phosphate excretion, is caused by excessive synthesis and secretion of fibroblast growth factor 23 (FGF23), a phosphaturic hormone that is normally produced by osteocytes. | 23393166 |
| Inflammation, Chronic Kidney Diseases, Cardiovascular Diseases | Altered Intercellular Communication | Elevated serum uric acid has been associated with a variety of cardiovascular disease and with inflammation, but these have been little explored in chronic kidney disease (CKD). | 23394103 |
| HD Term Type, Inflammation, Atherosclerosis | Altered Intercellular Communication | These original data suggest that uric acid may have a role in inflammation and atherosclerosis in HD patients. | 23394103 |
| Eosinophilic inflammation | Altered Intercellular Communication | Suppression of mucosal eosinophilic inflammation is one of the pathways by which PLK DS improves pollinosis-induced nasal obstruction. | 23394502 |
| Inflammation, Aortic Aneurysm, Abdominal | Altered Intercellular Communication | 4D-PET/CT with [(11)C]-PK11195 and [(11)C]-(D)-deprenyl does not identify the chronic inflammation in asymptomatic abdominal aortic aneurysms. | 23394769 |
| APP gene, Inflammation, Aortic Aneurysm, Abdominal | Altered Intercellular Communication | The aim of this study was to investigate the relevance of inflammation in the pathogenesis of abdominal aortic aneurysm (AAA) in vivo with two novel positron emission tomography (PET) tracers: [(11)C]-PK11195 which targets the translocator protein (18 kDa) expressed on macrophages and [(11)C]-d-deprenyl with a yet unknown target receptor expressed in chronic inflammation. | 23394769 |
| Inflammation | Altered Intercellular Communication | The chronic inflammation observed in the vessel wall was not detectable with [(11)C]-PK11195 and [(11)C]-d-deprenyl. | 23394769 |
| Granulomatous inflammation | Altered Intercellular Communication | B. pseudomallei was isolated from purulent material, and histologic examination revealed granulomatous inflammation. | 23395629 |
| Granulomatous inflammation, Melioidosis | Altered Intercellular Communication | The present case highlights the need for an awareness of melioidosis as a new differential diagnosis for a nontuberculous, granulomatous inflammation in those living in or visiting tropical regions. | 23395629 |
| Inflammation, Diabetes Mellitus, Non-Insulin-Dependent | Altered Intercellular Communication | Hepatic insulin resistance is a driving force in the pathogenesis of type 2 diabetes mellitus (T2DM) and is tightly coupled with excessive storage of fat and the ensuing inflammation within the liver. | 23396210 |
| Inflammation | Altered Intercellular Communication | Adiposity and fat distribution in relation to inflammation and oxidative stress in a relatively lean population of Chinese women. | 23396296 |
| Inflammation, Cirrhotic, Peritoneal Fluid (body substance) | Altered Intercellular Communication | Mean platelet volume is a useful indicator of systemic inflammation in cirrhotic patients with ascitic fluid infection. | 23396741 |
| Inflammation, Intestinal Microbiome | Altered Intercellular Communication | Biomarkers of chemotherapy-induced diarrhoea: a clinical study of intestinal microbiome alterations, inflammation and circulating matrix metalloproteinases. | 23397098 |
| Inflammation | Altered Intercellular Communication | Patients clinically responding to biologics might still have the potential of moderate/severe local joint inflammation, composed in particular of and possibly driven by the autoinflammatory TLR(+) cells. | 23397147 |
| Inflammation, Structure of beta Cell of islet, Diabetes Mellitus, Non-Insulin-Dependent, Abnormality of mitochondrial metabolism | Altered Intercellular Communication | As chronic inflammation and mitochondrial dysfunction are key factors mediating pancreatic beta cell impairment in type 2 diabetes, we investigated the role of SIRT3 in the maintenance of beta cell function and mass in type 2 diabetes. | 23397292 |
| Inflammation, Obesity | Altered Intercellular Communication | Increased production of chemokines by adipose tissue and defective adipose tissue oxygenation as a result of obesity may induce leucocyte infiltration and subsequent systemic inflammation. | 23398210 |
| Anxiety, CTCAE 3.0, Inflammation, Neurobehavioral Manifestations, Depression, CTCAE | Altered Intercellular Communication | Differential association of somatic and cognitive symptoms of depression and anxiety with inflammation: findings from the Netherlands Study of Depression and Anxiety (NESDA). | 23399050 |
| Anxiety, CTCAE 3.0, Inflammation, Depression, CTCAE | Altered Intercellular Communication | Depression and anxiety have been suggested to be associated with systemic inflammation upregulation. | 23399050 |
| Inflammation, Medically Unexplained Symptoms, Anxiety, CTCAE 3.0, Depression, CTCAE | Altered Intercellular Communication | There are some indications that associations with inflammation are mainly driven by somatic symptoms of depression and anxiety. | 23399050 |
| Anxiety, CTCAE 3.0, Inflammation, Neurobehavioral Manifestations, Depression, CTCAE | Altered Intercellular Communication | We therefore set out to evaluate the differential association of somatic and cognitive symptoms of depression and anxiety with inflammation, while adjusting for demographic, health related, and lifestyle related variables. | 23399050 |
| Anxiety, CTCAE 3.0, Medically Unexplained Symptoms, Inflammation, Depression, CTCAE | Altered Intercellular Communication | Especially somatic symptoms of depression and anxiety are associated with inflammation. | 23399050 |
| Inflammation, Fibrosis Assessment, Injury of kidney | Altered Intercellular Communication | Activation of the CD40 receptor on the proximal tubular epithelium of the kidney results in fibrosis and inflammation in experimental models of kidney injury. | 23399713 |
| Inflammation, Periodontal Diseases | Altered Intercellular Communication | In vivo inflammation mapping of periodontal disease based on diffuse reflectance spectral imaging: a clinical study. | 23400418 |
| Inflammation, GDC Disease Response Terminology | Altered Intercellular Communication | The DR image ratio R620/R575 computed for each pixel (8-um resolution) from the monochrome images is pseudo-color-mapped to identify gingival inflammation sites. | 23400418 |
| Inflammation, GDC Disease Response Terminology | Altered Intercellular Communication | The DR image ratio values at each site are compared with clinical diagnosis to estimate the specificity and sensitivity of the DR imaging technique in inflammation mapping. | 23400418 |
| Inflammation, Periodontitis | Altered Intercellular Communication | The high diagnostic accuracy is utilized to detect underlying inflammation in six patients with a previous history of periodontitis. | 23400418 |
| Inflammation | Altered Intercellular Communication | Diffuse large B-cell lymphoma associated with chronic inflammation in metallic implant. | 23401446 |
| Chronic heart failure, Impaired exercise tolerance | Altered Intercellular Communication | Hormonal imbalance in relation to exercise intolerance and ventilatory inefficiency in chronic heart failure. | 23402947 |
| Inflammation, physiopathological, SMAD1 protein, human | Altered Intercellular Communication | Our study suggests that skin inflammation reduces the expression of FLG-like proteins, contributing to the AD-related epidermal barrier dysfunction. | 23403047 |
| Inflammation, Cholestasis, Necrosis | Altered Intercellular Communication | A variety of non-specific features such as fatty change, mild inflammation, cholestasis and focal necrosis were seen in the other UCD patients. | 23403242 |
| Behavioral and psychological symptoms of dementia, Inflammation, "Alzheimers Disease | Altered Intercellular Communication | Biomarkers of vascular risk, systemic inflammation, and microvascular pathology and neuropsychiatric symptoms in Alzheimer's disease. | 23403534 |
| Inflammation, "Alzheimers Disease", Mental disorders, Data types - Address | Altered Intercellular Communication | Numerous serum and plasma based biomarkers of systemic inflammation have been linked to both neuropsychiatric disorders and Alzheimer's disease (AD). | 23403534 |
| Behavioral and psychological symptoms of dementia, Inflammation, Mental disorders, Data types - Address | Altered Intercellular Communication | A combination of biomarkers of systemic inflammation, microvascular pathology, and clinical biomarkers of cardiovascular risk can account for a significant portion of the variance in the occurrence of neuropsychiatric symptoms in AD supporting a vascular and inflammatory component of psychiatric disorders found in AD. | 23403534 |
| Helicobacter pylori, Gastritis | Altered Intercellular Communication | LAB extracts could inhibit the bacterial adhesion and invasion, gastric inflammation and DNA fragmentation induced by Helicobacter pylori. | 23404362 |
| Parkinson Disease, Inflammation, "Alzheimers Disease", Nervous system problem | Altered Intercellular Communication | Literature indicated that chronic inflammation might be a factor in developing neurological problems, including Alzheimer's, Parkinson's and other similar illnesses. | 23404438 |
| Inflammation, "Alzheimers Disease | Altered Intercellular Communication | Escalated levels of monocytes and neutrophils are hallmarks of chronic inflammation and may be precursor to Alzheimer's disease. | 23404438 |
| Inflammatory, Communicable Diseases | Altered Intercellular Communication | A low lymphocyte count specifies that the body's resistance to fight infection is substantially reduced, whereas low basophil levels indicates their over utilization due to chronic allergic inflammatory condition. | 23404438 |
| Inflammation, Obesity, Bipolar Disorder | Altered Intercellular Communication | Longitudinal associations between obesity, inflammation, and depressive symptoms amongst a cohort of older English adults over 4 years of follow-up were examined. | 23404927 |
| Inflammation, Obesity, Bipolar Disorder | Altered Intercellular Communication | These data suggest that chronic inflammation may be a key determinant of depressive symptoms in obesity. | 23404927 |
| Pain Distress Question, Inflammation | Altered Intercellular Communication | Expression level of signaling effectors was similar in control and diseased patients and did not correlate with measures of pain and inflammation. | 23404938 |
| Inflammation, Endothelial dysfunction | Altered Intercellular Communication | High fat meal challenges are known to induce postprandial low-grade inflammation and endothelial dysfunction. | 23405070 |
| Tumor necrosis, Inflammation, Neoplasms | Altered Intercellular Communication | Thalidomide is a tumor necrosis factor alpha (TNFa) inhibitor which has been found to have abilities against tumor growth, angiogenesis and inflammation. | 23405115 |
| Sepsis, Inflammation, Fever, CTCAE, Suprapubic pain | Altered Intercellular Communication | We report the case of a 55-year-old woman who presented at the emergency department with hypogastric pain, fever, clinical signs of sepsis and a critical inflammation syndrome in her blood test values. | 23405485 |
| Acute Coronary Syndrome, vascular inflammations, GDC AJCC Clinical Stage Terminology | Altered Intercellular Communication | Vascular inflammation plays a key role in the development of acute coronary syndrome (ACS). | 23406538 |
| Inflammation | Altered Intercellular Communication | Pregnancy-associated plasma protein A (PAPP-A) and calprotectin are two of several novel promising markers of inflammation. | 23406538 |
| Inflammation | Altered Intercellular Communication | Plasma PON1 and TOS levels may serve as predictors of disease severity in children with AR and both of them appear to be attractive candidates for modulating inflammation in AR. | 23406590 |
| Erythema Multiforme, Inflammation, Fever, CTCAE | Altered Intercellular Communication | We report on the case of a 4 years old boy presenting high-grade fever associated with erythema multiforme and evidence of systemic inflammation who showed a good response to prompt treatment with intravenous immunoglobulins. | 23406772 |
| Bronchial Hyperreactivity, Airway structure, Chest tightness, Wheezing, Dyspnea | Altered Intercellular Communication | Asthma has been defined as a disease of chronic airway inflammation in which many cells and cellular products participate with variable degrees of airflow obstruction and hyperresponsiveness that lead to recurrent episodes of wheezing, breathlessness, chest tightness, and coughing. | 23406941 |
| Inflammation, Infiltration | Altered Intercellular Communication | All eyes showed mild stromal infiltration a few days after the procedure; however, the inflammation was resolved within 1 week. | 23407323 |
| Inflammation | Altered Intercellular Communication | Postoperative inflammation may play a crucial role in its pathogenesis. | 23407323 |
| Neoplasms | Altered Intercellular Communication | Whereas early surgical resection can significantly reduce tumor mass, there are few data available concerning the control of hormonal secretion and associated symptoms. | 23407483 |
| Inflammation, Coronary Artery Disease | Altered Intercellular Communication | Reduced antiplatelet effect of aspirin is associated with low-grade inflammation in patients with coronary artery disease. | 23407706 |
| Inflammation | Altered Intercellular Communication | NFkB as a potent regulator of inflammation in human adipose tissue, influenced by depot, adiposity, T2DM status, and TNFa. | 23408599 |
| Inflammation, Obesity | Altered Intercellular Communication | Central obesity and sub-clinical inflammation increase metabolic risk, this study examined the intracellular inflammatory pathways in adipose tissue (AT) that contribute to this risk. | 23408599 |
| Inflammation, Joint swelling, Joint tenderness | Altered Intercellular Communication | In the first year, patients with a high BMI had higher DAS and worse functional ability, with more tender joints and a higher visual analog scale global health, but not more swollen joints and similar systemic inflammation. | 23408767 |
| Pain Distress Question, Swelling, Inflammation | Altered Intercellular Communication | Patients with a high BMI experienced more pain, but not more swelling or systemic inflammation. | 23408767 |
| Pneumonitis | Altered Intercellular Communication | Overexpression of ApoA1 decreased silica-induced lung inflammation and fibrotic nodule formation. | 23409054 |
| Inflammation, Pain Distress Question, Poland Syndrome, Bursitis, Hypertrophy | Altered Intercellular Communication | Haglund's syndrome, which is an inflammation of the bursa and a bony enlargement on the back of the heel that most often leads to painful bursitis, is a rare cause of retrocalcaneal pain. | 23409529 |
| Inflammation, Muscular Dystrophy, Facioscapulohumeral | Altered Intercellular Communication | Muscle regeneration and inflammation in patients with facioscapulohumeral muscular dystrophy. | 23410246 |
| Inflammation, Muscle (organ) | Altered Intercellular Communication | Inflammation in muscle has been suggested by MRI studies in patients with FSHD1A. | 23410246 |
| Inflammation, Sleep Apnea, CTCAE, Hypoxia | Altered Intercellular Communication | Patients with sleep apnea sustain cessation of breath during sleep, leading to intermittent hypoxia, systemic inflammation, and sympathetic activation. | 23410566 |
| Inflammation | Altered Intercellular Communication | These results provide evidence that glucose ingestion affects systemic inflammation and oxidative stress. | 23410727 |
| Communicable Diseases, Myelitis, Myelitis, Transverse | Altered Intercellular Communication | Transverse myelitis is diagnosed based on the presence of spinal cord inflammation and the absence of infection to the central nervous system. | 23411769 |
| Inflammation | Altered Intercellular Communication | At autopsy the most important changes in the brain were focal sub cortical peri-vascular mononuclear inflammation of the cerebral vessels. | 23412045 |
| Inflammation | Altered Intercellular Communication | Chronic inflammation can be the cause of development of SCC. | 23412122 |
| ARCN1 gene, Inflammation | Altered Intercellular Communication | This novel type of immune remodelling, which predicts an increased capacity to respond to alveolar antigens, is suggested to contribute to aggravated inflammation in COPD. | 23412435 |
| Crohn Disease, Inflammation, Granuloma | Altered Intercellular Communication | Crohn's disease was characterized by transmural inflammation and epithelioid granulomas. | 23412670 |
| Inflammation, Chronic Kidney Diseases | Altered Intercellular Communication | The relationship between psychological factors, inflammation, and nutrition in patients with chronic renal failure undergoing hemodialysis. | 23413658 |
| melanoma | Altered Intercellular Communication | The significance of sarcoidal-type inflammation occurring during treatment of metastatic melanoma with a combination of BRAF and MEK inhibitors is unclear. | 23413975 |
| Granulomatous inflammation, Sarcoidosis, Eosinophilic granulomatosis with polyangiitis, Vasculitis, CTCAE | Altered Intercellular Communication | Although scar sarcoidosis is a well-described phenomenon, granulomatous inflammation and vasculitis seen in Churg-Strauss syndrome exclusively manifesting in well-healed surgical scars highlights the unique features seen in this case and draws attention to the concept of locus minoris resistentiae. | 23414289 |
| Granulomatous inflammation, Vasculitis, CTCAE | Altered Intercellular Communication | This case also highlights how a skin biopsy in the setting of suspected systemic vasculitis can confirm the presence of vasculitis and/or granulomatous inflammation and obviate the need for more invasive, higher risk procedures such as lung biopsy. | 23414289 |
| Inflammation | Altered Intercellular Communication | CRP is synthesized in the liver and may represent a systemic response to local inflammation. | 23414296 |
| Inflammation, Vascular System Injuries | Altered Intercellular Communication | PTX3 is synthesized locally at the inflammatory sites and may represent a marker for local inflammation at sites of vessel injury. | 23414296 |
| Airway structure, Asthma | Altered Intercellular Communication | In this prospective study in a preschool children cohort, we assessed whether the fraction of exhaled nitric oxide (FeNO), a biomarker of airway inflammation, is associated with asthma at school age. | 23414302 |
| Inflammation, Impaired cognition, Cardiovascular Diseases | Altered Intercellular Communication | Inflammation is involved in the pathogenesis of cardiovascular disease and cognitive decline. | 23414490 |
| Liver Cirrhosis | Altered Intercellular Communication | Liver biopsy was performed in 31.22%; varying grades of inflammation-fibrosis were found in 63.51% and cirrhosis was found in 12.84%. | 23414836 |
| Inflammation, Granulation finding | Altered Intercellular Communication | In all inflammation and granulation tissue developed over the stents, but this could be managed by scraping or balloon compression. | 23414854 |
| Sepsis, Inflammation | Altered Intercellular Communication | Elevated biomarkers of inflammation and endothelial cell activation have been associated with severity of sepsis. | 23414982 |
| Inflammation, Observation Method - Coagulation, Vascular System Injuries | Altered Intercellular Communication | Recent evidence suggests that circulating microparticles (MPs) contribute to inflammation, coagulation and vascular injury. | 23415055 |
| Minimal Disseminated Disease, Depressive disorder | Altered Intercellular Communication | Norepinephrine and glutamate are among several neurotransmitters implicated in the neuropathology of major depressive disorder (MDD). | 23415275 |
| Inflammation, Atherosclerosis | Altered Intercellular Communication | Risk factors for atherosclerosis may contribute to chronic low-grade inflammation. | 23416719 |
| Granulomatosis with polyangiitis | Altered Intercellular Communication | Wegener's granulomatosis is an uncommon multi-systemic disease characterized by necrotizing granulomatous inflammation of the upper and lower respiratory tracts and general focal necrotizing vasculitis (commonly known as Wegener's triad). | 23416832 |
| Inflammation, Irritable Bowel Syndrome | Altered Intercellular Communication | Low-grade inflammation in the rectum of patients with sporadic irritable bowel syndrome. | 23417076 |
| Ichthyosis Bullosa of Siemens | Altered Intercellular Communication | However, intestinal low-grade inflammation has been proposed as one of the factors contributing to the development of IBS. | 23417076 |
| Inflammation, Ichthyosis Bullosa of Siemens | Altered Intercellular Communication | These findings oppose low-grade inflammation as a pathogenic factor in sporadic IBS. | 23417076 |
| Inflammation, Ichthyosis Bullosa of Siemens, Post-infectious disorder | Altered Intercellular Communication | Low-grade inflammation may, however, play an important role in the pathogenesis of a subset of IBS, namely post-infectious IBS (PI-IBS). | 23417076 |
| Granulomatous inflammation, Sarcoidosis | Altered Intercellular Communication | The histopathological examination of the right testis and lung biopsy revealed granulomatous inflammation consistent with sarcoidosis. | 23417949 |
| Inflammation, Respiratory Distress Syndrome, Newborn, Pneumonia, Viral, Influenza | Altered Intercellular Communication | It is postulated that excess inflammation and cytokine production in obese patients following severe influenza infection leads to viral pneumonitis and/or acute respiratory distress syndrome. | 23418448 |
| palladium, Inflammation, Fibrosis Assessment, Elastosis perforans serpiginosa | Altered Intercellular Communication | Encapsulating peritoneal sclerosis (EPS) is a devastating complication of peritoneal dialysis (PD), characterized by marked inflammation and severe fibrosis of the peritoneum, and associated with high morbidity and mortality. | 23418565 |
| Airway structure, Asthma | Altered Intercellular Communication | Aberrant apoptosis in asthma contributes to airway inflammation. | 23418891 |
| Airway structure | Altered Intercellular Communication | Early apoptosis and fragility of airway epithelial cells and delayed apoptosis of inflammatory lymphocytes can cooperate to increase airway inflammation. | 23418891 |
| Autoimmune Diseases, Polyarteritis Nodosa, Inflammation | Altered Intercellular Communication | Classical polyarteritis nodosa (cPN) is a rare autoimmune disease featuring systemic inflammation of middle- and small-sized arteries. | 23419691 |
| Inflammation, Frontotemporal Lobar Degeneration | Altered Intercellular Communication | Leukocytes mRNA levels of TMEM40 and LY6G6F and other genes mainly involved in inflammation were significantly higher in patients carrying GRN mutations compared with asymptomatic carriers and other FTLD. | 23419701 |
| Inflammation, Nerve Degeneration | Altered Intercellular Communication | Enhanced inflammation associated with the onset of GRN disease might be either related to disease pathogenetic mechanism leading to neurodegeneration or to a compensatory pathway that counteracts disease progression. | 23419701 |
| Inflammation, Malignant Neoplasms | Altered Intercellular Communication | The endoscopic features of these cancers may be modified by controlling inflammation. | 23420575 |
| Granulomatous inflammation, Necrotizing Arteritis, Exudate | Altered Intercellular Communication | Fourteen patients had granulomatous inflammation surrounding a central necrotizing eosinophilic exudate identified in surgical pathology specimens from abdominal surgeries. | 23421741 |
| Folliculitis | Altered Intercellular Communication | Current evidence indicates that hair follicle inflammation in AA is caused by a T-cell-mediated autoimmune mechanism occurring in genetically predisposed individuals. | 23422615 |
| Inflammation, Edema, Urinary Bladder Fistula | Altered Intercellular Communication | Lack of the prominent inflammation and edema that characterizes both papillary and polypoid cystitis, and absence of a history of recent bladder catheterization and presence of vesical fistula may facilitate the decision to biopsy the lesion. | 23423685 |
| Degenerative polyarthritis, Inflammation | Altered Intercellular Communication | This study suggests a rapid slowdown of type II collagen degradation and joint inflammation after VS with Hylan G-20 and gives additional information for the validation of accurate biomarkers for OA. | 23423846 |
| Neoplasms | Altered Intercellular Communication | The Glasgow Prognostic Score (GPS), an inflammation-based prognostic score including C-reactive protein and albumin, shows significant prognostic value in several types of solid tumors. | 23423859 |
| Paranasal Sinus Disorder, Inflammation | Altered Intercellular Communication | CT of the head indicated sinus disease including mucoperiosteal-like thickening of the right maxillary sinus, left mastoid hypoaeration and sclerosis characteristics of chronic inflammation. | 23424778 |
| Inflammatory disease of mucous membrane | Altered Intercellular Communication | In this cohort of SBCD patients, clinical disease activity index was not reliable predictors of mucosal inflammation. | 23425203 |
| Inflammation, Neoplasm Metastasis, Neoplasms | Altered Intercellular Communication | They play an important role in normal tissue remodelling and growth, as well as in many destructive pathological conditions such as inflammation, tumour growth and metastasis. | 23425881 |
| Pulpitis | Altered Intercellular Communication | This investigation opens a new opportunity for one contemporary method for the diagnosis of pulp inflammations and monitoring of the inflammatory processes. | 23425881 |
| Inflammation, Hypertensive (finding), Metabolic Syndrome X | Altered Intercellular Communication | Irbesartan appears to exert beneficial effects on oxidative stress, inflammation, lipid metabolism and metabolic syndrome, indicating that it may be useful in high-risk hypertensive patients. | 23425956 |
| Colorectal Carcinoma | Altered Intercellular Communication | Inflammation underlies the etiology of colorectal cancer (CRC). | 23426034 |
| Inflammation, Hyperhomocysteinemia, Colorectal Carcinoma | Altered Intercellular Communication | Hyperhomocysteinemia is associated with inflammation and may be a risk marker for CRC. | 23426034 |
| Inflammation, Diverticulitis | Altered Intercellular Communication | Patients taking mesalazine have lower risk of diverticulitis recurrence than patients taking rifaximin because of the lower prevalence of persisting endoscopic and histological inflammation. | 23426537 |
| Inflammation, Familial Mediterranean Fever | Altered Intercellular Communication | Endogenous anti-oxidants Paraoxonase 1 and arylesterase levels are important in evaluating the inflammation at the remission period of FMF. | 23426541 |
| Inflammation, Ulcerative Colitis | Altered Intercellular Communication | In contrast, mucus on colon biopsy specimens from patients with UC with acute inflammation was highly penetrable. | 23426893 |
| Refractory anemias, Inflammation, Autoimmune Diseases | Altered Intercellular Communication | These results suggest that in patients with active RA, CD19(+)CD24(hi)CD38(hi) B cells with regulatory function may fail to prevent the development of autoreactive responses and inflammation, leading to autoimmunity. | 23427243 |
| Tissue Adhesions, Carcinoma of lung, Pneumonitis | Altered Intercellular Communication | Severe adhesions and lung inflammation are conditions that make lung cancer surgery difficult; a skillful and meticulous surgical technique is required in elderly patients. | 23427311 |
| Inflammation, Cerebral Aneurysm | Altered Intercellular Communication | The findings provide radiographic evidence of decreased inflammation in human cerebral aneurysms with daily intake of aspirin using macrophages as a surrogate marker for inflammation. | 23428244 |
| Inflammation, Fibrosis Assessment | Altered Intercellular Communication | Our new method seems promising since it has the ability to diagnose fibrosis even in the presence of inflammation. | 23428852 |
| Inflammation | Altered Intercellular Communication | Atypical presentation of tracheobronchopathia osteochondroplastica: is chronic inflammation a perpetrator? | 23428943 |
| Macular Edema, Cystoid, Inflammatory abnormality of the eye | Altered Intercellular Communication | Bromfenac sodium 0.1%, fluorometholone 0.1% and dexamethasone 0.1% for control of ocular inflammation and prevention of cystoid macular edema after phacoemulsification. | 23429038 |
| Macular Edema, Cystoid, Acute inflammation | Altered Intercellular Communication | To compare bromfenac sodium 0.1%, fluorometholone 0.1% and dexamethasone 0.1% for the control of postoperative inflammation and prevention of cystoid macular edema (CME) after phacoemulsification. | 23429038 |
| Inflammatory abnormality of the eye | Altered Intercellular Communication | Bromfenac sodium cleared the ocular inflammation more rapidly than fluorometholone and dexamethasone. | 23429038 |
| Inflammation | Altered Intercellular Communication | However, modified or oxidized albumin may lead to a cycle of accelerated oxidative stress and inflammation involving neutrophil activation. | 23429046 |
| Inflammation, Thrombosis, Coronary Artery Disease | Altered Intercellular Communication | Inflammation is implicated in the progression of coronary artery disease and the molecular processes of inflammation and thrombosis are closely intertwined. | 23429252 |
| Acute and chronic inflammation, Ulcerative Colitis | Altered Intercellular Communication | Chronic pouch inflammation and risk for new-onset extraintestinal cancers in patients with restorative proctocolectomy for ulcerative colitis. | 23429461 |
| Inflammation, Intestinal Cancer, Colitis | Altered Intercellular Communication | In the logistic regression model, older age (odds ratio [OR] = 1.5; 95% CI, 1.2-1.8), left-sided colitis (OR = 12.3; 95% CI, 2.2-67.8), and chronic pouch inflammation (OR = 4.4; 95% CI, 1.5-12.9) were associated with the risk for extraintestinal cancer. | 23429461 |
| Inflammation, Intestinal Cancer | Altered Intercellular Communication | Older age and chronic pouch inflammation may be associated with an increased risk for extraintestinal cancer in this cohort. | 23429461 |
| Inflammatory abnormality of the eye, Biocompatibility | Altered Intercellular Communication | The allografts were stable and biocompatibile in all 10 cases during the follow-up period, evidenced by maintained clarity of the corneal tissue, absence of clinical signs of immunologic rejection or ocular inflammation, and integrity of the sterile cornea and the conjunctiva over the graft. | 23429612 |
| Inflammation, Hemorrhage, Pathologic Neovascularization | Altered Intercellular Communication | Pericardioscopy excluded protrusions, petechial bleeding, neovascularization or inflammation. | 23430127 |
| Inflammation, Chronic Kidney Diseases, Coronary heart disease | Altered Intercellular Communication | ALP but not serum phosphate was associated with increased risk of coronary heart disease and overall CVD events which persisted after adjustment for CVD risk factors and markers of inflammation and after exclusion of men with chronic kidney disease (adjusted hazard ratio per SD, 1.19 [1.05, 1.34]; P=0.007 and 1.10 [1.01, 1.21]; P=0.04). | 23430618 |
| Inflammation, Autoimmune Lymphoproliferative Syndrome Type 2B | Altered Intercellular Communication | Inflammation is clearly involved in the pathogenesis of DEDs, and there is mounting evidence on the antioxidant and antiinflammatory properties of essential polyunsaturated fatty acids (EPUFAs). | 23430672 |
| Kidney Failure, Chronic, Inflammation, Uremia, Atherosclerosis | Altered Intercellular Communication | In summary, serum PBHCit, a footprint of protein carbamylation, predicts increased cardiovascular risk in patients with ESRD, supporting a mechanistic link among uremia, inflammation, and atherosclerosis. | 23431074 |
| Carcinogenesis, Stomach Carcinoma, Gastritis | Altered Intercellular Communication | These results have provided evidence that galectin-1 and mainly annexin-A1 are overexpressed in both gastritis and gastric cancer, suggesting a strong association of these proteins with chronic gastric inflammation and carcinogenesis. | 23431236 |
| Inflammation, Bacterial Infections, Liver Dysfunction, Liver Cirrhosis | Altered Intercellular Communication | Circulating suPAR levels were increased in patients with decompensated cirrhosis and correlated with the severity of liver dysfunction and systemic inflammation but were not indicative of bacterial infection. | 23432143 |
| Crohn Disease, Inflammation | Altered Intercellular Communication | While the Crohn's disease activity index (CDAI) is the gold standard for defining clinical endpoints in Crohn's disease (Crohn's) clinical trials, its ability to distinguish symptoms due to inflammation from those that are non-inflammatory has been questioned. | 23432394 |
| Tracheitis | Altered Intercellular Communication | This minimised tracheal inflammation and granulation tissue formation. | 23433096 |
| Inflammation, Neoplasms | Altered Intercellular Communication | Histological diagnosis of the facial nerve tumor was IPT probably caused by chronic external ear inflammation induced by epidermal nevi. | 23433476 |
| Rheumatoid Arthritis, vascular inflammations, Coronary Artery Disease | Altered Intercellular Communication | The aims were to evaluate the presence and extent of pentraxin 3 depositions in specimens from the outer layers of the aorta and from the internal thoracic artery of patients with coronary artery disease with and without rheumatoid arthritis and to search for relationships between pentraxin 3 and vascular inflammation. | 23434196 |
| Inflammation | Altered Intercellular Communication | Pentraxin 3 depositions in the outer aortic layers are common and are related to the local inflammation. | 23434196 |
| Inflammation, Fibrosis Assessment | Altered Intercellular Communication | Chronic inflammation around nerve bundles, sclerotic fibrosis, and prominent lymphoid follicles with plasma cells were the main features of the mass. | 23434261 |
| Diabetic Nephropathy | Altered Intercellular Communication | Tubulointerstitial inflammation plays a key role in the development of diabetic nephropathy (DN). | 23434541 |
| Interstitial inflammation | Altered Intercellular Communication | We investigated the role of ATP-P2X4 signaling in NLRP3 inflammasome activation and renal interstitial inflammation characteristic of DN. | 23434541 |
| Hypercalcemia, CTCAE, Neoplasms | Altered Intercellular Communication | On the basis of severe hypercalcemia (serum calcium 3.66 mmol/l) and high serum parathyroid hormone level (162.5 pmol/l) the diagnosis of a right sided parathyroid tumour was established. | 23434885 |
| Inflammation, Demographics Domain | Altered Intercellular Communication | The pathogenesis of skin inflammation in DM is not well understood. | 23434970 |
| Inflammation, Fibrosis Assessment, Anastomosis - action, Pancreatic duct, Pancreatic Anastomotic Leakage | Altered Intercellular Communication | Invagination with duct-to-mucosa anastomosis is a useful technique to prevent pancreatic leakage; however, it is difficult to prevent inflammation and fibrosis around the anastomotic site of PG, and this can lead to anastomotic stricture in patients with a remarkably dilated pancreatic duct (diameter >=7 mm). | 23435147 |
| Vitreous inflammatory cells | Altered Intercellular Communication | Vitreous inflammation scores at baseline and at 1 year were statistically significantly reduced in both eyes (p<0.001; p=0.001). | 23435191 |
| Inflammation, Kaposi Sarcoma | Altered Intercellular Communication | We compared markers of immunosenescence, naive T cells, activation, and inflammation in CD4+ and CD8+ T cells from antiretroviral-treated participants with new-onset Kaposi's sarcoma (cases, n = 19) and from treated individuals without Kaposi's sarcoma (controls, n = 47). | 23435301 |
| Inflammation, Hypertension, CTCAE | Altered Intercellular Communication | Insulin resistance, inflammation and oxidative stress (OS), are among the mechanisms that have been implicated in pathogenesis of essential hypertension (EH). | 23435396 |
| ANOPHTHALMIA AND PULMONARY HYPOPLASIA, Pancreatitis, Pancreatic Ductal Adenocarcinoma | Altered Intercellular Communication | Chronic localized pancreatic inflammation in the form of chronic pancreatitis is an established risk factor for human pancreatic ductal adenocarcinoma (PDAC) development. | 23435739 |
| Malignant Neoplasms | Altered Intercellular Communication | Constitutive activation of inflammation-related signal transducer and activator of transcription (Stat)3 signaling has been implicated in the development and progression a number of malignancies, including PDAC. | 23435739 |
| Orbital Pseudotumor | Altered Intercellular Communication | Idiopathic orbital inflammation syndrome with retro-orbital involvement: a retrospective study of eight patients. | 23437329 |
| Orbital Pseudotumor | Altered Intercellular Communication | Seventy-three patients were diagnosed with idiopathic orbital inflammation syndrome based on clinicoradiological features, with pathological confirmation of nonspecific inflammatory conditions in 47 patients. | 23437329 |
| Cephalometric orbitale point, Orbital Pseudotumor | Altered Intercellular Communication | All 8 patients were diagnosed with idiopathic orbital inflammation syndrome after biopsy of the orbital lesion. | 23437329 |
| Inflammation | Altered Intercellular Communication | In all 8 patients with retro-orbital involvement, the inflammation spread through the superior orbital fissure. | 23437329 |
| Inflammation, Orbital Pseudotumor | Altered Intercellular Communication | The diffuse inflammation with marked sclerosis and hyalinization that we observed in the patients with retro-orbital involvement is consistent with the diagnosis of the sclerosing subtype of idiopathic orbital inflammation syndrome. | 23437329 |
| Orbital Pseudotumor | Altered Intercellular Communication | In patients with idiopathic orbital inflammation syndrome, it is important to perform MRI and CT scans to identify possible retro-orbital involvement. | 23437329 |
| Orbital Pseudotumor | Altered Intercellular Communication | Seventy-three patients were diagnosed with idiopathic orbital inflammation syndrome based on clinicoradiological features, with pathological confirmation of nonspecific inflammatory conditions in 47 patients. | 23437329 |
| Inflammation | Altered Intercellular Communication | Characterization of the role of distinct plasma cell-free DNA species in age-associated inflammation and frailty. | 23438186 |
| Inflammation, Cell Death | Altered Intercellular Communication | Plasma cell-free DNA (cf-DNA) has recently emerged as a potential biomarker of aging, reflecting systemic inflammation, and cell death. | 23438186 |
| Inflammation, Immunosenescence | Altered Intercellular Communication | We identified the relationships between these cf-DNA species and age-associated inflammation, immunosenescence, and frailty. | 23438186 |
| Airway structure, Inflammation, Chronic Obstructive Airway Disease, ARCN1 gene | Altered Intercellular Communication | We have suggested that chronic inflammation of other foregut derivatives might be associated with airway inflammation and amplification of the response to inhaled stimuli such as cigarette smoke leading to chronic obstructive pulmonary disease (COPD). | 23438259 |
| Gastritis, Acute and chronic inflammation, Infection caused by Helicobacter pylori | Altered Intercellular Communication | One of the commonest causes of chronic foregut inflammation is gastritis secondary to Helicobacter Pylori infection. | 23438259 |
| Airway structure, Inflammation, Asthma | Altered Intercellular Communication | Systemic inflammation is associated with differential gene expression and airway neutrophilia in asthma. | 23438328 |
| Airway structure, Inflammation, Asthma | Altered Intercellular Communication | Systemic inflammation is reported to be associated with neutrophilic airway inflammation in asthma, but mechanisms underlying this finding are not well understood. | 23438328 |
| Airway structure, Inflammation, Asthma | Altered Intercellular Communication | This study aimed to examine the molecular mechanisms of the airway neutrophilia that are associated with systemic inflammation in asthma. | 23438328 |
| Inflammation | Altered Intercellular Communication | Asthmatics with systemic inflammation (n=18, 36%) had a higher BMI, greater history of cigarette smoking, lower FVC% predicted, and increased sputum neutrophils compared to those without systemic inflammation (n=16, 32%). | 23438328 |
| Airway structure, Inflammation, Asthma | Altered Intercellular Communication | Systemic inflammation was associated with airway neutrophilia in asthma, and was related to a group of differentially expressed genes in the lung involving multiple cytokine pathways. | 23438328 |
| Inflammation | Altered Intercellular Communication | Our findings suggest that targeting systemic inflammation might provide a novel therapeutic strategy for neutrophilic asthma. | 23438328 |
| Inflammation, Pancreatitis | Altered Intercellular Communication | Acute pancreatitis is an initially localized inflammation of the pancreatic gland. | 23438852 |
| Hemorrhage | Altered Intercellular Communication | The concentric alternating zones of hypo/hyper/iso/intensities corresponded to zones of hemorrhage/fibrin-rich necrosis with edema/coagulative compact necrosis/inflammation with foamy histiocytes admixed with hemorrhage forming the outermost zone, respectively. | 23440973 |
| Inflammation, Hypercholesterolemia, Dysglycemia, Electrocardiogram: left ventricle hypertrophy (finding), Kidney Diseases, Hypertension, CTCAE | Altered Intercellular Communication | These associations became non-significant after adjusting for obesity-related conditions (hypertension, dysglycemia, hypercholesterolemia, left ventricular hypertrophy, kidney disease, and inflammation). | 23441088 |
| Airway structure, Allergic asthma, Asthma, Acid reflux | Altered Intercellular Communication | Pattern of airway inflammation and remodelling in mild persistent atopic asthma and in mild persistent asthma related to gastroesophageal reflux. | 23441441 |
| Airway structure, Asthma, Atopy | Altered Intercellular Communication | Atopic GER-related asthma showed two distinct patterns of airway inflammation. | 23441441 |
| Airway structure | Altered Intercellular Communication | The eosinophilic contribution to airway inflammation was systematically prevailing in the former group, such as: EOS = 10.7% +/- 13.4 sd vs 2.0% +/- 2.8 sd, p = 0.001; ECP = 344.9 mcg/l +/- 635.9 sd vs 59.2 mcg/l +/- 75.1 sd, p = 0.001. | 23441441 |
| Inflammation, Neoplasms | Altered Intercellular Communication | NIS expression in salivary glands is decreased during inflammation and tumor formation. | 23441638 |
| Inflammation, Psoriasis | Altered Intercellular Communication | Morphometric study of microvessels, epidermal characteristics and inflammation in psoriasis vulgaris with their correlations. | 23442461 |
| Inflammation, Psoriasis | Altered Intercellular Communication | Vascular proliferation, inflammation and epidermal changes are important features in the pathogenesis of psoriasis. | 23442461 |
| Inflammation, Psoriasis | Altered Intercellular Communication | Inflammation, microvessels and epidermal parameters were assessed in 50 newly diagnosed cases of psoriasis vulgaris (between 01 Nov 2008 and 31 Oct 2011) by morphometry. | 23442461 |
| Inflammation, Psoriasis | Altered Intercellular Communication | It is likely that inflammation is a key factor in the pathogenesis of psoriasis. | 23442461 |
| Inflammation, Asthma | Altered Intercellular Communication | Distribution of sputum cellular phenotype in a large asthma cohort: predicting factors for eosinophilic vs neutrophilic inflammation. | 23442497 |
| Airway structure, Asthma | Altered Intercellular Communication | Phenotyping asthma according to airway inflammation allows identification of responders to targeted therapy. | 23442497 |
| Airway structure, neutrophilic | Altered Intercellular Communication | Eosinophilic (>=3%) and neutrophilic (>=76%) airway inflammation were observed in 46% and 18% of patients respectively. | 23442497 |
| Inflammation, Tumor necrosis | Altered Intercellular Communication | SP suppressed the inflammation marker tumour necrosis factor-a in spleen tissue. | 23442612 |
| Communicable Diseases, Inflammation | Altered Intercellular Communication | These results suggest that major dietary proteins might affect infection and inflammation by L. monocytogenes. | 23442612 |
| Inflammation, Colorectal Carcinoma, Adenoma of large intestine | Altered Intercellular Communication | Given the evidence linking inflammation and colorectal cancer, we sought to determine if plasma endotoxin concentrations are associated with indicators of systemic or local inflammation and colorectal adenomas. | 23442743 |
| FAM126A gene | Altered Intercellular Communication | HCC may play an important role in protecting normal conjunctiva, and regulating inflammatory conditions of the anterior ocular surface. | 23442876 |
| Inflammation, Nerve Degeneration | Altered Intercellular Communication | Inflammation is an important contributor to pediatric and adult neurodegeneration. | 23443029 |
| Inflammation, Impaired cognition, Cerebrovascular accident | Altered Intercellular Communication | Inflammation may contribute to cognitive impairment after stroke. | 23444307 |
| Inflammation, Cerebrovascular accident | Altered Intercellular Communication | We tested whether markers of inflammation, erythrocyte sedimentation rate (ESR), and serum levels of C-reactive protein are associated with reduced hippocampal volume and poor cognitive performance among stroke survivors. | 23444307 |
| Inflammation | Altered Intercellular Communication | ESR remained unchanged in follow-up examinations, suggesting a chronic inflammation background in some patients. | 23444307 |
| skin damage, Inflammation | Altered Intercellular Communication | Exposure to ultraviolet (UV) radiation causes various forms of acute and chronic skin damage, including immunosuppression, inflammation, premature aging and photodamage. | 23445687 |
| Inflammation, Cirrhotic | Altered Intercellular Communication | Peripheral blood was obtained from 22 cirrhotic patients with systemic inflammation, 13 cirrhotic patients without systemic inflammation and 14 healthy controls. | 23446058 |
| Inflammation, Cirrhotic | Altered Intercellular Communication | These findings were most pronounced in cirrhotic patients with systemic inflammation but fell short of reaching statistical significance when comparing against cirrhotic patients without systemic inflammation. | 23446058 |
| Inflammation, Endotoxemia, Liver Cirrhosis | Altered Intercellular Communication | Our data suggest that bacterial translocation, endotoxaemia, inflammation and T cell activation in cirrhosis are accompanied by an increase in circulating anti-inflammatory cytokines, reduced monocytic MHC class II expression and attenuated cytokine production in T cells. | 23446058 |
| Inflammation, Infection | Altered Intercellular Communication | Patients become more susceptible to infections and to lymphoproliferation and granulomatous inflammation. | 23446300 |
| Communicable Diseases, Heart Septal Defects, Inflammation | Altered Intercellular Communication | The authors hypothesized that the patient had enlarged an existing nasal septal defect due to repetitive nose picking resulting in recurrent infection and inflammation of sinuses, leading to erosion of his medial orbital wall. | 23446305 |
| Inflammation, Primary acquired nasolacrimal duct obstruction | Altered Intercellular Communication | Pathological origin of primary acquired nasolacrimal duct obstruction (PANDO) is considered as inflammation of unknown causes; however, specific predisposing factors have not been fully addressed to date. | 23446557 |
| Infective conjunctivitis, Inflammation | Altered Intercellular Communication | Histories of infectious conjunctivitis and swimming pool exposure could be associated with the development of PANDO, although the pathogenesis of this condition has been considered as inflammation of unknown causes. | 23446557 |
| Inflammation, Chronic sinusitis, Craniosynostosis | Altered Intercellular Communication | Inflammation has been demonstrated to play a central role in the pathogenesis of chronic rhinosinusitis (CRS), and TNFa is a key pro-inflammatory cytokine with important functions in these processes. | 23446846 |
| Inflammation | Altered Intercellular Communication | Nerve pathology showed inflammation around the endoneurial microvessels and subperineurial edema and inflammation. | 23447136 |
| Inflammation, Fatty degeneration | Altered Intercellular Communication | Both serum and liver desmosterol levels correlated positively with steatosis and inflammation in the liver (P < 0.05). | 23447451 |
| Gastroenteritis, Gastrointestinal inflammation, Viral gastroenteritis | Altered Intercellular Communication | The data correlate to the severe inflammatory gastroenteritis seen in patients infected with C. jejuni/coli, whereas C. concisus-infected patients have a much lower intestinal inflammation which could be compared with viral gastroenteritis. | 23448294 |
| Inflammation, Bronchospasm | Altered Intercellular Communication | While a number of the consequences of mast cell degranulation within tissues have been documented including tissue-specific changes such as bronchospasm and the subsequent cellular infiltrate, there is little known about the immediate effects of mast cell degranulation on the associated vasculature, critical to understanding the evolution of mast cell dependent inflammation. | 23451084 |
| Inflammation, Chronic pain | Altered Intercellular Communication | The authors conducted study to analyze results of peri-articular steroid injection in the treatment of chronic pain from soft tissue inflammation after total knee arthroplasty (TKA). | 23451438 |
| Pain Distress Question, chronic, Inflammation | Altered Intercellular Communication | Local steroid injection is a safe and effective choice for treatment of pain from chronic soft tissue inflammation after TKA. | 23451438 |
| helium, Inflammation, Status Epilepticus | Altered Intercellular Communication | Occurrence of status epilepticus in HE could be related to the presence of active inflammation of cortical or para-cortical tissue, although such a hypothesis remains to be demonstrated. | 23452828 |
| Inflammation, Chronic infectious disease | Altered Intercellular Communication | IL-10-producing regulatory B cells suppress immune responses, and lack of these cells leads to exacerbated symptoms in mouse models of chronic inflammation, transplantation, and chronic infection. | 23453135 |
| Inflammation, Osteolysis, Tuberculosis, Osteoarticular | Altered Intercellular Communication | The first patient was followed up for 3 years, during which she experienced mutilating osteolysis of the fingers and very severe inflammation as assessed by osteoarticular ultrasonography. | 23453469 |
| Inflammation, Rheumatoid Arthritis, Superficial ulcer | Altered Intercellular Communication | The bone texture parameter Hmean is influenced by age, inflammation and local erosions in rheumatoid arthritis. | 23453476 |
| Inflammation | Altered Intercellular Communication | Host-induced antibodies and their contributions to cancer inflammation are largely unexplored. | 23454746 |
| Inflammation, Neoplasms, melanoma | Altered Intercellular Communication | Since Th2-biased inflammation is a hallmark of tumor microenvironments, we investigated the presence and functional implications of IgG4 in malignant melanoma. | 23454746 |
| Inflammation, Neoplasms | Altered Intercellular Communication | Consistent with Th2 inflammation, CD22+ B cells and IgG4(+)-infiltrating cells accumulated in tumors, and IL-10, IL-4, and tumor-reactive IgG4 were expressed in situ. | 23454746 |
| Inflammation, Neoplasms | Altered Intercellular Communication | These findings suggest that IgG4 promoted by tumor-induced Th2-biased inflammation may restrict effector cell functions against tumors, providing a previously unexplored aspect of tumor-induced immune escape and a basis for biomarker development and patient-specific therapeutic approaches. | 23454746 |
| Inflammation | Altered Intercellular Communication | One inflammation SNP, rs950286, was successfully replicated with a concordant odds ratio of 1.46 (1.14-1.87) in discovery, 1.37 (1.05-1.77) in replication, and a combined odds ratio of 1.40 (1.17-1.68). | 23454887 |
| Single organ dysfunction, Inflammation, cell injury | Altered Intercellular Communication | These symptoms seem to be due to extravasation of gasoline from vessels which lead to inflammation, cell damage and organ failure. | 23456531 |
| Refractory anemias, Inflammation | Altered Intercellular Communication | Despite a lack of effect on central BMD, the modest effect of anti-TNF on PIP BMD may provide evidence that BTM reflect specifically bone remodeling activity at periarticular sites of inflammation in RA and PsA. | 23457381 |
| Communicable Diseases | Altered Intercellular Communication | In addition, microRNAs affect all facets of the immune/inflammation responses to infection, which may control HPV clearance. | 23457596 |
| Inflammation, Atherosclerotic lesion | Altered Intercellular Communication | An increase in NLR has been associated with vascular endpoints reflecting inflammation in atherosclerotic lesions. | 23457609 |
| Airway structure | Altered Intercellular Communication | Many common diseases affecting the airways are characterized by airway inflammation. | 23457675 |
| Inflammation, Gastritis, Mucous Membrane, Conization, Intestinal metaplasia | Altered Intercellular Communication | The gastric biopsies of the patients were also histologically examined to ascertain the presence, nature and degree of the following histological variables of gastritis: colonisation by H. pylori; inflammation, intestinal metaplasia and mucosal atrophy. | 23457877 |
| Inflammation, Malaria | Altered Intercellular Communication | One of the main host genetic factors involved in inflammation, immune responses and pathogenesis of malaria is FcgRIIa (cd32) gene. | 23458236 |
| Inflammation, Injury of cardiac valve, Traumatic injury | Altered Intercellular Communication | The study aimed to determine if there was an early association between inflammation and secondary cardiac injury in trauma patients. | 23459112 |
| Cessation of life, Inflammation, Injury of cardiac valve | Altered Intercellular Communication | Biomarker evidence of cardiac injury and inflammation on admission is associated with a higher risk of in-hospital death. | 23459112 |
| Airway structure, Asthma | Altered Intercellular Communication | Airway inflammation is considered a central component of asthma and, therefore, international guidelines recommend antiinflammatory medications. | 23460164 |
| Inflammation, Endothelial dysfunction, Coronary heart disease, Choline Dehydrogenase, Mitochondrial | Altered Intercellular Communication | We examined the association between job strain and coronary heart disease (CHD) and investigated the role of markers of inflammation and endothelial dysfunction as possible mediators of job strain-associated CHD risk. | 23460721 |
| Inflammation, Acquired Immunodeficiency Syndrome, HIV | Altered Intercellular Communication | Monocytes and myeloid dendritic cells (mDCs) are important orchestrators of innate and human immunodeficiency virus (HIV)-specific immune responses and of the generalized inflammation that characterizes AIDS progression. | 23460749 |
| Inflammation, hepcidin | Altered Intercellular Communication | Iron status and systemic inflammation, but not gut inflammation, strongly predict gender-specific concentrations of serum hepcidin in infants in rural Kenya. | 23460869 |
| Inflammation, Anemia | Altered Intercellular Communication | Prevalence of inflammation, anemia, and iron deficiency was 31%, 71%, 26%, respectively. | 23460869 |
| Inflammation, hepcidin | Altered Intercellular Communication | We propose gender-specific reference values for serum hepcidin in iron-replete infants without inflammation. | 23460869 |
| Granulomatous inflammation, Sarcoidosis, Lesion of vulva | Altered Intercellular Communication | Biopsy results showed non-caseous granulomatous inflammation consistent with sarcoidosis in the vulvar lesion. | 23461079 |
| Orbital Pseudotumor | Altered Intercellular Communication | It's a rare disease entity which runs as a idiopathic inflammation of retina and choroid. | 23461159 |
| Neoplasms | Altered Intercellular Communication | Most tumors (3/5) exhibited predominantly endocrine differentiation without hormonal production. | 23462323 |
| Pelvic abscess, Inflammation | Altered Intercellular Communication | In vivo MR-guided freehand drainage was prospectively performed in patients with increased systemic inflammation markers and abdominal, retroperitoneal, and pelvic abscess collections. | 23462676 |
| Inflammation, Pancreatic carcinoma | Altered Intercellular Communication | Chronic inflammation may play a role in the development of pancreatic cancer. | 23462920 |
| Inflammation, Pancreatic carcinoma | Altered Intercellular Communication | In conclusion, prediagnostic levels of circulating CRP, IL-6, and TNF-aR2 were not associated with the risk of pancreatic cancer, suggesting that systemic inflammation as measured by circulating inflammatory factors is unlikely to play a major role in the development of pancreatic cancer. | 23462920 |
| Postprandial Period | Altered Intercellular Communication | No consistent significant postprandial inflammation, oxidative stress or regulation of adiponectin was observed in this study. | 23462948 |
| Inflammation, Diabetes Mellitus, Non-Insulin-Dependent | Altered Intercellular Communication | Elevated high-sensitivity C-reactive protein (hs-CRP), a marker of low-grade systemic inflammation, may be involved in the etiology of type 2 diabetes mellitus (T2DM). | 23463453 |
| Inflammation, Obesity | Altered Intercellular Communication | However, whether inflammation precedes development of T2DM independent of cigarette smoking and obesity remains to be confirmed. | 23463453 |
| Inflammation, Obesity | Altered Intercellular Communication | These findings imply that higher hs-CRP itself or existence of chronic systemic inflammation precedes onset of T2DM independent of obesity and smoking. | 23463453 |
| Inflammation, Carpal Tunnel Syndrome | Altered Intercellular Communication | Chondrocalcinosis was responsible for the systemic inflammation, the CTS, the pisotriquetral joint effusion, and the UDBM compression, which has not been reported previously. | 23463648 |
| ARCN1 gene, Inflammation, Chronic Obstructive Airway Disease | Altered Intercellular Communication | Chronic obstructive pulmonary disease (COPD) is associated with persistent inflammation and oxidative stress in susceptible individuals. | 23463699 |
| Pneumonitis | Altered Intercellular Communication | Analysis of bronchial biopsy samples showed a very strong correlation between Wnt4 and IL8 gene expression, suggesting that Wnt4 plays a role in chronic lung inflammation. | 23463699 |
| Inflammation, Neutrophil Infiltration | Altered Intercellular Communication | Wnt4, in turn, acts through the noncanonical pathway to activate epithelial cell remodeling and IL8 gene expression, leading to neutrophil infiltration and inflammation. | 23463699 |
| Inflammation, Acidosis | Altered Intercellular Communication | Cytokine secretion and markers of inflammation in relation to acidosis among chronic hemodialysis patients. | 23463880 |
| Vaginitis, Inflammation, Cervix Erosion | Altered Intercellular Communication | Gynecologic examinations revealed cervical erosion in 8 (1.6%), vaginitis in 193 (37.7%) and normal findings in 311 (60.7%); pathological evaluation reports of the smears were negative in 290 (56.6%), inflammation in 218 (42.6%) and ASC-US in 4 (0.8%), according to the 2001 Bethesda classification. | 23464481 |
| Granuloma, Inflammation | Altered Intercellular Communication | Granuloma cells in chronic inflammation express CD205 (DEC205) antigen and harbor proliferating T lymphocytes: similarity to antigen-presenting cells. | 23464965 |
| Granuloma, Granulomatous inflammation | Altered Intercellular Communication | Of these, the immune granulomas, a hallmark of granulomatous inflammation, are closely related to cell-mediated immune responses. | 23464965 |
| Inflammation | Altered Intercellular Communication | This may substantiate elevated s-TG and lowered s-HDL as markers or inducers of inflammation associated disease. | 23465506 |
| Inflammation, atherosclerotic | Altered Intercellular Communication | Our findings suggest interwoven actions of poor glycemic control, low grade inflammation and low HDL-c on atherosclerotic processes in type 2 diabetes. | 23466074 |
| vascular inflammations, Endothelial dysfunction, Atherosclerosis | Altered Intercellular Communication | Collectively, these findings demonstrate that enhanced CYP o-hydroxylase and sEH metabolic function are associated with more advanced endothelial dysfunction and vascular inflammation, respectively, in patients with established atherosclerotic cardiovascular disease. | 23466098 |
| Inflammation, Crohn Disease | Altered Intercellular Communication | Endomicroscopic analysis of major axis/minor axis ratio allows the detection of microscopic residual inflammation with greater accuracy than standard endoscopy in Crohn's disease patients in clinical remission. | 23466186 |
| Inflammation, Anemia | Altered Intercellular Communication | In addition, pre- and post-menopausal women in the lower 25-hydroxyvitamin D group were at a higher risk of iron deficient anemia and anemia of inflammation. | 23466602 |
| Inflammation, Postmenopausal state | Altered Intercellular Communication | These data suggest that adipokines and systemic inflammation may be associated with the risk of postmenopausal breast cancer independently of BMI. | 23466816 |
| Inflammation, Contracture, Microbial Biofilms | Altered Intercellular Communication | It has been hypothesized that bacterial biofilms on breast implants may cause chronic inflammation leading to capsular contracture. | 23468161 |
| Inflammation, Ischemic stroke, Haiti | Altered Intercellular Communication | Identified genes correspond to differences in inflammation and coagulation that may predispose to HT in ischemic stroke. | 23468366 |
| Inflammatory Bowel Diseases, Inflammation | Altered Intercellular Communication | In inflammatory bowel disease (IBD), genetic susceptibility together with environmental factors disturbs gut homeostasis producing chronic inflammation. | 23468882 |
| Inflammation | Altered Intercellular Communication | A meta-analysis including all available, comparable data was used to explore important aspects of IBD inflammation, thereby validating consistent gene expression patterns. | 23468882 |
| Respiratory Insufficiency, Inflammation | Altered Intercellular Communication | Respiratory impairment and systemic inflammation in cedar asthmatics removed from exposure. | 23468925 |
| Respiratory Insufficiency, Asthma, Inflammation | Altered Intercellular Communication | Years after exposure cessation, patients with Western red cedar asthma have persistent airflow obstruction and respiratory impairment, associated with systemic inflammation. | 23468925 |
| Inflammation, Albuminuria, Chronic Kidney Diseases | Altered Intercellular Communication | Although previous evidence has shown that angiopoietin-2 destabilizes vasculature and induces inflammation in different scenarios, further study will be required to delineate the role of angiopoietin-2 in albuminuria and microinflammation in CKD patients. | 23469160 |
| Inflammation, asthma chronic | Altered Intercellular Communication | Th17-related responses drive inflammation during late stages of chronic asthma and can also be blocked by ustekinumab. | 23469809 |
| Inflammatory Bowel Diseases, Inflammation, Rheumatoid Arthritis, Spondylitis | Altered Intercellular Communication | MPV is inversely correlated with inflammation in inflammatory bowel diseases, rheumatoid arthritis, and ankylosing spondylitis, as shown in the previous studies. | 23469987 |
| Degenerative polyarthritis, Inflammation, Synovitis | Altered Intercellular Communication | MPV levels may be considered as a marker of inflammation but further comprehensive prospective trials are needed in osteoarthritis associated with synovitis patients. | 23469987 |
| Inflammation, Obesity | Altered Intercellular Communication | In women, obesity is correlated with low-grade inflammation and recent data show that BMI is positively associated with thrombin generation. | 23470648 |
| Inflammation, Thrombus, Venous Thrombosis, Obesity | Altered Intercellular Communication | We explored the correlations between obesity, inflammation and thrombin generation in women with increased thrombotic risk by looking at a cohort of women with prior venous thrombosis. | 23470648 |
| Inflammation, Thrombosis, Obesity | Altered Intercellular Communication | This shows a possible link between obesity, low-grade inflammation and increased thrombin generation in women at increased risk for future thrombosis. | 23470648 |
| Inflammation, Choroidal ischemia | Altered Intercellular Communication | Fluorescence angiography and indocyanine green-angiography disclosed focal choroidal ischaemia in the area of inflammation. | 23470676 |
| Inflammation, Hereditary hemochromatosis, home health encounter, fibrogenesis | Altered Intercellular Communication | Hereditary hemochromatosis (HH) is characterized by accumulation of iron, oxidative stress, inflammation, and fibrogenesis in liver tissue. | 23471031 |
| Inflammation, Hyperparathyroidism | Altered Intercellular Communication | ESA requirements are independent of age when dose is scaled to body surface area, and ESA resistance is associated with inflammation, fluid retention, and hyperparathyroidism. | 23471197 |
| Coughing, ARCN1 gene, Airway structure | Altered Intercellular Communication | To quantify cough frequency in an unselected group of subjects with COPD and investigate the relationships between cough, reported sputum production, smoking, pulmonary function, and cellular airway inflammation. | 23471467 |
| Coughing, ARCN1 gene, Airway structure | Altered Intercellular Communication | Ambulatory objective monitoring provides novel insights into the determinants of cough in COPD, suggesting sputum production, smoking, and airway inflammation may be more important than sensitivity of the cough reflex. | 23471467 |
| Inflammation, therapeutic hemodilution, hafnium, Anemia, Renal Insufficiency | Altered Intercellular Communication | Contributors to the risk of anemia in HF include hemodilution, renal dysfunction and inflammation. | 23472188 |
| Kidney Failure, Chronic, Communicable Diseases, Inflammation, Chronic kidney disease stage 5 | Altered Intercellular Communication | Inflammation induced by infectious and noninfectious triggers in the kidney may lead to end stage renal disease (ESRD). | 23472199 |
| Inflammation, Nasal Polyps, Chronic sinusitis | Altered Intercellular Communication | Chronic rhinosinusitis with nasal polyps is characterized by B-cell inflammation and EBV-induced protein 2 expression. | 23473835 |
| Inflammation, Craniosynostosis | Altered Intercellular Communication | B cells and plasma cells are enriched in NPs, actively produce antibodies locally, and might contribute to chronic inflammation in patients with CRS. | 23473835 |
| Inflammatory abnormality of the eye | Altered Intercellular Communication | Apart from the abnormal vasculature, there were no signs of chronic ocular surface inflammation. | 23474249 |
| Inflammation, Data types - Address, CRNKL1 wt Allele, Liver Cirrhosis | Altered Intercellular Communication | We analyzed data from patients with cirrhosis and AD to establish diagnostic criteria for ACLF and showed that it is distinct from AD, based not only on the presence of organ failure(s) and high mortality rate but also on age, precipitating events, and systemic inflammation. | 23474284 |
| Inflammation, Osteolysis | Altered Intercellular Communication | Interleukin-17C was related to the inflammation of aseptic loosening, possibly by contributing to the inflammation and osteolysis in the tissues surrounding aseptic loosened implants. | 23474800 |
| Malignant tumor of colon, Adiponectin Deficiency | Altered Intercellular Communication | Mucus and adiponectin deficiency: role in chronic inflammation-induced colon cancer. | 23474825 |
| Malignant tumor of colon | Altered Intercellular Communication | This study aims to define the role of adiponectin (APN) in preventing goblet cell apoptosis and in differentiation of epithelial cells to goblet cell lineage resulting in greater mucus production and hence greater protection from chronic inflammation-induced colon cancer (CICC). | 23474825 |
| Inflammation | Altered Intercellular Communication | Chronic inflammation was induced in DSS and DSS + DMH group by administrating 2 % DSS in drinking water for 5 days followed by 5 days of normal drinking water and this constitutes one DSS cycle. | 23474825 |
| Inflammation | Altered Intercellular Communication | Three cycles of DSS were administered to induce chronic inflammation. | 23474825 |
| Refractory anemias, Inflammation | Altered Intercellular Communication | Colour Doppler activity is associated with the extent of inflammation present in the synovial biopsies from RA patients. | 23475981 |
| Inflammation | Altered Intercellular Communication | Recently, the chronic inflammation has been proposed to be involved in the pathogenesis of IR. | 23476101 |
| Inflammation, Progranulins, Diabetes Mellitus, Non-Insulin-Dependent, Obesity | Altered Intercellular Communication | These results suggested that Plasma progranulin concentrations were higher in Chinese patients with type 2 diabetes and obesity and correlated closely with glycolipid metabolism, chronic inflammation and IR. | 23476101 |
| Inflammation | Altered Intercellular Communication | Retrospective reports of weight change and inflammation in the US National Health and Nutrition Examination Survey. | 23476750 |
| Weight Gain, Inflammation, Weight decreased | Altered Intercellular Communication | The increased risk of elevated CRP among individuals who experienced at least 10 kg of weight loss or weight gain was also observed for weight change that occurred over the past 10 years; however, weight loss over the 10-year period was no longer associated with high inflammation. | 23476750 |
| Inflammation, Weight decreased | Altered Intercellular Communication | These results suggest that adult respondents who retrospectively self-reported weight loss or gain had higher levels of inflammation relative to their weight stable counterparts. | 23476750 |
| trauma to the abdomen, Neoplasms | Altered Intercellular Communication | Chyloascites is a rare complication that can result from abdominal trauma, neoplasm, inflammatory conditions, or various abdominal surgeries. | 23477184 |
| Inflammatory Bowel Diseases | Altered Intercellular Communication | IBD is a chronic inflammatory condition that is usually diagnosed in young adulthood. | 23477328 |
| Stomach Carcinoma, Gastritis | Altered Intercellular Communication | This study is designed to assess the levels of CRH in gastric tissue of a group of patients with gastric cancer and gastric chronic inflammation. | 23477585 |
| Stomach Carcinoma, Gastritis | Altered Intercellular Communication | Fifty-two patients with gastric cancer (GC) and 213 patients with gastric chronic inflammation were recruited into this study. | 23477585 |
| Hepatic inflammation | Altered Intercellular Communication | The ERLIN1-CHUK-CWF19L1 gene cluster influences liver fat deposition and hepatic inflammation in the NHLBI Family Heart Study. | 23477746 |
| Non-alcoholic Fatty Liver Disease, Hepatic inflammation, Fatty degeneration, Liver Cirrhosis | Altered Intercellular Communication | Nonalcoholic fatty liver disease (NAFLD) ranges from simple steatosis to hepatic inflammation to cirrhosis. | 23477746 |
| Non-alcoholic Fatty Liver Disease, Hepatic inflammation | Altered Intercellular Communication | We sought to identify common genetic variants contributing to NAFLD, using CT measured fatty liver (FL), and alanine aminotransferase levels (ALT), as a biochemical marker of hepatic inflammation. | 23477746 |
| Hepatic inflammation | Altered Intercellular Communication | Our findings suggest ERLIN1-CHUK-CWF19L1 variants are associated with early stage of FL accumulation (measured by CT) to hepatic inflammation (ALT levels), and the association enhances when accounting for the correlations between their scans. | 23477746 |
| Steatohepatitis, Non-alcoholic Fatty Liver Disease, Fatty degeneration, Inflammation | Altered Intercellular Communication | CMA approach enhanced the ability to identify novel variants of the ERLIN1-CHUK-CWF19L1 influencing both simple steatosis and hepatic steatosis with inflammation, which suggest that this gene cluster may regulate the susceptibility of NAFLD in a wide spectrum of disease. | 23477746 |
| Inflammation, Diabetes Mellitus, Non-Insulin-Dependent | Altered Intercellular Communication | It is associated with type 2 diabetes mellitus and adipose inflammation. | 23477808 |
| Splenomegaly, Liver Dysfunction, Pneumonitis, Hyperferritinaemia, Pancytopenia, Pleural Effusion, CTCAE, Disorder of intra-abdominal lymph nodes | Altered Intercellular Communication | Admission examinations showed severe pancytopenia, liver dysfunction, hyperferritinemia, fibrinopenia, elevated lactalase dehydrase, bilateral pulmonary inflammation and pleural effusion, abdominal lymphadenopathy, and splenomegaly. | 23478118 |
| Data types - Address | Altered Intercellular Communication | MEG delta mapping might be a serious candidate for a "neural degeneration" marker of AD reflecting dysfunctional synaptic transmission. | 23478303 |
| Inflammation, Hypertension, CTCAE, Hypertrophy | Altered Intercellular Communication | We have shown that C-344T potentially predicts higher values of LVMI and concentric hypertrophy in untreated hypertension, independently of renal function and subclinical inflammation. | 23479071 |
| Inflammation, Malignant neoplasm of gastrointestinal tract | Altered Intercellular Communication | A strong link between inflammation and gastrointestinal cancer has been demonstrated. | 23479179 |
| Communicable Diseases, Stomatitis, Radiation injury, Dermatitis, Treatment-Emergent Adverse Event, Inflammatory disease of mucous membrane | Altered Intercellular Communication | The most common grade 3/4 treatment-emergent adverse events were mucosal inflammation (73%); dermatitis (27%); and infection, radiation skin injury and stomatitis (23% each). | 23479383 |
| Inflammation, Pain Distress Question | Altered Intercellular Communication | MR imaging is sensitive for depicting tissue or fluid changes related to inflammation, a common process in causes of acute abdominopelvic pain. | 23479698 |
| Peripheral Vascular Diseases, Inflammation | Altered Intercellular Communication | An echogenic skin lesion is most likely benign and can occasionally have peripheral vascularity due to surrounding inflammation. | 23479705 |
| Myositis | Altered Intercellular Communication | [18F]FDG uptake in proximal muscles assessed by PET/CT reflects both global and local muscular inflammation and provides useful information in the management of patients with polymyositis/dermatomyositis. | 23479721 |
| Myopathy, Myositis | Altered Intercellular Communication | This study aimed to determine whether [(18)F]fluorodeoxyglucose-PET/CT ([(18)F]FDG-PET/CT) discriminates PM/DM from non-muscular diseases and also whether FDG uptake in proximal muscles reflects the activity and severity of muscular inflammation in PM/DM. | 23479721 |
| Inflammation | Altered Intercellular Communication | Our results suggest that [(18)F]FDG-PET/CT is useful in the diagnosis of PM/DM when inflammation in proximal muscles is globally assessed with quantitative measurements. | 23479721 |
| Inflammation | Altered Intercellular Communication | Our results also indicate that local FDG uptake in a proximal muscle reflects the activity of inflammation in the same muscle and provides useful information in determining the region for muscle biopsy. | 23479721 |
| Cataract, Inflammation | Altered Intercellular Communication | To evaluate anterior chamber inflammation in eyes with retained presumed intraocular cotton fibers after small-incision cataract surgery. | 23480601 |
| Cataract, Inflammation | Altered Intercellular Communication | Following cataract surgery, retained presumed intraocular cotton fibers did not cause any additional inflammation in the eye within the short term. | 23480601 |
| Cataract, Inflammation | Altered Intercellular Communication | In contrast to other intraocular foreign bodies, which may cause severe inflammation, retained intraocular cotton fibers seem to be well tolerated following cataract surgery. | 23480601 |
| Orbital Pseudotumor | Altered Intercellular Communication | IgG4 orbital inflammation in a 5-year-old child presenting as an orbital mass. | 23480695 |
| Orbital Pseudotumor | Altered Intercellular Communication | It can present as orbital inflammation or as an orbital mass. | 23480695 |
| Orbital Pseudotumor | Altered Intercellular Communication | Initially this was reported to be idiopathic orbital inflammation. | 23480695 |
| Inflammation, Granuloma, Foreign-Body | Altered Intercellular Communication | Histological reported chronic inflammation with granulomatous foreign body giant cell reaction confirming pre-operative diagnosis of tissue reaction to glue cast. | 23480817 |
| Bacteremia, Inflammation | Altered Intercellular Communication | The neutrophil-lymphocyte count ratio (NLR), a convenient marker of inflammation, has been demonstrated to be a useful biomarker for predicting bacteremia. | 23482854 |
| Inflammation, Corneal Ulcer | Altered Intercellular Communication | One week later, the inflammation subsided completely while the corneal ulcer healed and visual acuity improved dramatically. | 23483491 |
| Degenerative polyarthritis, Inflammation | Altered Intercellular Communication | Osteoarthritis (OA) is a degenerative joint disease involving a combination of cartilage degradation and inflammation. | 23483610 |
| Inflammation, Damage | Altered Intercellular Communication | This paper aims to evaluate the relationship of patient-reported tender and swollen joints with active inflammation as detected by power Doppler (PDUS) and whether this relationship is affected by significant joint damage. | 23484455 |
| Inflammation, Metabolic Syndrome X | Altered Intercellular Communication | Correlations of apelin serum levels with disease activity, systemic inflammation and metabolic syndrome were assessed. | 23484462 |
| Inflammation, Metabolic Syndrome X | Altered Intercellular Communication | No significant correlation between apelin concentration and demographic features, inflammation, adiposity and metabolic syndrome features was seen. | 23484462 |
| Inflammation, senile | Altered Intercellular Communication | (Immunity and inflammation are the defenses against invaders from the environment and responsible for repair of damaged and senile cells.) | 23484675 |
| Inflammation, MS gene | Altered Intercellular Communication | High levels of oxidative stress are associated with inflammation and play an important role in pathogenesis of multiple sclerosis. | 23485514 |
| Inflammation | Altered Intercellular Communication | In addition, HVC may lead to increased left ventricle mass index and pulmonary artery pressure and decreased ejection fraction, and low albumin levels may be attributable to inflammation. | 23485537 |
| Inflammation, Atherosclerosis | Altered Intercellular Communication | However, the mechanism underlying Th17 inflammation in atherosclerosis remains largely unknown. | 23485611 |
| Inflammation, Inflammatory disorder | Altered Intercellular Communication | Thymic stromal lymphopoietin (TSLP) is a novel IL-7-like cytokine and mainly responsible for Th2 inflammation in many inflammatory diseases. | 23485611 |
| Inflammation, Atherosclerosis | Altered Intercellular Communication | TSLP induced by ox-LDL could promote Th17 immune response in vitro, which may be implicated in Th17 inflammation in atherosclerosis. | 23485611 |
| Communicable Diseases, Milroy Disease, Inflammation, Lymphedema | Altered Intercellular Communication | A clinical diagnosis of lymphedema of unknown etiology was made; the hypotheses were that the etiology was late congenital lymphedema of the penis or lymphedema aggravated by inflammation and/or infection. | 23485846 |
| Inflammation, Heart failure | Altered Intercellular Communication | In patients with heart failure, increased apoptosis, inflammation and activation of the transforming growth factor (TGF)-b cytokine system have been documented. | 23486075 |
| Granulomatous inflammation | Altered Intercellular Communication | This is based on a single colony of mycobacterium isolated, histologic finding revealing granulomatous inflammation, and the favorable response to rifampin. | 23486124 |
| Inflammation, Hypertension, CTCAE | Altered Intercellular Communication | High ALDO levels within normal range are related to the presence of subclinical inflammation in essential hypertension. | 23486351 |
| Appendage, Inflammation, Ischemia | Altered Intercellular Communication | The aim of this case report is to present typical US and CT features of epiploic appendagitis, characterized by the ischemia and inflammation of the epiploic appendices of the colon. | 23486629 |
| Clostridium difficile infection, Gastrointestinal inflammation | Altered Intercellular Communication | Markers of intestinal inflammation, not bacterial burden, correlate with clinical outcomes in Clostridium difficile infection. | 23487367 |
| Compact Disk Interactive, Inflammation, Communicable Diseases, Clostridium difficile enteritis, Clostridium difficile colitis | Altered Intercellular Communication | To assess the contribution of ongoing infection vs persistent inflammation, we examined the correlation between fecal cytokine levels, fecal C. difficile burden, and disease outcomes in C. difficile infection (CDI). | 23487367 |
| Compact Disk Interactive, Diarrhea, Gastrointestinal inflammation | Altered Intercellular Communication | Persistent diarrhea in CDI correlates with intestinal inflammation and not fecal pathogen burden. | 23487367 |
| Inflammation, Chronic heart failure | Altered Intercellular Communication | Chronic heart failure (HF) is in part characterized by immune activation and inflammation, and factors that regulate lymphocyte trafficking and inflammation may contribute to the progression of this disorder. | 23487539 |
| Cessation of life, Inflammation, Nerve Degeneration | Altered Intercellular Communication | Oxidative stress is a widely recognized cause of cell death associated with neurodegeneration, inflammation, and aging. | 23487751 |
| vascular inflammations, Endothelial dysfunction | Altered Intercellular Communication | Besides, its cholesterol-lowering effect, the ability of simvastatin to ameliorate endothelial dysfunction through increasing NO bioavailability and through suppression of oxidative stress and vascular inflammation may play an important role in these effects. | 23488690 |
| Inflammation, Alveolar Bone Loss | Altered Intercellular Communication | Oxidative burst activity of peripheral monocytes and granulocytes is elevated in DS affected individuals and may contribute to periodontal tissue inflammation and loss of periodontal attachment in this susceptible group. | 23488730 |
| Inflammation, VITILIGO-ASSOCIATED MULTIPLE AUTOIMMUNE DISEASE SUSCEPTIBILITY 1 (finding), Pruritus | Altered Intercellular Communication | A total of 125 patients with vitiligo, who showed lesions in particular locations, onset at an older age, and/or pre-existing inflammation or pruritus, were included. | 23488983 |
| Inflammation, Impaired cognition | Altered Intercellular Communication | Population-based studies have demonstrated the association of inflammation and cognitive impairment. | 23489773 |
| Inflammation, Craniosynostosis | Altered Intercellular Communication | Higher levels of oral and nasal FeNO in ECRS patients may reflect the persistence of eosinophilic inflammation in sinus mucosa with concomitant iNOS upregulation and accompanying deposition of oxidized NO metabolites. | 23489830 |
| Inflammation, Osteoporosis | Altered Intercellular Communication | The latest data suggests that inflammation plays a critical role in bone remodeling and in pathogenesis of osteoporosis. | 23490023 |
| Inflammation, Malignant Neoplasms, Inflammatory disorder | Altered Intercellular Communication | NLR is a simple, non-invasive and cost-effective marker of inflammation in various malignancies and inflammatory diseases. | 23490023 |
| Inflammation, Osteoporosis | Altered Intercellular Communication | Elderly people with osteoporosis have elevated NLR levels, suggesting that inflammation may play an important role in bone remodeling. | 23490023 |
| Increased insulin level, Inflammation, Hyperglycemia | Altered Intercellular Communication | A "Western" lifestyle characterized by physical inactivity and excess weight is associated with a number of metabolic and hormonal dysregulations, including increased circulating estrogen levels, hyperinsulinemia, hyperglycemia, and chronic inflammation. | 23492765 |
| Increased insulin level, Inflammation, Hyperglycemia | Altered Intercellular Communication | A "Western" lifestyle characterized by physical inactivity and excess weight is associated with a number of metabolic and hormonal dysregulations, including increased circulating estrogen levels, hyperinsulinemia, hyperglycemia, and chronic inflammation. | 23492765 |
| Inflammation, Diabetes Mellitus | Altered Intercellular Communication | Diabetes is associated with persistent inflammation and defective tissue repair responses. | 23493576 |
| Inflammation, Fever, CTCAE, Lymphadenopathy | Altered Intercellular Communication | All patients presented with fever, moderate to highly elevated signs of inflammation, and local lymphadenopathy. | 23494111 |
| Inflammation, Diabetes Mellitus, Non-Insulin-Dependent | Altered Intercellular Communication | Impaired insulin sensitivity (SI) and b-cell function are the two main causes of type 2 diabetes (T2D) and are related to low-grade inflammation status. | 23494740 |
| Pain Distress Question, Inflammation, Anger | Altered Intercellular Communication | The majority of participants chose red to describe high-intensity pain; the reasons given were because red symbolized inflammation, fire, anger and the stop signal in a traffic light system. | 23495128 |
| Inflammation | Altered Intercellular Communication | Our data show that frailty and mortality rate were positively associated with chronic inflammation and with a down-regulation of multiple endocrine factors. | 23496093 |
| Inflammation, Postoperative delirium, Fluctuating consciousness, Inattention, Confusion | Altered Intercellular Communication | To determine whether intraoperative blood transfusion, a known trigger and amplifier of inflammation, is an independent risk factor for early postoperative delirium (POD), an acute state of confusion with fluctuating consciousness and inattention after surgery, in older adults undergoing surgery. | 23496244 |
| Inflammation, Helminthiasis | Altered Intercellular Communication | To evaluate systemic serum cytokine and chemokine markers for inflammation and Th1/Th2 responses in relation to multiple helminth infections, parasite burden and/or nutritional status of individuals. | 23496801 |
| pertussis vaccine | Altered Intercellular Communication | Furthermore, we measured fractional exhaled nitric oxide (FeNO) with regard to whether we could distinguish eosinophilic inflammation of the airway and pertussis. | 23496900 |
| Cerebral Amyloid Angiopathy, Inflammation | Altered Intercellular Communication | Corticosteroid therapy in a patient with cerebral amyloid angiopathy-related inflammation. | 23497126 |
| Inflammation | Altered Intercellular Communication | Computed tomography revealed bowel wall thickness and mesentery inflammation at the hepatic flexure of the colon and cecum. | 23497155 |
| Irritation - emotion, Urinary Bladder Calculi (disorder), Inflammation | Altered Intercellular Communication | Bladder calculus is associated with chronic irritation and inflammation. | 23497224 |
| Malignant neoplasm of urinary bladder, Inflammation, Carcinogenesis, Best Case Imputation Technique | Altered Intercellular Communication | As there is substantial documentation that inflammation can play a direct role in carcinogenesis, to date the relationship between stone formation and bladder cancer (BC) remains unclear. | 23497224 |
| Inflammation, Mood Disorders, Filariasis | Altered Intercellular Communication | Filariasis by inducing chronic inflammation and immunopathologic reactions seems to play a major role in infected affective disorders patients by changing levels of cytokines of the Th1 system or indirectly damaging the brain tissue. | 23497411 |
| Thrombosis, Sinusitis | Altered Intercellular Communication | Contrast enhanced CT showed dilated left superior ophthalmic vein, suggestive of thrombosis, contrast enhancement of the left cavernous sinuses, and dilation of cavernous sinus, indicating cavernous sinus inflammation. | 23497466 |
| Inflammatory abnormality of the eye | Altered Intercellular Communication | Genotypes were correlated with disease characteristics and severity of ocular inflammation. | 23497844 |
| Hyperlipidemia, Inflammation, Diabetes Mellitus, Uremia, Hypertension, CTCAE | Altered Intercellular Communication | We hypothesized that AMP patients would display a pro-inflammatory adipokine signature, and that certain clinical conditions (diabetes, hypertension, hyperlipidemia, high BMI, uremia) would independently drive elevated adipose inflammation. | 23498310 |
| Inflammation | Altered Intercellular Communication | Related to immunosenescence, a low-grade inflammation also develops with aging contributing also to increase carcinogenesis. | 23503514 |
| Pleural Diseases | Altered Intercellular Communication | Thus, dysfunction of both synaptic transmission and auditory neural function can be associated with abnormal loudness adaptation and the magnitude of the adaptation is significantly greater with ribbon synapse than neural disorders. | 23503620 |
| Inflammation, Colorectal Carcinoma | Altered Intercellular Communication | Is perioperative systemic inflammation the result of insufficient cortisol production in patients with colorectal cancer? | 23504123 |
| Communicable Diseases, Inflammation, Discitis, Osteomyelitis of vertebra | Altered Intercellular Communication | Vertebral osteomyelitis or discitis is a condition characterised by inflammation to the vertebral disc space and is often related to infection. | 23505083 |
| Inflammation, Weight decreased, Metabolic Syndrome X | Altered Intercellular Communication | Effect of the Mediterranean diet with and without weight loss on markers of inflammation in men with metabolic syndrome. | 23505168 |
| Inflammation, Weight decreased, Metabolic Syndrome X, ETV3 wt Allele | Altered Intercellular Communication | To investigate the impact of the MedDiet consumed under controlled feeding conditions before (-WL) and after weight loss (+WL) on markers of inflammation in men with metabolic syndrome (MetS). | 23505168 |
| Inflammation, Weight decreased | Altered Intercellular Communication | Thus, consuming MedDiet even in the absence of weight loss significantly reduces inflammation. | 23505168 |
| Inflammation, Weight decreased, ETV3 wt Allele | Altered Intercellular Communication | However, the degree of waist circumference reduction with weight loss magnifies the impact of the MedDiet on other markers of inflammation associated with MetS in men. | 23505168 |
| Inflammation, Fibrosis Assessment, Heart failure | Altered Intercellular Communication | Galectin-3 is a biomarker associated with inflammation and fibrosis that predicts adverse outcome and relates to biomarkers of extracellular matrix turnover in patients with heart failure, particularly when left ventricular (LV) systolic function is preserved. | 23505301 |
| Inflammation, Urinary tract infection | Altered Intercellular Communication | b-Hemolysin/cytolysin of Group B Streptococcus enhances host inflammation but is dispensable for establishment of urinary tract infection. | 23505569 |
| Inflammation, Urinary tract infection | Altered Intercellular Communication | Given the near ubiquity of bH/C-expressing strains in epidemiologic studies and the importance of local inflammation in dictating outcomes and sequelae of UTI, we hypothesize that bH/C-driven inflammatory signaling may be important in the clinical course of GBS-UTI. | 23505569 |
| Inflammation, Urinary tract infection | Altered Intercellular Communication | Given the near ubiquity of bH/C-expressing strains in epidemiologic studies and the importance of local inflammation in dictating outcomes and sequelae of UTI, we hypothesize that bH/C-driven inflammatory signaling may be important in the clinical course of GBS-UTI. | 23505569 |
| Inflammation, AHSG protein, human, Coronary Arteriosclerosis | Altered Intercellular Communication | Fetuin-A inhibits inflammation and has a protective effect against myocardial ischemia. | 23505907 |
| Inflammation, BDI - Functional Impairment, Swelling, Chronic inflammatory disorder, Arthritis | Altered Intercellular Communication | Arthritis is a chronic inflammatory disease resulting in inflammation of diarthrodial joints (particularly joints of hands, wrists, feet, knees, ankles, and shoulders), manifested by swelling and functional impairment. | 23505920 |
| Inflammation, GDC AJCC Clinical Stage Terminology | Altered Intercellular Communication | In conclusion, our observations suggest that ACS shows an increase in both remodeling and inflammation markers. | 23505923 |
| Lymphocyte count decreased, Inflammation, Critical Illness, Bacteremia | Altered Intercellular Communication | The neutrophil/lymphocyte count ratio (NLCR) has been introduced as a parameter for systemic inflammation in critically ill patients and was found, together with lymphocytopenia, to be a better predictor of bacteraemia than routine parameters like C-reactive protein and total leukocyte count. | 23506136 |
| Granuloma, Granulomatous inflammation | Altered Intercellular Communication | Histopathological examination of sea urchin granulomas shows a non-specific granulomatous inflammation, in most cases of sarcoidal type. | 23506168 |
| Inflammation, Paronychia , Keloid | Altered Intercellular Communication | Histopathological analysis of the specimen revealed the presence of irregular, thick, glassy and dense collagen of keloid and inflammation of paronychia. | 23506345 |
| Inflammation | Altered Intercellular Communication | It is implied that if an ingrown nail is not controlled, it will result in the production of chronic inflammation and tension stress, which might trigger the formation of a secondary keloid. | 23506345 |
| Inflammation, Metabolic Diseases, Atherosclerosis | Altered Intercellular Communication | As an adipocytokine, resistin has been proposed as a link between inflammation, metabolic disorder and atherosclerosis. | 23506578 |
| vascular inflammations | Altered Intercellular Communication | Oxidative stress may link multiple mechanisms of AAA including vascular inflammation and increased metalloproteinase activity. | 23506637 |
| Inflammation | Altered Intercellular Communication | Uncoupled iNOS may link oxidative stress to inflammation in AAA. | 23506637 |
| Metabolic Process, Cellular, Inflammation, Obesity, Visceral | Altered Intercellular Communication | Evidence suggests that the systemic inflammation and dysmetabolism observed in visceral obesity underpins this association. | 23507222 |
| Inflammation | Altered Intercellular Communication | There were 35 positive false zones in 20 patients (11 normal parenquima and 9 chronic inflammation). | 23507291 |
| Vascular Diseases, Inflammation | Altered Intercellular Communication | Livedoid vasculopathy is a painful, ulcerating condition of the lower legs, ankles and feet with the typical histological feature of hyalinising vascular change of dermal blood vessels with minimal inflammation. | 23508660 |
| Inflammation, Obesity | Altered Intercellular Communication | Low-grade inflammation may be involved in the changes in thyroid function and morphology in obesity. | 23509206 |
| Gingivitis | Altered Intercellular Communication | Due to irregular periodontal maintenance and poor oral hygiene, severe gingival inflammation and deep pockets persisted in the permanent dentition of the patient. | 23509838 |
| Inflammation, Depression, CTCAE | Altered Intercellular Communication | Our findings support the hypothesis that inflammation may be a mediator in the association between maternal depression and adverse perinatal outcomes. | 23509887 |
| Inflammation, Atherosclerotic lesion | Altered Intercellular Communication | Inflammation plays an essential role in the development and progression of atherosclerotic lesions. | 23511026 |
| Inflammation, Diabetes Mellitus, Non-Insulin-Dependent | Altered Intercellular Communication | Chronic inflammation plays an important role on development and progression of Type 2 diabetes (T2DM) through immunologic inflammatory mechanisms. | 23511196 |
| Inflammation, Chronic disease, Malignant Neoplasms, Cardiovascular Diseases | Altered Intercellular Communication | NLR has recently been used as a systemic inflammation marker in chronic diseases as well as a predictor of prognosis in cardiovascular diseases and malignancies. | 23511196 |
| Gastrointestinal inflammation, Burn injury | Altered Intercellular Communication | Noninvasive measurement of intestinal inflammation after burn injury. | 23511286 |
| Multiple Organ Failure, Burn Specimen Source Codes, Wounds and Injuries, Gastrointestinal inflammation | Altered Intercellular Communication | Intestinal inflammation has been linked with multiorgan failure in patients with burn and other traumatic injuries. | 23511286 |
| Gastrointestinal inflammation | Altered Intercellular Communication | We hypothesized that markers of intestinal inflammation are detectible noninvasively. | 23511286 |
| Gastrointestinal inflammation, Burn injury | Altered Intercellular Communication | Our results suggest that markers of intestinal inflammation are measurable by noninvasive means and are increased after burn injury compared with controls. | 23511286 |
| Gastrointestinal inflammation | Altered Intercellular Communication | Of note, increased IL-8 correlated with increased MPO and elastase activity, suggesting a role for neutrophil activation in burn-mediated intestinal inflammation. | 23511286 |
| Gastrointestinal inflammation, Burn injury | Altered Intercellular Communication | Thus, these inflammatory cytokine profiles may be valuable biomarkers of intestinal inflammation after burn injury. | 23511286 |
| Inflammation, Traumatic injury, Neoplasms, Congenital Rubella Syndrome | Altered Intercellular Communication | Osseous metaplasia of the eyelid is a rare entity with diverse etiologies ranging from congenital syndromes to trauma, neoplasm, and inflammation. | 23511997 |
| Inflammation | Altered Intercellular Communication | Inflammation is associated with pancreatic b-cell apoptosis and reduced insulin sensitivity. | 23514733 |
| Pain Distress Question, Inflammation, Volume Measurement | Altered Intercellular Communication | Pain, chronic relapsing inflammation and loss of volume are typical sequels of this procedure. | 23515594 |
| Inflammation, Chronic pain | Altered Intercellular Communication | At the 10-month follow-up, no inflammation was observed and chronic pain was significantly reduced. | 23515594 |
| Inflammation, Retroperitoneal fibrosis | Altered Intercellular Communication | Idiopathic retroperitoneal fibrosis (IRPF) is a rare condition of unknown aetiology characterized by chronic non-specific inflammation of the retroperitoneum. | 23515600 |
| Schistosomiasis, Infertility, Pathology | Altered Intercellular Communication | Cases of infertility in endemic areas especially when there is no supply of potable water should raise suspicion of schistosomiasis among other pathologies and possible hormonal disturbances when the testes are involved. | 23515635 |
| Inflammation | Altered Intercellular Communication | Damage-associated molecular patterns derived from mitochondria may contribute to the hemodialysis-associated inflammation. | 23515931 |
| Inflammation, Necrosis | Altered Intercellular Communication | Mitochondrial damage-associated molecular patterns (DAMPs) are released during cell necrosis or apoptosis and induce inflammation. | 23515931 |
| HD Term Type, Inflammation | Altered Intercellular Communication | The mitochondrial protein cytochrome c, as a marker of released mitochondrial DAMPs, and interleukin-6 (IL-6), as a marker of inflammation, were evaluated in HD patients. | 23515931 |
| Inflammation, Appendicitis, CTCAE | Altered Intercellular Communication | The term "neurogenic appendicopathy" has been used for patients operated on for acute appendicitis with their appendices lacking signs of acute inflammation. | 23516073 |
| Shock, Inflammation, Traumatic | Altered Intercellular Communication | Heat shock protein 90 (HSP90), a broadly distributed and conserved molecule, regulates inflammation under stressful and traumatic conditions. | 23516526 |
| Inflammation, Conjunctival scar | Altered Intercellular Communication | We have investigated host microRNA (miR) expression in health (N) and disease (conjunctival scarring with (TSI) and without (TS) inflammation) to determine if these epigenetic differences are associated with pathology. | 23516655 |
| Ulcerative Colitis, Inflammatory disease of mucous membrane | Altered Intercellular Communication | Although modifications in bowel preparation are needed, CCE-2 might be feasible for assessing the severity of mucosal inflammation in patients with UC. | 23517279 |
| Hepatitis, Chronic, FAM126A gene | Altered Intercellular Communication | The initiation and progression of HCC is closely associated with chronic liver inflammation. | 23518600 |
| Inflammation, Pathology | Altered Intercellular Communication | The regenerating islet-derived (REG) gene family encodes a group of proteins highly expressed in several human pathologies, many of which are associated with epithelial inflammation. | 23519454 |
| Inflammatory Bowel Diseases, Colitis | Altered Intercellular Communication | REGs are highly expressed during inflammatory bowel disease (IBD)-related colonic inflammation and the in vivo expression pattern of REG1A and REG4 has been localised by using immunohistochemistry. | 23519454 |
| Inflammatory Bowel Diseases, Inflammation | Altered Intercellular Communication | Samples drawn from an IBD cohort including both inflamed and un-inflamed colonic mucosa are described, as are samples from non-IBD inflammation and healthy controls. | 23519454 |
| Uveitis | Altered Intercellular Communication | Exacerbations of intraocular inflammation with transient IOP rise at the early postoperative period occurred in six patients (23 %), and were controlled with topical corticosteroid. | 23519886 |
| Inflammation, Percutaneous transhepatic cholangiography | Altered Intercellular Communication | Our results require replication but suggest that the SERPINA5 gene, which codes for the protein C inhibitor involved in many biological processes including inflammation, may be a new susceptibility locus for PTC. | 23520464 |
| Malnutrition | Altered Intercellular Communication | Nutritional counselling sessions resulted in statistically significant post-intervention improvements in Karnofsky performance scale scores, malnutrition inflammation scores and nutritional knowledge of the patients. | 23520905 |
| Airway structure, Respiration Disorders, Bronchial Hyperreactivity, Airway Obstruction | Altered Intercellular Communication | Asthma is a common respiratory disease that is characterized by bronchial hyperresponsiveness and airway obstruction due to chronic airway inflammation. | 23521807 |
| Non-alcoholic Fatty Liver Disease, Hepatic inflammation | Altered Intercellular Communication | NAFLD is associated with insulin resistance and hepatic inflammation. | 23522007 |
| Abscess | Altered Intercellular Communication | Their abscesses, located predominantly at the paracolic gutter region (P = 0.002) were associated with fistulae (P = 0.001) and caused by transmural bowel wall inflammation. | 23522395 |
| Inflammation, Hyphema, Traumatic injury | Altered Intercellular Communication | Anterior chamber inflammation and hyphema resolved 4 weeks after the trauma. | 23522587 |
| Inflammation | Altered Intercellular Communication | Subclinical injury or inflammation may play a role as possible causative factors for the development of the pigmentation. | 23522629 |
| Inflammation | Altered Intercellular Communication | Mast cell plays a role in the initiation of inflammation and therefore in poorer healing. | 23522705 |
| ARCN1 gene, Weight decreased, Muscular Atrophy, Inflammation | Altered Intercellular Communication | Weight loss and muscle wasting are common features reported in COPD patients and they are all related with systemic inflammation. | 23523152 |
| Inflammation, Dysplasia, Ulcerative Colitis | Altered Intercellular Communication | On multivariate analysis, duration of UC (Odds ratio [OR]=1.40; 95% confidence interval [CI], 1.08-1.81; P=0.01), number of random biopsies (per increase by 8) (OR=1.64; 95% CI, 1.18-2.28; P=0.003) and target biopsies during colonoscopy (OR=9.08; 95% CI, 3.18-26.0; P<0.001) independently predicted the presence of dysplasia; endoscopic features of prior inflammation did not. | 23523416 |
| Inflammation, Dysplasia, Ulcerative Colitis | Altered Intercellular Communication | Random biopsies significantly increase the yield of dysplasia in patients with PSC and UC even in the absence of endoscopic features of prior inflammation and significantly impact clinical outcomes. | 23523416 |
| helium, Inflammation, Communicable Diseases, Hepatic Encephalopathy, Liver Cirrhosis | Altered Intercellular Communication | A causal relationship between infection, systemic inflammation, and hepatic encephalopathy (HE) has been suggested in cirrhosis. | 23523580 |
| Inflammation, Ichthyosis Bullosa of Siemens, Diverticulitis, HAMA - Gastrointestinal Symptoms | Altered Intercellular Communication | Diverticulitis appears to predispose patients to long-term gastrointestinal and emotional symptoms after resolution of inflammation; in this way, postdiverticulitis IBS is similar to postinfectious IBS. | 23524129 |
| Inflammation, Steatohepatitis | Altered Intercellular Communication | Pioglitazone was more effective than glibenclamide in improving inflammation and hepatic steatosis indices. | 23524525 |
| Inflammation, Acute Cerebrovascular Accidents | Altered Intercellular Communication | Insulin resistance (IR) has effects on inflammation and oxidative stress which have importance in acute stroke. | 23524624 |
| Inflammation, Ischemic stroke, Cerebrovascular accident | Altered Intercellular Communication | Our aim was to investigate the relationships between IR, inflammation, oxidative stress and stroke severity in acute ischemic stroke patients. | 23524624 |
| Inflammation, Cerebrovascular accident, Acute Cerebrovascular Accidents | Altered Intercellular Communication | We examined the relationships between inflammation, oxidative stress and stroke severity in 75 acute stroke patients with and without IR. | 23524624 |
| Inflammation, Cerebrovascular accident | Altered Intercellular Communication | Inflammation and oxidative stress are more evident in acute stoke patients with insulin resistance which may cause worse stroke severity. | 23524624 |
| Inflammation, Coronary Arteriosclerosis | Altered Intercellular Communication | In patients recovering from coronary artery bypass (CABG), little is known about the relationship of 1) immune-mediated inflammation and resultant endothelial activation, and 2) cumulative exposure to infectious pathogens (pathogen burden (PB)) implicated in coronary atherosclerosis to exhaustion. | 23524631 |
| Communicable Diseases, Inflammation | Altered Intercellular Communication | The TCAs remained on participants' ears for an average total of 122 days, without causing signs of inflammation or infection, and there were no serious device-related adverse events. | 23524632 |
| Myositis | Altered Intercellular Communication | There were obvious ultrasonographic changes of the masseter muscle in females with MPD, which might be related to the muscle inflammation. | 23524800 |
| Inflammation | Altered Intercellular Communication | Local and chronic inflammation induced by amyloid-b (Ab) plays a central role in the development of age-related macular degeneration. | 23525277 |
| Inflammation | Altered Intercellular Communication | Our findings suggest that the degradation of TJ proteins such as zonula occludens-1, occludin and F-actin by MMP-9 secreted by Ab-stimulated cells constitutes an important mechanism in the breakdown of the barrier which contributes to chronic inflammation in the retina of age-related macular degeneration. | 23525277 |
| Inflammation, Cerebral Aneurysm | Altered Intercellular Communication | Evidence that acetylsalicylic acid attenuates inflammation in the walls of human cerebral aneurysms: preliminary results. | 23525414 |
| Inflammation, Thrombosis | Altered Intercellular Communication | VCAM and tPA may have greater specificity for processes reflecting inflammation and thrombosis in the epicardial arteries, which determine recurrent coronary events. | 23525424 |
| Inflammation | Altered Intercellular Communication | Adipose tissue inflammation and perturbation of adipokine secretion may contribute to the pathogenesis of CVD. | 23525430 |
| Inflammatory Bowel Diseases, Inflammation, Acute inflammation | Altered Intercellular Communication | PGP neutralisation in DSS-treated mice showed the importance of PGP-guided neutrophilic infiltration in the intestine and indicates a vicious circle in neutrophilic inflammation in IBD. | 23525573 |
| Inflammation, Epithelioid fibrous histiocytoma, Granuloma, Foreign-Body, Granuloma | Altered Intercellular Communication | Host histopathologic responses included nodule without foreign body reaction, nodule with chronic inflammation, granuloma with epithelioid histiocytic and multinucleated giant cell reaction. | 23526034 |
| Inflammation, Asthma | Altered Intercellular Communication | Bronchial asthma is associated with increased arterial inflammation beyond that estimated by current risk stratification tools. | 23526296 |
| Asthma | Altered Intercellular Communication | Bronchial asthma is a chronic inflammatory condition associated with increased cardiovascular (CV) events. | 23526296 |
| Sepsis, Inflammation, Coinfection | Altered Intercellular Communication | Sepsis, the syndrome of microbial infection complicated by systemic inflammation, is associated with significant morbidity and mortality. | 23526732 |
| Communicable Diseases, Inflammation, Malignant Neoplasms | Altered Intercellular Communication | PET/CT visualises infection, inflammation and malignancy, all of which may cause elevated ESR. | 23527049 |
| Inflammation, Thrombosis | Altered Intercellular Communication | Thrombospondin-1 and -2 (TSP-1 and -2) have been implicated in the regulation of angiogenesis, thrombosis, and inflammation, which are believed to be critical in the pathogenesis of cardiovascular events. | 23528028 |
| Hirschsprung Disease, Inappropriate ADH Syndrome | Altered Intercellular Communication | The patient developed Hirschsprung disease and the syndrome of inappropriate antidiuretic hormone secretion (SIADH), which had not previously been described in TUBA1A mutation-associated disease. | 23528852 |
| Graft-vs-Host Disease, Inflammatory disease of mucous membrane | Altered Intercellular Communication | S100A9-short was detected in 20 patients with GVHD, in 9 patients without GVHD, and in 8 healthy volunteers (P = .01) Further studies are needed to clarify the role of these proteins as a marker of GVHD or as an index of mucosal inflammation. | 23529013 |
| Inflammation, Fibrosis Assessment, Fatty degeneration, Fatty Liver Disease | Altered Intercellular Communication | On liver biopsy specimens, performed in each patient, the NASH score, representing the sum of fibrosis, steatosis, lobular inflammation and ballooning, was calculated. | 23529326 |
| Pulmonary Emphysema, Centriacinar Emphysema, Pneumonitis | Altered Intercellular Communication | In vivo quantification of pulmonary inflammation in relation to emphysema severity via partial volume corrected (18)F-FDG-PET using computer-assisted analysis of diagnostic chest CT. Our aim was to quantify the degree of pulmonary inflammation associated with centrilobular emphysema using fluoro-18-2-fluoro-2-deoxy-D-glucose positron emission tomography ((18)F-FDG-PET) and diagnostic unenhanced computed tomography (CT) based image segmentation and partial volume correction. | 23529388 |
| Pulmonary Emphysema, Pneumonitis | Altered Intercellular Communication | These results support the notion that pulmonary inflammation plays an important role in the pathophysiology of emphysema. | 23529388 |
| Pulmonary Emphysema, Pneumonitis | Altered Intercellular Communication | This novel image analysis approach has great potential for practical, accurate, and precise combined structural-functional PET quantification of pulmonary inflammation in patients with emphysema or other pulmonary conditions, although further validation and refinement will be required. | 23529388 |
| Inflammation | Altered Intercellular Communication | NfL levels correlated with the Expanded Disability Status Scale (EDSS) score in patients with relapsing disease (r(s) = 0.31; p = 0.002), spinal cord relapses and with CSF markers of acute inflammation. | 23529999 |
| Inflammation, Pericardial Effusion, CTCAE, Diarrhea, Early-onset, Abdominal Pain | Altered Intercellular Communication | Here, we report the case of an 11-month-old boy with early-onset, recurrent episodes of unprovoked fever lasting 7 to 10 days and associated with pericardial effusion, abdominal pain, diarrhea, and inflammation. | 23530176 |
| Renal Insufficiency, Inflammation | Altered Intercellular Communication | Similarly to RDW, impaired renal function is also associated with inflammation and protein-energy wasting. | 23530521 |
| Inflammation, Chronic Kidney Diseases | Altered Intercellular Communication | The results were consistent in subgroups of patients with different levels of haemoglobin, chronic kidney disease status and various markers of inflammation and iron status. | 23530521 |
| Inflammation, Comorbidity | Altered Intercellular Communication | Lower eGFR is associated with higher RDW, independent of comorbidity, iron deficiency, inflammation and nutritional status in kidney transplant recipients. | 23530521 |
| Inflammation, Secondary malignant neoplasm of lung, Breast Carcinoma, Obesity | Altered Intercellular Communication | Increased levels of urinary PGE-M, a biomarker of inflammation, occur in association with obesity, aging, and lung metastases in patients with breast cancer. | 23531446 |
| Inflammation, Cardiac sarcoidosis | Altered Intercellular Communication | The PET/CT scan was performed to assess disease activity of cardiac sarcoidosis, and no active cardiac inflammation was detected. | 23531736 |
| Inflammation, Diabetes Mellitus, Cardiovascular Diseases | Altered Intercellular Communication | Omentin-1 is an adipokine implicated in diabetes, inflammation, and cardiovascular disease. | 23532633 |
| Airway structure | Altered Intercellular Communication | Measurement of the fraction of exhaled nitric oxide (FeNO) is a useful test to diagnose and/or monitor eosinophilic airway inflammation. | 23532936 |
| Immunocompromised Host | Altered Intercellular Communication | Listeria monocytogenes is a rare but relevant cause of systemic inflammations in immunocompromised patients. | 23533043 |
| Inflammation, Periodontitis, Chronic Kidney Diseases | Altered Intercellular Communication | Periodontitis is an important source of systemic inflammation in CKD patients. | 23534529 |
| Aneuploidy, Neoplasms | Altered Intercellular Communication | High S-phase fraction and aneuploidy were associated with tumours with higher grade of differentiation, greater size and negative hormonal receptors. | 23534591 |
| Azoospermia | Altered Intercellular Communication | Herein, we report an interesting case of a patient who spontaneously recovered from azoospermia due to a traffic injury and present in detail the results of the hormonal examination and semen analysis. | 23534890 |
| Inflammation, ETV3 wt Allele | Altered Intercellular Communication | In this way, we can not only predict the occurrence of MetS with a relatively low-cost and routine lab test, but also can understand more about the relationships between low grade inflammation and MetS. | 23534910 |
| Inflammation, Diabetes Mellitus | Altered Intercellular Communication | In the absence of an interrelationship between vascular function and thermoregulation, the contribution of inflammation to BTV was increased in subjects with diabetes (BTV, 0.59+-0.21degC for C-reactive protein [CRP] <0.08 mg/dl vs. 0.79+-0.28degC for CRP >0.08 mg/dl, P=0.014). | 23535220 |
| Endocrine System Diseases, Traumatic injury | Altered Intercellular Communication | Hormonal disturbances, trauma, immunosuppression, actinic damages and radiotherapy have been suggested as possible etiologic factors; however, the exact pathophysiology remains unclear. | 23535945 |
| Arterial Stiffness, Inflammation, Coronary Artery Disease | Altered Intercellular Communication | Inflammation does not influence arterial stiffness and pulse-wave velocity in patients with coronary artery disease. | 23535991 |
| Inflammation | Altered Intercellular Communication | Developing evidence suggests that inflammation may be another risk factor. | 23535991 |
| Inflammation, Liver carcinoma, Adenocarcinoma of pancreas | Altered Intercellular Communication | It has been shown that MPV level is a sign of inflammation in hepatocellular carcinoma and pancreatic adenocarcinoma. | 23537073 |
| Inflammation, Diabetes Mellitus, Coronary heart disease, Choline Dehydrogenase, Mitochondrial | Altered Intercellular Communication | Magnesium influences endothelial function, inflammation, blood pressure, and diabetes, but a direct relation with coronary heart disease (CHD) risk has not been established. | 23537810 |
| Sepsis, Inflammation | Altered Intercellular Communication | A 9-month-old infant presented with fatal pneumococcal sepsis and attenuated inflammation indices. | 23538514 |
| Inflammation, Cystic Fibrosis | Altered Intercellular Communication | Cigarette smoke and smoking-induced inflammation decrease cystic fibrosis transmembrane conductance regulator (CFTR) activity and mucociliary transport in the nasal airway and cultured bronchial epithelial cells. | 23538783 |
| Inflammation | Altered Intercellular Communication | The NLRs indicative of the balance between host immunity and cancer-related inflammation were consistently lower in the PFS-long group than in the PFS-short group, suggesting that lower NLR is associated with better clinical response. | 23539200 |
| Inflammation, CEREBRAL AMYLOID ANGIOPATHY, ITM2B-RELATED, 1, HIV Infections | Altered Intercellular Communication | No differences in CRF2 expression profile were observed in distal/sigmoid intestinal biopsies from HIV infection and FBD patients, showing no signs of inflammation. | 23539366 |
| Inflammation, Ulcerative Colitis | Altered Intercellular Communication | The down-regulation of the CRF2 receptor in the distal/sigmoid biopsies of UC patients is indicative of change in CRF2 signalling associated with the process of inflammation. | 23539366 |
| Inflammation, Colonic Diverticulitis, Diverticulitis | Altered Intercellular Communication | Detection of endoscopic and histological inflammation after an attack of colonic diverticulitis is associated with higher diverticulitis recurrence. | 23539385 |
| Inflammation, Diverticulitis | Altered Intercellular Communication | The aim of our study was to investigate the role of endoscopic and histological inflammation as predictors for the recurrence of diverticulitis. | 23539385 |
| Inflammation | Altered Intercellular Communication | At the end of the follow-up period, endoscopic inflammation was still detected in 31 (27.67%) patients, and active histological inflammation in 41 patients (36.6 %). | 23539385 |
| Inflammation, Diverticulitis | Altered Intercellular Communication | Only detection of endoscopic and of histological inflammation during the follow-up was a predictor of diverticulitis recurrence (Log rank test, p = 0.0004). | 23539385 |
| Inflammation, Diverticulitis | Altered Intercellular Communication | Detection of endoscopic and histological inflammation after attack of AUD was identified as a predictor of diverticulitis recurrence. | 23539385 |
| Inflammation | Altered Intercellular Communication | Inhibition of release of inflammatory mediators by p38 inhibitors may be a useful treatment for chronic inflammation of the airways thought to underlie the pathogenesis of the disease. | 23539534 |
| Inflammation, Pain, Postoperative, Microorganism | Altered Intercellular Communication | Acute periapical inflammation is the most common cause of postoperative pain developing as a result of mechanical, chemical and/or microbial injury of periapical tissue. | 23539905 |
| Inflammation, Hemorrhage, Carotid Stenosis | Altered Intercellular Communication | Both magnetic resonance detected carotid plaque hemorrhage (MRI PH(+)) and features of inflammation are associated with increased risk of cerebrovascular events in patients with carotid stenosis. | 23540670 |
| Inflammation, Dental Plaque | Altered Intercellular Communication | To further assess the potential of MRI PH as a biomarker for complicated carotid plaque, its relationship with inflammation needs to be assessed. | 23540670 |
| Vasculitis, Non-Small Cell Lung Carcinoma | Altered Intercellular Communication | The densities of tumor-associated CD66b(+) neutrophils and CD163(+) macrophages in NSCLC were correlated with adverse prognostic factors and systemic blood inflammation markers, but not directly correlated with RFS or OS. | 23540719 |
| Inflammation, Non-Small Cell Lung Carcinoma | Altered Intercellular Communication | Further research of chronic inflammation in NSCLC is warranted. | 23540719 |
| Inflammation, hepcidin | Altered Intercellular Communication | Inflammation plays an important role in the regulation of hepcidin expression. | 23540794 |
| Inflammation, Metaplasia, Urothelial Hyperplasia | Altered Intercellular Communication | Nonneoplastic processes were found in 70 of 108 patients (65%), including inflammation, metaplasia, and urothelial hyperplasia, with or without atypia/dysplasia. | 23540860 |
| Inflammation, Dysplasia, Metaplasia, Diverticulum | Altered Intercellular Communication | Inflammation, metaplasia, and dysplasia are commonly seen in vesical diverticula. | 23540860 |
| Inflammation, Exanthema, Communicable Diseases, Leukopenia, Thrombocytopenia | Altered Intercellular Communication | Mucosal inflammation, thrombocytopenia, neutropenia, infection, and skin rash were more frequent when everolimus was added to paclitaxel. | 23541564 |
| Hyperparathyroidism, Primary, Osteopenia | Altered Intercellular Communication | In primary hyperparathyroidism (PHPT), protracted elevation of serum parathyroid hormone (PTH) is held to be associated with cortical, but not trabecular, bone loss. | 23541782 |
| Inflammation, Gastrointestinal mucositis | Altered Intercellular Communication | Data comparing basal cells from buccal vs. gingival mucosa identified differential gene expression of host responses in relation to pathways relevant to oral mucositis pathogenesis, including responses to cancer-associated inflammation. | 23541936 |
| Inflammation | Altered Intercellular Communication | OxPL circulate in plasma, are transported by Lp(a), and deposit in the vascular wall and induce local inflammation. | 23541965 |
| Inflammation, Fibrosis Assessment, Renal cyst, Chronic Kidney Diseases, Enlarged kidney | Altered Intercellular Communication | The treatment with tolcapone markedly attenuated the loss of renal function, inhibited renal enlargement, shifted the size distribution of renal cysts and retarded cell proliferation, apoptosis, inflammation and fibrosis development in affected (cy/+) male and female PKD/Mhm and PKD/US rats. | 23543593 |
| Autoimmune Diseases, Inflammation, Frontotemporal dementia | Altered Intercellular Communication | Given the association between systemic inflammation and other neurodegenerative processes, links between autoimmunity and FTD need to be explored. | 23543794 |
| Inflammation, Disease, GRN wt Allele | Altered Intercellular Communication | These findings suggest a unique pattern of systemic inflammation in svPPA and PGRN and open new research avenues for understanding and treating disorders associated with underlying transactive response DNA-binding protein 43 aggregation. | 23543794 |
| Aneuploidy, Inflammation, Dysplasia | Altered Intercellular Communication | Neither a correlation between aneuploidy and inflammation (p = 0.916) nor between aneuploidy and dysplastic lesions (p = 0.159) could be observed. | 23544594 |
| Aneuploidy, Inflammation, Dysplasia | Altered Intercellular Communication | Furthermore, aneuploidy seems to be irrespective of inflammation or dysplasia. | 23544594 |
| Aneurysm, carotid disease, Carotid Artery Diseases, Intracranial Aneurysm | Altered Intercellular Communication | Although it is hypothesized that inflammatory signals and/or hemodynamic stress resulting from carotid disease increase the risk of aneurysm formation and growth, a relationship between intracranial aneurysms and extracranial carotid artery disease (ECAD) has not been explored. | 23545151 |
| Inflammation | Altered Intercellular Communication | Phospholipid transfer protein (PLTP) modulates lipoprotein metabolism and plays an important role in inflammation and oxidative stress. | 23545183 |
| Inflammation | Altered Intercellular Communication | Inflammation has also been linked with development of cardiovascular events (CVE) in T2DM. | 23546612 |
| Aggressive course, Inflammation | Altered Intercellular Communication | Intratumoral inflammation is associated with more aggressive prostate cancer. | 23546767 |
| Inflammation, Prostate carcinoma, Malignant Neoplasms | Altered Intercellular Communication | Inflammation may play a role in the development and progression of many cancers, including prostate cancer. | 23546767 |
| Aggressive course, Inflammation, Prostate carcinoma | Altered Intercellular Communication | We sought to test whether histological inflammation within prostate cancer was associated with more aggressive disease. | 23546767 |
| Inflammation, Neoplasms | Altered Intercellular Communication | The area with the greatest tumor burden was scored in a blinded manner for the degree of inflammation: absent, mild, or marked. | 23546767 |
| Inflammation | Altered Intercellular Communication | No inflammation was found in 49 men (17%), while 153 (53%) and 85 (30%) had mild and marked inflammation. | 23546767 |
| Inflammation | Altered Intercellular Communication | On multivariate analysis, more inflammation was associated with greater risk of positive margins, capsular penetration, and seminal vesicle invasion (all p < 0.05). | 23546767 |
| Inflammation | Altered Intercellular Communication | Marked inflammation was associated with increased PSA recurrence risk when adjusting for preoperative features only (HR 2.08, 95% CI 1.02-4.24), but not after adjusting for pathologic features. | 23546767 |
| Aggressive course, Inflammation, Prostate carcinoma | Altered Intercellular Communication | Inflammation within prostate cancer was associated with more advanced disease, although it is unclear whether aggressive disease caused increased inflammation or inflammation caused aggressive disease. | 23546767 |
| ARCN1 gene, Inflammation, Abnormal renal function | Altered Intercellular Communication | We tested the hypothesis that COPD patients, even in those with mild-to-moderate airflow obstruction, are affected by systemic inflammation associated with abnormal renal functional reserve. | 23547633 |
| Renal Insufficiency, ARCN1 gene, Airway Obstruction, Inflammation | Altered Intercellular Communication | A greater impairment in renal functional reserve of COPD patients was correlated with more severe airway obstruction and inflammation. | 23547633 |
| Inflammation, Myocarditis, CTCAE 5.0 | Altered Intercellular Communication | In 3/5 with CMR positive for myocarditis, coronary arteries were normal, but endomyocardial biopsy revealed inflammation with normal PCR. | 23547732 |
| Anemia | Altered Intercellular Communication | The high prevalence of H. pylori exposure, together with dietary iron adequacy, suggests an inflammation-driven iron deficiency and mild anemia. | 23547888 |
| Inflammation, Asthma | Altered Intercellular Communication | Eosinophilic inflammation of the small airways is a key process in asthma that often smolders in treated patients. | 23548532 |
| Colitis, Short Bowel Syndrome | Altered Intercellular Communication | Gut microbial diversity is reduced and is associated with colonic inflammation in a piglet model of short bowel syndrome. | 23549027 |
| antimony, Inflammatory disease of mucous membrane, Short Bowel Syndrome, Malabsorption Syndrome, Bacterial resistance, Intestines, Small | Altered Intercellular Communication | Following small bowel resection (SBR), the luminal environment is altered, which contributes to clinical manifestations of short bowel syndrome (SBS) including malabsorption, mucosal inflammation and bacterial overgrowth. | 23549027 |
| Inflammation | Altered Intercellular Communication | This decrease in diversity was associated with an increase in colonic inflammation six weeks post-surgery. | 23549027 |
| Inflammatory disease of mucous membrane | Altered Intercellular Communication | SBR significantly decreased the diversity of the colonic microbiota and this was associated with an increase in colonic mucosal inflammation. | 23549027 |
| Inflammation, Anti-Neutrophil Cytoplasmic Antibody-Associated Vasculitis, Necrotizing vasculitis | Altered Intercellular Communication | Anti-neutrophil cytoplasmic antibody-associated (ANCA-associated) small vessel necrotizing vasculitis is caused by immune-mediated inflammation of the vessel wall and is diagnosed in some cases by the presence of myeloperoxidase-specific antibodies (MPO-ANCA). | 23549081 |
| Inflammation, Postoperative Complications, Glaucoma, CTCAE | Altered Intercellular Communication | Outcome measures include visual acuity, intraocular pressure, need for glaucoma surgery, postoperative complications, and control of inflammation. | 23549097 |
| airway disease, Bronchial Hyperreactivity, Airway structure | Altered Intercellular Communication | Asthma is a chronic airway disease characterized by airway inflammation, bronchial hyperresponsiveness and airflow obstruction. | 23550166 |
| Lipodystrophy, Inflammation | Altered Intercellular Communication | Lipodystrophy and inflammation predict later grip strength in HIV-infected men: the MACS Body Composition substudy. | 23550976 |
| Inflammation | Altered Intercellular Communication | Body fat changes in HIV-infected persons are associated with increased systemic inflammation and increased mortality. | 23550976 |
| Lipodystrophy, Inflammation | Altered Intercellular Communication | Inflammation, lower LBM, and lipodystrophy in HIV-infected men were associated with lower subsequent grip strength. | 23550976 |
| Inflammation | Altered Intercellular Communication | These findings suggest that inflammation may contribute to declines in functional performance, independent of age. | 23550976 |
| Limbic Encephalitis, Encephalitis, Inflammation, Autoimmune Diseases | Altered Intercellular Communication | Autoimmune epilepsy was suspected clinically when there was any of the following: (1) recognizable syndromes such as NMDAR encephalitis or limbic encephalitis, (2) evidence of CNS inflammation in cerebrospinal fluid or on magnetic resonance imaging (MRI), (3) the presence of other autoimmune diseases, or (4) positive response to immunotherapy. | 23551014 |
| Vasomotor instability, Neurogenic Inflammation, Allergic | Altered Intercellular Communication | Possible mechanisms include odor induced, emotional change, vasomotor instability, trigeminal-induced neurogenic inflammation, and allergic response. | 23551212 |
| Inflammation, Pruritus | Altered Intercellular Communication | The high prevalence of pruritus in elderly patients is attributed in part to the decline in the normal physiology of the advanced aging skin, and reflects poor hydration, impaired skin barrier, and altered neural function, all ultimately contributing to inflammation and pruritus. | 23551366 |
| vascular inflammations | Altered Intercellular Communication | Lipoprotein-associated phospholipase A2 (Lp-PLA2) is an independent risk factor for CVD and has been proposed as a marker of vascular inflammation. | 23551952 |
| Granulomatous inflammation, Scleritis, Necrosis | Altered Intercellular Communication | The areas of scleritis showed complete disruption of sclera collagen, necrosis and infiltration with neutrophils, macrophages, lymphocytes, and granulomatous inflammation with MNGC. | 23552359 |
| Granulomatous inflammation, Scleritis | Altered Intercellular Communication | Granulomatous inflammation in ASK is probably responsible for the continuance and progression of the scleritis and management protocols should include immunosuppressive agents alongside amoebicidal drugs. | 23552359 |
| Follicle, Alopecia, CTCAE, Perifolliculitis | Altered Intercellular Communication | Biopsies revealed perifollicular lymphocytic inflammation and evidence of follicular injury but normal hair density, consistent with a nonscarring alopecia. | 23552567 |
| Inflammation, Alopecia, CTCAE | Altered Intercellular Communication | Nilotinib therapy may induce perifollicular inflammation and widespread persistent alopecia. | 23552567 |
| Inflammation, Fibrosis Assessment, Actinomyces israelii (bacteria), Squamous metaplasia | Altered Intercellular Communication | Histopathologic examination demonstrated chronic inflammation in 11 eyes (36.7%), fibrosis in 7 eyes (23.3%), chronic inflammation and fibrosis in 4 eyes (13.3%), squamous metaplasia in 3 eyes (10%), normal conjunctival mucosa in 3 eyes (10%), and Actinomyces israelii canaliculitis in 2 eyes (6.7%). | 23552606 |
| Inflammation, Fibrosis Assessment | Altered Intercellular Communication | Nearly all histopathologic specimens revealed findings consistent with inflammation, fibrosis, or both. | 23552606 |
| Inflammation, Stenosis of lacrimal punctum | Altered Intercellular Communication | These findings provide evidence to support the hypothesis that the many etiologic causes of punctal stenosis are linked by a common pathophysiologic mechanism involving inflammation. | 23552606 |
| allergic inflammation | Altered Intercellular Communication | An allergic inflammation was suspected to have occurred in the spermatic cord. | 23552761 |
| Inflammation, Neoplasms | Altered Intercellular Communication | A 51-year-old woman presented with a non-specific tumor of the iris and intraocular inflammation of the left eye. | 23552857 |
| Inflammation, Primary malignant neoplasm, Diabetes Mellitus, Cardiovascular Diseases | Altered Intercellular Communication | A high intake of trans fatty acids decreases HDL cholesterol and is associated with increased LDL cholesterol, inflammation, diabetes, cancer, and mortality from cardiovascular disease. | 23553155 |
| Inflammation, Myositis, CTCAE 5.0 | Altered Intercellular Communication | Some PBC cases are complicated by myositis, which is difficult to confirm due to minimal histological evidence of inflammation in limb muscles. | 23553600 |
| Inflammation, Vascular Diseases, Atherosclerosis | Altered Intercellular Communication | Elevated rho-kinase activity as a marker indicating atherosclerosis and inflammation burden in polyvascular disease patients with concomitant coronary and peripheral arterial disease. | 23553913 |
| Inflammation, Primary malignant neoplasm | Altered Intercellular Communication | The highest values of IL-6 were obtained in early cancer (more than 8-fold increase), which seems to confirm the presence of acute inflammation. | 23554823 |
| Inflammation | Altered Intercellular Communication | Residual inflammation at ICU discharge may have impact upon long-term mortality. | 23555017 |
| Communicable Diseases, Inflammation, septic | Altered Intercellular Communication | Since infection is a potent trigger of inflammation, we hypothesized that CRP levels at discharge would correlate with long-term mortality in septic patients and that the CRP/albumin ratio would be a better marker of prognosis than CRP alone. | 23555017 |
| Inflammation, Neoplasms | Altered Intercellular Communication | These findings implicate CAFs as an important target for blocking inflammation in the tumor microenvironment and reducing tumor growth. | 23555186 |
| Arthralgia, Inflammation, Chikungunya Fever | Altered Intercellular Communication | This study demonstrates that chronic arthralgia is a frequent complication of acute Chikungunya disease and suggests that it results from a local rather than systemic inflammation. | 23556021 |
| Hemorrhage, Hyponatremia | Altered Intercellular Communication | We describe herein the case of a 68-year-old female presenting with a bleeding rectal mass involving the anal canal, which case was associated with hyponatremia due to inappropriate serum levels of antidiuretic hormone. | 23556266 |
| Inflammation, Liver Cirrhosis, FAM126A gene | Altered Intercellular Communication | Inflammation in background cirrhosis evokes malignant progression in HCC development from HCV-associated liver cirrhosis. | 23556482 |
| Inflammation, Malignant Neoplasms | Altered Intercellular Communication | It is accepted that inflammation promotes malignant progression in the development of cancers. | 23556482 |
| Inflammation, Necrosis | Altered Intercellular Communication | To evaluate the inflammation, piece meal necrosis, intra lobular cellular degeneration and focal necrosis, portal cellular inflammation (0-4, each) were estimated. | 23556482 |
| Inflammation, Cirrhotic, FAM126A gene | Altered Intercellular Communication | Inflammation in the background non-cancerous cirrhotic portion would evoke malignant progression in HCC development from HCV-associated LC. | 23556482 |
| methyldopa, Inflammation | Altered Intercellular Communication | Chronic inflammation is implicated in the pathogenesis of AMD. | 23557734 |
| Inflammation | Altered Intercellular Communication | The source of chronic inflammation is often attributed to the progressive activation of immune cells over time. | 23557734 |
| Inflammation | Altered Intercellular Communication | However, recent studies have shown that senescent cells can alter tissue microenvironment via secretion of growth factors, proteases, and inflammatory cytokines and might be an additional source of chronic inflammation. | 23557734 |
| methyldopa, Inflammation | Altered Intercellular Communication | We hypothesized that altered secretory pattern in Ab-induced senescent RPE cells may contribute to compromised RPE barrier integrity and chronic inflammation in AMD. | 23557734 |
| methyldopa, Inflammation | Altered Intercellular Communication | The altered secretory phenotype of senescent RPE cells may contribute to age-related inflammation in AMD. | 23557734 |
| Mood Disorders | Altered Intercellular Communication | Alterations in mu-opioid neurotransmission may underlie limbic system activity and mood disorders in IR-PCOS. | 23557757 |
| Inflammation, Meningoencephalitis, Meningitis | Altered Intercellular Communication | Of 117 cases in the database with a diagnosis of meningitis or meningoencephalitis, 39 had neutrophilic inflammation in the meninges. | 23558577 |
| Arthritis | Altered Intercellular Communication | Relaxin hormone may play a role in the development of arthritis at the thumb CMC joint. | 23559157 |
| Communicable Diseases, Inflammation | Altered Intercellular Communication | No evidence of infection or inflammation was detected. | 23559361 |
| BDI - Functional Impairment, Inflammation | Altered Intercellular Communication | Association of functional impairment with inflammation and immune activation in HIV type 1-infected adults receiving effective antiretroviral therapy. | 23559466 |
| BDI - Functional Impairment, Inflammation, HIV-1 | Altered Intercellular Communication | The relationships of inflammation, immune activation, and immunosenescence markers with functional impairment in aging human immunodeficiency virus type 1 (HIV-1)-infected persons are unknown. | 23559466 |
| Inflammation, Thrombosis | Altered Intercellular Communication | The exact underlying mechanisms responsible for AVF failure are unknown but processes like proliferation, inflammation, vascular remodeling, and thrombosis are thought to be involved. | 23559680 |
| Inflammation, Mediastinal Emphysema | Altered Intercellular Communication | Initial chest computed tomography (CT) showed pneumomediastinum and local inflammation, but follow-up CT showed improved pneumomediastinum. | 23560657 |
| Inflammation, Malnutrition | Altered Intercellular Communication | In conclusion, these results suggest that the earthquake increased the incidence of HF in association with high blood pressure, interruption of drugs, inflammation, malnutrition, and fluid retention. | 23561586 |
| Vitreous inflammatory cells | Altered Intercellular Communication | Seven patients had anterior chamber and eight had vitreous inflammation. | 23561607 |
| Inflammation, Depressed mood | Altered Intercellular Communication | Despite immune suppression, PMNL transmigration was increased and p38 phosphorylation capacity was not depressed, which may contribute to end organ inflammation and dysfunction. | 23561969 |
| Inflammation, GDC Disease Response Terminology, Diabetes Mellitus | Altered Intercellular Communication | These genes are still of particular interest because they are involved in insulin regulation, inflammation, lipid signaling and apoptosis pathways, all of which are possibly involved with DR. Our finding nominates possible novel loci as potential DR susceptibility genes in the Chinese that are independent of the level of HbA1c and duration of diabetes and may provide insight into the pathophysiology of DR. | 23562823 |
| vascular inflammations, Atherosclerosis | Altered Intercellular Communication | Simvastatin suppresses vascular inflammation and atherosclerosis in ApoE(-/-) mice by downregulating the HMGB1-RAGE axis. | 23564080 |
| vascular inflammations, Atherosclerosis | Altered Intercellular Communication | High mobility group box protein 1 (HMGB1) and receptor for the advanced glycation end product (RAGE) play pivotal roles in vascular inflammation and atherosclerosis. | 23564080 |
| vascular inflammations, Atherosclerosis | Altered Intercellular Communication | The aim of this study was to determine whether the HMGB1-RAGE axis was involved in the actions of simvastatin on vascular inflammation and atherosclerosis in ApoE(-/-) mice. | 23564080 |
| Atherosclerosis | Altered Intercellular Communication | Vehicle-treated ApoE(-/-) mice exhibited significant increases in aortic inflammation and atherosclerosis as well as enhanced expression of HMGB1, RAGE, VCAM-1, and MCP-1 in aortic tissues as compared to the wild-type mice. | 23564080 |
| vascular inflammations, Atherosclerotic lesion | Altered Intercellular Communication | Administration with simvastatin in ApoE(-/-) mice markedly attenuated the vascular inflammation and atherosclerotic lesion area, and decreased the aortic expression of HMGB1, RAGE, VCAM-1, and MCP-1. | 23564080 |
| vascular inflammations, Atherosclerosis | Altered Intercellular Communication | Simvastatin inhibits vascular inflammation and atherosclerosis in ApoE(-/-) mice, which may be mediated through downregulation of the HMGB1-RAGE axis. | 23564080 |
| Inflammation, Fibrosis Assessment | Altered Intercellular Communication | Interleukin (IL)-17A, the signature cytokine of Th17 cells, was recently described to promote inflammation and fibrosis within the liver. | 23564624 |
| Inflammation, Fibrosis Assessment | Altered Intercellular Communication | These data should prompt further studies investigating the link between pathogen responses, inflammation, and fibrosis in patients with PSC. | 23564624 |
| Prostate, Neoplasms | Altered Intercellular Communication | Conditional transgenic expression of PIM1 kinase in prostate induces inflammation-dependent neoplasia. | 23565217 |
| Lesion, Inflammation | Altered Intercellular Communication | Analysis of senescence induced in these prostatic lesions showed that the lesions induced in the presence of inflammation exhibited different behavior than those induced in the absence of inflammation. | 23565217 |
| Inflammation, vinyltriethoxysilane | Altered Intercellular Communication | Statins reduce levels of inflammation biomarkers; however, the mechanism for the reduction in VTE risk is unknown. | 23565981 |
| Fibrous, Obstruction, Inflammation | Altered Intercellular Communication | There were various sites of obstruction and various conditions such as oedematous thickening of the mucosa of the lacrimal duct and fibrous tissue because of chronic inflammation. | 23566023 |
| Inflammation, Gilbert Disease (disorder) | Altered Intercellular Communication | Protection from age-related increase in lipid biomarkers and inflammation contributes to cardiovascular protection in Gilbert's syndrome. | 23566065 |
| Sepsis, Inflammation, Traumatic, Cerebrovascular accident | Altered Intercellular Communication | Patients treated in one of the Intensive Care Units (ICU) at the University Hospital Bonn diagnosed with sepsis or systemic inflammatory response syndrome (n = 12) and patients who were treated due to traumatic brain injury, or stroke without clinical or laboratory signs of sepsis or major inflammation (n = 22) were included. | 23566119 |
| Left Ventricular Function | Altered Intercellular Communication | The influence of atorvastatin on parameters of inflammation left ventricular function, hospitalizations and mortality in patients with dilated cardiomyopathy--5-year follow-up. | 23566246 |
| Acute Kidney Injury, CTCAE, Inflammation, Anemia | Altered Intercellular Communication | Serum Soluble-Fas, Inflammation, and Anemia in Acute Kidney Injury. | 23566289 |
| Inflammation, Kidney Failure, Acute | Altered Intercellular Communication | In multivariate analysis, after adjusting for markers of inflammation and iron stores, only serum sFas levels (P = 0.03) correlated negatively with Hb concentration in the AKI group. | 23566289 |
| Inflammation, "Alzheimers Disease", Data types - Address | Altered Intercellular Communication | Immune activation and inflammation represent critical factors in the pathogenesis of Alzheimer's disease (AD) and are associated with increased blood concentrations of markers like neopterin and the kynurenine to tryptophan ratio (Kyn/Trp). | 23566485 |
| Behavioral and psychological symptoms of dementia | Altered Intercellular Communication | In chronic inflammatory conditions, also increased serum phenylalanine concentrations and phenylalanine to tyrosine ratios (Phe/Tyr) were reported and could relate to neuropsychiatric symptoms. | 23566485 |
| Inflammation, Neoplasms | Altered Intercellular Communication | These results suggest that EGFR-TKIs may suppress systemic inflammation and promote tumor shrinkage. | 23566546 |
| Inflammation, Hypertension, CTCAE, Obesity | Altered Intercellular Communication | Vitamin D (VD) may be implicated in obesity and its complications such as insulin resistance, hypertension, and low-grade inflammation. | 23566943 |
| Inflammation, Chronic Obstructive Airway Disease, Hypertension, CTCAE | Altered Intercellular Communication | [Biomarkers of systemic inflammation, oxidative stress and their interactions in patients with combined flow of chronic obstructive pulmonary disease and arterial hypertension]. | 23567304 |
| Inflammation | Altered Intercellular Communication | Significant correlations between biomarkers of systemic inflammation and oxidative stress were found. | 23567304 |
| Inflammation, Aortic Valve Stenosis, Hypertrophic Cardiomyopathy | Altered Intercellular Communication | Myocardial hypertrophy is associated with inflammation and activation of endocannabinoid system in patients with aortic valve stenosis. | 23567807 |
| Inflammation, Fibrosis Assessment, Traumatic injury | Altered Intercellular Communication | Endocannabinoids and their receptors have been associated with cardiac adaptation to injury, inflammation and fibrosis. | 23567807 |
| Inflammation | Altered Intercellular Communication | Taken together, these results suggest a prominent role for MCPIP1 in the control of inflammation and immune homeostasis. | 23567898 |
| Acute inflammation, Inflammatory disease of mucous membrane, Infection caused by Helicobacter pylori | Altered Intercellular Communication | Histopathological examination of the lesion revealed chronic mucosal inflammation with acute inflammation and H. pylori infection. | 23569348 |
| Acute inflammation, Inflammatory disease of mucous membrane, Infection caused by Helicobacter pylori | Altered Intercellular Communication | Histopathological examination revealed chronic mucosal inflammation with acute inflammation and a very small amount of H. pylori infection. | 23569348 |
| Inflammation | Altered Intercellular Communication | H. pylori-associated severe inflammation can lead to neoplastic changes in histiocytes. | 23569348 |
| Steatohepatitis, Fibrosis Assessment, Fatty degeneration, Inflammation | Altered Intercellular Communication | The severity of hepatic steatosis increased in patients with hepatic steatosis, compared to those without steatosis (P < 0.01), but the severities of inflammation and fibrosis in the non-hepatic steatosis group were dramatically higher than those in the hepatic steatosis group (P < 0.01). | 23569427 |
| Inflammation, Vasculitis, CTCAE | Altered Intercellular Communication | Anti-neutrophil cytoplasmic antibody (ANCA) associated vasculitis, comprise a group of diseases characterized by inflammation of the wall of small vessels. | 23570759 |
| Inflammation, Nasopharyngeal carcinoma | Altered Intercellular Communication | Chronic inflammation plays an important role in nasopharyngeal carcinoma (NPC) development and progression. | 23571148 |
| Degenerative polyarthritis, Inflammation, Knee joint | Altered Intercellular Communication | Standardized CDUS examinations were performed in 111 knee joints of 106 patients (70 women and 36 men) presenting with severe OA (n = 72) or confirmed IA (n = 39) of one or both knee joints to determine the degree of synovial inflammation in a semiquantitative fashion. | 23571653 |
| Inflammation, Atrial Fibrillation by ECG Finding | Altered Intercellular Communication | To improve the clinical utility of MPV and role of inflammation in the pathogenesis of atrial fibrillation, further studies are needed to be carried out. | 23571683 |
| Inflammation, Thrombosis | Altered Intercellular Communication | For example, they become procoagulant when undergoing apoptosis and may contribute to thrombosis or inflammation. | 23571768 |
| Inflammation, Psoriasis | Altered Intercellular Communication | Chemokines may contribute to the systemic inflammation that is linked to the increased risk of co-morbidities in patients with psoriasis. | 23571825 |
| Inflammation, Psoriasis | Altered Intercellular Communication | The sustained high expression of inflammatory chemokines is a potential link to systemic inflammation in psoriasis. | 23571825 |
| HD Term Type, Inflammation, Cardiovascular system | Altered Intercellular Communication | Chronic inflammation, as measured by higher serum IL-6 levels, in combination with high basal NO is associated with worse clinical outcomes in terms of all-cause and cardiovascular death in clinically stable prevalent HD patients. | 23572414 |
| Impaired cognition | Altered Intercellular Communication | This finding seems to suggest in humans the observation made in animal models that not only b-amyloid protein, but also tau and phospho-tau proteins, are involved in the aberrant regulation of neural transmission possibly contributing to EEG deterioration, cognitive decline and worse prognosis. | 23574167 |
| Inflammation, PEELING SKIN SYNDROME | Altered Intercellular Communication | Taken together, our findings suggest that these lower levels of SSA-specific memory B cells in PB and absence of SSA-specific memory B cells in SG of pSS patients could result from activation of these cells into plasma cells at the site of inflammation. | 23574319 |
| Inflammation, Obesity | Altered Intercellular Communication | Obstructed subjects exhibited greater evidence of systemic inflammation, abnormal glucose homeostasis, and central obesity than controls. | 23574362 |
| Inflammation, Asthma | Altered Intercellular Communication | Individuals with coexisting asthma and fixed airflow obstruction have heightened systemic inflammation. | 23574362 |
| Inflammation, Complex Regional Pain Syndromes, Pain Distress Question | Altered Intercellular Communication | Exaggerated inflammation and oxidative stress are involved in the pathogenesis of Complex Regional Pain Syndrome (CRPS). | 23574939 |
| Retinal Detachment, Inflammation | Altered Intercellular Communication | Chronic recurrent presentation was significantly associated with more severe anterior segment inflammation at presentation as indicated by presence of mutton-fat keratic precipitates, anterior chamber reaction >=2+, iris nodules and posterior synechiae (p < 0.001 for all comparisons), less exudative retinal detachment at presentation (p < 0.001), more complications during the follow-up period (p < 0.001) and a worse visual outcome (p < 0.001). | 23575246 |
| Retinal Detachment, Inflammation, Complication Aspects | Altered Intercellular Communication | Chronic recurrent VKH disease is significantly associated with more severe anterior segment inflammation and less exudative retinal detachment at presentation, more ocular complications and a worse visual outcome than initial-onset acute VKH disease. | 23575246 |
| Pleurisy, Pleural effusion disorder | Altered Intercellular Communication | CA-125 levels in benign pleural effusions may not be influenced by pleural inflammation or hydrostatic or oncotic pressure changes. | 23575338 |
| Inflammation, Tissue Adhesions | Altered Intercellular Communication | After conversion of the first case to laparoscopy because of severe inflammation and adhesions, the following 14 consecutive transgastric procedures were completed. | 23575528 |
| Hyperglycemia, Electrocardiogram: myocardial infarction (finding), Inflammation | Altered Intercellular Communication | Acute hyperglycaemia and inflammation in patients with ST segment elevation myocardial infarction. | 23575781 |
| Hyperglycemia, Inflammation, GDC AJCC Clinical Stage Terminology | Altered Intercellular Communication | Acute hyperglycaemia in patients with ACS may be associated with increased systemic inflammation. | 23575781 |
| Inflammation, GDC AJCC Clinical Stage Terminology | Altered Intercellular Communication | Leukocytes are the major cellular mediators of inflammation and their elevated count is associated with higher CV event rate in ACS patients. | 23575781 |
| Intestinal Diseases, Inflammatory disease of mucous membrane | Altered Intercellular Communication | Patients with enteropathy or intestinal mucosal inflammation (associated with dysmotility or short bowel) were significantly shorter than patients without enteropathy (P = 0.007). | 23576042 |
| Intestinal Diseases, Inflammatory disease of mucous membrane | Altered Intercellular Communication | Children with enteropathy or intestinal mucosal inflammation are at greatest risk of growth failure. | 23576042 |
| Fibrosis Assessment, Myocarditis | Altered Intercellular Communication | Recently, galectin-3 emerged as a marker of myocardial inflammation and fibrosis which may influence LV remodelling after surgery. | 23576289 |
| Toxoplasma, Vitreous inflammatory cells | Altered Intercellular Communication | The absence of vitreous inflammation: one more challenge in diagnosing toxoplasma papillitis. | 23576658 |
| Inflammation, Precocious atherosclerosis, Lupus Erythematosus, Systemic | Altered Intercellular Communication | The reasons for the premature atherosclerosis in SLE are incompletely understood, although chronic inflammation is thought to play an important role. | 23577189 |
| Inflammation, Lupus Erythematosus, Atherosclerosis | Altered Intercellular Communication | This data suggests that the effects of MMF on the immune system may not only be beneficial for lupus, but also for inflammation driving lupus-associated atherosclerosis. | 23577189 |
| Inflammation, Calcinosis | Altered Intercellular Communication | An inverse correlation was found between the extension of calcification and cap inflammation (r(2) = 0.017; p = 0.003). | 23578355 |
| Inflammation, "Alzheimers Disease", Data types - Address | Altered Intercellular Communication | Dendritic cells (DCs), the main actors of immune responses and inflammation, may play a role in Alzheimer's disease (AD). | 23578995 |
| Inflammatory abnormality of the eye | Altered Intercellular Communication | Mycobacterial ocular inflammation: delay in diagnosis and other factors impacting morbidity. | 23579549 |
| Mycobacterium Infections, Inflammatory abnormality of the eye, Tuberculosis | Altered Intercellular Communication | Tuberculosis and atypical mycobacterial infection should be in the differential diagnosis of ocular inflammation, regardless of patient ethnicity. | 23579549 |
| Inflammation, Calcinosis, Cerebrovascular accident | Altered Intercellular Communication | Five days after the stroke, a F-fluoride PET/CT to evaluate calcification and, 24 hours later, a F-FDG PET/CT to evaluate inflammation were carried out. | 23579977 |
| Tears body substance, Inflammation | Altered Intercellular Communication | Overall the protein modulation shown in POAG tears proves the involvement of biochemical networks linked to inflammation. | 23580065 |
| methyldopa, Inflammation, Choroidal Neovascularization | Altered Intercellular Communication | Inflammation and immune cells regulate choroidal neovascularization (CNV) and could become therapeutic targets in age-related macular degeneration (AMD). | 23580489 |
| Refractory anemias, Rheumatoid Arthritis, Inflammation, Necrosis | Altered Intercellular Communication | Anti-tumour necrosis factor-alpha (TNF-a) inhibitors provide fast, effective resolution of rheumatoid arthritis (RA) inflammation. | 23581251 |
| Inflammation, Intraocular inflammation | Altered Intercellular Communication | He was initially treated with intravitreal bevacizumab and had visual acuity improvement and resolution of the subretinal fluid on OCT. After 8 injections, he developed presumed mild inflammation secondary to intravitreal bevacizumab and was switched to combination intravitreal bevacizumab/dexamethasone in his left eye, which consistently demonstrated efficacy in stabilizing his vision and the CNVM without producing intraocular inflammation. | 23581613 |
| Sleep-Disordered Breathing, Inflammation, Chronic Kidney Diseases, Congestive heart failure | Altered Intercellular Communication | ASV improves the prognosis of CHF patients with CKD and SDB, with favorable effects such as the improvement of cardiorenal function and attenuation of inflammation and sympathetic nervous activity. | 23582088 |
| Uremia, Inflammation, physiopathological | Altered Intercellular Communication | Protein carbamylation, a posttranslational modification promoted during uremia and catalyzed by myeloperoxidase (MPO) at sites of inflammation, is linked to altered protein structure, vascular dysfunction, and poor prognosis. | 23582087 |
| Corneal Endothelial Cell Loss, Inflammatory abnormality of the eye, Cataract, PEX19 gene, Pseudoexfoliation | Altered Intercellular Communication | To compare corneal endothelial cell damage and ocular inflammation after cataract surgery in eyes with and without pseudoexfoliation (PXF). | 23582364 |
| Asthma | Altered Intercellular Communication | Switching from salmeterol/fluticasone to formoterol/budesonide combinations improves peripheral airway/alveolar inflammation in asthma. | 23583566 |
| Asthma, SFC (Brand Name) | Altered Intercellular Communication | To assess whether switching from SFC to FBC improves peripheral airway/alveolar inflammation in asthma (UMIN000009619). | 23583566 |
| Asthma, Complete Blood Count, SFC (Brand Name) | Altered Intercellular Communication | Switching therapy from SFC to FBC improves asthma control and peripheral airway/alveolar inflammation even though there is no improvement in pulmonary functions, and FeNO in asthmatic patients. | 23583566 |
| Wounds and Injuries | Altered Intercellular Communication | Recent experimental studies have suggested that chemokines, a subclass of chemoattractant cytokines which play an important role in regulating leukocyte migration and intercellular communication, participate in brain responses of traumatic injury. | 23584220 |
| Pain Distress Question, Cysticercosis, Inflammation, Blepharoptosis | Altered Intercellular Communication | Here, we present a case of ocular cysticercosis which presented with mild pain, ptosis, inflammation of upper eyelid and slightly restricted ocular motility. | 23584662 |
| Pain Distress Question, Inflammation, Blepharoptosis | Altered Intercellular Communication | A twelve-year-old girl presented with mild pain, unilateral ptosis and inflammation of the right upper eyelid for seven months. | 23584662 |
| Intraocular inflammation, Granule, Cytomegalovirus Retinitis, Necrosis of retina, Immune System Diseases | Altered Intercellular Communication | In patients with limited immune dysfunction, a mixed clinical picture of intraocular inflammation with panretinal occlusive vasculopathy, more characteristic of acute retinal necrosis, and peripheral slowly progressive granular retinitis, more characteristic of classic CMV retinitis, is observed. | 23584702 |
| Inflammation, Endocrine Glands | Altered Intercellular Communication | Pericardial adipose tissue (PAT), a visceral fat depot surrounding the heart, serves as an endocrine active organ and is associated with inflammation. | 23584714 |
| Atrial Fibrillation, Inflammation, Atrial Fibrillation by ECG Finding | Altered Intercellular Communication | There is growing evidence that atrial fibrillation (AF) is linked with inflammation, which in turn can be a promoter of left atrial remodeling. | 23584714 |
| Inflammation, Malnutrition, Cardiovascular Diseases | Altered Intercellular Communication | Malnutrition and inflammation are the most important causes of cardiovascular disease in hemodialysis patients. | 23585319 |
| Left ventricular systolic dysfunction, Myocarditis | Altered Intercellular Communication | On multivariate analyses there was no significant relationship between SBP and (1) wall-motion score index (as an index of left-ventricular systolic dysfunction) or (2) T2 enhancement on cardiac magnetic resonance imaging and peak N-terminal pro-brain natriuretic peptide (as indices of myocardial inflammation). | 23585361 |
| Hypotension, CTCAE, Orchitis, Systolic dysfunction | Altered Intercellular Communication | Importantly, initial hypotension does not imply severe left ventricular inflammation or systolic dysfunction. | 23585361 |
| Data types - Address | Altered Intercellular Communication | In individuals with AD, very limited evidence currently exists to support the hypothesis that AChEIs may influence inflammatory blood markers and function beyond the enhancement of neuronal transmission. | 23585364 |
| Inflammation | Altered Intercellular Communication | Such scores were also able to track changes in DAS28-CRP and were significantly associated with both joint inflammation measured by ultrasound and damage progression measured by radiography. | 23585841 |
| Atrial Fibrillation, Inflammation, Comorbidity, Atrial Fibrillation by ECG Finding | Altered Intercellular Communication | Atrial fibrillation (AF) is associated with inflammation and a prothrombotic state; however, it is still unclear whether this is independent of ageing and comorbidity. | 23586783 |
| Inflammation, Acanthosis, Keratosis | Altered Intercellular Communication | The 23 biopsy samples of ARK were selected and pathological features were revised (keratosis, acanthosis, surface architecture, and inflammation). | 23587097 |
| Inflammation, Ototoxicity, Brain Injuries | Altered Intercellular Communication | HI brain damage was also associated with increases in excitotoxicity (increased glutamate/N-acetylaspartate ratio), oxidative stress (decreased glutathione/creatine ratio and increased protein carbonylation) and inflammation (increased brain IL-1 levels). | 23587650 |
| Inflammation, Cutaneous Small Vessel Vasculitis | Altered Intercellular Communication | A renal biopsy showed small-vessel vasculitis with normal glomeruli and inflammation in the interstitium. | 23588339 |
| Inflammation, Fibromyalgia, Federated States of Micronesia, Autonomic nervous system disorders, Endothelial dysfunction | Altered Intercellular Communication | Recent evidence suggests that patients with fibromyalgia (FM) have increased oxidative stress, inflammation, endothelial dysfunction and autonomic dysfunction. | 23588409 |
| Unconscious State, Wounds and Injuries, Traumatic injury, pituitary dysfunction | Altered Intercellular Communication | Hormonal imbalances may also be observed after mild but repeated trauma without loss of consciousness and should be considered in cases of isolated pituitary dysfunction, since such traumas may often occur in contacts sports such as boxing or intensive soccer play. | 23589045 |
| Inflammation, Neoplasm Metastasis, Structure of posterior cerebral artery | Altered Intercellular Communication | In conclusion, MF stromal cells from PCa participate in the progression and metastasis of PCa, modualting inflammation, angiogenesis and epithelial cancer cell proliferation. | 23589051 |
| Dehydration, Diarrhea, Inflammatory disease of mucous membrane, Colitis | Altered Intercellular Communication | In Arm2 (n = 33), LBY135 (1-40 mg/kg) plus capecitabine resulted in 3 DLTs (each grade 3): dehydration and mucosal inflammation (1 mg/kg), colitis (20 mg/kg), and diarrhea (40 mg/kg). | 23589214 |
| Osteomyelitis, Coxitis, Malignant Neoplasms | Altered Intercellular Communication | Arthrocentesis and needle biopsy of the femoral neck were not diagnostic for malignancy and revealed only mild hip joint inflammation, leading to a diagnosis of osteomyelitis. | 23589809 |
| Eosinophilic inflammation | Altered Intercellular Communication | Cluster 1 (n = 69) consisted of patients with severe eosinophilic inflammation-predominant asthma and persistent airflow limitation despite high-intensity anti-inflammatory treatment, with relatively low symptom scores. | 23590217 |
| Inflammation, Infection | Altered Intercellular Communication | Body temperature, inflammation, and infections may modify response to thrombolytic therapy. | 23590464 |
| Inflammation, Congestive heart failure | Altered Intercellular Communication | The robust association between NT-pro BNP, a diagnostic and prognostic marker in CHF, and sRAGE concentrations might suggest a possible BNP pathway of amplification of inflammation via the AGE/RAGE system. | 23590548 |
| Poor fine motor coordination, Parkinson Disease, palladium, Involuntary Movements, Bradykinesia | Altered Intercellular Communication | Parkinson's disease (PD) results from the depletion of dopamine and other neurotransmitters within the basal ganglia, and is typically characterized by motor impairment (e.g., bradykinesia) and difficulty initiating voluntary movements. | 23591046 |
| Inflammation, Colorectal Carcinoma | Altered Intercellular Communication | Chronic inflammation may mediate risk of colorectal cancer (CRC); however, the association between circulating inflammatory markers and risk of CRC has been inconsistent. | 23591192 |
| Inflammation, Myocardial Ischemia, Atherosclerosis | Altered Intercellular Communication | Chronic low-grade inflammation is involved in the initiation and progression of atherosclerosis and ischemic heart disease. | 23591413 |
| Inflammation | Altered Intercellular Communication | A diet based on marine mammals from the Arctic does not reduce inflammatory activity and it may be speculated that markers of inflammation reflect the disease rather than the cause of the disease. | 23591413 |
| Inflammation, Stomach Carcinoma, Gastritis | Altered Intercellular Communication | Moreover, AID expression is highest in the antrum and correlated with severity of chronic inflammation and IM, suggesting an important role for AID in gastric cancer development through gastritis. | 23591766 |
| Inflammation, Gastric Intestinal-Type Adenocarcinoma | Altered Intercellular Communication | Local inflammation is a strong risk factor for the development of gastrointestinal adenocarcinomas. | 23591979 |
| Inflammation, Myocardial Infarction | Altered Intercellular Communication | The elevation of markers of inflammation and of myocardial necrosis after percutaneous coronary intervention may interfere with clinical outcome. | 23592528 |
| Inflammation, Chronic Kidney Diseases | Altered Intercellular Communication | -374 T/A RAGE polymorphism could be associated with CKD progression and inflammation. | 23593165 |
| Inflammation | Altered Intercellular Communication | However, the HGF biologic activity at local inflammation sites was reduced, and this effect was associated with the amount of periodontal bacteria. | 23594192 |
| Atherogenesis, Inflammation, Atherosclerosis | Altered Intercellular Communication | Inflammation has an important place in the formation of atherogenesis and atherosclerosis. | 23594688 |
| Inflammation, Arthritis, Membranoproliferative Glomerulonephritis, Type II | Altered Intercellular Communication | This established the diagnosis of CPP crystal deposition disease, while the inflammation of the pubic symphysis was considered as acute crystal deposition arthritis related to calcium pyrophosphate dihydrate crystal deposition. | 23595192 |
| Inflammation, Ulcerative Colitis | Altered Intercellular Communication | Ulcerative colitis (UC) is associated with differential expression of genes involved in inflammation and tissue remodeling. | 23595390 |
| Diabetes Mellitus, Non-Insulin-Dependent | Altered Intercellular Communication | Micro-inflammation characterized by disturbed Treg/Teff balance with increasing sIL-2R in patients with type 2 diabetes. | 23595796 |
| Inflammation | Altered Intercellular Communication | To explore the significance of peripheral CD4(+) regulatory T cells and CD4(+) effector T cells in T2DM, we analyzed inflammation, humoral and cellular immune state in patients with T2DM. | 23595796 |
| immunoglobulin A | Altered Intercellular Communication | (1) micro-inflammation state in T2DM: Serum CRP, C3, IgA and plasma sIL-2 R were all significantly higher in T2DM than those in healthy control (HC) (all P<0.05). | 23595796 |
| Inflammation | Altered Intercellular Communication | Micro-inflammation state in T2DM was characterized by increased sIL-2 R, elevated CD3(+)CD4(+)T cells and the imbalance of Treg cells and Teff cells, which as one of the pathogeneses took part in inflammation reaction in T2DM. | 23595796 |
| Waldenstrom Macroglobulinemia, Pancreatic Intraductal Papillary Mucinous Neoplasm, Fibrosis Assessment, Neoplasms | Altered Intercellular Communication | Using the same criteria, we proceeded to a clinical review of 12 extra cases of IPMN in which the tumour or the surrounding pancreas showed significant lymphoplasmacytic inflammation and/or fibrosis. | 23596150 |
| Proteinuria, Inflammation, Glomerulonephritis | Altered Intercellular Communication | [The research on xiaochalhu decoction improving the inflammation of chronic glomerulonephritis patients and relieving the proteinuria]. | 23596780 |
| Proteinuria, Inflammation, Cancer Genetics Network, Immune System Diseases | Altered Intercellular Communication | XD could improve the inflammation by regulating the immune disorder of CGN patients with Shaoyang disease, which proved that the theory of mediating Shaoyang meridian could be used to improve the inflammation of CGN patients, thus relieving the proteinuria. | 23596780 |
| Inflammation | Altered Intercellular Communication | NF-kB is a major regulator of inflammation that controls the expression of many genes involved in atherogenesis. | 23597852 |
| Inflammation, Atherosclerosis | Altered Intercellular Communication | Our study demonstrates that targeting NF-kB nuclear translocation hampers inflammation and atherosclerosis development and identifies cell-permeable NLS peptide as a potential anti-atherosclerotic agent. | 23597852 |
| ARCN1 gene, Inflammation | Altered Intercellular Communication | Assessments of lung function, allergen testing and sputum analysis for inflammation, bacteria and fungus were undertaken in COPD subjects and healthy smoking and nonsmoking controls. | 23598955 |
| Inflammation, Sleep Apnea Syndromes | Altered Intercellular Communication | Sleep apnoea, sleepiness, inflammation and insulin resistance in middle-aged males and females. | 23598957 |
| Inflammation, Sleep Apnea, Obstructive, Osage language | Altered Intercellular Communication | In obese males obstructive sleep apnoea (OSA) is associated with inflammation and insulin resistance; however, findings are confounded by adipose tissue, a hormone- and cytokine-secreting organ. | 23598957 |
| Inflammation, Osage language | Altered Intercellular Communication | In conclusion, OSA is associated with sleepiness, inflammation and insulin resistance, even in nonobese males, and this association is stronger in males than in females. | 23598957 |
| Inflammation, Sleep Apnea, Obstructive, Osage language | Altered Intercellular Communication | In obese males obstructive sleep apnoea (OSA) is associated with inflammation and insulin resistance; however, findings are confounded by adipose tissue, a hormone- and cytokine-secreting organ. | 23598957 |
| Inflammation, Primary malignant neoplasm | Altered Intercellular Communication | Increased hematopoietic cell turnover, chronic inflammation, and reduced immune function have led to speculation that cancer risk may be higher in this group. | 23599029 |
| Damage, Acute inflammation | Altered Intercellular Communication | Iris damage, postoperative inflammation, and use of long-term corticosteroids were significantly greater in group I (p<0.001, p<0.001, p=0.005 respectively). | 23599193 |
| Inflammation, Traumatic injury, Musculoskeletal Pain, osteitis pubis, Spondylarthropathies | Altered Intercellular Communication | Osteitis pubis is a non-infective inflammation of the symphysis pubis, which is known to be associated with trauma, athletic exertion, urological or gynecological surgery, or with rheumatic conditions such as seronegative spondyloarthropathies. | 23599946 |
| Airway structure, Asthma | Altered Intercellular Communication | Respiratory mechanics and peripheral airway inflammation and dysfunction in asthma. | 23600542 |
| Airway structure | Altered Intercellular Communication | The correlation between respiratory impedance and spirometry has been reported; however, the association with airway inflammation and pulmonary function, in the lung periphery in particular, is unclear. | 23600542 |
| Asthma, physiopathological | Altered Intercellular Communication | To assess whether respiratory impedance is associated with peripheral airway inflammation and dysfunction in asthma. | 23600542 |
| Airway structure, Asthma | Altered Intercellular Communication | We sought to determine if the ALOX5 promoter SP1 tandem repeat polymorphism was associated with changes in cysteinyl leukotriene production, lung function, airway inflammation and asthma control score. | 23600541 |
| Inflammation, Primary malignant neoplasm, fibrogenesis | Altered Intercellular Communication | Compared with quiescent HSCs, peritumoral HSCs and intratumoral CAMFs expressed considerable up- and down-regulated genes associated with biological process, cellular component, molecular function and signaling pathways involved in fibrogenesis, inflammation and progress of cancer. | 23601182 |
| Inflammatory abnormality of the eye | Altered Intercellular Communication | The success rate in reducing corticosteroid to prednisone <= 10 mg/d within 6 months, while maintaining control of ocular inflammation, was 89.7% (95% confidence interval [CI], 81.1-93.5%). | 23601800 |
| Inflammation, Neoplasms | Altered Intercellular Communication | Clinical manifestations of XP include mild to extreme sensitivity to ultraviolet radiation resulting in inflammation and neoplasia in sun-exposed areas of the skin, mucous membranes, and ocular surfaces. | 23601806 |
| Inflammation, Neoplasms, Eye Abnormalities, Ocular surface disease, Abnormal cornea morphology | Altered Intercellular Communication | Structural eyelid abnormalities, neoplasms of the ocular surface and eyelids, tear film and tear production abnormalities, ocular surface disease and inflammation, and corneal abnormalities were present in this population. | 23601806 |
| methyldopa, Inflammation | Altered Intercellular Communication | Recently, complement activation and chronic inflammation have been implicated in the pathogenesis of AMD. | 23601964 |
| methyldopa, Inflammation, Disease | Altered Intercellular Communication | While AGEs have been shown to promote inflammation in other diseases, whether it plays a similar role in AMD is not known. | 23601964 |
| Inflammation | Altered Intercellular Communication | The main categories were inflammation (interferon-induced, immune response) and proteasome degradation, followed by caspase signaling. | 23601964 |
| methyldopa, Inflammation | Altered Intercellular Communication | The pathways and novel genes identified here highlight inflammation as a key response to AGE stimulation in primary culture of human RPE, and identify chemokine CXCL11 as putative novel agent associated with the pathogenesis of AMD. | 23601964 |
| Vascular anomaly, Inflammation, Fibrosis Assessment, Deformity | Altered Intercellular Communication | Intralesional injection of pingyangmycin for the treatment of orbital vascular malformations is an effective method that involves mild inflammation, fibrosis, and reduced vascularity of the malformation. | 23603483 |
| Communicable Diseases, Inflammation, Lymphoma, Malignant Neoplasms | Altered Intercellular Communication | Other differential diagnosis usually includes malignancy such as lymphoma or metastatic disease, infection, or sterile inflammation. | 23603590 |
| Neoplastic, Inflammation, Head and neck structure | Altered Intercellular Communication | To make clinicopathological correlation of head and neck lesions and to assess the frequency of incidences of different sites, age groups, sex, and distribution among inflammation and neoplastic lesion. | 23603620 |
| allergic inflammation | Altered Intercellular Communication | Although the high-affinity LTB4 receptor BLT1 has been shown to exert proinflammatory roles, the role of BLT2 in allergic inflammation has not been clarified. | 23603839 |
| Asthma | Altered Intercellular Communication | These findings indicate that BLT2 has a protective role in allergic airway inflammation and that diminished BLT2 expression in CD4(+) T cells may contribute to the pathophysiology of asthma. | 23603839 |
| Inflammation, Atherosclerosis | Altered Intercellular Communication | Low-grade inflammation plays an independent and important role in atherosclerosis. | 23604041 |
| Inflammation, Acute myocardial infarction | Altered Intercellular Communication | Association between chronic periodontal and apical inflammation and acute myocardial infarction. | 23604464 |
| Inflammation, Fibrosis Assessment, Blood-Retinal Barrier | Altered Intercellular Communication | Loss of blood-retinal barrier (BRB) integrity associated with vitreoretinal fibrin deposition, inflammation, fibrosis and neovascularization contribute to the pathophysiological processes in these disorders. | 23604512 |
| Vitreoretinal Area | Altered Intercellular Communication | Retinal pigment epithelial (RPE) cells are well recognized to contribute to vitreoretinal inflammation/fibrosis and are likely to encounter contact with coagulation factor upon loss of BRB integrity. | 23604512 |
| PDR gene, Retinitis, Fibrosis Assessment, methyldopa, Disorder of vitreous body | Altered Intercellular Communication | Our findings suggest that factor Xa and thrombin can drive vitreoretinal inflammation and fibrosis and should be considered as treatment targets in vitreoretinal disorders such as PVR, PDR and AMD. | 23604512 |
| Encrusted cystitis, Cystitis, Bacterial Infections | Altered Intercellular Communication | Encrusted cystitis is characterized by chronic inflammation of the bladder with encrustation of the mucosa, induced by urea-splitting bacterial infection. | 23605319 |
| Inflammation, Gastrointestinal mucositis | Altered Intercellular Communication | Radiotherapy in the head and neck region and chemotherapy might give rise to oral mucositis which is a severe and painful inflammation. | 23605599 |
| allergic inflammation | Altered Intercellular Communication | How long-lived Eos, despite the continued presence of GM-CSF or IL-5, eventually undergo apoptosis to end allergic inflammation remains unclear. | 23606538 |
| ARCN1 gene, Inflammation | Altered Intercellular Communication | Influence of age, past smoking, and disease severity on TLR2, neutrophilic inflammation, and MMP-9 levels in COPD. | 23606791 |
| ARCN1 gene, Inflammation | Altered Intercellular Communication | Efforts to understand the mechanisms of TLR2 signalling and subsequent MMP-9 production in COPD may assist in understanding neutrophilic inflammation in COPD. | 23606791 |
| Degenerative polyarthritis, Inflammation | Altered Intercellular Communication | There is increasing evidence that inflammation in the synovium plays a major role in the progression of osteoarthritis (OA). | 23607395 |
| Inflammation, Thrombosis | Altered Intercellular Communication | Mannan-binding lectin-associated serine proteases (MASPs) MASP-1 and MASP-2 of the complement lectin pathway contribute to clot formation and may represent an important link between inflammation and thrombosis. | 23607747 |
| Fibrosis Assessment, prostatitis | Altered Intercellular Communication | Periurethral fibrosis secondary to prostatic inflammation causing lower urinary tract symptoms: a prospective cohort study. | 23608423 |
| Fibrosis Assessment, Lower Urinary Tract Symptoms, prostatitis | Altered Intercellular Communication | To investigate the role periurethral fibrosis secondary to chronic prostatic inflammation as a potential contributing factor to the etiology of lower urinary tract symptoms (LUTS) in male patients. | 23608423 |
| Inflammation, Leucocytic infiltrate | Altered Intercellular Communication | Of the 30 patients, 21 (70%) presented with inflammatory infiltration and 9 (30%) had no inflammation. | 23608423 |
| Inflammation | Altered Intercellular Communication | The histologic evaluation showed a higher collagen quantity (P = .04) and lower, albeit not statistically significant, elastin amount (P = .19) in the inflammation group. | 23608423 |
| Lower Urinary Tract Symptoms, prostatitis | Altered Intercellular Communication | Prostate inflammation may induce fibrotic changes in periurethral prostatic tissues, and this may eventually promote urethral stiffness and LUTS. | 23608423 |
| palladium, Inflammation, deficiency aspects | Altered Intercellular Communication | It has recently been proposed that inflammation, suggesting as a causal factor for PD, is enhanced by Parkin deficiency. | 23608757 |
| Cessation of life, Inflammation | Altered Intercellular Communication | Here, we provide the evidence that Parkin suppresses inflammation and cytokine-induced cell death by promoting the proteasomal degradation of TRAF2/6 (TNF-a receptor-associated factor 2/6). | 23608757 |
| palladium, Inflammation | Altered Intercellular Communication | Our results strongly suggest that the reduction of Parkin or overexpression of TRAF2/6 by chronic inflammation would be the reason for occurrence of PD. | 23608757 |
| Polymyositis, Myositis, CTCAE 5.0, Abnormal degeneration, Myositis | Altered Intercellular Communication | Sporadic inclusion body myositis (sIBM) and polymyositis (PM) are characterized by muscle inflammation, with sIBM showing additional degenerative alterations. | 23608825 |
| Inflammation, Inflammatory disorder | Altered Intercellular Communication | S100A12 is overexpressed during inflammation and is a marker of inflammatory disease. | 23611140 |
| Inflammation | Altered Intercellular Communication | Furthermore, it has been ascribed to the group of damage-associated molecular pattern molecules that promote inflammation. | 23611140 |
| Sepsis, Inflammation | Altered Intercellular Communication | Human S100A12 is an endogenous TLR4 ligand that induces monocyte activation, thereby acting as an amplifier of innate immunity during early inflammation and the development of sepsis. | 23611140 |
| Inflammation | Altered Intercellular Communication | The frequency of iceA2 and its subtype iceA2_D were higher (p<0.015) in cases with moderate/severe granulocytic inflammation. | 23611633 |
| Gingivitis, Systemic Scleroderma | Altered Intercellular Communication | Factors associated with gingival inflammation among adults with systemic sclerosis. | 23611650 |
| Inflammation, Sample Size Calculation, Scleroderma , Systemic Scleroderma | Altered Intercellular Communication | To identify factors associated with increased gingival inflammation in adults with systemic sclerosis (SSc, scleroderma). | 23611650 |
| Degenerative polyarthritis, Inflammation, Pain Distress Question | Altered Intercellular Communication | Cyclooxygenase-2 (COX-2) is a major prostaglandin E2 (PGE2) synthetic enzyme and is involved in the pathogenesis of chronic inflammation and pain in osteoarthritis (OA). | 23611898 |
| Inflammation, Anxiety Disorders | Altered Intercellular Communication | Anxiety disorders and inflammation in a large adult cohort. | 23612048 |
| Inflammation, Metabolic Syndrome X, Anxiety, CTCAE 3.0, Depression, CTCAE, Anxiety Disorders | Altered Intercellular Communication | Although anxiety disorders, like depression, are increasingly being associated with metabolic and cardiovascular burden, in contrast with depression, the role of inflammation in anxiety has sparsely been examined. | 23612048 |
| Inflammation, Anxiety Disorders | Altered Intercellular Communication | In conclusion, elevated inflammation is present in men with current anxiety disorders. | 23612048 |
| Inflammation, Necrosis | Altered Intercellular Communication | Thus, the laparotomic wound inflammation and necrosis was 24% less, eventration frequency was 4 times less and the acute respiratory failure was 43% less. | 23612338 |
| Inflammation, Osteoporosis | Altered Intercellular Communication | The impact of systemic inflammation, vitamin D insufficiency, air pollution, urban violence and poverty may have long-term bone detrimental outcomes in exposed paediatric populations as they grow older, increasing the risk of low bone mass and osteoporosis. | 23612523 |
| Inflammation, Non-Malignant | Altered Intercellular Communication | Semen quality and associated reproductive indicators in middle-aged males: the role of non-malignant prostate conditions and genital tract inflammation. | 23612791 |
| Inflammation, Non-Malignant | Altered Intercellular Communication | To compare the associations between non-malignant prostate conditions, genital tract inflammation, and reproductive function in middle-aged men. | 23612791 |
| Inflammation | Altered Intercellular Communication | Semen quality and associated reproductive indicators, seminal inflammation, and prostate-related pathologies were evaluated. | 23612791 |
| Communicable Diseases, Inflammation, Prostate | Altered Intercellular Communication | According to our data, one of the possible pathways for impaired reproductive quality in male subjects >45 years could be related to infection and inflammation in the genital tract with subsequent (partial) obstruction and damage of prostate and other male accessory glands. | 23612791 |
| Proteinuria, Nephritis, Lupus Erythematosus, Systemic | Altered Intercellular Communication | The inverse correlations observed between anti-IFI16 positivity, proteinuria and C3 hypocomplementaemia suggest that anti-IFI16 antibodies do not contribute to renal inflammation in SLE; indeed they may even prevent complement consumption. | 23612796 |
| Inflammation, Colorectal Carcinoma | Altered Intercellular Communication | The outcomes of colorectal cancer are determined by host factors, including systemic inflammation. | 23612884 |
| Malignant tumor of colon | Altered Intercellular Communication | The purpose of this study was to evaluate the prognostic significance of fibrinogen and inflammation-based scores, as markers of the inflammatory response, in colon cancer. | 23612884 |
| Cataract, Inflammation | Altered Intercellular Communication | Aqueous flare as a marker for inflammation and breakdown of the blood-retinal barrier is increased in patients with CME after cataract surgery. | 23613514 |
| Esophagitis | Altered Intercellular Communication | The cure rate of esophageal inflammation was 88.4% in the Nissen group and 67.7% in the Toupet group. | 23614820 |
| Inflammatory disease of mucous membrane, Toxic effect, Anorexia | Altered Intercellular Communication | No dose-limiting toxicities were reported; the most common drug-related adverse events were mucosal inflammation and anorexia. | 23615181 |
| Intraocular inflammation | Altered Intercellular Communication | Methotrexate proved effective in controlling intraocular inflammation and improving vision in 30 of 38 eyes (79%). | 23615343 |
| Inflammation, Benign prostatic hypertrophy, Structure of posterior cerebral artery | Altered Intercellular Communication | Because inflammation may be a common etiological risk factor between PCa and benign prostatic hyperplasia (BPH), the current study was conducted to investigate the association of rs103294 with BPH risk. | 23615473 |
| Inflammation, Structure of posterior cerebral artery | Altered Intercellular Communication | Our results support a common role of inflammation in the development of PCa and BPH. | 23615473 |
| MTA2 gene, Inflammation, borderline ovarian tumor | Altered Intercellular Communication | Our results suggest that a history of PID is associated with an increased risk of ovarian borderline tumors, which may support the hypothesis that inflammation is an etiological factor. | 23615817 |
| Inflammation, Aortic Stiffness | Altered Intercellular Communication | Effect of cardiorespiratory fitness on acute inflammation induced increases in arterial stiffness in older adults. | 23615823 |
| Inflammation | Altered Intercellular Communication | We tested the hypothesis that acute inflammation may cause arterial stiffening in older adults. | 23615823 |
| Inflammation | Altered Intercellular Communication | The high cardiorespiratory fitness group had an attenuated increase in PWV as compared to the low cardiorespiratory fitness group after acute inflammation (p < 0.05). | 23615823 |
| Inflammation, Aortic Stiffness | Altered Intercellular Communication | These findings show that acute inflammation may cause significant increases in arterial stiffness in older adults, but these increases were attenuated in the high cardiorespiratory fitness group as compared to the low cardiorespiratory fitness group. | 23615823 |
| Inflammation, Diabetes Mellitus, Non-Insulin-Dependent | Altered Intercellular Communication | We sought to analyse monocyte polarisation status in type 2 diabetes, which is characterised by chronic inflammation. | 23616239 |
| Inflammation, Amyloidosis, Malignant Neoplasms | Altered Intercellular Communication | Retroperitoneal amyloidosis has been described in a few case reports and is typically a secondary manifestation of inflammation or malignancy. | 23616327 |
| Inflammation, Observation Method - Coagulation, Adherence (attribute) | Altered Intercellular Communication | Hemodynamics, augmentation index (AIX), leukocyte cell surface adhesion markers, and plasma cytokines involved in vascular adherence, coagulation, and inflammation were measured before and after consumption of the milkshakes. | 23616512 |
| ARCN1 gene, Inflammation | Altered Intercellular Communication | To characterize the phenotypes of COPD according to high-resolution computed tomography (HRCT) findings; and to correlate HRCT scores obtained using the modified Bhalla scoring system with clinical and physiological indicators of systemic inflammation. | 23616965 |
| Inflammation, Exacerbation | Altered Intercellular Communication | Patients with HRCT findings had lower spirometric measurements and higher levels of inflammation, and reported more exacerbations in the previous year compared with patients with no findings on HRCT. | 23616965 |
| Inflammation, Malnutrition, MRSA colonization, Malignant Neoplasms, Comorbidity | Altered Intercellular Communication | History of malignancy and an increased Charlson Comorbidity Index were significant predictors for nasal MRSA carriers, whereas traditional risk factors for MRSA colonization or markers of inflammation or malnutrition were not able to discriminate. | 23617360 |
| Manufactured sign, Oculovestibuloauditory syndrome, Orbital Pseudotumor | Altered Intercellular Communication | Typically the ocular signs involve the anterior segment; however there are no descriptions of orbital inflammation associated with Cogan's syndrome. | 23617562 |
| Inflammation, Diplopia, Intermittent, Traumatic injury | Altered Intercellular Communication | We report the case of a 52-year-old man who presented with a 10-day history of right eye and eyelid inflammation and intermittent diplopia following blunt trauma to the right eyebrow. | 23617582 |
| Narrow Band Imaging, Inflammation, Dysplasia, Thrombopoietin Receptor Agonist LGD-4665, HGD gene | Altered Intercellular Communication | All areas on NBI-DF were classified into three easily distinguishable mucosal patterns: (i) regular pits with regular microvasculature (no dysplasia); (ii) irregular pits with irregular microvasculature (early cancer/high-grade dysplasia [HGD]); and (iii) equivocal, where the endoscopist was not sure about the pattern (this could be areas with increased brownish discoloration on NBI overview and dilated vasculature but no change in caliber on NBI-DF [likely inflammation or low-grade dysplasia: LGD]). | 23617668 |
| Inflammation, Dysplasia, Primary malignant neoplasm, Thrombopoietin Receptor Agonist LGD-4665, HGD gene | Altered Intercellular Communication | The 38 areas that appeared suspicious on NBI overview were also further assessed with NBI-DF: seven of seven were accurately predicted as harboring no dysplasia; nine areas were predicted as irregular, of which four harbored early cancer, one HGD, three LGD and one inflammation on final histopathology assessment. | 23617668 |
| Inflammation, Thrombopoietin Receptor Agonist LGD-4665 | Altered Intercellular Communication | Twenty-two areas were deemed to be equivocal (final histology: 18 LGD and four inflammation). | 23617668 |
| Intraocular inflammation, Uveitis | Altered Intercellular Communication | Periocular triamcinolone acetonide injections for control of intraocular inflammation associated with uveitis. | 23617776 |
| Intraocular inflammation, Uveitis | Altered Intercellular Communication | To describe the effectiveness of periocular corticosteroid injections for the control of intraocular inflammation associated with noninfectious uveitis. | 23617776 |
| Intraocular inflammation | Altered Intercellular Communication | Approximately half of the treated eyes had resolution of intraocular inflammation at 3 months after corticosteroid injection. | 23617776 |
| Inflammation, Ground Glass Opacity, Adenomatous hyperplasia, Lung Neoplasms, Bronchioloalveolar Adenocarcinoma | Altered Intercellular Communication | Lung tumors showing ground-glass opacities on high-resolution computed tomography indicate the presence of inflammation, atypical adenomatous hyperplasia, or localized bronchioloalveolar carcinoma. | 23618098 |
| Inflammation, Acute appendicitis NOS (disorder) | Altered Intercellular Communication | Interleukin 6 and lipopolysaccharide binding protein - markers of inflammation in acute appendicitis. | 23618571 |
| Inflammation, Appendicitis, CTCAE | Altered Intercellular Communication | Acute appendicitis illustrates inflammation development at digestive level and provides for a diagnostic and paraclinical exploration which continually upgrades. | 23618571 |
| Inflammation, Atherosclerosis, Carotid Intima-Media Thickness, Plaque, Atherosclerotic | Altered Intercellular Communication | Exposure to biomass fuel smoke has been associated with lung-mediated inflammation and oxidative stress, which may increase the risk of atherosclerosis as evaluated by carotid intima-media thickness (CIMT), carotid atherosclerotic plaque prevalence and blood pressure. | 23619984 |
| prostatitis | Altered Intercellular Communication | Fat boosts, while androgen receptor activation counteracts, BPH-associated prostate inflammation. | 23620238 |
| Inflammation | Altered Intercellular Communication | Chronic inflammation, a determinant pathogenic factor for BPH, is a putative link between the two conditions. | 23620238 |
| ETV3 wt Allele, prostatitis | Altered Intercellular Communication | In a multi-center cohort of BPH patients (n = 244) who underwent prostatectomy, we evaluated whether MetS is associated with prostatic inflammation in BPH specimens. | 23620238 |
| prostatitis | Altered Intercellular Communication | Among the different factors, oxidized low-density lipoprotein (oxLDL) showed the highest secretion of IL-8 (>10-fold)-a surrogate marker of prostate inflammation--as well as IL-6, and bFGF. | 23620238 |
| Granulomatous inflammation, Necrosis | Altered Intercellular Communication | A pathologic study confirmed that the nonenhancing center of the rim enhancement pattern corresponded to caseous or liquefied necrosis, and homogeneously enhanced portions corresponded to granulomatous inflammation. | 23620315 |
| Inflammation, Trauma, Nervous System | Altered Intercellular Communication | In chronically HIV+ adults with long-term viral suppression, current CVD risk, past CVD and age are independent factors for neuronal injury and inflammation. | 23620788 |
| Chronic inflammation, Cyclophosphamide/Vincristine/Dacarbazine Regimen | Altered Intercellular Communication | This suggests a tripartite model of HIV, CVD and age likely driven by chronic inflammation. | 23620788 |
| Inflammation, Psoriasis | Altered Intercellular Communication | It has been found that many of the triggering factors for psoriasis initiate inflammation by activation of NF-kB. | 23621342 |
| Inflammation, Psoriasis, Hyperplasia | Altered Intercellular Communication | The study has demonstrated that translocation of NF-kB in the epidermis and basal cells is responsible for two of the key pathological features of psoriasis, epidermal hyperplasia, and inflammation. | 23621342 |
| Granulomatous inflammation, Lymphadenitis, Lymphadenopathy | Altered Intercellular Communication | Tuberculous lymphadenitis is the most common form of lymphadenopathy; its main histopathological finding is granulomatous inflammation. | 23621948 |
| Airway structure | Altered Intercellular Communication | Oxidative stress, perhaps modulated by adipokines, may increase airway inflammation in obese individuals. | 23622004 |
| Inflammation, Asthma, Obesity | Altered Intercellular Communication | To characterize associations between obesity and asthma in a low-income, urban, minority community and evaluate adipokines, biomarkers of inflammation, and oxidant-antioxidant balance in association with asthma and obesity. | 23622004 |
| Inflammation | Altered Intercellular Communication | Our results suggest that IL-21, IL-23, and TGF-b1 may play an important role in the development of site-specific Th17 cell-mediated inflammation in BSRC, which underscore the importance of systemic therapy and offer new insights into the potential of targeted treatments. | 23622563 |
| Crohn Disease, Inflammation | Altered Intercellular Communication | To determine the accuracy of high-resolution magnetic resonance enterography (HR-MRE) against surgical and histopathology standards in Crohn's disease, and to determine quantitative MRE findings that can differentiate minor from advanced bowel inflammation. | 23622798 |
| Inflammation | Altered Intercellular Communication | Grading of inflammation was compared with MRE parameters for correlation and discriminating power. | 23622798 |
| Inflammation, Ulcer | Altered Intercellular Communication | Regression analysis showed deep and superficial ulcers, ER > 1.85 and mural thickness >4.5 mm were independent predictors of advanced inflammation. | 23622798 |
| Inflammation, Ulcer | Altered Intercellular Communication | Bowel ulcers, mural enhancement ratio >1.85 are strong predictors of advanced inflammation. | 23622798 |
| Inflammation, Neuromyelitis Optica | Altered Intercellular Communication | Complement activation after binding of an IgG autoantibody to aquaporin 4 (AQP4) is thought to be a major determinant of CNS inflammation and astrocytic injury in neuromyelitis optica. | 23623397 |
| Inflammation, Neoplasms | Altered Intercellular Communication | Because MRI evaluation showed that the vertebral disc was maintained in this case, the presence of a tumor rather than inflammation should have been suspected. | 23623631 |
| Ulcerative Colitis, Inflammatory disease of mucous membrane | Altered Intercellular Communication | Tacrolimus is effective for the maintenance of refractory UC and can deliver sustained improvement in mucosal inflammation. | 23623737 |
| Inflammation, Atrial Fibrillation | Altered Intercellular Communication | It has been reported that inflammation is associated with long-term maintenance of sinus rhythm after electrical cardioversion for non-valvular atrial fibrillation (AF). | 23623817 |
| Dimensions, Inflammation | Altered Intercellular Communication | Inflammation, in addition to left atrial dimension, may be associated with successful cardioversion using bepridil. | 23623817 |
| ARCN1 gene, Inflammation, Chronic Obstructive Airway Disease | Altered Intercellular Communication | Inflammation has a contributive role in the development and progression of chronic obstructive pulmonary disease (COPD).The present study was designed to determine the level and the distribution of C-reactive protein (CRP) and erythrocyte sedimentation rate (ESR) in COPD compared with controls. | 23624662 |
| Inflammation, Pulmonary Complication | Altered Intercellular Communication | Since inflammation has an important contribution in development of future pulmonary and extrapulmonary complications, serum CRP assessment will provide additional information beyond that achieved by conventional method of pulmonary function test. | 23624662 |
| Inflammation | Altered Intercellular Communication | BiA pacing is associated with reduction of ANP and markers of inflammation (hs-CRP, IL-6, and neopterin). | 23625090 |
| Inflammation, Vasogenic Edema, NRG1 protein, human, "Alzheimers Disease", Data types - Address | Altered Intercellular Communication | Cerebral amyloid angiopathy-related inflammation (CAA-ri) is characterized by vasogenic edema and multiple cortical/subcortical microbleeds, sharing several aspects with the recently defined amyloid-related imaging abnormalities (ARIA) reported in Alzheimer's disease (AD) passive immunization therapies. | 23625526 |
| Inflammation, Metabolic Syndrome X | Altered Intercellular Communication | Obesity-related immune mediated systemic inflammation was associated with the development of the metabolic syndrome by induction of the tryptophan (TRP)-kynurenine (KYN) pathway. | 23625535 |
| Inflammation | Altered Intercellular Communication | Biomarkers of rectal crypt proliferation and systemic inflammation are increased in morbidly obese patients compared with controls. | 23625552 |
| Inflammation, Fibrosis Assessment, Cardiovascular Diseases | Altered Intercellular Communication | In cardiovascular diseases including pressure overload-induced HF, perivascular inflammation and cardiac fibrosis are, in part, mediated by monocyte chemoattractant protein (MCP)1-driven monocyte migration. | 23625718 |
| Inflammation | Altered Intercellular Communication | rhIL-10-treated rat incisions healed with decreased inflammation, better scar histology, and better macroscopic scar appearance. | 23627460 |
| Inflammation, Cicatrization | Altered Intercellular Communication | IL-10 is an important cytokine in wound healing and its suppression of inflammation and scarring is demonstrated in mice and rats with a translational effect in humans. | 23627460 |
| Sepsis, Inflammation | Altered Intercellular Communication | A cut-off value of 98 ng/mL distinguished sepsis from systemic inflammation with high sensitivity (0.77) and specificity (0.79). | 23627612 |
| Inflammation | Altered Intercellular Communication | Computed tomography-guided biopsy of the bone was completed and revealed chronic inflammation with hematopoietic elements. | 23628193 |
| Inflammation, Fibrosis Assessment, Calcinosis, Pancreatitis Necrotizing | Altered Intercellular Communication | The presence of chronic inflammation, fibrosis, and calcification would suggest that this process had been present before birth.We report a 27-day-old newborn with acute necrotizing aortitis. | 23629409 |
| Inflammation, Colorectal Carcinoma | Altered Intercellular Communication | Higher levels of physical activity are associated with lower colorectal carcinoma incidence and mortality, perhaps through influencing energy balance, cellular prosta7 systemic inflammation. | 23629521 |
| Inflammation, Pain Distress Question | Altered Intercellular Communication | The clycoxygenase (COX) enzyme forms locally active prostaglandins responsible for producing inflammation and pain. | 23629578 |
| Orbital Pseudotumor | Altered Intercellular Communication | Serum immunoglobulin G4 (IgG4)-related systemic disease is a newly found entity and should be considered as a further differential diagnosis to the big pool of unspecific orbital inflammation. | 23629783 |
| Orbital Pseudotumor | Altered Intercellular Communication | We retrospectively analyzed all patients with the diagnosis IgG4-related orbital inflammation who were examined in our outpatient clinic. | 23629783 |
| Orbital Pseudotumor | Altered Intercellular Communication | Extended unspecific orbital inflammation, especially when bilateral and associated with systemic disease should be considered to be IgG4-related. | 23629783 |
| Proteinuria, Inflammation, Hematuria, CTCAE, Anemia | Altered Intercellular Communication | On admission, laboratory findings showed signs of inflammation, anemia, proteinuria, and hematuria. | 23631304 |
| Uterine Cervicitis, Infection | Altered Intercellular Communication | Cervicitis is a syndrome of cervical inflammation and a common condition in female sex workers (FSW), a subpopulation vulnerable to sexually transmitted infections. | 23631602 |
| Kidney Failure, Chronic, Inflammation, Sarcopenia, Bipolar Disorder | Altered Intercellular Communication | We investigated the prevalence of sarcopenia in elderly patients with end-stage renal disease (ESRD) and its relationship with various markers of nutrition, cognitive function, depressive symptoms, inflammation and b2-microglobulin. | 23631844 |
| Inflammation, Fibrosis Assessment, SDSL gene | Altered Intercellular Communication | Inflammation and fibrosis indicate targets for further studies in the pathogenesis of CSDH. | 23632762 |
| Atherosclerosis | Altered Intercellular Communication | Resistin is a novel adipokine that is suggested to be involved in inflammatory conditions and atherosclerosis. | 23633273 |
| Inflammation, Hematoma, Granulation finding, Mesenteric Cyst | Altered Intercellular Communication | Histopathological investigation showed a mesenteric cyst incorporating a hematoma and tissue with signs of chronic inflammation and granulation. | 23633278 |
| Inflammation, Hematoma, Appendicitis, CTCAE, Peritonitis | Altered Intercellular Communication | In the presented case presented hematoma formation and chronic inflammation had presumably induced peritonitis and clinical signs of appendicitis. | 23633278 |
| vascular inflammations, Sleep Disorders | Altered Intercellular Communication | Vascular inflammation and sleep disordered breathing in a community-based cohort. | 23633759 |
| vascular inflammations | Altered Intercellular Communication | The pathophysiologic mechanisms remain unclear, but enhanced vascular inflammation is implicated. | 23633759 |
| Bacteremia, Inflammation, Acute Disease | Altered Intercellular Communication | In contrast, patients with a pulmonary infiltrate or bacteraemia had more inflammation (median C-reactive protein: no infiltrate and no bacteraemia 82 mg/L vs. infiltrate without bacteraemia 163 mg/L vs. bacteraemia 316 mg/L) and higher acute disease severity scores. | 23634696 |
| Bacteremia, Inflammation, Lower respiratory tract infection, Acute Disease | Altered Intercellular Communication | Still, there is a clinically important outcome gradient from LRTI patients with pneumococcal isolation only to those with detected pulmonary infiltrate or bacteraemia which is partly mediated by higher acute disease severity and inflammation. | 23634696 |
| Inflammation, Primary malignant neoplasm | Altered Intercellular Communication | Toll-like receptors (TLRs) and the transcription factor nuclear factor-kB (NFkB) are important in inflammation and cancer. | 23634849 |
| Inflammation, Fluid overload, Chronic Kidney Diseases | Altered Intercellular Communication | Accumulating evidence suggests an association between body volume overload and inflammation in chronic kidney diseases. | 23635012 |
| Inflammation, Atherosclerosis | Altered Intercellular Communication | Pioglitazone, an anti-diabetic agent that improves insulin resistance, was also reported to decrease inflammation and protect against atherosclerosis. | 23635096 |
| Inflammation | Altered Intercellular Communication | Those at highest risk for conversion are elderly male patients with prior abdominal surgery who present emergently with laboratory evidence of biliary inflammation. | 23635600 |
| Eczematous drug eruption, Inflammation, Dermatitis, Eczema | Altered Intercellular Communication | A subgroup analysis on cases whose skin biopsy specimens showed a pattern of inflammation that is conventionally thought to be associated with eczematous drug eruptions (ie, eczematous and interface dermatitis) was also performed. | 23636109 |
| Inflammation | Altered Intercellular Communication | SIRT1 and PPARg, host defenses regulating inflammation and metabolic functions, are suppressed under chronic high oxidant stress and inflammation (OS/Infl) conditions. | 23636469 |
| Pain Distress Question, Fibromyalgia, Allodynia, Hyperalgesia, Pain Disorder | Altered Intercellular Communication | Fibromyalgia is a chronic widespread pain disorder in which, the neurogenic origin of the pain, featured by allodynia and hyperalgesia, results from an imbalance in the levels of neurotransmitters and consequently of the peripheral pro- and anti-inflammatory mediators. | 23636794 |
| Inflammation, Cyclophosphamide/Vincristine/Dacarbazine Regimen, Pathology, Cardiovascular Diseases | Altered Intercellular Communication | Low grade systemic inflammation (LGSI) as well as androgen deficiency has in older men been associated with several pathologies, including cardiovascular disease (CVD). | 23637840 |
| Inflammation | Altered Intercellular Communication | These results demonstrated that local application of H(H2O)m may prevent UV-induced skin inflammation and can modulate intrinsic skin aging and photoaging processes. | 23637886 |
| Inflammation, Swelling, Synovitis | Altered Intercellular Communication | Concordance between swelling joint by clinical examination, synovitis thickening by B-mode (grade 1 or higher) and inflammation by power Doppler (grade 1 or higher) was assessed by computing the kappa coefficient. | 23639595 |
| Inflammation, Chronic Kidney Diseases | Altered Intercellular Communication | Acute and sub-acute effect of ferric carboxymaltose on inflammation and adhesion molecules in patients with predialysis chronic renal failure. | 23640119 |
| Inflammation, Endothelial dysfunction | Altered Intercellular Communication | Treatment with parenteral iron causes oxidative stress, inflammation and endothelial dysfunction. | 23640119 |
| Inflammation | Altered Intercellular Communication | In contrast, FDG uptake in chronic arthritic joint inflammation was diffuse and mild, without significant change over time, while FDG uptake in nonarthritic joints was at near-background level with decreased activity on delayed images. | 23640221 |
| Granuloma, Inflammation | Altered Intercellular Communication | Our finding indicates differential FDG uptake and clearance in active granulomas versus chronic inflammation. | 23640221 |
| Inflammation, Cyclophosphamide/Vincristine/Dacarbazine Regimen, Cardiovascular Diseases | Altered Intercellular Communication | Evidence suggests that chronic low-grade inflammation and oxidative stress are related to cardiovascular disease (CVD) and mortality. | 23640499 |
| Inflammation, Tumor necrosis | Altered Intercellular Communication | We examined 11 established and novel biomarkers representing inflammation and oxidative stress (C-reactive protein, fibrinogen, interleukin-6, intercellular adhesion molecule-1, lipoprotein-associated phospholipase-A2 [mass and activity], monocyte chemoattractant protein-1, myeloperoxidase, CD40 ligand, P-selectin, and tumor necrosis factor receptor II [TNFRII]) in relation to incident major CVD and mortality in the community. | 23640499 |
| APP gene, Inflammation | Altered Intercellular Communication | These findings demonstrated lymphatic vessel involvement in end-stage AAA disease, which was associated with the degree of inflammation, and confirmed the involvement of neovascularization. | 23640666 |
| Inflammation, Diabetes Mellitus | Altered Intercellular Communication | Weekly EPO dose per kg of dry body weight was positively related to both VEGF-A and angiogenin, whereas no relation was detected among VEGF-A or angiogenin and hemoglobin, inflammation or presence of diabetes mellitus. | 23640951 |
| Inflammation, Diabetes Mellitus | Altered Intercellular Communication | These relations among EPO dose and VEGF-A or angiogenin remained after adjustment for hemoglobin concentration or inflammation or presence of diabetes mellitus. | 23640951 |
| Inflammation, Demographics Domain, Cardiovascular Diseases, Diabetes Mellitus | Altered Intercellular Communication | Inflammation is a common feature in the majority of cardiovascular disease, including Diabetes Mellitus (DM). | 23642086 |
| Communicable Diseases, Inflammatory abnormality of the eye | Altered Intercellular Communication | Patients were tested for all endemic infectious diseases that can cause ocular inflammation by serology or molecular diagnostics. | 23642374 |
| Retinitis | Altered Intercellular Communication | The FFA revealed areas of retinal inflammation with indistinct borders, vascular and optic disc leakage, vessel wall staining, or capillary nonperfusion. | 23642374 |
| Choroiditis, diabetic | Altered Intercellular Communication | Indocyanine green angiography confirmed choroidal inflammation in 1 of the patients who was diabetic. | 23642374 |
| Inflammation, Atrophic retina, Layer of retina | Altered Intercellular Communication | The OCT scan of the macula revealed inner retinal layer edema in active inflammation and retinal atrophy in late stage. | 23642374 |
| Inflammation, Cystic Fibrosis | Altered Intercellular Communication | Eighteen patients with fibrotic disease and 19 patients with inflammation were examined. | 23643057 |
| Inflammation, Fibrosis Assessment | Altered Intercellular Communication | The fibrosis group had lower blood volume (0.9 vs. 3.4 mL per 100 mL tissue; p = 0.001) and flow (22.6 vs. 45.3 mL/min per 100 mL tissue; p = 0.003) compared with the inflammation group. | 23643057 |
| Neurogenic Inflammation, Dermatologic disorders, Rosacea | Altered Intercellular Communication | Rosacea is a common skin disease, involving neurogenic inflammation and neurovascular dysregulation. | 23643255 |
| Migraine Disorders, Inflammation | Altered Intercellular Communication | Migraine has been associated with vascular changes and sterile inflammation. | 23643255 |
| Diabetes Mellitus, Non-Insulin-Dependent | Altered Intercellular Communication | Inflammation markers predict zinc transporter gene expression in women with type 2 diabetes mellitus. | 23643522 |
| Inflammation, Demographics Domain, Diabetes Mellitus, Non-Insulin-Dependent | Altered Intercellular Communication | The pathology of type 2 diabetes mellitus (DM) often is associated with underlying states of conditioned zinc deficiency and chronic inflammation. | 23643522 |
| Inflammation, Cerebral Ischemia | Altered Intercellular Communication | Pro-inflammatory cytokine network in peripheral inflammation response to cerebral ischemia. | 23643982 |
| Inflammation, Acute cerebral ischemia | Altered Intercellular Communication | The key circulating pro-inflammatory cytokines and their interaction in peripheral inflammation after acute cerebral ischemia are poorly understood. | 23643982 |
| Inflammation, Depression, CTCAE, Cerebral Ischemia | Altered Intercellular Communication | Pro-inflammatory cytokines up-regulation in plasma and compensatory immunity depression in leukocyte involve in peripheral inflammation response to cerebral ischemia. | 23643982 |
| Inflammation, Pancreatitis, Malnutrition, Liver Cirrhosis | Altered Intercellular Communication | Cirrhosis and chronic pancreatitis (CP) are accompanied by inflammation and malnutrition. | 23644391 |
| Inflammation | Altered Intercellular Communication | Cell cycle regulation, apoptosis, oxidative stress and inflammation response play critical roles in the development of smoking-induced lung cancer. | 23644744 |
| Inflammation | Altered Intercellular Communication | The imbalance between inflammation and anti-inflammation may be part of the mechanism. | 23645243 |
| Autoimmune Hypophysitis | Altered Intercellular Communication | Autoimmune hypophysitis (AH) is commonly believed to be a rare chronic inflammatory condition of the pituitary gland. | 23645305 |
| Inflammation, Respiration Disorders, Hypoxia | Altered Intercellular Communication | Serum uric acid is increased in respiratory disease, especially in the presence of hypoxia and systemic inflammation. | 23645404 |
| ARCN1 gene, Inflammation, Chronic Obstructive Airway Disease | Altered Intercellular Communication | Chronic obstructive pulmonary disease (COPD) is associated with systemic inflammation and oxidative stress. | 23645408 |
| Inflammation, Sleep Apnea, Central, Heart failure, Cardiac Arrhythmia | Altered Intercellular Communication | Central sleep apnoea and inflammation are independently associated with arrhythmia in patients with heart failure. | 23645499 |
| Malnutrition, HD Term Type, Inflammation | Altered Intercellular Communication | Resistance to erythropoietin (EPO) treatment has been associated with inflammation and malnutrition in hemodialysis (HD) patients. | 23645578 |
| Inflammation, Malnutrition, Depression, CTCAE, Bipolar Disorder | Altered Intercellular Communication | Depression has also been associated with both inflammation and malnutrition; however, the specific relationship between depressive symptoms and EPO resistance is not known. | 23645578 |
| Inflammation | Altered Intercellular Communication | Telomerase activity was independently associated with LTL (p = 0.007) and negatively modulated by inflammation and oxidative stress. | 23646142 |
| Inflammation | Altered Intercellular Communication | According to the last reports, the role of chronic minimal inflammation in colon mucosa is becoming more relevant. | 23646443 |
| Inflammation | Altered Intercellular Communication | Mild inflammation of colonic mucosa in lamina propria was observed in 92% patients, 34% presented other inflammatory cells. | 23646443 |
| Inflammation, Ichthyosis Bullosa of Siemens | Altered Intercellular Communication | Low grade inflammation of lamina propria in colon was observed among patients with IBS. | 23646443 |
| Inflammation, Chronic disease | Altered Intercellular Communication | To test the hypothesis that changes in air pollution levels are associated with changes in biomarker levels reflecting inflammation, hemostasis, oxidative stress, and autonomic tone, we recruited and retained 125 nonsmoking adults (19 to 33 years old) free of cardiorespiratory and other chronic diseases. | 23646463 |
| Inflammatory disease of mucous membrane | Altered Intercellular Communication | The perioperative application of BLFNI could alleviate postoperative mucosal inflammation, shorten the cavity cleaning time, speed up the process of epithelization, improve the QOL, and elevate the operative efficacy. | 23646471 |
| Inflammation | Altered Intercellular Communication | Nucleic acid sensing has emerged as one of the important components of the immune system triggering inflammation. | 23646855 |
| Inflammation | Altered Intercellular Communication | This study highlights a possible role for nucleic acid receptors in periodontal inflammation. | 23646855 |
| Inflammation, Asthma | Altered Intercellular Communication | We suggest that the studied cytokines, with a stronger indication for leptin, can elicit asthmatic inflammation in obese phenotype of asthma that affects more frequently women. | 23648099 |
| Neurodegenerative Disorders, Inflammation, Abnormality of mitochondrial metabolism, "Alzheimers Disease", Data types - Address | Altered Intercellular Communication | These age-related neurodegenerative diseases including Alzheimer's disease (AD) are associated with mitochondrial dysfunction, oxidative stress, and inflammation. | 23648515 |
| Fatigue | Altered Intercellular Communication | We assessed serum and fecal markers of intestinal inflammation/injury and immune activation, and indices of fatigue. | 23648697 |
| Inflammation, Pancreatitis, Haemoconcentration | Altered Intercellular Communication | Early measures of hemoconcentration and inflammation are predictive of prolonged hospitalization from post- endoscopic retrograde cholangiopancreatography pancreatitis. | 23648842 |
| Inflammation | Altered Intercellular Communication | Senescent cells also secrete inflammatory cytokines such as IL-6, which promote age-associated inflammation and pathology. | 23649808 |
| Inflammation | Altered Intercellular Communication | Our findings identify senescence as a novel biological setting in which HMGB1 functions and link HMGB1 redistribution to p53 activity and senescence-associated inflammation. | 23649808 |
| Chronic lymphocytic inflammation, Pontine structure, B-Cell Lymphomas | Altered Intercellular Communication | Fatal B-cell lymphoma following chronic lymphocytic inflammation with pontine perivascular enhancement responsive to steroids. | 23649857 |
| Chronic lymphocytic inflammation, Pontine structure, Clippers | Altered Intercellular Communication | Recent reports on chronic lymphocytic inflammation with pontine perivascular enhancement responsive to steroids (CLIPPERS) suggest that patients who have a relapse respond very well and that disease progression can be avoided if timely corticosteroid therapy is started. | 23649857 |
| Inflammation | Altered Intercellular Communication | DES showed an increase in inflammatory cytokines in the late phase after implantation in comparison with patients who received BMS, suggesting late-stage inflammation. | 23649933 |
| Presenile dementia, Inflammation, Bipolar Disorder | Altered Intercellular Communication | Longitudinal relationship of low leisure satisfaction but not depressive symptoms with systemic low-grade inflammation in dementia caregivers. | 23650246 |
| Inflammation, Depression, CTCAE, Bipolar Disorder | Altered Intercellular Communication | We hypothesized that both elevated depressive symptoms and a behavioral correlate of depression, low leisure satisfaction, are associated with systemic inflammation. | 23650246 |
| Inflammation, Bipolar Disorder | Altered Intercellular Communication | Depressive symptoms did not mediate the relationship between leisure satisfaction and inflammation. | 23650246 |
| Inflammation, Leukemogenesis, Leukemia, Myelocytic, Acute | Altered Intercellular Communication | Although high miR-155 expression was not associated with a distinct microRNA expression profile, it was associated with a gene expression profile enriched for genes involved in cellular mechanisms deregulated in AML (eg, apoptosis, nuclear factor-kB activation, and inflammation), thereby supporting a pivotal and unique role of this microRNA in myeloid leukemogenesis. | 23650424 |
| Inflammation, Chronic Kidney Diseases | Altered Intercellular Communication | Despite the fact that low plasma zinc (Zn) levels play important roles in the oxidative stress, the relationships between lipid peroxidation and inflammation biomarkers with low plasma Zn levels have not been investigated in chronic kidney disease (CKD) patients. | 23650973 |
| HD Term Type, Inflammation | Altered Intercellular Communication | In conclusion, reduced Zn levels were associated with lipid peroxidation and inflammation, and we confirm here in a Brazilian cohort of HD patients that inflammation markers are strong predictors of CV death. | 23650973 |
| Inflammation, GDC AJCC Clinical Stage Terminology | Altered Intercellular Communication | Our study shows that ACS associates with low HDL-C and biomarkers of oxidative stress and inflammation. | 23651064 |
| Autoimmune Diseases, Inflammation, TRPV6 gene, Tropical Spastic Paraparesis | Altered Intercellular Communication | Moreover, because abrogation of OX40 signals ameliorates chronic inflammation in animal models of autoimmune disease, novel monoclonal antibodies against OX40 may offer a potential treatment for HTLV-1-associated diseases such as ATL and HAM/TSP. | 23651542 |
| Colitis, Inflammation, Diarrhea, Irritable Bowel Syndrome | Altered Intercellular Communication | Low prevalence of 'classical' microscopic colitis but evidence of microscopic inflammation in Asian irritable bowel syndrome patients with diarrhoea. | 23651739 |
| Inflammation, Ichthyosis Bullosa of Siemens | Altered Intercellular Communication | There is increasing evidence for the role of microscopic inflammation in patients with IBS. | 23651739 |
| Inflammation, Ichthyosis Bullosa of Siemens, Diarrhea, Colitis | Altered Intercellular Communication | We aimed to examine the prevalence of microscopic colitis and inflammation in Malaysian IBS patients with diarrhoea (IBS-D). | 23651739 |
| Inflammation | Altered Intercellular Communication | However, the IBS-D patients had a higher prevalence of moderate microscopic inflammation (n = 11, 14.9%) compared to controls (n = 1, 2.2%) (p = 0.005). | 23651739 |
| Inflammation, Colitis | Altered Intercellular Communication | 'Classical' microscopic colitis is uncommon in Malaysian patients with IBS-D but a significant number of adults showed evidence of microscopic inflammation. | 23651739 |
| Inflammation, Obesity | Altered Intercellular Communication | In a group of school-aged Mexican children, obesity increases cardiovascular risk and inflammation. | 23652186 |
| Inflammation, Cardiovascular system alteration, Obesity | Altered Intercellular Communication | More research is needed in order to explore the role of subclinical inflammation in the development of cardiovascular alterations that have already been described in Mexican children with obesity. | 23652186 |
| vascular inflammations | Altered Intercellular Communication | Peroxisome proliferator-activated receptor g (PPARg) is a ligand-activated transcription factor that regulates the gene expression of the key proteins involved in lipid metabolism, vascular inflammation, and proliferation. | 23652363 |
| Inflammation | Altered Intercellular Communication | Social isolation and adult mortality: the role of chronic inflammation and sex differences. | 23653312 |
| Inflammation | Altered Intercellular Communication | A high-risk fibrinogen level and cumulative inflammation burden may be particularly important in this link. | 23653312 |
| Hemorrhagic, Inflammation | Altered Intercellular Communication | Histopathological analysis revealed seminoma of the right testis and dilated right vesicula seminalis filled with hemorrhagic fluid and sings of chronic inflammation. | 23654019 |
| Inflammation, Numerous, Lupus Erythematosus, Systemic, Autoimmune Diseases, Lupus Erythematosus | Altered Intercellular Communication | Systemic lupus erythematosus (SLE) is a polymorphic and multigenic autoimmune disease that evolves into progressive and chronic inflammation of multiple joints and organs. | 23656347 |
| Inflammation, Prostate carcinoma | Altered Intercellular Communication | Recent advances demonstrate a relationship between chronic/recurrent inflammation and prostate cancer (PCA). | 23657238 |
| Malignant Biliary Obstruction | Altered Intercellular Communication | Usefulness of an inflammation-based prognostic score (mGPS) for predicting survival in patients with unresectable malignant biliary obstruction. | 23657751 |
| Primary malignant neoplasm | Altered Intercellular Communication | An inflammation-based prognostic score, the modified Glasgow Prognostic Score (mGPS), has been established as a useful tool for predicting postoperative outcome in patients with cancer. | 23657751 |
| Inflammation, Malignant Neoplasms | Altered Intercellular Communication | Monocyte chemoattractant protein-1 (MCP-1) and its receptor CC chemokine receptor 2 (CCR2) play a major role in inflammation and proliferation of cancers. | 23657965 |
| Inflammation, Diabetic Angiopathies, Chronic Kidney Diseases | Altered Intercellular Communication | PTX3 may be involved in adipose tissue-orchestrated mechanisms that are restricted to the uremic milieu and modify inflammation and vascular complications in CKD patients. | 23658833 |
| Inflammation, Anemia, Choline Dehydrogenase, Mitochondrial | Altered Intercellular Communication | Anemia developing in CHD patients may cause not only inflammation but also depletion of iron reserves. | 23659067 |
| Inflammation, Rheumatic Fever | Altered Intercellular Communication | Increased ischaemia-modified albumin is associated with inflammation in acute rheumatic fever. | 23659227 |
| Inflammation, Rheumatic Fever | Altered Intercellular Communication | The increased level of ischaemia-modified albumin in children with acute rheumatic fever seems to be associated with inflammation. | 23659227 |
| Axonal degeneration, Inflammation | Altered Intercellular Communication | A better understanding of the influence of the inflammation on sodium channels mediated axonal degeneration could offer therapeutic perspectives. | 23659577 |
| Inflammation, Chronic Obstructive Airway Disease | Altered Intercellular Communication | Elevated circulating cytotoxic T lymphocyte-associated antigen-4 levels are related to lung function and inflammation in chronic obstructive pulmonary disease. | 23659585 |
| Inflammation | Altered Intercellular Communication | Cytotoxic T lymphocyte-associated antigen-4 (CTLA-4) is involved in immune and inflammation regulation. | 23659585 |
| NCI CTEP SDC Myelodysplastic Syndrome Sub-Category Terminology, Inflammation, Cytopenia, Leukemia, Large Granular Lymphocytic | Altered Intercellular Communication | The final diagnoses included 17 patients with myelodysplastic syndrome, 9 patients with pure red cell aplasia (non-large granular lymphocytosis [LGL] in etiology], 15 patients with LGL (eight of whom had a single-lineage cytopenia only, whereas the other seven had multilineage cytopenias), and 7 patients with cytopenias associated with systemic inflammation from autoimmune conditions. | 23660070 |
| Inflammation, Cytopenia, Pancytopenia | Altered Intercellular Communication | Our data suggest that low BFU-E growth (less than 10 BFU-E per 10(5) marrow mononuclear cells) helps to exclude LGL, pure red cell aplasia, or cytopenias associated with systemic inflammation as a cause of pancytopenia with a sensitivity of 96.8%, specificity of 76.5%, and a predictive value of 88.2% (p = 0.0001). | 23660070 |
| Pain Distress Question, Acute inflammation | Altered Intercellular Communication | The pain and postoperative inflammation were successfully controlled with an analgesic and an anti-inflammatory drug. | 23660343 |
| Inflammation, Malignant neoplasm of sigmoid colon, Crohn Disease | Altered Intercellular Communication | After surgery, histopathology revealed acute/chronic diverticular inflammation only in 29 cases, and superimposed sigmoid cancer (n = 2) or Crohn's disease (n = 1) in 3 patients with a DDSS of 4. | 23660775 |
| Inflammation | Altered Intercellular Communication | The relationship between inflammation, degeneration (IVD), and cytokine upregulation is well established, but other mediators of the inflammatory cascade are not well characterized. | 23660804 |
| Carcinogenesis, Malignant Neoplasms | Altered Intercellular Communication | Although the role of microRNAs (miRs) in GBC have not been well documented, miR-155 is known to be associated with inflammation-associated carcinogenesis in various types of cancers. | 23660842 |
| Inflammation, Exfoliation Syndrome, Endothelial dysfunction | Altered Intercellular Communication | Serum YKL-40 levels as a novel marker of inflammation and endothelial dysfunction in patients with pseudoexfoliation syndrome. | 23661157 |
| Inflammation, Tuberculosis | Altered Intercellular Communication | The histology revealed caseating, transmural granulomatous inflammation consistent with tuberculosis. | 23661658 |
| Inflammation, Lupus Erythematosus | Altered Intercellular Communication | Invariant natural killer T cells are enriched at the site of cutaneous inflammation in lupus erythematosus. | 23664188 |
| Lupus Erythematosus | Altered Intercellular Communication | The deficiency in circulating iNKT cells in cutaneous lupus erythematosus is associated with an increase of iNKT cells at the site of cutaneous inflammation. | 23664188 |
| Malignant neoplasm of urinary bladder, Inflammation, Pyuria | Altered Intercellular Communication | To evaluate the significance of inflammation in non-muscle-invasive bladder cancer (NMIBC), we assessed the presence of pyuria at time of diagnosis. | 23664207 |
| Inflammation, Pterygium Of Conjunctiva And Cornea | Altered Intercellular Communication | Ocular demodicosis is a risk factor for pterygium recurrence, especially for conjunctival recurrence, presumably by perpetuating chronic inflammation mediated by T-helper (Th)17 lymphocytes. | 23664471 |
| Oropharyngeal, Inflammation, Lemierre Syndrome, Thrombosis | Altered Intercellular Communication | Severe oropharyngeal infection can result in Lemierre's disease, a syndrome with high mortality secondary to inflammation and thrombosis of cervical and intracranial veins with involvement of contiguous structures; however arterial involvement is rare. | 23664903 |
| Inflammation, Observation Method - Coagulation | Altered Intercellular Communication | Aggregate risk score based on markers of inflammation, cell stress, and coagulation is an independent predictor of adverse cardiovascular outcomes. | 23665099 |
| Inflammation, Steatohepatitis, Fibrosis Assessment, Fatty degeneration, Non-alcoholic Fatty Liver Disease, Fatty Liver Disease | Altered Intercellular Communication | Disease progression in non-alcoholic fatty liver disease (NAFLD) is not well understood and there is controversy about whether non-alcoholic fatty liver (NAFL, i.e., steatosis alone or with mild inflammation not qualifying for steatohepatitis) can evolve towards steatohepatitis (NASH) with fibrosis. | 23665288 |
| Inflammation, Fibrosis Assessment, Fatty degeneration | Altered Intercellular Communication | Patients with mild lobular inflammation or any degree of fibrosis were at higher risk of progression than those with steatosis alone. | 23665288 |
| Inflammation, Fibrosis Assessment, Fatty degeneration | Altered Intercellular Communication | Even mild inflammation or fibrosis could substantially increase the risk of progression when compared to steatosis alone. | 23665288 |
| Inflammation, Glycation End Products, Advanced, Atherosclerosis | Altered Intercellular Communication | High sensitivity C-reactive protein (hsCRP) and advanced glycation end-products (AGEs) have been proposed as mediators in inflammation and atherosclerosis. | 23665412 |
| Inflammation, Colitis | Altered Intercellular Communication | Oral administration of d-limonene controls inflammation in rat colitis and displays anti-inflammatory properties as diet supplementation in humans. | 23665426 |
| vascular inflammations | Altered Intercellular Communication | Lectin-like oxidized low-density lipoprotein receptor-1 plays an important role in vascular inflammation in current smokers. | 23665840 |
| vascular inflammations | Altered Intercellular Communication | Smoking induces vascular inflammation and increases the risk of cardiovascular events. | 23665840 |
| Inflammation, Atherosclerosis | Altered Intercellular Communication | These findings suggest that LOX-1 may therefore play an important role in the onset of smoking-induced inflammation and atherosclerosis in humans. | 23665840 |
| Inflammation, Endothelial dysfunction, atherosclerotic | Altered Intercellular Communication | The ApoB/A1 ratio was associated with the d-ROMs, a marker of oxidative stress, endothelial dysfunction and inflammation, and could be useful as a residual atherosclerotic risk marker to help prevent CAD in statin-treated patients. | 23665841 |
| Inflammation, Infection | Altered Intercellular Communication | The mechanism responsible for such harmful association is probably indirect, and involves the weakening of platelet-neutrophil-endothelial crosstalk necessary to combat infections, and/or keep inflammation from spreading. | 23665886 |
| Hepatitis | Altered Intercellular Communication | Indeed, NKp46-rich NK populations were the most activated, correlating closely with the severity of liver inflammation. | 23665989 |
| Inflammation, Eisenmenger Complex | Altered Intercellular Communication | Inflammation may be an important contributing factor to the progression of Eisenmenger syndrome (ES). | 23666048 |
| Inflammation, Coronary Artery Disease | Altered Intercellular Communication | Neutrophil to lymphocyte ratio (NLR) is widely used as a marker of inflammation and an indicator of cardiovascular outcomes in patients with coronary artery disease. | 23666299 |
| Inflammation, Somnolence, Hemorrhagic, Cessation of life, Kidney Failure | Altered Intercellular Communication | The primary risk factors associated to death were kidney or respiratory failure, somnolence, hemorrhagic manifestations and a syndrome of systemic inflammation. | 23666663 |
| Inflammation | Altered Intercellular Communication | Age-related telomere uncapping is associated with cellular senescence and inflammation independent of telomere shortening in human arteries. | 23666675 |
| Inflammation, Arteritis | Altered Intercellular Communication | Arterial telomere dysfunction may contribute to chronic arterial inflammation by inducing cellular senescence and subsequent senescence-associated inflammation. | 23666675 |
| Inflammation, Primary malignant neoplasm | Altered Intercellular Communication | Lysophosphatidic acid (LPA) is a bioactive lipid that binds to a group of cell surface G protein-coupled receptors (LPA receptors 1-6 [LPA1-6 ]) and has been implicated as an important mediator of angiogenesis, inflammation, and cancer growth. | 23666827 |
| Abscess, Inflammation, Malignant Neoplasms | Altered Intercellular Communication | Ultrasound scan revealed a necrotic abscess suspicious of malignancy and biopsy showed evidence of chronic inflammation. | 23667218 |
| Inflammation, MS gene, Nerve injury | Altered Intercellular Communication | Intense inflammation and nerve damage in early multiple sclerosis subsides at older age: a reflection by cerebrospinal fluid biomarkers. | 23667585 |
| Inflammation, Trauma, Nervous System, Axonal loss, Physical disability, MS gene | Altered Intercellular Communication | The extent of neuronal injury and axonal loss are associated with the degree of CNS inflammation and determine physical disability in multiple sclerosis (MS). | 23667585 |
| nervous system disorder, Inflammation | Altered Intercellular Communication | Levels of matrix metalloproteinase 9 (MMP9), chemokine (C-X-C motif) ligand 13 (CXCL13), osteopontin (OPN) and neurofilament-light chain (NFL) were measured by ELISA in 548 subjects comprising different MS subtypes (relapsing-remitting, secondary progressive and primary progressive), clinically isolated syndrome and persons with other neurological diseases with or without signs of inflammation/infection. | 23667585 |
| Renal Insufficiency, Inflammation, Calcinosis, Vascular calcification | Altered Intercellular Communication | The case demonstrates that while mechanisms of vascular calcification are poorly understood, inflammation per se might be sufficient to mediate increased mineral stress leading to vessel calcification, even in the absence of renal impairment. | 23668269 |
| Inflammation, Diabetes Mellitus, Non-Insulin-Dependent | Altered Intercellular Communication | The oat-enriched diet had a modest impact on lipid lowering, but did not impact on oxidative stress or inflammation in these volunteers with Type 2 diabetes. | 23668675 |
| Gastrointestinal inflammation | Altered Intercellular Communication | LCN2 is a putative biomarker in faeces for intestinal inflammation, different from calprotectin due to its epithelial site of synthesis. | 23668802 |
| Pneumonitis | Altered Intercellular Communication | As quantified by blinded scoring of lung pathology, P. acnes-induced granulomatous pulmonary inflammation was markedly attenuated in TLR-2(-/-) mice compared to wild-type C57BL/6 animals. | 23668840 |
| Inflammation, Carcinoma, Squamous cell carcinoma, Squamous intraepithelial lesion, Cervical intraepithelial neoplasia grade 2, Cervical Intraepithelial Neoplasia | Altered Intercellular Communication | Cell smear findings suggested atypical squamous cells in 148 patients, low-grade squamous intraepithelial lesion in 62 patients, and high-grade squamous intraepithelial lesion in 107 patients, squamous cell carcinoma in 56 patients, and cervical biopsy-revealed inflammation in 89 patients, cervical intraepithelial neoplasia (CIN) I in 36 patients, CIN II in 43 patients, CIN III in 129 patients, and infiltrating carcinoma in 76 patients. | 23669440 |
| Inflammation, Communicable Diseases, Ductal Carcinoma, Cervical intraepithelial neoplasia grade 2, Cervical Intraepithelial Neoplasia | Altered Intercellular Communication | In the inflammation, CIN I, CIN II, CIN III, and infiltrating carcinoma groups, the infection rates of HR-HPV were 29.21%, 52.78%, 74.42%, 92.25%, and 93.42% (P < 0.01), respectively; the positive rates of hTERC gene amplification were 0.00%, 13.89%, 41.86%, 78.29%, and 89.47% (P < 0.01), respectively. | 23669440 |
| Inflammation, Cardiovascular Diseases | Altered Intercellular Communication | C-reactive protein (CRP) is a well-known biomarker of systemic inflammation and cardiovascular disease. | 23669654 |
| Inflammation, Lymphohistiocytosis, Hemophagocytic | Altered Intercellular Communication | Familial hemophagocytic lymphohistiocytosis (HLH) is a rare, life-threatening condition characterized by immune hyperactivation and clinical signs of extreme inflammation. | 23669735 |
| Inflammation, Superinfection | Altered Intercellular Communication | The critical feature is a skin barrier dysfunction that leads to epidermal inflammation and to bacterial superinfection. | 23670066 |
| Inflammation | Altered Intercellular Communication | Conjunctival inflammatory cell density and MG inflammation were increased in each group compared with those in controls (p < 0.001), with the highest values in SSI. | 23670123 |
| Inflammation, Hemorrhage, Gastrointestinal Pain, CTCAE, Pulmonary Embolism, Communicable Diseases, Diarrhea, Infection, Erythema, Peripheral edema, Deep thrombophlebitis | Altered Intercellular Communication | There were no significant differences in asymptomatic DVT, symptomatic DVT, symptomatic pulmonary embolism, or bleeding, but there were increases in other adverse events (including receipt of blood transfusion, erythema, peripheral edema, diarrhea, gastrointestinal or abdominal pain) and infections (including respiratory tract or lung infections, wound inflammation or infection, and extrasurgical-site infections), in patients with a BMI of 40 kg/m2 or greater compared with patients with a BMI less than 40 kg/m2. | 23670675 |
| Inflammation, Hemorrhage, Gastrointestinal Pain, CTCAE, Communicable Diseases, Diarrhea, Infection, Erythema, Postoperative Complications, Obesity, Peripheral edema, vinyltriethoxysilane | Altered Intercellular Communication | After THA or TKA, morbid obesity is not associated with an increased risk of VTE or bleeding but is associated with increased early postoperative complications, including erythema, peripheral edema, diarrhea and gastrointestinal or abdominal pain, wound inflammation or infection, extrasurgical-site infections, and respiratory tract or lung infections. | 23670675 |
| Inflammation, Cardiac complication, Diabetes Mellitus, Non-Insulin-Dependent | Altered Intercellular Communication | Understanding the interplay between adiposity, inflammation, and cardiovascular complications in type 2 diabetes mellitus (T2DM) remains a challenge. | 23670978 |
| Inflammation, Cardiac complication | Altered Intercellular Communication | However, further understanding the interplay between adiposity, plasma lipids, and inflammation may prove important in the prediction and management of cardiovascular complications in T2DM. | 23670978 |
| Presenile dementia, Inflammation, Depression, CTCAE | Altered Intercellular Communication | Many factors contribute to the etiology of depression and dementia, being inflammation one of those. | 23671023 |
| Inflammation, Inflammatory disorder, Coronary heart disease | Altered Intercellular Communication | The deletion variant allele of the NFKB1 - 94ins/delATTG promoter polymorphism leads to lower transcript levels of the p50 subunit, and the variant allele has been associated with the risk of several inflammatory diseases as well as coronary heart disease where inflammation is important in the pathogenesis. | 23671649 |
| Neurodegenerative Disorders, Inflammation | Altered Intercellular Communication | These changes are indicative of inflammation and may be involved in the prodromal processes leading to the development of neurodegenerative disease. | 23671673 |
| Inflammation, Urinary Calculi, Urolithiasis | Altered Intercellular Communication | We focused on alpha 1-antitrypsin (alpha1-AT), a protein verified to be present in urinary calculi, and which is considered as a protein of inflammation, comparing its presence in healthy subjects and patients with urolithiasis. | 23672078 |
| Communicable Diseases, Pneumonitis | Altered Intercellular Communication | The degrees of pulmonary inflammation and the number of organisms were much enhanced in T-bet-/- mice than in wild-type mice and T-bet tg/tg mice after MAC infection. | 23672176 |
| Kidney Failure, Chronic, Inflammation | Altered Intercellular Communication | Methylated arginines and nitric oxide in end-stage renal disease: impact of inflammation, oxidative stress and haemodialysis. | 23672496 |
| Kidney Failure, Chronic, Inflammation | Altered Intercellular Communication | To determine whether inflammation (C-reactive protein, CRP), oxidative stress (malondialdehyde, MDA) or haemodialysis (HD) affect associations between asymmetric (ADMA), symmetric (SDMA) dimethylarginine, NG-monomethyl-L-arginine (L-NMMA) and nitrite/nitrate (NOx) in end-stage renal disease (ESRD). | 23672496 |
| Kidney Failure, Chronic, HD Term Type, Inflammation | Altered Intercellular Communication | HD, oxidative stress or inflammation did not significantly affect the positive associations between methylated arginines and NOx in ESRD. | 23672496 |
| Refractory anemias, Inflammation, Observation Method - Coagulation | Altered Intercellular Communication | Within RA, coagulation factors were assessed alongside several demographic, inflammation and metabolic indicators. | 23673438 |
| Refractory anemias, Inflammation | Altered Intercellular Communication | Imbalance of coagulation and fibrinolytic mechanisms is common in RA and associates with age, inflammation, and metabolic factors. | 23673438 |
| Inflammation, physiopathological | Altered Intercellular Communication | Further studies may determine whether these abnormalities are the consequence of acute inflammation or markers of vascular dysfunction. | 23673438 |
| Inflammation, Gastric Stump | Altered Intercellular Communication | The endoscopic severity of remnant gastritis, as well as histological inflammation and activity, were higher in H. pylori-positive patients than in H. pylori-negative patients. | 23673508 |
| Burn injury | Altered Intercellular Communication | Normal abdominal expansion that occurs as a result of hormonal actions during pregnancy may be prevented by the presence of excessive scar tissue in individuals who have received severe burns. | 23673563 |
| Rheumatoid Arthritis, Inflammation, Cardiovascular Diseases | Altered Intercellular Communication | Rheumatoid arthritis and atypical cardiovascular disease: inflammation changing the clinical presentation. | 23673587 |
| Inflammation, Pulmonary Embolism, Thrombophilia, Cardiovascular Diseases | Altered Intercellular Communication | Although associated with adverse outcomes in other cardiovascular diseases, the prognostic value of an elevated white blood cell (WBC) count, a marker of inflammation and hypercoagulability, is uncertain in patients with pulmonary embolism (PE). | 23674436 |
| Chronic suppurative inflammation | Altered Intercellular Communication | Partial resection of the small intestine was performed, and pathological analysis suggested chronic suppurative inflammation in all layers of the ileal wall and mesentery. | 23674862 |
| Inflammation, Left ventricular diastolic dysfunction | Altered Intercellular Communication | Dissecting the mechanisms of left ventricular diastolic dysfunction and inflammation in peritoneal dialysis patients. | 23675418 |
| Inflammation | Altered Intercellular Communication | We hypothesized that adiposity might influence LV diastolic function through systemic inflammation in this specific group. | 23675418 |
| Diastolic dysfunction | Altered Intercellular Communication | Subjects with LV diastolic dysfunction had higher levels of the pro-inflammation cytokines and more visceral and peritoneal fat (all P<0.001) than control subjects. | 23675418 |
| Reduced FEV1/FVC ratio, Inflammation, Depression, CTCAE | Altered Intercellular Communication | Systemic inflammation, depression and obstructive pulmonary function: a population-based study. | 23676005 |
| ARCN1 gene, Inflammation, Chronic Obstructive Airway Disease, Depression, CTCAE, Chronic disease | Altered Intercellular Communication | Levels of Interleukin-6 (IL-6) and C-creative protein (CRP) indicating systemic inflammation are known to be elevated in chronic diseases including chronic obstructive pulmonary disease (COPD) and depression. | 23676005 |
| Cataract, Inflammation | Altered Intercellular Communication | [Post-operational acute inflammation of an eye in patients with cataracts]. | 23676483 |
| Inflammation, Endophthalmitis, CTCAE, Poisoning syndrome in animal | Altered Intercellular Communication | On the basis of obtained data is found that clinical symptomatology of autoimmune aseptic anterior uveitis, in particular, the eye inflammation associated with the broken syndrome of an eye anterior chamber-associated immune deviation (ACAID), considerably differs from clinical implications of acute endophthalmitis and a toxic syndrome of the anterior chamber of an eye. | 23676483 |
| Inflammation, Periodontal Diseases | Altered Intercellular Communication | Objective of our work: To carry out a comparative assessment of the expression level p53 protein and associate it with the degree of DNA damage in inflammation of periodontal disease. | 23676490 |
| Inflammation | Altered Intercellular Communication | It was established that acute inflammation in the periodontal tissues develop changes leading to DNA damage Acute inflammation is characterized by high levels of p53 Considerable damage to the nuclear DNA is called p53. | 23676490 |
| Abnormal inflammatory response | Altered Intercellular Communication | Topical steroids for chronic wounds displaying abnormal inflammation. | 23676816 |
| Inflammation, Hypertension, CTCAE, Atherosclerosis | Altered Intercellular Communication | Inflammation has a role in the pathogenesis of atherosclerosis, which causes hypertension. | 23676848 |
| Inflammation | Altered Intercellular Communication | The pharmacological action of metformin goes beyond mere glycemic control, decreasing markers of inflammation and contributing to the reduction of oxidative stress. | 23677182 |
| Inflammation, Electrocardiogram: myocardial infarction (finding) | Altered Intercellular Communication | The role of individual monocyte subsets in inflammation and recovery post-myocardial infarction (MI) is insufficiently understood. | 23677452 |
| Pain Distress Question, Swelling, Inflammation | Altered Intercellular Communication | Pain, inflammation or swelling of soft tissues orjoints is often treated with oral or topical formulation of lbuprofen. | 23678669 |
| Pain Distress Question, Swelling, Traumatic injury, Inflammation | Altered Intercellular Communication | A total of 170 patients suffering either from pain, inflammation or swelling of soft tissues or joints or having experienced a blunt trauma were enrolled into this study. | 23678669 |
| Inflammation, HIV Infections | Altered Intercellular Communication | The possible influence of CRT on the inflammation state related to chronic HIV infection was also examined. | 23678991 |
| Autoimmune Diseases, Inflammation, Primary malignant neoplasm | Altered Intercellular Communication | IL-10, a pleiotropic cytokine produced by macrophages, T-helper-2 cells, and B lymphocytes, is thought to play a potential pathogenetic or therapeutic role in a number of human conditions, such as inflammation, autoimmunity and cancer. | 23679256 |
| Dermatitis | Altered Intercellular Communication | flowers extract against skin inflammation: antioxidant, anti-inflammatory and matrix metalloproteinases inhibitory activities. | 23680157 |
| Inflammation, Carcinoma of lung | Altered Intercellular Communication | Associations between markers of inflammation and survival from lung cancer have been observed. | 23680692 |
| Inflammation, Hemorrhage, Sensorineural Hearing Loss (disorder) | Altered Intercellular Communication | Use of 3D-FLAIR MRI at 3 T may contribute to the elucidation of pathologic conditions in the inner ears of patients with ISSNHL and provide new radiologic indicators (mild hemorrhage, acute inflammation, presence or absence of BLB breakdown) that might assume the role of prognostic factors. | 23681028 |
| ARCN1 gene, Inflammation, Exacerbation | Altered Intercellular Communication | Our data suggest that FENO is a good surrogate marker of eosinophilic inflammation in COPD patients with exacerbations. | 23681903 |
| Myositis | Altered Intercellular Communication | Heightened muscle inflammation susceptibility may impair regenerative capacity in aging humans. | 23681911 |
| Myositis | Altered Intercellular Communication | We show for the first time that human aging is associated with muscle inflammation susceptibility (i.e., higher basal state of proinflammatory signaling) that is present in both tissue and isolated myogenic cells and likely contributes to the impaired regenerative capacity of skeletal muscle in the older population. | 23681911 |
| Inflammation, Cerebral white matter structure, Immune Reconstitution Inflammatory Syndrome, Meningitis, Cryptococcal | Altered Intercellular Communication | Cryptococcal meningitis accompanying lymphocytic inflammation predominantly in cerebral deep white matter: a possible manifestation of immune reconstitution inflammatory syndrome. | 23683170 |
| Inflammation, Cerebral white matter structure, Immune Reconstitution Inflammatory Syndrome, Meningitis, Cryptococcal | Altered Intercellular Communication | This is the first report of a case suggesting that cryptococcal meningitis can accompany lymphocytic inflammation predominantly in cerebral deep white matter as a possible manifestation of immune reconstitution inflammatory syndrome. | 23683170 |
| Inflammation, Prostatic Diseases, Benign prostatic hypertrophy | Altered Intercellular Communication | Effects of Serenoa repens, selenium and lycopene (Profluss(r)) on chronic inflammation associated with benign prostatic hyperplasia: results of "FLOG" (Flogosis and Profluss in Prostatic and Genital Disease), a multicentre Italian study. | 23683667 |
| Acute and chronic inflammation | Altered Intercellular Communication | To evaluate the efficacy of Profluss(r) on prostatic chronic inflammation (PCI). | 23683667 |
| Inflammation, Hypertension, CTCAE | Altered Intercellular Communication | The association of C-reactive protein, hypertension, and smoking with PWT is consistent with a role for inflammation or oxidative stress in determining treadmill walking performance. | 23684414 |
| Inflammation, Injury of bile duct | Altered Intercellular Communication | One theory regarding etiology is that bile duct injury is due to virus-induced autoreactive T cell-mediated inflammation. | 23685050 |
| Autoimmune Diseases, Inflammation | Altered Intercellular Communication | Regulatory T cell (Treg) abnormalities in BA could result in unchecked bystander inflammation and autoimmunity targeting bile ducts. | 23685050 |
| Inflammation, Anemia, Lupus Erythematosus, Systemic | Altered Intercellular Communication | As SLE is often associated with anaemia, we considered this factor in order to know whether RDW is related with inflammation, anaemia or both in SLE. | 23686089 |
| Inflammation, Anemia, Lupus Erythematosus, Systemic | Altered Intercellular Communication | Our results indicate that SLE patients show higher RDW irrespectively of anaemia status, and that RDW is influenced by both anaemia and inflammation, but the influence of anaemia is stronger. | 23686089 |
| Airway structure | Altered Intercellular Communication | "Extended" (multiple-flow) measurements of exhaled nitric oxide (FeNO) potentially can distinguish proximal and distal airway inflammation, but have not been evaluated previously in large populations. | 23687084 |
| Airway structure | Altered Intercellular Communication | J'awNO and conventional FeNO provide similar information, probably reflecting proximal airway inflammation. | 23687084 |
| Inflammation, Demyelination, Nerve Degeneration | Altered Intercellular Communication | Although inflammation appears to play a role in their formation, the mechanisms leading to demyelination and neurodegeneration are poorly understood. | 23687122 |
| Inflammation, Meningitis, Nerve Degeneration, Chronic purulent otitis media, B-Cell Lymphomas, Rasmussen subacute encephalitis, Tuberculosis, Meningeal, Chronic inflammatory disorder, MS gene | Altered Intercellular Communication | In our study, we showed that the combination of inflammation, plaque-like primary demyelination and neurodegeneration in the cortex is specific for multiple sclerosis and is not seen in other chronic inflammatory diseases mediated by CD8-positive T cells (Rasmussen's encephalitis), B cells (B cell lymphoma) or complex chronic inflammation (tuberculous meningitis, luetic meningitis or chronic purulent meningitis). | 23687122 |
| Inflammation, dupilumab | Altered Intercellular Communication | Dupilumab reduced biomarkers associated with Th2-driven inflammation. | 23688323 |
| Inflammation, Nasal Polyps, Chronic sinusitis | Altered Intercellular Communication | Chronic rhinosinusitis with nasal polyps (CRSwNP) is associated with TH2-dominant inflammation. | 23688414 |
| Inflammation | Altered Intercellular Communication | TSLP and its metabolic products might play an important role in the inflammation seen in patients with CRSwNP. | 23688414 |
| Tumor necrosis, Inflammation | Altered Intercellular Communication | A simple additive index of serum interleukin-6 and soluble tumor necrosis factor-a receptor-1 best captures the effect of chronic inflammation on mortality in older adults among the 15 biomarkers measured. | 23689826 |
| Inflammation, Carcinogenesis | Altered Intercellular Communication | Many studies suggest that inflammation and pro-inflammatory factors may play a role in the carcinogenesis with an involvement of the transcription factor NF-kappaB which activity can be controlled by various environmental factors, including many cytokines. | 23690221 |
| Metabolic Syndrome X, Cardiovascular system | Altered Intercellular Communication | We measured eight risk factors: the metabolic syndrome, its five components, insulin resistance and cardiovascular inflammation. | 23691005 |
| Inflammation, Complex Regional Pain Syndromes | Altered Intercellular Communication | Inflammation appears to play a role in CRPS as, for example, cytokines (like TNF-a) are involved in the affected limb. | 23692303 |
| Inflammation, Complex Regional Pain Syndromes | Altered Intercellular Communication | The ongoing inflammation is probably responsible for the central sensitization that sometimes occurs in CRPS. | 23692303 |
| Inflammation | Altered Intercellular Communication | Thus, early start of a TNF-a antagonist may counteract inflammation, thereby preventing rest damage and leading to recovery of the disease. | 23692303 |
| Inflammation, Granulation finding, Nonspecific interstitial pneumonia | Altered Intercellular Communication | The degree of inflammation and granulation tissue were milder in AEF than in UIP and NSIP and CLE showed milder inflammatory cells than AEF. | 23692421 |
| Inflammation, Claudication (finding) | Altered Intercellular Communication | Monitored daily ambulatory activity, inflammation, and oxidative stress in patients with claudication. | 23695338 |
| Inflammation, Peripheral Arterial Diseases | Altered Intercellular Communication | We determined the association between daily ambulatory activity and markers of inflammation and oxidative stress in patients with peripheral artery disease (PAD) and claudication. | 23695338 |
| Inflammation, MS gene, Trauma, Nervous System | Altered Intercellular Communication | Normal-appearing white matter and GM, despite seeming normal in conventional magnetic resonance imaging (MRI), are important loci of widespread inflammation, neuronal damage, and source of progressive disability in multiple sclerosis (MS). | 23695433 |
| Granulomatous inflammation, Non-necrotizing granulomatous inflammation | Altered Intercellular Communication | The histological examination of a turbinectomy revealed a granulomatous inflammation with non-caseating granulomas. | 23695850 |
| Inflammation, Uveitis | Altered Intercellular Communication | One of her main symptoms was significant uveitis with a pronounced inflammation in the anterior chamber. | 23695850 |
| ARCN1 gene, Inflammation, Chronic Obstructive Airway Disease | Altered Intercellular Communication | Systemic inflammation and oxidative stress are the most important features of chronic obstructive pulmonary disease (COPD). | 23697277 |
| ARCN1 gene | Altered Intercellular Communication | The presence of oxidative stress in the airways of smokers, the largest population of COPD patients, is a consequence of direct inhalation of cigarette smoke and increased inflammation-related production of reactive oxygen species. | 23697277 |
| Inflammation | Altered Intercellular Communication | On the other hand, oxidative stress appears to be the key component of many processes associated with chronic inflammation. | 23697277 |
| ARCN1 gene | Altered Intercellular Communication | We showed an increase of serum CRP and GGT values in COPD patients, and we suggest that serum GGT activity might also represent an inflammation/oxidative stress marker. | 23697277 |
| Inflammation, Uveitis | Altered Intercellular Communication | Postsurgical uveitis was defined as persistent inflammation for >= 6 months after surgery. | 23697858 |
| Inflammation, Lung diseases | Altered Intercellular Communication | Glucose transporter-1 distribution in fibrotic lung disease: association with [18F]-2-fluoro-2-deoxyglucose-PET scan uptake, inflammation, and neovascularization. | 23699745 |
| Inflammation, Fibrosis Assessment | Altered Intercellular Communication | Thus, FDG-PET scan may detect inflammation and neovascularization in lung fibrosis. | 23699745 |
| Chronic sinusitis | Altered Intercellular Communication | Chronic rhinosinusitis is a common inflammatory condition in western countries. | 23700266 |
| Anorexia | Altered Intercellular Communication | Whether the association between dietary protein intake and survival is causal or a consequence of anorexia secondary to protein-energy-wasting/inflammation or other factors should be explored in interventional trials. | 23700345 |
| Inflammation | Altered Intercellular Communication | The main incriminated mechanisms are the iron deficiency and the chronic inflammation. | 23700874 |
| Inflammation, Anemia | Altered Intercellular Communication | The main cause identified was mixed type anemia, followed by iron deficiency and inflammation. | 23700874 |
| methyldopa, Inflammation, Retina, Lesion of retina | Altered Intercellular Communication | This study shows the role of oxidative stress and inflammation in retinal structural lesions in AMD and the importance of blood markers in early detection of oxidative stress and thus of retinal lesions in this disease. | 23700902 |
| Inflammation, Cerebrovascular accident | Altered Intercellular Communication | Inflammation and activation of the neuroendocrine systems comprise important aspects of stroke pathophysiology. | 23701638 |
| Inflammation, Fracture, Osteoporosis | Altered Intercellular Communication | It has been suggested that inflammation may have a role in osteoporosis and subsequent fracture risk. | 23702388 |
| Inflammation, Malignant neoplasm of endometrium | Altered Intercellular Communication | Chronic inflammation may be important in endometrial cancer etiology. | 23702681 |
| Epithelial Damage, Inflammation | Altered Intercellular Communication | Biopsies were evaluated for specific changes in the following general categories: acute inflammation, chronic inflammation, epithelial damage, and architectural distortion. | 23702713 |
| Inflammation, Blood Clot, Fracture | Altered Intercellular Communication | The pathologic changes are those of organizing thrombus with and without inflammation with minor complications of foot and strut fracture. | 23703961 |
| Pruritus, Purpura, Orbital Pseudotumor, Subconjunctival hemorrhage | Altered Intercellular Communication | A middle aged female patient presented with generalised palpable purpura associated with intense pruritus along with subconjunctival haemorrhage and orbital inflammation. | 23704433 |
| palladium, Inflammation, Hemorrhage, Dental Plaque | Altered Intercellular Communication | Gingival inflammation (simplified gingival index, GI-S), plaque levels (plaque control record index, PCR), bleeding on probing (BOP) and probing depth (PD), were recorded for all participants before and after IVF. | 23705534 |
| Chronic lymphocytic inflammation, Pontine structure, Clippers | Altered Intercellular Communication | Chronic lymphocytic inflammation with pontine perivascular enhancement responsive to steroids (CLIPPERS) was first described in 2010 by Pittock and colleagues. | 23706003 |
| Inflammation, Amyloidosis | Altered Intercellular Communication | This suggests that chronic stimulation and inflammation of the skin lining the external auditory canal induced amyloidosis. | 23706305 |
| Communicable Diseases | Altered Intercellular Communication | These outcome differences in postpubertal children may reflect a hormonal influence on the response to infection or differences in underlying comorbidities, source of infection, or behavior. | 23706357 |
| Takayasu Arteritis | Altered Intercellular Communication | Takayasu arteritis is a rare, chronic idiopathic, occlusive inflammation of the aorta and its major branches. | 23709154 |
| Inflammation | Altered Intercellular Communication | Precancerous conditions which included polyps and non-specific bowel inflammations were observed in 491 and 52 patients, respectively. | 23709378 |
| Inflammation, Cardiovascular Diseases | Altered Intercellular Communication | HIV-infected patients are at increased risk for cardiovascular disease, which may be mediated in part by inflammation. | 23709436 |
| Hormone abnormality, Hypopituitarism | Altered Intercellular Communication | A detailed clinical history and a careful physical examination in children presenting with multiple clinical signs of hypopituitarism may lead to a timely diagnosis, avoiding clinical morbidity associated to untreated hormonal abnormalities. | 23709551 |
| Inflammation | Altered Intercellular Communication | The long-term ventilation and drainage disorder and recurrent inflammation attack may play an important role in occurrence, development and prognosis of MD. | 23710863 |
| Nasal inflammation, MS4A2 wt Allele | Altered Intercellular Communication | In addition, persistent nasal inflammation appears to increase the risk of BHR only in the presence of atopy. | 23710946 |
| Inflammation, Heart failure | Altered Intercellular Communication | Red cell distribution width is associated with physical inactivity and heart failure, independent of established risk factors, inflammation or iron metabolism; the EPIC-Norfolk study. | 23711445 |
| Inflammation, Fibrosis Assessment | Altered Intercellular Communication | Single nucleotide polymorphisms (SNPs) of EPHX2 alter sEH activity and are associated with increased [rs41507953 (K55R)] or reduced [rs751141 (R287Q)] cardiovascular risk via modulation of fibrosis, inflammation or cardiac ion channels. | 23711456 |
| Inflammation, HIV Infections, Atherosclerosis | Altered Intercellular Communication | Our findings suggest that HIV infection impairs endothelial function and predisposes to atherosclerosis through chronic inflammation and subsequent accumulation of ADMA. | 23711612 |
| Inflammation, Ventricular hypertrophy | Altered Intercellular Communication | Low grade inflammation and ECG left ventricular hypertrophy in urban African males: The SABPA study. | 23711691 |
| Hypernatremia, Inflammation, Left Ventricular Hypertrophy | Altered Intercellular Communication | Therefore, a novel investigation aimed to assess whether inflammation and pressure overload would have an additive association with ECG left ventricular hypertrophy (LVH). | 23711691 |
| Inflammation, Congenital Abnormality | Altered Intercellular Communication | Hyperdynamic blood pressure and inflammation acted in tandem as possible promoting factors to structural wall abnormalities in African men. | 23711691 |
| Inflammation, Nasal Polyps | Altered Intercellular Communication | Total and antigen- (fungi, mites and staphylococcal enterotoxins) specific IgEs in nasal polyps is related to local eosinophilic inflammation. | 23711866 |
| Inflammation, Nasal Polyps | Altered Intercellular Communication | Total and specific immunoglobulin E (IgE) in nasal polyps (NP) is related to local eosinophilic inflammation. | 23711866 |
| Inflammation | Altered Intercellular Communication | Local total IgE and antigen (fungi, mites and SEs)-specific IgEs in NP are related to the local eosinophilic inflammation of AFRS and CRSwNP. | 23711866 |
| TNF protein, human, Inflammation, Diabetes Mellitus, Non-Insulin-Dependent | Altered Intercellular Communication | This occurred despite high levels of B cell-intrinsic inflammation (TNF-a) in T2D patients, which was surprising as we had previously demonstrated this negatively impacts B cell function. | 23711934 |
| UBC protein, human, Inflammation, Malignant neoplasm of urinary bladder, Carcinoma of bladder | Altered Intercellular Communication | Here, we demonstrate that with the increased sensitivity of modern FTIR spectrometers, automatisation of sample preparation and modern bioinformatics, it is possible to identify and validate spectral biomarker candidates for distinguishing between urinary bladder cancer (UBC) and inflammation in suspected bladder cancer patients. | 23712384 |
| Inflammation, Swelling | Altered Intercellular Communication | Included cases presented with recurrent inflammation and swelling of a single major salivary gland, without identifiable etiology on examination and imaging. | 23712592 |
| Inflammation, Weight decreased | Altered Intercellular Communication | Clinicians concerned about inflammation and cardiovascular risk should recommend weight loss diets most likely to succeed for their patients. | 23712970 |
| Inflammation | Altered Intercellular Communication | There was evidence of inflammation in his right calcaneus and toe walking was noted. | 23713331 |
| Inflammation, Diplopia, Extraocular, Cysticercosis, Exophthalmos | Altered Intercellular Communication | Orbital cysticercosis commonly presents with signs of inflammation, diplopia, restricted extraocular motility and proptosis. | 23713340 |
| Orchitis, Tenosynovitis | Altered Intercellular Communication | When individual components of the PsAMRIS were evaluated, intra- and inter-reader agreement was poor to moderate, especially for tenosynovitis and periarticular inflammation. | 23713482 |
| Degenerative polyarthritis, Inflammation, Arthritis, Collagen Diseases | Altered Intercellular Communication | Patients were familiar with many of the terms such as arthritis, osteoarthritis, rheumatism, inflammation, etc. | 23713971 |
| Inflammation, Periodontal Route of Administration | Altered Intercellular Communication | Vegetarians revealed better periodontal conditions (less inflammation signs, less periodontal damage and a better dental home care). | 23714722 |
| Inflammation, Postoperative Complications | Altered Intercellular Communication | The most common postoperative complication was infection/inflammation (n = 12). | 23714988 |
| polyps, Inflammatory disease of mucous membrane | Altered Intercellular Communication | Systemic steroid treatment is effective not only in decreasing polyp size but also in controlling mucosal inflammation. | 23715001 |
| Inflammatory abnormality of the eye, Corneal dystrophy, Corneal Diseases | Altered Intercellular Communication | Corneal dystrophy is defined as bilateral and symmetric primary corneal disease, without previous associated ocular inflammation. | 23715139 |
| Granulomatous inflammation, Syndrome | Altered Intercellular Communication | Cord colitis syndrome: a cause of granulomatous inflammation in the upper and lower gastrointestinal tract. | 23715165 |
| Chronicity, Granulomatous inflammation | Altered Intercellular Communication | CCS exhibits a peculiar histopathologic appearance, as it commonly manifests as granulomatous inflammation involving the upper and lower gastrointestinal tract, with features of chronicity in the colon. | 23715165 |
| Inflammation | Altered Intercellular Communication | Endoscopic biopsies of the stomach and colon revealed granulomatous inflammation, consisting of scattered ill-defined aggregates of epithelioid histiocytes, with associated mild neutrophilic inflammation and mildly increased epithelial cell apoptosis. | 23715165 |
| Granulomatous inflammation, Epithelial | Altered Intercellular Communication | In the colon, the granulomatous inflammation was associated with surface epithelial injury (including surface erosions) and contained occasional multinucleated epithelioid giant cells. | 23715165 |
| Inflammation, Neutrophilic urticaria | Altered Intercellular Communication | Neutrophilic urticaria with systemic inflammation: a case series. | 23715523 |
| Inflammation, Urticaria, Connective Tissue Diseases, Malignant Neoplasms | Altered Intercellular Communication | We describe 2 patients having neutrophilic urticaria with systemic inflammation (NUSI) without known connective tissue disorder or malignancy. | 23715523 |
| Inflammatory, Inflammation | Altered Intercellular Communication | We therefore sought to model the relationship between systemic inflammatory illness and lipid levels using C-reactive protein (CRP) as the prototypical marker of inflammation. | 23716069 |
| Edema, Cardiac, Myocardial | Altered Intercellular Communication | Myocardial oedema on CMR is a characteristic feature of acute TT-CMP, which reflects acute inflammation and acute myocardial injury. | 23716287 |
| Inflammation, Hypertension, CTCAE | Altered Intercellular Communication | However, the existence of T-cell-driven inflammation in human hypertension has not been confirmed. | 23716586 |
| Inflammation, Hypertension, CTCAE | Altered Intercellular Communication | Immunosenescent CD8(+) T cells and C-X-C chemokine receptor type 3 chemokines are increased in human hypertension, suggesting a role for T-cell-driven inflammation in hypertension. | 23716586 |
| Presenile dementia | Altered Intercellular Communication | Since GQ1ba is present in the cerebral cortex and hippocampus, the presence of anti-GQ1ba antibodies may play an important role in disrupting cholinergic synaptic transmission and may participate in the pathogenesis of dementia. | 23717411 |
| Inflammation, Hypoalbuminemia | Altered Intercellular Communication | However, the relationship between peritoneal inflammation, peritoneal transport properties and hypoalbuminaemia has not been fully elucidated. | 23718260 |
| Inflammation, Hypoalbuminemia | Altered Intercellular Communication | Hypoalbuminaemia was attributable to both the increased peritoneal permeability and systemic inflammation, and intraperitoneal inflammation might contribute to developing these complications. | 23718260 |
| Inflammation | Altered Intercellular Communication | Endoscopy revealed severe inflammation and ulcerations of the entire colon. | 23720057 |
| Facioscapulohumeral muscular dystrophy 1a, Muscular Dystrophy, Facioscapulohumeral, Autosome | Altered Intercellular Communication | Magnetic resonance imaging of muscle shows short tau-inversion recovery (STIR) brightness in autosomal dominant facioscapulohumeral muscular dystrophy (FSHD1) suggestive of active inflammation/injury. | 23720194 |
| Inflammation, Saint Lucia, Colitis | Altered Intercellular Communication | a layer of subepithelial collagen band >= 10 mm in collagenous colitis (CC) with concomitant inflammation and at least 20 lymphocytes per 100 epithelial cells in lymphocytic colitis (LC). | 23721118 |
| Tubulitis Assessment, Viremia, Interstitial inflammation | Altered Intercellular Communication | The tubulitis score, extent of tubules with intraepithelial lymphocytes, and interstitial inflammation significantly increased from the time of increasing to decreasing viremia. | 23721552 |
| Inflammation, Postoperative infection, Malignant neoplasm of gastrointestinal tract | Altered Intercellular Communication | Correlation between preoperative systemic inflammation and postoperative infection in patients with gastrointestinal cancer: a multicenter study. | 23722282 |
| Inflammation, Postoperative infection, Malignant neoplasm of gastrointestinal tract | Altered Intercellular Communication | Our aim was to examine the association between postoperative infection and preoperative systemic inflammation in patients undergoing resection of gastrointestinal cancer. | 23722282 |
| Inflammation, Postoperative infection, Malignant neoplasm of gastrointestinal tract | Altered Intercellular Communication | Preoperative systemic inflammation is associated with postoperative infection in patients undergoing resection of gastrointestinal cancer. | 23722282 |
| malignant disease, Inflammation | Altered Intercellular Communication | It is well-known that the plasma level of group IIA phospholipase A2 (sPLA2-IIA) is increased in patients with malignant diseases, but whether the up-regulated enzyme expression is directly related to tumorigenesis or a consequence of tumor-associated inflammation remains unresolved. | 23722320 |
| Inflammation, Neurogenic Inflammation | Altered Intercellular Communication | Molecular imaging of neuroinflammation can be instrumental in the management of NORSE by guiding placement of intracranial electrodes or assessing the extent and severity of inflammation for antiinflammatory interventions. | 23724839 |
| Renal Insufficiency, Inflammation, Metabolic Syndrome X, ETV3 wt Allele | Altered Intercellular Communication | Previous studies have shown that either metabolic syndrome (MetS) or chronic inflammation is related to renal impairment. | 23725496 |
| Proteinuria, Inflammation, Damage | Altered Intercellular Communication | Proteinuria (P) is a early sign of inflammation and renal damage. | 23726637 |
| Communicable Diseases, Virus Diseases, Myositis, CTCAE 5.0, Myositis | Altered Intercellular Communication | Although no infectious etiology was found, it seems that this semiological entity is a form of benign acute myositis (BAM), a benign muscular inflammation, arising from viral infection and occurring in school-age children, more frequently in males, between 6 and 12 years of age. | 23726681 |
| Multiple Organ Failure, Inflammation | Altered Intercellular Communication | Heatstroke (HS) is a life-threatening condition, manifested by systemic inflammation and multiorgan failure. | 23726745 |
| Dental Plaque | Altered Intercellular Communication | The plaque formation/morphology may depend on local environment and is independent of oxidative stress/inflammation observed on the level of the whole body. | 23726810 |
| TNF protein, human, Inflammation, Colorectal Carcinoma | Altered Intercellular Communication | We compared systemic inflammatory profiles in CRC (n=99), health (n=98), high CRC-risk conditions (n=48) and overt inflammation (n=69) by multiplexed analysis of IL-1b, IL-6, IL-8, FGF-2, G-CSF, GM-CSF, MCP-1, MIP-1a, TNF-a, VEGF-A, and PDGF-B and CEA. | 23726839 |
| Fibrosis Assessment, Non-alcoholic Fatty Liver Disease, Diabetes Mellitus, Non-Insulin-Dependent, Hepatitis | Altered Intercellular Communication | In this phase 2 trial, administration of 25 or 50 mg OCA for 6 weeks was well tolerated, increased insulin sensitivity, and reduced markers of liver inflammation and fibrosis in patients with type 2 diabetes mellitus and nonalcoholic fatty liver disease. | 23727264 |
| Inflammation, Primary malignant neoplasm, Pathology, Diabetes Mellitus, Heart Diseases | Altered Intercellular Communication | This range of pathologies include general signs of premature aging, neuro-muscular dysfunctions, cancer, diabetes, various heart diseases, inflammation and other conditions not previously known to be related to mitochondrial function. | 23727386 |
| Inflammation, Disease | Altered Intercellular Communication | Analysis of the most increased (>=1.5 fold) and decreased (<=0.8 fold) proteins in the keratoconus corneal epithelial protein extracts identified proteins related to dermal diseases, inflammation, epithelial stratification and mesenchymal changes. | 23727491 |
| Communicable Diseases, Weight decreased, Pneumonitis | Altered Intercellular Communication | After infection with diverse strains of H1N1 influenza, treated mice showed minimal weight loss and lung inflammation. | 23728362 |
| Intraocular inflammation, Endophthalmitis, CTCAE | Altered Intercellular Communication | Endogenous endophthalmitis is a sight-threatening condition caused by microorganisms crossing the blood-ocular barrier and inducing profound intraocular inflammation. | 23728762 |
| Thyroid carcinoma | Altered Intercellular Communication | High serum thyroid-stimulating hormone (TSH) is associated with thyroid carcinoma in patients with thyroid nodules. | 23728859 |
| Diabetes Mellitus, Insulin-Dependent, Inflammation, Cardiomyopathies, Monogenic autoinflammatory syndrome | Altered Intercellular Communication | Pigmentary hypertrichosis and non-autoimmune insulin-dependent diabetes mellitus (PHID) syndrome is associated with severe chronic inflammation and cardiomyopathy, and represents a new monogenic autoinflammatory syndrome. | 23729543 |
| Inflammation, Cardiomyopathies | Altered Intercellular Communication | We report a new association of PHID syndrome with severe systemic inflammation, scleroderma-like changes, and cardiomyopathy. | 23729543 |
| Inflammation, Liver Dysfunction | Altered Intercellular Communication | Laboratory data showed mild inflammation and no liver or renal dysfunction. | 23729712 |
| Inflammation, Damage | Altered Intercellular Communication | At the same level of inflammation, the prognosis regarding joint damage is believed to be different for anticitrullinated protein antibody (ACPA)-negative and ACPA-positive patients. | 23729803 |
| Inflammation, Damage | Altered Intercellular Communication | At the same level of inflammation, ACPA-negative patients have less joint damage and lower probability for damage in newly affected joints than ACPA-positive patients. | 23729803 |
| Inflammation, Arthritis, Polyarthritis | Altered Intercellular Communication | To compare Doppler ultrasound (US) and 3.0-Tesla magnetic resonance imaging (3.0-T MRI) findings of synovial inflammation in the tendons and joints in an early polyarthritis cohort (patients who presented < 1 year after arthritis onset) using a bilateral hand and wrist evaluation. | 23729806 |
| Inflammatory abnormality of the eye | Altered Intercellular Communication | Decreased levels of tear IL-10, an anti-inflammatory cytokine, may lead to an inflammatory ocular surface environment, exacerbate ocular surface inflammation, and deteriorate tear function tests. | 23730902 |
| Rosacea, Inflammatory abnormality of the eye | Altered Intercellular Communication | A bigger sample size, including rosacea patients with corneal involvement, is needed to confirm the role of cytokines in the pathogenesis of rosacea-associated ocular inflammation. | 23730902 |
| Inflammation, Colonization, Acne | Altered Intercellular Communication | Inflammation, increased sebum production and P. acnes colonization are key factors in acne pathogenesis. | 23731195 |
| Inflammation, Ichthyosis Bullosa of Siemens | Altered Intercellular Communication | It has been suggested that these symptoms are a reflection of occult inflammation rather than coexisting IBS. | 23731196 |
| Inflammation, Coronary Artery Vasospasm, Cardiac Arrhythmia | Altered Intercellular Communication | Intravenous nicorandil infusion dilates the coronary artery and reduces inflammation, coronary spasm, and arrhythmia. | 23731922 |
| Inflammation | Altered Intercellular Communication | Inflammation is thought to play a key role in many patients, characteristically with an increase in mast cells within the detrusor muscle of the bladder. | 23732167 |
| Inflammation | Altered Intercellular Communication | The IgG4-positive patients were of older age and had increased severe inflammation and decreased bladder capacity as compared with the IgG4-negative patients. | 23732167 |
| Barrett Esophagus, Inflammation, Esophagitis | Altered Intercellular Communication | At endoscopy 83% had evidence of chronic inflammation in the distal esophagus on histopathology, including 22% with moderate to severe esophagitis and 7% with Barrett's esophagus. | 23732271 |
| Inflammation, Illness (finding) | Altered Intercellular Communication | Because severe inflammation in adults increases CNP, we studied CNP peptides and inflammatory markers in children with acute illness. | 23732776 |
| Inflammation, Cardiotoxicity, Cardiovascular Diseases | Altered Intercellular Communication | These findings are important because MHC-Cre mice are widely used in cardiovascular research despite the limitations imposed by Cre-induced cardiac toxicity, and also because inflammation is an important pathological component of many human cardiovascular diseases. | 23732814 |
| Inflammation, Cardiac complication, Kidney Diseases, Diabetes Mellitus | Altered Intercellular Communication | Studies in recent years suggest a role for inflammation, proinflammatory cytokines in particular, the development of microvascular complications of diabetes, including nephropathy. | 23734508 |
| Airway structure | Altered Intercellular Communication | Relationship between airway pathophysiology and airway inflammation in older asthmatics. | 23734667 |
| Airway structure | Altered Intercellular Communication | Airway closure is also greater in older asthmatics, an observation that may be explained by differences in airway inflammation. | 23734667 |
| Airway structure, AHR wt Allele, Eosinophilic inflammation, Asthma, Respiratory Hypersensitivity | Altered Intercellular Communication | We hypothesized that in older adult patients with asthma, neutrophil airway inflammation increases airway closure during bronchoconstriction, while eosinophil airway inflammation increases airway hyperresponsiveness (AHR). | 23734667 |
| Airway structure | Altered Intercellular Communication | Airway inflammation was assessed by induced sputum and exhaled nitric oxide (eNO). | 23734667 |
| Airway structure, Inflammation | Altered Intercellular Communication | Eosinophilic airway inflammation is associated with AHR while neutrophilic inflammation may be an important determinant of airflow limitation at rest and airway closure during bronchoconstriction. | 23734667 |
| Inflammation, Ulcerative Colitis | Altered Intercellular Communication | To evaluate the efficacy of mesalazine suppositories in patients with ulcerative colitis (UC) and rectal inflammation; and in patient groups categorised by the extent of lesions. | 23734840 |
| Inflammation, Ulcerative Colitis | Altered Intercellular Communication | Mild-to-moderate UC patients with rectal inflammation were randomly assigned either a 1 g mesalazine or placebo suppository. | 23734840 |
| Inflammation, Granulomatous, Necrosis | Altered Intercellular Communication | A biopsy of the left temporal lesion showed a granulomatous and angiodestructive inflammation with infiltration of many CD4(+) T-lymphocytes and multinucleated giant cells and with fibrinoid necrosis of the arterial walls in the subarachnoid space. | 23735532 |
| Carotid Endarterectomy, Inflammation, Impaired cognition | Altered Intercellular Communication | Inflammation and cognitive dysfunction in type 2 diabetic carotid endarterectomy patients. | 23735728 |
| Cerebrovascular Disorders, Inflammation, Impaired cognition, diabetic | Altered Intercellular Communication | Type 2 diabetic patients have a high incidence of cerebrovascular disease, elevated inflammation, and high risk of developing cognitive dysfunction following carotid endarterectomy (CEA). | 23735728 |
| Inflammation, Impaired cognition, Diabetes Mellitus, Non-Insulin-Dependent | Altered Intercellular Communication | To elucidate the relationship between inflammation and the risk of cognitive dysfunction in type 2 diabetic patients, we aim to determine whether elevated levels of systemic inflammatory markers are associated with cognitive dysfunction 1 day after CEA. | 23735728 |
| Acanthosis Nigricans, Inflammation, Obesity | Altered Intercellular Communication | MSC-N showed strong positive genetic correlations with obesity, insulin resistance, inflammation, and acanthosis nigricans, and negative genetic correlation with physical fitness. | 23736306 |
| Communicable Diseases, Inflammation, Pathology | Altered Intercellular Communication | Inclusion criteria for the patients were presence of at least 2 mm of bone beyond the root apex, the absence of acute signs of infection or inflammation in the treatment area, and the absence of systemic pathologies that would contraindicate bone healing around implants. | 23736310 |
| Inflammation, Cardiac complication, Obesity | Altered Intercellular Communication | Childhood obesity is accompanied by low-grade systemic inflammation, which contributes to the development of insulin resistance and cardiovascular complications later in life. | 23736361 |
| Inflammation, Obesity | Altered Intercellular Communication | 25(OH)D deficiency in childhood obesity was associated with enhanced systemic inflammation and reduced insulin sensitivity. | 23736361 |
| Inflammation, Disease, Orbital Neoplasms | Altered Intercellular Communication | Swelling of the upper eyelid in childhood is caused by a variety of diseases and is very often generated by inflammation but orbital tumors should always be considered in the differential diagnostics. | 23736662 |
| Inflammation | Altered Intercellular Communication | Cholecystectomy can become hazardous when inflammation develops, leading to anatomical changes in Calot's triangle. | 23736889 |
| Inflammation | Altered Intercellular Communication | The operations were performed laparoscopically irrespective of the grade of inflammation estimated preoperatively. | 23736889 |
| Inflammation | Altered Intercellular Communication | However, patients with severe inflammation of the gallbladder underwent LSC involving resection of the anterior wall of the gallbladder, removal of all stones and placement of an infrahepatic drainage tube. | 23736889 |
| Inflammation, Adduction | Altered Intercellular Communication | The resulting increase in adduction moment suggests greater medial compartment loads, which may combine with elevated levels of inflammation to contribute to the increased risk of medial OA in this population. | 23737249 |
| Infarction, Inflammation, Demyelination, Traumatic injury | Altered Intercellular Communication | Typical causes of internuclear ophthalmoplegia (INO) include arterial infarcts, demyelinating conditions, inflammation and trauma. | 23737577 |
| Proctitis | Altered Intercellular Communication | Inflammation mediators related to radiation proctitis are partially elucidated, and neovascularization is thought to play a key role. | 23737650 |
| Tissue injury | Altered Intercellular Communication | Our results showed that in postradiation rectal biopsy specimens neoangiogenesis seems to be inflammation-related and constitutes a significant postradiation component of the tissue injury. | 23737650 |
| Osteomyelitis, Inflammation | Altered Intercellular Communication | In this article, we report the case of acute pneumococcal osteomyelitis of the humerus in an immunocompetent and otherwise healthy 44-year-old male patient presenting with minor inflammation signs and misleading clinical features. | 23738890 |
| Pain Distress Question | Altered Intercellular Communication | Inflammation of lumbar bursae may be responsible for the low back pain reported by patients with PMR. | 23739147 |
| Inflammation, Endothelial dysfunction | Altered Intercellular Communication | Angiopoietin-like protein 2 (Angptl2) is an adipokine that promotes inflammation and endothelial dysfunction of the vessels. | 23739531 |
| Inflammation, Failure, Choroidal and Ciliary Body Melanoma pT1d TNM Finding v8 | Altered Intercellular Communication | BBDR plasma cytokine levels mirrored the signatures showing early inflammation, followed by induction of a regulated state that correlated with failure of virus to induce T1D in older rats. | 23739610 |
| hearing impairment, Inflammation | Altered Intercellular Communication | Long-term assessment of systemic inflammation and the cumulative incidence of age-related hearing impairment in the epidemiology of hearing loss study. | 23739996 |
| hearing impairment, Inflammation, Disease | Altered Intercellular Communication | Although research has linked systemic inflammation to various diseases of aging, few studies have examined the potential role it may play in the development of age-related hearing impairment. | 23739996 |
| Pain Distress Question, Inflammation, Dyssomnias | Altered Intercellular Communication | Sleep disturbance and pain were found to be most important, although inflammation, as measured by CRP, was also associated. | 23740186 |
| Inflammation, Spondylitis | Altered Intercellular Communication | Evidence that autophagy, but not the unfolded protein response, regulates the expression of IL-23 in the gut of patients with ankylosing spondylitis and subclinical gut inflammation. | 23740229 |
| Acute and chronic inflammation | Altered Intercellular Communication | Autophagy but not UPR was required to modulate the expression of IL-23 in isolated LPMCs of AS patients with chronic gut inflammation, CD patients and controls. | 23740229 |
| Inflammation, Arthritis | Altered Intercellular Communication | The impact of inflammation on metabolomic profiles in patients with arthritis. | 23740368 |
| Inflammation, Arthritis | Altered Intercellular Communication | In early arthritis, we were able to stratify the patients according to the level of current inflammation, with C-reactive protein correlating with metabolic differences in 2 separate groups (P < 0.001). | 23740368 |
| Loss, Inflammation | Altered Intercellular Communication | Biopsy of a lumbar dorsal sensory root showed myelinated fiber degeneration and loss, with endoneurial inflammation. | 23740462 |
| Inflammation | Altered Intercellular Communication | CTLA-4Ig treatment significantly reduces glandular inflammation in primary SS, induces several cellular changes, and increases saliva production. | 23740889 |
| Ischemia, Dryness (characteristic), Inflammation | Altered Intercellular Communication | Wavelet augmented ultrasound is sensitive to the organisational elements of choroidal microarchitecture relating to scatter and fluid tissue boundaries such as seen in ischaemia and inflammation, allowing statistically significant differentiation of dry, wet and non-AMD eyes. | 23740965 |
| ARCN1 gene, Inflammation | Altered Intercellular Communication | In addition, patients with mixed granulocytic or neutrophilic stable COPD remained at lower lung functions and higher levels of inflammation. | 23741289 |
| Inflammation | Altered Intercellular Communication | Patients with AECOPD display heterogeneous inflammation, and the profiles of sputum inflammatory cells may be used as valuable biomarkers for the classification of AECOPD patients. | 23741289 |
| Inflammation | Altered Intercellular Communication | Detection of subclinical synovial inflammation by microwave radiometry. | 23741349 |
| Refractory anemias, Inflammation, Degenerative polyarthritis | Altered Intercellular Communication | Of 40 RA and 20 osteoarthritis knees examined, ultrasound findings indicative of subclinical inflammation (fluid effusion and/or Doppler signal) were found in 24 and 12, respectively, in which the temperature was higher than healthy knees and DT was lower (-0.9+-0.7 in RA and -1.0+-0.5 in osteoarthritis versus -1.8+-0.2degC, p<0.001). | 23741349 |
| Refractory anemias, Inflammation, Degenerative polyarthritis | Altered Intercellular Communication | The 5 RA knees with power Doppler findings indicative of grade 2 inflammation had a DT 3 times lower compared to healthy (-0.6+-0.6, p = 0.007), whereas the 9 RA and the 7 osteoarthritis knees with additionally fluid effusion, had even lower DT (-0.4+-0.7, p<0.001). | 23741349 |
| Arthritis | Altered Intercellular Communication | Using a safe, rapid and easy-to-perform method, such as microwave radiometry, thermal changes within the knee joint may reflect non-clinically apparent joint inflammation. | 23741349 |
| Inflammation, Leprosy, Paucibacillary, Hypertrophy | Altered Intercellular Communication | Slow progression of disease, the lack of neural enlargement and the neural biopsies without inflammation suggest that most of these patients could have spontaneously cured PNL, as happens with other cases of paucibacillary leprosy. | 23741881 |
| Pulmonary Emphysema, Pneumonitis | Altered Intercellular Communication | By neutralizing CXCL13 in a mouse model of chronic cigarette smoke (CS) exposure, we aimed at interrogating the link between lymphoid follicles and development of pulmonary inflammation, emphysema, and airway wall remodeling. | 23742729 |
| Inflammation, Destruction (action) | Altered Intercellular Communication | Neutralization of CXCL13 partially protects mice against CS-induced inflammation in bronchoalveolar lavage and alveolar wall destruction. | 23742729 |
| Inflammation, Fever, CTCAE | Altered Intercellular Communication | Fever is an important sign of inflammation recognized by health care practitioners and family caregivers. | 23742739 |
| Inflammation | Altered Intercellular Communication | Deficient production of immunomodulatory PGs may promote chronic inflammation and airway remodeling. | 23742951 |
| vascular inflammations | Altered Intercellular Communication | The strong negative association between exercise and Lp-PLA2 activity and the fact that the latter resulted to be the unique continuous variable that persisted associated with physical activity would add an additional benefit of exercise in early prevention of vascular inflammation and atherogenesis. | 23743170 |
| Inflammation, Neoplasms | Altered Intercellular Communication | There have been several reports that members of the regenerating gene (REG) family are highly expressed in chronic inflammation and in tumors of the digestive organs. | 23743605 |
| Inflammation, hepcidin | Altered Intercellular Communication | Hepcidin is a key regulator of iron homeostasis: downregulation in the presence of iron deficiency allows enteral iron resorption, while upregulation in case of chronic inflammation blocks it. | 23743883 |
| Inflammation, Impaired T cell function, Hypoxemia, Chronic Kidney Diseases | Altered Intercellular Communication | Nocturnal hypoxemia contributes to systemic inflammation, oxidative stress, endothelial cell dysfunction, and activation of the renin-angiotensin system, which are common pathologic mechanisms of CKD progression. | 23744006 |
| Coinfection, Inflammation, Hypertension, CTCAE | Altered Intercellular Communication | Coinfection with H. pylori and C. pneumoniae was significantly associated with hypertension compared with double seronegativity after adjustment for age, sex, chronic low-grade inflammation, and cardiovascular risk factors (OR = 1.68; 95% CI = 1.14-2.47; P = 0.008]. | 23744497 |
| Coinfection, Inflammation, Hypertension, CTCAE | Altered Intercellular Communication | However, coinfection with C. pneumoniae and H. pylori showed a significant association with essential hypertension, independent of cardiovascular risk factors and chronic low-grade inflammation. | 23744497 |
| Barrett Esophagus, Inflammation | Altered Intercellular Communication | Barrett esophagus develops in a scenario of chronic inflammation, linked to free radical formation and oxidative DNA damage. | 23744553 |
| Inflammation, Axonal loss, Neuronal loss in central nervous system | Altered Intercellular Communication | Peripheral nerve biopsies in 5 patients showed axonal loss without significant inflammation; a dorsal root ganglion biopsy in 1 patient showed neuronal loss and inflammatory infiltrate. | 23744601 |
| Inflammation, Granulation finding, Vascular System Injuries | Altered Intercellular Communication | Restenosis after stenting is an over-reaction of the wound-healing response after vascular injury, which is characterized by a sequence of inflammation, granulation, extracellular matrix remodeling, and smooth muscle cell proliferation and migration. | 23744617 |
| Inflammation | Altered Intercellular Communication | Endoscopies of the large bowel showed patchy inflammation from the rectum to the hepatic flexure with multiple tiny polyps. | 23744856 |
| Inflammation | Altered Intercellular Communication | A 13-year-old girl was initially observed for several months due to elevated sedimentation rate (ESR 75-90 mm/h) without signs of inflammation or other symptoms and disease signs. | 23745349 |
| Inflammation, Damage | Altered Intercellular Communication | The patients with more pronounced lung damage in the form of ABPA-CB and ABPA-CB-ORF had higher serological parameters suggestive of increased systemic inflammation. | 23745673 |
| Inflammation, Cardiovascular Diseases, Obesity, Blood Glucose | Altered Intercellular Communication | Obesity is a significant health issue worldwide and is associated with chronic, low-grade inflammation predisposing the individual to cardiovascular disease and impaired blood glucose homeostasis. | 23746205 |
| Inflammation | Altered Intercellular Communication | Anthocyanins and phenolic acids from purple carrots are effective at reversing inflammation and metabolic alterations in animal models, potentially through inhibition of inflammatory pathways. | 23746205 |
| Inflammation, Prostate carcinoma | Altered Intercellular Communication | Histological inflammation and risk of subsequent prostate cancer among men with initially elevated serum prostate-specific antigen (PSA) concentration in the Finnish prostate cancer screening trial. | 23746332 |
| Inflammation, Prostate carcinoma, Structure of posterior cerebral artery | Altered Intercellular Communication | To assess whether histological signs of inflammation are associated with an increased risk of subsequent prostate cancer (PCa) in men with elevated serum prostate-specific antigen (PSA) concentrations and benign initial biopsy. | 23746332 |
| Inflammation, Structure of posterior cerebral artery | Altered Intercellular Communication | Histological inflammation in a prostate biopsy among men with an initial false-positive screening test was not associated with an increased risk of subsequent PCa, but instead with a decreased risk which was of borderline significance. | 23746332 |
| Inflammation, Structure of posterior cerebral artery | Altered Intercellular Communication | Inflammation in prostate biopsy is not a useful risk indicator in PCa screening. | 23746332 |
| HD Term Type, Inflammation | Altered Intercellular Communication | We have recently shown that 1 year of pomegranate juice (PJ) intake attenuated OS and inflammation in patients with HD. | 23746559 |
| Inflammation | Altered Intercellular Communication | Degranulation of PMNLs leads to the release of other cell moieties, such as inflammatory mediators and proteases that enhance inflammation. | 23746559 |
| Inflammation | Altered Intercellular Communication | We conclude that PJ intake attenuated the increase in systemic OS and inflammation induced by IV iron administration during the dialysis session. | 23746559 |
| Inflammation, Observation Method - Coagulation | Altered Intercellular Communication | Gender differences in the prospective associations of self-reported sleep quality with biomarkers of systemic inflammation and coagulation: findings from the Heart and Soul Study. | 23746737 |
| Inflammation, Cardiovascular Diseases | Altered Intercellular Communication | Systemic inflammation is proposed as a putative mechanism underlying the link between poor sleep and cardiovascular disease. | 23746737 |
| Inflammation, Choline Dehydrogenase, Mitochondrial | Altered Intercellular Communication | Further research is necessary to elucidate the pathways that underlie gender-specific associations between subjective sleep quality and markers of inflammation and coagulation as this may help clarify gender disparities in CHD. | 23746737 |
| Inflammation, atherosclerotic | Altered Intercellular Communication | Leukotrienes are involved in the physiological mechanism of atherosclerotic events and inflammation. | 23746795 |
| Vascular Diseases, Inflammation, Neoplasms, GCA gene, Giant Cell Arteritis, Pituitary Apoplexy, Brain Infarction | Altered Intercellular Communication | In the group of patients who had vasculopathic risk factors only, with no other significant medical condition, 10% of patients (8/80) were found to have other causes, including midbrain infarction, neoplasms, inflammation, pituitary apoplexy, and giant cell arteritis (GCA). | 23747163 |
| Communicable Diseases, Inflammation | Altered Intercellular Communication | The data from this study showed that immunosuppression, the shift of the Th1/Th2 balance toward a Th2 response, increased Tregs, and related inflammatory cytokines are involved in the complex process of inflammation and infection caused by gut mucosal barrier dysfunction in patients with early SAP. | 23747854 |
| Inflammation, Hemorrhage, Dental Plaque | Altered Intercellular Communication | The Plaque and Bleeding indices of both groups were comparable, and peri-implant inflammation scores in both groups were zero for all implants. | 23748315 |
| Inflammation, Thrombosis, Swelling, Body fluid retention, Achromia of skin | Altered Intercellular Communication | The method is efficient only in those pathological processes accompanied by variable skin depigmentation, water retention, inflammation, thrombosis, or swelling. | 23748801 |
| Chronicity, Granulomatous inflammation, Metaplasia, Chronic Active Colitis | Altered Intercellular Communication | CCS is histologically characterized by chronic active colitis with granulomatous inflammation and Paneth cell metaplasia suggesting chronicity. | 23749110 |
| Colitis, Cytomegaloviral colitis, Granulomatous inflammation, Metaplasia, Chronic Active Colitis, Graft-vs-Host Disease | Altered Intercellular Communication | Chronic active colitis with granulomatous inflammation and Paneth cell metaplasia was present in 12/33 (36%) patients with biopsy-proven GVHD, 4/6 (67%) patients with CMV colitis and 2/15 (13%) patients with nonspecific colitis. | 23749110 |
| Proteinuria, Nephritis, MPV17 gene, Kidney Diseases | Altered Intercellular Communication | MDM2 blockade with nutlin-3a could be a novel therapeutic strategy to prevent renal inflammation, podocyte loss, glomerulosclerosis, proteinuria, and progressive kidney disease. | 23749457 |
| Inflammation | Altered Intercellular Communication | Remission was defined as absence of clinically detectable joint inflammation on a 51-joint count. | 23749581 |
| Inflammation, Primary malignant neoplasm | Altered Intercellular Communication | Systemic inflammation, as evidenced by the Glasgow prognostic score (GPS), predicts cancer-specific survival in various types of cancer. | 23749931 |
| Inflammation, Lymphoma | Altered Intercellular Communication | IgG4-related inflammation of the orbit simulating malignant lymphoma. | 23749941 |
| Inflammation, B-Cell Lymphomas | Altered Intercellular Communication | We report a case of IgG4-related inflammation of the orbit simulating extranodal marginal zone B-cell lymphoma (EMZL). | 23749941 |
| Inflammation, Neoplasms | Altered Intercellular Communication | Based on the clinicopathological findings, tumors 1 and 2 were diagnosed as IgG4-related inflammation and EMZL, respectively. | 23749941 |
| Airway structure, Asthma | Altered Intercellular Communication | It has been reported that fractioned exhaled nitric oxide (FENO) can be used for monitoring airway inflammation and for asthma management but conclusions drawn by different researchers are controversial. | 23756211 |
| Inflammation, Tumor necrosis, Colorectal Carcinoma | Altered Intercellular Communication | Cancer-associated inflammation, in the form of local and systemic inflammatory responses, appear to be linked to tumour necrosis and have prognostic value in patients with colorectal cancer. | 23756867 |
| Inflammation, Diabetes Mellitus, Insulin-Dependent, Destruction of tissue | Altered Intercellular Communication | The extent of periodontal inflammation and tissue destruction and the serum levels of sRANKL (pg/ml) and OPG (pg/ml) were determined in 80 subjects with type 1 diabetes mellitus (T1DM). | 23758409 |
| Inflammation, Metabolic Syndrome X | Altered Intercellular Communication | Metabolic syndrome and abdominal fat are associated with inflammation, but not with clinical outcomes, in peritoneal dialysis patients. | 23758640 |
| Inflammation | Altered Intercellular Communication | In conclusion, these results suggest that BuChE enzymatic activity plays an important role in regulating intrinsic inflammation and activity of cholinoceptive glial cells and that this might be of clinical relevance. | 23759148 |
| Lymphoplasmacytic Infiltrate, Orbital Pseudotumor | Altered Intercellular Communication | High prevalence of IgG4-related lymphoplasmacytic infiltrative disorder in 25 patients with orbital inflammation: a retrospective case series. | 23759440 |
| Orbital Pseudotumor | Altered Intercellular Communication | 25 patients with biopsy-proven idiopathic orbital inflammation examined from January 2006 through December 2011 were included. | 23759440 |
| Orbital Pseudotumor | Altered Intercellular Communication | Finally, 40% of patients with biopsy-proven orbital inflammation were classified as IgG4-RD, with typical histological features, but without specific clinical or radiological findings. | 23759440 |
| Inflammation, Acute Coronary Syndrome, GDC AJCC Clinical Stage Terminology | Altered Intercellular Communication | It is well known that inflammation plays a key role in both initiation and propagation of acute coronary syndrome (ACS). | 23760114 |
| Inflammation | Altered Intercellular Communication | The inflammation assessed using WBC and its subtypes may be more important in young NSTE-ACS patients. | 23760114 |
| Vasculitis, Inflammation, Lupus Erythematosus | Altered Intercellular Communication | The implication of the idea that subclinical vessel inflammation is widespread in patients with lupus-and that this inflammation confers a significant part of the patients' risk of accelerated atherosclerosis-might be a lowering of the threshold for aggressive disease-modifying treatment of lupus, essentially a "treat-to-target" approach to systemic lupus. | 23761181 |
| Inflammation, Tuberculosis, Unknown (origin) (qualifier value), Electrocardiogram: myocardial infarction (finding), Pericarditis, Constrictive, Uremia | Altered Intercellular Communication | Aetiology of constrictive pericarditis was idiopathic in 49 patients (55%), prior cardiac surgery in 21 patients (23.6%), tuberculosis in 5 patients (5.6%), radiation treatment in 5 (5.6%), uraemia in 4 (4.5%), inflammation in 3 (3.5%) myocardial infarction in 2 (2.2%), and perioperative mortality was 7%. | 23761416 |
| Inflammation, Scleritis, Eye pain | Altered Intercellular Communication | Scleritis is an inflammation of the outer eye coating that manifests with redness and ocular pain, and tends to be more severe when associated with a systemic collagen disease. | 23761504 |
| Inflammation, Muscular Atrophy, Skeletal muscle structure | Altered Intercellular Communication | Systemic and tissue inflammation also accelerates skeletal muscle loss, but it is unknown whether inflammation is associated to inactivity-induced muscle atrophy in healthy older adults. | 23761639 |
| Inflammation, Prostate, Benign prostatic hypertrophy | Altered Intercellular Communication | We conclude that the signal detected by the nanodevice, in contrast to individual targets detected with antibodies used in this study, originates from multiple thioredoxin interacting protein partners that distinguish the M2 neutrophil and macrophage associated inflammatory response in prostate cancer-associated stroma from the CD4+ T-Lymphocyte linked inflammation in benign prostatic hyperplasia. | 23762225 |
| Inflammation, Asthma | Altered Intercellular Communication | Association of eosinophilic inflammation with FKBP51 expression in sputum cells in asthma. | 23762334 |
| Inflammation, Asthma | Altered Intercellular Communication | To evaluate the relationship between eosinophilic inflammation and FKBP51 expression in sputum cells in asthma. | 23762334 |
| Inflammation, Asthma | Altered Intercellular Communication | Lower FKBP51 expression in sputum cells may reflect eosinophilic inflammation and glucocorticoid responsiveness in steroid-naive asthmatic patients. | 23762334 |
| Inflammation, Cardiac complication, Diabetes Mellitus | Altered Intercellular Communication | Adaptive immunity, inflammation, and cardiovascular complications in type 1 and type 2 diabetes mellitus. | 23762872 |
| Inflammation | Altered Intercellular Communication | In our study, we investigated the role of systemic inflammation and T-cell subsets in T1- and T2DM and the possible mechanisms underlying the increased cardiovascular risk associated with these diseases. | 23762872 |
| Refractory anemias, Rheumatoid Arthritis, Autoimmune Diseases, Inflammation | Altered Intercellular Communication | Rheumatoid arthritis (RA) is an autoimmune disease that causes chronic inflammation of the joints affecting multiple organs in the body. | 23763224 |
| Inflammation, Fibrosis Assessment, Branchioma, Necrosis | Altered Intercellular Communication | On the pathology report the pericardial mass resection showed mild chronic inflammation, extensive fibrosis, fat necrosis and branchial cyst surrounded with mild chronic inflammation. | 23763224 |
| Airway structure | Altered Intercellular Communication | However, abnormally elevated ATP levels have been reported in inflamed airways, suggesting that excessive ATP in ASL contributes to airway inflammation. | 23763446 |
| Airway structure, Fibrosis Assessment | Altered Intercellular Communication | In this study, links between cystic fibrosis (CF)-associated airway inflammation and airway epithelial ATP release were investigated. | 23763446 |
| Airway structure | Altered Intercellular Communication | We propose that CF airway inflammation up-regulates the capacity of airway epithelia to release ATP via Ca(2+)-dependent vesicular mechanisms not associated with mucin granule secretion. | 23763446 |
| Inflammation, Chronic Kidney Diseases | Altered Intercellular Communication | We investigated whether the effect of inflammation on C-reactive protein (CRP) and ferritin levels is being overlooked in indigenous patients with chronic kidney disease. | 23763720 |
| Inflammation, Hepatobiliary Disorder, Autoimmune Chronic Hepatitis, Insemination, Artificial, Homologous | Altered Intercellular Communication | Autoimmune hepatitis (AIH) is a chronic liver disease caused by inflammation of the liver. | 23763817 |
| Inflammation, Fibrosis Assessment, Neoplasms | Altered Intercellular Communication | It was correlated with tumor progression, but not with the degree of liver fibrosis and inflammation. | 23764929 |
| Chronic cholangitis, Inflammation, Primary Biliary Cholangitis | Altered Intercellular Communication | We have reported that fractalkine expression associated with chronic inflammation is observed in the damaged bile ducts and periductal vessels of PBC patients, which is closely associated with chronic cholangitis. | 23765258 |
| Inflammation, Lower Urinary Tract Symptoms | Altered Intercellular Communication | PDE5 inhibitors blunt inflammation in human BPH: a potential mechanism of action for PDE5 inhibitors in LUTS. | 23765639 |
| Inflammation | Altered Intercellular Communication | Chronic inflammation is one of the putative links between these diseases. | 23765639 |
| Inflammation, Prostate | Altered Intercellular Communication | In this study we investigate whether PDE5i could blunt inflammation in the human prostate. | 23765639 |
| Inflammation, Anger | Altered Intercellular Communication | Varieties of anger and the inverse link between education and inflammation: toward an integrative framework. | 23766379 |
| social inequality, Inflammation, Anger | Altered Intercellular Communication | To examine multiple aspects of anger experience and expression (frequency, outward expression, suppression, and control) as moderators of the association of social inequality, as measured by educational status, with inflammation and coagulation markers. | 23766379 |
| ARCN1 gene, Chronic Obstructive Airway Disease, Pneumonitis | Altered Intercellular Communication | The etiology of chronic obstructive pulmonary disease (COPD) is chronic lung inflammation. | 23767419 |
| Inflammation, Fever, CTCAE, Neurologic (qualifier value), Back Pain, Neuralgia | Altered Intercellular Communication | Apart of a chronic neuropathic foot wound, the patients reported severe or deteriorated dorsal pain (2 in the lumbal region, one in thoracic spine), had no new neurologic lesion in the beginning, some had fever, but all had high laboratory parameters of inflammation that did not correlate with local finding on the foot. | 23767458 |
| Dysmotility, Gastroparesis, Inflammation, Infection caused by Helicobacter pylori | Altered Intercellular Communication | The low prevalence of H. pylori infection in gastroparesis could be explained by higher rates of previous eradication, conditions unfavourable to the survival of H. pylori, or a protective effect of mucosal inflammation against the development of motility disorders. | 23768443 |
| Inflammation, Malignant neoplasm of larynx, Malignant Neoplasms | Altered Intercellular Communication | Chronic inflammation has been implicated in the pathogenesis of several cancers, including lung and laryngeal cancer. | 23768737 |
| Inflammation, Liver Cirrhosis | Altered Intercellular Communication | Microscopic findings revealed micronodular cirrhosis with mixed inflammation in the portal areas. | 23769108 |
| Inflammation, Diabetes Mellitus, Non-Insulin-Dependent, fibrogenesis | Altered Intercellular Communication | Plasma galectin-3, a mediator of fibrogenesis and inflammation, its potential to associate with type 2 diabetes (T2DM) is poorly investigated. | 23769567 |
| Inflammation, anatomical bulb, Hyperemia | Altered Intercellular Communication | Objective tarsal conjunctiva inflammation, bulbar conjunctiva findings (such as hyperemia and thickening), cornea staining, and subjective symptoms were evaluated. | 23770977 |
| Inflammation, Fibrosis Assessment | Altered Intercellular Communication | We investigated whether such a pattern was also found in biopsies from ingrown toenails, which can be greatly distorted through inflammation and fibrosis. | 23771067 |
| Inflammatory abnormality of the eye | Altered Intercellular Communication | The ocular inflammation can be the first symptom of syphilis. | 23771257 |
| Primary central nervous system lymphoma, Inflammation, Demyelination, Lymphoproliferative Disorders | Altered Intercellular Communication | Dynamic susceptibility-weighted contrast-enhanced perfusion MRI using ferumoxytol showed low rCBV (ratio <1.0) in 3 cases of demyelination or inflammation, modestly elevated rCBV in 5 cases of CNS lymphoma or lymphoproliferative disorder (range: 1.3-4.1), and no measurable disease in one case. | 23771486 |
| Inflammation, Weight decreased, Overweight | Altered Intercellular Communication | To determine the independent effect of long-term physical activity (PA) and the combined effects of long-term PA and weight loss (WL) on inflammation in overweight and obese older adults. | 23772804 |
| Inflammation, Chronic granulomatous disease | Altered Intercellular Communication | These findings suggest that elevated BAFF in CGD subjects and healthy donors is a consequence of acute and chronic inflammation. | 23773925 |
| Inflammation, Aortitis | Altered Intercellular Communication | Medial inflammation was predominantly lymphohistiocytic and was marked in 3 cases but limited to the region adjacent to the dissection plane, unlike aortitis. | 23774175 |
| Inflammation, Traumatic injury, Rupture | Altered Intercellular Communication | Adventitial inflammation is prominent soon after intimal injury in aortic dissections before rupture of the false lumen. | 23774175 |
| Inflammation, Aortitis | Altered Intercellular Communication | The pattern of inflammation is distinct from aortitis and can be used to date early aortic dissections. | 23774175 |
| Inflammation, Atherosclerosis | Altered Intercellular Communication | Persistent inflammation plays a role in the pathogenesis of atherosclerosis. | 23774275 |
| Inflammation | Altered Intercellular Communication | We next delivered the AAVs to mouse brains neurosurgically, and demonstrated that Acat1-targeting AAVs could express viral proteins and effectively diminish ACAT activity in vivo, without inducing appreciable inflammation. | 23774792 |
| Inflammation, Fibrosis Assessment, Injury of liver | Altered Intercellular Communication | Experimental liver injury models have indicated that natural killer (NK) cells are critical regulators of inflammation and fibrosis. | 23774822 |
| Inflammation, Fibrosis Assessment, Cholestasis | Altered Intercellular Communication | By multiple regression analysis, bile ductular plugs, morphometric assessment of fibrosis, rosetting, portal tract inflammation and pattern of cholestasis were found to be significant in discriminating the two groups. | 23775681 |
| Inflammation, Early-onset | Altered Intercellular Communication | Greater inflammation may contribute to the precipitous disease course typically seen in early-onset patients. | 23775979 |
| Inflammation, Pouchitis | Altered Intercellular Communication | The natural history of anal transition zone inflammation and possible relationship to pouchitis: a long-term longitudinal study. | 23777389 |
| Inflammation, Infection, Immune System Diseases, Uveitis | Altered Intercellular Communication | Specific causes of uveitis included infections (34.4%), with syphilis responsible for 16.4% of all cases, and defined immunological disorders (27.0%); no cause for the inflammation was identified in 34.4% of persons. | 23777456 |
| Inflammation, Tuberculosis | Altered Intercellular Communication | Histological examination revealed granulomatouse inflammation with numerous acid fast bacilli consist with tuberculosis. | 23777575 |
| Communicable Diseases, Inflammation | Altered Intercellular Communication | (3) and (4) indicate intense inflammation caused by local infection. | 23777595 |
| Adenoma, Toxic effect | Altered Intercellular Communication | Genetic polymorphisms in multiple inflammation-related genes appear to interact with celecoxib on adenoma recurrence and its attendant toxicity, particularly cardiovascular toxicity/symptoms. | 23778325 |
| Inflammation, Dyslipidemias | Altered Intercellular Communication | Recent research has emphasized the strong association between inflammation and both P-wave dispersion and dyslipidemia. | 23778479 |
| Inflammation, Renal Cell Carcinoma | Altered Intercellular Communication | Markers of systemic inflammation predict survival in patients with advanced renal cell cancer. | 23778526 |
| Refractory Cytopenia of Childhood, Inflammation | Altered Intercellular Communication | Markers of systemic inflammation contribute significantly to prognostic classification in addition to established factors for pre-treated patients with advanced RCC. | 23778526 |
| Autistic behavior, Inflammation | Altered Intercellular Communication | Both ASD groups demonstrated significantly higher 3CT levels than control subjects, suggesting that chronic inflammation was present in both groups of children with ASD. | 23778583 |
| Inflammation, Periodontitis | Altered Intercellular Communication | The magnitude of the association between shift work and periodontitis attenuated with adjustment of mediators (smoking and a marker of inflammation). | 23780580 |
| Communicable Diseases, Tooth structure, Inflammation | Altered Intercellular Communication | During extraction of the tooth, infection, decay, and inflammation were discovered. | 23780593 |
| Gingivitis, Tooth structure, Dental caries | Altered Intercellular Communication | The dental assessment comprised the number of teeth, caries frequency (DMFT index), type and frequency of restorations, quality of oral hygiene (API), degree of gingival inflammation (SBI), probing depths and the presence of recessions. | 23780856 |
| Inflammation | Altered Intercellular Communication | Faecal calprotectin and a1-antitrypsin concentrations may be associated with mucosal permeability and inflammation. | 23782263 |
| Inflammation, Complication Aspects, Metabolic Syndrome X, ETV3 wt Allele, Non-alcoholic Fatty Liver Disease, Obesity, Overweight | Altered Intercellular Communication | Iron (Fe) sequestration is described in overweight and in its associated metabolic complications, i.e., metabolic syndrome (MetS) and non-alcoholic liver fatty disease (NAFLD); however, the interactions between Fe, obesity and inflammation make it difficult to recognize the specific role of each of them in the risk of obesity-induced metabolic diseases. | 23783556 |
| Primary malignant neoplasm | Altered Intercellular Communication | Recent studies have shown that the modified Glasgow Prognostic Score (mGPS), which is an inflammation-based prognostic score, is useful as a prognostic index for some cancer cases. | 23784105 |
| Inflammation, Fibrosis Assessment | Altered Intercellular Communication | The transcriptome changes in 3-month-old DMD pigs were in good concordance with gene expression profiles in human DMD, reflecting the processes of degeneration, regeneration, inflammation, fibrosis and impaired metabolic activity. | 23784375 |
| Necrotizing granulomatous inflammation, Pancreatitis, Malignant Neoplasms, Sarcoidosis | Altered Intercellular Communication | Histology showed changes of chronic pancreatitis and peripancreatic granulomatous inflammation with no evidence of malignancy and a diagnosis of sarcoidosis was made. | 23784760 |
| Neoplasms, Traumatic, Aneurysm, Posterior Communicating Artery, Hernia | Altered Intercellular Communication | They are ischaemic microangiopathy, posterior communicating artery aneurysm, uncal herniation, neoplasia, traumatic and inflammatory conditions. | 23784767 |
| Malignant - descriptor, Lymphoma, T-Cell, Cutaneous, Dermatitis | Altered Intercellular Communication | In leukemic cutaneous T-cell lymphoma (L-CTCL), malignant T cells accumulate in the blood and give rise to widespread skin inflammation. | 23785046 |
| Airway structure, Weight decreased | Altered Intercellular Communication | Systemic and airway inflammation did not change following weight loss. | 23786284 |
| Inflammation, Hypertension, CTCAE, IL13 gene, Disease | Altered Intercellular Communication | Whether the inflammation caused by allergic diseases such as allergic rhinitis can predispose to hypertension is controversial. | 23786432 |
| Inflammation | Altered Intercellular Communication | Hair characteristics and scalp inflammation were assessed by an interviewer-administered questionnaire. | 23786579 |
| Inflammation, Lipohypertrophy, CTCAE | Altered Intercellular Communication | Central lipohypertrophy was not associated with change in scalp hair texture or scalp inflammation in this cohort. | 23786579 |
| Inflammation, Thrombosis | Altered Intercellular Communication | Activated platelets play a role in atherogenesis, inflammation and atherothrombosis. | 23786593 |
| Airway structure, ARCN1 gene, Chronic Obstructive Airway Disease | Altered Intercellular Communication | Cyclooxygenase-2 (COX-2) is overexpressed during airway inflammation in chronic obstructive pulmonary disease (COPD) patients. | 23786928 |
| Multiple Organ Failure, Inflammation, SLC25A10 gene | Altered Intercellular Communication | The JAAM DIC patients were more seriously ill and exhibited more severe systemic inflammation, a higher prevalence of multiple organ dysfunction syndrome (MODS) and worse outcomes than the non-DIC patients. | 23787004 |
| Multiple Organ Failure, Inflammation | Altered Intercellular Communication | Disease severity, systemic inflammation, MODS and the mortality rate worsened in accordance with an increased JAAM DIC score on day 1. | 23787004 |
| Inflammation, Primary malignant neoplasm, Anemia, Toxic effect | Altered Intercellular Communication | Anemia, a frequent and deleterious condition in patients with cancer, is mainly caused by chemotherapy toxicity, iron deficiency, or inflammation. | 23787470 |
| Airway structure, airway disease | Altered Intercellular Communication | Sputum differential count is a useful tool to evaluate airway inflammation in chronic airway diseases. | 23787521 |
| Inflammation | Altered Intercellular Communication | Angiogenesis may be induced by intramyocardial injection of autologous bone marrow stem cells, intensified by inflammation around channels performed by laser. | 23788089 |
| Inflammation, Toxic effect, Hypotension, CTCAE, Syncope (amphibian), Abdominal Pain, Fatigue | Altered Intercellular Communication | Five patients experienced grade 3 non-haematological toxicity, including symptoms of urothelial inflammation, hypotension and syncope, fatigue and abdominal pain. | 23789936 |
| Cholecystitis, Cholestasis | Altered Intercellular Communication | We are reporting a rare case of obstructive cholestasis and cholecystitis due to CMV-related inflammation of the major duodenal papilla in a 60-year-old woman 3 months after renal transplantation. | 23790000 |
| Airway structure, Asthma | Altered Intercellular Communication | Persistent airway inflammation, detected by fractional exhaled nitric oxide (FENO), is occasionally observed in asthmatic patients, even in those treated with inhaled corticosteroids (ICS). | 23790736 |
| Inflammation, Hemorrhage, Meckel Diverticulum, Perforation (observation), Intestinal Obstruction | Altered Intercellular Communication | Meckel's diverticulum may give rise to bleeding, intestinal obstruction and inflammation; however, its perforation by a foreign body is an extremely rare life-threatening complication. | 23790794 |
| Chronic inflammation, Transitional epithelial cell of urinary bladder, Nephrogenic metaplasia | Altered Intercellular Communication | Nephrogenic adenoma is an uncommon urothelial lesion that has been associated with chronic inflammation and surgical manipulation of the urinary tract. | 23791211 |
| Inflammation, Comorbidity | Altered Intercellular Communication | Comorbidity, systemic inflammation and outcomes in the ECLIPSE cohort. | 23791463 |
| ARCN1 gene, Inflammation | Altered Intercellular Communication | Comorbidities, are common in COPD, have been associated with poor outcomes and are thought to relate to systemic inflammation. | 23791463 |
| Heart Diseases, Inflammation, Hypertension, CTCAE, Diabetes Mellitus | Altered Intercellular Communication | The comorbidities of heart disease, hypertension and diabetes are associated with increased systemic inflammation. | 23791463 |
| Airway structure, Thickened, Eosinophilic inflammation | Altered Intercellular Communication | Periostin, an extracellular matrix protein, contributes to subepithelial thickening in asthmatic airways, and its serum levels reflect airway eosinophilic inflammation. | 23791506 |
| Inflammation, Obesity | Altered Intercellular Communication | The relationship between obesity, physical fitness, and inflammation was analyzed in a Polish population aged 12 to 18 years. | 23792582 |
| IgG4-Related Sclerosing Disease | Altered Intercellular Communication | IgG4-related disease (IgG4-RD) is a recently described inflammatory condition known to cause tumefactive lesions at myriad anatomical locations. | 23793110 |
| Inflammation | Altered Intercellular Communication | A higher degree of systemic inflammation, reflected by the ESR and CRP level, was associated with a smaller proportion of patients consuming alcohol. | 23793744 |
| Inflammation, Colorectal Carcinoma | Altered Intercellular Communication | These findings suggest the importance of inflammation and angiogenesis in the etiology of colorectal cancer and that genetic and lifestyle factors may be targets for modulating disease risk. | 23794399 |
| Airway structure | Altered Intercellular Communication | Increased induced sputum levels of NGAL might be a characteristic feature of overlap, suggesting enhanced neutrophilic airway inflammation and/or airway epithelial injury in COPD-asthma overlap. | 23794464 |
| Airway structure, Pneumonitis | Altered Intercellular Communication | Rosiglitazone and pioglitazone attenuated airway neutrophilia in a corticosteroid-resistant mouse model of pulmonary inflammation. | 23794466 |
| Inflammation, Fibrosis Assessment | Altered Intercellular Communication | When compared with healthy controls, serum hyaluronan was significantly greater in patients with CIP and was positively correlated with serum biomarkers of inflammation and fibrosis, such as C-reactive protein and surfactant protein-D. | 23795990 |
| Hepatitis B, Acute and chronic inflammation, Liver Cirrhosis | Altered Intercellular Communication | Hepatitis B virus (HBV)-related cirrhosis is known to be associated with chronic hepatic inflammation. | 23796976 |
| Autoimmune Pancreatitis, Cardiomyopathies, Autoimmune reaction | Altered Intercellular Communication | [Peripartum cardiomyopathy, acute autoimmune pancreatitis and periadipose tissue inflammation - autoimmune reaction?]. | 23797439 |
| Pancreatitis, Acute, Inflammation, Organ dysfunction syndrome, Cardiomyopathies | Altered Intercellular Communication | A case of 26 year-old female with peripartum cardiomyopathy, acute pancreatitis, periadipose tissue inflammation due to unknown cause and multiple organ dysfunction syndrome complication is presented. | 23797439 |
| Inflammation, Colorectal Carcinoma, Ulcerative Colitis | Altered Intercellular Communication | Earlier studies suggest that the severity of inflammation is an independent risk factor for CRC in ulcerative colitis (UC). | 23797639 |
| Inflammatory Bowel Diseases, Inflammation, Dysplasia, Colorectal Intraepithelial Neoplasia, Colorectal Carcinoma | Altered Intercellular Communication | We investigated the role of histological inflammation as a risk factor for colorectal dysplasia or CRC to better target dysplasia surveillance in IBD. | 23797639 |
| Inflammation, Dysplasia, Colorectal Carcinoma | Altered Intercellular Communication | Histological severe inflammation was present in 41.4% of patients with dysplasia and in 24.1% of patients with CRC, but in only 4.3% of controls. | 23797639 |
| Inflammation, Dysplasia, Carcinoma | Altered Intercellular Communication | Severe inflammation had an odds ratio (OR) of 31.8 [95% confidence interval (CI): 15.6-64.9] for dysplasia or carcinoma compared to patients with no inflammation. | 23797639 |
| Inflammation, Dysplasia, Colorectal Carcinoma | Altered Intercellular Communication | As conclusion, degree of inflammation and duration of disease cumulatively increase the risk for dysplasia and CRC. | 23797639 |
| Autoimmune Diseases, Idiopathic Inflammatory Myopathies, Myositis | Altered Intercellular Communication | Idiopathic inflammatory myopathies (IIM) are a rare group of autoimmune diseases characterized by muscle inflammation. | 23797759 |
| Airway structure, Asthma, Bronchial Hyperreactivity | Altered Intercellular Communication | Airway inflammation and bronchial hyperreactivity in steroid naive children with intermittent and mild persistent asthma. | 23798479 |
| Airway structure | Altered Intercellular Communication | To our knowledge, there is no study comparing airway inflammation between intermittent and mild persistent asthmatic children. | 23798479 |
| Airway structure | Altered Intercellular Communication | Eosinophilic airway inflammation and direct BHR may not be significantly different in intermittent asthmatic children from their peers with mild persistent disease. | 23798479 |
| Inflammation, Cell Death | Altered Intercellular Communication | In conclusion, mass spectrometric investigation of exudates from chronic wounds demonstrated dramatic impairment in wound repair with excessive inflammation, antiangiogenic environment, and accelerated cell death. | 23798543 |
| Arterial Stiffness, Left Ventricular Hypertrophy, Inflammation, Hypertension, CTCAE | Altered Intercellular Communication | Serum 25-hydroxyvitamin D level is associated with arterial stiffness, left ventricle hypertrophy, and inflammation in newly diagnosed hypertension. | 23799341 |
| Myocardial fibrosis, vascular inflammations, vascular smooth muscle cell proliferation | Altered Intercellular Communication | Vitamin D may modulate vascular inflammation, vascular smooth muscle cell proliferation, the renin-angiotensin system, and cardiomyocyte proliferation, myocardial fibrosis, and proliferation. | 23799341 |
| Arterial Stiffness, Left Ventricular Hypertrophy, Inflammation | Altered Intercellular Communication | Serum 25-hyroxyvitamin D is independently related with arterial stiffness, LVH, and inflammation. | 23799341 |
| Inflammation, Colorectal Carcinoma | Altered Intercellular Communication | Comparison of the prognostic value of longitudinal measurements of systemic inflammation in patients undergoing curative resection of colorectal cancer. | 23799846 |
| Colorectal Carcinoma, Malignant Neoplasms | Altered Intercellular Communication | The systemic inflammation-based prognostic scores, modified Glasgow Prognostic Score (mGPS) and the neutrophil-lymphocyte ratio (NLR) are now recognised to be useful in predicting survival in a variety of solid organ malignancies, including colorectal cancer (CRC) before treatment. | 23799846 |
| Inflammation, Tooth structure | Altered Intercellular Communication | The tooth was mobile but with minimal inflammation. | 23801078 |
| Inflammation, Lymphoproliferative Disorders, Anemia, Angiolymphoid hyperplasia, Thrombocytosis | Altered Intercellular Communication | Multicentric Castleman's disease (MCD) is a polyclonal lymphoproliferative disorder that manifests as marked hyper-g-globulinemia, severe inflammation, anemia, and thrombocytosis. | 23801138 |
| Inflammation, Fever, CTCAE, Aplastic Anemia, Anasarca | Altered Intercellular Communication | Case 2: A 73-year-old man with a history of aplastic anemia and remission presented with fever, severe inflammation, and anasarca. | 23801138 |
| Inflammation, Atherosclerosis | Altered Intercellular Communication | C-reactive protein (CRP) is a marker of inflammation, which promotes atherosclerosis. | 23801460 |
| ARCN1 gene, Inflammation, Chronic Obstructive Airway Disease | Altered Intercellular Communication | Although researchers have consistently demonstrated systemic inflammation in chronic obstructive pulmonary disease (COPD), its origin is yet unknown. | 23801879 |
| Pain Distress Question, Psoriasis, Refractory anemias, Rheumatoid Arthritis, Pruritus | Altered Intercellular Communication | Symptoms of itch and pain in chronic inflammatory conditions of psoriasis (PS) and rheumatoid arthritis (RA) can highly affect patients' quality of life. | 23802713 |
| Pain Distress Question, Pruritus | Altered Intercellular Communication | This study directly compared whether patients with chronic inflammatory conditions associated with chronic itch or pain display a heightened sensitivity to itch and pain, respectively. | 23802713 |
| Refractory anemias, Pain Distress Question, Pruritus | Altered Intercellular Communication | In line with previous studies in other patient groups with chronic itch or pain, further support was found that somatosensory stimuli are processed in line with the patients' main symptom through generic sensitization processes, also in chronic inflammatory conditions such as PS and RA. | 23802713 |
| Inflammation, Prostatic Diseases, Prostate carcinoma, Benign prostatic hypertrophy, Structure of posterior cerebral artery | Altered Intercellular Communication | The role of inflammation in prostate diseases is suggested by the presence of inflammatory cells within the prostate in benign prostatic hyperplasia (BPH) and prostate cancer (PCa) patients. | 23803120 |
| Inflammation, Prostate | Altered Intercellular Communication | In addition, bacterial and viral infection may lead to chronic and recurrent inflammation of the prostate. | 23803120 |
| Human papilloma virus infection, Inflammation, Prostatic Diseases, Prostate carcinoma | Altered Intercellular Communication | Our data do not support a significant role of HPV infection in prostatic disease in Iranian patients, but demographic data indicated a probable association between presence of HPV DNA and risk of inflammation in prostate tissue which might lead to prostate carcinoma. | 23803120 |
| Inflammation, Cyst of vagina | Altered Intercellular Communication | Postpartum vaginal cystic lesions constitute a common situation that is caused either by inflammation or by accumulation of lymph. | 23803247 |
| Inflammation, Fibrosis Assessment, Fatty Liver Disease | Altered Intercellular Communication | Serum L-FABP levels are elevated in NASH and this elevation is positively correlated with the degree of fibrosis and inflammation. | 23803374 |
| Inflammation, Fibrosis Assessment, Fatty Liver Disease | Altered Intercellular Communication | L-FABP levels may aid as a non-invasive marker in determining the severity of fibrosis and inflammation in patients with NASH. | 23803374 |
| Inflammation, RTEL1 gene, Obesity | Altered Intercellular Communication | Obesity is associated with inflammation, a cytokine milieu conducive to lymphocyte proliferation, and has been associated with NHL risk in some epidemiologic studies. | 23803416 |
| Vitreous inflammatory cells | Altered Intercellular Communication | B-scan ultrasonography showed multiple clumplike echoes suggestive of vitreous inflammation. | 23803484 |
| Inflammation, Blood coagulation, Autonomic nervous system disorders | Altered Intercellular Communication | In conclusion, indoor air pollution is associated with inflammation, oxidative stress, blood coagulation and autonomic dysfunction. | 23803502 |
| Inflammation, Colorectal Neoplasms, Hereditary | Altered Intercellular Communication | Inherited variation in genes that regulate innate immunity and inflammation may contribute to colorectal neoplasia risk. | 23803696 |
| Colorectal Neoplasms | Altered Intercellular Communication | Although the results need to be replicated, our findings suggest that genetic variation in inflammation-related genes may be related to the risk of colorectal neoplasia. | 23803696 |
| Inflammation, Obesity, Abdominal | Altered Intercellular Communication | This dysfunction was best predicted by abdominal obesity, inflammation, glucose-intolerance, and systolic dyssynchrony. | 23804526 |
| Diabetes Mellitus, Non-Insulin-Dependent | Altered Intercellular Communication | Resistin is associated with local and systemic inflammatory conditions with a direct correlation with type 2 diabetes mellitus (T2DM). | 23805816 |
| Inflammation, Metabolic Syndrome X | Altered Intercellular Communication | Correlations of ADMA serum levels with disease activity, systemic inflammation and metabolic syndrome were assessed. | 23806325 |
| Airway structure, Asthma | Altered Intercellular Communication | The majority of patients with severe adult-onset asthma are nonatopic and have persistent eosinophilic airway inflammation. | 23806634 |
| Inflammation, Metabolic Diseases, Schizophrenia | Altered Intercellular Communication | Inflammation can be a process significant to the development of schizophrenia and metabolic disorders that are frequently found in patients suffering from schizophrenia. | 23806968 |
| Eye pain, Inflammatory abnormality of the eye, Corneal edema | Altered Intercellular Communication | Ocular pain and visual acuity improved and corneal edema and ocular inflammation decreased after the surgery. | 23807009 |
| Inflammation, hepcidin | Altered Intercellular Communication | The synthesis of hepcidin is upregulated by high iron stores and inflammation. | 23807042 |
| Inflammation, hepcidin | Altered Intercellular Communication | It seems that the influence of inflammation on hepcidin levels in haemodialysed patients is not crucial and other factors (e.g. | 23807042 |
| Fibrous, Inflammatory Hepatocellular Adenoma, Inflammation, Focal Nodular Hyperplasia | Altered Intercellular Communication | Inflammatory hepatocellular adenoma can show overlapping histological features with focal nodular hyperplasia, including inflammation, fibrous stroma, and ductular reaction. | 23807780 |
| Inflammation | Altered Intercellular Communication | The Inflammatory Nutritional Index significantly varied in relation to nutritional status independent of the systemic inflammation (p=0.02). | 23808449 |
| Inflammation, Primary malignant neoplasm | Altered Intercellular Communication | Inflammatory Nutritional Index can be an adjuvant way for biochemical nutritional assessment and follow up in cancer patients with systemic inflammation. | 23808449 |
| Inflammation, Hepatitis | Altered Intercellular Communication | iNKT dominating rodent liver are implicated in inflammation, including in hepatitis models. | 23808994 |
| Inflammation, Edema | Altered Intercellular Communication | There was no imaging evidence of oedema or inflammation. | 23809264 |
| Inflammation, Edema | Altered Intercellular Communication | Imaging does not demonstrate inflammation or oedema in relation to these lesions. | 23809264 |
| Myocarditis | Altered Intercellular Communication | Because, myocardial-FDG uptake occurs with diverse physiology, it should be suppressed during evaluation of myocardial inflammation by FDG-PET/CT. | 23810066 |
| Heart Diseases, Coronary Arteriosclerosis | Altered Intercellular Communication | Cortisol, a key stress hormone, is associated with coronary atherosclerosis and may accentuate structural and functional cardiac disease. | 23810896 |
| Inflammation, Phlebitis, CCR8 protein, human | Altered Intercellular Communication | CCL1-CCR8 interaction may play a critical role in lymphocytic recruitment in IgG4-SC/AIP, leading to duct-centred inflammation and obliterative phlebitis. | 23811304 |
| Inflammation, Ulcerative Colitis | Altered Intercellular Communication | The influence of Toll like receptor 4 (TLR-4) gene polymorphisms on IL-17 production has also been revealed in UC patients and tissue inflammation in mice. | 23811547 |
| Inflammation, Demyelination | Altered Intercellular Communication | Open biopsy revealed inflammation and demyelination, but no malignant cells were detected. | 23812076 |
| Inflammation, Nerve Degeneration | Altered Intercellular Communication | Thus, HPA axis hyperactivity in MS coincides with low inflammation and/or high neurodegeneration, and may impact on lesion pathology and molecular mechanisms in NAWM and thereby be of great importance for suppression of disease activity. | 23812288 |
| Acute Coronary Syndrome | Altered Intercellular Communication | Inflammation impairs eNOS activation by HDL in patients with acute coronary syndrome. | 23812298 |
| Carcinogenic Chlorinated Hydrocarbon | Altered Intercellular Communication | Our data indicated that the higher frequency of inhibitory NK cells combined with fewer activated NK cells may be associated with HCV-related chronic inflammation involved in CHC pathogenesis. | 23813131 |
| Inflammation, Cardiovascular morbidity | Altered Intercellular Communication | Persistent inflammation and oxidative stress play a pathogenic role in the high cardiovascular morbidity and mortality of hemodialysis patients. | 23813560 |
| Inflammation | Altered Intercellular Communication | Systemic inflammation as assessed by CRP has been associated with averse events after DES implantation. | 23813627 |
| Inflammation, Adult Non-Hodgkin Lymphoma | Altered Intercellular Communication | A prospective study of 67 serum immune and inflammation markers and risk of non-Hodgkin lymphoma. | 23814017 |
| Inflammation, Ulcer | Altered Intercellular Communication | Biopsy from the esophageal ulcers revealed dense inflammation infiltrated with lymphocytes and macrophages with clusters of strongly positive intracellular fungal spores with a clear area or "halo-like" zone suggestive of Histoplasma capsulatum invasion. | 23816727 |
| Infarction, Inflammation, Exophthalmos | Altered Intercellular Communication | Magnetic resonance imaging of the head and sinuses showed inflammation and mass in the ethmoid sinus and nose with partial septal destruction, proptosis, global destruction of the left eye, brain infarction and carotid artery obliteration. | 23816728 |
| Primary malignant neoplasm, Neoplasms | Altered Intercellular Communication | A study of inflammation-based predictors of tumor response to neoadjuvant chemoradiotherapy for locally advanced rectal cancer. | 23816828 |
| Acute Lung Injury, Inflammation, Endothelium | Altered Intercellular Communication | One-lung ventilation during esophagectomy is associated with inflammation, alveolar epithelial and systemic endothelial injury, and the development of acute lung injury (ALI). | 23817506 |
| Inflammation, Endothelium | Altered Intercellular Communication | In this proof of concept study, pretreatment with simvastatin in esophagectomy decreased biomarkers of inflammation as well as pulmonary epithelial and systemic endothelial injury. | 23817506 |
| ARCN1 gene, Inflammation, Chronic Obstructive Airway Disease | Altered Intercellular Communication | Whether guideline-oriented pharmacotherapy prevents the decline in pulmonary function or reduces systemic inflammation associated with chronic obstructive pulmonary disease (COPD) is uncertain. | 23817861 |
| ARCN1 gene, Inflammation, Alveolar | Altered Intercellular Communication | Guideline-oriented pharmacotherapy of COPD improves airflow limitation but does not prevent the alveolar destruction and systemic inflammation under real-world conditions in Taiwan. | 23817861 |
| Refractory anemias, Inflammation, physiopathological | Altered Intercellular Communication | Maintaining normal serum vitamin D levels may protect against IL-17-mediated inflammation and vascular dysfunction in RA. | 23818717 |
| Inflammation, Critical Illness | Altered Intercellular Communication | Critically ill patients experience severe stress, inflammation and clinical conditions which may increase the utilization and metabolic turnover of vitamin B-6 and may further increase their oxidative stress and compromise their antioxidant capacity. | 23819116 |
| Inflammation, Venous Thrombosis, Necrosis | Altered Intercellular Communication | Early complications were not observed, while late ones concerned 16.86% of patients and included: generalized bacteriemia (8.43%), local inflammation of the skin and of the subcutaneous tissue (1.2%), venous thrombosis (2.41%), migration of the catheter (1.2%), necrosis of the skin over the port's chamber (2.41%). | 23819398 |
| Neurodegeneration due to 3-hydroxyisobutyryl coenzyme A hydrolase deficiency, Arthritis | Altered Intercellular Communication | A global metabolic profile is identified from all arthritic patients, suggesting that there are common metabolic defects resulting from joint inflammation and lesion. | 23819623 |
| Kidney Failure, Chronic, Inflammation | Altered Intercellular Communication | Chronic inflammation was found to be correlated with coronary (CAC) and thoracic peri-aortic calcification (TAC) in end-stage renal disease (ESRD) patients. | 23819627 |
| Heart Diseases, Inflammation | Altered Intercellular Communication | Neutrophil-to-lymphocyte ratio (NLR) was introduced as a potential marker to determine inflammation in cardiac and noncardiac disorders. | 23819627 |
| Inflammation, Impaired lung function, Symptoms, Chronic Obstructive Airway Disease, Chronic disease, Disability | Altered Intercellular Communication | High rates of disability associated with chronic airway obstruction may be caused by impaired pulmonary function, pulmonary symptoms, other chronic diseases, or systemic inflammation. | 23819728 |
| Inflammation, Rupture, Atherosclerosis | Altered Intercellular Communication | Matrix metalloproteinase-9 (MMP-9) plays an important role in inflammation and matrix degradation involved in atherosclerosis and plaque rupture. | 23819814 |
| Inflammation, Primary malignant neoplasm | Altered Intercellular Communication | Inflammation has a critical role in the pathogenesis and progression of cancer. | 23820252 |
| Inflammation, Muscle damage | Altered Intercellular Communication | While inflammation causes muscle damage in the early phase, metabolic alterations such as an impairment of oxidative metabolism seem to be responsible for the disability in the chronic phase of the disease. | 23820876 |
| Inflammation | Altered Intercellular Communication | Inflammation may be a common underlying cause or represents a final common pathway. | 23821322 |
| Inflammation, Retinitis Pigmentosa, Uveitis | Altered Intercellular Communication | Clinicians should be aware of various manifestations of RP, including mild inflammation, to avoid possible confusin with uveitis. | 23822599 |
| Inflammation, Fibrosis Assessment, Neoplasms, Vascular Tissue, Necrosis | Altered Intercellular Communication | However, final histology demonstrated fibroadipose tissue with fat necrosis and fibrosis, thickened vascular vessels, and diffuse chronic inflammation with lymphocytic infiltrates, which are more consistent with an atypical inflammatory vascular tumor. | 23823059 |
| Retinitis, diabetic | Altered Intercellular Communication | Recent findings have implicated the involvement of interferon-g (IFN-g), a part of the Th1 cytokine response, in the retinal inflammation of diabetic patients. | 23823918 |
| Hyperglycemia, Inflammation | Altered Intercellular Communication | It is possible that IFN-g production via IL-18 in the retinas of 60-week-old OLETF rats is caused by hyperglycemia, and plays a role in the inflammation of the OLETF rat retinas. | 23823918 |
| Inflammation, polyps | Altered Intercellular Communication | The histopathology showed benign polyp with non-specific inflammation. | 23823964 |
| Inflammation, Juxtapapillary focal retinitis AND retinochoroiditis | Altered Intercellular Communication | Bilateral anterior chamber inflammation was associated with neuroretinitis in the right eye. | 23824660 |
| Autoimmune Diseases, Inflammation, Primary malignant neoplasm, Malignant neoplasm of vulva | Altered Intercellular Communication | The toll-like receptor and the nuclear factor kB (NF-kB) signaling pathways have been implicated in inflammation, autoimmune disease and cancer, but whether common nucleotide variation in these pathways is associated with the risk of cervical and vulvar cancers has received little study. | 23824834 |
| Inflammation, Primary malignant neoplasm, Psychiatric, Depression, CTCAE, Psychological Distress | Altered Intercellular Communication | Studies of the biopsychosocial approach covering the psychological implications of cancer (e.g., prevalence of emotional distress, application of DSM/ICD classical, and more recent psychiatric classification systems), their psychobiological concomitants (e.g., inflammation and immune dysregulation mechanisms in depression and chronobiology of stress and cancer), and interpersonal issues (e.g., doctor-patient communication and role of neuron mirror system) are discussed. | 23825038 |
| Hypothalamic structure | Altered Intercellular Communication | MAP2K3 is associated with body mass index in American Indians and Caucasians and may mediate hypothalamic inflammation. | 23825110 |
| Obesity, Hypothalamic structure | Altered Intercellular Communication | We conclude that MAP2K3 is a reproducible obesity locus that may affect body weight via complex mechanisms involving appetite regulation and hypothalamic inflammation. | 23825110 |
| Inflammation, Primary malignant neoplasm, Cardiovascular Diseases | Altered Intercellular Communication | High blood concentrations of n-6 fatty acids (FAs) relative to n-3 FAs may lead to a "physiological switch" towards permanent low-grade inflammation, potentially influencing the onset of cardiovascular and inflammatory diseases, as well as cancer. | 23825649 |
| Lung hyperinflation, Inflammation | Altered Intercellular Communication | A significant correlation between E/A ratio and PaO2 was observed (r=0.26, p<0.05), but not with static lung hyperinflation, inflammation or right ventricle overload parameters. | 23826360 |
| Nonalcoholic Steatohepatitis, Inflammation, Diabetes Mellitus, Obesity, Liver Cirrhosis | Altered Intercellular Communication | Non-alcoholic steato-hepatitis is more common in the presence of diabetes, obesity, older age and increased inflammation, and is more likely to progress to cirrhosis. | 23826593 |
| Inflammation, Pyoderma | Altered Intercellular Communication | Total Count, ESR and CRP are not specific as they can also be elevated in non pyogenic causes of inflammation. | 23826894 |
| Bronchitis | Altered Intercellular Communication | Bronchial anthracofibrosis is a rare disease characterised by chronic bronchial inflammation, with bronchoscopic findings showing dark anthracotic pigmentation on the bronchial mucosa in conjunction with bronchial narrowing or obliteration which causes stenosis of the airways. | 23827039 |
| Autoimmune Diseases, Inflammation | Altered Intercellular Communication | Th17 cells representing novel subset of CD4(+) cells have well described roles in autoimmune diseases and inflammation. | 23827655 |
| Communicable Diseases, Inflammation, Neoplasms | Altered Intercellular Communication | It is important to closely monitor a G-CSF producing tumor, when a patient shows severe inflammation, but no infection. | 23827867 |
| Inflammation, Osteoarthritis, Knee | Altered Intercellular Communication | Connective tissue growth factor promotes interleukin-1b-mediated synovial inflammation in knee osteoarthritis. | 23827951 |
| Inflammation | Altered Intercellular Communication | VEGF predicts all-cause mortality, independent of inflammation, while an elevated sVEGFR-1 level increased the mortality risk in inflamed patients. | 23828162 |
| Inflammation, Renal function, Chronic Kidney Diseases | Altered Intercellular Communication | Chronic kidney disease (CKD) is characterized by a continuous reduction in kidney function, increased inflammation, and reduced antioxidant capacity. | 23828329 |
| Inflammation | Altered Intercellular Communication | Baseline data demonstrated elevated inflammation and low antioxidant levels. | 23828329 |
| Inflammation, Chronic Kidney Diseases | Altered Intercellular Communication | This study demonstrates that mild and moderate CKD is associated with chronic inflammation and low antioxidant activity. | 23828329 |
| Inflammation, Chronic Kidney Diseases | Altered Intercellular Communication | Systemic inflammation and impaired antioxidant status may be greater in CKD populations with multiple comorbidities. | 23828329 |
| Ischemia, Inflammation, Perforation (observation), Small bowel obstruction, Adenocarcinoma of large intestine | Altered Intercellular Communication | To this end, 56 patients were assigned to the following groups according to their disease: bowel ischaemia (group 1: n = 14), small bowel obstruction (group 2: n = 12), acute inflammation (group 3: n = 6), perforation (group 4: n = 8), and colorectal adenocarcinoma (group 5: n = 16). | 23828592 |
| Cancer-related fatigue, Chronic inflammation | Altered Intercellular Communication | Muscular fitness, cardiorespiratory fitness (CRF) and fatness are mutually related with chronic inflammation. | 23828843 |
| Inflammation | Altered Intercellular Communication | Adolescents with higher levels of muscular fitness present a lower chronic inflammation, and this seems to be explained by lower levels of fatness. | 23828843 |
| Inflammation | Altered Intercellular Communication | Any concentration of secretory leukocyte protease inhibitor (SLPI) indicates the dominant hyperergic inflammation in periodontal tissues, accompanied by increased proteolysis. | 23828974 |
| Inflammation, Hemolysis (biological function) | Altered Intercellular Communication | Acute hemolysis after intravenous immunoglobulin amid host factors of ABO-mismatched bone marrow transplantation, inflammation, and activated mononuclear phagocytes. | 23829192 |
| Inflammation, Hemolysis (lab result) | Altered Intercellular Communication | Synergizing host factors (including obesity-unadjusted dosing and existing inflammation) marked this severe post-IVIG hemolytic crisis. | 23829192 |
| Inflammation | Altered Intercellular Communication | Multi-factorial causes of CSA-AKI involve oxidative stress and inflammation. | 23829828 |
| Inflammation, Cerebral Ischemia | Altered Intercellular Communication | Evidence in human and animal models shows BBB disruption is associated with activation of matrix metalloproteinase-9 (MMP-9) after cerebral ischemia and inflammation. | 23829879 |
| Inflammation | Altered Intercellular Communication | Adipocyte fatty acid-binding protein (A-FABP) plays a key role in obesity-related insulin resistance and inflammation which may be involved in the pathogenesis of sarcopenic obesity (SO). | 23830287 |
| Diabetic Neuropathies | Altered Intercellular Communication | Our study indicates that Munc13-1, on account of its role in both insulin and neurotransmitter exocytosis and through its binding properties, may be an important factor contributing to the development or progression of diabetic neuropathy. | 23830992 |
| Infection | Altered Intercellular Communication | Premature aging can impair lung function by different ways: by interfering specifically with tissue repair mechanisms after damage, thus perturbing the correct crosstalk between mesenchymal and epithelial components; by inducing systemic and/or local alteration of the immune system, thus impairing the complex mechanisms of lung defense against infections; and by stimulating a local and/or systemic inflammatory condition (inflammaging). | 23831269 |
| Infection | Altered Intercellular Communication | Premature aging can impair lung function by different ways: by interfering specifically with tissue repair mechanisms after damage, thus perturbing the correct crosstalk between mesenchymal and epithelial components; by inducing systemic and/or local alteration of the immune system, thus impairing the complex mechanisms of lung defense against infections; and by stimulating a local and/or systemic inflammatory condition (inflammaging). | 23831269 |
| Inflammation, Dental Plaque, physiopathological | Altered Intercellular Communication | Arginase-II (Arg-II) has been shown to promote vascular dysfunction and plaque vulnerability phenotypes in mice through uncoupling of endothelial nitric oxide synthase and activation of macrophage inflammation. | 23832324 |
| Oophoritis | Altered Intercellular Communication | Xanthomatous oophoritis is a rare inflammatory condition of the ovaries. | 23833001 |
| Airway structure, Airway Obstruction | Altered Intercellular Communication | Both are characterized by heterogeneous chronic airway inflammation and airway obstruction. | 23833163 |
| Inflammation, Calcinosis | Altered Intercellular Communication | Focal arterial inflammation precedes subsequent calcification in the same location: a longitudinal FDG-PET/CT study. | 23833282 |
| vascular inflammations | Altered Intercellular Communication | We sought to test the hypothesis that local vascular inflammation predisposes to subsequent arterial calcium deposition in humans. | 23833282 |
| Inflammation, Dental Plaque | Altered Intercellular Communication | Here, we provide first-in-man evidence that arterial inflammation precedes subsequent Ca deposition, a marker of plaque progression, within the underlying location in the artery wall. | 23833282 |
| Airway structure, Exacerbation | Altered Intercellular Communication | COPD exacerbations are associated with neutrophilic airway inflammation. | 23834268 |
| Inflammation, Hypertensive (finding) | Altered Intercellular Communication | Relationships of different blood pressure categories to indices of inflammation and platelet activity in sustained hypertensive patients with uncontrolled office blood pressure. | 23834704 |
| Inflammation, Hypertensive (finding) | Altered Intercellular Communication | In conclusion, in hypertensive patients with uncontrolled office BP, presence of non-dipping BP is associated with increased platelet activity and inflammation, which can be one of the underlying plausible mechanisms of non-dipping BP status. | 23834704 |
| Inflammation, Lower respiratory tract infection, Respiratory Tract Infections, Acute onset cough | Altered Intercellular Communication | Point-of-care C-reactive protein (POCCRP) is a biomarker of inflammation that offers clinicians a rapid POC test to guide antibiotic prescribing decisions for acute cough and lower respiratory tract infections (LRTI). | 23834883 |
| Inflammation, Neoplasms | Altered Intercellular Communication | Elevated FAP-a expression may be associated with inflammation and suppressed lymphocyte-dependent immune response, which then result in the tumor progression. | 23835897 |
| Coughing, Gastroesophageal reflux disease, Airway structure | Altered Intercellular Communication | We conclude that cough accompanying GERD is unlikely to be associated with the presence of co-morbid asthma, but rather suggests a mild airway inflammation developing as a sequel of GERD. | 23835974 |
| Autoimmune Diseases, Granulomatous inflammation, Pulmonary vascular system, Vasculitis, CTCAE | Altered Intercellular Communication | Pulmonary vasculitis is a potentially lethal autoimmune disease characterized by granulomatous inflammation of respiratory tract, necrotizing vasculitis affecting small-to medium-size vessels and antineutrophil cytoplasmic antibodies elevation. | 23835997 |
| Specimen Type - Fistula, Pelvic Inflammatory Disease | Altered Intercellular Communication | This simple treatment produced a cure of the pelvic inflammation and closure of the fistula without compromising a more aggressive secondary treatment which was not necessary in our series. | 23836114 |
| Inflammation, Schizophrenia | Altered Intercellular Communication | Inflammation and schizophrenia: alterations in cytokine levels and perturbation in antioxidative defense systems. | 23836841 |
| Inflammation, Schizophrenia | Altered Intercellular Communication | A relationship between inflammation and schizophrenia has been supported by abnormal cytokine production and altered antioxidant status. | 23836841 |
| Inflammation, Schizophrenia | Altered Intercellular Communication | We conclude that inflammation resulting from dysregulation of cytokines and altered antioxidant systems may play a critical role in the etiology of schizophrenia. | 23836841 |
| Schizophrenia, Virus Diseases, Abnormal synaptic transmission, Immune System Diseases | Altered Intercellular Communication | Although several theories have been proposed including developmental/neurodegenerative processes, neurotransmitter abnormalities, viral infection, and immune dysfunction, the exact causative factor of schizophrenia is unclear. | 23836841 |
| Inflammation | Altered Intercellular Communication | Fragmented cytokeratin-18 (CK-18) levels were positively correlated with NAS (r=0.401), as well as NAS components such as lobular inflammation (r=0.387) and ballooning (r=0.231). | 23837136 |
| Inflammation, Endothelial dysfunction, Diabetic Retinopathy | Altered Intercellular Communication | The role of inflammation and endothelial dysfunction in the pathogenesis of diabetic retinopathy. | 23837221 |
| Diabetic Retinopathy, Inflammation, Endothelial dysfunction, GDC Disease Response Terminology | Altered Intercellular Communication | The pathogenesis of diabetic retinopathy (DR) is insufficiently understood and presumed to possibly involve inflammation and endothelial dysfunction. | 23837221 |
| Inflammation, Endothelial dysfunction | Altered Intercellular Communication | The groups did not differ in the levels of inflammation markers, other markers of endothelial dysfunction and anthropometric parameters. | 23837221 |
| Inflammation, Obesity, GDC Disease Response Terminology | Altered Intercellular Communication | The study demonstrated that the association between obesity, inflammation and other risk factors plays an important role in endothelial impairment involved in the pathogenesis of DR. | 23837221 |
| Inflammation, Liver Stiffness | Altered Intercellular Communication | Multivariate analysis revealed no correlation between the grade of histologic inflammation and liver stiffness measured by magnetic resonance elastography (R2 = 0.265, p = 0.47). | 23837611 |
| Inflammation, Depression, CTCAE | Altered Intercellular Communication | These results are consistent with previous findings in this cohort for systemic inflammation, blood pressure, and ST segment depression. | 23838152 |
| Inflammation, Gland, Colitis | Altered Intercellular Communication | A surgical biopsy showed chronic colitis with inflammation extending to the muscularis mucosae, with areas of glandular atrophy. | 23838945 |
| ARCN1 gene, Inflammation | Altered Intercellular Communication | The MPR, which was independently associated with systemic inflammation and airflow limitation, was impaired in patients with COPD. | 23839654 |
| Pain Distress Question, Inflammation | Altered Intercellular Communication | In patients with CP, with opiate-dependent abdominal pain, circulating cytokine levels are low suggesting that pain in this disease is not simply a manifestation of inflammation. | 23840145 |
| Cystadenoma, Mucinous, Carcinoid Tumor, Granulomatous inflammation, Adenocarcinoma, Fibrous, Diverticulum, Adult Non-Hodgkin Lymphoma, Adenomatous Polyps | Altered Intercellular Communication | The unusual histopathological findings included fibrous obliteration (n = 62), enterobius vermicularis (n = 31), eosinophilic infiltration (n = 10), mucinous cystadenoma (n = 8), carcinoid tumor (n = 6), granulomatous inflammation (n = 5), adenocarcinoma (n = 4; one of them mucinous), and mucocele (n = 3), adenomatous polyp (n = 1), taenia sup (n = 1), ascaris lumbricoides (n = 1), appendiceal diverticula (n = 1), and B cell non-hodgkin lymphoma (n = 1). | 23840147 |
| Communicable Diseases, Neurologic Deficits, Inflammation, Trauma, Nervous System | Altered Intercellular Communication | Shortly after infection, HIV enters the brain and causes widespread inflammation and neuronal damage, which ultimately leads to neuropsychological impairments. | 23840428 |
| methyldopa, Inflammation | Altered Intercellular Communication | This paper outlines the importance of association between inflammation and AMD. | 23840568 |
| methyldopa, Inflammation | Altered Intercellular Communication | This provides further evidence for the link between A2E, inflammation, and the pathogenesis of AMD. | 23840644 |
| ARCN1 gene, Chronic Obstructive Airway Disease, Pneumonitis | Altered Intercellular Communication | In chronic obstructive pulmonary disease (COPD), primarily caused by cigarette smoke (CS), lung inflammation persists and smooth muscle tone remains elevated, despite ample amounts of nitric oxide that could activate sGC. | 23841447 |
| Vasculitis, Leukocytoclastic, Cutaneous, Inflammation, Neutrophilic dermatosis, Senile purpura | Altered Intercellular Communication | We studied 95 cases diagnosed as solar purpura and identified 10 cases (10.5%) in which significant neutrophilic inflammation was present, potentially simulating a leukocytoclastic vasculitis or neutrophilic dermatosis. | 23842046 |
| Inflammation, Damage | Altered Intercellular Communication | The classifier consists of 17 peptides derived from albumin, b2-microglobulin, CD99, fibronectin and various collagen a-chains, indicating inflammation, activation of T cells and changes in the extracellular matrix as early signs of GvHD-induced organ damage. | 23842427 |
| Inflammation, Obesity | Altered Intercellular Communication | Chronic inflammation, which is associated with obesity, may play a role in the etiology of several diseases. | 23844105 |
| Inflammation | Altered Intercellular Communication | These results suggest that posited anti-inflammatory drugs and behaviors may be less strongly associated with inflammation among the obese than among lower weight persons. | 23844105 |
| Data types - Address | Altered Intercellular Communication | Inflammation clearly occurs in pathologically vulnerable regions of the AD brain, with increased expression of acute phase proteins and pro-inflammatory cytokines. | 23844688 |
| ARCN1 gene, Inflammation | Altered Intercellular Communication | Because pathogenesis, disease activity and disease progression in COPD are believed to be partly dependent of neutrophil driven inflammation we decided to investigate whether plasma level of calprotectin (p-calprotectin) was associated with all-cause mortality in patients with COPD. | 23844942 |
| Hemospermia, Inflammation, Prostate | Altered Intercellular Communication | Hematospermia is usually caused by nonspecific inflammation of the prostate and seminal vesicles. | 23845256 |
| Inflammation, Traumatic injury | Altered Intercellular Communication | The initiating factor in internal root resorption is thought to be trauma or chronic pulpal inflammation, but other aetiological factors have also been suggested. | 23845670 |
| Inflammation, immunoglobulin A, Epithelial cyst | Altered Intercellular Communication | Histopathological examination showed immunoreactivity to IgA on the luminal surface of the epithelial ductal cyst and mild chronic inflammation in the underlying stroma or lacrimal gland. | 23846204 |
| Inflammation | Altered Intercellular Communication | Our results suggest that a multifactorial mechanism leads to dacryops including chronic inflammation, an immune response, and IgA hypersecretion with an osmotic effect, all contributing to the cyst formation. | 23846204 |
| Tissue damage, Inflammation | Altered Intercellular Communication | p.R482W-prelamin-A also induced oxidative stress, DNA damages, and inflammation. | 23846499 |
| Inflammation, Benign prostatic hypertrophy | Altered Intercellular Communication | Lipidosterolic extract of serenoa repens modulates the expression of inflammation related-genes in benign prostatic hyperplasia epithelial and stromal cells. | 23846725 |
| Inflammation | Altered Intercellular Communication | These results suggest that LSESr may be useful to treat BPH that manifest inflammation characteristics. | 23846725 |
| Inflammation | Altered Intercellular Communication | This also supports a role for inflammation in BPH presumably by mediating the balance between apoptosis and proliferation. | 23846725 |
| Inflammation, Dyslipidemias, Lower Urinary Tract Symptoms | Altered Intercellular Communication | Dyslipidemia and chronic inflammation may play a role in the cause of lower urinary tract symptoms (LUTS) in older men. | 23847173 |
| Cardiac Hypertrophy, Inflammation | Altered Intercellular Communication | And also to explore the correlation of cardiac hypertrophy and inflammation. | 23847952 |
| Inflammation, Anemia, Chronic Kidney Diseases, Diabetes Mellitus | Altered Intercellular Communication | Our results also determined MCV as an independent predictor of composite CV events independent of anaemia, inflammation, diabetes and eGFR in patients with CKD. | 23848392 |
| Inflammation, Atherosclerosis | Altered Intercellular Communication | Inflammation is present in every stage of the atherosclerosis process, therefore, inflammation hallmarks such as the fibrinogen can be related to the complications in which it intervenes, mortality is one of them. | 23849212 |
| Human papilloma virus infection, Sex Behavior, Uterine Cervicitis | Altered Intercellular Communication | HPV infection was associated with age, sexual behavior and chronic inflammation of the cervix and vagina. | 23849649 |
| Cataract, Inflammatory abnormality of the eye | Altered Intercellular Communication | To determine whether postoperative ocular inflammation is less after femtosecond laser-assisted cataract surgery than after conventional phacoemulsification (manual) cataract surgery. | 23850229 |
| Cataract, Inflammation | Altered Intercellular Communication | Anterior segment inflammation was less after femtosecond laser-assisted cataract surgery than after manual cataract surgery, and this appeared to be due to a reduction in phacoemulsification energy. | 23850229 |
| Inflammation | Altered Intercellular Communication | In 50 knees, 90% of capsular sites were involved by inflammation in comparison with 23% of intracapsular sites and 4.7% of extracapsular sites (P < 0.0001). | 23850896 |
| Pancreatitis, Acute, Inflammation, Pancreatitis, Cardiovascular Diseases | Altered Intercellular Communication | The low-grade inflammation that characterizes cardiovascular disorders may facilitate the development of pancreatitis; therefore, we investigated the connection between cardiovascular disorders and acute pancreatitis. | 23851434 |
| Hyperplasia, Traumatic injury | Altered Intercellular Communication | The etiology and pathogenesis of condylar hyperplasia remain uncertain, but it has been suggested that its etiology may be associated with hormonal factors, trauma, and hereditary hypervascularity, affecting both genders. | 23851829 |
| Inflammation | Altered Intercellular Communication | Apoptosis plays a critical role in the regulation of inflammation and host immune response which helps in tissue homeostasis, and a disturbance in this is often associated with disease. | 23852253 |
| Fibrosis Assessment, Hepatic inflammation | Altered Intercellular Communication | Taken together, decreased 25(OH)D and increased ferritin serum levels indicate the severity of hepatic inflammation and fibrosis in patients infected chronically with HCV type 1. | 23852677 |
| muscle fibrosis, Inflammation, Edema | Altered Intercellular Communication | Magnetic resonance imaging (MRI) revealed muscle fibrosis in directly injected muscles, whereas in subcutaneous fat and within muscles of anterior and posterior compartments of both thighs, not directly injected, there were signal changes supportive of oedema and inflammation. | 23853507 |
| ARCN1 gene, Inflammation | Altered Intercellular Communication | Chronic inflammation and changes to the lung extracellular matrix (ECM) have been implicated in the pathogenesis of COPD, yet the mechanisms that lead to PH secondary to COPD remain unknown. | 23855769 |
| Inflammation, Metabolic Diseases, Depression, CTCAE | Altered Intercellular Communication | There is evidence that depression is accompanied by inflammation, oxidative and nitrosative stress (O&NS) and metabolic disorders. | 23856278 |
| Inflammation, Metabolic Diseases, Suicide | Altered Intercellular Communication | This study examines whether a history of suicide attempts is associated with inflammation, O&NS and metabolic disorders. | 23856278 |
| Inflammation, Fever | Altered Intercellular Communication | All had signs of local inflammation, three showed locoregional inflammation, three were febrile. | 23856550 |
| Communicable Diseases, Inflammation, Lymphadenopathy | Altered Intercellular Communication | In all cases, there was no sign of local inflammation, regional lymphadenopathy or systemic infection at the last follow-up. | 23856550 |
| Inflammation, Chagas Disease | Altered Intercellular Communication | While MMP-9 seems to be involved in the inflammation and cardiac remodeling of Chagas disease, MMP-2 does not correlate with inflammatory molecules. | 23856618 |
| Inflammation, atherosclerotic | Altered Intercellular Communication | However, inflammation due to overproduction of IL-6 persisted, and atherosclerotic vascular events occurred as critical complications, even though the serum levels of lipids were very low. | 23857095 |
| ARCN1 gene, Inflammation, Respiration Disorders, Simultaneous | Altered Intercellular Communication | Monitoring inflammation in the upper airways can be a useful tool for evaluating respiratory diseases in the elderly and in those with concomitant asthma and COPD, a clinical entity not yet fully understood. | 23857681 |
| Inflammation, Fracture | Altered Intercellular Communication | Epidemiological studies have shown low-grade inflammation measured by high-sensitivity C-reactive protein (hs-CRP) to be associated with fracture risk in women. | 23857741 |
| Inflammation, Impaired cognition | Altered Intercellular Communication | A significant rise in CRP concentrations over 12 months, but lack of significant association with cognition, provide no evidence for a relationship between systemic inflammation and cognitive decline in amnestic MCI. | 23857873 |
| Kidney Failure, Chronic, Inflammation, Malnutrition, Cardiac dysfunction | Altered Intercellular Communication | Little is known about the impact of low triiodothyronine (T3) levels on mortality in end-stage renal disease (ESRD) patients starting hemodialysis (HD) and whether this impact is mediated by malnutrition, inflammation, or cardiac dysfunction. | 23857979 |
| Inflammation, Colorectal Carcinoma | Altered Intercellular Communication | These data suggest that dietary factors involved in inflammation and oxidative stress interact with MAPK-signaling genes to alter risk of colorectal cancer. | 23859041 |
| Inflammation, Thrombosis, Pulmonary Embolism, Pneumonia, Pulmonary Emphysema | Altered Intercellular Communication | Of the CT findings on day 5, pneumonia, pulmonary embolism, portal or mesenteric thrombosis, operative area fat infiltration, peritoneal effusion, pneumoperitoneum, intra-abdominal collection, parietal inflammation or collection, and subcutaneous emphysema were observed in both groups without any significant difference. | 23860629 |
| Inflammation, hepcidin | Altered Intercellular Communication | Ferroportin in monocytes of hemodialysis patients and its associations with hepcidin, inflammation, markers of iron status and resistance to erythropoietin. | 23860963 |
| HD Term Type, Inflammation, hepcidin | Altered Intercellular Communication | Decreased ferroportin in monocytes of HD patients accompanies increased hepcidin, inflammation, decreased iron availability and is correlated with resistance to rHuEpo treatment. | 23860963 |
| Inflammation, Edema | Altered Intercellular Communication | Serum amyloid A as a major protein involved in the acute and chronic stages of inflammation, and IL-6 and bFGF were significantly associated with the extent of macular edema in patients with RVO. | 23861862 |
| Inflammation | Altered Intercellular Communication | Wine- or magenta-colored colloid and inflammation were found in one or both sides of the seminal vesicle in all the cases. | 23862232 |
| Hepatitis B, Hepatitis C, Hepatitis | Altered Intercellular Communication | To investigate the relationship between hepatitis B virus (HBV) genotypes and hepatitis B early antigen (HBeAg) as well as the hepatitis C antibody, alanine aminotransferase (ALT) levels and liver inflammation and damage in chronic patients of hepatitis B. | 23862244 |
| Fibrosis Assessment, Hepatic inflammation | Altered Intercellular Communication | The degree of hepatic inflammation, fibrosis stage and alanine aminotransferase levels were similar in both the groups (p > 0.05). | 23862244 |
| Granuloma, Granulomatosis, Non-necrotizing granulomatous inflammation, Swelling, Vulva | Altered Intercellular Communication | Ano-genital granulomatosis is a rare chronic inflammatory condition and that can present as diffuse penile, scrotal, vulvar or ano-perineal swelling with non-caseating non-necrotising granulomas on histology. | 23862402 |
| Inflammation, Atherosclerosis, Cerebrovascular accident | Altered Intercellular Communication | Phosphodiesterase 4D (PDE4D), through the regulation of cyclic AMP, modulates inflammation and other processes that affect atherosclerosis and stroke. | 23863764 |
| Inflammation | Altered Intercellular Communication | This PDE4D genotype may lead to accelerated cyclic AMP degradation and subsequently elevated inflammation 1 day after CEA. | 23863764 |
| Inflammation, Primary malignant neoplasm, Obesity | Altered Intercellular Communication | Their dysfunctions are associated with aging, cancer, obesity, and inflammation. | 23863811 |
| Refractory anemias, Rheumatoid Arthritis, Inflammation | Altered Intercellular Communication | Several lines of evidence suggest the involvement of NPY in the regulation of rheumatoid arthritis (RA), and VIP has already been identified as a potent anti-inflammatory factor that reduces joint inflammation. | 23864142 |
| Inflammation, Necrosis | Altered Intercellular Communication | The muscle histology demonstrated pronounced acute inflammation and limited necrosis of muscle fibers confined to the right gluteal muscles. | 23864208 |
| Liver carcinoma, Complete atrioventricular block, Malignant Neoplasms, FAM126A gene, Hepatitis B, Chronic | Altered Intercellular Communication | Hepatocellular carcinoma (HCC) is an inflammation-related malignancy and chronic hepatitis B (CHB) predisposes to HCC. | 23864279 |
| Pancreatitis | Altered Intercellular Communication | Acute pancreatitis is well defined as pancreatic inflammation due to the activation of pancreatic enzymes secondary to several etiological factors. | 23864450 |
| Inflammation, Infection caused by Helicobacter pylori | Altered Intercellular Communication | The pathology showed moderate chronic inflammation and erosion of the gastric body mucosa, with accompanying Helicobacter pylori infection. | 23864452 |
| Inflammation, Amyloidosis, Infection caused by Helicobacter pylori | Altered Intercellular Communication | The pathology showed chronic mild-moderate inflammation of the gastric body mucosa associated with interstitial amyloidosis, with accompanying Helicobacter pylori infection. | 23864452 |
| Benign Prostatic Hyperplasia, Inflammation, Prostatic Diseases, Prostate carcinoma, Prostate | Altered Intercellular Communication | Close links have been noted between chronic inflammation of the prostate and the development of human prostatic diseases such as benign prostate hyperplasia (BPH) and prostate cancer. | 23864729 |
| prostatitis | Altered Intercellular Communication | However, the molecular mechanisms that contribute to prostatic inflammation remain largely unexplored. | 23864729 |
| Inflammation, Prostate carcinoma, Prostatic Diseases, Prostatic Infection | Altered Intercellular Communication | Given that human prostatic infections are associated with chronic inflammation, the development of BPH is associated with an accumulation of senescent cells with a proinflammatory phenotype, and the development of prostate cancer is associated with the loss of IFN signaling, the role of AIM2 in mediating the formation of prostatic diseases was investigated. | 23864729 |
| Traumatic injury | Altered Intercellular Communication | Inflammation represents the immune system response to external or internal aggressors such as injury or infection in certain tissues. | 23864770 |
| Inflammation, Primary malignant neoplasm, Neoplasms | Altered Intercellular Communication | The body's response to cancer has many parallels with inflammation and repair; the inflammatory cells and cytokines present in tumours are more likely to contribute to tumour growth, progression, and immunosuppression, rather than in building an effective antitumour defence. | 23864770 |
| Inflammation, Dysplasia, Malignant Neoplasms, Thrombopoietin Receptor Agonist LGD-4665, Atrophic, HGD gene | Altered Intercellular Communication | Histopathology revealed 10 inflammation, 14 atrophy, 10 metaplasia, 1 low grade dysplasia (LGD), 5 high grade dysplasia (HGD) and 3 cancers. | 23864787 |
| Inflammation, Fibrosis Assessment, Transplant glomerulopathy | Altered Intercellular Communication | Compared to no-AR, all histologic types of AR led to abnormal histology in 1 and 2 years protocol biopsies, including more fibrosis + inflammation (6.3% vs. 21.9%), moderate/severe fibrosis (7.7% vs. 13.5%) and transplant glomerulopathy (1.4% vs. 8.3%, all p < 0.0001). | 23865852 |
| Inflammation | Altered Intercellular Communication | In DSA negative recipients, early AR often leads to persistent graft inflammation and increases the risk of new DSA II production. | 23865852 |
| Inflammation, Gilbert Disease (disorder) | Altered Intercellular Communication | Haem catabolism: a novel modulator of inflammation in Gilbert's syndrome. | 23865893 |
| Inflammation, Gilbert Disease (disorder), Noncommunicable Diseases | Altered Intercellular Communication | Furthermore, reduced body mass index in Gilbert's syndrome individuals was linked to reduced inflammation status, which could be influenced by circulating haem oxygenase catabolites and contribute to reduced risk of noncommunicable diseases in this population. | 23865893 |
| Inflammation, Meckel Diverticulum, Peutz-Jeghers Syndrome, Disorder of small intestine, Crohn Disease, Henoch-Schoenlein Purpura | Altered Intercellular Communication | Of the 70 children, 58 (83%) had small bowel disease according to the single-balloon enteroscopy results, including 24 cases of non-specific inflammation, 12 cases of allergic purpura, 8 cases of Crohn's disease, 8 cases of Meckel's diverticulum, and 6 cases of Peutz-Jeghers syndrome. | 23866276 |
| Cataract, Inflammation, Uveitis | Altered Intercellular Communication | [Clinical research of anterior chamber inflammation after phacoemulsification surgery in patients with complicated cataract secondary to uveitis]. | 23866701 |
| Inflammation, Uveomeningoencephalitic Syndrome, Behcet Syndrome | Altered Intercellular Communication | To investigate anterior chamber inflammation after phacoemulsification with intraocular lens (IOL) implantation in patients with Vogt-Koyanagi-Harada (VKH) syndrome or Behcet's disease (BD). | 23866701 |
| Inflammation, Uveomeningoencephalitic Syndrome | Altered Intercellular Communication | Anterior chamber inflammation reaches peak levels one week postoperatively in VKH and BD patients who receive phacoemulsification with IOL implantation. | 23866701 |
| Inflammation, Infectious Lung Disorder, Septic Shock | Altered Intercellular Communication | Pulmonary infection, and not systemic inflammation, accounts for increased concentrations of exhaled nitric oxide in patients with septic shock. | 23867579 |
| Inflammation, respiratory, Infectious Lung Disorder | Altered Intercellular Communication | To assess whether a pulmonary infection itself or systemic inflammation is responsible for NO production, we determined exhaled NO in ventilated patients with respiratory and non-respiratory septic shock and compared it with the concentration in ventilated intensive care patients without systemic inflammation. | 23867579 |
| Inflammation | Altered Intercellular Communication | The controls without systemic inflammation, as witnessed by the absence of systemic inflammatory response syndrome criteria and low levels of interleukin-6, had similar concentrations of NO as the patients with non-respiratory septic shock. | 23867579 |
| Inflammation | Altered Intercellular Communication | This can be a non-inflammatory process, but it may also result from chronic inflammation occurring in the suprachoroidal space. | 23867717 |
| Inflammation, Sleep Apnea, Obstructive | Altered Intercellular Communication | Inflammation plays a critical role in the pathogenesis of obstructive sleep apnea syndrome (OSAS). | 23868710 |
| Inflammation, Fibrosis Assessment | Altered Intercellular Communication | Within abnormal distal ileal segments, the mean contrast enhancement ratio of acute inflammation was 2.39 +- 0.59 compared with 1.82 +- 0.63 (P < 0.05) in segments with fibrosis only. | 23869486 |
| Inflammation, Hypertriglyceridemia, Endothelial dysfunction | Altered Intercellular Communication | Several authors have reported the association of postprandial hypertriglyceridemia with oxidative stress, systemic inflammation and endothelial dysfunction. | 23869888 |
| Inflammation, Hypersensitivity | Altered Intercellular Communication | Orbital inflammation secondary to a delayed hypersensitivity reaction to sub-Tenon's hyaluronidase. | 23869964 |
| Orbital Pseudotumor, Allergy - Charge Type Reason | Altered Intercellular Communication | We report a rare case of a delayed orbital inflammation with raised intraocular pressure as a result of hyluronidase allergy following sub-Tenon's anaesthesia. | 23869964 |
| Allergic, Orbital Pseudotumor | Altered Intercellular Communication | Here, we have shown evidence to prove the orbital inflammation to be an allergic response to hyluronidase with a skin patch test. | 23869964 |
| Allergic, Allergy - Charge Type Reason | Altered Intercellular Communication | This case demonstrates hyaluronidase allergy should be considered as a differential diagnosis among patients presenting with acute post-operative orbital inflammation, even if there is a history of previous exposure to hyaluronidase in the fellow eye with no subsequent allergic response. | 23869964 |
| Communicable Diseases, Tumor necrosis, Inflammation | Altered Intercellular Communication | Tumor necrosis factor alpha (TNF-a) plays an important role in inflammation, immunity, and defense against infection and clearance of human papillomavirus (HPV). | 23870134 |
| Acute Lung Injury, Inflammation, Multiple Organ Failure | Altered Intercellular Communication | Heparin-binding protein is released by neutrophils during inflammation and disrupts the integrity of the alveolar and capillary endothelial barrier implicated in the development of acute lung injury and systemic organ failure. | 23870614 |
| Alzheimers Disease", Inflammation | Altered Intercellular Communication | Alzheimer's disease treated patients showed different patterns for oxidative stress and inflammation markers. | 23871825 |
| Airway structure | Altered Intercellular Communication | Chronic airway inflammation can be mediated by an enhanced neutrophil oxidative burst. | 23872721 |
| Inflammation, Colonization | Altered Intercellular Communication | A markedly increased ROS production in sputum neutrophils during bacterial AECOPD shows an inflammatory response reflecting enhanced local inflammation, which can be mediated by bacterial colonization. | 23872721 |
| Inflammation, Chronic disease | Altered Intercellular Communication | Handgrip strength (HGS) has been shown to predict survival and is associated with changes in body composition, nutritional status, inflammation, and functional ability in several chronic disease conditions. | 23872952 |
| Communicable Diseases, Inflammation | Altered Intercellular Communication | Signs of infection and inflammation mostly resolved within 1 to 2 weeks after the treatment. | 23873492 |
| Inflammation, Thrombosis | Altered Intercellular Communication | Because of the critical role of neutrophils in inflammation associated thrombosis, we asked whether neutrophil tissue factor (TF) may be implicated in the thrombotic diathesis in AAV. | 23873874 |
| Inflammation, Thrombosis, Tissue Factor | Altered Intercellular Communication | Expression of TF in NETs and neutrophil derived MPs proposes a novel mechanism for the induction of thrombosis and inflammation in active AAV. | 23873874 |
| Sample Size Calculation, vascular inflammations | Altered Intercellular Communication | Global chemokine expression in systemic sclerosis (SSc): CCL19 expression correlates with vascular inflammation in SSc skin. | 23873879 |
| Sample Size Calculation, vascular inflammations | Altered Intercellular Communication | To characterise global chemokine expression in systemic sclerosis (SSc) skin in order to better understand the relationship between chemokine expression and vascular inflammation in this disease. | 23873879 |
| vascular inflammations | Altered Intercellular Communication | We tested correlations between the most regulated chemokines and vascular inflammation and macrophage recruitment. | 23873879 |
| vascular inflammations | Altered Intercellular Communication | Expression of CCL19 in dcSSc skin correlated with markers of vascular inflammation and macrophage recruitment. | 23873879 |
| Inflammation | Altered Intercellular Communication | Induction of CCL19 in macrophages but not structural cells indicates a role for skin-resident or recruited immune cells in perivascular inflammation. | 23873879 |
| Inflammation | Altered Intercellular Communication | This study demonstrates that CCL19 is a sensitive marker for the perivascular inflammation and immune cell recruitment seen in dcSSc skin disease. | 23873879 |
| Inflammation, Fibrosis Assessment | Altered Intercellular Communication | Pathological evaluation revealed chronic inflammation of the bronchial mucosa, submucosal carbon particle deposition, and mucosal or submucosal fibrosis. | 23876887 |
| Orthodontic, Inflammation, Dental Plaque | Altered Intercellular Communication | Plaque control is the major consensus during orthodontic treatment to prevent the occurrence of cavities and periodontal inflammation. | 23876953 |
| Granulomatosis with polyangiitis, Glomerulonephritis, Vasculitis, CTCAE | Altered Intercellular Communication | Wegener's granulomatosis or granulomatosis polyangiitis associated (GPA) is a granulomatous inflammation of the upper and lower respiratory tracts associated with necrotising vasculitis of small and medium-sized blood vessels and, frequently, necrotising glomerulonephritis. | 23877415 |
| Inflammatory Bowel Diseases, Inflammation, Defecation | Altered Intercellular Communication | Functional bowel symptoms in quiescent inflammatory bowel diseases: role of epithelial barrier disruption and low-grade inflammation. | 23878165 |
| Inflammatory Bowel Diseases, Inflammation, Irritable Bowel Syndrome | Altered Intercellular Communication | To determine the role of colonic barrier defects and low-grade inflammation in irritable bowel syndrome (IBS)-like symptoms in quiescent inflammatory bowel disease (IBD). | 23878165 |
| Inflammatory Bowel Diseases, Inflammation | Altered Intercellular Communication | In quiescent IBD, IBS-like symptoms related to persistent subclinical inflammation associated with increased colonic paracellular permeability. | 23878165 |
| Inflammation, Hemorrhage | Altered Intercellular Communication | Thought to represent a reparative response to intrabony haemorrhage and inflammation, CGCG was once regarded as a reactive lesion. | 23878288 |
| Inflammation, Hepatitis A, Stomatitis, Cheilitis, Glossitis | Altered Intercellular Communication | Hepatitis A is known to be associated with inflammation of oral mucosa with stomatitis occurring in 78.5% of the patients, glossitis in 71.4%, cheilitis in 64.3%, marginal periodontal inflammation in 85.7%. | 23879055 |
| Inflammation | Altered Intercellular Communication | Genetic polymorphisms related to inflammation and lipid metabolism warrant further investigation for their associations with DKD. | 23879411 |
| Increased insulin level, Inflammation, Hyperglycemia, Diabetes Mellitus | Altered Intercellular Communication | The mechanisms through which diabetes is assumed to promote oncogenesis include insulin resistance and associated hyperinsulinemia, hyperglycemia, and inflammation. | 23879470 |
| Inflammation | Altered Intercellular Communication | The relative contribution of the local vs. peripheral inflammation to the atherothrombotic processes is unknown. | 23880185 |
| Airway structure | Altered Intercellular Communication | Early studies suggested that this might be explained by the presence of heterogeneous airway inflammation. | 23880612 |
| Inflammation, Malnutrition | Altered Intercellular Communication | Adiponectin as a novel indicator of malnutrition and inflammation in hemodialysis patients. | 23880808 |
| Inflammation, Protein-Energy Malnutrition | Altered Intercellular Communication | Protein-energy malnutrition and inflammation are common and overlapping conditions in hemodialysis patients, which are associated with increased risk of morbidity and mortality. | 23880808 |
| Inflammation, Choroidal Neovascularization, Exudate | Altered Intercellular Communication | Probably, vitreomacular adhesion alone is not able to induce age-related macular degeneration, but it may be associated with choroidal neovascularization development, it can contribute to exudate formation and choroidal neovascularization, it may induces or sustains a chronic low-grade inflammation in the macula region. | 23882735 |
| Inflammation, Have Shortness of Breath question, Wheezing, Bronchial Hyperreactivity | Altered Intercellular Communication | Asthma is a chronic multifactorial condition racterized by inflammation, bronchial hyperresponsiveness, narrowing of airway associated with wheezing and shortness of breath, where trials have evidenced that approximately 50% despite being on adequate treatment don't achieve optimal control. | 23882969 |
| Refractory anemias, Rheumatoid Arthritis, Arthritis | Altered Intercellular Communication | Rheumatoid arthritis (RA) is a complex disease, the hallmark of which is synovial joint inflammation. | 23883198 |
| Communicable Diseases, Inflammation, Pseudoaneurysm, Traumatic injury | Altered Intercellular Communication | Disruption of arterial wall integrity as a result of trauma, iatrogeny, inflammation, or infection may result in pseudoaneurysm formation. | 23883787 |
| ARCN1 gene, Inflammation, Chronic Obstructive Airway Disease | Altered Intercellular Communication | Sinonasal inflammation and symptoms are often underdiagnosed in chronic obstructive pulmonary disease (COPD) patients. | 23883807 |
| Inflammation, Obesity | Altered Intercellular Communication | Assessment of iron deficiency in the context of the obesity epidemic: importance of correcting serum ferritin concentrations for inflammation. | 23885047 |
| Inflammation, Overweight | Altered Intercellular Communication | Inflammation (42.3%) was strongly linked with adiposity (20.1%, 37.6%, and 68.4% in normal, overweight, and obese subjects, respectively; P < 0.0001). | 23885047 |
| Ulcerative Colitis, Inflammatory disease of mucous membrane | Altered Intercellular Communication | The colonic mucosal miRNA transcriptome differs significantly between UC and controls, UC and CD, as well as between UC patients with mucosal inflammation and those without. | 23885139 |
| Inflammation, Intestinal Obstruction | Altered Intercellular Communication | In magnetic resonance imaging-Sellink, strong inflammation and intestinal obstruction of the terminal ileum were found. | 23885155 |
| Orbital Pseudotumor | Altered Intercellular Communication | Very mild infiltration was seen around the Left ophthalmic vein, with no other signs of orbital inflammation. | 23885454 |
| Peritonsillar Abscess, Acute suppurative inflammation | Altered Intercellular Communication | Fifty three of them suffered acute suppurative inflammation in the parapharyngeal region that developed as a result of paratonsillar abscess. | 23887371 |
| Inflammation | Altered Intercellular Communication | Endothelin (ET)-1 plays a role in vascular reactive oxygen species production and inflammation. | 23887640 |
| APP gene, Inflammation, Atherosclerosis | Altered Intercellular Communication | ET-1-induced reactive oxygen species and inflammation may contribute to atherosclerosis progression and AAA development. | 23887640 |
| Pterygium Of Conjunctiva And Cornea, Conjunctivitis | Altered Intercellular Communication | Main outcome measures included presence of conjunctival inflammation at 1 month postoperatively as well as recurrence of pterygium. | 23887766 |
| Conjunctivitis | Altered Intercellular Communication | At 1 month postoperatively, different grades of conjunctival inflammation were present in 11 (47.8%) of the steroid group and in 14 (56%) of the control group (P=0.39). | 23887766 |
| Pterygium Of Conjunctiva And Cornea, Conjunctivitis | Altered Intercellular Communication | In pterygium surgery with a bare-sclera technique and mitomycin C application, intraoperative triamcinolone injection did not significantly reduce postoperative conjunctival inflammation or pterygium recurrence. | 23887766 |
| Inflammation, Cerebral Aneurysm, Rupture | Altered Intercellular Communication | Inflammation may play an important role in the formation and rupture of cerebral aneurysms. | 23887838 |
| Inflammation, Neutrophil Infiltration | Altered Intercellular Communication | Pathological examination demonstrated necrotizing inflammation with preponderant neutrophil infiltration, variably atypical mononuclear and multinucleate histiocytes, and numerous mitoses. | 23889356 |
| Vasculitis of large artery, Giant Cell Arteritis, Arteritis, Occlusion of artery (disorder), Intimal proliferation | Altered Intercellular Communication | Giant cell arteritis is a primary large-vessel vasculitis characterized by an arterial wall inflammation associated with intimal hyperplasia leading to arterial occlusion. | 23890680 |
| Inflammation, Polymyositis | Altered Intercellular Communication | Administration of cathepsin B inhibitor CA-074Me reduces inflammation and apoptosis in polymyositis. | 23890703 |
| TNF protein, human, Inflammation, Tumor necrosis, Polymyositis, Infiltration | Altered Intercellular Communication | Consistently, the expression of CB, inflammation score, CD8(+) T-cell, CD68(+) cell, tumor necrosis factor-alpha (TNF-a) infiltration and apoptotic rate were significantly increased in the guinea-pig model of CVB1-induced polymyositis. | 23890703 |
| Inflammation, Polymyositis | Altered Intercellular Communication | Administration of CA-074Me reduced CB expression, decreased inflammation score and attenuated apoptosis in muscle tissues of the guinea-pig model of CVB1-induced polymyositis. | 23890703 |
| Inflammation, Asthma | Altered Intercellular Communication | Fraction of exhaled nitric oxide (Feno) and blood eosinophil count (B-Eos) values, markers of local and systemic eosinophilic inflammation, respectively, are increased in asthmatic patients. | 23890753 |
| Tissue damage, Inflammation | Altered Intercellular Communication | Thus, excessive or chronic inflammation initiated by numerous insults exacerbates tissue damage and - at least in some settings - promotes oncogenesis. | 23891238 |
| Scleritis, Episcleritis | Altered Intercellular Communication | Incidence of scleritis and episcleritis: results from the Pacific Ocular Inflammation Study. | 23891336 |
| Inflammation, Psoriasis, Plaque, Atherosclerotic | Altered Intercellular Communication | Sustained arterial wall inflammation mediated by common cytokines of psoriasis and atherogenesis precedes atherosclerotic plaque development. | 23891393 |
| Inflammation, Erythrocytosis | Altered Intercellular Communication | Constitutive excessive erythrocytosis causes inflammation and increased vascular permeability in aged mouse brain. | 23892106 |
| Gastrointestinal inflammation | Altered Intercellular Communication | Our findings identify RIP2 as a substrate for Pellino3 and Pellino3 as an important mediator in the Nod2 pathway and regulator of intestinal inflammation. | 23892723 |
| Inflammation, Hemorrhage, Edema, Necrosis | Altered Intercellular Communication | Following laparoscopic ileocecectomy, pathology demonstrated haemorrhage, inflammation, oedema and full thickness necrosis of the caecal wall. | 23893271 |
| Inflammation, Asthma | Altered Intercellular Communication | YKL-40 (chitinase-3-like-1) has been introduced as a marker of inflammation in asthma. | 23893808 |
| Inflammation, Bronchospasm, Inflammatory disorder | Altered Intercellular Communication | Asthma is a chronic inflammatory disorder of the airways, which is diagnosed by periodic symptoms of inflammation, bronchial spasm, and increased mucosal secretions. | 23893809 |
| Gingivitis, Dental Plaque, Dental caries | Altered Intercellular Communication | Dental plaque, gingival inflammation, mouth breathing, and dental caries were evaluated by one trained examiner according to World Health Organization [WHO] criteria. | 23893809 |
| allergic inflammation, Respiratory Tract Infections, Infection, Atopy | Altered Intercellular Communication | Allergic inflammation may influence the immunity against infections, so atopic individuals could be susceptible to respiratory infections. | 23894319 |
| Inflammation, Fibrosis Assessment | Altered Intercellular Communication | Chronic inflammation contributes to cardiac fibrosis, a crucial factor in HFpEF; however, inflammatory mechanisms and mediators involved in the development of HFpEF remain unclear. | 23894370 |
| Inflammation, Oral infection, Cardiovascular Diseases | Altered Intercellular Communication | The possible association between oral infection and chronic inflammation and cardiovascular disease risk has been studied intensively. | 23895250 |
| Granuloma, Inflammation, Granuloma Annulare, Necrosis | Altered Intercellular Communication | Excisional biopsy revealed ill-defined granulomas with central necrosis, chronic inflammation and sclerotic collagen; several features consistent with granuloma annulare. | 23895369 |
| Inflammation, Ascites | Altered Intercellular Communication | Laboratory examinations revealed marked inflammation, and abdominal computed tomography showed diffuse thickening of the small intestinal wall and peritoneum, and soft tissue infiltration of the mesentery, without ascites. | 23898495 |
| Inflammation, Cerebral Ischemia | Altered Intercellular Communication | Together, our data suggest that SIRT6 may serve as a potential therapeutic target for HMGB1-mediated inflammation after cerebral ischemia. | 23899523 |
| Inflammation, Primary malignant neoplasm | Altered Intercellular Communication | Telomerase as a potential marker for inflammation and cancer detection in bronchial washing: a prospective study. | 23899579 |
| Inflammation, Primary malignant neoplasm | Altered Intercellular Communication | Random 82 bronchial aspirates were obtained from patients undergoing bronchoscopy to diagnose any lung illness including inflammation and cancer. | 23899579 |
| Inflammation, Primary malignant neoplasm | Altered Intercellular Communication | A significant difference in telomerase activity average was noted between normal patients and those with inflammation and cancer. | 23899579 |
| Inflammation, Primary malignant neoplasm | Altered Intercellular Communication | Discriminatory capacity of telomerase activity was: for cancer vs. non cancer, AUC =0.74 (95% CI: 0.62-0.84), sensitivity=78%, specificity=72%, Negative Predictive Value=87%, at cut-off >0.46 atmol/mg protein/20 min; for cancer vs. normal, AUC=0.87 (95% CI: 0.72-0.96), se=78%, sp=92%, NPV=71%, at cut-off >0.46; for cancer vs. inflammation, AUC=0.69 (95% CI: 0.55-0.80), se=74%, sp=70%, NPV=79%, at cut-off >1.03, and for inflammation vs. normal, AUC=0.76 (95% CI: 0.62-0.88), se=79%, sp=77%, NPV=59%, at cut-off >0. | 23899579 |
| Inflammation, Carcinoma of lung | Altered Intercellular Communication | Telomerase activity in bronchial aspirates is a promising diagnostic marker for lung cancer and inflammation detection. | 23899579 |
| Inflammation | Altered Intercellular Communication | Angiopoietin-2 (Angpt-2), a marker of endothelial cell activation, has been proposed as a mediator of angiogenesis, which might play an important role in the regulation of endothelial integrity and inflammation. | 23899926 |
| Pulmonary arterial hypertension, Inflammation, Polycyclic Hydrocarbons, Aromatic | Altered Intercellular Communication | Pulmonary arterial hypertension (PAH) is a disease of progressive vascular remodeling, characterized by dysregulated growth of pulmonary vascular cells and inflammation. | 23900048 |
| Granulomatous inflammation, Carcinoma, Papillary, Medullary carcinoma | Altered Intercellular Communication | Simultaneous medullary carcinoma, papillary carcinoma and granulomatous inflammation of the thyroid. | 23900477 |
| Granulomatous inflammation, Thyroid carcinoma, Neoplasm Metastasis, C-cell hyperplasia of thyroid | Altered Intercellular Communication | We herein report the case of a 35-year-old man with a mixed medullary-papillary carcinoma of the thyroid, which presented with C-cell hyperplasia, granulomatous inflammation and metastasis to the cervical lymph nodes. | 23900477 |
| Inflammation | Altered Intercellular Communication | In conclusion, the increase of IL-6 in relation to the duration of the intubation indicates an increased risk of inflammation. | 23900683 |
| Inflammation, Neoplasms, Pathology, Vascular lesions, TDP-43 Proteinopathies, Brain Diseases, Metabolic | Altered Intercellular Communication | Further pathologies included a-synucleinopathies (24.9 %), non-Alzheimer tauopathies (23.2 %; including novel forms), TDP-43 proteinopathy (13.3 %), vascular lesions (48.9 %), and others (15.1 %; inflammation, metabolic encephalopathy, and tumours). | 23900711 |
| Inflammation, Nasal Polyps, Nasal congestion (finding) | Altered Intercellular Communication | Oral plus nasal corticosteroids improve smell, nasal congestion, and inflammation in sino-nasal polyposis. | 23901043 |
| Eosinophilic disorder, Nasal inflammation, Nasal congestion (finding) | Altered Intercellular Communication | Combined oral and intranasal corticosteroids improve smell and nasal congestion and decrease nasal inflammation, as measured by reduced tissue eosinophilia and increased detection of nNO. | 23901043 |
| Eosinophilic disorder, Inflammation, Anosmia, Nasal congestion (finding) | Altered Intercellular Communication | Severity of smell loss correlates with degree of nasal congestion but not with inflammation, as measured by tissue eosinophilia or nasally exhaled nNO. | 23901043 |
| Inflammation, Guillain-Barre Syndrome, Familial | Altered Intercellular Communication | Here, we analyze the role of human group IIA secreted phospholipase A2 (sPLA2-IIA), a bactericidal enzyme induced during acute inflammation, in innate immunity against GBS. | 23901095 |
| Inflammatory Bowel Diseases, Inflammation, Dysplasia, Carcinoma | Altered Intercellular Communication | NTSR1 in colonic epithelial cells is overexpressed in IBD, in a stepwise fashion with sequential progress from inflammation to dysplasia and carcinoma. | 23901225 |
| Inflammation, Ulcer | Altered Intercellular Communication | Levels of MMP-9 or TIMP-1 at the ulcer site were associated with the histological severity of activity and inflammation. | 23901237 |
| Hypernatremia, Inflammation, Hypertension, CTCAE, Electrocardiogram: left ventricle hypertrophy (finding) | Altered Intercellular Communication | Hypertension, fluid overload and micro inflammation are associated with left ventricular hypertrophy in maintenance hemodialysis patients. | 23901794 |
| Hypernatremia, Inflammation, Left Ventricular Hypertrophy, HD Term Type, Hypertension, CTCAE | Altered Intercellular Communication | These data support the main conclusions: hypertension, fluid overload and micro inflammation are associated with LVH in maintenance HD patients. | 23901794 |
| Inflammation, Cachexia | Altered Intercellular Communication | Experimental models of cancer cachexia have indicated that systemic inflammation induces muscle-protein breakdown and wasting via muscular nuclear transcription factor kB (NF-kB) activation. | 23902785 |
| Inflammation, Cachexia | Altered Intercellular Communication | Systemic and local inflammation was evident in cachexia and intermediate in precachexia, but the plasma of both patients groups caused ex vivo muscle NF-kB activation. | 23902785 |
| Inflammation, Heart failure, Depression, CTCAE | Altered Intercellular Communication | Researchers have proposed biological (inflammation) and psychological (depression) factors as potential mechanisms for poorer outcomes and readmissions in heart failure (HF) patients. | 23904128 |
| Inflammation, Bipolar Disorder | Altered Intercellular Communication | However, studies investigating the link between inflammation and depressive symptoms in these patients are few. | 23904128 |
| Inflammation, Depression, CTCAE | Altered Intercellular Communication | Our findings add to a growing body of evidence supporting the proposition that heightened inflammation explains the effect depression has on HF. | 23904128 |
| Inflammation, hafnium, Depression, CTCAE | Altered Intercellular Communication | Health care providers should screen for depression in HF patients, as they may be at higher risk of augmented inflammation and poor outcomes. | 23904128 |
| Phagocyte Bactericidal Dysfunction, Musculoskeletal Pain | Altered Intercellular Communication | Phagocyte dysfunction in polymyalgia rheumatica and other age-related, chronic, inflammatory conditions. | 23904438 |
| Inflammation, Arteriovenous fistula | Altered Intercellular Communication | The relationship between arteriovenous fistula success and inflammation. | 23906289 |
| Kidney Failure, Chronic, HD Term Type, Inflammation, Electronic Source Report Form | Altered Intercellular Communication | In this study, the relationship between AVF success and inflammation in patients who had HD due to end-stage renal failure (ESRF) was investigated. | 23906289 |
| HD Term Type, Inflammation | Altered Intercellular Communication | As a result, we think that the evaluation of inflammation before creating AVF in HD patients is very important for increasing the success of AVF. | 23906289 |
| Mesenteric Panniculitis, Hyperplastic Polyp | Altered Intercellular Communication | Mesenteric panniculitis (MP) is an underdiagnosed inflammatory condition of mesenteric adipose tissue. | 23906444 |
| Inflammation, Cardiac Death | Altered Intercellular Communication | Inflammation and sudden cardiac death in a community-based population of older adults: the Cardiovascular Health Study. | 23906927 |
| Inflammation, Cardiac Death, SLC22A5 gene | Altered Intercellular Communication | Inflammation is linked to adverse cardiovascular events, but its association with sudden cardiac death (SCD) has been controversial. | 23906927 |
| Inflammation, SLC22A5 gene | Altered Intercellular Communication | The purpose of this study was to study the association between inflammation and SCD in a community-based population of older adults. | 23906927 |
| Inflammation, Electrocardiogram: myocardial infarction (finding), Heart failure, SLC22A5 gene | Altered Intercellular Communication | Greater burden of inflammation, assessed by IL-6 levels, is associated with SCD risk beyond traditional risk factors, incident myocardial infarction, and heart failure. | 23906927 |
| Communicable Diseases, Inflammation, Connective Tissue Diseases, Aneurysm | Altered Intercellular Communication | A histopathological examination of the aneurysm wall did not detect any significant background factors, such as connective tissue disease, inflammation or infection. | 23906964 |
| Inflammation, neuron death | Altered Intercellular Communication | Treadmill exercise represses neuronal cell death and inflammation during Ab-induced ER stress by regulating unfolded protein response in aged presenilin 2 mutant mice. | 23907580 |
| Neurodegenerative Disorders, Inflammation, Data types - Address, Apoptosis of neurons | Altered Intercellular Communication | ER stress is involved in neurodegenerative diseases including AD, but the molecular mechanisms of neuronal apoptosis and inflammation by Ab-induced ER stress to exercise training are not fully understood. | 23907580 |
| Inflammation, Atherosclerosis | Altered Intercellular Communication | Cyclooxygenase-2 (COX-2) catalyzes the formation of prostaglandins that contribute to the inflammation in atherosclerosis. | 23907768 |
| Inflammation, Neoplasm Metastasis, Tuberculosis | Altered Intercellular Communication | We present a unique case of disseminated tuberculosis presenting initially in the eye solely as a choroidal mass without any inflammation, mimicking choroidal metastasis. | 23907976 |
| Granulomatous inflammation | Altered Intercellular Communication | Fine needle aspiration cytology of the adnexal mass and ascitic fluid revealed granulomatous inflammation with a negative acid-fast bacilli stain. | 23907976 |
| Airway structure, Protease Inhibitors | Altered Intercellular Communication | 25-hydroxyvitamin D (25(OH)D) may be associated with lung function through modulation of pulmonary protease-antiprotease imbalance, airway inflammation, lung remodelling and oxidative stress. | 23908128 |
| Fibrosis Assessment, Metabolic Syndrome X, prostatitis | Altered Intercellular Communication | Metabolic syndrome correlates with peri-urethral fibrosis secondary to chronic prostate inflammation: evidence of a link in a cohort of patients undergoing radical prostatectomy. | 23909794 |
| Fibrosis Assessment, Metabolic Syndrome X, prostatitis | Altered Intercellular Communication | To investigate the pathological relationship between metabolic syndrome and peri-urethral fibrosis status secondary to chronic prostate inflammation. | 23909794 |
| Symptoms, Inflammation, Bladder neck obstruction | Altered Intercellular Communication | A positive correlation was observed between inflammation, International Prostatic Symptoms Score, Bladder Outlet Obstruction Index and collagen amount, whereas inflammation was inversely correlated with elastin amount. | 23909794 |
| Fibrosis Assessment, Metabolic Syndrome X, prostatitis | Altered Intercellular Communication | On multivariate logistic regression analysis, prostate inflammation and metabolic syndrome were the only independent predictors of peri-urethral fibrosis (OR 1.73, 1.52, respectively). | 23909794 |
| Inflammation, Metabolic Syndrome X, prostatitis | Altered Intercellular Communication | The present findings suggest that metabolic syndrome might represent an independent risk factor for prostate inflammation and fibrotic changes secondary to inflammation within the peri-urethral prostatic tissue. | 23909794 |
| palladium, Peyronie Disease | Altered Intercellular Communication | Several studies describing the "natural history" of Peyronie's disease (PD) (Chronic Inflammation of the Tunica Albuginea-CITA) showed that untreated patients with PD seem to have spontaneous improvement. | 23909888 |
| Inflammation, Primary Biliary Cholangitis | Altered Intercellular Communication | Thus, IL-23 and IL-17 may play an important role in the pathogenesis of PBC by promoting inflammation. | 23910013 |
| Diabetes Mellitus, Insulin-Dependent, Choroidal and Ciliary Body Melanoma pT1d TNM Finding v8 | Altered Intercellular Communication | The neurotransmitter Neuropeptide Y (NPY) was previously reported as a minor autoantigen in newly diagnosed type 1 diabetes (T1D) patients. | 23910631 |
| Sinusitis | Altered Intercellular Communication | But nasal and paranasal sinus inflammation is the relative contraindications of TSA. | 23911235 |
| Inflammation, Fibrosis Assessment, Granuloma | Altered Intercellular Communication | The histopathological evaluation comprised myofibroblast foci (MF), intensity of inflammation and fibrosis (Ashcroft score) and numbers of eosinophils and granulomas. | 23911740 |
| Airway structure, ARCN1 gene, Chronic Obstructive Airway Disease | Altered Intercellular Communication | Alveolar macrophages produce neutrophil chemoattractants; this cellular cross-talk contributes to neutrophilic airway inflammation in chronic obstructive pulmonary disease (COPD). | 23912333 |
| Fibrosis Assessment, Hepatotoxicity, Cholestasis, Fatty degeneration | Altered Intercellular Communication | Specific transcriptomic hepatotoxicity signatures were created for CPZ and consisted of inflammation/hepatitis, cholestasis, and liver proliferation in all five donors, as well as fibrosis and steatosis, which were observed in four of five donors. | 23913027 |
| Inflammation, Uveitis, Systemic disease, Herpes Zoster Ophthalmicus | Altered Intercellular Communication | Despite their side-effects and the advent of systemic immunosuppressives and biologics, the use of corticosteroids remains in the management of patients with uveitis, particularly when inflammation is associated with systemic disease or when bilateral ocular disease is present. | 23914773 |
| Inflammation | Altered Intercellular Communication | Perceiving ambivalence toward one's spouse in a support context was linked to greater inflammation even when considering health behaviors, relationship-specific romantic attachment style, spouse negativity/positivity ratings, and overall marital satisfaction. | 23914811 |
| Inflammation, Perforation of pharynx | Altered Intercellular Communication | Even though she had received conservative treatment, exacerbation of inflammation was observed and therefore we performed transoral surgery for closing the pharyngeal perforation. | 23916242 |
| Inflammation, Perforation of pharynx | Altered Intercellular Communication | The pharyngeal perforation smoothly closed and exacerbation of inflammation was not observed, even after oral ingestion began. | 23916242 |
| mucosa-associated lymphoid tissue, Lymphoma, Lymphoproliferative Disorders, Mucosa-Associated Lymphoid Tissue Lymphoma | Altered Intercellular Communication | Of the 1,014 cases of orbital lymphoproliferative disorders 404 (39.8 %) had extranodal mucosa-associated lymphoid tissue (MALT) lymphoma, 156 (15.4 %) had other malignant lymphomas, 191 (18.8 %) had non-IgG4 orbital inflammation, 219 (21.6 %) had IgG4-related orbital inflammation, and 44 (4.3 %) had IgG4-positive MALT lymphoma. | 23917985 |
| Mucosa-Associated Lymphoid Tissue Lymphoma | Altered Intercellular Communication | Median age of the IgG4-related orbital inflammation group was 62 years, which is significantly lower than that of the MALT lymphoma group (median 66 years) and higher than the non-IgG4 orbital inflammation group (median 57 years). | 23917985 |
| Inflammation, Chronic Obstructive Airway Disease, Carcinoma of lung | Altered Intercellular Communication | Local and systemic neutrophilic inflammation in patients with lung cancer and chronic obstructive pulmonary disease. | 23919722 |
| ARCN1 gene, Inflammation, Carcinoma of lung | Altered Intercellular Communication | The results from this study demonstrate higher degree of local and systemic neutrophilic inflammation in patients with lung cancer (with or without COPD) than in patients with COPD. | 23919722 |
| Inflammation, Asthma, Depression, CTCAE | Altered Intercellular Communication | Children with both asthma and depression are at risk for heightened inflammation. | 23919906 |
| Asthma, Depression, CTCAE | Altered Intercellular Communication | To test whether children and adolescents with co-occurring asthma and depression are at risk for elevated inflammation-concurrently and at the next assessment. | 23919906 |
| Inflammation, Asthma, Depression, CTCAE, Chronic disease | Altered Intercellular Communication | The co-occurrence of asthma and depression in childhood poses a risk for substantially elevated inflammation concurrently and over time, which could contribute to pathophysiological processes involved in the development of additional chronic diseases and also to asthma--related morbidity and mortality. | 23919906 |
| vascular inflammations, Atherosclerosis | Altered Intercellular Communication | S100A12 induces vascular inflammation contributing to the development of atherosclerosis. | 23921255 |
| Airway structure, Asthma, Obesity | Altered Intercellular Communication | We found a positive correlation between BMI and FeNO level which suggests a link between obesity and increased airway inflammation in nonasthmatic children. | 23921526 |
| Inflammation, Breast Carcinoma | Altered Intercellular Communication | Local inflammation after tubal ligation may affect ovarian function and breast cancer risk. | 23922107 |
| Inflammation, GDC Disease Response Terminology | Altered Intercellular Communication | Various cytokines associated with inflammation and angiogenesis may contribute to the pathogenesis of DR, and chemokines may be more closely related to the development of this disease. | 23922491 |
| Inflammation | Altered Intercellular Communication | Retinal vascular caliber is associated with cardiovascular biomarkers of oxidative stress and inflammation: the POLA study. | 23923054 |
| Inflammation | Altered Intercellular Communication | This case provides insight into the potential role of chronic inflammation and genetic instability in the pathogenesis of BIA-ALCL. | 23923082 |
| Inflammation, Ichthyosis Bullosa of Siemens | Altered Intercellular Communication | Low-grade inflammation of the intestine may be one of the reasons for development of diarrhoea-predominant IBS (IBS-D). | 23923350 |
| Inflammation | Altered Intercellular Communication | Our results indicate that mild inflammation is involved in IBS-D patients as proinflammatory cytokines were increased although no difference in anti-inflammatory cytokine was observed. | 23923350 |
| Tubulitis Assessment, Inflammation, Interstitial inflammation | Altered Intercellular Communication | On the protocol biopsies, interstitial inflammation (Banff i scores) and tubulitis (Banff t scores) were more likely in the r-ATG group at one month, but at four and 12 months, both inflammation and tubulitis were more likely in the alemtuzumab group. | 23924146 |
| Pain Distress Question, Endophthalmitis, CTCAE, Inflammation | Altered Intercellular Communication | However, normal post-operative pain and inflammation may mask endophthalmitis and lead to delayed diagnosis and grave visual consequences. | 23924462 |
| Inflammation, Chronic disease | Altered Intercellular Communication | Intense marrow iron examination provides a useful iron status classification which is of particular importance in cases of chronic diseases and inflammation. | 23924552 |
| Inflammation, Inflammatory Myofibroblastic Tumor | Altered Intercellular Communication | The presence of ALK-1 positivity within the spindle cells, coupled with the prominent inflammation indicated a diagnosis of ALK-1 positive inflammatory myofibroblastic tumour (IMT-the neoplastic member of the so called inflammatory pseudotumours). | 23927068 |
| Inflammation, Ischemia | Altered Intercellular Communication | Oxidation of unsaturated lipids generates reactive aldehydes that accumulate in tissues during inflammation, ischemia, or aging. | 23928303 |
| Inflammation, Obesity | Altered Intercellular Communication | Severe obesity is associated with a state of chronic inflammation. | 23928404 |
| Inflammation, Weight decreased | Altered Intercellular Communication | Extensive weight loss increases sirtuin expression significantly both in adipose tissue and liver, probably as a consequence of reduced inflammation. | 23928404 |
| Inflammation, Anemia, Chronic Kidney Diseases, Diabetes Mellitus | Altered Intercellular Communication | Multivariate regression model revealed RDW as a significant predictor of FMD independent of major confounding factors, such as diabetes, inflammation, anemia and kidney function in CKD. | 23928544 |
| Inflammation, Calcinosis | Altered Intercellular Communication | Aortic valve (AV) calcification occurs via a pathophysiological process that includes lipoprotein deposition, inflammation, and osteoblastic differentiation of valvular interstitial cells. | 23928865 |
| Inflammation, Malnutrition, Chronic Kidney Diseases, Cardiovascular Diseases | Altered Intercellular Communication | Malnutrition and/or inflammation may modify the risk relationship of total cholesterol with cardiovascular disease in CKD patients. | 23929929 |
| Inflammation | Altered Intercellular Communication | With Masson staining, there was increased connective tissue and no inflammation. | 23930362 |
| Communicable Diseases, Inflammation | Altered Intercellular Communication | A low prime volume is expected to improve blood conservation and decrease donor exposure, prevent drawbacks of transfusion (immunomodulation, infection), increase the incidence of blood-free surgery in smaller babies, and decrease whole body systemic inflammation by decreasing surface of foreign material in contact with blood and inflammation associated with blood transfusion. | 23930382 |
| Inflammation | Altered Intercellular Communication | Chronic traffic pollution exposure is associated with eosinophilic, but not neutrophilic inflammation in older adult asthmatics. | 23931679 |
| Inflammation, Asthma | Altered Intercellular Communication | Poorly controlled asthma in older adults is associated with eosinophilic and neutrophilic inflammation. | 23931679 |
| Inflammation | Altered Intercellular Communication | Chronic residential traffic pollution exposure may be associated with eosinophilic, but not neutrophilic inflammation in older asthmatics. | 23931679 |
| Inflammation, Neoplasms | Altered Intercellular Communication | He underwent urgent resection and histological examination revealed tumor cells in a mucopolysaccharide matrix and bacterial colonies along with active inflammation. | 23931763 |
| Inflammation, Disorder of tendon | Altered Intercellular Communication | Peritendinous injection of corticosteroid is the commonly accepted strategy despite the absence of inflammation in tendinopathy. | 23931981 |
| Refractory anemias, Inflammation | Altered Intercellular Communication | TCZ8 strongly inhibited the biomarkers of joint tissue remodeling suggesting that TCZ actively suppresses key pathobiological processes at the site of inflammation in RA patients. | 23932312 |
| Inflammation | Altered Intercellular Communication | We examined thrombospondin-1 (THBS1, alias TSP-1) expression in human synovial tissue (ST) during the resolution phase of chronic inflammation and elucidated its transcriptional regulation by the orphan receptor 4A2 (NR4A2). | 23933487 |
| Inflammation, Fibrosis Assessment, Fatty degeneration | Altered Intercellular Communication | Although histological steatosis, inflammation, and fibrosis did not change after treatment, liver fibrosis improved in seven patients (41.2%), progressed in five (29.4%), and remained unchanged in five (29.4%). | 23933938 |
| Inflammation, Fibrosis Assessment, Fatty degeneration | Altered Intercellular Communication | Linear regression analysis confirmed an independent association of liver fibrosis, steatosis, inflammation, and hepatocyte ballooning with hepatic chemerin mRNA expression (P<0.05 respectively). | 23935128 |
| Hepatitis, Fatty Liver Disease | Altered Intercellular Communication | This is the first study to show that chemerin mRNA expression is significantly elevated in the liver of NASH patients and that CMKLR1 expression is upregulated in liver inflammation, whereby IL6 could play a causal role. | 23935128 |
| Sepsis, Inflammation, Multiple Organ Failure, physiopathological | Altered Intercellular Communication | In systemic inflammation and sepsis, endothelial activation and microvascular dysfunction are characteristic features that promote multiorgan failure. | 23935249 |
| Single organ dysfunction, Inflammation | Altered Intercellular Communication | SDMA levels closely correlated with disease severity scores, biomarkers of inflammation, and organ failure (renal, hepatic, and circulatory). | 23935249 |
| Non-alcoholic Fatty Liver Disease, Inflammation, Liver damage | Altered Intercellular Communication | Meanwhile, among subjects with NAFLD, index of liver damage, such as elevated ALT combined with genetic susceptibility to inflammation associated with increased SUA levels. | 23935829 |
| Inflammation, Ischemia | Altered Intercellular Communication | Inflammation occurring in the central nervous system (CNS) in association with ischemia is caused by immune cells including monocytes and involved in lesion expansion. | 23936327 |
| Inflammation, Plaque, Atherosclerotic | Altered Intercellular Communication | We showed that atherosclerotic plaque areas in the AngII-infused Apo E KO mice and markers of inflammation such as RAGE, ICAM-1, VCAM-1, and MCP-1 were increased in aorta compared to that of the Apo E KO mice. | 23936343 |
| Long-Term Synaptic Depression, Depression, CTCAE | Altered Intercellular Communication | These mice also show significant abnormalities in basal synaptic transmission, paired-pulse facilitation and long-term depression (LTD). | 23936403 |
| AICARDI-GOUTIERES SYNDROME, Gastritis | Altered Intercellular Communication | To identify the contributions of g-glutamyltranspeptidase and asparaginase to gastric cell inflammation, human gastric epithelial cells (AGS line) were infected with H. pylori wild-type and knockout strains and inflammatory responses evaluated by induction of interleukin-8 (IL-8). | 23937242 |
| Inflammation, Infection caused by Helicobacter pylori | Altered Intercellular Communication | These data suggest that g-glutamyltranspeptidase plays a significant role in the chronic inflammation caused by H. pylori infection. | 23937242 |
| Inflammation | Altered Intercellular Communication | Epicardial adipose tissue (EAT), deposited around subepicardial coronary vessels, may contribute directly to perivascular inflammation and smooth muscle cell proliferation. | 23937273 |
| Immunocompromised Host | Altered Intercellular Communication | We report an exaggerated dermatological inflammatory condition in an immunocompromised patient. | 23937292 |
| Inflammation, Appendicitis, CTCAE | Altered Intercellular Communication | When CT shows focal inflammation anywhere within the abdomen, along with an abnormal SMA/SMV relationship, the position of the caecum should be ascertained and acute appendicitis ruled out. | 23937823 |
| Inflammation, Malignant Neoplasms, Necrosis | Altered Intercellular Communication | Necrosis is a common feature of various malignant tumors, which also has two opposing effects: pro-tumor by chronic inflammation and anti-tumor by effective cell clearance. | 23938031 |
| Primary malignant neoplasm | Altered Intercellular Communication | Prognostic factors in patients with advanced cancer: a comparison of clinicopathological factors and the development of an inflammation-based prognostic system. | 23938289 |
| Inflammation, Primary malignant neoplasm | Altered Intercellular Communication | Biomarkers of systemic inflammation may have prognostic value in advanced cancer. | 23938289 |
| Primary malignant neoplasm | Altered Intercellular Communication | A systemic inflammation-based score, mGPS, and performance status predict survival in advanced cancer. | 23938289 |
| Inflammation, Tissue injury | Altered Intercellular Communication | The principal findings revealed almost exclusive inflammation and tissue injury in the hypothalamus. | 23939463 |
| Inflammation | Altered Intercellular Communication | Inflammation was associated with complete loss of hypocretinergic neurons. | 23939463 |
| Candida albicans, Inflammation, Candida (fungus) | Altered Intercellular Communication | Oral mucosa inflammation other than irradiation is mostly caused by Candida albicans, yeast of Candida genus. | 23940987 |
| Inflammation, Hepatitis B, Hepatocarcinogenesis | Altered Intercellular Communication | Persistent inflammation together with genetic/epigenetic aberrations is strongly associated with chronic Hepatitis B virus (HBV) infection-related hepatocarcinogenesis. | 23941364 |
| Degenerative polyarthritis, Inflammation | Altered Intercellular Communication | Synovial fluid levels of bradykinin correlate with biochemical markers for cartilage degradation and inflammation in knee osteoarthritis. | 23942063 |
| Degenerative polyarthritis, Inflammation, Osteoarthritis, Knee | Altered Intercellular Communication | To determine the content of bradykinin (BK) and markers of cartilage degradation and inflammation in the synovial fluid (SF) of patients with knee osteoarthritis (OA), and to evaluate correlations with biomarkers or clinical parameters. | 23942063 |
| Degenerative polyarthritis, Inflammation | Altered Intercellular Communication | The presence of BK in the knee OA SF and its correlations with cartilage degradation and inflammation markers of OA support its participation in OA pathology. | 23942063 |
| Ischemic stroke | Altered Intercellular Communication | An association between poor oral health and an increased risk of ischaemic stroke has been recognised through the oral infection-inflammation pathway. | 23942139 |
| Inflammation, Lower gastrointestinal hemorrhage, Endothelial dysfunction, Depression, CTCAE | Altered Intercellular Communication | Endothelial dysfunction (ED), low-grade inflammation (LGI) and oxidative stress (OxS) may be involved in the pathobiology of depression. | 23942242 |
| Inflammation, Obesity | Altered Intercellular Communication | Macrophage infiltration into adipose tissue during obesity and their phenotypic conversion from anti-inflammatory M2 to proinflammatory M1 subtype significantly contributes to develop a link between inflammation and insulin resistance; signaling molecule(s) for these events, however, remains poorly understood. | 23943623 |
| Alzheimers Disease", Inflammation Mediators, Nerve Degeneration | Altered Intercellular Communication | The results suggest that, in the long term, amyloid-b immunotherapy results in downregulation of microglial activation and potentially reduces the inflammation-mediated component of the neurodegeneration of Alzheimer's disease. | 23943781 |
| Inflammation | Altered Intercellular Communication | The mechanisms underlying the involvement of the complement system are not understood, although complement and inflammation have been implicated in drusen formation. | 23943789 |
| Inflammation | Altered Intercellular Communication | The NLRP-3 (nucleotide-binding domain, leucine-rich-containing family, pyrin domain-containing-3) inflammasome has recently emerged as a pivotal regulator of chronic inflammation. | 23944632 |
| Inflammation | Altered Intercellular Communication | Because anti-Neu5Gc Abs can promote chronic inflammation, the long-term safety of living and acellular pig tissue implants in recipients warrants further evaluation. | 23945141 |
| Sample Size Calculation | Altered Intercellular Communication | Biomarkers of inflammation/endothelial activation were generally increased among SSc patients. | 23945149 |
| Inflammation, Neoplasms | Altered Intercellular Communication | Chronic inflammation has been recognized to foster tumour development. | 23945200 |
| Inflammation, Abscess of testis | Altered Intercellular Communication | [A case of testicular abscess with low-grade inflammation]. | 23945330 |
| Inflammation, Abscess of testis | Altered Intercellular Communication | We report a case of testicular abscess with low-grade inflammation. | 23945330 |
| Inflammation | Altered Intercellular Communication | The clinical course of this case was unusual because of the small extent of inflammation observed. | 23945330 |
| Inflammation, Abscess of testis | Altered Intercellular Communication | Typically, testicular abscess is characterized by severe systemic and local inflammation. | 23945330 |
| Inflammation, Inflammatory abnormality of the eye | Altered Intercellular Communication | To evaluate the high-speed anterior segment optical coherence tomography (AS-OCT) grading of the AS inflammation in patients with ocular inflammation. | 23945636 |
| Granulomatous inflammation | Altered Intercellular Communication | Histopathological study of the resected adenoid revealed caseating granulomatous inflammation. | 23946986 |
| Communicable Diseases, Inflammation, Optic Neuritis | Altered Intercellular Communication | Optic neuritis is an acute inflammation of the optic nerve and, in its atypical form, is caused by inflammation of the optic nerve as part of infectious, immune, granulomatous, or contiguity processes. | 23947007 |
| Communicable Diseases, Inflammation | Altered Intercellular Communication | We hypothesized that DNA condensation by cationic polypeptides in CF sputum would result in a better control of CF inflammation and infection. | 23947381 |
| Pseudomonas aeruginosa, Inflammation | Altered Intercellular Communication | It retains antimicrobial properties against Pseudomonas aeruginosa and Staphylococcus aureus at doses that induce no inflammation in the mouse lung after aerosol administration. | 23947381 |
| Inflammation, Primary malignant neoplasm | Altered Intercellular Communication | Clinical experience with intravenous administration of ascorbic acid: achievable levels in blood for different states of inflammation and disease in cancer patients. | 23947403 |
| Inflammation, Neoplasms | Altered Intercellular Communication | The data indicate that, while potentially therapeutic plasma ascorbate concentrations can be achieved with IVC, levels attained will vary based on tumor burden and degree of inflammation (among other factors). | 23947403 |
| Inflammation, Primary malignant neoplasm | Altered Intercellular Communication | Evidence suggests that IVC may be able to modulate inflammation, which in turn might improve outcomes for cancer patients. | 23947403 |
| Inflammation, Bursitis | Altered Intercellular Communication | Iliopsoas bursitis (IB) is characterized by inflammation and enlargement of the iliopsoas bursa. | 23948843 |
| Alzheimers Disease", Data types - Address | Altered Intercellular Communication | Synaptic alterations are reported to be seen in Alzheimer's disease (AD) and the suggested function of SLC10A4 as a vesicular transporter for cholinergic neurotransmitters proposes a link between this protein and AD. | 23948907 |
| Inflammation, Necrosis | Altered Intercellular Communication | Mild chronic inflammation, hemosiderin, and coagulative necrosis were also observed. | 23948957 |
| Refractory anemias, Rheumatoid Arthritis, Autoimmune Diseases, Inflammation | Altered Intercellular Communication | Rheumatoid arthritis (RA) is one of the most common autoimmune diseases that result in chronic inflammation of the joints. | 23949659 |
| vascular inflammations | Altered Intercellular Communication | This may identify IL-19 as a novel therapeutic to limit vascular inflammation. | 23950143 |
| Pain Distress Question, Myelitis, neuromyelitis | Altered Intercellular Communication | Although spinal cord inflammation is a defining aspect of neuromyelitis, there is an almost complete lack of data on altered somatosensory function, including pain. | 23951176 |
| Inflammation, Endothelial dysfunction, Cardiovascular Diseases | Altered Intercellular Communication | Elevated plasma levels of asymmetric dimethylarginine (ADMA) have been reported to be associated with endothelial dysfunction, inflammation, and oxidative stress in multiple cardiovascular diseases. | 23951217 |
| Inflammation, Arthropathy | Altered Intercellular Communication | This exploratory investigation featuring a variety of joint disorders revealed that measuring the relative proportions of inflammatory cell types may aid in synovial tissue classification if the samples are also stratified according to the intensity of inflammation. | 23951325 |
| Inflammation, Chagas Disease, Liver damage | Altered Intercellular Communication | We investigated the pathological and diagnostic role of selected markers of inflammation, oxidant/antioxidant status, and cellular injury in human Chagas disease. | 23951383 |
| Gastroesophageal reflux disease, Inflammation | Altered Intercellular Communication | High levels of fractions of sialic acids were set, that was associated with the protein fructose, fractions of hydroxyproline in children with GERD compared with the patients with DG, which testify to the process of degradation of collagen and may be one of the factors contributing to the local inflammation of the esophagus and gastroduodenal zone of the digestive tract. | 23951893 |
| Inflammation, Dyslipidemias | Altered Intercellular Communication | The features of proatherogenic disorders connected with dominating types of dyslipidemias, the degree of chronic inflammation manifestation and some results of hormonal background were established for people with certain reproductive status. | 23951911 |
| Inflammation, Dyslipidemias | Altered Intercellular Communication | The features of proatherogenic disorders connected with dominating types of dyslipidemias, the degree of chronic inflammation manifestation and some results of hormonal background were established for people with certain reproductive status. | 23951911 |
| Inflammation | Altered Intercellular Communication | Pentraxin-3 (PTX3) is a multifactorial protein involved in immunity and inflammation, which is rapidly produced and released by several cell types in response to inflammatory signals. | 23952075 |
| Inflammation | Altered Intercellular Communication | It may be suggested that PTX3 is related with periodontal tissue inflammation. | 23952075 |
| Inflammation | Altered Intercellular Communication | Pentraxin-3 (PTX3) is a multifactorial protein involved in immunity and inflammation, which is rapidly produced and released by several cell types in response to inflammatory signals. | 23952075 |
| Hypertensive disease, Inflammation, Diabetes Mellitus, Non-Insulin-Dependent | Altered Intercellular Communication | [Effect of perindopril on the processes of subclinical inflammation in patients with arterial hypertension and type 2 diabetes mellitus]. | 23952947 |
| ARCN1 gene, Inflammation, Carcinoma of lung | Altered Intercellular Communication | Oxidative stress and inflammation in the normal airways and blood of patients with lung cancer and COPD. | 23954470 |
| ARCN1 gene, Inflammation | Altered Intercellular Communication | Regardless of the presence of an underlying respiratory condition (COPD), protein oxidation, oxidatively damaged DNA, and inflammation were remarkably increased in the normal airways and blood of patients with LC. | 23954470 |
| Inflammation, Rheumatic Heart Disease | Altered Intercellular Communication | Aberrantly high levels of CD306 were found in the sera of pregnant women and patients with inflammation and rheumatic heart disease and in the urine of pregnant women. | 23954474 |
| Inflammation, Vascular calcification | Altered Intercellular Communication | Vascular calcifications and bone health seem to be etiologically linked via common risk factors such as aging and subclinical chronic inflammation. | 23954758 |
| Inflammation, Hypertensive (finding) | Altered Intercellular Communication | Cystatin C was associated with the severity of regurgitation independent of renal function body composition chronic inflammation LV remodeling and diastolic function in hypertensive patients with mild-to-moderate AR. | 23954770 |
| Barrett Esophagus, Inflammation, Adenocarcinoma Of Esophagus | Altered Intercellular Communication | Barrett's esophagus (BE) is known to progress to esophageal adenocarcinoma in a setting of chronic inflammation. | 23955118 |
| Carcinogenesis | Altered Intercellular Communication | Toll-like receptor (TLR) 4 has been linked to inflammation-associated carcinogenesis. | 23955118 |
| Inflammation, Anastomosis - action | Altered Intercellular Communication | These findings suggest that barium was embedded in the submucosa and lamina propria with manipulation of the stapled anastomosis and that the barium trapped in the anastomotic site caused persistent inflammation, resulting in an anastomotic stricture. | 23955478 |
| Tissue damage, Inflammation | Altered Intercellular Communication | High-sensitivity C-reactive protein (hs-CRP) is an extremely sensitive systemic marker of inflammation and tissue damage, and increased levels of hs-CRP are strongly associated with inflammatory reactions. | 23955613 |
| palladium, Inflammation, Presenile dementia | Altered Intercellular Communication | It is known that inflammation plays a role in the pathogenesis of PD and dementia. | 23955613 |
| Inflammation, Asthma, Respiratory Hypersensitivity, Congenital Abnormality | Altered Intercellular Communication | Subjects with asthma with (3)He ventilation defects were older with significantly worse airway hyper-responsiveness, inflammation and airway remodelling but similar FEV1 as subjects with asthma without defects; hyperpolarised (3)He ventilation abnormalities were spatially and quantitatively related to abnormally remodelled airways. | 23956019 |
| Saint Lucia, GDC Molecular Consequence Terminology, Acute and chronic inflammation, Colitis | Altered Intercellular Communication | Dysregulated T cell responses in the intestine may lead to chronic bowel inflammation such as collagenous colitis (CC) and lymphocytic colitis (LC), together known as microscopic colitis (MC). | 23956982 |
| Inflammation | Altered Intercellular Communication | AGEs have been shown to contribute to chronic inflammation and oxidative stress in humans. | 23957669 |
| Autoimmune Diseases, Inflammation | Altered Intercellular Communication | Interactions between DCs and regulatory T cells (Treg), which regulate immune response by attenuating acute inflammation, are postulated to be involved in the pathogenesis of autoimmune diseases. | 23958259 |
| Inflammation | Altered Intercellular Communication | The results of our study provide novel insights in the direct interaction of mature DCs and Treg in plaque inflammation and stability. | 23958259 |
| HD Term Type, Inflammation | Altered Intercellular Communication | We hypothesized that the association of low IGF-1 with chronic inflammation may increase the mortality risk in HD patients. | 23958273 |
| Inflammation | Altered Intercellular Communication | It is suggested that local activation of these sensory nerves may involve dural mast cells as one factor in local inflammation, causing sensitization of meningeal nociceptors. | 23958278 |
| Toxic nephropathy, Nephritis | Altered Intercellular Communication | Moreover, renal inflammation is observed in CNI nephrotoxicity but the mechanisms are poorly understood. | 23958496 |
| Degenerative polyarthritis, Inflammation, Degenerative disorder of cartilage | Altered Intercellular Communication | Osteoarthritis (OA) is a complex disease characterized by cartilage degeneration, secondary synovial membrane inflammation and subchondral bone changes. | 23958877 |
| Inflammation, Hepatitis C, Liver Cirrhosis, Diabetes Mellitus | Altered Intercellular Communication | In hepatitis C, continuous inflammation mediated by TNF-a leads to liver cirrhosis and diabetes mellitus. | 23961783 |
| Inflammation, Hypertension, CTCAE, Diabetes Mellitus | Altered Intercellular Communication | HCV+ psoriatic patients were less obese, but still had a higher frequency of diabetes mellitus and hypertension, possibly due to chronic inflammation in the liver and other organs. | 23961783 |
| Inflammation | Altered Intercellular Communication | Elevated MMP-to-TIMP ratios and MMP activity suggest an imbalance in tear MMP regulation that may explain the predisposition of these patients to demonstrate corneal melting and chronic complications associated with persistent inflammation. | 23962653 |
| Tears body substance, Inflammatory abnormality of the eye | Altered Intercellular Communication | Myeloperoxidase in tears may be a sensitive and specific marker for the quantification of ocular inflammation. | 23962653 |
| Liver Failure, Inflammation, Malnutrition, Failure (biologic function) | Altered Intercellular Communication | Chronic inflammation, malnutrition, and liver failure causing an impaired healing capacity are important reasons for failure. | 23963028 |
| Inflammation, Neck Pain | Altered Intercellular Communication | Non-steroidal anti-inflammatory drugs (NSAIDs) may be used to reduce neck pain and associated inflammation and facilitate earlier recovery. | 23964752 |
| Inflammation, hepcidin | Altered Intercellular Communication | Also relations between visfatin and hepcidin, demands for recombinant human erythropoietin (rHuEpo), inflammation, and situations characterized by insulin resistance were evaluated. | 23964827 |
| Inflammation, Anemia, Hyperferritinaemia | Altered Intercellular Communication | Seven patients appeared to have anemia of chronic inflammation, and in 5 patients, there was no clearly definable cause for hyperferritinemia. | 23965472 |
| Inflammation | Altered Intercellular Communication | In addition, extremely high ferritin levels can be found in patients with seemingly indolent disease or levels of chronic inflammation. | 23965472 |
| Adult-Onset Still Disease, Lymphohistiocytosis, Hemophagocytic, Systemic onset juvenile chronic arthritis | Altered Intercellular Communication | A markedly elevated serum ferritin level has been associated with inflammatory conditions such as adult-onset Still's disease, systemic juvenile idiopathic arthritis, and hemophagocytic lymphohistiocytosis/macrophage activation syndrome. | 23965472 |
| Inflammation, Subacute Bacterial Endocarditis, Fever, CTCAE | Altered Intercellular Communication | The diagnosis of infectious endocarditis caused by the HACEK group containing C. hominis may become difficult because the fever was not so high and inflammation was not so severe. | 23965861 |
| Inflammation, Carcinogenesis | Altered Intercellular Communication | Chronic inflammation may play a role in ovarian carcinogenesis. | 23966559 |
| ovarian neoplasm, Inflammation | Altered Intercellular Communication | Our results support the hypothesis that higher levels of circulating CRP are associated with increased risk of ovarian cancer, indicating that the role of inflammation in ovarian cancer requires further elucidation. | 23966559 |
| Primary malignant neoplasm, Ulcerative Colitis, Colitis | Altered Intercellular Communication | The aim of this work was to access the expression profile of proteins involved in colonic inflammation and cancer in samples from CD and UC. | 23967107 |
| Inflammation, Medically Unexplained Symptoms, Depression, CTCAE, Choline Dehydrogenase, Mitochondrial | Altered Intercellular Communication | Only the somatic symptom dimension of depression was associated with CHD, biomarkers (inflammation, vascular function) and cardio-vascular risk factors. | 23967272 |
| Somatic, Inflammation, Depression, CTCAE, Choline Dehydrogenase, Mitochondrial | Altered Intercellular Communication | Thus, our results partly confirm current models: Somatic, but not cognitive-affective symptom dimensions are responsible for the association between depression and CHD, inflammation, vascular function and cardiovascular risk factors in the general population. | 23967272 |
| Inflammation, Coronary Arteriosclerosis, Depression, CTCAE, physiopathological | Altered Intercellular Communication | However, our findings challenge the assumptions that somatic depression might be due to inflammation or vascular dysfunction as consequence of progressed atherosclerotic disease. | 23967272 |
| Inflammation, Intimal proliferation | Altered Intercellular Communication | However, the application and use of stent struts induces local and systemic inflammation, leading to intractable neointimal hyperplasia. | 23968847 |
| Inflammation, Arteriopathic disease | Altered Intercellular Communication | CD4(+) T cells are involved in artery stenosis diseases, but little is known about the influence of the CD4(+) T cells on the inflammation reaction after stent implantation. | 23968847 |
| Inflammation | Altered Intercellular Communication | We speculate that the maintenance of the frequency and function of Tregs controls the inflammatory response, which otherwise induces acute inflammation after stent implantation. | 23968847 |
| Chronic lymphocytic inflammation, Clippers | Altered Intercellular Communication | For the first time we describe and interpret Susceptibility Weighted Imaging (SWI) and Perfusion Weighted Imaging (PWI) findings in a case of Chronic Lymphocytic Inflammation with Perivascular Pontine Enhancement Responsive to Steroids (CLIPPERS). | 23969198 |
| Inflammation, Cardiovascular Diseases | Altered Intercellular Communication | The study investigates whether productive activities by older adults reduce bodily inflammation, as indicated by C-reactive protein (CRP), a biomeasure associated with the risk of cardiovascular diseases. | 23969258 |
| Inflammation, Hypertension, CTCAE, Cardiovascular Diseases | Altered Intercellular Communication | Productive activities-and frequent volunteering in particular-may protect individuals from inflammation that is associated with increased risk of hypertension and cardiovascular disease. | 23969258 |
| Inflammation | Altered Intercellular Communication | The mean methylation level of the FHIT gene was associated with intratumoral inflammation. | 23969757 |
| physiopathological | Altered Intercellular Communication | We discuss the multifactorial origin, involving peripheral nerve dysfunction and hormonal dysfunction, as well as psychological traits. | 23970045 |
| Drug Eruptions, Communicable Diseases, Inflammation, Neoplasms | Altered Intercellular Communication | The patients were categorized into patients with infection, inflammation, neoplasm and drug-induced fever. | 23970321 |
| Inflammation, Neoplasms | Altered Intercellular Communication | The effectiveness of PET-CT and tissue biopsy for diagnosis was considerably high, particularly in the categories of neoplasm and nonspecific inflammation, respectively, though the effectiveness of bacterial culture was low. | 23970321 |
| Inflammation | Altered Intercellular Communication | Pyothorax-associated lymphoma (PAL) is a representative form of diffuse large B-cell lymphoma associated with chronic inflammation, in which the Epstein-Barr virus (EBV) genome is consistently detectable in the lymphoma cells of all PAL cases. | 23972300 |
| Inflammation, GRN wt Allele | Altered Intercellular Communication | In the in vitro inflammation models, PGRN suppressed both the neutrophil chemotaxis and ICAM-1 expression caused by TNF-a in endothelial cells. | 23972823 |
| Inflammation, GRN wt Allele | Altered Intercellular Communication | PGRN exerted ameliorative effects against I/R-induced inflammation, and these effects may be due to the inhibition of neutrophil recruitment into the I/R brain. | 23972823 |
| Inflammation | Altered Intercellular Communication | However, it is not clear if lower background exposure to PAHs is associated with inflammation in humans, independent of smoking, a major source of PAHs. | 23972896 |
| Degenerative polyarthritis, Pain Distress Question, Inflammation | Altered Intercellular Communication | Knee osteoarthritis (OA) pain is suggested to be associated with inflammation and detrimental mechanical loading across the joint. | 23973128 |
| Inflammation, Pain Distress Question | Altered Intercellular Communication | In this cross-sectional study, we simultaneously examined the inflammation and alignment of the lower limb and examined how the pain components varied depending on the disease progression. | 23973128 |
| Inflammation, Synovitis | Altered Intercellular Communication | The serum interleukin (sIL)-6 level reflecting synovitis, and the high sensitivity C-reactive protein (hs-CRP) level were measured to evaluate the severity of inflammation. | 23973128 |
| Degenerative polyarthritis, Inflammation | Altered Intercellular Communication | Synovial material from patients with knee OA exhibited different degrees of inflammation. | 23973153 |
| Inflammation | Altered Intercellular Communication | Synovial material without inflammation exhibited a similar vascular and neuronal network as the normal knee joint from rat and sheep. | 23973153 |
| Inflammation, Fibrosis Assessment, Fatty degeneration | Altered Intercellular Communication | Plasma CK-18 raised significantly with any increase in steatosis, inflammation and fibrosis, but there was a significant overlap across disease severity. | 23973932 |
| Inflammation, Fibrosis Assessment, Fatty degeneration, Metabolic Syndrome X | Altered Intercellular Communication | CK-18 correlated most strongly with ALT (r=0.57, p<0.0001) and adipose tissue IR (insulin-suppression of FFA: r=-0.43; p<0.001), less with steatosis, lobular inflammation and fibrosis (r=0.28-0.34, all p<0.001), but not with ballooning, BMI, metabolic syndrome or T2DM. | 23973932 |
| Inflammation, Lymphohistiocytosis, Hemophagocytic | Altered Intercellular Communication | Hemophagocytic lymphohistiocytosis (HLH) is an aggressive and potentially life-threatening condition characterized by uncontrolled hyper inflammation caused by various inherited or acquired immune deficiencies. | 23974460 |
| Inflammatory, Inflammation, Uterine Cervicitis | Altered Intercellular Communication | Among the inflammatory lesions, chronic non-specific cervicitis was the most commonly encountered lesion constituting 72.2% of all inflammation. | 23974733 |
| Conjunctivitis | Altered Intercellular Communication | After a few recurrences of mild corneal and conjunctival inflammation, a second conjunctival biopsy was performed at a different site in the same eye, 30 months later. | 23974895 |
| Fibrosis Assessment, Conjunctivitis | Altered Intercellular Communication | Despite its rarity in the pediatric age group, MMP should be considered in the differential diagnosis of chronic conjunctival inflammation and fibrosis. | 23974895 |
| Inflammation, Macular edema due to diabetes mellitus, Dystonia, Dopa-Responsive, due to Sepiapterin Reductase Deficiency | Altered Intercellular Communication | The significant association of SRD with intravitreal IL-6 indicates that inflammation may play an important role in the development of SRD in diabetic macular edema. | 23975003 |
| Inflammation, Dental Plaque, Calcinosis, Vascular calcification | Altered Intercellular Communication | Vascular calcification correlates with inflammation and plaque instability in a dual manner, depending on the spotty/granular (micro) or sheet-like/lamellated (macro) pattern of calcification. | 23975852 |
| Inflammation, Calcinosis | Altered Intercellular Communication | Modified lipoproteins trigger both inflammation and calcification via receptors for advanced lipoxidation/glycation endproducts (ALEs/AGEs). | 23975852 |
| Osteogenesis, Inflammation | Altered Intercellular Communication | These data indicate a novel molecular mechanism by which galectin-3 and RAGE modulate in divergent ways, not only inflammation, but also vascular osteogenesis, by modulating Wnt/b-catenin signalling, and independently of ALEs/AGEs. | 23975852 |
| Inflammation, Non-alcoholic Fatty Liver Disease | Altered Intercellular Communication | Adiponectin has a central role in regulating glucose and lipid metabolism and controlling inflammation in insulin-sensitive tissues and low adiponectin levels have been linked to NAFLD. | 23977033 |
| Inflammation, Demyelination, Axonal loss, Demyelinating Diseases | Altered Intercellular Communication | Multiple sclerosis is the most frequent demyelinating disease in the human CNS characterized by inflammation, demyelination, relative axonal loss and gliosis. | 23977356 |
| Inflammation, Impaired cognition, glycation | Altered Intercellular Communication | We examined the clinical value of two serum markers of low-grade inflammation, C-reactive protein (CRP) and receptor of advanced glycation products (RAGE), as prognostic indices for cognitive decline. | 23978069 |
| Inflammation, Impaired cognition | Altered Intercellular Communication | Chronic low-grade inflammation is present in patients with cognitive impairment. | 23978069 |
| Inflammation, Failure (biologic function) | Altered Intercellular Communication | Better patient outcomes are achieved by treating CD at early inflammation stages; delayed treatment increases rates of treatment failure. | 23978351 |
| Inflammation, Hepatitis C | Altered Intercellular Communication | HIV and HCV infections contribute to chronic inflammation; however, reduced CRP possibly occurs through HCV-mediated mechanisms. | 23978997 |
| Vasculitis, Dental Plaque | Altered Intercellular Communication | Impact of cardiovascular risk factors on vessel wall inflammation and calcified plaque burden differs across vascular beds: a PET-CT study. | 23979062 |
| Vasculitis, Dental Plaque | Altered Intercellular Communication | Findings of this PET/CT study demonstrate that the impact of cardiovascular risk factors on vessel wall inflammation and calcified plaque burden differs across vascular territories. | 23979062 |
| Inflammation, Atrial Fibrillation by ECG Finding | Altered Intercellular Communication | Increasing evidence indicates that inflammation contributes to the pathogenesis of atrial fibrillation (AF). | 23979265 |
| Inflammation, Atrial Fibrillation | Altered Intercellular Communication | In this study, we investigated whether a local level of PTX3 might be a sensitive marker for the local inflammation of AF. | 23979265 |
| Inflammation, Atrial Fibrillation | Altered Intercellular Communication | These data demonstrate that local PTX3 production in the left atrium might reflect the local inflammation of AF. | 23979265 |
| Uveomeningoencephalitic Syndrome | Altered Intercellular Communication | The medical records of consecutive patients with Vogt-Koyanagi-Harada disease without active intraocular inflammation were reviewed, and one eye was randomly chosen for analyses. | 23979311 |
| Uveomeningoencephalitic Syndrome, Hypopigmentation disorder, Choroiditis | Altered Intercellular Communication | The thinner choroid and larger PPA areas were correlated with the degree of depigmentation or disease duration and might be caused by latent choroidal inflammation in the convalescent stage of Vogt-Koyanagi-Harada disease. | 23979311 |
| Inflammation | Altered Intercellular Communication | These precursors would eventually migrate into the lamina propria to differentiate into aT/cB/PC, complying thereby with the immunological mucosal demands generated by the on-going chronic inflammation. | 23979405 |
| Mesenteric Panniculitis, Inflammation, Pseudotumor | Altered Intercellular Communication | Mesenteric panniculitis represents a cronic inflammation of the adipose tissue of the mesentery which can present sometimes with the imagistic aspect of one or multiples pseudotumors. | 23979623 |
| Inflammation, Obesity | Altered Intercellular Communication | Inflammation is a potential mechanism linking obesity and cardiometabolic risk. | 23979951 |
| Inflammation | Altered Intercellular Communication | XBJ was an effective therapeutic drug capable to control the in vivo inflammation reaction in patients with ALI/ARDS. | 23980355 |
| Benign Prostatic Hyperplasia, Inflammation | Altered Intercellular Communication | To determine whether low-grade systemic inflammation is associated with prostatic enlargement/benign prostatic hyperplasia. | 23980666 |
| Inflammation, Benign prostatic hypertrophy | Altered Intercellular Communication | Chronic low-grade systemic inflammation might be involved in the etiology of benign prostatic hyperplasia. | 23980666 |
| Gingivitis, Metabolic Syndrome X, Obesity | Altered Intercellular Communication | Metabolic syndrome and gingival inflammation in Caucasian children with a family history of obesity. | 23980866 |
| Gingivitis, Metabolic Syndrome X, ETV3 wt Allele | Altered Intercellular Communication | To investigate whether metabolic syndrome (MetS) and its components are associated with gingival inflammation in children. | 23980866 |
| Inflammation, Tumor necrosis, Gingival Hemorrhage | Altered Intercellular Communication | Gingival inflammation was defined by the level of gingival crevicular fluid (GCF) tumour necrosis factor alpha (TNF-a) and the extent of gingival bleeding. | 23980866 |
| Inflammation, ETV3 wt Allele | Altered Intercellular Communication | Sex-specific linear regression analyses estimated the associations between MetS and gingival inflammation, adjusting for potential confounders. | 23980866 |
| Inflammation, ETV3 wt Allele | Altered Intercellular Communication | An association between MetS and gingival inflammation was observed as early as in childhood, and may differ by sex. | 23980866 |
| Inflammation, Spongiosis, Urticaria | Altered Intercellular Communication | Differently, in urticarial lesions, no specific features could be appreciated at confocal analysis beside the presence of signs of spongiosis and perivascular inflammation. | 23981107 |
| Inflammation, Neoplasm Metastasis | Altered Intercellular Communication | A significant correlation was seen between P53 immunoexpression and histologic grade (P = 0.047), but there was no significant correlation between P53 expression with lymph node metastasis and inflammation intensity. | 23981150 |
| Inflammation, Neoplasm Metastasis | Altered Intercellular Communication | No significant correlation between GB and P53 immunoexpression, lymph node metastasis, or inflammation intensity was seen. | 23981150 |
| Carcinogenic Chlorinated Hydrocarbon, Fibrosis Assessment, Acute inflammation | Altered Intercellular Communication | Elevated serum M30-CK18, as an indicator of enhanced apoptosis of hepatocytes, parallels active hepatic inflammation and fibrosis but also biochemical activity in CHC; thus, it may serve as a comprehensive non-invasive marker of disease activity. | 23981197 |
| glucagon, human, Inflammation, Pyogenic granuloma, Giant Cell Granuloma | Altered Intercellular Communication | All cases showed microscopic evidence for inflammation; however, although 41% exhibited only nonspecific inflammation, 29.9% exhibited actinomyces-related inflammation, 18.8% pyogenic granuloma (PG), and 10.3% giant cell granuloma (GCG). | 23981243 |
| Inflammation | Altered Intercellular Communication | Lesions with simple inflammation could not be distinguished clinically or radiographically from the potentially destructive lesions. | 23981243 |
| Inflammation, Actinomycosis | Altered Intercellular Communication | There were no clinical features which could distinguish PI with simple inflammation from potentially destructive lesions mimicking PI, such as GCG, PG, and actinomycosis. | 23981243 |
| Inflammation, Actinomycosis | Altered Intercellular Communication | However, to control GCG and PG surgical procedures would be recommended, actinomycosis would indicate specific antibiotics, whereas in nonspecific inflammation, these measures may not be indicated. | 23981243 |
| Inflammation, Hypoxia | Altered Intercellular Communication | Pathways related to inflammation, hypoxia, and stress showed activation, and pathways that play roles in neurogenesis and myelination showed decreases. | 23981442 |
| Post-Traumatic Stress Disorder, Inflammation, Depression, CTCAE | Altered Intercellular Communication | The cortisol pathway dysregulation and increased inflammation identified here are seen in other stress-related conditions such as depression and post-traumatic stress disorder and most likely play a role in addiction. | 23981442 |
| Inflammation, Metabolic Syndrome X | Altered Intercellular Communication | Correlations of ghrelin serum levels with disease activity, systemic inflammation and metabolic syndrome were assessed. | 23981480 |
| Inflammation, Primary malignant neoplasm, Cerebrovascular accident | Altered Intercellular Communication | Chronic inflammation and an activated coagulation system may contribute to the pathogenic mechanism of strokes, the extent of each depending on the activity and severity of cancer. | 23981525 |
| ARCN1 gene, Chronic Obstructive Airway Disease, Exacerbation | Altered Intercellular Communication | This increases corticosteroid-resistant airway inflammation in chronic obstructive pulmonary disease (COPD) and leads to exacerbations. | 23981542 |
| Airway structure, Bacterial Infections, Exacerbation | Altered Intercellular Communication | We conclude that HASMCs contribute to the increase in airway inflammation in COPD exacerbations caused by gram-positive bacterial infections. | 23981542 |
| Cholecystitis | Altered Intercellular Communication | Xanthogranulomatous cholecystitis (XGC) is a rare type of gallbladder inflammation. | 23981609 |
| Inflammation, Dental Plaque | Altered Intercellular Communication | The aim of the study was to determine if plaque neovascularization led to inflammation. | 23981615 |
| Inflammation | Altered Intercellular Communication | A target to background ratio (TBR) of >= 1.25 or < 1.25 served as the cutoff point for the presence and absence of inflammation, respectively. | 23981615 |
| Inflammation | Altered Intercellular Communication | This may be caused by less reduction in coronary circulatory platelet activation and inflammation. | 23981616 |
| Hepatic, Nia (fungus), Insemination, Artificial, Homologous, Autoimmune Chronic Hepatitis, Inflammatory, Traumatic injury, Waldenstrom Macroglobulinemia | Altered Intercellular Communication | Autoimmune hepatitis (AIH) after liver transplantation has been defined histologically as a "hepatitic" pattern of injury, characterized by lymphoplasmacytic inflammation with necroinflammatory activity (NIA), comparable with findings seen in native livers. | 23982338 |
| Inflammation, Cardiovascular Diseases | Altered Intercellular Communication | HIV-infected adults display increased cardiovascular disease, probably driven by inflammation and immune activation. | 23982657 |
| Postprandial Period | Altered Intercellular Communication | An Open-Label Randomized Crossover Trial of Lyophilized Black Raspberries on Postprandial Inflammation in Older Overweight Males: A Pilot Study. | 23982695 |
| Postprandial Period, Overweight | Altered Intercellular Communication | This study was a 14-day, outpatient, open-label randomized crossover trial of lyophilized black raspberries (BRBs) in older overweight or obese males to determine whether BRB consumption affects postprandial inflammation associated with consumption of a high-fat high-calorie (HFHC) meal. | 23982695 |
| Postprandial Period, Overweight | Altered Intercellular Communication | The findings of this pilot study suggest that consumption of lyophilized BRBs may attenuate postprandial inflammation in overweight or obese males consuming a HFHC meal. | 23982695 |
| Inflammation, Primary malignant neoplasm, Adenoma of large intestine | Altered Intercellular Communication | Chronic inflammation has been implicated in the etiology of colorectal adenoma and cancer; however, few key inflammatory genes mediating this relationship have been identified. | 23982929 |
| Inflammation, Colorectal Carcinoma | Altered Intercellular Communication | Additional studies on the functional consequences of rs5995355 in NCF4 may help to clarify the mechanistic link between inflammation and colorectal cancer. | 23982929 |
| Inflammation, Periodic Fever, Aphthous Stomatitis, Pharyngitis, Adenitis Syndrome, Fever, CTCAE | Altered Intercellular Communication | PFAPA syndrome is characterized by recurrent attacks of fever and symptoms of inflammation consistent with the disease acronym. | 23983059 |
| Inflammation, Aggressive behavior, Benign prostatic hypertrophy | Altered Intercellular Communication | We evaluated the correlation between tPSA, fPSa, f/t PSA ratio, cPSA, MPV and extent and aggressiveness of inflammation in the surgical specimens of patients who underwent surgery for benign prostatic hyperplasia (BPH). | 23983600 |
| Inflammation, prostatitis | Altered Intercellular Communication | MPV values may be used as an inflammation marker in patients with prostatitis. | 23983600 |
| Inflammation, Ovalocytosis, Malaysian-Melanesian-Filipino Type | Altered Intercellular Communication | LAA had a stronger activation of inflammation than SAO in the pathogenesis, which was associated with the changes of CRP. | 23983602 |
| Observation Method - Coagulation, Cardiovascular Diseases | Altered Intercellular Communication | Comparison of cardiovascular disease risk markers in HIV-infected patients receiving abacavir and tenofovir: the nucleoside inflammation, coagulation and endothelial function (NICE) study. | 23985706 |
| Inflammation, Observation Method - Coagulation | Altered Intercellular Communication | Among individuals assigned to ABC or TDF in randomized clinical trials there were no significant differences in FMD or markers of inflammation and coagulation. | 23985706 |
| Inflammation, Endothelial dysfunction | Altered Intercellular Communication | Whether ABC contributes to risk of CVD remains unclear, but our results suggest that endothelial dysfunction, heightened inflammation, and altered coagulation are unlikely to be mechanisms by which the drug could increase CVD risk above that seen with TDF. | 23985706 |
| Inflammation, Colorectal Carcinoma | Altered Intercellular Communication | Chronic inflammation has been implicated in the pathogenesis of colorectal cancer. | 23985781 |
| Inflammation, Diabetes Mellitus, Non-Insulin-Dependent, Tuberculosis, Diabetes Mellitus | Altered Intercellular Communication | Our data reveal that tuberculosis with diabetes is characterized by heightened cytokine responsiveness, indicating that chronic inflammation underlying type 2 diabetes potentially contributes to increased immune pathology and poor control in tuberculosis infection. | 23987505 |
| Inflammation, Intracranial Hypertension, Hydrocephalus, Meningitis | Altered Intercellular Communication | Cryptococcal choroid plexus inflammation is a particularly rare entity most often presenting with signs and symptoms of intracranial hypertension, hydrocephalus or meningitis due to a delayed diagnosis. | 23988229 |
| Inflammation, Congestive heart failure | Altered Intercellular Communication | Severe CSA in CHF patients is associated with elevated levels of CRP, a systemic marker of inflammation and cardiovascular risk. | 23988380 |
| Inflammation | Altered Intercellular Communication | Chronic, low grade inflammation is a characteristic of old age. | 23988651 |
| Inflammation | Altered Intercellular Communication | In summary, our data suggests that LiCl reduces inflammation in aged and young DCs via different mechanisms. | 23988651 |
| Sepsis, Inflammation, physiopathological, Hypoperfusion | Altered Intercellular Communication | Glycocalyx degradation may contribute to microvascular dysfunction and tissue hypoperfusion during systemic inflammation and sepsis. | 23988876 |
| Inflammation, Sensorineural Hearing Loss (disorder) | Altered Intercellular Communication | Recently, the cause of ISSNHL, which is still unclear, has been focused on chronic inflammation. | 23988996 |
| Airway structure | Altered Intercellular Communication | Determining the site of airways inflammation may lead to the targeting of therapy. | 23989961 |
| Refractory anemias | Altered Intercellular Communication | RA is associated with dysregulation of T-cell subsets (naive, regulatory (Treg) and inflammation-related cells (IRC)) early in the disease. | 23989988 |
| Inflammation, Primary malignant neoplasm | Altered Intercellular Communication | Higher religion scores were associated with lower levels of inflammation in advanced cancer patients still undergoing ANTs. | 23990104 |
| Sepsis | Altered Intercellular Communication | Immune activation is a regular feature of sepsis, but the incidence and nature of the ensuing inflammation-resolving and immunosuppressive component is less well understood. | 23990136 |
| Ischemic stroke | Altered Intercellular Communication | Inflammation-induced catabolism of tryptophan and tyrosine in acute ischemic stroke. | 23990339 |
| Adrenocortical, Neoplasm, uncertain whether benign or malignant | Altered Intercellular Communication | Adrenocortical oncocytoma of borderline malignant potential with high FDG uptake may require long-term follow-up with clinical, hormonal, and imaging evaluations. | 23990396 |
| Infection caused by Onchocerca, Inflammation | Altered Intercellular Communication | All of the previously reported cases of O. lupi in both humans and dogs were more symptomatic than in our patient, Onchocerca infection should not be ruled out during the differential diagnosis of the subconjunctival and orbital cystic mass in instances where there is little to no inflammation. | 23990437 |
| Chronic kidney disease stage 5, Communicable Diseases, Inflammation, Chronic Kidney Diseases | Altered Intercellular Communication | Although procalcitonin (PCT) has been described as a marker of infection and inflammation, it has not been extensively studied in patients with chronic kidney disease (CKD), end stage renal disease, or renal transplant. | 23990496 |
| Inflammation, PLAU protein, human | Altered Intercellular Communication | Urokinase-type plasminogen activator receptor is a multifunctional glycoprotein, the expression of which is increased during inflammation. | 23990945 |
| Chronic lymphocytic inflammation, Lupus Erythematosus | Altered Intercellular Communication | Typical histologic features of cutaneous lupus, such as follicular plugging, angiocentric lymphocytic inflammation, and dermal mucin, are very helpful clues to the diagnosis of hypertrophic lupus erythematosus. | 23991731 |
| Inflammation, Observation Method - Coagulation, Traumatic injury | Altered Intercellular Communication | A2AP deficiency further was associated with exaggerated systemic inflammation and coagulation, increased distant organ injury, and enhanced lethality. | 23992406 |
| Periarticular Route of Administration | Altered Intercellular Communication | Imaging revealed articular or periarticular inflammation in many cases and bone lesions near 22% of affected joints. | 23992800 |
| Inflammation, Atherosclerosis of aorta | Altered Intercellular Communication | The present work favors a role for coinfection of both M pneumoniae and C pneumoniae in the development of aortic atherosclerotic aneurysm, with increased adventitial inflammation, inhibition of TIMP-1 activity, and increased collagen degradation. | 23993112 |
| Peripheral ulcerative keratitis, Inflammation | Altered Intercellular Communication | Peripheral ulcerative keratitis (PUK) is a sight-threatening condition characterized by an epithelial defect, crescent-shaped stromal inflammation, and progressive stromal thinning. | 23993305 |
| Sarcoidosis | Altered Intercellular Communication | We describe a case report of PUK associated with the inflammatory condition of sarcoidosis. | 23993305 |
| Hepatitis, Communicable Diseases, Keratitis, Syphilis, Fungal keratitis, Keratitis, Herpetic, "Moorens ulcer | Altered Intercellular Communication | PUK can also be associated with infectious and inflammatory conditions such as hepatitis, syphilis, herpes simplex keratitis, fungal keratitis, Mooren ulcer, and marginal keratitis. | 23993305 |
| Inflammation, Neuropathologist, "Alzheimers Disease", Tumor necrosis, senile | Altered Intercellular Communication | Alzheimer's disease is neuropathologically characterized by the accumulation of amyloid-b protein into senile plaques that are sites of chronic inflammation involving reactive microglia, astrocytes, and proinflammatory molecules, such as interleukin-1b and tumor necrosis factor-a. | 23993701 |
| Inflammatory disorder | Altered Intercellular Communication | The human CCAAT/enhancer-binding protein (CEBP) delta (CEBPD) is known to be induced in many inflammation-related diseases. | 23993701 |
| Inflammation, Osteolysis | Altered Intercellular Communication | We aimed to characterize the unknown pathophysiological effects of APN on wear particle-induced inflammation, apoptosis and osteolysis. | 23994269 |
| Inflammation, Osteolysis | Altered Intercellular Communication | Osteolysis and inflammation were quantified by histomorphometry and microcomputed tomography, apoptosis by immunohistochemistry and TUNEL assay. | 23994269 |
| Osteolysis | Altered Intercellular Communication | Administration of APN in mice significantly reduced wear particle-induced inflammation, osteolysis and the number of caspase-3-positive macrophages. | 23994269 |
| Communicable Diseases, Inflammation | Altered Intercellular Communication | Infection was the most common cause of LR (n = 83, 47.9%; 95% confidence interval, 40.7-55.4), followed by ischemia/stress (27.7%), inflammation (6.9%), and obstetric diagnoses (6.9%). | 23994818 |
| Inflammation, Infection | Altered Intercellular Communication | LR was found to have multiple etiologies including infections, stress, inflammation, and obstetric diagnoses. | 23994818 |
| Infection caused by Helicobacter pylori, Malignant neoplasm of gastrointestinal tract, Chronic gastritis | Altered Intercellular Communication | Epidemiological investigations indicated association of the Helicobacter pylori infections with the occurrence of inflammatory conditions of the gastric mucosa and development of chronic gastritis and intestinal type of gastric cancer. | 23995914 |
| Hypertensive disease, Inflammation, Refractory anemias | Altered Intercellular Communication | We examined the hypothesis that mediators of inflammation and markers of cardiovascular risk are associated with HTN in RA. | 23996293 |
| Hypertensive disease, Inflammation, Refractory anemias | Altered Intercellular Communication | HTN in patients with RA is not associated with generalized systemic inflammation or insulin resistance, but is associated with increasing concentrations of homocysteine and leptin. | 23996293 |
| allergic inflammation, Chronic sinusitis | Altered Intercellular Communication | It seemed that aspirin had positive effects in allergic inflammation at least in some subset of aspirin tolerant patients with chronic sinusitis. | 23996718 |
| Pneumonia, Lipid, Pneumonitis | Altered Intercellular Communication | Lipoid pneumonia (LP) is a chronic inflammation of the lung parenchyma with interstitial involvement due to the accumulation of endogenous or exogenous lipids. | 23996884 |
| Airway structure | Altered Intercellular Communication | Fractional exhaled nitric oxide (FeNO) measurement is an important noninvasive tool for evaluating eosinophilic inflammation of the airways. | 23998240 |
| Damage | Altered Intercellular Communication | Human mesenchymal stem/stromal cells (hMSCs) have been reported to improve neural damage via anti-inflammation and multi-differentiation abilities. | 23998421 |
| Pain Distress Question, Varicose Ulcer, Inflammation, Depression, CTCAE | Altered Intercellular Communication | Patients with venous leg ulcers experience multiple symptoms, including pain, depression, and discomfort from lower leg inflammation and wound exudate. | 23998779 |
| Pain Distress Question, Inflammation, Dyssomnias, Exudate, Swelling, Depression, CTCAE, Fatigue | Altered Intercellular Communication | Exploratory factor analysis identified two symptom clusters: pain, depression, sleep disturbance, and fatigue; and swelling, inflammation, exudate, and fatigue. | 23998779 |
| Airway structure | Altered Intercellular Communication | Given previous evidence that exhaled isoprene is elevated in systemic inflammatory states, we hypothesized that exhaled isoprene would be positively associated with a breath biomarker of airway inflammation, the fractional concentration of exhaled nitric oxide (FENO). | 23999846 |
| Inflammation, Fibrosis Assessment | Altered Intercellular Communication | Liver biopsy showed patchy advanced fibrosis, mild inflammation, positive staining for copper, and a tissue copper concentration of 768 ug/g (10-35 mg/g). | 23999958 |
| Inflammation, Intradermal Route of Drug Administration | Altered Intercellular Communication | In adult CF patients iron deficiency (ID) is common and primarily functional due to chronic inflammation. | 24000193 |
| Inflammation, Lung diseases | Altered Intercellular Communication | Over the last decades onset of inflammation and pulmonary disease in children with CF is delayed by improved nutritional status. | 24000193 |
| Inflammation | Altered Intercellular Communication | Higher Fer values found in older children represent an increased state of inflammation, rather than an improved iron status, and might increase the relative contribution of functional ID. | 24000193 |
| Inflammation, Muscle Strength, Hyperuricemia | Altered Intercellular Communication | However, several studies have demonstrated that hyperuricemia is closely related to systemic inflammation and has oxidant properties effects, both of which may increase the risk of muscle strength loss. | 24000893 |
| Inflammation, LATS1 gene, Traumatic injury | Altered Intercellular Communication | The external examination revealed multiple warts in the perianal region, but no lesions, discharge, inflammation, or external signs of trauma were visible. | 24001431 |
| Inflammation, Tuberculous osteomyelitis | Altered Intercellular Communication | A 71-yr-old man presented with inflammation in the left elbow and he underwent a surgery under the suspicion of tuberculous osteomyelitis. | 24003427 |
| Inflammation, Arteriosclerosis, Autoimmune Diseases, Infection, Connective Tissue, Colagenosis, Disease | Altered Intercellular Communication | netic factors, infections, disorders in connective tissue (collagenosis), arteriosclerosis, inflammation, incorrect immune response (autoimmunity). | 24003660 |
| Inflammation, Blood Clot, Dental Plaque, Angina Pectoris | Altered Intercellular Communication | In conclusion, culprit lesions in STEMI patients showed a greater plaque burden, remodeling index, and more frequent thrombi with increased inflammation and neovascularization compared to the stable angina group, supporting the current concept of vulnerable plaques being responsible for STEMI. | 24005982 |
| Inflammation, Hyperplasia, Cervical Intraepithelial Neoplasia | Altered Intercellular Communication | Vascularization was combined in all eyes with SCC, in two of eight (25%) with CIN, in two of three with inflammation, and in none with hyperplasia. | 24006080 |
| Inflammation, Hyperplasia, Cervical Intraepithelial Neoplasia | Altered Intercellular Communication | Both cornea and conjunctiva were involved in ten of 11 eyes (90.9%) with SCC, in six of eight (75%) with CIN, in two of eight (25%) with hyperplasia, and in two of three (66.7%) with inflammation. | 24006080 |
| Inflammation, Hyperplasia | Altered Intercellular Communication | Hyperplasia or lesions with inflammation did not recur. | 24006080 |
| Hepatic inflammation, FAM126A gene | Altered Intercellular Communication | We hypothesized that long-term iron deficiency could attenuate the hepatic inflammation and lead to a lower incidence of HCC in India than expected. | 24006121 |
| Inflammation, Peripheral Arterial Diseases | Altered Intercellular Communication | Impaired vascular endothelial growth factor A and inflammation in patients with peripheral artery disease. | 24006146 |
| Inflammation, Peripheral Arterial Diseases, GDC Comorbidity Terminology | Altered Intercellular Communication | We compared apoptosis, cellular oxidative stress, and inflammation of cultured endothelial cells treated with sera from 130 patients with peripheral artery disease (PAD) and a control group of 36 patients with high burden of comorbid conditions and cardiovascular risk factors. | 24006146 |
| Additional | Altered Intercellular Communication | Additional alterations in phosphoproteins suggests dysregulation of mitochondria, synaptic transmission, vesicle trafficking, and innate immune pathways. | 24006891 |
| Inflammation, Muscle of orbit | Altered Intercellular Communication | Eyes with a clinical VISA inflammation score of <= 4 had an average extraocular muscle SUVmax of 3.09, and those with a score of >= 5 had an average SUVmax of 3.92 (P = 0.09), showing no clear correlation between clinically observed inflammation and 18-FDG uptake. | 24007404 |
| Inflammation, Muscle of orbit | Altered Intercellular Communication | We demonstrated a lack of correlation between 18-FDG extraocular muscle uptake and either clinical inflammation score or muscle diameter. | 24007404 |
| Uveitis | Altered Intercellular Communication | Incidence and prevalence of uveitis: results from the Pacific Ocular Inflammation Study. | 24008391 |
| Malnutrition | Altered Intercellular Communication | The time-averaged serum bacterial DNA level significantly correlated with malnutrition inflammation score (r = 0.550, p = 0.008) and inversely with subjective global assessment score (r = -0.543, p = 0.009), but not with PWV. | 24008429 |
| Inflammation, Vascular Stiffness | Altered Intercellular Communication | In hemodialysis patients, circulating endotoxin level is associated with vascular stiffness and systemic inflammation. | 24008429 |
| Inflammation | Altered Intercellular Communication | We suggest the use of this ratio for the assessment of aortic inflammation in GCA patients. | 24008434 |
| Inflammation, Hydronephrosis, Adenocarcinoma, Urolithiasis, Intestinal metaplasia | Altered Intercellular Communication | Although their pathogenesis is not well defined, adenocarcinomas are likely to originate from neoplastic transformation of the glandular cells of the urothelial intestinal metaplasia usually arising in response to chronic irritating stimuli, such as long-duration inflammation, urolithiasis, and hydronephrosis. | 24008439 |
| Tubulovillous adenoma, Primary malignant neoplasm, Inflammation, Adenocarcinoma, Adenoma, Villous, Intestinal metaplasia | Altered Intercellular Communication | Histological examination disclosed an infiltrating adenocarcinoma arising from a tubulovillous adenoma with the surrounding pelvic mucosa showing a sequence of intestinal metaplasia, low- and high-grade villous adenoma, and invasive adenocarcinoma, supporting the hypothesis of cancer progression due to chronic inflammation from the urothelium through the metaplasia step. | 24008439 |
| Inflammation, Infection caused by Helicobacter pylori, Mucosa-Associated Lymphoid Tissue Lymphoma | Altered Intercellular Communication | Chronic inflammation, such as Helicobacter pylori infection, is considered to be a cause of MALT lymphoma. | 24008643 |
| Inflammation, Colorectal Carcinoma | Altered Intercellular Communication | We analysed the densities of eight types of inflammatory cells in a prospectively recruited group of 117 CRC patients and determined their interrelationships and contributions to Klintrup-Makinen (K-M) score of overall peritumoural inflammation. | 24008661 |
| Inflammation, Kidney Failure | Altered Intercellular Communication | Systemic inflammation, as evidenced by elevated inflammatory cytokines, is a feature of advanced renal failure and predicts worse survival. | 24009237 |
| Inflammation, Comorbidity | Altered Intercellular Communication | After adjustment for multiple covariates, systemic inflammation was associated with age and comorbidity and independently predicted patient survival in both incident and prevalent cohorts. | 24009237 |
| Kidney Failure, Chronic, Inflammation | Altered Intercellular Communication | Few studies have examined the changes in lipoproteins over time and how inflammation is associated with lipoprotein concentrations among patients with end-stage renal disease on dialysis. | 24009290 |
| Inflammation | Altered Intercellular Communication | Changes in inflammatory markers were associated with changes in apo A1, but not apo B over 1 year, suggesting that reductions in high-density lipoprotein cholesterol are associated with inflammation, either of which could mediate cardiovascular risk, but not supporting a hypothesis linking increased risk of low levels of apo B containing lipoproteins to the risk associated with inflammation. | 24009290 |
| Inflammation, Polyneuropathy | Altered Intercellular Communication | Association of subclinical inflammation with polyneuropathy in the older population: KORA F4 study. | 24009302 |
| Adrenal incidentaloma | Altered Intercellular Communication | Based on these findings, initial hormonal and radiographic evaluations for adrenal incidentalomas appear to be more important than follow-up tests because functional or malignant changes are rare. | 24009451 |
| Inflammation, SLC25A20 gene, Atherosclerosis | Altered Intercellular Communication | These results demonstrate that the degree of chronic adaptive immune activation is associated with both CAC and CC IMT in otherwise healthy individuals, consistent with the known role of CD4(+) T cells, and with innate immunity (inflammation), in atherosclerosis. | 24009662 |
| Inflammation, Atherosclerosis, Arteritis | Altered Intercellular Communication | As atherosclerosis is a disease characterized by chronic arterial inflammation, it is possible that moderate increases in CRP level reflect the presence of plaque inflammation. | 24010553 |
| Inflammation, Dental Plaque | Altered Intercellular Communication | To investigate this possibility, we compared plasma levels of hsCRP the day before carotid endarterectomy with the degree of inflammation in the excised plaque tissue. | 24010553 |
| Inflammation | Altered Intercellular Communication | The present findings strongly argue against hsCRP as a marker of plaque inflammation. | 24010553 |
| Inflammation, Cardiovascular Diseases | Altered Intercellular Communication | Hence, it is more likely that elevated hsCRP is a sign of a subclinical systemic inflammation and this in turn may contribute to progression of cardiovascular disease. | 24010553 |
| Inflammation, Metabolic Syndrome X, ETV3 wt Allele, Chronic Kidney Diseases | Altered Intercellular Communication | We investigated the relationships between dietary fat quality, the metabolic syndrome (MetS), insulin sensitivity and inflammation in individuals with CKD. | 24011327 |
| Inflammation, ETV3 wt Allele, Chronic Kidney Diseases | Altered Intercellular Communication | A serum fatty acid pattern reflecting low LA and high SFA was strongly associated with MetS, IR and inflammation in two independent surveys of elderly individuals with CKD. | 24011327 |
| Inflammation, Acne | Altered Intercellular Communication | Acne is a common disorder of the human pilosebaceous unit, yet the mechanisms underlying hyperkeratinisation and subsequent inflammation (comedogenesis) remain to be determined, although cutaneous pathogens are implicated. | 24011352 |
| Inflammation, Diabetes Mellitus, Non-Insulin-Dependent, Chronic Kidney Diseases | Altered Intercellular Communication | Association of biomarkers of inflammation and oxidative stress with the risk of chronic kidney disease in Type 2 diabetes mellitus in North Indian population. | 24012111 |
| Inflammation, Damage, diabetic | Altered Intercellular Communication | increased MDA and decreased GSH and FRAP in DM-CKD suggest an important role of inflammation and oxidative stress in the pathogenesis of renal damage in diabetic patients. | 24012111 |
| Inflammation, Cachexia | Altered Intercellular Communication | Cancer cachexia is associated with impaired nutritional status and systemic inflammation. | 24012284 |
| Malignant neoplasm of esophagus, Inflammation | Altered Intercellular Communication | Impaired nutrition status, elevated energy expenditure, and higher inflammation status tend to be apparent in weight-losing patients with newly diagnosed esophageal cancer, which suggested that early recognition of body weight change and routine nutritional risk screening followed by adequate nutrition intervention should be applied in these patients. | 24012284 |
| Kit Ligand, human | Altered Intercellular Communication | Although within the normal range, the increased numbers of WBCs and neutrophils in patients with SCF suggest that SCF may be a subclinical inflammatory condition. | 24012331 |
| Neoplasms | Altered Intercellular Communication | Recruitment of immune cells to tumors is a complex process crucial for both inflammation-driven tumor progression and specific anti-tumor cytotoxicity. | 24013383 |
| Communicable Diseases, Inflammation, Neoplasms | Altered Intercellular Communication | The accuracy of CT-guided CNB for specific diagnosis of benign soft-tissue tumours as well as infection and inflammation was relatively low. | 24014785 |
| Inflammation, Colorectal Carcinoma | Altered Intercellular Communication | Chronic inflammation is thought to be the leading cause of colorectal cancer, and interleukin-10 (IL10) has been identified as a potent immunomodulatory cytokine that regulates inflammatory responses in the gastrointestinal tract. | 24015034 |
| Inflammation, Diabetes Mellitus, Cardiovascular Diseases | Altered Intercellular Communication | Chemical modification of apoA-I, as may occur under conditions of inflammation or diabetes, can severely impair HDL function and is associated with the presence of cardiovascular disease. | 24015188 |
| Necrotizing granulomatous inflammation, Hemorrhage | Altered Intercellular Communication | A second biopsy revealed chronic granulomatous dermal inflammation and hemorrhage with foreign body giant cells non-infectious by stains. | 24015784 |
| HSPG2 wt Allele, Inflammation, Necrosis | Altered Intercellular Communication | SJS is a rare and acute, self-limited disease, characterized by severe inflammation and necrosis of two or more mucous membranes. | 24016288 |
| Inflammation, Vascular Invasion Assessment, FAM126A gene | Altered Intercellular Communication | We suggest that inflammation of hepatic microenvironment promote pathological degradation and microvascular invasion of HCC. | 24018067 |
| Inflammation, Demyelination, Experimental Autoimmune Encephalomyelitis, Nerve Degeneration | Altered Intercellular Communication | ASCs from older donors failed to ameliorate the neurodegeneration associated with EAE, and mice treated with older donor cells had increased central nervous system inflammation, demyelination, and splenocyte proliferation in vitro compared with the mice receiving cells from younger donors. | 24018793 |
| Inflammation | Altered Intercellular Communication | Laboratory investigations revealed an inflammation with increased C-reactive protein, elevated erythrocyte sedimentation rate and neutrophil count. | 24021028 |
| Inflammatory abnormality of the eye | Altered Intercellular Communication | The primary efficacy end point was cleared ocular inflammation, as measured by the summed ocular inflammation score of zero (anterior chamber cell count = 0 and absence of flare) by day 15. | 24021896 |
| Pain Distress Question, Inflammatory abnormality of the eye | Altered Intercellular Communication | Secondary end points included cleared ocular inflammation at day 15 and the number of subjects who were pain free at day 1. | 24021896 |
| Inflammatory abnormality of the eye | Altered Intercellular Communication | A significantly higher proportion of subjects treated with bromfenac 0.07% achieved complete clearance of ocular inflammation by day 15 and at day 15 compared with placebo (P < 0.0001). | 24021896 |
| Cataract, Pain Distress Question, Inflammatory abnormality of the eye | Altered Intercellular Communication | Bromfenac ophthalmic solution 0.07% dosed once daily was clinically safe and effective compared with placebo for the treatment of ocular inflammation and pain in subjects who had undergone cataract surgery and may be a beneficial addition to the current standard of care, which commonly includes ophthalmic antibiotics and corticosteroids. | 24021896 |
| Inflammation, Macular Edema, Cystoid, Papilledema, Periphlebitis | Altered Intercellular Communication | Examination revealed mild anterior chamber inflammation, optic disc swelling, cystoid macular edema and periphlebitis in both eyes. | 24022644 |
| Tinnitus, Sensorineural Hearing Loss (disorder), Headache, Inflammatory abnormality of the eye | Altered Intercellular Communication | About 6 months after subsequent treatment with an oral corticosteroid started, headache, tinnitus, and sensorineural hearing loss developed, and increased choroidal thickness was observed without other evidence of increased ocular inflammation. | 24022645 |
| Inflammation, Fibrosis Assessment, Edema | Altered Intercellular Communication | Endoscopic resection (ER) causes inflammation, edema, fibrosis of the stomach, and severe adhesions around the surrounding tissue. | 24023345 |
| Inflammation, Ischemic stroke | Altered Intercellular Communication | Inflammation exists in inception, progression, and reperfusion of acute ischemic stroke. | 24023414 |
| Inflammation, Fever, CTCAE, Epithelial, Acute Lung Injury, Endothelial dysfunction | Altered Intercellular Communication | Acute lung injury (ALI) is characterized by inflammation, leukocyte activation, neutrophil recruitment, endothelial dysfunction, and epithelial injury, which are all affected by fever. | 24024608 |
| Fat-Free Diet, vascular inflammations | Altered Intercellular Communication | In summary, TRP in fat-free milk may provide cardiovascular benefits beyond that of fPS by inducing more substantial decreases in LDL cholesterol and particle concentration, associated with declines in markers of vascular inflammation. | 24024768 |
| Sepsis, Inflammation | Altered Intercellular Communication | Systemic endotoxin activity correlates with clot formation: an observational study in patients with early systemic inflammation and sepsis. | 24025340 |
| Inflammation, Observation Method - Coagulation | Altered Intercellular Communication | Inflammation and coagulation are closely linked, and both can be triggered by endotoxin. | 24025340 |
| Pain Distress Question, Inflammation, Sleep-Disordered Breathing, Sleep Fragmentation, Hypoxemia | Altered Intercellular Communication | On the basis of experimental and clinical evidence, the authors hypothesized that nocturnal hypoxemia would be associated with pain reports in subjects suffering from sleep-disordered breathing, independently of sleep fragmentation and inflammation. | 24025612 |
| Pain Distress Question, Sleep Fragmentation, Inflammation, Sleep-Disordered Breathing | Altered Intercellular Communication | Nocturnal arterial desaturation may be associated with an increased pain in subjects with sleep-disordered breathing, independently of sleep fragmentation and inflammation. | 24025612 |
| Inflammation | Altered Intercellular Communication | Ontology and pathway analyses showed inflammation as the principal biological function associated with these miRNAs. | 24025639 |
| Glomerulitis (disorder), Interstitial inflammation, Tubulitis Assessment, Infiltration, Intimal Arteritis Assessment | Altered Intercellular Communication | Pathological findings favoring AMR (PTC infiltration and glomerulitis) showed a greater risk of DSC compared with those favoring CMR (interstitial inflammation, intimal arteritis, and tubulitis). | 24025693 |
| Inflammation, Discitis | Altered Intercellular Communication | 18F-FDG-PET is therefore an important tool in inflammation imaging and can be used in the diagnostic cascade of difficult cases with suspected spondylodiscitis. | 24025917 |
| Inflammation, Liver Cirrhosis | Altered Intercellular Communication | This study shows that chronic inflammation plays a role in impaired HRQL in patients with cirrhosis irrespective of minimal HE. | 24025977 |
| Inflammation, Diabetes Mellitus | Altered Intercellular Communication | Diabetes damages major organ systems through disrupted glycemic control and increased inflammation. | 24026562 |
| Inflammation, Liver carcinoma, FAM126A gene | Altered Intercellular Communication | Neutrophil-to-lymphocyte ratio (NLR), an inflammation index, is considered a prognostic predictor of hepatocellular carcinoma (HCC). | 24026659 |
| Inflammation, Neoplasms | Altered Intercellular Communication | STAT3 in epithelial cells regulates inflammation and tumor progression to malignant state in colon. | 24027425 |
| Inflammation, Neoplasms, Colorectal Carcinoma, Malignant Neoplasms | Altered Intercellular Communication | Chronic inflammation is an important risk factor for the development of colorectal cancer; however, the mechanism of tumorigenesis especially tumor progression to malignancy in the inflamed colon is still unclear. | 24027425 |
| Neoplasms | Altered Intercellular Communication | Our data suggest that epithelial STAT3 plays a critical role in inflammation-induced tumor progression through regulation of leukocytic recruitment especially the infiltration of Treg cells in the large intestine. | 24027425 |
| Inflammation, Structure of achilles tendon, Abnormal degeneration | Altered Intercellular Communication | In the radiological study, 27 of the 52 MRI showed signs of Achilles tendon inflammation and/or degeneration, and the PF was 3.43 +- 0.48 mm thick (99%CI and SD = 0.95), as opposed to 2.09 +- 0.24 mm (99%CI, SD = 0.47) in the patients in which the MRI revealed no Achilles tendon diseases; this difference in thickness of 1.29 +- 0.57 mm (99%CI) was statistically significant (P < 0.001). | 24028383 |
| Inflammation, Chronic Kidney Diseases | Altered Intercellular Communication | Does decreased mean platelet volume predict inflammation in chronic renal failure, dialysis, and transplanted patients? | 24028675 |
| Inflammation, "Alzheimers Disease", Data types - Address | Altered Intercellular Communication | Blood-based anti-amyloid-b (Ab) immunoglobulins (IgGs) and peripheral inflammation are factors correlating with development of Alzheimer's disease (AD). | 24028868 |
| Inflammation, Data types - Address | Altered Intercellular Communication | The differences observed between genders prior to the onset of AD may indicate a lower ability in females to suppress peripheral inflammation, which may lead to exacerbated disease progression. | 24028868 |
| Myelitis, Paraplegia, Illness (finding) | Altered Intercellular Communication | We describe a case of severe brainstem and spinal cord inflammation with paraplegia and sphincter involvement in a 48 year old woman following recovery from a Pf malarial illness. | 24029237 |
| Inflammation, Endothelial dysfunction | Altered Intercellular Communication | Vascular risk factors, and markers of inflammation and endothelial dysfunction predicted lower performance in several cognitive domains. | 24029412 |
| Inflammation, Impaired cognition, Endothelial dysfunction | Altered Intercellular Communication | These findings suggest that inflammation and endothelial dysfunction might play a role in the predementia cognitive impairment stages. | 24029412 |
| Histoplasmosis | Altered Intercellular Communication | Organ transplantation and increasing use of immunosuppressive agents for chronic inflammatory conditions in non-HIV patients now account for most of the cases of histoplasmosis. | 24029651 |
| Inflammation, Metabolic Syndrome X, Obesity | Altered Intercellular Communication | We observed no evidence that obesity contributed to a decline in IQ, even among obese individuals who displayed evidence of the metabolic syndrome and/or elevated systemic inflammation. | 24029684 |
| Pituitary Neoplasms, Cerebrovascular accident | Altered Intercellular Communication | The hormonal and imaging data suggested that silent apoplexy of pituitary tumor led to spontaneous remission of CS. | 24030190 |
| Inflammation, Cardiac complication | Altered Intercellular Communication | Excess visceral fat is associated with chronic systemic inflammation and cardiovascular complications. | 24030946 |
| Inflammation, Neoplasm Metastasis | Altered Intercellular Communication | CXCL12 and its unique receptor CXCR4, play important roles in inflammation and cancer metastasis. | 24032722 |
| HMGCL gene, Inflammation, Hodgkin Disease, Lymphatic Vessel Tumors | Altered Intercellular Communication | Hodgkin lymphoma (HL) is a rare neoplasm of the lymphatic system, in which inflammation and allelic variants in cytokines have been proposed as etiological factors. | 24033107 |
| Airway structure, Inflammation, Exacerbation, myocardial injury | Altered Intercellular Communication | To investigate how COPD exacerbations and exacerbation frequency impact cardiovascular risk and myocardial injury, and whether this is related to airway infection and inflammation. | 24033321 |
| Arterial Stiffness, Inflammation | Altered Intercellular Communication | Increases in arterial stiffness are related to inflammation, and are slow to recover. | 24033321 |
| Perifolliculitis | Altered Intercellular Communication | The overall prevalence of trachomatous inflammation-follicular (TF) in children aged 1-9 years was 3.8% (95% CI 2.5-5.6), and the overall prevalence of trichiasis in adults aged >=15 years was 0.46% (95% CI 0.17-1.14). | 24033501 |
| Inflammation | Altered Intercellular Communication | Serum Helicobacter pylori CagA antibody titer as a useful marker for advanced inflammation in the stomach in Japan. | 24033876 |
| Inflammatory disease of mucous membrane | Altered Intercellular Communication | Serum CagA antibody titer was also significantly correlated with mucosal inflammation in the corpus (P = 0.04). | 24033876 |
| Airway structure, Lung diseases | Altered Intercellular Communication | Exhaled nitric oxide (NO) is a noninvasive biomarker of airway inflammation in pulmonary diseases. | 24033943 |
| Airway structure, ARCN1 gene | Altered Intercellular Communication | The role of exhaled H2S in airway inflammation in COPD still needs further investigation. | 24033943 |
| Inflammation, Dental Plaque | Altered Intercellular Communication | Furthermore, at sites with similar amounts of plaque, less clinical signs of gingival inflammation were observed in the Magnolia group than in the control group. | 24034670 |
| Malignant neoplasm of urinary bladder, Inflammation, Neoplasms | Altered Intercellular Communication | Treatment of muscle-invasive bladder cancer with chemotherapy results in haemorrhagic inflammation, mimicking residual tumour on conventional MR images and making interpretation difficult. | 24034835 |
| Spinal rigidity, Arthritis, Inflammation, Spondylitis | Altered Intercellular Communication | Ankylosing spondylitis is a chronic immune-mediated inflammatory disease characterised by spinal inflammation, progressive spinal rigidity, and peripheral arthritis. | 24035250 |
| Inflammation, Sarcoidosis, Carcinoma of lung | Altered Intercellular Communication | Of 59 eligible patients, 41 patients had TB, 5 had lung cancer, 7 had inflammation, and 6 had sarcoidosis. | 24035300 |
| Inflammation | Altered Intercellular Communication | The MAR was independently and significantly inversely associated with CRP, suggesting diet is associated with the regulation of inflammation. | 24035460 |
| Inflammation, Hypertension, CTCAE | Altered Intercellular Communication | The association between smoking quantity and hypertension mediated by inflammation in Chinese current smokers. | 24036901 |
| Inflammation, Hypertension, CTCAE | Altered Intercellular Communication | Previous studies indicated that cigarette smokers were more likely to develop hypertension, and both smoking and hypertension were associated with inflammation. | 24036901 |
| Inflammation | Altered Intercellular Communication | SIRT1 negatively regulates amyloid-beta-induced inflammation via the NF-kB pathway. | 24036938 |
| methyldopa, Inflammation | Altered Intercellular Communication | Chronic inflammation induced by amyloid-beta (Ab) plays a key role in the development of age-related macular degeneration (AMD), and matrix metalloproteinase-9 (MMP-9), interleukin (IL)-6, and IL-8 may be associated with chronic inflammation in AMD. | 24036938 |
| Retinal Degeneration, Inflammation, methyldopa | Altered Intercellular Communication | Our findings suggest a protective role for SIRT1 signaling in Ab-dependent retinal degeneration and inflammation in AMD. | 24036938 |
| Inflammation, Fibrosis Assessment | Altered Intercellular Communication | These were compared with location-matched histopathological grading of inflammation (AIS) and fibrosis (FS) using Spearman correlation, Kruskal-Wallis and Chi-squared tests. | 24037299 |
| Inflammation, Fibrosis Assessment | Altered Intercellular Communication | * Several MRI parameters correlate with inflammation and fibrosis scores from histopathology. | 24037299 |
| Structure of posterior cerebral artery, Infection, Sexually Transmitted Diseases, prostatitis | Altered Intercellular Communication | Number of sexual partners and a history of sexually transmitted infections (STIs) have been positively associated with PCa risk, and these associations may be related to pathogen-induced chronic prostatic inflammation. | 24037734 |
| prostatitis, Structure of posterior cerebral artery | Altered Intercellular Communication | These findings support a hypothesized biological mechanism whereby prostatic infection/inflammation may enhance risk of PCa. | 24037734 |
| Inflammation, Myositis | Altered Intercellular Communication | Seventy percent were inflammatory myopathies, and 2 had focal inflammation in the muscle. | 24037820 |
| Inflammation, Psoriasis, Myopathy | Altered Intercellular Communication | Myopathy or inflammation in muscle affects an average of 1.32 of every 1000 psoriasis patients. | 24037820 |
| Hypoglycemia, Neurotransmitters | Altered Intercellular Communication | OBJECTIVE/CONTEXT: Long-fasting hypoglycemia in children may be induced by neurotransmitter disorders. | 24037885 |
| Hypoglycemia, Neurotransmitters | Altered Intercellular Communication | Thus, neurotransmitter disorders should be considered in any patients presenting hypoglycemia with urine excretion of vanillactic acid. | 24037885 |
| Inflammation, Fibrosis Assessment, Fatty degeneration | Altered Intercellular Communication | Liver biopsies from 63 C282Y homozygous patients were assessed for hepatic iron concentration (HIC) and graded for iron loading, fibrosis stage, steatosis, and inflammation. | 24037895 |
| Inflammation, MDFIC gene, GDC Disease Response Terminology | Altered Intercellular Communication | HIC, age, hepatocyte senescence and proliferation, portal inflammation, and excessive alcohol consumption all had significant associations with the extent of the DR. | 24037895 |
| Inflammation, GDC Disease Response Terminology, Fibrosis Assessment, replication fork arrest, Portal inflammation | Altered Intercellular Communication | In multivariate analysis, iron loading, hepatocyte replicative arrest, and portal inflammation remained independently and significantly associated with the DR. Of factors associated with fibrosis progression, the DR (odds ratio [OR] 10.86 P<0.0001) and the presence of portal inflammation (OR 4.31, P=0.028) remained significant after adjustment for cofactors. | 24037895 |
| Inflammation, Hemochromatosis, Fibrosis Assessment, GDC Disease Response Terminology | Altered Intercellular Communication | Portal inflammation occurs in hemochromatosis and is independently associated with the DR and fibrosis, and thus its role in this disease should be evaluated further. | 24037895 |
| Inflammation, Hemorrhage, Necrosis, Liver damage, Cholestasis | Altered Intercellular Communication | Liver histology from 128 patients presenting with hepatocellular injury had more severe inflammation, necrosis, and apoptosis and more frequently demonstrated lobular disarray, rosette formation, and hemorrhage than those with cholestasis. | 24037963 |
| Inflammation, Edema | Altered Intercellular Communication | In these discrepant cases, lung sections showed significant inflammation and edema, likely accounting for increased wet lung weight. | 24039222 |
| Inflammation | Altered Intercellular Communication | To compare the mucosal concentrations of 5-aminosalicylic acid (5-ASA) resulting from different pharmaceutical formulations and analyse the influence of inflammation on the mucosal concentrations. | 24039359 |
| Inflammation | Altered Intercellular Communication | Similar results were obtained when we compared patients with the histological appearance of remission and patients with active histological inflammation (67.53 +- 9.22 ng/mg vs 35.53 +- 5.63 ng/mg, P < 0.001). | 24039359 |
| Dual-affinity B7-H3/CD3-targeted Protein MGD009, Inflammation, Meibomian gland dysfunction | Altered Intercellular Communication | The inflammation seen in meibomian gland dysfunction (MGD) is part of its pathogenesis, and evidence of the antioxidant-inflammatory properties of omega-3 fatty acids suggests this to be an appropriate treatment for MGD. | 24039409 |
| Inflammation, Cerebrovascular accident | Altered Intercellular Communication | C-reactive protein (CRP) is a biomarker of inflammation and a sensitive predictor of stroke, and high homocysteine (Hcy) is also associated with stroke. | 24039853 |
| Inflammation, Endothelial dysfunction | Altered Intercellular Communication | Our results demonstrate a novel role for c-Myc in the prevention of vascular pro-inflammatory phenotype, supporting an important physiological function as a central regulator of inflammation and endothelial dysfunction. | 24039874 |
| Inflammation, Colorectal Carcinoma | Altered Intercellular Communication | Collectively, the findings a) indicate that interleukin expression is influenced by ras signaling and specific interleukins play an oncogenic promoter role in colorectal cancer, highlighting the molecular link between inflammation and tumorigenesis, and b) accentuate the interwoven molecular correlations as leads to new therapeutic approaches in the future. | 24040001 |
| Waldenstrom Macroglobulinemia | Altered Intercellular Communication | Fifteen cases (4%) showed variable lymphoplasmacytic inflammation thus qualifying as IAA. | 24040436 |
| Periaortitis | Altered Intercellular Communication | Variable sclerosing lymphoplasmacytic inflammation was seen either confined to the adventitia (periaortitis; mainly in males) or extending through all layers (mainly in females). | 24040436 |
| Loss, Fibrosis Assessment, Interstitial inflammation | Altered Intercellular Communication | In human fibrotic kidneys, tubular epithelial cells (TECs) with intact tubular basement membrane (TBM) showed loss or down-regulation of an epithelial marker (E-cadherin), de novo expression of mesenchymal markers (vimentin and fibronectin), and significant up-regulation of inducers and mediators controlling the EMT process (transforming growth factor-b1 (TGF-b1), p-Smad2/3, b1-integrin, p38 mitogen-activated protein kinase (MAPK), WNT5B and b-catenin) in the areas of interstitial inflammation and fibrosis, compared with their expression in control kidneys. | 24040439 |
| Inflammation, Left coronary artery structure | Altered Intercellular Communication | Increased inflammation and Lm (mean linear intercept) scores were observed in chronic exposed mice, indicating emphysematous changes were present in lungs of chronic exposed mice. | 24040961 |
| Inflammation | Altered Intercellular Communication | P53 expression showed significant association with H. pylori (P = 0.005), invasion depth (P = 0.029) and inflammation reaction (P = 0.008). | 24042100 |
| Inflammation, Helicobacter pylori Positive | Altered Intercellular Communication | Biopsy sections from H. pylori-positive gastritis patients revealed more severe inflammation than those of H. pylori-negative patients. | 24042100 |
| ARCN1 gene, Inflammation, Staphylococcus aureus infection, doxorubicin/procarbazine/vincristine protocol, Acute inflammation | Altered Intercellular Communication | In this study, the levels and possible processing of MK in relation to S. aureus infection of the airways were investigated, comparing COPD and VAP, thus comparing a state of disease with preceding chronic inflammation and remodeling (COPD) with acute inflammation (that is, VAP). | 24043271 |
| ARCN1 gene, Inflammation | Altered Intercellular Communication | Taken together, proteases of both bacteria and the host contribute to degradation of the antibacterial protein MK, resulting in an impaired defense of the airways, in particular, in COPD where the state of chronic inflammation could be of importance. | 24043271 |
| Inflammation, Coronary Artery Disease | Altered Intercellular Communication | Inflammation may be an important driver of residual cardiovascular risk in patients with coronary artery disease despite aggressive statin therapy. | 24043299 |
| Inflammation | Altered Intercellular Communication | Chronic inflammation as a determinant of future aging phenotypes. | 24043651 |
| Inflammation | Altered Intercellular Communication | The importance of chronic inflammation as a determinant of aging phenotypes may have been underestimated in previous studies that used a single measurement of inflammatory markers. | 24043651 |
| Inflammation | Altered Intercellular Communication | We assessed inflammatory markers twice over a 5-year exposure period to examine the association between chronic inflammation and future aging phenotypes in a large population of men and women. | 24043651 |
| Inflammation | Altered Intercellular Communication | Chronic inflammation, as ascertained by repeat measurements, was associated with a range of unhealthy aging phenotypes and a decreased likelihood of successful aging. | 24043651 |
| Inflammation | Altered Intercellular Communication | Our results suggest that assessing long-term chronic inflammation by repeat measurement of interleukin-6 has the potential to guide clinical practice. | 24043651 |
| Inflammation, Carcinogenesis | Altered Intercellular Communication | Nitric oxide (NO) is a signaling molecule that plays an important role in inflammation and carcinogenesis. | 24044375 |
| vascular inflammations | Altered Intercellular Communication | We identified by non-targeted proteomic approach and confirmed by the means of independent techniques, the differential expression of several proteins indicating significantly increased vascular inflammation response, disturbance in the lipid metabolism and in atherogenic plaques stability. | 24044526 |
| Macrovesicular hepatic steatosis, Nephritis | Altered Intercellular Communication | In adult rats, the FRU diet induced transient elevations of MAP and HR in the 6th week, and, at 13 weeks, increased fasting glucose, triglycerides, total cholesterol, AST and ALT; increased liver, kidneys and retroperitoneal fat weights; and induced macrovesicular and microvesicular NAFLD, the presence of fat cells in the kidney, glomerular sclerosis, and liver and kidney inflammation. | 24044579 |
| Communicable Diseases, Inflammation, Pseudoepitheliomatous hyperplasia | Altered Intercellular Communication | Pseudocarcinomatous hyperplasia (PH) is a marked proliferation of benign squamous epithelium lacking cytologic atypia and pleomorphism in response to chronic stimuli, such as inflammation, infection, irradiation, or an underlying neoplastic reaction. | 24045190 |
| Inflammation, home health encounter | Altered Intercellular Communication | GI inflammation was common in HH patients, which from the different perspective, supports the notion that iron overload may lead to GI inflammation. | 24045277 |
| Inflammation, Periodontitis, Ischemic stroke | Altered Intercellular Communication | Biomarkers of periodontitis and inflammation in ischemic stroke: A case-control study. | 24045341 |
| Inflammation, Endotoxemia, Periodontal Infection, Destruction of tissue | Altered Intercellular Communication | We conclude that controls more often had evidence of current periodontal infection with higher periodontal pathogen amount, endotoxemia, local inflammation and tissue destruction. | 24045341 |
| Inflammation, Cerebrovascular accident | Altered Intercellular Communication | Additionally, inflammatory burden may contribute to high systemic inflammation associated with elevated stroke susceptibility. | 24045341 |
| Inflammation, Adult Non-Hodgkin Lymphoma, RTEL1 gene | Altered Intercellular Communication | Compromised immunity and chronic inflammation are thought to contribute to the development of non-Hodgkin lymphoma (NHL). | 24045922 |
| Inflammation, Colorectal Carcinoma | Altered Intercellular Communication | Genetic variation in the inflammation and innate immunity pathways and colorectal cancer risk. | 24045924 |
| Inflammation, Colorectal Carcinoma | Altered Intercellular Communication | It is widely accepted that chronic inflammation plays a role in the etiology of colorectal cancer. | 24045924 |
| Inflammation, Colorectal Carcinoma | Altered Intercellular Communication | Using a two-stage design, we examined the associations between colorectal cancer and common variation in 37 key genes in the inflammation and innate immunity pathways. | 24045924 |
| Gingivitis, Anemia, Sickle Cell | Altered Intercellular Communication | There was a statistically significant association between having mild, moderate or severe gingival inflammation and the severity of sickle cell anemia (P = 0.028). | 24046824 |
| Airway structure | Altered Intercellular Communication | Fractional exhaled nitric oxide (FeNO) is a non-invasive marker of airway inflammation. | 24046997 |
| Airway structure, Asthma, IL13 gene | Altered Intercellular Communication | As FeNO is a marker of lower airway inflammation, significantly higher FeNO levels in atopic allergic rhinitis patients suggest that it may be a predictor for onset of asthma in these patients. | 24046997 |
| Inflammation, Hypertensive (finding), Hypertension, CTCAE, Metabolic Syndrome X | Altered Intercellular Communication | Chemerin is strongly associated with markers of inflammation and components of the metabolic syndrome in hypertensive subjects and was independently associated with hypertension after adjustment for age, gender and metabolic risk factors. | 24047472 |
| Inflammation, Primary malignant neoplasm | Altered Intercellular Communication | Interleukin 6 (IL-6) signaling plays a role in inflammation, cancer, and senescence. | 24047696 |
| Inflammation, Malignant Pleural Mesothelioma, Pleural Tuberculosis, Empyema, Pleural Effusion, CTCAE, Secondary malignant neoplasm of pleura | Altered Intercellular Communication | The pathological diagnosis was as follows: pleural metastases in 899 (37.8%), primary pleural mesothelioma in 439 (18.4%), tuberculous pleurisy in 514 (21.6%), non-specific inflammation in 226 (9.5%), empyema in 190 (8.0%), hepatic pleural effusion in 36 (1.5%) and pleural effusion of unknown causes in 76 (3.2%) cases. | 24047806 |
| Pain Distress Question, Inflammation | Altered Intercellular Communication | The results suggest an effect of pain, which may be a possible marker of inflammation. | 24047870 |
| Giant Cell Arteritis, Inflammation, GCA gene, Autoimmune Disorder, CTCAE | Altered Intercellular Communication | Giant cell arteritis (GCA) is an autoimmune disorder characterized by the inflammation of medium to large vessels. | 24048107 |
| Inflammation | Altered Intercellular Communication | The lack of increased risk after one year suggests that an association based on shared risk factors or chronic inflammation is unlikely. | 24049127 |
| Inflammation, Calcium pyrophosphate deposition disease | Altered Intercellular Communication | All US findings indicative of peri-articular synovial inflammation were more frequently detected in patients with CPPD disease than in gouty patients. | 24050142 |
| Inflammation | Altered Intercellular Communication | In 50 out of 176 (28.4%) shoulders, US allowed the detection of at least one finding indicative of synovial inflammation. | 24050142 |
| Airway structure, Asthma | Altered Intercellular Communication | Preclinical studies suggest that interleukin-9 may be a central mediator in the development and maintenance of airway inflammation in asthma. | 24050312 |
| Inflammation, Heart failure | Altered Intercellular Communication | Oxidative stress and inflammation are hallmarks of the heart failure (HF) disease state. | 24050409 |
| Sepsis, Inflammation | Altered Intercellular Communication | Most importantly, levels of circulating U6 were significantly upregulated in sera of patients with critical illness and sepsis compared with controls and correlated with established markers of inflammation. | 24052167 |
| Inflammation, Fibrosis Assessment | Altered Intercellular Communication | Retroperitoneal fibrosis (RF) is a rare disease characterized by inflammation and fibrosis of retroperitoneal soft tissues. | 24052251 |
| Inflammation, Primary malignant neoplasm, Stomach Carcinoma | Altered Intercellular Communication | Chronic inflammation has been hypothesized to play a significant role in the aetiology of cancer, including gastric cancer. | 24052422 |
| Inflammation, Stomach Carcinoma | Altered Intercellular Communication | In the present study, we sought to examine pre-diagnostic systemic cytokine levels in plasma, which can be seen as markers of aggregate inflammation, and risk of distal gastric cancer in a case-control study nested within the prospective Shanghai Men's Health Study. | 24052422 |
| Stomach Carcinoma | Altered Intercellular Communication | Circulating levels of eight inflammation-related cytokines were measured in the plasma collected at baseline for 180 incident cases of distal gastric cancer and 358 matched controls. | 24052422 |
| Autoimmune Diseases, Inflammation, Lupus Erythematosus, Lupus Erythematosus, Systemic | Altered Intercellular Communication | Systemic lupus erythematosus (SLE) is an autoimmune-mediated disease, characterized by inflammation of small arteries and arterioles. | 24052468 |
| Inflammation, Complication Aspects | Altered Intercellular Communication | Inflammation is a key component in the pathogenesis of sulfur mustard (SM)-induced skin complications. | 24053005 |
| Prostate carcinoma | Altered Intercellular Communication | RHAMM overexpression may contribute to the development of hormonal resistance in prostate cancer. | 24053431 |
| Communicable Diseases, Inflammation, Large prostate | Altered Intercellular Communication | A history of prostate enlargement or inflammation was significantly associated with higher rates of both infectious (odds ratio [OR] = 3.7) and non-infectious (OR = 2.2) complications. | 24053621 |
| Steatohepatitis, Inflammation | Altered Intercellular Communication | Loss of estrogen receptor-alpha (ER-a) in the liver is associated with hepatic steatosis and inflammation in animal models. | 24054032 |
| Inflammation, Asthma | Altered Intercellular Communication | Elevation of S100 calcium binding protein A9 in sputum of neutrophilic inflammation in severe uncontrolled asthma. | 24054362 |
| Asthma | Altered Intercellular Communication | Neutrophilic airway inflammation is frequently observed in severe uncontrolled asthma (UA) and controlled asthma (CA). | 24054362 |
| Asthma | Altered Intercellular Communication | To identify biomarkers of severe uncontrolled asthma with neutrophilic airway inflammation. | 24054362 |
| Inflammation | Altered Intercellular Communication | S100A9 in sputum may be a biomarker of neutrophilic inflammation in severe UA. | 24054362 |
| Inflammation, Osage language | Altered Intercellular Communication | CPAP therapy could partially suppress systemic inflammation in OSA patients, and substantial differences were present among the various inflammatory markers. | 24054505 |
| Inflammation | Altered Intercellular Communication | Bioabsorbable polymers on drug-eluting stents may lower the long-term risks of inflammation, delayed healing, and adverse events. | 24055443 |
| Inflammation, Ischemia | Altered Intercellular Communication | Potential role of erythropoietin receptors and ligands in attenuating apoptosis and inflammation in critical limb ischemia. | 24055514 |
| Inflammation | Altered Intercellular Communication | The in vitro experiments demonstrate that ARA 290 decreases inflammation and apoptosis of ischemic myotubes. | 24055514 |
| Inflammation, Endothelium, Renal glomerular disease | Altered Intercellular Communication | Acute transplant glomerulopathy refers to alloimmune mediated endothelial injury and glomerular inflammation that typically occurs early post-kidney transplantation. | 24056179 |
| Autoimmune Diseases, Inflammation, vasculogenesis | Altered Intercellular Communication | Unlike TGF-b1(-/-) mice, the TGF-b1(Lb3/Lb3) mice show neither embryonic lethality nor signs of multifocal inflammation, demonstrating that knock-in of the TGF-b3 ligand can prevent the vasculogenesis defects and autoimmunity associated with TGF-b1 deficiency. | 24056369 |
| Inflammation, Weight decreased | Altered Intercellular Communication | Inflammation, functional status, and weight loss during recovery from cardiac surgery in older adults: a pilot study. | 24057224 |
| BDI - Functional Impairment, Weight decreased, Inflammation | Altered Intercellular Communication | The impacts of weight loss, functional impairment, and inflammation during recovery on disability and frailty warrant further study. | 24057224 |
| Inflammation, Apoptosis, Ischemic stroke, Cerebrovascular accident | Altered Intercellular Communication | The data of this work suggests that inflammation may have a role in platelet apoptosis in stroke which may suggest a new aspect of the role of inflammation in the development of acute ischemic stroke. | 24057255 |
| Inflammation | Altered Intercellular Communication | Neutrophil-lymphocyte ratio, an emerging marker of inflammation, was independently associated with the presence of LA thrombus in patients with nonvalvular AF. | 24057399 |
| Sample Size Calculation, Fibrosis Assessment, Inflammation, AUTOIMMUNE DISEASE, MULTISYSTEM, INFANTILE-ONSET, 1 | Altered Intercellular Communication | Systemic sclerosis (SSc) is a multisystem autoimmune disease of unknown etiology characterized by inflammation, autoantibody production, and fibrosis. | 24058548 |
| Inflammation, Endotoxemia, Diabetes Mellitus, Non-Insulin-Dependent | Altered Intercellular Communication | Inulin controls inflammation and metabolic endotoxemia in women with type 2 diabetes mellitus: a randomized-controlled clinical trial. | 24059649 |
| Inflammation, Endotoxemia, Diabetes Mellitus, Non-Insulin-Dependent | Altered Intercellular Communication | It can be concluded that inulin supplementation seems to be able to modulate inflammation and metabolic endotoxemia in women with type 2 diabetes. | 24059649 |
| Inflammation, Kidney Failure, Injury of kidney | Altered Intercellular Communication | We analyzed two common genetic polymorphisms that have previously been linked to renal failure and inflammation, and have been supposed to be associated with cardiac surgery associated-acute kidney injury (CSA-AKI). | 24059882 |
| Kidney Failure, Chronic, Inflammation, Failure (biologic function) | Altered Intercellular Communication | [The effects of failure of low density lipoprotein receptor expression induced by inflammation on radial artery foam cell formation in patients with end-stage renal disease]. | 24059991 |
| Kidney Failure, Chronic, Inflammation | Altered Intercellular Communication | To investigate whether inflammation exacerbates lipid accumulation in the radial arteries of patients with end-stage renal disease (ESRD) and to explore its underlying mechanisms. | 24059991 |
| Inflammation | Altered Intercellular Communication | Confocal microscopy observation showed that inflammation enhanced the translocation of SCAP escorting SREBP-2 from endoplasmic reticulum to Golgi, thereby activating LDLr gene transcription. | 24059991 |
| Inflammation | Altered Intercellular Communication | Further analysis showed that dysregulation of LDLr pathway induced by inflammation was associated with increased protein expression of mTOR (r = 0.733, P < 0.05), especially with the enhanced co-expression of mTOR and SREBP-2(P < 0.05). | 24059991 |
| Kidney Failure, Chronic | Altered Intercellular Communication | Inflammation accelerates the progression of foam cell formation in ESRD patients via dysregulation of LDLr pathway, which might be partly through the activation of mTOR pathway. | 24059991 |
| Sjogrens Syndrome", Inflammation | Altered Intercellular Communication | Reciprocal relation between GADD153 and Del-1 in regulation of salivary gland inflammation in Sjogren syndrome. | 24060278 |
| Sjogrens Syndrome", Inflammation, GYPB gene | Altered Intercellular Communication | Accordingly, we tested the hypothesis that Sjogren's syndrome (SS) is associated with increased salivary gland expression of GADD153 and increased leukocyte infiltration in association with decreased Del-1 thereby contributing to inflammation and cell death. | 24060278 |
| Inflammation, Cell Death | Altered Intercellular Communication | Our collective observations suggested that GADD153 directly and/or indirectly through downregulation of Del-1 contributes importantly to salivary gland inflammation and cell death. | 24060278 |
| Inflammation | Altered Intercellular Communication | Collectively, the results indicate that GADD153 regulates inflammation and cell death in salivary gland in SS. | 24060278 |
| Sialadenitis | Altered Intercellular Communication | Further, Del-1 expression likely provides a mechanistic link between increased GADD153 and leukocyte infiltration and accompanying inflammation of salivary gland tissue in this condition. | 24060278 |
| Inflammation | Altered Intercellular Communication | Splenectomy was associated with reversals of increased pHb, RBC adhesion, reticulocytes, RBC marker expression and inflammation in HS. | 24060729 |
| Inflammation | Altered Intercellular Communication | In contrast to the normal tunica consisting of a thin fibrous wall lined by a monolayer of flattened bland mesothelium and no significant inflammation, all of our cases were characterized by background changes of fibroblastic organization and stromal chronic inflammation. | 24061516 |
| Vascular Diseases, Hemorrhage, Interstitial inflammation, Infarction, Tubular atrophy | Altered Intercellular Communication | One case showed only segmental tubular atrophy with interstitial inflammation and vasculopathy; no infarct or hemorrhage was identified. | 24061519 |
| Interstitial inflammation | Altered Intercellular Communication | Interstitial inflammation was seen adjacent to damaged testicular parenchyma in all 30 cases. | 24061519 |
| Vasculitis, CTCAE, Interstitial inflammation, Avascular Necrosis, CTCAE | Altered Intercellular Communication | All clinical acute torsion cases showed both parenchymal and fibrinoid vascular necrosis, and 10 had hemorrhage/hematoma; they lacked vasculitis, interstitial inflammation, and chronic vascular changes. | 24061519 |
| Inflammation, Heart failure, Bipolar Disorder | Altered Intercellular Communication | Inflammation may be a link between depressive symptoms and outcomes in patients with heart failure. | 24062026 |
| Inflammation, Heart failure, Bipolar Disorder | Altered Intercellular Communication | Our findings, in combination with prior researchers', suggest there is not a robust relationship between depressive symptoms and individual biomarkers of inflammation in heart failure. | 24062026 |
| Inflammation, Systemic Inflammatory Response Syndrome, Toxic effect | Altered Intercellular Communication | Patients with severe DFI, as by manifesting two or more signs of systemic inflammation or toxicity, had higher rates of major amputation and longer hospital stays and required more surgery and more subsequent admissions than patients who did not manifest SIRS. | 24062324 |
| Inflammation, Obesity | Altered Intercellular Communication | Chronic inflammation exists in population of PDC and obesity people. | 24063213 |
| Inflammation | Altered Intercellular Communication | Strict control of inflammation may result in closure of the macular hole and avoid the need for vitrectomy. | 24063599 |
| Inflammation, Behcet Syndrome | Altered Intercellular Communication | To evaluate the long-term efficacy and safety of intravitreal triamcinolone acetonide (IVTA) injection for posterior segment inflammation in Behcet disease (BD) patients. | 24063666 |
| Inflammation, Chronic Obstructive Airway Disease | Altered Intercellular Communication | Chronic obstructive pulmonary disease is known to be associated with systemic inflammation. | 24064740 |
| Inflammation, Respiratory physiology | Altered Intercellular Communication | In the present study, we found longitudinal observational evidence that suggested that increases in systemic inflammation are associated with declines in lung function. | 24064740 |
| Inflammation, Overweight, Osteoarthritis, Knee | Altered Intercellular Communication | Effects of intensive diet and exercise on knee joint loads, inflammation, and clinical outcomes among overweight and obese adults with knee osteoarthritis: the IDEA randomized clinical trial. | 24065013 |
| TNF protein, human, Inflammation, Heart failure | Altered Intercellular Communication | TNF-a, a marker of inflammation, was significantly increased in heart failure (p = 0.004) but there was no difference between HF-D and HF-I groups; however, Galectin-3 was significantly increased in the HF-D group compared to the HF-I group (p = 0.005). | 24065222 |
| Inflammation, Carpal Tunnel Syndrome, Carotid Intima-Media Thickness | Altered Intercellular Communication | Chronic inflammation beyond the traditional cardiovascular risk factors might be related to increased carotid intima-media thickness in patients with carpal tunnel syndrome. | 24065256 |
| Inflammation, Chronic heart failure, square decimeter, Smoking | Altered Intercellular Communication | Smoking, chronic heart failure, and subclinical inflammation may be associated with high platelet reactivity in patients with DM2 treated with ASA. | 24065375 |
| Anemia | Altered Intercellular Communication | Inflammation markers were elevated (leukocytosis 22 100/ml, CRP 22 mg/dl ), there was mild anemia (hemoglobin 9.7 mg/dl) and digitoxin blood level was increased to 56 mg/l (therapeutic range 10-30 mg/l). | 24065415 |
| Pain Distress Question, Rheumatoid Arthritis, Inflammation | Altered Intercellular Communication | Folklore remedies for pain and inflammation in rheumatoid arthritis include the application of magnets and copper to the skin. | 24066023 |
| Fibrosis Assessment, Pneumoconiosis, Pneumonitis | Altered Intercellular Communication | Coal workers' pneumoconiosis (CWP) is characterized by chronic pulmonary inflammation and fibrotic nodular lesions that usually lead to progressive fibrosis. | 24066042 |
| Inflammation | Altered Intercellular Communication | Inflammation is the first step in the development of CWP. | 24066042 |
| Inflammation, transplantation aspects | Altered Intercellular Communication | Post-transplantation encapsulating peritoneal sclerosis without inflammation or radiological abnormalities. | 24067112 |
| Inflammation, Elastosis perforans serpiginosa | Altered Intercellular Communication | Systemic inflammation and abnormalities on an abdominal computed tomography (CT) scan are important hallmarks of EPS. | 24067112 |
| Inflammation, Elastosis perforans serpiginosa | Altered Intercellular Communication | To our knowledge, this is the first report of a case being diagnosed with late-onset post-transplantation EPS without systemic inflammation or abnormalities on a CT scan which could only be diagnosed by laparotomy. | 24067112 |
| Inflammation, Elastosis perforans serpiginosa | Altered Intercellular Communication | EPS may occur several years after kidney transplantation in the absence of inflammation and typical radiological abnormalities. | 24067112 |
| Neoplastic, Inflammation | Altered Intercellular Communication | Both angiogenesis and lymphogenesis vessels were more numerous in the areas where the inflammatory infiltrate was more abundant, which suggests that chronic inflammation plays the part of a promoter factor of neoplastic lesions. | 24068414 |
| Inflammation, Gout | Altered Intercellular Communication | Oxidized low density lipoprotein and inflammation in gout patients. | 24068523 |
| Inflammation, Gout | Altered Intercellular Communication | The changes in ox-LDL levels may be associated with enhanced inflammation in gout patients. | 24068523 |
| Communicable Diseases, Inflammation | Altered Intercellular Communication | Interestingly, although the bacteria could be found in consecutive samples taken at different points in time, there were no signs of advancing infection or inflammation. | 24068980 |
| Inflammation, Carcinogenesis, Neoplasms | Altered Intercellular Communication | Intercellular adhesion molecule (ICAM)-1, a cell adhesion molecule with a key role in inflammation and immunosurveillance, was implicated in carcinogenesis by facilitating instability in the tumor environment. | 24069166 |
| Lymphadenitis, Tuberculosis | Altered Intercellular Communication | Nasal tuberculosis is a specific inflammatory process which is, in most cases, joined by the inflammation of neck lymph nodes. | 24069829 |
| Autoimmune Diseases, Sample Size Calculation, Fibrosis Assessment, vascular inflammations | Altered Intercellular Communication | An abnormal generation of reactive oxygen species (ROS) is thought to contribute to systemic sclerosis (SSc), fostering autoimmunity, fibrosis, and vascular inflammation. | 24070090 |
| Vasculitis, Sample Size Calculation | Altered Intercellular Communication | Here we investigate whether oxidative stress regulates the cross-talk between leukocytes and platelets via HMGB1, thus contributing to vessel inflammation in SSc. | 24070090 |
| Inflammation, Osteopenia | Altered Intercellular Communication | Between-group differences were greater in patients with higher periodontal inflammation at baseline (mean -0.74 [95% CI: -1.29 to -0.19], p = 0.01) and in patients with severe bone loss at baseline (-0.61 [95% CI: -1.16 to -0.054], p = 0.03). | 24070911 |
| Inflammation | Altered Intercellular Communication | Furthermore, the changes in periodontal inflammation correlated with changes in carotid inflammation (R = 0.61, p < 0.001). | 24070911 |
| Inflammation, Periodontitis, Atherosclerosis | Altered Intercellular Communication | Given the concomitant changes observed in periodontal and arterial inflammation, these data raise the possibility that a portion of that beneficial impact of statins on atherosclerosis relate to reductions in extra-arterial inflammation, for example, periodontitis. | 24070911 |
| Inflammation, Primary malignant neoplasm | Altered Intercellular Communication | reduced caloric intake, inflammation and greater fat metabolism) may be present in older patients with cancer, along with poorer levels of functional capacity, compared to healthy controls. | 24071543 |
| Inflammation, Adverse reaction to drug, Pneumonia, Alveolar damage, Pulmonary cryptococcosis, Pneumonia, Interstitial | Altered Intercellular Communication | The increase in surface area and quality of biopsy samples translated to a high percentage of alveolated tissue (70 %) that enabled a clear histological detection of the following diagnoses: noncaseating granulomatous inflammation (n = 2), acute interstitial pneumonitis consistent with drug reaction (n = 5), nonspecific interstitial pneumonia fibrotic variant (n = 1), diffuse alveolar damage (n = 3), organizing pneumonia (n = 3), and pulmonary cryptococcal pneumonia (n = 1). | 24071930 |
| Sepsis, Inflammation | Altered Intercellular Communication | Further research is needed to determine how excess adiposity modulates inflammation from sepsis. | 24072354 |
| Malignant neoplasm of urinary bladder, Inflammation, Fibrosis Assessment, Neoplasms | Altered Intercellular Communication | To investigate the efficacy of diffusion-weighted MRI (DWI) in differentiating recurrent tumor from chronic inflammation and fibrosis after cystectomy or transurethral resection of bladder cancer. | 24072383 |
| Fibrosis Assessment, Acute inflammation, Neoplasms | Altered Intercellular Communication | The normalized apparent diffusion coefficients of recurrent tumors (0.697 +- 0.219) were significantly (P < 0.05) lower than those of postoperative inflammation or fibrosis (1.019 +- 0.143). | 24072383 |
| Bladder Neoplasm, Fibrosis Assessment, Acute inflammation | Altered Intercellular Communication | DWI is superior to DCE MRI for differentiating recurrent bladder tumors from postoperative inflammation or fibrosis. | 24072383 |
| Hyperplasia of pituitary gland, Hyperprolactinemia, Primary Hypothyroidism | Altered Intercellular Communication | Brain imaging findings showed pituitary hyperplasia; hormonal assessment revealed primary hypothyroidism and hyperprolactinemia. | 24072579 |
| Inflammation, Coronary Artery Disease | Altered Intercellular Communication | Interleukin-6 (IL-6) a pleiotropic cytokine is a central mediator of inflammation in the pathogenesis of coronary artery disease (CAD). | 24072607 |
| Inflammation, Anemia | Altered Intercellular Communication | Anemia related to inflammation dominated the different types of anemia. | 24073709 |
| Inflammation | Altered Intercellular Communication | A low-grade inflammation has been reported to occur in PI-IBS. | 24073715 |
| Constipation, Inflammation, Ichthyosis Bullosa of Siemens, Gastroenteritis | Altered Intercellular Communication | A 20-year-old female with a diagnosis of IBS with constipation (IBS-C), according to Rome III criteria, contracted Campylobacter-induced gastroenteritis, after which her symptom pattern changed to IBS-M. She showed an intestinal low-grade inflammation that was manifested by an increase in the number of intraepithelial and lamina propria leucocytes and lymphocytes and an increase in the density of mast cells in lamina propria. | 24073715 |
| Inflammation, Gastroenteritis, Post-infectious disorder | Altered Intercellular Communication | Gastroenteritis in patients with IBS-C causes a post-infectious, low-grade inflammation. | 24073715 |
| Data types - Address, Dermatitis | Altered Intercellular Communication | Collectively, our findings argue for early intervention strategies designed to mitigate skin inflammation in children with AD. | 24074334 |
| Keratoconjunctivitis, Vernal, Inflammation | Altered Intercellular Communication | Vernal keratoconjunctivitis (VKC) is a bilateral chronic, seasonally exacerbated inflammation of the ocular surface that especially affects male children and young boys. | 24074451 |
| Inflammation, Herpes zoster disease, Neuralgia | Altered Intercellular Communication | Deficiencies of these nutrients may induce dysregulated inflammation and oxidative damage leading to neuropathic pain in patients with herpes zoster. | 24074834 |
| Inflammation, SELENON gene, Cardiomyopathies | Altered Intercellular Communication | We present an original case of a 32-year-old woman with RSS with dilated a cardiomyopathy who on cardiac biopsy showed occasional hypertrophic and atrophic myocytes with no evidence of inflammation, abnormal sarcomeres and disintegration of the Z bands on ultrastructural analysis, abnormal desmin, and normal C9 immunoreactivity. | 24075556 |
| Autoimmune Diseases, Atherosclerosis | Altered Intercellular Communication | Cytotoxic CD4(+)CD28(null) cells are generated under inflammatory conditions and implicated in a variety of pathological processes like atherosclerosis and autoimmune diseases. | 24075776 |
| Inflammation | Altered Intercellular Communication | There is a low level of correlation between clinical and endoscopic and histologic subscores of patients with IPAA; clinical symptoms therefore might not reflect objective evidence of inflammation. | 24075890 |
| Inflammation | Altered Intercellular Communication | These findings, along with evidence of correlation between total scores and clinical symptoms, indicate that these indices do not accurately identify patients with pouch inflammation. | 24075890 |
| Inflammation | Altered Intercellular Communication | Further research is required to understand additional factors that contribute to clinical symptoms in the absence of objective signs of pouch inflammation. | 24075890 |
| Clinical Events Domain | Altered Intercellular Communication | CE was better than SBFT and equivalent to ileocolonoscopy in detecting small-bowel inflammation. | 24075891 |
| Inflammation, Diabetes Mellitus, Non-Insulin-Dependent, Diabetes Mellitus | Altered Intercellular Communication | Chronic low-grade systemic inflammation presented in Type 2 diabetes mellitus plays a major role in disease progression as well as development of micro- and macro-vascular complications of diabetes. | 24076594 |
| Inflammation, Complications of Diabetes Mellitus | Altered Intercellular Communication | Therefore, reducing inflammation can be beneficial in prevention of diabetes complications. | 24076594 |
| Inflammation, diabetic | Altered Intercellular Communication | Inflammation was associated with insulin resistance in diabetic patients. | 24076594 |
| Thrombotic Microangiopathies, Inflammation, Endocardium, Blood Clot | Altered Intercellular Communication | One of the proposed mechanisms of origin of these masses is organizing thrombi in the setting of endocardial injury and inflammation questioning a possible link to thrombotic microangiopathy. | 24077148 |
| Inflammation, "Alzheimers Disease", Data types - Address | Altered Intercellular Communication | Oxidative stress, inflammation, and increased cholesterol levels are all mechanisms that have been associated with Alzheimer's disease (AD) pathology. | 24077434 |
| Inflammation, Chronic Kidney Diseases | Altered Intercellular Communication | Carotid intima media thickness, oxidative stress, and inflammation in children with chronic kidney disease. | 24077647 |
| Inflammation, Chronic Kidney Diseases | Altered Intercellular Communication | We evaluated the association between inflammation and oxidative stress with carotid intima media thickness (cIMT) and elasticity increment module (E(inc)) in pediatric patients with chronic kidney disease (CKD). | 24077647 |
| Inflammation | Altered Intercellular Communication | MMP-1 overexpression induced by IL-1b: possible mechanism for inflammation in degenerative lumbar facet joint. | 24077757 |
| Degeneration of lumbar intervertebral disc, Inflammation, Radiculopathy, Abnormal degeneration | Altered Intercellular Communication | More and more attention has been focused on the inflammation or degeneration caused by biochemical factors in radiculopathy during lumbar facet joint degeneration. | 24077757 |
| Inflammation, Laryngeal Nerve Paralysis | Altered Intercellular Communication | The mechanisms of vocal cord fixation can be classified into mechanical articular fixation, direct injury of the recurrent laryngeal nerve, or recurrent laryngeal nerve paralysis secondary to inflammation. | 24077868 |
| vascular inflammations, Thrombosis, Choline Dehydrogenase, Mitochondrial | Altered Intercellular Communication | Different cell-derived MPs in CHD may indicate the different pathophysiological changes in vessels, and MPs may both participate in the development of thrombosis and enhance the vascular inflammation. | 24078095 |
| Inflammation, Pain Distress Question | Altered Intercellular Communication | In three cases, a sterile inflammation adjacent to the geneX(r) occurred, with delayed wound healing in two patients and local pain. | 24078171 |
| Inflammation, Pain Distress Question | Altered Intercellular Communication | We concluded from this series of patients that geneX(r) causes soft tissue inflammation and pain with its use. | 24078171 |
| ARCN1 gene, Inflammation | Altered Intercellular Communication | In conclusion, NLR could be considered as a new inflammatory marker for assessment of inflammation in COPD patients with its quick, cheap, easily measurable property with routine complete blood count analysis. | 24078279 |
| Vasculitis, Inflammation, Vasculitis, CTCAE | Altered Intercellular Communication | Ab-related angiitis: comparison with CAA without inflammation and primary CNS vasculitis. | 24078731 |
| Cerebral Amyloid Angiopathy, Inflammation, Vasculitis, Granulomatous Angiitis | Altered Intercellular Communication | Specimens reviewed by a neuropathologist showed 40 with vascular Ab peptide without inflammation (cerebral amyloid angiopathy [CAA]), 28 with granulomatous vasculitis (Ab-related angiitis or ABRA), and 10 with perivascular CAA-related inflammation. | 24078731 |
| ARCN1 gene, Inflammation | Altered Intercellular Communication | Increased serum ox-LDL levels correlated with lung function, inflammation, and oxidative stress in COPD. | 24078777 |
| ARCN1 gene, Abnormal inflammatory response, Chronic Obstructive Airway Disease | Altered Intercellular Communication | Chronic obstructive pulmonary disease (COPD) is associated with abnormal inflammation and high oxidative stress. | 24078777 |
| ARCN1 gene, Inflammation | Altered Intercellular Communication | This study compared serum levels of ox-LDL in 48 COPD patients and 32 health controls and correlated them with lung function, systematic inflammation, and oxidative stress. | 24078777 |
| ARCN1 gene, Inflammation | Altered Intercellular Communication | These results suggest that serum levels of ox-LDL are increased in COPD patients and that these levels are associated with lung function, inflammation, and oxidative stress in COPD. | 24078777 |
| Inflammation, Weight decreased | Altered Intercellular Communication | These results demonstrate that on a moderate carbohydrate background diet, accompanied by weight loss, the inclusion of whole eggs improves inflammation to a greater extent than yolk-free egg substitute in those with MetS. | 24079288 |
| Corneal epithelial defect, Inflammation, Infiltrate of cornea, Conjunctival hyperemia | Altered Intercellular Communication | In the development stage, marked conjunctival hyperaemia, a corneal epithelial defect, obvious corneal infiltration and progressive inflammation were seen; pathological changes comprised abundant inflammatory cells and a rounded cyst in the oedematous stroma, as well as a very small amount of neovascularization. | 24079482 |
| Inflammation, Stomach Carcinoma, Atrophic | Altered Intercellular Communication | Compared to a nongastric cancer group that was matched according to gender and age, the incidence of endoscopic atrophy (3.52 +- 1.45 vs. 4.85 +- 1.18, p < 0.001), histological atrophy at the greater curvature of the antrum (1.42 +- 0.80 vs. 1.95 +- 0.86, p = 0.0059), inflammation (2.05 +- 0.59 vs. 2.33 +- 0.66, p = 0.031), IM at the greater curvature of the corpus (0.06 +- 0.30 vs. 0.24 +- 0.54, p = 0.029), the ratio of OLGA-stage 0-II/III, IV (13/8 vs. 55/11, p = 0.038) were significantly higher for the gastric cancer group. | 24079881 |
| Inflammation, Stomach Carcinoma, Atrophic | Altered Intercellular Communication | Severe endoscopical atrophy, OLGA staging, histological atrophy at the antrum, inflammation, and particularly IM at the corpus, were identified as risk factors for gastric cancer development following H. pylori eradication. | 24079881 |
| Inflammation, Spondylitis | Altered Intercellular Communication | Macrophage phenotype in the subclinical gut inflammation of patients with ankylosing spondylitis. | 24080254 |
| Inflammation, Crohn Disease | Altered Intercellular Communication | Long-term evolution of subclinical gut inflammation to overt Crohn's disease (CD) has been described in AS patients. | 24080254 |
| Inflammation | Altered Intercellular Communication | The absence of CD14(+) macrophages together with the expansion of resolution phase and M2 macrophages is the immunological signature of subclinical ileal inflammation in AS. | 24080254 |
| Inflammation, Pain Distress Question | Altered Intercellular Communication | Targeting systemic inflammation in patients with obesity-related pain: Obesity- related pain: time for a new approach that targets systemic inflammation. | 24080568 |
| Pain Distress Question, Inflammation, Obesity, Disability, Weight decreased | Altered Intercellular Communication | We may be able to reduce pain, disability, and related comorbidities in obese patients by implementing modest weight loss and fitness interventions to address systemic inflammation. | 24080568 |
| Gallbladder Carcinoma | Altered Intercellular Communication | Evaluation of two inflammation-based prognostic scores in patients with resectable gallbladder carcinoma. | 24081806 |
| Primary malignant neoplasm | Altered Intercellular Communication | A number of inflammation-based prognostic scores have been established to help predict survival after surgery for several types of cancer. | 24081806 |
| Tissue Dissection, Inflammation | Altered Intercellular Communication | Consequently, during pedicle dissection, significant inflammation was found in the vicinity of the right portal vein. | 24081808 |
| Chronic lymphocytic inflammation, Pontine structure | Altered Intercellular Communication | CLIPPERS syndrome (chronic lymphocytic inflammation with pontine perivascular enhancement responsive to steroids) is an inflammatory process of the central nervous system whose distinguishing features are the enhancing punctiform lesions in the brainstem that appear in the magnetic resonance images. | 24081890 |
| Sleep-Disordered Breathing, Primary malignant neoplasm, Inflammation | Altered Intercellular Communication | Sleep disordered breathing (SDB) has been associated with oxidative stress, inflammation, and altered hormonal levels, all of which could affect the risk of cancer. | 24082302 |
| Sleep-Disordered Breathing, Primary malignant neoplasm, Inflammation | Altered Intercellular Communication | Sleep disordered breathing (SDB) has been associated with oxidative stress, inflammation, and altered hormonal levels, all of which could affect the risk of cancer. | 24082302 |
| Inflammation | Altered Intercellular Communication | These results provide additional evidence that inflammation is a factor in the mechanisms that cause incident mobility disability and suggest that a combined measure of inflammatory markers may improve prediction of functional prognosis. | 24083386 |
| methyldopa, Inflammation | Altered Intercellular Communication | Our data support the central role of inflammation in the pathogenesis of AMD and provide further evidence of a systemic involvement in AMD etiology. | 24083687 |
| Inflammation, Carcinoma of lung | Altered Intercellular Communication | In addition, smoking would be an important contributor to the processes of inflammation and lung cancer. | 24083740 |
| Inflammation | Altered Intercellular Communication | These results suggest that Yusho patients have dysregulated TH17 cell-mediated immune responses that may be linked to inflammation. | 24083809 |
| Inflammation, Heart failure, Endothelial dysfunction | Altered Intercellular Communication | Body mass index in chronic heart failure: association with biomarkers of neurohormonal activation, inflammation and endothelial dysfunction. | 24083942 |
| Arterial Stiffness, Inflammation, Hypertensive heart disease | Altered Intercellular Communication | Markers of inflammation and arterial stiffness were lowest in the normotensive group and highest in patients with hypertensive heart disease; endothelial markers were similar between groups. | 24084214 |
| Arterial Stiffness, Inflammation | Altered Intercellular Communication | In conclusion, markers of inflammation and arterial stiffness are independently related to BP. | 24084214 |
| Inflammation, Primary malignant neoplasm, Neoplasm Metastasis | Altered Intercellular Communication | The concept of the involvement of systemic inflammation in cancer progression and metastases has gained attraction within the past decade. | 24084772 |
| Pneumonitis | Altered Intercellular Communication | Global lung parenchymal glycolysis and lung parenchymal SUVmean may serve as potentially useful biomarkers to quantify lung inflammation on FDG PET/CT following thoracic radiation therapy. | 24085504 |
| Inflammation | Altered Intercellular Communication | Pre-diabetes is characterized by increased cardiovascular risk and chronic inflammation. | 24085683 |
| Inflammation, Cardiovascular Diseases | Altered Intercellular Communication | Perceived stress and coping strategies may influence the risk of cardiovascular disease through their possible association with inflammation, but data remain controversial for perceived stress or scanty for coping strategies. | 24085705 |
| HIV Antigens, Atherosclerosis | Altered Intercellular Communication | Monocytes play a pivotal role in atherosclerosis, and may be major mediators of HIV-associated inflammation. | 24086545 |
| Inflammation, HIV Infections, Cardiovascular Diseases | Altered Intercellular Communication | Hyper-inflammatory IL-1b enriched monocytes may be a major source of IL-6 production and systemic inflammation in HIV-infected adults, and may contribute to the risk for all-cause mortality and cardiovascular disease in treated HIV infection. | 24086545 |
| Inflammation, Muscle degeneration | Altered Intercellular Communication | Transgenic FHL1 expression increased sarcolemmal membrane stability, reduced muscle degeneration, decreased inflammation and conferred protection from contraction-induced injury in mdx mice. | 24087791 |
| Airway structure, ARCN1 gene | Altered Intercellular Communication | Respiratory viral detection and small airway inflammation in lung tissue of patients with stable, mild COPD. | 24088037 |
| Airway structure | Altered Intercellular Communication | The two groups were compared for viral prevalence and load, and airway inflammation. | 24088037 |
| ARCN1 gene, influenza A virus | Altered Intercellular Communication | Lung tissue of COPD patients had a significantly higher prevalence of viral nucleic acid (particularly influenza A virus), and increased inflammation of small airways by macrophages and neutrophils versus controls. | 24088037 |
| ARCN1 gene, Inflammation | Altered Intercellular Communication | The lung tissue of patients with stable, mild COPD has a higher prevalence and load of respiratory viruses versus non-obstructed control subjects, and increased inflammation of small airways. | 24088037 |
| ARCN1 gene, Airway structure | Altered Intercellular Communication | Cigarette smoking is the major risk factor for COPD, leading to chronic airway inflammation. | 24088173 |
| ARCN1 gene, Pneumonitis | Altered Intercellular Communication | We hypothesized that cigarette smoke induces structural and functional changes of airway epithelial mitochondria, with important implications for lung inflammation and COPD pathogenesis. | 24088173 |
| Inflammation, Cardiac dysfunction | Altered Intercellular Communication | Influence of cardiac dysfunction and systemic inflammation on pulmonary function and airway responsiveness in obese subjects. | 24088331 |
| Inflammation, Dyslipidemias, Dysglycemia | Altered Intercellular Communication | Altered cardiac function, dysglycemia and dyslipidemia do not seem to be significantly associated with AHR in severely obese subjects in contrast to systemic inflammation. | 24088331 |
| vascular inflammations | Altered Intercellular Communication | Lipoprotein-associated phospholipase A2 (Lp-PLA2) is a specific biomarker specific for vascular inflammation. | 24089018 |
| Inflammation, Dental Plaque | Altered Intercellular Communication | Inflammation has a significant association with plaque progression. | 24089018 |
| HD Term Type, Inflammation, Cachexia, Overhydration | Altered Intercellular Communication | Protein-energy wasting (PEW), associated with inflammation and overhydration, is common in haemodialysis (HD) patients and is associated with high morbidity and mortality. | 24089158 |
| HD Term Type, Inflammation | Altered Intercellular Communication | Assess the relationship between nutritional status, markers of inflammation and body composition through bioimpedance spectroscopy (BIS) in HD patients. | 24089158 |
| glycation | Altered Intercellular Communication | The receptor for advanced glycation end products (RAGE) is an inflammation-perpetuating receptor, and soluble RAGE (sRAGE) is a marker of cellular RAGE expression. | 24089588 |
| Inflammation, Malignant Neoplasms | Altered Intercellular Communication | Recent studies have shown that the presence of systemic inflammation correlates with poor survival in various of cancers. | 24089602 |
| Inflammation, Plaque, Atherosclerotic | Altered Intercellular Communication | The latter can be considered as target for suppression of inflammation and achievement of stabilization of atherosclerotic plaque. | 24090379 |
| Inflammation | Altered Intercellular Communication | She also had myodesospsia, syphilids and syphilitic roseola, together with laboratory indicators of inflammation. | 24090892 |
| Inflammation, Hernia | Altered Intercellular Communication | The hernia sac can be used to repair the inguinal hernia because it's a patient's tissue with no inflammation and rejection. | 24091173 |
| ARCN1 gene, Inflammation | Altered Intercellular Communication | COPD is also characterized by low-grade systemic inflammation. | 24091482 |
| ARCN1 gene, Inflammation | Altered Intercellular Communication | However, the relationship between physical activity and systemic inflammation in COPD is unclear. | 24091482 |
| ARCN1 gene, Inflammation | Altered Intercellular Communication | These results provide the conceptual basis to study whether an intervention to promote walking will reduce systemic inflammation in people with COPD. | 24091482 |
| Inflammation, Mediastinitis | Altered Intercellular Communication | A two-staged strategy to treat postoperative mediastinitis was scheduled, i.e., the setting up of a vacuum-assisted closure system until the improvement of inflammation followed by wound closure with pedicled omental grafting. | 24091537 |
| Necrosis with inflammation | Altered Intercellular Communication | Inflammasome components and necro-inflammation were evaluated in acinar cells by immunofluorescence (IF), histology, and biochemical approaches. | 24091659 |
| Airway structure, ARCN1 gene | Altered Intercellular Communication | Airway inflammation, including excess nitric oxide generation in the peripheral airways, might be related to the pathophysiology of COPD. | 24091810 |
| Granulomatous inflammation, Sarcoidosis, Pulmonary Fibrosis | Altered Intercellular Communication | This may be useful in identifying exhaled biomarkers of granulomatous inflammation and pulmonary fibrosis in patients with sarcoidosis. | 24091835 |
| Granulomatous inflammation, Sarcoidosis | Altered Intercellular Communication | EBC markers of granulomatous inflammation are detectable at greater levels in patients with sarcoidosis compared to healthy controls subjects. | 24091835 |
| Inflammation, Neoplasm Metastasis | Altered Intercellular Communication | Our data demonstrate a previously unknown multi-targeted involvement of TNF-a in PDA lipogenesis and inflammation and metastasis and suggest that intratumoral introduction of TNF-a may have the potential as a novel therapeutic approach in human PDA. | 24091913 |
| Inflammation, Infection, Cerebrovascular accident | Altered Intercellular Communication | There is good evidence that respiratory and other infections that cause systemic inflammation can trigger strokes; however, the role of specific infections is unclear. | 24092802 |
| Joint laxity, CLEFT LIP/PALATE WITH ABNORMAL THUMBS AND MICROCEPHALY, Microspectrophotometry, Chronic musculoskeletal pain, Pain | Altered Intercellular Communication | Chronic musculoskeletal pain (MSP) is common in children and can be due to several non-inflammatory conditions such as the benign joint hypermobility syndrome (BJHS), and growing pains (GP). | 24093536 |
| Inflammation | Altered Intercellular Communication | There were cases of inflammation seen in axial images of a 3D T1-weighed gradient echo sequence not reflected in the perfusion data. | 24093565 |
| Inflammation, Malignant Neoplasms | Altered Intercellular Communication | Colliquation found on the ultrasound images led to a biopsy, the result of which indicated only an inflammation, without any malignancy. | 24093821 |
| Granulomatous inflammation | Altered Intercellular Communication | This excluded the presence of a foreign body but showed that the left main bronchus was partially obstructed with caseous material and showed significant signs of granulomatous inflammation on the wall. | 24094042 |
| Inflammation, Metabolic Syndrome X, ETV3 wt Allele, Diabetes Mellitus, Coronary heart disease, Choline Dehydrogenase, Mitochondrial | Altered Intercellular Communication | In view of recent evidence that serum creatinine and dysfunctional apolipoprotein (apo)A-I may serve as inflammation mediators in people with enhanced inflammation, we studied whether or not these molecules were interrelated and associated with coronary heart disease (CHD) likelihood even in subjects without metabolic syndrome (MetS) or type-2 diabetes. | 24094290 |
| Inflammation, Nerve Degeneration | Altered Intercellular Communication | Multiple modified gene transcripts involved in inflammation, cytoprotection, and neurodegeneration were correlated with neurocognitive functioning. | 24094461 |
| Inflammation, Coronary Arteriosclerosis, Atrial Fibrillation by ECG Finding, Coronary Artery Disease | Altered Intercellular Communication | Predictors of postoperative atrial fibrillation in patients with coronary artery disease undergoing cardiopulmonary bypass: a possible role for myocardial ischemia and atrial inflammation. | 24094564 |
| Inflammation, Atrial Fibrillation by ECG Finding, Coronary Arteriosclerosis, osteoclast activating factor, Coronary Artery Disease | Altered Intercellular Communication | To evaluate the preoperative presence of C-reactive protein (CRP) and troponin T(hs-TnT) in patients with coronary artery disease (CAD) undergoing cardiopulmonary bypass (CPB) in order to better clarify the role of atrial inflammation and/or myocardial ischemia in the development of postoperative atrial fibrillation (POAF). | 24094564 |
| Inflammation, Depression, CTCAE | Altered Intercellular Communication | Inflammation is considered as a mechanism leading to depression, but the association between inflammatory dietary pattern and depression risk is unknown. | 24095894 |
| Inflammation, Depression, CTCAE | Altered Intercellular Communication | This finding suggests that chronic inflammation may underlie the association between diet and depression. | 24095894 |
| Shock, Inflammation | Altered Intercellular Communication | Heat shock protein 70 (HSP70) plays a critical role in the process of inflammation and innate immunity response under environmental stress. | 24095952 |
| Inflammation, Primary malignant neoplasm, Necrosis | Altered Intercellular Communication | Therapeutic response was assessed histopathologically as grade 0 to 3, based on the degree of disappearance of cancer cells, displacement by necrotic and fibrotic tissue, and tumor-induced inflammation. | 24096109 |
| Inflammation, Obesity, Pain Distress Question | Altered Intercellular Communication | Association of obesity with inflammation and pain after total hip arthroplasty. | 24096457 |
| Inflammation, Obesity, Pain Distress Question | Altered Intercellular Communication | Larger studies exploring the specific impact of obesity and inflammation on surgical outcomes, including pain, are warranted. | 24096457 |
| Inflammation, Chronic sinusitis | Altered Intercellular Communication | Chronic rhinosinusitis is a symptomatic inflammation of the mucosa of the nose and paranasal sinuses lasting for at least 12 weeks. | 24096817 |
| Inflammation | Altered Intercellular Communication | One lesion was considered a benign finding from inflammation demonstrated by clinical follow-up. | 24096999 |
| Inflammation, Sarcopenia, Osteoporosis | Altered Intercellular Communication | Biological (inflammation, loss of hormones), clinical (sarcopenia, osteoporosis etc. | 24097023 |
| Inflammation, Sarcopenia, Osteoporosis | Altered Intercellular Communication | Biological (inflammation, loss of hormones), clinical (sarcopenia, osteoporosis etc. | 24097023 |
| Inflammation, Overactive bladder syndrome | Altered Intercellular Communication | Increased serum adipokines implicate chronic inflammation in the pathogenesis of overactive bladder syndrome refractory to antimuscarinic therapy. | 24098552 |
| Inflammation, Overactive Bladder | Altered Intercellular Communication | Recent studies have shown that chronic inflammation is involved in overactive bladder (OAB) syndrome. | 24098552 |
| Neurogenic Inflammation | Altered Intercellular Communication | OAB could be a subtype of neurogenic inflammation. | 24098552 |
| Inflammation | Altered Intercellular Communication | Adiponectin plays an important role in the regulation of tissue inflammation. | 24099881 |
| Inflammation, Fibrosis Assessment, Hypertrophy | Altered Intercellular Communication | We aimed to investigate telomere length in whole adipose tissue and isolated adipocytes in relation to adiposity, adipocyte hypertrophy and adipose tissue inflammation and fibrosis. | 24100424 |
| Inflammation, Units Of Measure - Siemens | Altered Intercellular Communication | Our results suggest that maintenance of high mitochondrial transcription and lack of inflammation in SAT are associated with low liver fat and MHO. | 24100782 |
| Stomach Carcinoma, Gastritis | Altered Intercellular Communication | In conclusion, functional polymorphisms of NFKB1 are associated with an increased risk of gastric cancer; in particular they are closely associated with the development of diffuse type of gastric cancer via severe gastric inflammation. | 24101096 |
| Inflammation, GDC Disease Response Terminology | Altered Intercellular Communication | The results require confirmation but are consistent with greater hypercoagulabilty and inflammation, as measured by higher levels of PAI-1 and fibrinogen, being related to DR and responsiveness to INT. | 24101699 |
| Inflammation, Swelling, Edema | Altered Intercellular Communication | Corticosteroid transdermal delivery to target swelling, edema and inflammation following facial rejuvenation procedures. | 24101860 |
| Inflammation, Swelling, Edema | Altered Intercellular Communication | The present study supports the use of Betesil(r) plaster immediately after facial cosmetic procedures in order to safely control swelling, edema, and inflammation. | 24101860 |
| Inflammation, Fibrosis Assessment, Coronary Artery Disease | Altered Intercellular Communication | Galectin-3, as a biomarker of inflammation and fibrosis, has been reported to be associated with coronary artery disease. | 24102091 |
| ARCN1 gene, Inflammation, Exacerbation | Altered Intercellular Communication | COPD is characterized by systemic inflammation, which is enhanced during exacerbations and may be assessed by measuring serum C-reactive protein (CRP). | 24102428 |
| Neoplasms | Altered Intercellular Communication | We found that tumour size, tumour weight, hormonal function and the Weiss system are all high-efficacy criteria for differentiating malignant from benign tumours (P < 0.001). | 24102952 |
| Inflammation, Ulceration, CTCAE, Scab | Altered Intercellular Communication | Monitoring during imiquimod treatment revealed impaired image quality most likely caused by inflammation, crusting and ulceration. | 24103017 |
| Inflammation, Neoplasms, Venous Invasion | Altered Intercellular Communication | Infiltration of T-cells was related to early tumour stage, expanding growth pattern and lower levels of venous invasion but was not influenced by host characteristics or degree of systemic inflammation. | 24103145 |
| Inflammation, Lipoma | Altered Intercellular Communication | These facts suggested some possibility of the relationship between inflammation and the occurrence, growth of lipoma. | 24105121 |
| Inflammation | Altered Intercellular Communication | Magnetic resonance scanning revealed a marked increase in inflammation of the brainstem (Figure 1c). | 24105316 |
| Inflammatory Bowel Diseases, Inflammation | Altered Intercellular Communication | Association of circulating vitamin D concentrations with intestinal but not systemic inflammation in inflammatory bowel disease. | 24105392 |
| Gastrointestinal inflammation | Altered Intercellular Communication | Despite total, free, and bioavailable 25(OH)D concentrations being similar to those in a healthy control population, they inversely correlated strongly with intestinal inflammation. | 24105392 |
| Inflammation, Cholelithiasis | Altered Intercellular Communication | Patients (n = 122) with symptomatic gallstone disease, intact papilla and no ongoing inflammation, were prospectively enrolled in this case-control designed study. | 24106403 |
| Inflammation | Altered Intercellular Communication | IL-33, a newly found cytokine which is involved in joint inflammation, could be blocked by a decoy receptor-sST2. | 24106520 |
| Periodontitis, Coronary heart disease | Altered Intercellular Communication | Periodontitis is the most common chronic inflammatory condition worldwide and is associated with incident coronary disease. | 24106721 |
| Cardiac valve calcification, Periodontal Diseases | Altered Intercellular Communication | In a multiracial population, we found a significant association between the degree of periodontal disease, a chronic inflammatory condition, and cardiac calcification. | 24106721 |
| Multiple Organ Failure, Inflammation, Observation Method - Coagulation, Disseminated Intravascular Coagulation, SLC25A10 gene | Altered Intercellular Communication | Disseminated intravascular coagulation (DIC) and multiple organ failure often occur via the crosstalk between inflammation and coagulation, which is mediated by High Mobility Group Box 1 (HMGB1). | 24107274 |
| Inflammation, Restenosis, Vascular System Injuries | Altered Intercellular Communication | We hypothesized that mechanical stress imposed on the stent edge would cause vessel wall injury and inflammation, which may consequently lead to edge restenosis. | 24107326 |
| Inflammation, Ischemic stroke | Altered Intercellular Communication | Increasing evidence shows that inflammation plays an important role in the occurrence and progression of acute ischemic stroke. | 24107402 |
| Inflammation, Cerebrovascular accident | Altered Intercellular Communication | The polymorphisms at -374 and -429 loci did not influence the stroke risk and the above mentioned inflammation cytokines. | 24107402 |
| Inflammation, Ileitis, Crohn Disease | Altered Intercellular Communication | We aimed to evaluate the de novo inflammation developing in the ileal pouch, hypothesizing that it may be similar to ileitis in Crohn's disease (CD). | 24108111 |
| Inflammation, Tuberculosis, Leishmaniasis | Altered Intercellular Communication | Gene ontology analyses revealed multiple biological processes associated with pouch inflammation, including response to chemical stimulus, small molecule metabolic and immune system processes, and specific infection-related pathways such as Staphylococcus aureus, leishmaniasis, and tuberculosis. | 24108111 |
| Inflammatory Bowel Diseases, Inflammation | Altered Intercellular Communication | Gene alterations in pouch inflammation and CD overlap, suggesting that inflammatory bowel diseases is a spectrum, rather than distinct diseases. | 24108111 |
| Psychotic Disorders, Inflammation, Heart Diseases, Rheumatoid Arthritis, Juvenile psoriatic arthritis, Dissociative disorder, Delirium | Altered Intercellular Communication | Juvenile psoriasis was associated with numerous significant comorbidities such as rheumatoid arthritis and inflammation (2.1%); delirium, psychosis, and psychotic and dissociative disorder (1.1%); and heart disease (0.6%). | 24111584 |
| Inflammation, Pneumonia | Altered Intercellular Communication | Previous studies suggest that dendritic cells and macrophages play an important role in inflammation of eosinophilic pneumonia. | 24111618 |
| Inflammation, Fibrosis Assessment | Altered Intercellular Communication | In the NCRT group, patents with moderate to severe fibrosis or grade 2 inflammation had poorer survival than those with mild fibrosis (P = 0.04) or those with grade 0 or grade 1 inflammation (P = 0.003), respectively. | 24111684 |
| Fibrosis of pancreas, Cell Aggregation, Inflammation | Altered Intercellular Communication | Non-neoplastic pancreatic tissue from patients who received NCRT had a reduced density of high-grade PanIN lesions, more pancreatic fibrosis, and higher frequencies of neuroma-like nerve proliferation and islet cell aggregation, but less inflammation, compared to tissue from those who did not receive NCRT. | 24111684 |
| Inflammation | Altered Intercellular Communication | Increase in intraocular pressure (IOP) at the time of inflammation was seen in 10 cases (27.78%). | 24111839 |
| ARCN1 gene, Inflammation, Chronic Obstructive Airway Disease | Altered Intercellular Communication | Cigarette smoke induces an acute but persisting inflammation in peripheral blood and airway in chronic obstructive pulmonary disease (COPD), and CD8(+) Tc-lymphocytes are considered as a key role in this process. | 24112150 |
| Delirium, Inflammation | Altered Intercellular Communication | The relationship between inflammation and delirium remains to be determined. | 24112153 |
| Inflammation, Choline Dehydrogenase, Mitochondrial | Altered Intercellular Communication | However, whether this phenomenon persists in CHD patients, a disease related to inflammation, is unknown. | 24112159 |
| Inflammation, Hyaline degeneration, Neoplasms, Dense fibrous connective tissue, Osteogenesis, Calcinosis | Altered Intercellular Communication | Pathological examination yielded a diagnosis of fibrous connective tissue with hyaline degeneration, calcification and ossification with no indication of neoplasia or inflammation. | 24112395 |
| Inflammation | Altered Intercellular Communication | Unlike other ICK cases in which there is minimal stromal inflammation, the patient presented with an intense inflammatory reaction in the anterior chamber. | 24113463 |
| Arthralgia, Inflammation | Altered Intercellular Communication | Strenuous, high-volume exercise is often associated with inflammation and joint pain. | 24113700 |
| Inflammation | Altered Intercellular Communication | Immune cell-mediated inflammation and the early improvements in glucose metabolism after gastric banding surgery. | 24114113 |
| Inflammation | Altered Intercellular Communication | We hypothesised that early changes in glucose metabolism following gastric banding surgery may relate to systemic inflammation, particularly cell-mediated immunity. | 24114113 |
| Inflammation, Diabetes Mellitus, Non-Insulin-Dependent | Altered Intercellular Communication | The contribution of immune cell-mediated inflammation to glucose homeostasis in type 2 diabetes and its improvement after bariatric surgery require further investigation. | 24114113 |
| Inflammation, atherosclerotic | Altered Intercellular Communication | Combined 18F-FDG PET-CT and DCE-MRI to assess inflammation and microvascularization in atherosclerotic plaques. | 24114456 |
| Inflammation, atherosclerotic | Altered Intercellular Communication | This study determines whether there is a correlation between inflammation and neovascularization in atherosclerotic carotid plaques. | 24114456 |
| Inflammation | Altered Intercellular Communication | The pathophysiology of this syndrome may relate to overuse and inflammation. | 24114651 |
| Diarrhea, Oral pain, Nausea, Inflammatory disease of mucous membrane, Fatigue | Altered Intercellular Communication | The most frequently occurring adverse events were nausea, oral pain, fatigue, diarrhea, and mucosal inflammation. | 24114811 |
| Inflammation, Primary malignant neoplasm, Nasopharyngeal carcinoma, Rhinosinusitis | Altered Intercellular Communication | Although it is already known that the inflammation process elevates the risk of developing cancer, to date the association between rhinosinusitis and nasopharyngeal carcinoma (NPC) remains unknown. | 24114992 |
| Urinary tract infection, Diabetes Mellitus | Altered Intercellular Communication | Preliminary results suggest that UTI levels could represent a useful marker of chronic inflammatory condition in type 1 and 2 diabetes. | 24115191 |
| Metabolic Diseases, Gastrointestinal inflammation | Altered Intercellular Communication | Strict vegetarian diet improves the risk factors associated with metabolic diseases by modulating gut microbiota and reducing intestinal inflammation. | 24115628 |
| Inflammation, physiopathological, Dysbiosis | Altered Intercellular Communication | Low-grade inflammation of the intestine results in metabolic dysfunction, in which dysbiosis of the gut microbiota is intimately involved. | 24115628 |
| Inflammation, Metabolic Diseases | Altered Intercellular Communication | This study underscores the benefits of dietary fibre for improving the risk factors of metabolic diseases and shows that increased fibre intake reduces gut inflammation by changing the gut microbiota. | 24115628 |
| Inflammation, Reperfusion Injury | Altered Intercellular Communication | Beyond this, McCord's career is distinguished for bridging the gap from basic science to clinical relevance by showing the application of SOD and superoxide to human physiology, and characterizing the physiological functions of superoxide in inflammation, immunological chemotaxis, and ischemia-reperfusion injury, among other disease conditions. | 24117164 |
| Celiac Disease, Gastrointestinal inflammation | Altered Intercellular Communication | The majority of deleterious health consequences of coeliac disease (CD) are most likely to be secondary to intestinal inflammation; hence, mucosal recovery is a desirable goal of therapy. | 24117503 |
| Inflammation | Altered Intercellular Communication | This defect in mucosal immunity is associated with eosinophilic, Th2-related inflammation. | 24117840 |
| Localized scleroderma, Inflammation, Scleroderma | Altered Intercellular Communication | Perineural inflammation in morphea (localized scleroderma): systematic characterization of a poorly recognized but potentially useful histopathological feature. | 24117981 |
| Localized scleroderma, Inflammation | Altered Intercellular Communication | The association between morphea and perineural inflammation has been reported sporadically but never studied systematically. | 24117981 |
| Localized scleroderma, Inflammation | Altered Intercellular Communication | Perineural inflammation was identified in 84% and 61% of morphea and control cases, respectively. | 24117981 |
| Localized scleroderma, Inflammation | Altered Intercellular Communication | Mean perineural inflammation score in morphea (0.65) was significantly higher than in the control group (0.23) (p < 0.0001) and the inflammation tended to show a concentric pattern with plasma cell neurotropism. | 24117981 |
| Localized scleroderma, Inflammation | Altered Intercellular Communication | Intraneural inflammation was limited to four morphea cases. | 24117981 |
| Localized scleroderma, Inflammation | Altered Intercellular Communication | Although perineural inflammation is common in morphea, it is not unusual to find this feature in other inflammatory conditions. | 24117981 |
| Localized scleroderma, Inflammation | Altered Intercellular Communication | Nevertheless, perineural inflammation can serve as an important diagnostic adjunct in difficult cases of morphea if one considers its greater intensity, predominantly concentric pattern and the tendency to show plasma cell neurotropism. | 24117981 |
| Localized scleroderma, Inflammation | Altered Intercellular Communication | Although perineural inflammation is common in morphea, it is not unusual to find this feature in other inflammatory conditions. | 24117981 |
| Psoriatic Juvenile Idiopathic Arthritis, Inflammation | Altered Intercellular Communication | Psoriatic patients are at greater risk of oxidative stress and inflammation which is associated with abnormal plasma lipid metabolism and lipid peroxidation.There is not any information about the clinical significance of relation between methylentetrahydrofolatereductase (MTHFR) 677-T allele with malondialdehyde (MDA), lipids, apolipoproteins and vascular adhesion protein-1 (VAP-1) partakes in the migration process of lymphocytes into sites of inflammation. | 24118377 |
| Inflammation, Chronic Kidney Diseases, Cardiovascular Diseases | Altered Intercellular Communication | Chronic systemic inflammation, a non traditional risk factor of cardiovascular diseases, is associated with increasing mortality in chronic kidney disease, especially peritoneal dialysis patients. | 24118730 |
| Inflammation, Periodontitis | Altered Intercellular Communication | Periodontitis is a potential treatable source of systemic inflammation in peritoneal dialysis patients. | 24118730 |
| Inflammation, Periodontitis | Altered Intercellular Communication | Periodontitis is an important source of chronic systemic inflammation in peritoneal dialysis patients. | 24118730 |
| Inflammation, Periodontal Diseases | Altered Intercellular Communication | Treatment of periodontal diseases can improve systemic inflammation, nutritional status and erythropoietin responsiveness in peritoneal dialysis patients. | 24118730 |
| Inflammation, Neoplasms | Altered Intercellular Communication | MicroRNA-218 (miR-218) can function as a tumour suppressor and inactivate cancer-promoting inflammation. | 24118778 |
| Ulcerative Colitis | Altered Intercellular Communication | This may cause increased proliferation of C-cell cultures, a defining initiating feature in the inflammation-carcinoma pathway in UC. | 24118792 |
| Inflammatory abnormality of the eye | Altered Intercellular Communication | Visual acuity, intraocular pressure, corneal thickness, corneal endothelial cell and ocular inflammation were examined. | 24119034 |
| Fibrinoid necrotizing inflammation, Destruction (action) | Altered Intercellular Communication | This factor may have a pathological role in RA joint destruction caused by PMNs and coinciding with rheumatoid inflammation, which suggests that PMNs, via superoxide generation, play an important role in RA joint destruction. | 24119062 |
| Inflammation, Chronic Kidney Diseases | Altered Intercellular Communication | Hepcidin has emerged as a peptide with a key role in the regulation of iron homeostasis in patients with chronic kidney disease (CKD), having a strong dependence on inflammation. | 24119290 |
| Inflammation, hepcidin, Atherosclerosis | Altered Intercellular Communication | This study was performed to analyze the relation of hepcidin to markers of atherosclerosis and inflammation in patients on dialysis. | 24119290 |
| Inflammation, hepcidin, Atherosclerosis | Altered Intercellular Communication | This probably suggests that hepcidin may play a role to the progression of atherosclerosis and inflammation, but this hypothesis should be further evaluated. | 24119290 |
| Autoimmune Diseases, "Sjogrens Syndrome", Xerostomia, Keratoconjunctivitis Sicca, Chronic lymphocytic inflammation | Altered Intercellular Communication | Primary Sjogren's syndrome is an autoimmune disease that presents with xerostomia and keratoconjunctivitis sicca (due to chronic lymphocytic inflammation of the salivary and lacrimal glands) and in some cases extraglandular features. | 24119527 |
| Inflammation, Chronic sinusitis, Craniosynostosis | Altered Intercellular Communication | Chronic rhinosinusitis (CRS) is characterized by inflammatory cell migration into sinus tissue with resultant inflammation fueled by a milieu of cytokines. | 24119601 |
| Inflammation | Altered Intercellular Communication | Fibroblasts may contribute to inflammation through expression of leukocyte adhesion molecules such as vascular cell adhesion molecule (VCAM) and intercellular adhesion molecule (ICAM). | 24119601 |
| Inflammation, Data types - Address | Altered Intercellular Communication | However, a bubble is expected to entrap Nitric Oxide (NO), which leads theoretically to a decrease in its bioavailability, and is expected to trigger a guanylyl-cyclase-mediated inflammatory cascade, that could explain the inflammation in AD. | 24119763 |
| Inflammation, Complex Regional Pain Syndromes, Dystonia Disorders | Altered Intercellular Communication | Our findings point at a catabolic state in chronic CRPS patients with dystonia that is likely associated with inflammation. | 24120462 |
| Inflammation, Cerebral Hemorrhage | Altered Intercellular Communication | Visfatin is linked to inflammation and associated with clinical outcomes of intracerebral hemorrhage. | 24120704 |
| Airway structure, Asthma | Altered Intercellular Communication | Chronic airway inflammation is a central process in asthma. | 24121577 |
| Airway structure | Altered Intercellular Communication | Measurement of exhaled nitric oxide (eNO) is a non-invasive biomarker of eosinophilic airway inflammation. | 24121577 |
| Inflammation, Hypopituitarism | Altered Intercellular Communication | Patients were treated by high-dose corticosteroid therapy resulting in the resolution of local inflammation but not of pituitary deficiencies. | 24122241 |
| Inflammation | Altered Intercellular Communication | This effect modification suggests that the impact of chronic inflammation may be independent of excess body fat. | 24122448 |
| Colitis | Altered Intercellular Communication | Future research is recommended to confirm emerging data that elevated serologic CRP might reflect underlying colonic inflammation. | 24122448 |
| Malignant tumor of colon, Inflammation | Altered Intercellular Communication | AIM/ BACKGROUND: The neutrophil-to-lymphocyte ratio (NLR), a combined indicator of inflammation and immunology, is as yet unidentified regarding the clinical outcome of stage II and III colon cancer patients. | 24123035 |
| Inflammation, Metabolic Diseases, Obesity | Altered Intercellular Communication | Influenced by pathogen exposure and obesity, inflammation provides a critical biological pathway linking changing environments to the development of cardiometabolic disease. | 24123588 |
| Communicable Diseases, Inflammation, Acute inflammation, Overweight | Altered Intercellular Communication | History of infectious (RRR 1.28, 95%CI 1.08-1.52) and non-communicable (RRR 1.37, 95%CI 1.12-1.69) disease, overweight (RRR 1.66, 95%CI 1.45-1.89) and high waist circumference (RRR 1.63, 95%CI 1.42-1.87) were independently associated with a greater likelihood of moderate inflammation in adults while history of infectious disease (RRR 1.87, 95%CI 1.35-2.56) and overweight (RRR 1.40, 95%CI 1.04-1.88) were independently associated with acute inflammation. | 24123588 |
| Inflammation | Altered Intercellular Communication | Environmental pathogenicity was associated with a reduced likelihood of moderate inflammation, but a greater likelihood of acute inflammation in adults. | 24123588 |
| Inflammation, Stomach Carcinoma | Altered Intercellular Communication | SNP rs2447867 might be related to the severity of gastric epithelial injury due to inflammation and, thus, to the risk of developing gastric cancer. | 24124332 |
| Inflammation | Altered Intercellular Communication | Increasing evidence indicates that inflammation is important in disease pathophysiology. | 24124488 |
| Pneumonitis | Altered Intercellular Communication | Future research should determine whether NF-kB activation is a driver or bystander of pulmonary vascular inflammation and if the former, its potential role as a therapeutic target. | 24124488 |
| Sepsis, Inflammation | Altered Intercellular Communication | Its importance in inflammation and human sepsis is unknown. | 24124588 |
| Sepsis, Inflammation | Altered Intercellular Communication | Further studies are required to clarify the role of the N/OFQ system in inflammation and sepsis, and the mechanisms involved. | 24124588 |
| glycation, vascular inflammations, Atherosclerosis | Altered Intercellular Communication | The receptor for advanced glycation end products (RAGE) has emerged as a central regulator of vascular inflammation and atherosclerosis. | 24124651 |
| HD Term Type, Inflammation | Altered Intercellular Communication | This study demonstrated that the circulating sRAGE level was inversely associated with VCS in HD patients independent of the S100A12 level and the severity of systemic inflammation. | 24124651 |
| Venous Thromboembolism | Altered Intercellular Communication | [Dynamic changes of inflammation-related indices in venous thromboembolism and the association between these indices and venous thromboembolism]. | 24124734 |
| Venous Thromboembolism, vinyltriethoxysilane | Altered Intercellular Communication | To evaluate the dynamic changes of inflammation-related indices in blood during the development of venous thromboembolism (VTE) and the association between these indices and VTE. | 24124734 |
| vinyltriethoxysilane | Altered Intercellular Communication | Some inflammation-related indices frequently used in clinical settings become elevated in VTE patients. | 24124734 |
| Inflammation, Tumor necrosis, Obesity | Altered Intercellular Communication | Body image dissatisfaction uniquely predicted inflammation biomarkers, C-reactive protein and tumour necrosis factor-a, even when controlled for obesity indicators. | 24125028 |
| Inflammation | Altered Intercellular Communication | Results contribute to the knowledge base of the complex pathways in the association between psychological factors and physical illness and some important attempts were made to explain the psychological pathways linking cognitions with inflammation. | 24125028 |
| Inflammation | Altered Intercellular Communication | The causes are not fully known, but inflammation plays a pathogenic role. | 24125405 |
| Inflammatory disease of mucous membrane | Altered Intercellular Communication | Biomarkers reflective of mucosal and bowel wall inflammation would be useful to monitor disease activity. | 24126633 |
| Inflammation, Ulcerative Colitis | Altered Intercellular Communication | Combinations of fecal calprotectin and serum MMP9 for UC, and combinations of fecal calprotectin, serum MMP9, and serum interleukin-22 in CD, demonstrated the strongest association with imaging/endoscopy-defined inflammation. | 24126633 |
| Diastolic dysfunction, Inflammation | Altered Intercellular Communication | We hypothesized that serum 25-hydroxyvitamin D [25(OH)D] levels would be inversely associated with inflammation and with diastolic dysfunction. | 24126766 |
| Inflammation, atherosclerotic, Necrosis | Altered Intercellular Communication | Rupture-prone atherosclerotic plaques are characterized by inflammation and a large necrotic core. | 24126878 |
| Inflammation, Dental Plaque, Necrosis | Altered Intercellular Communication | Therefore, we investigated whether plaque AGEs are increased in human carotid rupture-prone plaques and are associated with plaque inflammation and necrotic core formation. | 24126878 |
| Inflammation | Altered Intercellular Communication | Furthermore, this study suggests a cascade linking inflammation, reduced GLO-1, methylglyoxal- and AGE-accumulation, and subsequent apoptosis. | 24126878 |
| Refractory anemias, Inflammation | Altered Intercellular Communication | These data suggest that HTLV-I-positive patients with RA had higher inflammation and greater resistance to anti-TNF treatment than HTLV-I-negative patients. | 24127184 |
| Inflammation, Pain Distress Question, Rheumatoid Arthritis, Depression, CTCAE, Alexithymia | Altered Intercellular Communication | Alexithymia, depression, inflammation, and pain in patients with rheumatoid arthritis. | 24127403 |
| Inflammation, Pain Distress Question, Refractory anemias, Rheumatoid Arthritis, Depression, CTCAE | Altered Intercellular Communication | We previously reported that depression and inflammation have independent effects on pain severity in patients with rheumatoid arthritis (RA). | 24127403 |
| Alexithymia, Inflammation, Depression, CTCAE, Pain Distress Question | Altered Intercellular Communication | A broad association between alexithymia and various health problems has been suggested, including depression, inflammation, and pain. | 24127403 |
| Alexithymia, Inflammation, Depression, CTCAE, Pain Distress Question | Altered Intercellular Communication | The objective of this study was to examine the independent influence of alexithymia on pain perception and its relationship to depression and inflammation. | 24127403 |
| Alexithymia, Inflammation, Depression, CTCAE, Pain Distress Question | Altered Intercellular Communication | An interaction was observed among alexithymia, depression, and inflammation with regard to perceived pain. | 24127403 |
| Inflammation, Diffuse alveolar hemorrhage, Capillaritis | Altered Intercellular Communication | Causes of distal or diffuse alveolar hemorrhage are divided by the histologic presence or absence of capillaritis, which is characterized by inflammation of the alveolar interstitium and pulmonary capillary structure. | 24127476 |
| Inflammation | Altered Intercellular Communication | The epidermal growth factor also plays an important role in regulating multiple facets of cutaneous wound healing, including inflammation, wound contraction, proliferation, migration, and angiogenesis. | 24127898 |
| Inflammation, Psoriasis, Precocious atherosclerosis | Altered Intercellular Communication | Severe psoriasis has been associated with increase cardiovascular mortality, due to a higher prevalence of traditional cardiovascular risk factors and premature atherosclerosis, as a consequence of its systemic inflammation. | 24128349 |
| Inflammation, Epilepsy | Altered Intercellular Communication | Inflammation and iron metabolism in adult patients with epilepsy: does a link exist? | 24128993 |
| Inflammation, Epilepsy | Altered Intercellular Communication | Inflammation has been shown to play a key role in epilepsy, and may also affect both the iron status and metabolism. | 24128993 |
| Seizures, Inflammation, Epilepsy | Altered Intercellular Communication | Our findings demonstrate a relevant relationship between epilepsy and systemic inflammation, with a consistent link between seizures, inflammatory cytokines (IL-6 and TNF-a) and iron regulation and metabolism, as acute phase and antioxidant markers. | 24128993 |
| Tuberculosis of other urinary organs, Cancer of Urinary Tract, Urinary tract obstruction, Acute and chronic inflammation | Altered Intercellular Communication | Urinary tuberculosis (UTB) can cause chronic urinary tract inflammation, lead to obstructive uropathy, and potentially contribute to the development of urinary tract cancer. | 24129236 |
| Inflammation, Neoplasms | Altered Intercellular Communication | This multiple-receptor inhibition may explain why the peptide was also seen to be a powerful inhibitor of tumour growth and also a partial inhibitor of arthritic joint inflammation in vivo. | 24129822 |
| Inflammation, Obesity | Altered Intercellular Communication | During obesity, chronic inflammation of human white adipose tissue (WAT) is associated with metabolic and vascular alterations. | 24130331 |
| Inflammation, Morbid obesity | Altered Intercellular Communication | Therapeutic options targeting EC inflammation could prevent adipocyte alterations that contribute to obesity comorbidities. | 24130331 |
| Inflammation | Altered Intercellular Communication | Haptoglobin (Hp) is an acute phase protein, the synthesis of which is increased during inflammation. | 24130793 |
| Hepatocarcinogenesis, Hepatitis C, Hepatitis B, Chronic, Immune-mediated | Altered Intercellular Communication | Mechanisms of hepatic carcinogenesis in chronic hepatitis B and hepatitis C are incompletely defined but often assumed to be similar and related to immune-mediated inflammation. | 24130799 |
| Inflammatory Bowel Diseases, Inflammation | Altered Intercellular Communication | Loss of ANXA1 expression may support inflammation during IBD and can serve as a biomarker of disease progression. | 24130820 |
| Gastroesophageal reflux disease, Pharyngitis, Gorontalo Language | Altered Intercellular Communication | The more modern terms, globus sensation or globus pharyngeus, reflect recognition of one or more possible contributing anatomico-physiological factors, such as gastro-oesophageal reflux disease (GORD) or pharyngeal inflammation. | 24130967 |
| Inflammation, Disorders of Porphyrin Metabolism, Arthropathy | Altered Intercellular Communication | Chronic inflammation related to this patient's seronegative arthropathy, although atypical for porphyria, might have contributed to the development of AA amyloidosis. | 24131077 |
| Inflammation, Congestive heart failure | Altered Intercellular Communication | Inflammation is part of the pathophysiology of congestive heart failure (CHF). | 24131549 |
| Inflammation | Altered Intercellular Communication | In EHOA patients ANCA and anti-CCP antibodies might be either markers of inflammation involving neutrophils and/or markers of an underlying autoimmune process. | 24131910 |
| Inflammation, Calcinosis | Altered Intercellular Communication | Calcinosis has been associated with inflammation but information about its pathogeny continues to evolve as we learn more about the underlying processes. | 24131911 |
| Communicable Diseases, Inflammation | Altered Intercellular Communication | Although markers of inflammation and insulin resistance are also related to the onset of surgical infection, leptin correlates more closely with the risk of infection than does any other factor. | 24132530 |
| Barrett Esophagus, Carcinoma, Adenocarcinoma Of Esophagus | Altered Intercellular Communication | Esophageal adenocarcinoma (EAC) may develop through a process involving inflammation [reflux esophagitis (RE)] leading to metaplasia [Barrett's esophagus (BE)] and carcinoma. | 24132576 |
| Inflammation, Tissue injury | Altered Intercellular Communication | These data suggest a role for gut mucosal macrophages in HIV immune pathogenesis: infiltrated macrophages in the intestinal mucosa may promote local inflammation and tissue injury, whereas their low phagocytic activity prevents the efficient elimination of luminal antigens that cross the damaged intestinal barrier. | 24133185 |
| Degenerative polyarthritis, Inflammation | Altered Intercellular Communication | We suggest that eosinophilic inflammation may be involved in the pathogenesis of PVC-induced OA and that FeNO monitoring can be used for its diagnosis. | 24133363 |
| Crohn Disease, Non-necrotizing granulomatous inflammation | Altered Intercellular Communication | Metastatic Crohn's disease (CD) is an extremely rare extragastrointestinal manifestation of CD, and is characterized histopathologically by the presence of non-caseating granulomatous inflammation. | 24133609 |
| Granulomatous inflammation, Swelling, gastrointestinal | Altered Intercellular Communication | However, a few cases of genital swelling associated with granulomatous inflammation prior to a diagnosis of gastrointestinal CD have been documented. | 24133609 |
| Inflammation | Altered Intercellular Communication | Abnormalities of liver function tests in Kawasaki disease patients may occur as a result of inflammation of both the biliary and portal systems. | 24134764 |
| Inflammation, Metabolic Syndrome X, Obesity | Altered Intercellular Communication | Comparing the highest with the lowest quintiles of dietary fiber intake, adjusted predicted marginal risk ratios (95% confidence interval) for the metabolic syndrome, inflammation, and obesity were 0.78 (0.69-0.88), 0.66 (0.61-0.72), and 0.77 (0.71-0.84), respectively. | 24135514 |
| Noninfiltrating Intraductal Carcinoma | Altered Intercellular Communication | Despite an evident lack of power, this study elicited neuroregulin 1, a vasoreactivity-, inflammation- and angiogenesis-related gene, as a possible candidate predictor of DCI. | 24135536 |
| Communicable Diseases, Inflammation, Bronchiectasis | Altered Intercellular Communication | In immunocompetent patients with bronchiectasis, key clinico-pathophysiological relationships exist between exacerbation frequency, lung function, health-status, infection and inflammation. | 24136152 |
| Inflammation, Bronchiectasis | Altered Intercellular Communication | It is also not known how local and systemic inflammation in PAD compares with that in immunocompetent (non-PAD) bronchiectasis patients. | 24136152 |
| Communicable Diseases, Inflammation, Bronchiectasis | Altered Intercellular Communication | We assessed symptoms, exacerbation frequency, health-status, lung function, CT, airway and systemic inflammation and infection in 33 PAD patients and 20 immunocompetent controls with bronchiectasis. | 24136152 |
| Inflammation | Altered Intercellular Communication | Despite less severe airflow obstruction, PAD patients had similar health-status impairment and greater airway (sputum log10 IL-6 2.71 vs. 1.81 pg/ml, p = 0.001) and greater systemic inflammation than immunocompetent bronchiectasis controls (serum log10 CRP 0.77 vs. 0.36 mg/l, p = 0.001). | 24136152 |
| Inflammation, Bronchiectasis | Altered Intercellular Communication | Finally, patients with PAD had greater airway and systemic inflammation than a control population with non-PAD bronchiectasis which may suggest a dysregulated airway immune response. | 24136152 |
| Inflammation, Asthma | Altered Intercellular Communication | NLRP3 inflammasome is upregulated in neutrophilic asthma and may regulate the inflammation process observed in this asthma phenotype through production of IL-1b. | 24136334 |
| Inflammation, Lymphoma, Neoplasms | Altered Intercellular Communication | Other changes were for lymphoma vs inflammation or lymphoma typing (n = 89) and for confirmation of or change in tumor type for benign (n = 36) or malignant (n = 69) tumors. | 24136579 |
| Steatohepatitis, Inflammation, Metabolic Syndrome X, Prehypertension | Altered Intercellular Communication | Prehypertension is associated with an increased prevalence of metabolic syndrome, hepatic steatosis and subclinical inflammation. | 24136756 |
| Inflammation, Eosinophilic granulomatosis with polyangiitis, Vasculitis, CTCAE | Altered Intercellular Communication | Churg-Strauss syndrome (CSS) is an anti-neutrophil cytoplasmic antibody (ANCA) associated vasculitis; it is extremely rare in childhood and defined according to the Chapel-Hill Consensus as an eosinophil-rich and granulomatous inflammation involving the respiratory tract and necrotizing vasculitis affecting small to medium-sized vessels. | 24136903 |
| Inflammation, Hypertension, CTCAE, Diabetes Mellitus | Altered Intercellular Communication | CVD risk factor prevalence at follow-up ranged from 5.5% (diabetes) to 26.4% (hypertension) and 31.3% (inflammation); risk differed across BMI trajectories. | 24136924 |
| Inflammation, Psoriasis, Cardiovascular Diseases | Altered Intercellular Communication | Risk factors for cardiovascular disease in psoriasis: relation to inflammation assessed by the severity and duration of illness. | 24138074 |
| Inflammation, Psoriasis | Altered Intercellular Communication | To evaluate the epidemiological profile of patients with psoriasis, focusing on the risk factors for CVDs and inflammation. | 24138074 |
| Inflammation, HIV Infections | Altered Intercellular Communication | Systemic effects of inflammation on health during chronic HIV infection. | 24138880 |
| Inflammation, HIV Infections | Altered Intercellular Communication | Many markers of inflammation are elevated in HIV disease and strongly predictive of the risk of morbidity and mortality. | 24138880 |
| Inflammation | Altered Intercellular Communication | A conceptual model has emerged to explain this syndrome of diseases where HIV-mediated destruction of gut mucosa leads to local and systemic inflammation. | 24138880 |
| Inflammation | Altered Intercellular Communication | The combined effect of systemic inflammation and excess clotting on tissue function leads to end-organ disease. | 24138880 |
| Inflammation, HIV Infections, Chronic inflammatory disorder | Altered Intercellular Communication | It is likely that knowledge gained on how inflammation affects health in HIV disease could have implications for our understanding of other chronic inflammatory diseases and the biology of aging. | 24138880 |
| Inflammation, Carcinoma of lung | Altered Intercellular Communication | Evidence is accumulating that chronic inflammation may have an important mechanism for the development and progression of lung cancer. | 24139238 |
| Inflammation, Carcinoma of lung | Altered Intercellular Communication | Future studies involving larger control and case populations will undoubtedly lead to a more thorough understanding of the role of the polymorphisms involved in the inflammation pathway in lung cancer. | 24139238 |
| Scab, Earache, Hearing Loss, Partial, Inflammation | Altered Intercellular Communication | Itching, otalgia, and hypoacusis were the symptoms reported by the patients and the apparent signs were debris in the ear, scabs and inflammation of the external auditory meatus. | 24139621 |
| Tumor necrosis, Inflammation | Altered Intercellular Communication | Tumor necrosis factor a (TNFa) plays a key role in orchestrating the complex events involved in inflammation and immunity. | 24139907 |
| Inflammation, Fatty Liver Disease | Altered Intercellular Communication | Despite similar circulating irisin levels between NAFL and NASH groups, irisin may be independently and positively associated with the presence of portal inflammation. | 24140091 |
| Inflammation, Endothelial dysfunction | Altered Intercellular Communication | Biomarkers of neurohormonal stimulation, inflammation, and endothelial dysfunction were measured. | 24140097 |
| Inflammation, Refractory anemias, Spinal stenosis of lumbar region, Facet joint arthrosis, Spondylitis | Altered Intercellular Communication | Lumbar canal stenosis in RA is caused not only by degeneration but also by RA-related spondylitis, which includes facet arthritis and inflammation around the vertebral endplate. | 24140780 |
| Inflammation | Altered Intercellular Communication | The etiology of this condition is not well understood; however, it is a form of chronic irritation and inflammation. | 24141102 |
| Inflammation, Diabetes Mellitus | Altered Intercellular Communication | A lymphocyte association with incident diabetes, which was the strongest association among the major white cell types, was partially explained by insulin sensitivity rather than subclinical inflammation. | 24141640 |
| Inflammation, Nasal Polyps, Common Cold, Allergic | Altered Intercellular Communication | Although polyps seem to be a manifestation of chronic inflammation of nasal/paranasal sinus mucosa in both allergic and non-allergic subjects, the pathogenesis of nasal polyposis remains unknown. | 24141678 |
| Aggressive course, Inflammation, Hypoxia | Altered Intercellular Communication | Some extremely aggressive cancers are also associated with hypoxia, inflammation and high leukocyte infiltration. | 24141779 |
| Cessation of life, Inflammation | Altered Intercellular Communication | Brain death induces inflammation evidenced by the up-regulation of TNF in serum and pancreatic tissue. | 24142035 |
| Inflammation, Gall Bladder Diseases | Altered Intercellular Communication | Among them, 105 patients with uncomplicated gallbladder disease (no inflammation or no clinical symptoms) and another 105 patients who underwent CLC were selected for this study. | 24142653 |
| Inflammation, Acute Coronary Syndrome | Altered Intercellular Communication | Several inflammation biomarkers have been implicated in the pathogenesis and prognosis of acute coronary syndromes. | 24142685 |
| Photoreceptor degeneration, Atrophic condition of skin, Retinitis | Altered Intercellular Communication | CCR2(+) monocytes infiltrate atrophic lesions in age-related macular disease and mediate photoreceptor degeneration in experimental subretinal inflammation in Cx3cr1 deficient mice. | 24142887 |
| methyldopa, Inflammation, Nerve Degeneration | Altered Intercellular Communication | CCL2/CCR2 inhibition might represent a powerful tool for controlling inflammation and neurodegeneration in AMD. | 24142887 |
| Inflammation, Atrial Fibrillation by ECG Finding | Altered Intercellular Communication | TGF-b1 signal pathway in the regulation of inflammation in patients with atrial fibrillation. | 24144036 |
| Fibrillation, Atrial Fibrillation, Inflammation | Altered Intercellular Communication | AF is associated with inflammation, and the inflammation is also involved in the fibrillation and sustain of AF. | 24144036 |
| Granulomatous inflammation, Unspecified visual loss | Altered Intercellular Communication | The morphological similarity and the anatomical continuity between the meningeal and the perioptic tissues suggest that extension of granulomatous inflammation along such tissue planes accounted for visual loss in these two patients with WG. | 24144064 |
| Inflammation, Nasal Polyps, Granulomatosis, Eosinophilic granulomatosis with polyangiitis, Mononeuritis, Asthma, Hypereosinophilia, Systemic Vasculitis | Altered Intercellular Communication | However, on the basis of the past medical history of nasal polyposis, asthma, and hypereosynophilia as well as of further investigations (biopsy of the nasal mucosa showing granulomatous inflammation with a rich eosinophilic infiltrate, electromyography demonstrating, mononeuritis multiplex and positive p-ANCA), eosinophilic granulomatosis with polyangiitis (EGPA), previously known as Churg-Strauss syndrome, was diagnosed. | 24144341 |
| Inflammation, Demyelination, Trauma, Nervous System, Axonal degeneration, nervous system disorder | Altered Intercellular Communication | Multiple sclerosis (MS) is a neurological disease characterised by central nervous system inflammation, demyelination, axonal degeneration and neuronal injury. | 24144874 |
| Coronary Artery Disease | Altered Intercellular Communication | Coronary artery disease (CAD), as a lipid-driven and inflammation-driven disease, has threatened thousands of patients' lives. | 24146036 |
| Inflammation, Necrosis | Altered Intercellular Communication | The markers were associated with poor histologic type, high grade, necrosis, HR negativity, inflammation, and p53 expression (vessel size only). | 24146798 |
| HIV-1 | Altered Intercellular Communication | Thus, IDO-induced immune-metabolism may be considered as a new inflammation-related marker for HIV-1 disease progression. | 24147117 |
| Inflammation, Atherosclerosis | Altered Intercellular Communication | However, there were no significant changes at T12 between groups N and H following rosuvastatin intake in group H. In conclusion, the quantitative analysis with 18F-FDG-PET/CT could be efficient in the localization of the inflammation and evaluation of its progression in atherosclerosis instead of global evaluations with systemic inflammation biomarkers. | 24148785 |
| Inflammation, Acute Cerebrovascular Accidents | Altered Intercellular Communication | Our results underline the deleterious role of inflammation in acute stroke patients. | 24148838 |
| Inflammation | Altered Intercellular Communication | Subclinical inflammation is detectable with increasing BMI and also WHtR. | 24149444 |
| Inflammation, "Alzheimers Disease | Altered Intercellular Communication | Elevated CNS inflammation in patients with preclinical Alzheimer's disease. | 24149932 |
| Inflammation, Data types - Address | Altered Intercellular Communication | Thus, brain inflammation occurs early at the preclinical stage of AD and may have an important role in pathology. | 24149932 |
| Inflammation | Altered Intercellular Communication | Diet of patients after pouch surgery may affect pouch inflammation. | 24151365 |
| Inflammation, Diverticulitis, Comorbidity | Altered Intercellular Communication | Data were collected with regard to age, sex, albumin level on admission, left or right inflammation site, the history of recurrent diverticulitis, preoperative comorbidity, smoking habits, medication, treatment policy, morbidity, and mortality. | 24151389 |
| Inflammatory disease of mucous membrane | Altered Intercellular Communication | Moderate to severe mucosal inflammation was detected in 60.0% (18/30) of the control group. | 24151905 |
| Gastroesophageal reflux disease, Inflammation, Infection caused by Helicobacter pylori | Altered Intercellular Communication | The etiologies of cardiac inflammation were H. pylori infection and gastroesophageal reflux disease (GERD). | 24151905 |
| Helicobacter pylori Negative, Infection caused by Helicobacter pylori, Inflammatory disease of mucous membrane | Altered Intercellular Communication | For antral H. pylori-negative participants, cardiac mucosal inflammation was correlated with esophageal mucosal inflammation (P < 0.05), while for those with antral H. pylori infection it was associated with antral mucosal inflammation (P < 0.01). | 24151905 |
| Inflammation | Altered Intercellular Communication | Normal-appearing cardiac mucosa under endoscopy might present with histopathologically moderate to severe cardiac inflammation. | 24151905 |
| Gastroesophageal reflux disease, Inflammation, Infection caused by Helicobacter pylori | Altered Intercellular Communication | The etiologies of cardiac inflammation were H. pylori infection and GERD. | 24151905 |
| Inflammation, Optic Neuropathy, Ischemic | Altered Intercellular Communication | Nerve ischemia due to inflammation and microvasculitis has been suggested as the pathophysiological mechanism for DLRPN. | 24152254 |
| Granulomatous inflammation | Altered Intercellular Communication | Histopathological examination revealed granulomatous inflammation in four cases. | 24152503 |
| Communicable Diseases, Acute inflammation, Patellofemoral osteoarthritis | Altered Intercellular Communication | Revision surgery was performed in 24/69 (34.8%) patients and confirmed the SPECT/CT diagnosis in 21 patients (seven loosening, one infection, two subchondral fractures, two postoperative inflammation and nine patellofemoral osteoarthritis). | 24152807 |
| Central Nervous System | Altered Intercellular Communication | Mycoplasma pneumoniae is associated with a variety of extrapulmonary manifestations, including central nervous system inflammation. | 24153008 |
| Inflammation, Chronic sinusitis, Craniosynostosis | Altered Intercellular Communication | Chronic rhinosinusitis (CRS) is characterized by local inflammation of the sinonasal tissues. | 24153332 |
| Inflammation, Diabetes Mellitus, Non-Insulin-Dependent | Altered Intercellular Communication | Diet may be associated with the development of type 2 diabetes through its effects on low-grade inflammation. | 24153342 |
| Inflammation | Altered Intercellular Communication | A higher ADII was associated with a higher summary score for inflammation [b-adjusted = 0.04 per SD (95% CI: 0.01, 0.07 per SD)]. | 24153342 |
| Inflammation, physiopathological | Altered Intercellular Communication | These findings confirm that the potential mechanism of AGEs on pancreatic dysfunction involves the induction of inflammation and the suppression of PDX-1 and GLUT2 expression. | 24154804 |
| Inflammation, Neoplasms | Altered Intercellular Communication | High CLR density associated with better survival and had prognostic value that was independent of stage, Klintrup-Makinen score for peritumoral inflammation and the numbers of tumor infiltrating T cells. | 24154855 |
| Neurogenic Inflammation | Altered Intercellular Communication | PET-scan shows peripherally increased neurokinin 1 receptor availability in chronic tennis elbow: visualizing neurogenic inflammation? | 24155873 |
| Pain Distress Question, Neurogenic Inflammation | Altered Intercellular Communication | The NK1 receptor and its primary agonist, substance P, also play a crucial role in peripheral tissue in response to pain, as part of neurogenic inflammation. | 24155873 |
| Inflammation | Altered Intercellular Communication | The increased NK1 receptor availability is interpreted as part of ongoing neurogenic inflammation and may have correlation to the pathogenesis of chronic tennis elbow. | 24155873 |
| Inflammation, Hypereosinophilia | Altered Intercellular Communication | Skin biopsy revealed dermal inflammation with presence of hypereosinophilia, thereby confirming ACHSS. | 24156229 |
| Alzheimers Disease", Inflammation, Data types - Address | Altered Intercellular Communication | The Alzheimer's disease "inflammation hypothesis" has emerged only recently, suggesting the risk of developing AD might be influenced by variants of genes encoding for inflammatory mediators. | 24156267 |
| Sepsis, Inflammation, Respiratory Distress Syndrome, Adult | Altered Intercellular Communication | Biomarkers of lung epithelial injury and inflammation distinguish severe sepsis patients with acute respiratory distress syndrome. | 24156650 |
| Inflammation, Endothelium | Altered Intercellular Communication | A panel that included 11 biomarkers of inflammation, fibroblast activation, proteolytic injury, endothelial injury, and lung epithelial injury was measured in plasma from the morning of ICU day two. | 24156650 |
| Inflammation, Hypothyroidism | Altered Intercellular Communication | FT3 also had a moderate negative correlation with CRP (r = -0.475, P < 0.001), which might indicate that hypothyroidism may activate the inflammation response. | 24157158 |
| Inflammation, Metabolic Syndrome X, MS gene | Altered Intercellular Communication | Metabolic syndrome (MS) is suggested to be associated with a low grade inflammation state, but the relationship between inflammation biomarkers and the components of metabolic syndrome in adolescents are still lacking. | 24160219 |
| Inflammation, Metabolic Diseases | Altered Intercellular Communication | The association found between individual components of MS and CRP concentrations suggests that inflammation might be an early event in the development of metabolic disorders in adolescents. | 24160219 |
| Chronicity, Inflammation | Altered Intercellular Communication | Conicity index as a contributor marker of inflammation in haemodialysis patients. | 24160234 |
| HD Term Type, Inflammation | Altered Intercellular Communication | Abdominal fat mass is an important risk factor of inflammation in the general population as it is in haemodialysis (HD) patients. | 24160234 |
| HD Term Type, Inflammation | Altered Intercellular Communication | Results support the hypothesis that inflammation in HD patients has pleiotropic effects depending on abdominal body adiposity. | 24160234 |
| Acute inflammation | Altered Intercellular Communication | Efficacy and safety of intracameral triamcinolone acetonide to control postoperative inflammation after phacotrabeculectomy. | 24160382 |
| Inflammation, Inflammatory disorder | Altered Intercellular Communication | The aim of the present study was to test the hypothesis that inflammation affects the expression of Fe-related proteins in the duodenum and monocytes of patients with chronic inflammatory disorders, thus contributing to dysregulated Fe homeostasis. | 24160450 |
| methyldopa, Inflammation | Altered Intercellular Communication | Apoptosis and inflammation play important roles in AMD pathogenesis. | 24160756 |
| Scleral Diseases, Orbital Pseudotumor | Altered Intercellular Communication | Immunoglobulin G4-related sclerosing disease with orbital inflammation in a 12-year-old girl. | 24160980 |
| Scleral Diseases, Orbital Pseudotumor | Altered Intercellular Communication | Immunoglobulin G4-related sclerosing disease is a rare but potentially debilitating cause of orbital inflammation, with a predilection for older males. | 24160980 |
| Inflammation | Altered Intercellular Communication | N-terminal pro-brain natriuretic peptide levels were found to be a valuable determinant in indicating cardiac inflammation and haemodynamics. | 24161016 |
| Inflammation | Altered Intercellular Communication | Studies have indicated that human CAVD tissues are infiltrated by lipids and that inflammation may play a role in the pathobiology. | 24161325 |
| Inflammation, Fibrosis Assessment, Fatty degeneration | Altered Intercellular Communication | Here, MnSOD mRNA negatively correlates with steatosis grade but not with extent of fibrosis or inflammation. | 24161595 |
| Inflammation, EIU | Altered Intercellular Communication | The LPLA2 activity in rat AH was significantly increased by EIU induction, and was correlated to the extent of inflammation in the AC. | 24161624 |
| Inflammation | Altered Intercellular Communication | These results demonstrate that the LPLA2 activity in the AH is augmented with the inflammation in the AC and suggest that the LPLA2 in the AH participates in the inflammation process in the AC. | 24161624 |
| myocardial injury | Altered Intercellular Communication | Loss of ACE2 exacerbates AngII-mediated inflammation, myocardial injury and dysfunction in ACE2-deficient hearts via activation of the CTGF-FKN-ERK and MMP signaling. | 24161906 |
| Inflammation, Hypertension, CTCAE | Altered Intercellular Communication | Hypertension impairs left ventricular (LV) diastolic and systolic function, which might be aggravated by inflammation or neurohumoral activation. | 24162729 |
| Inflammation, Hypersensitivity | Altered Intercellular Communication | CoCr-EES showed a lower inflammation score (with no hypersensitivity) and less fibrin deposition versus SES and PES. | 24163064 |
| Inflammation, Thrombosis | Altered Intercellular Communication | CoCr-EES demonstrated greater strut coverage with less inflammation, less fibrin deposition, and less late and very late stent thrombosis compared with SES and PES in human autopsy analysis. | 24163064 |
| Hepatic Metabolism, Fibrosis Assessment, Acute inflammation | Altered Intercellular Communication | We hypothesize that presence of fibrosis, reduction of active inflammation, and decreased hepatic metabolism and function are potential causes of the lower FDG uptake in cirrhotic livers. | 24163174 |
| Inflammation, Peritonitis | Altered Intercellular Communication | As neutrophils treated with DAPKi also showed reduced recruitment to the site of inflammation in a mouse peritonitis model, DAPK2 may be a novel target for anti-inflammatory therapies. | 24163421 |
| Inflammatory, Inflammation, Inflammatory disorder | Altered Intercellular Communication | Recently, the increased knowledge in the field of auto inflammation highlighted shared immune mechanisms in the pathogenesis of both classical monogenetic and multifactorial auto inflammatory diseases and a broad spectrum of chronic age-related inflammatory pathologies. | 24164192 |
| Inflammation, Inflammatory disorder | Altered Intercellular Communication | In the light of these considerations, we propose an update of auto inflammatory diseases and a new interpretation of auto inflammation with both theoretical and clinical implications. | 24164192 |
| Communicable Diseases, Inflammation | Altered Intercellular Communication | Surgical site inflammation and infection were graded based on degree of inflammation, discharge, wound culture, and blood culture. | 24164587 |
| Communicable Diseases, Inflammation | Altered Intercellular Communication | Fifty-eight patients developed surgical site inflammation and infection. | 24164587 |
| Inflammation, Diabetes Mellitus | Altered Intercellular Communication | Multivariate logistic regression analysis showed that risk factors for significant CAD included age, diabetes, smoking and inflammation, whereas high serum Klotho values were associated with a lower risk for CAD. | 24165855 |
| Inflammation, Obesity | Altered Intercellular Communication | A meal replacement may be an effective strategy in the management of obesity to increase antioxidant intake, attenuating oxidative stress and inflammation. | 24166510 |
| Gastrointestinal inflammation | Altered Intercellular Communication | Patients with intestinal inflammation (n=20) had higher BMI SDS than those without, p=0.007. | 24167070 |
| Inflammation, Diabetes Mellitus, Non-Insulin-Dependent | Altered Intercellular Communication | Multivariate path analysis of serum 25-hydroxyvitamin D concentration, inflammation, and risk of type 2 diabetes mellitus. | 24167365 |
| Degenerative polyarthritis, Inflammation | Altered Intercellular Communication | Inflammation plays a crucial role in the development and progression of osteoarthritis (OA). | 24167367 |
| Sinusitis | Altered Intercellular Communication | Chronic sinusitis can be caused by many different diseases that share chronic inflammation of the sinuses as a common symptom. | 24167940 |
| Inflammation | Altered Intercellular Communication | Few studies have examined the association of nonexercise physical activity with markers of inflammation and oxidative stress. | 24168102 |
| Inflammation | Altered Intercellular Communication | Daily nonexercise physical activity is associated with lower levels of systemic inflammation. | 24168102 |
| Inflammation | Altered Intercellular Communication | There was no occurrence of systemic reaction, local inflammation or exudation.Wounds were healed at Phase I. | 24169289 |
| Inflammation, Carcinoma | Altered Intercellular Communication | Inflammation as a validated prognostic determinant in carcinoma of unknown primary site. | 24169348 |
| Malignant Neoplasms | Altered Intercellular Communication | Inflammation-based prognostic systems are stage-independent prognostic predictors in various malignancies. | 24169348 |
| Necrotizing granulomatous inflammation, Tuberculosis | Altered Intercellular Communication | Tuberculosis was diagnosed by presence of acid fast bacilli in sputum smears, positive culture for Mycobacterium tuberculosis or demonstration of chronic caseating granulomatous inflammation in tissue specimens. | 24169384 |
| Inflammation | Altered Intercellular Communication | The histology showed a granulomatous inflammation of the epiglottis. | 24169483 |
| Tumor necrosis, Inflammation, Hypertension, CTCAE | Altered Intercellular Communication | Disturbed tumor necrosis factor system is linked with lower eGFR and chronic inflammation in hypertension. | 24170558 |
| Inflammation, Haiti | Altered Intercellular Communication | HT showed higher rates of insulin resistance and enhanced chronic inflammation compared with NT. | 24170558 |
| Renal Insufficiency, Inflammation, Haiti | Altered Intercellular Communication | Regression analysis indicated that the TNF-related parameters were closely linked with mild renal dysfunction both in NT and HT, and moderately related to chronic inflammation only in HT. | 24170558 |
| Inflammation, Haiti | Altered Intercellular Communication | These results suggest that the disturbed TNF system is closely linked with chronic inflammation rather than with insulin resistance in HT. | 24170558 |
| Inflammation, Metabolic Syndrome X, PPP1R12A gene, Depression, CTCAE, Somatic, Cardiovascular system | Altered Intercellular Communication | To investigate the association between depression, metabolic syndrome (MBS), somatic, particularly cardiovascular comorbidity, and low-grade chronic inflammation assessed using C-reactive protein (CRP). | 24170724 |
| Inflammation, Metabolic Syndrome X, Dirty Bombs, Depression, CTCAE, Comorbidity | Altered Intercellular Communication | We found some intriguing links between stress, depression, metabolic syndrome, and low grade inflammation, which may be relevant for the prevalence of somatic comorbidity in patients with RDD, but further studies are needed to confirm our results. | 24170724 |
| Hypercalcemia, Lupus Erythematosus, Systemic | Altered Intercellular Communication | On follow-up, the faster increase in FGF23 than in parathyroid hormone suggested that FGF23 might be involved in the pathogenesis of hypercalcaemia in SLE. | 24171337 |
| Laryngitis, Hoarseness | Altered Intercellular Communication | Objective detection of esophagopharyngeal reflux in patients with hoarseness and endoscopic signs of laryngeal inflammation. | 24172180 |
| Inflammation, Fibrosis Assessment, Acute respiratory failure | Altered Intercellular Communication | The activins A and B, members of the Transforming Growth Factor b family of proteins, and their binding protein, follistatin, have recently been shown to be important regulators of inflammation and fibrosis but no substantial data are available concerning their roles in ARF. | 24172607 |
| Inflammation, Neoplasms | Altered Intercellular Communication | Inflammation is a critical component of tumor progression. | 24175807 |
| Communicable Diseases, Inflammation, Irritation - emotion, Malignant Neoplasms | Altered Intercellular Communication | Many cancers arise from sites of infection, chronic irritation, and inflammation. | 24175807 |
| Inflammation, Liver carcinoma, FAM126A gene | Altered Intercellular Communication | Increasing evidence correlates the presence of systemic inflammation with poor survival in patients with hepatocellular carcinoma (HCC). | 24175853 |
| Inflammation, Cardiovascular finding | Altered Intercellular Communication | Perioperative cardiovascular system failure in South Asians undergoing cardiopulmonary bypass is associated with prolonged inflammation and increased Toll-like receptor signaling in inflammatory monocytes. | 24176205 |
| Orbital Pseudotumor | Altered Intercellular Communication | Trochleitis is an unusual form of orbital inflammation localized to the superior oblique tendon and trochlea complex. | 24176730 |
| Rheumatoid Arthritis, Juvenile rheumatoid arthritis, Lupus Erythematosus | Altered Intercellular Communication | It has been associated with a number of systemic inflammatory conditions including systemic lupus erythematous, rheumatoid arthritis, and juvenile idiopathic arthritis. | 24176730 |
| Degenerative polyarthritis, Inflammation, Metabolic Diseases | Altered Intercellular Communication | Chronic low-grade inflammation is a feature shared by osteoarthritis and metabolic disorders and may contribute to the genesis of both. | 24176735 |
| MS gene, Inflammation, Demyelination, Neuronal loss in central nervous system | Altered Intercellular Communication | A substantial proportion of cases with secondary progressive multiple sclerosis have extensive inflammation in the leptomeninges that is associated with increased subpial demyelination, neuronal loss and an exacerbated disease course. | 24176976 |
| Musculoskeletal, Shoulder Injuries | Altered Intercellular Communication | F-FDG-PET/CT may be useful for the screening of musculoskeletal inflammation and injury of the shoulder region. | 24177044 |
| Inflammation, Chronic sinusitis, Craniosynostosis | Altered Intercellular Communication | Chronic rhinosinusitis (CRS) is the persistent inflammation of the sinus and nasal passages lasting over 3 months. | 24177790 |
| Malabsorption Syndrome, Gastrointestinal Diseases, Gastrointestinal inflammation | Altered Intercellular Communication | Cystic fibrosis gastrointestinal disease includes nutrient malabsorption and intestinal inflammation. | 24178246 |
| Malabsorption Syndrome, Fibrosis Assessment, Inflammation, Gastrointestinal dysfunction | Altered Intercellular Communication | We show that the abundances of Escherichia coli in fecal microbiota were significantly higher in young children with cystic fibrosis than in controls and correlated with fecal measures of nutrient malabsorption and inflammation, suggesting that E. coli could contribute to cystic fibrosis gastrointestinal dysfunction. | 24178246 |
| Overweight, atherosclerotic | Altered Intercellular Communication | We conducted a prospective study to evaluate the impact of overweight on atherosclerotic events (AE) in dialysis patients with special respect to the malnutrition/inflammation complex syndrome (MICS). | 24179012 |
| atherosclerotic | Altered Intercellular Communication | Furthermore, it appears to reflect aspects of atherosclerotic inflammation distinct from hsCRP concentration and may offer incremental information regarding cardiovascular risk. | 24179183 |
| Inflammation | Altered Intercellular Communication | In particular, the signal for serum IL-18 located on chromosome two is novel and potentially important in inflammasome triggered chronic activation of inflammation in older adults. | 24182552 |
| Inflammation, Diabetes Mellitus, Bipolar Disorder | Altered Intercellular Communication | Diabetes, depressive symptoms, and inflammation in older adults: results from the Health, Aging, and Body Composition Study. | 24182629 |
| Inflammation, Bipolar Disorder | Altered Intercellular Communication | This study examined the association between inflammation and both T2DM and elevated depressive symptoms. | 24182629 |
| Inflammation, Bipolar Disorder | Altered Intercellular Communication | These findings provide evidence that inflammation is associated with T2DM and elevated depressive symptoms. | 24182629 |
| Inflammation | Altered Intercellular Communication | Systemic low graded inflammation has been identified as a possible biological pathway in late-life depression. | 24182633 |
| Inflammation, Rheumatoid Arthritis | Altered Intercellular Communication | EBV-encoded small RNA1 and nonresolving inflammation in rheumatoid arthritis. | 24183354 |
| Inflammation, Numerous, Refractory anemias, Autoimmune Diseases, Rheumatoid Arthritis | Altered Intercellular Communication | Rheumatoid arthritis (RA) is a chronic autoimmune disease characterized by perpetuated inflammation in multiple joints. | 24183354 |
| Refractory anemias, Inflammation | Altered Intercellular Communication | To date, there is no cure for RA, and the causal factor for non-resolving inflammation in RA remains unclear. | 24183354 |
| Inflammation | Altered Intercellular Communication | In this study, we initially observed expression of Epstein-Barr virus-encoded small RNA1 (EBER1) in the synovial tissue of all five patients who showed nonresolving RA inflammation. | 24183354 |
| Degenerative polyarthritis | Altered Intercellular Communication | To confirm this finding, we conducted a second study on synovial tissue samples taken from 23 patients with nonresolving RA inflammation and 13 patients with OA. | 24183354 |
| Refractory anemias, Inflammation, Degenerative polyarthritis | Altered Intercellular Communication | All synovial samples from patients with nonresolving inflammation of RA showed positive expression of EBER1 (23/23, 100%), whereas none of the synovial samples from patients with OA showed expression of EBER1 (0/13, 0%; p < 0.001, by Fisher's exact test). | 24183354 |
| Inflammation | Altered Intercellular Communication | Taken together, these data strongly suggest that nonresolving RA inflammation is strongly related to the presence of EBER1, which might be, at least partially, responsible for synovial fibroblast interleukin-6 production. | 24183354 |
| Inflammation, Hepatitis B | Altered Intercellular Communication | Hepatitis B virus (HBV) can result in asymptomatic carrier (AsC) state or chronic inflammation of liver, which depends on the host immunity. | 24183880 |
| Inflammation, physiopathological, Obesity | Altered Intercellular Communication | the low degree of inflammation in obesity contributes to systemic metabolic dysfunction. | 24184299 |
| Aneurysm, Inflammation | Altered Intercellular Communication | Extensive work-up revealed a 3-cm SMA aneurysm (SMAA) with surrounding inflammation. | 24184459 |
| Arthralgia, Pain Distress Question, Inflammation | Altered Intercellular Communication | Pain diminished after 3 months, while associations between painful joints and inflammation seem to increase, emphasizing the multifactorial aetiology of pain. | 24185107 |
| Inflammation, Primary Biliary Cholangitis | Altered Intercellular Communication | Chemokine-chemokine receptor CCL2-CCR2 and CX3CL1-CX3CR1 axis may play a role in the aggravated inflammation in primary biliary cirrhosis. | 24185682 |
| Inflammation, Bile duct structure, Primary Biliary Cholangitis | Altered Intercellular Communication | CCL2 and CX3CL1 produced by senescent BECs may promote infiltration of corresponding CCR2 and CX3CR1-expressing cells and further aggravate inflammation in bile duct lesion in PBC. | 24185682 |
| Airway structure, ARCN1 gene, Progranulins | Altered Intercellular Communication | Progranulin is a substrate for neutrophil-elastase and proteinase-3 in the airway and its concentration correlates with mediators of airway inflammation in COPD. | 24186875 |
| ARCN1 gene, Inflammation, Chronic Obstructive Airway Disease, GRN wt Allele | Altered Intercellular Communication | Because dysregulated neutrophilic inflammation is implicated in the pathophysiology of chronic obstructive pulmonary disease (COPD), the possible influence of PGRN and digestion products may be of relevance to understanding and treating inflammation in the disease. | 24186875 |
| Airway structure, ARCN1 gene, Colonization, GRN wt Allele | Altered Intercellular Communication | The concentration of PGRN relates negatively to the amplified airway inflammation associated with bacterial colonization in clinically stable COPD. | 24186875 |
| Inflammation, destruction joint, Synovial Fluid | Altered Intercellular Communication | Our data confirm the evidence that synovial PD activity more accurately reflects active synovial inflammation (which actually causes joint destruction) than do conventional measures in patients treated with MTX. | 24187096 |
| Refractory anemias, Pain Distress Question, Inflammation | Altered Intercellular Communication | ChWP is a common feature in RA, more associated with high values for variables related to pain such as the DAS28 and HAQ than to indicators of ongoing inflammation such as swollen joint count, ESR, and CRP. | 24187108 |
| Chronic inflammation | Altered Intercellular Communication | Vitamin D receptor mRNA expression levels were significantly upregulated in H. pylori-infected patients and positively correlated with chronic inflammation scores. | 24188043 |
| Inflammation | Altered Intercellular Communication | Our results suggest a role of the oral microbiota in the development of inflammation in atherogenesis, particularly of A. actinomycetemcomitans. | 24188425 |
| Inflammation, Chronic disease | Altered Intercellular Communication | The relationship between high-sensitivity CRP and polyclonal free light chains as markers of inflammation in chronic disease. | 24188493 |
| Fibrosis Assessment, Hepatic inflammation, Fatty degeneration | Altered Intercellular Communication | A univariate analysis showed that the body mass index, platelet count, levels of albumin, aspartate aminotransferase, alanine aminotransferase and g-glutamyl transpeptidase, glucose metabolism, hepatic inflammation, fibrosis and steatosis were associated with elevated AFP levels. | 24190142 |
| Proteinuria, Diarrhea, Bothered by Vomiting, Nausea, Treatment-Emergent Adverse Event, Hypertension, CTCAE, Inflammatory disease of mucous membrane, Fatigue | Altered Intercellular Communication | The most common treatment-related treatment-emergent adverse events (all dosing cohorts) were fatigue 60 % (Grade >=3: 10 %), mucosal inflammation 50 %, proteinuria (Grade >=3: 15 %), diarrhea (Grade >=3: 10 %), vomiting (Grade >=3: 5 %), hypertension, and nausea, each 40 %. | 24190702 |
| Tissue damage, Inflammation | Altered Intercellular Communication | Crucially, aberrant migration may increase "bystander" tissue damage and heighten inflammation as a result of excess proteinase release during inaccurate chemotaxis, as well as reducing pathogen clearance. | 24191150 |
| Inflammation | Altered Intercellular Communication | We show evidence of increased neutrophil proteinase activity in older adults, namely, raised levels of neutrophil proteinase substrate-derived peptides and evidence of primary granule release, associated with increased systemic inflammation. | 24191150 |
| Inflammation, Infection | Altered Intercellular Communication | Targeting PI3K signaling may therefore offer a new strategy in improving neutrophil functions during infections and reduce inappropriate inflammation in older patients. | 24191150 |
| Inflammatory disorder | Altered Intercellular Communication | sIL-1R2 has potential to be a chemopreventive and/or immunotherapeutic agent in inflammation-related diseases. | 24192010 |
| Inflammation, Coronary Artery Disease | Altered Intercellular Communication | High oxidative stress and chronic inflammation can contribute to the pathogenesis of coronary artery disease (CAD). | 24192015 |
| Celiac Disease, Gastrointestinal inflammation | Altered Intercellular Communication | Coeliac disease (CD) is a common T cell-mediated disease diagnosed by the presence of gluten-dependent intestinal inflammation and serology. | 24192268 |
| Inflammation, Pain Distress Question | Altered Intercellular Communication | Previously, we found that the inflammatory-related transcripts were elevated in growth plate and articular cartilages, indicating that inflammation plays an important role in the chondrocyte disease pathology and may contribute to the overall pain sequelae. | 24194321 |
| Inflammation | Altered Intercellular Communication | Important and novel findings were an increase in inflammatory proteins generally starting at P21 and that exercise exacerbates inflammation. | 24194321 |
| Inflammation, Tissue injury | Altered Intercellular Communication | In contrast, HIF-2a-deficient murine inflammatory neutrophils displayed increased sensitivity to nitrosative stress induced apoptosis ex vivo and increased neutrophil apoptosis in vivo, resulting in a reduction in neutrophilic inflammation and reduced tissue injury. | 24196071 |
| Inflammation | Altered Intercellular Communication | Expression of HIF-2a was temporally dissociated from HIF-1a in vivo and predominated in the resolution phase of inflammation. | 24196071 |
| Inflammation, Chronic inflammatory disorder | Altered Intercellular Communication | These data support a critical and selective role for HIF-2a in persistence of neutrophilic inflammation and provide a platform to dissect the therapeutic utility of targeting HIF-2a in chronic inflammatory diseases. | 24196071 |
| Inflammation | Altered Intercellular Communication | Whereas FDG PET/CT imaging has been widely used in periprosthetic infection, it cannot discriminate aseptic from septic inflammation. | 24196917 |
| Inflammation | Altered Intercellular Communication | It is therefore possible that senescent cells can differentially induce inflammation in the surrounding tissues, depending on the cause of senescence. | 24198727 |
| Inflammation, Disorder of eye, Neoplasms, Retinal Detachment, Communicable Diseases, Abnormality of the vasculature | Altered Intercellular Communication | Exudative retinal detachment as subretinal fluid accumulation occurs due to chorioretinal eye disease (inflammation, infection, tumor, vascular abnormalities) and in systemic diseases too. | 24199273 |
| Depression, CTCAE, Brain hemorrhage | Altered Intercellular Communication | To explore the relation between plasma neurotransmitters (Glutamic acid, GAA; g-aminobutyric acid, GABA; 5-hydroxytryptamine, 5-HT; and noradrenaline, NE) and depression in acute hemorrhagic stroke. | 24199885 |
| Inflammation, Injury of kidney | Altered Intercellular Communication | These positive results with inflammation biomarkers and lifespan studies suggest that the BPP can protect mice against LPS/GalN-induced liver, lung, and kidney injuries and inflammation by blocking oxidative stress and TNF-a production, thus increasing the survival of the toxic shock-induced mice. | 24200110 |
| Inflammation, Aneurysm, Infected | Altered Intercellular Communication | Infected aortic aneurysms are diagnosed on the basis of a positive bacterial blood culture, clinical evidence of inflammation, and morphologic findings on computed tomography (CT). | 24200128 |
| Inflammation, "Alzheimers Disease | Altered Intercellular Communication | Low Level Laser Therapy has already been demonstrated to mitigate amyloid-b peptide induced oxidative stress and inflammation, a key driver of Alzheimer's disease. | 24200521 |
| Inflammation | Altered Intercellular Communication | Lipoprotein properties were severely impaired in the AF group with increased extent of oxidation and inflammation. | 24201066 |
| Inflammation, Villous, Gastrointestinal symptom | Altered Intercellular Communication | Daily intake and long-term consumption of oats did not result in small-bowel mucosal villous damage, inflammation, or gastrointestinal symptoms. | 24201240 |
| Inflammation | Altered Intercellular Communication | Inflammaging is a phenomenon triggered by the conjunction of chronic repetitive and subclinical inflammation from external aggressors and internal inflammatory mechanisms due to the progressive degradation of systems such as the mitochondrial function. | 24202618 |
| Inflammation | Altered Intercellular Communication | Inflammaging is a phenomenon triggered by the conjunction of chronic repetitive and subclinical inflammation from external aggressors and internal inflammatory mechanisms due to the progressive degradation of systems such as the mitochondrial function. | 24202618 |
| methyldopa, Inflammation | Altered Intercellular Communication | Remarkable correlations have been documented between common or rare immunological/inflammatory gene polymorphisms and AMD, unequivocally indicating the involvement of inflammation and immune-mediated processes (complement activation) in the pathogenesis of this disease. | 24202618 |
| Inflammation, Specimen Type - Fistula | Altered Intercellular Communication | Chronic inflammation process will induce longer adhesion area between artery and ureter, which results in unusual fistula site and rigid iliac arteries. | 24203347 |
| Inflammation, Cardiac Arrhythmia, Cardiovascular Diseases | Altered Intercellular Communication | Inflammation has recently emerged in the pathogenesis of several cardiovascular disorders, including arrhythmias. | 24203349 |
| glycation, Inflammation | Altered Intercellular Communication | The accumulation of advanced glycation end products (AGEs) has been reported to be a major contributor to chronic systemic inflammation. | 24206165 |
| Inflammation, Metabolic Syndrome X | Altered Intercellular Communication | We aimed to evaluate the presence of metabolic syndrome and to assess the insulin resistance associated with chronic inflammation in patients with PsA. | 24206172 |
| Inflammation | Altered Intercellular Communication | Evidence of increased inflammation was demonstrated by an increase in CRP and ESR (P <= 0.05, THR and TKR). | 24206644 |
| Inflammation | Altered Intercellular Communication | Elevated troponin I levels but not low grade chronic inflammation is associated with cardiac-specific mortality in stable hemodialysis patients. | 24206774 |
| Inflammation, Coronary Arteriosclerosis, myocardial injury | Altered Intercellular Communication | The mechanism for this risk is likely independent of inflammation, but may reflect chronic subclinical myocardial injury or unmask those with subclinical atherosclerotic heart disease. | 24206774 |
| Inflammation, Metabolic Syndrome X | Altered Intercellular Communication | The metabolic syndrome is featured by enhanced low-grade systemic inflammation and oxidative stress. | 24209691 |
| Inflammation, Complete atrioventricular block | Altered Intercellular Communication | We investigated whether serum M30-antigen levels might help to characterize the various phases of CHB and predict the state of significant inflammation in patients with CHB. | 24210327 |
| Inflammation, Complete atrioventricular block | Altered Intercellular Communication | Serum M30 levels are associated with the presence of significant inflammation, especially in patients with normal or minimally elevated ALT in CHB patients. | 24210327 |
| Inflammation, Oculomotor Nerve Paralysis, Neoplasms, Traumatic injury | Altered Intercellular Communication | Common causes for acquired isolated oculomotor nerve palsy in children are trauma, inflammation, and neoplasia. | 24210342 |
| Inflammation, Acute Coronary Syndrome, GDC AJCC Clinical Stage Terminology | Altered Intercellular Communication | Systemic inflammation at the development of an acute coronary syndrome (ACS) might alter the high-density lipoprotein (HDL) components and function. | 24210679 |
| Inflammation | Altered Intercellular Communication | The ACS1 group showed a marked increase in high-sensitivity C-reactive protein and serum amyloid A, reflecting systemic inflammation. | 24210679 |
| Inflammation, Vasculitis, CTCAE | Altered Intercellular Communication | The typical inflammation signs of the vascular wall demonstrated by the gadolinium-enhanced MRI strengthened the hypothesis of CNS vasculitis. | 24211061 |
| Inflammation, Uveitis | Altered Intercellular Communication | Of masquerade syndrome patients, 90% had posterior inflammation, compared with 63% of uveitis patients (P = 0.006). | 24211361 |
| Inflammation, Neoplastic masquerade syndrome | Altered Intercellular Communication | Patients with neoplastic masquerade syndromes were more likely to be older, male, or non-African American and to have posterior segment inflammation and unilateral disease. | 24211361 |
| Inflammation | Altered Intercellular Communication | Objective impairments correlated significantly with self-reported symptoms (p<0.05) as well as levels of the inflammation marker, C-reactive protein (p=0.001). | 24211375 |
| Gastrointestinal inflammation | Altered Intercellular Communication | However, little is known about these cells, their precursors, and their role in intestinal inflammation. | 24212097 |
| Airway structure | Altered Intercellular Communication | A few epidemiologic studies have shown elevations in the fraction of exhaled nitric oxide, a marker of airway inflammation, after exposure to traffic-related pollutants. | 24213146 |
| Airway structure | Altered Intercellular Communication | We examined whether short-term exposures to ozone (O3), oxides of nitrogen (NOx), or particulate matter <10 mm (PM10) were associated with proximal and distal airway inflammation. | 24213146 |
| Airway structure, Inflammation | Altered Intercellular Communication | Exposure to O3 was associated with a marker of distal airway inflammation, while the association was less obvious for inflammation of the proximal airways. | 24213146 |
| Sparganosis, Orbital Pseudotumor | Altered Intercellular Communication | Despite its rarity, ocular sparganosis should be considered as a possible cause of orbital inflammation in patients. | 24215169 |
| Inflammation, Acute Coronary Syndrome, Blood Vessel, GDC AJCC Clinical Stage Terminology | Altered Intercellular Communication | Long pentraxin 3 (PTX3) is a component of the pentraxin superfamily and a potential marker of vascular damage and inflammation, associated with negative outcome in patients with acute coronary syndromes (ACS). | 24215445 |
| Inflammation | Altered Intercellular Communication | Histologically, 24 (89%) of these had little inflammation, and 26 (96%) were negative for H. pylori by immunohistochemistry. | 24215601 |
| Inflammation, Spondylitis, Autoimmune Disorder, CTCAE | Altered Intercellular Communication | Ankylosing spondylitis (AS) is an autoimmune disorder characterized by inflammation of the spine and large joints. | 24215664 |
| Renal Insufficiency | Altered Intercellular Communication | We recently demonstrated involvement of the inflammatory classical NF-kB pathway in inflammation-induced impairments in muscle OXPHEN. | 24215713 |
| ARCN1 gene, Muscle (organ) | Altered Intercellular Communication | We hypothesised that inflammation-induced classical NF-kB activation contributes to loss of muscle OXPHEN in COPD by reducing IKK-a expression. | 24215713 |
| Degenerative polyarthritis, Inflammation | Altered Intercellular Communication | Identification and characterisation of osteoarthritis patients with inflammation derived tissue turnover. | 24216059 |
| Degenerative polyarthritis, Arthritis, Degenerative disorder | Altered Intercellular Communication | Osteoarthritis (OA) is a degenerative disease with a subset of patients experiencing joint inflammation, but C-reactive protein (CRP) has shown limited use in OA as a diagnostic marker. | 24216059 |
| Degenerative polyarthritis, Inflammation | Altered Intercellular Communication | A bigger proportion of patients were elevated in CRPM compared to hsCRP, indicating MMP-derived inflammation as a component of OA. | 24216059 |
| Inflammation, Primary malignant neoplasm, Miller Dieker syndrome | Altered Intercellular Communication | Here we report that myeloid-derived suppressor cells (MDSC), which are classically linked to immunosuppression, inflammation, and cancer, were markedly expanded in the bone marrow of MDS patients and played a pathogenetic role in the development of ineffective hematopoiesis. | 24216507 |
| Neurogenic Inflammation, Traumatic, Ischemic stroke, Edema | Altered Intercellular Communication | SP has been implicated in the development of neurogenic inflammation and subsequent edema development following both traumatic brain injury and ischemic stroke. | 24216617 |
| Inflammation, Calcification of the aorta | Altered Intercellular Communication | Furthermore, FLC k and l levels were positively correlated with inflammation, aortic calcification and the levels of various uremic toxins levels. | 24217396 |
| Inflammation, Chronic Kidney Diseases, Vascular calcification | Altered Intercellular Communication | In conclusion, our results indicate that FLC k and l levels are elevated in CKD patients and are associated with inflammation, vascular calcification and levels of other uremic toxins. | 24217396 |
| Inflammation | Altered Intercellular Communication | Chronic inflammation has been associated with decreased physical function in the elderly and may also influence physical function in HIV-infected individuals. | 24219874 |
| Inflammation, Muscular Dystrophy, Myopathy, Myositis | Altered Intercellular Communication | Muscular dystrophies (MDs) and inflammatory myopathies (IMs) are debilitating skeletal muscle disorders characterized by common pathological events including myodegeneration and inflammation. | 24220031 |
| Excessive tearing, Inflammation, Stenosis Morphology | Altered Intercellular Communication | If the wounds are not managed properly, they can lead to scarring, stenosis, and inflammation, which may lead to symptomatic epiphora. | 24220405 |
| Inflammation, Irritation, Lacrimal Duct Obstruction, Granuloma | Altered Intercellular Communication | No complications related to the Mini-Monoka tube, such as punctual plug migration, eye irritation, inflammation, granuloma formation, or erosion, occurred during the follow-up period.The goal of reconstructing a lacerated canaliculus is accurate approximation of the injured end of the canaliculus to facilitate mucosal healing and to prevent a canalicular obstruction. | 24220405 |
| Inflammation, Breast Carcinoma | Altered Intercellular Communication | Inflammation and immune response may have potential prognostic implications for breast cancer survivors. | 24220913 |
| Inflammation, Breast Carcinoma | Altered Intercellular Communication | Acute inflammation status (CRP >= 10 mg/L) may be an important independent biomarker for long-term survival in breast cancer survivors. | 24220913 |
| Acute inflammation, Breast Carcinoma | Altered Intercellular Communication | Interventions to decrease circulating CRP concentrations in breast cancer survivors with acute inflammation may improve prognosis. | 24220913 |
| Inflammation | Altered Intercellular Communication | Systemic immune defects might reflect severely dysregulated control of chronic inflammation related to disease progression. | 24221190 |
| Inflammation | Altered Intercellular Communication | Disease activity was calculated on the basis of clinical and biochemical indices of inflammation (DAS28, ESR, CRP). | 24221190 |
| Refractory anemias, Inflammation | Altered Intercellular Communication | Although therapy induced clinical improvement in almost all patients, those with advanced RA remained with signs of inflammation. | 24221190 |
| Cessation of life, Inflammation | Altered Intercellular Communication | All three biomarkers of inflammation were associated with an increased risk of macrovascular events and death in analyses adjusted for age, sex, and treatment groups. | 24222348 |
| Refractory anemias, Inflammation, Endothelial dysfunction | Altered Intercellular Communication | Endothelial dysfunction has been detected in RA patients and seems to be reversed by control of inflammation. | 24222719 |
| Autoimmune Diseases, Inflammation | Altered Intercellular Communication | Th17 cells, a recently discovered subset of T helper cells that secrete IL-17A, can affect the inflammation process autoimmune and cancer diseases development. | 24223764 |
| Inflammation, Primary malignant neoplasm | Altered Intercellular Communication | With growing evidence on the role of inflammation in cancer biology, the presence of a systemic inflammatory response has been postulated as having prognostic significance in a wide range of cancer types. | 24223776 |
| Inflammation | Altered Intercellular Communication | Valvular calcification, inflammation, and mortality in dialysis patients. | 24224425 |
| Down Syndrome, Inflammation | Altered Intercellular Communication | A recent study has found that aerobic training reduced inflammation in obese women with Down syndrome. | 24224738 |
| Acute and chronic inflammation | Altered Intercellular Communication | A 3-month detraining period significantly impaired chronic inflammation in obese women with DS. | 24224738 |
| Inflammation, Periodontitis | Altered Intercellular Communication | Chronic periodontitis (CP) is a continuous, reversible source of inflammation with a potential impact on mortality in patients undergoing hemodialysis (HD). | 24224959 |
| Periodontal Infection, Bronchitis | Altered Intercellular Communication | Individuals with periodontal infection showed, approximately, five times more likelihood to have bronchial inflammation than those without such periodontal tissue infection. | 24224961 |
| Periodontitis, Asthma, Bronchitis | Altered Intercellular Communication | The findings demonstrate the influence of periodontitis on severe asthma, given that the frequency of periodontitis is higher in individuals with severe asthma than in those without a diagnosis of bronchial inflammation. | 24224961 |
| Intracranial Germinoma, Failure (biologic function) | Altered Intercellular Communication | [Intracranial germinoma masquerading as a granulomatous inflammation, diagnostic failure after brain biopsy]. | 24225569 |
| Granulomatous inflammation, Pineal germinoma | Altered Intercellular Communication | We concluded that the possibility of germinoma should be considered in case granulomatous inflammation is observed in brain biopsy specimens. | 24225569 |
| Inflammation, Primary malignant neoplasm | Altered Intercellular Communication | And human medical evidence suggests a net aggravation of cancer risk from the sequestration of telomerase, because cells with short telomeres are at high risk of neoplastic transformation, and they also secrete cytokines that exacerbate inflammation globally. | 24228928 |
| Inflammation, Carcinoid Tumor, Parasitic Diseases, Taenia Saginata, Diverticulitis, Endometriosis | Altered Intercellular Communication | In the 88 specimens with unusual pathology, fibrous obliteration was observed in 57 specimens, carcinoid tumor in 11, Encheliophis vermicularis parasite infection in 8, granulatomous inflammation in 6, appendiceal endometriosis in 2, and 1 specimen each showed mucocele, eosinophilic infiltration, Taenia saginata parasite infection, and appendicular diverticulitis. | 24229023 |
| Inflammation, Delayed Hypersensitivity | Altered Intercellular Communication | Delayed-type hypersensitivity is induced by induction of inflammation via IL-1, TNF-a and IL-6. | 24229039 |
| Inflammation, Asthma | Altered Intercellular Communication | Systemic inflammation in asthma plays a significant role in the development of other diseases. | 24229680 |
| Hyperglycemia, Inflammation | Altered Intercellular Communication | These results suggest that high consumption of rice and noodles may contribute to hyperglycaemia through greater insulin resistance and that this relationship is independent of adiposity and systemic inflammation. | 24229726 |
| Arteritis, Diabetes Mellitus | Altered Intercellular Communication | Pioglitazone decreases coronary artery inflammation in impaired glucose tolerance and diabetes mellitus: evaluation by FDG-PET/CT imaging. | 24229770 |
| vascular inflammations | Altered Intercellular Communication | Recent studies have shown that FDG-PET combined with CT is a reliable tool to visualize and quantify vascular inflammation. | 24229770 |
| Demographics Domain, Electrocardiogram: myocardial infarction (finding), Coronary Arteriosclerosis, Arteritis, Diabetes Mellitus, Non-Insulin-Dependent | Altered Intercellular Communication | Although pioglitazone significantly prevented the progression of coronary atherosclerosis and reduced the recurrence of myocardial infarction in patients with type 2 diabetes mellitus (DM), it remains unclear whether pioglitazone could attenuate coronary artery inflammation. | 24229770 |
| Inflammation | Altered Intercellular Communication | Our study indicated that pioglitazone attenuated left main trunk inflammation in patients with impaired glucose tolerance or DM in a glucose-lowering independent manner, suggesting that pioglitazone may protect against cardiac events in patients with impaired glucose tolerance or DM by suppressing coronary inflammation. | 24229770 |
| Inflammation | Altered Intercellular Communication | Nuclear factor-kB (NF-kB) regulates cellular responses to inflammation and aging, and alterations in NF-kB signaling underlie the pathogenesis of multiple human diseases. | 24231355 |
| vascular inflammations | Altered Intercellular Communication | HDF decreases uraemic toxins, vascular inflammation, and is associated with subsequent improvement in eNOS functionality. | 24235073 |
| Chronic Kidney Diseases | Altered Intercellular Communication | The inflammation-lipocalin 2 axis may contribute to the development of chronic kidney disease. | 24235082 |
| Inflammation, Chronic Kidney Diseases, Coronary heart disease | Altered Intercellular Communication | Chronic kidney disease (CKD) is an important risk factor for coronary heart disease, and previous studies indicated the involvement of low-grade inflammation in the pathogenesis of CKD. | 24235082 |
| Inflammation, Renal function, Chronic Kidney Diseases | Altered Intercellular Communication | Since an activated TNF system, as demonstrated by elevated sTNF-R2, and elevated uric acid were recently implicated in an elevated CKD risk, we conclude that inflammation could play an important role in the pathogenesis of CKD, and that lipocalin 2 is a potential universal marker for impaired kidney function. | 24235082 |
| Inflammation, Fibrosis Assessment | Altered Intercellular Communication | Reduced nasal nitric oxide production in cystic fibrosis patients with elevated systemic inflammation markers. | 24236100 |
| Inflammation | Altered Intercellular Communication | Interventions aimed at reducing chronic inflammation and immune activation in aging, HIV-infected patients may improve their response to vaccines. | 24236161 |
| Keratoconjunctivitis, Vernal, Inflammation, Chronic disease | Altered Intercellular Communication | Vernal keratoconjunctivitis (VKC) is a chronic disease affecting conjunctiva even though the immunopathogenetic mechanisms underlying this inflammation are unclear. | 24236762 |
| Inflammation | Altered Intercellular Communication | Our study gives a support to the definition of VKC as a systemic inflammation in which HMGB1 and its soluble receptors could play a role. | 24236762 |
| Inflammation, Hyperhomocysteinemia | Altered Intercellular Communication | Patients with hyperhomocysteinemia have increased risk for cardiovascular events that potentially involve enhanced inflammation. | 24236948 |
| Exfoliative cheilitis | Altered Intercellular Communication | Exfoliative cheilitis (EC) is a rare inflammatory condition affecting the vermilion of the lips and characterized by production of a thick keratin scale. | 24237731 |
| Inflammation, Asthma, MS4A2 wt Allele | Altered Intercellular Communication | The fraction of exhaled nitric oxide (FeNO) has been suggested as a non-invasive marker of eosinophilic inflammation in asthma, but lately rather as a biomarker of atopy than of asthma itself. | 24237793 |
| Inflammation, Asthma, Bronchiolitis | Altered Intercellular Communication | Asthma after bronchiolitis is common up to early adolescence, but the inflammation and pathophysiology may differ from other phenotypes of childhood asthma. | 24237793 |
| Inflammation, Exacerbation | Altered Intercellular Communication | The mechanism by which exacerbations occur remains undefined, however it is likely to be due to virus-induced inflammation. | 24237854 |
| Inflammation, Periapical Diseases | Altered Intercellular Communication | MicroRNAs (miRNAs) have been shown to play an important role in the regulation of inflammation and the immune response; however, their role in the pathogenesis of endodontic periapical disease has not been explored. | 24238436 |
| Cataract, Intraocular inflammation, Uveitis | Altered Intercellular Communication | To compare the incidence of long-term complications after cataract surgery with primary anterior chamber intraocular lens (AC IOL) implantation in uveitic patients and patients without a history of intraocular inflammation (control group). | 24238942 |
| Inflammation | Altered Intercellular Communication | A total of 41 cases was reviewed: periarterial inflammation was shown in 10.3% of patients; 92.9% had clear intima-media plane; and 85.4% had a good outcome. | 24239104 |
| Granulomatous inflammation, Tularemia, Necrosis | Altered Intercellular Communication | In particular, if granulomatous inflammation with necrosis is seen histopathologically, tularemia should be excluded before making the diagnosis of TCL. | 24239221 |
| Inflammation, neuroborreliosis, niobium | Altered Intercellular Communication | Knowledge of the role of chemokines in the inflammation during neuroborreliosis (NB) is limited. | 24239846 |
| Inflammation, Infectious Lung Disorder | Altered Intercellular Communication | Volatile organic compounds (VOCs) in breath may serve as biomarkers of pulmonary infection or inflammation. | 24239875 |
| acute diverticulitis, Diverticular Diseases, Colitis | Altered Intercellular Communication | Patients with symptomatic uncomplicated diverticular disease represent a spectrum of patients who report recurrent abdominal symptoms, however are lacking substantial colonic inflammation in contrast to patients with acute diverticulitis. | 24240607 |
| Gastrointestinal inflammation, acute diverticulitis | Altered Intercellular Communication | Patients with acute diverticulitis and symptoms suggestive of more severe intestinal inflammation were excluded. | 24240607 |
| Nerve Degeneration | Altered Intercellular Communication | Pro-inflammatory S100A9 protein is increasingly recognized as an important contributor to inflammation-related neurodegeneration. | 24240735 |
| Vasculitis | Altered Intercellular Communication | We reviewed medical records of 9 consecutive patients with noninfectious ocular or orbital inflammation treated with RTX. | 24241484 |
| Inflammation | Altered Intercellular Communication | Low-grade systemic inflammation induced by smoking may represent the link between these 2 conditions. | 24244639 |
| ARCN1 gene, Inflammation | Altered Intercellular Communication | Only smokers with COPD seem to have evidence of systemic inflammation. | 24244639 |
| Inflammation, Malnutrition, Carcinoma of lung | Altered Intercellular Communication | RDW is associated with several factors that reflect inflammation and malnutrition in lung cancer patients. | 24244659 |
| Inflammation | Altered Intercellular Communication | Low-grade systemic inflammation was suggested to participate to the decline of physiological functions and increased vulnerability encountered in older patients. | 24244750 |
| Inflammation, Cardiovascular Diseases | Altered Intercellular Communication | Association between low-grade inflammation and geriatric conditions could be linked to underlying cardiovascular diseases. | 24244750 |
| Inflammation, Benign prostatic hypertrophy, Adenocarcinoma of prostate | Altered Intercellular Communication | In the study group, patients with prostatic hyperplasia or inflammation on the prostate biopsy had a significantly better result than in patients with prostatic adenocarcinoma, typically in the changes of Qmax and voided volume (p = 0.012 and p = 0.005, respectively). | 24246211 |
| Adenocarcinoma, Inflammation, Benign prostatic hypertrophy | Altered Intercellular Communication | The changes in Qmax and voided volume after combination treatment were significantly greater in patients with prostatic hyperplasia or inflammation than adenocarcinoma. | 24246211 |
| prostatitis | Altered Intercellular Communication | Lower urinary tract symptom improvement after radical prostatectomy correlates with degree of prostatic inflammation. | 24246320 |
| prostatitis | Altered Intercellular Communication | To determine if prostatic inflammation at the time of radical prostatectomy (RP) was associated with the International Prostate Symptom Score (IPSS). | 24246320 |
| Inflammation | Altered Intercellular Communication | We reviewed pathology slides of those who had a change of 4 points or greater, as measured by the IPSS and correlated inflammation with change in IPSS. | 24246320 |
| Inflammation | Altered Intercellular Communication | Multivariate linear regression analyses were performed to determine the association of IPSS with degree of inflammation based on the number of inflammatory cells. | 24246320 |
| Inflammation | Altered Intercellular Communication | On univariate analysis, the average improvement in IPSS in patients with severe inflammation was (r = -6.02, 95% confidence interval [CI] -11.0 to -1.1, P = .018) after RP. | 24246320 |
| prostatitis | Altered Intercellular Communication | On multivariate analysis, adjusting for age, body mass index (BMI), year of surgery, history of prostatitis, Gleason score, prostate-specific antigen (PSA), prostate weight, and nerve sparing status, only patients with severe prostatic inflammation had significant improvement in their IPSS (r = -5.93, 95% CI -10.81 to -1.04, P = .004). | 24246320 |
| prostatitis | Altered Intercellular Communication | Prostatic inflammation measured in prostatectomy specimens is associated with worse baseline IPSS than matched cohorts. | 24246320 |
| Inflammation | Altered Intercellular Communication | Specifically, severe inflammation is an independent predictor of IPSS improvement at 1 year after RP. | 24246320 |
| Inflammation, Metabolic Syndrome X, ETV3 wt Allele, Diabetes Mellitus, Coronary heart disease, Choline Dehydrogenase, Mitochondrial | Altered Intercellular Communication | Given that serum phospholipids (PL) may serve as inflammation mediators, we studied whether they predicted metabolic syndrome (MetS), type-2 diabetes or coronary heart disease (CHD) risk in people prone to enhanced low-grade inflammation. | 24246837 |
| Inflammation | Altered Intercellular Communication | This suggests that chronic inflammation and immune system over-activity may underlie the aging process of the human brain, and that potential anti-inflammatory treatments targeting those genes may slow down this process and alleviate its symptoms. | 24247109 |
| Inflammation, Chronic Kidney Diseases, Obesity | Altered Intercellular Communication | We hypothesized that the association of central obesity with CKD is modified by the presence of inflammation. | 24247217 |
| Inflammation, Obesity | Altered Intercellular Communication | Waist-to-height ratio (WHtR) was used as a central obesity index and C-reactive protein (CRP) was used as an index for inflammation. | 24247217 |
| Inflammation, Chronic Kidney Diseases, Obesity | Altered Intercellular Communication | Central obesity is also associated with inflammation and the presence of inflammation modifies the associations of central obesity and CKD. | 24247217 |
| Inflammation, Ischemic stroke | Altered Intercellular Communication | Here, the authors assessed this issue, in 48 patients without significant clinical history for major medical illnesses or other factors that promote inflammation, 72 hours after a first-ever acute ischemic stroke. | 24247852 |
| Blepharitis, Inflammation, Intermittent exacerbations | Altered Intercellular Communication | is blepharitis, a chronic inflammation of the eyelid margin with intermittent exacerbations, which is very common in ophthalmic practice. | 24248163 |
| Rosacea | Altered Intercellular Communication | Rosacea is a chronic inflammatory condition that affects the skin of the face and the eyes. | 24248990 |
| Inflammation, CST9 gene | Altered Intercellular Communication | After treatment for CLM with albendazole (800 mg/d for 3 days) and after resolution of perifocal edema and inflammation the typical serpiginous tracks became more obvious. | 24249319 |
| Inflammation, Carcinoma of lung | Altered Intercellular Communication | Circulating inflammation markers and prospective risk for lung cancer. | 24249745 |
| Inflammation, Carcinogenesis, Carcinoma of lung | Altered Intercellular Communication | Despite growing recognition of an etiologic role for inflammation in lung carcinogenesis, few prospective epidemiologic studies have comprehensively investigated the association of circulating inflammation markers with lung cancer. | 24249745 |
| Inflammation, Carcinoma of lung | Altered Intercellular Communication | Some circulating inflammation marker levels are associated with prospective lung cancer risk. | 24249745 |
| Inappropriate ADH Syndrome | Altered Intercellular Communication | Syndrome of inappropriate antidiuretic hormone associated with aripiprazole. | 24249761 |
| Inflammation, Choroidal Effusions | Altered Intercellular Communication | Examination revealed bilateral hypotony, right anterior chamber inflammation, and right choroidal effusion. | 24251433 |
| allergic inflammation | Altered Intercellular Communication | Further studies are needed to determine whether allergic inflammation contributes toward epileptogenesis. | 24251558 |
| Intracerebroventricular route | Altered Intercellular Communication | Treatment of congenital neurotransmitter deficiencies by intracerebral ventricular injection of an adeno-associated virus serotype 9 vector. | 24251946 |
| Orbital Pseudotumor | Altered Intercellular Communication | Immunohistochemical staining is used to diagnose IgG4-RD in patients with orbital inflammation. | 24252013 |
| Dacryoadenitis | Altered Intercellular Communication | Among the nine patients, eight had dacryoadenitis, one had infraorbital nerve swelling, and another one had IgG4-related orbital inflammation. | 24252013 |
| Stomatitis, Nasopharyngitis, Reduced | Altered Intercellular Communication | Frequent adverse events for 52 weeks in the iguratimod + MTX group were nasopharyngitis, upper respiratory tract inflammation, stomatitis, lymphocyte decrease, AST increase, ALT increase and blood iron decrease. | 24252050 |
| Senile Plaques, Inflammation, Cerebral Ischemia | Altered Intercellular Communication | Our results suggest that the reduction in ferroportin levels are likely associated with cerebral ischaemia, inflammation, the loss of neurons due to the well-characterised protein misfolding, senile plaque formation and possibly the ageing process itself. | 24252754 |
| Granulomatous inflammation | Altered Intercellular Communication | Histological examination revealed a necrotising granulomatous inflammation, culture showed a Mycobacterium avium complex (MAC). | 24252838 |
| Refractory anemias, Inflammation | Altered Intercellular Communication | Addition of pioglitazone to RA standard of care significantly improves aortic elasticity and decreases inflammation and disease activity with minimal safety issues. | 24252844 |
| Inflammation, Myopathy | Altered Intercellular Communication | Muscle biopsy showed a necrotizing myopathy with no inflammation or autoimmune changes. | 24252882 |
| Inflammation, Colorectal Carcinoma, Neoplasms | Altered Intercellular Communication | Progression of colorectal cancer (CRC) is strongly associated with inflammation and other desmoplastic reactions in the tumor cell-surrounding tissue. | 24253852 |
| Inflammation, Stomach Carcinoma, Neoplasms | Altered Intercellular Communication | Postoperative complications that can cause prolonged inflammation have an obvious impact not only on the OS but also on the DSM of patients with gastric cancer even if the tumor is resected curatively. | 24254205 |
| Inflammation, Fibrosis Assessment, Non-alcoholic Fatty Liver Disease | Altered Intercellular Communication | Although nonalcoholic fatty liver disease (NAFLD) is conventionally assessed histologically for lobular features of inflammation, development of portal fibrosis appears to be associated with disease progression. | 24254368 |
| Inflammation, Fibrosis Assessment, Non-alcoholic Fatty Liver Disease, GDC Disease Response Terminology | Altered Intercellular Communication | The presence of portal inflammation in NAFLD was strongly correlated with disease severity (fibrosis stage) and the DR. | 24254368 |
| Inflammation, Non-alcoholic Fatty Liver Disease, Histopathologic Grade differentiation | Altered Intercellular Communication | Knowledge of the complex cellular composition of the portal inflammatory infiltrate and HPC/DR niche in NAFLD will shape future functional studies to elucidate the contribution of portal inflammation to HPC differentiation and NAFLD pathogenesis. | 24254368 |
| Dermatitis | Altered Intercellular Communication | Among them 20 cases went to see a doctor for painless mass, and two cases shown as skin inflammation. | 24257306 |
| Inflammation, Cardiovascular Diseases, Endothelial dysfunction, Atherosclerosis | Altered Intercellular Communication | Altered microRNA expression has been reported in processes related to cardiovascular disease and PM exposure, such as systemic inflammation, endothelial dysfunction, and atherosclerosis. | 24257509 |
| Inflammation, Hyperplasia, Neoplasms | Altered Intercellular Communication | Stromal inflammation and increased microvessel density was evident in EAF2-deficient mice on a pure C57BL/6J background at an early age and preceded the development of the histologic epithelial hyperplasia and neoplasia found in the prostates of older EAF2(-/-) animals. | 24260246 |
| Inflammation, Aortic Aneurysm, Abdominal | Altered Intercellular Communication | Periostin links mechanical strain to inflammation in abdominal aortic aneurysm. | 24260297 |
| Inflammation, Glucocorticoid deficiency with achalasia, Aortic Aneurysm, Abdominal | Altered Intercellular Communication | Abdominal aortic aneurysms (AAAs) are characterized by chronic inflammation, which contributes to the pathological remodeling of the extracellular matrix. | 24260297 |
| APP gene, Inflammation | Altered Intercellular Communication | Although mechanical stress has been suggested to promote inflammation in AAA, the molecular mechanism remains uncertain. | 24260297 |
| Inflammation | Altered Intercellular Communication | Our findings indicated that periostin plays an important role in mechanotransduction that maintains inflammation via FAK activation in AAA. | 24260297 |
| Inflammation, diabetic | Altered Intercellular Communication | Diabetic patients could do as well as non-diabetic patients without inflammation on peritoneal dialysis. | 24260402 |
| palladium, Inflammation, diabetic | Altered Intercellular Communication | Diabetic patients on peritoneal dialysis (PD) have lower survival and are more likely complicated with inflammation than their non-diabetic counterparts. | 24260402 |
| palladium, Inflammation, Diabetes Mellitus | Altered Intercellular Communication | Here, we explored the interaction effects between diabetes and inflammation on the survival of PD patients. | 24260402 |
| palladium, Inflammation | Altered Intercellular Communication | Diabetics on PD were more likely to have inflammation than non-diabetics on PD, and they presented with elevated hsCRP (52.7% vs. 47.3%, P = 0.03) or decreased SA (77.9% vs. 62.7%, P < 0.001) levels. | 24260402 |
| Inflammation, diabetic | Altered Intercellular Communication | Diabetic patients could do as well as non-diabetic patients without inflammation on peritoneal dialysis. | 24260402 |
| palladium, Inflammation, diabetic | Altered Intercellular Communication | Active strategies should be implemented to improve inflammation status in diabetic patients on PD. | 24260402 |
| Diabetes Mellitus, Cardiovascular system | Altered Intercellular Communication | Then, several multivariable adjusted stratified Cox regression models were constructed for these groups to explore the predicted role of diabetes on all-cause or cardiovascular death under inflammatory or non-inflammatory conditions. | 24260402 |
| Inflammation | Altered Intercellular Communication | The role of inflammasomes in chronic inflammation has been the subject of intense research in recent years. | 24260763 |
| Inflammation, Acid reflux | Altered Intercellular Communication | Catheter substitution was necessary in three patients during the first year, because of stoma inflammation due to enteric reflux between the stoma and the catheter. | 24261024 |
| Inflammation | Altered Intercellular Communication | Inflammation may be important in contributing to EHG and warrants further investigation. | 24262327 |
| Inflammation | Altered Intercellular Communication | Patients with HFpEF often show signs of chronic systemic inflammation, and experimental studies have shown that interleukin-1 (IL-1), a key proinflammatory cytokine, impairs myocardial relaxation. | 24262762 |
| Granulomatosis, Systemic Vasculitis, Acute sinusitis | Altered Intercellular Communication | Although granulomatosis with polyangiitis (GPA) can affect a large number of organ systems and produce a broad spectrum of clinical symptoms, skeletal involvement is very rare, with the exception of facial bone involvement associated with destructive nasal and sinus inflammation. | 24263148 |
| Necrotizing granulomatous inflammation, Fibrinoid necrosis | Altered Intercellular Communication | A histopathologic analysis of the lung mass revealed chronic granulomatous inflammation with fibrinoid necrosis, and he was diagnosed with GPA. | 24263148 |
| Inflammation, Respiratory Hypersensitivity, Inflammatory disorder | Altered Intercellular Communication | Asthma is a chronic inflammatory disorder of the airways that is characterized by episodic and reversible airflow obstruction, airway hyper-responsiveness, and underlying inflammation. | 24264497 |
| Inflammation, Periodontitis, Infection, Pneumonia | Altered Intercellular Communication | The chronic infections associated with periodontitis can increase the risk for aspiration pneumonia in older adults and has been implicated in the pathogenesis of chronic inflammation that impairs general health. | 24264502 |
| Gingivitis, Attachment (action), Periodontal Diseases | Altered Intercellular Communication | The severity of periodontal disease can be categorized as mild, moderate, or severe on the basis of multiple measurements of periodontal pocket depth, attachment loss, and gingival inflammation around teeth. | 24264502 |
| Granulomatous inflammation, Vasculitis, CTCAE | Altered Intercellular Communication | Nasal biopsy revealed granulomatous inflammation and vasculitis involving small vessels. | 24265538 |
| Schistosomiasis mansoni, Nephritis | Altered Intercellular Communication | Monocyte chemotactic protein-1 (MCP-1) in patients with chronic schistosomiasis mansoni: evidences of subclinical renal inflammation. | 24265821 |
| Inflammation, Traumatic injury | Altered Intercellular Communication | This protein has a role in the recruitment of monocytes to injury and inflammation sites . | 24265821 |
| Nephritis | Altered Intercellular Communication | The increase of MCP-1 in the urine evidences that there is silent renal inflammation in these patients and the inflammatory status is not interrupted by specific treatment of the offending agent. | 24265821 |
| Necrotizing granulomatous inflammation, Glomerulonephritis, Vasculitis, CTCAE | Altered Intercellular Communication | It is manifested as granulomatous necrotizing inflammation of the upper and lower parts of the respiratory tract, glomerulonephritis and systemic vasculitis involving most frequently the skin and oral mucous membrane. | 24266321 |
| Inflammation, Diverticular Diseases | Altered Intercellular Communication | Since diverticular disease appeared slight and no inflammation signs were evident, colon resection was not performed. | 24267118 |
| Inflammation, Choline Dehydrogenase, Mitochondrial | Altered Intercellular Communication | Inflammatory factors and low HDL-C relate to CHD risk, but whether inflammation attenuates any protective association of high HDL-C is unknown. | 24267235 |
| Choline Dehydrogenase, Mitochondrial | Altered Intercellular Communication | Compared to high HDL-C/low-inflammation categories (referent), adjusted HRs for incident CHD were increased for those with high HDL-C and high CRP (HR = 1.50, p < 0.01) or highest IL-6 tertile (HR = 1.40, p < 0.05), but not with highest Lp-PLA2 tertile. | 24267235 |
| Inflammation, Choline Dehydrogenase, Mitochondrial | Altered Intercellular Communication | The protective relation of high HDL-C for incident CHD appears to be attenuated by greater inflammation. | 24267235 |
| Inflammation, Heparin-induced thrombocytopenia, Dental Plaque, Atherosclerosis | Altered Intercellular Communication | Our data demonstrate that heparin-induced mobilization of vessel-bound MPO is closely linked to coronary plaque burden and thus further corroborate the evidence for the intimate involvement of this enzyme in vascular pathophysiology, as well as the importance of inflammation in atherosclerosis. | 24267251 |
| Hypertension, CTCAE, Dermatitis | Altered Intercellular Communication | Chronic skin inflammation may plays a role in the aetiology of hypertension in both disorders. | 24267636 |
| Primary malignant neoplasm, Colitis | Altered Intercellular Communication | In animal models, excess luminal iron exacerbates colonic inflammation and cancer development. | 24267915 |
| Inflammation | Altered Intercellular Communication | Inflammation is likely to play a role because steroids often improve these phenomena. | 24267950 |
| Idiopathic aortitis | Altered Intercellular Communication | Idiopathic aortitis (IA) is characterized by giant cell or lymphoplasmacytic inflammation of aorta without a secondary cause. | 24268116 |
| Inflammation, Obesity, Diabetes Mellitus | Altered Intercellular Communication | Resistin is a peptide hormone that is secreted from lipid cells and is linked to type-2 diabetes, obesity, and inflammation. | 24268420 |
| Inflammation, Obesity, Diabetes Mellitus | Altered Intercellular Communication | Resistin is a peptide hormone that is secreted from lipid cells and is linked to type-2 diabetes, obesity, and inflammation. | 24268420 |
| Arterial Stiffness, Mucopolysaccharidosis I | Altered Intercellular Communication | Although yet to be confirmed, increased cIMT and arterial stiffness in MPS I and II patients may be a consequence of inflammatory signaling pathways triggered by heparan or dermatan sulfate-derived oligosaccharides. | 24268528 |
| Osteomyelitis, Discitis | Altered Intercellular Communication | Gallium inflammation scan and magnetic resonance image of the spine disclosed osteomyelitis and discitis at the level of L4-5. | 24269007 |
| Inflammation, SDSL gene | Altered Intercellular Communication | Aberrant angiogenesis and localized inflammation contribute to the formation of CSDH. | 24269089 |
| Inflammation | Altered Intercellular Communication | Mesenchymal cells (fibroblasts) of the airway wall respond to cholinergic stimulation by releasing pro-inflammatory and chemotactic cytokines and may thus contribute to chronic inflammation of the lung. | 24269928 |
| Pulmonary arterial hypertension, Inflammation, Polycyclic Hydrocarbons, Aromatic | Altered Intercellular Communication | Pulmonary arterial hypertension (PAH) is associated with sustained inflammation known to promote DNA damage. | 24270264 |
| Tumor necrosis, Inflammation | Altered Intercellular Communication | Healthy PASMCs treated with a clinically relevant dose of tumor necrosis factor-a harbored a similar phenotype, suggesting that inflammation induces DNA damage and PARP-1 activation in PAH. | 24270264 |
| Arterial Stiffness, Inflammation, Dyslipidemias, Obesity | Altered Intercellular Communication | These findings suggest that EPA improves the arterial stiffness in association with an increase in the EPA/AA ratio and a decrease in inflammation in obese patients with dyslipidemia. | 24270918 |
| Inflammation | Altered Intercellular Communication | The transcription factor PPAR-g plays various roles in lipid metabolism, inflammation, cellular differentiation, and apoptosis. | 24272485 |
| Inflammation | Altered Intercellular Communication | Contrast medium suppresses FMD, probably through an increased production of oxygen-derived free radicals and inflammation although adequate hydration was given in type 2 diabetes. | 24272602 |
| N-formyl-13-dihydrocarminomycin, Inflammation, Presenile dementia | Altered Intercellular Communication | These findings demonstrate that microglial activation does not initiate or exacerbate NFD, and we conclude that CNS inflammation is unlikely to be causally involved in the development of NFD characteristic of AD dementia. | 24272705 |
| Infarction, Inflammation, Ischemic | Altered Intercellular Communication | Inflammation may not only be the consequence of brain infarction but it may also contribute to ischemic damage. | 24273300 |
| Inflammation, Dermatologic disorders, Toxic Epidermal Necrolysis, Necrosis | Altered Intercellular Communication | Toxic epidermal necrolysis (TEN) is an idiosyncratic, potentially life-threatening skin disease characterized by widespread inflammation and necrosis of the epidermis and mucous membranes. | 24273804 |
| Inflammation, Malnutrition, Chronic Kidney Diseases | Altered Intercellular Communication | The aim of the present study was to test the hypothesis whether serum resistin is associated with markers of malnutrition and inflammation in elderly non-diabetic adults in different stages of CKD including hemodialysis. | 24273936 |
| Chronic Kidney Diseases | Altered Intercellular Communication | These results indicate that resistin increases as GFR declines and may be involved in the malnutrition-inflammation state and the reverse epidemiology phenomenon present in elderly, non-diabetic patients with CKD. | 24273936 |
| Inflammation, Chronic sinusitis | Altered Intercellular Communication | Does eosinophilic inflammation affect the outcome of endoscopic sinus surgery in chronic rhinosinusitis in Koreans? | 24274208 |
| Inflammation, Chronic sinusitis, Craniosynostosis | Altered Intercellular Communication | The implication of eosinophilic inflammation in chronic rhinosinusitis (CRS) has not been sufficiently studied in Asians. | 24274208 |
| Inflammation, Craniosynostosis | Altered Intercellular Communication | The results suggest that eosinophilic inflammation in CRS may not be related to the surgical outcome in Koreans. | 24274208 |
| Arthralgia, Inflammation, Knee pain | Altered Intercellular Communication | Patterns of change in SF-36, systemic inflammation biomarkers, and the 6-minute walk test did not differ significantly between groups during the 8-week study Results from this randomized, double blind, placebo-controlled community trial support the use of the Instaflex(tm) dietary supplement in alleviating joint pain severity in middle-aged and older adults, with mitigation of difficulty performing daily activities most apparent in subjects with knee pain. | 24274358 |
| Inflammation, Toxic effect | Altered Intercellular Communication | Concurrent chemoradiotherapy (CCRT) induces toxicities from inflammation and immunological suppression. | 24274379 |
| Inflammation, Squamous cell carcinoma of esophagus | Altered Intercellular Communication | The question is whether immunonutrition (IN) during CCRT reduces inflammation and improves the immune function in patients with esophageal squamous cell carcinoma (ESCC). | 24274379 |
| Crohn Disease, Inflammatory disease of mucous membrane | Altered Intercellular Communication | Dysbiosis of gut fungal microbiota is associated with mucosal inflammation in Crohn's disease. | 24275714 |
| Inflammatory disease of mucous membrane | Altered Intercellular Communication | Shifts of gut fungal microbiota composition may be associated with mucosal inflammation and disease activity of CD. | 24275714 |
| Toxic effect, Diarrhea, Leukopenia, Inflammatory disease of mucous membrane | Altered Intercellular Communication | The toxicity profile was similar across age groups, with the exception of diarrhea, mucosal inflammation, and grade 3-4 neutropenia and leukopenia, which were slightly more common in elderly patients in both treatment arms. | 24277116 |
| Inflammation, Impaired, Uveitis | Altered Intercellular Communication | In Cohort 1, only one patient was symptomatic for ocular impairment, and uveitis without inflammation was the most common presentation. | 24277596 |
| Malnutrition, Pneumonitis, Osteopenia | Altered Intercellular Communication | The mechanism for early bone loss in CF patients are multifactorial: chronic pulmonary inflammation, malnutrition, reduced physical activity, delayed pubertal maturation. | 24277958 |
| Visual Impairment, Vasculitis, CTCAE, Vitreous inflammatory cells | Altered Intercellular Communication | Significant differences were found for size of active lesions, unilateral macular involvement, unilateral visual impairment, vitreous inflammation, synechiae, and vasculitis, with higher values observed throughout for Colombian patients. | 24278490 |
| Inflammation, Carcinogenesis | Altered Intercellular Communication | Other protein modifications related to carcinogenesis and inflammation and the various factors that may play a role in orchestrating complex interactions which influence tissue integrity following irradiation were investigated. | 24279338 |
| Inflammation, Obesity, Choline Dehydrogenase, Mitochondrial | Altered Intercellular Communication | Chronic inflammation and risk factors, such as obesity, smoking, and high cholesterol, are well-established risk factors for CHD. | 24279678 |
| ARCN1 gene, Inflammation | Altered Intercellular Communication | COPD is characterized by chronic inflammation in the pulmonary compartment and in the systemic circulation. | 24281671 |
| Inflammation, Dental Plaque, Rupture | Altered Intercellular Communication | Biomarkers of endothelial inflammation (hsCRP), plaque destabilization, and rupture (sVCAM, MMP-9, PAPP-A, ADMA) were quantified. | 24281903 |
| Inflammation, thromboembolic, atherosclerotic, Atherosclerotic lesion | Altered Intercellular Communication | Identification of inflamed atherosclerotic lesions in vivo using PET-CT. Inflammation plays a major pathogenetic role in the development of atherosclerotic plaques and related thromboembolic events. | 24282108 |
| Inflammation | Altered Intercellular Communication | Fluorodeoxyglucose positron emission tomography (FDG-PET) has been shown to be useful for tracing inflammation within plaques. | 24282108 |
| Obstructive Ureterocele | Altered Intercellular Communication | This finding suggests that FDG uptake reflects the severity of atherosclerotic vessel wall inflammation, and in stenotic lesions, it could be an indicator of their vulnerability. | 24282108 |
| Dry Eye Syndromes, Diabetes Mellitus | Altered Intercellular Communication | Analysis of spectral counts of tear proteins showed that, compared to healthy controls, patients with diabetes and dry eye syndrome had increased expression of apoptosis-related proteins, like annexin A1, and immunity- and inflammation-related proteins, including neutrophil elastase 2 and clusterin, and glycometabolism-related proteins, like apolipoprotein A-II. | 24282230 |
| Gingivitis, Impaired cognition, Disease | Altered Intercellular Communication | The association of lower cognitive scores with edentulism suggests that past oral diseases may be a risk indicator for cognitive decline, whereas the association with gingival inflammation indicates a possible effect of cognitive decline on oral health. | 24282266 |
| Inflammation, Fibrosis Assessment, Atrophic | Altered Intercellular Communication | Tissue KIM-1 expression was determined immunohistochemically and KIM-1 staining was scored semiquantitatively, as well as tubulointerstitialis (TIN), inflammation, atrophy, and fibrosis. | 24282337 |
| Allergic asthma, physiopathological, Airway structure | Altered Intercellular Communication | Allergic asthma is characterized by airway inflammation in response to antigen exposure, leading to airway remodeling and lung dysfunction. | 24283210 |
| Inflammation, Vascular System Injuries | Altered Intercellular Communication | Deletion of thioredoxin-interacting protein preserves retinal neuronal function by preventing inflammation and vascular injury. | 24283717 |
| Retinal Ganglion Cells, Retinitis | Altered Intercellular Communication | Targeting TXNIP expression prevented early retinal ganglion cell death, glial activation, retinal inflammation and secondary neuro/microvascular degeneration and preserved retinal function. | 24283717 |
| Inflammation | Altered Intercellular Communication | Interleukin-1 plays a key role in inflammation and keratinocyte activation. | 24283773 |
| Inflammation, Fibrosis Assessment, Colonic Diverticulitis, Crohn Disease | Altered Intercellular Communication | Inflammation and fibrosis are present in both colonic diverticulitis and Crohn's disease (CD). | 24283919 |
| Inflammation | Altered Intercellular Communication | Lymphocytic and neutrophil inflammation scores were similar in both groups (P = 0.771 and P = 0.562). | 24283919 |
| Inflammation | Altered Intercellular Communication | The findings confirm that inflammation and its association with altered molecular patterns of mucosal healing may play an important role in the phenotype of the diseases. | 24283919 |
| Inflammation | Altered Intercellular Communication | eGFR level in CAD patients with normal serum creatinine is associated with coronary artery severity, inflammation level and serves as an independent predictor for MACCE in this patient cohort. | 24284182 |
| Refractory anemias, Inflammation, Rheumatoid Arthritis, Anemia | Altered Intercellular Communication | Anemia of inflammation (AI) is a common complication of rheumatoid arthritis (RA) and has a negative impact on RA symptoms and quality of life. | 24286116 |
| Inflammation, hafnium, Depression, CTCAE | Altered Intercellular Communication | Hence, the goal is to examine the relative importance of inflammation, disease severity and personality as predictors of depression in HF patients. | 24286171 |
| Inflammation, Depression, CTCAE | Altered Intercellular Communication | Inflammation, brain natriuretic peptide and left ventricular ejection fraction were not related to depression over time. | 24286171 |
| Inflammation, Bipolar Disorder | Altered Intercellular Communication | Personality factors, but not inflammation, were independent concomitants of depressive symptoms in patients with HF. | 24286171 |
| Refractory anemias, Rheumatoid Arthritis, Chronic inflammation, Atherosclerosis | Altered Intercellular Communication | Rheumatoid arthritis (RA) is a complex polygenic disease associated with chronic inflammation, accelerated atherosclerosis and increased cardiovascular (CV) mortality. | 24286297 |
| methyldopa, Inflammation | Altered Intercellular Communication | Evidence indicates that the suppression of the ubiquitin-proteasome system (UPS) contributes to the accumulation of toxic proteins and inflammation in retinal pigment epithelium (RPE), the functional abnormalities and/or the degeneration of which are believed to be the initiators and major pathologies of AMD. | 24286321 |
| Refractory anemias, Rheumatoid Arthritis, Damage, Inflammation | Altered Intercellular Communication | Oncostatin M (OSM) has been implicated in the pathophysiology of rheumatoid arthritis (RA) through its effect on inflammation and joint damage. | 24286335 |
| Inflammation, Nephritis | Altered Intercellular Communication | These data suggest that serum levels of LL37 and IFN-a may reflect both local renal inflammation and systemic inflammation. | 24286516 |
| Inflammation, Immune dysregulation, Arthritis | Altered Intercellular Communication | However, some patients have persistent arthritis after spirochetal killing, which may result from excessive inflammation, immune dysregulation and infection-induced autoimmunity. | 24286535 |
| Inflammation, Arthritis | Altered Intercellular Communication | In patients with antibiotic-refractory arthritis, the frequencies of IFN-g-producing CD56bright and CD56dim NK cells remained high in SF, even after spirochetal killing, suggesting that these cells contribute to excessive inflammation and immune dysregulation in joints, and iNKT cells, which may have immunomodulatory effects, were often absent. | 24286535 |
| Chronic infectious disease, Inflammation, Traumatic injury, Neoplasms | Altered Intercellular Communication | Commonly mucoceles form secondary to obstruction of a sinus outflow tract or from mucosal gland entrapment from chronic infection, inflammation, iatrogenic trauma, external trauma, or neoplasm. | 24286944 |
| Inflammation, muscle mass | Altered Intercellular Communication | These findings in a limited group of individuals suggest that regular physical endurance activity may play a role in reducing some markers of systemic inflammation, even within the normal range, and in maintaining muscle mass with aging. | 24287006 |
| Inflammation, Ischemic stroke | Altered Intercellular Communication | Clinical and experimental data have demonstrated that inflammation plays fundamental roles in the pathogenesis of ischemic stroke. | 24288444 |
| Refractory anemias, Inflammation, Endothelial dysfunction | Altered Intercellular Communication | Classical CVD risk factors and inflammation are both implicated in causing endothelial dysfunction in RA. | 24289091 |
| Refractory anemias, Inflammation, Atherosclerosis | Altered Intercellular Communication | Classical CVD risk factors, but not RA disease-related inflammation, predicted microvascular endothelium-dependent and endothelium-independent function, macrovascular endothelium-independent function and carotid atherosclerosis. | 24289091 |
| Inflammation, Atherosclerosis | Altered Intercellular Communication | Cumulative inflammation was not associated with microvascular and macrovascular endothelial function, but a weak association was apparent between area under the curve for CRP and carotid atherosclerosis. | 24289091 |
| Refractory anemias, Inflammation | Altered Intercellular Communication | Classical CVD risk factors may be better long-term predictors of vascular function and morphology than systemic disease-related inflammation in patients with RA. | 24289091 |
| Inflammation, Global systolic dysfunction | Altered Intercellular Communication | Our study is the first to demonstrate an association between serum CA 125 levels and LV systolic dysfunction via inflammation in patients on maintenance HD. | 24289262 |
| Inflammation, Damage, Obesity, Abdominal, Diabetes Mellitus, Non-Insulin-Dependent | Altered Intercellular Communication | Abdominal obesity and low-grade systemic inflammation as markers of subclinical organ damage in type 2 diabetes. | 24290615 |
| Sandawe language, Inflammation, Atherosclerosis, Obesity, Arterial Stiffness, Damage, Diabetes Mellitus, Non-Insulin-Dependent | Altered Intercellular Communication | Both SAD and WC are feasible measures of obesity, and both provide information on inflammation, atherosclerosis and arterial stiffness in type 2 diabetes, while SAD appears to be slightly more robustly associated with subclinical organ damage than WC. | 24290615 |
| Inflammation, Periprosthetic Fractures, Osteolysis | Altered Intercellular Communication | Patient radiographs were scored for osteolysis and periprosthetic tissues were immunostained and imaged to quantify polyethylene wear, inflammation, and five osteoinflammatory and oxidative stress-responsive factors. | 24290740 |
| Inflammation, Osteolysis | Altered Intercellular Communication | Similar to wear debris and inflammation, osteolysis correlated with HMGB1. | 24290740 |
| Inflammation, Typhoid Fever | Altered Intercellular Communication | Further, the increase in albumin and haptoglobin in chronic typhoid carriers shows their role in free radical generation, inflammation, and monocyte cell signaling. | 24291468 |
| Inflammation, Pancreatitis, Necrosis | Altered Intercellular Communication | The infiltration of surrounding tissue and nearby organs by inflammation and fat necrosis in necrotizing pancreatitis has not been reported previously in a pediatric patient. | 24292046 |
| Inflammation | Altered Intercellular Communication | Inflammation has previously been shown to increase levels of extracellular b-nicotinamide adenine dinucleotide (NAD(+)). | 24292505 |
| Inflammation, Endothelial dysfunction, ETV3 wt Allele, Cardiovascular Diseases | Altered Intercellular Communication | Furthermore, we show that the presence of the MetS is characterized by endothelial dysfunction, as suggested by lower fRHI, as well as by endothelial inflammation, which likely contributes to the increased cardiovascular disease risk associated with the MetS. | 24292639 |
| Inflammation, Lymphoma, Leukemia, T-Cell | Altered Intercellular Communication | HTLV-I bZIP factor (HBZ), which is expressed in all adult T-cell leukemia cells, plays a critical role in the development of lymphoma and systemic inflammation. | 24292748 |
| Pneumonitis | Altered Intercellular Communication | HBZ and Foxp3 likely have a role in the development of lung inflammation. | 24292748 |
| Inflammation, Brain Injuries | Altered Intercellular Communication | It may contribute to chronic inflammation and tissues injury. | 24292797 |
| Inflammation, Osteoarthritis, Knee | Altered Intercellular Communication | Effect of low-dose oral prednisolone on symptoms and systemic inflammation in older adults with moderate to severe knee osteoarthritis: a randomized placebo-controlled trial. | 24293578 |
| Pain Distress Question, Inflammation | Altered Intercellular Communication | Outcome measures included pain reduction and improvement in function scores and systemic inflammation markers. | 24293578 |
| ARCN1 gene, Inflammation | Altered Intercellular Communication | Effect of high-dose N-acetylcysteine on airway geometry, inflammation, and oxidative stress in COPD patients. | 24293993 |
| Inflammation, Diverticulum, Diverticulosis | Altered Intercellular Communication | On the basis of morphological and immunological study of biopsies of the colon in patients with diverticulosis was revealed that microscopic inflammation of the mouth of the diverticulum is characterized by several features that include excessive proliferation of the epithelium, the predominance of macrophage reaction in the development of the immune response, increased cell adhesion and unusual ratio between the expression of cytokines and other regulatory molecules. | 24294770 |
| Inflammation, Fibrosis Assessment | Altered Intercellular Communication | Serum TNF-alpha and IL-6 have predictive value for development of inflammation and fibrosis in patients with AH and can be used as non-invasive markers of fibrosis. | 24294778 |
| Inflammation, hepcidin | Altered Intercellular Communication | This improvement correlates with the degree of suppression of systemic inflammation, reduction in hepcidin and haptoglobin and increase in iron-binding capacity. | 24295403 |
| Inflammation, Stomach Carcinoma | Altered Intercellular Communication | Study of TLR4 and IL-8 gene polymorphisms in H.pylori-induced inflammation in gastric cancer in an ethnic Kashmiri population. | 24295404 |
| Inflammatory abnormality of the eye, Infection by human herpesvirus 6 | Altered Intercellular Communication | Recurrent ocular surface inflammation associated with human herpesvirus 6 infection. | 24296955 |
| Degenerative polyarthritis, Inflammation | Altered Intercellular Communication | Recent evidence suggests that angiogenesis and inflammation contribute to the development and progression of osteoarthritis (OA). | 24297611 |
| Inflammation, Non-Small Cell Lung Carcinoma, Neoplasms | Altered Intercellular Communication | Low-serum sodium concentration, which was associated with tumor status and inflammation, had negative prognostic influence in completely resected NSCLC. | 24297635 |
| Cerebral Vasospasm | Altered Intercellular Communication | Therefore, further research should focus on anti-inflammation as a therapeutic target against cerebral vasospasm and on the CSF as the optimum place where such inflammatory action practically brought about. | 24297765 |
| Autoimmune Diseases, Myasthenia Gravis | Altered Intercellular Communication | Myasthenia gravis (MG) is a severely debilitating autoimmune disease that is due to a decrease in the efficiency of synaptic transmission at neuromuscular synapses. | 24297891 |
| Communicable Diseases, Inflammation | Altered Intercellular Communication | The exposed tube was closed successfully without recurrence, graft thinning, or graft-related infection or inflammation over a 20-month follow-up period. | 24299729 |
| Inflammation | Altered Intercellular Communication | Acute inflammation was histologically proven in 18/18 specimens (100%) and additional chronic inflammation in 12/18 (66.7%). | 24300350 |
| Inflammation | Altered Intercellular Communication | Group One patients were found to have a significantly higher level of the marker of chronic inflammation IgG and IL-8, amounting respectively to 22.43+-0.75 mg/ml and to 6.34+-1.008 pg/ml and 16.35+-0.84 mg/ml (p=0.01) and 3.96+-0.399 pg/ml (p=0.01) in Group Two patients. | 24300501 |
| Communicable Diseases, Observation Method - Coagulation, Inflammation, HIV-1 Infection Pathway | Altered Intercellular Communication | Inflammation and coagulation biomarkers interleukin (IL)-6 and D-dimer are predictive of all-cause mortality in chronic HIV-1 infection; however, their predictive value in individuals with recent infection has not been described. | 24300544 |
| Acute inflammation, Chronic Acalculous Cholecystitis | Altered Intercellular Communication | Good results were obtained in 93% of patients with chronic calculous cholecystitis, as well as acute inflammation. | 24300608 |
| Schizophrenia, Chronic disease, Unipolar Depression | Altered Intercellular Communication | In chronic diseases such as schizophrenia and major depression, decrease in astroglial numbers and functional capabilities are, arguably, fundamental for pathological developments being responsible for neurotransmitter disbalance and failures in connectivity within neural networks. | 24301046 |
| Inflammation, SERPINB3 wt Allele | Altered Intercellular Communication | In conclusion, these results suggested that the G allele of the CCR5 59029 polymorphism might be a risk factor due to the loss of receptor function that might cause increased inflammation leading to the development of OSCC. | 24301940 |
| Inflammation, Phenylketonurias | Altered Intercellular Communication | Phenylketonuria is not a risk factor for gut mucosa inflammation: a preliminary observation. | 24302186 |
| Inflammation | Altered Intercellular Communication | In PKU high oxidative stress and inefficiency of free radical scavenging may lead to systemic chronic inflammation. | 24302186 |
| Inflammation, Obesity | Altered Intercellular Communication | Obesity is associated with insulin resistance and chronic low-grade inflammation. | 24302564 |
| Inflammation, Fibrosis Assessment, Fatty degeneration, FAM126A gene | Altered Intercellular Communication | A biopsy confirmed the suspected diagnosis of HCC; interestingly, the non-neoplastic liver was surrounded and characterized by the presence of steatosis and ballooning, and being absent of lobular inflammation and fibrosis. | 24302697 |
| Non-alcoholic Fatty Liver Disease, Diabetes Mellitus, Non-Insulin-Dependent | Altered Intercellular Communication | Low serum sex hormone-binding globulin is associated with nonalcoholic fatty liver disease in type 2 diabetic patients. | 24303796 |
| Inflammation, Peyronie Disease | Altered Intercellular Communication | Long-term multimodal therapy (verapamil associated with propolis, blueberry, vitamin E and local diclofenac) on patients with Peyronie's disease (chronic inflammation of the tunica albuginea). | 24304332 |
| Inflammation, Primary malignant neoplasm | Altered Intercellular Communication | Systemic inflammation has been implicated in cancer development and progression. | 24306668 |
| Inflammation, Carcinogenesis, Squamous cell carcinoma of esophagus | Altered Intercellular Communication | These results suggest, for the first time, that upregulation of PLCE1 is correlated with increased expression of NF-kB-related proteins in Kazakh patients with ESCC, suggesting that interaction between PLCE1 with the NF-kB signal pathway may be responsible for the carcinogenesis of ESCC, such as ESCC-related inflammation. | 24307345 |
| Acute myocardial infarction, Inflammation, Dental Plaque | Altered Intercellular Communication | The presence of CX3CR1 polymorphisms could influence the incidence and the outcome of acute myocardial infarction, altering the inflammation of the whole coronary tree by the impaired recruitment of Th1 polarized subpopulation in the coronary plaque. | 24307998 |
| Inflammation, Prostate carcinoma | Altered Intercellular Communication | Recent studies suggest that chronic inflammation is crucial in the development and progression of prostate cancer (CaP). | 24308236 |
| Inflammation, Carcinogenesis | Altered Intercellular Communication | Interleukin-6 (IL-6) is a proinflammatory cytokine that plays an important role in intraprostatic inflammation and thus carcinogenesis. | 24308236 |
| Gingivitis | Altered Intercellular Communication | COPB subjects had significantly worse periodontal conditions than controls (p < 0.05) with regard to each parameter of periodontal condition, except for gingival inflammation. | 24308240 |
| Inflammation, Chronic Obstructive Airway Disease | Altered Intercellular Communication | An index of daily step count and systemic inflammation predicts clinical outcomes in chronic obstructive pulmonary disease. | 24308588 |
| Arterial Stiffness, ARCN1 gene, Inflammation | Altered Intercellular Communication | Arterial stiffness in patients with COPD: the role of systemic inflammation and the effects of pulmonary rehabilitation. | 24311762 |
| Arterial Stiffness, Inflammation, Chronic Obstructive Airway Disease, ARCN1 gene | Altered Intercellular Communication | Clear evidence for an association between systemic inflammation and increased arterial stiffness in patients with chronic obstructive pulmonary disease (COPD) is lacking. | 24311762 |
| Arterial Stiffness, ARCN1 gene, Inflammation | Altered Intercellular Communication | Arterial stiffness in COPD is not related to systemic inflammation and does not respond to state-of-the-art pulmonary rehabilitation. | 24311762 |
| Refractory anemias, Rheumatoid Arthritis, Autoimmune Diseases, Inflammation | Altered Intercellular Communication | Rheumatoid arthritis (RA) is a chronic, systemic autoimmune disease with unknown aetiology that causes the immune system to attack the joints (synoviums), leading to chronic inflammation. | 24311851 |
| Fibrosis Assessment, Hepatitis | Altered Intercellular Communication | Liver inflammation and fibrosis, viral load and genotype did not correlate with BMD measurements. | 24312334 |
| Gastritis, Gastritis, Atrophic | Altered Intercellular Communication | These findings demonstrate that cholesteryl a-glucosides play critical roles in H. pylori-mediated gastric inflammation and precancerous atrophic gastritis. | 24312443 |
| Renal Insufficiency, Inflammation, Primary malignant neoplasm | Altered Intercellular Communication | In conclusion, in elderly men, GDF-15 improves prognostication of both cardiovascular, cancer mortality and morbidity beyond established risk factors and biomarkers of cardiac, renal dysfunction and inflammation. | 24312445 |
| Shock, Inflammation, Hypoxia | Altered Intercellular Communication | Trauma/hemorrhagic shock (T/HS) results in hepatic hypoxia that drives inflammation. | 24312451 |
| Inflammation, Idiopathic pulmonary hypertension | Altered Intercellular Communication | Markers of thrombogenesis and fibrinolysis and their relation to inflammation and endothelial activation in patients with idiopathic pulmonary arterial hypertension. | 24312667 |
| Inflammation, Idiopathic pulmonary hypertension | Altered Intercellular Communication | Fibrinolysis, inflammation, and endothelial activation were closely interrelated in IPAH. | 24312667 |
| Streptococcal Infections, Have Autoimmune or Inflammatory Condition, Encephalomyelitis, Acute Disseminated | Altered Intercellular Communication | We suggest that the pathophysiological mechanism in the present case was not necrotic/cytotoxic but autoimmune inflammation, which is compatible with acute disseminated encephalomyelitis associated with streptococcal infection. | 24313006 |
| Inflammation, Metabolic Syndrome X | Altered Intercellular Communication | Strong evidence suggests that systemic inflammation and central adiposity contribute to and perpetuate metabolic syndrome. | 24313349 |
| Inflammation | Altered Intercellular Communication | Macroscopic evaluation of the joints during arthroscopy revealed a significant decrease of local inflammation mainly in good ACR50 responders. | 24313444 |
| Rheumatoid Arthritis, Inflammation | Altered Intercellular Communication | Circulating progenitor cells in rheumatoid arthritis: association with inflammation and oxidative stress. | 24313545 |
| Inflammation, Atherosclerosis, Refractory anemias, Vascular lesions, Rheumatoid Arthritis | Altered Intercellular Communication | To evaluate the association between inflammation, oxidative stress, and circulating progenitor cell (CPC) number and redox equilibrium, vascular lesions and accelerated atherosclerosis in rheumatoid arthritis (RA). | 24313545 |
| Arterial Stiffness, Inflammation, Refractory anemias | Altered Intercellular Communication | Our data show a link between inflammation, oxidative stress, and the impairment of the antioxidant system of CPCs and their number, and with arterial stiffness in RA subjects. | 24313545 |
| Inflammation, Malnutrition, Traumatic injury | Altered Intercellular Communication | Trauma patients with DWH frequently suffer from protein malnutrition and reduced plasma concentrations of several micronutrients probably due to inflammation, increased requirement, and oxidative burden. | 24314073 |
| prostatitis | Altered Intercellular Communication | Relationship of chronic histologic prostatic inflammation in biopsy specimens with serum isoform [-2]proPSA (p2PSA), %p2PSA, and prostate health index in men with a total prostate-specific antigen of 4-10 ng/ml and normal digital rectal examination. | 24315305 |
| Prostate carcinoma, Structure of posterior cerebral artery | Altered Intercellular Communication | To investigate the relationship between serum [-2]proPSA (p2PSA) and derivatives with chronic histologic prostatic inflammation (CHPI) in men undergoing prostate biopsy for suspected prostate cancer (PCa). | 24315305 |
| goal oriented behavior, Toxoplasmosis | Altered Intercellular Communication | Latent T. gondii infection may be of relevance to goal-directed behavior as it alters dopaminergic neural transmission. | 24315729 |
| Inflammatory Bowel Diseases | Altered Intercellular Communication | Inflammatory bowel disease (IBD) is a systemic inflammatory condition that affects the entire organism, not only the bowel. | 24315776 |
| Inflammation | Altered Intercellular Communication | Increasing evidence suggests that systemic inflammation is associated with many pathophysiological processes including frailty in older adults. | 24316038 |
| Inflammation, Diverticular Diseases, Cardiovascular Diseases | Altered Intercellular Communication | Inflammation associated with diverticular disease could predispose to cardiovascular disease. | 24316104 |
| Proteinuria, Nephritis, Kidney Diseases | Altered Intercellular Communication | Urinary cytokines after HCT: evidence for renal inflammation in the pathogenesis of proteinuria and kidney disease. | 24317123 |
| Proteinuria, Inflammation, Albuminuria | Altered Intercellular Communication | After HCT, elevated urinary levels of pro-inflammatory cytokines are associated with development of albuminuria and proteinuria, suggesting early intra-renal inflammation as an important pathogenetic mechanism. | 24317123 |
| Inflammation | Altered Intercellular Communication | Eight patients showed inflammatory extension beyond the lacrimal gland, such as thickened rectus muscle (n = 6), inflammation of the optic nerve (n = 2), and retrobulbar inflammation (n = 3). | 24318531 |
| Inflammation, IgG4-Related Sclerosing Disease, Dacryoadenitis, Allergic | Altered Intercellular Communication | IgG4-related dacryoadenitis showed various ophthalmologic symptoms due to extensive inflammation beyond the lacrimal gland, frequent association with other IgG4-related disease or allergic phenomena, and steroid responsiveness. | 24318531 |
| Inflammation, Diabetes Mellitus, Non-Insulin-Dependent, Polyneuropathy, Ulcer | Altered Intercellular Communication | Prospective studies should establish whether the pronounced reduction of cutaneous LCs detected in recently diagnosed type 2 diabetes could promote a cutaneous immunogenic imbalance toward inflammation predisposing to polyneuropathy and foot ulcers. | 24319115 |
| Inflammation, Chronic Kidney Diseases | Altered Intercellular Communication | Chronic kidney disease (CKD) is associated with inflammation. | 24321183 |
| Inflammation, Chronic Kidney Diseases | Altered Intercellular Communication | CKD patients with inflammation treated with atorvastatin had significantly less eGFR decline. | 24321183 |
| Inflammation, SERPINB3 wt Allele | Altered Intercellular Communication | CPA is a common disease and the monitoring as well as the treatment of such a chronic oral inflammation may be beneficial in reducing one potential cause of OSCC. | 24321243 |
| Inflammation, Traumatic injury, Intraosseous Route of Drug Administration | Altered Intercellular Communication | The origin of this lesion is uncertain; however, factors such as local trauma, inflammation, intraosseous hemorrhage, and genetic abnormalities have been identified as possible causes. | 24321310 |
| Inflammation, Granuloma | Altered Intercellular Communication | The cavity wall showed chronic inflammation and occasional giant cells but no granulomas and no microorganisms. | 24321524 |
| Inflammation, Fibrosis Assessment, Fatty degeneration, Non-alcoholic Fatty Liver Disease, Balloon Dilatation | Altered Intercellular Communication | Although there were no differences between groups in the histological severity of steatosis, inflammation, ballooning degeneration, NAFLD activity score, or histological grade, subjects with OSA/hypoxemia had significantly more severe hepatic fibrosis. | 24321532 |
| Steatohepatitis, Non-alcoholic Fatty Liver Disease | Altered Intercellular Communication | Increasing percentage of time with oxygen saturation <=90% was related to NAFLD inflammation grade (r = 0.44; P = .03), degree of hepatic steatosis (r = -0.50; P = .01), NAFLD activity score (r = 0.42; P = .04), aspartate aminotransferase level (r = 0.56; P = .004), and alanine aminotransferase level (r = 0.44; P = .03). | 24321532 |
| Familial spinal arachnoiditis, Inflammation | Altered Intercellular Communication | Spinal arachnoiditis is a disease characterized by inflammation and scarring of the arachnoid membrane of the spinal cord. | 24321827 |
| Inflammation, Hyperplasia | Altered Intercellular Communication | All along the treatment and after it, the hyperplasia and the gingival inflammation not only maintained but they even got worse. | 24322040 |
| Sarcoidosis, Inflammatory abnormality of the eye | Altered Intercellular Communication | Therefore, sarcoidosis should be kept in mind when evaluating a patient with ocular inflammation. | 24322273 |
| Fibrous, Inflammation | Altered Intercellular Communication | Pathological examination of thoracoscopic biopsy specimen showed fibrous tissue with mild inflammation and no malignant feature. | 24322358 |
| Inflammation | Altered Intercellular Communication | Based on our findings, we postulate that age-associated biochemical changes may accentuate the inflammation associated with OAB. | 24323058 |
| Prostate carcinoma, prostatitis | Altered Intercellular Communication | Baseline prostate inflammation is associated with a reduced risk of prostate cancer in men undergoing repeat prostate biopsy: results from the REDUCE study. | 24323568 |
| Prostate carcinoma, prostatitis, Structure of posterior cerebral artery | Altered Intercellular Communication | The current study was performed to evaluate whether baseline acute and chronic prostate inflammation among men with an initial negative biopsy for prostate cancer (PCa) increased the risk of subsequent PCa detection in a clinical trial with systematic biopsies. | 24323568 |
| Structure of posterior cerebral artery, prostatitis | Altered Intercellular Communication | PCa, acute prostate inflammation, and chronic prostate inflammation were assessed by central review. | 24323568 |
| Inflammation | Altered Intercellular Communication | Acute and chronic inflammation and both were detected in 46 baseline biopsies (1%), 3931 baseline biopsies (63%), and 892 baseline biopsies (14%), respectively. | 24323568 |
| Inflammation | Altered Intercellular Communication | Acute and chronic inflammation were found to be significantly associated with each other (P<.001). | 24323568 |
| Inflammation | Altered Intercellular Communication | Baseline acute and chronic inflammation were both found to be independently associated with a lower PCa risk. | 24323568 |
| Inflammation, Structure of posterior cerebral artery | Altered Intercellular Communication | From a clinical standpoint, inflammation in negative biopsies for PCa may lower the risk of subsequent PCa detection. | 24323568 |
| Degenerative polyarthritis, Inflammation, Obesity | Altered Intercellular Communication | The decrease in CRP levels in patients with SAP, combined with OA and obesity with concomitant therapy by the proposed method, indicates a decrease in systemic inflammation. | 24323963 |
| ARCN1 gene, Inflammation, Cardiovascular Diseases, Chronic Obstructive Airway Disease, physiopathological | Altered Intercellular Communication | Chronic obstructive pulmonary disease (COPD) is characterized by low pulmonary function, inflammation, free radical production, vascular dysfunction, and subsequently a greater incidence of cardiovascular disease. | 24324045 |
| Colorectal Carcinoma, Primary Neoplasm | Altered Intercellular Communication | Prognostic value of preoperative inflammation-based prognostic scores in patients with stage IV colorectal cancer who undergo palliative resection of asymptomatic primary tumors. | 24324099 |
| Autoimmune Diseases, Chronic lymphocytic inflammation | Altered Intercellular Communication | Primary SS is an autoimmune disease characterized by chronic lymphocytic inflammation and ectopic germinal centre (GC) formation within salivary glands. | 24324211 |
| Tissue damage, Inflammation, Endothelial dysfunction, Carotid Atherosclerosis | Altered Intercellular Communication | The preferential proinflammatory Th1 activation suggests that actin could contribute to endothelial dysfunction, tissue damage, and systemic inflammation in carotid atherosclerosis. | 24324294 |
| Inflammation, Prostate carcinoma, Benign prostatic hypertrophy | Altered Intercellular Communication | [Differences in pathological features of histological inflammation between benign prostatic hyperplasia and prostate cancer]. | 24325107 |
| Inflammation, Prostate carcinoma, Benign prostatic hypertrophy, Structure of posterior cerebral artery | Altered Intercellular Communication | To study the pathologic features and differences of tissue inflammation in benign prostatic hyperplasia (BPH) and prostate cancer (PCa). | 24325107 |
| Inflammation, Structure of posterior cerebral artery | Altered Intercellular Communication | The HE stained slice obtained by prostate biopsy from 143 BPH and 106 PCa were reviewed to determine whether the tissue inflammation existed. | 24325107 |
| Inflammation, Structure of posterior cerebral artery | Altered Intercellular Communication | There were 142 cases found tissue inflammation in 143 BPH patients and 104 cases in 106 PCa patients, so the incidences of tissue inflammation in BPH and PCa were 99. | 24325107 |
| Inflammation, Structure of posterior cerebral artery | Altered Intercellular Communication | The anatomical location of inflammation was significant difference between BPH and PCa group (P<0. | 24325107 |
| Interstitial inflammation | Altered Intercellular Communication | 3%) was primary in BPH, and interstitial inflammation (56.7%) was the main pattern in PCa. | 24325107 |
| Inflammation, Structure of posterior cerebral artery | Altered Intercellular Communication | The incidences of tissue inflammation were high in both BPH and PCa, but the pathological features of tissue inflammation were different between BPH and PCa. | 24325107 |
| Inflammation, Thrombosis, Systemic Inflammatory Response Syndrome, Leukocytosis | Altered Intercellular Communication | Although inflammation is considered a risk factor for deep vein thrombosis, the prognostic significance of both systemic inflammatory response syndrome (SIRS) and leukocytosis has not been elucidated. | 24325351 |
| Inflammation, Edema, Ischemia | Altered Intercellular Communication | Inflammation and/or ischemia may increase vascular permeability and disrupt the blood-aqueous barrier by increasing levels of inflammatory factors in patients with CRVO and macular edema. | 24325604 |
| Inflammation, Metabolic Syndrome X | Altered Intercellular Communication | The human gut microbiota and microbial influences on lipid and glucose metabolism, satiety, and chronic low-grade inflammation are known to be involved in metabolic syndrome. | 24325907 |
| Inflammation, Diabetes Mellitus | Altered Intercellular Communication | Several studies show that high serum C-reactive protein (CRP) levels are associated with an increased risk of diabetes, data that strongly supports a possible role for inflammation in diabetogenesis. | 24326321 |
| Inflammation, Carcinogenesis, Pancreatic carcinoma | Altered Intercellular Communication | Inflammation has been implicated in carcinogenesis and progression of pancreatic cancer. | 24326841 |
| Inflammation, Dental Plaque | Altered Intercellular Communication | The plaque composition, cellularity, severity of inflammation, and atheroma-associated macrophages and foam cells were compared with virtual histology. | 24326894 |
| Inflammation, Critical Illness | Altered Intercellular Communication | We investigated whether C-reactive protein (CRP) as indicator of acute inflammation is associated with maximal isometric handgrip strength in non-critically ill patients. | 24327120 |
| Inflammation, Granuloma, Retinal Detachment, Parasitic cyst, Retinal fibrosis | Altered Intercellular Communication | The eye examination in the hospital showed damage of the left eye, red eye, retinal fibrosis, retinal detachment, inflammation of the eye tissues, retinal granulomas, and a parasitic cyst inside. | 24327783 |
| Necrotizing granulomatous inflammation, Coagulative necrosis, Fibrous | Altered Intercellular Communication | Pathologically, chronic granulomatous inflammation composed of coagulation necrosis with rim of fibrous tissues and granulations was seen. | 24327784 |
| Inflammation | Altered Intercellular Communication | The profiles of mesenteric and pancreatic lymph nodes differ and often change reciprocally due to directed migration of T cells towards the site of inflammation. | 24328490 |
| Inflammation, Insulitis, Infiltration | Altered Intercellular Communication | CD25(-)FoxP3(+) Treg are markedly increased in the pancreatic infiltrates in late stages of inflammation, possibly an effort to counteract destructive insulitis. | 24328490 |
| Inflammation, Liver damage, Fatty degeneration | Altered Intercellular Communication | Mice were sacrificed after 3 weeks, and steatosis, inflammation, apoptosis, and liver damage were assessed. | 24329600 |
| Inflammation, Fatty degeneration | Altered Intercellular Communication | CHOP deficiency did not affect steatosis but significantly reduced apoptotic cells, inflammation scores, and serum liver enzymes. | 24329600 |
| Inflammation, Injury of liver, Steatohepatitis, Fibrosis Assessment, Carcinogenesis | Altered Intercellular Communication | CHOP deficiency attenuated apoptosis, inflammation, fibrosis, and tumorigenesis under fat-loading conditions, indicating that a therapeutic strategy targeting CHOP might be effective for fat-induced liver injury and protecting against promotion of carcinogenesis in patients with liver steatosis. | 24329600 |
| Inflammation, Hypertensive (finding), Albuminuria | Altered Intercellular Communication | sRAGE may play a role in the pathogenic processes that link albuminuria, chronic inflammation and oxidative stress in hypertensive patients. | 24329736 |
| Inflammation, Paresis, Myelitis, Transverse, Bladder Sphincter Dysfunction | Altered Intercellular Communication | Transverse myelitis (TM) is the inflammation of the spinal cord characterized by rapidly evolving muscle weakness in the lower extremities, defects in sensory level and sphincter dysfunction. | 24330286 |
| Inflammation | Altered Intercellular Communication | Altered expression profiling in SpA and AS samples demonstrates that disease pathogenesis is associated with both systemic inflammation as well as local tissue alterations that may underlie tissue damaging modelling and remodelling outcomes. | 24330574 |
| Inflammation, Spondylarthropathies | Altered Intercellular Communication | This supports the hypothesis that initial systemic inflammation in spondyloarthropathies transfers to and persists in the local joint environment, and might subsequently mediate changes in genes directly involved in the destructive tissue remodelling. | 24330574 |
| Communicable Diseases, Inflammation, Comorbidity | Altered Intercellular Communication | A prospective study: inflammation, infection and comorbidity in patients on long-term dialysis. | 24330609 |
| HD Term Type, Inflammation, Cerebrovascular accident | Altered Intercellular Communication | Age, CVD and CVA are predictors for mortality in patients on HD patients, but the presence of C. pneumoniae IgG and inflammation are not. | 24330609 |
| Inflammation, Malignant Neoplasms | Altered Intercellular Communication | The NF-kB family of transcription factors is up-regulated in inflammation and different cancers. | 24330732 |
| Inflammation, Gangrene, Perforation (observation), Hernia | Altered Intercellular Communication | The diagnosis is always mistaken for the one of incarcerated or strangled hernia, the correct diagnosis being established intraoperatively, occasion which exposes the cecal appendix by opening the herniary bag, found in different morphological stages of inflammation that can go as far as gangrene or even perforation. | 24331333 |
| Inflammation, Benign prostatic hypertrophy | Altered Intercellular Communication | Inflammation plays a key role in the development of benign prostatic hyperplasia. | 24331343 |
| Inflammation, Inflammatory pain | Altered Intercellular Communication | Prostaglandin E2 (PGE2) is an important inflammation factor found in enlarged prostatic tissue that can be the main cause of inflammatory pain. | 24331343 |
| Airway structure, Asthma | Altered Intercellular Communication | The process of airway inflammation in the lungs of nonsmokers who die of asthma (fatal asthma) has not been reported in detail. | 24331389 |
| Inflammation, Periodontitis, diabetic | Altered Intercellular Communication | Chronic inflammation of periodontitis aggravates glycemic control in type 2 diabetic patients through aggravation of insulin resistance. | 24331774 |
| Inflammation, Radicular Cyst | Altered Intercellular Communication | Several cytokines participate in the mechanisms of inflammation, tissue repair, and bone resorption associated with periapical cysts. | 24331993 |
| Inflammation | Altered Intercellular Communication | Mean number of mast cells on the superficial region of the fibrous capsule was higher in cysts showing intense superficial inflammation and exocytosis. | 24331993 |
| Inflammatory abnormality of the eye, Uveitis | Altered Intercellular Communication | Eyes with uveitis, seen at 5 academic ocular inflammation centers in the United States, for which ME was documented to be currently present and the principal cause of reduced visual acuity (<20/40). | 24332536 |
| Inflammation, Damage | Altered Intercellular Communication | Evidence of significant ocular damage from inflammation (posterior synechiae and hypotony) portends a lower incidence of visual recovery. | 24332536 |
| Inflammation | Altered Intercellular Communication | Cancer-associated inflammation is increasingly recognised to be an important determinant of oncological outcome. | 24332571 |
| Cataract, Inflammation | Altered Intercellular Communication | To analyze the cause of fibrinous inflammation in eyes with capsular tension rings (CTRs) after cataract surgery. | 24333013 |
| Airway structure, Asthma | Altered Intercellular Communication | Patients with refractory asthma frequently have neutrophilic airway inflammation and respond poorly to inhaled corticosteroids. | 24333186 |
| Inflammation, Fibrosis Assessment, Nephrolithiasis | Altered Intercellular Communication | S100A8 and fibronectin, representatives of inflammation and fibrosis, respectively, were up-regulated in nephrolithiasis renal tissues. | 24333391 |
| Inflammation, Fibrosis Assessment, Kidney Calculi | Altered Intercellular Communication | Therefore, inflammation and fibrosis are suggested to be involved in the formation of kidney calculi. | 24333391 |
| Angina, Unstable, Arteritis | Altered Intercellular Communication | Plasma pentraxin 3 (PTX3) levels are increased in patients with arterial inflammation and especially unstable angina pectoris (UAP). | 24333560 |
| Inflammation | Altered Intercellular Communication | Four of them showed acute inflammation in the gallbladder while pathological signs of chronic inflammation in the gallbladder wall were detected in eight cases. | 24333981 |
| Inflammation | Altered Intercellular Communication | Fcg receptor upregulation is associated with immune complex inflammation in the mouse retina and early age-related macular degeneration. | 24334446 |
| methyldopa, Inflammation | Altered Intercellular Communication | Several lines of evidence suggest the involvement of antibodies and immune complex inflammation in AMD, a blinding disease with a strong inflammatory component. | 24334446 |
| methyldopa, Inflammation, Retinitis | Altered Intercellular Communication | To examine this further, we developed a novel experimental mouse model of retinal inflammation and evaluated whether inflammation associated with immune complex formation was present in eyes of AMD donors. | 24334446 |
| Inflammation | Altered Intercellular Communication | Colonoscopy showed inflammation of the descending colon and histopathology revealed patchy increase in intraepithelial lymphocytes. | 24334470 |
| Refractory anemias, Inflammation, Rheumatoid Arthritis, Disease | Altered Intercellular Communication | To assess the predictive value of magnetic resonance imaging (MRI)-detected subclinical inflammation for subsequent radiographic progression in a longitudinal study of patients with rheumatoid arthritis (RA) in clinical remission or low disease activity (LDA), and to determine cutoffs for an MRI inflammatory activity acceptable state in RA in which radiographic progression rarely occurs. | 24334647 |
| Inflammation, Rheumatoid Arthritis | Altered Intercellular Communication | Inflammation and disease activity are associated with high circulating cardiac markers in rheumatoid arthritis independently of traditional cardiovascular risk factors. | 24334650 |
| Inflammation | Altered Intercellular Communication | The association between HS-cTnT, NT-proBNP, and CRP, together with the correlation between HS-cTnT and disease activity, support the link between myocardial injury/dysfunction and inflammation. | 24334650 |
| Inflammatory abnormality of the eye | Altered Intercellular Communication | The patients with VKH disease were treated with high-dose systemic corticosteroids, which were tapered off gradually over a period of 6 months or more by the treating ophthalmologists according to the severity of the ocular inflammation. | 24335059 |
| Inflammation | Altered Intercellular Communication | In conclusion, as an inexpensive, simple, and accessible marker of inflammation, the NLR may be useful in predicting the presence and severity of MS in patients with RMVD. | 24335245 |
| Inflammation, Arthritis | Altered Intercellular Communication | Concordance between inflammation at physical examination and on MRI in patients with early arthritis. | 24336009 |
| Refractory anemias, Inflammation, Rheumatoid Arthritis | Altered Intercellular Communication | MRI is increasingly used to measure inflammation in rheumatoid arthritis (RA) research, but the correlation to clinical assessment is unexplored. | 24336009 |
| Inflammation, Joints | Altered Intercellular Communication | This study determined the association and concordance between inflammation of small joints measured with MRI and physical examination. | 24336009 |
| Inflammation | Altered Intercellular Communication | The MRI data were first analysed continuously and then dichotomised to analyse the concordance with inflammation at joint examination. | 24336009 |
| Inflammation, Wrist joint | Altered Intercellular Communication | In 86% of the swollen MCP joints and in 92% of the swollen wrist joints any inflammation on MRI was present. | 24336009 |
| Inflammation | Altered Intercellular Communication | In 27% of the non-swollen MCP joints and in 66% of the non-swollen wrist joints any MRI inflammation was present. | 24336009 |
| Inflammation, MTTP wt Allele | Altered Intercellular Communication | Vice versa, of all MCP, wrist and MTP joints with inflammation on MRI 64%, 61% and 77%, respectively, were not swollen. | 24336009 |
| Inflammation | Altered Intercellular Communication | Inflammation on MRI is not only present in clinically swollen but also in non-swollen joints. | 24336009 |
| Inflammation | Altered Intercellular Communication | Chronic inflammation is frequently associated with tumorigenesis in elderly people. | 24336323 |
| Inflammation, Neoplasms | Altered Intercellular Communication | By contrast, young people without chronic inflammation often develop tumors considered independent of chronic inflammation but driven instead by mutations. | 24336323 |
| Inflammation, Neoplasms | Altered Intercellular Communication | Thus, whether inflammation has a significant role in tumor progression in tumors driven by mutations remains largely unknown. | 24336323 |
| Acute Coronary Syndrome, Inflammation, Platelet aggregation test result | Altered Intercellular Communication | MKC improved the prognosis of patients with acute coronary syndrome, possibly through inhibiting the platelet aggregation, fighting against inflammation, and protecting the vascular endothelial function. | 24338186 |
| Inflammation, Tuberculosis, Necrosis, Necrotizing granulomatous inflammation, Tuberculosis, Laryngeal, Caseous necrosis | Altered Intercellular Communication | We studied 19 cases of laryngeal tuberculosis with typical histopathology (chronic granulomatous inflammation with caseous necrosis and langhans-type giant cells) and 6 cases of laryngeal tuberculosis with atypical histopathology (chronic granulomatous inflammation or chronic inflammation without necrosis). | 24338196 |
| Inflammation, Malignant Neoplasms, Tuberculosis | Altered Intercellular Communication | The primary clinical diagnosis was malignancy in 17 cases, tuberculosis in 5 cases, and nonspecific inflammation in 3 cases. | 24338196 |
| Inflammation, Fibrosis Assessment, Heart failure | Altered Intercellular Communication | Galectin-3, a biomarker associated with fibrosis and inflammation, has been implicated in development and progression of heart failure (HF) and predicts increased mortality and morbidity in this condition. | 24338533 |
| Inflammation, Fibrosis Assessment, Ulcerative Colitis, Crohn Disease | Altered Intercellular Communication | We studied the involvement of IL-13 in inflammation and fibrosis in UC and Crohn's disease (CD). | 24338958 |
| Inflammation | Altered Intercellular Communication | Hispanics had significantly lower SES, greater inflammation, as well as higher tender and swollen joint counts. | 24339449 |
| methyldopa, Inflammation | Altered Intercellular Communication | The present research supports the role of oxidative stress and inflammation in AMD and highlights the role of therapy directed against these risk factors. | 24340512 |
| Inflammation | Altered Intercellular Communication | The patient with p22 defect was diagnosed at two months of age; and gastric wall granuloma, inflammation in proximal femur was detected. | 24341149 |
| Inflammation, "Alzheimers Disease", Impaired cognition | Altered Intercellular Communication | Inflammation plays a crucial role in the pathophysiology of Alzheimer's disease and cognitive impairment. | 24342014 |
| Inflammation, Diabetes Mellitus, Non-Insulin-Dependent, Obesity | Altered Intercellular Communication | Obesity is frequently associated with low-grade inflammation of adipose tissue (AT), and the increase in adipose tissue macrophages (ATMs) is linked to an increased risk of type 2 diabetes. | 24343232 |
| Inflammation, Malaria, Intradermal Route of Drug Administration | Altered Intercellular Communication | Hemoglobin, iron deficiency (ID), vitamin A deficiency (VAD), inflammation, malaria, anthropometry, and STH ova were measured. | 24343884 |
| Perifolliculitis | Altered Intercellular Communication | The prevalence of trachomatous inflammation-follicular in children aged 1-9 years ranged from 0.3% in Sokoto South to 15.6% in Kalgo LGA. | 24344228 |
| Inflammation, Hemorrhage | Altered Intercellular Communication | These presentations result either from peritoneal inflammation and subsequent peritoneal bleeding or retroperitoneal cavity pathology rupturing into the peritoneal cavity. | 24344496 |
| Inflammation | Altered Intercellular Communication | On microscopy he had multiple foci of acute and chronic inflammation. | 24344506 |
| Orthodontic, Gingivitis, Dental Plaque | Altered Intercellular Communication | Orthodontic appliances can promote accumulation of dental plaque, with associated enamel decalcification or gingival inflammation. | 24345204 |
| Ulcerative Colitis, Inflammatory disease of mucous membrane | Altered Intercellular Communication | Compared with HC, the mucin chemotype in UC was less sulphated and inversely correlated with the degree of mucosal inflammation. | 24345279 |
| Inflammatory disease of mucous membrane | Altered Intercellular Communication | Mucin composition strongly correlates with the degree of mucosal inflammation, and to a lesser extent with DSV burden. | 24345279 |
| Inflammation, Ulcerative Colitis | Altered Intercellular Communication | Decreased sulphation of mucins has been associated with inflammation in ulcerative colitis. | 24345279 |
| Moorens ulcer", Ulcerative inflammation | Altered Intercellular Communication | Mooren's ulcer is a severe ulcerative inflammation of the cornea. | 24345289 |
| Gastrointestinal inflammation | Altered Intercellular Communication | The involvement of NOPs in the pathophysiology of GI inflammation has been suggested, but due to the lack of selective NOP agonists, it never fully elucidated. | 24345466 |
| Cataract, Pain Distress Question, Inflammatory abnormality of the eye | Altered Intercellular Communication | Once-daily nepafenac ophthalmic suspension 0.3% to prevent and treat ocular inflammation and pain after cataract surgery: phase 3 study. | 24345529 |
| Cataract, Eye pain, Inflammation | Altered Intercellular Communication | To evaluate once-daily nepafenac 0.3% to prevent and treat ocular pain and inflammation after cataract surgery. | 24345529 |
| Inflammation | Altered Intercellular Communication | The primary endpoint was the percentage of patients with a cure for inflammation (score of 0 for both aqueous cells and flare) at day 14. | 24345529 |
| Inflammation, Pain Distress Question | Altered Intercellular Communication | Significantly more nepafenac 0.3% patients had no inflammation (68.4% versus 34.0%) and were pain free (91.0% versus 49.7%) at day 14 than vehicle patients (both P<.0001). | 24345529 |
| Cataract, Pain Distress Question, Inflammatory abnormality of the eye | Altered Intercellular Communication | Once-daily nepafenac 0.3% was noninferior to nepafenac 0.1% 3 times daily for prevention and treatment of ocular inflammation and pain following cataract surgery. | 24345529 |
| Inflammation, Appendicitis, CTCAE, Perforation (observation), Necrosis | Altered Intercellular Communication | Emergency surgery is performed on patients with appendicitis in the belief that inflammation of the appendix may progress to necrosis and perforation. | 24345979 |
| Inflammation, Appendicitis, CTCAE | Altered Intercellular Communication | Many cases of appendicitis, however, resolve with conservative treatment, and necrotic appendicitis may represent a different disease rather than the end result of inflammation of the appendix. | 24345979 |
| Inflammation, Necrosis | Altered Intercellular Communication | In addition, our findings add weight to the increasing volume of data showing that necrosis of the appendix is a disease different from simple inflammation. | 24345979 |
| Inflammation, Acne Vulgaris, Acne fulminans | Altered Intercellular Communication | We present the case of a 18-year-old male patient in whom acne fulminans evolved from acne vulgaris grade IV and after inflammation resolution started treatment with oral isotretinoin. | 24346917 |
| Inflammation, Observation Method - Coagulation, Primary malignant neoplasm | Altered Intercellular Communication | Increasing evidence indicates the involvement of inflammation and coagulation in cancer progression and metastases. | 24347236 |
| Inflammation | Altered Intercellular Communication | Children who are burned >40% total body surface area lose significant quantities of both bone and muscle mass because of acute bone resorption, inflammation, and endogenous glucocorticoid production, which result in negative nitrogen balance. | 24347438 |
| Inflammation, Dyslipidemias, Atherosclerosis | Altered Intercellular Communication | Chronic hemodialysis patients experience accelerated atherosclerosis contributed to by dyslipidemia, inflammation, and an impaired antioxidant system. | 24348043 |
| Inflammation, Gland, Infection caused by Helicobacter pylori | Altered Intercellular Communication | Chronic inflammation, neutrophil activity and glandular atrophy showed statistically significant association with H. pylori infection. | 24349327 |
| Inflammation, Metabolic acidosis | Altered Intercellular Communication | This relationship between low bicarbonate levels and adverse outcome could be related to enhanced inflammation and a more rapid loss of RRF associated with metabolic acidosis. | 24349396 |
| Communicable Diseases, Additional, Inflammation | Altered Intercellular Communication | Additional sepsis biomarkers do not aid in discriminating inflammation from infection. | 24349403 |
| Inflammation, Protein-Energy Malnutrition | Altered Intercellular Communication | Inflammation but not dietary macronutrients insufficiency associated with the malnutrition-inflammation score in hemodialysis population. | 24349471 |
| Inflammation, Malnutrition, Protein-Energy Malnutrition | Altered Intercellular Communication | In conclusion, malnutrition is very common in South China hemodialysis population and these data indicated that inflammation but not dietary macronutrients insufficiency might be the candidate cause for malnutrition in hemodialysis population. | 24349471 |
| Inflammation, Cerebral Small Vessel Diseases | Altered Intercellular Communication | This study was designed to explore the relationship between low-grade inflammation and renal microangiopathy in T2DM. | 24350298 |
| Inflammation, Edema | Altered Intercellular Communication | It has been hypothesized that inflammation and edema in the surgery site has a major role in voice change after thyroidectomy. | 24351352 |
| Inflammation, Cardiac Death, Atherosclerosis | Altered Intercellular Communication | All of these foods and nutrients may affect cholesterol, inflammation, the development of atherosclerosis, and, therefore, risk of cardiac death. | 24351877 |
| Carcinogenesis, Acute and chronic inflammation, Primary malignant neoplasm | Altered Intercellular Communication | Recently, it was reported that gene editing enzyme, activation-induced cytidine deaminase (AID), is expressed in precursor and cancer epithelial cells during carcinogenesis associated with chronic inflammation/infection and that this enzyme induces mutation of tumor-suppressor genes. | 24351917 |
| Inflammation | Altered Intercellular Communication | The leukocyte architecture observed in normal skin was distorted in inflammation and disease. | 24352044 |
| Inflammation | Altered Intercellular Communication | Advantages deriving from early control of joint inflammation may explain the maintenance of results at follow-up. | 24352823 |
| Inflammation, Fibrosis Assessment | Altered Intercellular Communication | Lymphatic dysregulation leads to inflammation, scarring, and fibrosis, but inadvertent injection of these vessels can be avoided with anatomical knowledge. | 24353247 |
| ARTERIAL TORTUOSITY SYNDROME, Inflammation, Hemorrhage, Atherosclerosis, Dental Plaque | Altered Intercellular Communication | Plaque hemorrhage, inflammation and microvessel density are key determinants of plaque vulnerability in native coronary atherosclerosis (ATS). | 24354875 |
| Inflammation, CAV1 gene | Altered Intercellular Communication | This study investigates the role of intraplaque hemorrhage (IPH) and its relation with inflammation and microvessels in cardiac allograft vasculopathy (CAV) in posttransplanted patients. | 24354875 |
| Inflammation | Altered Intercellular Communication | Intralesion inflammation, microvessels and IPH were assessed semi-quantitatively. | 24354875 |
| Inflammation, CAV1 gene | Altered Intercellular Communication | Inflammation was present in 31/35 (88.6%) of CAV lesions. | 24354875 |
| Inflammation, CAV1 gene, Microvessels | Altered Intercellular Communication | IPH, associated with microvessel damage and inflammation, is an important feature of CAV. | 24354875 |
| Inflammation, Rheumatoid Arthritis | Altered Intercellular Communication | Relationship between inflammation and infliximab pharmacokinetics in rheumatoid arthritis. | 24354889 |
| Refractory anemias, Inflammation | Altered Intercellular Communication | The influence of methotrexate and inflammation on infliximab clearance suggests that individual adjustment of infliximab doses according to disease activity may be useful in RA. | 24354889 |
| Inflammation | Altered Intercellular Communication | The clinical and histopathological findings of our reported case lend support to the possible role of inflammation in the pathogenesis of HH/HHE syndrome. | 24355077 |
| Inflammation, Obesity | Altered Intercellular Communication | Benefit of physical fitness against inflammation in obesity: role of beta adrenergic receptors. | 24355098 |
| Inflammation, Inflammatory disorder, Obesity | Altered Intercellular Communication | Evidence shows that both poor physical fitness and obesity are linked to low-grade inflammation and inflammatory diseases. | 24355098 |
| Inflammation | Altered Intercellular Communication | However, their relative roles on inflammation and underlying mechanisms remain unclear. | 24355098 |
| Inflammation, Overweight, Obesity | Altered Intercellular Communication | We examined circulating levels of inflammatory cytokines TNF, IL-1b, IL-6 and b-AR sensitivity of, 70 overweight or obese compared to 26 normal-weight, otherwise healthy individuals in order to investigate the associations among obesity, physical fitness, and low-grade inflammation and to examine the role of b-ARs in these relationships. | 24355098 |
| Inflammation, Diabetes Mellitus | Altered Intercellular Communication | Age, diabetes, and inflammation together explained the inverse association between HRV and PWV. | 24356038 |
| Inflammation | Altered Intercellular Communication | Inflammation may play a role in the pathogenesis of both low HRV and high PWV. | 24356038 |
| Inflammation, Cerebrovascular accident | Altered Intercellular Communication | Inflammation plays a crucial role in the pathogenesis and prognosis of stroke. | 24356104 |
| Inflammation, Chronic Kidney Diseases | Altered Intercellular Communication | Our data support the view that there is increased inflammation in CKD and DN. | 24356550 |
| Inflammation, hepcidin | Altered Intercellular Communication | Further studies should examine whether increased weight contributes towards hepcidin elevation in predialysis individuals, in whom there is a lesser burden of systemic inflammation. | 24356769 |
| Hernia of abdominal cavity, Inflammation | Altered Intercellular Communication | Prevalence of systemic inflammation and micronutrient imbalance in patients with complex abdominal hernias. | 24356980 |
| Hernia of abdominal cavity, Inflammation | Altered Intercellular Communication | To determine the prevalence of low-grade inflammation, micronutrient imbalances and associated clinical profiles in patients being evaluated for complex abdominal hernia repair. | 24356980 |
| Inflammation, Protein-Energy Malnutrition | Altered Intercellular Communication | In this comorbidity-rich population with known variability in surgical outcomes, the prevalence of chronic inflammation and micronutrient deficiency are high enough to warrant systemic preoperative evaluation given their possible effect on wound healing and convalescence. | 24356980 |
| Inflammatory, Inflammation | Altered Intercellular Communication | The correlation between the presence of leukocytes in the CSF of patients suffering from MS and the number of inflammatory lesions as detected by magnetic resonance imaging suggests that inflammation at the choroid plexus contributes to the disease, although in a yet unknown fashion. | 24356983 |
| Barrett Esophagus, Inflammation | Altered Intercellular Communication | Cyclooxygenase-2 and inflammation mediators have a crucial role in reflux-related esophageal histological changes and Barrett's esophagus. | 24357184 |
| Inflammation, Anemia, hepcidin | Altered Intercellular Communication | A mouse model of anemia of inflammation: complex pathogenesis with partial dependence on hepcidin. | 24357728 |
| Inflammatory, Inflammation, Anemia, hepcidin | Altered Intercellular Communication | Similarly to severe human anemia of inflammation, the B abortus model shows multifactorial pathogenesis of inflammatory anemia including iron restriction from increased hepcidin, transient suppression of erythropoiesis, and shortened erythrocyte lifespan. | 24357728 |
| Inflammation, Primary malignant neoplasm | Altered Intercellular Communication | With growing evidence on the role of inflammation in cancer biology, the systemic inflammatory response has been postulated as having prognostic significance in a wide range of different cancer types. | 24357794 |
| Inflammation, Primary malignant neoplasm | Altered Intercellular Communication | Inflammation has a critical role in the pathogenesis and progression of cancer. | 24357796 |
| Airway structure | Altered Intercellular Communication | Pro-resolution mediator lipoxin A4 and its receptor in upper airway inflammation. | 24358628 |
| Inflammation | Altered Intercellular Communication | The resolution of inflammation is an active process controlled by several anti-inflammatory and pro-resolution mediators. | 24358628 |
| Inflammation | Altered Intercellular Communication | Lipoxin A4, an endogenous lipid mediator, is a potential pro-resolution mediator that could attenuate inflammation. | 24358628 |
| Airway structure | Altered Intercellular Communication | This study was conducted to elucidate the role of lipoxin A4 in upper airway inflammation. | 24358628 |
| Airway structure | Altered Intercellular Communication | These results indicate that lipoxin A4 may play a role in the resolution of upper airway inflammation. | 24358628 |
| palladium, Inflammation | Altered Intercellular Communication | In addition, sites with inflammation and PD >=5 mm had significantly greater odds of exhibiting Fas, sFasL, and caspase-3 expression compared with sites without inflammation and PD <5 mm (P <0.05). | 24359166 |
| Inflammation | Altered Intercellular Communication | The inter-relation between Ab, inflammation and cholinergic signaling is complex, with each feeding back onto the others to drive disease progression. | 24359497 |
| Conjunctivitis | Altered Intercellular Communication | We consider such treatment a very effective initial immunosuppressive alternative in patients with moderate conjunctival inflammation and in cases of rapid progression. | 24359845 |
| Nonalcoholic Steatohepatitis, Inflammation, Steatohepatitis, Fibrosis Assessment, Fatty degeneration, Non-alcoholic Fatty Liver Disease | Altered Intercellular Communication | Overall, 45% of the biopsy specimens analyzed had steatosis >=33%, 22% had grade >=2 lobular inflammation, 81% had portal inflammation, 29% had ballooned hepatocytes, 35% had "suspicious/borderline" steatohepatitis, 8% had definite nonalcoholic steatohepatitis, 34% had an NAFLD activity score >=4, and 46% had fibrosis (38% mild/moderate and 8% bridging/cirrhosis). | 24360992 |
| Inflammation, Fibrosis Assessment, Non-alcoholic Fatty Liver Disease, Fatty degeneration | Altered Intercellular Communication | Marked steatosis (50% vs 24%) and fibrosis (54% vs 12%) were significantly more common in the patients with mildly elevated ALT compared with those with normal ALT, with no difference in ballooning, inflammation, or NAFLD activity score >=4 between the 2 groups. | 24360992 |
| Inflammation, Dyslipidemias, Abdominal aortic calcification | Altered Intercellular Communication | Osteoprotegerin, inflammation and dyslipidemia are associated with abdominal aortic calcification in non-diabetic patients on peritoneal dialysis. | 24361071 |
| Inflammation, Injury of pancreas | Altered Intercellular Communication | After pancreatic injury or inflammation, proteases such as trypsin activate the complement system and can potentially cause coagulation and leukoembolization of retinal precapillary arterioles. | 24362324 |
| Inflammation | Altered Intercellular Communication | Ineffectual antibody production with misdirected cytokine responses and excess inflammation in the airways are common to both groups. | 24362692 |
| Inflammation, Diabetic Retinopathy, Obesity, Disturbance, Diabetes Mellitus, Non-Insulin-Dependent | Altered Intercellular Communication | Inflammation, haemostatic disturbance, and obesity: possible link to pathogenesis of diabetic retinopathy in type 2 diabetes. | 24363502 |
| Diabetic Retinopathy, Inflammation, GDC Disease Response Terminology | Altered Intercellular Communication | The pathogenesis of diabetic retinopathy (DR) is insufficiently understood but may possibly involve chronic, low-grade inflammation. | 24363502 |
| Inflammation, Diabetic Retinopathy, Endothelial dysfunction, Obesity, Disturbance | Altered Intercellular Communication | Interrelations between obesity, inflammation, haemostatic disturbance, and other risk factors may possibly play an important additional role in endothelial dysfunction involved in the pathogenesis of diabetic retinopathy. | 24363502 |
| Crohn Disease | Altered Intercellular Communication | Role of the advanced glycation end products receptor in Crohn's disease inflammation. | 24363518 |
| Inflammation | Altered Intercellular Communication | RAGE is up-regulated in CD, especially in inflamed areas, and it appears to play a role in the mechanisms involved in chronic inflammation. | 24363518 |
| Inflammation, Liver cyst, Hemangioma, Infiltration | Altered Intercellular Communication | The remaining 46 nodules were benign (28 were of hepatocyte origin, nine were hepatic cysts, seven were hemangiomas, one was chronic inflammation, and one was focal fat infiltration). | 24363528 |
| Inflammation, Abdominal Abscess | Altered Intercellular Communication | She developed an intra-abdominal abscess around the remnant pancreas head 31 d after the surgery, and computed tomography (CT) showed an occluded portal vein due to the spreading inflammation around the abscess. | 24363537 |
| Inflammation, Left ventricular systolic dysfunction | Altered Intercellular Communication | Hemodialysis-induced regional left ventricular systolic dysfunction and inflammation: a cross-sectional study. | 24364893 |
| Inflammation, Endothelium, Global systolic dysfunction | Altered Intercellular Communication | We tested the hypothesis that hemodialysis-induced regional LV systolic dysfunction is associated with inflammation and endothelial injury. | 24364893 |
| Inflammation, Global systolic dysfunction | Altered Intercellular Communication | Intradialysis courses of markers of inflammation, bioincompatibility, and endothelial function did not differ in patients with versus without hemodialysis-induced regional LV systolic dysfunction. | 24364893 |
| Inflammation, Calcification of coronary artery, Atherosclerosis | Altered Intercellular Communication | Coronary angiography or computed tomography for quantification of coronary calcifications in our patients was not performed; therefore, we could not relate markers of inflammation to the extent of atherosclerosis. | 24364893 |
| Synovitis, Inflammation, Osteoarthritis, Knee | Altered Intercellular Communication | Degree of synovitis on MRI by comprehensive whole knee semi-quantitative scoring method correlates with histologic and macroscopic features of synovial tissue inflammation in knee osteoarthritis. | 24365722 |
| Inflammation, Synovitis | Altered Intercellular Communication | To evaluate the association between synovitis on contrast enhanced (CE) MRI with microscopic and macroscopic features of synovial tissue inflammation. | 24365722 |
| Inflammation, Anal Fistula | Altered Intercellular Communication | The patient had received operations for anal fistula and inflammation three times. | 24365737 |
| Inflammation | Altered Intercellular Communication | CRSwNP is characterized by significant elevations in circulating moDCs, which is associated with systemic Th2-biased inflammation. | 24367054 |
| Inflammatory disease of mucous membrane | Altered Intercellular Communication | Circulating moDCs are associated with mucosal inflammation on CT imaging in CRSsNP. | 24367054 |
| skin impairment, Inflammation, Diabetes Mellitus, Cardiovascular Diseases | Altered Intercellular Communication | We previously observed an association between these mutations and type 2 diabetes and hypothesized that an inherited impairment of skin barrier functions could facilitate low-grade inflammation and hence increase the risk of diabetes and cardiovascular disease. | 24367652 |
| Weight decreased, Inflammatory abnormality of the eye | Altered Intercellular Communication | While dynasore did not reduce ocular inflammation, it did provide significant protection against weight loss. | 24367704 |
| Multiple polyps, Inflammation, Ulcerative Colitis, Entrapment of Device, Stasis | Altered Intercellular Communication | Significantly, 7 of 10 cases with postoperative diagnoses of UC (70%) had Crohn's-like transmural inflammation exclusively within the polyposis segments attributed to fecal entrapment and stasis and accounting for the Crohn's-like clinical complications in these cases. | 24368253 |
| Inflammation, Fuchs Endothelial Dystrophy | Altered Intercellular Communication | Inflammation can be an etiologic factor of Fuchs' dystrophy according to previous studies. | 24368317 |
| Inflammation, Traumatic injury | Altered Intercellular Communication | Persistent inflammation, immunosuppression, and catabolism syndrome after severe blunt trauma. | 24368353 |
| Multiple Organ Failure, Inflammation | Altered Intercellular Communication | We recently proffered that a new syndrome persistent inflammation, immunosuppression, and catabolism syndrome (PICS) has replaced late multiple-organ failure as a predominant phenotype of chronic critical illness. | 24368353 |
| Inflammation, Traumatic injury | Altered Intercellular Communication | We performed a secondary analysis of the Inflammation and Host Response to Injury database of adults with severe blunt trauma. | 24368353 |
| Inflammation, Lung diseases | Altered Intercellular Communication | Bio-active trace metals have been identified in respiratory tract secretions of subjects with lung disease and may potentially influence bacterial virulence, inflammation and disease severity. | 24369896 |
| Inflammation, Necrosis | Altered Intercellular Communication | Elevated concentrations of sputum metal ions appear to be associated with cell/tissue necrosis and inflammation in subjects with CF and NCFB. | 24369896 |
| Communicable Diseases, Allergy - Charge Type Reason, Inflammation, Respiration Disorders | Altered Intercellular Communication | Non-invasive sampling of airway epithelial-lining-fluid by nasal lavage (NL) is an emerging method to monitor allergy, infection and inflammation in patients with respiratory diseases. | 24370751 |
| Chronic infectious disease, Inflammation | Altered Intercellular Communication | Influences of repeated NL, centrifugation setups, repeated freezing and thawing, and protease inhibitors on mediator concentration were evaluated in healthy controls and CF patients, which serve as a model for chronic bacterial infection and inflammation. | 24370751 |
| Cessation of life, Inflammation, Fibrosis Assessment, Chronic Kidney Diseases | Altered Intercellular Communication | Biomarkers of inflammation, fibrosis, cardiac stretch and injury predict death but not renal replacement therapy at 1 year in a Canadian chronic kidney disease cohort. | 24371297 |
| Inflammation, Fibrosis Assessment, Chronic Kidney Diseases | Altered Intercellular Communication | Newer biomarkers, reflective of biological processes, such as inflammation and fibrosis, cardiac stretch or damage and vascular health may be useful in understanding clinical events in chronic kidney disease (CKD). | 24371297 |
| Inflammation, Neoplasms | Altered Intercellular Communication | Interleukin-6 plays an important role in chronic inflammation as well as tumor growth and progression. | 24371367 |
| Inflammation, Lymphohistiocytosis, Hemophagocytic | Altered Intercellular Communication | Hemophagocytic lymphohistiocytosis (HLH) is a rare syndrome of extreme inflammation caused by pathologic activation of the immune system. | 24371860 |
| Inflammation, Lymphoma, Mucosa-Associated Lymphoid Tissue Lymphoma | Altered Intercellular Communication | Extranodal marginal zone lymphoma of mucosa-associated lymphoid tissue (MALT lymphoma) comprises 7-8% of B-cell lymphomas and commonly originates from a background of long-standing chronic inflammation. | 24372375 |
| Inflammation, Chronic Kidney Diseases | Altered Intercellular Communication | States of advanced chronic kidney disease and dialysis are associated with a state of chronic inflammation. | 24372974 |
| vascular inflammations, Endothelial dysfunction | Altered Intercellular Communication | The effect of aspirin upon platelet function is well documented although experimental studies suggest that aspirin may also affect oxidative stress, vascular inflammation, endothelial dysfunction and dysglycaemia. | 24372992 |
| Inflammation, Erosion lesion | Altered Intercellular Communication | The presence of signs of inflammation, bone erosions or rotator cuff pathology was evaluated. | 24373322 |
| ARCN1 gene, Inflammation, Inflammatory lung disease | Altered Intercellular Communication | YKL-40 is a potential biomarker of inflammation and mortality in patients suffering from inflammatory lung disease, but its prognostic value in patients with COPD remains unknown. | 24373580 |
| Inflammation, physiopathological | Altered Intercellular Communication | Exposure to particulate air pollution increases respiratory and cardiovascular morbidity and mortality, especially in elderly, possibly through inflammation and vascular dysfunction. | 24373585 |
| Inflammation, Atherosclerosis | Altered Intercellular Communication | Two main features are involved in the progression of atherosclerosis, lipid retention and inflammation. | 24373925 |
| Inflammation, Atherosclerosis | Altered Intercellular Communication | 12/15-lipoxygenases are involved in inflammation and have been implicated in atherosclerosis. | 24373925 |
| Inflammation, Acute Coronary Syndrome, Depression, CTCAE | Altered Intercellular Communication | Do platelet-derived microparticles play a role in depression, inflammation, and acute coronary syndrome? | 24374086 |
| Inflammation | Altered Intercellular Communication | Both abnormal platelet physiology and inflammation have been suggested as potential confounding variables. | 24374086 |
| Inflammation, Depression, CTCAE, GDC AJCC Clinical Stage Terminology | Altered Intercellular Communication | We set out to examine platelet activation, inflammation, and levels of depression in hospitalized patients presenting with ACS. | 24374086 |
| Inflammation, Depression, CTCAE, Thrombosis of blood vessel | Altered Intercellular Communication | These results are intriguing in that a potential pathway to explain the connection between depression, inflammation, and increased cardiovascular thrombosis might be found when both platelet activation and inflammation are measured. | 24374086 |
| Inflammatory Bowel Diseases, Inflammation | Altered Intercellular Communication | Fecal hemoglobin and calprotectin are equally effective in identifying patients with inflammatory bowel disease with active endoscopic inflammation. | 24374878 |
| Inflammatory Bowel Diseases, Inflammation | Altered Intercellular Communication | Fecal calprotectin can be used as a noninvasive tool to assess inflammation in patients with inflammatory bowel disease (IBD). | 24374878 |
| Inflammatory Bowel Diseases, Inflammation | Altered Intercellular Communication | We compared the efficacy of fecal hemoglobin and calprotectin as markers for endoscopic inflammation in patients with IBD. | 24374878 |
| Inflammatory Bowel Diseases, Inflammation | Altered Intercellular Communication | Fecal hemoglobin can identify patients with IBD with active inflammation with a predictive accuracy similar to calprotectin. | 24374878 |
| Inflammation, Carotid Atherosclerosis | Altered Intercellular Communication | Inflammation plays a role in the pathogenesis of carotid atherosclerosis. | 24375839 |
| Inflammation, Nucleolar Fibrillar Material, Congenital bilateral aplasia of vas deferens | Altered Intercellular Communication | While earlier studies demonstrated that alterations in fluid shear stress (FSS) on the fibrosa could trigger inflammation, the mechanisms of CAVD pathogenesis secondary to side-specific FSS abnormalities are poorly understood. | 24376809 |
| Polymyositis, Myositis, CTCAE 5.0, Myositis | Altered Intercellular Communication | Although not as common as polymyositis, inclusion body myositis (IBM) is a form of inflammatory myopathy characterized by chronic progressive muscle inflammation and often goes undiagnosed and untreated. | 24377075 |
| Inflammation, Fibromyalgia | Altered Intercellular Communication | Metal-induced inflammation triggers fibromyalgia in metal-allergic patients. | 24378456 |
| Inflammation, Federated States of Micronesia | Altered Intercellular Communication | This suggests that metal-induced inflammation might be an important risk factor in a subset of patients with FM. | 24378456 |
| Inflammation, Pericardial Effusion, CTCAE, Myocarditis, CTCAE 5.0 | Altered Intercellular Communication | The presence of pericardial effusion (PE) is considered to be suggestive of inflammation in suspected myocarditis. | 24378485 |
| Myocarditis, CTCAE 5.0, AMCN gene, Myocarditis | Altered Intercellular Communication | According to EMB results, PE was found in 86% of patients with AMC, 67% with chronic myocarditis, and 56% without evidence of myocardial inflammation. | 24378485 |
| Tissue damage, Inflammation, Inflammatory Bowel Diseases | Altered Intercellular Communication | Matrix metalloproteinases (MMPs), tissue inhibitors of metalloproteinases (TIMPs), a disintegrin and metalloprotease with thrombospondin motifs [ADAM(TS)s] and growth factors are involved in inflammation and tissue damage and repair, all occurring in inflammatory bowel disease (IBD). | 24378596 |
| Epithelial Damage, Inflammation | Altered Intercellular Communication | Our data suggest that suppression of inflammation results in the arrest of epithelial damage and subsequent mucosal healing. | 24378596 |
| Inflammation, Federated States of Micronesia | Altered Intercellular Communication | The Ex + PLA group showed significant changes in MMI (+0.33 kg/m, P <= 0.009) and FM compartments (waist circumference, -5.13 cm; % FM, -1.31%; P <= 0.001), whereas inflammation remained unchanged. | 24378766 |
| Psoriasis, Atrial Fibrillation by ECG Finding | Altered Intercellular Communication | Inflammation contributes to the pathogenesis of psoriasis as well as atrial fibrillation. | 24379001 |
| palladium, Inflammation | Altered Intercellular Communication | In the PD group more advanced age had a decisive negative impact on survival whereas in the HD group the outlook was dependent on factors related to nutrition and inflammation. | 24379248 |
| Inflammation | Altered Intercellular Communication | These findings support the current concept of chronic Th17-cell mediated inflammation and provide evidence that links the Th17 signatures to ocular-specific immune responses in BSCR. | 24379648 |
| Primary malignant neoplasm, Supraventricular Tachycardia by ECG Finding, Unknown (origin) (qualifier value), Abdominal Infection, Liver Cirrhosis | Altered Intercellular Communication | Most common risk factors included cirrhosis (27.8%), solid cancer (22.3%), and intra-abdominal inflammation/infection (11.7%); in 27.4% of patients, SVT was idiopathic. | 24381147 |
| vascular inflammations, Restenosis | Altered Intercellular Communication | Greater vascular inflammation after ELA with spot stent resulted in earlier restenosis and inferior 1-year clinical outcomes than primary stenting. | 24381515 |
| Gingivitis, Ulcer, Calculi, Tooth structure, Dental Plaque, Alveolar Bone Loss | Altered Intercellular Communication | The clinical examination also showed that there were no statistically significant differences with respect to ulcerations, gingival recession, tooth mobility, gingival inflammation, periodontal bone loss, DMFT/T scores, plaque, and calculus levels. | 24382366 |
| Inflammation, Fibrosis Assessment, Fatty degeneration | Altered Intercellular Communication | The agreement between the donor hospital and study pathologists was substantial regarding evaluation of steatosis (k = 0.623) and fibrosis (k = 0.627) and moderate regarding inflammation (k = 0.495). | 24382833 |
| Inflammation, Anemia, Sickle Cell | Altered Intercellular Communication | Inflammation, leucocyte and red cell adhesion to the endothelium contribute to the pathogenesis of sickle cell anaemia. | 24383847 |
| Inflammation, Coronary Artery Disease, Diabetes Mellitus | Altered Intercellular Communication | The role played by T helper cytokines under chronic, low grade inflammation as seen in type-2 Diabetes Mellitus (T2DM) and Coronary Artery Disease (CAD) co-morbidity is less well studied. | 24383855 |
| Fibrosis Assessment, Tubular atrophy, Interstitial inflammation, MPV17 gene | Altered Intercellular Communication | Category 1: Interstitial fibrosis +- mild interstitial inflammation +- tubular atrophy; no glomerulosclerosis. | 24385054 |
| Fibrosis Assessment, Tubular atrophy, Interstitial inflammation, MPV17 gene | Altered Intercellular Communication | Category 2: Interstitial fibrosis +- mild interstitial inflammation +- tubular atrophy; glomerulosclerosis. | 24385054 |
| Interstitial inflammation, Fibrosis Assessment, Interstitial Fibrosis Assessment, MPV17 gene, Tubular atrophy | Altered Intercellular Communication | Category 3: Moderate or severe interstitial fibrosis, interstitial inflammation and tubular atrophy +- glomerulosclerosis; Category 4: Interstitial inflammation +- tubular atrophy +- glomerulosclerosis; no interstitial fibrosis. | 24385054 |
| Tubulitis Assessment, Interstitial inflammation | Altered Intercellular Communication | Category 5: The prominent change is interstitial inflammation with tubulitis. | 24385054 |
| Inflammation, Interstitial Fibrosis Assessment | Altered Intercellular Communication | Apart from category 0, all had interstitial fibrosis and in category 1, 62 (87.3%) had interstitial fibrosis without inflammation. | 24385054 |
| Interstitial inflammation | Altered Intercellular Communication | Severity of interstitial inflammation increased from category 1 to 3. | 24385054 |
| Fibrosis Assessment, Interstitial inflammation, Glomerulosclerosis (disorder) | Altered Intercellular Communication | The early disease among asymptomatic patients is characterized by interstitial fibrosis without significant interstitial inflammation and glomerular sclerosis with preserved glomerular function. | 24385054 |
| Interstitial inflammation | Altered Intercellular Communication | Although the role of interstitial inflammation in the initiation of the disease is not clear, it appears to have a role in the progression of the disease. | 24385054 |
| Inflammation, Fibrosis Assessment | Altered Intercellular Communication | WNT signaling pathway gene polymorphisms and risk of hepatic fibrosis and inflammation in HCV-infected patients. | 24386373 |
| Inflammation, Fibrosis Assessment, Hepatitis C | Altered Intercellular Communication | This study aimed to determine if genetic variation in Wnt signaling pathway genes are associated with advanced hepatic fibrosis and inflammation risk in a hepatitis C virus (HCV) infected population. | 24386373 |
| Inflammation, Fibrosis Assessment | Altered Intercellular Communication | Among 425 chronically HCV-infected male veterans, 155 (37%) had advanced fibrosis and 180 (42%) had advanced inflammation. | 24386373 |
| Fibrosis, Liver, Inflammation | Altered Intercellular Communication | Polymorphisms in several genes involved in the Wnt signaling pathway were associated with hepatic fibrosis or inflammation risk in HCV-infected males. | 24386373 |
| Infarction, Acute retention of urine, Benign prostatic hypertrophy, prostatitis | Altered Intercellular Communication | To investigate the roles of prostatic infarction, prostatic inflammation and the type of prostatic hyperplasia in acute urinary retention (AUR) in patients with benign prostatic hyperplasia (BPH). | 24386860 |
| Infarction, Benign prostatic hypertrophy, prostatitis | Altered Intercellular Communication | We compared the incidences of prostatic infarction and prostatic inflammation, the types of prostatic hyperplasia, the patients' age, the level of prostate specific antigen (PSA), the prostate volume, and international prostate symptom score (IPSS) between the AUR and non-AUR groups. | 24386860 |
| Infarction, prostatitis | Altered Intercellular Communication | The incidence rate of AUR was 5.620 and 2.326 times higher in the BPH patients with prostatic infarction and prostatic inflammation respectively than in those without (P < 0.05). | 24386860 |
| Infarction, prostatitis | Altered Intercellular Communication | Prostatic infarction and prostatic inflammation are important risk factors of AUR in BPH patients. | 24386860 |
| Inflammation, Helicobacter pylori | Altered Intercellular Communication | Helicobacter pylori colonization of the gastric epithelium induces interleukin-8 (IL-8) production and inflammation leading to host cell damage. | 24387083 |
| Helicobacter pylori, Gastritis | Altered Intercellular Communication | Strain LP-XB7 contributed to a delay in the detection and colonization of H. pylori in rat stomachs, attenuated gastric inflammation, and ameliorated gastric histopathology. | 24387083 |
| Inflammation, Infection caused by Helicobacter pylori | Altered Intercellular Communication | These results suggest that L. plantarum XB7 produces secreted factors capable of modulating inflammation during H. pylori infection, and this probiotic Lactobacillus strain shows promise as an adjunctive therapy for treating H. pylori-associated disease. | 24387083 |
| Heart failure | Altered Intercellular Communication | Short-term changes of neurohormones can give important prognostic information in heart failure (HF) patients. | 24388546 |
| Inflammation, Obesity, Abdominal | Altered Intercellular Communication | Strong associations were found with systemic inflammation, abdominal obesity, and LV mass. | 24388804 |
| Sleep-Disordered Breathing, Inflammation, Metabolic Syndrome X, Obesity | Altered Intercellular Communication | There are a few established risk factors but a number of further risk factors have been suggested including obesity, metabolic syndrome, sleep-disordered breathing, and inflammation. | 24389686 |
| Glucose Metabolism Disorders, Inflammation, Sleep-Disordered Breathing | Altered Intercellular Communication | However, recently suggested potential novel risk factors for AF (inflammation, sleep-disordered breathing, glucose/metabolic disorders) were not confirmed in this study. | 24389686 |
| Inflammation, Atherosclerosis | Altered Intercellular Communication | Inflammation is fundamental to the development of atherosclerosis. | 24390146 |
| Tuberculosis, Pulmonary, Intraocular inflammation, "cytidylyl-(3-5)-cytidine | Altered Intercellular Communication | There was no exacerbation of intraocular inflammation, no postoperative hypotony and no phthisis bulbi in the 16 patients who underwent CPC. | 24390401 |
| Inflammation, Synovitis, Refractory anemias, Edema of bone marrow, Enthesitis | Altered Intercellular Communication | The aim of this study was to investigate the ability of whole-body MRI (WBMRI) to visualize inflammation [synovitis, bone marrow oedema (BME) and enthesitis] and structural damage in patients with RA. | 24390938 |
| Inflammation, Superficial ulcer, Peripheral, Synovitis, Enthesitis | Altered Intercellular Communication | Short Tau Inversion Recovery and pre- and post-contrast T1-weighted images were evaluated for readability and the presence/absence of inflammation (synovitis, BME and enthesitis) and structural damage (erosions and fat infiltrations) in 76 peripheral joints, 30 entheseal sites and in the spine. | 24390938 |
| Inflammation | Altered Intercellular Communication | Peripheral and axial inflammation and structural damage at joints and entheses was frequently identified by WBMRI, and more frequently than by clinical examination. | 24390938 |
| Refractory anemias, Inflammation | Altered Intercellular Communication | WBMRI is a promising tool for evaluation of the total inflammatory load of inflammation (an MRI joint count) and structural damage in RA patients. | 24390938 |
| Gastrointestinal inflammation | Altered Intercellular Communication | Macrophages regulate innate immunity to maintain intestinal homeostasis and play pathological roles in intestinal inflammation. | 24391216 |
| Gastrointestinal inflammation | Altered Intercellular Communication | This study was to investigate whether EGFR activation in macrophages regulates cytokine production and intestinal inflammation. | 24391216 |
| Gastrointestinal inflammation | Altered Intercellular Communication | Thus, although selective deletion of EGFR in macrophages leads to increases in both pro- and anti-inflammatory cytokines in response to inflammatory stimuli, the increase in the IL-10 level plays a role in suppressing proinflammatory cytokine production, resulting in protection of mice from intestinal inflammation. | 24391216 |
| Inflammation, Cardiomyopathies, Myocarditis, CTCAE 5.0, Influenza-like symptoms, Juvenile rheumatoid arthritis | Altered Intercellular Communication | A 20-year-old pregnant woman with a history of juvenile idiopathic arthritis presented with flu-like symptoms, systemic inflammation with myocarditis, and severe cardiomyopathy. | 24391342 |
| Malignant neoplasm of urinary bladder, Inflammation, Primary malignant neoplasm, Neoplasms | Altered Intercellular Communication | The relationship between inflammation and cancer is well established in several tumor types, including bladder cancer. | 24391818 |
| Alzheimers Disease", Data types - Address | Altered Intercellular Communication | CHRNA7 encodes the a7 nicotinic acetylcholine receptor subunit, which is important to Alzheimer's disease (AD) pathogenesis and cholinergic neurotransmission. | 24391883 |
| Inflammation | Altered Intercellular Communication | Additionally, vascular function was associated with inflammatory markers, suggesting that the favourable influence of physical activity may be mediated by its effect on inflammation. | 24392783 |
| Inflammation, Epithelial | Altered Intercellular Communication | Salmeterol reduced some biomarkers of alveolar inflammation and epithelial injury. | 24392848 |
| Intraocular inflammation | Altered Intercellular Communication | Relationship between suspected reasons of intraocular inflammation and the results of diagnostic vitrectomy: an observational study. | 24392961 |
| Communicable Diseases, Inflammation, Inflammatory disorder | Altered Intercellular Communication | Intraocular inflammation of the posterior segment may be associated with neoplastic, infectious, and inflammatory diseases. | 24392961 |
| Intraocular inflammation | Altered Intercellular Communication | We therefore aimed to investigate the safety and usefulness of diagnostic vitrectomy in intraocular inflammation. | 24392961 |
| Inflammation | Altered Intercellular Communication | We hypothesized a strong association between HR at rest and subclinical inflammation, given their common interrelation with the autonomic nervous system. | 24393259 |
| Inflammation, Cardiovascular Diseases | Altered Intercellular Communication | In conclusion, an increased HR at rest was associated with a higher level of inflammation among an ethnically diverse group of subjects without known cardiovascular disease. | 24393259 |
| Inflammation | Altered Intercellular Communication | Mucosa-associated lymphoid tissue (MALT) lymphoma usually arises from chronic inflammation. | 24395281 |
| Inflammation, Blind Loop Syndrome | Altered Intercellular Communication | Gastrointestinal reconstruction may be responsible for underlying chronic inflammation via small intestinal bacterial overgrowth. | 24395281 |
| Slovenia, glycation, Inflammation, Diabetic Neuropathies | Altered Intercellular Communication | We asked whether the receptor of advanced glycation end products (RAGE) is related to dermal inflammation in nonsystemic vasculitic neuropathy (NSVN) and diabetic neuropathy (DN) and whether its presence in skin is comparable to that in sural nerve biopsies. | 24395344 |
| Inflammation | Altered Intercellular Communication | Dermal RAGE is increased in NSVN and DN, supporting the concept of a role of the RAGE pathway in the pathophysiology of dermal inflammation and skin denervation in NSVN and DN. | 24395344 |
| Inflammation, Atrophy of mucosa of stomach, Autoimmune Atrophic Chronic Gastritis | Altered Intercellular Communication | Atrophic autoimmune gastritis (AAG) is a condition of chronic inflammation and atrophy of stomach mucosa, for which development can be partially triggered by the bacterial pathogen Helicobacter pylori (HP). | 24395566 |
| Inflammation, Sensorineural Hearing Loss (disorder), Cholangitis, Facial paralysis | Altered Intercellular Communication | The conclusion is that sensorineural hearing loss and facial palsy in patients with MPO-ANCA related angitis occurred due to strong inflammation in the cochlea or facial nerve. | 24397116 |
| Rupture, Athletic Injuries, Inflammation, Hyaline degeneration, Necrosis, Giant Cell Tumors, Structure of achilles tendon | Altered Intercellular Communication | Of 9 cases, 6 were male and 3 were female with an average age of 43 years (range, 21-65 years), including 5 cases of chronic Achilles tendon ruptures caused by sport injury and 4 cases of Achilles tendon defects caused by resection of tendon lesion (2 cases of hyaline degeneration with necrosis, 1 case of giant cell tumor, and 1 case of chronic inflammation with hyaline degeneration). | 24397131 |
| Inflammation, Asthma | Altered Intercellular Communication | Aeroallergen and food IgE sensitization and local and systemic inflammation in asthma. | 24397423 |
| Airway structure, Sensitization (observable entity) | Altered Intercellular Communication | We recently reported an independent association between IgE sensitization to food allergens and increased airway inflammation, assessed by fraction of exhaled nitric oxide (FeNO), in a population-based study (J Allergy Clin Immunol, 130, 2012, 397). | 24397423 |
| Inflammation, Asthma, Sensitization (observable entity) | Altered Intercellular Communication | Independent effects of IgE sensitization to aeroallergens (furry animals and mould) and food allergens were found on both local and systemic markers of inflammation in asthma. | 24397423 |
| Inflammation, Asthma | Altered Intercellular Communication | The finding regarding food IgE sensitization is novel, and a clinical implication might be that even food sensitization must be assessed to fully understand inflammation patterns in asthma. | 24397423 |
| Inflammation, Atherosclerosis | Altered Intercellular Communication | Using MAP, several low abundance proteins implicated in atherosclerosis and inflammation were found on HDL. | 24397693 |
| Inflammation, Thrombosis, Angiogenic Process | Altered Intercellular Communication | Ramipril is associated with an increase in the biomarkers of angiogenesis/arteriogenesis and reduction in the markers of thrombosis, inflammation, and leukocyte adhesion. | 24397981 |
| Inflammatory abnormality of the eye | Altered Intercellular Communication | Ultrasound biomicroscopy in chronic pseudophakic ocular inflammation associated with misplaced intraocular lens haptics. | 24398393 |
| Inflammation, Damage, Chemical injury | Altered Intercellular Communication | Results of all the nerve biopsies were abnormal, showing axonal damage (7 patients), inflammation (7 patients), signs of ischemic injury (7 patients), and nerve microvasculitis (6 patients). | 24398433 |
| Inflammation, Atherosclerosis | Altered Intercellular Communication | Liver X receptors (LXRs) are nuclear receptors whose activation protects against atherosclerosis by transcriptional regulation of genes important in promoting cholesterol efflux and inhibiting inflammation. | 24398515 |
| Inflammation | Altered Intercellular Communication | These needle-like crystals induce not only acute episodes of inflammatory process into the surrounding area, but also, in the long-term history of the disease, chronic inflammation that is associated with changes in articular and periarticular structures. | 24399012 |
| Inflammation, Neoplasms, Autoimmune Diseases, Unknown (origin) (qualifier value), Pachymeningitis | Altered Intercellular Communication | Pachymeningitis is a progressive disease resulting in a diffuse thickening of dura mater due to inflammation, tumor or autoimmune diseases, but most cases are idiopathic. | 24399188 |
| Inflammation, Chronic Kidney Diseases | Altered Intercellular Communication | Serum irisin levels were quantified by ELISA and correlated with anthropometric and biochemical parameters of renal function, glucose and lipid metabolism, as well as inflammation, in 532 patients with stages 1-5 of chronic kidney disease (CKD). | 24399249 |
| Inflammation, One Vessel Coronary Disease | Altered Intercellular Communication | Inflammation is a prominent pathological feature of small vessel disease. | 24399375 |
| PVR wt Allele, Inflammation | Altered Intercellular Communication | We examined the association between inflammation, PVS, and WMH in the Lothian Birth Cohort 1936 (N=634). | 24399375 |
| Inflammation, Cerebrovascular accident | Altered Intercellular Communication | After accounting for age, sex, stroke, and vascular risk factors, PVS were significantly associated with WMH (b=0.47; P<0.0001); Inflammation was weakly but significantly associated with PVS (b=0.12; P=0.048), but not with WMH (b=0.02; P=NS). | 24399375 |
| Inflammation, One Vessel Coronary Disease | Altered Intercellular Communication | Longitudinal studies should examine whether visible PVS predate WMH progression and whether inflammation modulators can prevent small vessel disease. | 24399375 |
| Inflammation, Abdominal Pain, Hyponatremia | Altered Intercellular Communication | A 41-year-old woman, suffering from continuous abdominal pain, only presented a non-specific inflammation of the whole colon and an unclaryfied hyponatriaemia; in spite of the only doubtful explanation by an enormous elongation of the colon, it was partially resected. | 24399476 |
| Inflammation | Altered Intercellular Communication | Human butyrylcholinesterase (BuChE) and paraoxonase-1 (PON1) are two major bioscavenger enzymes that are associated with inflammation, oxidative stress and lipid metabolism. | 24399815 |
| Neurogenic Inflammation, Trigeminal nerve structure | Altered Intercellular Communication | It represents a unique proof of principle in that not only trigeminal nerve pain but also presumed neurogenic inflammation can be relieved by blockade of cervical nociceptive inputs. | 24401103 |
| Autoimmune Diseases, Inflammation, Dermatomyositis, Childhood Type | Altered Intercellular Communication | Juvenile dermatomyositis is a rare autoimmune disease that causes inflammation of the skin and muscles. | 24401174 |
| Inflammation, HIV Infections, Cardiovascular Diseases | Altered Intercellular Communication | HIV infection causes systemic immune inflammation, and increases the risk for cardiovascular (CVD) disease even among those on virologically suppressive anti-retroviral treatment (ART). | 24401216 |
| Intestinal metaplasia of gastric mucosa, Inflammation, Gastritis, Gastritis, Atrophic, Chronic gastritis | Altered Intercellular Communication | Among H pylori-positive participants, prevalence was 94% for acute gastritis, 100% for chronic gastritis, 21% for gastric atrophy and 11% for intestinal metaplasia of the gastric mucosa, while chronic inflammation severity was mild in 9%, moderate in 47% and severe in 43%. | 24401722 |
| Airway structure, Asthma, IL13 gene, Cerebrovascular accident | Altered Intercellular Communication | Perennial allergic rhinitis may be relevant for CVA patients as well as classic asthma patients by consistently augmenting eosinophilic lower airway inflammation. | 24401902 |
| Inflammation, Primary malignant neoplasm, Cachexia | Altered Intercellular Communication | Systemic inflammation contributes to both the development of cancer and of cachexia. | 24402361 |
| Inflammation, Low muscle mass, Endothelial dysfunction | Altered Intercellular Communication | Increasing physical activity, consuming a diet with a high proportion of energy from carbohydrates, and taking steps to prevent insulin resistance and reduce inflammation and endothelial dysfunction may help to reduce the risk of low muscle mass in older men. | 24402385 |
| Sleep Apnea, Obstructive | Altered Intercellular Communication | Abstract Inflammation plays a critical role in the pathogenesis of obstructive sleep apnea syndrome (OSAS). | 24405178 |
| Juvenile arthritis, Inflammation, Uveitis | Altered Intercellular Communication | Children with JIA are at risk of inflammation of the uvea in the eye (uveitis). | 24405833 |
| Inflammation, Uveitis | Altered Intercellular Communication | In the initial stages of mild to moderate inflammation the uveitis is asymptomatic. | 24405833 |
| HD Term Type, Inflammation | Altered Intercellular Communication | Inflammation and glycemic control are important prognosis-related factors for hemodialysis (HD) patients; moreover, inflammation affects insulin secretion. | 24405885 |
| Inflammation, Endothelium | Altered Intercellular Communication | Glomerular inflammation correlates with endothelial injury, monocyte influx, and IL-6 and IL-b secretion by circulating immune cells. | 24406453 |
| Inflammation, Comorbidity | Altered Intercellular Communication | Analyses were adjusted for demographics measures, disease severity indicators, inflammation, comorbidity and medication. | 24407045 |
| Cessation of life, Sepsis, Multiple Organ Failure, Inflammation | Altered Intercellular Communication | Death from sepsis in the intensive care unit (ITU) is frequently preceded by the development of multiple organ failure as a result of uncontrolled inflammation. | 24408035 |
| Coronary artery ectasia, Inflammation, CDE protocol-cyclophosphamide/doxorubicin/etoposide | Altered Intercellular Communication | Previous studies have demonstrated that inflammation, neurohormonal process and cardiovascular risk factors are associated with the development of coronary artery ectasia (CAE). | 24408063 |
| Inflammation, Cardiovascular Diseases | Altered Intercellular Communication | The neutrophil to lymphocyte (N/L) ratio has recently emerged as a new inflammation marker for cardiovascular disease. | 24408063 |
| Inflammation, Coronary Artery Disease | Altered Intercellular Communication | In this study, we hypothesised that CAE could be associated with more severe inflammation compared to obstructive coronary artery disease (O-CAD) with regard to N/L ratio values. | 24408063 |
| Inflammation, Subarachnoid Hemorrhage | Altered Intercellular Communication | ADMA levels and arginine/ADMA ratios reflect severity of disease and extent of inflammation after subarachnoid hemorrhage. | 24408146 |
| Inflammation, Endothelial dysfunction | Altered Intercellular Communication | This might indicate that endothelial dysfunction, with ADMA as a marker, is induced by a systemic inflammation. | 24408146 |
| Cessation of life, Coronary Aneurysm, Inflammation, Myocardial Ischemia | Altered Intercellular Communication | We report an autopsy case of a coronary aneurysm with massive adventitial inflammation post-percutaneous coronary intervention with sirolimus-eluting stent (SES) insertion in the left circumflex (LCX) coronary artery for ischemic heart disease 3 years prior to death. | 24408671 |
| Coronary Aneurysm, Inflammation | Altered Intercellular Communication | Chronic inflammation can lead to the development of coronary artery aneurysms. | 24408671 |
| Inflammation | Altered Intercellular Communication | Furthermore, significantly high-grade inflammation and evidence of active H. pylori-induced gastritis was observed in the "DWP" type (P < 0.001). | 24409067 |
| Inflammation, Gastritis | Altered Intercellular Communication | CO whiteness detected via ME was associated with histological evidence of gastritis and helps to predict the severity of inflammation and H. pylori-induced activity. | 24409067 |
| Inflammation, Primary malignant neoplasm | Altered Intercellular Communication | An inflammation based score can optimize the selection of patients with advanced cancer considered for early phase clinical trials. | 24409281 |
| Inflammation, Primary malignant neoplasm | Altered Intercellular Communication | As inflammation is pathogenic and prognostic in cancer we investigated the prognostic performance of inflammation-based indices including the neutrophil (NLR) and platelet to lymphocyte ratio (PLR). | 24409281 |
| Inflammation | Altered Intercellular Communication | UVA rays present in sunlight are able to reach the dermal skin layer generating reactive oxygen species (ROS) responsible for oxidative damage, alterations in gene expression, DNA damage, leading to cell inflammation, photo-ageing/-carcinogenesis. | 24409282 |
| Communicable Diseases, Inflammation | Altered Intercellular Communication | Calcium binding-mediated sustained release of minocycline from hydrophilic multilayer coatings targeting infection and inflammation. | 24409292 |
| Communicable Diseases, Inflammation | Altered Intercellular Communication | Infection and inflammation are common complications that seriously affect the functionality and longevity of implanted medical implants. | 24409292 |
| Communicable Diseases, Acidosis | Altered Intercellular Communication | pH-responsive minocycline release was observed as the chelation between minocycline and Ca(2+) is less stable at acidic pH, enabling 'smart' drug delivery in response to infection and/or inflammation-induced tissue acidosis. | 24409292 |
| Inflammation, Psoriasis, Dyslipidemias, Coronary heart disease, Diabetes Mellitus, Psoriatic Juvenile Idiopathic Arthritis, Hypertension, CTCAE | Altered Intercellular Communication | Psoriatic patients have significantly greater risks of developing coronary heart disease than controls in relationship with psoriasis comorbidities such as hypertension, diabetes, dyslipidemia, inflammation and probably with psoriasis itself. | 24409658 |
| Inflammation, Periodontitis, Diabetes Mellitus, Non-Insulin-Dependent | Altered Intercellular Communication | Serum C-reactive protein (CRP) is elevated in both periodontitis and type 2 diabetes mellitus through inflammation. | 24410292 |
| palladium, Inflammation, Periodontitis, Hyperglycemia | Altered Intercellular Communication | Logistic regression models with survey procedures were used to explore the roles of inflammation levels from serum CRP and periodontal pathogens on the relations with periodontitis, including PD, CAL, and hyperglycemia, and their joint associations with interaction terms. | 24410292 |
| Periodontitis | Altered Intercellular Communication | This may suggest that chronic inflammatory conditions could increase the impact of periodontitis on hyperglycemic status. | 24410292 |
| Inflammation, Gangrene, Perforation (observation), Specimen Source Codes - Abscess | Altered Intercellular Communication | The degree of inflammation of the resected specimens was grossly assessed and graded into acute inflammation, acute inflammation with complications (such as gangrene, perforation, abscess) and un-inflamed appendix. | 24411549 |
| Inflammation, Retinitis Pigmentosa, Non-Small Cell Lung Carcinoma | Altered Intercellular Communication | We assessed the association between RP and white blood cell (WBC) count, an established metric of systemic inflammation, after RT for non-small cell lung cancer. | 24411603 |
| Inflammation, Superficial ulcer | Altered Intercellular Communication | At diagnosis, colonoscopy showed modest inflammation and few superficial ulcerations and erosions in the ileo-cecal valve and the terminal ileum. | 24411923 |
| Inflammation, Dental Plaque, Atherosclerotic lesion | Altered Intercellular Communication | The integrin avb3 is expressed by macrophages and angiogenic endothelial cells in atherosclerotic lesions and thus is a marker of plaque inflammation and, potentially, of plaque vulnerability. | 24412187 |
| Inflammation | Altered Intercellular Communication | Based on these initial data, larger prospective studies are now warranted to evaluate the potential of molecular imaging of avb3 expression for assessment of plaque inflammation in patients. | 24412187 |
| Traumatic injury | Altered Intercellular Communication | Laboratory of Inflammation Biology and Surgical Science and multi-institution level 1 trauma centers. | 24413577 |
| Single organ dysfunction, Inflammation, Bacterial Infections | Altered Intercellular Communication | Correlation analyses revealed significant correlations of miR-133a with disease severity, classical markers of inflammation and bacterial infection, and organ failure. | 24413579 |
| Intraocular inflammation, Uveitis | Altered Intercellular Communication | Examination revealed an anterior uveitis and despite an initial response to topical steroids, the intraocular inflammation worsened with anterior and posterior uveitis development. | 24413827 |
| Intraocular inflammation | Altered Intercellular Communication | After improvement and tapering of this treatment, the intraocular inflammation reoccurred. | 24413827 |
| Fibrosis Assessment, Mucocele of appendix | Altered Intercellular Communication | In asymptomatic patients without appendiceal inflammation, the appendix can be dilated by intraluminal material such as inspissated succus in cystic fibrosis or mucus from benign appendiceal mucocele. | 24414145 |
| Appendicitis, CTCAE, Pathology | Altered Intercellular Communication | Attention to mural features, cecal configuration, and periappendiceal inflammation is essential to the correct prospective diagnosis of complicated appendicitis and less common appendiceal pathologies. | 24414145 |
| Inflammation, Cerebral Ischemia | Altered Intercellular Communication | Cerebral ischemia triggers a cascade of cellular processes, which induce neuroprotection, inflammation, apoptosis and regeneration. | 24415059 |
| Inflammation, Chronic Kidney Insufficiency, Chronic Kidney Diseases | Altered Intercellular Communication | Race modifies the association between adiposity and inflammation in patients with chronic kidney disease: findings from the chronic renal insufficiency cohort study. | 24415732 |
| Inflammation, Chronic Kidney Diseases | Altered Intercellular Communication | The race-specific association of inflammation with adiposity and muscle mass in subjects with chronic kidney disease (CKD) was examined. | 24415732 |
| Inflammation, ABCA4 gene | Altered Intercellular Communication | Race stratified analysis showed that the association between biomarkers and BFM and FFM differed by race, with Caucasians, demonstrating a stronger association with markers of inflammation than African Americans. | 24415732 |
| Inflammation, ABCA4 gene, Chronic Kidney Diseases | Altered Intercellular Communication | BFA and FFM are positively associated with markers of inflammation in patients with CKD. | 24415732 |
| Inflammation | Altered Intercellular Communication | Race stratified analysis showed that Caucasians have a stronger association with markers of inflammation compared to African Americans. | 24415732 |
| Inflammation | Altered Intercellular Communication | The reciprocal regulation between Del-1 and inflammation may contribute to optimally balance the protective and the potentially harmful effects of inflammatory cell recruitment. | 24416060 |
| Inflammation, Merkel cell carcinoma, Merkel cell polyomavirus | Altered Intercellular Communication | PD-L1 expression in the Merkel cell carcinoma microenvironment: association with inflammation, Merkel cell polyomavirus and overall survival. | 24416729 |
| Inflammation, Progranulins, Obesity | Altered Intercellular Communication | C1q/TNF-related protein-3 (CTRP-3), an adiponectin paralog, and progranulin were recently identified as novel adipokines which may link obesity with glucose dysregulation and subclinical inflammation. | 24417980 |
| Inflammation, Idiopathic Pulmonary Fibrosis | Altered Intercellular Communication | The immune response plays an unsettled role in the pathogenesis of idiopathic pulmonary fibrosis (IPF), the contribution of inflammation being controversial as well. | 24418172 |
| Communicable Diseases, Inflammation | Altered Intercellular Communication | At an age when infection, inflammation and airway wall remodeling are minimal, neonates with CF had an acidic nasal ASL compared to babies without CF. | 24418186 |
| Inflammation, Duodenal villous atrophy, Crypt | Altered Intercellular Communication | In the duodenal mucosa, total or subtotal duodenal villous atrophy, inflammation, crypt distortion, and increased apoptotic bodies were the most common features. | 24418855 |
| methyldopa, Inflammation, Visual Impairment, Blindness | Altered Intercellular Communication | Age-related macular degeneration (AMD) is the leading cause of irreversible visual impairment and blindness among persons aged 60 years and older and many theories exist and feature mechanisms of oxidative stress, atherosclerotic-like changes, genetic predisposition, and inflammation in development of AMD. | 24418867 |
| methyldopa, Inflammation, Atherosclerosis | Altered Intercellular Communication | Our data support the role of chronic inflammation in the development of AMD, however, further studies are needed to determine which common disease mechanisms of chronic inflammation and atherosclerosis contribute to the pathogenesis of AMD. | 24418867 |
| Inflammation, Malignant Neoplasms | Altered Intercellular Communication | Pleural biopsies were obtained through medical pleuroscopy that revealed mild chronic inflammation with prominent eosinophils and no evidence for malignancy. | 24419196 |
| Inflammation | Altered Intercellular Communication | The elevation of serum CEA might be attributed to the presence of local inflammation in the lung. | 24419710 |
| Inflammation, Fibrosis Assessment, FBN2 wt Allele, Infestation | Altered Intercellular Communication | Ov infestation caused chronic inflammation of the biliary tree by periductal fibrosis (PDF), which may subsequently lead to CCA development. | 24420706 |
| Injury of kidney | Altered Intercellular Communication | Transcriptional repressor activating transcription factor 3 (ATF3) is induced by various stress stimuli, including inflammation-induced renal injury. | 24420912 |
| Inflammation, Fibrosis Assessment | Altered Intercellular Communication | Liver and white adipose tissue (WAT) develop inflammation and fibrosis. | 24423338 |
| Inflammation | Altered Intercellular Communication | Knowledge about the interrelationship between adiposity and systemic low-grade inflammation during pubertal growth is important in detecting early signs of obesity-related metabolic disorders. | 24423339 |
| Inflammation | Altered Intercellular Communication | FM explained the variance of hsCRP during pubertal growth, but the reverse was not true, which suggests that FM contributes to low-grade inflammation and not vice versa. | 24423339 |
| ARCN1 gene, Colonization, Airway structure | Altered Intercellular Communication | Even in the absence of clinical exacerbation, colonization by bacterial pathogens in COPD was associated with a clinically significant moderate increase in daily symptoms, likely mediated by increased airway inflammation. | 24423399 |
| Inflammation, Atherosclerosis | Altered Intercellular Communication | Physical activity can prevent and/or attenuate atherosclerosis, a disease clearly linked to inflammation. | 24423463 |
| Inflammation | Altered Intercellular Communication | Discovery of molecular pathways mediating 1,25-dihydroxyvitamin D3 protection against cytokine-induced inflammation and damage of human and male mouse islets of Langerhans. | 24424042 |
| therapeutic hemodilution | Altered Intercellular Communication | CEA may be affected in obese individuals by several factors, including but not limiting to hemodilution, inflammatory conditions, and insulin resistance. | 24425143 |
| methyldopa, Age related macular degeneration | Altered Intercellular Communication | Oxidant- and inflammation-induced damage to retinal pigment epithelial (RPE) cells is central to the pathogenesis of age-related macular degeneration (AMD). | 24426777 |
| methyldopa, Inflammation | Altered Intercellular Communication | Given the crucial causative roles of oxidative stress and inflammation in AMD pathogenesis, knowing whether OTC might exhibit a similar benefit in this cell and tissue type has high clinical relevance; thus, we evaluated OTC in the present study. | 24426777 |
| Inflammation, Xanthomatosis | Altered Intercellular Communication | To provide further insights into the pathophysiology of NXG, we evaluated the plasma lipid phenotype, mechanisms involved in cellular cholesterol accumulation and role of MIg in an analysis of blood and plasma markers of inflammation in 16 patients with xanthomatosis [NXG (n = 8) and NX (n = 8)] associated with monoclonal IgG relative to the relevant controls. | 24428816 |
| Inflammation, Glomerulonephritis | Altered Intercellular Communication | Patients with ANCA-associated glomerulonephritis had significantly higher levels of suPAR compared with the other disease groups, which may be owing to their lower renal function and systemic inflammation. | 24429394 |
| Inflammation, Dysbiosis | Altered Intercellular Communication | It is unlikely that a single bacterium perpetuates inflammation in late stage CD; dysbiosis was common and we found no evidence of increased bacterial translocation. | 24429583 |
| Aphthous Stomatitis, Inflammation, Granuloma | Altered Intercellular Communication | We believe that future studies should focus on early disease and viable bacteria in nodes, aphthous ulcers and granulomas, as they may be more relevant in the initiation of inflammation in CD. | 24429583 |
| Inflammation, Microbleeds | Altered Intercellular Communication | T2-based imaging showed microbleeds and analysis of the apolipoprotein E (ApoE) genotype showed e4/e4; therefore, cerebral amyloid angiopathy-related inflammation was diagnosed. | 24429648 |
| ARCN1 gene, Inflammation | Altered Intercellular Communication | In models of COPD, environmental stressors induce innate immune responses, inflammasome activation and inflammation. | 24430176 |
| ARCN1 gene, Pneumonitis | Altered Intercellular Communication | However, the interaction between these responses and their role in driving pulmonary inflammation in stable COPD is unknown. | 24430176 |
| Inflammation | Altered Intercellular Communication | Data on MRI inflammation were compared with clinical inflammation and baseline radiological erosions. | 24431393 |
| Superficial ulcer, Inflammation, Anti-Citrullinated Protein Antibodies, Trauma, Nervous System, Rheumatoid Factor | Altered Intercellular Communication | Baseline erosions were an independent predictor and not a mediator between symptom duration, systemic or local clinical inflammation (erythrocyte sedimentation rate (ESR), swollen joint count (SJC)) or autoantibodies (anti-citrullinated-peptide antibodies, rheumatoid factor) and radiological damage. | 24431393 |
| Inflammation, Superficial ulcer | Altered Intercellular Communication | Subclinical MRI inflammation was studied in relation to erosions, revealing that 83% of the non-swollen joints with baseline erosions had subclinical MRI inflammation compared with 25% of the non-swollen joints without baseline erosions (OR 15.2 95% CI 3.1 to 102.1). | 24431393 |
| Inflammation, Superficial ulcer | Altered Intercellular Communication | The association between MRI inflammation and baseline erosions was independent of symptom duration, ESR, SJC and autoantibodies. | 24431393 |
| Superficial ulcer, Damage, Inflammation | Altered Intercellular Communication | Baseline erosions are a predictor for future joint damage, independent of known predictors as time, autoantibodies or clinical measurable inflammation. | 24431393 |
| Inflammation | Altered Intercellular Communication | Subclinical inflammation is suggested as an underlying mechanism. | 24431393 |
| Communicable Diseases, Inflammation | Altered Intercellular Communication | Interleukin-1 (IL-1) is a cytokine critical to inflammation, immunological activation, response to infection, and bone marrow hematopoiesis. | 24433038 |
| Inflammation, Sleep Apnea, Obstructive | Altered Intercellular Communication | The additive impact of periodic limb movements during sleep on inflammation in patients with obstructive sleep apnea. | 24433139 |
| Inflammation, Sleep Apnea, Obstructive, Sleep Disorders, Osage language | Altered Intercellular Communication | Both periodic limb movements during sleep (PLMS) and obstructive sleep apnea (OSA) are major causes of sleep disorders and have been associated with systemic inflammation and cardiovascular events. | 24433139 |
| Inflammation, Osage language | Altered Intercellular Communication | To investigate whether the presence of PLMS is associated with increased inflammation in patients suspected of having OSA. | 24433139 |
| Kidney Failure, Chronic, Inflammation, Cardiovascular Diseases | Altered Intercellular Communication | Patients with end-stage renal disease (ESRD) are at an increased risk of cardiovascular disease due to many factors including inflammation and oxidative stress. | 24434384 |
| ARCN1 gene, Inflammation, Chronic Obstructive Airway Disease | Altered Intercellular Communication | Chronic obstructive pulmonary disease (COPD), low lung function independent of diagnosis and markers of inflammation are all associated with increased morbidity and mortality. | 24435009 |
| ETV3 wt Allele, Large prostate, Benign prostatic hypertrophy, prostatitis | Altered Intercellular Communication | In conclusion, in males of infertile couples, MetS is positively associated with prostate enlargement, biochemical (sIL8) and ultrasound-derived signs of prostate inflammation but not with prostate-related symptoms, which suggests that MetS is a trigger for a subclinical, early-onset form of benign prostatic hyperplasia. | 24435050 |
| Inflammation, Community acquired pneumonia | Altered Intercellular Communication | Bedside monitoring of ventilation distribution and alveolar inflammation in community-acquired pneumonia. | 24435618 |
| Pneumonitis | Altered Intercellular Communication | FENO could be a prospective supplementary tool to describe local lung inflammation as individual trend parameter. | 24435618 |
| Inflammation, Primary malignant neoplasm | Altered Intercellular Communication | Serum prostate specific antigen (PSA) may be elevated in otherwise healthy men; systemic inflammation has been associated with cancer. | 24435840 |
| Inflammation, Prostatic Diseases | Altered Intercellular Communication | Markers of systemic inflammation were associated with elevated PSA in men without known prostatic disease. | 24435840 |
| Malnutrition | Altered Intercellular Communication | Malnutrition inflammation score at 6 months (P = .006) and erythropoietin (EPO) dose requirements were higher in the CON group (P = .012). | 24436491 |
| ARCN1 gene, Inflammation, physiopathological | Altered Intercellular Communication | Inactivity and systemic inflammation could play a role in the development of limb muscle dysfunction in COPD. | 24438094 |
| ARCN1 gene, Inflammation, physiopathological | Altered Intercellular Communication | The reduced level of daily activities and evidence of systemic inflammation in these individuals suggest that these factors precede the development of overt limb muscle dysfunction in COPD. | 24438094 |
| Crohn Disease, Inflammation | Altered Intercellular Communication | We examined the outcomes of consecutively performed laparoscopic-assisted ileocecectomy for Crohn's disease (CD), with particular focus on FT's effects in patients with underlying bowel inflammation. | 24439590 |
| Choroiditis | Altered Intercellular Communication | All 7 specimens displayed persistent choroidal inflammation, in 1 case 208 days after injection. | 24439760 |
| Retinal Detachment, Inflammation, Fibrous | Altered Intercellular Communication | Although no organisms were identified in the examined tissues, persistent inflammation was present in all cases, and fibrous proliferation resulted in cyclitic membrane formation and retinal detachment in all enucleated globes. | 24439760 |
| Inflammation | Altered Intercellular Communication | These findings suggest that potential globe-salvaging interventions must address a pattern of changes involving persistent, chronic inflammation and fibrovascular proliferation as key components. | 24439760 |
| Inflammation, Diabetes Mellitus, Chronic Kidney Diseases, Cardiovascular Diseases | Altered Intercellular Communication | Kidney donors comprise a highly screened population without risk factors such as diabetes and inflammation, which invariably confound the association between CKD and cardiovascular disease. | 24439974 |
| Airway structure, Cystic Fibrosis, Destruction (action) | Altered Intercellular Communication | Airway inflammation, mediated in part by LTB4, contributes to lung destruction in patients with cystic fibrosis (CF). | 24440167 |
| Airway structure | Altered Intercellular Communication | LTB(4)-receptor inhibition may reduce airway inflammation. | 24440167 |
| Peripheral Vascular Diseases, Inflammation | Altered Intercellular Communication | Studies about inflammation on percutaneous transluminal angioplasty with stent (PTA/stent) to treat peripheral arterial disease (PAD) in humans are scarce. | 24440188 |
| Communicable Diseases, Inflammation | Altered Intercellular Communication | Chronic cytomegalovirus (CMV) infection may contribute significantly to T-cell immunosenescence, chronic inflammation, and adverse health outcomes in older adults. | 24440388 |
| Inflammation, Defense, Certified Midwife | Altered Intercellular Communication | Host defense defects in the HBV-infected group may lead to a lower intensity of inflammation in the pathogenesis of CM compared with the HBV-uninfected patients and may account for these divergences between the two groups. | 24440644 |
| Inflammation, Fibrosis Assessment, Biliary cirrhosis, Liver Failure | Altered Intercellular Communication | It is characterized by progressive inflammation and fibrosis of the bile ducts leading to biliary cirrhosis and eventually liver failure. | 24440929 |
| Inflammatory Bowel Diseases, Inflammation | Altered Intercellular Communication | Subunits of calprotectin, a fecal marker of inflammation in inflammatory bowel disease, have been recently identified in bile. | 24440929 |
| Pharyngitis | Altered Intercellular Communication | Moreover, the expression rates of integrin av protein in NPC tissues was 76.92%, significantly higher than that of nasopharyngeal inflammation tissues (6.25%, P< 0.05). | 24440971 |
| Sprue, Inflammation | Altered Intercellular Communication | Histologic findings suggesting tropical sprue in the appropriate clinical context include incomplete duodenal villous blunting without development of flat mucosa, frequent involvement of the terminal ileum with more marked inflammation and villous blunting than in the duodenum, and a conspicuous eosinophil infiltrate in the lamina propria. | 24441659 |
| Inflammation, Carcinoma, Ulcerative Colitis, Granulomatous inflammation, Neoplastic Polyp, Non-Neoplastic Disorder | Altered Intercellular Communication | Out of 126 colonoscopic biopsies 34(27%) showed chronic nonspecific inflammation, followed by carcinoma 25(19.8%), non-neoplastic polyps 21(16.7%), granulomatous inflammation 14(11.1%), neoplastic polyps 8(6.3%), ulcerative colitis 4(3.2%). | 24442164 |
| Inflammation, Aggressive behavior, Hyperplasia | Altered Intercellular Communication | There were no features to suggest a reactive hyperplasia in response to inflammation or of aggressive behaviour. | 24442176 |
| Inflammation, Obesity, Cardiovascular Diseases | Altered Intercellular Communication | There is evidence that the link between obesity and cardiovascular disease might relate to inflammation in both fat tissue and the arterial wall. | 24442596 |
| Vasculitis | Altered Intercellular Communication | (18)F-FDG uptake on PET is a surrogate marker of vessel wall inflammation. | 24442596 |
| Steatitis | Altered Intercellular Communication | Increasing body weight significantly predicted the level of fatty inflammation. | 24442596 |
| Increased insulin level, Inflammation, Malignant neoplasm of liver, Obesity, FAM126A gene | Altered Intercellular Communication | Elevated levels of biomarkers of inflammation and hyperinsulinemia are associated with a higher risk of HCC, independent of obesity and established liver cancer risk factors. | 24443059 |
| Inflammation, Adenoma of large intestine | Altered Intercellular Communication | Oxidative balance score, colorectal adenoma, and markers of oxidative stress and inflammation. | 24443405 |
| Sepsis, Inflammation, Observation Method - Coagulation | Altered Intercellular Communication | Inflammation and coagulation are closely interrelated pathophysiologic processes in the pathogenesis of sepsis. | 24443891 |
| Malignant Lesion, Nodular fasciitis | Altered Intercellular Communication | Nodular fasciitis is a rare and benign inflammatory condition; however, it can be misdiagnosed as a malignant lesion. | 24445897 |
| Inflammation, Atrial Fibrillation by ECG Finding, myocardial injury | Altered Intercellular Communication | Time course of inflammation, myocardial injury, and prothrombotic response after radiofrequency catheter ablation for atrial fibrillation. | 24446024 |
| Inflammation, Atrial Fibrillation by ECG Finding, Cerebrovascular accident, Atrial Fibrillation, Cardiac Arrhythmia | Altered Intercellular Communication | Inflammation has been linked to the genesis of stroke in atrial fibrillation (AF) and is implicated in early recurrent arrhythmia after AF ablation. | 24446024 |
| Inflammation, Atrial Fibrillation, myocardial injury | Altered Intercellular Communication | We aimed to define the time course of inflammation, myocardial injury, and prothrombotic markers after radiofrequency ablation for AF and its relation to AF recurrence. | 24446024 |
| Inflammation, Chronic disease | Altered Intercellular Communication | Inflammation is an important contributor to the development of chronic diseases. | 24447090 |
| Inflammation, Noncommunicable Diseases, Aortitis | Altered Intercellular Communication | To identify the frequency of immunoglobulin G4 (IgG4)-related aortitis in patients who undergo aorta surgery and are diagnosed by pathology as having chronic aortic inflammation and to compare IgG4-related aortitis with other non-infectious aortitises in terms of clinical characteristics. | 24447903 |
| Communicable Diseases, Primary malignant neoplasm, Acute and chronic inflammation, Atherosclerosis | Altered Intercellular Communication | In total, 41 had chronic aortic inflammation without atherosclerosis, cancer or infection. | 24447903 |
| Acute and chronic inflammation, Aortitis | Altered Intercellular Communication | In patients with chronic aortic inflammation, 7% had IgG4-related aortitis. | 24447903 |
| Hypometabolism, Vascular insufficiency | Altered Intercellular Communication | This suggested a state of hypometabolism and vascular insufficiency along with an inflammatory condition during VaD. | 24448401 |
| Inflammation, Atherosclerosis, Cardiovascular Diseases | Altered Intercellular Communication | Adiponectin could protect against chronic inflammation, atherosclerosis, and cardiovascular diseases. | 24449263 |
| Inflammation, Rheumatoid Arthritis | Altered Intercellular Communication | A novel p53/microRNA-22/Cyr61 axis in synovial cells regulates inflammation in rheumatoid arthritis. | 24449575 |
| Refractory anemias, Inflammation, Rheumatoid Arthritis | Altered Intercellular Communication | We previously showed that Cyr61 acts to promote fibroblast-like synoviocyte (FLS) proliferation and Th17 cell differentiation, suggesting that Cyr61 plays an important role in mediating the joint inflammation and damage in rheumatoid arthritis (RA). | 24449575 |
| Arthritis | Altered Intercellular Communication | Global and locus-specific 5hmC levels and gene expression changes were monitored in normal chondrocytes stimulated with inflammatory cytokines to identify the effect of joint inflammation. | 24449578 |
| Hashimoto Disease, Inflammation | Altered Intercellular Communication | Hashimoto thyroiditis is the most common type of inflammation of the thyroid gland. | 24449727 |
| Inflammation, Acute appendicitis NOS (disorder) | Altered Intercellular Communication | Histological analysis showed acute inflammation consistent with acute appendicitis caused by T. saginata. | 24450232 |
| Inflammation, Hyperkeratosis | Altered Intercellular Communication | In the patients with OLP, the highest correlation was found between the level of hyperkeratosis and WCQ test (b = 0.53; P < 0.000), inflammation and results of BDI test (b = 0.33; P < 0.002), and results of dynia test and STAI test (b = 0.31; P < 0.004). | 24450470 |
| Coronary Aneurysm, vascular inflammations, Clinical Events Domain | Altered Intercellular Communication | Oxidative stress (OS) is related to vascular inflammation possibly, contributing to the development of coronary ectasia (CE). | 24451144 |
| Primary malignant neoplasm, Cardiovascular Diseases, Inflammatory disorder, Diabetes Mellitus | Altered Intercellular Communication | Shift workers are affected by diet- and inflammation-related diseases, including cardiovascular disease, diabetes, and cancer. | 24451608 |
| Inflammation, Dental Plaque | Altered Intercellular Communication | The cumulative plaque score was 19.7%; 83.8% of patients showed normal gingiva, 10.1% displayed mild inflammation, and 6.1% showed moderate inflammation. | 24451866 |
| Neoplasms | Altered Intercellular Communication | The inflammation-based Glasgow prognostic score (GPS) has been demonstrated to be prognostic for various tumors. | 24452408 |
| Inflammation, Pruritus | Altered Intercellular Communication | Biofilm formation by AD-associated staphylococci almost certainly plays a major role in the occlusion of sweat ducts and leads to inflammation and pruritus. | 24452476 |
| CDISC Integrated Basic Data Structure Dataset, Gastrointestinal inflammation | Altered Intercellular Communication | Metallothioneins have been linked to IBDs, but their role in intestinal inflammation is inconclusive. | 24452846 |
| Inflammation, Colitis | Altered Intercellular Communication | Biopsies of patients with active colitis showed infiltration of MT-positive cells in a pattern that correlated with the grade of inflammation. | 24452846 |
| Inflammation, Weight decreased, Colitis | Altered Intercellular Communication | MT knockout mice displayed less severe acute dextran sulphate sodium (DSS)-induced colitis compared to congenic wild-type mice based on survival, weight loss, colon length, histological inflammation and leukocyte infiltration. | 24452846 |
| Inflammatory Bowel Diseases, Inflammation, Colitis | Altered Intercellular Communication | Since antibody blockade of extracellular MT can reduce colitis in mice, MT may act as a danger signal and may represent a novel target for reducing leukocyte infiltration and inflammation in IBD patients. | 24452846 |
| Inflammation, Atherosclerosis, Coronary heart disease, Choline Dehydrogenase, Mitochondrial | Altered Intercellular Communication | Inflammation plays a key role in the pathogenesis of atherosclerosis that is an underlying cause of coronary heart disease (CHD). | 24453409 |
| Inflammation, Choline Dehydrogenase, Mitochondrial | Altered Intercellular Communication | Since the 1990s, some studies have shown an association between H. pylori infection and CHD, which may be mediated by inflammation. | 24453409 |
| Hypernatremia, Inflammation, Fibrosis Assessment, Ischemia | Altered Intercellular Communication | Among the potential stimuli for NP in clinically stable patients are persistent occult fluid overload, wall stress, inflammation, fibrosis, and ischemia. | 24453873 |
| Inflammation | Altered Intercellular Communication | An extensive body of evidence indicates that oxidative stress and inflammation play a central role in the degenerative changes of systemic tissues in aging. | 24454842 |
| Inflammation | Altered Intercellular Communication | Taken together these data suggest a progressive age associated increase in oxidative damage, inflammation and reduced [NAD(H)] in the brain which may be exacerbated by alcohol intake. | 24454842 |
| Inflammation, Lower Urinary Tract Symptoms | Altered Intercellular Communication | Chronic inflammation is considered as one of the contributing mechanisms of lower urinary tract symptoms (LUTS). | 24454896 |
| Inflammation, Urinary Bladder Diseases, Lower Urinary Tract Symptoms | Altered Intercellular Communication | Serum CRP levels are associated with storage LUTS and sensory bladder disorders, suggesting chronic inflammation might play a role in the patients with storage predominant LUTS. | 24454896 |
| Sleeplessness, Bipolar Disorder | Altered Intercellular Communication | The etiology of depressive symptoms associated with the transition to menopause is still unknown; hormonal changes, serotonergic system or insomnia, could be a trigger to depressive symptomatology. | 24456541 |
| Dysplasia, Carcinoma, Transitional Cell, Chronic inflammation | Altered Intercellular Communication | Pathology from the subsequent surgery demonstrated urothelial carcinoma in the retained ureteral segment in 8 patients, dysplasia or atypia in 3 patients, and 1 patient with chronic inflammation. | 24456786 |
| Inflammation, Prediabetes syndrome, Diabetes Mellitus | Altered Intercellular Communication | Vitamin-D supplementation in vitamin-D insufficient/deficient prediabetes individuals is associated with significantly lower progression to diabetes (6/55 vs. 13/49; p=0.04) and higher reversal to normoglycemia (23/55 vs. 10/49; p=0.02), associated with decreased insulin resistance and systemic inflammation (TNFa and IL6). | 24456991 |
| Kidney Failure, Chronic, Inflammation, Malnutrition | Altered Intercellular Communication | Inflammation and malnutrition are important features in patients with ESRD; however, data on changes in these parameters over time are scarce. | 24458074 |
| Inflammation | Altered Intercellular Communication | Although evidence supports a role for inflammation in interstitial cystitis/bladder pain syndrome (IC/BPS), the mechanism remains unknown. | 24458144 |
| Inflammation | Altered Intercellular Communication | Bladder biopsies were obtained from 53 IC/BPS patients and 27 controls, and hematoxylin and eosin staining, immunostaining and Western blotting were performed to detect inflammation, TRPV1-immunoreactive and PGP9.5-immunoreactive nerve fibers, and NGF, respectively. | 24458144 |
| Inflammation | Altered Intercellular Communication | Our study revealed increased severity of inflammation correlated with a higher expression of TRPV1-immunoreactive nerve fibers and NGF in IC/BPS and correlated with clinical symptoms. | 24458144 |
| Inflammation, Venous Invasion | Altered Intercellular Communication | TSP was associated with CSS in patients with stage I-III disease [hazard ratio (HR) 1.84, 95% confidence interval (CI) 1.17-2.92, P = 0.009], independent of age, systemic inflammation, N stage, venous invasion and Klintrup-Makinen score. | 24458470 |
| Inflammation | Altered Intercellular Communication | We hypothesized that the neutrophil/lymphocyte ratio (NLR), thought to be an indirect manifestation of tumor-promoting inflammation, may be associated with response to abiraterone. | 24458472 |
| Inflammation | Altered Intercellular Communication | Our data may help understand the role of systemic inflammation in mCRPC and warrant further research. | 24458472 |
| Hereditary Diseases, Vascular Diseases, Emotional problems | Altered Intercellular Communication | It has been reported in association with vascular problems, inflammatory conditions, inherited diseases, tractional problems, intraocular surgery and medications. | 24459457 |
| Inflammation, Hypertension, CTCAE, Units Of Measure - Siemens | Altered Intercellular Communication | We conclude that MHO is associated with a low inflammation state, and family history of hypertension may play a role in the MHO phenotype. | 24460218 |
| Inflammation, Obesity | Altered Intercellular Communication | A negative association between a marker of bone formation and a marker of gingival inflammation was observed as early as childhood among Caucasian children with a family history of obesity. | 24460774 |
| Inflammation, Hypermetabolism, Cachexia | Altered Intercellular Communication | Cancer cachexia (CC) is a syndrome characterized by wasting of lean body mass and fat, often driven by decreased food intake, hypermetabolism, and inflammation resulting in decreased lifespan and quality of life. | 24462323 |
| Pain Distress Question, Fracture, Complex Regional Pain Syndromes | Altered Intercellular Communication | In the rat fracture model of CRPS, exaggerated sensory and sympathetic neural signaling stimulate keratinocyte and mast cell proliferation, causing the local production of high levels of inflammatory cytokines leading to pain behavior. | 24462502 |
| Inflammation, Electrocardiogram: left ventricle hypertrophy (finding), Hypertrophy, Congestive heart failure | Altered Intercellular Communication | Congestive heart failure is associated with cardiomyocyte hypertrophy, inflammation, and apoptosis, but the role of PKR in left ventricular hypertrophy and the development of congestive heart failure has not been examined. | 24463368 |
| Hypernatremia, Myocarditis, Congestive heart failure | Altered Intercellular Communication | PKR is a maladaptive factor upregulated in hemodynamic overload that contributes to myocardial inflammation, cardiomyocyte apoptosis, and the development of congestive heart failure. | 24463368 |
| Inflammation, Chronic disease | Altered Intercellular Communication | Chronic inflammation has been implicated in the etiology of various chronic diseases. | 24463788 |
| Inflammation, Fibrosis Assessment | Altered Intercellular Communication | Supra-physiological DPDZ nNOS expression significantly reduced myocardial fibrosis, inflammation and apoptosis. | 24463882 |
| Inflammation, Atrial Fibrillation by ECG Finding | Altered Intercellular Communication | Metabolic changes and inflammation could promote or aggravate atrial fibrillation. | 24463922 |
| Inflammation | Altered Intercellular Communication | Chronic inflammation and sustained stress may be involved in the progression of nonculprit lesions in patients with STEMI. | 24463926 |
| Inflammation, Hypertension, CTCAE, Vascular System Injuries | Altered Intercellular Communication | Erythropoietin-induced hypertension and vascular injury in mice overexpressing human endothelin-1: exercise attenuated hypertension, oxidative stress, inflammation and immune response. | 24463938 |
| Tissue damage, Inflammation | Altered Intercellular Communication | Various cytokines activated by the inhalation of coal dust may mediate inflammation and lead to tissue damage. | 24464026 |
| Thyroid carcinoma, Chronic inflammation | Altered Intercellular Communication | The etiopathogenesis of thyroid cancer has not been clearly elucidated although the role of chronical inflammation and the imbalance between pro- and anti-inflammatory cytokines may play a role in the etiology. | 24464184 |
| Inflammation, Non-alcoholic Fatty Liver Disease, Fatty degeneration | Altered Intercellular Communication | OxNASH correlated with NAS and with the individual histologic features of NAFLD, namely, steatosis, inflammation, and ballooning (P < 0.05), with the strongest association being with inflammation [rho (r) 0.40, 95 % confidence interval 0.23, 0.57, P < 0.001]. | 24464211 |
| Clostridium difficile, Gastrointestinal inflammation | Altered Intercellular Communication | Markers of intestinal inflammation have been proposed for inclusion in Clostridium difficile diagnostic algorithms. | 24464697 |
| Gastrointestinal inflammation, Clostridium difficile enteritis | Altered Intercellular Communication | Faecal calprotectin (f-Cp), a sensitive marker of intestinal inflammation, was evaluated for utility in C. difficile diagnosis in the hospital setting. | 24464697 |
| Airway structure, Inflammation | Altered Intercellular Communication | Non-invasive assessment of upper and lower airway infection and inflammation in CF patients. | 24464968 |
| Inflammation, Aortic Stiffness | Altered Intercellular Communication | Acute inflammation reduces flow-mediated vasodilatation and increases arterial stiffness in young healthy individuals. | 24465022 |
| Inflammation | Altered Intercellular Communication | Our results suggest that acute inflammation induced by influenza vaccination did not affect endothelial function in older adults. | 24465022 |
| Inflammation, Organ Dysfunction Scores, Bacterial Infections | Altered Intercellular Communication | During bacterial infections, activated polymorphonuclear leukocytes (PMNs) cause inflammation and organ dysfunction in severely ill patients. | 24465168 |
| Microcirculatory Bed, Inflammation Mediators, Endothelial dysfunction, Cerebral dysfunction | Altered Intercellular Communication | The association with immunological biomarkers, metabolic cerebral dysfunction and microvascular damage suggests a possible endothelial dysfunction of the cerebral microcirculation or a potential inflammation-mediated shift of the neurovascular coupling. | 24465419 |
| Spinal stenosis of lumbar region, Inflammation, Fibrosis Assessment, Hypertrophy | Altered Intercellular Communication | Chronic inflammation and subsequent fibrosis induced by mechanical stress play an important role in ligamentum flavum (LF) hypertrophy and degeneration in patients with lumbar spinal canal stenosis (LSCS). | 24465594 |
| Inflammation, Coronary Artery Disease | Altered Intercellular Communication | Platelet turnover in stable coronary artery disease - influence of thrombopoietin and low-grade inflammation. | 24465602 |
| Inflammation, IL13 gene, Squamous cell carcinoma of the head and neck | Altered Intercellular Communication | By focusing on inflammation, the present study was designed to compare the immune response induced by allergic rhinitis (AR) and head and neck squamous cell carcinoma (HNSCC). | 24466243 |
| Meningioma, Inflammation | Altered Intercellular Communication | Meningiomas with prominent inflammation are traditionally classified as "lymphoplasmacyte-rich meningioma" (LPM). | 24467316 |
| Meningioma | Altered Intercellular Communication | Additionally, plasma cells represented only a minor component in most examples, whereas macrophages predominated, suggesting that "inflammation-rich meningioma" may be a more accurate term. | 24467316 |
| Communicable Diseases, Inflammation | Altered Intercellular Communication | In this prospective study, we investigated whether HD catheters induce inflammation independent of infection. | 24467342 |
| Communicable Diseases, Inflammation | Altered Intercellular Communication | Hemodialysis patients with a catheter have a heightened state of inflammation independent of infection, and thus our study supports the avoidance of catheters and a timely conversion to AVFs with catheter removal. | 24467342 |
| Inflammation | Altered Intercellular Communication | Surgical removal of the tissue altered by inflammation leads to the development of defects of various sizes, often circular from the glans penis to the scrotum. | 24467680 |
| Inflammation, Ulceration, CTCAE, Necrosis | Altered Intercellular Communication | After the application developed severe inflammation with ulceration and necrosis around the penis. | 24467680 |
| Degenerative polyarthritis, Hypernatremia, Obesity, teratologic | Altered Intercellular Communication | Distinct risk factors for the development of osteoarthritis have been described: general, unmodifiable risk factors (age, sex, and genetic makeup), general, modifiable risk factors (obesity and hormonal factors) and local risk factors (prior joint anomalies and joint overload). | 24467954 |
| Inflammation, Fever, CTCAE, Coughing, Acute Coryza, Streptococcal Infections | Altered Intercellular Communication | A five-point score predicting the presence of A/C/G streptococci [FeverPAIN: Fever; Purulence; Attend rapidly (<= 3 days); severe Inflammation; and No cough or coryza] had moderate predictive value (bootstrapped estimates of area under receiver operating characteristic curve: 0.73 cohort 1, 0.71 cohort 2) and identified a substantial number of participants at low risk of streptococcal infection. | 24467988 |
| Hemorrhagic, Inflammation, Lymphoma | Altered Intercellular Communication | Colonoscopy demonstrated hemorrhagic mucosal erosion with partial ulceration, and the subsequent pathological findings at the inflammation site suggested malignant lymphoma histopathology in the colon. | 24468017 |
| Inflammation, Asthma, Thrombophilia | Altered Intercellular Communication | Evidence suggests that statins may decrease inflammation, airway hyperreactivity, and hypercoagulability while improving revascularization mediated by cholesterol-independent pathways. | 24468035 |
| Inflammation, diabetic | Altered Intercellular Communication | While inflammation has been proposed to contribute to the adverse cardiovascular outcome in diabetic patients, the specific pathways involved have not been elucidated. | 24468151 |
| Inflammation, Breast Carcinoma, Fatigue | Altered Intercellular Communication | Yoga's impact on inflammation, mood, and fatigue in breast cancer survivors: a randomized controlled trial. | 24470004 |
| Inflammation, Fatigue | Altered Intercellular Communication | To evaluate yoga's impact on inflammation, mood, and fatigue. | 24470004 |
| Inflammation | Altered Intercellular Communication | Chronic inflammation may fuel declines in physical function leading to frailty and disability. | 24470004 |
| Inflammation, Fatigue | Altered Intercellular Communication | If yoga dampens or limits both fatigue and inflammation, then regular practice could have substantial health benefits. | 24470004 |
| Aggressive course, Inflammation | Altered Intercellular Communication | Cytologic atypia limited to areas of significant acute inflammation may occur in CC and should, in the absence of aggressive stromal invasion, not preclude a diagnosis of CC. | 24470056 |
| Inflammation | Altered Intercellular Communication | Mitochondrial components, including mitochondrial DNA (mtDNA), when released extracellularly, can act as "damage-associated molecular pattern" (DAMP) agents and cause inflammation. | 24470107 |
| Inflammation | Altered Intercellular Communication | Our findings therefore show that circulating mtDNA increases with age, and can significantly contribute to the maintenance of the low-grade, chronic inflammation observed in elderly people. | 24470107 |
| Gout | Altered Intercellular Communication | Myeloid-related proteins 8 and 14 contribute to monosodium urate monohydrate crystal-induced inflammation in gout. | 24470119 |
| Inflammation, Gout | Altered Intercellular Communication | These endogenous TLR-4 ligands released by activated phagocytes contribute to the maintenance of inflammation in gout. | 24470119 |
| Inflammation, Biliary calculi, Cancer of Digestive System | Altered Intercellular Communication | Gallstones and cholecystectomy may be related to digestive system cancer through inflammation, altered bile flux, and changes in metabolic hormone levels. | 24470530 |
| Inflammation, Biliary calculi, Cancer of Digestive System | Altered Intercellular Communication | Gallstones and cholecystectomy may be related to digestive system cancer through inflammation, altered bile flux, and changes in metabolic hormone levels. | 24470530 |
| Inflammation, Autoimmune thyroid disease | Altered Intercellular Communication | The association between selenium and inflammation and the relevance of selenoproteins in follicular thyroid cell physiology have pointed to a putative role of selenoproteins in the pathogenesis of autoimmune thyroid diseases. | 24471570 |
| Arthralgia, Inflammation, CDISC SEND Laboratory Animal Species Terminology | Altered Intercellular Communication | No major clinicopathological differences could be identified between the genospecies, but neural inflammation and arthralgia were seen more often in lesions caused by invasive ospC strains. | 24471698 |
| Myocardial fibrosis, Inflammation, Aortic Valve Stenosis | Altered Intercellular Communication | Association of inflammation, myocardial fibrosis and cardiac remodelling in patients with mild aortic stenosis as assessed by biomarkers and echocardiography. | 24471798 |
| Inflammation, Fibrosis Assessment, Fluid overload | Altered Intercellular Communication | Myocardial fibrosis in mild AS is independently associated with three factors: LV volume overload, aortic valve pressure overload and inflammation. | 24471798 |
| Inflammation, Fibrosis Assessment | Altered Intercellular Communication | Therefore, the impact of anti-AT1R and anti-ETAR Abs on initiation of inflammation and fibrosis was analyzed. | 24472528 |
| Pharyngeal fistula, Inflammation, Esophageal | Altered Intercellular Communication | In all 12 cases, the oesophageal stoma remained stable, without any complications such as pharyngeal fistula or inflammation. | 24472660 |
| Inflammation, Endometriosis | Altered Intercellular Communication | A pathological assessment showed peritoneal tissue with focal dark pigment associated with mild chronic inflammation and deposition of tattoo pigment; there was no evidence of endometriosis in the specimens. | 24473152 |
| Inflammation, physiopathological | Altered Intercellular Communication | Adipose dysfunction resulting from chronic inflammation and impaired adipogenesis has increasingly been recognized as a major contributor to obesity-mediated insulin resistance, but the molecular mechanisms that maintain healthy adipocytes and limit adipose inflammation remain unclear. | 24473437 |
| Inflammation, Diabetes Mellitus, Non-Insulin-Dependent, Obesity | Altered Intercellular Communication | These data suggest that the SK1-S1P axis could be an attractive target for the development of treatments to ameliorate adipose inflammation and insulin resistance associated with obesity and type 2 diabetes. | 24473437 |
| Angle Closure Glaucoma | Altered Intercellular Communication | Inflammation-related cytokines of aqueous humor in acute primary angle-closure eyes. | 24474267 |
| Senile cataract, Angle Closure Glaucoma, Humor | Altered Intercellular Communication | To measure levels of various inflammation-related cytokines in the aqueous humor of patients with acute primary angle-closure (APAC) and senile cataract. | 24474267 |
| Inflammation, Dissection of aorta | Altered Intercellular Communication | Acute aortic dissection (AAD) causes transient inflammation with occasional pleural fluid (PF) accumulation. | 24474442 |
| Inflammation | Altered Intercellular Communication | Peptides genetically selected for NF-kB activation cooperate with oncogene Ras and model carcinogenic role of inflammation. | 24474797 |
| Inflammation, Primary malignant neoplasm | Altered Intercellular Communication | Chronic inflammation is associated with increased cancer risk. | 24474797 |
| Inflammation, Carcinogenesis | Altered Intercellular Communication | This system provides an in vitro model of NF-kB-driven carcinogenesis and suggests that the known carcinogenic effects of inflammation may be at least partially due to NF-kB-mediated abrogation of oncogene-induced senescence. | 24474797 |
| Sepsis, Inflammation | Altered Intercellular Communication | Because interferon-gamma (IFN-g) plays an important role in inflammation, this work assessed IFN-g single nucleotide polymorphism (SNPs) that may be associated with sepsis. | 24475220 |
| Conjunctivitis | Altered Intercellular Communication | To correlate subclinical conjunctival inflammation and trabeculectomy results. | 24475869 |
| Inflammation, Neoplasms | Altered Intercellular Communication | Chronic inflammation plays a role in the mechanism that promotes tumor initiation. | 24475998 |
| Non-Small Cell Lung Carcinoma | Altered Intercellular Communication | This study aimed to investigate the association between recurrence outcome and chronic inflammation-related co-morbidities in early-stage resected NSCLC. | 24475998 |
| Communicable Diseases, Chronic infectious disease | Altered Intercellular Communication | Further research is required to determine whether a TB infection resembles other chronic infections and inflammatory conditions in having a potential to facilitate oncogenesis. | 24476016 |
| Inflammation, Arthrodermataceae | Altered Intercellular Communication | The initial dermatologic examination led to the clinical diagnosis of inflammation of the scalp, while mycological analysis revealed an uncommon dermatophyte agent, Microsporum gypseum, in the culture. | 24476613 |
| Inflammation, Cyclophosphamide/Vincristine/Dacarbazine Regimen | Altered Intercellular Communication | Waist-to-height ratio, inflammation and CVD risk in obese children. | 24476930 |
| Inflammation, Cyclophosphamide/Vincristine/Dacarbazine Regimen, Endothelial dysfunction | Altered Intercellular Communication | To evaluate the association between waist-to-height ratio (WHtR) and specific biomarkers of inflammation, CVD risk and endothelial dysfunction in prepubertal obese children. | 24476930 |
| Inflammation, Cyclophosphamide/Vincristine/Dacarbazine Regimen, Obesity | Altered Intercellular Communication | Our results lead to the hypothesis that changes in biomarker levels of insulin resistance, inflammation and CVD risk before puberty might induce metabolic consequences of obesity in obese children before reaching adulthood. | 24476930 |
| Inflammation, Muscle (organ) | Altered Intercellular Communication | Physical inactivity, inadequate dietary protein, and low-grade systemic inflammation contribute to age-related muscle loss, impaired function, and disability. | 24477043 |
| Presenile dementia, Inflammation, Thrombophilia | Altered Intercellular Communication | We further focused on the role of dementia and cardiovascular risk factors as well as inflammation (C-reactive protein, fibrinogen) and hypercoagulability (fibrin d-dimers, thrombin generation) in these associations. | 24477111 |
| Inflammation, Critical Illness | Altered Intercellular Communication | The critically ill have increased REE according to inflammation defined by CRP. | 24477456 |
| Inflammation, Renal Cell Carcinoma Pathway | Altered Intercellular Communication | Systemic inflammation has been suggested to impact on the prognosis of metastatic renal cell carcinoma (mRCC). | 24477648 |
| Inflammation, Atrial Fibrillation by ECG Finding | Altered Intercellular Communication | Atrial fibrillation is associated with inflammation and oxidative stress. | 24477817 |
| Inflammation, Atrial Fibrillation by ECG Finding, osteoclast activating factor | Altered Intercellular Communication | Carvedilol and N-acetyl cysteine (NAC) combination decreases inflammation, oxidative stress, and postoperative atrial fibrillation (POAF) rates more than metoprolol or carvedilol. | 24477817 |
| Inflammation | Altered Intercellular Communication | Carvedilol plus NAC reduced oxidative stress and inflammation compared with metoprolol and decreased oxidative stress compared with carvedilol. | 24477817 |
| Inflammation, Corneal Endothelial Cell Loss | Altered Intercellular Communication | The association of higher sVCAM-1 levels with decreased survival suggests that targeted therapies to reduce endothelial damage and inflammation may also be beneficial. | 24478166 |
| Intraocular inflammation | Altered Intercellular Communication | Both groups had the highest values of intraocular inflammation at the 1-week postoperative visit, followed by a decline to barely traceable levels at 1 month. | 24479722 |
| Interstitial inflammation, Idiopathic Interstitial Pneumonias, Fibrosis Assessment, Nonspecific interstitial pneumonia, Pneumonia, Interstitial | Altered Intercellular Communication | Nonspecific interstitial pneumonia (NSIP) is a form of idiopathic interstitial pneumonia characterized histologically by varying degrees of interstitial inflammation and fibrosis that are temporally and morphologically homogeneous in comparison with usual interstitial pneumonia (UIP). | 24480140 |
| Inflammation, Mood Disorders, Depression, Bipolar | Altered Intercellular Communication | IFN-alpha-induced increases in glutamate in dACC and basal ganglia are consistent with MRS findings in bipolar depression and suggest that inflammatory cytokines may contribute to glutamate alterations in patients with mood disorders and increased inflammation. | 24481242 |
| Inflammation, Endothelial dysfunction | Altered Intercellular Communication | Markers of inflammation, oxidative stress, and endothelial dysfunction and the 20-year cumulative incidence of early age-related macular degeneration: the Beaver Dam Eye Study. | 24481424 |
| methyldopa, Inflammation, Endothelial dysfunction | Altered Intercellular Communication | OBJECTIVE To examine the relationships of markers of inflammation, oxidative stress, and endothelial dysfunction to the 20-year cumulative incidence of early AMD. | 24481424 |
| Compression of optic nerve, Orbital Pseudotumor | Altered Intercellular Communication | After initial treatment with pulsed intravenous methylprednisolone, followed by rituximab and radiotherapy, there was a marked improvement in orbital inflammation and clinical and radiological improvement in the compressive optic neuropathy. | 24481505 |
| IgG4-Related Sclerosing Disease, Ocular adnexa structure | Altered Intercellular Communication | IgG4-related disease (IgG4-RD) is an inflammatory condition of unknown etiology that can cause tumefactive lesions in a number of tissues and organs, including the orbit and ocular adnexa. | 24481505 |
| Biliary Colic, Cholecystitis, Cholelithiasis | Altered Intercellular Communication | Diagnosis is made on the basis of symptoms of biliary colic in the absence of cholelithiasis and gallbladder inflammation. | 24481806 |
| Inflammation, Carotid Stenosis, Cerebrovascular accident | Altered Intercellular Communication | Plaque inflammation and unstable morphology are associated with early stroke recurrence in symptomatic carotid stenosis. | 24481971 |
| Inflammation, Dental Plaque, Cerebrovascular accident | Altered Intercellular Communication | We aimed to investigate the relationship between early stroke recurrence after initial symptoms and histological features of plaque inflammation and instability in resected carotid plaque. | 24481971 |
| Inflammation, Cerebrovascular accident | Altered Intercellular Communication | On multivariable Cox regression, including OPS macrophage grade (>=3 or <3), age, and severity of stenosis (50%-69% or >=70%), plaque inflammation was the only variable independently predicting stroke recurrence (adjusted hazard ratio, 9; confidence interval, 1.1-70.6; P=0.04). | 24481971 |
| Inflammation, Cerebrovascular accident | Altered Intercellular Communication | Plaque inflammation and other vulnerability features were associated with highest risk of stroke recurrence and may represent therapeutic targets for future stroke prevention trials. | 24481971 |
| Waldenstrom Macroglobulinemia, Fibrosis Assessment | Altered Intercellular Communication | Endoscopic ultrasound biopsy found pancreatic tissue with lymphoplasmacytic inflammation and fibrosis. | 24482076 |
| Inflammation | Altered Intercellular Communication | Steroid-eluting spacers can improve local drug delivery immediately following endoscopic sinus surgery and reduce the recurrence of inflammation warranting systemic corticosteroids. | 24482348 |
| Inflammation, Smoking, Diabetes Mellitus, Obesity, Hypertension, CTCAE | Altered Intercellular Communication | Smoking, diabetes, hypertension, inflammation and obesity explained some but not all of the remaining association. | 24482683 |
| Inflammation, Lymphoplasmacytic Infiltrate, Neoplasms | Altered Intercellular Communication | Only lymphoplasmocytic infiltration differed significantly, with P+ tumors exhibiting more intense inflammation (P = .041). | 24482787 |
| Squamous cell carcinoma of tongue, Inflammation | Altered Intercellular Communication | Despite the limited number of cases, the results of this study suggest that painful OSCCs of the tongue may be associated with more intense inflammation. | 24482787 |
| Coronary Artery Disease | Altered Intercellular Communication | Immunoglobulin G4 (IgG4)-related immuno-inflammation may play a role in the development of coronary artery disease (CAD). | 24482807 |
| Inflammation, Mediastinitis | Altered Intercellular Communication | [A rapidly progressive case of mediastinitis in which the patient developed inflammation of the soft tissue surrounding the pulmonary artery]. | 24483022 |
| Inflammation, Fever, CTCAE, Leukopenia, Thrombocytopenia | Altered Intercellular Communication | The fever persisted for 4 days and, because elevated hepatobiliary enzymes, leukocytopenia and thrombocytopenia were observed, along with chest CT findings of inflammation of the soft tissues surrounding the left pulmonary artery, the patient was admitted for further examination. | 24483022 |
| Cushing Syndrome | Altered Intercellular Communication | Hormonal tests suggested the presence of Cushing's syndrome due to ectopic ACTH production. | 24483161 |
| Inflammation, Observation Method - Coagulation | Altered Intercellular Communication | Parenterally administered ascorbic acid modulates sepsis-induced inflammation and coagulation in experimental animal models. | 24484547 |
| Single organ dysfunction, Inflammation, Endothelium | Altered Intercellular Communication | Intravenous ascorbic acid infusion was safe and well tolerated in this study and may positively impact the extent of multiple organ failure and biomarkers of inflammation and endothelial injury. | 24484547 |
| Inflammation, Primary malignant neoplasm | Altered Intercellular Communication | Chronic inflammation is a major risk factor for the development and metastatic progression of cancer. | 24484937 |
| Nasal Polyps | Altered Intercellular Communication | Decrease in the activity and specific activity concentration of the majority of examined lysosomal exoglycosidases (increasing in inflammations) in comparison to hypertrophic lower nasal conchae suggests electrolytes disorders and questions the inflammatory background of nasal polyps. | 24484945 |
| Inflammation, Dental Plaque, Atherosclerosis | Altered Intercellular Communication | Because they regulate arterial inflammation and are closely related to atherosclerosis and plaque instability, these two mutated genes have become a research hotspot. | 24485247 |
| Presenile dementia, Inflammation, Impaired cognition, Endothelial dysfunction | Altered Intercellular Communication | Low-grade inflammation and endothelial dysfunction are related to cognitive decline and dementia, in a complex interplay with vascular factors and aging. | 24485482 |
| Inflammation, Endothelial dysfunction | Altered Intercellular Communication | We investigated, in an older population, low-grade inflammation and endothelial dysfunction in relation to detailed assessment of cognitive functioning. | 24485482 |
| Inflammation, Endothelial dysfunction, Cardiovascular Diseases | Altered Intercellular Communication | Low-grade inflammation and endothelial dysfunction accounted for only 2.6% explained variance in cognitive functioning, on top of related vascular risk factors and cardiovascular disease. | 24485482 |
| Inflammation, Endothelial dysfunction | Altered Intercellular Communication | Bootstrapping analyses show that low-grade inflammation and endothelial dysfunction mediate the relation between vascular risk factors and cognitive functioning. | 24485482 |
| Inflammation, Endothelial dysfunction | Altered Intercellular Communication | This study shows that low-grade inflammation and endothelial dysfunction contribute to reduced information processing speed and executive functioning in an older population. | 24485482 |
| Inflammation, Immediate hypersensitivity | Altered Intercellular Communication | MCS individuals displayed a distinct systemic immune mediator profile with increased levels of pro-inflammatory cytokines and interleukin-2 and inverse regulation of Th2 associated cytokines interleukin-4 and interleukin-13 suggestive of low-grade systemic inflammation, along with a deviating Th2-associated cytokine response not involving IgE-mediated mechanisms. | 24485486 |
| Granulomatous inflammation, Encephalopathy, CTCAE 5.0, Calcified (qualifier) | Altered Intercellular Communication | At autopsy, multicystic encephalopathy was confirmed with bilateral gliosis, granulomatous inflammation with multinucleated giant cells, and calcifications. | 24485930 |
| Inflammation | Altered Intercellular Communication | However, it was still unclear whether these genital mycoplasmas would contribute to the development of inflammation of the male urethra. | 24486047 |
| Upper Respiratory Infections | Altered Intercellular Communication | Impaired granulocyte PKA function in AERD may lead to dysregulated control of 5-lipoxygenase activity by PGE(2), whereas adherent platelets lead to increased production of LTs, which contributes to the features of persistent respiratory tract inflammation and LT overproduction. | 24486071 |
| Respiration Disorders | Altered Intercellular Communication | Aspirin-exacerbated respiratory disease (AERD) is an inflammatory condition of the respiratory tract and is characterized by overproduction of leukotrienes (LT) and large numbers of circulating granulocyte-platelet complexes. | 24486071 |
| Inflammation, Hypertensive (finding), Corneal Endothelial Cell Loss | Altered Intercellular Communication | The polymorphism rs836478 was associated with an increased expression in markers of inflammation and endothelial damage (MMP9 and IL-6) in pediatric subjects with a hypertensive genetic background. | 24487980 |
| Inflammation | Altered Intercellular Communication | Compared with type A gastric microstructure, types B and C gastric microstructure showed a significantly higher degree of inflammation (P < 0.001). | 24488235 |
| Gastritis | Altered Intercellular Communication | The sensitivity, specificity and accuracy of types B + C microstructure as a predictor of gastric inflammation were 85.4, 81.7 and 83.1 %, respectively. | 24488235 |
| Inflammation | Altered Intercellular Communication | Osteoprotegerin (OPG) may contribute to the link between systemic inflammation and increased cardiovascular risk. | 24488413 |
| Parotid Neoplasms, Inflammation | Altered Intercellular Communication | A retrospective evaluation was carried out for all patients with signs of inflammation in the parotid gland on the ground of a benign parotid tumor, as confirmed by permanent histology. | 24488708 |
| Inflammation, Facial paralysis, Malignant Neoplasms | Altered Intercellular Communication | Diverse clinical signs (inflammation signs, facial palsy), ultrasound and MRI findings (poorly defined lesion margins), and the presence of squamous metaplastic changes on cytology often raised the suspicion of parotid malignancy or abscess. | 24488708 |
| Kidney Diseases, Nephritis | Altered Intercellular Communication | Monocyte chemoattractant protein-1 (MCP-1), which is up regulated in kidney diseases, is considered a marker of kidney inflammation. | 24489972 |
| Salmonella enterica subsp. salamae, Inflammation, Septic Shock, Bacteremia | Altered Intercellular Communication | By multivariate analysis, the major predictors of complicated S. aureus-CLABSI were septic shock, catheter site inflammation, presence of peripherally inserted central catheter, anti-cancer chemotherapy within 10 days, and persistent bacteremia beyond 72 hours (P <= 0.02). | 24491173 |
| Inflammation, HIV-Associated Lipodystrophy Syndrome, Obesity | Altered Intercellular Communication | Inflammation, and specifically adipose tissue (AT) inflammation, is part of the pathophysiology of obesity and HIV-associated lipodystrophy. | 24494803 |
| Refractory anemias, Rheumatoid Arthritis, Arthritis | Altered Intercellular Communication | Rheumatoid synovial fibroblasts (RASFs) mediate joint inflammation and destruction in rheumatoid arthritis (RA). | 24495480 |
| palladium, Inflammation | Altered Intercellular Communication | In addition, inflammation has been proposed as one of the factors contributing to PD pathophysiology. | 24495872 |
| palladium, Inflammation | Altered Intercellular Communication | Although adipokines play important roles in inflammation, it seems that they are not implicated in the inflammatory response associated with PD. | 24495872 |
| Non-Small Cell Lung Carcinoma | Altered Intercellular Communication | No other reproductive or hormonal factor was associated with survival after an NSCLC diagnosis. | 24496005 |
| Benign Paroxysmal Positional Vertigo | Altered Intercellular Communication | Data suggest that hormonal fluctuations (especially during menopause) may increase the tendency to develop BPPV. | 24496089 |
| Inflammation, Obesity | Altered Intercellular Communication | Childhood obesity has recently been linked to low-grade inflammation. | 24497216 |
| Refractory anemias, Inflammation | Altered Intercellular Communication | Composite measures used to assess RA are flawed, as they confound RA inflammation and patient distress, and more consideration should be given to disaggregated assessments. | 24497433 |
| Carcinogenesis, Primary malignant neoplasm | Altered Intercellular Communication | Smoking-related cancer of the respiratory tract was found to affect the expression of genes encoding xenobiotic biotransformation proteins, as well as proteins associated with crucial inflammation/immunity pathways and other processes that protect the airway from the chemicals in cigarette smoke or contribute to carcinogenesis. | 24497500 |
| Inflammation, Malignant neoplasm of endometrium | Altered Intercellular Communication | Inflammation plays an important role in endometrial cancer etiology. | 24500149 |
| Inflammation, Skeletal muscle structure, Dermatomyositis, Childhood Type | Altered Intercellular Communication | Juvenile dermatomyositis (JDM) is a multisystem disease characterized by non-purulent inflammation in the striated muscle and skin. | 24500836 |
| Inflammation, Hypertrophic Cardiomyopathy | Altered Intercellular Communication | Vitamin D deficiency has been associated with the development of myocardial hypertrophy and inflammation. | 24500905 |
| Inflammation, diabetic | Altered Intercellular Communication | In summary, xenogenic transplantation of human SVF did not induce systemic inflammation and successfully improved erectile function in diabetic mice through enhanced penile angiogenesis and neural regeneration. | 24501171 |
| Inflammation, Pterygium Of Conjunctiva And Cornea | Altered Intercellular Communication | Concomitant examination of inflammation and angiogenesis in the pathogenesis of primary moderate pterygium in a well-designed case-control study. | 24502169 |
| Inflammation | Altered Intercellular Communication | Chronic inflammation and angiogenesis are two major proposed mechanisms of the disease in the current literature. | 24502169 |
| Inflammation, Pterygium Of Conjunctiva And Cornea | Altered Intercellular Communication | This study indicates that both inflammation and angiogenesis play pivotal role, in parallel, in pathogenesis of pterygium. | 24502169 |
| Inflammation, Endothelial dysfunction | Altered Intercellular Communication | To investigate whether an adverse body composition is associated with endothelial dysfunction (ED) and the extent to which any such association could be explained by low-grade inflammation (LGI) and/or insulin resistance (HOMA2-IR). | 24503113 |
| Inflammation, Rheumatoid Arthritis | Altered Intercellular Communication | Visualizing inflammation activity in rheumatoid arthritis with Tc-99 m anti-CD4-mAb fragment scintigraphy. | 24503329 |
| Degenerative polyarthritis, Inflammation | Altered Intercellular Communication | The serum level of OPN is correlated with severity of inflammation in the OA patients. | 24503399 |
| ARCN1 gene, Chronic Obstructive Airway Disease, Pneumonitis | Altered Intercellular Communication | To study the association of free immunoglobulin light chain (FLC) with clinical manifestations and lung inflammation in smokers with normal lung function and chronic obstructive pulmonary disease (COPD) patients. | 24503428 |
| HD Term Type, Inflammation | Altered Intercellular Communication | These data suggest that the consumption of only one Brazil nut per day during 3 months was effective to reduce the inflammation, oxidative stress markers, and the atherogenic risk, thereby increasing the antioxidant defenses in HD patients. | 24504745 |
| Gastrointestinal inflammation | Altered Intercellular Communication | The relationship between intestinal inflammation and circulating components of the renin-angiotensin system (RAS) is poorly understood. | 24505094 |
| Compressed structure, Inflammatory abnormality of the eye, Serous retinal detachment, Dystonia, Dopa-Responsive, due to Sepiapterin Reductase Deficiency | Altered Intercellular Communication | To evaluate the effectiveness of silicone oil tamponade in patients with chronic serous retinal detachment (SRD) persisting for three months after the resolution of ocular inflammation. | 24505198 |
| Tuberculosis, Pulmonary, Inflammatory abnormality of the eye, Dystonia, Dopa-Responsive, due to Sepiapterin Reductase Deficiency | Altered Intercellular Communication | A total of 17 eyes of 17 patients diagnosed with chronic SRD persisting for three months after the resolution of ocular inflammation and with high risk of phthisis bulbi by secondary ocular hypotony and macular detachment by subretinal fibrous membrane formation were subjected to surgical intervention. | 24505198 |
| Eye pain, Inflammation | Altered Intercellular Communication | During the first cycle of chemotherapy (cyclophosphamide, doxorubicin, vincristine, and prednisolone), the patient complained of right ocular pain and inflammation. | 24505208 |
| Inflammation, Fibrosis Assessment | Altered Intercellular Communication | The aims of the present study are 1) to determine whether LVM is associated with mortality and various cardiovascular events and 2) to identify determinants of LVM including biomarkers of inflammation and fibrosis. | 24505249 |
| Inflammation, Fibrosis Assessment | Altered Intercellular Communication | No relationship was found between LVM and markers of inflammation and fibrosis. | 24505249 |
| Inflammation, Cardiac dysfunction, Anemia | Altered Intercellular Communication | Low TSAT was a significant independent risk factor for adverse clinical outcome in incident dialysis patients with anemia, which may be partly attributed to cardiac dysfunction and inflammation. | 24505281 |
| Steatohepatitis, Fibrosis Assessment, Hepatitis | Altered Intercellular Communication | Positive correlations were found between liver inflammation and baseline CD4 count, sVCAM and HGF; fibrosis stage and HGF; liver steatosis, BMI and leptin. | 24506344 |
| Pulmonary Emphysema, Pneumonitis | Altered Intercellular Communication | IL-6/Stat3-driven pulmonary inflammation, but not emphysema, is dependent on interleukin-17A in mice. | 24506702 |
| Pulmonary Emphysema | Altered Intercellular Communication | Pulmonary emphysema is linked to T cell-mediated autoimmune inflammation, although the pathogenic role of specific pro-inflammatory cytokines remains unclear. | 24506702 |
| Pulmonary Emphysema, Pneumonitis | Altered Intercellular Communication | We therefore evaluated a causal role for IL-17A in the IL-6-driven gp130(F/F) mouse model for spontaneous pulmonary inflammation and emphysema. | 24506702 |
| Pulmonary Emphysema, Pneumonitis | Altered Intercellular Communication | Importantly, genetic ablation of Il17a in gp130(F/F) : Il17a-/- mice prevented lung inflammation; however, emphysema still developed. | 24506702 |
| Inflammation, Pulmonary Emphysema | Altered Intercellular Communication | Consistent with these findings, augmented IL17A expression was observed in emphysema patients presenting with inflammation compared with inflammation-free individuals. | 24506702 |
| Pulmonary Emphysema, Pneumonitis | Altered Intercellular Communication | Collectively, our data suggest that the integration of IL-17A into the IL-6/Stat3 signalling axis mediates lung inflammation, but not emphysema, and that discrete targeting of IL-17A may alleviate pulmonary inflammatory-related diseases. | 24506702 |
| Inflammation, Hypertension, CTCAE | Altered Intercellular Communication | Inflammation was an important process in the development of hypertension. | 24507232 |
| Inflammation, Hypertensive (finding) | Altered Intercellular Communication | WHtR is a sensitive index associated with chronic inflammation in obese hypertensive subjects. | 24507240 |
| Inflammation, Neoplasms, Gain of Chromosome 8q, Structure of lamina episcleralis, Ocular Melanoma with Extraocular Extension, Loss of Chromosome 3 | Altered Intercellular Communication | Statistical analysis (log-rank test or Cox regression analysis) was performed to correlate MFS with tumor characteristics, extraocular extension, episcleral diameter of the extraocular extension, cell type, extracellular matrix patterns, inflammation, loss of chromosome 3, and gain of chromosome 8q. | 24508790 |
| Inflammation, Atherosclerosis, Kit Ligand, human, Motor Disorders, Endothelial dysfunction | Altered Intercellular Communication | The exact pathophysiology of slow coronary flow (SCF) phenomenon, characterized by delayed opacification of coronary arteries during coronary angiography, is still unknown, although endothelial dysfunction, inflammation, vasomotor disorders and atherosclerosis are shown. | 24509324 |
| Inflammation, Kit Ligand, human, Atherosclerosis | Altered Intercellular Communication | We conclude that SCF phenomenon appears to be associated with enhanced procoagulant state, which may support the role of inflammation and atherosclerosis in the pathogenesis of this phenomenon. | 24509324 |
| Traumatic injury | Altered Intercellular Communication | Trauma stress and neuro-inflammation caused by surgery/anaesthesia releases cytokines. | 24509399 |
| Inflammation, Pain Distress Question | Altered Intercellular Communication | Protease-activated receptors (PARs) are a unique class of receptors which are implicated in mediating inflammation, pain and other functions. | 24509446 |
| Inflammation | Altered Intercellular Communication | The addition of only one marker of inflammation led to an adequate level of significance (ASDAS-CRP, p = 0.0018; ASDAS-ESR, p = 0.003). | 24509896 |
| Inflammation, Peritonitis, Cellulitis, Hernia, Shock | Altered Intercellular Communication | We classified the degree of clinical and bowel morphological changes into 3 grades based on the incarceration time, intestinal morphology after damage, hernia sac integrity, degree of inflammation, and the presence/absence of bacterial growth, peritonitis signs, mechanical obstruction, cellulitis, and systemic shock. | 24509901 |
| Inflammation, NLRP3 gene, Amyloid nephropathy | Altered Intercellular Communication | Our data, though limited to only two patients, emphasize that therapeutic intervention with canakinumab, suppressing both inflammation and IL-1b-mediated manifestations, can contribute to improve kidney function in MWS with overt renal amyloidosis. | 24510061 |
| Inflammation, Observation Method - Coagulation, Osage language | Altered Intercellular Communication | Systemic inflammation and coagulation may be related to cardiovascular pathophysiology in patients with OSA. | 24510497 |
| Inflammation, Cardiovascular Diseases | Altered Intercellular Communication | Fibrinogen is a major coagulation protein associated with inflammation, and long-term elevated plasma fibrinogen is associated with an increased risk of major cardiovascular diseases. | 24510497 |
| Inflammation, Chronic Kidney Diseases, Cardiovascular Diseases | Altered Intercellular Communication | Targeting angiopoietin-2 to attenuate inflammation and collagen expression may provide a novel therapy for cardiovascular disease in CKD. | 24511140 |
| Inflammation, Neoplasms | Altered Intercellular Communication | PDGFs/PDGFRs play critical roles in angiogenesis and possibly in inflammation, and they contribute to the pathogenesis of RN, irrespective of the original tumor pathology and applied radiation modality. | 24512807 |
| Inflammation, Neoplasms | Altered Intercellular Communication | The tumors were consisted of darkly staining basaloid cells and shadow cells, which most cases associated with polynuclear giant cell reaction and chronic inflammation. | 24513001 |
| Inflammation, Neoplasms, Osteogenesis, Calcinosis, Pilomatrixoma | Altered Intercellular Communication | Pilomatrixoma is a benign neoplasm which is mainly consisted of basaloid cells and shadow cells, usually combined with inflammation, foreign body giant cells, calcification and ossification.If a child or young patient has a firm subcutaneous mass in the upper eyelid or eyebrow area, a pilomatrixoma should be suspected. | 24513001 |
| allergic inflammation, "Extra-osseous Ewings sarcoma", Disease | Altered Intercellular Communication | Our observations place iNKT cells at the center of allergic inflammation associated with EoE, which could have profound implications for our understanding, treatment and prevention of this and other human allergic diseases. | 24513807 |
| Inflammation | Altered Intercellular Communication | Poor self-rated health (SRH) and elevated inflammation and morbidity and mortality are robustly associated in middle- and older-aged adults. | 24513874 |
| Rheumatoid Arthritis, Inflammation | Altered Intercellular Communication | Prediction of relapse after discontinuation of biologic agents by ultrasonographic assessment in patients with rheumatoid arthritis in clinical remission: high predictive values of total gray-scale and power Doppler scores that represent residual synovial inflammation before discontinuation. | 24515410 |
| Refractory anemias, Inflammation, Rheumatoid Arthritis | Altered Intercellular Communication | This prospective study aimed to determine whether the comprehensive ultrasonographic assessment of synovial inflammation predicts relapse after discontinuation of treatment with a biologic agent in patients with rheumatoid arthritis (RA) in clinical remission. | 24515410 |
| Refractory anemias, Inflammation | Altered Intercellular Communication | In RA patients in clinical remission receiving treatment with a biologic agent, residual synovial inflammation determined by comprehensive ultrasound assessment predicted relapse within a short term after discontinuation of the treatment. | 24515410 |
| Stomach Carcinoma | Altered Intercellular Communication | Value of preoperative inflammation-based prognostic scores in predicting overall survival and disease-free survival in patients with gastric cancer. | 24515568 |
| Stomach Carcinoma | Altered Intercellular Communication | This study was designed to identify which are the best preoperative inflammation-based prognostic scores in terms of overall survival (OS) and disease-free survival (DFS) in patients with gastric cancer. | 24515568 |
| Inflammation, Pain Distress Question, Muscle damage, Swelling, Actual blood loss | Altered Intercellular Communication | Compared with Groups A and B, both serum inflammation and muscle damage markers were lower in Group C. There were no significant differences between the groups in terms of HSS knee score, ROM, estimated blood loss, swelling ratio, VAS pain score and hospital stays. | 24515866 |
| Intraoperative Blood Salvage, Inflammation, Muscle damage | Altered Intercellular Communication | Using a tourniquet full time in minimally invasive TKA causes less intraoperative blood loss and more excessive inflammation and muscle damage. | 24515866 |
| Inflammation, Granulation finding | Altered Intercellular Communication | Antibiotics have been shown to decrease local inflammation and granulation tissue formation in the trachea. | 24515969 |
| Injury of liver, Hepatitis, Chronic | Altered Intercellular Communication | Recent studies suggest that ongoing chronic liver inflammation is responsible for the liver injury in HCV-infected patients. | 24516541 |
| Communicable Diseases | Altered Intercellular Communication | Compared with uninfected individuals, HCV infection and HCV/HIV-1 coinfection markedly altered expression of 59.5% and 50.0% of 84 inflammation-related genes tested, respectively. | 24516541 |
| Inflammation, Carcinogenesis | Altered Intercellular Communication | Cyclooxygenase-2 (COX-2) is a key enzyme in the conversion of arachidonic acid to prostanoids, and its activation is associated with carcinogenesis as well as inflammation. | 24516579 |
| Autoimmune Diseases, Inflammation, Cholestanes, Primary Biliary Cholangitis | Altered Intercellular Communication | Primary biliary cirrhosis (PBC) is a chronic cholestatic, autoimmune, liver disease produced by inflammation and destruction of the interlobular bile ducts. | 24516954 |
| Inflammation, Atrophic | Altered Intercellular Communication | Although the inflammation was reduced after treatment, atrophy of the ganglion cells continuted to progress. | 24516982 |
| Inflammation, Impaired | Altered Intercellular Communication | TNFa is suspected to play a role in inflammation and insulin resistance leading to higher risk of metabolic impairment. | 24517151 |
| Heterotopic Ossification, Malignant Childhood Neoplasm | Altered Intercellular Communication | Inactivating mutation of the GNAS gene is associated with several diseases, which commonly manifest heterotopic ossification and hormonal resistance; however, the development of malignant neoplasm has never been reported. | 24517547 |
| Inflammation, Fever, CTCAE | Altered Intercellular Communication | Because her fever and inflammation persisted, therapeutic cholecystectomy was performed. | 24517554 |
| Inflammation, Sleep Apnea, Obstructive, HIV Infections | Altered Intercellular Communication | Association between systemic inflammation and obstructive sleep apnea in men with or at risk for HIV infection. | 24518040 |
| Human immunodeficiency virus (HIV) status, Inflammation, Sleep Apnea, Obstructive, Osage language | Altered Intercellular Communication | We sought to determine whether markers of systemic inflammation are associated with the presence of moderate/severe obstructive sleep apnea (OSA) and whether this association differs based on HIV and HIV treatment status. | 24518040 |
| Inflammation | Altered Intercellular Communication | Compared with HIV+/HAART men and HIV- men, markers of systemic inflammation were higher in HIV+/no HAART men. | 24518040 |
| Inflammation, Weight decreased | Altered Intercellular Communication | Iron status and inflammation were improved by weight reduction. | 24518166 |
| Inflammation, Head of pancreas, Stricture of bile duct | Altered Intercellular Communication | Both pancreatic head swelling and IgG4-related biliary inflammation affect lower bile duct stricture, which may be included in IgG4-related sclerosing cholangitis. | 24518505 |
| Inflammation, Dysplasia | Altered Intercellular Communication | MACC1 overexpression (H-score >100) was seen in 67% of conventional CAC but in 0% of dysplasia and 0% of inflammation or normal colon. | 24518605 |
| methionine, Dysplasia, Inflammation | Altered Intercellular Communication | MET expressions in inflammation, dysplasia, and conventional CAC were statistically similar. | 24518605 |
| Inflammation, Disease remission | Altered Intercellular Communication | T2, T1Gad SIRs and n-ADC of EOMs were compared in patients with active inflammation, those with inactive disease and 26 healthy controls, and correlated with clinical scores. | 24519110 |
| Acute inflammation | Altered Intercellular Communication | Dexamethasone intravitreal implant to control postoperative inflammation may take several days until it achieves high concentrations in the vitreous. | 24519510 |
| Inflammation, Breast Carcinoma | Altered Intercellular Communication | Systemic inflammation among breast cancer survivors: the roles of goal disengagement capacities and health-related self-protection. | 24519882 |
| Inflammation, Breast Carcinoma | Altered Intercellular Communication | The study's findings suggest that goal disengagement capacities and health-related self-protection can work together in predicting systemic inflammation among breast cancer survivors. | 24519882 |
| Airway structure, Ulcerative Colitis | Altered Intercellular Communication | The A1AT level in the serum and the colon tissue obviously decreased in UC patients, indicating the pulmonary function impairment of UC patients might manifest as decreased A1AT levels correlated chronic airway inflammation, remodeling of airway, and obstructive changes. | 24520781 |
| Inflammation, Dental Occlusion, Traumatic | Altered Intercellular Communication | This indicates the need to continuously monitor risk factors, including inflammation and traumatic occlusion, during SPT. | 24521550 |
| Refractory anemias | Altered Intercellular Communication | This Treg subset with Th17 plasticity in peripheral blood retained suppressive functions and was associated with milder inflammatory conditions, suggesting that this Treg population works as a negative regulator in RA, but in RA synovial site it may be pathogenic. | 24521740 |
| Inflammation, Psoriasis, Inflammatory dermatosis | Altered Intercellular Communication | Psoriasis is a chronic inflammatory skin disease and various stress factors mediate inflammation. | 24521827 |
| Inflammation | Altered Intercellular Communication | HSP90 from keratinocytes and mast cells is a key regulator of psoriatic inflammation and HSP90 inhibitors may represent a novel therapeutic approach to the disease. | 24521827 |
| Inflammation, Hypoxia, Lung | Altered Intercellular Communication | Application of continuous positive airway pressure (CPAP) to the collapsed lung potentially reduces pulmonary damage, hypoxia, and consequent inflammation. | 24523436 |
| Inflammation | Altered Intercellular Communication | Tertiary lymphoid tissue (TLT) is an ectopic organized lymph node-like structure that typically forms at sites of chronic inflammation and is involved in adaptive immune responses. | 24523438 |
| Inflammation, Osteoporosis, Postmenopausal | Altered Intercellular Communication | Recent studies revealed that inflammation plays a critical role in bone remodeling and the pathogenesis of postmenopausal osteoporosis, a major health concern. | 24524373 |
| Inflammation | Altered Intercellular Communication | Neutrophil-lymphocyte ratio (NLR) is a cost-effective marker of inflammation that has been linked with several diseases. | 24524373 |
| Steatohepatitis, Fibrosis Assessment, Inflammation | Altered Intercellular Communication | A serum AIM level of >= 1.2 mg/ml was independently associated with advanced hepatic fibrosis (F2 or F3) (odds ratio [OR], 5.612; 95% confidence interval [CI], 1.103-28.563; P = 0.038) based on a multivariate analysis, but there was no significant association between AIM and hepatic steatosis or inflammation. | 24524410 |
| Steatohepatitis, Fibrosis Assessment, Inflammation | Altered Intercellular Communication | Furthermore, a serum leptin level of >= 8.6 ng/ml was independently associated with the presence of hepatic steatosis (>= 5%) (OR, 6.195; 95% CI, 1.409-27.240; P = 0.016), but not hepatic fibrosis or inflammation. | 24524410 |
| Communicable Diseases, Inflammation | Altered Intercellular Communication | Leptin (LPT), a hormone secreted by adipocytes,plays a role in inflammation and infection. | 24524473 |
| Communicable Diseases, Inflammation | Altered Intercellular Communication | Leptin (LPT), a hormone secreted by adipocytes,plays a role in inflammation and infection. | 24524473 |
| Asthma, Eosinophilic inflammation | Altered Intercellular Communication | Concomitant systemic and bronchial eosinophilic inflammation contribute to poor asthma control. | 24525441 |
| Inflammation, Mycobacterium Infections | Altered Intercellular Communication | A biopsy of granulation tissue obtained from the right external auditory canal demonstrated chronic inflammation that was suggestive of mycobacterial infection. | 24526478 |
| vascular inflammations, Endothelial dysfunction, Atherosclerosis | Altered Intercellular Communication | Role of endothelial cell-derived angptl2 in vascular inflammation leading to endothelial dysfunction and atherosclerosis progression. | 24526691 |
| vascular inflammations, Atherosclerosis | Altered Intercellular Communication | Efforts to develop effective therapeutic strategies have focused on vascular inflammation as a critical pathology driving atherosclerosis progression. | 24526691 |
| vascular inflammations, Atherosclerosis | Altered Intercellular Communication | Here, we ask whether angiopoietin-like protein 2 (Angptl2), a proinflammatory protein, contributes to vascular inflammation that promotes atherosclerosis progression. | 24526691 |
| vascular inflammations, Atherosclerosis | Altered Intercellular Communication | Angptl2 knockout in apolipoprotein E-deficient mice (ApoE(-/-)/Angptl2(-/-)) attenuated atherosclerosis progression by decreasing the number of macrophages infiltrating atheromatous plaques, reducing vascular inflammation. | 24526691 |
| vascular inflammations, Dental Plaque | Altered Intercellular Communication | Conversely, ApoE(-/-) mice crossed with transgenic mice expressing Angptl2 driven by the Tie2 promoter (ApoE(-/-)/Tie2-Angptl2 Tg), which drives Angptl2 expression in endothelial cells but not monocytes/macrophages, showed accelerated plaque formation and vascular inflammation because of increased numbers of infiltrated macrophages in atheromatous plaques. | 24526691 |
| vascular inflammations, Endothelial dysfunction, Atherosclerosis | Altered Intercellular Communication | Endothelial cell-derived Angptl2 accelerates vascular inflammation by activating proinflammatory signaling in endothelial cells and increasing macrophage infiltration, leading to endothelial dysfunction and atherosclerosis progression. | 24526691 |
| Cataract, Inflammation | Altered Intercellular Communication | Are increased levels of systemic oxidative stress and inflammation associated with age-related cataract? | 24527727 |
| Cataract, Inflammation | Altered Intercellular Communication | Oxidative stress and inflammation may be involved in the etiology of age-related cataract. | 24527727 |
| Inflammation | Altered Intercellular Communication | These results may support a role of cell-mediated inflammation in bone metabolism. | 24528145 |
| Inflammation, Calcified (qualifier), Aortic Valve Stenosis, Atherosclerosis | Altered Intercellular Communication | The role of inflammation in fibrotic and calcific processes of atherosclerosis and aortic stenosis (AS) is similar. | 24528173 |
| Inflammation, Heart failure | Altered Intercellular Communication | Furthermore, a relationship between systemic inflammation and heart failure has been well demonstrated. | 24528173 |
| Inflammation | Altered Intercellular Communication | Recently, neutrophil/lymphocyte ratio (NLR) has been proposed as a predictive marker of systemic inflammation. | 24528173 |
| Inflammation, Primary malignant neoplasm | Altered Intercellular Communication | Netrin-1 and its receptor UNC5B play important roles in angiogenesis, embryonic development, cancer and inflammation. | 24528886 |
| Inflammation | Altered Intercellular Communication | Chemerin and interleukin (IL)-8 are pro-inflammatory mediators whose role in joint inflammation and cartilage degradation has been demonstrated in in-vitro findings. | 24529071 |
| ARCN1 gene, Inflammation, Chronic Obstructive Airway Disease | Altered Intercellular Communication | T-lymphocytes, including Th17-cells and T-cells expressing acetylcholine (ACh), are key components of systemic inflammation in chronic obstructive pulmonary disease (COPD). | 24529390 |
| ARCN1 gene, Inflammation | Altered Intercellular Communication | We concluded that ACh might promote the increased levels of Th17-cells in systemic inflammation of COPD. | 24529390 |
| Gliosis, Depressive disorder, Dopamine Measurement | Altered Intercellular Communication | These genes are involved in different aspects of the inflammatory and immune response, oxidative stress, cell cycle activation and/or DNA repair, apoptosis, cytoskeleton reorganization and/or astrogliosis, synaptic plasticity and/or neurotransmission, and depressive disorders and/or dopamine-, serotonin-, GABA-signaling. | 24529500 |
| Inflammation, "Alzheimers Disease | Altered Intercellular Communication | Resolution of inflammation is altered in Alzheimer's disease. | 24530025 |
| Inflammation, "Alzheimers Disease", Data types - Address, Failure (biologic function) | Altered Intercellular Communication | Failure may lead to chronic inflammation, which is known as part of the pathology in the brain of individuals with Alzheimer's disease (AD). | 24530025 |
| Inflammation | Altered Intercellular Communication | These data indicate that the alteration of Th1/Th2/Th17/Treg paradigm exists in T2DN patients, which may contribute to the enhanced immune activation and inflammation, and subsequent development and progression of T2DN. | 24530745 |
| Inflammation, AUTONOMIC NERVOUS SYSTEM DYSFUNCTION | Altered Intercellular Communication | Some of the inflammation markers and autonomic nervous system dysfunction were also independently correlated with carotid IMT increase. | 24530790 |
| Inflammation, Depression, CTCAE, Choline Dehydrogenase, Mitochondrial | Altered Intercellular Communication | Depression symptoms are independently associated with an accelerated progression of carotid IMT in subjects with CHD risk factors, and inflammation may substantially modulate the association between depression and carotid IMT progression. | 24530790 |
| Inflammation, Chronic heart failure | Altered Intercellular Communication | Inflammation is associated with progression of chronic heart failure (HF). | 24530944 |
| Inflammation, Family history | Altered Intercellular Communication | Our findings may implicate a pathogenic role for inflammation and TNF related molecules in FH, and these findings suggest the possibility that novel treatment modalities beyond that of statins and lipid lowering drugs may be useful in FH subjects. | 24530965 |
| Inflammation, Communicable Diseases, Edema, Conjunctivitis, Dysuria, meatitis | Altered Intercellular Communication | We describe two cases showing that adenoviral infection should be reasonably hypothesized in men with dysuria and scant urethral discharge in addition to meatus inflammation and/or edema (meatitis) or conjunctivitis. | 24531179 |
| Inflammation | Altered Intercellular Communication | Scant urethral mucoid secretions, severe meatal inflammation of the male patient were revealed during physical examination. | 24531179 |
| Inflammatory abnormality of the eye, Uveitis | Altered Intercellular Communication | The role of methotrexate in resolving ocular inflammation after specific therapy for presumed latent syphilitic uveitis and presumed tuberculosis-related uveitis. | 24531737 |
| Intraocular inflammation | Altered Intercellular Communication | No recurrence of intraocular inflammation was observed in 6 months to 18 months of follow-up period after cessation of MTX. | 24531737 |
| Intraocular inflammation, Macular Edema, Cystoid, Uveitis | Altered Intercellular Communication | Two eyes of two patients with presumed tuberculosis-related uveitis showed improved best-corrected visual acuity, suppression of intraocular inflammation, and resolution of cystoid macular edema after intravitreal injections of MTX. | 24531737 |
| Intraocular inflammation, Macular retinal edema, Uveitis | Altered Intercellular Communication | For the first time in the treatment of presumed latent syphilitic uveitis and presumed tuberculosis-related uveitis, we believe that MTX might have an adjunctive role to suppress intraocular inflammation, reduce uveitic macular edema, and prevent the recurrences of the diseases. | 24531737 |
| Inflammation, Glomerulitis (disorder) | Altered Intercellular Communication | Microcirculation inflammation, particularly glomerulitis, irrespective of C4d, is associated with a high risk of development of TxGN at 1 year. | 24531821 |
| Inflammation | Altered Intercellular Communication | All these conditions cause inflammation and oxidative stress. | 24531854 |
| Inflammation, PTEN gene, Corneal Endothelial Cell Loss | Altered Intercellular Communication | The results of this study indicate an increased inflammation, endothelial damage, and oxidative stress in PTE. | 24531854 |
| Sacroiliitis, Inflammation | Altered Intercellular Communication | Degree of inflammation was accessed by spondylopathy, sacroiliitis as well as acute phase reactant, erythrocyte sedimentation rate and C-reactive protein (CRP). | 24532142 |
| ARCN1 gene, Inflammation, Impaired cognition, Anxiety, CTCAE 3.0, Chronic Obstructive Airway Disease, Asthma | Altered Intercellular Communication | Depressiveness, symptoms of anxiety and cognitive dysfunctions in patients with asthma and chronic obstructive pulmonary disease (COPD): possible associations with inflammation markers: a pilot study. | 24532256 |
| Pneumonitis | Altered Intercellular Communication | Cathepsin G degradation of phospholipid transfer protein (PLTP) augments pulmonary inflammation. | 24532668 |
| ARCN1 gene, Inflammation, Chronic Obstructive Airway Disease | Altered Intercellular Communication | Since PLTP expression is increased in chronic obstructive pulmonary disease (COPD), this study aimed to determine how PLTP affects lung signaling and inflammation. | 24532668 |
| Airway structure, ARCN1 gene, Chronic Obstructive Airway Disease | Altered Intercellular Communication | Airway inflammation persists after smoking cessation in established chronic obstructive pulmonary disease (COPD), suggesting that other factors drive the airway inflammatory response. | 24532969 |
| Airway structure | Altered Intercellular Communication | This is associated with a reduction in neutrophilic airway inflammation in patients with high bacterial loads. | 24532969 |
| Inflammation | Altered Intercellular Communication | Conversely, age could contribute to the inflammation found in old individuals by increasing the percentage of cells producing pro-inflammatory cytokines. | 24533103 |
| Metabolic Syndrome X | Altered Intercellular Communication | Serum immunoglobulin M concentration is positively related to metabolic syndrome in an adult population: Tianjin Chronic Low-Grade Systemic Inflammation and Health (TCLSIH) Cohort Study. | 24533139 |
| Inflammation, Metabolic Syndrome X, Cardiovascular Diseases | Altered Intercellular Communication | Persistent low-grade systemic inflammation has been increasingly recognized as a common pathological process, and an important contributing factor to cardiovascular diseases and its risk factor, metabolic syndrome. | 24533139 |
| Polymyositis, Skeletal muscle structure, Inflammation, Myositis | Altered Intercellular Communication | Polymyositis (PM) is an inflammatory muscle disease characterized by chronic inflammation in skeletal muscle. | 24533547 |
| Inflammation, Pustulosis of Palms and Soles, Acne, Synovitis, Osteitis, Sapho, Hyperostosis | Altered Intercellular Communication | Severe inflammation associated with synovitis, acne, pustulosis, hyperostosis, osteitis (SAPHO) syndrome was markedly ameliorated by single use of minocycline. | 24533553 |
| Inflammation, Synovitis | Altered Intercellular Communication | Ultrasonographic examination of the joints revealed synovitis and inflammation by B mode and power Doppler ultrasonography. | 24533558 |
| Inflammation | Altered Intercellular Communication | Peripheral inflammation acutely impairs human spatial memory via actions on medial temporal lobe glucose metabolism. | 24534013 |
| Neurodegenerative Disorders | Altered Intercellular Communication | Inflammation impairs cognitive performance and is implicated in the progression of neurodegenerative disorders. | 24534013 |
| Inflammation, BDI - Functional Impairment | Altered Intercellular Communication | These data demonstrate acute sensitivity of human MTL to mild peripheral inflammation, giving rise to associated functional impairment in the form of reduced spatial memory performance. | 24534013 |
| Neurodegenerative Disorders, Inflammation, "Alzheimers Disease | Altered Intercellular Communication | Our findings suggest a mechanism for the observed epidemiologic link between inflammation and risk of age-related cognitive decline and progression of neurodegenerative disorders including Alzheimer's disease. | 24534013 |
| Inflammation, Endotoxemia | Altered Intercellular Communication | Defective autophagy increases mortality and lung inflammation after endotoxemia. | 24535031 |
| Gastroesophageal reflux disease, Inflammation, Idiopathic Pulmonary Fibrosis | Altered Intercellular Communication | We aimed to investigate differences between pH measured directly in the lung, and biomarkers of acute inflammation in patients with newly diagnosed IPF and in patients with newly diagnosed GERD. | 24535066 |
| Nausea, Fatigue, Inflammatory disease of mucous membrane, Anorexia | Altered Intercellular Communication | They mainly consisted of gastrointestinal and general symptoms, such as fatigue, anorexia, mucosal inflammation or nausea. | 24535315 |
| Inflammation, Inflammatory disorder | Altered Intercellular Communication | Enthesopathies are frequently found in rheumatic inflammatory diseases, but can be observed also in absence of systemic inflammation. | 24535409 |
| Liver carcinoma | Altered Intercellular Communication | The inflammation-based scores to predict prognosis of patients with hepatocellular carcinoma after hepatectomy. | 24535607 |
| Malignant neoplasm of liver, Inflammation, Primary malignant neoplasm | Altered Intercellular Communication | The association of inflammation scores with clinicopathological variables and overall survival (OS) was analyzed, and the concordance index (C-index) was calculated to compare the predictive ability of each inflammation scores and staging systems including Barcelona Clinic Liver Cancer (BCLC) and Cancer of the Liver Italian Program (CLIP) scores. | 24535607 |
| Inflammation, Neoplasms | Altered Intercellular Communication | All inflammation scores, except PNI, were associated with tumor size, major/microvascular invasion and clinical stages, and the GPS and mGPS had a higher C-index (0.608). | 24535607 |
| Inflammation, FAM126A gene | Altered Intercellular Communication | The prognostic ability of the GPS is superior to other inflammation scores for patients undergoing hepatectomy as initial treatment for HCC. | 24535607 |
| Inflammation, Stricture of artery | Altered Intercellular Communication | FDG uptake occurred in areas of significant arterial stenosis, irrespective of the degree of inflammation. | 24536009 |
| Fibrosis Assessment, Interstitial inflammation | Altered Intercellular Communication | Serum connective tissue growth factor levels were negatively associated with estimated glomerular filtration rate (r = -0.46, p<0.001) and positively associated with interstitial inflammation (r = 0.309, p = 0.002) and interstitial fibrosis (r = 0.287, p = 0.004). | 24536044 |
| Inflammation, Coronary microvascular dysfunction, Lung Diseases, Obstructive, Obesity | Altered Intercellular Communication | Systemic inflammation is related to coronary microvascular dysfunction in obese patients without obstructive coronary disease. | 24548662 |
| Inflammation, Obesity | Altered Intercellular Communication | Obesity, systemic inflammation and changes in the heart functions are associated with increased cardiovascular risk. | 24548662 |
| Inflammation, physiopathological | Altered Intercellular Communication | This microvascular dysfunction seems to be related to a chronic inflammation mediated by adipocytokines. | 24548662 |
| Inflammation, Asthma | Altered Intercellular Communication | The complex relationship between inflammation and lung function in severe asthma. | 24549277 |
| Airway structure, Inflammation, Asthma, Respiratory Hypersensitivity | Altered Intercellular Communication | Airway inflammation is thought to contribute to asthma pathogenesis, but the direct relationship between inflammation and airway hyperresponsiveness (AHR) remains unclear. | 24549277 |
| Inflammation, Chronic Obstructive Airway Disease | Altered Intercellular Communication | This study investigates the role of inflammation in a steroid-insensitive, severe allergic airway disease model and in severe asthmatics stratified by inflammatory profile. | 24549277 |
| Tumor necrosis, Asthma, Pneumonitis | Altered Intercellular Communication | First, we used the T-helper (T(H))-17 cells adoptive transfer mouse model of asthma to induce pulmonary inflammation, which was lessened by tumor necrosis factor (TNF)-a neutralization or neutrophil depletion. | 24549277 |
| Inflammation | Altered Intercellular Communication | Overall, this work suggests that lung compliance may be linked with cellular inflammation in the airspace, whereas T-cell-driven AHR may be associated with tissue inflammation and other pulmonary factors. | 24549277 |
| Inflammation, FBN2 wt Allele | Altered Intercellular Communication | Inflammation is known to be a risk factor for CCA development, and we tested whether this might induce Wnt/b-catenin signaling. | 24549785 |
| Autoimmune Diseases, Arthritis | Altered Intercellular Communication | Our data clearly show that smoking can change gene expression in the joints, which can lead to the activation of signalling pathways that promote development of autoimmunity and chronic joint inflammation. | 24550170 |
| Inflammation, Albuminuria, Chronic Kidney Diseases, Diabetes Mellitus | Altered Intercellular Communication | Association of race/ethnicity, inflammation, and albuminuria in patients with diabetes and early chronic kidney disease. | 24550221 |
| Inflammation, Chronic Kidney Diseases | Altered Intercellular Communication | Inflammation plays a critical role in the pathogenesis of diabetes-related CKD. | 24550221 |
| Inflammation, Tissue Adhesions | Altered Intercellular Communication | Various foot fillet flaps may be used acutely as a free or an island pedicled flap, but dissection of the vascular pedicle may be difficult in a chronically inflamed wound because of inflammation and adhesions to surrounding tissue. | 24550664 |
| Inflammation, Edema | Altered Intercellular Communication | Significant differences were found when comparing the degree of inflammation with nuclear alterations (p=0.001) and the same results when comparing the degree of edema and nuclear changes (p<0.001). | 24551281 |
| Inflammation, Edema | Altered Intercellular Communication | In clinics the predisposition of female patients to greater degree of edema and inflammation should be accounted for. | 24551281 |
| Hiccough | Altered Intercellular Communication | It is hypothesized that having both GABA and phenylethylamine properties activates inhibitory neurotransmitters, most notably GABA, which may in turn block the hiccup stimulus. | 24551889 |
| Pericarditis, CTCAE, Disorder of pericardium, Myocarditis, Compressed structure | Altered Intercellular Communication | Effusive-constrictive pericarditis, an uncommon pericardial syndrome, is characterized by simultaneous pericardial inflammation and tamponade. | 24552226 |
| Inflammation, Prostate carcinoma | Altered Intercellular Communication | The EPICAP study will particularly focused on the role of circadian disruption, chronic inflammation, hormonal and metabolic factors in the occurrence of prostate cancer. | 24552491 |
| Inflammation, Prostate carcinoma | Altered Intercellular Communication | The EPICAP study will particularly focused on the role of circadian disruption, chronic inflammation, hormonal and metabolic factors in the occurrence of prostate cancer. | 24552491 |
| Breast Carcinoma | Altered Intercellular Communication | Consistent findings across case-control and cohort investigations, complemented by pooled analyses, indicated important roles for anthropometric and hormonal risk factors in the etiology of male breast cancer. | 24552677 |
| Tumor necrosis, Heat-Shock Response, Gastrointestinal inflammation | Altered Intercellular Communication | Targeted inhibition of heat shock protein 90 suppresses tumor necrosis factor-a and ameliorates murine intestinal inflammation. | 24552830 |
| Inflammation, Heat-Shock Response, Gastrointestinal inflammation | Altered Intercellular Communication | Given the critical role of the heat shock response in regulating inflammation, this study proposed to define the impact of selective inhibition of heat shock protein 90 (HSP90) on intestinal inflammation. | 24552830 |
| Inflammation | Altered Intercellular Communication | Peritoneal dialysis patients present chronic inflammation and Th1/Th2 imbalance, but the role of the Th17 response in peritoneal membrane damage has not been investigated. | 24552849 |
| Inflammation, Fibrosis Assessment | Altered Intercellular Communication | Studies in mice showed that repeated exposure to recombinant IL-17A caused peritoneal inflammation and fibrosis. | 24552849 |
| Inflammation, Fibrosis Assessment | Altered Intercellular Communication | IL-17A neutralization diminished experimental peritoneal inflammation and fibrosis caused by chronic exposure to dialysis fluids in mice. | 24552849 |
| Inflammation, Arthropathy associated with infection, Communicable Diseases, Postoperative infection, Infection, Urinary tract infection | Altered Intercellular Communication | The types of postoperative infection were recorded and included lower or upper respiratory tract and lung infection, bone and joint infection, wound inflammation or infection, urinary tract infection, and other infections. | 24553882 |
| Inflammation | Altered Intercellular Communication | These data provide evidence that asymptomatic HSV-2 shedding contributes to chronic inflammation throughout the genital tract. | 24554666 |
| Inflammation | Altered Intercellular Communication | These findings suggest that widespread asymptomatic genital HSV-2 shedding is associated with a targeted host immune response and contributes to chronic inflammation throughout the genital tract. | 24554666 |
| Acute cholecystitis without calculus, Inflammation, Peritonitis | Altered Intercellular Communication | Ultrasonic versus standard electric dissection in laparoscopic cholecystectomy in patients with acute calculous cholecystitis, complicated by peritonitis: influence on the postoperative systemic inflammation and immune response. | 24555909 |
| Bacteremia, Inflammation, Biliary peritonitis, Ulcerative Colitis | Altered Intercellular Communication | Laparoscopic cholecystectomy after biliary peritonitis, conducted by ELC, increased the incidence of bacteremia and systemic inflammation compared with the UC group. | 24555909 |
| Sepsis, Inflammation | Altered Intercellular Communication | Early enhanced postoperative systemic inflammation may cause lower transient immunologic defense in the ELC group, leading to enhanced sepsis. | 24555909 |
| Chikungunya Fever | Altered Intercellular Communication | Inflammation of the external ear in acute chikungunya infection: Experience from the outbreak in Johor Bahru, Malaysia, 2008. | 24556566 |
| Inflammation, Feeling calm | Altered Intercellular Communication | Although cytological atypia of the melanocytes is not sufficient to ALM in situ, the melanocytic proliferation pattern, dermal inflammation, and correlation with clinical presentation would suffice in making the correct diagnosis of ALM in situ. | 24556899 |
| Sjogrens Syndrome", Inflammation | Altered Intercellular Communication | Chronic inflammation enhances NGF-b/TrkA system expression via EGFR/MEK/ERK pathway activation in Sjogren's syndrome. | 24557415 |
| Inflammation, Stomach Carcinoma | Altered Intercellular Communication | Inflammation, especially the cytokine response of the IL-1 family, has been shown to influence susceptibility to gastric cancer. | 24557417 |
| Inflammation, Stomach Carcinoma | Altered Intercellular Communication | Lysyl-tRNA synthetase (KRS) expression in gastric carcinoma and tumor-associated inflammation. | 24558064 |
| Inflammation, Stomach Carcinoma | Altered Intercellular Communication | KRS-related inflammation can be identified in a subset of gastric cancer. | 24558064 |
| ARCN1 gene, Inflammation | Altered Intercellular Communication | Air pollution and biomarkers of systemic inflammation and tissue repair in COPD patients. | 24558180 |
| ARCN1 gene, Inflammation, Chronic Obstructive Airway Disease | Altered Intercellular Communication | The origin(s) of systemic inflammation in patients with chronic obstructive pulmonary disease (COPD) is unclear. | 24558180 |
| ARCN1 gene, Inflammation | Altered Intercellular Communication | These results show that exposure to ambient NO2 increases systemic inflammation in COPD patients, especially in former smokers. | 24558180 |
| Inflammation | Altered Intercellular Communication | Interleukin-17-producing CD4+ effector memory T (Th17) cells and CD4+CD25+Foxp3 regulatory T (Treg) cells both play critical roles in immune activation and inflammation. | 24558316 |
| ARCN1 gene, Airway structure, Communicable Diseases, Fibrosis Assessment, Chronic Obstructive Airway Disease | Altered Intercellular Communication | In human airways diseases, including cystic fibrosis (CF) and chronic obstructive pulmonary disease (COPD), host defense is compromised and airways inflammation and infection often result. | 24558372 |
| Pain Distress Question, Inflammation, Rheumatoid Arthritis, Depression, CTCAE, Inflammatory disorder, Fatigue | Altered Intercellular Communication | Poor sleep is prevalent in patients with systemic inflammatory disorders, including rheumatoid arthritis, and, in addition to fatigue, pain, depression and inflammation, is associated with an increased risk of co-morbidity and all-cause mortality. | 24559487 |
| Inflammation, Cardiovascular Diseases, Cyclophosphamide/Vincristine/Dacarbazine Regimen, Obesity, physiopathological | Altered Intercellular Communication | Inflammation, insulin resistance and vascular dysfunction characterize obesity and predict development of cardiovascular disease (CVD). | 24559846 |
| Inflammation | Altered Intercellular Communication | Progerin was found to be significantly increased in the media of the dilated wall in tricuspidy, also showing increased periaortic inflammation. | 24560417 |
| Orbital Pseudotumor | Altered Intercellular Communication | This study was designed to compare GPA with other causes of orbital inflammation and to identify the presenting clinical and imaging features most likely to predict GPA and its systemic spread. | 24560566 |
| Orbital Pseudotumor | Altered Intercellular Communication | A total of 247 patients who had undergone orbital biopsies for clinical presentations with orbital inflammation were identified from the Institute of Ophthalmology pathology database. | 24560566 |
| Inflammation, Thrombophilia | Altered Intercellular Communication | These findings not only support the hypothesis of an association between inflammation and hypercoagulability, but more importantly, highlight the role of neutrophils in this process. | 24560897 |
| Inflammation, Pancreatitis | Altered Intercellular Communication | Chronic pancreatitis is a gradual, long-term inflammation of the pancreas that results in alteration of its normal structure and function. | 24560933 |
| Inflammation, Pathology | Altered Intercellular Communication | An increase in plasma kynurenic acid (KYNA) concentration has been observed following surgery, inflammation, and cerebral pathologies. | 24561546 |
| Inflammation, Electrocardiogram: myocardial infarction (finding) | Altered Intercellular Communication | Imaging myocardium at risk and coronary inflammation in non-ST-segment elevation myocardial infarction: combined use of FDG PET and optical coherence tomography. | 24561688 |
| Inflammation | Altered Intercellular Communication | In this report (figure), we describe the potential utility of FDG PET in defining the myocardium at risk and to unravel coronary inflammation in one NSTEMI patient with normal level of C-reactive protein. | 24561688 |
| Pancreatitis | Altered Intercellular Communication | Abdominal computed tomography revealed pancreatic and peripancreatic inflammation. | 24561842 |
| Arthritis, Disease remission | Altered Intercellular Communication | Diminution of miR-146a expression was observed in particular in patients with active disease, and correlated with joint inflammation. | 24562503 |
| Inflammation | Altered Intercellular Communication | Repeated strenuous work in the heat may predispose firefighters to augmented immune responses and inflammation. | 24563092 |
| Venous Thrombosis | Altered Intercellular Communication | Oral hormonal contraceptives may increase the risk of vascular events, even in people without personal or family history of venous thrombosis. | 24564051 |
| Inflammation, Diabetic Angiopathies, Diabetes Mellitus, Non-Insulin-Dependent | Altered Intercellular Communication | Monitoring of glycation, oxidative stress and inflammation in relation to the occurrence of vascular complications in patients with type 2 diabetes mellitus. | 24564602 |
| ARCN1 gene, Inflammation, Pulmonary Emphysema | Altered Intercellular Communication | In COPD with emphysema, loss of lung tissue may counterbalance the expected increase in density due to inflammation. | 24564813 |
| Inflammation, Adenolymphoma | Altered Intercellular Communication | We previously reported a case of immunoglobulin (Ig)G4-related immune inflammation in Warthin tumor. | 24565204 |
| Inflammation, Colorectal Carcinoma | Altered Intercellular Communication | Chronic inflammation plays a role in the development of colorectal cancer (CRC). | 24565956 |
| Gastrointestinal inflammation | Altered Intercellular Communication | Faecal calprotectin (FC) is a non-invasive marker of gastrointestinal inflammation. | 24566170 |
| Degenerative polyarthritis, Degenerative disorder | Altered Intercellular Communication | Osteoarthritis (OA) is a chronic degenerative joint disorder in which genetic, hormonal, mechanical and ageing factors affect its progression. | 24566851 |
| Inflammation, Data types - Address | Altered Intercellular Communication | The data identify a specific AGE (MG) as a modifiable risk factor for AD and MS, possibly acting via suppressed SIRT1 and other host defenses, to promote chronic oxidant stress and inflammation. | 24567379 |
| Inflammation, Fibrosis Assessment | Altered Intercellular Communication | Histologically, the excised tissue demonstrated marked inflammation with fibrosis surrounded by mononuclear epithelial cells. | 24568363 |
| Inflammation, Lacrimal sac, Orbital Neoplasms | Altered Intercellular Communication | It is likely that IgG4-related inflammation occurs in a lacrimal sac diverticulum, which should be considered a differential diagnosis in inferior orbital tumors. | 24568363 |
| Stomach Carcinoma | Altered Intercellular Communication | Neutrophil count and the inflammation-based glasgow prognostic score predict survival in patients with advanced gastric cancer receiving first-line chemotherapy. | 24568523 |
| Malignant Neoplasms, septic | Altered Intercellular Communication | Malignancy, hormonal and septic workup were all unremarkable. | 24569260 |
| Inflammation, Chronic Obstructive Airway Disease | Altered Intercellular Communication | Time course of inflammation resolution in patients with frequent exacerbations of chronic obstructive pulmonary disease. | 24569299 |
| Inflammation, Chronic Obstructive Airway Disease | Altered Intercellular Communication | When exacerbation of chronic obstructive pulmonary disease (AECOPD) occurs frequently, patients have high levels of airway and systemic inflammation and a poor quality of life. | 24569299 |
| Airway structure, Exacerbation | Altered Intercellular Communication | This study compared the nature and course of systemic and airway inflammation during AECOPD between patients who experienced frequent exacerbations and those with non-frequent exacerbations. | 24569299 |
| Refractory anemias, Inflammation | Altered Intercellular Communication | Women with anti-CCP-positive RA and anti-CCP-negative RA had different characteristics with regard to HLA shared epitope, cigarette smoking, and inflammation (cytokines). | 24569640 |
| Inflammatory Bowel Diseases, Inflammation, Primary malignant neoplasm, Specimen Type - Fistula | Altered Intercellular Communication | Our limited retrospective study demonstrates that rectal cancer in IBD patients can present as a circumferential wall thickening resembling inflammation and can occur in the absence of fistula or abscess. | 24570133 |
| Inflammation, Atrial Fibrillation by ECG Finding | Altered Intercellular Communication | Low-dose continuous infusion of landiolol reduced the incidence of postoperative atrial fibrillation, and significantly suppressed inflammation. | 24570490 |
| Inflammation, Impaired cognition | Altered Intercellular Communication | Systemic inflammation has been implicated in the development of cognitive dysfunction following carotid endarterectomy (CEA). | 24571940 |
| Inflammation, Hypercholesterolemia, Family history, Atherosclerosis | Altered Intercellular Communication | A correlation has been clearly shown between inflammation markers and subclinical atherosclerosis markers in the early stages of atherogenesis in subjects with familial hypercholesterolemia (FH). | 24572981 |
| Inflammation, Family history, Atherosclerosis | Altered Intercellular Communication | The aim of this study was to investigate potential inflammation markers in the diagnosis of atherosclerosis in children with FH. | 24572981 |
| TNF protein, human, Inflammation | Altered Intercellular Communication | Inflammation and macrophage activation markers (hsCRP, myeloperoxidase, chitotriosidase, YKL-40, TNF-a, IL-6, IL-18, MMP-1 and MMP-9) and lipid parameters of all patients were measured. | 24572981 |
| Inflammation, Atherosclerosis | Altered Intercellular Communication | ChT and YKL-40 seem to be the more predictable markers of atherosclerosis even in early ages (<6 years old) than other classical inflammation markers such as hs-CRP, IL-6 and TNF-a. | 24572981 |
| Inflammation, Fever, CTCAE | Altered Intercellular Communication | However, it was safe and well tolerated and reduced fever duration, some markers of inflammation, left anterior descending coronary artery Z score, and intravenous immunoglobulin reaction rates. | 24572997 |
| Inflammation | Altered Intercellular Communication | US assessment of synovial pathologic features in joints with mild inflammation was less reproducible than that in joints with severe inflammation. | 24574211 |
| Inflammation | Altered Intercellular Communication | Assessment of synovial fluid accumulation was not reproducible (ICCs 0.20-0.42) and did not substantially influence the global assessment of synovial inflammation (b = 0.06). | 24574211 |
| Inflammation, Spondylarthritis | Altered Intercellular Communication | Spinal inflammation in the absence of sacroiliac joint inflammation on magnetic resonance imaging in patients with active nonradiographic axial spondyloarthritis. | 24574227 |
| Inflammation, Spondylarthritis | Altered Intercellular Communication | To evaluate the presence of spinal inflammation with and without sacroiliac (SI) joint inflammation on magnetic resonance imaging (MRI) in patients with active nonradiographic axial spondyloarthritis (SpA), and to compare the disease characteristics of these subgroups. | 24574227 |
| Inflammation | Altered Intercellular Communication | Positive evidence of inflammation on MRI was defined as a SPARCC score of >=2 for either the SI joints or the spine. | 24574227 |
| Inflammation | Altered Intercellular Communication | Assessment by experienced readers showed that spinal inflammation on MRI might be observed in half of patients with nonradiographic axial SpA without SI joint inflammation. | 24574227 |
| Inflammation, Squamous metaplasia | Altered Intercellular Communication | The most common morphological finding in the epithelium was squamous metaplasia with occasional intense inflammation visible in the underlying mucosa, including cicatrization. | 24574420 |
| Inflammation, Fibrosis Assessment | Altered Intercellular Communication | ARFI correlated with fibrosis stage and hyaluronic acid but not with inflammation. | 24574802 |
| Nonalcoholic Steatohepatitis, Inflammation, Fibrosis Assessment, Fatty degeneration, Balloon Dilatation | Altered Intercellular Communication | Liver biopsy revealed mild steatosis, moderate inflammation, ballooning degeneration, and portal fibrosis with bridging fibrosis; on the basis of these findings, the diagnosis of nonalcoholic steatohepatitis was made. | 24575585 |
| Inflammation, Hypertension, CTCAE, Chronic Kidney Diseases | Altered Intercellular Communication | A positive association between inflammation and chronic kidney disease (CKD) has been reported but the impact of hypertension on this relation remains unclear. | 24575880 |
| Inflammation, Hypertensive (finding), Damage | Altered Intercellular Communication | Our data suggest that inflammation is strongly and independently associated with renal damage in hypertensive patients. | 24575880 |
| Inflammation, Fibrosis Assessment, Fatty degeneration | Altered Intercellular Communication | Relative enhancement negatively correlated with the degree of lobular inflammation (r = -0.59, P < .0001), ballooning (r = -0.44, P < .0001), and fibrosis (r = -0.59, P <= .0001), but not with steatosis (r = -0.16, P = .15). | 24576046 |
| Inflammation, Nerve Degeneration | Altered Intercellular Communication | The increase in BDNF might reflect a compensatory mechanism against early neurodegeneration and seems to be related to inflammation. | 24576746 |
| Inflammation, Systemic Inflammatory Response Syndrome | Altered Intercellular Communication | Debate remains regarding whether the systemic inflammatory response syndrome (SIRS) identifies patients with clinically important inflammation. | 24576975 |
| Pleurisy, Abnormality of the diaphragm | Altered Intercellular Communication | Endoscopic findings included diffuse parietal pleural inflammation in 26 patients (51%), parietal pleural studding in 19 patients (37.3%), a normal examination in three patients (5.9%), diffuse parietal pleural thickening in two patients (3.9%), and a diaphragmatic defect in one patient (2%). | 24577099 |
| Behavioral and psychological symptoms of dementia, Inflammation, "Alzheimers Disease | Altered Intercellular Communication | The impact of APOE status on relationship of biomarkers of vascular risk and systemic inflammation to neuropsychiatric symptoms in Alzheimer's disease. | 24577461 |
| Inflammation, Nail-Patella Syndrome, Data types - Address | Altered Intercellular Communication | Previous work has shown a relationship between serum biomarkers of vascular risk and inflammation and NPS in AD. | 24577461 |
| Inflammation, Data types - Address | Altered Intercellular Communication | Serum-based clinical biomarkers of vascular risk and biomarkers of inflammation related to AD were analyzed. | 24577461 |
| Stable chronic Graft vs Host Disease, Inflammation | Altered Intercellular Communication | Activation and migration of regulatory T cells (Treg) into tissue is critical in control of inflammation, but has not been examined extensively in chronic graft versus host disease (cGVHD). | 24577531 |
| Inflammation, Primary malignant neoplasm, Weight decreased | Altered Intercellular Communication | In male patients with cancer, low testosterone levels were associated with systemic inflammation, weight loss, increased symptom burden, and decreased survival. | 24577665 |
| Hepatitis | Altered Intercellular Communication | The result indicates that cellular immunology is involved in the pathogenesis of the liver inflammation process of FHB. | 24579463 |
| Inflammation | Altered Intercellular Communication | [Comparative study on the clinical characteristics of HBV infection patients with different pathologic inflammation grade]. | 24579472 |
| Inflammation, Liver damage | Altered Intercellular Communication | The serum AST, TBil, ALB and PTA were different and can partly reflect the inflammation degree of liver damage in patients with HBV infection. | 24579472 |
| Inflammation | Altered Intercellular Communication | HBV DNA level and HBeAg status can not indicate the inflammation degree in HBV infection patients. | 24579472 |
| Inflammation, Cervix carcinoma, Condylomata Acuminata, Cervical Intraepithelial Neoplasia | Altered Intercellular Communication | Among 3197 cases, 58.6% cases with chronic inflammation, 26.1% cases with condyloma or CIN I, 14.1% cases with CIN II-III, and 1.2% cases with invasive cervical carcinoma. | 24579473 |
| Diabetic Nephropathy, Inflammation, Kidney Diseases, Chronic Kidney Diseases | Altered Intercellular Communication | Determination of oxidative stress and cellular inflammation in patients with diabetic nephropathy and non-diabetic nephropathy being administered hemodialysis treatment due to chronic renal failure. | 24579657 |
| ARCN1 gene, Inflammation | Altered Intercellular Communication | In COPD smokers a weak correlation between 2006/2007 sputum markers of neutrophilic inflammation and the 5 year change in FEV1/FVC was found. | 24581181 |
| Inflammation, Diabetes Mellitus | Altered Intercellular Communication | The diabetes mellitus can affect various functions of the immune system of the individual, predisposing them to chronic inflammation, progressive degradation of tissues and decreased tissue repair. | 24581189 |
| Respiration Disorders, Bronchial Hyperreactivity | Altered Intercellular Communication | Asthma is a chronic respiratory disease characterized by hyper-responsiveness and bronchial inflammation. | 24581194 |
| Bronchitis | Altered Intercellular Communication | The bronchial inflammation in these patients can be monitored by measuring the fractional exhaled nitric oxide. | 24581194 |
| Inflammation, Neoplasms | Altered Intercellular Communication | Recent evidence indicates that tumor progression involves factors of systemic inflammation, such as platelets and lymphocytes. | 24581872 |
| Traditional Serrated Adenoma, Tubulovillous adenoma, Inflammation, Neoplasms, Tubular adenoma, Adenocarcinoma, Hyperplastic Polyp | Altered Intercellular Communication | Two hundred and fifty-eight biopsies revealed tubular adenomas (n = 91, one with intra-mucosal cancer), tubulovillous adenomas (n = 28), adenocarcinoma (n = 37), inflammation (n = 22), hyperplastic polyps (n = 54), serrated adenoma (n = 5), metastatic disease (n = 5), normal/benign mucosa or submucosal benign tumors (n = 13) or miscellaneous (n = 3). | 24581969 |
| Airway structure, Asthma | Altered Intercellular Communication | Airway inflammation is associated with asthma exacerbation risk, treatment response, and disease mechanisms. | 24582314 |
| Non-alcoholic Fatty Liver Disease, Inflammation, Obesity, Abdominal, Fatty degeneration | Altered Intercellular Communication | Nonalcoholic fatty liver disease (NAFLD), characterized by accumulation of hepatic triglycerides (steatosis), is associated with abdominal obesity, insulin resistance, and inflammation. | 24582567 |
| Inflammation | Altered Intercellular Communication | It was also significantly associated with severe intraplaque hemorrhage (P<.0001) and the prevalence of cap inflammation with macrophage (P=.03) and lymphocyte (P=.01) infiltration. | 24582790 |
| Diplopia, Inflammation, Eye Movements | Altered Intercellular Communication | Secondary outcome measures were changes in other parameters indicating the activity of TED, including soft tissue inflammation, diplopia, ocular motility restriction, and appearance. | 24582992 |
| Inflammatory abnormality of the eye | Altered Intercellular Communication | Although both groups experienced a significant reduction in periocular inflammation, the radiotherapy-treated group demonstrated a significantly greater improvement in ocular motility. | 24582992 |
| agep, Inflammation, Fever, CTCAE | Altered Intercellular Communication | Although rare, physicians should be aware that the administration of DAP can cause AGEP, which may complicate the clinical course of patients with a high fever and inflammation. | 24583445 |
| Gastrointestinal inflammation | Altered Intercellular Communication | Colonic expression of the peptide transporter PEPT1 is downregulated during intestinal inflammation and is not required for NOD2-dependent immune activation. | 24583477 |
| Inflammation | Altered Intercellular Communication | PEPT1 expression was consistently reduced under condition of acute or chronic experimental inflammation. | 24583477 |
| Inflammatory Bowel Diseases, Inflammation | Altered Intercellular Communication | PEPT1 expression levels were also decreased in descending colon of patients with IBD during acute inflammation, but the rs2297322 single-nucleotide polymorphism was not associated with IBD susceptibility in the German cohort. | 24583477 |
| Inflammatory Bowel Diseases, Gastrointestinal inflammation | Altered Intercellular Communication | PEPT1 expression is reduced during intestinal inflammation and PEPT1 is neither required for MDP-induced immune response nor is the PEPT1 rs2297322 single-nucleotide polymorphism associated with IBD susceptibility in our German cohort. | 24583477 |
| Communicable Diseases, Inflammation, Malignant Neoplasms | Altered Intercellular Communication | To differentially diagnose collagen disease, infection, malignancy, and inflammation of uncommon causes, we conducted brain and meningeal biopsies on the 15th hospital day. | 24583589 |
| Inflammation, Necrosis | Altered Intercellular Communication | Histopathological examination of the brain tissue showed mainly necrosis and inflammation. | 24583589 |
| Inflammation, Acute-On-Chronic Liver Failure, Bacterial Infections, CRNKL1 wt Allele, Liver Cirrhosis | Altered Intercellular Communication | According to the Acute-on-Chronic Liver Failure in Cirrhosis study, ACLF is now considered a new clinical entity because it is distinct from traditional decompensated cirrhosis, based not only on the presence of organ failure(s) and high mortality rate but also on younger age, alcoholic etiology of cirrhosis, higher prevalence of some precipitating events (bacterial infections, active alcoholism), and higher level of systemic inflammation. | 24583872 |
| Inflammation, Nasal Polyps, Chronic sinusitis | Altered Intercellular Communication | Eosinophilic inflammation of chronic rhinosinusitis with nasal polyps is related to OX40 ligand expression. | 24583911 |
| Inflammation, Nasal Polyps | Altered Intercellular Communication | In conclusion, the thymic stromal lymphopoietin/OX40 ligand axis is up-regulated in nasal polyposis and is related to the intensity of eosinophilic inflammation. | 24583911 |
| Tuberculosis, Pulmonary | Altered Intercellular Communication | Despite increased pro-inflammation compared to the uninfected controls; there was no up-regulation of IFN-g or the T cell chemoattractant CCL5 in the lung of patients with pulmonary TB. | 24584041 |
| Inflammation, Recurrent sinopulmonary infections | Altered Intercellular Communication | It is hypothesized that BRVO occurred secondary to raised fibrinogen levels, a common feature in CF resulting from chronic pulmonary infection and inflammation. | 24584306 |
| Inflammation, Elastosis perforans serpiginosa, Anorexia | Altered Intercellular Communication | Anthropometrics reveal depleted fat and lean body mass in EPS patients, which might be a result of anorexia and inflammation, and the reason that albumin was not an accurate marker of nutrition. | 24584612 |
| Inflammation, Peritonitis, Elastosis perforans serpiginosa | Altered Intercellular Communication | We observed no differences in baseline data between the groups, but the group with EPS had been on PD longer (84 +- 53 months vs 39 +- 20 months, p = 0.002) and had a higher cumulative number of days of peritoneal inflammation from peritonitis (17.2 +- 11.1 days vs 9.8 +- 7.9 days, p = 0.015). | 24584614 |
| Infarction, Inflammation, Malignant Neoplasms, Necrosis | Altered Intercellular Communication | The cytopathologic features of infarction are necrosis and worrisome nuclear features, which are often misinterpreted as either inflammation or malignancy. | 24585349 |
| Inflammation | Altered Intercellular Communication | Increased serum globulin, a positive phase reactant of inflammation, was found significant independent risk factor for development of serous DME. | 24585366 |
| Inflammation, Cardiovascular Diseases, Dyslipidemias, Depressed mood, Disease | Altered Intercellular Communication | We conclude that this study contributes the first evidence of a correlation between marked dyslipidemia and worsened Cu/Zn ratios in HPs, implying an increased risk of diseases associated with elevated oxidative stress, inflammation, and depressed immune function, such as cardiovascular diseases. | 24585396 |
| Inflammation, Leucocytic infiltrate, Squamous cell carcinoma of the head and neck | Altered Intercellular Communication | Monocyte chemotactic protein-1 (MCP-1) recruits monocytes and macrophages to inflammation sites, and inflammatory infiltration correlates with the progression of head and neck squamous cell carcinoma (HNSCC). | 24586454 |
| Communicable Diseases, Inflammation, Cerebrovascular accident | Altered Intercellular Communication | Inflammation and infection have been noted to increase stroke risk. | 24586739 |
| Inflammation, Dyslipidemias, HIV Infections, Atherosclerosis | Altered Intercellular Communication | The increased immune activation and inflammation of chronic HIV-infection and the characteristic dyslipidemias associated with HIV infection and antiretroviral therapy (ART) contribute to an increased risk of atherosclerotic vascular disease among HIV-infected adults. | 24586854 |
| Inflammation, Sleep Apnea, Obstructive, GDC Comorbidity Terminology, Osage language | Altered Intercellular Communication | Obstructive sleep apnea (OSA) is associated with systemic inflammation and induces various comorbid medical diseases. | 24586942 |
| Inflammation | Altered Intercellular Communication | Inflammation and adverse remodeling of the extracellular matrix may be involved in the pathogenesis. | 24586994 |
| Prostate, Carcinogenesis, Acute and chronic inflammation | Altered Intercellular Communication | Recent reports on Propionibacterium acnes (P. acnes) suggest that this bacterium is prevalent in the prostate, is associated with acute and chronic prostatic inflammation, and might have a role in prostate carcinogenesis. | 24587325 |
| Inflammation | Altered Intercellular Communication | The number of stromal macrophages with the bacterium correlated with the grade of chronic inflammation in both the PZ and TZ areas and with the grade of acute inflammation in the TZ area. | 24587325 |
| intraepithelial, Inflammation, Prostate, Prostate carcinoma | Altered Intercellular Communication | Immunohistochemical analysis with a novel monoclonal antibody for detecting P. acnes in the prostate suggested that intraepithelial P. acnes infection in non-cancerous prostate glands and inflammation caused by the bacterium may contribute to the development of prostate cancer. | 24587325 |
| Mental impairment, Neurotransmitters, Movement Disorders | Altered Intercellular Communication | This important and treatable neurotransmitter disorder must be considered in patients with a complex movement disorder with diurnal fluctuations with or without intellectual impairment. | 24588500 |
| Inflammation, Dental Plaque | Altered Intercellular Communication | Mediators of inflammation may control LOX expression in plaques and hence plaque stability. | 24588843 |
| Dyslexia, Asymmetry | Altered Intercellular Communication | PCDH11X, expressed in brain is implicated in cell-cell communication, verbal ability, cerebral asymmetry, and dendritic synaptic plasticity, may be regarded as a new candidate gene for dyslexia. | 24591081 |
| Granulomatous inflammation, AAVS1 gene, Vasculitis, CTCAE | Altered Intercellular Communication | Previous studies have reported that circulating HMGB-1 levels in patients with active antineutrophil cytoplasmic autoantibody (ANCA)-associated vasculitis (AAV) were associated with renal manifestations and burdens of granulomatous inflammation. | 24591411 |
| Tissue damage | Altered Intercellular Communication | High mobility group box 1 (HMGB-1), a kind of proinflammatory mediator, is associated with inflammatory conditions and tissue damage. | 24591411 |
| Degenerative polyarthritis, Inflammation, Obesity | Altered Intercellular Communication | Obesity is a major risk factor for the development of osteoarthritis (OA) that is associated with a state of low-grade inflammation and increased circulating levels of adipokines and free fatty acids (FFAs). | 24591481 |
| Inflammation, Periodontitis, Attachment (action), Periodontal Diseases | Altered Intercellular Communication | Chronic periodontitis (CP) is a multifactorial complex periodontal disease involving immune response, inflammation, alveolar bone resorption, and attachment loss. | 24592910 |
| Inflammatory Bowel Diseases, Inflammation, Sacroiliitis, Intestinal Diseases | Altered Intercellular Communication | Other factors such as type of IBD, disease duration and localisation of IBD, surgery history, biological inflammation, bowel disease activity and treatment were not associated with sacroiliitis. | 24593050 |
| Inflammation, Cyclophosphamide/Vincristine/Dacarbazine Regimen, Cardiovascular Diseases | Altered Intercellular Communication | Although data suggest that the ratio of leptin/adiponectin correlates with insulin resistance and predicts cardiovascular disease (CVD), there is scanty data on the relationship between the retinol-binding protein-4 (RBP4)/adiponectin ratio with insulin resistance and inflammation. | 24593134 |
| Abnormal renal function, Fever | Altered Intercellular Communication | Colchicine resulted in not only an amelioration of the acute febrile attacks of FMF inflammation, but also an improvement in kidney dysfunction due to AA amyloidosis. | 24593212 |
| Inflammation | Altered Intercellular Communication | Moreover, inflammation of the vascular walls and an aneurism in the right subclavian artery were observed on MRI. | 24593213 |
| Inflammation, Spanish Language | Altered Intercellular Communication | We recommended that it is important to evaluate the aortic involvement in late-onset SpA patients, when elevated systemic inflammation is observed. | 24593213 |
| Fibrosis Assessment, Myocarditis | Altered Intercellular Communication | Subclinical myocardial inflammation and diffuse fibrosis are common in systemic sclerosis--a clinical study using myocardial T1-mapping and extracellular volume quantification. | 24593856 |
| Fibrosis Assessment, Myocarditis | Altered Intercellular Communication | Diffuse myocardial fibrosis can be detected non-invasively by T1 and extracellular volume (ECV) quantification, while focal myocardial inflammation and fibrosis may be detected by T2-weighted and late gadolinium enhancement (LGE), respectively, using cardiovascular magnetic resonance (CMR). | 24593856 |
| Sample Size Calculation, Fibrosis Assessment, Inflammation | Altered Intercellular Communication | SSc patients had significantly higher native myocardial T1 values (1007 +- 29 vs. 958 +- 20 ms, p < 0.001), larger areas of myocardial involvement by native T1 >990 ms (median 52 vs. 3% in controls) and expansion of ECV (35.4 +- 4.8 vs. 27.6 +- 2.5%, p < 0.001), likely representing a combination of low-grade inflammation and diffuse myocardial fibrosis. | 24593856 |
| Sample Size Calculation, Myocarditis | Altered Intercellular Communication | Cardiac involvement is common in SSc even in the absence of cardiac symptoms, and includes chronic myocardial inflammation as well as focal and diffuse myocardial fibrosis. | 24593856 |
| Communicable Diseases, Pancreatic stone, Inflammation | Altered Intercellular Communication | Pancreatic stone protein (PSP)/regenerating protein 1-alpha (reg) is associated with inflammation, infection, and other disease-related stimuli. | 24594294 |
| Inflammation, Dental Plaque, Atherosclerosis | Altered Intercellular Communication | Imaging of the vulnerable carotid plaque: biological targeting of inflammation in atherosclerosis using iron oxide particles and MRI. | 24594295 |
| Inflammation, Dental Plaque, Atherosclerotic lesion | Altered Intercellular Communication | Inflammation is a key process in plaque destabilization and the propensity of atherosclerotic lesions to cause clinical sequelae. | 24594295 |
| Inflammation | Altered Intercellular Communication | There is currently no clinical imaging technique available to assess the degree of inflammation associated with plaques. | 24594295 |
| Inflammation, atherosclerotic | Altered Intercellular Communication | Inflammation associated with human ex vivo atherosclerotic plaques could be imaged using dual antibody-conjugated SPIO by MRI. | 24594295 |
| Inflammation, Dental Plaque | Altered Intercellular Communication | The asymptomatic plaque population exhibited heterogeneity in terms of inflammation. | 24594295 |
| Myositis, CTCAE 5.0, Myositis | Altered Intercellular Communication | Sporadic inclusion body myositis (sIBM), the most frequent myositis in elderly patients, is characterized by the presence muscle inflammation and degeneration. | 24594700 |
| Pneumonitis | Altered Intercellular Communication | Moreover, the presence of either bilateral lung inflammation or pulmonary consolidation on chest imaging on admission was related with fatal outcome (OR = 7.00; 95%CI, 1.10-44.61). | 24595034 |
| Autoimmune Diseases, Inflammation, Malignant Neoplasms | Altered Intercellular Communication | IL-17A has been shown to be a key mediator of inflammation in autoimmune diseases, transplant rejection and cancers. | 24595078 |
| Inflammation, Postoperative Period | Altered Intercellular Communication | This paradox may indicate that the contribution of inflammation to postoperative sequalae is less than commonly thought or that systemic doses are too low in their local concentration. | 24595228 |
| Inflammation, Erythema | Altered Intercellular Communication | Local skin reactions, consisting of mild to moderate erythema and flaking/scaling, were significantly improved by 1 week after peak inflammation and were not treated in most patients. | 24595570 |
| Inflammation | Altered Intercellular Communication | Magnetic resonance imaging (MRI) of the optic nerve revealed an inflammation of the left optic nerve with chiasmatic involvement, without any encephalic or medullar lesion. | 24596142 |
| Orbital Pseudotumor | Altered Intercellular Communication | Resolution of idiopathic granulomatous orbital inflammation with intraorbital triamcinolone. | 24596409 |
| Orbital Pseudotumor | Altered Intercellular Communication | Biopsy and histopathology of the lesion identified idiopathic granulomatous orbital inflammation. | 24596409 |
| Necrotizing granulomatous inflammation | Altered Intercellular Communication | Such treatment may thus form an alternative to oral corticosteroid therapy in the management of granulomatous orbital inflammation. | 24596409 |
| Inflammation, Swelling | Altered Intercellular Communication | Initially, the inflammation was controlled successfully with corticosteroids but the swelling persists to this day. | 24597112 |
| Calcinosis, Aortic Valve Stenosis | Altered Intercellular Communication | Taken together, these results indicate that inflammatory signaling through LTB4 may be more closely linked to calcification and aortic stenosis than signaling through TGF-beta1 and MPs. | 24597398 |
| Neurogenic Inflammation, Hypersensitivity, Edema | Altered Intercellular Communication | Neurogenic inflammation involves vasodilation, oedema and sensory nerve hypersensitivity. | 24597665 |
| Malignant mesothelioma, Carcinogenesis, Inflammation | Altered Intercellular Communication | Asbestos causes lung cancer and malignant mesothelioma, and chronic inflammation is considered to participate in carcinogenesis. | 24598051 |
| Carcinogenesis | Altered Intercellular Communication | Reactive oxygen/nitrogen species are generated in biological systems under inflammatory conditions and may contribute to carcinogenesis by causing DNA damage. | 24598051 |
| Inflammation, Squamous cell carcinoma, Smoking, Adenocarcinoma, Small cell carcinoma of lung | Altered Intercellular Communication | We analyzed the presence of distinct inflammatory cells and the macrophage activation phenotype together with the levels of vascular endothelial growth factor (VEGF) and interleukin 8 (IL-8) within BALF from 54 smoking lung cancer patients including 36 squamous cell carcinoma (SCC), 9 adenocarcinoma (AC), and 9 small cell lung cancer (SCLC) in comparison with those from 13 non-smoking and 7 smoking patients with nonspecific chronic inflammation and 8 non-smoking normal controls. | 24598169 |
| Inflammation, Carcinoma of lung | Altered Intercellular Communication | We found a significantly lower percentage of total macrophages and a much higher percentage of neutrophils among all inflammatory cells in BALF from lung cancer and non-specific chronic inflammation patients. | 24598169 |
| Inflammation | Altered Intercellular Communication | Our results suggest that the detection of infiltrating inflammatory cells and pro-angiogenic factors in BALF will be helpful for diagnosis of cancerous inflammation in lungs. | 24598169 |
| palladium, Inflammation, Tissue injury, Peritonitis | Altered Intercellular Communication | Taken together these data suggest that the TWEAK/Fn14 system may promote inflammation and tissue injury during peritonitis and PD. | 24599047 |
| Inflammation, Demographics Domain, Diabetes Mellitus, Coronary Artery Disease | Altered Intercellular Communication | Both coronary artery disease (CAD) and diabetes mellitus (DM) are associated with inflammation. | 24599246 |
| Malignant Neoplasms | Altered Intercellular Communication | The COX2 rs5277 (306G>C) polymorphism has been associated with inflammation-associated cancers. | 24599585 |
| Vasculitis, CTCAE | Altered Intercellular Communication | These results suggest that, upon inflammatory conditions in GPA, renal MECs may contribute to the recruitment and activation of NK cells in the target vessel wall, which may participate in the necrotizing vasculitis of the kidney during this disease. | 24600034 |
| Inflammation, Hyperkeratosis | Altered Intercellular Communication | The most common complications observed were chronic inflammation (54.2%) and hyperkeratosis (48.2%). | 24601858 |
| Chronic inflammation, Communicable Diseases, Chronic osteomyelitis, Cerebrovascular accident, cyclophosphamide/methotrexate/vincristine protocol | Altered Intercellular Communication | In this study, it was assessed whether chronic osteomyelitis (COM), an infectious disease with chronic inflammation, increases stroke risk. | 24602152 |
| Inflammation, Demyelination, Axonal loss, MS gene | Altered Intercellular Communication | Chronic demyelination, on-going inflammation, axonal loss and grey matter neuronal injury are likely pathological processes that contribute to disease progression in multiple sclerosis (MS). | 24602691 |
| Eosinophilic inflammation | Altered Intercellular Communication | The results obtained in this in vitro model suggest that FF may reduce upper airway eosinophilic inflammation through decreasing cytokine secretion from epithelial cells and reducing eosinophil survival. | 24603043 |
| Inflammation | Altered Intercellular Communication | If symptoms and inflammation persist and no narrowing is appreciated, an elemental diet can be considered; however, the long-term use of this in older children and adults may be difficult. | 24603397 |
| Inflammation, Chronic disease, Obesity, Weight Gain, Overweight | Altered Intercellular Communication | Inflammation may constitute an underlying mechanism for increased risk of developing chronic diseases in later years, but few prospective studies have assessed the influence of low-grade inflammation on body weight gain, particularly among children in low- to middle-income settings with lower prevalence of overweight and obesity. | 24603645 |
| Inflammation, Skin, Human | Altered Intercellular Communication | Characterisation of leukocytes in a human skin blister model of acute inflammation and resolution. | 24603711 |
| Inflammation | Altered Intercellular Communication | There is an increasing need to understand the leukocytes and soluble mediators that drive acute inflammation and bring about its resolution in humans. | 24603711 |
| Inflammation | Altered Intercellular Communication | Quantification of NETs in bronchial aspirates may provide a new indicator of inflammation. | 24603817 |
| Inflammation, Pathologic Neovascularization, Fibrosis Assessment, Cicatrization | Altered Intercellular Communication | Histopathology analysis revealed inflammation, scarring, neovascularisation and extensive leaflet fibrosis in diseased mitral valve. | 24603967 |
| Inflammation, Diabetic Retinopathy, GDC Disease Response Terminology | Altered Intercellular Communication | Inflammation may contribute to the pathogenesis of diabetic retinopathy (DR). | 24604308 |
| Inflammation | Altered Intercellular Communication | Vitamin D deficiency is associated with inflammation in older Irish adults. | 24606079 |
| Autoimmune Diseases, Inflammation | Altered Intercellular Communication | Inadequate vitamin D status is common within elderly populations and may be implicated in the etiology of autoimmune disease and inflammation. | 24606079 |
| Hyperlipidemia, Inflammation, Diabetes Mellitus, Non-Insulin-Dependent | Altered Intercellular Communication | Compared with lean control subjects, those with Type 2 diabetes had more deleterious profiles of hyperlipidaemia, vitamin D deficiency, inflammation and maximal oxygen uptake relative to body mass. | 24606573 |
| Airway structure, Asthma, IL13 gene | Altered Intercellular Communication | Ongoing allergic rhinitis impairs asthma control by enhancing the lower airway inflammation. | 24607045 |
| Airway structure, Asthma, IL13 gene, MS4A2 wt Allele | Altered Intercellular Communication | This observational study of patients with atopy indicates that the ongoing allergic rhinitis is related to worsening of asthma by enhancing the lower airway inflammation. | 24607045 |
| Inflammation | Altered Intercellular Communication | Chronic cadmium exposure may cause disease through induction of systemic oxidative stress and inflammation. | 24607659 |
| Inflammation, Chronic sinusitis, IL13 gene | Altered Intercellular Communication | Causes of use included acute inflammation (n=6), chronic rhinosinusitis (n=2), and allergic rhinitis (n=20) and unknown cause (n=5). | 24608651 |
| Inflammation | Altered Intercellular Communication | The patient exhibited an extreme increase in interleukin-17 (IL-17), one of the major regulatory cytokines for inflammation and neutrophil migration. | 24609719 |
| Pain Distress Question, Inflammation | Altered Intercellular Communication | Thus, we carried out a 1 week clinical trial to examine the extent to which UP446-a natural proprietary blend of S. baicalensis and A. catechu (UP446)-decreases knee joint pain, mobility, and biomarkers of inflammation in comparison to naproxen. | 24611484 |
| Inflammatory Bowel Diseases, Inflammation | Altered Intercellular Communication | TWT was correlated with macroscopic IBD scores and histological inflammation scores. | 24612000 |
| Inflammation, Ulcerative Colitis | Altered Intercellular Communication | There was a strong correlation of TWT with histological inflammation scores (UC: r = 0.43; CD: r = 0.69). | 24612000 |
| Ulcerative Colitis, Colitis | Altered Intercellular Communication | EUS can differentiate active UC from CD and quantify the level of colonic inflammation. | 24612000 |
| Periodontitis, atherosclerotic | Altered Intercellular Communication | Chronic periodontitis (CP) and atherosclerotic and aortic aneurysmal vascular diseases (VD) are inflammatory conditions that share a number of predisposing factors. | 24612355 |
| Inflammation, Dental Plaque, Atherosclerosis | Altered Intercellular Communication | Adhesion molecules CD146 and its soluble form strongly correlated with the development of inflammation of atherosclerosis and plaque instability. | 24612514 |
| Renal Insufficiency, Inflammation | Altered Intercellular Communication | These cases can present significant technical and management challenges secondary to the underlying pathology, associated anatomic inflammation, and impaired functional status. | 24612704 |
| Inflammation, Atrial Fibrillation by ECG Finding | Altered Intercellular Communication | Serum inflammation markers predicting successful initial catheter ablation for atrial fibrillation. | 24613042 |
| Idiopathic Interstitial Pneumonias, Fibrosis Assessment, Pneumonia, Interstitial, Interstitial inflammation | Altered Intercellular Communication | Idiopathic interstitial pneumonia (IIP) is characterized by chronic interstitial inflammation and fibrosis. | 24613046 |
| Arterial Stiffness, Inflammation, Diabetes Mellitus, Insulin-Dependent | Altered Intercellular Communication | No association of dietary fiber intake with inflammation or arterial stiffness in youth with type 1 diabetes. | 24613131 |
| Arterial Stiffness, Inflammation, Diabetes Mellitus, Insulin-Dependent, Choroidal and Ciliary Body Melanoma pT1d TNM Finding v8 | Altered Intercellular Communication | To examine the association of dietary fiber intake with inflammation and arterial stiffness among youth with type 1 diabetes (T1D) in the US. | 24613131 |
| Arterial Stiffness, Inflammation | Altered Intercellular Communication | In multivariable analyses, fiber intake was not associated with inflammation or arterial stiffness. | 24613131 |
| Inflammation, Vascular Stiffness, Choroidal and Ciliary Body Melanoma pT1d TNM Finding v8 | Altered Intercellular Communication | Among youth with T1D, fiber intake does not meet recommendations and is not associated with measures of systemic inflammation or vascular stiffness. | 24613131 |
| Inflammation, Aortic Aneurysm, Abdominal | Altered Intercellular Communication | Association between seven single nucleotide polymorphisms involved in inflammation and proteolysis and abdominal aortic aneurysm. | 24613192 |
| Communicable Diseases, Inflammation, Malignant Neoplasms | Altered Intercellular Communication | Patients with malignancy, pregnancy, concurrent inflammatory or infectious diseases, or concomitant use of any medication affecting inflammation status were excluded. | 24613294 |
| Inflammation, Impaired | Altered Intercellular Communication | The ability of HDL to attenuate endothelial inflammation is impaired in acute MI, and this metric of HDL function may serve as a predictor of new MACE, even independent of HDL cholesterol and apolipoprotein A-I. | 24613518 |
| Chronic inflammation of orbit, Inflammation | Altered Intercellular Communication | Biopsy-proven chronic orbital inflammation was present in all patients; this resembled reactive lymphoid hyperplasia (RLH) in 7 patients and immunoglobulin (Ig) G4-related sclerosing inflammation in 7 patients. | 24613826 |
| Tissue damage, Inflammation | Altered Intercellular Communication | Recovery after cardiac surgery is a complex process that has to compensate for both individual variability and extensive tissue damage in the context of systemic inflammation. | 24614541 |
| Inflammation | Altered Intercellular Communication | Protein glycosylation is essential in many steps of the inflammatory cascade, but due to technological limitations the role of individual variation in glycosylation in systemic inflammation has not been addressed until now. | 24614541 |
| Inflammation | Altered Intercellular Communication | Our results indicate that individual variation in IgG glycosylation changes during acute systemic inflammation associates with increased mortality risk and indicates new avenues for the development of personalized diagnostic and therapeutic approach. | 24614541 |
| Nasolacrimal Duct Obstruction, Inflammation, Lacrimal Duct Obstruction | Altered Intercellular Communication | Etiologies of lacrimal obstruction requiring a dacryocystorhinostomy (DCR) have been reviewed previously but most commonly are thought to result from "primary acquired" nasolacrimal duct obstruction, a process of chronic inflammation in a narrowed duct. | 24614546 |
| Inflammation, Fibrosis Assessment, Hepatitis, Chronic | Altered Intercellular Communication | The rate of clinical diagnosis matching the pathological diagnosis for fibrosis was higher than for inflammation (83.33 vs 54.76%), especially in moderate (83.33 vs 26.67%) and severe chronic hepatitis (66.67 vs 16.67%). | 24615102 |
| Inflammation, Fibrosis Assessment | Altered Intercellular Communication | In HBV carriers, the degree of inflammation and fibrosis in most cases was mild, and the younger the patients, the higher the ratios of G0 and S0. | 24615102 |
| Inflammation, Fibrosis Assessment, Hepatitis | Altered Intercellular Communication | The clinical diagnosis was correct in most cases, especially for inflammation and in mild chronic hepatitis; the patients who were diagnosed as HBV carriers actually already had inflammation and fibrosis. | 24615102 |
| Inflammation, Pulmonary granuloma, Fever, CTCAE, Cystitis | Altered Intercellular Communication | The most frequent complications of such treatment include fever and urinary bladder inflammation, while serious complications of haematogenous organ inflammation, especially inflammation of the lungs with the formation of pulmonary caseosus granulomas, are rarely seen. | 24615200 |
| Stomach Carcinoma | Altered Intercellular Communication | The most studied genetic susceptibility factors involved in gastric carcinoma (GC) risk are polymorphisms in the inflammation-linked genes interleukin 1 (IL1) B and IL1RN. | 24615437 |
| Inflammation, Metabolic Diseases | Altered Intercellular Communication | Serum plasmalogens (Pls) (1-O-alk-1'-enyl-2-acyl glycerophospholipids) are of particular interest for studies on metabolic disorders associated with oxidative stress and chronic inflammation. | 24616482 |
| Inflammation, Crohn Disease | Altered Intercellular Communication | The impact of inflammation on vitamin D and mineral metabolism has not been well-characterized in Crohn's disease (CD). | 24617709 |
| Inflammation, Primary malignant neoplasm | Altered Intercellular Communication | The interaction between inflammation and cancer is well established. | 24617829 |
| Inflammation | Altered Intercellular Communication | Surrogate markers of systemic inflammation, such as the neutrophil/lymphocyte ratio (NLR), may be associated with the long-term oncological outcome. | 24617829 |
| ARCN1 gene, Inflammation, Lung Injury, Exacerbation, Chronic Obstructive Airway Disease | Altered Intercellular Communication | Chronic obstructive pulmonary disease (COPD) exacerbations are accompanied with increased systemic inflammation, which accelerate the pulmonary function injury and impair the quality of life. | 24618290 |
| Inflammation, Exacerbation | Altered Intercellular Communication | The CAT is associate with the changes of systemic inflammation following COPD exacerbations. | 24618290 |
| Human papilloma virus infection, Immunocompromised Host | Altered Intercellular Communication | Rather in contemporary times, common risk factors include HPV infection, immunocompromised states, and chronic scrotal inflammatory conditions. | 24618607 |
| APP gene, Vasculitis, Aortic Aneurysm, Abdominal | Altered Intercellular Communication | Chronic vascular inflammation is a key hallmark in the pathogenesis of abdominal aortic aneurysm (AAA). | 24618883 |
| Inflammation, Diabetes Mellitus | Altered Intercellular Communication | Subclinical inflammation may be a mechanism linking air pollution with diabetes. | 24619127 |
| Inflammation, Neuronal loss in central nervous system, Cerebral atrophy | Altered Intercellular Communication | The successfully engrafted younger sibling had less brain inflammation, cortical atrophy, and neuronal loss on neuro-imaging and neuropathology compared to the untreated older sister. | 24619150 |
| White matter | Altered Intercellular Communication | Although HSCT did not halt the course of ACOX1 deficiency, it reduced the extent of white matter inflammation in the brain. | 24619150 |
| Pterygium Of Conjunctiva And Cornea, Conjunctivitis | Altered Intercellular Communication | Pterygium recurrence, ocular discomfort, persistent conjunctival inflammation, and graft complications were evaluated postoperatively. | 24619168 |
| Conjunctivitis | Altered Intercellular Communication | Persistent conjunctival inflammation was also significantly higher in the summer group than in the winter group (30.4% vs. 6.2%, P = 0.022). | 24619168 |
| Inflammation, Pterygium Of Conjunctiva And Cornea, Conjunctivitis | Altered Intercellular Communication | Pterygium recurrence was significantly higher in eyes with persistent conjunctival inflammation than in eyes without inflammation (66.6% vs. 4.3%, P < 0.001). | 24619168 |
| Granulomatous inflammation | Altered Intercellular Communication | Histological investigations showed an intense granulomatous inflammation with severe destruction of the parenchyma. | 24619528 |
| Inflammation, Ulcerative Colitis | Altered Intercellular Communication | Atypical distribution of inflammation in newly diagnosed ulcerative colitis is not rare. | 24619632 |
| Inflammation, Ulcerative Colitis | Altered Intercellular Communication | Appendiceal orifice inflammation (AOI) is a common 'skip lesion' in patients with ulcerative colitis (UC). | 24619632 |
| Inflammation | Altered Intercellular Communication | Prospective studies showed that chronic subclinical inflammation is a predictor of T2DM. | 24619654 |
| Inflammation, Cardiovascular Diseases | Altered Intercellular Communication | These data suggest that a value of a 1-h OGTT glucose >=155 mg/dl may be helpful to identify a subset of normal glucose tolerance individuals at risk for chronic subclinical inflammation, a predictor of T2DM, and cardiovascular diseases. | 24619654 |
| Inflammation, Paralysed, Herpes Simplex Infections, herpesvirus 3, human, Bell Palsy | Altered Intercellular Communication | The reactivation of latent herpes simplex virus (HSV) or varicella-zoster virus (VZV) with subsequent inflammation and entrapment of the facial nerve in the narrow labyrinthine segment has been implicated as a cause of facial paralysis, but the active role of these viruses in Bell's palsy is still discussed. | 24619963 |
| Communicable Diseases, Periodontitis, atherosclerotic | Altered Intercellular Communication | A persistent infection, such as chronic periodontitis, may influence changes in the systemic levels of HsCRP, LDL and HDL, which potentially have an impact on inflammation-associated atherosclerotic processes, such as CAD. | 24620793 |
| ARCN1 gene, Inflammation, Chronic Obstructive Airway Disease | Altered Intercellular Communication | Increased oxidative stress and inflammation has a role in the pathogenesis of chronic obstructive pulmonary disease (COPD). | 24621680 |
| Neurogenic Inflammation, Pain Disorder | Altered Intercellular Communication | The authors hypothesized that capsaicin-induced pain and neurogenic inflammation (skin perfusion and flare area) are increased in patients with complex regional pain syndrome compared with that in controls. | 24621686 |
| Pain Distress Question, Neurogenic Inflammation | Altered Intercellular Communication | The flare response to capsaicin was normal, suggesting that the increased pain response was not due to increased neurogenic inflammation. | 24621686 |
| Diabetes Mellitus, Non-Insulin-Dependent, Obesity, Cardiovascular Diseases | Altered Intercellular Communication | Genome-wide association studies (GWAS) have identified single-nucleotide polymorphisms (SNPs) associated with CRP concentrations and inflammation-related traits such as cardiovascular disease, type 2 diabetes mellitus, and obesity. | 24622110 |
| Inflammation, Heart failure | Altered Intercellular Communication | Soluble ST2 (sST2), a biomarker related to inflammation, is associated with outcomes of patients with heart failure. | 24622243 |
| Airway structure, ARCN1 gene, Asthma | Altered Intercellular Communication | However, airway inflammation is generally less responsive to steroids in COPD than in asthma. | 24622644 |
| Acute myocardial infarction, Upper Respiratory Infections | Altered Intercellular Communication | Three participants died: two before randomisation and one in the basal-bolus group (due to severe acute myocardial infarction and respiratory tract inflammation). | 24622667 |
| Plaque, Atherosclerotic | Altered Intercellular Communication | Imaging atherosclerotic plaque inflammation via folate receptor targeting using a novel 18F-folate radiotracer. | 24622812 |
| Inflammation, Rupture | Altered Intercellular Communication | In nascent lesions, they coordinate the scavenging of lipids and cellular debris to define the likelihood of plaque inflammation and eventually rupture. | 24622812 |
| Inflammation | Altered Intercellular Communication | Selectively targeting FR-b-positive macrophages through folate-based radiopharmaceuticals may be useful for noninvasive imaging of plaque inflammation. | 24622812 |
| Inflammation, Non-Small Cell Lung Carcinoma, Carcinoma of lung | Altered Intercellular Communication | Although the alterations of lipid profile in lung cancer have been documented, the prognostic value of serum HDL-C level and its correlation with inflammation in NSCLC remain unknown. | 24625581 |
| Autoimmune Diseases of the Nervous System | Altered Intercellular Communication | DARC shuttles inflammatory chemokines across the blood-brain barrier during autoimmune central nervous system inflammation. | 24625696 |
| Rheumatoid Arthritis, Tumor necrosis, Inflammation | Altered Intercellular Communication | In rheumatoid arthritis it is used because the cytokines that cause inflammation in this disease are regulated by tumor necrosis factor alpha and IL-1. | 24626663 |
| Inflammation, Osage language | Altered Intercellular Communication | The subgroup of patients with OSA and RFL have several factors that promote inflammation of the upper airway. | 24626885 |
| Inflammation, Acute heart failure | Altered Intercellular Communication | Previous studies have demonstrated the role of inflammation in acute heart failure. | 24626945 |
| Inflammation, Ischemic stroke | Altered Intercellular Communication | High-sensitivity C-reactive protein and interleukin-6-dominant inflammation and ischemic stroke risk: the northern Manhattan study. | 24627113 |
| Inflammation, Hyperuricemia, Hypertension, CTCAE, Metabolic Syndrome X | Altered Intercellular Communication | Interaction of inflammation, hyperuricemia, and the prevalence of hypertension among adults free of metabolic syndrome: NHANES 2009-2010. | 24627417 |
| Inflammation, Hypertension, CTCAE, Hyperuricemia | Altered Intercellular Communication | Hyperuricemia and markers of inflammation are correlated with the risk for hypertension. | 24627417 |
| Airway structure, Asthma | Altered Intercellular Communication | Th17-mediated neutrophilic airway inflammation has been implicated in decreased response to glucocorticoids in asthma. | 24627531 |
| Inflammation, Asthma | Altered Intercellular Communication | We show that glucocorticoids enhance CCL20 production by bronchial epithelium, which may constitute a novel mechanism in Th17-mediated glucocorticoid-insensitive inflammation in asthma. | 24627531 |
| Guinea (geographic area), Intraepithelial Neoplasia | Altered Intercellular Communication | Our results showed that 45 cases of intraepithelial neoplasia disappeared when chronic inflammation left, and 33 cases were given the original diagnoses and two cases developed into high-grade GIN. | 24627924 |
| Inflammation, Guinea (geographic area) | Altered Intercellular Communication | Results showed four cases of chronic inflammation, 11 cases with original diagnoses maintained, and three cases of high-grade GIN. | 24627924 |
| Intestinal metaplasia, Guinea (geographic area) | Altered Intercellular Communication | GIN occurred frequently in patients with more severe pathological inflammations under endoscope, which also had certain correlations with intestinal metaplasia. | 24627924 |
| Airway structure | Altered Intercellular Communication | Asian dust storms (ADS) contain various airborne particles that may augment airway inflammation by increasing the level of interleukin-8. | 24628524 |
| Airway structure | Altered Intercellular Communication | ADS airborne particles may increase airway inflammation through enhancement of interleukin-8 transcriptional activity. | 24628524 |
| vascular inflammations | Altered Intercellular Communication | Pentraxin 3 (PTX3) is probably a specific marker of vascular inflammation. | 24628740 |
| Inflammation, Atherosclerosis | Altered Intercellular Communication | These results support the hypothesis that PTX3 reflects different aspects of inflammation than CRP, and may provide additional insights into the development and progression of atherosclerosis. | 24628740 |
| Inflammation, Stomach Carcinoma, Infection caused by Helicobacter pylori | Altered Intercellular Communication | Helicobacter pylori infection is a strong risk factor for gastric cancer, likely due to the extensive inflammation in the stomach mucosa caused by these bacteria. | 24628819 |
| Inflammation, Atherosclerosis | Altered Intercellular Communication | Neutrophil (PMN) leukocytes participate to the initial phases of atherosclerosis through the release of Interleukin 8 (CxCL8; IL-8) that contribute to amplification of inflammation. | 24629144 |
| Type 1 Autoimmune Pancreatitis, Colitis | Altered Intercellular Communication | Inflammation of colon adenoma in the setting of type 1 autoimmune pancreatitis. | 24629174 |
| Inflammation, Fibrosis Assessment, Colonic adenomas, Waldenstrom Macroglobulinemia, Adenoma, Phlebitis | Altered Intercellular Communication | Both colon adenomas from patients with (IgG4 adenomas) and without (Non-IgG4 adenomas) IgG4-RD were characterized by moderate to severe lymphoplasmacytic and eosinophilic inflammation without fibrosis or phlebitis. | 24629174 |
| Inflammation, Fatty degeneration, Shwachman syndrome, Neoplasms | Altered Intercellular Communication | The tumor was intermingled with two pathological changes characteristic of Shwachman-Diamond syndrome: fatty degeneration of the pancreas and inflammation of the villous stroma of the duodenum. | 24629175 |
| Inflammation, Carcinogenesis | Altered Intercellular Communication | Considering that SBDS protein regulates mitosis and its suppression causes genomic instability, this case might provide an example of carcinogenesis based on genomic instability, together with degenerative changes and chronic inflammation, at a very young age. | 24629175 |
| Inflammation, ME1 gene, Depression, CTCAE | Altered Intercellular Communication | Clinical investigators are encouraged to assess markers of inflammation and review detailed information on risk factors such as waist circumference for MeS in patients with depression. | 24629898 |
| Iron deficiency, Inflammation, Normocytic anemia | Altered Intercellular Communication | RTD was associated with normocytic anemia, accompanying iron deficiency and inflammation. | 24630338 |
| Inflammation, Malignant Neoplasms | Altered Intercellular Communication | Neutrophil/lymphocyte ratio (NLR), a marker of host inflammation, is prognostic in several cancers but has not been reviewed in large BTC series, or advanced BTC (ABTC) at diagnosis. | 24630393 |
| Inflammation, Malignant Neoplasms | Altered Intercellular Communication | Pretreatment neutrophil-to-lymphocyte ratio (NLR) is a marker of systemic inflammation that has been associated with adverse survival in a variety of malignancies. | 24630414 |
| Seizures, Abscess, Cerebral dysfunction | Altered Intercellular Communication | Brain abscesses often cause symptoms of brain dysfunction, including seizures, suggesting interference with normal neurotransmission. | 24632003 |
| Inflammation, Fatigue | Altered Intercellular Communication | Fatigue has been associated with inflammation and cytokine activity among adults, but this relationship has not been evaluated among adults living with HIV. | 24632226 |
| Inflammation, Fatigue | Altered Intercellular Communication | This study strengthens the evidence for an association between inflammation and fatigue. | 24632226 |
| Pneumonitis | Altered Intercellular Communication | We hypothesize that selective pulmonary perfusion (sPP) of the lungs leads to a reduction of pulmonary inflammation and a better clinical outcome. | 24632426 |
| Inflammation, Myocardial Ischemia | Altered Intercellular Communication | Also, we tested whether normal food intake or inflammation influenced lipoprotein(a)'s ability to predict ischemic heart disease. | 24632508 |
| Inflammation, Electrocardiogram: myocardial infarction (finding), Myocardial Ischemia | Altered Intercellular Communication | The ability of elevated lipoprotein(a) levels to predict ischemic heart disease and myocardial infarction in the general population was not affected by normal food intake or inflammation. | 24632508 |
| Respiratory Distress Syndrome, Adult, Inflammation, Respiratory Distress Syndrome, Newborn | Altered Intercellular Communication | Pulmonary coagulopathy may play a pathogenetic role in acute respiratory distress syndrome (ARDS), by contributing to alveolocapillary inflammation and increased permeability. | 24632673 |
| Drug Eruptions, Inflammation, Gingival Overgrowth | Altered Intercellular Communication | Gingival overgrowth (GO) frequently occurs in transplant patients receiving immunosuppressive drugs such as cyclosporine and this gingival inflammation might play an important role in the pathogenesis of drug-induced GO. | 24632797 |
| Inflammation, Behavioral Symptoms, Breast Carcinoma | Altered Intercellular Communication | Elevated inflammation predicts behavioral symptoms, disease progression, and mortality in patients with breast cancer and breast cancer survivors, although predictors of inflammation remain largely unknown. | 24632893 |
| Inflammation, Primary malignant neoplasm | Altered Intercellular Communication | However, little research has examined the association between childhood adversity and inflammation in the context of cancer, where inflammation is particularly relevant for health. | 24632893 |
| Inflammation, Breast Carcinoma | Altered Intercellular Communication | Childhood adversity was associated with elevated markers of inflammation in breast cancer survivors, with potential negative implications for health and well-being. | 24632893 |
| Inflammation | Altered Intercellular Communication | Pentraxin 3 (PTX3) is an inflammatory protein produced at inflammation sites such as leukocytes and vascular endothelial cells. | 24632958 |
| Squamous cell carcinoma, Malignant Neoplasms, Childhood Angiosarcoma | Altered Intercellular Communication | Morphologically, PH may be confused with other lesions, from benign vasoformative neoplasms and reactive inflammatory conditions to malignancies such as angiosarcoma or squamous cell carcinoma. | 24632981 |
| Inflammation, Pain Distress Question, Gout | Altered Intercellular Communication | The administration of systemic corticosteroids relieved the joint inflammation and pain; however, the urate level increased to 28 mg/dL and the gout attacks recurred. | 24633032 |
| Diverticulosis of the duodenum, Inflammation, Neoplasm Metastasis | Altered Intercellular Communication | Chronic inflammation predisposing to cancer metastasis: lesson learned from a chronically embedded foreign body in a duodenal diverticulum. | 24633596 |
| Inflammation, Chordoid meningioma, Chronic fatigue | Altered Intercellular Communication | Chordoid meningioma in an adult patient presenting with chronic fatigue and systemic inflammation. | 24635333 |
| Inflammation, Anemia, Neoplasms | Altered Intercellular Communication | Aspecific neurologic symptoms and biochemical indices of inflammation and anaemia triggered an MRI, revealing a tumor with compression of the medulla oblongata. | 24635333 |
| Inflammation, Weight decreased | Altered Intercellular Communication | Aerobic exercise and weight loss reduce vascular markers of inflammation and improve insulin sensitivity in obese women. | 24635342 |
| vascular inflammations, Obesity | Altered Intercellular Communication | Obesity and insulin resistance worsen markers of systemic and vascular inflammation. | 24635342 |
| Inflammation, Neurologic Symptoms | Altered Intercellular Communication | However, no correlation was found between the histological evidence and the degree of inflammation and neurological symptoms. | 24635921 |
| Inflammation, Neurologic Deficits, Pain Distress Question | Altered Intercellular Communication | However, the neuroradiological and histological evidence of peridiscal inflammation was not correlated with the severity of pain or sensorimotor deficits in our patients. | 24635921 |
| Inflammation, Intervertebral Disk Displacement | Altered Intercellular Communication | Additional research is needed because the occurrence of local inflammation may indicate an ongoing degradation of herniated fragments and thus be helpful in therapeutic decision-making. | 24635921 |
| Ulcer, Inflammation, Colitis | Altered Intercellular Communication | The extent of inflammation is a predictor for pouch-related complications in ileal pouches in patients with ulcerative or indeterminate colitis. | 24635999 |
| Inflammation | Altered Intercellular Communication | The presence of extension of the inflammation into the muscularis propria of the resected specimen was associated with an increased risk of pouch-related complications (P = 0.01). | 24635999 |
| Inflammation, Ulcerative Colitis | Altered Intercellular Communication | The extension of inflammation into the muscularis propria appears to predict pouch-related complications following restorative proctocolectomy for UC or IC. | 24635999 |
| Acute inflammation, Obesity | Altered Intercellular Communication | Obesity is associated with acute inflammation in a sample of adolescents. | 24636574 |
| Inflammation, Adolescent Obesity | Altered Intercellular Communication | To evaluate whether circulating neutrophils, markers of acute inflammation, are associated (quantitatively and qualitatively) with adolescent obesity and whether leptin modulates these associations. | 24636574 |
| Inflammation | Altered Intercellular Communication | Participants with increased adiposity had higher circulating neutrophil counts, suggesting acute inflammation. | 24636574 |
| Inflammation, Lung Diseases, Interstitial, Fibrosis Assessment | Altered Intercellular Communication | Interstitial lung diseases (ILDs) form a heterogeneous group of diseases with varying degrees of inflammation and fibrosis. | 24636811 |
| Inflammation, Carotid Intima-Media Thickness | Altered Intercellular Communication | In addition, inflammation models such as carotid intima-media thickness and serum inflammatory cytokines were analyzed in 58 taxi drivers with and without co-morbidity. | 24637182 |
| Inflammation, AHSG protein, human | Altered Intercellular Communication | Fetuin-A may contribute to exercise training-induced improvements in hepatic insulin resistance, CHO utilization, and inflammation in older obese adults. | 24637346 |
| Autoimmune Diseases, Inflammation, destruction joint | Altered Intercellular Communication | RA synovial fibroblasts (RASF) actively contribute to inflammation and joint destruction in this chronic inflammatory autoimmune disease. | 24638860 |
| Inflammation, Hemorrhage, Hypertrophy | Altered Intercellular Communication | Abnormal clinical presentation in Group A included altered pigmentation (35.6%), rapid enlargement (30.5%), keratotic changes (16.9%), inflammation (7.6%), ulceration (5.1%), and hemorrhage (4.2%). | 24638865 |
| Inflammation, Diabetes Mellitus | Altered Intercellular Communication | Animal studies link PAHs to inflammation and subsequent development of diabetes mellitus. | 24638887 |
| Inflammation, Nerve Degeneration | Altered Intercellular Communication | The objective of this paper is to determine whether progressive neurodegeneration occurs in MS eyes without clinically evident inflammation. | 24639478 |
| Inflammation | Altered Intercellular Communication | In RRMS eyes without clinically evident inflammation, progressive loss of RNFLT and GCIPT occurred, supporting the need for neuroprotection in addition to suppression of autoimmune responses and inflammation. | 24639478 |
| Bronchitis | Altered Intercellular Communication | Bronchial inflammation process in elderly patients (> 60 years) was characterized by significant higher content of neutrophils and lymphocytes as well as lower proportion of alveolar macrophages. | 24640699 |
| Chronic lymphocytic inflammation, Pontine structure, Clippers, Inflammatory disorder | Altered Intercellular Communication | Chronic lymphocytic inflammation with pontine perivascular enhancement responsive to steroids (CLIPPERS) is an inflammatory disease of the central nervous system that predominantly involves the pons and cerebellum and that improves with immunosuppressive treatment. | 24641246 |
| Cystic degeneration, Focal granulomatous inflammation | Altered Intercellular Communication | We report two cases of melanocytic matricoma in two elderly women with unusual histopathological features such as cystic degeneration and focal granulomatous inflammation, which are considered to be atypical for this entity. | 24641267 |
| Inflammation, Asthma | Altered Intercellular Communication | While clinically similar to eosinophilic asthma, patients with non-eosinophilic asthma have different responses to treatment and little is known about the triggers of symptoms and inflammation. | 24641293 |
| Inflammation, Chronic inflammatory disorder | Altered Intercellular Communication | To gain insight into the specificity of the psychophysiological stress response during chronic inflammation, we assessed autonomic and neuroendocrine responses to stress in different chronic inflammatory diseases. | 24641720 |
| Psoriasis | Altered Intercellular Communication | The altered neuroendocrine stress response in patients with psoriasis suggests that stressful events might have different physiological consequences for specific patient groups with chronic inflammatory conditions, possibly adversely affecting disease status. | 24641720 |
| Inflammation, Malignant Neoplasms | Altered Intercellular Communication | Recent studies have shown that the presence of systemic inflammation correlates with poor survival in various cancers. | 24641770 |
| Inflammation | Altered Intercellular Communication | the results suggest that GAG may be related to the ongoing process of inflammation and remodeling of the dysfunctional urothelium that is present in the PBS/IC. | 24642152 |
| Communicable Diseases, Inflammation, Febrile Neutropenia, CTCAE | Altered Intercellular Communication | Distinct inflammatory mediator patterns characterize infectious and sterile systemic inflammation in febrile neutropenic hematology patients. | 24642872 |
| Tissue damage, Inflammation, Infection, Fever, CTCAE | Altered Intercellular Communication | Invasive infections and sterile tissue damage can both give rise to systemic inflammation with fever and production of inflammatory mediators. | 24642872 |
| Communicable Diseases, Noncommunicable Diseases, Inflammation | Altered Intercellular Communication | We hypothesized that it would be possible to distinguish patterns of inflammatory mediators characterizing infectious and non-infectious causes of inflammation, respectively. | 24642872 |
| Inflammation, inflammation or infection | Altered Intercellular Communication | It is possible to separate patients with infectious inflammation from those with sterile inflammation based on inflammatory mediator patterns. | 24642872 |
| Inflammation, Cyclophosphamide/Vincristine/Dacarbazine Regimen, Cardiovascular Diseases | Altered Intercellular Communication | C-reactive protein (CRP) is a heritable biomarker of systemic inflammation and a predictor of cardiovascular disease (CVD). | 24643644 |
| Shock, Inflammation | Altered Intercellular Communication | Heat shock proteins (Hsp) are highly conserved immunomodulatory molecules upregulated when cells are exposed to stressful stimuli, such as inflammation. | 24643797 |
| Inflammation, Brain Injuries, Cerebral Ischemia | Altered Intercellular Communication | We show that infection-induced systemic inflammation mediates its effects via increasing platelet activation and microvascular coagulation in the brain after cerebral ischemia, as confirmed by reduced brain injury in response to blockade of platelet glycoprotein (GP) Iba. | 24644058 |
| Communicable Diseases, Inflammation, Atherosclerosis | Altered Intercellular Communication | S. pneumoniae infection augments atherosclerosis and exacerbates ischemic brain injury via IL-1 and platelet-mediated systemic inflammation. | 24644058 |
| Inflammation, Fracture | Altered Intercellular Communication | Fracture healing is an active process with early changes in bone and inflammation. | 24644096 |
| Inflammation, Ulcerative Colitis | Altered Intercellular Communication | These findings suggest that residual low-grade inflammation may influence the presence of IBS-like symptoms in UC patients in remission. | 24646420 |
| Balanitis, Chronic Kidney Diseases, Cardiovascular Diseases | Altered Intercellular Communication | Chronic kidney disease (CKD), characterized by senile inflammation, is a risk factor for cardiovascular disease. | 24646648 |
| Nephrosclerosis, Inflammation, Chronic Kidney Diseases | Altered Intercellular Communication | Coexistence of inflammation and conduit artery dysfunction may be closely related to renal small artery sclerosis in patients with CKD. | 24646648 |
| Inflammation, Primary malignant neoplasm, Hyperplasia | Altered Intercellular Communication | Observers also chose a final diagnosis from the categories of cancer, hyperplasia, inflammation, or normal. | 24646882 |
| Inflammation | Altered Intercellular Communication | Sphingolipids can alter synovial inflammation and the repair responses of damaged joints. | 24646942 |
| Inflammation, Acute myocardial infarction | Altered Intercellular Communication | Experimental studies showed that syndecan-1 is associated with inflammation in acute myocardial infarction and remodeling. | 24647119 |
| Inflammation, Fibrosis Assessment | Altered Intercellular Communication | Multivariable regression analyses showed a positive correlation between syndecan-1 levels and markers of fibrosis and remodeling but no correlation with inflammation markers. | 24647119 |
| Inflammation | Altered Intercellular Communication | Biomarkers of one-carbon metabolism are associated with biomarkers of inflammation in women. | 24647390 |
| Inflammation | Altered Intercellular Communication | Biomarkers of inflammation are associated with PLP, RBC folate, and homocysteine in women. | 24647390 |
| Periodontitis, Gastrointestinal mucositis | Altered Intercellular Communication | Periodontitis and radiation-induced oral mucositis are both inflammatory conditions which may be associated through a common underlying dysregulation of the inflammatory response. | 24647487 |
| Inflammation, Fat-free mass, Chronic Obstructive Airway Disease | Altered Intercellular Communication | To investigate the effects of elastic tubing training compared with conventional resistance training on the improvement of functional exercise capacity, muscle strength, fat-free mass, and systemic inflammation in patients with chronic obstructive pulmonary disease. | 24647863 |
| Inflammation, Malignant Neoplasms | Altered Intercellular Communication | Intermittent oxygen deficiency in cancers promotes prolonged inflammation, continuous angiogenesis, and increased drug resistance. | 24648344 |
| Inflammation | Altered Intercellular Communication | To better characterize this inflammatory response and to link inflammation to bone degradation, the local generation of proinflammatory and osteoclast-inducing cytokines was analysed, as was systemic T cell activation. | 24650243 |
| Inflammation, Cyclophosphamide/Vincristine/Dacarbazine Regimen, Cardiovascular Diseases | Altered Intercellular Communication | HIV-infected patients on antiretroviral therapy (ART) have an increased cardiovascular disease (CVD) risk as a result of heightened inflammation and immune activation, despite at times having normal lipids and few traditional risk factors. | 24650269 |
| Inflammation, HIV Infections | Altered Intercellular Communication | This study investigated the relationship between Lp-PLA2 and markers of CVD risk, systemic inflammation, immune activation, and coagulation in HIV infection. | 24650269 |
| Inflammation, Atherosclerosis | Altered Intercellular Communication | Subclinical atherosclerosis, endothelial function, inflammation, immune activation and fasting lipids were also evaluated. | 24650269 |
| Inflammation, Fibrosis Assessment | Altered Intercellular Communication | Novel fibrosis and inflammation markers in AF are correlated with atrial remodeling. | 24651058 |
| Inflammation, Fibrosis Assessment | Altered Intercellular Communication | Several unexplained mechanisms of atrial remodeling remain, but the present study has taken the first step in elucidating the mechanisms involving fibrosis and inflammation markers. | 24651058 |
| APP gene, Aortic Aneurysm, Abdominal | Altered Intercellular Communication | The pathogenesis of abdominal aortic aneurysm (AAA) is characterized to be inflammation-associated degeneration of vascular wall. | 24651519 |
| Inflammation, Primary lymphoid organ, Obesity | Altered Intercellular Communication | In animal model studies, obesity compromises the T-cell immune system as a result of enhanced adipogenesis in primary lymphoid organs and systemic inflammation. | 24651652 |
| Inflammation, Obesity | Altered Intercellular Communication | This population study suggests that obesity with enhanced inflammation is involved in aging of the human T-cell immune system. | 24651652 |
| Trachoma , Fibrosis Assessment, Infection, Conjunctivitis | Altered Intercellular Communication | Infections of the conjunctiva cause the blinding disease trachoma, an immuno-pathological disease that is characterised by chronic conjunctival inflammation and fibrosis. | 24651768 |
| Orbital Pseudotumor | Altered Intercellular Communication | Orbital inflammation is a potentially blinding and disfiguring disease process that is often treated with systemic corticosteroids and immunosuppression; better treatments are needed. | 24652467 |
| Orbital Pseudotumor | Altered Intercellular Communication | To determine whether rituximab, a monoclonal antibody against the B-lymphocyte antigen CD20, is effective in the treatment of refractory orbital inflammation. | 24652467 |
| Orbital Pseudotumor | Altered Intercellular Communication | Ten individuals with orbital inflammation refractory to systemic corticosteroids and at least 1 other immunosuppressive agent were enrolled from January 2007 to March 2010. | 24652467 |
| Inflammation | Altered Intercellular Communication | Initial responders with recurrent inflammation after week 24 were permitted reinfusion with an additional cycle of 2 open-label 1000-mg rituximab infusions. | 24652467 |
| Inflammation, orbit (eye disorders) | Altered Intercellular Communication | The primary outcomes were reduction of inflammation measured with a validated orbital disease grading scale and corticosteroid dose reduction by at least 50%. | 24652467 |
| Inflammation | Altered Intercellular Communication | Four patients who were positive responders at the week 24 end point experienced breakthrough inflammation after week 24 and received reinfusions between 24 and 48 weeks. | 24652467 |
| Noncommunicable Diseases, Orbital Pseudotumor | Altered Intercellular Communication | Rituximab was safe and effective in 7 of 10 patients with noninfectious orbital disease, although 4 required reinfusion with rituximab to maintain control of orbital inflammation. | 24652467 |
| Orbital Pseudotumor | Altered Intercellular Communication | Rituximab should be considered in the treatment of refractory orbital inflammation. | 24652467 |
| Facial paralysis, Palsy | Altered Intercellular Communication | Facial nerve palsy results in the loss of facial expression and is most commonly caused by a benign, self-limiting inflammatory condition known as Bell palsy. | 24652558 |
| Inflammation | Altered Intercellular Communication | Our data support the role of chronic inflammation in the development of ARMD. | 24654791 |
| Inflammation, Fibrosis Assessment | Altered Intercellular Communication | Light microscopy showed fibrosis with abundant collagen deposition but no inflammation in all patients. | 24655442 |
| Inflammation | Altered Intercellular Communication | A smouldering low-grade inflammation favouring low TGF-b1 concentrations is postulated as the primary pathological process leading to PHSD. | 24655442 |
| Inflammation, N-nitrosomorpholine, DGCR2 gene, Neuromyelitis Optica, Demyelinating Diseases | Altered Intercellular Communication | Neuromyelitis optica (NMO) is a serious inflammatory demyelinating disease (IDD), characterized by the inflammation and demyelination of optic nerves and spinal cords, which subsequently leads to the loss of function. | 24655566 |
| Fibrosis of pancreas, Pancreatitis, Pancreatic carcinoma, Pancreatitis, Chronic | Altered Intercellular Communication | Patients with chronic painful pancreatitis due to HGP with a high lifetime risk of pancreatic cancer should be considered earlier for TP-IAT before pancreatic inflammation results in a higher degree of pancreatic fibrosis and islet cell function loss. | 24655839 |
| Granuloma, Interstitial Fibrosis Assessment | Altered Intercellular Communication | All IGO cases had an epithelioid granulomatous reaction confined to seminiferous tubules, an extensive interstitial lymphoplasmacytic inflammation, 3 of 6 had prominent interstitial fibrosis, and 3 of 6 cases had plasma cells with an IgG4+/IgG+ ratio >40%. | 24656095 |
| Necrotizing granulomatous inflammation | Altered Intercellular Communication | Of the 4 UGO cases, most had predominantly interstitial with less intratubular granulomatous inflammation. | 24656095 |
| Inflammation, Myocarditis, CTCAE 5.0 | Altered Intercellular Communication | Myocarditis is defined as inflammation of the myocardium. | 24656318 |
| Inflammation, Fever, CTCAE, Hyperimmunoglobulinemia D | Altered Intercellular Communication | HIDS is clinically characterized by recurrent episodes of fever and inflammation. | 24656624 |
| Communicable Diseases, Carcinogenesis, Inflammation | Altered Intercellular Communication | Chronic inflammation and infection are major risk factors for gastric carcinogenesis in adults. | 24656654 |
| Virilization, CTCAE, Vaginal Hemorrhage, Hyperestrogenism | Altered Intercellular Communication | Only 2 demonstrated hormonal manifestations, with vaginal bleeding due to hyperestrogenism in the 7 month old, and virilization in an 11-year-old female. | 24656709 |
| Inflammation, Observation Method - Coagulation, Endotoxemia | Altered Intercellular Communication | In a human endotoxemia model, microparticles expressing procoagulant TF (MP-TF) are released in blood concurrently with markers of inflammation and coagulation. | 24657035 |
| Inflammation, Carotid Intima-Media Thickness, Fibrosis Assessment, Fatty degeneration, Non-alcoholic Fatty Liver Disease | Altered Intercellular Communication | Patients with procoagulant-imbalance detected as ETP-ratio greater or PICI% lower than the median value of controls tended to have a higher risk of metabolic-syndrome, higher intima-media thickness, fibrosis, steatosis or lobular inflammation, all considered clinical manifestations of NAFLD. | 24657400 |
| vascular inflammations, Aortic Aneurysm, Abdominal | Altered Intercellular Communication | Systemic vascular inflammation in abdominal aortic aneurysm patients: a contrast-enhanced PET/CT study. | 24658166 |
| Inflammation, Atherosclerosis, Aortic Aneurysm, Abdominal, APP gene, vascular inflammations | Altered Intercellular Communication | The aim of this paper was to investigate the presence of systemic vascular inflammation and its relationship with risk factors and biomarkers of systemic inflammation related to atherosclerosis in asymptomatic abdominal aortic aneurysm (AAA) patients. | 24658166 |
| vascular inflammations | Altered Intercellular Communication | The present findings support the relevance of systemic vascular inflammation in all phases of atherosclerosis-related disorders. | 24658166 |
| Inflammation, Acute vascular insufficiency of intestine (disorder) | Altered Intercellular Communication | Moreover they confirm the concept that acute ischemic syndromes might represent the local result of a systemic inflammation rather than the focal involvement of a single arterial lesion. | 24658166 |
| ARCN1 gene, Inflammation | Altered Intercellular Communication | Impaired CTLA-4 responses in COPD are associated with systemic inflammation. | 24658432 |
| Pain Distress Question, Inflammation, Complex Regional Pain Syndromes, Hyperalgesia | Altered Intercellular Communication | Complex regional pain syndrome (CRPS) is characterized by signs and symptoms of peripheral inflammation, which leads to peripheral neural sensitization associated most frequently (in about 70%) with blunt pressure hyperalgesia. | 24658473 |
| Metabolic Diseases, Hypopituitarism | Altered Intercellular Communication | Decreased level of consciousness in neonates may result from different etiologies, including rare metabolic and hormonal disorder due to anterior pituitary insufficiency. | 24658993 |
| Hypopituitarism | Altered Intercellular Communication | Given the clinical findings and decreased level of consciousness, hormonal diagnostic tests and brain CT scan were performed for any evidence of hypopituitarism. | 24658993 |
| Inflammation, Immune dysregulation | Altered Intercellular Communication | Furthermore, relationship strain with family, friends and spouses was associated with greater levels of emotion dysregulation and chronic inflammation. | 24659156 |
| Inflammation | Altered Intercellular Communication | Neutrophils play a key role in the inflammatory responses where movement of neutrophils toward the site of inflammation depends on CD11b/CD18 expression as adhesion molecules on these cells. | 24659162 |
| Heart Diseases, Inflammation | Altered Intercellular Communication | Recent studies have shown that neutrophil lymphocyte ratio (NLR) is a strong indicator in determining inflammation in cardiac and non-cardiac diseases. | 24659410 |
| Arterial Stiffness, Inflammation | Altered Intercellular Communication | The main outcome measures were arterial stiffness, endothelial function, biomarkers of inflammation and oxidative stress, and cardiometabolic risk factors. | 24659610 |
| Neurotoxicity Syndromes | Altered Intercellular Communication | Although its pathogenesis is not fully understood, it is postulated that direct damage of methotrexate to the central nervous system plays a major part and elevated levels of homocysteine and its excitatory amino acid neurotransmitter metabolites (homocysteic acid and cysteine sulfinic acid) could mediate, in part, MTX-associated neurotoxicity. | 24659737 |
| Sample Size Calculation, Fibrosis Assessment, Inflammation, Vascular Diseases | Altered Intercellular Communication | RDW in SSc may represent an integrative measure of multiple pathological processes including extensive vasculopathy, fibrosis or ongoing inflammation. | 24659752 |
| Inflammation, Rheumatoid Arthritis | Altered Intercellular Communication | Synovial inflammation assessed by ultrasonography correlates with MRI-proven osteitis in patients with rheumatoid arthritis. | 24659755 |
| Refractory anemias, Inflammation | Altered Intercellular Communication | The aim of this study was to explore whether assessment of synovial inflammation by ultrasonography correlates with MRI-proven osteitis in patients with RA. | 24659755 |
| Granulomatous inflammation | Altered Intercellular Communication | Initial fine needle aspiration cytology (FNAC) of the cervical lymph node was suggestive of granulomatous inflammation; the chest radiograph was normal. | 24660565 |
| Granulomatous inflammation, Sarcoidosis, Non-necrotizing granulomatous inflammation | Altered Intercellular Communication | This time an excision biopsy of the lymph node was done which revealed discrete, non-caseating, reticulin rich granulomatous inflammation suggestive of sarcoidosis. | 24660565 |
| Inflammation | Altered Intercellular Communication | FNAC from this lymph node showed caseating granulomatous inflammation and the stain for acid-fast bacilli was positive. | 24660565 |
| Inflammation, Tuberculosis | Altered Intercellular Communication | It was also more often found in the tuberculosis group than in the inflammation group (P < 0.01). | 24661424 |
| Pneumonitis, Tuberculosis | Altered Intercellular Communication | It may also help distinguish tuberculosis from other causes of lung inflammation. | 24661424 |
| Inflammation | Altered Intercellular Communication | Regular exercise training has been shown to reduce systemic inflammation, but there is limited research directly comparing different types of training. | 24662224 |
| Pain Distress Question | Altered Intercellular Communication | These were pain (median rating, 10), loss of joint motion (median rating, 9), work loss (median rating, 7), and joint inflammation/swelling (median rating, 8). | 24662554 |
| Inflammation | Altered Intercellular Communication | These radiologic abnormalities occurred in more advanced stages of the otovestibular deterioration, supporting the hypothesis that these lesions might represent the end phase of a low-grade chronic inflammation or protein deposition. | 24662630 |
| Meningioma | Altered Intercellular Communication | Somatostatin receptor-positive granulomatous inflammation mimicking as meningioma on simultaneous PET/MRI. | 24662657 |
| Necrotizing granulomatous inflammation, Meningioma | Altered Intercellular Communication | We report a case of a somatostatin receptor-positive extra-axial necrotizing granulomatous inflammation mimicking as meningioma on simultaneous Ga DOTATATE PET/MRI. | 24662657 |
| Inflammation, Primary malignant neoplasm, Inflammatory disorder | Altered Intercellular Communication | While macrophage migration inhibitory factor (MIF) has been extensively studied in the context of inflammation and inflammatory disorders, less work has been devoted to its involvement in cancer, notably in neoplastic progression. | 24663824 |
| Inflammation | Altered Intercellular Communication | Impairment of the ubiquitin-proteasome pathway in RPE alters the expression of inflammation related genes. | 24664704 |
| Retinitis | Altered Intercellular Communication | These data suggest that impairment of the UPP in RPE may be one of the causes of retinal inflammation and abnormal functions of monocyte and the complement system during the pathogenesis of age-related macular degeneration. | 24664704 |
| Vasculitis, Giant Cell Arteritis | Altered Intercellular Communication | Positron emission tomography assessment of large vessel inflammation in patients with newly diagnosed, biopsy-proven giant cell arteritis: a prospective, case-control study. | 24665112 |
| Giant Cell Arteritis, GCA gene | Altered Intercellular Communication | Positron emission tomography (PET) scan is emerging as a promising imaging technique to detect large-vessel inflammation in giant cell arteritis (GCA). | 24665112 |
| Sepsis, Inflammation | Altered Intercellular Communication | We investigated PON1 activity in surgical patients with sepsis in relation to oxidative stress status, inflammation, disease severity, and survival. | 24665146 |
| Communicable Diseases, Inflammation, Valvular endocarditis | Altered Intercellular Communication | Patients with early infection were more likely to be female, on anticoagulation, and present with localized inflammation, whereas those with late infection were more likely to have CIED erosion or valvular endocarditis. | 24665867 |
| Airway structure, Acid reflux | Altered Intercellular Communication | The results support an association between gastroesophageal reflux and upper airway inflammation. | 24665868 |
| prostatitis | Altered Intercellular Communication | Patients with prostate inflammation had a statistically significant higher grade of AGA, together with higher PSA. | 24665929 |
| prostatitis | Altered Intercellular Communication | A novel finding of our study is that BPH patients with prostate inflammation had a significantly higher grade of AGA together with significantly higher PSA levels. | 24665929 |
| Ulcerative Colitis, Inflammatory disease of mucous membrane | Altered Intercellular Communication | We have reported that second-generation colon capsule endoscopy (CCE-2) might be feasible for assessing the severity of mucosal inflammation in ulcerative colitis (UC). | 24666340 |
| Inflammation, Coronary Arteriosclerosis | Altered Intercellular Communication | Assessment of tissue oxygenation of periodontal inflammation in patients with coronary artery diseases using optical spectroscopy. | 24666796 |
| Inflammation, Systemic disease | Altered Intercellular Communication | This study supports the hypothesis that optical spectroscopy can determine the periodontal inflammation in patients with certain systemic disorders like CAD. | 24666796 |
| Non-Small Cell Lung Carcinoma | Altered Intercellular Communication | Prognostic performance of inflammation-based prognostic indices in primary operable non-small cell lung cancer. | 24667648 |
| Inflammation, CNS disorder | Altered Intercellular Communication | Whether it is associated with CNS disease or a marker of inflammation requires further investigation. | 24668125 |
| Prostate carcinoma | Altered Intercellular Communication | Higher levels of inflammation-associated cytokines correlate with poorer prostate cancer outcomes and may guide strategies to improve prostate cancer therapy. | 24668612 |
| Airway structure, Bronchopulmonary Dysplasia | Altered Intercellular Communication | Airway inflammation is involved in the pathogenesis of bronchopulmonary dysplasia (BPD). | 24668942 |
| Atherosclerosis, Sepsis, Hypercholesterolemia, Cerebrovascular accident, Chronic heart failure, Hypertension, CTCAE | Altered Intercellular Communication | High ADMA levels have been shown to be related with disorders causing vascular inflammation such as hypertension, hypercholesterolemia, atherosclerosis, chronic heart failure, stroke and sepsis. | 24669818 |
| Inflammation, Vasculitis, CTCAE | Altered Intercellular Communication | In addition, these data might suggest the higher ADMA levels in patients could be due to the perivascular inflammation and vasculitis in CA. | 24669818 |
| Inflammation | Altered Intercellular Communication | There was a positive correlation between increased sVCAM-1and reduced time required for walking 10 m. PPS might induce neurological improvement by inhibition of chronic inflammation in the spinal cord, through blocking the adhesion cascade by increasing serum sVCAM-1, in addition to rheological improvement of the microcirculation. | 24671717 |
| Inflammation, Erdheim-Chester Disease, Histiocytic syndrome | Altered Intercellular Communication | Erdheim-Chester disease (ECD) is a rare form of histiocytosis characterised by uncontrolled chronic inflammation. | 24671772 |
| Inflammation, Colitis | Altered Intercellular Communication | Diversion colitis is the inflammation of the excluded segment of the colon in patients undergoing ostomy. | 24672659 |
| Inflammation, ARIH1 wt Allele, Acute kidney injury | Altered Intercellular Communication | Oxidative stress and inflammation during cardiac surgery may be associated with acute renal injury (ARI). | 24672814 |
| Inflammation, Heart failure | Altered Intercellular Communication | Impaired resolution of inflammation in human chronic heart failure. | 24673112 |
| Sjogrens Syndrome", Inflammation | Altered Intercellular Communication | Ductal epithelial expression of Ro52 correlates with inflammation in salivary glands of patients with primary Sjogren's syndrome. | 24673429 |
| Psoriasis, Cyclophosphamide/Vincristine/Dacarbazine Regimen, Cardiovascular Diseases | Altered Intercellular Communication | Psoriasis is associated with increased risk of cardiovascular disease (CVD), possibly due to chronic low-grade systemic inflammation. | 24673617 |
| Fibrosis Assessment, Interstitial inflammation | Altered Intercellular Communication | The UIP pattern or upper lobe fibrosis is remarkably different from GIP in distribution of hard metal elements, associated interstitial inflammation and fibrosis, and clinical features. | 24674995 |
| Inflammation, Aneurysm | Altered Intercellular Communication | Both the fragility of the sinus of Valsalva and the residual inflammation could have caused the patient's aneurysm formation. | 24676407 |
| Inflammation, Necrosis | Altered Intercellular Communication | Inflammation as well as angiogenesis may participate in the pathophysiology of brain radiation necrosis. | 24676944 |
| Inflammation | Altered Intercellular Communication | Both angiogenesis and inflammation might be caused by the regulation of HIF-1a, which is well known as a transactivator of VEGF and of the CXCL12/CXCR4 chemokine axis. | 24676944 |
| Fibrosis Assessment, Hepatitis B, Hepatitis, Chronic | Altered Intercellular Communication | Pathological functions of interleukin-22 in chronic liver inflammation and fibrosis with hepatitis B virus infection by promoting T helper 17 cell recruitment. | 24677193 |
| Fibrosis Assessment, Hepatitis, Chronic, Hepatitis | Altered Intercellular Communication | In an HBV transgenic (Tg) mouse model of T-cell-mediated chronic liver inflammation and fibrosis, blockade of IL-22 attenuated hepatic expression of chemokine (C-X-C motif) ligand 10 and chemokine (C-C motif) ligand 20 (CCL20) and subsequently reduced Th17 recruitment and liver inflammation and fibrosis progression. | 24677193 |
| Fibrosis Assessment, Hepatitis, Chronic | Altered Intercellular Communication | IL-22 plays a pathological role in exacerbating chronic liver inflammation and fibrosis by recruiting hepatic Th17 cells in HBV-infected patients and HBV Tg mice. | 24677193 |
| Inflammation, Disease, Obesity | Altered Intercellular Communication | Obesity is a disorder often accompanied by a heightened state of systemic inflammation and immunoactivation. | 24678280 |
| Inflammation, Cerebrovascular accident | Altered Intercellular Communication | Subsequently VZV-induced inflammation within the affected cerebral arteries leads to occlusion and stroke. | 24678919 |
| Inflammation | Altered Intercellular Communication | Inflammaging, a state of chronic inflammation in the elderly, is now thought to be a key element of the ageing process and contributor to age-related disease. | 24679110 |
| Inflammation, Presbycusis | Altered Intercellular Communication | Inflammation is associated with a worsening of presbycusis: evidence from the MRC national study of hearing. | 24679110 |
| Inflammation | Altered Intercellular Communication | Inflammaging, a state of chronic inflammation in the elderly, is now thought to be a key element of the ageing process and contributor to age-related disease. | 24679110 |
| Inflammation, Fibrosis Assessment, kyphosis, Immobile, Spondylitis | Altered Intercellular Communication | Ankylosing spondylitis is a disease in which inflammation of joints, most often in the axial skeleton, can lead to reactive fibrosis and eventual joint fusion with associated immobility and kyphosis. | 24679210 |
| Aortic Valve Insufficiency, Uveitis | Altered Intercellular Communication | The disease often involves extra-articular features, such as uveitis and aortic regurgitation, as well as associated inflammatory conditions of the intestines. | 24679210 |
| Inflammation, Mucinous, Neoplasms, Fibrosis Assessment, Bronchioloalveolar Adenocarcinoma | Altered Intercellular Communication | Post-mortem lung biopsies gave a diagnosis of mucinous and non-mucinous bronchiolo-alveolar carcinoma with typical lepidic growth pattern of tumor cells and discrete septal thickening but no fibrosis, inflammation or local invasion. | 24680118 |
| Pleurisy | Altered Intercellular Communication | Twenty-two of 86 patients (25.5%) had a possible identifiable cause of pleural inflammation (benign disease). | 24681036 |
| Inflammation, Obesity | Altered Intercellular Communication | Obesity is associated with systemic inflammation, alterations in the intestinal microbiome, and decreased epithelial integrity. | 24681076 |
| Inflammation, Colorectal Neoplasms, Carcinogenesis | Altered Intercellular Communication | MC has a reduced risk of colorectal neoplasia, suggesting that this model of chronic inflammation plays a protective effect against colorectal carcinogenesis. | 24681653 |
| granulomatous uveitis, Nongranulomatous uveitis, Steroid-induced myopathy | Altered Intercellular Communication | Seventy percent of OHT in granulomatous uveitis cases was inflammation-induced, while 76.7% in non-granulomatous uveitis cases was steroid-induced. | 24682184 |
| granulomatous uveitis, Pupillary block, Uveitis | Altered Intercellular Communication | OHT in non-granulomatous uveitis was mainly steroid-induced open-angle OHT with some cases of angle-closure OHT caused by pupillary block, while that in granulomatous uveitis was mostly inflammation-induced open-angle OHT with no pupillary block-related angle-closure OHT. | 24682184 |
| Inflammation, Primary malignant neoplasm | Altered Intercellular Communication | Lipocalin-2 (Lcn-2) is expressed in human neutrophils and epithelial cells, particularly in the presence of inflammation or cancer. | 24682311 |
| Optic Neuritis | Altered Intercellular Communication | Abnormal nerve inflammation coexists and may play a role in pathogenesis. | 24682967 |
| Inflammation, Failure (biologic function) | Altered Intercellular Communication | When the cause of early implant failure was inflammation, the failure rate was significantly higher for implants in the anterior maxilla; implants with poor primary stability, a machined surface, or a length exceeding 15 mm; and implants placed with a reconstructive procedure and two-stage surgery. | 24683555 |
| Inflammation, Edema | Altered Intercellular Communication | Nasofibroscopic examination revealed a right arytenoid granuloma with oedema and inflammation, and bilateral arytenoid immobility. | 24683823 |
| Inflammation, Primary malignant neoplasm | Altered Intercellular Communication | The physiological factors underlying the association are complex, and they may relate to melatonin excretion patterns, low-grade inflammation in cancer development process or disruptions in circadian rhythmicity. | 24684747 |
| tyramine-deoxysorbitol, Avitaminosis, Erectile dysfunction | Altered Intercellular Communication | To evaluate whether hormonal markers predict erectile dysfunction (ED) and symptoms of T deficiency syndrome (TDS), which are commonly found in the population of infertile men. | 24684954 |
| Inflammation, Coronary Lesions Treated | Altered Intercellular Communication | Advanced coronary lesions with lipid cores are associated with adventitial inflammation, but the early inflammatory process in human coronary adventitia is largely unknown. | 24685316 |
| Respiratory Distress Syndrome, Adult, Inflammation, Pneumonia, Burn Specimen Source Codes | Altered Intercellular Communication | Smoke inhalation, pneumonia and inflammation process are the major causes of ARDS in burn patients. | 24685349 |
| Data types - Address | Altered Intercellular Communication | These findings support the assumption that specific NPS features in AD might be (in)directly related to brain region-specific monoaminergic neurotransmitter alterations. | 24685637 |
| Inflammation, Chronic disease | Altered Intercellular Communication | A Mediterranean diet (MD) has been associated with reduced inflammation and mortality for major chronic diseases. | 24687087 |
| Dyspnea, Lymphocyte count increased, Bronchiolitis, Interstitial inflammation | Altered Intercellular Communication | A 30-year-old, nonsmoking, female baker was referred for progressive dyspnea on exertion, basal crackles on auscultation, restrictive lung function, decreased diffusing capacity of the lung for carbon monoxide, ground glass hyperdensities with a mosaic pattern on high-resolution CT scan, 25% lymphocytosis by BAL, and cellular chronic bronchiolitis with peribronchiolar interstitial inflammation by lung biopsy specimen. | 24687706 |
| Arthritis, Cartilage damage, Gout | Altered Intercellular Communication | Exploring cartilage damage in gout using 3-T MRI: distribution and associations with joint inflammation and tophus deposition. | 24687845 |
| Inflammation | Altered Intercellular Communication | If the healing process does not take place within a reasonable timeframe, the possibility of a pathologic process beyond localized infection/inflammation should be suspected. | 24687889 |
| Intestinal metaplasia, Acute and chronic inflammation | Altered Intercellular Communication | Severe chronic cardia inflammation increased the presence of cardia intestinal metaplasia 6.2 fold (OR=6.288; p<0.0001). | 24689092 |
| Inflammation, Atherosclerosis | Altered Intercellular Communication | A state of chronic inflammation is shared by them all, YKL-40 also being involved in the severity of chronic endothelial inflammation, which today is considered of crucial importance for the development of atherosclerosis. | 24689875 |
| Refractory anemias, Inflammation | Altered Intercellular Communication | The importance of apolipoproteins in the development of CVEs, in the context of lipids, haemostatic factors, and inflammation, was evaluated over 18 years in patients with RA. | 24689997 |
| Inflammation, Tissue injury, Breast Carcinoma | Altered Intercellular Communication | These findings suggest that urinary ADAM 12 may not correlate directly with the status and stage of breast cancer as previously thought; rather these increases may be a result of tissue injury and inflammation from biopsy and surgical resection. | 24690292 |
| Inflammation, Periodontitis | Altered Intercellular Communication | Periodontitis involves periodontal tissue destruction and is associated with chronic inflammation and ageing. | 24690593 |
| Inflammation, Pericarditis, CTCAE, Disease | Altered Intercellular Communication | Pericarditis is a common human disease defined by inflammation of the pericardium. | 24690743 |
| Inflammation | Altered Intercellular Communication | Our findings suggest that an elevated S100A12 level could play a crucial role in systemic inflammation and may be a promising biomarker for predicting cardiovascular events and perioperative complications in patients with TAD. | 24691129 |
| Inflammation, Carotid Intima-Media Thickness | Altered Intercellular Communication | Among those with a CAC score of zero, T-cell activation and systemic inflammation correlated with carotid intima-media thickness and brachial hyperemic velocity, respectively. | 24691204 |
| Inflammation, Pancreatic carcinoma | Altered Intercellular Communication | Senescence-associated SIN3B promotes inflammation and pancreatic cancer progression. | 24691445 |
| Primary malignant neoplasm, Pancreatitis | Altered Intercellular Communication | Furthermore, evaluation of human pancreatic tissue and cancer cells revealed that Sin3B was decreased in control and PDAC samples, compared with samples from patients with pancreatic inflammation. | 24691445 |
| Inflammation | Altered Intercellular Communication | These results indicate that senescence-associated inflammation positively correlates with PDAC progression and suggest that SIN3B has potential as a therapeutic target for inhibiting inflammation-driven tumorigenesis. | 24691445 |
| Inflammation, Cerebrovascular accident | Altered Intercellular Communication | Complement activation and inflammation have been suggested in the pathogenesis of stroke; mannose-binding lectin (MBL) was found to have roles during the process. | 24691546 |
| Inflammation, Blood Clot | Altered Intercellular Communication | As evidence points towards an extensive "cross-talk" between the inflammatory and coagulation cascade, inflammation has been claimed as a possible mechanism through which different risk factors trigger venous thrombus formation. | 24691730 |
| Inflammation, Chronic heart failure | Altered Intercellular Communication | Elevated levels of serum sialic acid and high-sensitivity C-reactive protein: markers of systemic inflammation in patients with chronic heart failure. | 24693572 |
| Inflammation | Altered Intercellular Communication | Although it has been shown that inflammation occurs in HF, inflammatory markers have yet to be defined. | 24693572 |
| Inflammation, Chronic heart failure | Altered Intercellular Communication | Thus, TSA and hs-CRP would appear to be stable markers of systemic inflammation in chronic heart failure. | 24693572 |
| Inflammation, Hemorrhage, Gingival Hemorrhage | Altered Intercellular Communication | Both treatment groups experienced significant reductions in number of bleeding sites, gingival bleeding index (GBI), and gingival inflammation (MGI) relative to baseline (P < 0.001). | 24693625 |
| Inflammation, Hemorrhage, Obstruction, Meckel Diverticulum | Altered Intercellular Communication | Hemorrhage, obstruction and inflammation are the three main categories of complications resulting from Meckel's diverticulum. | 24693872 |
| Refractory anemias, Inflammation, ciliary vesicle | Altered Intercellular Communication | We sought to test the hypothesis that due to increased inflammation, CV disease and risk factors are associated with increased risk of future RA development. | 24693947 |
| Inflammation, Ascites | Altered Intercellular Communication | Continuous inflammation and ascites 10 months after the initiation of peritoneal dialysis. | 24694494 |
| palladium, Inflammation, Ascites | Altered Intercellular Communication | Based on these findings, in addition to the presence of continuous inflammation and ascites, a diagnosis of pre-encapsulating peritoneal sclerosis was suspected, and the treatment was switched from PD to hemodialysis. | 24694494 |
| Intraocular inflammation, Neurosyphilis, Vitelliform-like macular lesions | Altered Intercellular Communication | The patient received standard treatment for neurosyphilis with intravenous penicillin G. Two months later, the intraocular inflammation had resolved, but the resolution of the vitelliform lesions was more gradual. | 24695048 |
| Lymphoid neoplasm, Fibrosis Assessment, Liver damage, Cholestasis | Altered Intercellular Communication | INH was stopped, and she received N-acetyl cysteine and Vitamin K. Liver biopsy showed moderate to severe lymphocytic and plasmacytic portal and lobular inflammation, prominent ductal proliferation, moderate cholestasis (predominantly hepatocellular and canalicular), hepatocellular damage, and stage 3 bridging fibrosis. | 24695480 |
| Inflammation, Fibrosis Assessment, Liver damage, Cholestasis | Altered Intercellular Communication | Liver biopsy two years later showed mild portal inflammation, predominantly lymphocytitic, mild portal fibrosis without bridging, irregular bile ducts without cholestasis, and no significant hepatocellular damage; overall the later biopsy demonstrated significant improvement. | 24695480 |
| Hypophysitis, CTCAE, Inflammation, Primary malignant neoplasm | Altered Intercellular Communication | Hypophysitis is a chronic inflammation of the pituitary gland of unknown (primary forms) or recognizable (secondary forms) etiology, such as the use of ipilimumab in cancer immunotherapy. | 24695685 |
| Inflammation, Parakeratosis | Altered Intercellular Communication | Changes in parakeratosis, inflammation and dermal collagen remodelling were also observed. | 24696069 |
| Inflammation, Helicobacter pylori, Stomach Carcinoma, Carcinogenesis | Altered Intercellular Communication | Considerable progress has been made in understanding the roles of Helicobacter pylori in inflammation and gastric cancer; however, far less is known about the roles of enterohepatic Helicobacter species (EHS) in carcinogenesis and their zoonotic or pathogenic potential. | 24696515 |
| Inflammation, Intestinal Cancer, Diarrhea | Altered Intercellular Communication | These results suggest that EHS may represent an aetiological agent mediating diarrhoea, chronic inflammation, and possibly intestinal cancer in non-human primates, and may play a role in similar disease syndromes in humans. | 24696515 |
| Granulomatous inflammation, Necrosis | Altered Intercellular Communication | Interestingly, near to the malformed vessels, a large area of necrosis with granulomatous inflammation was found. | 24696743 |
| Chronic meningitis, Inflammation | Altered Intercellular Communication | Chronic meningitis is inflammation of the meninges where signs and symptoms develop and last for at least four weeks without alleviation. | 24696988 |
| Inflammation, Cardiovascular Diseases | Altered Intercellular Communication | Inflammation and immune activation have a crucial role in the pathogenesis of cardiovascular diseases. | 24697114 |
| Inflammation, Coronary Artery Disease | Altered Intercellular Communication | Our results are in line with a role of inflammation in coronary artery disease. | 24697114 |
| Presenile dementia, Inflammation | Altered Intercellular Communication | Compared with other studies of younger-old adults, this suggests that the effect of inflammation on dementia may differ in younger-old and the oldest-old individuals. | 24697580 |
| Inflammation, HIV Infections | Altered Intercellular Communication | How does monocyte metabolism impact inflammation and aging during chronic HIV infection? | 24697644 |
| Inflammation, Thyroid associated opthalmopathies | Altered Intercellular Communication | Six were excluded from further analysis due to relapse of their thyroid eye disease with increased inflammation. | 24697978 |
| Inflammation, Hepatocyte, Abnormal degeneration, Necrosis | Altered Intercellular Communication | Histological examination showed that liver cell edema, degeneration, necrosis, and inflammation were significantly relieved at 3, 6, and 12 months after transplantation. | 24698673 |
| Inflammation, Metabolic Syndrome X | Altered Intercellular Communication | Metabolic syndrome and inflammation were also more common in young CAD patients than in non-CAD patients. | 24698677 |
| Inflammation, Edema | Altered Intercellular Communication | The clinically visible grooves and large edematic papillae clustered on the region of the fissures might be caused by the inflammation and edema underneath the epithelium. | 24698850 |
| Retinal Pigments, Inflammatory abnormality of the eye | Altered Intercellular Communication | Ocular inflammation and endoplasmic reticulum stress are attenuated by supplementation with grape polyphenols in human retinal pigmented epithelium cells and in C57BL/6 mice. | 24699803 |
| Inflammation, Diabetic Retinopathy | Altered Intercellular Communication | Inflammation and endoplasmic reticulum (ER) stress are common denominators for vision-threatening diseases such as diabetic retinopathy and age-related macular degeneration. | 24699803 |
| Inflammatory abnormality of the eye | Altered Intercellular Communication | In this study, we hypothesized that MGPs would also be effective in attenuating ocular inflammation and ER stress. | 24699803 |
| Inflammatory abnormality of the eye | Altered Intercellular Communication | Consistently, acute ocular inflammation and leukocyte infiltration were almost completely dampened (>95%) by MGP supplementation (100-200 mg/kg body weight) in C57BL/6 mice. | 24699803 |
| Inflammatory abnormality of the eye | Altered Intercellular Communication | Collectively, we have demonstrated that MGP is effective in attenuating ocular inflammation and ER stress. | 24699803 |
| Inflammation, Inflammatory disorder | Altered Intercellular Communication | Systemic inflammation in patients with inflammatory joint diseases does not influence statin dose needed to obtain LDL cholesterol goal in cardiovascular prevention. | 24699940 |
| Rheumatoid Arthritis, Inflammation | Altered Intercellular Communication | There is a lipid paradox in rheumatoid arthritis describing that despite low lipids related to systemic inflammation, there is an increased cardiovascular (CV) risk. | 24699940 |
| Inflammation, Inflammatory disorder | Altered Intercellular Communication | Our aim was to evaluate if baseline lipid levels or baseline systemic inflammation were associated with the statin dose sufficient to achieve lipid targets in patients with inflammatory joint diseases. | 24699940 |
| Inflammation, Inflammatory disorder | Altered Intercellular Communication | Whether the background inflammation in patients with inflammatory joint diseases over time influences the CV risk reduction related to statins is yet unknown. | 24699940 |
| Inflammation | Altered Intercellular Communication | Interleukin (IL) 17A is an inflammatory cytokine expressed by Th 17 cells and plays a role in tissue inflammation by inducing release of proinflammatory and neutrophil-mobilizing cytokines. | 24699997 |
| Intraocular inflammation, Mass in iris, Pupil | Altered Intercellular Communication | Anterior examination of the right eye revealed a vascularised iris mass causing pupillary distortion, intraocular inflammation and raised intraocular pressure. | 24700045 |
| Therapeutic immunosuppression, Inflammation, Cardiovascular Diseases, Immune System Diseases, Infection, Chronic Kidney Diseases | Altered Intercellular Communication | CKD is associated with a complex state of immune dysfunction characterized by immune depression, predisposing patients to infections, and immune activation, resulting in inflammation that associates with higher risk of cardiovascular disease. | 24700875 |
| Pain Distress Question, Inflammation | Altered Intercellular Communication | He initially had pain and inflammation and was treated with immobilization for two weeks. | 24701775 |
| Pain Distress Question, Inflammation | Altered Intercellular Communication | Pain and inflammation persisted so plain films and MRI were ordered and they showed a lesion of the medial meniscus. | 24701775 |
| Intraocular inflammation, Corneal edema | Altered Intercellular Communication | In all cases corneal edema and intraocular inflammation ceased after vitrectomy. | 24701817 |
| Intraocular inflammation | Altered Intercellular Communication | Removal of retained intraocular lens fragments suspended the intraocular inflammation and normalized intraocular pressure in all cases. | 24701817 |
| Inflammation, Hypoxia | Altered Intercellular Communication | We observed that hypoxia treatment increased oxidative stress, exacerbated inflammation, and aggravated learning defects in aged APP/PS1 mice. | 24702189 |
| Inflammation, Colonization, Data types - Address, Exacerbation of cGVHD, Pruritus | Altered Intercellular Communication | The results of the study indicate that the 1-week stand-alone application of an emollient, tailored to target inflammation, pruritus, compromised barrier function and pathogenic bacterial colonization may offer benefit for the improvement of mild to moderately severe localized flares of AD. | 24702445 |
| Cataract, Inflammation | Altered Intercellular Communication | Femtosecond laser-induced macular changes and anterior segment inflammation in cataract surgery. | 24702572 |
| Airway structure | Altered Intercellular Communication | Airway inflammation correlates negatively with deep inhalation bronchoprotection against direct stimuli like methacholine. | 24702886 |
| Airway structure | Altered Intercellular Communication | We hypothesised that deep inhalation bronchoprotection to methacholine would be absent and airway inflammation would be present in individuals with AHR to inhaled mannitol. | 24702886 |
| Inflammation, Acute-On-Chronic Liver Failure | Altered Intercellular Communication | Systemic inflammation is associated with increased intrahepatic resistance and mortality in alcohol-related acute-on-chronic liver failure. | 24703488 |
| Multiple Organ Failure, Inflammation, Acute-On-Chronic Liver Failure, CRNKL1 wt Allele, Liver Cirrhosis | Altered Intercellular Communication | Acute-on-chronic liver failure (ACLF) is characterized by acute deterioration of cirrhosis, systemic inflammation and multi-organ failure. | 24703488 |
| Inflammation, Hypertension, CTCAE | Altered Intercellular Communication | Inflammation is also key to the pathobiology of portal hypertension. | 24703488 |
| Multiple Organ Failure, Inflammation, CRNKL1 wt Allele | Altered Intercellular Communication | The disturbances in systemic and hepatic haemodynamics in alcohol-related ACLF are associated with dysregulated inflammation, multi-organ failure and marked activation of the sympathetic nervous system. | 24703488 |
| Data types - Address | Altered Intercellular Communication | Here we demonstrate AD is a proinflammatory modulator and indicate that MMP-independent mechanisms may play a role downstream of AD-induced inflammatory signaling in dysfunctional vascular remodeling. | 24703604 |
| Inflammation, Peripheral Arterial Diseases | Altered Intercellular Communication | Gender and racial differences in endothelial oxidative stress and inflammation in patients with symptomatic peripheral artery disease. | 24703977 |
| Bladder Neoplasm, Inflammation, Cystitis, Calculi, Urethral Stenosis | Altered Intercellular Communication | Most had a negative cystoscopy finding, whereas in 67 of 185 (36.2%), the findings included bladder tumors in 18 (27%), hypervascularity in 18 (27%), radiation cystitis in 13 (19.4%), inflammation in 7 (10.4%), urethral stricture in 5 (7.5%), and calculus disease in 6 (8.9%). | 24704325 |
| Communicable Diseases, Granulomatous inflammation, Diarrhea, Chronic Active Colitis, Syndrome, Graft-vs-Host Disease | Altered Intercellular Communication | Cord colitis syndrome after umbilical cord blood transplantation (UCBT) involves late-onset diarrhea, absence of infection or GVHD, chronic active colitis, and granulomatous inflammation that responds to antibiotics. | 24704386 |
| Inflammation, Metabolic Syndrome X, Atherosclerosis, Diabetes Mellitus, Obesity | Altered Intercellular Communication | Chronic inflammation closely associates with obesity, metabolic syndrome, diabetes mellitus, and atherosclerosis. | 24705587 |
| Inflammation, Ulcer | Altered Intercellular Communication | Specifically, we investigated whether nutrition supply or inflammation affects the serum albumin level in 82 patients with pressure ulcers(s) (29 in whom pressure ulcer was present upon admission and 53 in whom pressure ulcer developed after hospital admission). | 24705743 |
| Pressure Ulcer, Inflammation | Altered Intercellular Communication | The serum albumin level appears to reflect inflammation, wound healing, and disease severity rather than nutrition supply in patients with pressure ulcer. | 24705743 |
| Inflammation | Altered Intercellular Communication | In joints with positive SV, changes in structural alteration did not relate to total SV values, which reflect total exposure to inflammation in an observational period. | 24706991 |
| Hepatic, Inflammation | Altered Intercellular Communication | The activity of periportal and lobular inflammation was scored 0 (none or minimal activity) to 4 (severe), and the degree of hepatitic rosette formation and emperipolesis was semiquantatively scored 0-3. | 24707143 |
| Inflammation, Hepatitis, FAM126A gene | Altered Intercellular Communication | Study findings are in accordance with the hepatocellular carcinogenic model where IL28B TT genotype, by promoting a persistent chronic hepatitis which leads to both hepatocyte injury and chronic inflammation, could facilitate HCC development. | 24707497 |
| Sepsis, Inflammation, Injury of kidney | Altered Intercellular Communication | In vivo EPC administration in sepsis increased plasma IL-10, suppressed lung vascular leakage, attenuated liver and kidney injury, and augmented miR-126 and -125b expression, which regulate endothelial cell function and/or inflammation. | 24707934 |
| Acute chest pain | Altered Intercellular Communication | EFN is a benign inflammatory condition frequently overlooked in the ED by physicians and radiologists but is an important factor in the differential diagnosis of patients with acute chest pain. | 24707937 |
| anaphylaxis, Chronic inflammation | Altered Intercellular Communication | Our report may provide a potentially effective therapeutic approach for the first time to other LP patients who are experiencing recurrent anaphylaxis and/or chronic inflammation. | 24708644 |
| Inflammation, Gout | Altered Intercellular Communication | Gout is characterized by episodes of intense joint inflammation in response to intra-articular monosodium urate monohydrate (MSU) crystals. | 24708712 |
| Inflammation, Fever, CTCAE, Hereditary | Altered Intercellular Communication | Hereditary periodic fever syndromes (HPFS) are rare diseases characterised by recurrent, self-limited episodes of fever and localised inflammation, which arise from monogenic defects. | 24708999 |
| Perineural spread, Inflammation, Tumor Cell Invasion | Altered Intercellular Communication | Of 239 patients (48%) with nerve invasion, 174 (73%) had perineural invasion, 65 (27%) intraneural invasion, and 37 (15%) perineural inflammation. | 24710845 |
| Communicable Diseases, Inflammation | Altered Intercellular Communication | They are related to intestinal energy, motility, and transport and to protective effects against infection and inflammation. | 24711120 |
| Inflammation, MS gene | Altered Intercellular Communication | Evaluating microglial activation with TSPO-binding PET ligands provides a unique tool to assess diffuse brain inflammation and perilesional activity in progressive multiple sclerosis in vivo. | 24711650 |
| Inflammation | Altered Intercellular Communication | Histology of the muscle showed non-specific inflammation of the external and internal oblique muscles. | 24711865 |
| Inflammation, Atrial Fibrillation by ECG Finding | Altered Intercellular Communication | As inflammation and oxidative stress were makedly encountered in the etiology, high cholesterol was also defined to provoke atrial fibrillation. | 24712763 |
| Inflammation, Fibrosis Assessment, Neoplasms, FAM126A gene | Altered Intercellular Communication | The proportion of CLC was significantly correlated with the degree of fibrosis (P < 0.01) and inflammation (P < 0.01), and inversely correlated with tumour size (P < 0.01) and histological grading of HCC (P < 0.05). | 24712771 |
| Deficiency of butyryl-CoA dehydrogenase, Connective Tissue Diseases, Vasculitis, CTCAE | Altered Intercellular Communication | Non-atherosclerotic SCAD is clearly associated with connective tissue disorders, vasculitis, and the peripartum period with its hormonal and haemodynamic changes. | 24712892 |
| Inflammation, Cholangitis | Altered Intercellular Communication | Patients with cholangitis may exhibit repeated and chronic inflammation of the biliary tract despite successful medical or surgical treatments. | 24713207 |
| Inflammation, Hemolysis (biological function) | Altered Intercellular Communication | Laboratory tests were consistent with haemolysis and inflammation. | 24713708 |
| Oculogyric crisis, Floppy infant syndrome, Diarrhea, Disturbance | Altered Intercellular Communication | In view of his infantile-onset hypotonia, oculogyric crises, and protracted diarrhoea, an autonomic disturbance related to neurotransmitters was suspected. | 24714172 |
| Refractory anemias, Rheumatoid Arthritis, Rheumatic Fever, Inflammation | Altered Intercellular Communication | Rheumatoid arthritis (RA) is a chronic, autoimmune, systemic and inflammatory rheumatic disease that leads to inflammation of the joints and surrounding tissues. | 24714506 |
| Autoimmune Diseases, Inflammation | Altered Intercellular Communication | Aged JKAP-knockout mice spontaneously develop inflammation and autoimmunity. | 24714587 |
| Inflammation, Atherosclerosis | Altered Intercellular Communication | Systemic inflammation and brachial artery endothelial function in the Multi-Ethnic Study of Atherosclerosis (MESA). | 24714919 |
| Inflammation, Endothelial dysfunction, Atherosclerosis | Altered Intercellular Communication | Inflammation and endothelial dysfunction have been implicated in the pathogenesis of atherosclerotic vascular disease. | 24714919 |
| vascular inflammations, Atherosclerosis | Altered Intercellular Communication | Elevated IL-6 levels may reflect a state that promotes vascular inflammation and development of subclinical atherosclerosis independent of traditional cardiovascular risk factors. | 24714919 |
| Inflammation | Altered Intercellular Communication | Low bone mineral density in young individuals is associated with greater gingival inflammation and recession. | 24715239 |
| Inflammation, Secondary osteoporosis, Gingival Hemorrhage | Altered Intercellular Communication | Significantly higher gingival recession (GR), gingival bleeding time index, and hence gingival inflammation were noted in patients with secondary osteoporosis compared to healthy subjects. | 24715239 |
| Inflammation | Altered Intercellular Communication | In conclusion, low BMD in young individuals was associated with greater gingival inflammation and recession when compared to those individuals with normal BMD values. | 24715239 |
| Inflammation, Nodular lesions, teratologic | Altered Intercellular Communication | Nodular lesions or masses were the most common anomalies detected during computed tomography scans, but disseminated inflammation and interstitial changes were also seen. | 24715630 |
| Inflammation | Altered Intercellular Communication | There is some evidence suggesting a relationship between inflammation and VSA. | 24716416 |
| Inflammation, Endothelial dysfunction | Altered Intercellular Communication | We sought to demonstrate the relationship between high-sensitivity c-reactive protein (hs-CRP), a sensitive marker of inflammation, and the asymmetric dimethylarginine (ADMA)-induced endothelial dysfunction pathway in patients with VSA. | 24716416 |
| Inflammation | Altered Intercellular Communication | Six hours later, subjects underwent bronchoalveolar lavage (BAL) to quantify markers of alveolar inflammation and cell-specific injury. | 24716610 |
| Malignant neoplasm of urinary bladder, Inflammation, Granuloma | Altered Intercellular Communication | Prognostic value of inflammation or granuloma after intravesival BCG in non-muscle-invasive bladder cancer. | 24717097 |
| Malignant neoplasm of urinary bladder, Inflammation, Granuloma | Altered Intercellular Communication | To evaluate the prognostic value of inflammation or granuloma after intravesical bacille Calmette-Guerin (BCG) treatment in non-muscle-invasive bladder cancer (NMIBC). | 24717097 |
| Granuloma, Inflammation | Altered Intercellular Communication | Granuloma was identified in 60 patients and inflammation in 125 patients. | 24717097 |
| Granuloma, Inflammation | Altered Intercellular Communication | The progression-free survival rate was higher in the granuloma and inflammation groups (75 months [95% CI: 71-79] and 82 months [95% CI: 78-86], respectively) compared with the normal histology group (33 months [95% CI: 17-48]; log-rank P < 0.001). | 24717097 |
| Inflammation, Granuloma | Altered Intercellular Communication | Inflammation or granuloma in histology samples after intravesical BCG treatment for NMIBC are positive markers of response and their absence increases the risk of recurrence and progression. | 24717097 |
| Inflammation, Coronary Artery Disease, Aortic Valve Stenosis | Altered Intercellular Communication | Interleukin-6 receptor (IL-6R) gene Asp358Ala (A>C, rs2228145) polymorphism has been associated with lower circulating inflammation biomarkers in coronary artery disease (CAD), such as C-reactive protein (CRP) or fibrinogen, but its role in the pathogenesis of aortic valve stenosis (AS) remains unknown. | 24717336 |
| Airway structure, Pathogenesis | Altered Intercellular Communication | Pathogenesis is poorly understood, but excess neutrophilic airway inflammation is seen. | 24717640 |
| Sepsis, Inflammation, Pleural Infection, Pneumonia | Altered Intercellular Communication | However, such hospital caseload-outcome relationship (HCOR) has been seldom addressed in rare medical conditions, such as pleural infection, which is usually associated with pneumonia and may progress to systemic inflammation and severe sepsis. | 24717777 |
| Inflammation, Nasal Polyps, Inflammatory disorder | Altered Intercellular Communication | Nasal polyposis (NP) is a chronic inflammatory disease and the waste products of this inflammation are reactive oxygen species composed of free radicals. | 24717866 |
| Inflammation, MS4A2 wt Allele | Altered Intercellular Communication | The rural environment seems to protect from atopy, but its relation with nonatopic airway inflammations has been less investigated. | 24717869 |
| Nasal Polyps, Acute sinusitis | Altered Intercellular Communication | Nasal polyposis is a chronic inflammation of nasal and paranasal sinuses in the pathogenesis of which adhesion molecules may have a significant role. | 24717873 |
| Inflammation, Chronic sinusitis, Craniosynostosis | Altered Intercellular Communication | Chronic rhinosinusitis (CRS) mucosal inflammation is characterized by an accumulation of effector-memory T cells, but their immune regulatory potential has not been adequately examined. | 24717938 |
| Inflammation, Craniosynostosis, Allergy - Charge Type Reason | Altered Intercellular Communication | A higher percentage of CD4Treg and activated T-helper cells in CRS mucosa suggests increased inflammation in CRS, independent of the presence of allergy, microbial culture results, or eosinophilic mucus. | 24717938 |
| Inflammation, Neoplasms | Altered Intercellular Communication | The inflammatory healing process after tumor surgery differs from CRS inflammation and may explain the observed findings. | 24717955 |
| Mucous Membrane | Altered Intercellular Communication | In the other cases, the endoscopic findings were mucosal defect (18 %), redness/inflammation (16 %), suspicion for gastric heterotopia (5 %) and scar (3 %). | 24718939 |
| Arthralgia, Inflammation, Refractory anemias | Altered Intercellular Communication | Previous imaging studies in the arthralgia phase have shown that inflammation precedes RA development. | 24718962 |
| Arthritis | Altered Intercellular Communication | It is unknown which symptoms/characteristics relate to subclinical joint inflammation as measured by MRI. | 24718962 |
| Synovitis, Inflammation, Tenosynovitis | Altered Intercellular Communication | Symptoms and signs were related to MRI inflammation (based on MRI scores in symptom-free controls; a sum of synovitis, BME and tenosynovitis scores >=3 was considered positive). | 24718962 |
| Inflammation | Altered Intercellular Communication | Patients with MRI inflammation were older and were more frequently positive for anti-citrullinated peptide antibodies than patients without MRI inflammation (p<0.001 and 0.049). | 24718962 |
| Inflammation | Altered Intercellular Communication | A combination of symptoms/characteristics incompletely differentiated patients with and without MRI inflammation. | 24718962 |
| Autoimmune Diseases, Inflammation, Colorectal Carcinoma | Altered Intercellular Communication | The risk of damage by colorectal cancer (CRC) may increase due to autoimmune disease and cryptogenic inflammation. | 24719038 |
| Inflammation | Altered Intercellular Communication | This study showed that the IFP has a potential role in the induction of synovial inflammation in patients with severe knee OA. | 24719336 |
| Inflammation, Obesity | Altered Intercellular Communication | Efforts to reduce obesity and inflammation in this group may help correct abnormal levels of hsCRP and lipids. | 24719979 |
| Crohn Disease, Inflammation, Ulcerative Colitis | Altered Intercellular Communication | Serum NGAL levels in Crohn's disease and ulcerative colitis children did not correlate with age, gender, disease activity, and indices of the inflammation. | 24720485 |
| Inflammation, Demographics Domain, Chronic Kidney Diseases, Diabetes Mellitus | Altered Intercellular Communication | Inflammation may contribute to the high cardiovascular risk in diabetes mellitus (DM) and chronic kidney disease (CKD). | 24720535 |
| Inflammation, Congestive heart failure | Altered Intercellular Communication | Inflammation has been designated as a therapeutic target in CHF. | 24720919 |
| Primary malignant neoplasm, Neoplasms | Altered Intercellular Communication | This work expands what is known on the non-macrophage functions of CSF-1R and its role in solid tumors, and suggests that CSF-1R signaling may have a critical pathogenic role in a prototypical, inflammation-related cancer such as MPM and therefore may represent a promising target for therapeutic intervention. | 24722292 |
| Inflammation, Endothelial dysfunction | Altered Intercellular Communication | The effects of stress at work and at home on inflammation and endothelial dysfunction. | 24722508 |
| Inflammation, Cardiovascular Diseases | Altered Intercellular Communication | This study examined whether stress at work and at home may be related to dysregulation of inflammation and endothelial function, two important contributors to the development of cardiovascular disease. | 24722508 |
| Inflammation, Endothelial dysfunction | Altered Intercellular Communication | While lack of findings related to inflammation are somewhat surprising, if replicated in future studies, these findings may suggest that endothelial dysfunction is an important biological mechanism linking stress at work with cardiovascular health outcomes in men. | 24722508 |
| Airway structure | Altered Intercellular Communication | The exhaled breath temperature (EBT) has been proven to be the expression of airways inflammation as well as of the increased vascularity. | 24722795 |
| Bacteremia, Inflammation, Aortitis | Altered Intercellular Communication | CT and PET scans revealed an aneurysmatic soft tissue inflammation which was interpreted as infectious aortitis in the context of salmonella bacteraemia. | 24722933 |
| APP gene, Inflammation, Aortic Aneurysm, Abdominal | Altered Intercellular Communication | Systemic inflammation and increased matrix metalloproteinase (MMP) cause elastin degradation leading to abdominal aortic aneurysm (AAA) expansion. | 24726061 |
| melanoma, Lymphoma, Hamartoma, Lesion, Merkel cell carcinoma, Orbital Pseudotumor | Altered Intercellular Communication | The histologic subtype was idiopathic orbital inflammation in 2 lesions, lymphoma in 2, Merkel cell carcinoma in 1, hamartoma in 1 and 1 malignant melanoma. | 24726395 |
| Inflammation, Pelvic Pain | Altered Intercellular Communication | Pelvic pain and inflammation were assessed in the presence or absence of PAR2 expression and upon PAR2 neutralization. | 24726923 |
| Dental Plaque | Altered Intercellular Communication | Serum lipids associated with inflammation-related PET-FDG uptake in symptomatic carotid plaque. | 24727313 |
| Inflammation, Carotid Stenosis | Altered Intercellular Communication | We hypothesized that serum lipids, which experimental data suggest may be key initiators of carotid plaque inflammation, would be associated with plaque inflammation on (18)fluorodeoxyglucose (FDG)-PET in patients with acutely symptomatic carotid stenosis. | 24727313 |
| Inflammation, Dental Plaque, Rupture | Altered Intercellular Communication | Serum LDL and total cholesterol were associated with acutely symptomatic carotid plaque FDG uptake, supporting experimental data suggesting lipids may promote plaque inflammation, mediating rupture and clinical events. | 24727313 |
| Inflammation | Altered Intercellular Communication | However, the rs12692386 G ADAM17 allele is correlated with a higher expression of ADAM17 mRNA, which may play a role in increasing inflammation in IS patients. | 24727681 |
| Sepsis, Inflammation, Pulmonary Edema, CTCAE, Malignant Neoplasms | Altered Intercellular Communication | High-dose interleukin 2 therapy (HDIL-2) is an important protocol for advanced malignancies but is limited by systemic inflammation and pulmonary edema that is indistinguishable from sepsis. | 24727870 |
| Inflammation | Altered Intercellular Communication | All patients with acute local or systemic inflammation were excluded. | 24728515 |
| Inflammation, Anastomotic Leak | Altered Intercellular Communication | A preexisting low-grade inflammation represented by infiltrates of macrophages and neutrophils is a predictor for increased risk of developing colon anastomotic leakage. | 24728515 |
| Sepsis, Brain Injuries, Necrotizing Enterocolitis | Altered Intercellular Communication | IAIPs attenuate brain damage in young and adult subjects, decrease during sepsis and necrotizing enterocolitis in premature infants, and attenuate sepsis-related inflammation in newborn rats. | 24728724 |
| ARCN1 gene, Inflammation, Diabetes Mellitus, Non-Insulin-Dependent, Disease | Altered Intercellular Communication | The association with type 2 diabetes mellitus was greater in patients with COPD respect to general population, and correlated with the increase in BMI and the presence of other comorbidities, suggesting that both diseases may be targets of systemic inflammation. | 24728837 |
| Vascular lesions, Arteritis | Altered Intercellular Communication | Since then he has been neurologically asymptomatic and control imaging showed only residual intracranial left VA stenosis, with no signs of temporal artery inflammation or new vascular lesions. | 24728901 |
| Communicable Diseases, Inflammation | Altered Intercellular Communication | It can spread via cerebral circulation to the central nervous system as a manifestation of a disseminated infection; particularly in patients with immune suppression, which can result in isolated ring-enhancing lesions and inflammation in the brain. | 24730375 |
| Macrovesicular hepatic steatosis, Inflammation, Balloon Dilatation | Altered Intercellular Communication | The livers of DIAR-MSG mice showed macrovesicular steatosis, lobular inflammation with neutrophils, and ballooning degeneration after 29 weeks. | 24730643 |
| Fibrosis Assessment, Hepatic inflammation, FAM126A gene | Altered Intercellular Communication | SF level, possibly reflecting the degree of hepatic inflammation and fibrosis, is a negative risk factor for survival and recurrence after percutaneous RFA in HCC patients. | 24731153 |
| Cessation of life, Inflammation, Tissue Factor | Altered Intercellular Communication | Under persistent stress, death and proliferation are mutually promoted and form the vicious circle that triggers, maintains, and augments the inflammation and progression of TF. | 24731510 |
| Inflammation, Fibrosis Assessment | Altered Intercellular Communication | Moreover, the vicious circle may be universal, underlying the development of inflammation and fibrosis in various organs and tissues. | 24731510 |
| Inflammation, Hyperphosphatemia, CTCAE, Diabetes Mellitus, Calcification of the aorta, Chronic Kidney Diseases | Altered Intercellular Communication | Hyperphospatemia, chronic inflammation, diabetes, and decreased GFR are associated significantly with the presence of aortic calcification in non-dialysis CKD patients. | 24732137 |
| Inflammation, Comorbidity | Altered Intercellular Communication | Longitudinal changes in NT-proBNP are associated with changes in inflammation, nutritional status, age and comorbidity. | 24732340 |
| Inflammation | Altered Intercellular Communication | Similarly, greater PA indices were also independently associated with a lower level of inflammatory cytokine z score as an index of overall inflammation. | 24732722 |
| Pathogenic organism | Altered Intercellular Communication | Inflammation derived from pathogen infection involves the activation of toll-like receptor (TLR) signaling. | 24733511 |
| Inflammation | Altered Intercellular Communication | Understanding the mechanism of AGE-mediated signaling leading to these consequences, like oxidative stress, inflammation, apoptosis, etc. | 24733604 |
| Inflammation, Primary malignant neoplasm | Altered Intercellular Communication | The theory that chronic inflammation leads to cancer is well documented. | 24734318 |
| Adult T-Cell Lymphoma/Leukemia, Inappropriate ADH Syndrome | Altered Intercellular Communication | Syndrome of inappropriate antidiuretic hormone secretion associated with adult T-cell leukaemia/lymphoma. | 24735057 |
| Airway structure, Asthma | Altered Intercellular Communication | In subjects with moderate asthma who use ICS regularly, inhaled budesonide caused a transient dose-dependent vasoconstriction in the airway, thereby reversing one manifestation of airway inflammation. | 24735128 |
| Carcinogenic Chlorinated Hydrocarbon, Hepatic inflammation | Altered Intercellular Communication | CHC patients who underwent liver biopsies were subjected to Scheuer scoring analysis for scope of hepatic inflammation. | 24736528 |
| Inflammation | Altered Intercellular Communication | Innate immune responses have a critical role in regulating sight-threatening ocular surface (OcS) inflammation. | 24736562 |
| Inflammation, Atherosclerosis | Altered Intercellular Communication | Recent advances in basic science have established that inflammation plays a pivotal role in the pathogenesis of atherosclerosis. | 24737117 |
| vascular inflammations, Dental Plaque | Altered Intercellular Communication | Several literature studies experimented this new method to identify vascular inflammation, but few have effectively compared PET/CT results with plaque histological data and no studies had directly compared TBR to SUV. | 24737136 |
| Inflammation | Altered Intercellular Communication | TBR max and TBR mean values resulted higher in group A (respectively, 1.42 +- 0.32 and 1.34 +- 0.26) than in group B (respectively, 1.16 +- 0.19 and 1.03 +- 0.20) with a statistically significant differences between the two groups and carotid inflammation (respectively, p < 0.01 and p < 0.001). | 24737136 |
| Disease, Polyarteritis Nodosa, Inflammation, Vascular Diseases | Altered Intercellular Communication | Adenosine deaminase 2 (ADA2) deficiency due to CECR1 mutations is a recently defined disorder that involves systemic inflammation and vasculopathy often associated with polyarteritis nodosa. | 24737293 |
| Inflammation, Chronic disease | Altered Intercellular Communication | Many chronic diseases are characterised by low-grade systemic inflammation. | 24737458 |
| Inflammation | Altered Intercellular Communication | In vitro culture and animal experiments suggest oestrogens are anti-inflammatory and might thereby protect against low-grade systemic inflammation. | 24737458 |
| Inflammation, senile, Benign prostatic hypertrophy, prostatitis | Altered Intercellular Communication | In the clinical settings and in animal experiments the research was conducted on effectiveness and safety of treatment the benign prostatic hyperplasia, chronic prostatitis in the stage of active inflammation in elderly and senile patients. | 24738261 |
| Inflammation, Genus: Leishmania, Leishmaniasis | Altered Intercellular Communication | Cutaneous leishmaniasis was diagnosed by smear and histology, showing large amounts of leishmania amastigotes in subepidermal histiocytes and extensive lymphocyte and plasma cell inflammation. | 24739742 |
| Inflammation, Nonmyeloablative Allogeneic Hematopoietic Stem Cell Transplantation | Altered Intercellular Communication | AB103 is a safe, promising new agent for modulation of inflammation after NSTI. | 24740134 |
| ovarian neoplasm, Inflammation | Altered Intercellular Communication | Survival in epithelial ovarian cancer (EOC) is influenced by the host immune response, yet the key genetic determinants of inflammation and immunity that affect prognosis are not known. | 24740199 |
| Inflammation, Histology | Altered Intercellular Communication | These associations highlight the potential importance of genes associated with host inflammation and immunity in modulating clinical outcomes in distinct EOC histologies. | 24740199 |
| Inflammation, Diverticulitis | Altered Intercellular Communication | Diverticulosis can lead to diverticulitis, a colon condition involving inflammation and other complications. | 24740401 |
| Inflammation, Fibromyalgia | Altered Intercellular Communication | The finding of this pattern of altered cytokine milieu not only supports the role of inflammation in FMS but also may lead to more definitive diagnostic tools for clinicians treating FMS. | 24741634 |
| Inflammation, Chronic Obstructive Airway Disease, Lung diseases | Altered Intercellular Communication | Chronic obstructive pulmonary disease is a lung disorder characterized by chronic inflammation of the respiratory tract after exposure to pollutants, causing the obstruction of small respiratory tracts and the destruction of lung parenchyma. | 24741796 |
| Inflammation, Thrombosis | Altered Intercellular Communication | Evidence suggests that platelets play a significant role in inflammation in addition to their role in thrombosis. | 24743560 |
| ARCN1 gene, Inflammation | Altered Intercellular Communication | Systemic inflammation is linked to poor short and long term outcomes in COPD. | 24743560 |
| glycation, Inflammation | Altered Intercellular Communication | Dietary intake of advanced glycation end products did not affect endothelial function and inflammation in healthy adults in a randomized controlled trial. | 24744309 |
| Deficiency of micronutrients, Inflammation | Altered Intercellular Communication | Micronutrient deficiencies are common in 6- to 8-year-old children of rural Nepal, with prevalence estimates modestly affected by inflammation. | 24744314 |
| Inflammation, Chronic Kidney Diseases | Altered Intercellular Communication | The association between inflammation and CKD has been explored in several studies. | 24745010 |
| Inflammation, Isthmic spondylolisthesis, Abnormality of the vasculature | Altered Intercellular Communication | Based on previous reports about secondary spinal DAVFs, the abnormal vascular communication likely developed secondary to the microtrauma and inflammation on the left L-4 nerve root sleeve, which was attributable to the isthmic spondylolisthesis. | 24745354 |
| Inflammation, Traumatic injury | Altered Intercellular Communication | It is important to bear in mind that a spinal DAVF may develop as a consequence of any sort of trauma or inflammation involving nerve roots. | 24745354 |
| Inflammation, Depressed mood, Sleep disturbances | Altered Intercellular Communication | Inflammation, sleep disturbances, and depressed mood among community-dwelling older men. | 24745777 |
| Inflammation, Sleep disturbances | Altered Intercellular Communication | We sought to determine if sleep disturbances explain a portion of the putative inflammation - depression association among older adults. | 24745777 |
| Depression, CTCAE | Altered Intercellular Communication | We also tested whether inflammation-probable depression associations were moderated by age. | 24745777 |
| Inflammation, Hostility | Altered Intercellular Communication | The relation between hostility and concurrent levels of inflammation is sex, age, and measure dependent. | 24745780 |
| Inflammation, Hostility | Altered Intercellular Communication | Hostility may be associated with greater systemic inflammation. | 24745780 |
| Inflammation, Coronary Artery Disease, Hostility | Altered Intercellular Communication | Main and interactive effects of hostility with sex and/or age were evaluated on markers of inflammation, independently of traditional risk factors for coronary artery disease. | 24745780 |
| AVP gene, Panhypopituitarism | Altered Intercellular Communication | Further hormonal work-up revealed panhypopituitarism but no diabetes insipidus. | 24746111 |
| Inflammation, Diabetes Mellitus, Cardiovascular Diseases | Altered Intercellular Communication | Insulin resistance (IR) and inflammation have been implicated in pathogenesis of diabetes and cardiovascular disease. | 24746438 |
| Inflammation, Coronary Artery Disease, Diabetes Mellitus | Altered Intercellular Communication | Hence, we studied the association of dietary factors with IR and inflammation in known patients with diabetes mellitus and coronary artery disease with the hypothesis that carbohydrate and fat will be positively; and protein, fiber and mineral will be negatively associated with IR and inflammatory markers. | 24746438 |
| Hereditary Autoinflammatory Diseases, Fever, CTCAE, Cervical lymphadenitis, Aphthous Stomatitis, Pharyngitis | Altered Intercellular Communication | The periodic fever, aphthous stomatitis, pharyngitis and cervical adenitis (PFAPA) syndrome is an autoinflammatory disease characterized by regularly recurrent fever episodes due to seemingly unprovoked inflammation. | 24746456 |
| Inflammation, Ophthalmoplegia, Myositis, CTCAE 5.0, Pain | Altered Intercellular Communication | Ocular myositis is a rare disorder characterized by inflammation of single or multiple extra-ocular eye muscles presenting with painful diplopia and/or ophthalmoplegia. | 24746476 |
| Inflammation, Fibrosis Assessment | Altered Intercellular Communication | Nitric oxide (NO), mainly synthesized by inducible nitric oxide synthase (NOS2) in pathological conditions, plays an important role in cytotoxicity, inflammation and fibrosis. | 24746566 |
| Inflammation, Cachexia, Neoplasms | Altered Intercellular Communication | Inflammation is an important feature of the malignant phenotype and promotes angiogenesis, tumour invasiveness, metastases, and cachexia. | 24746841 |
| Acute Coronary Syndrome, GDC AJCC Clinical Stage Terminology, Rupture, Plaque, Atherosclerotic | Altered Intercellular Communication | Acute coronary syndrome (ACS) is caused by destabilization and rupture of atherosclerotic plaque in the coronary artery via mechanisms affecting leukocyte signaling, rolling, adhesion, extravasation and inflammation-promoting factors. | 24748045 |
| Inflammation, Liver carcinoma, FAM126A gene | Altered Intercellular Communication | Serum g-glutamyltranspeptidase (GGT) level, which is often elevated in hepatocellular carcinoma (HCC), has now been found to be an oxidative stress marker which correlates with inflammation in the extracellular hepatic microenvironment. | 24748164 |
| Pulmonary Emphysema, Inflammation, Respiratory Tract Infections, Osteoporosis | Altered Intercellular Communication | In observational studies vitamin D deficiency has been associated with decreased pulmonary function, presence of emphysema and osteoporosis, upper respiratory tract infections, and systemic inflammation. | 24748443 |
| Degenerative polyarthritis, Inflammation | Altered Intercellular Communication | Soluble TNF receptors are produced at sites of inflammation and are inversely associated with self-reported symptoms (WOMAC) in knee osteoarthritis. | 24748490 |
| Weight decreased, Bronchial Hyperreactivity, Pneumonitis, Airway Obstruction | Altered Intercellular Communication | hMPV-infected mice lacking AMs exhibited improved disease in terms of body weight loss, lung inflammation, airway obstruction, and hyperresponsiveness compared with AM-competent mice. | 24749674 |
| Communicable Diseases, Inflammation | Altered Intercellular Communication | In contrast, AM depletion in the context of RSV infection was characterized by an increase in viral replication, worsened disease, and inflammation, with increased airway neutrophils and inflammatory dendritic cells. | 24749674 |
| Pancreatic carcinoma | Altered Intercellular Communication | Prognostic value of systemic inflammation-based markers in advanced pancreatic cancer. | 24750233 |
| Malignant Neoplasms | Altered Intercellular Communication | The prognostic significance of various systemic inflammation-based markers has been explored in different cancers. | 24750233 |
| Inflammation, Fever, CTCAE, Acute prostatitis, Dysuria, Suprapubic pain | Altered Intercellular Communication | The present study reports the case of a 67-year-old man who was admitted to our transplant unit 3.5 months post transplantation with fever, dysuria, suprapubic pain, symptoms and signs of acute prostatitis, and elevated markers of inflammation and prostate-specific antigen. | 24750300 |
| Inflammation, Chronic Obstructive Airway Disease | Altered Intercellular Communication | Systemic inflammation in patients with chronic obstructive pulmonary disease undergoing percutaneous coronary intervention. | 24750361 |
| ARCN1 gene, Inflammation, Chronic Obstructive Airway Disease, Coronary Artery Disease | Altered Intercellular Communication | Systemic inflammation plays an important role in both chronic obstructive pulmonary disease (COPD) and coronary artery disease (CAD). | 24750361 |
| Inflammation, Kidney Diseases | Altered Intercellular Communication | Protein-bound uremic toxins, inflammation and oxidative stress: a cross-sectional study in stage 3-4 chronic kidney disease. | 24751327 |
| Inflammation, Chronic Kidney Diseases | Altered Intercellular Communication | We undertook this study to investigate the associations between IS and PCS and both inflammation and oxidative stress in the chronic kidney disease (CKD) population. | 24751327 |
| Inflammation, Toxic effect | Altered Intercellular Communication | Inflammation and oxidative stress may contribute to the nephro- and cardiovascular toxicities of IS and PCS. | 24751327 |
| Non-necrotizing granulomatous inflammation | Altered Intercellular Communication | A CT-guided biopsy of the L1-L2 vertebral bodies showed non-caseating granulomatous inflammation. | 24751456 |
| Inflammation, Cardiovascular Diseases | Altered Intercellular Communication | Systemic inflammation has been implicated as an early marker for subclinical cardiovascular disease; however, findings have been inconsistent in the African-American population. | 24751480 |
| Inflammation, Periodontitis | Altered Intercellular Communication | Compared with healthy controls, the score of gingival tissue inflammation was significantly increased in the chronic moderate periodontitis (P=0.013) and chronic severe periodontitis (P<0.0001), and the densities (cells/mm(2)) of tryptase-TIM-3 double-positive MCs were significantly increased in both the chronic moderate (P=0.011) and severe periodontitis groups (P<0.0001). | 24751779 |
| Inflammation, Periodontitis | Altered Intercellular Communication | However, compared with the chronic moderate periodontitis group, both the score of gingival tissue inflammation (P=0.012) and the density of tryptase-TIM-3 double-positive MCs (P=0.011) in gingival tissue were significantly increased in the severe periodontitis groups. | 24751779 |
| Periodontitis | Altered Intercellular Communication | Significantly increased number of tryptase-TIM-3 double-positive MCs had the similar tendency as the severity of periodontitis inflammation in human chronic periodontitis. | 24751779 |
| Hypersensitivity | Altered Intercellular Communication | Mast cells (MCs) are implicated in the pathogenesis of allergic reactions and inflammatory conditions through the release of inflammatory mediators. | 24751779 |
| Inflammation, Fibrosis Assessment, Swelling, Thyroid associated opthalmopathies | Altered Intercellular Communication | Graves' orbitopathy (GO) is a disfiguring and sometimes blinding disease, characterised by inflammation and swelling of orbital tissues, with fibrosis and adipogenesis being predominant features. | 24751986 |
| Inflammation, Hand | Altered Intercellular Communication | Alterations in the CSF metabolome of HIV patients on ART suggest that persistent inflammation, glial responses, glutamate neurotoxicity, and altered brain waste disposal systems contribute to mechanisms involved in HAND that may be augmented with aging. | 24752083 |
| TNF protein, human, Inflammation, Depression, CTCAE | Altered Intercellular Communication | In addition, vascular risk factors, including high body mass index level, presence of inflammation markers (e.g., CRP, TNF-a, Hs-CRP, and IL-6), and lack of physical activity, were associated with depression. | 24752391 |
| Tissue damage, Acute inflammation | Altered Intercellular Communication | Deregulated and hyperactive inflammation contributes to tissue damage and parasite persistence. | 24752514 |
| Primary malignant neoplasm, Hepatic inflammation, FAM126A gene | Altered Intercellular Communication | These findings broaden the knowledge of hepatic inflammation and cancer initiation/progression, and also provide novel prognostic biomarkers and therapeutic targets for HCC. | 24752868 |
| Communicable Diseases, Inflammation | Altered Intercellular Communication | Discogenic back pain can be initiated by tissue disruption, and amplified by inflammation and infection. | 24753325 |
| Inflammation, Metabolic Syndrome X | Altered Intercellular Communication | Polymorphism at the TNF-alpha gene interacts with Mediterranean diet to influence triglyceride metabolism and inflammation status in metabolic syndrome patients: From the CORDIOPREV clinical trial. | 24753491 |
| TG gene, Tumor necrosis, Inflammation, ETV3 wt Allele | Altered Intercellular Communication | These results suggest that the rs1800629 at the tumor necrosis factor alpha gene interacts with MedDiet to influence TG metabolism and inflammation status in MetS subjects. | 24753491 |
| Seizures, Inflammation | Altered Intercellular Communication | We hypothesized that TBI-induced inflammation likely contributes to seizure development. | 24754437 |
| Inflammation, Obesity | Altered Intercellular Communication | This corroborates the concept that complement contributes to the low-grade inflammation associated with obesity. | 24754458 |
| Inflammation, Impaired cognition, Osteochondritis Dissecans | Altered Intercellular Communication | Accumulating evidence has indicated that inflammation may act as a potential mechanism underlying post-operative cognitive dysfunction (POCD). | 24754551 |
| Inflammation, Heart failure | Altered Intercellular Communication | Various adipokines are reported to be associated with the development of heart failure (HF) through insulin resistance and chronic inflammation. | 24755035 |
| Inflammation | Altered Intercellular Communication | Long-term exposures to particulate matter air pollution (PM2.5 and PM10) and high traffic load have been associated with markers of systemic inflammation. | 24755038 |
| Inflammation, Atherosclerosis | Altered Intercellular Communication | Our previous in-vivo and in-vitro studies demonstrated that inflammation accelerated the progression of atherosclerosis via the dysregulation of the low-density lipoprotein receptor (LDLr) pathway. | 24755105 |
| Inflammation | Altered Intercellular Communication | Confocal microscopy showed that inflammation enhanced the translocation of SCAP escorting SREBP-2 from the endoplasmic reticulum to the Golgi, thereby activating LDLr gene transcription. | 24755105 |
| Kidney Failure, Chronic, Inflammation | Altered Intercellular Communication | Inflammation contributed to foam cell formation in the radial arteries of ESRD patients via the dysregulation of the LDLr pathway, which could be modulated by the activation of the mTOR pathway. | 24755105 |
| Inflammation, HIV, physiopathological | Altered Intercellular Communication | While inflammation predicts mortality in treated human immunodeficiency virus (HIV) infection, the prognostic significance of gut barrier dysfunction and phenotypic T-cell markers remains unclear. | 24755434 |
| Inflammation, Acquired Immunodeficiency Syndrome, HIV Infections | Altered Intercellular Communication | Gut epithelial barrier dysfunction, innate immune activation, inflammation, and coagulation-but not T-cell activation, senescence, and exhaustion-independently predict mortality in individuals with treated HIV infection with a history of AIDS and are viable targets for interventions. | 24755434 |
| Specimen Source Codes - Abscess | Altered Intercellular Communication | Autopsy revealed adrenal gland chronic inflammation and abscess. | 24755510 |
| Non-Small Cell Lung Carcinoma | Altered Intercellular Communication | Inflammation-related genetic variations and survival in patients with advanced non-small cell lung cancer receiving first-line chemotherapy. | 24755914 |
| Inflammation | Altered Intercellular Communication | We systematically investigated genetic variants within inflammation pathways as potential prognostic markers for advanced-stage NSCLC patients treated with first-line chemotherapy. | 24755914 |
| Inflammation | Altered Intercellular Communication | However, this signal is counteracted in noncirrhotic liver tissue (showing various levels of inflammation) by high availability of interleukin-12 and IFN-g, ultimately leading to complete, full Th1-like Treg differentiation. | 24756990 |
| Inflammation, Rheumatoid Arthritis, Rheumatoid Factor | Altered Intercellular Communication | Rheumatoid factor as a potentiator of anti-citrullinated protein antibody-mediated inflammation in rheumatoid arthritis. | 24757134 |
| Refractory anemias, Inflammation | Altered Intercellular Communication | The combined presence of ACPAs and IgM-RF mediates increased proinflammatory cytokine production in vitro and is associated with increased systemic inflammation and disease activity in RA. | 24757134 |
| Inflammation | Altered Intercellular Communication | The inflammation status of the synovial membrane was characterized according to macroscopic criteria and classified as normal/reactive or inflamed. | 24757147 |
| Inflammation, Disorder of tendon | Altered Intercellular Communication | The pathogenetic mechanisms underlying tendinopathy remain unclear, with much debate as to whether inflammation or degradation has the prominent role. | 24757284 |
| Inflammation, Cholestasis, pathologic cytolysis | Altered Intercellular Communication | The changes of standard indicators of cytolysis, cholestasis and protein metabolism were on average moderate in group with reliable increase of protein concentration of acute phase of inflammation. | 24757856 |
| Airway structure | Altered Intercellular Communication | Dendritic cells from aged subjects contribute to chronic airway inflammation by activating bronchial epithelial cells under steady state. | 24759206 |
| Airway structure, Respiration Disorders | Altered Intercellular Communication | Thus, age-associated alterations in DC-epithelial interactions contribute to chronic airway inflammation in the elderly, increasing their susceptibility to respiratory diseases. | 24759206 |
| Inflammation, Impaired cognition | Altered Intercellular Communication | Studies have suggested CD8 lymphocytes may be a possible marker for inflammation, which is believed to be a contributing factor to neurocognitive impairment. | 24759562 |
| Reproductive tract infection, Inflammation | Altered Intercellular Communication | Mycoplasma genitalium infection is associated with microscopic signs of cervical inflammation in liquid cytology specimens. | 24759719 |
| Inflammation, Uterine Cervicitis, Etiology aspects, Sexually Transmitted Diseases | Altered Intercellular Communication | In this study, we comparatively assessed inflammation among the common infectious etiologies of cervicitis and assessed the potential value of liquid cytology specimens for predicting STIs. | 24759719 |
| Primary malignant neoplasm, Liver carcinoma, FAM126A gene | Altered Intercellular Communication | Hepatocellular carcinoma (HCC) is a classical example of inflammation-linked cancer and is characterized by hypervascularity suggesting rich angiogenesis. | 24759835 |
| Inflammation, Neoplasms | Altered Intercellular Communication | Nearly all tumors arose in regions of chronic inflammation and caused luminal narrowing with pre-stenotic dilatation. | 24760323 |
| Inflammation | Altered Intercellular Communication | Suppression of Alzheimer-associated inflammation by microglial prostaglandin-E2 EP4 receptor signaling. | 24760848 |
| Inflammation, Ulcer | Altered Intercellular Communication | Tissue remission was defined by the absence of ulcer at endoscopy and/or absence of signs of acute inflammation at MRI. | 24761690 |
| Inflammatory Bowel Diseases, Inflammation, Venous Thromboembolism, Abnormality of coagulation | Altered Intercellular Communication | Literature on incidence of venous thromboembolism in inflammatory bowel disease (IBD) is reviewed as well as the possible pathogenetic mechanisms of this 'hypercoagulable state': role of acquired risk factors, inflammation, coagulation abnormalities and platelets. | 24761694 |
| ARCN1 gene, Pneumonitis | Altered Intercellular Communication | IL-32 was involved in cigarette smoke-induced pulmonary inflammation in COPD. | 24761997 |
| ARCN1 gene, Pneumonitis | Altered Intercellular Communication | This study revealed the critical role of IL-32 in pulmonary inflammation of COPD and smoker-associated diseases. | 24761997 |
| Inflammation | Altered Intercellular Communication | We hypothesized that genetically increased body mass index (BMI) is associated with telomere length shortening and that low-grade inflammation might contribute through elevated C-reactive protein. | 24762112 |
| Colorectal Carcinoma | Altered Intercellular Communication | Polymorphisms of inflammation-related genes and colorectal cancer risk: a population-based case-control study in China. | 24762198 |
| Inflammation, Colorectal Carcinoma | Altered Intercellular Communication | The previous studies found that chronic inflammation related to an increased risk of colorectal cancer (CRC). | 24762198 |
| Malignant tumor of colon, Primary malignant neoplasm, Colorectal Carcinoma | Altered Intercellular Communication | Multivariate unconditional logistic regression was used to analyse the association of nine SNPs in inflammation-related genes with the risk of CRC, colon cancer and rectal cancer, respectively. | 24762198 |
| Colorectal Carcinoma | Altered Intercellular Communication | However, there is no interaction between inflammation-related genes on CRC risk. | 24762198 |
| Inflammation, Malignant Neoplasms | Altered Intercellular Communication | Both inflammation and mitochondrial DNA (mtDNA) mutation are thought to play a role in the many human cancers. | 24762507 |
| Gastritis | Altered Intercellular Communication | Gastric mucosa inflammation was significantly milder in the T group than that in the P group one year after Hp eradication and this persisted for 10 years. | 24762588 |
| Inflammatory disease of mucous membrane, Gastritis, Atrophic | Altered Intercellular Communication | Hp eradication may significantly diminish and help halt progression of gastric mucosal inflammation and delay the development of IM and atrophy gastritis. | 24762588 |
| Inflammation, Sore to touch | Altered Intercellular Communication | On examination, inflammation was noted over a bony mass associated with tenderness to palpation of the affected area. | 24762849 |
| Keratitis, Ulceration, CTCAE | Altered Intercellular Communication | Corneal inflammation and ulceration could not be controlled after 2 weeks of topical antiinflammation treatment. | 24763125 |
| Inflammation, Damage | Altered Intercellular Communication | CXCL13 levels were analysed in relation to cellular, molecular and clinical features of inflammation, lymphocyte activation and joint damage. | 24764267 |
| Inflammation | Altered Intercellular Communication | In patients with early disease (<12 months duration), CXCL13 expression correlated significantly with synovial markers of local disease activity and systemic inflammation. | 24764267 |
| Inflammation | Altered Intercellular Communication | Accordingly, synovial CXCL13 and the local receptor activator of nuclear factor kB ligand (RANKL)/osteoprotegerin (OPG) ratio significantly co-varied (r = 0.52, P < 0.01), independent of the level of local inflammation. | 24764267 |
| Inflammation, Disease | Altered Intercellular Communication | Synovial CXCL13 appears to be a marker of a more severe pattern of RA disease, characterized by increased lymphocyte activation and bone remodelling beyond the level of conventional markers of inflammation. | 24764267 |
| Refractory anemias, Inflammation, Rheumatoid Arthritis | Altered Intercellular Communication | Here, we examined the potential contributions of synovial Btk expression and activation to inflammation in rheumatoid arthritis (RA). | 24764451 |
| Inflammation, Metabolic Diseases, Necrosis, Communicable Diseases, Fibrosis Assessment, Fatty degeneration, Autoimmune Chronic Hepatitis, Celiac Disease | Altered Intercellular Communication | The disease was diagnosed if liver biopsy revealed steatosis, inflammation, ballooned hepatocytes, Mallory hyaline, or focal necrosis, varying degrees of fibrosis in the absence of clinical, serological, or histological findings of infectious liver diseases, autoimmune hepatitis, metabolic liver diseases, or celiac disease. | 24764670 |
| Inflammation, Thrombosis, Cyclophosphamide/Vincristine/Dacarbazine Regimen, Cardiovascular Diseases | Altered Intercellular Communication | Cardiovascular disease (CVD) results from a combination of abnormalities in lipoprotein metabolism, oxidative stress, chronic inflammation, and susceptibility to thrombosis. | 24766787 |
| Inflammation, Heart failure, Coronary Artery Disease | Altered Intercellular Communication | Inflammation and future risk of symptomatic heart failure in patients with stable coronary artery disease. | 24766981 |
| Inflammation, Thyroid associated opthalmopathies, Diplopia, Disorder of the optic nerve, Muscle of orbit, Unspecified visual loss, Exophthalmos | Altered Intercellular Communication | The results were compared with clinical severity scores (clinical activity score, VISA (vision loss (optic neuropathy); inflammation; strabismus/motility; appearance/exposure) classification, modified NOSPECS (no signs or symptoms; only signs; soft tissue; proptosis; extraocular muscle; cornea; sight loss) score, Gorman diplopia scale, and European Group of Graves' Orbitopathy Classification). | 24767223 |
| Inflammation, Strabismus | Altered Intercellular Communication | Clinical scores indicating inflammation and strabismus in patients with TED were positively correlated with overall and visual function-related QOL (Spearman coefficient 0.21-0.38, p < 0.05). | 24767223 |
| Dysmotility, Inflammation | Altered Intercellular Communication | In multivariate analysis, age, soft-tissue inflammation, motility disorder of modified NOSPECS, and motility disorder of VISA classification had positive correlation with overall and function-related QOL. | 24767223 |
| Inflammation, Exophthalmos | Altered Intercellular Communication | Sex, soft-tissue inflammation, proptosis of modified NOSPECS, and appearance of VISA classification had correlation with appearance-related QOL. | 24767223 |
| Inflammation, Fibrosis Assessment, Cholestasis | Altered Intercellular Communication | Histopathology of a needle graft biopsy performed on POD 28 revealed FCH with extensive portal fibrosis accompanied by mild inflammation, hepatocyte ballooning, and ductular proliferation with cholestasis. | 24767401 |
| Respiratory Distress Syndrome, Adult, Inflammation, Lung Injury, Respiratory Distress Syndrome, Newborn | Altered Intercellular Communication | The acute respiratory distress syndrome (ARDS) is a common, devastating complication of critical illness that is characterized by pulmonary injury and inflammation. | 24767549 |
| Inflammation | Altered Intercellular Communication | Increased metabolism in plaques, measured as FDG uptake in PET/CT examination, has been associated with markers of inflammation in histological samples. | 24767629 |
| Inflammation, Hypoxia, Dental Plaque | Altered Intercellular Communication | This indicates an association between vascularization and inflammation and/or hypoxia, supporting the use of CEUS as a non-invasive method to detect plaque vulnerability. | 24767629 |
| Cholesterolosis, Cholecystitis, Hyperplasia, Xanthogranulomatous inflammation | Altered Intercellular Communication | Histologic findings included chronic (91.1%) or acute (15.4%) cholecystitis, cholesterosis (10.9%), adenomyomatous hyperplasia (2.1%), xanthogranulomatous inflammation (2.02%), and "porcelain" gallbladder (0.2%). | 24768494 |
| Inflammation, Pancreatitis | Altered Intercellular Communication | Acute pancreatitis as a result of the hookworms migrating into the ampulla of Vater with chronic inflammation was a very rare complication. | 24768664 |
| Inflammation, Liver damage, Chronic disease | Altered Intercellular Communication | Th2-type inflammation under conditions of pre-existing chronic disease is associated with liver damage in patients with avian influenza H7N9 virus. | 24769417 |
| Inflammation, Chronic disease | Altered Intercellular Communication | Taken together, our results suggest that Th2-type inflammation in H7N9-infected patients with pre-existing chronic diseases likely contributes to the pathogenesis of H7N9 infection and is linked to poor clinical outcomes. | 24769417 |
| PROS1 gene, Psoriasis | Altered Intercellular Communication | The initial telomere size from PsA patients was higher than those with cutaneous psoriasis only (n = 53), possibly due to the inflammatory condition. | 24769426 |
| Inflammation, Atherosclerosis | Altered Intercellular Communication | Recent studies have suggested that proprotein convertase subtilisin/kexin type 9 (PCSK9) is associated with atherosclerosis and plays a potential role in inflammation. | 24769476 |
| Inflammation | Altered Intercellular Communication | These data demonstrate that the plasma PCSK9 levels are independently associated with the WBCC and its subsets, suggesting a potential interaction between PCSK9 and chronic inflammation in patients with CAD. | 24769476 |
| Cystic degeneration, Cardiovascular Diseases | Altered Intercellular Communication | Ascending aortic dilatation (AAD) is a common cardiovascular disease and is associated with aortic wall inflammation and cystic degeneration. | 24769814 |
| Inflammation | Altered Intercellular Communication | In patients with AAD, RDW and hs-CRP levels are increased, which may indicate the role of inflammation in the pathogenesis of AAD. | 24769814 |
| Inflammation, Cardiovascular Diseases | Altered Intercellular Communication | Inflammation and prolonged QT time: results from the Cardiovascular Disease, Living and Ageing in Halle (CARLA) study. | 24770373 |
| Uveomeningoencephalitic Syndrome, Blurred vision, Headache, Inflammation | Altered Intercellular Communication | VKH presents as blurring of vision and eye inflammation, severe headaches, and meningismis. | 24770410 |
| Inflammation, Observation Method - Coagulation, Pulmonary Hypertension | Altered Intercellular Communication | Fibrinogen has a crucial role in both inflammation and coagulation, two processes pivotal for the pathogenesis of pulmonary hypertension. | 24770447 |
| Seizures, Inflammation, Subarachnoid Hemorrhage | Altered Intercellular Communication | Nonconvulsive seizures in subarachnoid hemorrhage link inflammation and outcome. | 24771589 |
| Seizures, Brain Injuries, Inflammation Mediators | Altered Intercellular Communication | Proinflammatory states are common after many brain injuries, and inflammation-mediated changes in blood-brain barrier permeability have been experimentally linked to seizures. | 24771589 |
| ACSM3 gene, Inflammation | Altered Intercellular Communication | In-hospital NCSz were independently associated with a proinflammatory state following SAH as reflected in clinical symptoms and serum biomarkers of inflammation. | 24771589 |
| ACSM3 gene, Inflammation | Altered Intercellular Communication | Our findings suggest that inflammation following SAH is associated with poor outcome and that this effect is at least in part mediated through in-hospital NCSz. | 24771589 |
| Atrial Fibrillation, Inflammation, Atrial Fibrillation by ECG Finding | Altered Intercellular Communication | Atrial fibrillation (AF) is burdened by enhanced systemic inflammation and platelet activation, as documented by increased blood levels of soluble CD40L (sCD40L). | 24771985 |
| Inflammation, Thrombosis | Altered Intercellular Communication | Inflammation has been associated with insulin resistance, type 2 diabetes mellitus (T2DM), and atherothrombosis. | 24772446 |
| Inflammation, Cardiovascular Diseases | Altered Intercellular Communication | Inflammation and prothrombotic state are present in people with T2DM lacking cardiovascular disease. | 24772446 |
| Inflammatory, Inflammation | Altered Intercellular Communication | Patients with pSS were classified accordingly with the grade of inflammatory lesions as I = low-grade (low focus score of 1 or 2), II = intermediate-grade (focus score of 3-6) and III = extensive inflammation in the MSG (high focus score of 12). | 24772480 |
| Inflammation, Primary malignant neoplasm, Anemia | Altered Intercellular Communication | Often due to a severe somatic condition of the patient, the presence of perifocal inflammation, anemia, age, it is not possible to perform neoadjuvant chemoradiotherapy for rectal cancer. | 24772619 |
| Inflammation, Leukocytosis, Fever, CTCAE, Ulcerative Colitis, Abdominal Pain | Altered Intercellular Communication | With increasing of clinical disease activity in patients with UC as well as CD was marked a significantly increased content of calprotectin in stool samples, which was accompanied by increase of indicators of inflammation acute phase: rising RRF, leukocytosis, an increase of frequency of stool with blood and mucus, fever and abdominal pain. | 24772858 |
| Inflammation, Transfusion-Related Acute Lung Injury | Altered Intercellular Communication | Patients with transfusion-related acute lung injury had evidence of more systemic inflammation with increases in circulating neutrophils and a decrease in platelets compared with controls. | 24776608 |
| Inflammation, Fatty infiltration | Altered Intercellular Communication | At univariate analysis, the IL28B CC genotype was associated with severe portal inflammation in HCV-1 patients (CC vs. 86% vs. 63%, p = 0.005), severe lobular inflammation in HCV-2 patients (CC vs. 44% vs. 23%, p = 0.03), and less fatty infiltration in HCV-1 patients (CC vs. 72% vs. 51%, p = 0.02). | 24776764 |
| Inflammation | Altered Intercellular Communication | At multivariate analysis, the genotype CC remained associated with severe portal inflammation in HCV-1, only (Odds Ratio (OR): 95% Confidence Interval (CI): 3.24 (1.23-8.51)). | 24776764 |
| Inflammation, Hepatitis C | Altered Intercellular Communication | IL28B genotype is associated with the histological features of chronic hepatitis C in a HCV genotype dependent manner, with CC genotype being independently associated with severe portal inflammation. | 24776764 |
| Communicable Diseases, Inflammation, Unspecified visual loss | Altered Intercellular Communication | Specifically, cerebrospinal fluid leak, visual loss, infection, or unanticipated inflammation were not encountered. | 24777260 |
| cervical cancer, Acute and chronic inflammation | Altered Intercellular Communication | No expression was detected in cervical cancer and chronic cervical inflammation. | 24777814 |
| Inflammation, Fibrosis Assessment, Calcified (qualifier) | Altered Intercellular Communication | Histology revealed chronic and acute inflammation, thick-walled occluded vessels, fibrosis and characteristic bi-refringent lamellar deposits of globotriaosylceramide and calcifications. | 24778057 |
| Inflammation, Asthma, Endothelial dysfunction, Coronary heart disease | Altered Intercellular Communication | [The features of risk factors, systemic inflammation, and endothelial dysfunction in patients with asthma concurrent with coronary heart disease]. | 24779068 |
| Inflammation, Coronary heart disease, Endothelial dysfunction, Choline Dehydrogenase, Mitochondrial, Asthma | Altered Intercellular Communication | To identify risk factors (RFs), to evaluate the impact of systemic inflammation and endothelial dysfunction on the development of asthma concurrent with coronary heart disease (CHD), and to determine the degree of control of the disease. | 24779068 |
| Inflammation, Diabetes Mellitus, Non-Insulin-Dependent | Altered Intercellular Communication | Advice to follow a low-carbohydrate diet has a favourable impact on low-grade inflammation in type 2 diabetes compared with advice to follow a low-fat diet. | 24779961 |
| Inflammation, Diabetes Mellitus, Non-Insulin-Dependent | Altered Intercellular Communication | Inflammation may play an important role in type 2 diabetes. | 24779961 |
| Inflammation, Atherosclerosis | Altered Intercellular Communication | Atherosclerosis is an aging-related disease, the pathogenesis of which involves chronic inflammation and increased oxidative stress. | 24780409 |
| Myocarditis | Altered Intercellular Communication | In the remaining cases, PVB was considered to be a bystander with no or limited association to myocardial inflammation. | 24781135 |
| Communicable Diseases, Myocarditis | Altered Intercellular Communication | The detection of PVB in myocardial autopsy samples most likely represents a persistent infection with no or limited association with myocardial inflammation. | 24781135 |
| Myocarditis | Altered Intercellular Communication | The forensic investigation of myocardial inflammation demands a thorough examination, including special attention to non-viral causes and requires a multidisciplinary approach. | 24781135 |
| Myocarditis | Altered Intercellular Communication | In 28 patients, EMB revealed no myocardial inflammation (NM). | 24781421 |
| Inflammation, Ulcerative Colitis | Altered Intercellular Communication | Ulcerative colitis (UC) is a chronic inflammation of the large intestine. | 24781989 |
| Rheumatoid Arthritis, Inflammation | Altered Intercellular Communication | Antibodies to IgG4 hinge can be found in rheumatoid arthritis patients during all stages of disease and may exacerbate chronic antibody-mediated inflammation. | 24782178 |
| Refractory anemias, Rheumatoid Arthritis, Inflammation | Altered Intercellular Communication | In rheumatoid arthritis (RA), autoantibodies such as anti-citrullinated protein antibodies (ACPAs) develop in response to neoepitopes that are formed under conditions of chronic inflammation. | 24782178 |
| Inflammation | Altered Intercellular Communication | Since a significant proportion of ACPAs can be of the IgG4 subclass, the formation of anti-IgG4 hinge antibodies may represent one mechanism of ACPA-mediated inflammation. | 24782178 |
| Rheumatoid Arthritis, Inflammation, Pain Distress Question, Fatigue | Altered Intercellular Communication | Subgrouping of patients with rheumatoid arthritis based on pain, fatigue, inflammation, and psychosocial factors. | 24782222 |
| Inflammation, Central pain, Pain Distress Question, Refractory anemias, Rheumatoid Arthritis | Altered Intercellular Communication | Among patients with rheumatoid arthritis (RA), pain may be attributed to peripheral inflammation or other causes, such as central pain mechanisms. | 24782222 |
| Inflammation, Treatment/Psychosocial Effects, Pain Distress Question, Fatigue | Altered Intercellular Communication | Cluster 1 consisted of 89 individuals with low levels of inflammation, pain, fatigue, and psychosocial distress. | 24782222 |
| Inflammation, Treatment/Psychosocial Effects, Pain Distress Question, Fatigue | Altered Intercellular Communication | Cluster 2 consisted of 57 individuals with minimal inflammation but high levels of pain, fatigue, and psychosocial distress. | 24782222 |
| Inflammation, Pain Distress Question, Fatigue | Altered Intercellular Communication | Although most patients had low levels of inflammation, pain, and fatigue, 47.3% continued to report having moderate to high levels of pain and fatigue. | 24782222 |
| Inflammation, Fatigue, Dyssomnias, Pain Distress Question | Altered Intercellular Communication | Most of these patients had minimal signs of inflammation but high levels of fatigue, pain catastrophizing, and sleep disturbance, indicative of a chronic widespread pain syndrome. | 24782222 |
| Inflammation, Fibrosis Assessment | Altered Intercellular Communication | CAP was not influenced by inflammation, fibrosis or aetiology. | 24782622 |
| Parkinson Disease | Altered Intercellular Communication | Essential change in Parkinson's disease is the impaired neurotransmission in basal ganglia. | 24783912 |
| Inflammation, IL13 gene | Altered Intercellular Communication | Allergic rhinitis is inflammation of the nasal mucosa following exposure to allergens. | 24784773 |
| Inflammation, Primary malignant neoplasm | Altered Intercellular Communication | Social network ties and inflammation in U.S. adults with cancer. | 24784985 |
| Inflammation, Loss of facial adipose tissue, Sarcopenia, Anorexia | Altered Intercellular Communication | In some patients, inflammation induces anorexia and fat loss in combination with sarcopenia. | 24785098 |
| Inflammation, Sarcopenia | Altered Intercellular Communication | In others, appetite is maintained, despite activation of systemic inflammation, leading to sarcopenia with normal or increased BMI. | 24785098 |
| Inflammation, Cardiovascular Diseases | Altered Intercellular Communication | The high prevalence of cardiovascular diseases and chronic inflammation remains a major cause of morbidity and mortality in haemodialysed patients. | 24785111 |
| ARCN1 gene | Altered Intercellular Communication | A possible link between increased metabolic activity of fat tissue and aortic wall inflammation in subjects with COPD. | 24785152 |
| ARCN1 gene, Inflammation, Cardiovascular system | Altered Intercellular Communication | Fat tissue, and particularly visceral fat, is known to play a role in low grade systemic inflammation in COPD, and is likely to contribute to the excess cardiovascular comorbidity in COPD. | 24785152 |
| Inflammation | Altered Intercellular Communication | The degree of visceral fat metabolic activity is associated with aortic inflammation. | 24785152 |
| Acute and chronic inflammation | Altered Intercellular Communication | Studies have also demonstrated pathological changes affecting the middle-ear mucosa associated with chronic sinonasal inflammation. | 24785308 |
| Inflammation | Altered Intercellular Communication | It may be related to inflammation of the orbit or paranasal sinuses. | 24785747 |
| Inflammation | Altered Intercellular Communication | The reversal of the molecular phenotype with CsA and the associated biomarkers can serve as a reference for the successful modulation of tissue inflammation with specific immune antagonists in future studies, contributing to the understanding of the specific cytokines involved in epidermal pathology. | 24786238 |
| Schizophrenia, Impaired cognition, Hyperprolinemia, Schizoaffective Disorder | Altered Intercellular Communication | l-Proline is a neuromodulator at glutamatergic synapses, and peripheral hyperprolinemia has been associated with decreased IQ, cognitive impairment, schizoaffective disorder, and schizophrenia. | 24787057 |
| Inflammatory Bowel Diseases, Colorectal Carcinoma, Colitis | Altered Intercellular Communication | Low fecal calprotectin accurately identifies inflammatory bowel disease patients without colonic inflammation in whom colorectal cancer surveillance is most effective. | 24788218 |
| Inflammation, Atherosclerosis | Altered Intercellular Communication | Varying correlation between 18F-fluorodeoxyglucose positron emission tomography and dynamic contrast-enhanced MRI in carotid atherosclerosis: implications for plaque inflammation. | 24788973 |
| Inflammation | Altered Intercellular Communication | (18)F-fluorodeoxyglucose positron emission tomography and dynamic contrast-enhanced MRI have been proposed to quantitatively assess plaque inflammation by probing macrophages and neovessels, respectively. | 24788973 |
| Inflammation | Altered Intercellular Communication | The moderate correlation shown only in symptomatic plaques indicates the presence of acute plaque inflammation with increased metabolic activity and cytokine production by inflammatory cells. | 24788973 |
| Inflammation | Altered Intercellular Communication | These results suggest efforts of the immune system to reduce inflammation and suppress an exaggerated Th2 response. | 24789687 |
| Inflammation, Edema | Altered Intercellular Communication | The severity of edema and subcutaneous inflammation, which was confirmed using ultrasonography, was significantly influenced by gravity. | 24790031 |
| Inflammation, Fibrosis Assessment, Primary Neoplasm | Altered Intercellular Communication | After surgery, the primary tumors were assessed histopathologically for fibrosis and inflammation. | 24790431 |
| Inflammation, Colorectal Carcinoma | Altered Intercellular Communication | Cyclo-oxygenase-2 (COX-2), an inducible enzyme expressed in areas of inflammation, is a target of interest for colorectal cancer therapy. | 24791632 |
| ARCN1 gene, Inflammation, Chronic Obstructive Airway Disease, Necrosis | Altered Intercellular Communication | The interleukin (IL)-32/tumor necrosis factor (TNF) a pathway is supposed to play a key role in the amplification of the immune response in chronic obstructive pulmonary disease (COPD) inflammation. | 24791863 |
| Granulomatous inflammation, Fibrosis Assessment | Altered Intercellular Communication | A CT-guided biopsy revealed granulomatous inflammation, focal fibrosis and acid-fast bacilli consistent with Mycobacterium tuberculosis (TB). | 24792024 |
| Inflammation, Aortic Valve Insufficiency | Altered Intercellular Communication | After a detailed auscultation that unmasked a diastolic cardiac murmur, an acute severe aortic insufficiency was further confirmed by echocardiography, showing inflammation and thickening of the entire aorta wall. | 24792026 |
| Gastrointestinal inflammation | Altered Intercellular Communication | Faecal calprotectin is used as a sensitive marker for gastrointestinal mucosal inflammation. | 24793248 |
| Inflammatory Bowel Diseases, Inflammation, Impaired | Altered Intercellular Communication | The degree of motility impairment within inflammatory small bowel lesions does not significantly correlate with the extent of the lesion but with the motility measured in prelesionary, non-affected segments, suggesting an interdependent functional aspect of inflammation even in morphologically non-affected small bowel segments. | 24794863 |
| Inflammation | Altered Intercellular Communication | Soluble markers of inflammation and coagulation but not T-cell activation predict non-AIDS-defining morbid events during suppressive antiretroviral treatment. | 24795473 |
| Inflammation | Altered Intercellular Communication | Ovulation influences an increased in inflammation of epithelial ovarian cells as results of constant exposure of cells to ROS. | 24795885 |
| Neurodegenerative Disorders, Inflammation | Altered Intercellular Communication | The interaction between brain and systemic inflammation may be responsible for the neurodegenerative disease progression. | 24795890 |
| Inflammation, physiopathological, Obesity | Altered Intercellular Communication | Obesity is associated with metabolic dysfunction with sex differences and chronic, low-grade inflammation.We proposed that hepatic expression of immune complement C3 related receptors (C3aR, C5aR, and C5L2) would be associated with pre- or postmenopausal status and metabolic profile in severely obese women. | 24796007 |
| Inflammation, Chorioamnionitis | Altered Intercellular Communication | The peripheral Treg pool of preterm infants could be altered by prenatal exposure to inflammation and chorioamnionitis; however, the clinical implications of this finding are not yet understood. | 24796788 |
| Inflammation, Neoplasms | Altered Intercellular Communication | Intensity of gadolinium enhancement on MRI is useful in differentiation of intracochlear inflammation from tumor. | 24797564 |
| Inflammation, Labyrinth, Neoplasms | Altered Intercellular Communication | Intensity of gadolinium enhancement on MRI is useful in differentiation of inflammation from tumors; normalized T1 postgadolinium intensity ratio greater than 3 is strongly suggestive of intralabyrinthine tumor. | 24797564 |
| Gout | Altered Intercellular Communication | An MRI assessment of chronic synovial-based inflammation in gout and its correlation with serum urate levels. | 24797771 |
| Gout | Altered Intercellular Communication | The aim of this study was to determine the percentage of patients with inter-critical gout who have chronic synovial-based inflammation as evidenced by synovial pannus on a contrast-enhanced magnetic resonance imaging (MRI) of their most involved joint and determine if the presence and/or severity correlates with their serum urate levels. | 24797771 |
| Gout | Altered Intercellular Communication | The majority of patients with inter-critical gout have evidence of chronic synovial-based inflammation. | 24797771 |
| Inflammation | Altered Intercellular Communication | The healed phase had subtle histological features, sparse medial inflammation, marked medial attenuation, and chronic adventitial inflammation. | 24798167 |
| Inflammation, Traumatic injury, Neoplasms, Skin | Altered Intercellular Communication | Osteoma cutis encompasses a group of cutaneous ossifying disorders, more commonly secondary to trauma, inflammation or neoplasms. | 24798356 |
| Inflammatory Bowel Diseases, Inflammation, Colitis | Altered Intercellular Communication | In patients with IBD, histologically normal and inflamed colon were distinguishable with per-class accuracies of 0.83 and 0.89, respectively; histologically normal from inactive inflammation with accuracies of 0.73 and 0.89, respectively; and inactive from active colitis with accuracies of 0.87 and 0.84, respectively. | 24798637 |
| Inflammatory Bowel Diseases, Gastrointestinal inflammation | Altered Intercellular Communication | Systemic metabolic signaling in acute and chronic gastrointestinal inflammation of inflammatory bowel diseases. | 24799023 |
| Gastrointestinal inflammation | Altered Intercellular Communication | Acute and chronic intestinal inflammation stimulates innate and adaptive immune systems, thereby increasing energy demand of activated immune cells. | 24799023 |
| Gastrointestinal inflammation | Altered Intercellular Communication | We wanted to find out how systemic metabolic mediators are affected during intestinal inflammation. | 24799023 |
| Gastrointestinal inflammation, Ulcerative Colitis | Altered Intercellular Communication | Intestinal inflammation was accompanied by elevated systemic inflammatory para-meters such as IL-6 and CRP in UC and CD and, concomitantly, with elevated insulin levels and increased insulin/glucose ratio in patients with UC. | 24799023 |
| Gastrointestinal inflammation, Ulcerative Colitis | Altered Intercellular Communication | In addition, intestinal inflammation was associated with elevated levels of circulating free fatty acids in UC and CD, indicating an activation of the organism's appeal for energy-rich substrates (energy appeal reaction). | 24799023 |
| Gastrointestinal inflammation, Ulcerative Colitis | Altered Intercellular Communication | RBP-4 serum levels were also high in acute and chronic intestinal inflammation in UC and CD, which can support insulin resistance. | 24799023 |
| Inflammation | Altered Intercellular Communication | The organism's "energy appeal reaction" in response to acute and chronic inflammation provides free energy in the circulation, which is needed by inflammatory cells. | 24799023 |
| Inflammation | Altered Intercellular Communication | An interval of at least 3 months after surgery may be needed to decrease the inflammation of the peripancreas region after SAP. | 24799280 |
| Pleural Effusion, CTCAE, Inflammation, Fever, CTCAE | Altered Intercellular Communication | A 51-year-old man, who had undergone a TLPG at a referring hospital, was referred for fever, elevated inflammation markers, and pleural effusion on postoperative day 3. | 24800528 |
| Inflammation, Anastomotic Leak | Altered Intercellular Communication | A T-tube drainage and wrapping with the intercostal muscle flap is a useful choice of treatment for intrathoracic anastomotic leakage with severe inflammation. | 24800528 |
| Inflammation | Altered Intercellular Communication | Acute or chronic inflammation of soft tissue could be revealed pathologically. | 24800552 |
| Lichen - organism, Fibrosis Assessment, Alopecia, CTCAE, Perifolliculitis | Altered Intercellular Communication | Lichen planopilaris is a type of primary scarring alopecia that is characterized by perifollicular lymphocytic inflammation and fibrosis. | 24800713 |
| Inflammation, Bacterial Infections | Altered Intercellular Communication | Bacterial infection, airway and systemic inflammation and clinical outcomes before and after treatment of AECOPD, a longitudinal and cross-sectional study. | 24800883 |
| Communicable Diseases, Chronic Obstructive Airway Disease, Inflammation | Altered Intercellular Communication | Abstract Bacterial infection is a major cause of acute exacerbations of chronic obstructive pulmonary disease (AECOPD), which are associated with significantly increased airway and systemic inflammation. | 24800883 |
| ARCN1 gene, Inflammation | Altered Intercellular Communication | We measured the airway and systemic inflammation levels, the COPD assessment test (CAT) score and adverse outcomes between patients with and without potentially pathogenic microorganisms (PPM). | 24800883 |
| Inflammation | Altered Intercellular Communication | Our data suggest uncultivated bacteria and/or virus might also play important roles in causing inflammation and AECOPD. | 24800883 |
| Inflammation, Diabetes Mellitus, Non-Insulin-Dependent | Altered Intercellular Communication | Chronic inflammation is a well-known risk factor for type 2 diabetes mellitus (T2DM). | 24800930 |
| Inflammation, Chronic heart failure | Altered Intercellular Communication | Immunosenescence and inflammation characterize chronic heart failure patients with more advanced disease. | 24801091 |
| Inflammation, Congestive heart failure | Altered Intercellular Communication | We hypothesized that patients with CHF may develop immunosenescence due to inflammation and that this may be associated with a worse stage of the disease. | 24801091 |
| Inflammation, Virus Diseases, Bacterial Infections, Malignant Head and Neck Neoplasm | Altered Intercellular Communication | The main risk factor for head and neck cancer is consumption of tobacco and alcohol as well as viral infection and bacterial infection by stimulation of chronic local inflammation. | 24802266 |
| Inflammation, Primary malignant neoplasm | Altered Intercellular Communication | Fucosylation is an oligosaccharide modification associated with cancer and inflammation, which is catalyzed by fucosyltransferases. | 24802742 |
| Inflammation, Diabetes Mellitus, Non-Insulin-Dependent, Cardiovascular Diseases | Altered Intercellular Communication | The systemic chronic inflammation has been postulated to bridge the increased risk of cardiovascular disease and T2D. | 24803740 |
| Inflammation | Altered Intercellular Communication | Furthermore, the calprotectin levels and histological grading of both peri- and intra-tumoral inflammation was not correlated. | 24803811 |
| Vascular Diseases, Inflammation, diabetic | Altered Intercellular Communication | Relation of asymmetric dimethylarginine levels to macrovascular disease and inflammation markers in type 2 diabetic patients. | 24804267 |
| Inflammation, Diabetes Mellitus, Non-Insulin-Dependent, Atherosclerosis | Altered Intercellular Communication | We aimed to determine the relation of asymmetric dimethyl arginine (ADMA) levels to atherosclerotic vascular disease and inflammation markers in type 2 diabetes. | 24804267 |
| Alzheimers Disease", Inflammation, Data types - Address | Altered Intercellular Communication | Alzheimer's disease (AD) has been associated with increased local inflammation in the affected brain regions, and in some studies also with elevated levels of proinflammatory cytokines in peripheral blood. | 24804776 |
| Inflammation, Fibrosis Assessment | Altered Intercellular Communication | Inflammation may play an important role in the pathogenesis of HFpEF because of its significant contribution to myocardial fibrosis. | 24806206 |
| Neurodegenerative Disorders, Inflammation, Endothelial dysfunction | Altered Intercellular Communication | Correlations between inflammation, coagulation activation and neurodegenerative disorders are here supported by the observed variations in plasma levels of markers of coagulation activation and endothelial dysfunction. | 24806325 |
| Inflammation, Abdomen, Renal mass | Altered Intercellular Communication | Abdominal and pelvic MRI revealed periaortic inflammation and a left renal mass, which were F-FDG avid on PET/CT. | 24806606 |
| Inflammation | Altered Intercellular Communication | Epidural biopsy showed chronic inflammation and scattered but not abnormal IgG4-positive cells, possibly related to posttreatment changes. | 24806606 |
| Inflammation, Nerve Degeneration | Altered Intercellular Communication | Clusterin affects inflammation, immune responses, and amyloid clearance, which in turn may result in neurodegeneration. | 24806679 |
| Lacrimal gland cyst, Inflammation | Altered Intercellular Communication | Nine cases showed lacrimal ductal cysts with varying periductal inflammation, and the contents were pinkish, amorphous materials in 7 cases. | 24807540 |
| Inflammation | Altered Intercellular Communication | Inflammatory lesions of the lateral canthal subconjunctival area all originated from lacrimal gland ductules, showing a variable histopathologic spectrum of inflammation and cyst formation. | 24807540 |
| Inflammation, Osteopenia, Dysbiosis | Altered Intercellular Communication | In mice, C3 was required for maximal periodontal inflammation and bone loss, and for the sustenance of the dysbiotic microbiota. | 24808362 |
| Inflammation, Eye pain, Tuberculosis, Pulmonary | Altered Intercellular Communication | Complications that include visual acuity decline, prolonged anterior chamber inflammation, phthisis bulbi, scleral thinning and ocular pain were noted. | 24811050 |
| Inflammation | Altered Intercellular Communication | In this report, we propose eosinophilic inflammation as the precipitant for an aberrant conduction pathway. | 24811559 |
| Inflammatory Bowel Diseases, Gastrointestinal inflammation | Altered Intercellular Communication | Bacteria play a role in the onset and perpetuation of intestinal inflammation in IBD. | 24811995 |
| Refractory anemias, Inflammation | Altered Intercellular Communication | To examine the relationship between inflammation and FoxO expression in RA, and to analyse the mechanisms and biological consequences of FoxO regulation in RA fibroblast-like synoviocytes (FLS). | 24812285 |
| APP gene, Inflammation, Aortic Aneurysm, Abdominal | Altered Intercellular Communication | Abdominal aortic aneurysm (AAA) is characterized as a progressive dilation and degradation of the aortic wall, associated with activation of matrix metalloproteinases (MMPs) and inflammation. | 24812324 |
| APP gene, Inflammation | Altered Intercellular Communication | Our results demonstrate that angiotensin II-sensitive miR-712 and its human homolog miR-205 downregulate TIMP3 and RECK, which in turn stimulate aortic MMP activity and inflammation, leading to AAA development. | 24812324 |
| Inflammation, Diabetes Mellitus, Non-Insulin-Dependent | Altered Intercellular Communication | Altered DNA methylation and differential expression of genes influencing metabolism and inflammation in adipose tissue from subjects with type 2 diabetes. | 24812430 |
| Inflammation, VWF wt Allele, Gingival Hemorrhage | Altered Intercellular Communication | Gingival bleeding in VWD patients (VWD) may be triggered by gingival inflammation and not a genuine symptom. | 24814158 |
| Sepsis, Inflammation | Altered Intercellular Communication | However, some questions remain unanswered, such as whether there is an association between plasma PAI-1 levels and sepsis severity and mortality, and inflammation state during the first week. | 24814968 |
| Inflammation, septic | Altered Intercellular Communication | The most interesting findings of our study, to our knowledge the largest series reporting PAI-1 levels during follow-up in septic patients, were that plasma PAI-1 levels during the first week were associated with inflammation, severity and mortality. | 24814968 |
| Inflammation | Altered Intercellular Communication | The predictors of interest for the ICU patients might be considerably different than those of the general population and other subgroups with systemic inflammation possibly having a pivotal role. | 24814972 |
| Inflammation | Altered Intercellular Communication | Histological inflammation improved after 1 year, (median HAI: 10 vs. 7, P = 0.01) with persistence in 4/5 patients at 3 years (median HAI: 7.5). | 24815494 |
| HTLV-I Infections, Inflammation | Altered Intercellular Communication | Also bitemporal lesions can be the consequence of intense and diffuse inflammation associated with HTLV-1 infection. | 24815740 |
| Amyotrophic Lateral Sclerosis, Inflammation | Altered Intercellular Communication | The cause of ALS is unknown, but inflammation may play a role. | 24816788 |
| Airway structure, ARCN1 gene | Altered Intercellular Communication | Exhaled nitric oxide predicts eosinophilic airway inflammation in COPD. | 24816967 |
| ARCN1 gene, Chronic Obstructive Airway Disease, Asthma, Airway structure | Altered Intercellular Communication | Chronic obstructive pulmonary disease (COPD) with eosinophilic airway inflammation may represent a unique phenotype, possibly with shared features of COPD and asthma. | 24816967 |
| ARCN1 gene, Airway structure | Altered Intercellular Communication | eNO is a good marker to identify COPD patients with eosinophilic airway inflammation. | 24816967 |
| Inflammation, Fracture | Altered Intercellular Communication | High levels of neopterin were associated with increased hip fracture risk, as were some of the kynurenines, suggesting a role of IFN-g-mediated inflammation in the processes leading to hip fracture. | 24817202 |
| Inflammation, Fracture, Osteopenia | Altered Intercellular Communication | Low-grade systemic inflammation has been associated with bone loss and risk of fractures. | 24817202 |
| Inflammation, Fracture | Altered Intercellular Communication | Risk of hip fracture was investigated in relation to markers of inflammation and metabolites in the kynurenine pathway (kynurenines). | 24817202 |
| Inflammation | Altered Intercellular Communication | A biopsy of the area revealed nonspecific, active, chronic inflammation. | 24817241 |
| Granulomatosis, Congenital Abnormality, Unknown (origin) (qualifier value), Infection, Granulomatosis with polyangiitis, polychondritis, Leprosy, Traumatic injury, Syphilis, Systemic Vasculitis | Altered Intercellular Communication | Saddle-nose deformity can occur as a result of trauma to the nose, but it has also been well described in the setting of infections such as leprosy and syphilis and idiopathic inflammatory conditions such as granulomatosis with polyangiitis (formerly known as Wegener granulomatosis) and relapsing polychondritis. | 24817241 |
| Peritonitis, Lymphadenitis, Acute and chronic inflammation, Malignant Neoplasms, Serositis | Altered Intercellular Communication | They included malignant tumors (39 cases), tuberculous peritonitis (28 cases), chronic hepatic inflammation (3 cases), necrotizing lymphadenitis (1 case), and eosinophilic serositis of the small intestine (1 case). | 24818547 |
| Orbital Pseudotumor | Altered Intercellular Communication | There was no evidence of orbital inflammation on history or ocular examination. | 24819206 |
| Communicable Diseases | Altered Intercellular Communication | Contribution of intestinal barrier damage, microbial translocation and HIV-1 infection status to an inflammaging signature. | 24819230 |
| Inflammation, HIV-1 Infection Pathway | Altered Intercellular Communication | Systemic inflammation is a characteristic of both HIV-1 infection and aging ("inflammaging"). | 24819230 |
| HIV Antigens | Altered Intercellular Communication | Intestinal epithelial barrier damage (IEBD) and microbial translocation (MT) contribute to HIV-associated inflammation, but their impact on inflammaging remains unclear. | 24819230 |
| Inflammation, HIV-1 Infection Pathway | Altered Intercellular Communication | Systemic inflammation is a characteristic of both HIV-1 infection and aging ("inflammaging"). | 24819230 |
| HIV Antigens | Altered Intercellular Communication | Intestinal epithelial barrier damage (IEBD) and microbial translocation (MT) contribute to HIV-associated inflammation, but their impact on inflammaging remains unclear. | 24819230 |
| Inflammation | Altered Intercellular Communication | We describe a novel IP that incorporates biomarkers of IEBD, MT, immune activation as well as inflammation. | 24819230 |
| Communicable Diseases, Inflammation | Altered Intercellular Communication | Radiographs revealed osseointegration and stable periimplant marginal bone level with no signs of infection or inflammation. | 24819533 |
| Inflammation, Primary malignant neoplasm, Cardiovascular Diseases | Altered Intercellular Communication | To determine whether resveratrol levels achieved with diet are associated with inflammation, cancer, cardiovascular disease, and mortality in humans. | 24819981 |
| Inflammation, Tumor necrosis, Cardiovascular Diseases | Altered Intercellular Communication | Secondary outcomes were markers of inflammation (serum C-reactive protein [CRP], interleukin [IL]-6, IL-1b, and tumor necrosis factor [TNF]) and prevalent and incident cancer and cardiovascular disease. | 24819981 |
| Inflammation, "Alzheimers Disease | Altered Intercellular Communication | Relationship between b-Secretase, inflammation and core cerebrospinal fluid biomarkers for Alzheimer's disease. | 24820015 |
| Inflammation, Impaired cognition, Trauma, Nervous System, Presenile dementia, "Alzheimers Disease", Anomia, Frontotemporal dementia | Altered Intercellular Communication | We measured markers of amyloid-b protein precursor (AbPP) processing (Ab42, sAbPPb, b-secretase activity), neuronal damage (total tau, p-tau), and inflammation (YKL-40) in CSF from 194 participants with the following diagnoses: subjective cognitive impairment or non-amnestic mild cognitive impairment (na-SCI, n = 44), amnestic mild cognitive impairment (aMCI, n = 45), dementia of the Alzheimer type (DAT, n = 59), frontotemporal dementia (FTD, n = 22), and 24 cognitively normal controls. | 24820015 |
| Inflammation, Data types - Address, Frontotemporal dementia | Altered Intercellular Communication | This suggests that inflammation is a common feature in AD and FTD. | 24820015 |
| Amyotrophic Lateral Sclerosis | Altered Intercellular Communication | These findings suggest that EPO may be a potential therapeutic candidate having ability to modulate immune-inflammation in ALS. | 24820540 |
| Inflammation, Sarcoidosis | Altered Intercellular Communication | Tartrate-resistant acid phosphatase 5a in sarcoidosis: further evidence for a novel macrophage biomarker in chronic inflammation. | 24820632 |
| Inflammation, Sarcoidosis | Altered Intercellular Communication | These findings further support our hypothesis that serum TRACP5a is derived from systemic inflammatory MPh and thereby may be a biomarker of inflammation for sarcoidosis and also reflect its disease activity. | 24820632 |
| Inflammation, Ascites | Altered Intercellular Communication | A diagnostic laparoscopy with multiple diagnostic biopsies was carried out, but no macroscopic cause of the ascites was found; histopathological examination showed minimal aspects of diffuse and non-specific chronic inflammation. | 24820919 |
| Heart Diseases, Communicable Diseases, Inflammation, Atherosclerosis | Altered Intercellular Communication | Evidence suggests that the inflammation caused by infection is associated with the development of atherosclerosis and heart disease. | 24820983 |
| Degenerative polyarthritis, Pain Distress Question, Inflammation | Altered Intercellular Communication | Knee pain and inflammation in the infrapatellar fat pad estimated by conventional and dynamic contrast-enhanced magnetic resonance imaging in obese patients with osteoarthritis: a cross-sectional study. | 24821663 |
| Inflammation, Knee pain, Osteoarthritis, Knee | Altered Intercellular Communication | To investigate the association between knee pain and signs of inflammation in the infrapatellar fat pad (IPFP) in obese patients with knee osteoarthritis (KOA). | 24821663 |
| Pain Distress Question | Altered Intercellular Communication | The bivariate association between KOOS pain and the DCE-MRI perfusion variable "Inflammation" showed a statistically significant correlation (r = -0.42, P < 0.0001). | 24821663 |
| Inflammation, Pain Distress Question | Altered Intercellular Communication | Perfusion variables on DCE-MRI reflecting the severity of inflammation in the IPFP and MOAKS Hoffa-synovitis were associated with the severity of pain in KOA. | 24821663 |
| Inflammation, Pain Distress Question | Altered Intercellular Communication | These results suggest that severe inflammation in the IPFP is associated with severe pain in KOA and that DCE-MRI is a promising method to study the impact of inflammation in KOA. | 24821663 |
| Liver carcinoma, Neoplasms | Altered Intercellular Communication | Comparison of inflammation-based prognostic scores as predictors of tumor recurrence in patients with hepatocellular carcinoma after curative resection. | 24823966 |
| FAM126A gene | Altered Intercellular Communication | Preoperative NLR is an independent predictor of RFS in patients with HCC after curative hepatectomy, and is superior to the other inflammation-based prognostic scores. | 24823966 |
| Inflammation, Overweight | Altered Intercellular Communication | Prevalence of tissue iron deficiency (sTfR >113.3 nmol/l; 30.6 vs 12.5%; P=0.002) and chronic inflammation (AGP >25 mmol/l; 19 vs 10%; P=0.025) were higher in overweight than in normal-weight children. | 24824017 |
| Overweight | Altered Intercellular Communication | The role of adiposity-related inflammation in tissue iron deficiency should be considered even when the prevalence of overweight is relatively low. | 24824017 |
| Liver parenchyma, Inflammation, Hepatitis B, Complete atrioventricular block, Hepatitis B, Chronic | Altered Intercellular Communication | To investigate the relationship between the expression of hepatitis B virus (HBV) core antigen and viral replication and liver tissue inflammation damage in chronic hepatitis B (CHB) patients, and to analyze the relationship of core antigen expression differences with clinical and pathological features in e antigen-negative and e antigen-positive CHB patients. | 24824119 |
| Inflammation, Fibrosis Assessment, Complete atrioventricular block | Altered Intercellular Communication | Also for the e antigen-positive CHB patients, the HBV DNA titer was positively correlated with the rank level of pulp karyotype in core antigen expression (r = 0.589, P = 0.003) but negatively correlated with lobular inflammation, interface inflammation, and fibrosis level (r = -0.552, P = 0.000; r = -0.381, P = 0.008; r = -0.555, P = 0.000); in addition, the level of peripheral blood lymphocytes was negatively correlated with lobular inflammation and fibrosis level (r = -0.361, P = 0.012; r = -0.356, P = 0.013). | 24824119 |
| ARCN1 gene, Airway structure, Chronic Obstructive Airway Disease, Lung Diseases, Obstructive, Asthma | Altered Intercellular Communication | Catalase (CAT) is a part of the active antioxidant defense system and has been studied with regard to its association with asthma and chronic obstructive pulmonary disease (COPD), which are heterogeneous obstructive pulmonary diseases characterized by chronic airway inflammation. | 24824229 |
| Airway structure | Altered Intercellular Communication | Asthma is characterized by chronic airway inflammation and remodeling. | 24824230 |
| Eosinophilic inflammation | Altered Intercellular Communication | Levels of serum high-sensitivity C-reactive protein (hs-CRP) reflect airway eosinophilic inflammation. | 24824230 |
| ARCN1 gene, Inflammation, Cardiovascular Diseases, Cyclophosphamide/Vincristine/Dacarbazine Regimen, Chronic Obstructive Airway Disease | Altered Intercellular Communication | Inflammation and oxidative stress play an essential role in the pathogenesis of chronic obstructive pulmonary disease (COPD) and cardiovascular disease (CVD). | 24824617 |
| ARCN1 gene, Inflammation | Altered Intercellular Communication | The echocardiographic parameters of cardiac function correlate with the markers of inflammation in patients with COPD, which emphasizes the inflammatory background of CVD. | 24824617 |
| Inflammatory Bowel Diseases, Inflammation, hepcidin, Anemia | Altered Intercellular Communication | Hepcidin, a key mediator in this anemia, is up-regulated by high iron levels and inflammation, and serum levels are elevated in IBD. | 24825446 |
| Inflammation, Carcinogenesis, Disease, Hyperuricemia | Altered Intercellular Communication | Inflammation and hyperuricaemia, which are the major characteristics of gout disease, are thought to be associated with carcinogenesis and anti-carcinogenesis, respectively. | 24825466 |
| Sinusitis, Vasculitis, CTCAE | Altered Intercellular Communication | This case highlights the spectrum of vasculitic conditions that may be associated with cavernous sinus inflammation. | 24827146 |
| Inflammation, Critical Illness | Altered Intercellular Communication | Our results suggest that in nontrauma critically ill patients, acute alcohol exposure diminishes inflammation and increases numbers of circulating B and T lymphocytes. | 24827394 |
| Inflammation, polyps | Altered Intercellular Communication | We speculate that the compaction of the fecal mass in the appendix triggered mucosal inflammation, resulting in the formation of the polyp, which concealed both the feces and appendiceal orifice. | 24827483 |
| Inflammation, Arthritis, Psoriatic, atherosclerotic | Altered Intercellular Communication | Increased burden of inflammation over time is associated with the extent of atherosclerotic plaques in patients with psoriatic arthritis. | 24827532 |
| PROS1 gene, Inflammation, Arthritis, Psoriatic, Atherosclerosis | Altered Intercellular Communication | To investigate whether a higher burden of inflammation is associated with more severe atherosclerosis in patients with psoriatic arthritis (PsA). | 24827532 |
| Inflammation, Atherosclerosis | Altered Intercellular Communication | The association between inflammation over time and atherosclerosis was assessed by regression models adjusted for age, sex and cardiovascular risk factors. | 24827532 |
| Inflammation, Atherosclerosis | Altered Intercellular Communication | Exposure to an increased burden of inflammation is associated with more severe atherosclerosis in patients with PsA. | 24827532 |
| Inflammation, Tooth Loss, Obesity | Altered Intercellular Communication | Sex Differences of Tooth Loss and Obesity on Systemic Markers of Inflammation. | 24828384 |
| Inflammation, Periodontitis, Tooth Loss, Obesity | Altered Intercellular Communication | Sex-specific differences in the incidence of periodontitis and tooth loss may be related to different phenotypes of obesity and their associations with low-grade inflammation. | 24828384 |
| Inflammation, Electrocardiogram: myocardial infarction (finding), Occlusive vascular disease, Cerebrovascular accident | Altered Intercellular Communication | Inflammation plays a key role in the pathogenesis of vascular occlusive diseases, such as myocardial infarction and stroke. | 24829443 |
| Inflammation, Occlusive vascular disease | Altered Intercellular Communication | We hypothesized that the inflammation induced by surgery itself augments vascular occlusive disease. | 24829443 |
| Inflammation, Hypoperfusion | Altered Intercellular Communication | Furthermore, postoperative CRP elevation was associated with intraoperative parameters reflecting hypoperfusion and inflammation. | 24829443 |
| Inflammation | Altered Intercellular Communication | In conclusion, eosinophils triggered a more severe form of inflammation in CRSwNP compared with non-eosinophilic inflammatory cells. | 24830325 |
| Degenerative polyarthritis, Cartilage destruction | Altered Intercellular Communication | Supplementation with exogenous H2S sources can regulate the expression of relevant genes in OA pathogenesis and progression, counteracting IL1b pro-inflammatory signals that lead to cartilage destruction in part by reducing NFkB activation. | 24831018 |
| Orbital Pseudotumor | Altered Intercellular Communication | He first presented with right orbital inflammation that did not improve despite antibiotic treatment. | 24831308 |
| Inflammation | Altered Intercellular Communication | Computer tomography (CT) of the orbits showed a soft tissue mass along the roof of the orbit, which was biopsied, revealing acute on chronic inflammation. | 24831308 |
| Orbital Pseudotumor | Altered Intercellular Communication | There was complete resolution of his orbital inflammation within 2 weeks of initiating systemic steroid treatment. | 24831308 |
| Orbital Pseudotumor | Altered Intercellular Communication | He subsequently developed recurrent bouts of left orbital inflammation. | 24831308 |
| Necrotizing granulomatous inflammation | Altered Intercellular Communication | Final histopathologic diagnosis of the lesion was confirmed as chronic granulomatous inflammation, combined with the neurosyphilis history, spinal dural syphilis granuloma was finally diagnosed. | 24831378 |
| Lung hyperinflation, Airway Obstruction, Hypoxemia, Inflammation | Altered Intercellular Communication | Airway obstruction, lung hyperinflation, markers of systemic inflammation and cardiovascular health, exacerbation frequency, smoking habits, and body composition were tested as possible predictors of PaO2 and first episode of hypoxemia. | 24831555 |
| Inflammation | Altered Intercellular Communication | Five patients had magnetic resonance imaging showing asymmetry of the vulva with no enhanced signaling associated with inflammation. | 24832171 |
| Inflammation, Weight decreased | Altered Intercellular Communication | Exercise training reduces systemic inflammation in weight-stable people, but concurrent diet-induced body weight loss is not well studied. | 24832193 |
| Inflammation, Overweight | Altered Intercellular Communication | These findings indicate that resistance training is an effective means for older, overweight adults to reduce systemic inflammation. | 24832193 |
| Inflammation, Chronic Obstructive Airway Disease | Altered Intercellular Communication | Evaluating the role of inflammation in chronic airways disease: the ERICA study. | 24832197 |
| Pain Distress Question, Sinusitis | Altered Intercellular Communication | The authors present here a 56-year-old man who complained of isolated OD pain with no evidence of cerebral or sinus inflammation on imaging. | 24833448 |
| Inflammation, Thrombosis | Altered Intercellular Communication | Von Willebrand factor (VWF), a key player in hemostasis and thrombosis, is released from endothelial cells during inflammation. | 24833640 |
| Inflammation, Dental Plaque | Altered Intercellular Communication | Positron emission tomography employing [(18)F]fluorodeoxyglucose can visualize plaque inflammation; however, the question remains whether this is specific for plaque vulnerability. | 24834996 |
| Inflammation, Autoimmune Pancreatitis, Fibrosis Assessment | Altered Intercellular Communication | Autoimmune pancreatitis is a benign process characterized by inflammation and fibrosis. | 24835039 |
| Inflammation, Thyroid associated opthalmopathies, Strabismus | Altered Intercellular Communication | Thyroid ophthalmopathy activity was defined using the VISA (vision, inflammation, strabismus, and appearance/exposure) classification for TED. | 24835350 |
| Inflammation, Fever, CTCAE, Inflammatory disorder | Altered Intercellular Communication | Autoinflammatory diseases represent an expanding spectrum of genetic and non-genetic inflammatory diseases characterized by recurrent episodes of fever and systemic inflammation, affecting joints, skin and serosal surfaces. | 24835548 |
| Inflammatory abnormality of the eye | Altered Intercellular Communication | Severe ocular surface inflammation with fibrovascular tissue surrounded the PED in all 10 eyes. | 24835597 |
| Vitreous inflammatory cells | Altered Intercellular Communication | Objective measurement of vitreous inflammation using optical coherence tomography. | 24835759 |
| Vitreoretinal Area, Intraocular inflammation, Panuveitis, Uveitis, Vitreous haze | Altered Intercellular Communication | Thirty patients (30 eyes) with vitreous haze secondary to intermediate, posterior, or panuveitis; 12 patients (12 eyes) with uveitis but without evidence of vitreous haze; and 18 patients (18 eyes) without intraocular inflammation or vitreoretinal disease. | 24835759 |
| Respiratory Distress Syndrome, Adult, Inflammation, Respiratory Distress Syndrome, Newborn, Single organ dysfunction | Altered Intercellular Communication | In the acute respiratory distress syndrome (ARDS), inflammation in the lungs and other organs can cause life-threatening organ failure. | 24835849 |
| Inflammation, fibroblast proliferation | Altered Intercellular Communication | Mammalian target of rapamycin (mTOR), a central mediator of inflammation, has been proposed as a novel target to block fibroproliferation. | 24835866 |
| Inflammation, Liver carcinoma | Altered Intercellular Communication | Radioembolization of hepatocellular carcinoma activates liver regeneration, induces inflammation and endothelial stress and activates coagulation. | 24836705 |
| Inflammation, Hepatobiliary Disorder, Thrombosis, Venoocclusive disease | Altered Intercellular Communication | Radioembolization may rarely induce liver disease resulting in a syndrome that is similar to veno-occlusive disease complicating bone marrow transplantation where inflammation, endothelial cell activation and thrombosis are likely involved. | 24836705 |
| Myofibrils, Inflammation, Vascular Diseases, Fibrosis Assessment, Hypertrophic Cardiomyopathy | Altered Intercellular Communication | Semi-quantitative histological analysis revealed no significant differences in the degree of myocardial hypertrophy, myofibrillar loss, fibrosis, small vascular disease, inflammation or fat invasion between LD/DM and non-LD cases. | 24836730 |
| Inflammation, "Alzheimers Disease", Data types - Address | Altered Intercellular Communication | Physical activity influences inflammation, and both affect brain structure and Alzheimer's disease (AD) risk. | 24836855 |
| Inflammation, Data types - Address | Altered Intercellular Communication | TNFa, but not physical activity, was associated with regional volumes of the inferior parietal lobule, a region previously associated with inflammation in AD patients. | 24836855 |
| Tooth structure, Osteopenia, Pulpitis | Altered Intercellular Communication | This condition causes bone loss around the apex of the tooth, subsequent to pulp inflammation (pulpitis). | 24837500 |
| SNCG gene, Inflammation, palladium, Parkinson Disease | Altered Intercellular Communication | Increased gut permeability, inflammation, and colonic a-synuclein pathology are present in early Parkinson's disease (PD) and have been proposed to contribute to PD pathogenesis. | 24838182 |
| Inflammation, Atherosclerosis | Altered Intercellular Communication | Heat-shock protein 60 (Hsp60) has been shown to provoke inflammation, and anti-Hsp60 may facilitate the development of atherosclerosis. | 24838263 |
| Inflammation, Liver Dysfunction | Altered Intercellular Communication | Because of synthesis by the liver, production of CRP in response to inflammation may be attenuated in patients with liver dysfunction. | 24838501 |
| Inflammation, Arthritis | Altered Intercellular Communication | Inhibition of terminal FUTs reshapes the differentiation and functions of M1 macrophages, leading to resolution of inflammation in arthritis. | 24838610 |
| Inflammation, Thrombosis, Endothelial dysfunction | Altered Intercellular Communication | It is known that eosinophils play an important role in inflammation, endothelial dysfunction, and thrombosis. | 24838897 |
| FBN2 wt Allele | Altered Intercellular Communication | Prostaglandin E2 (PGE2) involves in progression of various chronic inflammation-related cancers including cholangiocarcinoma (CCA). | 24839005 |
| Inflammation, Primary malignant neoplasm, Chronic disease | Altered Intercellular Communication | Systemic measures of chronic inflammation, often based on a single blood draw, are frequently used to study the associations between inflammation and chronic diseases such as cancer. | 24839050 |
| Inflammation, Hypertrophy | Altered Intercellular Communication | The physical examination revealed marked enlargement with inflammation in his right hemiscrotum. | 24841026 |
| Atherogenesis, Inflammation, Obesity, Diabetes Mellitus | Altered Intercellular Communication | Peroxisome proliferator-activated receptor g (PPARg) is a ligand-activated transcription factor involved in the regulation of lipid metabolism, diabetes, obesity, atherogenesis and inflammation. | 24841086 |
| Inflammation, Leukocytosis, Fever, CTCAE, Candida (fungus) | Altered Intercellular Communication | We identified patients who from January 2010 to June 2012 had signs of inflammation, such as fever and leukocytosis, and concomitant positive cultures of Candida spp. | 24841623 |
| Inflammation, Primary malignant neoplasm | Altered Intercellular Communication | Matrix metalloproteinases (MMPs) appear to be responsible for much of the extracellular matrix (ECM) degradation observed in the progression of cancer, aging and inflammation. | 24841706 |
| Inflammation | Altered Intercellular Communication | Giant cells and chronic sclerosing inflammation were absent. | 24841730 |
| Right sided, Inflammation, Arthritis, Psoriatic | Altered Intercellular Communication | A 48-year-old woman who received injections of adalimumab for the treatment of psoriatic arthritis developed right-sided orbital pain and inflammation. | 24841734 |
| Inflammation, Swelling | Altered Intercellular Communication | We present a case of 35-year-old young man with diffuse swelling of 3.5x4 cm in the parotid region on the right side of the face with signs of inflammation. | 24842360 |
| Inflammation, Appendicitis, CTCAE | Altered Intercellular Communication | While the presence of secondary signs of inflammation can be used to rule in appendicitis, statistical strength to rule out appendicitis in the absence of secondary signs is insufficient. | 24842505 |
| Muscle Rigidity, Inflammation, Fever, CTCAE | Altered Intercellular Communication | Crowned dens syndrome (CDS) is a clinical-radiological entity characterized by acute attacks of neck pain with fever, rigidity, general signs of inflammation, and calcification of the periodontoid articular structures. | 24842523 |
| Interstitial inflammation | Altered Intercellular Communication | The impact on graft survival of interstitial inflammation in borderline change of allograft kidneys. | 24842816 |
| Interstitial inflammation | Altered Intercellular Communication | In this study, we focused specifically on interstitial inflammation as a factor influencing outcome after diagnosis of BL. | 24842816 |
| Interstitial inflammation | Altered Intercellular Communication | Univariate analysis showed that the grade of interstitial inflammation was not a significant risk factor for developing acute rejection (P = 0.816). | 24842816 |
| Interstitial inflammation | Altered Intercellular Communication | Our results show that the level of interstitial inflammation does not have an effect on a progressive BL course. | 24842816 |
| Interstitial inflammation, Glomerulitis Assessment, Interstitial Fibrosis Assessment, Peritubular Capillaritis Assessment, Tubular atrophy | Altered Intercellular Communication | Peritubular capillaritis was present in 74 BS (86%), transplant glomerulitis in 65 (76%), interstitial fibrosis and tubular atrophy (IF/TA) in 71 (83%), thickening of the peritubular capillary (PTC) basement membrane in 72 (84%), and interstitial inflammation in 40 (47%). | 24842817 |
| Glomerulitis Assessment, Inflammation, Peritubular Capillaritis Assessment, Transplant glomerulopathy | Altered Intercellular Communication | We suggest that histopathological changes of transplant glomerulopathy might be accompanied by inflammation of the microvasculature, such as transplant glomerulitis and peritubular capillaritis, thickening of the peritubular capillary basement membrane, and circulating anti-HLA antibodies. | 24842817 |
| Tubulitis Assessment, Interstitial inflammation | Altered Intercellular Communication | In the latter, focal interstitial inflammation and severe tubulitis without cytopathic changes were identified outside of SV40-positive areas. | 24842821 |
| Inflammation, Bipolar Disorder, Diabetes Mellitus, Non-Insulin-Dependent, Diabetes Mellitus | Altered Intercellular Communication | The association between depressive symptoms and systemic inflammation in people with type 2 diabetes: findings from the South London Diabetes Study. | 24842983 |
| Inflammation, Diabetes Mellitus, Non-Insulin-Dependent, Bipolar Disorder | Altered Intercellular Communication | Increased inflammation may be involved in the pathogenesis of depressive symptoms in type 2 diabetes and contribute to the increased risk of complications and mortality in this group. | 24842983 |
| Inflammation, Prostate carcinoma | Altered Intercellular Communication | Inflammation has been hypothesized to play an important etiological role in the initiation or progression of prostate cancer. | 24844401 |
| Inflammation, Prostate carcinoma | Altered Intercellular Communication | Circulating levels of the systemic inflammation marker C-reactive protein (CRP) have been associated with increased risk of prostate cancer. | 24844401 |
| Minimal Disseminated Disease, Inflammation, Bipolar Disorder | Altered Intercellular Communication | Significant associations between inflammation and depressive symptoms were found for CRP and IL-6, for the total group and the subgroup of patients with current MDD. | 24845191 |
| Inflammation, Rheumatoid Arthritis, Atherosclerosis | Altered Intercellular Communication | Systemic inflammation and cardiovascular risk factors predict rapid progression of atherosclerosis in rheumatoid arthritis. | 24845391 |
| Inflammation | Altered Intercellular Communication | CV risk factors may modify the role of systemic inflammation in determining IMT progression over time. | 24845391 |
| Sinusitis, Craniosynostosis, Chronic sinusitis | Altered Intercellular Communication | Twelve chronic rhinosinusitis (CRS) patients presenting with maxillary sinus inflammation requiring FESS were enrolled. | 24845735 |
| Inflammation, Data types - Address | Altered Intercellular Communication | This finding could be explained by inflammation and/or gliosis in early stages of AD. | 24846203 |
| Inflammation, Rheumatic mitral stenosis | Altered Intercellular Communication | In patients with rheumatic mitral stenosis (RMS), ongoing chronic inflammation may resultin the progression of valvular damage and the formation of spontaneous echocardiographic contrast (SEC). | 24846361 |
| Inflammation | Altered Intercellular Communication | The formation of SEC is associated with inflammation and NLR is an independent predictive risk factor for SEC. | 24846361 |
| Vasculitis | Altered Intercellular Communication | Vasculitides includes a heterogeneous group of disorders with the common histologic findings of vascular wall inflammation. | 24846840 |
| vascular inflammations, Vasculitis, CTCAE | Altered Intercellular Communication | Potential isolated gynecologic vasculitis causes include: previous surgical interventions and vascular inflammation secondary to local neoplasm. | 24846840 |
| vascular inflammations, Hypertriglyceridemia, Obesity, Diabetes Mellitus | Altered Intercellular Communication | Obesity, hypertriglyceridemia and raised CRP are interrelated suggesting that obesity is not only linked to hypertriglyceridemia but vascular inflammation among pre-obese and obese without overt diabetes mellitus causes high CRP as well and this can be used as a marker to predict the future risk of CAD. | 24848386 |
| Inflammation | Altered Intercellular Communication | Recently, we identified novel roles of Substance-P (SP) in the suppression of the injury-mediated inflammation and also in stem cell mobilization. | 24849674 |
| Inflammation | Altered Intercellular Communication | Predicted metagenomes of particular microbiota members involved in these compositional shifts indicated exacerbation-associated loss of functions involved in the synthesis of antimicrobial and anti-inflammatory products, alongside enrichment in functions related to pathogen-elicited inflammation. | 24850358 |
| Inflammatory Bowel Diseases | Altered Intercellular Communication | Data indicate that SIRT1 is downregulated in IBD patients and colitic mice and suggest that SIRT1 activation can help attenuate inflammatory signals in the gut. | 24850427 |
| Inflammation | Altered Intercellular Communication | More needs to be learned about the complex interaction between stress, immune parameters and chronic inflammation. | 24850878 |
| Inflammation, Pancreatitis | Altered Intercellular Communication | Mild and moderate severe acute pancreatitis is an illness characterized with chemical inflammation which, in general, passes without major complications. | 24851605 |
| Inflammation, Carcinoma of lung, Cyclophosphamide/Vincristine/Dacarbazine Regimen, Cardiovascular Diseases | Altered Intercellular Communication | Inflammation is involved in development of lung cancer and cardiovascular disease (CVD), and we hypothesize that self-reported CVD is an independent risk factor for lung cancer. | 24852520 |
| Granulomatous inflammation, Granulomatous prostatitis, prostatitis | Altered Intercellular Communication | Granulomatous prostatitis is an unusual form of prostatitis, and xanthogranulomatous prostatitis (XGP) is an even rarer granulomatous inflammation. | 24852675 |
| Inflammation, Hantavirus Infections, Sepsis, HHH syndrome, Hematological Disease | Altered Intercellular Communication | These findings suggest that HHH is a different entity from HPS and that it preferentially develops under conditions of excessive inflammation and its associated risks, such as hematological diseases and sepsis. | 24852692 |
| Fibrosis Assessment, Tubular atrophy, Albuminuria | Altered Intercellular Communication | Albuminuria may further lead to tubulointerstitial inflammation, fibrosis and tubular atrophy. | 24853042 |
| Inflammation, Gastrointestinal inflammation | Altered Intercellular Communication | Inhibition of inflammation with IFX would reduce the bacterial toxins via improvement of intestinal inflammation. | 24853095 |
| Inflammation | Altered Intercellular Communication | There was a significant persistent correlation between endoscopic inflammation and fecal calprotectin (p = 0.003 at inclusion and p < 0.001 at follow-up). | 24853318 |
| Inflammation | Altered Intercellular Communication | CRP was correlated to endoscopic inflammation at inclusion (p = 0.006), but not at follow-up. | 24853318 |
| Shock, Inflammation, Metabolic acidosis | Altered Intercellular Communication | We have identified two subphenotypes within ARDS, one of which is categorised by more severe inflammation, shock, and metabolic acidosis and by worse clinical outcomes. | 24853585 |
| Pseudotumor, Orbital Pseudotumor | Altered Intercellular Communication | IgG4-related orbital inflammation presenting as unilateral pseudotumor. | 24854367 |
| Swelling | Altered Intercellular Communication | It is an inflammatory condition of unknown etiology characterized by tumorous swelling of the organs, characteristic histopathologic changes and elevated IgG4: IgG plasma cells ratio. | 24854367 |
| Chronic Kidney Diseases | Altered Intercellular Communication | Soluble TM may play critical roles in the development of CKD, as a biomarker of endothelial cells damage, anticoagulation and anti-inflammation. | 24854597 |
| Inflammation, Acute inflammation, Pancreatitis, Alcoholic | Altered Intercellular Communication | The possibility of acute bacterial inflammation should be considered in all cases of chronic alcoholic pancreatitis who present with severe features of inflammation, even in the early stages of an attack. | 24854608 |
| Inflammation, Depression, CTCAE, Bipolar Disorder | Altered Intercellular Communication | Depressive symptoms are associated with inflammation yet the association between inflammation and different levels of depression remains unclear. | 24856570 |
| Inflammation | Altered Intercellular Communication | Among participants not taking anti-depressants, subsyndromal depression is not associated with inflammation. | 24856570 |
| Inflammation, Bipolar Disorder | Altered Intercellular Communication | However, depressive symptoms measured by CES-D>=16 are associated with a lower inflammation (CRP). | 24856570 |
| Inflammation, Neoplasms | Altered Intercellular Communication | Risk factors were identified in 92 patients (79%) including prior surgery, inflammation, and extensive tumor. | 24857278 |
| Prolactinoma, "Pituitary-dependent Cushings disease", Acromegaly | Altered Intercellular Communication | Hormonal remission was achieved in 16 patients with Cushing disease (84%), 18 patients with prolactinoma (78.2%), and 18 patients with acromegaly (85,7%). | 24857341 |
| Inflammation, Sinusitis | Altered Intercellular Communication | Sinusitis is defined as a condition manifested by inflammation of the mucous membrane of the nose & paranasal sinuses, fluid within this cavities and or underlying bone. | 24858147 |
| Degenerative polyarthritis, Inflammation, Cartilage damage | Altered Intercellular Communication | Altogether, our findings support a beneficial effect of HA/sorbitol in OA through the restoration of redox status and reduction of apoptosis, inflammation and catabolism involved in cartilage damage. | 24858301 |
| Inflammation | Altered Intercellular Communication | Telomere attrition has been associated with age-related diseases, although causality is unclear and controversial; low-grade systemic inflammation (inflammaging) has also been implicated in age-related pathogenesis. | 24858709 |
| Inflammation | Altered Intercellular Communication | Telomere attrition has been associated with age-related diseases, although causality is unclear and controversial; low-grade systemic inflammation (inflammaging) has also been implicated in age-related pathogenesis. | 24858709 |
| Sepsis, Inflammation, Hyperinsulinism, Hypoxia | Altered Intercellular Communication | However, its expression reportedly varies in response to a range of pathophysiological variables (inflammation, oxidative stress, hyperinsulinaemia, hypoxia) which feature prominently in sepsis. | 24858725 |
| Inflammation, Traumatic injury | Altered Intercellular Communication | Mediators of inflammation have been postulated as playing a key role in being responsible for life threatening complications of multiple trauma patients. | 24858965 |
| Inflammation, Dyssomnias, Medically Unexplained Symptoms, Bipolar Disorder, Fatigue | Altered Intercellular Communication | Our findings indicate that the link between depressive symptoms and systemic inflammation may be due to the somatic symptoms of sleep disturbance, fatigue, appetite changes, and psychomotor retardation/agitation and may be strongest among non-Hispanic Whites. | 24859042 |
| Inflammatory Bowel Diseases, Inflammation, Primary malignant neoplasm | Altered Intercellular Communication | Expression stability of common housekeeping genes is differently affected by bowel inflammation and cancer: implications for finding suitable normalizers for inflammatory bowel disease studies. | 24859296 |
| Primary malignant neoplasm, Colitis | Altered Intercellular Communication | Colon inflammation affected HKG more pronouncedly than cancer with ACTB significantly down- and B2M upregulated. | 24859296 |
| Sleep-Disordered Breathing, Inflammation, Hypoxia, Cardiovascular Diseases | Altered Intercellular Communication | Sleep disordered breathing, hypoxia and inflammation: associations with sickness behaviour in community dwelling elderly with and without cardiovascular disease. | 24859483 |
| Inflammation, Pain Distress Question, Illness Behavior, Syndrome, Sleep disturbances, Bipolar Disorder, Fatigue | Altered Intercellular Communication | Inflammation can induce a cluster of symptoms, referred to as sickness behaviour (e.g., depressive symptoms, sleep disturbances, pain and fatigue). | 24859483 |
| Sleep-Disordered Breathing, Inflammation, Hypoxia, Cyclophosphamide/Vincristine/Dacarbazine Regimen | Altered Intercellular Communication | CVD is associated with an increased inflammatory activity and in SDB, hypoxia can also increase inflammation. | 24859483 |
| Inflammation, Hypoxia | Altered Intercellular Communication | The purpose of this study is to explore if SDB-related hypoxia is associated differently with inflammation and the presence of sickness behaviour in older adults with and without CVD. | 24859483 |
| Illness Behavior, Inflammation, Hypoxia, Bipolar Disorder | Altered Intercellular Communication | Structural Equation Modelling showed that SDB-related hypoxia was associated with inflammation (b > 0.40) which mediated indirect associations with sickness behaviour (b = 0.19) and depressive symptoms (b = 0.11), but only in those with CVD (n = 119). | 24859483 |
| Inflammation, Colorectal Carcinoma | Altered Intercellular Communication | Considerable evidence has suggested that chronic inflammation is a causative factor in the development of human colorectal cancer (CRC). | 24859972 |
| Orchitis | Altered Intercellular Communication | The entheses represent the initial site of articular inflammation and the enthesis of the Achilles tendon is the first to be affected. | 24861143 |
| Chronic inflammation | Altered Intercellular Communication | Pentraxin (PTX) 3 is an acute phase protein known to be associated with chronic inflammation. | 24861165 |
| Inflammation, Spondylitis | Altered Intercellular Communication | This study was performed to test the hypothesis that serum PTX3 levels might be elevated as a marker of inflammation in patients with ankylosing spondylitis. | 24861165 |
| Inflammation, Spondylitis | Altered Intercellular Communication | These results are supportive of the hypothesis that levels of serum PTX 3 might be elevated in association with inflammation in patients with ankylosing spondylitis; however, results also demonstrate that there is no significant correlation with disease activity. | 24861165 |
| Inflammation, Pneumonia, Interstitial, Pulmonary Fibrosis | Altered Intercellular Communication | Interstitial pneumonia (IP) is characterized by various degrees of pulmonary fibrosis and inflammation. | 24861259 |
| Gingivitis, Periodontitis | Altered Intercellular Communication | In Case 1, generalized chronic periodontitis with severe gingival inflammation was treated with azithromycin before periodontal treatment. | 24861402 |
| Gingivitis | Altered Intercellular Communication | This property may be independent of the degree of baseline gingival inflammation. | 24861402 |
| Malignant neoplasm of urinary bladder, Transitional cell carcinoma of bladder, Inflammation, Malignant Neoplasms | Altered Intercellular Communication | To assess whether polymorphisms of the interleukin-23 receptor (IL23R) gene are associated with bladder transitional cell carcinoma because chronic inflammation contributes to bladder cancer and the IL23R is known to be critically involved in the carcinogenesis of various malignant tumors. | 24861772 |
| Inflammation, Carcinogenesis, Neoplasms | Altered Intercellular Communication | Inflammation mediated by the immune system is known to be important in carcinogenesis and, specifically, T helper 17 cells have been reported to play a role in tumor progression by promoting neo-angiogenesis. | 24861949 |
| Airway structure, Asthma, Respiration Disorders | Altered Intercellular Communication | Bronchial asthma is a chronic respiratory disease characterized by airway inflammation. | 24863266 |
| Airway structure, Disease | Altered Intercellular Communication | There is increasing evidence that neurotrophins play an important role in the development and maintenance of neurogenic airway inflammation in chronic allergic diseases. | 24863266 |
| Hyperlipidemia, Hepatic inflammation | Altered Intercellular Communication | Consumption of trans-fat for 20 weeks resulted in remarkable hyperlipidemia, elevation of serum cholesteryl ester transfer protein activity, hepatic inflammation, and fatty liver changes. | 24863413 |
| Hyperlipidemia, Inflammation, Each (qualifier value), Toxic effect | Altered Intercellular Communication | In zebrafish, EA-rHDL resulted in acute embryonic toxicity, and consumption of EA caused remarkable hyperlipidemia, inflammation, and fatty liver changes. | 24863413 |
| Restless Legs Syndrome | Altered Intercellular Communication | The scarcity of this alpha-synuclein gain-of-function variant in RLS might suggest that a low alpha-synuclein function via the SNARE complex in presynaptic vesicle release and neurotransmission of the striatum contributes to RLS pathogenesis. | 24863655 |
| Inflammation, Colorectal Carcinoma | Altered Intercellular Communication | Low-grade dietary-related inflammation and survival after colorectal cancer surgery. | 24863751 |
| Inflammation | Altered Intercellular Communication | Prolong inflammation is a central process observed in several chronic conditions and may be responsible for survival. | 24863751 |
| Inflammation | Altered Intercellular Communication | There is an increasing evidence showing the role of diet in inflammation and habitual diet may be responsible for low-grade inflammation. | 24863751 |
| Inflammation, Vasculitis, CTCAE, Systemic Vasculitis | Altered Intercellular Communication | Microscopic polyangiitis (MPA) is a systemic necrotizing vasculitis characterised by inflammation of the small blood vessels, the absence of granulommas on histopathological specimens, with few or no immune deposits and the presence of circulating anti-neutrophil cytoplasmic antibodies (ANCAs). | 24863847 |
| Chronic kidney disease stage 5, Kidney Failure, Chronic | Altered Intercellular Communication | Women with End Stage Renal Disease (ESRD) have hormonal imbalance leading to gynaecological and reproductive disturbances. | 24864612 |
| Inflammation | Altered Intercellular Communication | There was high prevalence of humoral immune alterations both in local and systemic response to chronic inflammation in the patients, which suggests that assessment of immunoglobulin before clinical evaluation and management could be important. | 24864628 |
| ARCN1 gene, Inflammation, Chronic Obstructive Airway Disease | Altered Intercellular Communication | Chronic inflammation of the lung is a characteristic finding in chronic obstructive pulmonary disease (COPD). | 24865134 |
| Eosinophilic inflammation | Altered Intercellular Communication | Macroscopic examination of the pleura showed diffuse thickening with pleural plaques in eight patients, consistent with diffuse pleural eosinophilic inflammation histologically proven. | 24865235 |
| Inflammation, Fibrosis Assessment, Tubular atrophy | Altered Intercellular Communication | The light microscopy study of the renal parenchyma in the MMA kidney revealed extensive interstitial fibrosis, chronic inflammation, and tubular atrophy. | 24865477 |
| Orbital Pseudotumor | Altered Intercellular Communication | Effect of hemodiafiltration with endogenous reinfusion on overt idiopathic chronic inflammation in maintenance hemodialysis patients: a multicenter longitudinal study. | 24865622 |
| Orbital Pseudotumor | Altered Intercellular Communication | These features could be helpful in MHD patients affected by idiopathic chronic inflammation, but this issue remains to be elucidated. | 24865622 |
| Inflammation, Orbital Pseudotumor | Altered Intercellular Communication | In MHD patients affected by idiopathic chronic inflammation the switching from BHD to HFR is associated with improvement of inflammation. | 24865622 |
| Inflammation, Immunodeficiency-Related Disorder | Altered Intercellular Communication | This is attributed to inflammation and immunodepression due to medications. | 24866077 |
| Parkinson Disease, Nail-Patella Syndrome, palladium | Altered Intercellular Communication | Neuropsychiatric symptoms (NPS) in Parkinson's disease (PD) have been mostly attributed to neurotransmitter imbalances. | 24866458 |
| Airway structure, Asthma | Altered Intercellular Communication | The CRTH2 antagonist OC000459 has previously been demonstrated to reduce airway inflammation and improve lung function in moderate persistent asthma. | 24866478 |
| Inflammation | Altered Intercellular Communication | Protein malnutrition was identified as an additional factor associated with retinal venular dilatation beyond inflammation. | 24867580 |
| Pain Distress Question, Inflammation, Fever, CTCAE, Kyphoscoliosis deformity of spine, Congenital Abnormality, Structure of pelvic girdle, Symptoms, Erythema, Hallux structure | Altered Intercellular Communication | The clinical symptoms include pain and inflammation of the soft tissue, sometimes associated with fever and cutaneous erythema, joint symptoms--pain, stiffness most frequently concerning the scapular and pelvic girdle, bone malformations--short hallux, microdactilia, kyphoscoliosis, thorax malformations. | 24868261 |
| ARCN1 gene, Inflammation | Altered Intercellular Communication | The 13 lipids with a high fold change between smokers with and without COPD showed high correlations with lower lung function and inflammation in sputum. | 24871890 |
| Airway structure, ARCN1 gene, Chronic Obstructive Airway Disease | Altered Intercellular Communication | There is an increased airway inflammation in the pathogenesis of chronic obstructive pulmonary disease (COPD), and it has been suggested that there may also be problem in the apoptosis and renewal of cells. | 24871992 |
| Inflammation, Granuloma | Altered Intercellular Communication | The pathological diagnoses of 14 false-positive cases by FDG-PET were chronic inflammation in 12 and non-specific granuloma in 2. | 24872477 |
| Inflammation, Infection | Altered Intercellular Communication | Cytokine production assays reveal discriminatory immune defects in adults with recurrent infections and noninfectious inflammation. | 24872512 |
| ARCN1 gene, Chronic Obstructive Airway Disease | Altered Intercellular Communication | Chronic neutrophilic inflammation is a hallmark in the pathogenesis of chronic obstructive pulmonary disease (COPD) and persists after cigarette smoking has stopped. | 24874071 |
| ARCN1 gene, Inflammation | Altered Intercellular Communication | We investigated changes to the leukotriene A4 hydrolase (LTA4H)-proline-glycine-proline (PGP) pathway and chronic inflammation in the development of COPD. | 24874071 |
| Inflammation, Pulmonary Emphysema | Altered Intercellular Communication | Mice exposed to cigarette smoke developed emphysema with increased PGP, neutrophilic inflammation, and selective inhibition of LTA4H aminopeptidase, which ordinarily degrades PGP. | 24874071 |
| Inflammation, Glaucoma, CTCAE, Ocular surface disease | Altered Intercellular Communication | Deep corneal vascularization (P = .012), preexisting active inflammation (P = .023), preexisting glaucoma drainage device (P = .023), and preexisting ocular surface disease (P = .037) were associated with reduced graft survival in a univariate analysis. | 24875001 |
| vascular inflammations | Altered Intercellular Communication | Estrogen effects on vascular inflammation are age dependent: role of estrogen receptors. | 24876352 |
| vascular inflammations | Altered Intercellular Communication | We hypothesize that E2 effects on vascular inflammation are age dependent. | 24876352 |
| Inflammation, Amyloidosis | Altered Intercellular Communication | Amyloidosis, inflammation, and oxidative stress in the heart of an alkaptonuric patient. | 24876668 |
| Inflammation | Altered Intercellular Communication | Immunofluorescence detected lipid peroxidation of the tissue and lymphocyte/macrophage infiltration causing inflammation. | 24876668 |
| Autoimmune Diseases, Inflammation, Acute myocardial infarction, Ischemic stroke | Altered Intercellular Communication | Autoimmune rheumatic diseases (ARD) are characterized by systemic inflammation and may affect multiple organs and cause vascular events such as ischemic stroke and acute myocardial infarction. | 24877143 |
| Inflammation, Fibrosis Assessment, Coronary Arteriosclerosis | Altered Intercellular Communication | The inflammation and fibrosis, in combination with concomitant atherosclerotic disease, resulted in severe stenosis of the coronary arteries. | 24878025 |
| Airway structure | Altered Intercellular Communication | However, the effect of ambient metals exposure on airway inflammation, and how these associations may be modified by seroatopy, has not been determined. | 24878380 |
| Airway structure | Altered Intercellular Communication | Fractional exhaled nitric oxide (FENO) is a reliable proxy marker of airway inflammation. | 24878380 |
| Communicable Diseases, Inflammation, HIV Infections, GRN wt Allele | Altered Intercellular Communication | PGRN production is also modulated by inflammation and infection, but no data are available on the production and role of PGRN during CNS HIV infection. | 24878635 |
| Inflammation, HIV Infections, GRN wt Allele | Altered Intercellular Communication | To determine the relationships between PGRN and HIV disease, neurocognition, and inflammation, we analyzed 107 matched CSF and plasma samples from CHARTER, a well-characterized HIV cohort. | 24878635 |
| Inflammation, Malnutrition | Altered Intercellular Communication | Free triiodothyronine in hemodialysis patients: link with malnutrition and inflammation. | 24878944 |
| Inflammation, Malnutrition | Altered Intercellular Communication | There is lack of data about the link between FT3 levels and malnutrition and inflammation in hemodialysis patients. | 24878944 |
| Comorbidity | Altered Intercellular Communication | Patients' comorbidity status was determined using the Charlson Comorbidity Index (CCI), and malnutrition-inflammation status was determined by Malnutrition-Inflammation Score (MIS). | 24878944 |
| Inflammation, Appendicitis, CTCAE | Altered Intercellular Communication | Of the 199 procedures, 4 appendectomies were negative (histologically normal), 182 were positive (primary appendicitis) and 13 were incidental (another primary process caused inflammation). | 24879063 |
| Tubulitis Assessment, Interstitial inflammation, Glomerulitis (disorder) | Altered Intercellular Communication | On 1-year protocol biopsies, the dnDSA group showed more interstitial inflammation, tubulitis, and glomerulitis. | 24879384 |
| Inflammation, Vasculitis, CTCAE | Altered Intercellular Communication | In addition, 1 biopsy had lichenoid inflammation in the epidermis and the other had evidence of vasculitis. | 24879511 |
| Musculoskeletal Pain, Muscular stiffness, Ache | Altered Intercellular Communication | Polymyalgia rheumatica (PMR) is an idiopathic systemic inflammatory condition manifesting as aches and muscle stiffness of the proximal muscle groups. | 24879730 |
| Inflammation | Altered Intercellular Communication | Localization of PC (16:0/16:0) might reflect inflammation activity participating in the pathogenesis of War-T. | 24880872 |
| Airway structure, Acute asthma | Altered Intercellular Communication | A human monoclonal anti-TNF alpha antibody (adalimumab) reduces airway inflammation and ameliorates lung histology in a murine model of acute asthma. | 24882395 |
| Alveolus, Inflammation | Altered Intercellular Communication | Lung parenchyma, alveolus, peribronchial and perivascular inflammation were assessed. | 24882395 |
| Inflammation, Chronic purulent otitis media | Altered Intercellular Communication | Mucosae from the CSOM group presented chronic inflammation or suppurative inflammation in the rudimentary stroma, mainly with infiltration of monocytes and macrophages. | 24882571 |
| Inflammation, Chronic purulent otitis media | Altered Intercellular Communication | Reduced TLR levels in the middle-ear mucosa might cause weak host response to bacteria, persistent inflammation and susceptibility to CSOM. | 24882571 |
| Inflammation, Manufactured sign | Altered Intercellular Communication | Records from 181 patients with ocular signs and symptoms suggestive of TRU and intraocular inflammation of unknown etiology were reviewed. | 24882956 |
| Intraocular inflammation, Retinal Vasculitis, Uveitis | Altered Intercellular Communication | The positive predictive value of the IGRA among patients with intraocular inflammation was high (70%) when all of younger age (<= 40 years), posterior uveitis, and retinal vasculitis were present. | 24882956 |
| Acquired Immunodeficiency Syndrome, Myositis, Muscular Atrophy, Malignant Neoplasms, Chronic disease | Altered Intercellular Communication | Muscle wasting is frequently a result of cancers, AIDS, chronic diseases and aging, which often links to muscle inflammation. | 24884473 |
| Muscular Atrophy, Chronic inflammation, Muscle (organ) | Altered Intercellular Communication | GSE supplementation effectively prevents muscle wasting in IL10KO mice, showing that GSE can be used as an auxiliary treatment for muscle loss associated with chronic inflammation and frailty. | 24884473 |
| Refractory anemias, Autoimmune Diseases, Synovial joint structure, Rheumatoid Arthritis, Chronic destructive inflammation | Altered Intercellular Communication | Rheumatoid arthritis (RA) is a systemic autoimmune disease characterized by chronic destructive inflammation in synovial joints. | 24884566 |
| Retinal Vein Occlusion, Inflammation, Edema | Altered Intercellular Communication | Role of inflammation in previously untreated macular edema with branch retinal vein occlusion. | 24884703 |
| Inflammation, Edema | Altered Intercellular Communication | The relationship between the aqueous flare value and the vitreous fluid levels of vascular endothelial growth factor (VEGF), interleukin (IL)-6, monocyte chemotactic protein (MCP)-1, soluble intercellular adhesion molecule 1 (sICAM-1), and soluble VEGF receptor-2 (sVEGFR-2) was evaluated to investigate the role of inflammation in BRVO associated with macular edema. | 24884703 |
| Inflammation, Macular retinal edema | Altered Intercellular Communication | Inflammation may induce an increase of vascular permeability and disrupt the blood-aqueous barrier via release of inflammatory factors (VEGF, IL-6, MCP-1, and sICAM-1) in BRVO patients with macular edema. | 24884703 |
| Inflammation, Diabetes Mellitus, Non-Insulin-Dependent | Altered Intercellular Communication | A disadvantaged social position in childhood, as measured by father's manual occupation, was associated at conventional levels of statistical significance with an increased risk of type 2 diabetes in adulthood, both directly and indirectly through inflammation, adulthood social position and a risk score constructed from adult health behaviours including tobacco smoking and limited physical activity. | 24884735 |
| ARCN1 gene, Inflammation, Chronic Obstructive Airway Disease | Altered Intercellular Communication | At the present stage of study of chronic obstructive pulmonary disease (COPD) one of the problem is the definition of new criteria for the topical and systemic chronic inflammation of this disease. | 24884928 |
| Amyotrophic Lateral Sclerosis, Neurodegenerative Disorders, Inflammation | Altered Intercellular Communication | The involvement of inflammation in the pathogenesis of neurodegenerative diseases, including ALS, is increasingly recognized but still not well understood. | 24884937 |
| Inflammation, Fever, CTCAE | Altered Intercellular Communication | Antibiotic treatment reduced humoral inflammation, but failed to resolve her fever. | 24885004 |
| Immobile, Endocrine System Diseases, Chronic disease, Osteoporosis | Altered Intercellular Communication | Etiological factors responsible for osteoporosis secondary to chronic illness include immobility, pubertal delay and other hormonal disturbances. | 24885558 |
| Gestational Diabetes, Inflammation | Altered Intercellular Communication | Integrative analysis of the transcriptome profiles observed in type 1, type 2 and gestational diabetes mellitus reveals the role of inflammation. | 24885568 |
| Gestational Diabetes, Inflammation, Choroidal and Ciliary Body Melanoma pT1d TNM Finding v8 | Altered Intercellular Communication | The functional analyses were able to discriminate between T1D and GDM patients based on genes involved in inflammation. | 24885568 |
| Inflammation, Bronchial Hyperreactivity, Familial Hypophosphatemic Rickets | Altered Intercellular Communication | A mutated vitamin D receptor in hereditary vitamin D-resistant rickets prevents induction of bronchial hyperreactivity and inflammation. | 24885630 |
| Inflammation, Familial Hypophosphatemic Rickets, Allergy - Charge Type Reason | Altered Intercellular Communication | The aim of the study was to determine the role of the VDR on lung functions, airways, and systemic markers of inflammation and allergy in HVDRR patients. | 24885630 |
| Inflammation | Altered Intercellular Communication | In this case, increased (18) F-FDG uptake is more likely to appear, particularly if the inflammation is predominant. | 24885757 |
| Pneumonitis | Altered Intercellular Communication | Altogether, the data reported here strongly suggest that welding-related NP could be responsible, at least in part, for the pulmonary inflammation observed in welders. | 24885771 |
| Neoplasm Metastasis | Altered Intercellular Communication | For shorter OS, synchronous metastasis (HR 3.05, 95% CI 1.07-11.94, p = 0.048) and inflammation-based prognostic score (HR 6.65, 95% CI 1.25-35.23, p = 0.026) were identified as independent prognostic factors. | 24885814 |
| Neurodegenerative Disorders, Inflammation, Cardiovascular Diseases, Diabetes Mellitus, Transient Ischemic Attack | Altered Intercellular Communication | The same biological responses thought to effect cardiovascular disease through air pollution-mediated systemic oxidative stress, inflammation and cerebrovascular dysfunction could also be relevant for diabetes and neurodegenerative diseases. | 24886318 |
| Inflammation, Arthritis, Gouty, Collagen Diseases | Altered Intercellular Communication | This study investigates the impact of serum uric acid, inflammation and traditional CV risk parameters on CV event risk in patients with gouty arthritis and patients with non-gouty rheumatic disease. | 24886363 |
| ARCN1 gene, Inflammation, Bronchiectasis, Airway structure, Bacterial Infections, Damage | Altered Intercellular Communication | In contrast to other chronic airway infections, associated with COPD and CF bronchiectasis, where polymicrobial communities have been implicated in lung damage due to the vicious circle of recurrent bacterial infections and inflammation, there is sparse information on the composition of bacterial communities in NCFBr. | 24886473 |
| Vascular Diseases, Inflammation, Atherosclerosis | Altered Intercellular Communication | If endothelial cells are excessively activated, it may lead to vasculopathic diseases, such as pathologic angiogenesis, inflammation, and atherosclerosis. | 24886494 |
| Inflammation, bone destruction, Synovitis | Altered Intercellular Communication | For example, MCP-1 and IL-6 were associated with both general inflammation and bone destruction, in contrast to MIP-1b, which was involved solely in general synovitis. | 24886513 |
| Myositis | Altered Intercellular Communication | To explore this hypothesis we compared IMAT and muscular inflammation in age-and BMI-matched older non-obese frail and non-frail adults. | 24886741 |
| Myositis | Altered Intercellular Communication | Non-obese, older, frail individuals have increased IMAT and muscular inflammation when compared to their non-frail, age- and BMI-matched peers. | 24886741 |
| Inflammation, Fibrosis Assessment, Necrosis | Altered Intercellular Communication | Biopsies were scored for presence of inflammation, necrotic muscle fibers, rimmed vacuoles, fibrosis, and immunohistochemical staining. | 24886750 |
| Inflammation | Altered Intercellular Communication | In addition, we found that necrotizing muscle fibers with inflammation characterize SSc-PM overlap in muscle biopsies. | 24886750 |
| Inflammation, Fibrosis Assessment, Necrosis | Altered Intercellular Communication | Further research should focus on underlying mechanisms causing necrosis, inflammation, and fibrosis and their relation to pulmonary involvement and mortality in patients with SSc-PM overlap. | 24886750 |
| Delirium, Critical Illness | Altered Intercellular Communication | Inflammation biomarkers and delirium in critically ill patients. | 24886875 |
| Delirium, Inflammation, Critical Illness, septic | Altered Intercellular Communication | The aim of this investigation was to study the relationship between systemic inflammation and the development of delirium in septic and non-septic critically ill patients. | 24886875 |
| Inflammation, Hemorrhage, Edema | Altered Intercellular Communication | Hemorrhages, vessel fibrinoid necrosis, perivascular fibrin exudation, edema and neutrophilic inflammation are early features, while perivascular demyelination, microglial foci and myelin-laden macrophages appear later. | 24887055 |
| Inflammation, Hemorrhage, Edema | Altered Intercellular Communication | Severe hemorrhages, edema and neutrophilic inflammation in the absence of circumscribed perivascular demyelination affected the temporal neocortex and white matter, hippocampus, cerebellar cortex and white matter, optic chiasm, mammillary bodies, brainstem, cranial nerve roots and leptomeninges. | 24887055 |
| Loss of myelin, Inflammation, Damage, MS gene | Altered Intercellular Communication | Inflammation and complement activation are firmly implicated in the pathology of multiple sclerosis; however, the extent and nature of their involvement in specific pathological processes such as axonal damage, myelin loss and disease progression remains uncertain. | 24887075 |
| Inflammation, Chronic active | Altered Intercellular Communication | Active, chronic active and chronic inactive multiple sclerosis plaques (35 in total) and non-plaque areas were examined.Multiple sclerosis plaques were consistently positive for complement proteins (C3, factor B, C1q), activation products (C3b, iC3b, C4d, terminal complement complex) and regulators (factor H, C1-inhibitor, clusterin), suggesting continuing local complement synthesis, activation and regulation despite the absence of other evidence of ongoing inflammation. | 24887075 |
| Inflammation, Hypoxia | Altered Intercellular Communication | The finding that the human carotid body releases cytokines in response to hypoxia adds to the growing body of information suggesting that the carotid body may play a role in detecting inflammation, providing a link between the immune system and the nervous system. | 24887113 |
| Hypoxemia, Pneumonitis | Altered Intercellular Communication | Furthermore, S100A12 levels were associated with increased levels of markers of pulmonary inflammation, prolonged cardiopulmonary bypass, hypoxemia and duration of mechanical ventilation. | 24887223 |
| Acute Lung Injury, Hypoxia, Pneumonitis | Altered Intercellular Communication | S100A12 is associated with duration of cardiopulmonary bypass, pulmonary inflammation, hypoxia and prolonged mechanical ventilation and may contribute to acute lung injury in cardiac surgery patients. | 24887223 |
| Proteinuria, Inflammation, Adult Non-Hodgkin Lymphoma | Altered Intercellular Communication | Proteinuria is a simple sign of systemic inflammation that leads to a poor prognosis in individuals affected with non-Hodgkin lymphoma. | 24887301 |
| Proteinuria, Inflammation, RTEL1 gene | Altered Intercellular Communication | Proteinuria is a simple sign of coexisting systemic inflammation due to NHL and a harbinger of a poor prognosis. | 24887301 |
| Inflammation, Pneumonia, Parkinson Disease, palladium, Delirium, Respiratory Tract Infections | Altered Intercellular Communication | In Parkinson disease (PD), systemic inflammation caused by respiratory infections such as pneumonia frequently occurs, often resulting in delirium in the advanced stages of this disease. | 24887491 |
| Symptoms, Inflammation | Altered Intercellular Communication | Inflammation causes rapid worsening of PD motor symptoms and signs, sometimes irreversibly in some, but not all, patients. | 24887491 |
| palladium, Inflammation | Altered Intercellular Communication | To identify factors associated with subacute motor deterioration in PD patients with systemic inflammation. | 24887491 |
| palladium, Inflammation, Motor deterioration | Altered Intercellular Communication | Of 80 PD patients with systemic inflammation, 26 with associated subacute motor deterioration were designated as cases and the remainder as controls. | 24887491 |
| Delirium, Inflammation, Motor deterioration | Altered Intercellular Communication | Multivariable logistic regression analysis showed that delirium and body temperature are significantly associated with motor deterioration after systemic inflammation (P = 0.001 for delirium and P = 0.026 for body temperature), the adjusted odds ratios being 15.89 (95% confidence interval [CI]: 3.23-78.14) and 2.78 (95% CI: 1.13-6.83), respectively. | 24887491 |
| palladium, Inflammation, Delirium, Motor deterioration | Altered Intercellular Communication | In patients with PD and systemic inflammation, delirium and high body temperature are strong risk factors for subsequent subacute motor deterioration and such deterioration can persist for over 6 months. | 24887491 |
| Inflammation, Hemorrhage, Obstruction, Perforation (observation) | Altered Intercellular Communication | Complications were defined as those that presented with inflammation, bleeding, obstruction, or perforation. | 24887799 |
| Inflammation, Hemorrhage, Cerebrovascular accident | Altered Intercellular Communication | Late diagnosis resulted in severe hemorrhage and postoperative cerebrovascular accident because of the impossibility of repairing the carotid artery due to severe local inflammation. | 24887873 |
| Communicable Diseases, Inflammation, Pneumonia | Altered Intercellular Communication | Pneumonia is a disease causing serious inflammation and infection of the lungs and accounts for >50,000 mortalities annually. | 24888337 |
| Inflammation, Pneumonia, Community acquired pneumonia | Altered Intercellular Communication | Pneumonia is more serious in the elderly than in any other age group due to the increased inflammation and risk of community-acquired pneumonia associated with aging. | 24888337 |
| NCI CTEP SDC Myelodysplastic Syndrome Sub-Category Terminology, Inflammation, Anemia, Miller Dieker syndrome | Altered Intercellular Communication | Interleukin-6 (IL-6) may play an important role in the pathophysiology of anemia of inflammation associated with myelodysplastic syndrome (MDS). | 24888488 |
| Extrinsic allergic alveolitis, Bronchitis | Altered Intercellular Communication | Bronchial inflammation in hypersensitivity pneumonitis after antigen-specific inhalation challenge. | 24890329 |
| Bronchitis | Altered Intercellular Communication | This study shows that bronchial inflammation is present in patients with HP evidenced by increases in sputum neutrophils and eosinophils following exposure to the offending antigen during SIC. | 24890329 |
| Waldenstrom Macroglobulinemia | Altered Intercellular Communication | Mild lymphoplasmacytic inflammation and few scattered lymphoid aggregates were present, but we found no pathognomonic histopathologic features of anti-EJ ARS syndrome. | 24891607 |
| ARCN1 gene, Inflammation, Chronic Obstructive Airway Disease, Lung diseases | Altered Intercellular Communication | COPD (chronic obstructive pulmonary disease) is a common lung disease characterized by airflow limitation and systemic inflammation. | 24891763 |
| Inflammation | Altered Intercellular Communication | Recently, adipose tissue mediated inflammation has gathered increasing interest in the pathogenesis of the disease. | 24891763 |
| ARCN1 gene, Inflammation | Altered Intercellular Communication | The present results introduce adipocytokines NUCB2/nesfatin-1 and visfatin as novel factors associated with systemic inflammation in COPD and suggest that visfatin may mediate impaired pulmonary diffusing capacity. | 24891763 |
| Inflammation, Orbital Cellulitis | Altered Intercellular Communication | Dacryops infection is a rare but important consideration in the differential of a mass lesion in the upper fornix associated with inflammation that may be confused with orbital cellulitis or abscess. | 24892277 |
| Inflammation, Infiltration, Edema | Altered Intercellular Communication | Electron microscopic features include blunted epithelial microvilli, numerous fibroblasts, extensive and irregularly arranged collagen bundles, mononuclear infiltration in the vicinity of fibroblasts or in between collagen bundles, and inter- and intracellular edema in areas of inflammation. | 24892278 |
| Inflammation, Fibrosis Assessment | Altered Intercellular Communication | Chronic inflammation and subsequent fibrosis appear to be the basic ultrastructural response to various noxious stimuli. | 24892278 |
| Perimenopausal state, Inflammation, Depression, CTCAE | Altered Intercellular Communication | This negative finding in perimenopausal depression indicates either the absence or a more complex nature of the interactions between acute-phase proteins, low-grade inflammation and depression. | 24894416 |
| Inflammation, Asthma | Altered Intercellular Communication | Inflammation in the small airways might contribute to incomplete asthma disease control despite intensive treatment in some subgroups of patients. | 24894594 |
| Inflammation, Asthma | Altered Intercellular Communication | Exhaled NO (FeNO) is a marker of inflammation in asthma and the estimated NO contribution from small airways (CalvNO ) is believed to reflect distal inflammation. | 24894594 |
| Myositis, CTCAE 5.0, Pneumonitis | Altered Intercellular Communication | A positive association was found between HLA-DQA1*0104 and DM (p = 0.01; corrected p (pcorr) NS; odds ratio (OR) = 2.58; 95% confidence interval (CI): 1.18-5.64), while an inverse correlation was noted between HLA-DQB1*0303 and myositis patients with interstitial lung inflammation (p = 0.01; pcorr NS; OR = 0.25; 95% CI: 0.07-0.73). | 24894810 |
| Inflammation, Jaw claudication | Altered Intercellular Communication | Jaw claudication correlated moderately with inflammation of the temporalis muscle (r = 0.31; p < 0.05) and the deep temporal artery (r = 0.38; p = 0.01). | 24895039 |
| Myositis | Altered Intercellular Communication | * Approximately 20 % of GCA patients presented with temporalis muscle inflammation. | 24895039 |
| Vasculitis, CTCAE, Myositis | Altered Intercellular Communication | * MRI is a suitable tool for the assessment of vasculitis and muscle inflammation. | 24895039 |
| Inflammation | Altered Intercellular Communication | These findings suggest a protective role of DC in post-MI inflammation and the subsequent healing process. | 24895162 |
| Inflammation, Fibrosis Assessment, Graves Disease | Altered Intercellular Communication | Histopathological analysis revealed chronic inflammation and fibrosis consistent with Graves disease. | 24896772 |
| Immediate hypersensitivity | Altered Intercellular Communication | Our results indicate that secondary allergen-specific IgE production and IgE-mediated allergic inflammation do not require a fully functional CD4+ T lymphocyte repertoire. | 24896832 |
| Inflammation, Squamous cell carcinoma of esophagus | Altered Intercellular Communication | Our results suggested that whole genome hypomethylation caused by chronic inflammation could initiate carcinogenesis of esophageal squamous cells through chromosomal instability. | 24898425 |
| Inflammation, Deep Vein Thrombosis, Venous Insufficiency | Altered Intercellular Communication | Inflammation may also be involved in venous insufficiency apart from deep-vein thrombosis. | 24898679 |
| Inflammation, Venous Insufficiency | Altered Intercellular Communication | We studied the association of inflammation markers with venous insufficiency in a general population sample. | 24898679 |
| Disorder of vein, Congenital Abnormality | Altered Intercellular Communication | Inflammation markers, C-reactive protein (CRP), fibrinogen, interleukin 1-beta (IL-1-beta), IL-8, IL-10, intercellular adhesion molecule-1 (ICAM-1), vascular cell adhesion molecule-1 (VCAM-1), E-selectin, monocyte chemoattractant-1 (MCP-1) and vascular endothelial cell growth factor (VEGF) were compared in 352 case participants with peripheral venous disease and 352 controls with no venous abnormalities frequency matched to cases by age, sex and race. | 24898679 |
| Disorder of vein, Inflammation | Altered Intercellular Communication | In conclusion, a subset of inflammation markers were associated with increased risk of peripheral venous disease, suggesting potential therapeutic targets for treatment. | 24898679 |
| Cerebrovascular accident | Altered Intercellular Communication | Our results strongly suggest that the abnormal expression of CD137L on monocytes may lead to dyregulated CD137L/CD137 signaling and consequently form part of a positive-feedback, inflammation-promoting circuit in stroke, while the elevated sCD137L protein levels may function as a self-regulatory mechanism of CD137/CD137L interaction and costimulation. | 24899613 |
| Inflammation | Altered Intercellular Communication | At low concentrations, oxypurinol should reduce inflammation, but high concentrations may contribute to oxidative stress. | 24899662 |
| Inflammation, Demyelination, Nerve Degeneration | Altered Intercellular Communication | Multiple sclerosis deep grey matter: the relation between demyelination, neurodegeneration, inflammation and iron. | 24899728 |
| Diffuse Axonal Injury, Inflammation | Altered Intercellular Communication | In addition, detailed analyses of inflammation, acute axonal injury, iron deposition and oxidative stress were performed. | 24899728 |
| Cerebral cortex | Altered Intercellular Communication | Deep grey matter inflammation was intermediate between low inflammatory cortical lesions and active white matter lesions. | 24899728 |
| Malignant - descriptor, Inflammation | Altered Intercellular Communication | However, in cases with more pronounced inflammation during treatment, targeted biopsies indicated very early malignant alterations. | 24900953 |
| Inflammation, Fibrosis Assessment | Altered Intercellular Communication | Our dedicated pathologist designed a score to quantify fibrosis and inflammation of pancreatic tissue. | 24900974 |
| Inflammation | Altered Intercellular Communication | Systemic low-grade inflammation may contribute to elevated serum Cu and decreased serum Zn concentrations in the elderly, and may represent an important confounder of the relationship between the serum trace elements and mortality in this population. | 24901093 |
| Acute inflammation | Altered Intercellular Communication | Laparoscopic surgery may decrease the risk of postoperative abdominal adhesion compared with open surgery by suppressing early postoperative inflammation. | 24901144 |
| Inflammation, Stomach Carcinoma, Infection caused by Helicobacter pylori | Altered Intercellular Communication | As chronic inflammation of the gastric mucosa is a consequence of Helicobacter pylori infection, we investigated the role of genetic polymorphisms and expression of genes involved in the NLR signalling pathway in H. pylori infection and related gastric cancer (GC). | 24901306 |
| Choroiditis | Altered Intercellular Communication | Thicker CT 1 week postoperatively after SBS may most likely be induced by scleral buckle reduced blood flow and increased haemostasis in the choroidal circulation and by scleral and choroidal inflammation after cryopexy versus laser photocoagulation after SBS versus PPV. | 24901425 |
| Inflammation | Altered Intercellular Communication | Circulating levels of IL-18, and other biochemical markers are parameters of inflammation and were measured in all three groups. | 24901579 |
| Inflammation, Calcinosis | Altered Intercellular Communication | Calcification and inflammation are among the important cases of exudative age-related macular degeneration (E-ARMD). | 24901855 |
| Inflammation, Pulmonary Emphysema | Altered Intercellular Communication | OPN may play a role in the neutrophilic inflammation and in the pathogenesis of emphysema. | 24902063 |
| Inflammation, Atrophic | Altered Intercellular Communication | Chronic inflammation was present only in complete atrophy. | 24902359 |
| Inflammation, Atrophic | Altered Intercellular Communication | Chronic inflammation may be a secondary phenomenon seen only in complete atrophy. | 24902359 |
| Weight decreased | Altered Intercellular Communication | Along with weight loss itself, changes in gut hormone profiles after surgery play an important role in the amelioration of glycemic control. | 24902653 |
| Autoimmune Diseases, Inflammation, Lupus Erythematosus, Lupus Erythematosus, Systemic | Altered Intercellular Communication | While the specific role of PMN in systemic lupus erythematosus (SLE) and autoimmunity is still unclear, their importance in chronic inflammation is gaining more attention. | 24902963 |
| Inflammation, Inflammatory disorder | Altered Intercellular Communication | Recently, PG and SS have been included among the autoinflammatory diseases, which are characterized by recurrent episodes of sterile inflammation, without circulating autoantibodies and autoreactive T cells. | 24903614 |
| Tissue damage, Inflammation | Altered Intercellular Communication | Fas/Fas ligand and CD40/CD40 ligand systems were over-expressed in PG (P = 0*0001 for Fas, P = 0*009 for Fas ligand, P = 0*012 for CD40, P = 0*0001 for CD40 ligand), contributing to tissue damage and inflammation, while their role seems to be less significant in SS. | 24903614 |
| Inflammation, Ischemic stroke | Altered Intercellular Communication | The changes of bilirubin and liver enzymes during ischemic stroke reflect two phenomena, which are both related to IV: 1) inflammation, with consequent increment of CRP, leukocytes and gGT, and decrease of haemoglobin and unconjugated bilirubin and 2) an unknown signal, independent from inflammation, leading to increasing GOT and GPT levels. | 24903748 |
| Hyperlipidemia, Inflammation, Diabetes Mellitus, Heart Diseases, Hypertension, CTCAE | Altered Intercellular Communication | Hypertension, hyperlipidemia, diabetes, cardiac diseases, inflammation, and smoking were recorded. | 24904181 |
| Non-alcoholic Fatty Liver Disease, Arteritis | Altered Intercellular Communication | Association between nonalcoholic fatty liver disease and carotid artery inflammation evaluated by 18F-fluorodeoxyglucose positron emission tomography. | 24904182 |
| Non-alcoholic Fatty Liver Disease, Arteritis | Altered Intercellular Communication | We assessed the association between nonalcoholic fatty liver disease (NAFLD) and carotid artery inflammation measured by (18)F-fluorodeoxyglucose (FDG) positron emission tomography/computed tomography. | 24904182 |
| Inflammation, Haiti | Altered Intercellular Communication | Higher nBsAb levels were found to be associated with decreased inflammation in HT patients. | 24905062 |
| Inflammation, Coronary Artery Disease, Endothelial dysfunction, Diabetes Mellitus | Altered Intercellular Communication | Orosomucoid secretion levels by epicardial adipose tissue as possible indicator of endothelial dysfunction in diabetes mellitus or inflammation in coronary artery disease. | 24905138 |
| Inflammation, Fibrosis Assessment, Atrophic | Altered Intercellular Communication | The glands were routinely processed and semi-quantitatively analyzed for inflammation, acinar atrophy, fibrosis, and adipocyte infiltration. | 24905142 |
| Inflammation, Fibrosis Assessment, Atrophic | Altered Intercellular Communication | Acinar atrophy and fibrosis were negatively correlated with the parenchymal innervation and positively related to diffuse inflammation. | 24905142 |
| Inflammation, Endothelium, Psoriasis, Atherosclerosis | Altered Intercellular Communication | Systemic inflammation and imbalance between endothelial injury and repair in patients with psoriasis are associated with preclinical atherosclerosis. | 24906366 |
| Valvular regurgitation, Inflammation, Endothelium, Atherosclerosis | Altered Intercellular Communication | Systemic inflammation and imbalance between endothelial injury and repair, the latter referred to as vascular incompetence, are associated with atherosclerosis and cardiovascular risk. | 24906366 |
| Inflammation, Psoriasis, Carotid Intima-Media Thickness, Metabolic Syndrome X, Valvular regurgitation | Altered Intercellular Communication | We investigated whether, in psoriasis, inflammation and vascular incompetence are associated with carotid intima-media thickness (cIMT) irrespective of metabolic syndrome and other established cardiovascular risk factors. | 24906366 |
| Valvular regurgitation, Inflammation, Psoriasis, Atherosclerosis | Altered Intercellular Communication | Patients with psoriasis have an increased burden of cardiovascular risk, including inflammation, vascular incompetence and early atherosclerosis. | 24906366 |
| HD Term Type, Inflammation | Altered Intercellular Communication | The present study indicates that serum CRP and sICAM-1, as two CVD risk factors, increase in HD patients with PEW as compared to those without PEW and these increases occur in HD patients with PEW type IIa and IIb who have inflammation. | 24906424 |
| Inflammation, Edema | Altered Intercellular Communication | after the stage compromised by acute oedema and inflammation. | 24906703 |
| Sarcoidosis, Lymphoid hyperplasia, Lymphoma, Orbital Pseudotumor | Altered Intercellular Communication | The most common diagnoses included idiopathic orbital inflammation (IOI; n = 29; 30%), sarcoidosis (n = 19; 20%), prolapsed LG (n = 15; 15%), lymphoma (n = 11; 11%), lymphoid hyperplasia (n = 8; 8%), and dacryops (n = 5; 5%). | 24907059 |
| Pain Distress Question, Inflammation, Blepharoptosis | Altered Intercellular Communication | Inflammatory conditions were more likely in younger patients (P<0.05) and in those with pain (P<0.001) and mechanical blepharoptosis (P<0.01) at presentation, whereas lymphoma was more common in older patients (P<0.001) without active signs of inflammation at presentation. | 24907059 |
| Pain Distress Question, Inflammation, Blepharoptosis | Altered Intercellular Communication | Inflammatory conditions were more likely in younger patients (P<0.05) and in those with pain (P<0.001) and mechanical blepharoptosis (P<0.01) at presentation, whereas lymphoma was more common in older patients (P<0.001) without active signs of inflammation at presentation. | 24907059 |
| Inflammation, Macular retinal edema | Altered Intercellular Communication | Dexamethasone intravitreal implant in the treatment of persistent uveitic macular edema in the absence of active inflammation. | 24907061 |
| Adenocarcinoma, Inflammation, Mesothelioma | Altered Intercellular Communication | The definitive diagnoses were adenocarcinoma (n = 10), mesothelioma (n = 2) and chronic inflammation (n = 3). | 24907385 |
| Inflammation, Pain Distress Question | Altered Intercellular Communication | Inflammation and inflammatory control in interstitial cystitis/bladder pain syndrome: Associations with painful symptoms. | 24907404 |
| Inflammation, Genitourinary pain, Sex Behavior | Altered Intercellular Communication | In IC/BPS patients, inflammation after TLR-4 stimulation was associated with multiple symptoms, including genitourinary pain (P=.010), sexual pain (P=.002), and marginally with urinary symptoms (P=.068). | 24907404 |
| Inflammatory abnormality of the eye | Altered Intercellular Communication | Drug-related adverse events were reported by 13 (41%) of 32 patients; they included ocular inflammation in 11 patients (7 mild, 4 moderate in severity). | 24907435 |
| Inflammatory abnormality of the eye | Altered Intercellular Communication | A single injection of 1.0 or 2.0 mg MP0112 resulted in mean decreases in retinal thickness and leakage area despite ocular inflammation. | 24907435 |
| Inflammation | Altered Intercellular Communication | Flow cytometry-based analysis by Sysmex-UF1000i(r) is an alternative method in the assessment of periodontal inflammation. | 24907666 |
| Inflammation | Altered Intercellular Communication | We explored the value of flow cytometry of saliva in patients with periodontal inflammation. | 24907666 |
| Inflammation, Coronary Arteriosclerosis | Altered Intercellular Communication | Our results support the hypothesis that air pollution increases systemic inflammation especially in susceptible populations which may aggravate atherosclerotic diseases and induce multi-organ damage. | 24907704 |
| Inflammation, "Alzheimers Disease", Data types - Address | Altered Intercellular Communication | Inflammation is a hallmark of Alzheimer's disease (AD). | 24907904 |
| hydrocortisone, Inflammation, Data types - Address | Altered Intercellular Communication | Despite inflammation being a hallmark in AD and previous reports showing that the NLR can discriminate HC from AD patients, our results suggest that the sensitivity of the NLR itself is not robust enough for diagnostic utility. | 24907904 |
| Inflammation, Respiratory Hypersensitivity | Altered Intercellular Communication | Previously, we showed that, in ovalbumin (OVA)-sensitized and -challenged mice with allergic airway inflammation, rhinovirus (RV) infection increases type 2 cytokine production from alternatively-activated (M2) airway macrophages, enhancing eosinophilic inflammation and airways hyperresponsiveness. | 24907978 |
| Airway structure, neutrophilic, Inflammation | Altered Intercellular Communication | In contrast to OVA-treated wild-type mice with both neutrophilic and eosinophilic airway inflammation, OVA-treated IL-4R KO mice showed increased neutrophilic inflammation with few eosinophils in the airways. | 24907978 |
| Inflammation, Residual volume | Altered Intercellular Communication | RV infection of OVA-treated IL-4R KO mice further increased neutrophilic inflammation. | 24907978 |
| Airway structure, Allergic | Altered Intercellular Communication | OVA-treated IL-4R KO mice show neutrophilic airway inflammation constituting a model of allergic, type 1 cytokine-driven neutrophilic asthma. | 24907978 |
| Inflammation, Residual volume | Altered Intercellular Communication | In the absence of IL-4/IL-13 signaling, RV infection of OVA-treated mice increased type 1 cytokine and IL-17A production from conventionally-activated macrophages, augmenting neutrophilic rather than eosinophilic inflammation. | 24907978 |
| Residual volume | Altered Intercellular Communication | In mice with allergic airways inflammation, IL-4R signaling determines macrophage activation state and the response to subsequent RV infection. | 24907978 |
| Inflammation, Carcinoma of bladder | Altered Intercellular Communication | Of 12 (18)F-FDG-avid cases, 10 cases were confirmed to be primary bladder carcinoma, 2 false-positive cases were inflammation. | 24908368 |
| Inflammation, Psoriasis, Chronic disease | Altered Intercellular Communication | Psoriasis is a common chronic disease, mediated by type 1 and 17 helper T cell-driven inflammation. | 24909271 |
| Inflammation, Depression, CTCAE | Altered Intercellular Communication | Literature on the relationship between depression and C-reactive protein (CRP), a biomarker of systematic inflammation, remains inconsistent. | 24909972 |
| Inflammation, Data types - Address | Altered Intercellular Communication | This study supports the role of infection/inflammation in the etiopathogenesis of AD. | 24910016 |
| Inflammation, Cytomegalovirus, Perforation (observation) | Altered Intercellular Communication | Pathologic examination of the resected appendiceal tissue demonstrated inflammation with perforation and cytopathic changes typical of CMV that were positive for CMV by immunostain. | 24910267 |
| Inflammation | Altered Intercellular Communication | Differences in chronic intragraft inflammation between positive crossmatch and ABO-incompatible kidney transplantation. | 24911035 |
| Inflammation, Renal glomerular disease | Altered Intercellular Communication | At 5 years, renal function was similar in ABOiKTx and conventional KTx, and both were higher than that of +XMKTx, which had higher rates of inflammation and chronic glomerulopathy on both 1- and 5-year biopsies. | 24911035 |
| Inflammation, graft loss | Altered Intercellular Communication | These data suggest that +XMKTxs have high rates of chronic inflammation at 1 and 5 years after transplantation, which may explain the higher rates of graft loss and lower renal function compared with other factors such as anti-donor antibody or intragraft complement deposition. | 24911035 |
| Autoimmune Diseases, Orbital Pseudotumor | Altered Intercellular Communication | An orbital biopsy showed a fibrotic idiopathic orbital inflammation (IOI) with, on immunohistochemical staining, an increased number of IgG4-positive plasma cells scored as >200 per high-power field, with IgG4/IgG ratio >0.50, indicating orbital IgG4 related autoimmune disease. | 24911364 |
| Inflammation, Hyperplasia | Altered Intercellular Communication | Microscopic evaluation of the excised lesion disclosed a pseudoadenomatous (pseudoglandular) hyperplasia of the conjunctival epithelium with myriad goblet cells and accompanying chronic inflammation. | 24911539 |
| Cessation of life, Inflammation, Blood Clot | Altered Intercellular Communication | The TIDE (Thrombus and Inflammation in sudden DEath) study. | 24912925 |
| Inflammation, Obesity | Altered Intercellular Communication | Telomere shortening is physiologically associated with ageing but it may be influenced by oxidative stress and chronic inflammation, linked to obesity. | 24913239 |
| Rheumatoid Arthritis, Pneumonitis | Altered Intercellular Communication | Rheumatoid arthritis-associated interstitial lung disease: lung inflammation evaluated with high resolution computed tomography scan is correlated to rheumatoid arthritis disease activity. | 24913966 |
| Inflammation, Refractory anemias, Fibrosis Assessment, Rheumatoid Factor, Rheumatoid Arthritis, Lung Diseases, Interstitial | Altered Intercellular Communication | To describe the association between rheumatoid arthritis disease activity (RA) and interstitial lung damage (inflammation and fibrosis), in a group of patients with rheumatoid arthritis-associated interstitial lung disease (RA-ILD). | 24913966 |
| Fibrosis Assessment, Pneumonitis | Altered Intercellular Communication | Interstitial lung inflammation and fibrosis were determined by Kazerooni scale. | 24913966 |
| Pneumonitis, Disease | Altered Intercellular Communication | These results suggest a positive association between RA disease activity and lung inflammation in RA-ILD. | 24913966 |
| Communicable Diseases, Inflammation | Altered Intercellular Communication | Gut colonization, inflammation and pro-carcinogenic potential were assessed in a chronic infection model using CEABAC10 transgenic mice. | 24914378 |
| Malignant tumor of colon, Communicable Diseases, Epithelial Damage, Colitis | Altered Intercellular Communication | In addition, in vivo experiments using a chronic infection model of CEACAM6 expressing mice showed that B2 E. coli strain 11G5 isolated from colon cancer is able to highly persist in the gut, and to induce colon inflammation, epithelial damages and cell proliferation. | 24914378 |
| Malignant tumor of colon, Inflammation, Carcinogenesis | Altered Intercellular Communication | In conclusion, these data bring new insights into the ability of E. coli isolated from patients with colon cancer to establish persistent colonization, exacerbate inflammation and trigger carcinogenesis. | 24914378 |
| Inflammation, Fibrosis Assessment | Altered Intercellular Communication | Histologic findings were consistent with a chronic inflammation with fibrosis. | 24914690 |
| ARCN1 gene, Inflammation, Chronic Obstructive Airway Disease, Endocrine System Diseases, Generalized amyotrophy | Altered Intercellular Communication | Skeletal muscle wasting commonly occurs in patients with chronic obstructive pulmonary disease (COPD) and has been associated with the presence of systemic inflammation and endocrinological disturbance. | 24915195 |
| Inflammation, Sleep Apnea, Obstructive, Osage language | Altered Intercellular Communication | Studies on inflammation biomarkers in serum and in exhaled breath condensate (EBC) in obstructive sleep apnea (OSA) have shown conflicting results. | 24915890 |
| Inflammation, Osage language | Altered Intercellular Communication | In mildly obese OSA patients, EBC biomarkers of inflammation or oxidative stress were normal at baseline and remained unchanged 3 months after UAS or CPAP. | 24915890 |
| Inflammatory abnormality of the eye | Altered Intercellular Communication | CD44 and RHAMM hyaluronan receptors in human ocular surface inflammation. | 24916930 |
| Inflammatory abnormality of the eye | Altered Intercellular Communication | The purpose of this research was to determine if CD44 and RHAMM are implicated in human ocular surface inflammation. | 24916930 |
| Inflammatory abnormality of the eye | Altered Intercellular Communication | Upper tarsal conjunctival epithelial samples from patients with active ocular surface inflammation (n = 17) and healthy controls (n = 14) were recovered by brush cytology. | 24916930 |
| Inflammation, Disease | Altered Intercellular Communication | Patients were evaluated by an ophthalmologist and classified in different groups according to the etiology (immune atopic diseases or immune non-atopic diseases) and inflammation intensity (mild/moderate or severe). | 24916930 |
| Inflammation, Disease | Altered Intercellular Communication | In immune atopic diseases, higher levels of CD44 and RHAMM mRNAs were present, reaching a 300 % increase for RHAMM in severe inflammation (p < 0.001). | 24916930 |
| Inflammatory abnormality of the eye | Altered Intercellular Communication | RHAMM may be implicated in severe ocular surface inflammation affecting the upper tarsal conjunctiva. | 24916930 |
| Inflammation | Altered Intercellular Communication | Histology showed mild chronic inflammation of the mucosa, but no ulceration. | 24916983 |
| Pleural Effusion, CTCAE, Inflammation, Hypertrophy | Altered Intercellular Communication | In February 2011, however, enlargement of the tumor with inflammation and right pleural effusion was found. | 24917412 |
| Inflammation, Hemorrhage, Neoplasms, Necrosis | Altered Intercellular Communication | Granulation due to old inflammation, precipitation of cholesterin crystals, hemorrhages, and necrosis were noted in the tumor. | 24917412 |
| Inflammation, Undifferentiated Connective Tissue Diseases | Altered Intercellular Communication | Our data suggest that the presence of inflammation and autoantibodies provoke endothelial cell activation and/or injury in UCTD patients. | 24917564 |
| Interstitial inflammation, Pneumonia | Altered Intercellular Communication | Radiological changes associated with both acute pneumonia and acute interstitial inflammation were observed in early H7N9 avian influenza cases. | 24917607 |
| Inflammation, Sleep Apnea, Obstructive, Dyslipidemias, Obesity | Altered Intercellular Communication | Obesity and obstructive sleep apnea tend to coexist and are associated with inflammation, insulin resistance, dyslipidemia, and high blood pressure, but their causal relation to these abnormalities is unclear. | 24918371 |
| Inflammation, Sleep Apnea, Obstructive, Hypertension, CTCAE | Altered Intercellular Communication | Obstructive sleep apnea is associated with hypertension, inflammation, and increased cardiovascular risk. | 24918372 |
| Inflammation, Pruritus | Altered Intercellular Communication | Instead, anti-inflammatory agents are used to reduce inflammation and therefore improve associated itch. | 24918564 |
| Inflammation | Altered Intercellular Communication | This supports the hypothesis that differences in growth rates and expression levels of complement, inflammation and apoptosis genes may result from population-specific, hereditary SNP variations in mtDNA. | 24919117 |
| Inflammation | Altered Intercellular Communication | The basic mechanism in obesity-related complications is chronic inflammation and increased oxidative stress. | 24920129 |
| Inflammation, Collagen Diseases, diabetic, Neuralgia, Eczema | Altered Intercellular Communication | Cocculus hirsutus (L.) Diels (Menispermaceae) is used in Indian folk system of alternative medicine for rheumatism, eczema, diabetics, inflammation, and neuralgia. | 24920232 |
| Inflammation, Endophthalmitis, CTCAE | Altered Intercellular Communication | Both patients had received other vascular endothelial growth factor inhibitors prior to aflibercept administration without signs of inflammation and both cases had sterile endophthalmitis. | 24920511 |
| ARCN1 gene, Chronic Obstructive Airway Disease, Airway structure | Altered Intercellular Communication | Despite a number of studies on biomarkers in chronic obstructive pulmonary disease (COPD), only a few disease-related markers have been identified, yet we still have no satisfactory markers specific to innate immune system and neutrophil activation, which is essential in airway inflammation in COPD. | 24920892 |
| Airway structure, ARCN1 gene | Altered Intercellular Communication | Recent biological studies indicated that lipocalins (LCNs) might be involved in airway inflammation and innate immunity; however, results from available studies on the association of LCNs with COPD are not consistent. | 24920892 |
| Asthma, Overweight, Obesity | Altered Intercellular Communication | Whether allergic airway inflammation mediates the association between overweight or obesity and childhood asthma is unknown. | 24922361 |
| Intraocular inflammation | Altered Intercellular Communication | Combined albendazole and corticosteroid therapy may reduce intraocular inflammation and recurrence. | 24922534 |
| Inflammation, Hemorrhage, Fibrosis Assessment, Congestion | Altered Intercellular Communication | Evaluation of each specimen was based on the presence of congestion, inflammation, hemorrhage and fibrosis. | 24922681 |
| Inflammation, Cardiovascular Diseases | Altered Intercellular Communication | Several studies have shown that serum bilirubin has a protective effect against cardiovascular disease and that inflammation plays an important role in its pathogenesis. | 24923275 |
| Gastric Adenocarcinoma, Primary malignant neoplasm, Inappropriate ADH Syndrome | Altered Intercellular Communication | To our knowledge, this is the first report of an antidiuretic hormone-secreting advanced gastric adenocarcinoma associated with the syndrome of inappropriate antidiuretic hormone, showing cancer cells immunostained for the antidiuretic hormone. | 24923603 |
| Primary malignant neoplasm, Stomach Carcinoma | Altered Intercellular Communication | Although a strong relationship between gastric cancer and the syndrome of inappropriate antidiuretic hormone remains to be established, we suggest that gastric cancer could be included as a differential diagnosis of cancer that is associated with the syndrome of antidiuretic hormone. | 24923603 |
| Inflammation, Hypertension, CTCAE, GDC Comorbidity Terminology, Diabetes Mellitus | Altered Intercellular Communication | Inflammation in response to comorbid conditions, such as hypertension and diabetes, may play a proportionally larger role in HFPEF as compared to HF with reduced ejection fraction (HFREF). | 24923671 |
| Inflammation | Altered Intercellular Communication | Inflammation mediated through TNFa and its receptors, TNFR1 and TNFR2, may represent an important component of a comorbidity-induced inflammatory response that partially drives the pathophysiology of HFPEF. | 24923671 |
| Communicable Diseases, Vertical Talus, Inflammation | Altered Intercellular Communication | The causes of CVT may be categorized into three main groups: hypercoagulable states, conditions causing blood flow disturbances, and all causes of inflammation or infection. | 24923843 |
| Inflammation, Malnutrition, Atherosclerosis | Altered Intercellular Communication | Malnutrition, inflammation, and atherosclerosis syndrome could be partially responsible for the observed association. | 24923997 |
| Chronic infectious disease, Allergic | Altered Intercellular Communication | Histopathology revealed abnormal lymphoplasmacytic inflammation of the mucosa in 4 of 5 biopsies of DS patients, consistent with chronic infection, allergic disease, or immune dysregulation. | 24924273 |
| Inflammation, Diabetes Mellitus, Non-Insulin-Dependent | Altered Intercellular Communication | Sedentary time and markers of inflammation in people with newly diagnosed type 2 diabetes. | 24925122 |
| Inflammation, Diabetes Mellitus, Non-Insulin-Dependent | Altered Intercellular Communication | We investigated whether objectively measured sedentary time was associated with markers of inflammation in adults with newly diagnosed type 2 diabetes. | 24925122 |
| Inflammation, Diabetes Mellitus, Non-Insulin-Dependent | Altered Intercellular Communication | Interventions to reduce sedentary time may help to reduce inflammation in women with type 2 diabetes. | 24925122 |
| Vasculitis, Dental Plaque, Cardiovascular Diseases | Altered Intercellular Communication | The effects of the mediterranean diet on biomarkers of vascular wall inflammation and plaque vulnerability in subjects with high risk for cardiovascular disease. | 24925270 |
| Inflammation, Lupus Nephritis, Lupus Erythematosus, Systemic | Altered Intercellular Communication | Lupus nephritis is a manifestation of SLE resulting from glomerular immune complex deposition and inflammation. | 24925725 |
| Intraocular inflammation, Ocular syphilis | Altered Intercellular Communication | British Ocular Syphilis Study (BOSS): 2-year national surveillance study of intraocular inflammation secondary to ocular syphilis. | 24925878 |
| Intraocular inflammation | Altered Intercellular Communication | Case definition was any adult presenting with intraocular inflammation in ES. | 24925878 |
| Communicable Diseases, Inflammation, Obesity | Altered Intercellular Communication | Although animal studies suggest that adenovirus 36 (Ad36) infection is linked to obesity and systemic inflammation, human data are scant and equivocal. | 24926952 |
| Inflammation | Altered Intercellular Communication | In children, our data suggest that Ad36(+) may be associated with biomarkers implicated in inflammation but not with greater levels of fat mass. | 24926952 |
| Gingivitis | Altered Intercellular Communication | Time course analysis of brachial artery flow mediated dilatation in subjects with gingival inflammation. | 24927022 |
| Inflammation, Endothelial dysfunction | Altered Intercellular Communication | Nevertheless, possible relationship between gingival inflammation and endothelial dysfunction observed over this temporal threshold remains still unexplored. | 24927022 |
| Ultraviolet B radiation, Malignant neoplasm of skin | Altered Intercellular Communication | Ultraviolet B (UVB) irradiation may cause oxidative stress- and inflammation-dependent skin cancer and premature aging. | 24927233 |
| Hepatitis | Altered Intercellular Communication | These findings suggest that IGT and DM may be causally implicated with liver inflammation process. | 24927611 |
| Inflammation, Edema | Altered Intercellular Communication | Antisecretory factor (AF) and derivates thereof counteract brain edema and inflammation, and normalize ICP dynamics. | 24928077 |
| Refractory anemias, Rheumatoid Arthritis, Inflammation, Cardiovascular morbidity | Altered Intercellular Communication | Rheumatoid arthritis (RA) is associated with increased cardiovascular morbidity and mortality attributed to traditional cardiovascular risk factors and/or the chronic systemic inflammation. | 24928345 |
| Inflammation, Metabolic Diseases | Altered Intercellular Communication | In recent years links among vitamin D deficiency, inflammation and cardio-metabolic disease were proposed. | 24928661 |
| Degenerative polyarthritis, Inflammation | Altered Intercellular Communication | Synovial fluid levels of adipokines in osteoarthritis: Association with local factors of inflammation and cartilage maintenance. | 24928914 |
| Degenerative polyarthritis, Inflammation | Altered Intercellular Communication | For this purpose, we investigated in patients with OA the relationships between the joint levels of leptin, adiponectin and resistin and those of factors involved in inflammation and cartilage maintenance. | 24928914 |
| Autoimmune Diseases, Inflammation, Primary malignant neoplasm, Bacterial Infections | Altered Intercellular Communication | They were identified originally in cancer patients and have since been reported to occur also in chronic inflammation, autoimmunity, and even bacterial infections. | 24929004 |
| Stomach Carcinoma | Altered Intercellular Communication | Gastric cancer (GC) is a progressive process initiated by Helicobacter pylori-induced inflammation. | 24929142 |
| HIV, Chronic inflammation, Depression, CTCAE | Altered Intercellular Communication | Human Immunodeficiency Virus (HIV) infection has been frequently associated with chronic inflammation as well as depression. | 24929193 |
| Inflammation, Depression, CTCAE | Altered Intercellular Communication | Further prospective study to confirm the role of inflammation in depression among HIV-positive people is warranted. | 24929193 |
| Inflammation, Atherosclerosis | Altered Intercellular Communication | Fractalkine (CX3CL1) is a chemokine associated with atherosclerosis and inflammation. | 24930044 |
| Fibrosis, Liver, Inflammation | Altered Intercellular Communication | All keratins were overexpressed in subjects with moderate vs. minimal inflammation, while K7, K8 and K18 were upregulated in patients with advanced liver fibrosis. | 24930437 |
| Parkinson Disease, Inflammation | Altered Intercellular Communication | Moderate-intensity interval training increases serum brain-derived neurotrophic factor level and decreases inflammation in Parkinson's disease patients. | 24930517 |
| Parkinson Disease, Inflammation | Altered Intercellular Communication | We have concluded that the improvement of health status of the Parkinson's disease patients after training could be related to the increase of serum BDNF level caused by the attenuated inflammation in those patients. | 24930517 |
| Renal Insufficiency, Inflammation, Fever, CTCAE, Polycystic Kidney, Autosomal Dominant, Pleural Effusion, CTCAE | Altered Intercellular Communication | A 64-year-old Japanese man with renal dysfunction caused by autosomal dominant polycystic kidney disease (ADPKD) was admitted to our hospital for evaluation of right back pain, fever, inflammation, and pleural effusion. | 24930657 |
| Pleural Effusion, CTCAE, Inflammation, Pain Distress Question | Altered Intercellular Communication | After drainage, the symptoms of inflammation, right back pain and right pleural effusion subsided. | 24930657 |
| Pleural Effusion, CTCAE, Inflammation, Communicable Diseases | Altered Intercellular Communication | The pleural effusion was due to the propagation of inflammation from the cyst infection. | 24930657 |
| Inflammation, Nasal Polyps, Chronic sinusitis | Altered Intercellular Communication | Chronic rhinosinusitis with nasal polyps is generally characterized by local Th2 inflammation and is categorized into two subtypes in Japan: eosinophilic chronic rhinosinusitis (similar to chronic rhinosinusitis with nasal polyps in western countries) and non-eosinophilic chronic rhinosinusitis (characterized by Th1-dominant inflammation). | 24931597 |
| Inflammation, Basal-Like Breast Carcinoma | Altered Intercellular Communication | Immunoglobulin free light chains are biomarkers of poor prognosis in basal-like breast cancer and are potential targets in tumor-associated inflammation. | 24931643 |
| Inflammation, Malignant Neoplasms | Altered Intercellular Communication | Inflammation is an important component of various cancers and its inflammatory cells and mediators have been shown to have prognostic potential. | 24931643 |
| Inflammation, Atherosclerosis | Altered Intercellular Communication | An abnormal profile in serum adipokines observed in AMI is related to systemic inflammation and the degree of atherosclerosis independently of glucose metabolism disturbances and heralds major adverse cardiovascular event occurrence in long-term observation. | 24933198 |
| Inflammation, Electrocardiogram: myocardial infarction (finding), Cardiovascular Diseases | Altered Intercellular Communication | Chemokines, including RANTES, play a crucial role in the processes of inflammation during cardiovascular disorders, including myocardial infarction, disease progression and complications. | 24934326 |
| Inflammation, "Alzheimers Disease", Data types - Address | Altered Intercellular Communication | Oxidative stress and inflammation are two key mechanisms suggested to be involved in the pathogenesis of Alzheimer's disease (AD). | 24934544 |
| Inflammation, Prostate, Benign prostatic hypertrophy | Altered Intercellular Communication | Benign prostatic hyperplasia (both with and without inflammation) was the commonest prostatic lesion and accounted for 80.3% of all cases and 97.6% of all benign cases. | 24935366 |
| Osteomyelitis, Inflammation | Altered Intercellular Communication | Although the affected patients showed all clinical signs of acute inflammation, expression levels in acute and secondary chronic osteomyelitis in the jaws did not reveal statistically significant differences compared with healthy bone samples. | 24935813 |
| Pain Distress Question, Primary malignant neoplasm, Phlebitis | Altered Intercellular Communication | During chemotherapy of cancer patients, vein inflammation may develop which may lead to pain and difficulty in blood sampling. | 24936574 |
| Cancer-related fatigue, Inflammation, Low muscle mass, Obesity, Visceral | Altered Intercellular Communication | Previous studies have shown that low cardiorespiratory fitness (CRF), visceral obesity and low muscle mass may share pathophysiological mechanisms, such as insulin resistance and chronic inflammation. | 24937121 |
| Inflammation, Injury of liver | Altered Intercellular Communication | IL-1alpha may have important role as marker of both inflammation and hepatic injury, particularly in the course of hepatitis B. | 24937930 |
| Hepatitis | Altered Intercellular Communication | IL-1alpha was significantly elevated in inflammatory conditions of pronounced activity (PCR positive hepatitis). | 24937930 |
| Ulcerative Colitis, Colitis | Altered Intercellular Communication | The association between pulmonary function impairment and colon inflammation in ulcerative colitis patients: A scientific basis for exterior-interior correlation between lung and large intestine. | 24938448 |
| Inflammation, Rupture | Altered Intercellular Communication | The results suggest that macrophage-mediated inflammation is a key biological pathway for IA rupture. | 24938844 |
| Inflammation, Necrosis | Altered Intercellular Communication | As expected, the presence of valve necrosis and acute inflammation decreased with an increase in time with respect to symptomatic onset. | 24939149 |
| Streptococcal Infections, Have Autoimmune or Inflammatory Condition, Bacterial Endocarditis | Altered Intercellular Communication | Histologic findings that mimic autoimmune inflammation are frequent in infective endocarditis and associated with streptococcal infection. | 24939149 |
| Inflammation, Small vessel vasculitis, Structure of vasa vasorum | Altered Intercellular Communication | There were no significant differences in the frequencies of positive TAB for classic transmural inflammation (28% vs 18.2%) or for periadventitial small vessel vasculitis and/or vasa vasorum vasculitis (6% vs 14.5%) between the two groups. | 24939678 |
| Necrotizing granulomatous inflammation, Giant Cell Arteritis, GCA gene | Altered Intercellular Communication | This was confirmed by targeted temporal artery biopsy, which showed chronic granulomatous inflammation typical of giant cell arteritis (GCA). | 24940569 |
| Tracheobronchitis, Ulceration, CTCAE | Altered Intercellular Communication | Simple tracheobronchitis was considered when the bronchoscopy report described mucosal inflammation and mucus secretions and invasive tracheobronchitis when ulceration and pseudomembrane formation was reported. | 24940892 |
| Refractory anemias, Rheumatoid Arthritis, Inflammation, Coronary Arteriosclerosis | Altered Intercellular Communication | The elevated risk of ischaemic heart disease in patients with rheumatoid arthritis (RA) has been linked to inflammation and disease severity. | 24941916 |
| Communicable Diseases, Inflammation, Biliary Dyskinesia | Altered Intercellular Communication | Biliary dyskinesia, inflammation or infection of the gallbladder was reported for 20 women (5%) and of those 13 had undergone gallbladder surgery. | 24942262 |
| Vasculitis, Atherosclerosis | Altered Intercellular Communication | Atherosclerosis is often associated with chronic vascular inflammation. | 24942794 |
| Malignant neoplasm of urinary bladder, Inflammation, Hyperplasia | Altered Intercellular Communication | Immunohistochemical staining for periplakin was shown to be significantly lower in bladder cancer tissues compared to non-cancerous tissues including inflammation,hyperplasia and normal urothelium. | 24942859 |
| Inflammation | Altered Intercellular Communication | The most common BAL cellular pattern was mixed inflammation with moderate lymphocytic and mild neutrophilic alveolitis. | 24942974 |
| Inflammation | Altered Intercellular Communication | Mixed inflammation with moderate lymphocytic and mild neutrophilic alveolitis is the most common BAL cellular pattern in patients with mAB-ILD. | 24942974 |
| Inflammation, Inflammatory Myofibroblastic Tumor | Altered Intercellular Communication | An inflammatory pseudotumor is a rare benign disease presenting with non-specific chronic inflammation, and reported occurrences involving the skull base are relatively rare. | 24943507 |
| Granuloma, Inflammation | Altered Intercellular Communication | Histologically, the oral pulse granuloma consists of multinucleated foreign body type giant cells, hyaline rings and chronic inflammation tissue. | 24943674 |
| Tolosa-Hunt Syndrome, Inflammation, Methylated spirit | Altered Intercellular Communication | Tolosa-Hunt syndrome (THS) is described as painful ophtalmoplegia caused by nonspesific inflammation of cavernous sinus or superior orbital fissure, which is response to steroid theraphy. | 24943858 |
| Vascular Diseases | Altered Intercellular Communication | This study aimed to observe the expression of inflammation-related factors in elderly T2DM patients with or without macrovascular disease (MVD). | 24943964 |
| Inflammation, Damage, Weight decreased | Altered Intercellular Communication | Magnesium deficiency significantly increased cisplatin-associated weight loss and markers of renal damage (plasma blood urea nitrogen and creatinine), histological changes, inflammation, and renal cell apoptosis and modulated signaling pathways (e.g., ERK1/2, p53, and STAT3). | 24944268 |
| Inflammation, Pancreatitis, Biliary calculi, Biliary Tract Neoplasm, Pancreatic Neoplasm | Altered Intercellular Communication | By analyzing the incidence of biliary stone and inflammation, pancreatitis, biliary duct tumors and pancreatic tumors between normal and abnormal types, significant differences existed. | 24944495 |
| Chronic folliculitis, Perifolliculitis | Altered Intercellular Communication | Histopathologic examination revealed perifollicular chronic and granulomatous inflammation, consistent with chronic folliculitis. | 24945647 |
| Inflammation, Pain, Postoperative | Altered Intercellular Communication | Antibiotics remove the local flora and reduce inflammation and thus may reduce postoperative pain after tonsillectomy. | 24946226 |
| Inflammation, Periodontitis, SMYD1 gene, Coronary heart disease | Altered Intercellular Communication | In coronary heart disease patients with periodontitis, BOP is strongly associated with systemic CRP levels; this association possibly reflects the potential significance of the local periodontal inflammatory burden for systemic inflammation. | 24946826 |
| Rupture, Hemorrhage, Inflammation, Blood Clot, Fibrous | Altered Intercellular Communication | Based on the presence and extent of histological features including haemorrhage, thrombus, fibrous tissue, lipid core, inflammation, neovascularity, foam cells, and cap rupture, 39 plaques were graded as predominantly stable, while 87 were predominantly unstable. | 24947079 |
| Communicable Diseases, Inflammation | Altered Intercellular Communication | Loss of cartilage will increase endplate permeability, facilitating endplate inflammation and disc infection. | 24947181 |
| Inflammation, Ovarian Cysts, Transcription Initiation | Altered Intercellular Communication | Given that chronic inflammation plays a central role in cancer initiation and progression, we selected and tested 15 cancer-related cytokines and growth factors in 38 ovarian cyst fluid samples. | 24947406 |
| Inflammation, Neoplasms, Ulcerative Colitis | Altered Intercellular Communication | The lack of correlation between well-known IBD-associated SNPs and UC-neoplasia demonstrated in this study suggests that the development of neoplasia in patients with UC is associated with genetic determinants other than those that predispose to inflammation or results from posttranslational modifications or epigenetic factors rather than germline polymorphisms. | 24947639 |
| Inflammation, Stomatitis, Denture | Altered Intercellular Communication | Denture stomatitis, inflammation and redness beneath a denture, affects nearly half of all denture wearers. | 24947908 |
| Inflammation, Hemorrhagic, Pain Distress Question | Altered Intercellular Communication | Main outcome measures were the incision inflammation rate, skin preparation time, presence of shaving-induced macroscopic haemorrhagic spots, verbal rating scale (VRS) pain score and satisfaction. | 24948414 |
| Inflammation, Dyslipidemias, Osteoporosis, Cardiovascular Diseases | Altered Intercellular Communication | The presence of common risk factors suggests that there is a relationship between osteoporosis and cardiovascular disease, possibly via dyslipidemia and inflammation. | 24949440 |
| Inflammation | Altered Intercellular Communication | A biopsy was taken and on histology, transmural granulomatous inflammation of numerous eosinophils, lymphocytes, plasmocytes and giant cells was seen. | 24950873 |
| Prostate carcinoma, prostatitis | Altered Intercellular Communication | Pentraxin 3: a novel biomarker for predicting progression from prostatic inflammation to prostate cancer. | 24950910 |
| Prostate carcinoma | Altered Intercellular Communication | Furthermore, we evaluated PTX3 serum concentrations in an independent set of patients with biopsy-proven inflammation/BPH (n = 61) and prostate cancer (n = 56). | 24950910 |
| Prostate, Prostate carcinoma | Altered Intercellular Communication | We found reduced PTX3 tissue expression in patients with prostatic inflammation/BPH compared with patients who developed prostate cancer. | 24950910 |
| Prostate carcinoma | Altered Intercellular Communication | PTX3 serum levels were also higher in patients with prostate cancer than in patients with inflammation/BPH. | 24950910 |
| Liver carcinoma | Altered Intercellular Communication | Usefulness of a new inflammation-based scoring system for prognostication of patients with hepatocellular carcinoma after hepatectomy. | 24950991 |
| Inflammation, Malnutrition, Communicable Diseases, malignant disease, Liver damage, Traumatic injury | Altered Intercellular Communication | Its serum level is reduced in many clinical conditions, such as liver damage, inflammation, injury, infection, malnutrition, and malignant disease. | 24951323 |
| Inflammation, Hemorrhage, Pain Distress Question | Altered Intercellular Communication | In addition to rapid bleeding control, the dressing causes minimal inflammation and pain and allows patients to quickly return to normal activities. | 24952410 |
| Cancer of Nasopharynx | Altered Intercellular Communication | Relationships between genetic polymorphisms in inflammation-related factor gene and the pathogenesis of nasopharyngeal cancer. | 24952889 |
| Inflammation, Hyperplasia, Chronic infectious disease | Altered Intercellular Communication | Pseudoepitheliomatous hyperplasia is a benign condition that may be caused by prolonged inflammation, chronic infection, and/or neoplastic conditions of the mucous membranes or skin. | 24953614 |
| Inflammation, Collagen Diseases | Altered Intercellular Communication | To determine the markers of systemic inflammation in soft tissue rheumatic disorders (STRDs). | 24953920 |
| Inflammation, Adiposis Dolorosa | Altered Intercellular Communication | Features of subtle systemic inflammation are positive in some cases of soft tissue rheumatism. | 24953920 |
| Inflammation, Arthritis, Psoriatic | Altered Intercellular Communication | S-calprotectin (S100A8/S100A9): a potential marker of inflammation in patients with psoriatic arthritis. | 24955375 |
| Inflammation, Obesity | Altered Intercellular Communication | Visceral adipose tissue (VAT) is a key contributor to chronic inflammation in obesity. | 24955608 |
| Inflammation, Diabetes Mellitus, Non-Insulin-Dependent, Obesity | Altered Intercellular Communication | ALOX 12 may have a critical role in regulation of inflammation in VAT in obesity and T2D. | 24955608 |
| Inflammation, Obesity | Altered Intercellular Communication | Selective ALOX 12 inhibitors may constitute a new approach to limit AT inflammation in human obesity. | 24955608 |
| Meningism, Inflammation, Edema | Altered Intercellular Communication | During hospitalization the patient's neurological status deteriorated, presenting signs of meningeal irritation along with signs of inflammation and oedema of the right knee. | 24955800 |
| Necrotizing granulomatous inflammation, Tuberculosis | Altered Intercellular Communication | Histopathological assessment unexpectedly revealed a chronic granulomatous inflammation compatible with tuberculosis. | 24955803 |
| Inflammation, Asthma | Altered Intercellular Communication | Potentially pathogenic airway bacteria and neutrophilic inflammation in treatment resistant severe asthma. | 24955983 |
| Asthma | Altered Intercellular Communication | Such changes may have relevance to treatment-resistant severe asthma, particularly those with neutrophilic airway inflammation, as bacteria might be anticipated to activate the innate immune response, a process that is poorly steroid responsive. | 24955983 |
| Airway structure, Asthma, Airway Obstruction | Altered Intercellular Communication | Airway colonisation with potentially pathogenic micro-organisms in asthma is associated with more severe airways obstruction and neutrophilic airway inflammation. | 24955983 |
| Inflammation, Whole-Body Irradiation, Traumatic, Blood Coagulation Disorders | Altered Intercellular Communication | Traumatic brain injury (TBI) has a complex pathophysiology that involves coagulopathy and inflammation. | 24956150 |
| Inflammation | Altered Intercellular Communication | Life-course-persistent asthma is related to a proposed biomarker of accelerated aging, possibly via systemic eosinophilic inflammation. | 24956257 |
| Granulomatous inflammation | Altered Intercellular Communication | Histopathological results confirmed granulomatous inflammation in 38 patients (93%). | 24956337 |
| Inflammation, Metabolic Syndrome X | Altered Intercellular Communication | Insulin resistance and systemic inflammation, but not metabolic syndrome phenotype, predict 9 years mortality in older adults. | 24956526 |
| Increased insulin level, Aggressive behavior, Inflammation | Altered Intercellular Communication | Adipokine secretion and AKT/mTOR activation play important roles in obesity-accelerated breast cancer aggressiveness in addition to hyperinsulinemia, estrogen signaling, and inflammation. | 24957076 |
| Communicable Diseases, Inflammation | Altered Intercellular Communication | Decreased CFTR expression and/or function lead to impaired airway surface liquid (ASL) volume homeostasis, resulting in accumulation of mucus, reduced clearance of bacteria, and chronic infection and inflammation. | 24957904 |
| Sepsis, Inflammation | Altered Intercellular Communication | Redox state of pentraxin 3 as a novel biomarker for resolution of inflammation and survival in sepsis. | 24958171 |
| Inflammation, Malignancy-associated membranous nephropathy, Edema | Altered Intercellular Communication | Solid-organ malignancy-associated CSVV was less likely to demonstrate papillary dermal oedema (P = 0*04), papillary dermal inflammation (P < 0*001) and lymphocytes (P < 0*001), and more likely to have plasma cells (P = 0*02). | 24958433 |
| Inflammation, Fibrosis Assessment | Altered Intercellular Communication | Single blinded pathologist interpretation was performed, with inflammation, fibrosis, neovascularization, foreign body (FB) reaction, and wall thickness assessed semi-quantitatively and scored from 0-3. | 24958647 |
| Inflammation, Fibrosis Assessment | Altered Intercellular Communication | Varying degrees of inflammation and fibrosis were common features at all times. | 24958647 |
| Amyloidosis, Nephrosis, Fibrinoid necrotizing inflammation | Altered Intercellular Communication | ABT improved rheumatoid inflammation and AA amyloidosis, one case showing clinical remission and the other demonstrating incomplete recovery of nephrosis but stable kidney function. | 24959698 |
| Fibrinoid necrotizing inflammation | Altered Intercellular Communication | One case showed complete regression of AA amyloid fibrils in serial upper gastrointestinal biopsies, but the other case still had AA amyloid deposits despite ABT-induced normalised rheumatoid inflammation, with polymorphonuclear leukocytes and macrophages infiltrating tissues containing AA amyloid. | 24959698 |
| Inflammation | Altered Intercellular Communication | The results do not necessarily reflect Doppler evaluation as being ineffective, but may be caused by DAS28 not being a perfect marker of inflammation. | 24960526 |
| Inflammation, Data types - Address | Altered Intercellular Communication | Aggregated amyloid-b (Ab), oxidative stress, and inflammation have pivotal roles in the pathogenesis of AD. | 24960578 |
| Periapical bone loss, Inflammation | Altered Intercellular Communication | In patients with periapical lesions and patients after root canal therapy, the concentrations of cytokines did not indicate for the systemic inflammation. | 24960621 |
| Chronic Kidney Diseases | Altered Intercellular Communication | Plasma concentrations of IL-6 and TNF-a appear to be more sensitive markers of odontogenic inflammation in CKD patients than CRP. | 24960621 |
| Low Back Pain, Inflammation | Altered Intercellular Communication | This produces common low back pain by causing inflammation and sensitization of the peridural membrane and periosteum that forms the boundaries of this compartment. | 24961282 |
| Inflammation, Liver Dysfunction | Altered Intercellular Communication | There was an even greater improvement when olive and fish oils were also added with higher incidence of resolution of abnormal liver function tests and reduced inflammation. | 24961544 |
| Inflammation | Altered Intercellular Communication | However, MRI may be helpful in showing typical findings including perivascular space inflammation and enhancement. | 24962051 |
| Sepsis, Inflammation | Altered Intercellular Communication | Persistent inflammation and T cell exhaustion in severe sepsis in the elderly. | 24962182 |
| Sepsis, Inflammation | Altered Intercellular Communication | Although aging is crucial in sepsis, the impact of aging on inflammation and immunosuppression is still unclear. | 24962182 |
| Sepsis, Inflammation | Altered Intercellular Communication | Persistent inflammation and T cell exhaustion may be associated with decreased survival in elderly patients and mice after sepsis. | 24962182 |
| palladium, Dysautonomia | Altered Intercellular Communication | Our goal is to report the cardiac sympathetic neurotransmission in de novo Brazilian patients with sporadic PD, without clinically defined dysautonomia. | 24964109 |
| palladium, Dysautonomia | Altered Intercellular Communication | We concluded that 123I cMIBG has been able to identify cardiac sympathetic neurotransmission disorder in Brazilian de novo PD patients without clinically defined dysautonomia. | 24964109 |
| Inflammation, Communicable Diseases, Thoracic Injuries, Pseudoaneurysm, Acute myocardial infarction, Myocardial rupture | Altered Intercellular Communication | Pseudoaneurysm is a very rare and unusual form of myocardial rupture, with complications such as chest trauma, inflammation, acute myocardial infarction, and infection. | 24964750 |
| Gingivitis, Periodontitis, Tooth Loss | Altered Intercellular Communication | Salivary cortisol levels in the patients with periodontitis were correlated with worse PI, higher gingival inflammation, and greater tooth loss. | 24965061 |
| Inflammation, Hematoma, Sinusitis | Altered Intercellular Communication | Orbital inflammation secondary to sinusitis is common in children, whereas orbital subperiosteal hematoma secondary to sinusitis is extremely rare, with only 11 reported cases, including one case in children. | 24965687 |
| Inflammation, Hematoma | Altered Intercellular Communication | Our review of literature shows that sudden onset, afebrile, and few signs of inflammation on blood test in patients with subperiosteal lesion may indicate subperiosteal hematoma. | 24965687 |
| Inflammation, Atrophic | Altered Intercellular Communication | Patients with cagA-positive H. pylori could be at higher risk for severe inflammation and atrophy. | 24965801 |
| Inflammation, Intracranial Aneurysm | Altered Intercellular Communication | As there is increasing evidence that inflammation is contributing significantly to the pathogenesis of intracranial aneurysms, melanocyte-like cells may be relevant in preventing age-related impairment of vessels. | 24967348 |
| Inflammation, No metabolic abnormalities, Hepatocarcinogenesis | Altered Intercellular Communication | Obesity-related metabolic abnormalities, including adipokine imbalance and chronic inflammation, are involved in liver carcinogenesis. | 24968270 |
| Inflammation | Altered Intercellular Communication | Chemerin, a novel adipokine, plays a critical role in adipogenesis, energy metabolism, and inflammation. | 24968270 |
| Inflammation, Atherosclerosis | Altered Intercellular Communication | DPP4 activity is an important predictor of the onset of inflammation and atherosclerosis in apparently healthy Chinese. | 24968315 |
| Inflammation, B-Cell Lymphomas | Altered Intercellular Communication | Serum lactate dehydrogenase with a systemic inflammation score is useful for predicting response and survival in patients with newly diagnosed diffuse large B-cell lymphoma. | 24969101 |
| HD Term Type, Inflammation | Altered Intercellular Communication | Also, inflammation is a common feature in HD patients. | 24969183 |
| Inflammation, Malnutrition, Atherosclerosis | Altered Intercellular Communication | Therefore, a low level of fetuin-A seems to be associated with atherosclerosis, inflammation and malnutrition. | 24969186 |
| Crohn Disease, Intestinal Microbiome, Gastrointestinal inflammation | Altered Intercellular Communication | Recent studies indicate that persistent intestinal inflammation in patients with Crohn's disease (CD) might be caused by abnormal intestinal microbiota. | 24969283 |
| Inflammation, Perforation (observation) | Altered Intercellular Communication | The question of feasibility also arises in cases of advanced inflammation with perforation. | 24969344 |
| Inflammation, Neuroendocrine Tumors | Altered Intercellular Communication | Furthermore, there were two findings without inflammation, namely one neurogenic appendicopathy and one neuroendocrine tumor. | 24969344 |
| Narcolepsy, Sleep Disorders | Altered Intercellular Communication | These sleep problems partly resemble the core symptoms of narcolepsy, a sleep disorder caused by a general loss of the neurotransmitter hypocretin. | 24969517 |
| Inflammation, Depression, CTCAE, Diabetes Mellitus, Non-Insulin-Dependent, Diabetes Mellitus | Altered Intercellular Communication | Because of the absence of data on the direct association between inflammation and depression in patients with diabetes, we examined the association between hs-CRP levels and the high prevalence of depression in adult patients with type 2 diabetes. | 24969579 |
| Inflammation | Altered Intercellular Communication | Plasma neutrophil gelatinase-associated lipocalinin in the general population: association with inflammation and prognosis. | 24969771 |
| Data types - Address | Altered Intercellular Communication | The results suggest an early functional impairment of cholinergic neurotransmission in AD, which is associated to early changes in the excitability of the motor system. | 24969819 |
| Inflammation | Altered Intercellular Communication | IRIS consists in a sudden change in the dominant T-helper responses to inflammation, which is not balanced by anti-inflammatory response, playing a critical role in microbial pathogenesis. | 24970001 |
| Inflammation, Diabetes Mellitus, Non-Insulin-Dependent, Inflammatory disorder, Cardiovascular Diseases | Altered Intercellular Communication | The risk of cardiovascular diseases and type 2 diabetes mellitus is increased across a range of organ-specific and multisystem chronic inflammatory disorders with evidence that risk is associated with severity of inflammation. | 24970784 |
| Refractory anemias | Altered Intercellular Communication | Recently, A20 was identified as a key negative regulator for T cell activation and inflammatory signaling and may be involved in RA pathogenesis. | 24971370 |
| Inflammation, Ulcerative Colitis | Altered Intercellular Communication | Sixteen polymorphisms in 13 genes involved in regulation of inflammation were associated with risk of CD and/or UC (p <= 0.05). | 24971461 |
| Inflammation, GRN wt Allele | Altered Intercellular Communication | Collectively, our findings suggest that circulating PGRN is significantly associated with systemic insulin sensitivity and autophagic activity in adipose tissue and support the notion that PGRN functions as a potential link between chronic inflammation and insulin resistance. | 24971611 |
| Ischemia, Inflammation, Neurotoxicity Syndromes | Altered Intercellular Communication | Plant hydroethanolic extracts were prepared and tested in a panel of phenotypic screening assays that reflect multiple neurotoxicity pathways relevant to AD-oxytosis in hippocampal nerve cells, in vitro ischemia, intracellular amyloid toxicity, inhibition of microglial inflammation and nerve cell differentiation. | 24971794 |
| Inflammation, Visceral Pain | Altered Intercellular Communication | Visceral pain is strongly associated with inflammation and distension of the gut. | 24972070 |
| Inflammation, Aortic Aneurysm, Abdominal, atherosclerotic | Altered Intercellular Communication | Atherosclerotic risk factors and atherosclerotic postoperative events are associated with low inflammation in abdominal aortic aneurysms. | 24972144 |
| Inflammation, Glucocorticoid deficiency with achalasia, atherosclerotic, Atherosclerotic lesion | Altered Intercellular Communication | Low amount of inflammation in AAAs is associated with more atherosclerotic risk factors, more advanced local atherosclerotic lesions and more postoperative atherosclerotic adverse events. | 24972144 |
| Peripheral Vascular Diseases | Altered Intercellular Communication | Autologous bone marrow mononuclear cell therapy improves symptoms in patients with end-stage peripheral arterial disease and reduces inflammation-associated parameters. | 24972744 |
| Inflammation | Altered Intercellular Communication | Autologous BM-MNC therapy in patients with end-stage PAD improves tissue perfusion indices and decreases markers of inflammation. | 24972744 |
| Inflammation, Observation Method - Coagulation | Altered Intercellular Communication | Proteinase-activated receptor-1 (PAR-1) plays a key role in mediating the interplay between coagulation and inflammation in response to injury. | 24973402 |
| Inflammation | Altered Intercellular Communication | Laboratory data: elevated transaminases, markers of inflammation negative, all bacterial cultures negative. | 24974673 |
| Inflammation, Respiratory Failure, Thrombocytopenia | Altered Intercellular Communication | Subsequently, the inflammation, respiratory failure, and thrombopenia rapidly improved, and the patient was extubated on day 12. | 24974932 |
| Inflammation, Primary malignant neoplasm, Neoplasms, Muscle (organ) | Altered Intercellular Communication | There is limited information on the impact of age, sex, tumor type, and inflammation on muscle loss in the end of life of cancer patients. | 24975045 |
| Inflammation, Primary malignant neoplasm, Neoplasms, Muscle (organ) | Altered Intercellular Communication | Muscle loss in advanced cancer is related to age, sex, tumor type, and inflammation. | 24975045 |
| Inflammation, Fatigue | Altered Intercellular Communication | Among various psychological stress response variables, general fatigue may be a key determinant of low-grade inflammation as represented by increases of WBC and neutrophil counts. | 24975105 |
| Granulomatous inflammation | Altered Intercellular Communication | Granulomatous inflammation was the most frequent histological finding (56%). | 24975504 |
| Inflammation, Obesity | Altered Intercellular Communication | High-oleic peanuts: new perspective to attenuate glucose homeostasis disruption and inflammation related obesity. | 24975522 |
| Inflammation, Deep thrombophlebitis | Altered Intercellular Communication | We found no evidence of systemic inflammation in patients with PTS at 63months since the last DVT. | 24975586 |
| Inflammation, Primary malignant neoplasm, Neoplasms | Altered Intercellular Communication | Inflammation perpetuates individual tumor progression resulting in decreased survival in cancer patients. | 24975677 |
| Inflammation, Inflammatory disorder, Pyeloureteritis cystica | Altered Intercellular Communication | Pyeloureteritis cystica is described as a benign inflammatory disease of the urinary tract, resulting from chronic inflammation of the urothelium. | 24975787 |
| ARCN1 gene, Inflammation, alpha 1-Antitrypsin Deficiency | Altered Intercellular Communication | These data show that AATD COPD patients do not experience the same chronic systemic inflammation and exhibit reduced inflammation compared to non-AATD COPD patients. | 24975928 |
| Inflammation, Disease | Altered Intercellular Communication | Therefore, alterations in innate immunity could explain the inflammation and T-cell autoreactivity leading to the development of LP disease. | 24976336 |
| ARCN1 gene, Inflammation | Altered Intercellular Communication | Long-term home noninvasive mechanical ventilation (NIV) is beneficial in COPD but its impact on inflammation is unknown. | 24976687 |
| Pneumonitis | Altered Intercellular Communication | These findings challenge prior paradigms based on the assumption that pulmonary inflammation is per se detrimental. | 24976687 |
| Autoimmune Diseases, Arthralgia, Chemosis of conjunctiva, Xerostomia, Orbital Pseudotumor, Inflammatory disorder | Altered Intercellular Communication | Female gender, family history of autoimmune disease, self-reported joint pain or dry mouth, external signs of orbital inflammation, and conjunctival chemosis were more common in patients with inflammatory systemic disease as compared with that in patients with no identifiable condition (P < 0.05 for all). | 24977987 |
| Scleritis, Secondary glaucoma | Altered Intercellular Communication | Scleritis with secondary glaucoma, although usually associated with inflammatory conditions, can rarely be a manifestation of adult T-PLL. | 24977988 |
| Sialadenitis, Inflammation, Fibrosis Assessment, Atrophic | Altered Intercellular Communication | Subsequent biopsy of the left lacrimal gland revealed chronic inflammation with lymphoid aggregate formation, atrophy, and fibrosis consistent with chronic sialadenitis, and an incisional biopsy of the cervical lymph node showed salivary gland tissue with inflammation as well. | 24978334 |
| Cherubism, Inflammation, Osteopenia | Altered Intercellular Communication | Etanercept administration to neonatal SH3BP2 knock-in cherubism mice prevents TNF-a-induced inflammation and bone loss. | 24978678 |
| Cherubism, Inflammation, destruction joint, Erosion of bone | Altered Intercellular Communication | In a knock-in mouse model for cherubism, we previously demonstrated that homozygous mutant mice develop T/B cell-independent systemic macrophage inflammation leading to bone erosion and joint destruction. | 24978678 |
| Cherubism, Tumor necrosis, bone destruction, Inflammation | Altered Intercellular Communication | We identified a critical role of tumor necrosis factor a (TNF-a) in the development of autoinflammation by creating homozygous TNF-a-deficient cherubism mutants, in which systemic inflammation and bone destruction were rescued. | 24978678 |
| Inflammation, Osteopenia | Altered Intercellular Communication | However, inflammation and bone loss, which were successfully treated by etanercept administration, recurred after etanercept discontinuation. | 24978678 |
| Cherubism, Inflammation, Pneumonitis, Osteopenia | Altered Intercellular Communication | In contrast, when 10-week-old cherubism mice with fully active inflammation were treated with etanercept for 7 weeks, even the high-dose administration did not decrease bone loss or lung or liver inflammation. | 24978678 |
| Inflammation, Chronic Kidney Diseases | Altered Intercellular Communication | The relation of hepcidin to iron disorders, inflammation and hemoglobin in chronic kidney disease. | 24978810 |
| Inflammation, Chronic Kidney Diseases | Altered Intercellular Communication | We investigated its relation to iron disorders, inflammation and hemoglobin (Hb) level in 199 non-dialyzed, non-transplanted patients with CKD stages 1-5. | 24978810 |
| Sepsis, Inflammation | Altered Intercellular Communication | Age-related differences in biomarkers of acute inflammation during hospitalization for sepsis. | 24978893 |
| Sepsis | Altered Intercellular Communication | Adjustment or stratification by sepsis severity did not change the age-inflammation associations. | 24978893 |
| Sepsis, Inflammation, Septic Shock | Altered Intercellular Communication | Although older adults had higher levels of inflammation at presentation and an increased incidence of severe sepsis and septic shock, these age-related differences in inflammation largely resolved during the first 72 h of hospitalization. | 24978893 |
| Inflammation, selenium, Chaos | Altered Intercellular Communication | Our results suggest that SES moderates the detrimental effect of family chaos on systemic inflammation and interleukin-6 (B = -0.010, standard error [SE] = 0.004, p = .026), but not C-reactive protein (B = 0.009, SE = 0.006, p = .11), and on stimulated proinflammatory cytokine production (B = -0.098, SE = 0.044, p = .026) in adolescents, such that a chaotic family environment is positively associated with greater systemic inflammation and greater stimulated proinflammatory cytokine production in adolescents as family SES declines. | 24979577 |
| Inflammatory disorder | Altered Intercellular Communication | These findings indicate that living in chaotic family environments places youth who may be vulnerable based on socioeconomic factors at a potentially higher risk for inflammation-related diseases. | 24979577 |
| Inflammatory abnormality of the eye, Sensorineural Hearing Loss (disorder), Autoimmune vasculitis, Oculovestibuloauditory syndrome | Altered Intercellular Communication | Cogan's syndrome (CS) is a rare autoimmune vasculitis characterized by ocular inflammation and sensorineural hearing loss. | 24979832 |
| Autoimmune Diseases, Sensorineural Hearing Loss (disorder), Inflammatory abnormality of the eye | Altered Intercellular Communication | "Atypical" CS is conceivably a sort of "melting pot" of different forms of autoimmune diseases still characterized by ocular inflammation and sensorineural hearing loss but whose antigenic characteristics need to be further defined. | 24979832 |
| Inflammation | Altered Intercellular Communication | Dynamics of inflammation resolution and symptom recovery during AECOPD treatment. | 24980048 |
| Airway structure, ARCN1 gene | Altered Intercellular Communication | The association between increases in both systemic and airway inflammation and acute exacerbation of COPD (AECOPD) has been reported by many studies. | 24980048 |
| Dyspnea, Upper Respiratory Infections | Altered Intercellular Communication | Notably, lung function and dyspnea improved to the baseline level by day 4 as well, consistent with the resolution of respiratory inflammation. | 24980048 |
| Airway structure | Altered Intercellular Communication | In summary, we observed a time lag between the resolution of systemic and airway inflammation, which were correlated with the improvements of different clinical indices. | 24980048 |
| Inflammation, Impaired cognition | Altered Intercellular Communication | Disability was associated with the DC (crude odds ratio, OR: 2.1; 95% confidence interval, CI: 1.4-3.4), CCI (crude OR: 1.8; 95% CI: 1.2-2.7) and CIRS (crude OR: 4.0; 95% CI: 2.5-6.5); only the association with CIRS was independent of age, sex, chronic inflammation, impaired cognition and frailty (adjusted OR: 3.2; 95% CI: 1.7-5.8). | 24980394 |
| Inflammation, Impaired cognition, Frailty | Altered Intercellular Communication | Frailty was associated with CCI (crude OR: 2.4; 95% CI: 1.2-4.6) and CIRS (crude OR: 2.6; 95% CI: 1.3-5.3); adjusted for age, sex, chronic inflammation, impaired cognition and disability. | 24980394 |
| Migraine Disorders, Inflammation | Altered Intercellular Communication | We propose that in our patient the occipital neurocysticercosis lesions cause migraine without aura-like attacks via inflammation in the surrounding brain parenchyma leading to sensitization of the trigemino-vascular system. | 24980846 |
| Diverticulitis, Inflammatory disease of mucous membrane, Diverticular Diseases | Altered Intercellular Communication | Diverticular colitis is a newly established disorder of chronic segmental mucosal inflammation affected by diverticular disease. | 24980998 |
| Inflammation, Coronary Artery Disease, Diabetes Mellitus | Altered Intercellular Communication | Insights from a thermography-based method suggesting higher carotid inflammation in patients with diabetes mellitus and coronary artery disease. | 24981292 |
| Inflammation | Altered Intercellular Communication | Alterations in the pouch and the proximal SB were comparable, suggesting that inflammation may not be limited to the pouch, but that it extends to the proximal SB. | 24982202 |
| Inflammation, Rheumatoid Factor | Altered Intercellular Communication | Endogenous MMP-9 and not MMP-2 promotes rheumatoid synovial fibroblast survival, inflammation and cartilage degradation. | 24982240 |
| Refractory anemias, Inflammation | Altered Intercellular Communication | Additionally, MMP-9 stimulates RA synovial fibroblast-mediated inflammation and degradation of cartilage, whereas MMP-2 inhibits these parameters. | 24982240 |
| Malignant Biliary Obstruction | Altered Intercellular Communication | Inflammation-based prognostic score predicts biliary stent patency in patients with unresectable malignant biliary obstruction. | 24982377 |
| Primary malignant neoplasm | Altered Intercellular Communication | An inflammation-based prognostic score, the modified Glasgow prognostic score (mGPS), has been reported to be useful for predicting postoperative survival in patients with various types of cancer. | 24982377 |
| Inflammation, Malnutrition | Altered Intercellular Communication | Prealbumin and albumin may be sensitive indicators of disturbances in protein metabolism, and reflect inflammation activity and malnutrition. | 24982401 |
| Inflammation, Malignant Neoplasms | Altered Intercellular Communication | The neutrophil:lymphocyte ratio (NLR) has been reported to reflect systemic inflammation and to have independent prognostic value for patients with various cancers. | 24982408 |
| Inflammation | Altered Intercellular Communication | Noninfectious inflammation after intravitreal injection of aflibercept: clinical characteristics and visual outcomes. | 24983791 |
| Inflammation | Altered Intercellular Communication | To report the presenting features and clinical outcomes of a series of patients with noninfectious inflammation after intravitreal aflibercept injection. | 24983791 |
| Inflammation | Altered Intercellular Communication | Medical records of patients who presented with noninfectious inflammation after intravitreal aflibercept injection between November 18, 2011 and June 30, 2013 were retrospectively reviewed. | 24983791 |
| Inflammatory Bowel Diseases, Gastrointestinal inflammation | Altered Intercellular Communication | Role of HMGB1 as a suitable biomarker of subclinical intestinal inflammation and mucosal healing in patients with inflammatory bowel disease. | 24983978 |
| Inflammatory Bowel Diseases, Gastrointestinal inflammation | Altered Intercellular Communication | Noninvasive biomarkers of high- and low-grade intestinal inflammation and of mucosal healing (MH) in patients with inflammatory bowel disease are currently lacking. | 24983978 |
| Inflammation | Altered Intercellular Communication | We have recently shown that fecal high mobility group box 1 (HMGB1) protein is a novel biomarker of gut inflammation. | 24983978 |
| Inflammation | Altered Intercellular Communication | We aimed at investigating in a mouse model if HMGB1 was able to foresee both a clinically evident and a subclinical gut inflammation and if its normalization indicated MH. | 24983978 |
| Inflammation | Altered Intercellular Communication | Fecal HMGB1 increased by 5-, 11-, 18-, and 24-folds with dextran sodium sulphate doses of 0.25%, 0.50%, 1%, and 4%, respectively, showing that the protein detected a high-grade and a subclinical inflammation. | 24983978 |
| Inflammation | Altered Intercellular Communication | Fecal HMGB1 is a robust noninvasive biomarker of clinically overt and subclinical gut inflammation; it can also be a surrogate marker of MH. | 24983978 |
| Arterial Stiffness, Inflammation, ETV3 wt Allele | Altered Intercellular Communication | Secondary endpoints included characteristics of the MetS, namely endothelial function, arterial stiffness and inflammation. | 24984823 |
| Inflammation, Obstructive sialadenitis, Rectal Obstruction, CTCAE | Altered Intercellular Communication | Obstructive sialadenitis of a transplanted submandibular gland: chronic inflammation secondary to ductal obstruction. | 24985728 |
| Inflammation, Obstructive sialadenitis, Rectal Obstruction, CTCAE | Altered Intercellular Communication | Obstructive sialadenitis of transplanted SMGs is a chronic inflammation secondary to ductal obstruction, which leads to insufficient ocular lubrication and potential treatment failure. | 24985728 |
| Communicable Diseases, Idiopathic bronchiectasis, Inflammation, Damage | Altered Intercellular Communication | Idiopathic bronchiectasis is a poorly defined disease characterised by persistent inflammation, infection and progressive lung damage. | 24986480 |
| Inflammation, Breast Carcinoma, Malignant Neoplasms | Altered Intercellular Communication | Chronic inflammation is associated with increased risk of multiple cancers, including breast cancer. | 24986698 |
| Airway structure, Asthma, Respiratory Tract Infections | Altered Intercellular Communication | Vitamin D modifies airway inflammation and appears to be important in building immunity against respiratory infections, and so is potentially beneficial in asthma. | 24986817 |
| Refractory anemias, Inflammation, Tumor necrosis | Altered Intercellular Communication | Despite elevated systemic inflammation [interleukin (IL)-6, IL-18, tumor necrosis factor-a; p < 0.05 for all], persons with RA were not less insulin sensitive [SI geometric mean (SD): RA 4.0 (2.4) vs control 4.9 (2.1)*10(-5) min(-1)/(pmol/l); p = 0.39]. | 24986846 |
| Refractory anemias, Inflammation | Altered Intercellular Communication | In established and treated RA, traditional risk factors, specifically excess adiposity, play more of a role in predicting skeletal muscle insulin sensitivity than do systemic inflammation or other disease-related factors. | 24986846 |
| Inflammation | Altered Intercellular Communication | There was a good correlation between CCE and colonoscopy in disease severity (k=0.79; 95% confidence interval: 0.62-0.96) and extent of inflammation (k=0.71; 95% confidence interval: 0.52-0.90) observed. | 24987825 |
| Inflammation, Refractory anemias, Rheumatoid Arthritis, Inflammatory disorder, Diabetes Mellitus, Non-Insulin-Dependent | Altered Intercellular Communication | Type 2 diabetes is associated with chronic, low-grade inflammation and could potentially trigger the progression of other, more prominent inflammatory diseases such as rheumatoid arthritis (RA). | 24988532 |
| Refractory anemias, Inflammation, Diabetes Mellitus, Non-Insulin-Dependent | Altered Intercellular Communication | Our findings were consistent with the hypothesis that chronic low-grade inflammation in type 2 diabetes may elicit the development of RA in genetically susceptible individuals. | 24988532 |
| Inflammation, Cachexia, Malignant Head and Neck Neoplasm | Altered Intercellular Communication | The purpose of this study was to evaluate the prognostic potential of the modified Glasgow prognostic score (mGPS), known to reflect the degree of tumor-associated inflammation and cancer cachexia, in patients with advanced head and neck cancer. | 24989115 |
| Inflammation, Chronic granulomatous disease | Altered Intercellular Communication | Clinically, dysregulated inflammation by excessive cytokine production due to loss of reactive oxygen species production is suggested as a cause of noninfectious inflammatory problems such as chronic granulomatous disease colitis. | 24989247 |
| Inflammation, Fibrosis Assessment, Insemination, Artificial, Homologous | Altered Intercellular Communication | Five remarkable points should be emphasized: (i) a long latency interval, despite the acute presentation; (ii) exacerbation of liver biochemical parameters, even after drug cessation; (iii) the paired liver biopsies indicating continuing inflammation and disappearance of toxic features; (iv) a positive DLST and the absence of fibrosis consistent with DIAIH and not AIH; and (v) a rare histological feature of MS. Intense immunoallergic reactions were likely triggers of MS in the current case. | 24989642 |
| Icterus, Inflammation | Altered Intercellular Communication | A possibility of DIAIH should be considered in cases of DILI which exhibit overt jaundice, autoantibodies, intense histological inflammation and a long latency period. | 24989642 |
| Eosinophilic inflammation | Altered Intercellular Communication | Nasal fluid release of eotaxin-3 and eotaxin-2 in persistent sinonasal eosinophilic inflammation. | 24989688 |
| Refractory anemias, Rheumatoid Arthritis, Inflammation | Altered Intercellular Communication | Despite enrichment of Treg cells in joints of rheumatoid arthritis (RA) patients, local inflammation persists. | 24990235 |
| Inflammation, Liver Cirrhosis, FAM126A gene | Altered Intercellular Communication | HCC predominantly develops in the condition of chronic inflammation that has led to liver cirrhosis. | 24990270 |
| Inflammation, Ischemic stroke | Altered Intercellular Communication | Immune responses and inflammation are key elements in the pathogenesis of ischemic stroke (IS). | 24991091 |
| Inflammation, HIV Infections | Altered Intercellular Communication | Chronic inflammation is a hallmark of HIV infection. | 24991090 |
| Pancreatitis | Altered Intercellular Communication | Our study demonstrated that cryptogenic pancreatic inflammation with fatty changes represents an important predisposing factor for PDAC. | 24991971 |
| Waldenstrom Macroglobulinemia, Fibrosis Assessment | Altered Intercellular Communication | Biopsy specimens taken from the parietal pleura revealed lymphoplasmacytic inflammation with fibrosis. | 24992134 |
| Inflammation, Chronic Obstructive Airway Disease | Altered Intercellular Communication | Critical role of RIG-I-like receptors in inflammation in chronic obstructive pulmonary disease. | 24992168 |
| Airway structure, ARCN1 gene | Altered Intercellular Communication | Our results suggested that MDA-5, but not RIG-I, may play a critical role in airway inflammation in COPD. | 24992168 |
| Communicable Diseases, Postoperative Complications, Inflammation | Altered Intercellular Communication | A high preoperative CRP level predicts an increased rate of postoperative complication due to established inflammation and/or infection. | 24992421 |
| Histiocytosis, Langerhans-Cell, Inflammation | Altered Intercellular Communication | Oral manifestion of Langerhans cell histiocytosis mimicking inflammation. | 24992857 |
| Histiocytosis, Langerhans-Cell, Inflammation | Altered Intercellular Communication | A case of LCH in a 6-year-old girl involving the mid root level of developing first permanent molar with a floating developing tooth bud of permanent second molar mimicking an inflammation is reported. | 24992857 |
| Inflammation, Ulcerative Colitis | Altered Intercellular Communication | Fecal level of calprotectin identifies histologic inflammation in patients with ulcerative colitis in clinical and endoscopic remission. | 24993368 |
| Inflammation, Colorectal Neoplasms | Altered Intercellular Communication | Persistent active microscopic inflammation is associated with an increased risk of relapse and colorectal neoplasia. | 24993368 |
| Inflammation, Ulcerative Colitis | Altered Intercellular Communication | Histologic inflammation is common among patients with UC in clinical and endoscopic remission. | 24993368 |
| Inflammation, Eosinophilic esophagitis, Esophagitis | Altered Intercellular Communication | Markers of eosinophilic inflammation for diagnosis of eosinophilic esophagitis and proton pump inhibitor-responsive esophageal eosinophilia: a prospective study. | 24993367 |
| Inflammation, Diabetes Mellitus, Non-Insulin-Dependent, Chronic Kidney Diseases | Altered Intercellular Communication | Long-term effects of moderate protein diet on renal function and low-grade inflammation in older adults with type 2 diabetes and chronic kidney disease. | 24993749 |
| Communicable Diseases, Inflammation | Altered Intercellular Communication | Osteopontin (OPN) and soluble urokinase plasminogen activator receptor (suPAR) have been proposed as markers of disease severity and risk-stratification in infection and inflammation. | 24994498 |
| Inflammation | Altered Intercellular Communication | Because of the acute onset and signs of acute inflammation, an X-ray was arranged. | 24995443 |
| Inflammation, Cardiovascular Diseases, Cyclophosphamide/Vincristine/Dacarbazine Regimen, Diabetes Mellitus, Chronic Kidney Diseases | Altered Intercellular Communication | Inflammation, oxidative stress, and diabetes are common in patients with chronic kidney disease (CKD), particularly in those with cardiovascular disease (CVD). | 24995525 |
| Inflammation, Diabetes Mellitus | Altered Intercellular Communication | The coexistence of diabetes and oxidative stress independently affected CCL23 levels, while the presence of CVD and inflammation had no impact on its concentrations. | 24995525 |
| Inflammation, Prostate carcinoma | Altered Intercellular Communication | The neutrophil-to-lymphocyte ratio (NLR), a marker of inflammation, has been reported to be a poor prognostic indicator in prostate cancer. | 24995769 |
| Inflammation, Asteroids | Altered Intercellular Communication | A fine-needle cytology of the axillary lymph node showed extensive granulomatous inflammation, numerous histiocytes, and multinucleated giant cells containing star-shaped structures known as "asteroid bodies." | 24995825 |
| Carcinogenesis, Malignant Neoplasms, Pancreatitis | Altered Intercellular Communication | Regenerating islet-derived protein 3-alpha (Reg3A) has been reported overexpressed in pancreatic inflammation and associated with PaC malignancies, thus believed as a potential target in inflammation-linked pancreatic carcinogenesis. | 24996521 |
| Inflammation, Cyst | Altered Intercellular Communication | We drained the cyst using transesophageal endoscopic ultrasonography to control the inflammation and decrease the size of the cyst; we subsequently resected the cyst. | 24996718 |
| prostatitis, Erectile dysfunction | Altered Intercellular Communication | Asymptomatic prostatic inflammation in men with clinical BPH and erectile dysfunction affects the positive predictive value of prostate-specific antigen. | 24996777 |
| Sexual Dysfunction, Benign prostatic hypertrophy, prostatitis | Altered Intercellular Communication | To test the hypothesis that sexual dysfunction in elderly men with benign prostatic hyperplasia leads to prostatic inflammation, diagnosed by prostatic fluid interleukin-8 (IL-8), which lowers the positive predictive value of prostate-specific antigen (PSA). | 24996777 |
| Inflammation, Benign prostatic hypertrophy, Erectile dysfunction | Altered Intercellular Communication | Men with symptomatic benign prostatic hyperplasia and erectile dysfunction had significant inflammation of the prostate to cause spurious rise in PSA level resulting in an unnecessary biopsy. | 24996777 |
| Drug-induced, Psychogenic | Altered Intercellular Communication | The causes of ED was classified as psychogenic (59.2%), vasoculogenic (21.3%), neurogenic (4.1%), anatomical/structural (2.8%), hormonal (7.1%) or drug-induced (5.5%). | 24996819 |
| Inflammation | Altered Intercellular Communication | Aging is commonly accompanied by increased arterial and ventricular stiffness (determined by arterial elastance (Ea) and ventricular elastance (Elv)), augmented ventricular-vascular coupling ratios (Ea/Elv) and systemic inflammation. | 24996847 |
| Inflammation | Altered Intercellular Communication | Acute inflammation may impact ventricular-vascular coupling and predispose older adults to cardiovascular events. | 24996847 |
| Each (qualifier value) | Altered Intercellular Communication | Ea and Ea/Elv were maintained (p > 0.05), but Elv was reduced (p < 0.05) 24 h post-inflammation. | 24996847 |
| Inflammation | Altered Intercellular Communication | Older, but not younger, adults decreased central pressure during inflammation (p < 0.05). | 24996847 |
| Inflammation | Altered Intercellular Communication | Aging, not physical activity, appears to modulate cardiovascular responses to acute inflammation, except in the most active older adults. | 24996847 |
| Aggressive course, "Alzheimers Disease", Depressed mood | Altered Intercellular Communication | Monoaminergic neurotransmitter alterations in postmortem brain regions of depressed and aggressive patients with Alzheimer's disease. | 24997673 |
| APP gene, Inflammation, vascular associated smooth muscle cell apoptotic process, Aortic Aneurysm, Abdominal | Altered Intercellular Communication | The pathogenesis of abdominal aortic aneurysm (AAA) formation includes inflammation, vascular smooth muscle cell apoptosis, extracellular matrix degradation, and oxidative stress. | 24997808 |
| Inflammation, Metabolic Syndrome X, Cardiovascular Diseases | Altered Intercellular Communication | C-reactive protein (CRP) is a marker of inflammation which has been shown in multiple prospective epidemiological studies to predict the risk of cardiovascular disease and metabolic syndrome. | 24998076 |
| Inflammation, Disease, Obesity | Altered Intercellular Communication | Inflammation may accompany obesity and a variety of diseases, or result from excessive exercise. | 24998353 |
| Interstitial inflammation, Cyst, Pleurisy, Bronchiolitis, muscle hyperplasia, Infiltration | Altered Intercellular Communication | Pathologically, in the UIP/pSS group, interstitial inflammation, plasma cell infiltration, lymphoid follicles with germinal centers, cysts, bronchiolitis, and pleuritis were significantly more prominent, whereas smooth muscle hyperplasia and fibroblastic foci were milder (all P<0.05). | 24998369 |
| Airway structure, Residual volume | Altered Intercellular Communication | Formoterol and budesonide may inhibit RV infection by reducing the ICAM-1 levels and/or acidic endosomes and modulate airway inflammation associated with RV infections. | 24998372 |
| Inflammation | Altered Intercellular Communication | Elderly individuals usually present chronic low level inflammation, likely as the consequence of continued exposure to antigens combined with poor immune function, increases in production of pro-inflammatory cytokines by effector memory and senescent T cells and macrophages. | 24998470 |
| Inflammation | Altered Intercellular Communication | In this work we analyse NK cell subsets in the elderly in relation with markers of inflammation and health status. | 24998470 |
| Inflammation, Skin Basal Cell Carcinoma | Altered Intercellular Communication | We conclude that NLR, a basal cancer related inflammation marker, is associated with the resistance to bevacizumab- based treatments in mCRC patients. | 24998541 |
| Inflammation, Crohn Disease | Altered Intercellular Communication | To define the best independent predictors for active inflammation in patients with Crohn disease (CD) examined by contrast-enhanced magnetic resonance (MR) enterography. | 24998692 |
| Inflammation, With intensity | Altered Intercellular Communication | The bowel wall T2 hyperintensity and the length of the involved bowel tract were predictors of active inflammation in patients with CD examined by contrast-enhanced MR enterography. | 24998692 |
| Inflammation, Abnormal degeneration | Altered Intercellular Communication | Muscle biopsy typically reveals endomysial inflammation, invasion of mononuclear cells into non-necrotic fibers and rimmed vacuoles, suggesting inflammation and degeneration co-exist as part of the pathomechanism. | 24998819 |
| Inflammation, TP53 gene, Neoplasms | Altered Intercellular Communication | Loss of Cdh1 and Trp53 in the uterus induces chronic inflammation with modification of tumor microenvironment. | 24998851 |
| Inflammation, Neoplasms | Altered Intercellular Communication | These results indicate that absence of CDH1 and TP53 in endometrial cells initiates chronic inflammation, promotes tumor microenvironment development following the recruitment of macrophages and promotes aggressive ECs. | 24998851 |
| Inflammation, Hyperkeratosis, Koilocytotic atypia, Hypergranulosis, Acanthosis, Hyperplasia | Altered Intercellular Communication | Punch biopsy of the hallux nail bed revealed epidermal hyperplasia, acanthosis, hypergranulosis, hyperkeratosis, and regions of koilocytosis without significant inflammation. | 24999548 |
| Retinal Vasculitis, Inflammatory abnormality of the eye | Altered Intercellular Communication | Disease activity markers, including signs of ocular inflammation, evidence of retinal vasculitis, Swedish interactive threshold algorithm-short wavelength automated perimetry Humphrey visual field analysis, electroretinographic parameters, and optical coherence tomography were recorded. | 24999722 |
| Intraocular inflammation | Altered Intercellular Communication | Intraocular inflammation was present in 54.5, 9.9, 11.1, and 0% of patients at baseline, 6 months, 1 year, 2 years, 3 years, and beyond 3 years after receiving the implant, respectively. | 24999722 |
| Inflammation, Plaque, Atherosclerotic | Altered Intercellular Communication | The degree of inflammation within the atherosclerotic plaque can be detected non-invasively by positron emission tomography (PET) with 18F-fluorodeoxyglucose (18F-FDG). | 25000124 |
| Dermatitis, Eczema | Altered Intercellular Communication | Chronic hand eczema is defined as a persistent (>6 months' duration) noninfectious skin inflammation of the hands. | 25000239 |
| Inflammation | Altered Intercellular Communication | Russell body esophago-gastro-duodenitis is an unusual form of chronic inflammation, with only 22 cases being reported in PubMed. | 25001185 |
| Inflammation, Tooth structure, Tooth Loss, Osteopenia | Altered Intercellular Communication | Characteristics of AP are gingival inflammation, deep periodontal pockets, bone loss, tooth mobility and even tooth loss. | 25001360 |
| Gingivitis | Altered Intercellular Communication | A 4-year-old girl presented with signs of severe gingival inflammation. | 25001360 |
| Parotitis, Juvenile rheumatoid arthritis | Altered Intercellular Communication | Juvenile recurrent parotitis (JRP) is a nonobstructive, nonsuppurative parotid inflammation in young children. | 25001449 |
| Inflammation, Hemorrhage, Communicable Diseases, Cartilaginous exostosis, Irritation | Altered Intercellular Communication | It is well established that irregular bursae can form adjacent to an osteochondroma (bursa exostotica) as a result of mechanical irritation and that these bursae can be complicated by inflammation, hemorrhage, or infection. | 25001874 |
| Alzheimers Disease", Inflammation | Altered Intercellular Communication | Isolation of glia from Alzheimer's mice reveals inflammation and dysfunction. | 25002035 |
| Impaired cognition, Data types - Address, physiopathological | Altered Intercellular Communication | Based on these findings we argue that chronically proinflammatory astrocyte and microglia phenotypes, showing a reduction of genes involved in neuronal support and neuronal signaling, are likely to contribute to the neuronal dysfunction and cognitive decline in AD. | 25002035 |
| Inflammation, COL4A2 wt Allele, Edema | Altered Intercellular Communication | We hypothesized that modulation of brain inflammation reduces edema, thus improving clinical outcomes in patients with ICH. | 25003359 |
| Inflammation, Acanthosis, Fibrosis Assessment | Altered Intercellular Communication | Pathology specimens from skin flaps showed extensive acute and chronic inflammation, microabscesses, fibrosis, and acanthosis, with depletion and degeneration of the pilosebaceous units. | 25003411 |
| Inflammation, Tumor necrosis, Pain Distress Question, MMP8 wt Allele | Altered Intercellular Communication | While studies suggest an association between chronic inflammation and pain, levels of inflammatory cytokines, such as C-reactive protein (CRP) and tumor necrosis factor-alpha (TNF-a), have not been correlated with pain in HNC patients who are not currently undergoing anticancer treatment. | 25003634 |
| Inflammation, Anemia, HIV Infections | Altered Intercellular Communication | Markers of inflammation and activation of coagulation are associated with anaemia in antiretroviral-treated HIV disease. | 25003720 |
| Inflammation, Anemia, Thrombophilia | Altered Intercellular Communication | Persistent inflammation and hypercoagulation appear to be associated with anaemia. | 25003720 |
| Left Ventricular Hypertrophy, Inflammation, Cardiomyopathies, Myocardial dysfunction, Atherosclerosis | Altered Intercellular Communication | Epicardial adipose tissue is related to coronary atherosclerosis, left ventricle hypertrophy, myocardial dysfunction, cardiomyopathy, and inflammation, which produces a variety of cytokines that influence key pathogenic mechanisms of atherogenesis. | 25004239 |
| Carcinomatosis, Inflammation | Altered Intercellular Communication | Inflammation plays a central role in peritoneal carcinomatosis (PC) etiology and progression, and circulating levels of inflammatory biomarkers prior to surgery predict progression-free and overall survival in PC patients. | 25004281 |
| Pain Distress Question, Inflammation | Altered Intercellular Communication | Her shoulder pain worsened, and examination demonstrated inflammation over the sternoclavicular joint. | 25004310 |
| Arthritis | Altered Intercellular Communication | Thus, anti-CII antibodies may both contribute to, as well as be the consequence of, local joint inflammation. | 25005029 |
| Inflammation | Altered Intercellular Communication | The present case reinforces the notion that Modic type I change corresponds to reversible local inflammation. | 25005163 |
| Communicable Diseases, Uveitis | Altered Intercellular Communication | We describe a rare case of extraocular inflammation secondary to scleral buckle infection with Alcaligenes xylosoxidans. | 25005211 |
| Celiac Disease, Inflammation, Crypt hyperplasia, Villous atrophy | Altered Intercellular Communication | The small-bowel mucosal damage characteristic of celiac disease (CD) develops from normal villus morphology to inflammation and finally to villus atrophy with crypt hyperplasia. | 25005738 |
| Ulcer, Inflammation, Crohn Disease | Altered Intercellular Communication | The VCE in May 2007 found patchy inflammation and superficial ulcers in the terminal ileum consistent with Crohn's disease. | 25006053 |
| Inflammation, Intraepithelial Lymphocytosis, Colitis | Altered Intercellular Communication | Nine years later, a colectomy revealed a form of microscopic colitis in which significant intraepithelial lymphocytosis and collagen plate thickening have disappeared while GCs persisted with diffuse mononuclear cells inflammation of the lamina propria. | 25006169 |
| Inflammation | Altered Intercellular Communication | Esophagogastric fistula is a rare complication related to severe inflammation at the gastroesophageal junction. | 25007128 |
| Inflammation | Altered Intercellular Communication | Macrophages are important components of the tumor-associated infiltrate and are qualified as one of the major players of the cancer-related inflammation. | 25007179 |
| Airway structure, ARCN1 gene | Altered Intercellular Communication | Eosinophilic airway inflammation is observed in 10-30% of COPD subjects. | 25007795 |
| Acute Coronary Syndrome | Altered Intercellular Communication | They represent an important mode of intercellular communication, and their number is increased in patients with acute coronary syndromes. | 25007837 |
| Inflammatory abnormality of the eye | Altered Intercellular Communication | Control of ocular inflammation was achieved in 38 of 40 (95%). | 25007956 |
| Traumatic, Thyrotoxicosis, Thyroiditis | Altered Intercellular Communication | Thyroid function tests confirmed the clinical suspicion of progressive thyrotoxicosis, with associated imaging consistent with thyroid inflammation secondary to band-like traumatic pressure to the lower half of the thyroid gland. | 25008337 |
| Inflammation, Contrast - Induced Nephropathy | Altered Intercellular Communication | The role of inflammation in contrast-induced nephropathy. | 25009948 |
| Inflammation, Cervical Intraepithelial Neoplasia | Altered Intercellular Communication | Ongoing inflammation doubles the likelihood of development of CIN. | 25009948 |
| Inflammation, Cervical Intraepithelial Neoplasia | Altered Intercellular Communication | This study highlights the importance of inflammation as a risk factor in the development of CIN. | 25009948 |
| Lower Urinary Tract Symptoms, prostatitis | Altered Intercellular Communication | Effects of prostatic inflammation on LUTS and alpha blocker treatment outcomes. | 25010301 |
| prostatitis | Altered Intercellular Communication | Prostatic inflammation was scored as none (0), mild (I), moderate (II), or marked (III). | 25010301 |
| Inflammation | Altered Intercellular Communication | Lower grade inflammation was related to higher urine flow rate at baseline. | 25010301 |
| Inflammation | Altered Intercellular Communication | Patients with higher inflammation grades had larger prostate volumes, larger total and transitional zone volumes, and higher PSA levels. | 25010301 |
| Inflammation, Lower Urinary Tract Symptoms | Altered Intercellular Communication | Eighty percent of patients with grade 0 inflammation, 73% of patients with grade I inflammation, and 92.3% of patients with grade II inflammation showed improvement of LUTS after treatment. | 25010301 |
| Inflammation, Prostate | Altered Intercellular Communication | Patients with high grade inflammation had lower flow rates and higher prostatic volumes than patients with low grade inflammation. | 25010301 |
| Acute inflammation, cell wall thickening | Altered Intercellular Communication | Of these 65 patients, 61 underwent scrotoscopy and minimal hydrocelectomy, two patients underwent open hydrocelectomy because thickening of hydrocele wall was identified; two patients with acute inflammation only underwent scrotoscopy. | 25010305 |
| Inflammation | Altered Intercellular Communication | There was a significant reduction in the area and severity of the palatal inflammation (P < .0001). | 25010873 |
| Inflammation, Chronic disease | Altered Intercellular Communication | Many biodemographic studies use biomarkers of inflammation to understand or predict chronic disease and aging. | 25011077 |
| Inflammation | Altered Intercellular Communication | chronic low-grade inflammation during aging, is commonly characterized by pro-inflammatory biomarkers. | 25011077 |
| Inflammation, Diabetes Mellitus, Non-Insulin-Dependent | Altered Intercellular Communication | Simple therapeutic strategies targeted at attenuating the progression of chronic low-grade inflammation and insulin resistance are urgently required to prevent or slow the development of type 2 diabetes in susceptible individuals. | 25011647 |
| Weight Gain, Inflammation, Skeletal muscle structure | Altered Intercellular Communication | Despite similar weight gain, subjects with smaller fat cells at baseline had a greater decrease in insulin sensitivity, which was linked with upregulated skeletal muscle tissue inflammation. | 25011943 |
| Inflammation, Units Of Measure - Siemens | Altered Intercellular Communication | Expression of genes involved in inflammation and tissue remodeling in VAT and liver showed a similar alteration pattern in MHO and MAO individuals. | 25011950 |
| Inflammation, Fibrosis Assessment, Phlebitis | Altered Intercellular Communication | More than 80 % of the left thyroid lobe was effaced by fibrosis and inflammation (lymphocytes, 57 IgG4+ plasma cells per 1 high-power field, an IgG4/IgG ratio of 0.67, and eosinophils) with extension into the surrounding tissues and occlusive phlebitis. | 25011997 |
| Inflammation, Benign prostatic hypertrophy | Altered Intercellular Communication | Prevalence of inflammation and benign prostatic hyperplasia on autopsy in Asian and Caucasian men. | 25012523 |
| Inflammation, Benign prostatic hypertrophy | Altered Intercellular Communication | Inflammation has been suggested to be involved in the pathogenesis of benign prostatic hyperplasia (BPH). | 25012523 |
| Inflammation | Altered Intercellular Communication | We correlated the presence and grade of acute inflammation (AI) or chronic inflammation (CI) and BPH. | 25012523 |
| Inflammation, Benign prostatic hypertrophy | Altered Intercellular Communication | In this study, we looked at the prevalence of inflammation and benign prostatic hyperplasia (BPH) on autopsy in Asian and Caucasian men. | 25012523 |
| Inflammation | Altered Intercellular Communication | We found chronic inflammation in>70% of men on autopsy. | 25012523 |
| Inflammation | Altered Intercellular Communication | More chronic inflammation was associated with more BPH. | 25012523 |
| Psychotic Disorders | Altered Intercellular Communication | An overactive striatal dopaminergic neurotransmission is described in psychosis and may be associated with a state of aberrant salience attribution. | 25012755 |
| Inflammation | Altered Intercellular Communication | Chronic inflammation was thought to be more important than the other existing plausible hypotheses in the course of TO. | 25013916 |
| Traumatic, Pneumonitis, Pneumonia | Altered Intercellular Communication | In addition, survival and pulmonary inflammation were measured in mice undergoing traumatic brain injury with or without pneumonia. | 25014065 |
| Inflammation, Atherosclerosis | Altered Intercellular Communication | Soluble urokinase plasminogen activator receptor (suPAR), a marker of inflammation, has been associated with subclinical atherosclerosis. | 25014213 |
| Inflammation, Primary Biliary Cholangitis, Immune-mediated, Intrahepatic bile duct | Altered Intercellular Communication | PBC is characterized by portal inflammation and immune-mediated destruction of intrahepatic bile ducts in liver histology and the presence of antimitochondrial antibodies in the serum of nearly 95% of patients. | 25014239 |
| Inflammation | Altered Intercellular Communication | Angiotensin receptor 1 blockade reduces secretion of inflammation associated cytokines from cultured human carotid atheroma and vascular cells in association with reduced extracellular signal regulated kinase expression and activation. | 25016365 |
| Inflammation, Atheroma | Altered Intercellular Communication | Our findings suggest that ATR1 blockade downregulates atheroma tissue ERK1/2 expression leading to a reduction in cytokine production and that a non-AII agonist ATR1 signalling response may induce expression of these inflammation associated cytokines in the atheroma. | 25016365 |
| Inflammation, Thoracic Injuries | Altered Intercellular Communication | High-mobility group box 1 (HMGB1), a key late mediator of systemic inflammation, is a potentially useful biomarker for predicting outcome in patients with severe blunt chest trauma. | 25016440 |
| Inflammation, Carcinogenesis, Adenomatous Polyps | Altered Intercellular Communication | It has been shown that local chronic inflammation may lead to colorectal carcinogenesis via adenomatous polyps. | 25016780 |
| Inflammation, Neoplasms | Altered Intercellular Communication | Tumor necrosing factor-alpha (TNF-alpha), interleukin-6 (IL-6) and C-reactive protein (CRP) are biomarkers of inflammation and indicators of the immune response to tumors. | 25016780 |
| Inflammation, Fibrosis Assessment, Tissue injury, Bronchiectasis | Altered Intercellular Communication | Th17 cells play a crucial role in neutrophilic inflammation and tissue injury in non-cystic fibrosis (non-CF) bronchiectasis. | 25016929 |
| Inflammation | Altered Intercellular Communication | This grading system offers a means of assessing the degree of inflammation and facilitates speculation about the duration of VKH disease. | 25017008 |
| Carcinoma | Altered Intercellular Communication | The mean age of patients with severe dysplasia/carcinoma and invasive carcinoma was significantly older than that of inflammation/hyperplasia (F = 6.773, P < 0.05) . | 25017219 |
| Squamous Hyperplasia, Inflammation, Dysplasia, Carcinoma | Altered Intercellular Communication | In 138 patients, 85 patients (61.6%) were pathologically diagnosed as chronic inflammation or squamous epithelium hyperplasia, 18 patients (13.0%) as mild dysplasia, 10 patients (7.2%) as moderate dysplasia, 15 patients (10.9%) as severe dysplasia/carcinoma in situ and 10 patients (7.2%) as invasive carcinoma. | 25017219 |
| Dysplasia | Altered Intercellular Communication | 68.5% vocal folds with inflammation/hyperplasia showed nearly normal mucosal waves, and 72.7% to 80.0% vocal folds with moderate or more severe dysplasia showed severe reduced mucosal waves. | 25017219 |
| Inflammation, Ocular Hypertension, Edema, Cataract, Glaucoma, CTCAE | Altered Intercellular Communication | Control of inflammation, improvement of visual acuity (VA) to >= 20/40, improvement of VA loss attributed to macular edema (ME), incident cataract affecting VA, cataract surgery, ocular hypertension, and glaucoma surgery. | 25017415 |
| Delirium, Inflammation | Altered Intercellular Communication | A possible neuroinflammatory basis for delirium is likely and C-reactive protein (CRP) as a marker for inflammation can possibly play a predictive role. | 25017770 |
| Childhood Leiomyosarcoma, Arteritis | Altered Intercellular Communication | Histologic findings showed an arterial leiomyosarcoma combined with elements of arterial inflammation. | 25017783 |
| Airway structure, Wheezing, Nasal allergies, Rhinitis | Altered Intercellular Communication | We assessed whether airway inflammation markers were associated with nasal allergies and self-reported symptoms of wheeze and rhinitis in 130 children 6-12 year old in an epidemiological context. | 25019424 |
| allergic inflammation | Altered Intercellular Communication | In conclusion, FeNO and nasal tryptase reflect allergic inflammation in the respiratory system. | 25019424 |
| Inflammation, Hostility | Altered Intercellular Communication | Trait hostility is associated with systemic inflammation in married couples: an actor-partner analysis. | 25019591 |
| Inflammation, Hostility, Anger, Coronary heart disease | Altered Intercellular Communication | Trait anger and hostility predict the development of coronary heart disease, and systemic inflammation may partly mediate this association. | 25019591 |
| Inflammation, Impaired cognition, Depressed mood | Altered Intercellular Communication | Although it is well established that late-life depression is associated with both systemic low-graded inflammation and cognitive impairment, the relation between inflammation and cognition in depressed older persons is still equivocal. | 25019974 |
| Inflammation, Fibrosis Assessment, Granuloma | Altered Intercellular Communication | We sought to determine whether anti-TNF-a therapy affects histologic inflammation, fibrosis, and granuloma formation. | 25022570 |
| Inflammation, Granuloma | Altered Intercellular Communication | Compared with controls, the group treated with anti-TNF-a showed a reduction in mucosal and submucosal inflammation (P < .05), a decrease in granuloma formation (P < .05), and an increase in duplication of the muscularis mucosae (P < .05). | 25022570 |
| Inflammation, Fibrosis Assessment, Granuloma | Altered Intercellular Communication | Resection specimens from patients with CD treated with anti-TNF-a therapy showed (a) reduced mucosal and submucosal inflammation; (b) a decrease in granuloma formation; and (c) a distinct pattern of submucosal hyaline fibrosis, with increased fibrosis in the muscularis mucosae and muscularis propria. | 25022570 |
| Locally Advanced Unresectable Colorectal Adenocarcinoma | Altered Intercellular Communication | Inflammation-based prognostic scores and nutritional prognostic index in patients with locally-advanced unresectable colorectal cancer. | 25022764 |
| Inflammation, Periodontitis, Osteopenia | Altered Intercellular Communication | This leads to inflammation of the pulp (pulpitis), soft tissue breakdown, and finally to bone loss around the root apex (apical periodontitis). | 25022970 |
| Inflammation | Altered Intercellular Communication | Inflammation contributes to hemopoiesis by lowering responses to epoetin (EPO) and to an increase in the mortality of patients on hemodialysis. | 25023457 |
| Inflammation | Altered Intercellular Communication | However, nutritional status might alter associations among inflammation, EPO responsiveness, and the risk of mortality. | 25023457 |
| Stillbirth, Spontaneous abortion, Cardiovascular Diseases, Cyclophosphamide/Vincristine/Dacarbazine Regimen, Pregnancy loss | Altered Intercellular Communication | Metabolic, hormonal, and hemostatic changes associated with pregnancy loss (stillbirth and miscarriage) may contribute to the development of cardiovascular disease (CVD) in adulthood. | 25024237 |
| Alzheimers Disease", Data types - Address | Altered Intercellular Communication | Synaptosomal-associated protein of 25 kDa (SNAP-25) is an age-regulated vesicular SNARE protein involved in the exocytosis of neurotransmitters from synapses, a process that is altered in Alzheimer's disease (AD). | 25024311 |
| Inflammation, Endothelial dysfunction | Altered Intercellular Communication | To investigate pro-atherosclerotic markers (endothelial dysfunction and inflammation) in patients one year after liver transplantation. | 25024624 |
| Swelling, Telangiectasis | Altered Intercellular Communication | At each visit, patients were evaluated for redness, swelling, wound healing, scar formation, tissue inflammation/atrophy, telangiectasis, and pigmentary disturbances. | 25025385 |
| Granulomatous inflammation, Necrosis, Pauci-Immune Glomerulonephritis - Renal Limited | Altered Intercellular Communication | A nephrectomy was performed that demonstrated a discrete lesion with extensive necrosis, granulomatous inflammation, and crescentic pauci-immune glomerulonephritis, findings consistent with GPA. | 25025447 |
| Inflammation, cyclosporine, Endothelial dysfunction, Angina Pectoris, Variant | Altered Intercellular Communication | Patients with coronary spastic angina (CSA) also have endothelial dysfunction and inflammation. | 25025992 |
| Inflammation, Endothelial dysfunction | Altered Intercellular Communication | Activation of PPAR-g improves endothelial dysfunction and inflammation. | 25025992 |
| Inflammation, glycation | Altered Intercellular Communication | Advanced glycation end products (AGEs) may promote inflammation by interacting with the receptor for advanced glycation end products. | 25026914 |
| Inflammation, Periodontal Diseases, Diabetes Mellitus | Altered Intercellular Communication | Periodontal disease is related to aging, smoking habits, diabetes mellitus, and systemic inflammation. | 25026916 |
| Xanthogranulomatous inflammation, Granulomatous Endometritis, Xanthogranulomatous salpingitis, Endometritis | Altered Intercellular Communication | Although xanthogranulomatous endometritis and xanthogranulomatous salpingitis of the female genital tract has been described previously, to the best of our knowledge, this is the first report of xanthogranulomatous inflammation with infiltration into the uterine myometrium from the perimetrium without endometritis. | 25027857 |
| Xanthogranulomatous inflammation | Altered Intercellular Communication | Histopathological findings revealed that the abscess was caused by xanthogranulomatous inflammation with the granulation tissue and chronic inflammatory cells that consisted of focal and sheets of foam cells. | 25027857 |
| Inflammation, Xanthoma | Altered Intercellular Communication | The inflammation destroyed the perimetrial elastic lamina, and the myometrium was deeply infiltrated by the xanthoma cells. | 25027857 |
| Salpingitis, Endometritis | Altered Intercellular Communication | Neither endometritis nor salpingitis was coexistent with the xanthogranulomatous inflammation. | 25027857 |
| Xanthogranulomatous inflammation | Altered Intercellular Communication | The patient was diagnosed as xanthogranulomatous inflammation, most likely arising from the perimetrium. | 25027857 |
| Inflammation, Left ventricular systolic dysfunction, Fluid overload | Altered Intercellular Communication | These are linked to the pathophysiological mechanisms pertaining to left ventricular systolic dysfunction and remodeling, systemic inflammation and volume overload. | 25027873 |
| Inflammation, Anemia, Fluid overload | Altered Intercellular Communication | Increased myocardial remodeling, inflammation, and volume overload are the hallmarks of patients with anemia and HF. | 25027873 |
| methyldopa, Inflammation | Altered Intercellular Communication | Inflammation, among many factors, has been suggested to play an important role in AMD pathogenesis. | 25028103 |
| Refractory anemias, Inflammation, Arthritis | Altered Intercellular Communication | Although patients with RA had higher scores of MRI inflammation and ACPA-positive patients had more BME, the severity of MRI inflammation assessed according to RAMRIS does not accurately differentiate patients with RA from other early arthritis patients. | 25028382 |
| Inflammation, Atrophic | Altered Intercellular Communication | Unlike pepsinogen II and pepsinogen I to II ratio that were affected by the severity of inflammation and atrophy in corpus in all groups, pepsinogen I generally did not change. | 25028655 |
| Inflammation, Fever, CTCAE | Altered Intercellular Communication | From the clinical and laboratory data investigated, 53.33% of the cases presented with fever, and all except one patient presented with increased measures in inflammation tests. | 25029577 |
| Communicable Diseases, Inflammation, Mucosal erosion | Altered Intercellular Communication | The rates of mucosal erosion and active inflammation with the presence of pure coccoid HP infection were 36.0% (9/25) and 44.0% (11/25), respectively, both higher than those without HP infection (13.5%, 10/74; 24.3%, 18/74), while lower than those infected with spiral HP (72.1%, 49/68; 79.4%, 54/68). | 25030866 |
| Communicable Diseases, Inflammation | Altered Intercellular Communication | The quantity of interstitial lymphocyte and inflammation severity were also higher than those without HP infection, while lower than those with spiral HP infection. | 25030866 |
| Synovial joint structure | Altered Intercellular Communication | Crystal presence is an obvious prerequisite for possible crystal induced-inflammation in these tissues, just as similar crystals elicit a gouty inflammatory cascade in synovial joints. | 25031195 |
| Klinefelter Syndrome, Trigonitis | Altered Intercellular Communication | Pseudomembranous trigonitis in a male with Klinefelter syndrome: a case report and evidence of a hormonal etiology. | 25031763 |
| Inflammation, Electrocardiogram: myocardial infarction (finding), Cerebrovascular accident, Peripheral Vascular Diseases, Dental Plaque | Altered Intercellular Communication | Inflammation promotes plaque instability and clinical disease, such as myocardial infarction, stroke and peripheral vascular disease. | 25032953 |
| Tumor necrosis, Inflammation, Atherosclerosis | Altered Intercellular Communication | Activation of CD137 (tumor necrosis factor receptor super family 9) promotes inflammation and disease development in murine atherosclerosis. | 25032953 |
| Inflammation, Gastritis | Altered Intercellular Communication | Although severe gastritis was not observed, activity and inflammation were significantly higher in patients positive for H. pylori than in patients negative for H. pylori. | 25034254 |
| ARCN1 gene, Chronic Obstructive Airway Disease, Tissue injury, Pneumonitis | Altered Intercellular Communication | Cigarette smoking is the main cause of chronic obstructive pulmonary disease (COPD) inducing oxidative stress and local tissue injury, resulting in pulmonary inflammation. | 25034386 |
| vascular inflammations, Vasculitis, CTCAE | Altered Intercellular Communication | Widespread vascular inflammation in a patient with antineutrophil cytoplasmic antibody-associated vasculitis as detected by positron emission tomography. | 25034437 |
| Clinical Events Domain, Coronary Arteriosclerosis | Altered Intercellular Communication | We undertook this study to determine the presence and levels of adhesion molecules as well as other inflammation-related markers and evaluate their invasive angiography findings to compare between patients with CE or atherosclerotic coronary artery disease (CAD). | 25034460 |
| Inflammation, Affection | Altered Intercellular Communication | The presence of high levels of these molecules, along with not uncommon multivessel and extensive coronary affection suggest the participation of subclinical inflammation, which may have an important role in the development of CE. | 25034460 |
| Inflammation, Gastrointestinal perforation | Altered Intercellular Communication | The electrocardiogram, esophagogram, and chest computed tomographic scan commonly revealed pericardial fluid and air and excluded a gastrointestinal perforation in late stage of severe inflammation. | 25034497 |
| Inflammation, Chronic thromboembolic pulmonary hypertension | Altered Intercellular Communication | Chronic thromboembolic pulmonary hypertension (CTEPH) is associated with chronic inflammation but the pathological mechanisms are largely unknown. | 25034560 |
| Inflammation, Fever, CTCAE | Altered Intercellular Communication | The newborn became touch-sensitive, cried a lot, had worsening laboratory test results, and increased inflammation parameters, but no fever was observed. | 25035097 |
| ARCN1 gene | Altered Intercellular Communication | The ratio of sputum-to-serum levels of H2S may provide a useful marker of COPD indicative of obstructive neutrophilic inflammation and of potential ongoing exacerbation. | 25035127 |
| Inflammation, Coronary Arteriosclerosis | Altered Intercellular Communication | Inflammation has been proposed as the main cause for the high risk of atherosclerotic disease in DM II. | 25035341 |
| Inflammation, Fibrous | Altered Intercellular Communication | In this study, we compared markers of inflammation and fibrous repair in plaques from subjects with and without DM II. | 25035341 |
| Rupture, vascular inflammations, atherosclerotic | Altered Intercellular Communication | This study suggests that atherosclerotic plaques in subjects with DM II are more prone to rupture because of impaired repair responses rather than to increased vascular inflammation. | 25035341 |
| Inflammation, Premenstrual syndrome | Altered Intercellular Communication | Association of inflammation markers with menstrual symptom severity and premenstrual syndrome in young women. | 25035435 |
| Inflammation, POLYDACTYLY, POSTAXIAL, WITH PROGRESSIVE MYOPIA, Premenstrual syndrome | Altered Intercellular Communication | Are markers of chronic inflammation associated with menstrual symptom severity and premenstrual syndrome (PMS)? | 25035435 |
| Inflammation, Depression, CTCAE | Altered Intercellular Communication | Chronic inflammation has been implicated in the etiology of depression and other disorders that share common features with PMS, but whether inflammation contributes to menstrual symptom severity and PMS is unknown. | 25035435 |
| Inflammation | Altered Intercellular Communication | 7-Ketocholesterol-induced inflammation signals mostly through the TLR4 receptor both in vitro and in vivo. | 25036103 |
| Inflammation, Lipoproteins | Altered Intercellular Communication | It is suspected of causing chronic inflammation in tissues exposed to oxidized lipoprotein deposits. | 25036103 |
| Inflammation | Altered Intercellular Communication | Our results indicate that 7KCh-induced inflammation is mediated mostly though the TLR4 receptor with some cross-activation of EGFR-related pathways. | 25036103 |
| Inflammation | Altered Intercellular Communication | The 7KCh-induced inflammation also seems to involve a robust ER stress response. | 25036103 |
| Cell Death, Inflammation | Altered Intercellular Communication | Female gene expression was associated with cell death and survival, cell-cell signaling and inflammation. | 25036109 |
| Cell Death, Inflammation | Altered Intercellular Communication | Female gene expression was associated with cell death and survival, cell-cell signaling and inflammation. | 25036109 |
| Inflammation, Dental Plaque | Altered Intercellular Communication | Serum high-sensitivity C-reactive protein (hs-CRP) is a sensitive indicator of inflammation, which is closely related with the progress of plaque formation. | 25036169 |
| Inflammation, Infection associated with prosthesis of left hip joint | Altered Intercellular Communication | (18)F-fluorodeoxy glucose and (18)F fluoride PET for detection of inflammation focus in periprosthetic hip joint infection cases. | 25036230 |
| Myelitis | Altered Intercellular Communication | Cervical spinal cord inflammation was the most common. | 25036359 |
| Inflammation, Dacryocystitis, Bacterial Infections | Altered Intercellular Communication | Dacryocystitis is a common inflammation of the lacrimal sac, usually from an underlying bacterial infection. | 25036545 |
| Pain Distress Question, Inflammation | Altered Intercellular Communication | Pain and function proved to be predictors of the outcome while some measures of inflammation were not. | 25036855 |
| Intraocular inflammation | Altered Intercellular Communication | A 15-year-old Hispanic girl was referred for bilateral intraocular inflammation. | 25037015 |
| Inflammation, Renal function | Altered Intercellular Communication | Baseline plasma concentrations of 25(OH)D and biomarkers of liver and kidney functions and inflammation were measured. | 25037556 |
| Inflammation, Intact | Altered Intercellular Communication | Activation of TLR9 signaling in the pocket epithelium was highly associated with periodontal inflammation and possibly with loss of tissue integrity. | 25037760 |
| HD Term Type, Inflammation | Altered Intercellular Communication | Circulating gelsolin can modulate inflammation and is correlated with HD mortality. | 25039281 |
| Fibrosis Assessment | Altered Intercellular Communication | Mesenchymal stromal cells (MSC), a key component of the stem cell niche in bone marrow and possibly other organs including lung, have been shown to enhance epithelial repair and are effective in preclinical models of inflammation-induced pulmonary fibrosis, but may be profibrotic in some circumstances. | 25039426 |
| Inflammation, Periodontal Diseases | Altered Intercellular Communication | It is important to address this deficiency in our knowledge as neutrophils are the primary immune cell present in the crevicular fluid and oral environment and previous work has suggested that they may be good indicators of overall oral inflammation and periodontal disease severity. | 25040400 |
| Inflammation, Epithelial cell abnormality | Altered Intercellular Communication | Cervical cytological screening results of 8,495 cases in Turkey--common inflammation but infrequent epithelial cell abnormalities? | 25040962 |
| Inflammation, Squamous Epithelial Cells | Altered Intercellular Communication | The most common diagnosis was found to be inflammation, 65.5 % (5,566 out of 8,495), and the least was squamous epithelial abnormalities 0.2% (13 out of 8,495). | 25040962 |
| vinyltriethoxysilane | Altered Intercellular Communication | Median pre-chemotherapy NLR (p = 0.015) and PLR (p = 0.040) were significantly higher in patients with intermediate risk class who developed symptomatic VTE with a twofold increased VTE risk for both inflammation-based markers (NLR: p = 0.022; PLR: p = 0.037) and a worst 1-year VTE-free survival for patients with high NLR or PLR. | 25042739 |
| Inflammation, Thrombosis | Altered Intercellular Communication | Durable polymer has been linked with persistent inflammation of vessel wall and delayed endothelial healing that may increase the risk of late and very late stent thrombosis. | 25043067 |
| Inflammation, Primary malignant neoplasm | Altered Intercellular Communication | Peroxisome proliferator-activated receptors (PPARs) are transcriptional factors involved in several biological processes such as inflammation, cancer growth, progression and apoptosis that are important in lung and upper aero-digestive tract (UADT) cancer outcomes. | 25043640 |
| Inflammation, Epilepsy | Altered Intercellular Communication | Inflammation is a substantial indicator of epilepsy risk. | 25043754 |
| Inflammation, Acute and chronic inflammation | Altered Intercellular Communication | In 23%, the diagnosis was an acute inflammation (presence of granulocytes); in 33%, chronic active inflammation (presence of T lymphocytes); in 33%, low-grade inflammation (presence of CD68 cells, without T lymphocytes); and in 3%, a malignant process. | 25043793 |
| Inflammation, Myocardial | Altered Intercellular Communication | Inflammation and myocardial damage markers influence loss of residual renal function in peritoneal dialysis patients. | 25043805 |
| Inflammation, Cardiovascular system, Cyclophosphamide/Vincristine/Dacarbazine Regimen, Cardiovascular Diseases | Altered Intercellular Communication | Evaluations included measurements of residual renal function, dialysis adequacy parameters, cardiovascular comorbidity, and measurements of biochemical markers of cardiovascular disease (CVD) and inflammation, as well as resting electrocardiography. | 25043805 |
| Retinal Detachment, Inflammation, Macular Edema, Cystoid | Altered Intercellular Communication | There were no postlaser complications such as increased intraocular pressure (IOP), severe inflammation, cystoid macular edema, or retinal detachment. | 25044140 |
| Inflammation, Diabetes Mellitus, Non-Insulin-Dependent | Altered Intercellular Communication | Improvement in vitamin D status does not improve insulin resistance, blood pressure, inflammation or HbA1c, but might increase insulin secretion in patients with established type 2 diabetes. | 25044176 |
| Inflammation, Retinal Diseases, Endothelial dysfunction | Altered Intercellular Communication | Low-grade inflammation and endothelial dysfunction explain the association between retinopathy and left ventricular ejection fraction in men: an 8-year follow-up of the Hoorn Study. | 25044234 |
| Inflammation | Altered Intercellular Communication | Microvascular endothelial dysfunction ([ED] b -4.87 95% CI -13.40 to 3.67) and low-grade inflammation ([LGI] b -5.30 95% CI -13.72 to 3.12) both diminished the association. | 25044234 |
| Inflammation, hepcidin | Altered Intercellular Communication | Patients with inflammation respond less well to treatment with erythropoietin, possibly because the increased production of hepcidin reduces the availability of iron for hematopoiesis. | 25044383 |
| Inflammation, Carcinogenesis | Altered Intercellular Communication | In the CCA-hamsters, STATs expression was gradually increased along the carcinogenesis, especially at 30 days post-infection in which the inflammatory response was markedly observed, showing the correlation between the inflammation and STATs activation. | 25044480 |
| Inflammation, Carcinogenesis, FBN2 wt Allele | Altered Intercellular Communication | STAT3 is the major STAT, which plays roles in the inflammation that contributes to CCA carcinogenesis and progression and may serve as a marker for a poor prognosis of CCA. | 25044480 |
| Inflammation, Injury of kidney | Altered Intercellular Communication | Inflammation is an important factor in renal injury. | 25045297 |
| Refractory anemias, Inflammation | Altered Intercellular Communication | We found no association between REE and disease activity in RA patients, implying that energy metabolism in RA patients might be independent of RA-associated systemic inflammation. | 25045300 |
| Inflammation, Periodontitis, Atherosclerosis, Endothelial dysfunction, physiopathological | Altered Intercellular Communication | Oral inflammation, such as periodontitis, can lead to endothelial dysfunction, accelerated atherosclerosis, and vascular dysfunction. | 25045683 |
| Inflammation, Metabolic Syndrome X | Altered Intercellular Communication | Egg intake during carbohydrate restriction alters peripheral blood mononuclear cell inflammation and cholesterol homeostasis in metabolic syndrome. | 25045936 |
| Inflammation, ETV3 wt Allele | Altered Intercellular Communication | We further sought to determine whether egg yolk intake affects peripheral blood mononuclear cell (PBMC) inflammation and cholesterol homeostasis in MetS, as HDL and its associated lipid transporter ATP-binding cassette transporter A1 (ABCA1) reduce the inflammatory potential of leukocytes through modulation of cellular cholesterol content and distribution. | 25045936 |
| Granulomatous inflammation, Fibrosis Assessment, Infection | Altered Intercellular Communication | Imaging always identified dermal fillers in the oral region, distinguishing among infections, fibrosis, granulomatous inflammation and product migration. | 25046237 |
| Have Autoimmune or Inflammatory Condition | Altered Intercellular Communication | Vitamin D is a multi-functional immune regulator, and a low serum concentration of vitamin D promotes autoimmune inflammation. | 25046415 |
| Inflammation, Atherosclerosis | Altered Intercellular Communication | CD14 is a predictor of inflammation and associated with atherosclerosis. | 25046588 |
| Inflammation, Ischemic, Ischemia | Altered Intercellular Communication | Our findings highlight the key significance of inflammation in the early response to ischaemia during the transitory ischaemic episode. | 25046654 |
| Vaginitis | Altered Intercellular Communication | They were also more likely to show microscopic evidence of vaginal inflammation and vaginitis. | 25046810 |
| Inflammation | Altered Intercellular Communication | AMP-activated protein kinase (AMPK) inhibits chondrocyte procatabolic responses to inflammation and biomechanical injury. | 25047750 |
| Osteomyelitis, Inflammation, Bone necrosis | Altered Intercellular Communication | Patient records were searched for inflammatory conditions including unspecified inflammation, osteomyelitis, osteonecrosis due to drugs, and other osteonecrosis. | 25047929 |
| Osteomyelitis, Inflammation, Bone necrosis | Altered Intercellular Communication | Patient records were searched for inflammatory conditions including unspecified inflammation, osteomyelitis, osteonecrosis due to drugs, and other osteonecrosis. | 25047929 |
| Inflammation, Necrosis | Altered Intercellular Communication | Pathological examination revealed the presence of necrosis and chronic inflammation. | 25048049 |
| Inflammation | Altered Intercellular Communication | In conclusion, underweight status after treatment may be a poor prognostic factor in patients with advanced-stage ovarian cancer, which accompanies increased host inflammation and decreased immunity. | 25050383 |
| Degenerative polyarthritis, Inflammation | Altered Intercellular Communication | Impact of Supplementation with Curcuminoids on Systemic Inflammation in Patients with Knee Osteoarthritis: Findings from a Randomized Double-Blind Placebo-Controlled Trial. | 25050518 |
| Degenerative polyarthritis, Inflammation | Altered Intercellular Communication | Osteoarthritis (OA) is a degenerative joint disease associated with inflammation. | 25050518 |
| Autoimmune Diseases, Rheumatoid Arthritis, Inflammation | Altered Intercellular Communication | Rheumatoid arthritis a chronic inflammatory autoimmune disease with inflammation of the joint, leading to damage of bone and surrounding cartilage. | 25050521 |
| Inflammation, Cardiovascular Diseases | Altered Intercellular Communication | Cardiovascular disease is the leading cause of mortality in hemodialysis patients and is associated with chronic inflammation. | 25051062 |
| Inflammation, Heart failure, Sarcopenia, Myocardial fibrosis, Hypertensive disease | Altered Intercellular Communication | In order to establish the prognostic value of age-related pathogenesis and the development of heart failure related to lipid peroxidation, endogenous subclinical inflammation, apoptosis, sarcopenia, interstitial myocardial fibrosis in the risk of mortality and survival rates, for the first time the results of echocardiography, enzyme immunoassay, bioimpedansmetry with the scale of the Seattle model of heart failure performed in 84 elderly patients with arterial hypertension stage II (middle age 68,3 +/- 1,8 years) were compared. | 25051770 |
| Inflammation, Periprosthetic osteolysis | Altered Intercellular Communication | Wear debris-induced inflammation is considered to be the main cause for periprosthetic osteolysis in total hip replacements (THR). | 25051953 |
| Osteolysis | Altered Intercellular Communication | Our findings indicate that wear particles of different chemical composition induced similar inflammatory responses, which suggests that particle size and load might be more important than the wear particle composition in periprosthetic inflammation and osteolysis. | 25051953 |
| Airway structure, Allergic, Asthma | Altered Intercellular Communication | Pollen exposure of allergic subjects with asthma causes increased nitric oxide (NO) in exhaled air (FENO) suggestive of increased airway inflammation. | 25052059 |
| Inflammation, Asthma | Altered Intercellular Communication | The aim of the present investigation was to analyze the relationship between central and peripheral components of FENO to clarify the distribution of pollen induced inflammation in asthma. | 25052059 |
| Allergic asthma, Airway structure | Altered Intercellular Communication | The findings may indicate that subjects with allergic asthma have airway inflammation without alveolar involvement outside the pollen season and pollen exposure causes a further increase of airway inflammation and in a few subjects obstruction of intra acinar airways causing impeded back diffusion. | 25052059 |
| Inflammation, Sacroiliac joint structure, Spondylarthritis | Altered Intercellular Communication | The aim of this study was to describe the use of (99m)Tc-anti-TNF-a scintigraphy for detecting inflammation of the sacroiliac joints in a patient with non-radiographic axial spondyloarthritis. | 25052689 |
| Inflammation, Morning stiffness - joint, Uveitis | Altered Intercellular Communication | A 47-year-old female patient, non-smoker and non-drinker, complained of a low back pain inflammation, which began 4 years before her condition have exacerbated to morning stiffness and anterior uveitis in the last 6 months. | 25052689 |
| Inflammation, Nerve Degeneration | Altered Intercellular Communication | Advanced glycation end products (AGEs) accumulate in T2DM, resulting in inflammation, oxidative stress, and protein cross-linking, which are known contributors to neurodegeneration. | 25053588 |
| Airway structure, ARCN1 gene | Altered Intercellular Communication | Characterization of airway inflammation in patients with COPD using fractional exhaled nitric oxide levels: a pilot study. | 25053884 |
| Airway structure, ARCN1 gene, Chronic Obstructive Airway Disease | Altered Intercellular Communication | To characterize fractional exhaled nitric oxide (FeNO) levels that may be indicative of Th2-mediated airway inflammation in patients with chronic obstructive pulmonary disease (COPD). | 25053884 |
| Airway structure, ARCN1 gene | Altered Intercellular Communication | Since FeNO is useful for identifying patients with airway inflammation who will have a beneficial response to treatment with an inhaled corticosteroid, these data may have important implications for the management of COPD patients. | 25053884 |
| Inflammation, Carcinogenesis, Neoplasms | Altered Intercellular Communication | Mounting evidence supports that chronic inflammation (such as chronic overactivation of IL-1 system) is a crucial event in carcinogenesis and tumor progression. | 25054228 |
| Glioblastoma Multiforme Pathway | Altered Intercellular Communication | While much attention is paid to specific anti-tumor immunity, little is known about the role of chronic inflammation/innate immunity in glioma pathogenesis. | 25054228 |
| Carcinoma of lung, Toxic effect | Altered Intercellular Communication | Inflammation-related genetic variants predict toxicity following definitive radiotherapy for lung cancer. | 25054431 |
| Esophagitis, Radiation Pneumonitis | Altered Intercellular Communication | We therefore conducted a pathway-based analysis to identify inflammation-related single-nucleotide polymorphisms associated with radiation-induced pneumonitis or esophagitis. | 25054431 |
| Toxic effect | Altered Intercellular Communication | We concluded that inflammation-related genetic variants could contribute to the development of radiation-induced toxicities. | 25054431 |
| Dose-Limiting, Toxic effect | Altered Intercellular Communication | However, radiation-induced toxicities (pneumonitis/esophagitis) are common dose-limiting inflammatory conditions. | 25054431 |
| Inflammation, neurological complication | Altered Intercellular Communication | H1N1 vaccination can result in important neurological complications probably secondary to post-vaccination inflammation. | 25054980 |
| Pain Distress Question, Inflammation, Neoplasms, Malignant neoplasm of skin, Perineural spread, Ulceration, CTCAE | Altered Intercellular Communication | Itch and pain associated with skin cancer at the time of excision ranked on an 11-point (score range, 0-10) numerical visual analog scale and histopathologic analysis for each neoplasm (assessment of the amount and type of inflammation, ulceration, perineural invasion, and depth of invasion). | 25055194 |
| Pain Distress Question, Inflammation | Altered Intercellular Communication | Pain intensity was significantly associated with the degree of inflammation (mild or none vs moderate or marked; P < .001), presence of neutrophils in the inflammatory infiltrate (predominantly mononuclear vs mixed or neutrophilic; P = .003), presence of eosinophils (present vs absent; P = .007), ulceration (yes vs no; P = .003), perineural invasion (yes vs no; P < .001), depth of invasion (P = .001), and largest diameter length of skin lesion (P < .003). | 25055194 |
| Inflammation | Altered Intercellular Communication | Several published studies suggest that physical activity is a beneficial nonpharmacological intervention to reduce chronic inflammation. | 25055246 |
| Inflammation, Atherosclerosis | Altered Intercellular Communication | The hallmark of atherosclerosis is chronic inflammation in the vessel wall. | 25056169 |
| Inflammation | Altered Intercellular Communication | Midkine, a multifunctional cytokine, fulfils different roles in inflammation and promotion of neoangiogenesis. | 25056169 |
| Inflammation, Hypertension, CTCAE, Traumatic injury | Altered Intercellular Communication | The glomerulus contains well-developed capillaries, which are at risk of injury due to high hydrostatic pressure, hyperfiltration, hypertension and inflammation. | 25056826 |
| Inflammation, Carcinogenesis | Altered Intercellular Communication | Chronic inflammation is known to be one of the main steps in carcinogenesis. | 25057172 |
| Inflammation, Primary malignant neoplasm | Altered Intercellular Communication | Identification of those with chronic inflammation may help identify subjects at risk of cancer. | 25057172 |
| Inflammation, Atherosclerosis | Altered Intercellular Communication | A crucial role for CDC42 in senescence-associated inflammation and atherosclerosis. | 25057989 |
| vascular inflammations, Atherosclerosis | Altered Intercellular Communication | Risk factors for atherosclerosis accelerate the senescence of vascular endothelial cells and promote atherogenesis by inducing vascular inflammation. | 25057989 |
| Inflammation | Altered Intercellular Communication | We identified CDC42 signaling as a mediator of chronic inflammation associated with endothelial senescence. | 25057989 |
| Inflammation, Dental Plaque, atherosclerotic | Altered Intercellular Communication | Likewise, endothelial-specific deletion of Cdc42 significantly attenuated chronic inflammation and plaque formation in atherosclerotic mice. | 25057989 |
| Inflammation | Altered Intercellular Communication | While inhibition of NF-kB suppressed the pro-inflammatory responses in acute inflammation, the influence of Cdc42 deletion was less marked. | 25057989 |
| Inflammation | Altered Intercellular Communication | These findings indicate that the CDC42 pathway is critically involved in senescence-associated inflammation and could be a therapeutic target for chronic inflammation in patients with age-related diseases without compromising host defenses. | 25057989 |
| Inflammation | Altered Intercellular Communication | Repetitive microtrauma within the pes anserinus may lead to chronic inflammation and later result in development of degenerative changes in this region. | 25058106 |
| Inflammation, FBN2 wt Allele | Altered Intercellular Communication | CCA arises via chronic inflammation which may be associated with autoantibodies production. | 25058392 |
| allergic inflammation | Altered Intercellular Communication | Hence, the activation of apical TLR9 on IECs, potentially by microbiota-derived signals, may play an important role in the prevention of allergic inflammation. | 25058467 |
| Inflammation, Psoriasis, Eczema | Altered Intercellular Communication | We observed a strong clinical inflammation with a mixed psoriasis and eczema phenotype in histology. | 25058585 |
| Inflammation, talc | Altered Intercellular Communication | Predictive value of systemic and local inflammation parameters in talc pleurodesis assessment. | 25059234 |
| Fibrosis Assessment | Altered Intercellular Communication | Then, we assessed the efficacy of MR16-1 in tight skin-1 (Tsk-1) mice, an inflammation-independent model of skin fibrosis. | 25059342 |
| Inflammation, Thrombosis | Altered Intercellular Communication | The safety of drug-eluting stents (DES) vs. bare metal stents (BMS) in the perioperative setting, a heightened state of inflammation and thrombosis is not well defined. | 25059742 |
| Inflammation, Dissection of aorta, Data types - Address | Altered Intercellular Communication | Inflammation has been reported to be associated with aortic dissection (AD), from the development to the prognosis of AD. | 25059935 |
| Inflammation | Altered Intercellular Communication | The inflammation associated with DNM may involve the heart, which produces acute changes in the electrocardiogram (ECG). | 25060009 |
| Inflammation, Infection caused by Helicobacter pylori | Altered Intercellular Communication | Pepsinogen levels in plasma are increased by inflammation in the gastric mucosa, including inflammation resulting from Helicobacter pylori infection. | 25060199 |
| Inflammation, Allergic rhinitis (disorder) | Altered Intercellular Communication | Allergic fungal rhinosinusitis (AFRS) is a disease demonstrating substantial eosinophilic inflammation and characteristic radiographic bony erosion/expansion. | 25060295 |
| Hemorrhage | Altered Intercellular Communication | Physical, histological and endoscopic examination revealed neither focus of active bleeding nor signs of active inflammation. | 25060698 |
| Inflammation, Myocardial Ischemia | Altered Intercellular Communication | Reciprocal effects of systemic inflammation and brain natriuretic peptide on adiponectin biosynthesis in adipose tissue of patients with ischemic heart disease. | 25060790 |
| Inflammation, Myocardial Ischemia | Altered Intercellular Communication | To explore the role of systemic inflammation in the regulation of adiponectin levels in patients with ischemic heart disease. | 25060790 |
| Inflammation, Atherosclerosis | Altered Intercellular Communication | This study demonstrates the regional variability in the responsiveness of human adipose tissue to systemic inflammation and suggests that BNP (not systemic inflammation) is the main driver of circulating adiponectin in patients with advanced atherosclerosis even in the absence of HF. | 25060790 |
| Airway structure | Altered Intercellular Communication | Asthma management in an outpatient setting is best accomplished by clinical evaluation coupled with spirometry and symptom evaluation, but these assessments do not provide information about airway inflammation. | 25060819 |
| Airway structure, Asthma | Altered Intercellular Communication | Exhaled nitric oxide (fraction of exhaled nitric oxide [FeNO]) measures T-helper cell type 2-mediated airway inflammation and may be a useful adjunct in asthma management. | 25060819 |
| Airway structure | Altered Intercellular Communication | Without FeNO, the clinician's assessment of airway inflammation was incorrectly classified in 50% of subjects. | 25060819 |
| Airway structure, Asthma | Altered Intercellular Communication | Measurement of FeNO augments routine clinical assessment of asthma by measuring airway inflammation. | 25060819 |
| Inflammation, Diabetes Mellitus, Cardiovascular Diseases | Altered Intercellular Communication | Inflammation and oxidative stress appear to play some role in the mechanisms underlying aging, diabetes, cardiovascular disease, and other complications of diabetes. | 25060886 |
| Intraocular inflammation | Altered Intercellular Communication | Control of intraocular inflammation, defined as complete lack of clinical and angiographic signs of inflammatory activity, was achieved in 16 of 24 patients (67%). | 25061107 |
| Inflammation, Malignant Neoplasms | Altered Intercellular Communication | The association between cardiopulmonary reserve and inflammation was tested by multivariable regression analysis with covariates including anaerobic threshold (AT) and malignancy. | 25061264 |
| Inflammation, Heart failure | Altered Intercellular Communication | Poor exercise capacity in patients without a diagnosis of heart failure is independently associated with markers of inflammation. | 25061264 |
| Inflammation | Altered Intercellular Communication | These observations suggest that preoperative inflammation associated with impaired cardiorespiratory performance may contribute to the pathophysiology of postoperative outcome. | 25061264 |
| Inflammation of orbit | Altered Intercellular Communication | Thus, the pathogenesis of GD and GO may correlate with different genetic backgrounds, which has been confirmed by studies of correlations between GO and polymorphisms in cytokines involved in orbit inflammation. | 25061884 |
| Inflammation | Altered Intercellular Communication | These findings suggest that inflammation plays a possible role in the pathophysiology of RHTN. | 25061978 |
| Inflammation, Metabolic Syndrome X, Cyclophosphamide/Vincristine/Dacarbazine Regimen, ETV3 wt Allele, Diabetes Mellitus | Altered Intercellular Communication | The Metabolic Syndrome, (MetS) a global epidemic, is a state of low grade chronic inflammation and confers an increased risk for diabetes and CVD. | 25063948 |
| Inflammation, Cyclophosphamide/Vincristine/Dacarbazine Regimen, ETV3 wt Allele, Diabetes Mellitus | Altered Intercellular Communication | Thus, we make the novel observation that sCD14 reflects increased monocyte TLR4 protein and activity in nascent MetS and by contributing to increased cellular inflammation could explain, in part, the increased risk for diabetes and CVD. | 25063948 |
| Carcinogenic Chlorinated Hydrocarbon, Fibrosis Assessment, Inflammation, Fatty degeneration | Altered Intercellular Communication | Pirfenidone for two years benefits CHC patients and improves inflammation, fibrosis and steatosis in higher number of patients as previously shown for 12-months treatment with PFD. | 25064094 |
| Degenerative polyarthritis, Inflammation | Altered Intercellular Communication | Emerging evidence indicates that low-grade inflammation is part of the clinical picture of OA and that there is a need to identify soluble biomarkers of ongoing inflammation in the joint from a translational aspect. | 25065008 |
| Vasculitis, Vasculitis, CTCAE | Altered Intercellular Communication | Cutaneous vasculitis (CV) encompasses a wide group of entities characterized by inflammation of skin blood vessels. | 25065012 |
| Inflammation, Carcinogenesis | Altered Intercellular Communication | Systemic inflammation plays an important role in the initiation, promotion, and progression of lung carcinogenesis. | 25065540 |
| Inflammation, Fibrosis Assessment, Fatty degeneration | Altered Intercellular Communication | Expression analysis of miRNAs was performed by qPCR, and they were analysed for differences between patient gender and age, genotypes, stage of fibrosis, grade of inflammation, serum level of liver enzymes, serum viral load, the presence of steatosis and mode of transmission. | 25065618 |
| Inflammation, Chronic Kidney Diseases, Obesity | Altered Intercellular Communication | To investigate the relative associations of renal function, obesity, and inflammation with serum leptin levels in children with chronic kidney disease (CKD). | 25066063 |
| Inflammation, Diabetic Retinopathy | Altered Intercellular Communication | Chronic inflammation has a role in the pathogenesis of diabetic retinopathy. | 25066224 |
| Communicable Diseases, Inflammation | Altered Intercellular Communication | Infection with intracellular organisms may incite chronic inflammation. | 25066224 |
| Inflammation | Altered Intercellular Communication | MRI examination revealed no changes in the painful region in a majority of patients with AO, suggesting that inflammation was not present. | 25068217 |
| Airway structure | Altered Intercellular Communication | In conclusion, sputum IL-6 and IL-8 may play a role in neutrophilic airway inflammation seen in patients undergoing HSCT. | 25068427 |
| Inflammation, Hypertension, CTCAE | Altered Intercellular Communication | Further studies should determine if chronic, dysregulated inflammation may accelerate hypertension in this population. | 25070128 |
| Uremia, Inflammation, Chronic Kidney Diseases, Vascular lesions | Altered Intercellular Communication | Our results indicate that sclerostin levels are elevated in CKD patients and are associated with inflammation, vascular lesions, uremia and (potentially) mortality. | 25070604 |
| Inflammation, Necrosis | Altered Intercellular Communication | The pancreas was divided into head, body, and tail, and each segment was classified according to image features: pattern 1, normal; pattern 2, mild inflammation; and pattern 3, necrosis. | 25070771 |
| Inflammation, Juvenile polyposis syndrome | Altered Intercellular Communication | Serum C-reactive protein (CRP) is a general marker of inflammation, and recent studies suggest that measurement of CRP in synovial fluid may be a more accurate method for diagnosing periprosthetic joint infection (PJI). | 25070920 |
| Inflammation, Bacterial Infections | Altered Intercellular Communication | Upregulated CD64 expression on neutrophils is the most useful marker for acute bacterial infections and systemic inflammation. | 25071912 |
| polychondritis, Orbital Pseudotumor | Altered Intercellular Communication | This led to rapid improvement in orbital symptoms and signs, and a diagnosis of specific orbital inflammation secondary to relapsing polychondritis was made. | 25072220 |
| Inflammation, Primary malignant neoplasm | Altered Intercellular Communication | Intraoperative near-infrared imaging can distinguish cancer from normal tissue but not inflammation. | 25072388 |
| Vasculitic Ulcer | Altered Intercellular Communication | Thirty-four patients affected by other than vascular ulcers, neoplastic or inflammatory conditions, were excluded. | 25072681 |
| Inflammation, Pleural effusion disorder | Altered Intercellular Communication | The capillary leaks secondary to inflammation result in a larger pleural pore-size, which allows the large-sized lipoproteins to accumulate in exudative pleural effusions. | 25072840 |
| Inflammation, Nephritis | Altered Intercellular Communication | Low pre-transplant serum MBL levels are associated with more severe inflammation and increased apoptosis in early surveillance renal allograft biopsies suggesting that MBL modulates renal inflammation after transplantation. | 25073029 |
| Inflammation, Fever, CTCAE, Autosomal recessive inheritance, Brucellosis, Familial Mediterranean Fever | Altered Intercellular Communication | Familial Mediterranean fever (FMF) is an autosomal recessive disease characterized by recurrent episodes of fever and serosal, synovial, or cutaneous inflammation, caused by a dysfunction of pyrin as a result of mutation within the MEFV gene. | 25073670 |
| Communicable Diseases, Inflammation | Altered Intercellular Communication | Although tattooing is widely used and relatively safe, the presented case indicates the risk of infection or inflammation by tattooing. | 25073671 |
| Inflammation, Fatty degeneration | Altered Intercellular Communication | Elevated ferritin levels pointed to a higher incidence of steatosis (48 vs. 10% for normal ferritin, p < 0.001) and inflammation (87 vs. 62% for normal ferritin, p = 0.004). | 25074257 |
| Inflammation, Fibrosis Assessment, Fatty degeneration | Altered Intercellular Communication | Elevated AST and ferritin levels were associated with steatosis, inflammation and fibrosis on liver biopsies. | 25074257 |
| Inflammation, Chronic Kidney Diseases | Altered Intercellular Communication | We evaluated circulating S100A12 and sRAGE in relation to clinical characteristics, nutritional status, inflammation and mortality risk in chronic kidney disease (CKD) Stage 5 patients starting on dialysis. | 25074436 |
| Inflammation, Comorbidity | Altered Intercellular Communication | Furthermore, S100A12 correlated with high-sensitivity C-reactive protein (hsCRP) levels (r = 0.53; P < 0.001) and a 1-SD higher level of S100A12 associated with increased all-cause mortality risk (hazard ratio 1.32, 95% confidence interval 1.01-1.73) after adjustment for age, sex, comorbidity, nutritional status and inflammation (hsCRP). | 25074436 |
| Inflammation, Chronic Kidney Diseases | Altered Intercellular Communication | In CKD 5 patients, an increased concentration of S100A12 are associated with inflammation, comorbidities and increased mortality risk whereas no such associations were observed for sRAGE. | 25074436 |
| Inflammation | Altered Intercellular Communication | Oxidative stress and systemic inflammation as modifiers of cardiac autonomic responses to particulate air pollution. | 25074558 |
| Inflammation, Autonomic nervous system disorders | Altered Intercellular Communication | The role of oxidative stress and systemic inflammation on the association between personal exposures to ambient fine particulate matter <= 2.5 mm in diameter (PM2.5) and cardiac autonomic dysfunction, indicated by reduction in heart rate variability (HRV), has not been examined. | 25074558 |
| Inflammation | Altered Intercellular Communication | MRI-detected subclinical joint inflammation is associated with radiographic progression. | 25074691 |
| Inflammation, Arthritis | Altered Intercellular Communication | We recently demonstrated that MRI inflammation is prevalent in clinically non-swollen joints of early arthritis patients. | 25074691 |
| Inflammation, Joint swelling | Altered Intercellular Communication | Of all non-swollen joints (n=932), 232 joints (26%) had subclinical inflammation (>=1 MRI-inflammation feature present). | 25074691 |
| Inflammation | Altered Intercellular Communication | Radiographic progression was present in 4% of non-swollen joints with subclinical inflammation compared to 1% of non-swollen joints without subclinical inflammation (relative risks (RR) 3.5, 95% CI 1.3 to 9.6). | 25074691 |
| Inflammation | Altered Intercellular Communication | Radiographic progression was infrequent, but joints with subclinical inflammation had an increased risk of radiographic progression within year 1. | 25074691 |
| Inflammation | Altered Intercellular Communication | This demonstrates the relevance of MRI-detected subclinical inflammation. | 25074691 |
| Inflammation, Low muscle mass | Altered Intercellular Communication | Old age, comorbidities, protein-energy wasting, physical inactivity, low albumin, and inflammation associated with low muscle strength, but not with low muscle mass (multivariate ANOVA interactions). | 25074839 |
| Inflammation, Low muscle mass | Altered Intercellular Communication | Low muscle strength was more strongly associated with aging, protein-energy wasting, physical inactivity, inflammation, and mortality than low muscle mass. | 25074839 |
| Carcinogenesis, Neoplasms, prostatitis | Altered Intercellular Communication | There are accumulating epidemiological, experimental, and genetic data supporting that prostate inflammation may contribute to prostate carcinogenesis, and several inflammatory-related molecules have been linked to tumorigenesis and prognosis in several tumors. | 25075566 |
| Chronicity, Inflammation | Altered Intercellular Communication | A peritoneal biopsy showed morphological changes of acute inflammation and chronicity. | 25076189 |
| Inflammation, Pain Distress Question | Altered Intercellular Communication | Of the 30 patients, 25 have had no postoperative problems and five had mild inflammation, of which three patients developed intractable pain and underwent soft-tissue reduction. | 25076228 |
| Inflammation, Neoplasms, Diabetes Mellitus | Altered Intercellular Communication | Animal models have shown that hyperinsulinemic state underlying diabetes promotes tumor formation through stimulation of insulin-IGF-1 pathway; a possible role of inflammation is also proposed. | 25076332 |
| Inflammation, Metabolic Syndrome X, Obesity | Altered Intercellular Communication | Obesity and insulin resistance are hallmarks of the metabolic syndrome, which is associated with low-grade chronic inflammation. | 25076422 |
| Inflammation | Altered Intercellular Communication | Therefore, the circulating clusterin level may be a surrogate marker for obesity-associated systemic inflammation. | 25076422 |
| Glucose Metabolism Disorders, Inflammation, Cardiovascular Diseases, Communicable Diseases, Mood Disorders, Weight Gain, MS gene | Altered Intercellular Communication | Vitamin D deficiency has been known as a global health problem and there were reported moderate to strong inverse associations between 25(OH) D concentrations and cardiovascular diseases, serum lipid concentrations, inflammation, glucose metabolism disorders, weight gain, infectious diseases, multiple sclerosis, mood disorders, declining cognitive function, impaired physical functioning, and all-cause mortality. | 25076695 |
| Inflammation, Neoplasms, Colorectal Carcinoma, Ulcerative Colitis | Altered Intercellular Communication | It appears that tumor suppressor gene-VEGF axis have dual role on immune response in inflammation of UC and tumor growth and progression of CRC. | 25076849 |
| Inflammation, Hypothermia due to exposure, Necrosis | Altered Intercellular Communication | He developed muscarinic and nicotinic symptoms with hypothermia, inflammation in the site of the pesticide injection without necrosis. | 25078103 |
| Sacroiliitis, vascular inflammations, Arthritis, Psoriatic, Atherosclerosis | Altered Intercellular Communication | Psoriatic arthritis and sacroiliitis are associated with increased vascular inflammation by 18-fluorodeoxyglucose positron emission tomography computed tomography: baseline report from the Psoriasis Atherosclerosis and Cardiometabolic Disease Initiative. | 25078679 |
| Sacroiliitis, vascular inflammations, PROS1 gene | Altered Intercellular Communication | Because the presence of sacroiliitis may portend more severe PsA, we hypothesized that sacroiliitis defined by computed tomography (CT) would be associated with increased vascular inflammation defined by 18-fluorodeoxyglucose-positron emission tomography/computed tomography (FDG-PET/CT), which is an established measure of CVD. | 25078679 |
| PROS1 gene, vascular inflammations, Sacroiliitis | Altered Intercellular Communication | Linear regression (with b-coefficients (b) and P-values reported for PsA and sacroiliitis) was used to adjust for CVD risk factors to determine associations of PsA or sacroiliitis with vascular inflammation. | 25078679 |
| Sacroiliitis, vascular inflammations | Altered Intercellular Communication | Vascular inflammation (measured as SUVmax) was greater (P < 0.001) in patients with sacroiliitis (mean +- SD = 7.33 +- 2.09) defined by CT compared to those without sacroiliitis (6.39 +- 1.49, P = 0.038). | 25078679 |
| PROS1 gene, Inflammation, Sacroiliitis | Altered Intercellular Communication | There were associations between PsA and aortic inflammation (b = 0.124, P < 0.001) and between sacroiliitis and aortic inflammation (b = 0.270, P < 0.001) after adjusting for CVD risk factors. | 25078679 |
| Sacroiliitis, vascular inflammations, Cyclophosphamide/Vincristine/Dacarbazine Regimen, PROS1 gene | Altered Intercellular Communication | Sacroiliitis predicted vascular inflammation beyond PsA and CVD risk factors (kh2 = 124.6, P < 0.001). | 25078679 |
| Sacroiliitis, vascular inflammations, Sacroiliac joint structure | Altered Intercellular Communication | Sacroiliitis is associated with increased vascular inflammation detected by FDG-PET/CT, suggesting that sacroiliac joint disease may identify patients at greater risk for CVD. | 25078679 |
| Inflammation | Altered Intercellular Communication | Upon histological examination, the degree of inflammation was subjectively graded as mild, moderate, or severe by 2 separate investigators. | 25079201 |
| Inflammation, Eczema of nipple, Data types - Address | Altered Intercellular Communication | Although nipple eczema may accompany AD, we found no definite differences in the degree or pattern of inflammation and cytokine expression level regardless of whether AD was present or not. | 25079201 |
| palladium, Gingivitis | Altered Intercellular Communication | In summary, this investigation supports salivary levels of IL-1ra and IL-6 as potential indicators for PD changes during induced gingival inflammation. | 25079398 |
| Inflammation, physiopathological | Altered Intercellular Communication | The detected transcriptional abnormalities also support robust inflammation, profound extracellular matrix impairments, broad metabolic dysfunction, aberrant oxidative stress, DNA damage, and cell death. | 25079797 |
| Inflammation | Altered Intercellular Communication | The data suggest that early treatment with prednisolone may modulate not only inflammation but also autoimmunity-associated pathogenetic mechanisms. | 25079933 |
| Inflammation, Colitis | Altered Intercellular Communication | Administration of the butyrate (a fermentation product of gut microbes) increases intestinal VDR expression and suppresses inflammation in a colitis model. | 25080448 |
| Inflammation, Anemia | Altered Intercellular Communication | EPO is a sensitive indicator of iron status across gestation, is not affected by systemic inflammation, and may better predict risk of anemia at term. | 25080540 |
| Inflammatory abnormality of the eye | Altered Intercellular Communication | Long-standing prosthetic eye wearing induces ocular surface inflammation. | 25081289 |
| Inflammation | Altered Intercellular Communication | Limited data exist on the presence and function of immune-competent cells in chronic tendinopathic tendons and their potential role in inflammation and tissue healing as well as in predicting long-term outcome. | 25081311 |
| Inflammation, Carcinogenesis, Nasopharyngeal carcinoma | Altered Intercellular Communication | Inflammation has been demonstrated to be widely involved in the carcinogenesis of nasopharyngeal carcinoma (NPC). | 25081376 |
| Inflammation, Coronary heart disease | Altered Intercellular Communication | Genetic and environmental influences on the prospective correlation between systemic inflammation and coronary heart disease death in male twins. | 25082230 |
| Cessation of life, Inflammation, Coronary heart disease, Choline Dehydrogenase, Mitochondrial | Altered Intercellular Communication | Because of lack of evidence, we aimed to examine to what degree low-grade systemic inflammation and coronary heart disease (CHD) death shared common genetic and environmental substrates. | 25082230 |
| Inflammation | Altered Intercellular Communication | Low-grade systemic inflammation, measured by IL-6, and long-term CHD death share moderate genetic substrates that augment both traits. | 25082230 |
| Inflammation, Exudate | Altered Intercellular Communication | Specimens with conspicuous inflammation showed narrowed portions in the nasolacrimal duct, in which severe inflammation and exudate in the lumen was observed. | 25082889 |
| Inflammatory abnormality of the eye | Altered Intercellular Communication | Topical cyclosporine a 1% for the treatment of chronic ocular surface inflammation. | 25083780 |
| Inflammation, Periodontitis | Altered Intercellular Communication | The results of this study confirm the association between periodontal inflammation and increased cardiovascular risk shown by impaired vascular health in case of severe periodontitis. | 25084111 |
| Tumor necrosis, Inflammation | Altered Intercellular Communication | The decoy receptor 3 (DcR3) is a member of the tumour necrosis factor (TNF) receptor superfamily and may regulate inflammation. | 25084482 |
| Inflammation, Traumatic injury | Altered Intercellular Communication | Further, inflammation has been implicated in the long-term progression and severity of HI injury. | 25084519 |
| Communicable Diseases, Inflammation | Altered Intercellular Communication | Recently, inter-alpha inhibitor proteins (IAIPs) have been shown to attenuate inflammation in models of systemic infection. | 25084519 |
| Hyperlipidemia, Primary malignant neoplasm, Inflammation | Altered Intercellular Communication | Since hyperlipidemia, inflammation, insulin resistance and obesity increase breast cancer risk, elevating GH may serve to exacerbate cancer progression. | 25085903 |
| Inflammation | Altered Intercellular Communication | BMEP regions showed significantly increased bone density and structures as well as perfusion measures, suggesting bone remodeling and active inflammation. | 25086074 |
| Inflammation, Inflammatory disorder | Altered Intercellular Communication | Visfatin correlates with inflammation and its levels in peripheral blood are associated with some inflammatory diseases. | 25086268 |
| Inflammation, Acute Cholecystitis | Altered Intercellular Communication | Thus, high plasma levels of visfatin are associated with systemic inflammation, and may independently predict conversion of laparoscopic cholecystectomy to open surgery in acute cholecystitis. | 25086268 |
| Diabetes Mellitus, Non-Insulin-Dependent, Obesity, Hypothalamic structure | Altered Intercellular Communication | These results reveal an atypical, mRNA metabolism-driven hypothalamic nuclear factor-kB activation, a mechanism that links obesity as well as aging to hypothalamic inflammation and ultimately to type 2 diabetes. | 25086906 |
| Neuromyelitis Optica, Extrapontine Myelinolysis, Inappropriate ADH Syndrome | Altered Intercellular Communication | [Case of neuromyelitis optica spectrum disorder associated with central pontine and extrapontine myelinolysis preceded by syndrome of inappropriate antidiuretic hormone secretion]. | 25087556 |
| Chronic lymphocytic inflammation, Pontine structure, Swelling, Clippers | Altered Intercellular Communication | [Chronic lymphocytic inflammation with pontine perivascular enhancement responsive to steroids (CLIPPERS) associated with swelling in the brainstem: a case report]. | 25087561 |
| Chronic lymphocytic inflammation, Pontine structure, Clippers | Altered Intercellular Communication | Chronic lymphocytic inflammation with pontine perivascular enhancement responsive to steroids (CLIPPERS) is a rare central nervous system inflammatory disease characterized by the punctate gadolinium enhancement peppering the pons and the cerebellar peduncles as neuroimaging. | 25087561 |
| Inflammation | Altered Intercellular Communication | Dietary and endogenous fatty acids could play a role in low-grade inflammation. | 25087591 |
| Inflammation, Dysplasia, Abnormal Epithelial Cell | Altered Intercellular Communication | Biopsies are classified as indefinite for dysplasia (IND) when the significance of epithelial abnormalities is uncertain due to inflammation or sampling. | 25087917 |
| Cerebral Infarction | Altered Intercellular Communication | In light of the increased risk of further progression of cerebral infarction, we decided to perform surgical revascularization in spite of her active inflammatory condition. | 25088171 |
| Inflammation, Cyclophosphamide/Vincristine/Dacarbazine Regimen, Cardiovascular Diseases | Altered Intercellular Communication | Inflammation is one possible mechanism underlying the associations between mental disorders and cardiovascular diseases (CVD). | 25088287 |
| SYN2 gene | Altered Intercellular Communication | Synapsin II (SynII), a neuron specific phosphoprotein plays a major role in synaptogenesis and neurotransmitter release. | 25088614 |
| Inflammation, Asthma | Altered Intercellular Communication | Vitamin D is hypothesized to have some roles in innate and adaptive immunity, inflammation reduction, and remodeling; therefore, it is supposed to affect the asthma phenotype, severity, and response to inhaled corticosteroid (ICS). | 25091714 |
| Inflammation | Altered Intercellular Communication | Thus, glycans may potentially be triggering or perpetuating inflammation. | 25092526 |
| Cardiac Arrest, Inflammation | Altered Intercellular Communication | The kynurenine pathway (KP) is the major route of tryptophan (TRP) catabolism and is activated by inflammation and after cardiac arrest in animals. | 25092787 |
| Impaired cognition | Altered Intercellular Communication | The data suggest that ammonia toxicity and HE are associated with premature astrocyte senescence, which may impair neurotransmission and contribute to persistence of cognitive disturbances after resolution of episodes of overt HE. | 25092802 |
| Decreased glomerular filtration rate, Inflammation, Anemia | Altered Intercellular Communication | The pathogenesis of anemia was multifactorial, with decreased renal function (glomerular filtration rate <60 mL/min/1.73 m(2)), signs of inflammation, and functional iron deficiency detected in 11.4% of anemic patients. | 25092968 |
| Renal Insufficiency, Inflammation | Altered Intercellular Communication | A complex and heterogeneous interplay of chronic inflammation, functional iron deficiency, and renal impairment was identified in a large proportion of patients. | 25092968 |
| Inflammation, Anxiety, CTCAE 3.0, Depression, CTCAE, Sleep disturbances | Altered Intercellular Communication | Cross-sectional associations of complaints of sleep disturbances with cardiovascular risk factors and disease, biomarkers of inflammation, depression, anxiety, and physical health status were analyzed. | 25093413 |
| Inflammation, FAM126A gene | Altered Intercellular Communication | These data suggest that inflammation via the NFkB pathway play an important role in modulating gene expression of HCC patients through methylation. | 25093504 |
| Inflammation, Ulcer | Altered Intercellular Communication | Detected somewhat smaller difference in the degree of risk in the treatment of existing and improved schemes ulcer and neasotsiyovanoyi it when the underlying disease complicated by chronic inflammation, in our opinion, due to greater perfection, adapted first for this category of patients, among other options. | 25095689 |
| Vascular Diseases, Interstitial inflammation, Fibrosis Assessment, Tubulitis Assessment, Arteriolar Hyaline Thickening Assessment | Altered Intercellular Communication | The mean scores of interstitial inflammation (interstitial inflammation and tubulitis), scarring (interstitial fibrosis/tubular atrophy), and vascular disorders (arteriolar hyaline thickening and vascular intimal fibrosis) were significantly higher in late than early acute cellular rejection. | 25095709 |
| Inflammation, Atherosclerosis | Altered Intercellular Communication | Inflammation has a prominent role in the development of atherosclerosis. | 25095741 |
| Inflammation, Diabetes Mellitus, Non-Insulin-Dependent, Atherosclerosis | Altered Intercellular Communication | Type 2 diabetes could contribute to atherosclerosis development by promoting inflammation. | 25095741 |
| Intermittent Claudication, Peripheral Arterial Diseases, Musculoskeletal Physiological Phenomena | Altered Intercellular Communication | Inflammation contributes to the development of peripheral artery disease (PAD) and may contribute to intermittent claudication by adversely affecting vascular and skeletal muscle function. | 25095746 |
| Inflammation, Impaired health, Intermittent Claudication | Altered Intercellular Communication | Systemic inflammation, as indicated by TNF-a inflammatory gene expression in peripheral blood monocytes and by circulating biomarker levels, is associated with impairment in walking time in patients with PAD and intermittent claudication. | 25095746 |
| Inflammation, Thrombosis | Altered Intercellular Communication | Galectin-3, a biomarker linking oxidative stress and inflammation with the clinical outcomes of patients with atherothrombosis. | 25095870 |
| Inflammation, Thrombosis | Altered Intercellular Communication | Galectin-3 (Gal-3) participates in different mechanisms involved in atherothrombosis, such as inflammation, proliferation, or macrophage chemotaxis. | 25095870 |
| Rupture, Inflammation, Atherosclerosis | Altered Intercellular Communication | Gal-3 extracellular levels could reflect key underlying mechanisms involved in atherosclerosis etiology, development, and plaque rupture, such as inflammation, infiltration of circulating cells and oxidative stress. | 25095870 |
| ARCN1 gene, Specific antibody deficiency, Inflammation | Altered Intercellular Communication | We hypothesised that functional defects in Tregs may promote increased inflammation contributing to the pathogenesis of COPD. | 25097153 |
| ARCN1 gene, Inflammation, Obesity | Altered Intercellular Communication | Obesity and/or perturbed homeostasis of Treg subsets may explain this defect and therefore contribute to increased inflammation observed in COPD. | 25097153 |
| Inflammation, Keratitis | Altered Intercellular Communication | Acanthamoeba keratitis was defined as the presence of AK with concurrent ipsilateral scleral inflammation. | 25097155 |
| Inflammation, Pain Distress Question | Altered Intercellular Communication | Control of scleral inflammation and pain was achieved in all but 2 eyes (2 enucleations). | 25097155 |
| methyldopa, Inflammation, Hypertension, CTCAE, Communicable Diseases | Altered Intercellular Communication | The new evidence strongly suggests a relationship between AMD development and hypertension (p < 0.001; r = +0.30, P < 95%) as well as between AMD progression and hypertension accompanied by chronic inflammation with predominantly intracellular localization of the infectious agent (p < 0.05 for the predisciform stage, p < 0.001 for the disciform and cicatrical stages; r = +0.30, P < 95%). | 25098114 |
| methyldopa, Inflammation, Hypertension, CTCAE, Communicable Diseases | Altered Intercellular Communication | AMD progression is associated with hypertension accompanied by chronic inflammation with predominantly intracellular localization of the infectious agent as well as impairment of the interferon response (systemic decrease of IFNalpha and IFNgamma with local increase of IFNalpha). | 25098114 |
| Inflammation, Presenile dementia, Chronic osteomyelitis, cyclophosphamide/methotrexate/vincristine protocol, Disease | Altered Intercellular Communication | The role of chronic osteomyelitis (COM), a disorder characterized by persistent inflammation, in dementia development has not been fully explored. | 25098680 |
| Inflammation, Myositis, CTCAE 5.0 | Altered Intercellular Communication | Upregulation of immunoproteasome subunits in myositis indicates active inflammation with involvement of antigen presenting cells, CD8 T-cells and IFNG. | 25098831 |
| Inflammation, Metabolic Syndrome X | Altered Intercellular Communication | Metabolic syndrome criteria as predictors of insulin resistance, inflammation and mortality in chronic hemodialysis patients. | 25099153 |
| Inflammation, Metabolic Syndrome X | Altered Intercellular Communication | Diagnosis of metabolic syndrome by HMetS was simultaneously capable of revealing both inflammation and IR, whereas NCEP ATP III and IDF criteria were only able to identify IR. | 25099153 |
| Inflammation, Metabolic Syndrome X | Altered Intercellular Communication | IR and inflammation predict metabolic syndrome only when diagnosed by HMetS criteria. | 25099153 |
| Inflammation, Necrosis, Blood Clot, Bulla, Vasculitis, CTCAE | Altered Intercellular Communication | Premortem and autopsy skin biopsies demonstrated epidermal necrosis, subepidermal bullae, and fibrin thrombi within small cutaneous vessels with minimal perivascular lymphocytic inflammation and without accompanying vasculitis. | 25099358 |
| Gastrointestinal inflammation, Colitis | Altered Intercellular Communication | In CD colitis mice, intestinal inflammation via CD4(+) T cell hyperactivation was induced by food antigens associated with high serum IgG levels and was ameliorated by the elimination of food antigens. | 25099432 |
| Hyponatremia | Altered Intercellular Communication | Patients with new-onset severe hyponatremia and no obvious pharmacologic or systemic cause should undergo pituitary hormonal evaluation and brain imaging. | 25100360 |
| Tyrosine Transaminase Deficiency Disease, hyponatremic | Altered Intercellular Communication | Surgical resection and correction of hormonal deficiencies are associated with resolution of recurrent hyponatremic episodes. | 25100360 |
| Alzheimers Disease | Altered Intercellular Communication | Is Alzheimer's Disease Autoimmune Inflammation of the Brain That Can be Treated With Nasal Nonsteroidal Anti-Inflammatory Drugs? | 25100747 |
| Alzheimers Disease", Have Autoimmune or Inflammatory Condition, MS gene | Altered Intercellular Communication | Like Alzheimer's, multiple sclerosis, an autoimmune inflammation of the central nervous system, has a female to male ratio of 2.3. | 25100747 |
| Inflammation, Diverticulum | Altered Intercellular Communication | Laboratory parameters revealed inflammation signs, and instrumental examinations showed the presence of diverticula in the ascending colon. | 25100894 |
| Inflammation, Atherosclerosis | Altered Intercellular Communication | Chronic inflammation and immunosenescence result in early onset of conditions associated with aging, including atherosclerosis and frailty. | 25101530 |
| Inflammation | Altered Intercellular Communication | These changes correlate with inflammation and disease duration and suggest that disconnection of oligodendrocytes from reactive astrocytes may play a role in failed remyelination and disease progression. | 25101702 |
| Inflammation, Intracranial Aneurysm, Rupture | Altered Intercellular Communication | Chronic inflammation contributes to remodeling, degeneration, and rupture of saccular intracranial artery aneurysms. | 25101705 |
| Inflammation, Oral infection, Periodontitis, Endothelium | Altered Intercellular Communication | These findings further support the notion that oral infections have extraoral effects and document that periodontitis is associated with a mobilization of EPCs from the bone marrow, apparently in response to systemic inflammation and endothelial injury. | 25101916 |
| Inflammation, Obesity | Altered Intercellular Communication | In non-diabetic subjects, a mechanism has been proposed in which chronic inflammation associated with obesity increases albumin metabolism and negatively regulates GA levels. | 25102071 |
| Inflammation | Altered Intercellular Communication | BMI was significantly positively correlated with CRP, but CRP was not significantly correlated with GA. HOMA-b was significantly positively correlated with BMI and significantly negatively correlated with GA. Multivariate analysis showed that HOMA-b was a significant explanatory variable for GA, but not CRP and HOMA-R. Our findings suggest that insulin secretion plays a greater role than chronic inflammation in the mechanism by which BMI negatively regulates GA in T2DM patients. | 25102071 |
| Inflammation, Chronic disease | Altered Intercellular Communication | Inflammation is implicated in the development of chronic diseases and increases the risk of mortality. | 25102453 |
| Inflammation | Altered Intercellular Communication | Daily positive events may serve a protective role against inflammation. | 25102453 |
| Ulcerative Colitis, Colitis | Altered Intercellular Communication | Whole Fusobacterium species, but not F. nucleatum, are common in UC patients and have a role in persistence of colonic inflammation in UC. | 25102986 |
| Airway structure, ARCN1 gene | Altered Intercellular Communication | Association between pathogens detected using quantitative polymerase chain reaction with airway inflammation in COPD at stable state and exacerbations. | 25103335 |
| Airway structure, ARCN1 gene | Altered Intercellular Communication | Relationships between airway inflammation and respiratory potentially pathogenic microorganisms (PPMs) quantified using quantitative polymerase chain reaction (qPCR) in subjects with COPD are unclear. | 25103335 |
| Airway structure, ARCN1 gene | Altered Intercellular Communication | Our aim was to evaluate mediators of airway inflammation and their association with PPMs in subjects with COPD at stable state and during exacerbations. | 25103335 |
| Airway structure, ARCN1 gene | Altered Intercellular Communication | At stable state, H influenzae is associated with increased airway inflammation in COPD. | 25103335 |
| Airway structure | Altered Intercellular Communication | The relationship between bacterial load changes of specific pathogens and airway inflammation at exacerbation and recovery warrants further investigation. | 25103335 |
| TG gene, Inflammation | Altered Intercellular Communication | Patients with isolated TG were older (52 +- 14 vs. 35 +- 14; p = 0.0048), received grafts from older donors (54 +- 16 vs. 41 +- 18; p = 0.0554), and displayed a lower inflammation in the glomerular (g-score: 0.5 +- 0.5 vs. 1.0 +- 0.9; p = 0.0865; CD3 positive cells/glomeruli: 1.5 +- 2.9 vs. 4.4 +- 4.1; p = 0.0147), interstitial (i-score: 1.2 +- 0.9 vs. 1.9 +- 1.0; p = 0.0685; CD45 positive cells/hpf: 18 +- 11 vs. 57 +- 68; p = 0.0132), and peritubular capillary (ptc-score 0.2 +- 0.6 vs. 1.1 +- 0.9; p = 0.0089; CD45 positive cells/hpf: 3.7 +- 3.1 vs. 10.1 +- 7.4; p = 0.0290) compartments. | 25103874 |
| TG gene, Inflammation | Altered Intercellular Communication | Isolated TG is associated with less severe allograft inflammation and with a better outcome than chronic AMR. | 25103874 |
| Inflammation, Chronic sinusitis, Craniosynostosis | Altered Intercellular Communication | Chronic rhinosinusitis (CRS) defines a group of disorders characterized by persistent inflammation of the sinonasal tract. | 25104359 |
| Inflammation | Altered Intercellular Communication | Features of epithelial dedifferentiation towards a mesenchymal phenotype are observed in CRSwNP and CRSsNP and correlate with airway fibrosis and inflammation. | 25104359 |
| Myelitis, Tropical Spastic Paraparesis | Altered Intercellular Communication | Human T-lymphotropic virus type 1 (HTLV-1) can cause chronic spinal cord inflammation, known as HTLV-1-associated myelopathy/tropical spastic paraparesis (HAM/TSP). | 25104771 |
| TNF protein, human, Inflammation, Hypertension, CTCAE, Diabetes Mellitus | Altered Intercellular Communication | The present studies have demonstrated an independent association of higher PP with higher TNF-a, a marker of insulin resistance, and neutrophil count in community-living elderly women and suggest that insulin resistance and chronic low-grade inflammation may in part be responsible for the association between high PP and incident type 2 diabetes found in elderly patients with hypertension. | 25105150 |
| Acute heart failure | Altered Intercellular Communication | The systemic inflammation-based Glasgow Prognostic Score as a prognostic factor in patients with acute heart failure. | 25105282 |
| Inflammation | Altered Intercellular Communication | The GPS, which is based on systemic inflammation, is useful for predicting the prognoses of hospitalized patients with ADHF. | 25105282 |
| Inflammation | Altered Intercellular Communication | The objective of this study was to compare epidemiology, causative pathogens, outcome, and levels of laboratory markers of inflammation of community-onset (i.e. | 25105287 |
| Inflammation, Atherosclerosis | Altered Intercellular Communication | Inflammation is increasingly being recognized as an important factor in the pathogenesis of atherosclerosis and outcome of percutaneous coronary intervention (PCI). | 25105946 |
| Inflammatory Bowel Diseases | Altered Intercellular Communication | The impact of hormonal contraception on disease-related cyclical symptoms in women with inflammatory bowel diseases. | 25105949 |
| Barrett Esophagus, Inflammation, Adenocarcinoma Of Esophagus | Altered Intercellular Communication | Inflammation and oxidative stress markers and esophageal adenocarcinoma incidence in a Barrett's esophagus cohort. | 25106775 |
| Inflammation, Adenocarcinoma Of Esophagus, Malignant Neoplasms | Altered Intercellular Communication | Prediagnostic inflammation markers predict several cancers, but their role in predicting esophageal adenocarcinoma is unknown. | 25106775 |
| Barrett Esophagus, Inflammation, Adenocarcinoma Of Esophagus | Altered Intercellular Communication | Further research is needed to evaluate the role of inflammation and associated markers in esophageal adenocarcinoma development in persons with Barrett's esophagus. | 25106775 |
| Inflammation, Adenocarcinoma Of Esophagus | Altered Intercellular Communication | This prospective study suggests that inflammation markers, particularly CRP and IL6, may help identify persons at higher risk of progression to esophageal adenocarcinoma. | 25106775 |
| Cardiovascular morbidity, Hypopituitarism | Altered Intercellular Communication | Chronic hypopituitarism, particularly growth hormone (GH) deficiency is related to the increased cardiovascular morbidity and mortality. | 25107344 |
| Inflammation | Altered Intercellular Communication | This difference may ensource from deterioration of the balance of these substances due to oxidative stress and inflammation. | 25107374 |
| Inflammation, Rheumatoid Arthritis | Altered Intercellular Communication | Association between serum uric acid and inflammation in rheumatoid arthritis: perspective on lowering serum uric acid of leflunomide. | 25108207 |
| Refractory anemias, Inflammation, Rheumatoid Arthritis | Altered Intercellular Communication | The association between serum uric acid concentrations and inflammation in patients with rheumatoid arthritis (RA) has been still controversial. | 25108207 |
| Refractory anemias, Inflammation | Altered Intercellular Communication | This implies that uric acid may not influence systemic inflammation in RA. | 25108207 |
| Inflammation, Nephritis | Altered Intercellular Communication | We then divided this population again into group 3 (n = 20) with <= 25% inflammation and group 4 (n = 18) with >26% inflammation based on the Banff score for renal parenchyma inflammation. | 25109692 |
| Inflammation, Fibrosis Assessment | Altered Intercellular Communication | The accuracy of ZC in determining moderate cortical fibrosis and moderate inflammation was examined by receiver operating characteristic analysis. | 25109692 |
| Inflammation, Fibrosis Assessment | Altered Intercellular Communication | The area under the receiver operating characteristic curve was 0.992 +- 0.010 for fibrosis and 0.988 +- 0.021 for inflammation. | 25109692 |
| Inflammation, Fibrosis Assessment | Altered Intercellular Communication | ZC is a new strain marker that could be straightforward to interpret and perform, making it a potentially practical approach for monitoring progression of cortical fibrosis or inflammation in renal allografts. | 25109692 |
| Crohn Disease | Altered Intercellular Communication | Crohn's disease (CD) is a lifelong, relapsing and remitting inflammatory condition of the intestine. | 25110044 |
| Inflammation, Diverticulitis | Altered Intercellular Communication | Furthermore, left-sided disease was significantly associated with a higher incidence of complicated diverticulitis (89.2% vs 57.5%, P < 0.01), combined resection due to extensive inflammation (21.6% vs 5.0%, P < 0.05), operative complications (51.4% vs 27.5%, P < 0.05), and in-hospital mortality (10.8% vs 0%, P < 0.05), along with longer post-operative hospitalization duration (21.3 +- 10.2 d vs 10.6 +- 8.1 d, P < 0.05). | 25110438 |
| Inflammation | Altered Intercellular Communication | Modeling the association between lifecourse socioeconomic disadvantage and systemic inflammation in healthy adults: The role of self-control. | 25110854 |
| Inflammation | Altered Intercellular Communication | Results showed that lower self-control primarily operated through higher abdominal adiposity to associate with greater inflammation. | 25110854 |
| Inflammation, Diabetes Mellitus | Altered Intercellular Communication | Gender, diabetes, glomerular filtration rate (GFR), hemoglobin, PTH, markers of mineral metabolism, inflammation, iron status and nutrition were variables of adjustment in univariate and multivariate analysis. | 25113067 |
| Hyperparathyroidism, Anemia | Altered Intercellular Communication | Parathyroid hormone (PTH) has been associated with anemia only in dialysis patients with severe hyperparathyroidism. | 25113067 |
| Leishmaniasis, Visceral, Renal tubular disorder, Nephritis | Altered Intercellular Communication | Preliminary study on tubuloglomerular dysfunction and evidence of renal inflammation in patients with visceral leishmaniasis. | 25114011 |
| Nephritis | Altered Intercellular Communication | Urinary MCP-1 and MDA are elevated in patients with VL, which suggests renal inflammation and incipient renal damage. | 25114011 |
| ARCN1 gene, Inflammation, Chronic Obstructive Airway Disease | Altered Intercellular Communication | The role of interleukins in the severity and clinical profile of chronic obstructive pulmonary disease (COPD) is not known, but evidence supports the contribution of systemic inflammation to disease pathophysiology. | 25114519 |
| Fitz-Hugh-Curtis syndrome, Inflammation, Pelvic Inflammatory Disease | Altered Intercellular Communication | Fitz-Hugh-Curtis syndrome (FHCS) is caused by inflammation of perihepatic capsules associated with pelvic inflammatory disease. | 25115526 |
| Inflammation | Altered Intercellular Communication | NTM infection can cause various clinical manifestations, which in the present case, overlapped with the symptoms of perihepatic inflammation seen in FHCS. | 25115526 |
| Inflammation, Bothered by Vomiting, Diarrhea, Asthenia, Fatigue | Altered Intercellular Communication | A total of 85.8 % of all patients experienced at least one AE: fatigue (56.7 %), vomiting (40.1 %), diarrhea (33.7 %), asthenia (32.8 %), and mucosal inflammation (20.8 %). | 25115744 |
| Inflammation | Altered Intercellular Communication | On multivariate logistic regression analysis, oxidative stress index (b = 0.868, 95% confidence interval [CI] = 0.806-0.934, P < .001), neutrophil to lymphocyte ratio, uric acid, mean platelet volume, Killip 2 to 4 class, and initial SYNTAX score were independently associated with SR. Oxidative stress as well as inflammation may play a pivotal role in the pathogenesis of SR in patients with STEMI. | 25115763 |
| Inflammation, Atherosclerotic lesion | Altered Intercellular Communication | Growth differentiation factor 15 (GDF-15), a member of the transforming growth factor superfamily, is produced by cardiomyocytes and atherosclerotic lesions under stress conditions such as inflammation. | 25117302 |
| Malnutrition, HD Term Type, Inflammation, Atherosclerosis | Altered Intercellular Communication | The relationship between serum GDF-15, mortality, and carotid artery thickening suggests that GDF-15 may be a novel marker of atherosclerosis, inflammation, and malnutrition in HD patients. | 25117302 |
| Inflammation, Fibrosis Assessment, Calcified (qualifier) | Altered Intercellular Communication | Histologically, they contained variable amounts of hyaline ribbons and rings, inflammation, foreign body giant cells, calcifications, and food; larger lesions displayed circumferential stellate fibrosis (12/22). | 25118813 |
| Cataract, Inflammation | Altered Intercellular Communication | Surgical inflammation associated with cataract surgery caused a significant increase of macular thickness in control and DR eyes that were not treated with intravitreous bevacizumab. | 25118827 |
| Inflammation, Organ Dysfunction Scores | Altered Intercellular Communication | Cardiac surgery is accompanied by an increase of oxidative stress, a significantly reduced antioxidant (AOX) capacity, postoperative inflammation, all of which may promote the development of organ dysfunction and an increase in mortality. | 25118980 |
| Inflammation, Hematuria, CTCAE | Altered Intercellular Communication | Laboratory tests revealed evidence of an inflammation and a hematuria. | 25119306 |
| Neurodegenerative Disorders, Inflammation, Nerve Degeneration, Mitochondria, Neuronal loss in central nervous system | Altered Intercellular Communication | Despite exhibiting different clinical profiles and selective neuronal loss, common features such as abnormal protein deposition, dysfunctional cellular transport, mitochondrial deficits, glutamate excitotoxicity, iron accumulation and inflammation are observed in many neurodegenerative disorders, suggesting converging pathways of neurodegeneration. | 25119539 |
| Multiple Organ Failure, Inflammation, Lung Injury, Hypoxemia | Altered Intercellular Communication | It causes inflammation of the lung parenchyma leading to impaired gas exchange with a systemic release of inflammatory mediators, causing consequential lung tissue injury, hypoxemia and frequently multiple organ failure. | 25120850 |
| Inflammation, Plaque, Atherosclerotic | Altered Intercellular Communication | A therapeutic regimen reducing FABP4 expression within the atherosclerotic plaque may promote lesion stability through modulation of endoplasmic reticulum stress signaling, and attenuation of apoptosis, lipid burden, and inflammation. | 25122052 |
| Inflammation | Altered Intercellular Communication | Nevertheless, in some reports, electrode extrusion, chronic inflammation, and even soft failure of the implant system have been attributed to a tissue response to the electrode. | 25122600 |
| Inflammation, Impaired cognition | Altered Intercellular Communication | Long-term systemic inflammation and cognitive impairment in a population-based cohort. | 25123210 |
| Inflammation, Impaired cognition | Altered Intercellular Communication | Evidence suggests inflammation is associated with cognitive impairment, but previous epidemiological studies have reported conflicting results. | 25123210 |
| Inflammation, Impaired cognition | Altered Intercellular Communication | Further studies of long-term inflammation and cognitive impairment are needed. | 25123210 |
| Inflammation, Asthma | Altered Intercellular Communication | The small airways are an important site of inflammation in asthma. | 25123492 |
| Refractory anemias, Inflammation | Altered Intercellular Communication | We studied the usefulness of magnetic resonance imaging (MRI) in detecting subclinical inflammation in patients with asymptomatic RA and tested the hypothesis of interleukin (IL)-18 as a marker of disease activity. | 25123522 |
| Refractory anemias, Superficial ulcer, Inflammation | Altered Intercellular Communication | MRI is more sensitive in detecting erosions compared with X-rays, and is superior in its ability to detect subclinical inflammation in RA patients. | 25123522 |
| Inflammation, Bodily secretions | Altered Intercellular Communication | Induced sputum allows to measure mediators of asthmatic inflammation in bronchial secretions. | 25123806 |
| Intraocular inflammation, Humor, Atrophic iris | Altered Intercellular Communication | Among the three groups of patients, the characteristic features of those with VZV-AU were severe intraocular inflammation, as shown by severe aqueous flare, highest viral load in the aqueous humor, and presence of segmental iris atrophy. | 25124341 |
| Intraocular inflammation | Altered Intercellular Communication | In comparison, patients with CMV-AU had the mildest intraocular inflammation, lowest corneal endothelial cell density, and highest IOP. | 25124341 |
| Delirium, Inflammation | Altered Intercellular Communication | This study provides novel evidence of CNS inflammation involving the IL-1b family in delirium and suggests a rise in CSF IL-1b early in delirium pathogenesis. | 25124807 |
| Delirium, Inflammation | Altered Intercellular Communication | Future larger CSF studies should examine the role of CNS inflammation in delirium and its sequelae. | 25124807 |
| Inflammation, Endothelial dysfunction, Coronary Lesions Treated | Altered Intercellular Communication | Ongoing low-grade inflammation and endothelial dysfunction persist in children with coronary lesions diagnosed with Kawasaki disease (KD). | 25124974 |
| Coronary Aneurysm, Inflammation | Altered Intercellular Communication | Pravastatin improves endothelial function and reduces low-grade chronic inflammation in patients with coronary aneurysms due to KD. | 25124974 |
| Inflammatory abnormality of the eye | Altered Intercellular Communication | In this observational small case series, data were collected successively from May 1, 2012, through February 31, 2013, from patients with clinical signs of ocular inflammation treated with vemurafenib at the Department of Ophthalmology, Cochin-Hotel-Dieu Hospital. | 25125216 |
| Inflammation, Panuveitis, Retinal Detachment, Uveitis, Manufactured sign | Altered Intercellular Communication | The mean (SD) time until the appearance of ocular signs was 5.6 (2.3) months (range, 19 days to 7 months), and inflammation ranged from mild or low-grade anterior uveitis to severe explosive panuveitis complicated by retinal detachment. | 25125216 |
| Inflammation, Primary malignant neoplasm, Chronic Obstructive Airway Disease, Chronic disease, Muscle (organ) | Altered Intercellular Communication | This is important because a number of age-related clinical circumstances trigger acute and chronic muscle loss including cancer, chronic obstructive pulmonary disease, hospitalization, acute and chronic illness, and diseases in which systemic inflammation occurs. | 25125716 |
| Airway structure, Inflammation | Altered Intercellular Communication | It results from chronic inflammation and causes irreversible airway damage. | 25125975 |
| ARCN1 gene, Inflammation | Altered Intercellular Communication | Levels of different serum cytokines could be surrogate biomarkers for inflammation and lung function in COPD. | 25125975 |
| Inflammation, Periodontitis, Demographics Domain | Altered Intercellular Communication | Periodontitis in these patients is characterized by severe inflammation and tissue breakdown, and its diagnosis is important for cures of periodontitis and DM. | 25126693 |
| Inflammation, "Alzheimers Disease", Data types - Address | Altered Intercellular Communication | Accumulation of b-amyloid (Ab) and resultant inflammation are critical pathological features of Alzheimer disease (AD). | 25126727 |
| Burn Specimen Source Codes | Altered Intercellular Communication | Ascorbic acid (vitamin C) decreases systemic inflammation and lowers fluid requirements after thermal injury; therefore it has been adopted in many burn centers as an adjunct to resuscitation. | 25127026 |
| Inflammation, Ulcerative Colitis | Altered Intercellular Communication | Potential utility of a new ulcerative colitis segmental endoscopic index combining disease severity and the extent of inflammation. | 25127112 |
| Inflammation, Ulcerative Colitis | Altered Intercellular Communication | To investigate the potential utility of a new scoring system, the Ulcerative Colitis Segmental Endoscopic Index (UCSEI), which combines measures of disease severity and extent of inflammation. | 25127112 |
| Inflammation, Ulcerative Colitis | Altered Intercellular Communication | UCSEI, reflecting disease severity and extent of inflammation, provides useful information for UC management that is not available with MES. | 25127112 |
| Intraocular inflammation, Unspecified visual loss | Altered Intercellular Communication | In the perioperative period following the second of the two surgeries, both patients developed severe, bilateral intraocular inflammation and profound vision loss. | 25127533 |
| Appendicitis, CTCAE | Altered Intercellular Communication | The proposed CT criterion of the DWC is not affected by normal distension or periappendiceal inflammation but only by true appendicitis. | 25127845 |
| Inflammation, Depression, CTCAE, Diabetes Mellitus | Altered Intercellular Communication | Further investigation into this relationship could aid in understanding the mechanisms underlying inflammation, depression, and diabetes. | 25128285 |
| Hepatitis A, Inflammation, Fibrosis Assessment | Altered Intercellular Communication | Liver biopsy samples were classified into five levels of inflammation (G) and fibrosis (S) stages, according to the Chinese guidelines for prevention and treatment of viral hepatitis. | 25128299 |
| Inflammation, Fibrosis Assessment | Altered Intercellular Communication | Two multivariable ordinal regression models were performed to determine associations between AFP, GGT, and APRI (AST/PLT ratio) and stages of inflammation and fibrosis. | 25128299 |
| Inflammation, Fibrosis Assessment | Altered Intercellular Communication | Significant positive and moderate correlations were shown between AFP levels and inflammation stages and between AFP levels and fibrosis stages (r = 0.436 and 0.404, p < 0.001). | 25128299 |
| Inflammation, Fibrosis Assessment | Altered Intercellular Communication | Receiver operating characteristic (ROC) curve analyses revealed that the areas under the curves (AUCs) were 0.685, 0.727, and 0.755 (all p <0.001) for judging inflammation stages of G >= 2, G >= 3, G = 4 by AFP; and 0.691, 0.717, and 0.718 (all p <0.001) for judging fibrosis stages of S >= 2, S >= 3, and S = 4 by AFP. | 25128299 |
| Inflammation, Fibrosis Assessment, Complete atrioventricular block | Altered Intercellular Communication | Serum AFP levels increased as pathological levels of inflammation and fibrosis increased in CHB patients. | 25128299 |
| Fibrosis Assessment, Hepatitis | Altered Intercellular Communication | Our data showed the clinical significance of serum AFP levels in diagnosing liver inflammation and fibrosis. | 25128299 |
| Inflammation, Paresis, Paralysed | Altered Intercellular Communication | This leads to nerve inflammation and damage that can cause muscle weakness and/or paralysis, including foot drop. | 25128306 |
| Inflammation, Autoimmune Diseases, Exocrine Glands, "Sjogrens Syndrome", PEELING SKIN SYNDROME | Altered Intercellular Communication | Characterized by chronic inflammation, dysfunction of exocrine glands, and systemic autoimmunity, primary Sjogren syndrome (pSS) is a common autoimmune disease in elderly women. | 25128511 |
| Sepsis, Communicable Diseases, Inflammation | Altered Intercellular Communication | Differentiating sepsis from other noninfectious causes of systemic inflammation is often difficult in the elderly. | 25130150 |
| Inflammation, Acute depression, Bipolar Disorder | Altered Intercellular Communication | Persistent inflammation and its relationship to leptin and insulin in phases of bipolar disorder from acute depression to full remission. | 25130211 |
| Inflammation, Bipolar Disorder | Altered Intercellular Communication | Patients with bipolar disorder in depressive episodes may exhibit persistent inflammation with elevated levels of hs-CRP, IL-1Ra, sTNF-R1, and sIL-2R but not sIL-6R from the acute phases to full remission. | 25130211 |
| Inflammation, Glaucoma, CTCAE | Altered Intercellular Communication | Rejection episodes and graft failure were recorded, together with preoperative risk factors (glaucoma, neovascularization and active inflammation). | 25130326 |
| Inflammation, Overweight, Cardiovascular Diseases | Altered Intercellular Communication | Research investigating dietary influences on inflammation has focused primarily on the relationship between dietary characteristics, CRP elevation and BMI in the populations at greatest risk for cardiovascular disease, namely those in the overweight and obese ranges, often in clinical settings and/or among those middle aged or older, leaving little information about normal to underweight populations of reproductive age in ecological settings. | 25130535 |
| Xanthogranulomatous inflammation, Blood Clot, Necrosis | Altered Intercellular Communication | Histology of the resected unhealthy graft showed an arterial thrombus with xanthogranulomatous inflammation and necrosis. | 25131097 |
| Inflammation, Metabolic Syndrome X, ETV3 wt Allele, Endothelial dysfunction, Hypertension, CTCAE | Altered Intercellular Communication | High serum uric acid (SUA) levels are present in patients with metabolic syndrome (MetS), when the latter is associated with endothelial dysfunction, inflammation, and hypertension. | 25131560 |
| Inflammation | Altered Intercellular Communication | In order to avoid further displacement due to the inflammation, 61 was extracted at the first appointment. | 25131644 |
| Inflammation, Electrocardiogram: myocardial infarction (finding), Rupture | Altered Intercellular Communication | Acute myocardial infarction (AMI), is related to a diffuse active inflammation of the coronary tree associated with rupture of one of the multiple vulnerable plaques. | 25131923 |
| Inflammation, Dental Plaque | Altered Intercellular Communication | The presence of soluble mediators of inflammation with their synergic or antagonistic actions coordinates the physiological response determining the plaque fate and the fatal event. | 25131923 |
| Acute myocardial infarction, Inflammation | Altered Intercellular Communication | The presence of CX3CR1 polymorphisms is significantly correlated with the incidence and the outcome of acute myocardial infarction inducing in the whole coronary tree a strong recruitment of Th1 polarized inflammation that is directly correlated to PTX3 expression. | 25131923 |
| Degenerative polyarthritis, Inflammation | Altered Intercellular Communication | YKL-40 as a novel factor associated with inflammation and catabolic mechanisms in osteoarthritic joints. | 25132728 |
| Inflammation, Asthma, Rheumatoid Arthritis, Tissue injury | Altered Intercellular Communication | YKL-40 is associated with tissue injury and inflammation, and consequently to diseases in which these mechanisms lead to tissue degradation, for example, asthma and rheumatoid arthritis. | 25132728 |
| Cartilage destruction, Inflammation, Degenerative polyarthritis | Altered Intercellular Communication | The present study introduces YKL-40 as a cartilage-derived factor associated with mediators of inflammation and cartilage destruction involved in the pathogenesis of OA. | 25132728 |
| Inflammation, Fibrosis Assessment | Altered Intercellular Communication | CAP was not correlated with inflammation degree and fibrosis degree (r = -0.025, P > 0.05; r = 0. | 25132779 |
| Inflammatory Bowel Diseases, Inflammation | Altered Intercellular Communication | Relationship between methylation and colonic inflammation in inflammatory bowel disease. | 25132780 |
| Inflammatory Bowel Diseases, Colitis | Altered Intercellular Communication | To investigate the relationship between the methylation status in the SLIT2 and TGFB2 promoters and colonic inflammation in inflammatory bowel disease patients. | 25132780 |
| Inflammation | Altered Intercellular Communication | SLIT2 methylation was also higher in samples with acute inflammation (56.5%) than in samples with chronic (24%) or absent inflammation (15%) (P < 0.001). | 25132780 |
| Inflammation | Altered Intercellular Communication | In the multivariate analysis, only inflammation status (and not disease duration or extension) was independently associated with SLIT2 methylation [OR = 6.6 (95%CI: 1.65-27.36), P = 0.009]. | 25132780 |
| Inflammation | Altered Intercellular Communication | Endoscopic and histological inflammation are predictive for SLIT2 methylation. | 25132780 |
| Inflammation, Malignant Neoplasms | Altered Intercellular Communication | We are often confronted with patients in the "gray zone" (prostate-specific antigen [PSA]<10 ng/mL) whose biopsies reveal no malignancy but only inflammation. | 25132947 |
| Inflammation, Prostate carcinoma | Altered Intercellular Communication | We investigated the relationship between histological inflammation and total PSA (tPSA), free PSA (fPSA), and percentage of free PSA (f/tPSA) levels in patients without prostate cancer (PC). | 25132947 |
| Inflammation, prostatitis | Altered Intercellular Communication | Subclinical inflammation has a significant influence on fPSA in patients with tPSA<10 ng/mL but without PC or clinical prostatitis. | 25132947 |
| Inflammation | Altered Intercellular Communication | Subclinical inflammation is not characterized by elevated tPSA alone but also by a decreased fPSA, a tendency similar to that in PC. | 25132947 |
| Coinfection, Inflammation | Altered Intercellular Communication | Coinfection with human herpesvirus 8 is associated with persistent inflammation and immune activation in virologically suppressed HIV-infected patients. | 25133669 |
| Communicable Diseases, Inflammation | Altered Intercellular Communication | Infection with co-pathogens is one of the postulated factors contributing to persistent inflammation and non-AIDS events in virologically-suppressed HIV-infected patients. | 25133669 |
| Coinfection, Inflammation, human herpesvirus 8 | Altered Intercellular Communication | In virologically suppressed HIV-infected patients, coinfection with HHV-8 is associated with increased inflammation and immune activation. | 25133669 |
| Anxiety, CTCAE 3.0, Inflammation, Depression, CTCAE | Altered Intercellular Communication | Patients experiencing depression or anxiety and those with elevated inflammation may be at particular risk for poor sleep. | 25133898 |
| Communicable Diseases, Noncommunicable Diseases, Inflammation | Altered Intercellular Communication | Serum procalcitonin is commonly used to differentiate systemic inflammation due to infection from non-infectious causes. | 25134378 |
| Acute inflammation | Altered Intercellular Communication | Patients at low risk for postoperative inflammation were recruited and randomized to the nepafenac group or to the control group. | 25135542 |
| Inflammation, Fibrosis Assessment | Altered Intercellular Communication | Histopathology of the grafts of eyes that required repeat DSAEK showed no inflammation, no foreign-body deposit, and no fibrosis. | 25135544 |
| Autosomal Recessive Disorder, Inflammation | Altered Intercellular Communication | Leukocyte adhesion deficiency type 1 (LAD-1) is an autosomal recessive disorder, caused by the absence or reduced expression of the beta-2 integrins on granulocytes, and characterized by the inability of these cells to emigrate from the bloodstream towards the sites of tissue inflammation. | 25135596 |
| ARCN1 gene, Inflammation, Depression, CTCAE | Altered Intercellular Communication | Persistent systemic inflammation and symptoms of depression among patients with COPD in the ECLIPSE cohort. | 25135745 |
| ARCN1 gene, Inflammation, Depression, CTCAE | Altered Intercellular Communication | The relationship of depression with systemic inflammation in COPD remains unknown. | 25135745 |
| Primary malignant neoplasm, Gastrointestinal inflammation | Altered Intercellular Communication | Faecal calprotectin (FC) is a surrogate marker for intestinal inflammation but not cancer. | 25135754 |
| Inflammation, CNS disorder | Altered Intercellular Communication | Conversely, in other CNS disorders signals from stressed cells may help control inflammation and inhibit degeneration. | 25135977 |
| Inflammation, liposarcoma, Lipoma, Hyperplasia | Altered Intercellular Communication | It was found that Eag1 was aberrantly expressed in over 67% liposarcomas, with a higher frequency than in lipoma, hyperplasia, inflammation, and normal adipose tissues. | 25136578 |
| Inflammation, Epithelial, Corneal Opacity, Corneal Neovascularization | Altered Intercellular Communication | We analyzed the best corrected visual acuity, epithelial defects, inflammation, corneal opacity, and corneal neovascularization. | 25136628 |
| Inflammation, Colorectal Carcinoma | Altered Intercellular Communication | Elevated endostatin levels in CRC correlate with systemic inflammation and invasion through the muscularis propria. | 25137019 |
| Inflammation | Altered Intercellular Communication | Thus, iron detection with MRI might provide a biomarker for chronic inflammation within lesions. | 25137340 |
| Esophageal Stricture, Inflammation | Altered Intercellular Communication | Repeated blister formation and ulceration, coupled with chronic inflammation, result in scarring and development of esophageal strictures. | 25138121 |
| Inflammation, Pathology | Altered Intercellular Communication | In the non-industrialized countries of Africa and Asia obstetric fistulas are more frequently caused by prolonged labour, whereas in countries with developed healthcare systems they are generally the result of complications of gynaecological surgery or, rarely, benign pathologies like inflammation or foreign bodies. | 25138359 |
| Communicable Diseases, Inflammation, Anemia | Altered Intercellular Communication | Further research is needed on the effect of chronic inflammation and infectious disease on anaemia in elderly women in rural China. | 25138800 |
| Inflammation, Malignant Neoplasms | Altered Intercellular Communication | The main indications for PET/CT were: characterization of an indeterminate mass on radiological imaging, suspicion or staging of malignancy, and suspicion of inflammation. | 25139518 |
| Inflammation, Cerebrovascular accident | Altered Intercellular Communication | Vital exhaustion, but not inflammation, partly mediated the association between a small social network and incident stroke. | 25139878 |
| Inflammation, Diabetes Mellitus, Non-alcoholic Fatty Liver Disease, Napping, Fatty Liver Disease | Altered Intercellular Communication | Both longer habitual day napping and Non-Alcoholic Fatty Liver Disease (NAFLD) are associated with diabetes and inflammation, but the association between day napping and NAFLD remains unexplored. | 25140521 |
| Vasculitis, Fibrosis Assessment | Altered Intercellular Communication | The histopathological findings comprise bizarre basophilic multinucleated cells (MC), small vessel inflammation, mild dermal fibrosis, and a sparse lymphohistiocytic infiltrate. | 25140659 |
| Inflammation, Hemorrhage, Drug Implant, Dental Plaque, Osteopenia | Altered Intercellular Communication | Gender, age, plaque index, gingival inflammation, keratinized mucosa, probing depth, bleeding, and implant loss data were recorded, and periapical radiographs were obtained for measurement of marginal bone loss. | 25141015 |
| Gingivitis, Dental Plaque, Osteopenia | Altered Intercellular Communication | Correlations were found between bone loss and plaque index and between bone loss and gender, but bone loss did not correlate with gingival inflammation, keratinized mucosa, probing depth, or age. | 25141015 |
| Pancreatitis | Altered Intercellular Communication | Consistently high serum ghrelin values during pancreatic inflammation suggest that ghrelin may be used as an adjunctive parameter in the monitoring of the course of the disease. | 25141321 |
| Inflammation | Altered Intercellular Communication | The positive stains were often located in deep pyloric glands and associated with chronic inflammation patterns (p = 0.045). | 25141489 |
| Barrett Esophagus, Inflammation | Altered Intercellular Communication | A more advanced form of inflammation and Barrett's esophagus was found only in patients over 45 years of age. | 25141579 |
| Inflammation | Altered Intercellular Communication | The presence of H. pylori infection was varied in the different types of inflammation. | 25141579 |
| Inflammation, Infection caused by Helicobacter pylori | Altered Intercellular Communication | In all patients, in whom biopsy specimens were taken from normal duodenal mucosa (14% of patients), histopathological examination revealed the presence of non-specific inflammation, regardless of the coexistence of H. pylori infection. | 25141579 |
| Inflammation, Abnormal degeneration | Altered Intercellular Communication | We examined serum for 20 biomarkers of inflammation, tissue degeneration, and repair. | 25141594 |
| Inflammation, Disorder of tendon | Altered Intercellular Communication | These results suggest that early onset tendinopathy with concurrent inflammation may be occurring in prolific texters. | 25141594 |
| Inflammation, Diabetes Mellitus, Cardiovascular Diseases | Altered Intercellular Communication | Inflammation and vagally mediated heart rate variability (vmHRV) have been implicated in a number of conditions including diabetes and cardiovascular disease. | 25141771 |
| Inflammation, Disease | Altered Intercellular Communication | Interventions targeted at vmHRV might be useful in the prevention of diseases associated with elevated systemic inflammation. | 25141771 |
| Intestinal metaplasia, Inflammation, Atrophic | Altered Intercellular Communication | Antrum samples presented higher degrees of atrophy, intestinal metaplasia, chronic inflammation and neutrophil activity. | 25142169 |
| Intestinal metaplasia, Inflammation | Altered Intercellular Communication | CagA genotype was significantly associated with higher degrees of intestinal metaplasia, neutrophil activity, chronic inflammation and OLGIM stages. | 25142169 |
| Refractory anemias, Inflammation | Altered Intercellular Communication | It indicates that CyPA may be involved in the regulation of the onset and development of inflammation process of RA. | 25142855 |
| Communicable Diseases, Inflammation | Altered Intercellular Communication | The presence of active inflammation or infection as suggested by an elevated ESR may negatively impact mobilization. | 25143186 |
| Gastrointestinal inflammation | Altered Intercellular Communication | Iron fortification adversely affects the gut microbiome, increases pathogen abundance and induces intestinal inflammation in Kenyan infants. | 25143342 |
| Diarrhea, Gastrointestinal inflammation | Altered Intercellular Communication | Secondary outcomes included faecal calprotectin (marker of intestinal inflammation) and incidence of diarrhoea. | 25143342 |
| Gastrointestinal inflammation | Altered Intercellular Communication | In this setting, provision of iron-containing MNPs to weaning infants adversely affects the gut microbiome, increasing pathogen abundance and causing intestinal inflammation. | 25143342 |
| Non-alcoholic Fatty Liver Disease, Inflammation, Malnutrition, Atherosclerosis | Altered Intercellular Communication | Nonalcoholic fatty liver disease (NAFLD) - a new factor that interplays between inflammation, malnutrition, and atherosclerosis in elderly hemodialysis patients. | 25143715 |
| Malnutrition, Obesity | Altered Intercellular Communication | In contrast to the general population for whom overnutrition or obesity is associated with increased cardiovascular risk, for patients who are maintained on hemodialysis (HD), malnutrition and malnutrition-inflammation complex syndrome are associated with poor outcome. | 25143715 |
| Inflammation, Malnutrition, Atherosclerosis, HD Term Type, Non-alcoholic Fatty Liver Disease | Altered Intercellular Communication | Our results indicated that NAFLD probably interplays between inflammation, malnutrition, and atherosclerosis in elderly HD patients. | 25143715 |
| Inflammation, Lymphoma | Altered Intercellular Communication | Despite its success in diagnosing and staging lymphoma, F-FDG PET/CT can be falsely positive in areas of posttreatment inflammation. | 25144214 |
| Inflammatory Bowel Diseases, Crohn Disease, Gastrointestinal inflammation, Ulcerative Colitis | Altered Intercellular Communication | Inflammatory bowel disease (IBD), encompassing ulcerative colitis (UC) and Crohn's disease (CD), is an uncontrolled chronic inflammation of the gastrointestinal tract caused by an interaction of diverse genes and environmental factors. | 25145003 |
| Inflammation | Altered Intercellular Communication | Histologically, the lesion showed chronic inflammation with a deposition of fiber-like foreign bodies. | 25145411 |
| Inflammation | Altered Intercellular Communication | The origin of these fiber-like foreign bodies remains unclear but might be related to chronic inflammation resulting from intratracheal intubations. | 25145411 |
| Inflammation, Endothelial dysfunction, Chronic Kidney Diseases | Altered Intercellular Communication | In CKD, uremic solutes may induce endothelial dysfunction, inflammation, and oxidative stress, leading to increased cardiovascular risk. | 25145928 |
| Suppuration, Granulomatous inflammation | Altered Intercellular Communication | Histology showed florid, suppurative, granulomatous inflammation in the dermis, with central microabscess formation surrounded by epithelioid histiocytes, scattered giant cells, and a small number of lymphocytes. | 25147085 |
| ARCN1 gene, airway disease, Airway structure, Chronic Obstructive Airway Disease, Bronchitis | Altered Intercellular Communication | Chronic Obstructive Pulmonary Disease (COPD) is a progressive airway disease characterised by neutrophilic airway inflammation or bronchitis. | 25148049 |
| Granuloma, Sarcoidosis, Inflammation | Altered Intercellular Communication | Granulomas consisting of macrophages with multinucleated giant cells and sparse lymphocytic inflammation are confined to the subcutaneous tissue, rather than to their usual location within the dermis in typical lesions of cutaneous sarcoidosis. | 25148276 |
| Inflammation | Altered Intercellular Communication | The data suggest that intrathecal administration of novel therapeutic agents targeting immune cells outside of the proliferation cycle may be necessary to effectively eliminate intrathecal inflammation in progressive MS. | 25148387 |
| Refractory anemias, BARRIER | Altered Intercellular Communication | In vitro modeling of reactive astrocytes resulted in increased expression of RALDH2, enhanced RA synthesis, and a protective role for astrocyte-derived RA on BBB function during inflammation-induced barrier loss. | 25149081 |
| Refractory anemias | Altered Intercellular Communication | Furthermore, RA induces endothelial immune quiescence and decreases monocyte adhesion under inflammatory conditions. | 25149081 |
| Inflammation, Diabetes Mellitus, Non-Insulin-Dependent | Altered Intercellular Communication | Human amylin oligomerizes quickly when oversecreted, which is toxic, induces inflammation in pancreatic islets and contributes to the development of T2D. | 25149184 |
| Communicable Diseases, Inflammation, Ischemic stroke, Neoplasms | Altered Intercellular Communication | The following causes were evaluated and ruled out: tumor, infection, ischemic stroke, non-infectious inflammation. | 25149958 |
| Colitis | Altered Intercellular Communication | P-317 (0.1mg/kg, ip and 1mg/kg, po) alleviated colonic inflammation in TNBS- and DSS-treated mice in the opioid receptor-dependent manner. | 25149976 |
| Depressive disorder, Depression, CTCAE | Altered Intercellular Communication | Clinical characteristics of inflammation-associated depression: Monocyte gene expression is age-related in major depressive disorder. | 25150007 |
| Eosinophilic inflammation | Altered Intercellular Communication | The FeNO levels in healthy school-aged children may reflect airway eosinophilic inflammation levels, and was affected by eosinophil count and age significantly. | 25150075 |
| Inflammation | Altered Intercellular Communication | RHEUMDOC: a one-page RHEUMatology DOCtor form with four physician global estimates for overall status, inflammation, damage, and symptoms based on neither inflammation nor damage. | 25150341 |
| Inflammation, Fibromyalgia, Chronic pain, Somatization | Altered Intercellular Communication | We sought to clarify a global summary of patient status by supplementing DOCGL with three additinal separate (0-10) physician global estimates for inflammation (DOCINF), damage (DOCDAM), and neither inflammation nor damage (DOCNON) (often fibromyalgia, but may be other chronic pain or somatization syndromes). | 25150341 |
| Inflammation | Altered Intercellular Communication | These data indicate face validity of the three physician global estimates on subscales for inflammation, damage, and symptoms due to neither inflammation nor damage. | 25150341 |
| Inflammation, Demyelination | Altered Intercellular Communication | Stereotactic brain biopsy revealed acute demyelination and B-cell dominated inflammation. | 25150761 |
| Cholecystitis, Inflammation | Altered Intercellular Communication | All 10 AC patients coexisted with GBC harbored "significantly inflamed' gallbladders, and about 83.49% AC patients were judged with "significant inflammation." | 25151466 |
| Autoimmune Diseases, Myositis | Altered Intercellular Communication | Polymyositis/dermatomyositis (PM/DM) is an autoimmune disease characterised by skin and muscle inflammation, internal organ involvement and serum disease-specific autoantibodies. | 25151986 |
| Inflammation, Contracture | Altered Intercellular Communication | Inflammation and skin-involvement are significant contributing factors for the development of contractures. | 25152080 |
| Corneal Neovascularization, Keratitis, Glaucoma, CTCAE, Ocular surface disease | Altered Intercellular Communication | Multivariate Cox regression analysis was performed, which adjusted for: age, sex, risk factors for graft failure (corneal neovascularization, ocular surface disease, glaucoma, active corneal inflammation, anterior synechiae), donor endothelial cell count, and repeat donor size. | 25152499 |
| Inflammation, Nasal Polyps, Common Cold, Allergic | Altered Intercellular Communication | Although polyps seem to be a manifestation of chronic inflammation in both allergic and non-allergic subjects, the pathogenesis of nasal polyposis remains unknown. | 25153104 |
| Hypergammaglobulinemia, Chronic inflammation | Altered Intercellular Communication | Protein electrophoresis revealed hypergammaglobulinemia consistent with chronic inflammation. | 25153278 |
| ARCN1 gene, Inflammation, Comorbidity, Obesity | Altered Intercellular Communication | To characterize the distribution of BMI in a population-based sample of COPD patients and to evaluate the impact of obesity on their health status, exercise tolerance, systemic inflammation and comorbidity. | 25153331 |
| ARCN1 gene, Inflammation, Obesity, Cardiovascular system | Altered Intercellular Communication | Furthermore, obesity affects the clinical manifestations, quality of life and exercise tolerance of COPD patients, and it may contribute to a phenotype characterized by increased systemic inflammation and greater frequency of cardiovascular comorbidity. | 25153331 |
| Inflammatory abnormality of the eye | Altered Intercellular Communication | The authors report two cases of chronic ocular inflammation with a novel sign of a prefoveal white vitreous condensation. | 25153658 |
| Tumor necrosis, Inflammation | Altered Intercellular Communication | Tumor necrosis factor (TNF)-a, a key inflammatory cytokine responding to chronic inflammation of GBC, has been reported to stimulate the expression of VEGF-C in some nonneoplastic cells. | 25154789 |
| Inflammation, Metabolic Syndrome X, ETV3 wt Allele | Altered Intercellular Communication | Studies have shown that both cystatin C and metabolic syndrome (MetS) are associated with inflammation. | 25155006 |
| ARCN1 gene, Inflammation, Chronic Obstructive Airway Disease | Altered Intercellular Communication | Chronic obstructive pulmonary disease (COPD) is associated with local and systemic inflammation. | 25155252 |
| Inflammatory Bowel Diseases, Crohn Disease, Ulcerative Colitis | Altered Intercellular Communication | Crohn's disease (CD) and ulcerative colitis (UC) are the two major forms of inflammatory bowel diseases (IBD), which are defined as relapsing inflammations of the gastrointestinal tract. | 25155925 |
| Inflammation, Diabetic Polyneuropathies, Impaired | Altered Intercellular Communication | Higher levels of soluble CD163 in people with diabetic polyneuropathy suggest that inflammation plays a role in the development of neural impairment. | 25156085 |
| Inflammation, Hypothyroidism, Atherosclerosis | Altered Intercellular Communication | Recent studies have shown associations of hypothyroidism with arterial blood pressure, atherosclerosis, and inflammation. | 25156414 |
| Inflammation, Atherosclerosis, Hypothyroidism, Hypertension, CTCAE, Microcirculatory Bed, GTP-Binding Nuclear Protein Ran, Human | Altered Intercellular Communication | Based on these pathways, there might also be an association between hypothyroidism and retinal arteriolar narrowing (RAN), a marker of microvascular damage from hypertension, atherosclerosis, and inflammation. | 25156414 |
| Inflammation, Hypertension, CTCAE, atherosclerotic | Altered Intercellular Communication | Potential mechanisms explaining this association are long-term hypertension, atherosclerotic processes, and inflammation. | 25156414 |
| Inflammation, Gastritis, Atrophic | Altered Intercellular Communication | There was significantly more inflammation and atrophy in H. pylori-positive patients, but PGV did not influence the grade of gastritis. | 25157752 |
| Inflammation, ovarian neoplasm | Altered Intercellular Communication | Pre-diagnostic serum levels of inflammation markers and risk of ovarian cancer in the prostate, lung, colorectal and ovarian cancer (PLCO) screening trial. | 25158036 |
| ovarian neoplasm | Altered Intercellular Communication | Pre-diagnostic serum levels of 46 inflammation-related biomarkers (11 with a priori hypotheses; 35 agnostic) were measured in 149 incident ovarian cancer cases and 149 matched controls. | 25158036 |
| Inflammation, GYPB gene, Dry Eye Syndromes | Altered Intercellular Communication | In conclusion, dry eye syndrome in SS patients is associated with an altered proteomic profile with dysregulated expression of proteins involved in a variety of important cellular process including inflammation, immunity, and oxidative stress. | 25159733 |
| Inflammation, Arthritis, Obesity | Altered Intercellular Communication | This study suggests that there may be interplay between obesity, inflammation, and otherwise unexplained arthritis and highlights a previously unrecognized complication of childhood obesity. | 25160015 |
| Cholelithiasis, Colitis | Altered Intercellular Communication | Metabolic phenotyping was also able to distinguish between cholelithiasis and colonic inflammation among the heterogeneous non-AP group. | 25160714 |
| Inflammation, Malnutrition, Anemia | Altered Intercellular Communication | No features suggestive of malnutrition, severe anemia, inflammation, or inadequate dialysis were detected. | 25161116 |
| Inflammation, Doxorubicin/Thiotepa/Vinblastine | Altered Intercellular Communication | All BAV patients showed significantly less inflammation (P < 0.001) and an altered intima/media ratio when compared with TAV patients. | 25161185 |
| Inflammation | Altered Intercellular Communication | We hypothesized that Sirt6, which is a nuclear, chromatin-bound protein critically involved in many pathophysiologic processes such as aging and inflammation, may have a role in oxidative stress-induced vascular cell senescence. | 25162034 |
| Pneumonitis, Neoplasms | Altered Intercellular Communication | A variety of 25 cytokines linked to pulmonary inflammation and tumor development were found significantly associated with Asb-workers and MM patients compared with healthy controls. | 25162674 |
| Inflammation, Inflammatory cardiomyopathy | Altered Intercellular Communication | Intramyocardial inflammation is considered an adverse prognostic factor in inflammatory cardiomyopathy (CMi). | 25163698 |
| Myocarditis | Altered Intercellular Communication | In EMBs, myocardial inflammation was assessed by histology and immunohistology. | 25163698 |
| Inflammation, Mucoid degeneration, Hemosiderin | Altered Intercellular Communication | The PCLs were graded histologically in terms of parallel orientation of collagen fibres, mucoid degeneration, inflammation, and haemosiderin deposition. | 25163942 |
| Inflammation | Altered Intercellular Communication | Most commonly, it is the result of epithelial proliferation, but it can also be caused by inflammation or obstruction of the appendix. | 25163976 |
| Inflammation | Altered Intercellular Communication | ER stress may trigger both inflammation and oxidative stress processes. | 25164487 |
| Inflammation, Chronic disease | Altered Intercellular Communication | Therefore, interventions that reduce chronic disease risk factors (i.e., blood pressure, chronic inflammation, and cortisol) are important in this population. | 25164513 |
| Infection, Pneumonia | Altered Intercellular Communication | Pneumonia is an inflammatory condition of lung caused by infections, which may be triggered and exacerbated by PMc exposure. | 25164925 |
| Inflammation, Colorectal Carcinoma | Altered Intercellular Communication | Inflammation is a major risk factor for development of colorectal cancer (CRC). | 25166592 |
| Inflammation | Altered Intercellular Communication | Prostaglandin synthase cyclooxygenase-2 (COX-2) encoded by the PTGS2 gene is the rate limiting enzyme in prostaglandin synthesis and therefore plays a distinct role as regulator of inflammation. | 25166592 |
| Airway structure, Asthma | Altered Intercellular Communication | However, the relationship between exhaled H2 S and airway inflammation phenotypes in asthma remains unclear. | 25168466 |
| neutrophilic, Inflammation | Altered Intercellular Communication | The eosinophilic, neutrophilic, mixed granulocytic and paucigranulocytic inflammation groups included 57 (38.5%), 28 (18.9%), 23 (15.5%) and 40 (27%) subjects, respectively. | 25168466 |
| Airway structure, Asthma | Altered Intercellular Communication | Exhaled H2 S may be a useful marker of airway inflammation in asthma. | 25168466 |
| Pain Distress Question, Inflammation, Knee pain | Altered Intercellular Communication | To assess the association between pain mechanisms (sensitization) and biochemical markers for cartilage, bone, and inflammation in patients with knee pain. | 25168637 |
| Inflammation, Central pain | Altered Intercellular Communication | This study showed significant correlations between central pain sensitization and CRPM as a possible measure for chronic inflammation. | 25168637 |
| Inflammation, Fibrosis Assessment | Altered Intercellular Communication | Liver fibrosis stage and inflammation grade were evaluated by Metavir and Scheuer scoring systems, respectively. | 25168642 |
| Fibrosis Assessment, Hepatitis | Altered Intercellular Communication | The severity of liver inflammation was independently related to moderate to severe fibrosis (F >=2). | 25168642 |
| Fibrosis, Liver, Hepatitis | Altered Intercellular Communication | Liver inflammation is closely related to the development of moderate to severe liver fibrosis. | 25168642 |
| Inflammation, Fibrosis Assessment, Fatty degeneration | Altered Intercellular Communication | These glycans also correlated significantly with lobular inflammation, ballooning, and fibrosis, but not with steatosis. | 25168691 |
| Neuromyelitis Optica, Myelitis, Transverse, N-nitrosomorpholine, Optic Neuritis | Altered Intercellular Communication | Neuromyelitis optica (NMO) is an autoimmune inflammatory condition of the central nervous system that is characterized by circulating anti-aquaporin-4 antibodies, transverse myelitis and optic neuritis. | 25169022 |
| Inflammation, Atherosclerosis | Altered Intercellular Communication | Increased microvascularization and vessel permeability associate with active inflammation in human atheromata. | 25170063 |
| Hereditary Autoinflammatory Diseases, Inflammation, Ventricular arrhythmia, Atherosclerosis, Brucellosis, Familial Mediterranean Fever | Altered Intercellular Communication | Familial Mediterranean Fever (FMF) is a hereditary autoinflammatory disease associated with subclinical inflammation, which includes atherosclerosis arising from endothelial inflammation, which in turn increases the risk of atrial or ventricular arrhythmias. | 25170297 |
| Prostate carcinoma, prostatitis | Altered Intercellular Communication | Prostate volume index and chronic inflammation of the prostate type IV with respect to the risk of prostate cancer. | 25170543 |
| Inflammation, Injury of cardiac valve, Electrocardiogram: myocardial infarction (finding), No-Reflow Phenomenon, Neurocirculatory Asthenia | Altered Intercellular Communication | Improved endothelial function, reduced low grade inflammation and decreased thrombotic diathesis might reduce cardiac injury, diffuse cardiac necrosis, myocardial infarction and no-reflow phenomenon. | 25170586 |
| Barrett Esophagus, Inflammation, Gastro-esophageal reflux disease with esophagitis, Intestinal metaplasia | Altered Intercellular Communication | Reflux esophagitis (RE) is characterized by inflammation of the squamous epithelium (SQ) of the esophagus and may progress to Barrett's esophagus (BE) characterized by intestinal metaplasia. | 25170842 |
| Inflammation | Altered Intercellular Communication | The role of inflammation in this transition has been postulated but lacks experimental evidence. | 25170842 |
| Kidney Failure, Chronic, Inflammation, Immunologic Deficiency Syndromes | Altered Intercellular Communication | End-stage renal disease (ESRD) is simultaneously associated with immune activation, systemic inflammation and immune deficiency. | 25171218 |
| Neoplasms, Autoimmune limbic encephalitis | Altered Intercellular Communication | Autoimmune limbic encephalitis is an inflammatory condition often associated with an underlying neoplasm. | 25171259 |
| Inflammation, Ulcerative Colitis | Altered Intercellular Communication | Attenuated expression of BRINP3 in UC was independent of current inflammation, unrelated to phenotype or treatment, and remained low at rebiopsy an average of 22 months later. | 25171508 |
| Inflammation | Altered Intercellular Communication | Low levels of this gene could predispose or contribute to the maintenance of the characteristic mucosal inflammation seen in this condition. | 25171508 |
| Crohn Disease, Gastrointestinal inflammation | Altered Intercellular Communication | These Th17 cells are considered important in intestinal inflammation, such as seen in Crohn's disease (CD). | 25172498 |
| Forsythia | Altered Intercellular Communication | Furthermore, hemoglobin levels were associated with the detection of T. forsythia and neutrophil activation/inflammation markers. | 25173070 |
| Inflammation, Injury of liver | Altered Intercellular Communication | Our results suggested that decreased serum fibronectin levels in patients with ACHBLF were correlated to hepatic injury and inflammation. | 25173344 |
| Inflammation, Choline Dehydrogenase, Mitochondrial | Altered Intercellular Communication | The aim of this study was to determine whether physical activity level was associated with inflammation or insulin resistance during a 5-year period in outpatients with known CHD. | 25173442 |
| Inflammation | Altered Intercellular Communication | Lipoprotein-associated phospholipase A2 (Lp-PLA2) has been hypothesized to be involved in atherogenesis through pathways related to inflammation. | 25173516 |
| Fibrosis Assessment | Altered Intercellular Communication | Thus, periostin might play an important role in a vicious circle (aging-fibrosis-inflammation-aging) of heart through promoting myocardial fibrosis and cardiomyocyte senescent simultaneously. | 25173938 |
| Inflammation, Carcinogenesis, Injury of liver | Altered Intercellular Communication | Haematopoietic cell-derived Jnk1 is crucial for chronic inflammation and carcinogenesis in an experimental model of liver injury. | 25173965 |
| Inflammation, Liver Cirrhosis | Altered Intercellular Communication | Inflammation is a common event in the pathogenesis of liver cirrhosis. | 25173967 |
| Inflammation, Liver Cirrhosis | Altered Intercellular Communication | The inflammasome pathway has acquired significant relevance in the pathogenesis of inflammation, but its role in the inflammatory response in patients with decompensated cirrhosis remains unexplored. | 25173967 |
| Acute inflammation | Altered Intercellular Communication | Evaluation of hepatocyte growth factor as a local acute phase response marker in the bowel: the clinical impact of a rapid diagnostic test for immediate identification of acute bowel inflammation. | 25174881 |
| Inflammation | Altered Intercellular Communication | It has high affinity to sulfated glycan, and this binding affinity is lost during chronic inflammation. | 25174881 |
| Acute inflammation | Altered Intercellular Communication | HGF is a good local acute phase response marker of acute bowel inflammation. | 25174881 |
| Intraocular inflammation, Aniridia | Altered Intercellular Communication | Compared to patients with KPro retention, those requiring KPro explantation were associated with aniridia (P = .0038), sterile keratolysis (P < .001), retroprosthesis membrane (P = .02), and intraocular inflammation (P = .04). | 25174898 |
| Alzheimers Disease | Altered Intercellular Communication | One case of Alzheimer's disease for which a brain biopsy was performed showed CAA-related inflammation. | 25175137 |
| Inflammation, Fever, CTCAE, Brucellosis, Autosomal Recessive Disorder, Familial Mediterranean Fever | Altered Intercellular Communication | Familial Mediterranean fever (FMF) is an autosomal recessive disorder characterized by periodic fever and serosal inflammation. | 25175140 |
| Inflammation, Mesothelioma | Altered Intercellular Communication | Because asbestos can cause chronic inflammation at the pleural and peritoneal surfaces we hypothesised that NSAID and COX-2 inhibitors would inhibit the development of asbestos-induced mesothelioma. | 25175318 |
| ARCN1 gene, Inflammation | Altered Intercellular Communication | Mobile-phone-based home exercise training program decreases systemic inflammation in COPD: a pilot study. | 25175787 |
| Inflammation | Altered Intercellular Communication | Decreased systemic inflammation may contribute to these clinical benefits. | 25175787 |
| Communicable Diseases, Neurologic Deficits, Inflammation, Deformity of facial bone | Altered Intercellular Communication | The majority of complications were infection and inflammation (36.4%), followed by neurological deficit (24.0%), physiological dysregulation (11.6%) and facial bone deformity (8.3%). | 25176495 |
| Arthritis | Altered Intercellular Communication | Distribution of interleukin-10 family cytokines in serum and synovial fluid of patients with inflammatory arthritis reveals different contribution to systemic and joint inflammation. | 25178435 |
| Inflammation | Altered Intercellular Communication | Therefore, IL-19 seems to be involved mainly in the joint inflammation, whereas IL-20 and IL-24 appear to participate mainly in the systemic responses. | 25178435 |
| Primary gout, Gout | Altered Intercellular Communication | Based on the role of apoA-I in anti-inflammation, our observational data in acute gout support the hypothesis that apoA-I expression can be induced under the condition of a high concentration of UA and its elevated level may be implicated in the spontaneous resolution of acute gouty arthritis. | 25178483 |
| Inflammation, Electrocardiogram: myocardial infarction (finding), Angina Pectoris | Altered Intercellular Communication | Differences determined by optical coherence tomography volumetric analysis in non-culprit lesion morphology and inflammation in ST-segment elevation myocardial infarction and stable angina pectoris patients. | 25178981 |
| Inflammation | Altered Intercellular Communication | The novel OCT-based 3-D quantification of the FC and macrophage demonstrated thinner FC thickness and larger areas of TCFA coupled with more inflammation in non-culprit sites of STEMI compared with SAP. | 25178981 |
| Inflammation, Heart failure, Bipolar Disorder | Altered Intercellular Communication | Depressive symptoms and the relationship of inflammation to physical signs and symptoms in heart failure patients. | 25179036 |
| Inflammation, Heart failure, Bipolar Disorder | Altered Intercellular Communication | Depressive symptoms in patients with heart failure can affect the relationship between physical signs and symptoms and inflammation. | 25179036 |
| Inflammation, Heart failure, Bipolar Disorder | Altered Intercellular Communication | Both depressive symptoms and inflammation should be considered along with physical signs and symptoms in patients with heart failure. | 25179036 |
| Inflammation, Atherosclerosis | Altered Intercellular Communication | Atherosclerosis is a disease characterized by inflammation in the arterial wall. | 25179298 |
| Refractory anemias, Inflammation, Rheumatoid Arthritis | Altered Intercellular Communication | Evidences indicate that oxidative stress and inflammation are important processes in the development of destructive synovial tissue in rheumatoid arthritis (RA). | 25179377 |
| Inflammation | Altered Intercellular Communication | The two major bioscavenger enzymes that are associated with inflammation and oxidative stress are human-butyrylcholinesterase (BuChE) and paraoxonase-1 (PON-1). | 25179377 |
| Refractory anemias, Rheumatoid Arthritis, Inflammation, Hyperplasia | Altered Intercellular Communication | Rheumatoid arthritis (RA) is characterized by chronic synovial inflammation and hyperplasia. | 25179850 |
| Inflammation, Osteopenia | Altered Intercellular Communication | Cements that tend to leave more undetected excess have a higher prevalence for peri-implant inflammation and cause a more severe peri-implant bone loss. | 25180598 |
| Cessation of life, Inflammation | Altered Intercellular Communication | Proteinase 3-dependent caspase-3 cleavage modulates neutrophil death and inflammation. | 25180606 |
| Cessation of life, Inflammation, Peritonitis | Altered Intercellular Communication | Pharmacological inhibition or knockdown of PR3 delayed neutrophil death in vitro and consistently delayed neutrophil death and augmented neutrophil accumulation at sites of inflammation in a murine model of peritonitis. | 25180606 |
| Inflammation, Fibrosis Assessment, IgG4-Related Sclerosing Disease | Altered Intercellular Communication | IgG4-related disease (IgG4-RD) is a new disease entity characterized by type 2 helper T (Th2)-dominant inflammation and progressive fibrosis. | 25180614 |
| Inflammation, Fibrosis Assessment | Altered Intercellular Communication | In conclusion, we found the remarkable infiltration of C/EBPa(+)M2 macrophages in cases of chronic inflammation with fibrosis, including IgG4-RD. | 25180614 |
| Inflammation, Osage language, Cardiovascular Diseases | Altered Intercellular Communication | The increment of systemic inflammation in OSA has been considered as the major pathogenic mechanism leading to cardiovascular diseases. | 25180986 |
| Inflammation, Osage language, Cardiovascular Diseases | Altered Intercellular Communication | Elevated plasma MPO activity and sTNF-R1 levels in the OSA patients indicate increased systemic inflammation and oxidative stress which might contribute to the higher incidence of cardiovascular diseases. | 25180986 |
| Granulomatous inflammation, Myxoma | Altered Intercellular Communication | Histopathologic examination of valve tissue and the myxoma revealed granulomatous inflammation and large numbers of organisms in most specimens. | 25181311 |
| Fibrosis Assessment, Hepatitis B, Hepatitis | Altered Intercellular Communication | Soluble CD163 is an indicator of liver inflammation and fibrosis in patients chronically infected with the hepatitis B virus. | 25181653 |
| Fibrosis Assessment, Hepatitis, Hepatitis B, Chronic | Altered Intercellular Communication | The aim of the current study was to investigate whether serum sCD163 levels correlate with liver inflammation and fibrosis in patients with chronic hepatitis B virus (HBV) infection. | 25181653 |
| Deafness, Sudden | Altered Intercellular Communication | The slight asymmetry might indicate a greater vulnerability of the left inner ear in women, suggesting hormonal factors in the genesis of sudden deafness. | 25181661 |
| Inflammation, Cardiovascular Diseases, Cyclophosphamide/Vincristine/Dacarbazine Regimen, Congestive heart failure, Dystrophic calcification, Chronic heart failure | Altered Intercellular Communication | Inflammation and dystrophic calcification have been associated with cardiovascular disease (CVD) and chronic heart failure (CHF). | 25181915 |
| Inflammation | Altered Intercellular Communication | Dietary fats have been shown to promote the translocation of bacterial endotoxins from the gut into circulation, which may induce systemic inflammation and modulate the inflammatory response of circulating immune cells. | 25182144 |
| Inflammation, Encephalopathy, CTCAE 5.0, DHDDS gene | Altered Intercellular Communication | HMGB1, as an important late mediator of inflammation, is involved in the inflammatory reaction in delayed encephalopathy, and is positively correlated with HDS and ADL scores, indicating that it can be used as one of the major indicators in monitoring carbon monoxide poisoning. | 25182828 |
| vascular inflammations, GDC AJCC Clinical Stage Terminology | Altered Intercellular Communication | Platelet-derived products appear to dominate the inflammatory response during ACS, adding to the emerging evidence that ACS per se may promote vascular inflammation. | 25183015 |
| Inflammation | Altered Intercellular Communication | Serum ALT and AST, but not plasma M30 showed a significant trend with increasing grades of ballooning and lobular inflammation. | 25184298 |
| IgG4-Related Sclerosing Disease, Pseudolymphoma, Immunoglobulin G4-Related Disease, Orbital Pseudotumor | Altered Intercellular Communication | To determine the proportion of idiopathic orbital inflammation (IOI) and orbital benign lymphoid hyperplasia (OBLH) accounted for by immunoglobulin (Ig)G4-related orbital disease (IgG4-ROD) using the comprehensive diagnostic criteria for IgG4-related disease published by Umehara et al and the consensus diagnostic criteria published by Deshpande et al. | 25185258 |
| Lymphoid hyperplasia, IgG4-Related Sclerosing Disease, Orbital Pseudotumor | Altered Intercellular Communication | An analysis of IgG4-related disease (IgG4-RD) among idiopathic orbital inflammations and benign lymphoid hyperplasias using two consensus-based diagnostic criteria for IgG4-RD. | 25185258 |
| Inflammation, Molluscum Contagiosum, Sezary Syndrome, Eczema | Altered Intercellular Communication | We report the original observation of a patient with stage IV Sezary syndrome, who presented multiple molluscum contagiosum, spread and surrounded by a pale halo, without inflammation, eczema or disappearance of melanocytes. | 25186152 |
| Inflammation, Molluscum Contagiosum | Altered Intercellular Communication | This halo could be due to the secretion of a protein by molluscum contagiosum inhibiting inflammation around this MC. | 25186152 |
| Inflammation | Altered Intercellular Communication | These features might help to quantify the degree of inflammation in inflammatory skin conditions. | 25186162 |
| Inflammation, Hyperglycemia, Diabetes Mellitus | Altered Intercellular Communication | Inflammation and hyperglycemia mediate Deaf1 splicing in the pancreatic lymph nodes via distinct pathways during type 1 diabetes. | 25187368 |
| Inflammation, Hyperglycemia | Altered Intercellular Communication | Inflammation and hyperglycemia independently drive Deaf1 splicing through activation of the splicing factors Srsf10 and Ptbp2, respectively. | 25187368 |
| Inflammation | Altered Intercellular Communication | Inflammation induced by injection of activated splenocytes increased Deaf1-Var1 and Srsf10, but not Ptbp2, in the PLNs of NOD.SCID mice. | 25187368 |
| Inflammation, Choroidal and Ciliary Body Melanoma pT1d TNM Finding v8, Hyperglycemia | Altered Intercellular Communication | These data suggest that during the progression of T1D, inflammation and hyperglycemia mediate the splicing of DEAF1 and loss of PTA expression in LNSCs by regulating the expression of SRSF10 and PTBP2. | 25187368 |
| Inflammation | Altered Intercellular Communication | Clinical evaluation of multiple inflammation biomarkers for diagnosis and prognosis for patients with systemic inflammatory response syndrome. | 25187630 |
| Inflammation, Systemic Inflammatory Response Syndrome | Altered Intercellular Communication | A multiplexed biomarker bundle consisting of nine different inflammation markers was evaluated regarding their diagnostic and prognostic performances in 159 adult systemic inflammatory response syndrome (SIRS) patients enrolled at the emergency department. | 25187630 |
| Inflammation, Rheumatoid Arthritis | Altered Intercellular Communication | Cumulative inflammation associates with asymmetric dimethylarginine in rheumatoid arthritis: a 6 year follow-up study. | 25187642 |
| Refractory anemias, Inflammation | Altered Intercellular Communication | Two hundred and one RA patients [155 females, median age 67 years (range 59-73)] were assessed at baseline (2006) for the presence of classical CVD risk factors and determination of systemic inflammation by CRP and ESR. | 25187642 |
| Hidradenitis Suppurativa, Inflammation | Altered Intercellular Communication | Hidradenitis suppurativa (HS) is a disease characterized by chronic follicular occlusion and secondary inflammation of the apocrine glands. | 25188457 |
| Inflammation, Cryptitis | Altered Intercellular Communication | The most common finding on small intestinal biopsy (13/25 cases, 52%) was villous blunting, expansion of the lamina propria by mixed but predominantly mononuclear inflammation, and neutrophilic cryptitis with or without crypt microabscesses. | 25188868 |
| Inflammation, Acute GVH disease | Altered Intercellular Communication | Increased crypt apoptosis with minimal inflammation, resembling acute graft-versus-host disease, was observed in 4 cases (16%). | 25188868 |
| Inflammation, Intraepithelial Lymphocytosis, Acute GVH disease | Altered Intercellular Communication | Findings in non-small intestinal sites were variable and included mixed active and chronic inflammation, chronic inflammation alone, intraepithelial lymphocytosis, and increased apoptosis resembling acute graft-versus-host disease. | 25188868 |
| Inflammation, Enteritis | Altered Intercellular Communication | In summary, AIE most commonly presents as an active enteritis with villous blunting and expansion of the lamina propria by mixed inflammation. | 25188868 |
| Inflammation, Ketoacidosis | Altered Intercellular Communication | This inflammation led to poor insulin absorption, poorly controlled blood glucose and subsequently to ketoacidosis. | 25188930 |
| Inflammation, Primary malignant neoplasm, Carcinoma of lung, Inflammatory disorder | Altered Intercellular Communication | Similar fibroblast phenotypes in inflammatory diseases and cancer tissues suggested a correlation between inflammation and cancer and implied a common mechanism underlying the formation of fibroblasts in inflammatory diseases and lung cancer. | 25189096 |
| Inflammation, Cyclophosphamide/Vincristine/Dacarbazine Regimen, Cardiovascular Diseases | Altered Intercellular Communication | Adipose tissue inflammation and perturbation of adipokine secretion may contribute to the pathogenesis of cardiovascular diseases (CVD). | 25189569 |
| vascular inflammations | Altered Intercellular Communication | EETs are potent endogenous vasodilators and inhibitors of vascular inflammation. | 25189712 |
| Klinefelter Syndrome, SLC22A5 gene | Altered Intercellular Communication | We can presume that adult men with SCD showed clinical hypoandrogenism with normal testicular hormonal function, a fact inconsistent with the hypothesis of primary hypogonadism. | 25190051 |
| Tumor necrosis, Fibrosis Assessment, Inflammation | Altered Intercellular Communication | Independent pathologic review of tumor necrosis and normal liver tissue grading of fibrosis and inflammation after resection was performed. | 25190114 |
| Inflammation, Fibrosis Assessment | Altered Intercellular Communication | In nontumor-bearing liver, fibrosis grade (0-4) and inflammation score (0-4) was 2 or less in all specimens. | 25190114 |
| Liver carcinoma | Altered Intercellular Communication | The C-reactive protein/albumin ratio, a novel inflammation-based prognostic score, predicts outcomes in patients with hepatocellular carcinoma. | 25190127 |
| FAM126A gene | Altered Intercellular Communication | The CRP/Alb ratio might be an independent prognostic marker in patients with HCC, and may have comparable prognostic ability to other established inflammation-based prognostic scores. | 25190127 |
| Primary malignant neoplasm | Altered Intercellular Communication | The prognostic value of this novel inflammation-based prognostic score needs to be verified in patients with other types of cancer. | 25190127 |
| Inflammation, Bacterial Infections | Altered Intercellular Communication | Similar to mucin O-glycosylation, protein N-glycosylation appears to be regulated primarily as a secondary effect of bacterial infection and inflammation rather than the CF pathogenesis in sputum. | 25190359 |
| Inflammation, Metabolic Syndrome X, Atherosclerosis, Chronic inflammatory disorder, Spondylitis | Altered Intercellular Communication | Since ankylosing spondylitis (AS) is a chronic inflammatory disease associated with accelerated atherosclerosis, we aimed to assess whether OPG levels correlate with disease activity, systemic inflammation, metabolic syndrome, adipokines and biomarkers of endothelial cell activation in patients with AS undergoing TNF-a antagonist therapy. | 25190453 |
| Inflammation, Metabolic Syndrome X | Altered Intercellular Communication | Correlations of OPG levels with disease activity, clinical characteristics, systemic inflammation, metabolic syndrome features, adipokines and biomarkers of endothelial activation were assessed. | 25190453 |
| Inflammation, Depressive disorder, Metabolic Syndrome X, Schizophrenia | Altered Intercellular Communication | Metabolic syndrome and inflammation markers in patients with schizophrenia and recurrent depressive disorder. | 25191767 |
| Inflammation, Metabolic Syndrome X | Altered Intercellular Communication | The levels of inflammation markers (i.e., C-reactive protein and PAI-1) were significantly higher among patients with metabolic syndrome. | 25191767 |
| Schizophrenia, Inflammation, Depressive disorder, Metabolic Syndrome X | Altered Intercellular Communication | Patients with schizophrenia and recurrent depressive disorder demonstrate a high prevalence of metabolic syndrome that is also related to inflammation processes. | 25191767 |
| ovarian neoplasm, Pelvic Inflammatory Disease | Altered Intercellular Communication | Pelvic inflammation and the pathogenesis of ovarian cancer: a cohort study. | 25191876 |
| ovarian neoplasm, Malignant Neoplasms, Pelvic Inflammatory Disease | Altered Intercellular Communication | The aim of this study was to determine whether pelvic inflammation contributes to the pathogenesis of ovarian cancer or other malignancies. | 25191876 |
| Malignant Neoplasms, Pelvic Inflammatory Disease | Altered Intercellular Communication | Eight hundred eighty-eight women with past pelvic inflammation, as diagnosed by characteristic findings at fertility surgery, and 552 women without were compared for the subsequent development of malignancy, during the period of 1981 to 2012. | 25191876 |
| ovarian neoplasm, Inflammation | Altered Intercellular Communication | The adjusted odds ratio for ovarian cancer, after past inflammation, was 5.56 (95% confidence interval, 0.52-59.40). | 25191876 |
| ovarian neoplasm, Pelvic Inflammatory Disease | Altered Intercellular Communication | Age-adjusted ovarian cancer incidence was significantly elevated among women with previous pelvic inflammation (standardized incidence ratio, 3.99; 95% confidence interval, 1.46-8.68). | 25191876 |
| ovarian neoplasm, Pelvic Inflammatory Disease | Altered Intercellular Communication | The rate of ovarian cancer was not significantly elevated in women with past pelvic inflammation compared with the controls. | 25191876 |
| ovarian neoplasm, Pelvic Inflammatory Disease | Altered Intercellular Communication | However, a significantly increased risk for ovarian cancer was apparent among women with pelvic inflammation when compared with the general population. | 25191876 |
| ovarian neoplasm, Pelvic Inflammatory Disease | Altered Intercellular Communication | Pelvic inflammation may be a contributory factor in the pathogenesis of ovarian cancer. | 25191876 |
| FCGR3A gene | Altered Intercellular Communication | Importantly, a single dose of NP001 caused a dose-dependent reduction in expression of monocyte CD16, a marker of monocyte activation/inflammation. | 25192333 |
| Amyotrophic Lateral Sclerosis, Inflammation | Altered Intercellular Communication | The potential for modulation of inflammation in the context of ALS disease progression will require further study with long-term follow-up. | 25192333 |
| Keratitis, Infiltration | Altered Intercellular Communication | Because other signs of corneal inflammation, such as stromal infiltration and ciliary injection, were lacking, the condition was left untreated. | 25192915 |
| Cardiac Arrest, Reperfusion Injury | Altered Intercellular Communication | The whole body ischaemia-reperfusion after cardiac arrest (CA) induces a systemic inflammation-reperfusion response. | 25193800 |
| Degenerative polyarthritis, Inflammation | Altered Intercellular Communication | Interleukin 8 (IL-8), as a member of the CXC chemokine family, has a regulatory role in joint inflammation and cartilage degradation, and contribute to the pathophysiology of osteoarthritis. | 25194757 |
| Inflammation, Acute infectious disease | Altered Intercellular Communication | There is a positive correlation between the parameters of inflammation and glucoregulation in diabetics with acute infection. | 25195343 |
| Inflammation, Fibrosis Assessment, Prediabetes syndrome, Skeletal muscle structure | Altered Intercellular Communication | When well-matched for clinical parameters (BMI, total adiposity, or prevalence of prediabetes/type 2 diabetes), no significant differences were observed among groups in terms of skeletal muscle, hepatic, or adipose tissue insulin sensitivity, the amount of liver fat by (1)H-MRS, or the severity of histological inflammation, ballooning, or fibrosis. | 25195551 |
| metabolic disturbance | Altered Intercellular Communication | Impact of metabolic disturbances and malnutrition-inflammation on 6-year mortality in Japanese patients undergoing hemodialysis. | 25196142 |
| Sepsis, Inflammation, Breast Fibrocystic Change, Non-Proliferative Type, Communicable Diseases | Altered Intercellular Communication | Our results suggest predominance of a non-proliferative effector subset of gdT cells in patients with sepsis, which retain functional activity and may contribute towards the host response to inflammation and infection. | 25196852 |
| Primary malignant neoplasm, Chronic sinusitis, Craniosynostosis, Cancer of Nasopharynx | Altered Intercellular Communication | Although epidemiological and laboratory studies report that chronic inflammatory conditions contribute to the pathogenesis of cancer, it remains controversial whether chronic rhinosinusitis (CRS) results in nasopharyngeal cancer (NPC). | 25197911 |
| Malignant Lesion, Neoplasms | Altered Intercellular Communication | The median ADC value for the malignant lesions was 0.6 x 10(-3), whereas that for the inflammatory conditions was 1.6 x 10(-3) and that for the benign tumors was 1.5 x 10(-3) with a highly significant difference (p < .001). | 25198015 |
| Inflammation, myonecrosis, Reperfusion Injury | Altered Intercellular Communication | The postprocedural state after cardiac revascularization interventions is characterized by intense inflammation and activation of inflammatory cytokines due to myonecrosis and ischemia/reperfusion injury. | 25198111 |
| Hip joint pain, Bursitis | Altered Intercellular Communication | We hypothesised that trochanteric bursitis may not however have an inflammatory component and that accordingly, bursal inflammation has no role in lateral hip pain. | 25198303 |
| Inflammation, Long-term | Altered Intercellular Communication | Nineteen eyelids had implant-related complications: 7 with cyst formation, 7 with exposure/rejection, 2 with long-term pain, 2 with transient inflammation, and 3 with irregular implant contour. | 25198397 |
| Inflammation, Fibrosis Assessment | Altered Intercellular Communication | In addition, target gene prediction showed that these five altered miRNAs are involved in affecting various aspects of cardiac or vascular remodeling, especially in the pathway involving inflammation and fibrosis. | 25198728 |
| Inflammation, Dentigerous Cyst | Altered Intercellular Communication | There is an association between persistent, prolonged inflammation of a primary tooth and the development of an inflammatory dentigerous cyst involving the succedaneous tooth. | 25198956 |
| Inflammation, Colorectal Carcinoma, Colonic Polyps | Altered Intercellular Communication | Moreover, the cell wall of this bacterium may have low pathogenicity as well as cause chronic inflammation in the large intestine mucous membrane, colonic polyps, and colorectal cancer. | 25199383 |
| Inflammation, Unknown (origin) (qualifier value), iatrogenic injury, Traumatic injury, Deformity | Altered Intercellular Communication | Its etiology varies, including space occupying lesions, trauma, inflammation, anatomic deformity, iatrogenic injury, and idiopathic and systemic causes. | 25199522 |
| Sepsis, Inflammation, Thrombosis | Altered Intercellular Communication | The adjusted odds ratios for thrombosis were 2.5 (2.4 to 2.6) in patients with systemic inflammatory response syndrome, 3.3 (3.1 to 3.4) in patients with sepsis, and 5.7 (5.4 to 6.1) in patients with severe sepsis, compared with patients without any systemic inflammation. | 25199629 |
| Inflammation, Diffuse Large B-Cell Lymphoma, Chronic inflammation, Aggressive Non-Hodgkin Lymphoma | Altered Intercellular Communication | Diffuse large B-cell lymphoma (DLBCL) associated with chronic inflammation is a recently adopted category of DLBCL, which describes an aggressive B-cell lymphoma raised in the setting of non-immune chronic inflammation. | 25199714 |
| Inflammation, Pancreatic intraepithelial neoplasia | Altered Intercellular Communication | Lactate and taurine remained unchanged in inflammation and in pre-cancerous metaplasia but increased significantly in pancreatic intraepithelial neoplasia to 266 +- 61% (p = 0.0001) and 999 +- 174% (p < 0.00001) of controls, respectively. | 25199993 |
| Inflammation, Pancreatitis, Pancreatic intraepithelial neoplasia, Neoplasms | Altered Intercellular Communication | Based on these findings, we propose that a drop in lipid levels could serve to inform on pancreatitis and cancer-associated inflammation, whereas elevated lactate and taurine could serve to identify the presence of pancreatic intraepithelial neoplasia and invasive tumor. | 25199993 |
| Inflammation, Sleep Apnea, Obstructive, Diabetes Mellitus, Non-Insulin-Dependent | Altered Intercellular Communication | [Lower grade chronic inflammation is associated with obstructive sleep apnea syndrome in type 2 diabetes mellitus]. | 25200039 |
| Inflammation, Sleep Apnea, Obstructive, Diabetes Mellitus, Non-Insulin-Dependent | Altered Intercellular Communication | To investigate whether the existence of obstructive sleep apnea syndrome (OSAS) in patients with type 2 diabetes (T2DM) is associated with low grade chronic inflammation. | 25200039 |
| Inflammation, Disorder of eye due to diabetes mellitus | Altered Intercellular Communication | BMP7 reduces inflammation and oxidative stress in diabetic tubulopathy. | 25200314 |
| Diabetic Nephropathy | Altered Intercellular Communication | Our results demonstrate that BMP7 attenuates tubular pro-inflammatory responses in diabetic kidney disease by suppressing oxidative stress and multiple inflammatory signalling pathways including p38 and p44/42 MAPK. | 25200314 |
| Inflammation | Altered Intercellular Communication | Interleukin-33 (IL-33) is an inflammatory cytokine that is constitutively expressed in barrier tissues such as skin and lung and up-regulated in inflammation. | 25200795 |
| Data types - Address | Altered Intercellular Communication | A growing awareness exists that pro-oxidative state and neuro-inflammation are both involved in AD. | 25201785 |
| Bacterial Translocation, Inflammation | Altered Intercellular Communication | Compared with OHAVR, TAVI was associated with decreases in bacterial translocation and inflammation. | 25202829 |
| Respiratory Hypersensitivity, allergic inflammation | Altered Intercellular Communication | Chronic low dose chlorine exposure aggravates allergic inflammation and airway hyperresponsiveness and activates inflammasome pathway. | 25202911 |
| Airway structure, Respiratory Hypersensitivity | Altered Intercellular Communication | Studies were undertaken to define the effects and mechanisms of chronic low-dose chlorine exposure in the pathogenesis of airway inflammation and airway hyperresponsiveness (AHR). | 25202911 |
| Airway structure | Altered Intercellular Communication | Airway inflammation and AHR were evaluated by bronchoalveolar lavage (BAL) cell recovery and non-invasive phlethysmography, respectively. | 25202911 |
| Airway structure, AHR wt Allele | Altered Intercellular Communication | Chronic low dose chlorine exposure significantly augmented airway inflammation and AHR in OVA-sensitized and challenged mice. | 25202911 |
| Allergic, AHR wt Allele, Inflammation | Altered Intercellular Communication | Chronic low dose exposure of chlorine aggravates allergic Th2 inflammation and AHR potentially through activation of inflammasome danger signaling pathways. | 25202911 |
| Inflammation, Liver damage | Altered Intercellular Communication | Heme oxygenase-1 (HO-1) is an inducible, detoxifying enzyme that is critical for limiting oxidative stress, inflammation, and cellular injury within the CNS and other tissues. | 25202977 |
| Inflammation | Altered Intercellular Communication | The skin biopsy showed a granulomatous inflammation with prominent plasma cells, consistent with granulomatous infiltrate. | 25203547 |
| Inflammation, Chronic Kidney Diseases | Altered Intercellular Communication | Chronic systemic inflammation is common in patients with chronic kidney disease on dialysis (CKD5D) and has been considered a key mediator of the increased cardiovascular risk in this patient population. | 25204316 |
| Sjogrens Syndrome", Inflammation, Disease, PEELING SKIN SYNDROME | Altered Intercellular Communication | The red blood cell distribution width (RDW) and neutrophil/lymphocyte ratio (NLR) are increased in various inflammation related diseases, but their clinical significance in primary Sjogren's syndrome (pSS) has not been reported. | 25204965 |
| Inflammation, Pain Distress Question | Altered Intercellular Communication | Systemic biochemical markers of joint metabolism and inflammation in relation to radiographic parameters and pain of the knee: data from CHECK, a cohort of early-osteoarthritis subjects. | 25205017 |
| Degenerative polyarthritis, Inflammation | Altered Intercellular Communication | To investigate associations of biochemical markers of joint metabolism and inflammation with minimum joint space width (JSW) and osteophyte area (OP area) of knees showing no or doubtful radiographic osteoarthritis (OA) and to investigate whether these differed between painful and non-painful knees. | 25205017 |
| Inflammation, Fibrous, Necrosis | Altered Intercellular Communication | On histologic examination, there were regions of fat necrosis without inflammation or increased vascularity, surrounded by fibrous walls. | 25205027 |
| Bone Cysts, Fibrous, Inflammation, Necrosis | Altered Intercellular Communication | In contrast to previous reports that described a mucoid composition of intracarpal bone cysts with occasional foamy macrophages, our observations support the concept that these lesions reflect a spectrum of fat necrosis and fibrous changes, without inflammation or hypervascularity. | 25205027 |
| Inflammation, Albuminuria | Altered Intercellular Communication | Chronic inflammation despite potent antiretroviral treatment may contribute to higher rates of albuminuria among HIV-infected patients. | 25205472 |
| Sepsis, Pancreatic stone, Inflammation | Altered Intercellular Communication | Pancreatic stone protein/regenerating protein has recently emerged as an interesting diagnostic and prognostic marker of inflammation and sepsis in the clinical field. | 25205512 |
| Orchitis | Altered Intercellular Communication | Autoantibodies against protein disulfide isomerase ER-60 are a diagnostic marker for low-grade testicular inflammation. | 25205753 |
| Azoospermia, Orchitis | Altered Intercellular Communication | In sera from infertile azoospermic patients with histologically confirmed low-grade testicular inflammation, significantly elevated titers of autoantibodies against disulfide isomerase family A, member 3 (ER-60) were found. | 25205753 |
| Communicable Diseases, Inflammation | Altered Intercellular Communication | Infection and inflammation of the genital tract are supposed to be responsible for up to 15% of cases among infertile males. | 25205753 |
| Orchitis | Altered Intercellular Communication | Proteins in lysates of normal testicular tissue were separated by high-resolution 2D gel electrophoresis and probed with sera of 13 patients with histologically confirmed chronic testicular inflammation. | 25205753 |
| Orchitis | Altered Intercellular Communication | The newly established ELISA detected significantly elevated titers of autoantibodies against ER-60 in the sera from infertile men with histologically confirmed chronic testicular inflammation (median 8.6; P < 0.01) compared with the control groups. | 25205753 |
| Inflammation, Acute epididymo-orchitis, Reproductive tract infection | Altered Intercellular Communication | Moreover, elevated levels of anti-ER-60 titers were detected in patients suffering from acute epididymo-orchitis (median 3.3; P < 0.05) as compared with healthy normozoospermic men (median 2.13; P < 0.001), male blood donors with unknown fertility status (median 2.72; P < 0.01), patients with impaired semen quality but no infection/inflammation (median 2.59; P < 0.001) and patients with symptoms of genital tract infections and/or inflammation (median 2.18; P < 0.001). | 25205753 |
| Orchitis | Altered Intercellular Communication | Significantly lower levels of anti-ER-60 antibodies were measured in sera from patients after application of anti-inflammatory pharmacotherapy (median 1.9; P < 0.01) compared with those with histologically confirmed chronic testicular inflammation. | 25205753 |
| Orchitis | Altered Intercellular Communication | Measurement of ER-60 autoantibody titers in serum could be a novel non-invasive marker for the diagnosis of asymptomatic testicular inflammation causing male fertility disturbances. | 25205753 |
| Infertility, Communicable Diseases, Inflammation | Altered Intercellular Communication | and A.M. are supported by the LOEWE focus group 'MIBIE' (Male infertility during infection and inflammation). | 25205753 |
| Inflammation, Cervical lymphadenopathy, Lymphadenopathy, Dirty Bombs, Sinus histiocytosis | Altered Intercellular Communication | Sinus histiocytosis with massive lymphadenopathy (also known as Rosai-Dorfman disease [RDD]) is a benign but chronic cervical lymphadenopathy associated with systemic inflammation. | 25207593 |
| Cocaine Abuse, Dacryoadenitis | Altered Intercellular Communication | A 45-year-old female patient with a long history of cocaine abuse presented with bilateral bacterial dacryoadenitis and upper lid inflammation with purulent discharge from a palpebral wound of the right upper lid. | 25208047 |
| Gastrointestinal inflammation | Altered Intercellular Communication | Our data suggest that during intestinal inflammation, the TNF-a-mediated activation of IRF1 is related to the subsequent suppression of OPN expression, further reducing p-AKT, p-P38, and p-ERK activities and resulting in aggravation of the injury to intestinal epithelial cells. | 25208103 |
| Inflammation | Altered Intercellular Communication | Cystic dilatation within the lacrimal gland is thought to be related to chronic inflammation and scarring of the lacrimal gland ductules. | 25208223 |
| Inflammation, Hemorrhage, Dental Plaque | Altered Intercellular Communication | Following a baseline examination for plaque, gingival inflammation and bleeding, 75 qualified healthy adult males and females, ages 18-70 were selected to participate in the study. | 25208366 |
| Inflammation, Hemorrhage, Dental Plaque | Altered Intercellular Communication | The results showed statistically significant reductions in plaque index, gingival inflammation and bleeding on probing. | 25208366 |
| ARCN1 gene, Chronic Obstructive Airway Disease, Airway structure | Altered Intercellular Communication | Chronic obstructive pulmonary disease (COPD) is associated with eosinophilic airway inflammation in 10-20% of patients. | 25208464 |
| Tyrosine Transaminase Deficiency Disease, Adrenal cortical hypofunction | Altered Intercellular Communication | This remarkable sign is easily checked, and should prompt a higher index of suspicion towards adrenal insufficiency and other hormonal deficiencies. | 25209544 |
| Pituitary Adenoma | Altered Intercellular Communication | However, hormonal changes or the association of PTA with other sellar lesions, such as pituitary adenomas, are extremely rare. | 25211451 |
| Inflammation, Urolithiasis, Chronic pyelonephritis | Altered Intercellular Communication | 108 patients (89 women and 19 men) aged from 18 to 59 years with chronic pyelonephritis (CP) on the background of urolithiasis in a phase of active inflammation were evaluated. | 25211919 |
| Celiac Disease, Inflammation, Autoimmune Diseases | Altered Intercellular Communication | Coeliac disease is an autoimmune disease characterized by inflammation localized to the small bowel, but less is known about systemic signs of inflammation. | 25212572 |
| Celiac Disease, Inflammation | Altered Intercellular Communication | A prolonged systemic inflammation may, in turn, contribute to long-term complications known to be associated with untreated coeliac disease. | 25212572 |
| Necrotizing granulomatous inflammation | Altered Intercellular Communication | A biopsy was taken and it showed transmural granulomatous inflammation. | 25213739 |
| Inflammation, Retinitis Pigmentosa, polychondritis | Altered Intercellular Communication | Relapsing polychondritis (RP) is a rare multisystem disease characterised by progressive inflammation and destruction of cartilaginous structures. | 25213785 |
| Inflammation | Altered Intercellular Communication | Age-related macular degeneration in the aspect of chronic low-grade inflammation (pathophysiological parainflammation). | 25214719 |
| methyldopa, Inflammation | Altered Intercellular Communication | The products of oxidative stress trigger chronic low-grade inflammation (pathophysiological parainflammation) process in AMD patients. | 25214719 |
| methyldopa, Drusen, Inflammation | Altered Intercellular Communication | In early AMD, soft drusen contain many mediators of chronic low-grade inflammation such as C-reactive protein, adducts of the carboxyethylpyrrole protein, immunoglobulins, and acute phase molecules, as well as the complement-related proteins C3a, C5a, C5, C5b-9, CFH, CD35, and CD46. | 25214719 |
| methyldopa, Inflammation, Dryness (characteristic) | Altered Intercellular Communication | The complement system, mainly alternative pathway, mediates chronic autologous pathophysiological parainflammation in dry and exudative AMD, especially in the Y402H gene polymorphism, which causes hypofunction/lack of the protective complement factor H (CFH) and facilitates chronic inflammation mediated by C-reactive protein (CRP). | 25214719 |
| methyldopa, Immune-mediated | Altered Intercellular Communication | Many autoantibodies (antibodies against alpha beta crystallin, alpha-actinin, amyloid, C1q, chondroitin, collagen I, collagen III, collagen IV, elastin, fibronectin, heparan sulfate, histone H2A, histone H2B, hyaluronic acid, laminin, proteoglycan, vimentin, vitronectin, and aldolase C and pyruvate kinase M2) and overexpression of Fcc receptors play role in immune-mediated inflammation in AMD patients and in animal model. | 25214719 |
| Inflammation, Diabetes Mellitus, Non-Insulin-Dependent | Altered Intercellular Communication | Joint calcium-vitamin D supplementation might improve systemic inflammation through decreasing IL-6 and TNF-a concentrations in vitamin D-insufficient people with type 2 diabetes. | 25215557 |
| Inflammation, Vasculitis of large artery, Structure of vasa vasorum | Altered Intercellular Communication | On the basis of the localization of the inflammation, positive TABs were further classified into 4 categories: small vessel vasculitis (SVV), in which inflammation was limited to small periadventitial vessels devoid of muscular coat, with sparing of the temporal artery (32 cases, 9% of the positive biopsies); vasa vasorum vasculitis (VVV), in which inflammation was limited to the adventitial vasa vasorum (23 cases, 6.5% of the positive biopsies); inflammation limited to adventitia (ILA), in which inflammation extended from a strictly perivascular localization to the surrounding adventitia, without medial involvement (25 cases, 7% of the positive biopsies); and transmural inflammation (TMI), in which inflammation crossed the external elastic lamina and extended to the media (274 cases, 77.5% of the positive biopsies). | 25216320 |
| Malignant Neoplasms | Altered Intercellular Communication | The Glasgow Prognostic Score (GPS), an inflammation-based score, has been used to predict the biologic behavior of malignant tumors. | 25216413 |
| Cholecystitis, Fibrosis Assessment, Inflammation, Chronic cholecystitis | Altered Intercellular Communication | Xanthogranulomatous cholecystitis is a rare variant of chronic cholecystitis characterized by severe proliferative fibrosis and accumulation of lipid-laden macrophages in regions of destructive inflammation. | 25216427 |
| Inflammation | Altered Intercellular Communication | High serum concentrations of cortisol were associated with a state of inflammation and independently identified a subgroup of chronic hemodialysis patients at a high mortality risk. | 25216457 |
| Demyelination, Meningitis, Encephalomyelitis, Acute Disseminated | Altered Intercellular Communication | Meningeal inflammation and demyelination in a patient clinically diagnosed with acute disseminated encephalomyelitis. | 25216555 |
| Airway structure, Asthma, Respiratory Hypersensitivity | Altered Intercellular Communication | Comprehensive studies of the pathophysiologic characteristics of elderly asthma, including predominant site of disease, airway inflammation profiles, and airway hyperresponsiveness, are scarce despite their clinical importance. | 25216975 |
| Inflammatory Bowel Diseases, Inflammation | Altered Intercellular Communication | 8/9 had non specific upper gastrointestinal symptoms and 3/9 had rectocolic inflammation evoking inflammatory bowel disease. | 25217048 |
| palladium, Inflammation, Peritonitis | Altered Intercellular Communication | As PD CA125 increases during peritoneal inflammation, we wished to determine whether measuring PD CA125 during peritonitis provided additional information in determining outcome of peritonitis. | 25217152 |
| Inflammation | Altered Intercellular Communication | Aging delays resolution of acute inflammation in mice: reprogramming the host response with novel nano-proresolving medicines. | 25217168 |
| Inflammation | Altered Intercellular Communication | Specialized proresolving lipid mediators (SPMs) are endogenous autacoids that actively promote resolution of inflammation. | 25217168 |
| Inflammation | Altered Intercellular Communication | In this study, we investigated resolution of acute inflammation in aging and the roles of SPMs. | 25217168 |
| Inflammation | Altered Intercellular Communication | These findings provide evidence for age-dependent resolution pathways in acute inflammation and novel means to activate resolution. | 25217168 |
| Inflammation, Ear Inflammation | Altered Intercellular Communication | Staged CI was performed in 6 ears, after radical mastoidectomy with closure of the EAC in 3 ears and after intact canal wall mastoidectomy in 3 ears, due to active inflammation or complications related to otitis media. | 25217370 |
| Airway structure | Altered Intercellular Communication | Airway inflammation and plasma fibrinogen, but not C-reactive protein, were greater in samples with PPM detection (p < 0.001, p = 0.049 and p = 0.261, respectively). | 25218165 |
| Inflammation | Altered Intercellular Communication | Increasing total bacterial load was associated with increasing airway (p < 0.01) but not systemic inflammation (p > 0.05). | 25218165 |
| Airway structure | Altered Intercellular Communication | Samples with high total bacterial loads had significantly higher airway inflammation than both samples without PPM detection and those with lower loads. | 25218165 |
| ARCN1 gene, Inflammation | Altered Intercellular Communication | Airway and systemic inflammation, as measured by fibrinogen, is greater in stable COPD patients with PPMs detected using the culture-independent qPCR technique. | 25218165 |
| Discordance, Inflammation | Altered Intercellular Communication | However, discordance between inflammation and health status was observed. | 25218165 |
| Inflammation, Primary malignant neoplasm | Altered Intercellular Communication | Recent evidence indicates that inflammation is an essential component of pathogenesis and progression of cancer. | 25218270 |
| Inflammation, Malnutrition | Altered Intercellular Communication | Periodontal status, inflammation, and malnutrition in hemodialysis patients - is there a link? | 25218877 |
| Inflammation, Malnutrition, HD Term Type, Periodontal Diseases, Pervasive Development Disorder | Altered Intercellular Communication | Periodontal disease (PDD) was associated with inflammation, malnutrition, and higher mortality in hemodialysis (HD) patients. | 25218877 |
| Inflammation, Malnutrition, Pervasive Development Disorder | Altered Intercellular Communication | Patients with PDD were older; higher percentages of them were smokers, diabetics, had malnutrition, and inflammation. | 25218877 |
| Inflammation, Pervasive Development Disorder, Anemia | Altered Intercellular Communication | The prevalence is higher in malnourished and in inflamed patients; inflammation seems to accompany PDD and to influence anemia response to treatment. | 25218877 |
| Inflammation, Obesity | Altered Intercellular Communication | Obesity in adolescents from urban and rural areas--a comparison of physical fitness and markers of inflammation. | 25219832 |
| Inflammation, Obesity | Altered Intercellular Communication | Obesity entails serious health consequences associated with the development of inflammation in the body and it has an impact on physical fitness. | 25219832 |
| Inflammation, Obesity | Altered Intercellular Communication | Obesity is not only related to the development of inflammation in the body, but it is a condition involving the production of proinflammatory cytokines. | 25219832 |
| Inflammation, Overweight, Obesity | Altered Intercellular Communication | The study demonstrated inferior results of fitness tests and the presence of features of inflammation in adolescents in both age groups, compared with their peers who had no problems with overweight or obesity. | 25219832 |
| Inflammation, Obesity | Altered Intercellular Communication | Young people from rural areas are more at risk of metabolic consequences of obesity than their peers from urban areas, due to poorer fitness and already visible markers of inflammation. | 25219832 |
| Inflammation, Gingiva, Periodontal Diseases | Altered Intercellular Communication | Additionally, previous evidence indicates that GroEL from P. gingivalis may possess biological activities involved in systemic inflammation, especially inflammation involved in the progression of periodontal diseases. | 25220060 |
| Neoplasms, Ulceration, CTCAE, Catheter-Related Inflammation | Altered Intercellular Communication | Infiltration of tumors with greater number of macrophages and gene expression pathways associated with wound healing and up-regulation of pro-inflammatory cytokines suggests that ulceration is associated with tumor-related inflammation. | 25220403 |
| Inflammation, Neoplasms | Altered Intercellular Communication | The relative benefit from interferon reported in patients with ulcerated tumors may reflect modification of signaling pathways involved in inflammation. | 25220403 |
| Inflammation, Osage language, Atherosclerosis, Endothelial dysfunction, Sleep Apnea, Obstructive, Hypertension, CTCAE | Altered Intercellular Communication | Accumulated evidence implicates sympathetic activation as inducing oxidative stress and systemic inflammation, which in turn lead to hypertension, endothelial dysfunction, and atherosclerosis in obstructive sleep apnea (OSA). | 25221387 |
| Inflammation, Osage language | Altered Intercellular Communication | Statins through their pleiotropic properties may modify inflammation, lipid profile, and cardiovascular outcomes in OSA. | 25221387 |
| Inflammation, Pouchitis, Ulcerative Colitis | Altered Intercellular Communication | Of patients with UC, one group (n = 5) was followed longitudinally over the first year after ileostomy closure, another group had pouchitis (n = 15), and another group no inflammation (n = 18). | 25222658 |
| Inflammation, Ulcerative Colitis | Altered Intercellular Communication | Abnormalities were found in TJP expression in the pouch of patients with UC, in particular, increased expression of the pore-forming claudin 2 as an early event in the development of pouch inflammation and an aberrant DC phenotype was characterized in the ileal pouch of patients with UC. | 25222658 |
| Hyperglycemia, Inflammation, Diabetes Mellitus | Altered Intercellular Communication | Diabetes is a metabolic pro-inflammatory disorder characterized by chronic hyperglycaemia and increased levels of circulating cytokines suggesting a causal role for inflammation in its aetiology. | 25222779 |
| Communicable Diseases, Schistosoma haematobium, Cystitis | Altered Intercellular Communication | Pathological changes due to infection with Schistosoma haematobium include cytokine-mediated urinary tract inflammation. | 25223302 |
| Salmonella enterica subsp. salamae, Communicable Diseases, Cystitis | Altered Intercellular Communication | Urinary IL-6 was positively correlated to and IL-10 was negatively correlated to infection intensity and urinary tract inflammation in S. haematobium-infected children. | 25223302 |
| Inflammation, Inflammatory cardiomyopathy, Heart failure | Altered Intercellular Communication | Cardiac inflammation has been suggested to play a critical role in the pathogenesis of inflammatory cardiomyopathy as well as in progressive heart failure (HF). | 25223819 |
| Infarction, Coagulative necrosis, Skeletal muscle structure, Inflammation | Altered Intercellular Communication | A muscle biopsy demonstrated coagulation necrosis in the skeletal muscle with inflammation and infarction in the walls of small blood vessels. | 25224194 |
| Inflammation, Lower Urinary Tract Symptoms, Obesity | Altered Intercellular Communication | Chronic inflammation and obesity may contribute to the genesis or progression of BPH and BPH-associated lower urinary tract symptoms (LUTS). | 25224558 |
| Communicable Diseases, Inflammation | Altered Intercellular Communication | A (99m)Tc-labeled antigranulocyte antibody scintigraphy was negative for infection or inflammation. | 25224667 |
| Communicable Diseases, Inflammation | Altered Intercellular Communication | This should be considered in patients with such bone replacement materials that are increasingly used, in order to avoid false diagnosis of inflammation or infection. | 25224667 |
| Waldenstrom Macroglobulinemia, Portal inflammation, Autoimmune Chronic Hepatitis | Altered Intercellular Communication | Liver biopsies showed a pattern compatible with drug-induced autoimmune hepatitis, featured by severe portal inflammation and lymphoplasmacytic infiltrate. | 25224696 |
| Drug-Induced Liver Disease, Inflammation, Autoimmune Chronic Hepatitis, Necrosis | Altered Intercellular Communication | Severe portal inflammation, prominent portal-plasma cells, rosette formation and severe focal necrosis were significantly more frequent in drug-induced autoimmune hepatitis as compared to drug-induced liver injury. | 25224696 |
| Behavioral and psychological symptoms of dementia, Neurogenic Inflammation, Data types - Address | Altered Intercellular Communication | The findings indicate a relationship between neuroinflammation and neuropsychiatric symptoms in AD in which anti-inflammatory signalling by IL-10 is beneficial from a mental health perspective. | 25224917 |
| Hemangioma, Cavernous, Sarcoidosis, Squamous cell carcinoma, Lymphoma, Fibrous, Orbital Pseudotumor, Central neuroblastoma | Altered Intercellular Communication | Final diagnosis included lymphoma (3), squamous cell carcinoma (1), neuroblastoma (1), amyloid (1), fibrous tissue (1), sarcoidosis (1), cavernous hemangioma (1), and idiopathic orbital inflammation (1). | 25226099 |
| Osteomyelitis, Inflammation, Communicable Diseases | Altered Intercellular Communication | Osteomyelitis is an inflammation of the bone caused by an infection. | 25226718 |
| Asthma, allergic inflammation | Altered Intercellular Communication | Novel immune-regulatory mechanisms in childhood asthma identified increased Treg cells in patients with AA compared with those in HCs but not those in NA and decreased innate immunity genes for patients with AA, the first potentially indicating a counterregulatory mechanism to suppress cytokines yet not sufficient to control allergic inflammation. | 25226851 |
| Inflammation | Altered Intercellular Communication | Very distinctly, patients with NA showed an IL-17-shifted proinflammatory immunity, promoting neutrophil inflammation and less functional Treg cells. | 25226851 |
| Specimen Source Codes - Abscess, Meningitis, Cellulitis | Altered Intercellular Communication | We discuss the case of a 33-year-old woman who presented to our emergency department with the signs and symptoms of meningeal inflammation after being prescribed TMP/SMX 3 days earlier for an abscess with cellulitis. | 25227653 |
| Ascus (fungus), Postcoital bleeding, Uterine Cervicitis | Altered Intercellular Communication | Colposcopy indications were ASCUS and higher lesions at cervical smear, macroscopic suspicious lesions, post-coital bleeding history with suspicious smear, and repeated cervical inflammation. | 25227835 |
| Inflammation | Altered Intercellular Communication | The most common colposcopy indication was ASCUS, and the most common biopsy result was inflammation. | 25227835 |
| Inflammation | Altered Intercellular Communication | Sirtuin 1 (SIRT1) is a class III histone deacetylase that may play a critical role in several biological functions, including lifespan, stress, and inflammation. | 25228047 |
| Inflammation, Osteoporosis | Altered Intercellular Communication | The potential role of inflammation in bone resorption in patients with osteoporosis was also studied. | 25228047 |
| Psoriasis, Metabolic Syndrome X, Hidradenitis Suppurativa, ETV3 wt Allele, Rheumatoid Arthritis, Dermatitis, Chronic inflammatory disorder | Altered Intercellular Communication | IMPORTANCE An association between the metabolic syndrome (MetS) and chronic inflammatory diseases, such as psoriasis or rheumatoid arthritis, has been suggested.Hidradenitis suppurativa (HS), a more localized chronic inflammation of the skin, has been speculated to have a similar association. | 25229996 |
| Inflammation, Demyelinating Diseases | Altered Intercellular Communication | Inflammation was greater in the demyelinating diseases compared to non-neurologic controls. | 25230202 |
| Inflammation, Demyelination | Altered Intercellular Communication | Olfactory bulb/tract axonal loss was most severe in MS where it correlated significantly with the extent of demyelination (r = 0.610, P = 0.009) and parenchymal inflammation (r = 0.681, P = 0.003). | 25230202 |
| Inflammation, Tissue damage, glycation, Hyperglycemia, Infection, Diabetes Mellitus, Chronic disease, Diabetes Mellitus, Non-Insulin-Dependent | Altered Intercellular Communication | Hyperglycemia induces tissue damage and complications by mechanisms that produce advanced glycation end-products (AGEs) and inflammation.To investigate the factors associated with the progression of complications in Type 2 diabetes patients.We recruited 157 patients (110 women and 47 men) with diabetes for more than 5 years who were non-smokers and did not have current infections or chronic diseases. | 25230243 |
| Inflammation, Brain Damage, Chronic, Kidney Diseases, Cardiovascular system | Altered Intercellular Communication | While chronic renal damage is a condition with low-grade inflammation, the potential role of inflammation in kidney disease as a marker of cardiovascular damage is of current interest. | 25230678 |
| Renal Insufficiency, Inflammation, Electrocardiogram: myocardial infarction (finding), Coronary Arteriosclerosis | Altered Intercellular Communication | This study analyzed the relationship between renal dysfunction, chronic inflammation, and extension of coronary atherosclerosis in patients with non-ST-segment elevation myocardial infarction (NSTEMI). | 25230678 |
| Inflammation, Obesity | Altered Intercellular Communication | Metabolic phenotypes of obesity influence triglyceride and inflammation homoeostasis. | 25231836 |
| TG gene, Inflammation, Obesity | Altered Intercellular Communication | Our findings showed that certain types of the metabolic phenotypes of obesity are more favourable modulating phenotypic flexibility after a dynamic fat load test, through TG metabolism and inflammation homoeostasis. | 25231836 |
| Inflammation, Crypt hyperplasia, Villous atrophy | Altered Intercellular Communication | In a significant proportion of the remaining study subjects, duodenal biopsy showed villous atrophy, crypt hyperplasia, and lamina propria inflammation, not accompanied by raised intraepithelial lymphocytes (IELs); this was seen more commonly in cases as compared to controls. | 25231910 |
| Inflammation, Observation Method - Coagulation | Altered Intercellular Communication | In addition to inflammation, coagulation is also induced in vital wounds. | 25233021 |
| Inflammation, Lymphohistiocytosis, Hemophagocytic | Altered Intercellular Communication | Hemophagocytic lymphohistiocytosis (HLH) is a life-threatening condition of uncontrolled immune activation leading to extreme inflammation. | 25233452 |
| Inflammation, Chronic granulomatous disease, Actinomycosis, Communicable Diseases, Abscess | Altered Intercellular Communication | Actinomycosis is an uncommon chronic granulomatous infection first described by Bollinger in 1 877.The infection is caused by actinomyces species and it is characterized by slow contiguous spread and suppurative inflammation, formation of multiple abscesses and sinus tracts with possible drainage of "sulfur granules". | 25233694 |
| Inflammation | Altered Intercellular Communication | It is characterized by diffuse granulomatous inflammation involving various organs including eye. | 25233979 |
| Airway structure | Altered Intercellular Communication | The measurement of the peak exhaled breath temperature (EBT) during multiple tidal breaths offers an easy, non-invasive tool for monitoring airway inflammation. | 25234010 |
| ARCN1 gene, Chronic Obstructive Airway Disease, Airway structure | Altered Intercellular Communication | Chronic obstructive pulmonary disease (COPD) is linked to airway inflammation, which is further aggravated by exacerbations of the disease. | 25234010 |
| ARCN1 gene, Airway structure | Altered Intercellular Communication | The peak exhaled breath temperature, recorded during multiple tidal breaths, increases with an acute exacerbation of COPD, and may be related to accelerated airway inflammation. | 25234010 |
| Inflammation, Malignant Neoplasms | Altered Intercellular Communication | Increased neutrophil-to-lymphocyte ratio (NLR), an index of systemic inflammation, is associated with poor outcome for various types of cancers. | 25234022 |
| Carcinogenic Chlorinated Hydrocarbon, HD Term Type, Inflammation | Altered Intercellular Communication | CHC in HD patients was significantly milder according to stage (P = 0.033), grade and its parameters (periportal activity, portal inflammation and lobular activity) (P < 0.001). | 25234282 |
| Communicable Diseases, Inflammation, Irritation - emotion, Malignant Neoplasms | Altered Intercellular Communication | Inflammation is a critical component of tumorigenesis, and many cancers arise from sites of infection, chronic irritation, and inflammation. | 25234356 |
| Inflammation, Atherosclerosis | Altered Intercellular Communication | Coronary endothelial dysfunction is associated with inflammation and vasa vasorum proliferation in patients with early atherosclerosis. | 25234815 |
| Inflammation, Dental Plaque | Altered Intercellular Communication | Inflammation and vasa vasorum play a pivotal role in the pathophysiology of plaque initiation, development, and complications. | 25234815 |
| Inflammation, Coronary Arteriosclerosis | Altered Intercellular Communication | The current study further supports the role of inflammation and vasa vasorum proliferation in the early stage of coronary atherosclerosis. | 25234815 |
| Inflammation, Fibrosis Assessment | Altered Intercellular Communication | The septal inflammation and fibrosis and airspace organization observed in the first biopsies were replaced by less cellular subpleural fibroelastosis within 3-12 years. | 25234959 |
| Acute Lung Injury, Interstitial inflammation | Altered Intercellular Communication | Interstitial inflammation or acute lung injury may be an initial step in the development of PPFE. | 25234959 |
| Pleurisy, Mesothelial hyperplasia, Malignant Pleural Mesothelioma | Altered Intercellular Communication | Analysis of microRNA expression signatures in malignant pleural mesothelioma, pleural inflammation, and atypical mesothelial hyperplasia reveals common predictive tumorigenesis-related targets. | 25236577 |
| Malignant Pleural Mesothelioma, Pleurisy, Pancreatic Polypeptide, Mesothelial hyperplasia, 1-methyl-1-piperidinomethane sulfonate | Altered Intercellular Communication | Pleural chronic inflammation (PP) and mesothelial hyperplasia (HP) may be critical to the development of malignant pleural mesothelioma (MPM). | 25236577 |
| Inflammation, square decimeter, Obesity | Altered Intercellular Communication | Chronic inflammation is linked to disorders of obesity, insulin resistance and DM2. | 25236830 |
| Inflammation, Peripheral Arterial Diseases | Altered Intercellular Communication | Step-monitored home exercise improves ambulation, vascular function, and inflammation in symptomatic patients with peripheral artery disease: a randomized controlled trial. | 25237048 |
| Inflammation, Sleep Apnea, Obstructive, Osage language | Altered Intercellular Communication | This study investigated morning levels of pentraxin3 (PTX3) as a sensitive biomarker for acute inflammation in patients with obstructive sleep apnea (OSA). | 25237185 |
| Acute inflammation, Osage language | Altered Intercellular Communication | Based on these results, morning PTX3 levels reflect OSA-related acute inflammation and are a useful marker for improvement in OSA following CPAP therapy. | 25237185 |
| Inflammation, Hemorrhage, Calculi, Dental Plaque | Altered Intercellular Communication | Outcome measures were: implant survival; radiographic bone changes; plaque accumulation; bleeding tendency; peri-implant inflammation; presence of dental calculus; biological and technical complications; and patients' satisfaction. | 25237669 |
| Communicable Diseases, Atherosclerosis, Inflammatory disorder, Cerebrovascular accident | Altered Intercellular Communication | CCL11 (Eotaxin-1) is an important inflammatory cytokine belonging to the CC family of chemokines associated with a number of infection or inflammation-related diseases such as atherosclerosis and stroke. | 25237944 |
| Pain Distress Question, Inflammation | Altered Intercellular Communication | Reduction in Pain and Inflammation Associated With Chronic Low Back Pain With the Use of the Medical Food Theramine. | 25237981 |
| Chronic back pain, Inflammation, Back Pain | Altered Intercellular Communication | Treatment with amino acid precursors was associated with substantial improvement in chronic back pain, reduction in inflammation, and improvement in back pain correlated with increased amino acid precursors to neurotransmitters in blood. | 25237981 |
| Neurotransmitters | Altered Intercellular Communication | Neurotransmitter deficiency may be related both to increased turnover rate and inadequate neurotransmitter precursors from the diet, particularly for essential and semi-essential amino acids. | 25237981 |
| Chronic back pain, Inflammation, Back Pain | Altered Intercellular Communication | Treatment with amino acid precursors was associated with substantial improvement in chronic back pain, reduction in inflammation, and improvement in back pain correlated with increased amino acid precursors to neurotransmitters in blood. | 25237981 |
| Inflammation, Thyroid associated opthalmopathies | Altered Intercellular Communication | Novel thermal imaging analysis technique for detecting inflammation in thyroid eye disease. | 25238202 |
| Inflammation, Wells syndrome | Altered Intercellular Communication | Eosinophilic cellulitis is an inflammation of, until now, unknown etiology that was first described by George Wells in 1971. | 25238447 |
| Pain Distress Question, Erythema, Inflammation, Tonsillitis | Altered Intercellular Communication | The treatment group had a statistically significant improvement in the following symptoms compared with the placebo group: pain associated with tonsillitis, pain on swallowing, erythema and inflammation of the pharynx, and tonsil size. | 25238506 |
| Inflammation, Thickened | Altered Intercellular Communication | The LAD showed significant intimal thickening with strong lymphocytic inflammation at the edge of the thickening. | 25239164 |
| Inflammation, Anemia | Altered Intercellular Communication | The role of inflammation, iron, and nutritional status in cancer-related anemia: results of a large, prospective, observational study. | 25239265 |
| Multiple Organ Failure, Inflammation, Immune System Diseases | Altered Intercellular Communication | Severe injury initiates an inflammatory response that can perpetuate immunological dysfunction, uncontrolled inflammation, and subsequent multisystem organ failure. | 25239329 |
| Inflammation, Pancreatic duct | Altered Intercellular Communication | This association is in part due to inflammation from pancreatic ductal obstruction. | 25239347 |
| Inflammation, Pancreatitis, Pancreatic Intraductal Papillary Mucinous Neoplasm, Malignant Neoplasms | Altered Intercellular Communication | We hypothesized that serum pancreatic enzymes, markers of inflammation, are a better predictor of malignancy than pancreatitis in patients with IPMN. | 25239347 |
| Ulcer, Inflammation, diabetic | Altered Intercellular Communication | We have previously reported that topically applied propolis reduces inflammation and improves cutaneous ulcer healing in diabetic rodents. | 25239451 |
| Airway structure, Asthma, Obesity | Altered Intercellular Communication | Obesity is associated with inflammatory processes, which could influence the airway inflammation that is found in patients with asthma. | 25239583 |
| Neurodegenerative Disorders, Impaired cognition, Inflammation, Nerve Degeneration | Altered Intercellular Communication | To address whether underlying neurodegenerative pathology increased susceptibility to acute cognitive change, mice at three stages of neurodegenerative disease progression (ME7 model of neurodegeneration: controls, 12 weeks, and 16 weeks) were assessed for acute cognitive dysfunction upon systemic inflammation induced by bacterial lipopolysaccharide (LPS; 100 mg/kg). | 25239680 |
| Inflammation, Hypoglycemia, Adverse event, Diabetes Mellitus | Altered Intercellular Communication | Association between severe hypoglycemia, adverse macrovascular events, and inflammation in the Edinburgh Type 2 Diabetes Study. | 25239782 |
| Inflammation, Hypoglycemia, Diabetes Mellitus, Non-Insulin-Dependent | Altered Intercellular Communication | To determine whether a history of severe hypoglycemia was associated with an increased risk of subsequent macrovascular events in people with type 2 diabetes and to explore possible mediation of this association by inflammation. | 25239782 |
| Refractory anemias, Inflammation | Altered Intercellular Communication | These findings suggest that RDW can be considered as a surrogate marker of inflammation and, consequently, CV risk in RA patients. | 25239880 |
| Inflammation, Noncommunicable Diseases, Periodontal Diseases | Altered Intercellular Communication | A high frequency of consumption of added sugars is associated with periodontal disease, independent of traditional risk factors, suggesting that this consumption pattern may contribute to the systemic inflammation observed in periodontal disease and associated noncommunicable diseases. | 25240081 |
| Inflammation, Dental Plaque | Altered Intercellular Communication | The incidence of cardiovascular events increases with age and inflammation is generally considered to be the main cause of increased plaque vulnerability. | 25240113 |
| Inflammation | Altered Intercellular Communication | However, the relationship between age and plaque inflammation has not yet been fully clarified. | 25240113 |
| Inflammation, Dental Plaque | Altered Intercellular Communication | The aim of our study was to determine if age-dependent plaque vulnerability is associated with increased plaque inflammation. | 25240113 |
| Inflammation, Dental Plaque | Altered Intercellular Communication | Our data imply that increased plaque vulnerability in the symptomatic elderly patients is associated with increased lipid accumulation and impaired tissue repair, rather than with increased plaque inflammation, compared to younger individuals. | 25240113 |
| Inflammation, Depression, CTCAE | Altered Intercellular Communication | At the same time, increased inflammation might be of importance in the pathophysiology of depression and suicide. | 25240206 |
| Inflammation, Hepatobiliary Disorder, Fibrosis Assessment, Chronic liver disease | Altered Intercellular Communication | The senescent hepatocyte gene signature included changes in cell cycle regulation, morphology, inflammation, signal transduction, metabolism and stellate cell activation, which alongside impaired synthetic function in senescence in vitro were consistent with manifestations of clinical liver disease, suggesting a close relation between hepatocyte senescence and manifestations of chronic liver disease including fibrosis and impaired synthetic function. | 25240687 |
| Neurodegenerative Disorders, Inflammation | Altered Intercellular Communication | A wide range of recent studies have detected inflammation as one of the most influent factors in the appearance and spreading of neurodegenerative brain diseases. | 25240941 |
| Behavior, Periodicity | Altered Intercellular Communication | Hormonal contraception induces artificial cyclicity, which does not, like natural cyclicity, reflect normal, physiological ovarian behaviour. | 25241057 |
| Inflammation, Anastomotic Leak | Altered Intercellular Communication | Accurate prediction of anastomotic leakage after colorectal surgery using plasma markers for intestinal damage and inflammation. | 25241234 |
| Inflammation, Damage, Anastomotic Leak | Altered Intercellular Communication | Markers of inflammation and gut damage might be suitable, as these are hallmarks of anastomotic leakage. | 25241234 |
| Inflammation, Fibrosis Assessment, GDC Disease Response Terminology | Altered Intercellular Communication | In the second cohort of 37 individuals, the DR and the number of HPCs similarly correlated with fibrosis and inflammation after LT. | 25241637 |
| Inflammation, Hemorrhage | Altered Intercellular Communication | An intra-operative cystoscopy revealed a distended bladder showing signs of inflammation with diffuse, widespread bleeding. | 25241838 |
| Carcinoma, Carcinoma of lung | Altered Intercellular Communication | Lung cancer is an inflammation-associated epithelial carcinoma. | 25242236 |
| Inflammation, Disease | Altered Intercellular Communication | Relationship between low grade systematic inflammation and H. pylori should be investigated to find out new predictors for diseases associated with inflammation. | 25243160 |
| Inflammation, Asthma | Altered Intercellular Communication | The effect appears to be associated with non-atopic asthma with general increased systemic inflammation. | 25243322 |
| Inflammation, Hypertension, CTCAE | Altered Intercellular Communication | Oxidative damage and inflammation are both implicated in the genesis of hypertension; however, the mechanisms by which these stimuli promote hypertension are not fully understood. | 25244096 |
| Inflammation, ETV3 wt Allele | Altered Intercellular Communication | Mechanisms involved in the vicious circle of MetS including inflammation, endothelial vasculature and iron metabolism remain to be elucidated. | 25245337 |
| Inflammation, Atherosclerosis | Altered Intercellular Communication | Increased CRP and homocysteine might be a key molecule linking inflammation to oxidative stress in atherosclerosis. | 25245648 |
| Inflammation, glycation, Overweight, Obesity, Diabetes Mellitus, Non-Insulin-Dependent | Altered Intercellular Communication | Impact of glycemic control on advanced glycation and inflammation in overweight and obese patients with type 2 diabetes mellitus. | 25246279 |
| Inflammation, Diabetes Mellitus, Non-Insulin-Dependent, Overweight, Obesity | Altered Intercellular Communication | In this study we tried to investigate the impact of glycemic control on parameters of glycation and inflammation in overweight and obese patients with type 2 diabetes mellitus. | 25246279 |
| Inflammation | Altered Intercellular Communication | But inflammation is a contributing factor for development of AVF stenosis. | 25246339 |
| Chronic Obstructive Airway Disease, Pneumonitis | Altered Intercellular Communication | Systemic and pulmonary inflammation is independent of skeletal muscle changes in patients with chronic obstructive pulmonary disease. | 25246784 |
| ARCN1 gene, Inflammation, Chronic Obstructive Airway Disease | Altered Intercellular Communication | Nutritional depletion is an important manifestation of chronic obstructive pulmonary disease (COPD), which has been related to systemic inflammation. | 25246784 |
| Airway structure | Altered Intercellular Communication | It remains unclear to what degree airway inflammation contributes to the presence or progression of nutritional depletion. | 25246784 |
| ARCN1 gene, Colonization, Airway structure, Muscular Atrophy, Weight decreased | Altered Intercellular Communication | To determine whether airway inflammation and lung bacterial colonization are related to nutritional status or predict progressive weight loss and muscle atrophy in patients with COPD. | 25246784 |
| Airway structure, Colonization | Altered Intercellular Communication | There were no differences in airway inflammation and bacterial colonization in patients with and without nutritional depletion. | 25246784 |
| Airway structure, Colonization, Muscular Atrophy, Nutritional | Altered Intercellular Communication | Nutritional depletion and progressive muscle atrophy are not related to airway inflammation or bacterial colonization. | 25246784 |
| ARCN1 gene, Muscular Atrophy, Pneumonitis | Altered Intercellular Communication | Overspill of pulmonary inflammation is not a key driver of muscle atrophy in COPD. | 25246784 |
| allergic inflammation | Altered Intercellular Communication | The step further to understand the role of cytosolic phospholipase A2 alpha and group X secretory phospholipase A2 in allergic inflammation: pilot study. | 25247183 |
| Airway structure, Exacerbation of asthma, Bacterial Infections | Altered Intercellular Communication | Allergens, viral, and bacterial infections are responsible for asthma exacerbations that occur with progression of airway inflammation. | 25247183 |
| Airway structure | Altered Intercellular Communication | cPLA2 a and sPLA2X are responsible for delivery of arachidonic acid for production of eicosanoids-one of the key mediators of airway inflammation. | 25247183 |
| allergic inflammation | Altered Intercellular Communication | However, cPLA2 a and sPLA2X role in allergic inflammation has not been fully elucidated. | 25247183 |
| allergic inflammation | Altered Intercellular Communication | sPLA2X seems to be one of important PLA2 isoform in allergic inflammation, especially caused by house dust mite allergens. | 25247183 |
| Inflammation, Thrombosis | Altered Intercellular Communication | Our aim was to investigate the association of circulating proteins, the biomarkers of inflammation, blood-brain barrier (BBB) dysfunction, and thrombosis with WMH in non-stroke individuals. | 25248031 |
| Inflammation | Altered Intercellular Communication | These antibodies might be a novel marker of chronic inflammation among CD patients non adhering to GFD. | 25248239 |
| Inflammation | Altered Intercellular Communication | Based on this characteristic appearance, we diagnosed esophageal intramural pseudodiverticulosis and inflammation of a narrow segment of the esophagus. | 25248429 |
| Inflammation, Obesity | Altered Intercellular Communication | Epidemiologic studies examining circulating levels of inflammatory markers in relation to obesity and physical inactivity may aid in our understanding of the role of inflammation in obesity-related cancers. | 25249326 |
| Inflammation, Anxiety, CTCAE 3.0 | Altered Intercellular Communication | Recently, associations between inflammation and anxiety were identified. | 25249351 |
| Juvenile arthritis, Arthritis, Juvenile rheumatoid arthritis | Altered Intercellular Communication | Juvenile Idiopathic Arthritis (JIA) is the most common cause of non-infectious joint inflammation in children. | 25249820 |
| Inflammation, Swelling, Pain Distress Question | Altered Intercellular Communication | Synovial inflammation results in pain, swelling and stiffness. | 25249820 |
| Inflammation, Pain Distress Question | Altered Intercellular Communication | Animal and adult human studies indicate that localized joint-associated inflammation may produce generalized changes in pain sensitivity. | 25249820 |
| Juvenile arthritis, Inflammation | Altered Intercellular Communication | QST data collected from joints were compared within JIA patients: active vs. inactive inflammation; and data from the contralateral thenar eminence were compared between JIA and healthy control cohorts in Europe [EU, (n = 151)] and the US (n = 92). | 25249820 |
| Intestinal metaplasia of gastric mucosa, Epithelial hyperplasia, Dysplasia, Inflammation, Primary malignant neoplasm, Exophytic Polypoid Lesion | Altered Intercellular Communication | Age, gender, histopathological wall thickness of gallbladder, reporting rates of acute inflammation, cholesterolosis, polypoid lesions, epithelial hyperplasia, gastric or intestinal metaplasia, dysplasia and incidental cancer were investigated and compared between patients with and without cholesterolosis. | 25250528 |
| Polyp of gallbladder, Inflammation, Epithelial hyperplasia | Altered Intercellular Communication | Reported histopathological findings were presented as acute inflammation in 46 (10.7%), cholesterolosis in 79 (18.4%), gallbladder polypoid lesions in 7 (1.6%), epithelial hyperplasia in 16 (3.7%), metaplasia of any type in 34 (7.9%) of 429 patients. | 25250528 |
| Wounds and Injuries | Altered Intercellular Communication | Life-threatening traumatic injuries lead to a complex inflammation-driven pathophysiology. | 25250597 |
| Inflammation, Disorder of skeletal system | Altered Intercellular Communication | To assess markers of inflammation and bone turnover at presentation and at resolution of Charcot osteoarthropathy. | 25251588 |
| Limbic Encephalitis, Inflammation | Altered Intercellular Communication | Limbic encephalitis (LE) is an inflammation of structures of limbic system. | 25253433 |
| Inflammation, Diabetes Mellitus, Non-Insulin-Dependent, Hyperglycemia, Hyperlipidemia | Altered Intercellular Communication | Low-grade inflammation, characterized by increased pro-inflammatory cytokine levels, is present in patients with obesity-linked insulin resistance, hyperglycemia and hyperlipidemia and considered to play a leading role to progression into type 2 diabetes (T2D). | 25254631 |
| Inflammation, Diabetes Mellitus, Non-Insulin-Dependent | Altered Intercellular Communication | In adipose tissue in obese patients and in pancreatic islets in T2D patients cellular inflammation is present. | 25254631 |
| Gastroesophageal reflux disease, Inflammation, Bipolar Disorder | Altered Intercellular Communication | Studies have shown that chronic inflammation may play a vital role in the pathophysiology of both gastroesophageal reflux disease (GERD) and bipolar disorder. | 25255080 |
| ARCN1 gene, Aneurysm, Inflammation, Arterial Occlusive Diseases | Altered Intercellular Communication | Here we show that COPD is significantly more prevalent in aneurysm patients compared to arterial occlusive disease patients, independent of smoking, other clinical risk factors and inflammation. | 25255451 |
| ARCN1 gene, Inflammation, Aneurysm | Altered Intercellular Communication | Our experimental data identify genetic susceptibility to extracellular matrix degradation and secondary inflammation as the common mechanisms in both COPD and aneurysm formation. | 25255451 |
| Small cell carcinoma of lung | Altered Intercellular Communication | A systemic inflammation-based prognostic scores (mGPS) predicts overall survival of patients with small-cell lung cancer. | 25256672 |
| Inflammation, Fibrosis Assessment, Hepatitis | Altered Intercellular Communication | Biopsies were systematically reviewed for inflammation, fibrosis and the presence of interface hepatitis, plasma cells, rosettes and emperipolesis with a well-defined assessment method. | 25257662 |
| Infarction, Inflammation | Altered Intercellular Communication | Downregulation of serum brain specific microRNA is associated with inflammation and infarct volume in acute ischemic stroke. | 25257664 |
| Inflammation, Hyperreactivity, Chronic inflammatory disorder | Altered Intercellular Communication | Asthma is a highly prevalent chronic inflammatory disease characterised by reversible airflow obstruction and hyperreactivity and inflammation of the airways. | 25258133 |
| Inflammation, Parkinson Disease, Presenile dementia, Coronary heart disease, Cerebrovascular accident, Diabetes Mellitus, Depression, CTCAE, Hypertension, CTCAE | Altered Intercellular Communication | In depression patients who do not exhibit risk factors, including hypertension, diabetes, coronary heart disease, stroke, Parkinson's disease and dementia, particularly in young people, inflammation is a likely risk factor for depression. | 25258357 |
| Depression, CTCAE | Altered Intercellular Communication | Inflammatory processes, which provoke alternations of neurotransmitter metabolism, neuroendocrine function, and neuroplasticity in the brain, might promote depression. | 25258357 |
| Pain Distress Question, Inflammation, Retinal Detachment, Secondary Infections, Endophthalmitis, CTCAE, Conjunctival hemorrhage | Altered Intercellular Communication | Other adverse events, such as conjunctival hemorrhage, eye pain, secondary infection, endophthalmitis, noninfectious inflammation, retinal detachment, and implant migration, were also recorded during follow-up. | 25258512 |
| Inflammation | Altered Intercellular Communication | Topical ketorolac may reduce the inflammation caused by photocoagulation and improve visual outcome. | 25259426 |
| Inflammation, Retinal damage | Altered Intercellular Communication | It is characterized by intraocular neovascularization, inflammation and retinal damage which can be ameliorated through intraocular injections of glucocorticoids. | 25259682 |
| Inflammation, Chronic Kidney Diseases | Altered Intercellular Communication | There is evidence that chronic inflammation is associated with the progression/development of chronic renal failure; however, relations in subjects with preserved renal function remain insufficiently understood. | 25259714 |
| Inflammation, Kidney Failure | Altered Intercellular Communication | To examine the association of inflammation with the development of renal failure in a cohort of the elderly general population. | 25259714 |
| Inflammation, Overhydration | Altered Intercellular Communication | Study on overhydration in dialysis patients and its association with inflammation. | 25259812 |
| HD Term Type, Chronic Kidney Diseases | Altered Intercellular Communication | Patients with chronic kidney disease receiving haemodialysis (HD) have permanent variations in hydration status that may affect their survival. To analyse hydration status and body composition in patients on haemodialysis and its relation to inflammation. We included 128 prevalent clinically stable patients on haemodialysis. | 25259812 |
| Granulomatous inflammation, Scedosporium apiospermum | Altered Intercellular Communication | The biopsy revealed granulomatous inflammation with numerous fungal hyphae, which were IDentified as Scedosporium apiospermum by PCR. | 25260303 |
| Sepsis, Inflammation, Liver damage | Altered Intercellular Communication | Impact of plasma histones in human sepsis and their contribution to cellular injury and inflammation. | 25260379 |
| Inflammation, Liver damage, septic | Altered Intercellular Communication | Histone levels in septic patients are significantly increased and might mediate disease aggravation by cellular injury and inflammation via TLR4 signaling, which potentially results in multiple organ failure and fatal outcome. | 25260379 |
| Inflammation | Altered Intercellular Communication | Elaboration is also needed on the mechanisms by which social disadvantage may cause chronic inflammation. | 25260501 |
| Inflammation | Altered Intercellular Communication | Inflammation, including complement activation, plays an important role in tumorigenesis. | 25261356 |
| Communicable Diseases, Inflammation | Altered Intercellular Communication | IL-17A is a proinflammatory cytokine, which modulates immune cell trafficking and is involved inflammation in (auto)immune and infectious diseases. | 25261478 |
| Chronic inflammation | Altered Intercellular Communication | The MPO concentration is likely to increase in patients with chronic inflammation. | 25261597 |
| Refractory anemias, Rheumatoid Arthritis | Altered Intercellular Communication | Here, we determined serum MPO levels in rheumatoid arthritis (RA) and other autoimmune or inflammatory conditions, and investigated the associations between MPO levels and disease activity indicators in RA. | 25261597 |
| Inflammation, Stomach Carcinoma | Altered Intercellular Communication | Inflammation plays an important role in gastric cancer (GC) development and progression. | 25261987 |
| Per Visual Field, Inflammation, Vessel Failure Indicator | Altered Intercellular Communication | Inflammation plays a key role in the multi-factorial process eventually leading to target vessel failure (TVF) after drug-eluting-stent (DES) implantation. | 25262477 |
| Inflammation, Cerebral Hemorrhage | Altered Intercellular Communication | YKL-40 is associated with inflammation and severity of intracerebral hemorrhage, and may independently predict long-term clinical outcomes of intracerebral hemorrhage. | 25262987 |
| Skeletal muscle atrophy | Altered Intercellular Communication | The E3 ubiquitin ligase TRIM62 and inflammation-induced skeletal muscle atrophy. | 25263070 |
| Inflammation | Altered Intercellular Communication | Inflammation and acute-phase response occur directly within myocytes and contribute to ICUAW. | 25263070 |
| Inflammation | Altered Intercellular Communication | We observed that tripartite motif-containing 62 (TRIM62), an E3 ubiquitin ligase and modifier of inflammation, is increased in the skeletal muscle of ICUAW patients. | 25263070 |
| Inflammation | Altered Intercellular Communication | It could play a role in the pathogenesis of ICUAW by activating and maintaining inflammation in myocytes. | 25263070 |
| Diabetic Nephropathy, Inflammation, Metabolic Diseases, Fibrosis Assessment | Altered Intercellular Communication | Klotho may participate in the development of DKD pathological mechanism such as oxidative stress related to inflammation, renal fibrosis, lipid metabolic disorders, modulating the pathological process of diabetic kidney tissue. | 25263500 |
| Orchitis | Altered Intercellular Communication | It was found instead a higher diverticular inflammation degree in patients treated for DD compared with those treated for ADK associated with DD. | 25263945 |
| Inflammation, Burn injury | Altered Intercellular Communication | Serum albumin levels correlate with inflammation rather than nutrition supply in burns patients: a retrospective study. | 25264055 |
| Inflammation, Burn injury | Altered Intercellular Communication | To clarify whether provision of nutrition or presence of inflammation affects serum albumin levels, we studied serum albumin levels, C-reactive protein (CRP) levels and caloric intake over time in 30 patients with burns. | 25264055 |
| Inflammation | Altered Intercellular Communication | Increased permeability and uptake of proinflammatory bacterial endotoxins from gut microbiota has been suggested as a mechanism for obesity-associated chronic inflammation that causes obesity-associated insulin resistance. | 25264329 |
| Inflammation | Altered Intercellular Communication | We hypothesized that intestinal barrier function may be restored after Roux-en-Y gastric bypass (RYGB) surgery and thereby contribute to decreased inflammation. | 25264329 |
| Inflammation, Toxic effect | Altered Intercellular Communication | No significant difference was reached in toxicity, inflammation, and oxidative stress markers. | 25265206 |
| Inflammation | Altered Intercellular Communication | It triggers systemic inflammation, the role of which remains unclear. | 25265569 |
| Sepsis, Inflammation | Altered Intercellular Communication | In the current study, we investigated the induction of microRNA (miRNA) during sepsis and their role in the regulation of inflammation. | 25265569 |
| Sepsis, Inflammation | Altered Intercellular Communication | The current study demonstrates that miRNA dysregulation correlates with clinical manifestations and inflammation, and therefore remains a potential therapeutic target against sepsis. | 25265569 |
| Inflammation, Sarcoidosis | Altered Intercellular Communication | Microscopically, cutaneous sarcoidosis may exhibit a grenz zone and may show perineural inflammation and foreign bodies. | 25265873 |
| Inflammation, Primary malignant neoplasm | Altered Intercellular Communication | Chemokines and their receptors acts as mediators of migration of immune cells to the site of inflammation and deregulated inflammatory response is associated with increased risk of cancer. | 25266801 |
| Inflammation, Hypertensive (finding), Hypertension, CTCAE | Altered Intercellular Communication | Associations of daytime, nighttime, and 24-hour heart rate with four distinct markers of inflammation in hypertensive patients: the Styrian Hypertension Study. | 25266946 |
| Inflammatory Bowel Diseases, Inflammation | Altered Intercellular Communication | The transcription factor NF-kB is indispensable for intestinal immune homeostasis, but contributes to chronic inflammation and inflammatory bowel disease (IBD). | 25267258 |
| Esophagitis | Altered Intercellular Communication | The median CReSS total in volunteers (4) was significantly lower (P < .002) than in ear, nose, and throat (ENT) patients (26) or EGD patients with (42) or without (32) esophageal inflammation. | 25267601 |
| Acute inflammation | Altered Intercellular Communication | All corneas were clear and only mild postoperative inflammation was observed. | 25268083 |
| ARCN1 gene, Inflammation, Asthma | Altered Intercellular Communication | These findings suggest that IL-35 may very probably be involved in the Th2 and Th17 mediated inflammation process of asthma and COPD. | 25268338 |
| Airway structure, Asthma | Altered Intercellular Communication | The most important way to achieve and maintain asthma control is to reduce airway inflammation. | 25268339 |
| Communicable Diseases, Inflammation, Neoplasms | Altered Intercellular Communication | Thus, the assessment of the HCMV expression in tumours of various origins and pathologically altered tissue in conditions such as inflammation, infection, and even degeneration should certainly be facilitated. | 25268364 |
| Inflammation, Coronary Artery Disease | Altered Intercellular Communication | Elevations in soluble markers of inflammation and changes in leukocyte subset distribution are frequently reported in patients with coronary artery disease (CAD). | 25268632 |
| Infection caused by Helicobacter pylori | Altered Intercellular Communication | It was shown that GM inflammation in patients with DU and BA is associated not only with H. pylori infection but also with the phase of BA. | 25269182 |
| Inflammation | Altered Intercellular Communication | Growing density of eosinophil, neutrophil and mast cell infiltration of fundal and antral GM as well as increased total number of cells in the antrum reflects active immune-mediated inflammation in GM lamina propria. | 25269182 |
| Inflammation | Altered Intercellular Communication | One of the possible factors determining combination of H. pylori-associated duodenal ulcer with BA is chronic hyperergic inflammation and marked structural changes in GM. | 25269182 |
| Granulomatous inflammation, Sarcoidosis | Altered Intercellular Communication | In sarcoidosis, an antigen specific immune response is a putative mechanism, resulting in granulomatous inflammation. | 25269709 |
| Airway structure | Altered Intercellular Communication | It increases airway inflammation and influences outcomes negatively. | 25269711 |
| Refractory anemias, Inflammation, destruction joint, Rheumatoid Arthritis | Altered Intercellular Communication | Synovial inflammation and joint destruction in rheumatoid arthritis (RA) may progress despite clinical remission. | 25270553 |
| Refractory anemias, Inflammation | Altered Intercellular Communication | Dynamic contrast-enhanced magnetic resonance imaging (DCE-MRI) is increasingly used to detect synovial inflammation in RA. | 25270553 |
| Inflammation | Altered Intercellular Communication | Perfusion imaging of synovial tissue in RA finger joints employing DCE-MRI reflects histological synovial inflammation. | 25270553 |
| Carcinoma, Chronic osteomyelitis | Altered Intercellular Communication | Inflammation- and tumor-free alveolar bone sections from human mandibles (n = 31) with previously diagnosed carcinoma, chronic osteomyelitis or cysts were analyzed histomorphologically and histomorphometrically as to the dimension of trabeculae in cancellous areas. | 25271067 |
| Liver carcinoma | Altered Intercellular Communication | Systemic immune-inflammation index predicts prognosis of patients after curative resection for hepatocellular carcinoma. | 25271081 |
| Liver carcinoma, FAM126A gene | Altered Intercellular Communication | We developed a novel systemic immune-inflammation index (SII) based on lymphocyte, neutrophil, and platelet counts and explored its prognostic value in hepatocellular carcinoma (HCC). | 25271081 |
| Inflammation, Chronic frontal sinusitis, Frontal Sinusitis | Altered Intercellular Communication | The goal of this study was to identify these anatomical factors and inflammation areas relating to chronic frontal sinusitis by comparing radiological presentations in patients with and without frontal sinusitis. | 25271525 |
| Chronic frontal sinusitis, Inflammatory disease of mucous membrane | Altered Intercellular Communication | It provides evidence that mucosal inflammation disease in these two areas is a very important factor leading to chronic frontal sinusitis. | 25271525 |
| Inflammation, Traumatic injury | Altered Intercellular Communication | The molecular dynamics governing immune cell recruitment to sites of injury and disease in the CNS during sterile inflammation remain poorly defined. | 25271625 |
| Inflammation, Contracture, Microbial Biofilms | Altered Intercellular Communication | The etiology is uncertain, but bacterial biofilms have been suggested as trigger for chronic peri-implant inflammation, eventually leading to capsular contracture. | 25272211 |
| Inflammation, Injury of cardiac valve | Altered Intercellular Communication | We hypothesize that biomarkers for inflammation, neurohumoral activation, and cardiac injury can predict appropriate shocks and all-cause mortality in patients with primary prevention ICDs. | 25273351 |
| Cessation of life, Inflammation, Shock, myocardial injury | Altered Intercellular Communication | An increase in serum biomarkers of inflammation, neurohumoral activation, and myocardial injury increased the risk for death but poorly predicted the likelihood of an ICD shock. | 25273351 |
| Inflammation, Carotidynia | Altered Intercellular Communication | Carotidynia is characterised by inflammation limited to the common carotid artery, which has been recognised as a distinct disease entity by advanced vascular imaging. | 25273942 |
| Inflammation | Altered Intercellular Communication | We report a ventriculo-atrial defect due to a paravalvular aortic prosthetic defect, secondary to inflammation, a novel third type of a Gerbode defect. | 25274005 |
| Inflammation, Fibrosis Assessment | Altered Intercellular Communication | YKL-40 is a novel biomarker in diseases with inflammation, fibrosis and tissue remodelling. | 25274153 |
| Inflammation, Smoking | Altered Intercellular Communication | Smoking is associated with a broad range of alterations in systemic immune and inflammation marker levels among older, long-term smokers. | 25274579 |
| Refractory anemias, Rheumatoid Arthritis, Arthritis | Altered Intercellular Communication | To determine whether macrophage targeting by (R)-11C-PK11195 positron emission tomography (PET) can visualize subclinical joint inflammation in patients with rheumatoid arthritis (RA) without clinical arthritis during or after treatment, with flare as clinical outcome measure. | 25274888 |
| Rheumatoid Arthritis | Altered Intercellular Communication | Patients with rheumatoid arthritis in clinical remission manifest persistent joint inflammation on histology and imaging studies. | 25274900 |
| Refractory anemias, Rheumatoid Arthritis, Inflammation, Synovitis | Altered Intercellular Communication | The purpose of our study was to test the hypothesis that synovitis on magnetic resonance imaging (MRI) and ultrasound (US) observed in patients with rheumatoid arthritis (RA) who meet remission criteria reflects active inflammation on histopathology. | 25274900 |
| Inflammation, Hyperplasia | Altered Intercellular Communication | Histological specimens were scored for hyperplasia of synovial lining and synovial stroma, inflammation, lymphoid follicles, and vascularity. | 25274900 |
| Stomach Carcinoma | Altered Intercellular Communication | Improvement of high-sensitivity inflammation-based Glasgow prognostic score by gastrectomy is a favorable prognostic factor in patients with gastric cancer. | 25275076 |
| Bronchitis | Altered Intercellular Communication | However, little is known about the role of prostacyclin in neutrophilic bronchial inflammation. | 25275218 |
| Carcinoma of lung | Altered Intercellular Communication | Prognostic significance of systemic inflammation-based lymphocyte- monocyte ratio in patients with lung cancer: based on a large cohort study. | 25275631 |
| Inflammation | Altered Intercellular Communication | The relatively benign-appearing radiograph and biopsy report of chronic inflammation resulted in curettage and nailing of the lesion. | 25275985 |
| Inflammation, Sleep Apnea, Obstructive | Altered Intercellular Communication | Inflammation and growth in young children with obstructive sleep apnea syndrome before and after adenotonsillectomy. | 25276051 |
| Inflammation | Altered Intercellular Communication | Our findings imply that systemic inflammation may have an important role in this OSA-related morbidity. | 25276051 |
| Inflammation, Chronic disease | Altered Intercellular Communication | The 0.5% Jussara supplementation reverses the adverse effects of perinatal TFAs, improving lipid profiles, glucose levels, body composition, and gut microbiota and reducing low-grade inflammation in the colon of 21-day-old offspring, and could contribute to reducing chronic disease development. | 25276060 |
| Alzheimers Disease", Inflammation | Altered Intercellular Communication | In Alzheimer's disease, the contribution of inflammation is still controversially discussed. | 25277040 |
| Primary malignant neoplasm, Depression, CTCAE | Altered Intercellular Communication | Cancer patients under maintenance hemodialysis: relationship between quality of life, depression, sleep quality and malnutrition-inflammation score. | 25277248 |
| methyldopa, Polypoidal choroidal vasculopathy | Altered Intercellular Communication | To determine the genetic association of an inflammation-related gene, formyl peptide receptor 1 (FPR1), in exudative age-related macular degeneration (AMD) and polypoidal choroidal vasculopathy (PCV). | 25277308 |
| Inflammation, Hypercholesterolemia | Altered Intercellular Communication | Nonpharmacological lipoprotein apheresis reduces arterial inflammation in familial hypercholesterolemia. | 25277610 |
| Arteritis | Altered Intercellular Communication | There was a significant reduction of arterial inflammation after lipoprotein apheresis (TBR: 2.05 +- 0.31 vs. 1.91 +- 0.33; p < 0.02). | 25277610 |
| Inflammation, Family history | Altered Intercellular Communication | The arterial wall of FH patients is characterized by increased inflammation, which is markedly reduced after lipoprotein apheresis. | 25277610 |
| Inflammation, Atrial Fibrillation by ECG Finding | Altered Intercellular Communication | Fish oil for the reduction of atrial fibrillation recurrence, inflammation, and oxidative stress. | 25277614 |
| Inflammation | Altered Intercellular Communication | Furthermore, fish oil does not reduce inflammation or oxidative stress markers in this population, which may explain its lack of efficacy. | 25277614 |
| Inflammation, Demyelination, MS gene, Nerve Degeneration | Altered Intercellular Communication | Oxidative stress induced by lipid peroxidation is related with inflammation of demyelination and neurodegeneration in multiple sclerosis. | 25277682 |
| Inflammation | Altered Intercellular Communication | Inflammation can lead to oxidative stress and vice versa. | 25277682 |
| Inflammation, Demyelination, MS gene, Nerve Degeneration | Altered Intercellular Communication | Thus, oxidative stress is involved in the inflammation leading demyelination and neurodegeneration in the pathogenesis of multiple sclerosis. | 25277682 |
| Inflammation | Altered Intercellular Communication | All underwent abdominal CT which showed ovoid fat inflammation along the course of the perigastric ligaments (gastrohepatic, gastrosplenic, and falciform). | 25278036 |
| Inflammation | Altered Intercellular Communication | Although the inflammation was correctly described, the specific diagnosis was not made on initial interpretation in five patients. | 25278036 |
| Inflammation | Altered Intercellular Communication | Radiologists should be aware of the entity to avoid unnecessary intervention, and recognize the CT findings of ovoid fat inflammation in the distribution of the perigastric ligaments. | 25278036 |
| Inflammation | Altered Intercellular Communication | Dynamic, contrast-enhanced magnetic resonance imaging (DCE MRI) provides quantitative, novel measures of synovial inflammation. | 25278070 |
| Inflammation | Altered Intercellular Communication | The association between EER and symptomatic response to IACS may reflect a closer relation of this biomarker to synovial inflammation than with volumetric assessment. | 25278070 |
| Degenerative polyarthritis, Inflammation | Altered Intercellular Communication | The degree to which these features reflect "active inflammation" is questionable and they may be better considered as part of the total organ pathology in OA. | 25278071 |
| Degenerative polyarthritis, Inflammation | Altered Intercellular Communication | Imaging of (peri)articular structures and inflammation with Ultrasonography (US) during the course of osteoarthritis (OA) might contribute to knowledge about early diagnosis of OA, prognosis and possibly the effect of disease modifying drugs. | 25278074 |
| Synovial Hypertrophy | Altered Intercellular Communication | Inflammation like effusion and synovial hypertrophy does occur in over 40% of patients at some time in the year of follow up and shows a fluctuating pattern. | 25278074 |
| Degenerative polyarthritis, Inflammation | Altered Intercellular Communication | MUS examination for knee OA consists of five separate domains assessing (1) predominantly morphological changes in the medial compartment, (2) predominantly inflammation in the medial compartment, (3) predominantly morphological changes in the lateral compartment, (4) predominantly inflammation in the lateral compartment, and (5) effusion. | 25278077 |
| Alopecia Areata, Dacryoadenitis | Altered Intercellular Communication | The association of lacrimal gland inflammation with alopecia areata. | 25280049 |
| Alopecia Areata, Dacryoadenitis | Altered Intercellular Communication | To describe the association of lacrimal gland inflammation with alopecia areata. | 25280049 |
| Alopecia, CTCAE, Dacryoadenitis | Altered Intercellular Communication | We reviewed the medical records of 4 patients diagnosed with lacrimal gland inflammation who had an antecedent or subsequent episode of alopecia. | 25280049 |
| Alopecia, CTCAE, LACRIMAL INFLAMMATION | Altered Intercellular Communication | Two developed alopecia after presentation for lacrimal inflammation. | 25280049 |
| Alopecia Areata, Dacryoadenitis | Altered Intercellular Communication | Lacrimal gland inflammation and alopecia areata are autoimmune processes that can be seen in association with each other. | 25280049 |
| Hypoparathyroidism, Primary Hypoparathyroidism, Hypocalcemia | Altered Intercellular Communication | Primary hypoparathyroidism is a rare condition caused by parathyroid hormone deficiency and characterized by hypocalcemia. | 25280468 |
| Abnormal renal function, Inflammation | Altered Intercellular Communication | In the United States population, high dietary fiber intake has been associated with a lower risk of inflammation and mortality in individuals with kidney dysfunction. | 25280496 |
| Communicable Diseases, Inflammation, Aspergillus fumigatus allergenic extract | Altered Intercellular Communication | Trans-sphenoidal surgery with biopsy showed inflammation was caused by infection with Aspergillus fumigatus. | 25280605 |
| Inflammation, Observation Method - Coagulation, Viremia | Altered Intercellular Communication | Activation, senescence, exhaustion and differentiation stage in CD4+ and CD8+ T lymphocyte subsets, markers of monocyte activation, microbial translocation, inflammation, coagulation and low-level viremia were assessed. | 25280865 |
| Inflammation | Altered Intercellular Communication | Monocyte activation was independently associated with markers of inflammation (IL-6, p=0.006), microbial translocation (LBP, p=0.01) and low-level viremia (p=0.01). | 25280865 |
| Neurodegenerative Disorders, Abnormality of mitochondrial metabolism, Disturbance | Altered Intercellular Communication | Thus, neurosteroids may act upon neuronal bioenergetics in a delicate balance and an age-related steroid disturbance might be involved in mitochondrial dysfunction underlying neurodegenerative disorders. | 25281013 |
| Airway structure, Asthma | Altered Intercellular Communication | Few data are available on the proportion of asthmatics achieving a good asthma control (according GINA guidelines) and on the level of airway inflammation during omalizumab treatment. | 25281265 |
| Aggressive course, Malignant neoplasm of endometrium | Altered Intercellular Communication | In endometrial cancer loss of progesterone receptor (PR, gene name PGR) is associated with aggressive disease and altered response to hormonal treatment. | 25281525 |
| Inflammation | Altered Intercellular Communication | Compare the efficacy of inhaled budesonide and systemic methylprednisolone on systemic inflammation of AECOPD. | 25281894 |
| Inflammation | Altered Intercellular Communication | To compare the efficacy of inhaled budesonide and systemic methylprednisolone on systemic inflammation of AECOPD. | 25281894 |
| Inflammation | Altered Intercellular Communication | Inhaled budesonide and systemic methylprednisolone have the same effects on systemic inflammation of AECOPD. | 25281894 |
| Inflammation, atherosclerotic, Atherosclerosis | Altered Intercellular Communication | We demonstrated that sRAGE and esRAGE are associated with atherosclerotic risk factors in early-stage atherosclerosis, suggesting that their levels evolve in correlation with those of metabolic components and inflammation. | 25282185 |
| Refractory anemias, Inflammation | Altered Intercellular Communication | The S100A12 protein was significantly associated with other inflammatory markers, clinical assessments as well as sum US scores, indicating that S100A12 is a potential marker of inflammation in RA patients. | 25282581 |
| Inflammation, Fibrosis Assessment | Altered Intercellular Communication | Galectin-3 has been recently recognized as a biomarker of cardiovascular fibrosis and inflammation. | 25282685 |
| Inflammation | Altered Intercellular Communication | [Odontogenic inflammations of head and neck area treated in the Department of Otolaryngology in St. Lukasz Regional Hospital - five years observation]. | 25283320 |
| Inflammation | Altered Intercellular Communication | That's why treatment of odontogenic inflammations is often difficult and prolonged. | 25283320 |
| Inflammation | Altered Intercellular Communication | The authors reveal a cost burden in a public health care as a result of odontogenic inflammations. | 25283320 |
| Inflammation, Swelling | Altered Intercellular Communication | Three patients with remote filler injection (hyaluronic acid and polyalkylimide), not volunteered on initial history, presented with peri-orbital swelling and/or inflammation that was suspicious in each case for more serious pathology. | 25284105 |
| Inflammation, Sarcoidosis, Psoriasis, Chronic inflammatory disorder | Altered Intercellular Communication | Like psoriasis, sarcoidosis is a chronic inflammatory disorder with Th1/Th17-driven inflammation. | 25285443 |
| Inflammation, "Alzheimers Disease", Data types - Address | Altered Intercellular Communication | Chronic inflammation is a key feature of the pathology present in Alzheimer's disease (AD)-affected brains resulting from responses to amyloid plaques or neurofibrillary tangles, the pathological hallmarks of AD. | 25286386 |
| Hypernatremia, Inflammation, Fibrosis Assessment, Heart Ventricle | Altered Intercellular Communication | Sex-dependent regulation of fibrosis and inflammation in human left ventricular remodelling under pressure overload. | 25287281 |
| Adenocarcinoma, Inflammation, Specimen Source Codes - Abscess | Altered Intercellular Communication | The pathologic report showed severe inflammation with abscess formation and an unexpected adenocarcinoma that appeared to invade the perimuscular connective tissue. | 25287623 |
| Inflammation, Macular degeneration | Altered Intercellular Communication | The significant associations of mCNV in highly myopic eyes with elevated levels of vascular endothelial growth factor or inflammatory cytokines and maculopathy lesions strongly suggest an involvement of inflammation in the etiology of mCNVs. | 25289657 |
| Inflammation, Non-Small Cell Lung Carcinoma, pulmonary toxicity | Altered Intercellular Communication | Lung inflammation leading to pulmonary toxicity after radiotherapy (RT) can occur in patients with non-small cell lung cancer (NSCLC). | 25289758 |
| Toxic effect, Gastrointestinal inflammation, Leukopenia, Maculopapular Lesion, DLST wt Allele | Altered Intercellular Communication | Dose-limiting toxicities (DLTs) for dalotuzumab/MK-2206 included grade 4 neutropenia and grade 3 serum sickness-like reaction, maculopapular rash, and gastrointestinal inflammation. | 25290091 |
| Sepsis, Thrombosis of jugular vein, septic | Altered Intercellular Communication | Septic internal jugular vein thrombosis should always be included in the differential diagnosis of local neck inflammation and systemic sepsis in intravenous drug users. | 25290582 |
| Malignant tumor of colon, Inflammation, Inflammatory Bowel Diseases, Colitis, Primary sclerosing cholangitis, Colorectal Carcinoma | Altered Intercellular Communication | Colon cancer risk in IBD increases with longer duration and greater anatomic extent of colitis, the presence of primary sclerosing cholangitis, family history of CRC and degree of inflammation of the bowel. | 25292045 |
| Inflammation, Malignant Neoplasms | Altered Intercellular Communication | Interleukin-12 (IL-12) as an antitumor and interleukin-6 (IL-6) as an inflammatory cytokine, are immunomodulatory products that play important roles in responses in cancers and inflammation. | 25292079 |
| Stomach Carcinoma | Altered Intercellular Communication | Prognostic value of preoperative inflammation-based prognostic scores on hospital mortality after gastric cancer surgery. | 25292085 |
| Inflammation, Stomach Carcinoma | Altered Intercellular Communication | Previous studies demonstrated relationships between gastric cancer and chronic inflammation. | 25292085 |
| Venous Thromboembolism, Cerebrovascular accident | Altered Intercellular Communication | Inflammation markers and incident venous thromboembolism: the REasons for Geographic And Racial Differences in Stroke (REGARDS) cohort. | 25292154 |
| Inflammation, Venous Thromboembolism, vinyltriethoxysilane, Obesity | Altered Intercellular Communication | Inflammation biomarkers are associated with the venous thromboembolism (VTE) risk factors obesity and age; however, the relationships of inflammation with VTE risk remain controversial. | 25292154 |
| Inflammation, vinyltriethoxysilane, Obesity | Altered Intercellular Communication | These data suggest that inflammation may be a potential mechanism underlying the relationship between obesity and VTE risk. | 25292154 |
| Non-alcoholic Fatty Liver Disease, Impaired health | Altered Intercellular Communication | This impairment may affect HSP70-dependent anti-inflammation, with consequent oxidative stress and insulin resistance in advanced stages of NAFLD. | 25292174 |
| Prostate carcinoma, Benign prostatic hypertrophy, prostatitis | Altered Intercellular Communication | Prostatic inflammation is of considerable importance to urologic research because of its association with benign prostatic hyperplasia and prostate cancer. | 25292180 |
| Inflammation | Altered Intercellular Communication | However, the mechanisms by which inflammation leads to proliferation and growth remain obscure. | 25292180 |
| Inflammation, Hyperplasia | Altered Intercellular Communication | Using genetic models and in vivo IGF receptor blockade, we demonstrate that the hyperplastic response to inflammation depends on interleukin-1-driven IGF signaling. | 25292180 |
| Inflammation, Benign prostatic hypertrophy | Altered Intercellular Communication | We show that human prostatic hyperplasia is associated with IGF pathway activation specifically localized to foci of inflammation. | 25292180 |
| Hyperplasia | Altered Intercellular Communication | This demonstrates that mechanisms of inflammation-induced epithelial proliferation and hyperplasia involve the induction of developmental growth factors, further establishing a link between inflammatory and developmental signals and providing a mechanistic basis for the management of proliferative diseases by IGF pathway modulation. | 25292180 |
| Refractory anemias, Inflammation, Damage | Altered Intercellular Communication | Combination of HR-pQCT and MRI modalities may provide powerful tools to evaluate joint inflammation and bone damage in RA. | 25293500 |
| Candida albicans, Inflammation, Dental Plaque | Altered Intercellular Communication | In addition, those who wore dentures during sleep were more likely to have tongue and denture plaque, gum inflammation, positive culture for Candida albicans, and higher levels of circulating interleukin-6 as compared with their counterparts. | 25294364 |
| Primary malignant neoplasm, Liver carcinoma, FAM126A gene | Altered Intercellular Communication | Hepatocellular carcinoma (HCC) is a prototype of inflammation-associated cancer. | 25294684 |
| Hepatocarcinogenesis | Altered Intercellular Communication | The finding of IL-1b/IRAK-1 signaling promoting Gankyrin expression through JNK and NF-Y/p300/CBP complex provides a fresh view on inflammation-enhanced hepatocarcinogenesis. | 25294684 |
| Hepatocarcinogenesis | Altered Intercellular Communication | Interleukin-1b/Iinterleukin-1 receptor-associated kinase 1 inflammatory signaling contributes to persistent Gankyrin activation during hepatocarcinogenesis. | 25294684 |
| Inflammation, Diabetes Mellitus | Altered Intercellular Communication | DPP4 activity is an important predictor of the onset of inflammation and MAU in Chinese apparently without diabetes. | 25294850 |
| ovarian neoplasm, Pelvic Inflammatory Disease, Endometriosis | Altered Intercellular Communication | We performed here a comprehensive immune gene expression analysis of pelvic inflammation in endometriosis and endometriosis-associated ovarian cancer (EAOC). | 25294912 |
| Inflammation, Endometriosis | Altered Intercellular Communication | One third of the patients with endometriosis revealed a tumor-like inflammation profile, suggesting that cancer-like immune signatures may develop earlier, in patients classified as clinically benign. | 25294912 |
| Inflammation, Endometriosis | Altered Intercellular Communication | These findings reveal new characteristics of inflammation in precursor lesions and point to previously unknown roles of complement in endometriosis and EAOC. | 25294912 |
| Inflammatory, Inflammation | Altered Intercellular Communication | Angiopoietin-like protein 2 (ANGPTL2) is a mediator of chronic inflammation and inflammatory carcinogenesis. | 25294915 |
| Inflammation, Cyclophosphamide/Vincristine/Dacarbazine Regimen, Cardiovascular Diseases | Altered Intercellular Communication | Leptin, a possible mediator between energy homeostasis, inflammation and cardiovascular disease (CVD), acts via leptin receptors. | 25296580 |
| Endocrine System Diseases, Acne, Inflammatory acne | Altered Intercellular Communication | The stereotype of adult female acne being due to hormonal disturbances presenting as inflammatory acne localized only to the mandibular area was not found in the majority of this large group. | 25296739 |
| Inflammation, Schistosoma, Colonic Polyps | Altered Intercellular Communication | However, colon polyps associated with Schistosoma in the absence of inflammation have rarely been reported, especially in young people; this is the first case with the following presentation. | 25296942 |
| Giant Cell Arteritis, Granulomatous inflammation, GCA gene, Autoimmune Diseases | Altered Intercellular Communication | Giant cell arteritis (GCA) is an autoimmune disease characterized by granulomatous inflammation in the wall of medium-sized and large-sized arteries, and it usually occurs in patients over 50 years of age. | 25297504 |
| Inflammation, Bacterial Endocarditis | Altered Intercellular Communication | Inflammation in infective endocarditis (IE) is a complex network including interactions of inflammatory cytokines and other components of host response. | 25299518 |
| Inflammation, Alpha one fetoprotein measurement, Myelitis, Acute flaccid paralysis | Altered Intercellular Communication | In August 2012, the California Department of Public Health (CDPH) was contacted by a San Francisco Bay area clinician who requested poliovirus testing for an unvaccinated man aged 29 years with acute flaccid paralysis (AFP) associated with anterior myelitis (i.e., evidence of inflammation of the spinal cord involving the grey matter including anterior horn cell bodies) and no history of international travel during the month before symptom onset. | 25299608 |
| Inflammation, Obesity | Altered Intercellular Communication | Human SC WAT increases thermogenic genes seasonally and acutely in response to a cold stimulus and this response is inhibited by obesity and inflammation. | 25299843 |
| Inflammation, atherosclerotic | Altered Intercellular Communication | Measurement of high sensitivity CRP (hsCRP) and lipoprotein-associated phospholipase A2 (LpPLA2) provides information on systemic inflammation and stability of atherosclerotic plaques. | 25300684 |
| ARCN1 gene, Airway structure | Altered Intercellular Communication | Extracellular ATP is increased in the COPD affected lung and may play a key role in driving CS-induced airway inflammation, but the mechanism involved in ATP release has eluded researchers. | 25301060 |
| Airway structure | Altered Intercellular Communication | Mice were exposed to mainstream CS and airway inflammation assessed. | 25301060 |
| ARCN1 gene, Inflammation | Altered Intercellular Communication | This suggests a role of systemic inflammation in the early induction phase of COPD. | 25301367 |
| Inflammation, Carcinogenesis | Altered Intercellular Communication | S100/calgranulins (S100A8, S100A9 and S100A12) are key players of innate immune function and elevated levels are a characteristic feature of acute and chronic inflammation, and inflammation-associated carcinogenesis. | 25302747 |
| Inflammation, Fibrosis Assessment | Altered Intercellular Communication | We observed a significant association of rs58542926 and disease severity (P = 0.027), but not lobular inflammation or fibrosis; rs58542926 was not associated with levels of liver enzymes. | 25302781 |
| Cataract | Altered Intercellular Communication | Discrepant expression of cytokines in inflammation- and age-related cataract patients. | 25303043 |
| Refractory anemias, Rheumatoid Arthritis | Altered Intercellular Communication | Studies suggest that hormonal states affect disease characteristics in women with rheumatoid arthritis (RA). | 25303739 |
| Inflammation, Chronic Obstructive Airway Disease | Altered Intercellular Communication | Pentraxin 3 as a novel biomarker of inflammation in chronic obstructive pulmonary disease. | 25303877 |
| Inflammation, Ocular Hypotension, Hyphema | Altered Intercellular Communication | Two subjects developed mild transient hyphema, and none exhibited prolonged inflammation, persistent hypotony, or hypotony maculopathy. | 25304276 |
| Inflammation, Brain Injuries | Altered Intercellular Communication | Because inflammation is a strong mediator of secondary brain injury, a blunted proinflammatory response after rewarming may be beneficial. | 25304549 |
| Inferior vena cava structure, Inflammation | Altered Intercellular Communication | Early onset of periaortic inflammation after EVAR with inferior vena cava involvement: a case report. | 25304907 |
| Inflammation | Altered Intercellular Communication | Instead, the onset of periaortic inflammation after EVAR is a rare event with an unclear pathogenesis, time of onset, and clinical presentation. | 25304907 |
| Inflammation, Primary malignant neoplasm | Altered Intercellular Communication | To investigate whether polymorphisms of genes related to inflammation are associated with pathologic response (primary endpoint) in patients with rectal cancer treated with primary chemoradiation therapy (PCRT). | 25304949 |
| Rectal Carcinoma | Altered Intercellular Communication | If confirmed, an inflammation-related radiogenetic profile might be used to select patients with rectal cancer for preoperative combined-modality treatment. | 25304949 |
| Inflammation, Chronic disease, Cardiovascular Diseases | Altered Intercellular Communication | Inflammation plays an important role in the cause of cardiovascular diseases and may contribute to the association linking an unhealthy diet to chronic age-related diseases. | 25305231 |
| Inflammation | Altered Intercellular Communication | These data suggest that maintaining and improving adherence to healthy dietary recommendations may reduce the risk of long-term inflammation. | 25305231 |
| Gastrointestinal inflammation | Altered Intercellular Communication | Central to the study is the hypothesis that enteropathogen infection contributes to undernutrition by causing intestinal inflammation and/or by altering intestinal barrier and absorptive function. | 25305287 |
| Inflammation, Bacterial Infections | Altered Intercellular Communication | The role of bacterial infection in stone formation is unclear but may include alteration of urinary components, acting as a nidus for crystallization, or inducing inflammation. | 25306481 |
| Airway structure, Asthma, Exacerbation | Altered Intercellular Communication | Persistent eosinophilic airway inflammation in asthma increases the risk of exacerbations. | 25306557 |
| ARCN1 gene, Inflammation | Altered Intercellular Communication | The results concerning IL-4 and IL-6 levels can be indicative of an attempt to control inflammation after the 6MWT in COPD patients. | 25306916 |
| Inflammation | Altered Intercellular Communication | Chronic transmural inflammation and mucosal regeneration probably facilitated epithelial misplacement, which secondarily developed cytologic atypia. | 25307411 |
| Inflammation, GDC AJCC Clinical Stage Terminology | Altered Intercellular Communication | Early administration of high-dose statin therapy in patients with ACS appears to improve biomarkers of inflammation within 8 h, which may translate into fewer ischemic events. | 25307674 |
| Sleeplessness, Inflammation, Depression, CTCAE, Anxiety, CTCAE 3.0 | Altered Intercellular Communication | Sleep duration, insomnia, and markers of systemic inflammation: results from the Netherlands Study of Depression and Anxiety (NESDA). | 25307717 |
| Inflammation, Anxiety Disorders, Bipolar Disorder | Altered Intercellular Communication | Systemic inflammation has emerged as a potential pathway linking depressive and anxiety disorders with disease risk. | 25307717 |
| Sleeplessness, Inflammation, Psychiatric | Altered Intercellular Communication | Short and long sleep duration, as well as insomnia, are common among psychiatric populations and have previously been related to increased inflammation. | 25307717 |
| Sleeplessness, Inflammation | Altered Intercellular Communication | There were no clear associations between insomnia symptoms and levels of inflammation. | 25307717 |
| Inflammation, Psychiatric | Altered Intercellular Communication | Relationships between sleep duration and inflammation did not vary as a function of psychiatric diagnostic status. | 25307717 |
| Inflammation, Anxiety Disorders, Bipolar Disorder | Altered Intercellular Communication | These findings suggest that elevated levels of systemic inflammation may represent a mechanism linking long sleep duration and disease risk among those with and without depressive and anxiety disorders. | 25307717 |
| Anxiety, CTCAE 3.0, Inflammation, Bipolar Disorder, Atherosclerosis | Altered Intercellular Communication | Depressive symptoms and anxiety are predictive of prognosis, and have been associated with markers of inflammation that play a role in atherosclerosis. | 25307791 |
| Inflammation | Altered Intercellular Communication | The location of mast cells in different areas, their association with lymphocytes, fibroblasts, endothelial cells, and the phenomenon of degranulation helps to appreciate the release of various mediators and multiple interactions among these cells, leading to increased vascular permeability, angiogenic response, collagen synthesis, regulation of inflammation, bone resorption, and extracellular matrix destruction, thus contributing to the pathogenesis of these inflammatory lesions. | 25307810 |
| Hepatitis, Toxic effect | Altered Intercellular Communication | Gene-modified T cells survived, expanded and mediated a reduction in HBsAg levels without exacerbation of liver inflammation or other toxicity. | 25308176 |
| Airway structure, ARCN1 gene | Altered Intercellular Communication | We previously showed that low-dose azithromycin reduced airways inflammation in COPD subjects and we hypothesized that it would also reduce granzyme B production by CD8 T cells. | 25308201 |
| ARCN1 gene, Inflammation | Altered Intercellular Communication | We provide further evidence for the application of low-dose azithromycin as an attractive adjunct treatment option for controlling epithelial cell apoptosis, abnormal airway repair and chronic inflammation in COPD. | 25308201 |
| Inflammation, Cyclophosphamide/Vincristine/Dacarbazine Regimen, Cardiovascular Diseases | Altered Intercellular Communication | Chronic inflammation has been postulated to be one mediating mechanism explaining the association between low socioeconomic position (SEP) and cardiovascular disease (CVD). | 25309988 |
| Gastrointestinal inflammation, Ulcerative Colitis | Altered Intercellular Communication | Ulcerative colitis (UC) is characterized by increased epithelial cell death and subsequent breakdown of the intestinal epithelial barrier, which perpetuates chronic intestinal inflammation. | 25310532 |
| Inflammation, Leukocytosis | Altered Intercellular Communication | In one of these cases, the patient presented with chronic intermittent polyarthritis, systemic inflammation, and leukocytosis. | 25311252 |
| Inflammation, Skeletal muscle structure | Altered Intercellular Communication | The influence of systemic inflammation on skeletal muscle in physically active elderly women. | 25311555 |
| Glaucoma, CTCAE, Conjunctivitis | Altered Intercellular Communication | Chronic conjunctival inflammation, caused by various reasons, for example long-term use of topical drugs and/or their preservatives, affects the outcome of glaucoma surgery by interfering with wound healing. | 25312247 |
| Inflammation, Mycobacterium Infections | Altered Intercellular Communication | To obtain a more definitive diagnosis, the patient underwent a CT-guided biopsy, which showed caseating granulomatous inflammation strongly suggestive of Mycobacterium infection. | 25312889 |
| melanoma, Inflammation | Altered Intercellular Communication | Melanoma BM showed considerable lymphocytic infiltrates and expression of PD-L1 in the majority of investigated specimens, with high PD-L1 expression found predominantly in regions of abundant inflammation. | 25314639 |
| Inflammation, Sacroiliac joint structure | Altered Intercellular Communication | Erythrocyte sedimentation rate (ESR) and C-reactive protein (CRP) were elevated (35 mm/h and 9.4, respectively) and Mennel's sign was present on both sides, indicating possible inflammation of the sacroiliac joints. | 25315123 |
| ARCN1 gene, Inflammation, Chronic Obstructive Airway Disease | Altered Intercellular Communication | Immune cells expressing the activation markers HLA-DR and regulatory T cells (Tregs) may be involved in the regulation of chronic inflammation in chronic obstructive pulmonary disease (COPD). | 25315616 |
| Intraocular inflammation, Endophthalmitis, CTCAE | Altered Intercellular Communication | There were no cases of intraocular inflammation or endophthalmitis. | 25315663 |
| Inflammation, Coronary Artery Disease | Altered Intercellular Communication | Epicardial adipose tissue inflammation is related to vitamin D deficiency in patients affected by coronary artery disease. | 25315671 |
| Inflammation, Coronary Artery Disease | Altered Intercellular Communication | increased fat thickness and inflammation) have been described in coronary artery disease (CAD) patients. | 25315671 |
| Inflammation | Altered Intercellular Communication | Whether EAT inflammation may be linked to vitamin D deficiency is still unknown. | 25315671 |
| Inflammation | Altered Intercellular Communication | Whether maintaining an optimal vitamin D status may be helpful to reduce EAT inflammation and to prevent CAD and its progression needs further investigation. | 25315671 |
| Inflammation | Altered Intercellular Communication | All those protein aggregopathies show a state of chronic inflammation with microglia activation and production of proinflammatory cytokines. | 25315814 |
| Inflammation | Altered Intercellular Communication | In this context, it is hypothesized that the severity of the surrounding inflammation substantially contributes to disease progression and accelerated disease courses as seen in rpAD. | 25315814 |
| Communicable Diseases, Inflammation, Thalassemia | Altered Intercellular Communication | This information may be used to predict coexistent iron deficiency in b-thalassemia traits, in which concomitant infection or inflammation leads to normal ferritin levels. | 25316665 |
| Inflammation, Progranulins, Haploinsufficiency, Primary malignant neoplasm | Altered Intercellular Communication | All cause haploinsufficiency of progranulin, a protein involved in inflammation, tissue repair, and cancer. | 25317628 |
| Inflammation | Altered Intercellular Communication | In suspicious inflammation a further extended laboratory testing may become necessary (incl. | 25317649 |
| Inflammation | Altered Intercellular Communication | C-reactive protein (CRP) is a marker of arterial inflammation while lipoprotein-associated phospholipase A(2) (Lp-PLA(2)) is related to plaque instability. | 25317678 |
| Pneumonitis, Pneumonia | Altered Intercellular Communication | Female and estrogen-treated male mice show greater resistance to pneumococcal pneumonia, seen as greater bacterial clearance, diminished lung inflammation, and better survival. | 25317947 |
| Inflammation, Infiltration, Necrosis | Altered Intercellular Communication | Typically, there is no necrosis or acute inflammation, and giant cell infiltrates are frequent. | 25318988 |
| Inflammation, Neoplasm Metastasis, Traumatic injury | Altered Intercellular Communication | A relationship between inflammation and peritoneal metastasis has been reported; thus, we speculated that local inflammation resulting from chronic stimulus of mesh plugs and peritoneal trauma caused peritoneal metastasis at the repair sites. | 25319214 |
| Inflammation | Altered Intercellular Communication | In vitro experiments on monocytes and macrophages indicated that RA-SF promoted the acquisition of pro-inflammatory markers (INHBA, MMP12, EGLN3, CCR2) but led to a significant reduction in the expression of genes associated with homeostasis and inflammation resolution (FOLR2, SERPINB2, IGF1, CD36), thus confirming the pro-inflammatory polarization ability of RA-SF. | 25319955 |
| Inflammation, Metabolic Syndrome X, ETV3 wt Allele | Altered Intercellular Communication | Metabolic syndrome (MetS) is associated with low-grade inflammation, which may harmfully affect bone. | 25322274 |
| Littré hernia, Inflammation, Necrosis | Altered Intercellular Communication | The definition of Littre's hernia is based upon the protrusion of a MD through a potential abdominal opening accompanied in some cases by incarceration, inflammation, or necrosis. | 25323188 |
| RANGAP1 wt Allele, Inflammation, Spongiosis | Altered Intercellular Communication | The following distinctive confocal features for SD have been identified: spongiosis, dermal inflammation and horizontal orientation of dilated blood vessels. | 25323385 |
| palladium, Inflammation | Altered Intercellular Communication | These findings suggest that local peritoneal inflammation could contribute to poor clinical outcomes in PD patients. | 25323428 |
| Inflammation, Acute appendicitis NOS (disorder) | Altered Intercellular Communication | The severity of appendix inflammation was observed and rated using ARFI imaging in patients diagnosed with acute appendicitis. | 25323836 |
| Inflammation, Appendicitis, CTCAE | Altered Intercellular Communication | ARFI imaging may be useful in guiding the clinical management of acute appendicitis, by helping its diagnosis and determining the severity of appendix inflammation. | 25323836 |
| Inflammation, Rosacea | Altered Intercellular Communication | Samples from 40 patients with clinicopathologic diagnosis of rosacea and facial skin tissue samples from 20 patients with no specific findings or milium without inflammation were retrieved. | 25323904 |
| Communicable Diseases, Inflammation | Altered Intercellular Communication | Inflammation is an essential protective part of the body's response to infection, yet many diseases are the product of inflammation. | 25323997 |
| Inflammation, Autoimmune Diseases, Tissue damage, Diabetes Mellitus, Heart Diseases, Rheumatoid Arthritis | Altered Intercellular Communication | For example, inflammation can lead to autoimmune disease and tissue damage, and is a key element in chronic health conditions such as heart disease, diabetes, rheumatoid arthritis, and also drives changes associated with aging. | 25323997 |
| Inflammation, Psychiatric Res. Interview f. Substance and Mental Disorders | Altered Intercellular Communication | Animal models therefore provide a prism through which the role of inflammation in health and disease can be viewed, and are important means by which to dissect mechanisms and identify potential therapies to be tested in the clinic. | 25323997 |
| Inflammation, Disease | Altered Intercellular Communication | The main goal was to bring together experts from biotechnology and academic organizations to examine and describe critical pathways in inflammation and place these pathways within the context of human disease. | 25323997 |
| Inflammation, Primary malignant neoplasm | Altered Intercellular Communication | Interleukin-33 (IL-33) is a newly discovered proinflammatory cytokine belonging to the IL-1 cytokine family and involved in the development of chronic inflammation and cancer. | 25324197 |
| Inflammation, Neoplasms | Altered Intercellular Communication | Forty-nine patients were confirmed to have tumor recurrence and 13 patients were confirmed to have inflammation by pathology. | 25324947 |
| Inflammation, Myocarditis, CTCAE 5.0, Cardiomyopathies | Altered Intercellular Communication | Eosinophilic myocarditis is a rare condition in which inflammation of the heart results in an infiltrative cardiomyopathy that is often difficult to diagnose in the acute setting. | 25325192 |
| vascular inflammations, Obesity | Altered Intercellular Communication | Enhanced vascular inflammation is implicated as a pathophysiologic mechanism but obesity is confounding. | 25325463 |
| Slow shallow breathing, Inflammation, Hypoxemia, Apnea | Altered Intercellular Communication | The intermittent hypoxemia, rather than the number of apneas and hypopneas, appears to be primarily associated with enhanced inflammation. | 25325463 |
| Communicable Diseases, Inflammation, Dyssomnias | Altered Intercellular Communication | Sleep disturbance and aging are associated with increases in inflammation, as well as increased risk of infectious disease. | 25325509 |
| Inflammation, sleep loss | Altered Intercellular Communication | Older adults exhibit reduced toll-like receptor 4 stimulated cellular inflammation that, unlike in younger adults, is not activated after a night of partial sleep loss. | 25325509 |
| Communicable Diseases, Inflammation, Inflammatory disorder, sleep loss | Altered Intercellular Communication | Whereas sleep loss increases cellular inflammation in younger adults and may contribute to inflammatory disorders, blunted toll-like receptor activation in older adults may increase the risk of infectious disease seen with aging. | 25325509 |
| Inflammation | Altered Intercellular Communication | For patients with T2DM and CP, hyperglycemic status may exacerbate the inflammation state of gingival tissue by activating the NLRP3 pathway, and this abnormal host inflammatory response may contribute to further tissue breakdown. | 25325516 |
| Inflammation, diabetic | Altered Intercellular Communication | Compared with nondiabetic plaques, diabetic plaques had more inflammation and oxidative stress, along with a lesser SIRT6 expression and collagen content. | 25325735 |
| Inflammation, Polyneuropathy | Altered Intercellular Communication | Differential association between biomarkers of subclinical inflammation and painful polyneuropathy: results from the KORA F4 study. | 25325880 |
| vascular inflammations | Altered Intercellular Communication | Painful DSPN is linked to systemic subclinical and vascular inflammation in the older population independent of anthropometric, lifestyle, and metabolic confounders. | 25325880 |
| Inflammation, Hepatitis | Altered Intercellular Communication | Hepatitis is a descriptive term given for any inflammation of the liver. | 25325934 |
| Vasculitis, Haiti, Blood Vessel, Atherosclerosis | Altered Intercellular Communication | HT is associated with chronic vascular inflammation and remodeling, contributing to progressive vascular damage, and atherosclerosis. | 25326158 |
| Inflammation, Ulcerative Colitis | Altered Intercellular Communication | We present a case of a 21-year-old woman who underwent colectomy for ulcerative colitis and later presented with new onset severe reversible inflammation of the upper respiratory tract. | 25326560 |
| Mesenteric Panniculitis, Mesentery, Inflammation, Fibrosis Assessment | Altered Intercellular Communication | Mesenteric panniculitis pertains to a group of uncommon disorders named sclerosing mesenteritis that present with different levels of inflammation and fibrosis of the small bowel mesentery. | 25326572 |
| Communicable Diseases, Inflammation | Altered Intercellular Communication | Circulating lipopolysaccharides (LPSs), associated with both infection and inflammation, may arise from the gastrointestinal tract microbiota, and the levels may be affected by daily nutrition. | 25326898 |
| Inflammation, Neoplasms | Altered Intercellular Communication | It may be originated from a desmoplastic reaction of the retroperitoneum to the presence of malignant cells, to the action of cytokines secreted by the tumor or a reactive inflammation. | 25327326 |
| Gastroesophageal reflux disease, Inflammation, Barrett Esophagus | Altered Intercellular Communication | The severity of abnormal acid reflux occuring parallel with the incompetent function of the damaged LES triggers not only inflammation in the gastroesophageal junction (GEJ), but also metaplastic process, and the development of Barrett's esophagus. | 25327403 |
| Inflammation, Diabetes Mellitus, Non-Insulin-Dependent | Altered Intercellular Communication | We tested a mediational model in which chronic financial strain among African American women contributes to elevated serum inflammation markers, which, in turn, lead to increased haemoglobin A1C (HbA1c) levels and risk for type 2 diabetes. | 25327694 |
| Inflammation, Diabetes Mellitus, Non-Insulin-Dependent | Altered Intercellular Communication | Findings have implications for interventions that boost economic security and foster effective coping as well as medical interventions that reduce serum inflammation to prevent the onset of type 2 diabetes. | 25327694 |
| Vascular Diseases, Pterygium Of Conjunctiva And Cornea, Conjunctivitis, Glaucoma, CTCAE, Disease | Altered Intercellular Communication | Cases with a history of glaucoma or glaucoma suspect, prior pterygium surgery, pterygium with concurrent ocular surface and lid disease, conjunctival inflammation and scarring, pseudo-pterygium or collagen vascular disease were excluded. | 25327918 |
| Liver carcinoma | Altered Intercellular Communication | Dynamic changes of the inflammation-based index predict mortality following chemoembolisation for hepatocellular carcinoma: a prospective study. | 25327965 |
| FAM126A gene | Altered Intercellular Communication | The inflammation-based index (IBI) has previously been shown to independently predict overall survival (OS) in all stages of HCC. | 25327965 |
| Inflammation, Ischemia | Altered Intercellular Communication | No signs of inflammation during knee surgery with ischemia: a study involving inhaled nitric oxide. | 25328284 |
| ARCN1 gene, Inflammation, Chronic Obstructive Airway Disease | Altered Intercellular Communication | Chronic obstructive pulmonary disease (COPD) is characterized by chronic pulmonary and systematic inflammation. | 25329073 |
| Inflammation, Lung Neoplasms | Altered Intercellular Communication | Lung tumors showed higher inflammation than gastrointestinal ones. | 25329228 |
| Inflammation, Urolithiasis, physiopathological | Altered Intercellular Communication | Urothelial dysfunction and increased suburothelial inflammation of urinary bladder are involved in patients with upper urinary tract urolithiasis--clinical and immunohistochemistry study. | 25329457 |
| Inflammation, Urolithiasis, physiopathological | Altered Intercellular Communication | To investigate the urothelial dysfunction and inflammation of urinary bladder in patients with upper urinary tract (UUT) urolithiasis through the results of cystoscopic hydrodistension and immunohistochemistry study. | 25329457 |
| Inflammation, Urolithiasis, physiopathological, Urinary Bladder | Altered Intercellular Communication | Urothelial dysfunction and increased suburothelial inflammation and apoptosis are highly prevalent in the bladders of UUT urolithiasis patients, indicating inflammation cross-talk between UUT and urinary bladder. | 25329457 |
| Inflammation, Overweight | Altered Intercellular Communication | Dietary patterns differently associate with inflammation and gut microbiota in overweight and obese subjects. | 25330000 |
| Inflammation, Pustulosis of Palms and Soles | Altered Intercellular Communication | Vesicular LL-37 contributes to inflammation of the lesional skin of palmoplantar pustulosis. | 25330301 |
| Gingivitis, Inflammation, Attachment (action) | Altered Intercellular Communication | The second group consisted of 28 patients, 41-70 years of age, with overt signs of gingival inflammation but no attachment loss (gingivitis group). | 25330403 |
| Airway structure, Allergy - Charge Type Reason | Altered Intercellular Communication | Evaluation of high-sensitivity serum CRP levels compared to markers of airway inflammation and allergy as predictors of methacholine bronchial hyper-responsiveness in children. | 25331535 |
| Refractory anemias, Inflammation, Rheumatoid Arthritis | Altered Intercellular Communication | To evaluate associations between lipid levels, inflammation, and rheumatoid arthritis (RA) disease activity, at baseline and during treatment, with the risk of major adverse cardiovascular events (MACE) in tocilizumab-treated patients with RA. | 25332171 |
| Tumor necrosis, Inflammation | Altered Intercellular Communication | Tumor necrosis factor-a (TNF) and toll-like receptors (TLR) are important mediators of inflammation. | 25332681 |
| Inflammation, Dental Plaque | Altered Intercellular Communication | The level of plaque accumulation and gingival inflammation with the use of lingual plate and bar dentures were determined and compared. | 25335375 |
| Inflammation, Granulation finding, Malignant Neoplasms | Altered Intercellular Communication | Clinical diagnosis based on 2-[18F]fluoro-2 deoxy-D glucose uptake is sometimes limited by the fact that 2-[18F]fluoro-2 deoxy-D glucose is taken up by not only malignant tumor cells but also macrophages and tissues with granulation or inflammation. | 25335527 |
| THANATOPHORIC DYSPLASIA, TYPE I (disorder), Tardive Dyskinesia | Altered Intercellular Communication | Overactivity of dopaminergic neurotransmission is a putative mechanism of tardive dyskinesia (TD). | 25336319 |
| ARCN1 gene | Altered Intercellular Communication | Exhaled Hydrogen Sulfide Predicts Airway Inflammation Phenotype in COPD. | 25336529 |
| Airway structure, ARCN1 gene | Altered Intercellular Communication | The role of exhaled H2S as a marker of airway inflammation and its relationship with COPD severity remain to be determined. | 25336529 |
| Airway structure, ARCN1 gene | Altered Intercellular Communication | Airway inflammation was classified in 77 COPD subjects based on the presence of inflammatory cells in induced sputum. | 25336529 |
| Hepatic schistosomiasis, Granulomatous inflammation, Pancreatitis, Hypermetabolism | Altered Intercellular Communication | F-18 FDG hypermetabolism in mass-forming focal pancreatitis and old hepatic schistosomiasis with granulomatous inflammation misdiagnosed by PET/CT imaging. | 25337288 |
| Hepatic schistosomiasis, Granulomatous inflammation, Pancreatitis | Altered Intercellular Communication | Postoperative pathology was consistent with chronic pancreatitis and old hepatic schistosomiasis associated with granulomatous inflammation of the liver. | 25337288 |
| Hepatic schistosomiasis, Granulomatous inflammation, Pancreatic carcinoma | Altered Intercellular Communication | This case of mass-forming pancreatitis and granulomatous inflammation in old hepatic schistosomiasis mimicked metastatic pancreatic cancer on PET/CT. | 25337288 |
| TNM Staging System, Neoplasms, Thyroid carcinoma, Inflammation | Altered Intercellular Communication | ER-alpha and ER-beta expression in differentiated thyroid cancer: relation with tumor phenotype across the TNM staging and peri-tumor inflammation. | 25338203 |
| Inflammation, Thyroid carcinoma | Altered Intercellular Communication | Thyroid cancer may express estrogen receptors (ERs) and various grades of peri-tumor inflammation. | 25338203 |
| Meningitis | Altered Intercellular Communication | The MRI performed showed pachymeningeal and leptomeningeal inflammation. | 25338348 |
| palladium, Inflammation | Altered Intercellular Communication | We previously reported that lower serum magnesium is associated with poorer nutrition status, impaired cellular health, and increased inflammation in peritoneal dialysis (PD) patients. | 25338428 |
| Inflammation, Primary malignant neoplasm, Breast Carcinoma | Altered Intercellular Communication | Chronic inflammation is suggested to be associated with specific cancer sites, including breast cancer. | 25339205 |
| Inflammation | Altered Intercellular Communication | Complete decompression of the pancreatic ducts in the head of pancreas and full length drainage of the main pancreatic duct from the head of pancreas to the tail may be important in the Frey procedure to prevent recurrence of acute inflammation. | 25339262 |
| Uremia, Inflammation | Altered Intercellular Communication | To explore the relation between high leptin and inflammation in uremic patients. | 25339482 |
| Uremia, Inflammation | Altered Intercellular Communication | The high level of leptin and correlated inflammation were involved in the initiation and development of uremia; moreover, leptin was an important mediator. | 25339482 |
| Hepatic inflammation | Altered Intercellular Communication | FXR agonist GW4064 alleviates endotoxin-induced hepatic inflammation by repressing macrophage activation. | 25339829 |
| Hepatic inflammation, Non-alcoholic Fatty Liver Disease | Altered Intercellular Communication | To examine the effect of farnesoid X receptor (FXR) activation by GW4064 on endotoxin-induced hepatic inflammation in nonalcoholic fatty liver disease (NAFLD) and the underlying mechanism. | 25339829 |
| Hepatic inflammation, Non-alcoholic Fatty Liver Disease | Altered Intercellular Communication | Activation of FXR by GW4064 alleviated hepatic inflammation induced by endotoxin in a murine NAFLD model fed an HF diet as reflected by reduced serum levels of aspartate aminotransferase and alanine aminotransferase. | 25339829 |
| Hepatic inflammation, Non-alcoholic Fatty Liver Disease | Altered Intercellular Communication | FXR activation attenuates LPS-induced hepatic inflammation in murine NAFLD by reducing expression of proinflammatory cytokines in macrophages. | 25339829 |
| Inflammation, Primary malignant neoplasm | Altered Intercellular Communication | The importance of inflammation is increasingly noticed in cancer. | 25340395 |
| ARCN1 gene, Alveolar, Colonization, Airway structure, Tissue damage | Altered Intercellular Communication | Colonization by bacteria may further synergize, amplify, or trigger pathways of tissue damage started by cigarette smoke, contributing to the characteristic airway inflammation and alveolar destruction of COPD. | 25340840 |
| Inflammation | Altered Intercellular Communication | are present in more severe COPD disease, and increase inflammation in a mouse model of smoke exposure. | 25340840 |
| vascular inflammations, Hypertension, CTCAE, Endothelial dysfunction | Altered Intercellular Communication | Interleukin 17 drives vascular inflammation, endothelial dysfunction, and arterial hypertension in psoriasis-like skin disease. | 25341795 |
| Inflammation, physiopathological | Altered Intercellular Communication | We aimed to test the hypothesis that overproduction of IL-17A in the skin leading to dermal inflammation may systemically cause vascular dysfunction in psoriasis-like skin disease. | 25341795 |
| Inflammation, Obesity | Altered Intercellular Communication | These findings point to the adaptive immune system as a potential mediator between obesity and insulin resistance or inflammation. | 25341798 |
| Inflammation | Altered Intercellular Communication | The formyl peptide receptor (FPR) subtype FPR2/ALX transduces pro-inflammatory responses and participates in the resolution of inflammation depending on activation. | 25341894 |
| Inflammation, Intracranial Aneurysm | Altered Intercellular Communication | Evidence has shown that inflammation acts as a critical contributor to the pathogenesis of intracranial aneurysm (IA), a potentially devastating clinical problem. | 25342285 |
| Inflammation | Altered Intercellular Communication | T cell immunoglobulin and mucin protein 3 (Tim-3) is a negative regulatory molecule and plays important roles in the inflammation process. | 25342285 |
| Uveomeningoencephalitic Syndrome, Inflammation | Altered Intercellular Communication | This study was set up to investigate the expression of IL-37 in Vogt-Koyanagi-Harada (VKH) disease and to explore its possible regulatory role during inflammation. | 25343528 |
| Uveomeningoencephalitic Syndrome, Intraocular inflammation | Altered Intercellular Communication | VKH patients treated with corticosteroids combined with CsA showed a regression of the intraocular inflammation, and treatment was associated with an enhanced IL-37 production. | 25343528 |
| Inflammation, Primary malignant neoplasm, Prostate carcinoma | Altered Intercellular Communication | In recent years the role of inflammation in cancer etiology has gained attention and several studies have suggested that acetylsalicylic acid and other nonsteroidal anti-inflammatory drugs may have chemopreventive activity and reduce the risk of prostate cancer. | 25343540 |
| Inflammation | Altered Intercellular Communication | Serum HMGB1 is elevated in patients with MG and may play a key role in the inflammation of the neuromuscular junction. | 25344065 |
| Inflammation, Neurogenic arthropathy, Diabetic Foot | Altered Intercellular Communication | Charcot neuro-osteoarthropathy (CN) is a rare complication of diabetic foot syndrome associated with chronic inflammation of the foot and severe, limb-threatening musculoskeletal deformities. | 25344769 |
| Communicable Diseases, Cardiac complication, Inflammation | Altered Intercellular Communication | Therefore, the aim of our study was to examine the influence of intimal infection and systemic inflammation on cardiovascular complications after coronary intervention. | 25344890 |
| Inflammatory Bowel Diseases | Altered Intercellular Communication | Non-invasive monitoring of inflammatory bowel disease is an unmet clinical need as patients in clinical remission may have residual mucosal inflammation preceding clinical relapse. | 25344905 |
| Inflammation, Fibrosis Assessment | Altered Intercellular Communication | The postoperative material was assessed by the patologist, and it was described focal chronic inflammation of the head of pancreas with fibrosis involving the wall of the duodenum. | 25345278 |
| Hepatic inflammation | Altered Intercellular Communication | Histopathologically, platelet area of the liver tissues was positively correlated with hepatic inflammation (P = 0.02). | 25345682 |
| Hypersplenism, Hepatic inflammation, Thrombocytopenia | Altered Intercellular Communication | Hepatic inflammation contributes to the accumulation of platelets in liver; therefore, in patients with high serum ALT level, improvement of thrombocytopenia by the elimination of hypersplenism was limited. | 25345682 |
| Necrotizing granulomatous inflammation, Inflammation, Bacterial Infections | Altered Intercellular Communication | A biopsy of the ileal mucosa revealed inflammation with noncaseating granulomas possibly due to bacterial infection. | 25346193 |
| Intraocular inflammation | Altered Intercellular Communication | Subconjunctival injection of XG-102, a JNK inhibitor peptide, in patients with intraocular inflammation: a safety and tolerability study. | 25347151 |
| Coma, Post-Head Injury, Inflammation | Altered Intercellular Communication | Twenty patients with post-surgery or post-traumatic intraocular inflammation were assigned to 1 of the 4 dose escalating (45, 90, 450, or 900 mg XG-102) groups of 5 patients each. | 25347151 |
| Intraocular inflammation | Altered Intercellular Communication | All patients experienced a decrease in intraocular inflammation as of 24 h post-administration and this decrease was sustained up to 28 days thereafter. | 25347151 |
| Inflammation, Fibrosis Assessment | Altered Intercellular Communication | Cystic fibrosis airway epithelium remodelling: involvement of inflammation. | 25348090 |
| Inflammation, Fibrosis Assessment | Altered Intercellular Communication | Chronic inflammation is a hallmark of cystic fibrosis (CF) lung disease and airway epithelium damage and remodelling are important components of lung pathology progression in CF. | 25348090 |
| Inflammation, Basal cell hyperplasia | Altered Intercellular Communication | In comparison to non-CF epithelium, CF epithelium regeneration in the absence of exogenous inflammation was higher and exhibited basal cell hyperplasia. | 25348090 |
| Inflammation, Nesidioblastosis | Altered Intercellular Communication | This remodelling, together with goblet cell hyperplasia induced by exogenous inflammation and alteration of ciliated cell differentiation, may worsen mucociliary clearance impairment, leading to injury. | 25348090 |
| Inflammation | Altered Intercellular Communication | Inflammation may represent a common physiological pathway linking both short and long sleep duration to mortality. | 25348127 |
| Inflammation, Pneumonia | Altered Intercellular Communication | Since aged pneumonia patients often have repeated episodes of aspiration pneumonia, the pathogenesis may involve chronic inflammation. | 25348279 |
| Inflammation, Pneumonia | Altered Intercellular Communication | No previous studies have examined chronic inflammation or vascular changes in aspiration pneumonia or its mouse models. | 25348279 |
| Inflammation | Altered Intercellular Communication | In the lung, the aspiration model showed the presence of chronic inflammation and exaggerated lymphangiogenesis. | 25348279 |
| Inflammation | Altered Intercellular Communication | Human lung samples also showed the presence of chronic inflammation and exaggerated lymphangiogenesis, suggesting the relevance of the model to the disease. | 25348279 |
| Kidney Failure, Chronic, Inflammation, Cardiovascular Diseases | Altered Intercellular Communication | Patients with end-stage renal disease, especially those with inflammation, are at an increased risk of premature mortality, primarily because of cardiovascular disease. | 25348369 |
| Inflammation, Bronchopulmonary Dysplasia | Altered Intercellular Communication | The role of inflammation in the bronchopulmonary dysplasia (BPD) survivors is indistinct. | 25348705 |
| Inflammation, Carcinogenesis, Infection | Altered Intercellular Communication | Infections and inflammation in the prostate play a critical role in carcinogenesis, and S100A8 and S100A9 are key mediators in acute and chronic inflammation. | 25348783 |
| Inflammation, Brain Injuries | Altered Intercellular Communication | IATH did not affect biological markers of inflammation or brain damage or clinical outcome. | 25348858 |
| Inflammation, Primary malignant neoplasm | Altered Intercellular Communication | Systemic inflammation as evidenced by the Glasgow prognostic score (GPS) predicts cancer-specific survival in various types of cancer. | 25348884 |
| Hippocampal atrophy | Altered Intercellular Communication | This study shows an association between calcified cysticerci and hippocampal atrophy and raises the possibility of an inflammation-mediated hippocampal damage as the responsible mechanism for these findings. | 25349375 |
| Inflammatory Bowel Diseases, Inflammation, Neoplasms, Colorectal Neoplasms, CRNKL1 wt Allele | Altered Intercellular Communication | Chronic inflammation plays a key role in the pathogenesis of colorectal neoplasia (CRN) associated with inflammatory bowel disease, but it is not clear whether inflammation is a cause or an effect of tumours in sporadic CRN. | 25350634 |
| Inflammation, Cerebral Infarction | Altered Intercellular Communication | Mounting evidence has suggested that inflammation associated with interleukin (IL)-6 and T-helper (Th)17 cells, has a role in the development of atherosclerotic cerebral infarction (ACI). | 25351283 |
| Inflammation | Altered Intercellular Communication | IGF-I plays a role in the regulation of immunity, bone metabolism and inflammation. | 25352179 |
| Stomatitis, Deglutition Disorders, Inflammation | Altered Intercellular Communication | Most common grade >=3 adverse events (AEs) were dysphagia (30%), stomatitis (33%), and mucosal inflammation (27%). | 25352401 |
| Inflammation | Altered Intercellular Communication | This reinforces the important role of inflammation on the outcomes of this group of patients. | 25352506 |
| Inflammation, physiopathological | Altered Intercellular Communication | The lifestyle intervention reversed this insulin-induced vascular dysfunction in parallel to decreased inflammation level. | 25353072 |
| Inflammation, Neoplasms | Altered Intercellular Communication | Chronic inflammation is considered to be one of the hallmarks for tumor initiation and progression. | 25353097 |
| Inflammation, Atherosclerosis | Altered Intercellular Communication | Although both are novel cardiovascular risk factors associated with inflammation and atherosclerosis, the specific relationship between MBPS and serum GGT is unknown. | 25355010 |
| Diarrhea, Bronchospasm, Neoplasms, Abdominal Pain | Altered Intercellular Communication | Her tumor is functional, meaning it demonstrates hormonal hypersecretion which causes flushing, diarrhea, bronchospasm, and abdominal pain. | 25355025 |
| Inflammation, Critical Illness | Altered Intercellular Communication | In this pilot cohort of critically ill children, transfusion with older prestorage leukoreduced RBCs was associated with persistence of innate immune suppression and systemic inflammation. | 25355535 |
| Inflammation | Altered Intercellular Communication | Biopsy specimens from the oral mucosa revealed detachment of epithelial basement membrane and subepithelial lamina propria with slight chronic inflammation. | 25355555 |
| Necrotizing granulomatous inflammation, Necrosis | Altered Intercellular Communication | A biopsy of this lesion, taken through the duodenal wall, showed a histiocytic granulomatous inflammation with necrosis. | 25355744 |
| Nephritis, Interstitial, Tubulointerstitial nephritis and uveitis, Uveitis | Altered Intercellular Communication | Tubulointerstitial nephritis and uveitis (TINU) syndrome is characterized by tubulointerstitial and ocular inflammation. | 25356569 |
| Inflammation, Kit Ligand, human | Altered Intercellular Communication | There is accumulating evidence that inflammation plays a major role in the development of the slow coronary flow (SCF) phenomenon. | 25356814 |
| Immunologic Deficiency Syndromes, Chronic inflammation | Altered Intercellular Communication | Four patients with immune deficiency showed signs and symptoms of chronic inflammation. | 25356955 |
| Inflammation, Chronic abdominal pain, Ulcerative Colitis | Altered Intercellular Communication | We undertook a study to test the hypothesis that inflammation alters peripheral sensory mechanisms, thereby contributing to chronic abdominal pain in ulcerative colitis (UC). | 25358061 |
| Inflammation, Pain Distress Question | Altered Intercellular Communication | Mucosal nerve fiber density did not correlate with any measures of inflammation or pain. | 25358061 |
| Refractory anemias, Tumor necrosis, Rheumatoid Arthritis, Inflammation | Altered Intercellular Communication | Tumor necrosis factor (TNF) and, possibly, lymphotoxin alpha (LTa) signaling contribute to inflammation and rheumatoid arthritis (RA) pathogenesis. | 25359150 |
| Inflammation, Primary malignant neoplasm | Altered Intercellular Communication | The associations between S100A4 levels, inflammation, disease activity, muscle strength and cancer development were evaluated. | 25359220 |
| Malignant neoplasm of prostate, Kaposi Sarcoma, Prostate carcinoma, prostatitis, Structure of posterior cerebral artery | Altered Intercellular Communication | Human herpesvirus type 8 (HHV-8), a gamma herpesvirus associated with Kaposi's sarcoma, has been proposed as a candidate risk factor for prostate cancer (PCa) because of its detection in benign and malignant prostate specimens, and its relation with histologic prostatic inflammation. | 25359302 |
| Inflammation | Altered Intercellular Communication | Chronic inflammation in a long-term cohort of HIV-infected patients according to the normalization of the CD4:CD8 ratio. | 25360575 |
| Inflammation, Immunosenescence | Altered Intercellular Communication | As CD4:CD8 inversion is considered a marker of immune-senescence, we aimed to assess if it was associated with the chronic inflammation state in aging patients with HIV. | 25360575 |
| Inflammation | Altered Intercellular Communication | Chronic inflammation in patients aging with HIV does not seem to be directly dependent on the CD4:CD8 ratio. | 25360575 |
| Inflammation, Malignant Neoplasms | Altered Intercellular Communication | Chronic inflammation is often related to the occurrence and growth of various malignancies. | 25360699 |
| Airway structure | Altered Intercellular Communication | The wingless/integrated (Wnt) signaling pathways are responsible for several cellular processes, including airway inflammation and remodeling while cAMP-PKA cascade can activate the Wnt signaling. | 25360795 |
| Inflammation | Altered Intercellular Communication | Endothelial dysfunction associated with systemic inflammation can contribute to organ injury/failure following cardiac surgery requiring cardiopulmonary bypass (CPB). | 25360813 |
| Inflammation, Kidney Failure, Acute | Altered Intercellular Communication | Plasma and endothelial markers of inflammation [interleukin (IL) -6, -8, -10: von Willibrand factor (vWF) and angiopoeitin-2 (Ang-2)] and the AKI marker, neutrophil gelatinase-associated lipocalin (NGAL), were also measured by ELISA. | 25360813 |
| Inflammation, Necrosis, Pathological Dilatation, Stenosis Morphology, Occluded, Vasculitis, CTCAE | Altered Intercellular Communication | Coronary vasculitis is a group of conditions occurring either independently or associated with another diseases characterized by an inflammation of the blood vessel's wall and subsequent fibrinoid necrosis, occlusion, stenosis, or aneurismal dilatations. | 25361059 |
| Inflammation, Hematoma, Ischemia, Discitis, Hypersensitivity | Altered Intercellular Communication | No major complications like inflammation (especially spondylodiscitis), large haematomas requiring surgery, severe allergic reactions or spinal ischaemia occurred. | 25363255 |
| Inflammation, Prostate carcinoma, prostatitis | Altered Intercellular Communication | Prostate cancer patients with prostatitis showed significantly higher IL-2R expression than those without inflammation (p < 0.03). | 25363611 |
| Hyperparathyroidism, Secondary, Chronic Kidney Diseases, HYPERPARATHYROIDISM, NEONATAL SEVERE | Altered Intercellular Communication | Secondary hyperparathyroidism (SHPT) is one of the major complications of chronic kidney disease (CKD) and is associated with elevated serum intact parathyroid hormone (iPTH). | 25363733 |
| Granuloma, Intraocular inflammation | Altered Intercellular Communication | A large granuloma infiltrating optic nerve head was visible at funduscopic examination along with diffuse intraocular inflammation. | 25363855 |
| Inflammation, Observation Method - Coagulation, Musculoskeletal | Altered Intercellular Communication | Activation of markers of inflammation, coagulation and fibrinolysis in musculoskeletal trauma. | 25364904 |
| Inflammation, Observation Method - Coagulation, Wounds and Injuries | Altered Intercellular Communication | Traumatic injury induces changes in mediators of inflammation and coagulation, but the pivotal roles of inflammation and coagulation has not been precisely clarified. | 25364904 |
| Inflammation, Observation Method - Coagulation, Musculoskeletal | Altered Intercellular Communication | Therefore we have studied markers of inflammation and coagulation after a standardized musculoskeletal trauma like total hip replacement surgery. | 25364904 |
| Inflammation, Observation Method - Coagulation | Altered Intercellular Communication | Major musculoskeletal surgery causes changes of the inflammatory, coagulatory and fibrinolytic cascades in stable patients, but with no correlations between inflammation and coagulation and fibrinolysis. | 25364904 |
| Inflammation, Osseous metaplasia, Retinal Detachment, Tuberculosis, Pulmonary, Traumatic injury | Altered Intercellular Communication | Osseous metaplasia may occur in phthisis bulbi, usually caused by long-standing retinal detachment, ocular trauma, or inflammation. | 25364973 |
| Inflammation, Rupture, Plaque, Atherosclerotic | Altered Intercellular Communication | Biomechanics and inflammation in atherosclerotic plaque erosion and plaque rupture: implications for cardiovascular events in women. | 25365517 |
| Rupture, Inflammation, Dental Plaque | Altered Intercellular Communication | Given obvious differences in morphology between plaque erosion and rupture, we hypothesized that inflammation in general as well as the association between local mechanical strain and inflammation known to exist in plaque rupture may not occur in plaque erosion. | 25365517 |
| Inflammation, Dental Plaque | Altered Intercellular Communication | Using lesion-specific computer modeling of solid mechanics, we calculated the stress and strain distribution for each plaque and determined if there were any relationships with markers of inflammation. | 25365517 |
| Rupture, Inflammation, Dental Plaque | Altered Intercellular Communication | In contrast to classic plaque rupture, plaque erosion was not associated with markers of inflammation and mechanical strain. | 25365517 |
| Inflammation | Altered Intercellular Communication | It is hypothesized that unphysiologically increased loading in the AAA wall triggers biological tissue reaction, such as inflammation or regenerative processes, causing elevated FDG-metabolic activity. | 25365658 |
| Airway structure | Altered Intercellular Communication | Exhaled nitric oxide is a noninvasive measure of airway inflammation that can be detected by a handheld device. | 25366981 |
| Inflammation, HIV Infections | Altered Intercellular Communication | Our results show that HIV infection is associated with increased glucose metabolism in monocytes and that Glut1 expression by proinflammatory monocytes is a potential marker of inflammation in HIV-infected subjects. | 25367121 |
| Inflammation | Altered Intercellular Communication | PGC-1b overexpression leads to the attenuation of macrophage-mediated inflammation. | 25367151 |
| Refractory anemias, Inflammation, Rheumatoid Arthritis, Synovitis | Altered Intercellular Communication | To intra-individually assess the association of inflammation severity and cartilage composition measured by RAMRIS synovitis sub-score and delayed gadolinium-enhanced magnetic resonance imaging of the cartilage (dGEMRIC) of metacarpophalangeal (MCP) joints in patients with rheumatoid arthritis (RA). | 25367672 |
| Inflammation, Cartilage damage, Synovitis | Altered Intercellular Communication | To test the association of inflammation severity and cartilage damage and in order to eliminate inter-patient confounders, each patient's MCP 2 and 3 were dichotomized into the joint with more severe synovitis versus the joint with less severe synovitis for a paired Wilcoxon test of dGEMRIC value. | 25367672 |
| Inflammation | Altered Intercellular Communication | We have previously shown that chronic inflammation results in immunosuppression associated with CD247 downregulation in T lymphocytes. | 25368105 |
| Inflammation, Diabetes Mellitus, Non-Insulin-Dependent | Altered Intercellular Communication | Type 2 diabetes mellitus (T2DM) is known to be associated with chronic inflammation. | 25368105 |
| Inflammation, diabetic | Altered Intercellular Communication | Our results suggest the use of CD247 as a biomarker in diabetic patients for evaluating the state of chronic inflammation that contributes to morbidity and mortality in this disease and for the prediction of future cardiovascular events. | 25368105 |
| Inflammation | Altered Intercellular Communication | In the extracellular compartment, it exhibits cytokine-/adipokinelike properties, suggesting that it stands at the crossroad between metabolism and inflammation. | 25368373 |
| Tumor necrosis, Inflammation, Peptic Ulcer | Altered Intercellular Communication | Tumor necrosis factor a (TNF-a) encoded by TNFA is a key mediator in inflammation, a precursor condition for peptic ulceration. | 25368751 |
| Inflammation, Coronary Artery Disease, Non-cardiac chest pain | Altered Intercellular Communication | Inhibition of inflammation mediates the protective effect of atorvastatin reload in patients with coronary artery disease undergoing noncardiac emergency surgery. | 25369444 |
| Inflammation, Carcinogenesis, Papillary Urothelial Neoplasm | Altered Intercellular Communication | Chronic inflammation in the papillary urothelial neoplasm of low malignant potential (PUNLMP)may contribute to carcinogenesis, including that of BCa, via poorly understood mechanisms. | 25369740 |
| Acute and chronic inflammation | Altered Intercellular Communication | The cause is unknown but is associated with low estrogen levels and chronic vulval inflammation. | 25369765 |
| Airway structure, ARCN1 gene | Altered Intercellular Communication | Genetic variants in ADAM33 are associated with airway inflammation and lung function in COPD. | 25369941 |
| ARCN1 gene, Inflammation, Genes, Recessive | Altered Intercellular Communication | We found that T1, T2 and Q-1 were significantly associated with the changes of pulmonary function and components of cells in sputum of COPD, and T1 and Q-1 were significantly associated with cytokines and mediators of inflammation in airway of COPD in recessive models. | 25369941 |
| Airway structure | Altered Intercellular Communication | 10 haplotypes were significantly associated with transfer factor of the lung for carbon monoxide in the disease state, 4 haplotypes were significantly associated with forced expiratory volume in one second, and other haplotypes were associated with airway inflammation. | 25369941 |
| ARCN1 gene, Airway structure | Altered Intercellular Communication | We confirmed for the first time that ADAM33 was involved in the pathogenesis of COPD by affecting airway inflammation and immune response in an East Asian population. | 25369941 |
| Inflammatory Bowel Diseases, Inflammation, Colitis | Altered Intercellular Communication | Histological inflammation was found in 45 (68%) patients: 24 had a diagnosis of inflammatory bowel disease (IBD) while 21 reported miscellaneous conditions (5 microscopic colitis, 2 eosinophilic colitis, and 14 nonspecific chronic colitis). | 25369978 |
| Inflammation, Ichthyosis Bullosa of Siemens, Irritable Bowel Syndrome | Altered Intercellular Communication | The diagnosis in the 21 (32%) patients without inflammation was irritable bowel syndrome (IBS). | 25369978 |
| Inflammation | Altered Intercellular Communication | Median FC values were 268 ug/g (95% CI, 151-343) and 49 ug/g (95% CI, 23-101) in patients with and without inflammation, respectively (p = 0.0001). | 25369978 |
| Inflammatory Bowel Diseases, Inflammation, Ichthyosis Bullosa of Siemens | Altered Intercellular Communication | AUC value of FC was 0.811 (Se = 68.9%, Sp = 71.4%, PPV = 83.8%, and NPV = 56.3% with a cutoff value of 100 ug/g) for discriminating between patients with and without inflammation and 0.931 (Se = 87.5%, Sp = 90.5%, PPV = 91.3%, and NPV = 86.4% with a cutoff value of 150 ug/g) for discriminating between patients with IBS and IBD. | 25369978 |
| Gastrointestinal inflammation | Altered Intercellular Communication | FC appears to be a reliable noninvasive biomarker of intestinal inflammation useful to improve the appropriateness of colonoscopy requests. | 25369978 |
| Cessation of life, Inflammation, Sepsis | Altered Intercellular Communication | Nucleosomes are markers of cell death, and extracellular cell-free DNA has been suggested to play an important role in inflammation and has been demonstrated to correlate with severity and outcome in sepsis patients. | 25370187 |
| Inflammation, Ischemic stroke | Altered Intercellular Communication | Incremental predictive value of carotid inflammation in acute ischemic stroke. | 25370590 |
| Inflammation, Infiltration, diabetic | Altered Intercellular Communication | And there wss a lot of inflammation and foam cell infiltration in the radial artery intima of the diabetic patients. | 25370764 |
| Inflammation, diabetic | Altered Intercellular Communication | Gene sets upregulated in diabetic myotubes were associated predominantly with inflammation. | 25370850 |
| Inflammation, Fibrosis Assessment | Altered Intercellular Communication | In other words, fibrosis had advanced from the time of extensive cell infiltration in patients with IgG4-RKD and inflammation was relieved by corticosteroid. | 25371379 |
| Breast Carcinoma | Altered Intercellular Communication | Hormonal influences at critical periods may contribute to morphologic differences in the breast associated with breast cancer risk later in life. | 25371447 |
| Inflammation, Atherosclerosis | Altered Intercellular Communication | Leukotrienes (LTs), highly bioactive lipid mediators play a major role in inflammation, wound healing and in the development of atherosclerosis. | 25371530 |
| Inflammation, Translucent | Altered Intercellular Communication | Computed tomography showed gingival inflammation and lucencies of several teeth. | 25372197 |
| Communicable Diseases, Inflammation | Altered Intercellular Communication | Because there were no signs of infection or inflammation, surgical intervention was avoided. | 25372198 |
| Chorea Gravidarum | Altered Intercellular Communication | Both a genetic mutation and pregnancy-induced hormonal changes played possible roles in the development and progress of unilateral generalized KP in this patient. | 25372256 |
| Inflammation, Choroiditis, Multifocal | Altered Intercellular Communication | Idiopathic multifocal choroiditis with peripapillary zonal inflammation: a multimodal imaging analysis. | 25372332 |
| Unknown (origin) (qualifier value), Inflammation, Choroiditis, Chorioretinal atrophy | Altered Intercellular Communication | To report a case of idiopathic multifocal choroiditis with transient peripapillary zonal inflammation that was followed with multimodal imaging and explain the mechanism by which chorioretinal atrophy may occur. | 25372332 |
| Inflammation, Choroiditis, Chorioretinal atrophy, Inflammatory disorder, Atrophic | Altered Intercellular Communication | Multifocal choroiditis is an inflammatory disorder affecting the outer photoreceptors, ellipsoid layer, retinal pigment epithelium, and choroid; and areas of acute inflammation may improve over time but can also leave permanent chorioretinal atrophy including focal lesions or peripapillary zonal atrophy. | 25372332 |
| Vasculitis, Thrombophilia | Altered Intercellular Communication | Combined cases have mostly been attributed to rheological causes like thrombophilia, vessel wall inflammation, and mechanical compression. | 25372333 |
| Inflammation, Necrosis, Drug Allergy | Altered Intercellular Communication | An oral mucosal biopsy revealed V-shaped coagulative necrosis, intraepithelial and superficial acute and lymphoplasmacytic inflammation, consistent with drug hypersensitivity reaction. | 25372334 |
| Inflammatory abnormality of the eye | Altered Intercellular Communication | At 6 months of follow-up, her vision in the left eye was stable at 6/24 (Snellen) with no ocular inflammation. | 25372437 |
| Retinal Detachment, Inflammation, Hemorrhage | Altered Intercellular Communication | There was no retinal detachment, inflammation, or hemorrhage. | 25372445 |
| Inflammation, Vasculitis, CTCAE, Granuloma | Altered Intercellular Communication | Pulmonary biopsy disclosed chronic inflammation with no evidence of granuloma formation or vasculitis. | 25372516 |
| Intraocular inflammation, Endophthalmitis, CTCAE, Keratitis caused by infection | Altered Intercellular Communication | Chronic endophthalmitis should be suspected in patients who develop persistent intraocular inflammation after infectious keratitis. | 25372524 |
| Refractory anemias, Inflammation, Rheumatoid Arthritis | Altered Intercellular Communication | The erythrocyte sedimentation rate (ESR) and C-reactive protein (CRP) are two commonly used measures of inflammation in rheumatoid arthritis (RA). | 25373740 |
| Refractory anemias, Inflammation | Altered Intercellular Communication | As current RA treatment guidelines strongly emphasize early and aggressive treatment aiming at fast remission, optimal measurement of inflammation becomes increasingly important. | 25373740 |
| Inflammation, Polymyositis, Necrosis | Altered Intercellular Communication | We report on a novel finding whereby five of the seven patients who underwent multiple biopsies throughout their disease demonstrated a transformation of their histological diagnosis, with four progressing from having myofibre necrosis with minimal or no inflammation to a diagnosis of polymyositis. | 25373816 |
| Inflammation | Altered Intercellular Communication | PTX3 may represent a rapid marker of local inflammation. | 25373851 |
| ARCN1 gene, Inflammation | Altered Intercellular Communication | Cigarette smoking promotes inflammation in patients with COPD by affecting the polarization and survival of Th/Tregs through up-regulation of muscarinic receptor 3 and 5 expression. | 25375131 |
| Inflammation, Chronic Kidney Diseases | Altered Intercellular Communication | The progress of inflammation and oxidative stress in patients with chronic kidney disease. | 25375354 |
| Inflammation, Chronic Kidney Diseases | Altered Intercellular Communication | The variations and their correlation of inflammation and oxidative stress in chronic kidney disease (CKD) have not been thoroughly understood. | 25375354 |
| Inflammation, Chronic Kidney Diseases | Altered Intercellular Communication | Biomarkers of inflammation and oxidative stress were measured in a cohort of 176 patients with CKD ranging from stage 1 to 5 and 67 healthy controls. | 25375354 |
| Inflammation, Kidney Diseases | Altered Intercellular Communication | Correlation analysis in levels between inflammation and oxidative stress was also performed with estimated glomerular filtration rate (eGFR) using the Modification of Diet in Renal Disease (MDRD) formula. | 25375354 |
| Inflammation, Chronic Kidney Diseases | Altered Intercellular Communication | Inflammation and oxidative stress interacted with each other and played pivotal roles in the development of CKD. | 25375354 |
| Inflammation, Chronic Kidney Diseases | Altered Intercellular Communication | Variation in eGFR was parallel with the changes of oxidative stress and inflammation when CKD developing. | 25375354 |
| Inflammation | Altered Intercellular Communication | The lack of relationship between fecal M2-PK and calprotectin suggests that contributing factor(s) other than inflammation may be present. | 25376228 |
| Acute inflammation | Altered Intercellular Communication | Postoperative ghrelin administration is safe and may suppress protracted postoperative inflammation in patients who undergo esophagectomies. | 25377269 |
| Inflammation, Peri-Implantitis | Altered Intercellular Communication | Lhe research also revealed high prevalence of obligate piriodontak pathogens in areas of inflammation during periimplantitis. | 25377581 |
| intraepithelial, Inflammation, Hyperemia | Altered Intercellular Communication | It was shown that adenoids of the patients with complicated chronic adenoiditis less frequently exhibit markers of active inflammation, such as hyperemia, intraepithelial infiltration, and hemosiderophages. | 25377676 |
| Inflammation, Abnormal cardiovascular function, Disorder of mineral metabolism | Altered Intercellular Communication | Our results suggest that patients undergoing MHD with severe CCC or AAC have high degree of mineral metabolism disorder, inflammation, and cardiovascular function disorder. | 25377787 |
| APP gene, Inflammation | Altered Intercellular Communication | Therefore, we hypothesized that the inflammasome is a key mediator of initial inflammation in AAA formation. | 25378412 |
| Alveolar damage, Respiratory Failure, Lymphopenia, Pneumonitis | Altered Intercellular Communication | Our findings suggest that H7N9 influenza virus induced an immunological response towards overt pulmonary inflammation and systemic lymphopenia which led to intense alveolar damage and respiratory failure. | 25378539 |
| Inflammation, respiratory | Altered Intercellular Communication | It is strongly associated with complications, principally respiratory sepsis, and systemic inflammation. | 25379848 |
| Primary malignant neoplasm, Chronic inflammation, Malignant Neoplasms | Altered Intercellular Communication | Cross-sectional studies show that the degree of the defect may be associated with risk in some types of cancer, especially cancers associated with chronic inflammation. | 25379950 |
| Inflammation, Hypoxia, Anemia, hepcidin | Altered Intercellular Communication | Hepcidin is a small defensin-like peptide whose production by hepatocytes is modulated in response to anemia, hypoxia, or inflammation. | 25380934 |
| Inflammation, Disease | Altered Intercellular Communication | However, analysis of clinical response data showed that patients achieving low disease activity or remission seem to have a protective lipid profile, suggesting that better control of inflammation and disease activity can affect lipid metabolism. | 25381986 |
| Inflammation | Altered Intercellular Communication | The available evidence indicates that high inflammation interferes with lipid metabolism, whereas good control of the chronic inflammatory state may positively influence the lipid profile and cardiovascular risk. | 25381986 |
| Necrotizing granulomatous inflammation, Takayasu Arteritis | Altered Intercellular Communication | Takayasu arteritis is caused by an autoimmune process that results in chronic granulomatous inflammation. | 25383863 |
| Inflammation, Retinal ischemia | Altered Intercellular Communication | Optical coherence tomography can be useful in detecting retinal ischemia and the degree of inflammation in Takayasu retinopathy especially at the early stage. | 25383863 |
| Communicable Diseases, Thrombocytopenia | Altered Intercellular Communication | Spontaneous heparin-induced thrombocytopenia syndrome without any proximate heparin exposure, infection, or inflammatory condition: Atypical clinical features with heparin-dependent platelet activating antibodies. | 25383922 |
| Inflammation, Blood Clot, Hypoxia | Altered Intercellular Communication | A large proportion of AAA develops an intraluminal thrombus, which contributes to hypoxia, inflammation and tissue degradation. | 25384012 |
| Tumor necrosis | Altered Intercellular Communication | Monocytes and dendritic cells (DC) produce tumour necrosis factor (TNF)a during inflammatory processes, but secrete interleukin (IL)-10 simultaneously in order to balance the pro-inflammation. | 25384561 |
| Inflammation, Hyperlipidemia, Plaque, Atherosclerotic, Obesity, Dental Plaque | Altered Intercellular Communication | We concluded that sP-selectin, induced by systemic inflammation in conditions including obesity and hyperlipidemia, promoted atherosclerotic plaque and neointimal formation, plaque rapture and neointimal bleeding, further leading to AMI. | 25384966 |
| Cholesteatoma, Inflammation | Altered Intercellular Communication | Cholesteatoma represents progressive expansion of the keratinizing squamous epithelium in the middle ear with subsequent chronic inflammation in subepithelial connective tissues. | 25385222 |
| Cholesteatoma, Inflammation, Necrosis | Altered Intercellular Communication | The data suggest that in cholesteatoma, HMGB1 released from stressed or necrotic epithelial cells and binding to RAGE overexpressed in keratinocytes initiates molecular signaling that culminates in pro-inflammatory cytokine release and chronic inflammation. | 25385222 |
| Inflammation, Haiti | Altered Intercellular Communication | There may be a compensatory expansion of Treg at the sites of inflammation in tissues of PTC with HT contributing to the immune response suppression. | 25387566 |
| Tissue damage, Inflammation, Diabetes Mellitus | Altered Intercellular Communication | This finding provides a link among neutrophils, inflammation and tissue damage in diabetes. | 25387570 |
| Inflammation | Altered Intercellular Communication | Soluble urokinase plasminogen activator receptor (suPAR) is a highly sensitive marker that reflects increased inflammation and is positively correlated with pro-inflammatory biomarkers. | 25387618 |
| Inflammation | Altered Intercellular Communication | Our results underscore the importance of T lymphocytes during adipose tissue expansion, and the presence of potential compensatory mechanisms that may work to counteract adipose tissue inflammation, possibly through an increased number of T-regulatory cells. | 25388403 |
| Inflammation, Arthritis, Osteoporosis, Diabetes Mellitus | Altered Intercellular Communication | Compound A (CpdA), a selective glucocorticoid receptor agonist, reduces inflammation in murine arthritis models and does not induce diabetes or osteoporosis, thus offering an improved risk:benefit ratio in comparison with glucocorticoids. | 25389358 |
| Inflammation | Altered Intercellular Communication | Enhanced NO production increases the activities of the transcription factors p53 and nuclear factor kB (NF-kB) in several models of disease-associated inflammation. | 25389371 |
| Parkinson Disease, Inflammation, Muscular Atrophy | Altered Intercellular Communication | In rodent models of systemic inflammation, Parkinson's disease, or aging-related muscular atrophy, S-nitrosylation of SIRT1 correlated with increased acetylation of p53 and p65 and activation of p53 and NF-kB target genes, suggesting that S-nitrosylation of SIRT1 may represent a proinflammatory switch common to many diseases and aging. | 25389371 |
| Inflammation, Muscular Dystrophy, Duchenne, Doctor of Dental Medicine, muscle injury | Altered Intercellular Communication | In Duchenne muscular dystrophy (DMD), a genetic disruption of dystrophin protein expression results in repeated muscle injury and chronic inflammation. | 25390038 |
| Inflammation | Altered Intercellular Communication | Histology indicates that hyper-intense MRI foci correspond to areas of dystrophic lesions containing inflammation as well as regenerating, degenerating and hypertrophied myofibers. | 25390038 |
| Inflammation, Hypertrophy | Altered Intercellular Communication | In summary, we show that adipocyte hypertrophy is linked to increased inflammation in AT in obese children, thereby providing evidence that obesity-associated AT dysfunction develops in early childhood and is related to insulin resistance. | 25392242 |
| Inflammation | Altered Intercellular Communication | Complications in both groups were typically rare and self-limited, with recurrent inflammation being most common. | 25393037 |
| Inflammation, Obesity | Altered Intercellular Communication | Obesity, characterized by low-grade inflammation both in blood and white adipose tissue (WAT) is associated with increased C-reactive protein (CRP), a well-known acute phase protein. | 25393045 |
| Inflammation, AKAP4 protein, human | Altered Intercellular Communication | We also compared the same parameters after separating patients with "high" inflammation (HI, CRP>=20 mg/L, n=52) and with "low" inflammation (LI, CRP<20 mg/L, n=622). | 25393045 |
| Inflammation, Obesity | Altered Intercellular Communication | Our results suggest that WAT inflammation is a major contributor to increased CRP in obesity. | 25393045 |
| Nasopharyngeal carcinoma, Malignant Neoplasms | Altered Intercellular Communication | Several inflammation-based prognostic scoring systems, including Glasgow Prognostic Score (GPS), neutrophil to lymphocyte ratio (NLR) and platelet to lymphocyte ratio (PLR) have been reported to predict survival in many malignancies, whereas their role in metastatic nasopharyngeal carcinoma (NPC) remains unclear. | 25393117 |
| methyldopa, Inflammation | Altered Intercellular Communication | AMD is a multifactorial disorder but complement-mediated inflammation at the level of the retina plays a pivotal role. | 25393287 |
| Inflammation, Granulation finding | Altered Intercellular Communication | Microscopically, the lamina propria in all 12 cases contained inflammation and granulation tissue. | 25393329 |
| Degenerative polyarthritis, Inflammation | Altered Intercellular Communication | It is still controversial which cell types are responsible for synovial inflammation in osteoarthritic (OA) joints. | 25393692 |
| Inflammation, Pseudolymphoma | Altered Intercellular Communication | In the spleen, NIAM(m/m) mice had prominent white pulp expansion which correlated with enhanced increased reactive lymphoid hyperplasia and evidence of systemic inflammation. | 25393878 |
| Inflammation, Fatty degeneration | Altered Intercellular Communication | Inflammation and steatosis did not show any correlation with SWE values except for values from the left lobe, which showed correlation with steatosis (r = 0.24, P = .004). | 25393946 |
| Intraocular inflammation | Altered Intercellular Communication | Frequency and characteristics of intraocular inflammation after aflibercept injection. | 25394166 |
| Intraocular inflammation | Altered Intercellular Communication | To report the frequency and characteristics of intraocular inflammation after intravitreal aflibercept injection. | 25394166 |
| Intraocular inflammation | Altered Intercellular Communication | There were 28 cases of intraocular inflammation after a total of 5,905 aflibercept injections among 1,660 patients. | 25394166 |
| Inflammation, Critical Illness | Altered Intercellular Communication | Systemic inflammation often leads to complications in critically ill patients. | 25394242 |
| glycation, Damage, Inflammation | Altered Intercellular Communication | Activation of the receptor for advanced glycation end-products (RAGE) generates inflammatory cytokines, proteases, and oxidative stress and may link inflammation to subsequent organ damage. | 25394242 |
| Vasculitis, vascular inflammations | Altered Intercellular Communication | In contrast, patients with vascular inflammation detectable at imaging had higher PTX3 concentrations (P = 0.016) than those in which vessel inflammation was not evident, while CRP levels were similar. | 25394473 |
| Inflammation, Arteritis | Altered Intercellular Communication | These results support the contention that PTX3 reflects different aspects of inflammation than CRP and might represent a biomarker of actual arteritis in TA. | 25394473 |
| Dyspnea, Deglutition Disorders, Hyperostosis, Diffuse Idiopathic Skeletal | Altered Intercellular Communication | Progressive dysphagia and dyspnoea presenting after major neck trauma can occasionally be secondary to post-traumatic inflammation and mass effect associated with a calcified osteophytic anterior longitudinal ligament, a frequent finding in diffuse idiopathic skeletal hyperostosis, though rarely enough to cause such symptoms. | 25394498 |
| Inflammation, Peritonitis | Altered Intercellular Communication | Besides peritonitis, the most common complication, indicators of chronic inflammation are also present in patients treated by peritoneal dialysis. | 25394528 |
| Inflammation, Kidney Failure | Altered Intercellular Communication | There is an increased mortality risk in long-term hemodialysis patients of renal failure due to the chronic inflammation. | 25394530 |
| Cancer-related fatigue, Inflammation, Amyloidosis, MEFV gene | Altered Intercellular Communication | The current results indicate the germ-line mutations in both genetic biomarkers (MEFV and SAA1 genes) that are related to inflammation and amyloidosis processes may play a crucial role in CRF pathogenesis due to the long-term chronic inflammation. | 25394530 |
| Myelofibrosis, Chronic inflammation, Malignant Peripheral Nerve Sheath Tumor, Thrombocytosis, Polycythemia Vera | Altered Intercellular Communication | The Philadelphia-negative chronic myeloproliferative neoplasms - essential thrombocythemia (ET), polycythemia vera (PV), and myelofibrosis (MF) (MPNs) - have recently been shown to be associated with chronic inflammation, oxidative stress and accumulation of reactive oxygen species (ROS). | 25397683 |
| Gammopathy, Inflammation, Urticaria | Altered Intercellular Communication | The patients had chronic urticaria, IgM gammopathy and an elevation of the serum levels of inflammation markers. | 25398167 |
| Inflammation | Altered Intercellular Communication | Sonoelastography--a useful adjunct for parotid gland ultrasound assessment in patients suffering from chronic inflammation. | 25398237 |
| Sjogrens Syndrome", Inflammation, "Stensens duct", PEELING SKIN SYNDROME | Altered Intercellular Communication | Prospective analysis included 78 consecutive patients with parotid gland pathology: sialolithiasis (33), Stensen's duct stenosis (15), chronic inflammation (10), and primary Sjogren syndrome (pSS) (20) treated at the Department of Otolaryngology, Head and Neck Surgery of PUMS. | 25398237 |
| Inflammation, "Stensens duct | Altered Intercellular Communication | Mean elasticity values for pSS (111 Kilopascals (kPa), Stensen's duct stenosis (63 kPa), sialolithiasis (82 kPa), and chronic inflammation (77 kPa) were significantly higher than the mean value for healthy patients (24 kPa). | 25398237 |
| Inflammation, Fibrosis Assessment | Altered Intercellular Communication | In pSS the parenchyma was almost twice as stiff as in chronic inflammation (p=0.02), although subjective complaints were mostly mild or moderate, and the ultrasonographic picture did not present features of fibrosis. | 25398237 |
| Inflammation | Altered Intercellular Communication | Sonoelastography, by improving routine ultrasonographic assessment, might be a useful tool for parotid evaluations during the course of chronic inflammation. | 25398237 |
| Inflammation | Altered Intercellular Communication | Sputum induction is a non-invasive method for obtaining measurements of inflammation in the airways. | 25398249 |
| Inflammation, Liver Failure | Altered Intercellular Communication | Steroid treatment might be an option to prevent progress of life-threatening liver failure and liver transplantation in patients with hepatitis E-induced acute liver injury and high-grade inflammation. | 25398314 |
| Inflammation | Altered Intercellular Communication | No overall changes were observed in synovial inflammation score or the presence of T cells, B cells or macrophages. | 25398374 |
| Symptoms, Inflammation, Dryness of eye | Altered Intercellular Communication | These findings indicate that oxidative stress is associated with dry eye and that hyaluronic acid/vitamin B12 eye drops may attenuate oxidative stress and inflammation, improving dry eye symptoms. | 25398660 |
| Gingivitis | Altered Intercellular Communication | Moreover, the mean gingival index was 1.68+-0.31, which indicates a moderate gingival inflammation. | 25399215 |
| Inflammation | Altered Intercellular Communication | In fact, males showed more severe signs of gingival inflammation compared with females (p=0.001). | 25399215 |
| Inflammation, Dental Plaque | Altered Intercellular Communication | Interestingly, the age was not related either to the gingival inflammation (p=0.13), or to the amount of plaque accumulation (p=0.17). | 25399215 |
| Osteolysis | Altered Intercellular Communication | Genetic variation within inflammatory signaling and bone turnover pathways may play a role in susceptibility to osteolysis. | 25399506 |
| Inflammation, Mild cognitive disorder, millicurie, Data types - Address | Altered Intercellular Communication | Positron emission tomography studies detected Ab deposition and inflammation in the brains of subjects with amnestic mild cognitive impairment (MCI) before the onset of AD. | 25399811 |
| Inflammation, Data types - Address | Altered Intercellular Communication | Given the role of a7 nAChR in Ab deposition and inflammation, tropisetron represents an attractive potential therapeutic drug to delay or prevent MCI and AD. | 25399811 |
| Inflammation, Prostate carcinoma | Altered Intercellular Communication | The possible relationship of inflammation derived from dietary exposures with prostate cancer risk has not been investigated. | 25400225 |
| Inflammation, Dermatologic disorders, Dermatitis | Altered Intercellular Communication | Bullous pemphigoid (BP) and dermatitis herpetiformis (DH) are skin diseases associated with inflammation. | 25400334 |
| Tissue damage, Inflammation | Altered Intercellular Communication | Mast cells may play an essential role in activating inflammation, which ultimately contributes to the tissue damage observed in BP and DH. | 25400334 |
| Communicable Diseases, Hemorrhage, Inflammation | Altered Intercellular Communication | No bleeding, inflammation or infection occurred in these patients. | 25400740 |
| Inflammation | Altered Intercellular Communication | TLR4 and TLR9 show significant correlation with the severity of inflammation. | 25400780 |
| Inflammation, Stomach Carcinoma, Gastritis | Altered Intercellular Communication | In superficial gastritis and atrophy/intestinal metaplasia the inflammation was predominately mediated by TLR4, while in gastric cancer the inflammation was mainly mediated by TLR9. | 25400780 |
| UBC protein, human, Inflammation | Altered Intercellular Communication | The patients enrolled in the study were both oncological patients with UBC and non-oncological patients with inflammation (14 patients). | 25400813 |
| Virus Diseases | Altered Intercellular Communication | Innate immunity to viral infection involves induction of the type I IFN response; however, dysfunctional regulation of this pathway leads to inappropriate inflammation. | 25401470 |
| Inflammation, Uveitis | Altered Intercellular Communication | Uveitis, or inflammation of the uveal tract (i.e., iris, ciliary body, and choroid), results from a heterogeneous collection of disorders of varying etiologies and pathogenic mechanisms. | 25403035 |
| Inflammation, melanoma | Altered Intercellular Communication | 25-Hydroxyvitamin D2 /D3 levels and factors associated with systemic inflammation and melanoma survival in the Leeds Melanoma Cohort. | 25403087 |
| ARCN1 gene, Chronic Obstructive Airway Disease | Altered Intercellular Communication | The Global Initiative defines COPD for chronic obstructive lung disease as an entirely preventable and treatable disease characterized by sputum production, bacterial colonisation, neutrophilic bronchial airway inflammation and poor health status. | 25403149 |
| Inflammation, Primary malignant neoplasm, Carcinoma of lung, Carcinogenesis | Altered Intercellular Communication | The present results indicate that associations of vitamin B6 with cancer may be related to increased catabolism of vitamin B6, in particular for lung cancer where inflammation may be largely involved in carcinogenesis. | 25404109 |
| Inflammation, Dysplasia, Primary malignant neoplasm, Thrombopoietin Receptor Agonist LGD-4665, HGD gene | Altered Intercellular Communication | The cases were divided into different groups according to the pathological diagnosis of normal bronchial mucosa, inflammation, low-grade dysplasia (LGD), high-grade dysplasia (HGD), and invasive cancer. | 25404270 |
| Inflammation, Primary malignant neoplasm, Thrombopoietin Receptor Agonist LGD-4665 | Altered Intercellular Communication | The Y values were different and statistically different between invasive cancer and LGD (P<0.001) and invasive cancer and inflammation (P=0.040), respectively. | 25404270 |
| Inflammation, Primary malignant neoplasm, Thrombopoietin Receptor Agonist LGD-4665 | Altered Intercellular Communication | Similarly, the V values between invasive cancer and LGD and inflammation and normal bronchial mucosa were different. | 25404270 |
| Inflammation, HGD gene | Altered Intercellular Communication | Lastly, the V values between normal bronchial mucosa and HGD and inflammation and normal bronchial mucosa were different. | 25404270 |
| Inflammation, Fibrosis Assessment | Altered Intercellular Communication | Strategies to mitigate age-dependent dysregulation in glycemia should therefore target systemic and/or local inflammation and fibrosis of the aged islet vasculature. | 25404292 |
| Systemic Inflammatory Response Syndrome, Pneumonia | Altered Intercellular Communication | Decreased TLR-2 expression was associated with the occurrence of SIRS and pneumonia, suggesting a role in the cause of postoperative inflammatory conditions. | 25405275 |
| Inflammation, Parasitic Diseases | Altered Intercellular Communication | Anthropometry, hemoglobin, serum ferritin, transferrin receptors, retinol-binding protein and zinc concentrations, inflammation status, urinary iodine concentration and parasite infection were measured. | 25405764 |
| Inflammation, Anemia, Sickle Cell | Altered Intercellular Communication | Here, we evaluate Epo level vs. renal function, oxygenation, and markers of inflammation for patients treated for sickle cell disease at our institution. | 25405915 |
| Inflammation, Hemolysis (biological function) | Altered Intercellular Communication | Higher Epo levels were seen in patients receiving hydroxyurea (HU), but no correlation with oxygenation, hemolysis, renal function, or inflammation was observed. | 25405915 |
| Inflammation, Peri-Implantitis | Altered Intercellular Communication | The levels of typical bone matrix molecules, including SPP1, BGLAP, and COL9A1, in patients with peri-implantitis were reduced, while the inflammation marker interleukin 8 (IL8) was highly expressed. | 25406169 |
| Autoinflammatory Syndrome, Inflammation, Pancreatitis, Bacterial sepsis, Gout, Candidemia, Infectious Mononucleosis, Infection, Rheumatoid Arthritis, Endotoxemia, Crohn Disease, Respiratory Tract Infections | Altered Intercellular Communication | The release of sTLR2 and sTLR4 was studied in in-vitro stimulations, as well as in-vivo during experimental human endotoxemia (n = 11, 2 ng/kg LPS), and in plasma of 394 patients with infections (infectious mononucleosis, measles, respiratory tract infections, bacterial sepsis and candidemia) or non-infectious inflammation (Crohn's disease, gout, rheumatoid arthritis, autoinflammatory syndromes and pancreatitis). | 25406630 |
| Communicable Diseases, Inflammation | Altered Intercellular Communication | sTLR4 had a similar area under the ROC curve [AUC] for differentiating infectious and non-infectious inflammation compared to CRP: 0.72 (95% CI 0.66-0.79) versus 0.74 (95% CI 0.69-0.80) [P = 0.80], while sTLR2 had a lower AUC: 0.60 (95% CI 0.54-0.66) [P = 0.0004]. | 25406630 |
| Sepsis, Inflammation, Observation Method - Coagulation | Altered Intercellular Communication | Activation of inflammation and coagulation was closely related and mutually interdependent in sepsis. | 25407675 |
| Inflammation, Diabetic Retinopathy | Altered Intercellular Communication | Circulating markers of inflammation and endothelial function, and their relationship to diabetic retinopathy. | 25407692 |
| Inflammation, Diabetic Retinopathy | Altered Intercellular Communication | To examine the relationships of serum markers of inflammation and endothelial function to diabetic retinopathy. | 25407692 |
| Inflammation, Obesity, Abdominal, Metabolic Syndrome X, ETV3 wt Allele, Glucose Intolerance (disease), Ventricular Dysfunction | Altered Intercellular Communication | Growing evidence demonstrates subtle left ventricular myocardial dysfunction in patients with metabolic syndrome (MetS), with central obesity, glucose intolerance and inflammation emerging as important contributors. | 25407698 |
| Inflammation, ETV3 wt Allele | Altered Intercellular Communication | Biological markers of MetS and inflammation as well as RV GLS (-21.8 +- 3.8 vs -24.3 +- 3.0%, P = 0.009) and systolic (P = 0.003) and early diastolic (P = 0.01) SR, but not TDI indexes, significantly improved after diet and exercise training, and vector velocity imaging data in MetS following the lifestyle intervention no longer differed from controls. | 25407698 |
| Hyperglycemia, Inflammation, Diabetes Mellitus, Non-Insulin-Dependent | Altered Intercellular Communication | In type 2 diabetes, acute hyperglycemia worsens endothelial function and inflammation,while resistance to GLP-1 action occurs. | 25407792 |
| Inflammation, Data types - Address | Altered Intercellular Communication | The crucial step in AD pathogenesis is the production of amyloid-b42 peptide, which causes chronic inflammation. | 25408215 |
| Abdominal Pain | Altered Intercellular Communication | Here we present a rare case of a 9 year old girl referred by her general practitioner due to severe right lower quadrant abdominal pain with a presumed diagnosis of acute appendiceal inflammation. | 25408729 |
| ARCN1 gene, Inflammation, Chronic Obstructive Airway Disease, Exacerbation | Altered Intercellular Communication | Chronic obstructive pulmonary disease (COPD) exacerbations are acute events of worsened respiratory symptoms and enhanced inflammation partly mediated by NF-kB activation. | 25409035 |
| ARCN1 gene, Inflammation | Altered Intercellular Communication | RelB, an NF-kB family member, suppresses cigarette smoke-induced inflammation but its expression in COPD is unknown. | 25409035 |
| Inflammation, Neoplasms | Altered Intercellular Communication | The platelet count, as an inflammation marker, is involved in the progress of tumor invasion. | 25409616 |
| Inflammation | Altered Intercellular Communication | We propose that low levels of haCBG in chronic inflammation may limit the availability of cortisol to inflammatory sites, perpetuating the inflammatory process. | 25409953 |
| Granulomatous inflammation | Altered Intercellular Communication | Imaging demonstrated an invasive process and a biopsy was taken, which showed granulomatous inflammation that stained positively for mycobacteria. | 25410031 |
| Refractory anemias, Rheumatoid Arthritis, Have Autoimmune or Inflammatory Condition | Altered Intercellular Communication | Taking autoimmune inflammation of rheumatoid arthritis as entry point, this paper discussed the clinical effect of horsetail mixture on rheumatoid arthritis (RA) and its mechanism. | 25410066 |
| Lupus Erythematosus, Discoid | Altered Intercellular Communication | Discoid lupus erythematosus may lead to significant orbital inflammation syndrome. | 25410119 |
| Inflammation, Lupus Erythematosus, Discoid | Altered Intercellular Communication | Ocular manifestations related to discoid lupus erythematosus are uncommon and few cases of eye inflammation are reported. | 25410119 |
| Inflammation | Altered Intercellular Communication | Inflammation may contribute to the pathophysiology underlying impaired bone metabolism. | 25410434 |
| Inflammation, Hemorrhage, Condylomata Acuminata, High-Grade Squamous Intraepithelial Lesions, Trichomonas Vaginitis | Altered Intercellular Communication | Risk factors for HSIL included being in age group of 46-55 years (adjusted odds ratio [aOR] = 1.15, 95% CI: 1.07-1.44, compared with the 25-35 age group), bleeding after intercourse (aOR = 2.08, 95% CI: 1.40-3.10), and presence of trichomonas vaginalis infection (aOR = 2.62, 95% CI: 1.35-5.07), cervical inflammation (aOR = 4.22, 95% CI: 3.39-5.26), and genital warts (aOR = 3.89, 95% CI: 2.54-7.70). | 25410572 |
| Hemorrhage, Condylomata Acuminata, High-Grade Squamous Intraepithelial Lesions, Trichomonas Vaginitis, Uterine Cervicitis | Altered Intercellular Communication | Women aged 46-55 years, those with a lower education level, those reporting bleeding after intercourse, and those affected by Trichomonas vaginalis infection, cervical inflammation and genital warts are at higher risk for HSIL. | 25410572 |
| Inflammation, Diabetes Mellitus | Altered Intercellular Communication | Peroxisome proliferator-activated receptor-g (PPARg) was implicated in several pathological conditions including diabetes and inflammation. | 25410618 |
| Deficiency of micronutrients, Malaria, Inflammation | Altered Intercellular Communication | Adjusting indicators of iron and vitamin A status based only on APP may inaccurately estimate the prevalence of micronutrient deficiencies in settings with a high prevalence of malaria and inflammation. | 25411038 |
| Crohn Disease, Inflammatory disease of mucous membrane | Altered Intercellular Communication | Multiple micronutrient (MN) deficiency morphologically mimics EE, and o-3 (n-3) polyunsaturated fatty acids reduce mucosal inflammation in Crohn disease. | 25411039 |
| Inflammation, Hypertension, CTCAE | Altered Intercellular Communication | Increased plasma DPP4 activity predicts new-onset hypertension in Chinese over a 4-year period: possible associations with inflammation and oxidative stress. | 25411054 |
| Inflammation, Hypertension, CTCAE | Altered Intercellular Communication | This finding may have important implications for understanding the effects of DPP4 in promoting inflammation and oxidative stress in the pathogenesis of hypertension. | 25411054 |
| palladium, Inflammation, Degenerative disorder | Altered Intercellular Communication | Central to this is the knowledge that inflammation is a known hallmark of PD and of many other degenerative diseases. | 25411230 |
| Inflammation, Fibrosis Assessment, Diabetes Mellitus, Hypertension, CTCAE, Chronic Kidney Diseases | Altered Intercellular Communication | Uncontrolled diabetes, inflammation, and hypertension are key contributors to progressive renal fibrosis and subsequent loss of renal function. | 25411467 |
| Inflammation, Aortic Aneurysm, atherosclerotic, Atherosclerosis | Altered Intercellular Communication | Unlike adults, in whom atherosclerosis, inflammation, and advanced age are typically contributing factors, aortic dissection in children is usually due to nonatherosclerotic causes.Aortic aneurysms can be asymptomatic when small but, when significantly enlarged, can compromise organ function and dissect, resulting in high mortality rates. | 25411855 |
| Necrotizing granulomatous inflammation, Sarcoidosis, Systemic disease, Obesity, Overweight | Altered Intercellular Communication | Sarcoidosis, a systemic disorder characterized by chronic granulomatous inflammation, occurs more frequently among US black women, as do overweight and obesity. | 25411869 |
| Inflammation, Sarcoidosis, Overweight, Obesity | Altered Intercellular Communication | Little is known about the relation of overweight and obesity, which induce chronic inflammation, to incidence of sarcoidosis. | 25411869 |
| Inflammation | Altered Intercellular Communication | Xanthogranulomatous inflammation (XGI) is a rare chronic inflammatory condition most commonly involving the kidneys and gallbladder. | 25412596 |
| Inflammation | Altered Intercellular Communication | Xanthogranulomatous inflammation (XGI) is a rare chronic inflammatory condition most commonly involving the kidneys and gallbladder. | 25412596 |
| Inflammation, Coronary Stenosis, Dental Plaque, Atherosclerosis | Altered Intercellular Communication | Multiple inflammatory pathways influence plaque stability, but direct assessment of endothelial inflammation at the site of coronary artery stenosis has largely been limited to pathology samples or animal models of atherosclerosis. | 25413339 |
| vascular inflammations, Electrocardiogram: myocardial infarction (finding), Dental Plaque | Altered Intercellular Communication | We conclude that increased VCAM-1 expression on EC and formation of EMP at the site of coronary plaque is positively correlated with the extent of vascular inflammation in patients with myocardial infarction. | 25413339 |
| Inflammation, Brucellosis, Lupus Erythematosus, Systemic, Lupus Erythematosus | Altered Intercellular Communication | Familial Mediterranean fever gene (MEFV) mutations and disease severity in systemic lupus erythematosus (SLE): implications for the role of the E148Q MEFV allele in inflammation. | 25413357 |
| Inflammation, Lupus Nephritis | Altered Intercellular Communication | In this regard, absence of the E148Q mutation in SLE nephritis may serve as a clue for further investigation into its role as a general modulatory polymorphism for inflammation. | 25413357 |
| Dermatitis, Atopic, Inflammation, Glaucoma, CTCAE | Altered Intercellular Communication | Open-angle glaucoma associated with severe atopic dermatitis (atopic glaucoma) tends to be severe and difficult to treat because of ocular surface/eye lid inflammation. | 25415644 |
| Inflammation, atherosclerotic | Altered Intercellular Communication | Stable phase post-MI patients have elevated VEGF levels correlated with inflammation markers, but not with atherosclerotic burden. | 25417001 |
| Inflammation, atherosclerotic | Altered Intercellular Communication | Furthermore, we investigated whether the values of VEGF correlate to either inflammation markers or the atherosclerotic burden. | 25417001 |
| Inflammation, atherosclerotic | Altered Intercellular Communication | We found that plasma levels of VEGF are increased in the stable phase after MI and correlate with inflammation cytokines, but not with the atherosclerotic burden. | 25417001 |
| Enteritis | Altered Intercellular Communication | MRE images were reviewed for presence of intestinal wall inflammation. | 25417129 |
| Inflammation, Metabolic Syndrome X | Altered Intercellular Communication | Inflammation and cardiovascular risk assessment in Moroccan obese patients with and without metabolic syndrome: importance of lipoproteins ratios. | 25417430 |
| Inflammation, Cardiovascular Diseases, Obesity, Atherosclerosis | Altered Intercellular Communication | Inflammation, reported as a link between obesity and cardiovascular disease, contributes to the development of atherosclerosis. | 25417430 |
| Inflammation, ETV3 wt Allele | Altered Intercellular Communication | In patients with MetS, lipoprotein profile alterations and low-grade inflammation were observed. | 25417430 |
| Inflammation, ETV3 wt Allele | Altered Intercellular Communication | Our study shows that Moroccan obese adults with MetS have altered lipoproteins profiles and suffer from low-grade inflammation. | 25417430 |
| Inflammation, Myocardial | Altered Intercellular Communication | Myocardial edema indicating acute inflammation was seen in one (14.3%) patient. | 25417517 |
| Inflammation | Altered Intercellular Communication | This may represent inflammation and a change in airway integrity, rather than increased secretion of this peptide. | 25417673 |
| Hypokalemia, Inflammation, Esophagitis, Toxic effect | Altered Intercellular Communication | Dose-limiting toxicities (Grade 2 esophagitis; Grade 3 aspartate aminotransferase increased, mucosal inflammation and hypokalemia) were reported at starting dose (1.5 mg trametinib/50 mg afuresertib once daily continuously), exceeding the MTD. | 25417902 |
| Fibrosis Assessment, Cardiovascular system | Altered Intercellular Communication | Galectin-3 is a marker of myocardial fibrosis and mediates aldosterone-induced cardiovascular inflammation and fibrosis. | 25418979 |
| Chronic lymphocytic inflammation, Pontine structure | Altered Intercellular Communication | Case 212: chronic lymphocytic inflammation with pontine perivascular enhancement responsive to steroids. | 25420171 |
| Inflammatory abnormality of the eye | Altered Intercellular Communication | Gene delivery of a viral anti-inflammatory protein to combat ocular inflammation. | 25420215 |
| methyldopa, Diabetic Retinopathy, Disease, Uveitis | Altered Intercellular Communication | Inflammation of the retina is a contributing factor in ocular diseases such as uveitis, diabetic retinopathy, and age-related macular degeneration (AMD). | 25420215 |
| Autoimmune Diseases, Inflammation, Systemic Vasculitis, Granulomatosis | Altered Intercellular Communication | Granulomatosis with polyangiitis (GPA or Wegener) is a systemic autoimmune disease with inflammation of small- and medium-size vessels. | 25420293 |
| Erythema, Orchitis | Altered Intercellular Communication | Then he experienced bilateral auricular inflammation and painful erythema of the ankle. | 25420560 |
| Granulomatous inflammation | Altered Intercellular Communication | Pathological findings of the meninges in WG has been reported to be granulomatous inflammation. | 25420562 |
| Inflammation, Psoriasis | Altered Intercellular Communication | The elevation of plasma YKL-40 in psoriasis can be associated not only with inflammation of the disease, but also with ED. | 25421412 |
| Allergic sensitization, Airway structure | Altered Intercellular Communication | We screened for risk factors from children's and their families' histories, and assessed the usefulness of common markers of allergic sensitisation of the airway as surrogates for airway inflammation and increased risk for adverse respiratory events. | 25421587 |
| Inflammation, Demyelination, Nerve Degeneration | Altered Intercellular Communication | Demyelination and neurodegeneration of cortical grey matter contribute to a more severe disease, and inflammation of the forebrain meninges associates with pathology of the underlying neocortical grey matter, particularly in deep sulci. | 25421634 |
| Demyelination, Arachnoiditis, Meningitis | Altered Intercellular Communication | We assessed the extent of meningeal inflammation of the cerebellum, another structure with a deeply folded anatomy, to better understand the association between subarachnoid inflammation and grey matter pathology in progressive MS. We examined demyelinating and neuronal pathology in the context of meningeal inflammation in cerebellar tissue blocks from a cohort of 27 progressive MS cases previously characterized on the basis of the absence/presence of lymphoid-like aggregates in the forebrain meninges, in comparison with 11 non-neurological controls. | 25421634 |
| Demyelination, Meningitis | Altered Intercellular Communication | Demyelination and meningeal inflammation of the cerebellum was greatest in those cases previously characterized as harbouring lymphoid-like structures in the forebrain regions. | 25421634 |
| Meningitis | Altered Intercellular Communication | Meningeal inflammation was mild to moderate in cerebellar tissue blocks, and no lymphoid-like structures were seen. | 25421634 |
| Inflammation | Altered Intercellular Communication | These data suggest that chronic inflammation is widespread throughout the subarachnoid space and contributes to a more severe subpial demyelinating pathology in the cerebellum. | 25421634 |
| Lymphohistiocytosis, Hemophagocytic, Acute inflammation, Chronic granulomatous disease | Altered Intercellular Communication | Infection-triggered hemophagocytic lymphohistiocytosis (HLH), which manifests itself as pathologic hyperactive inflammation, has been observed in subjects with CGD. | 25422023 |
| Science of Etiology, Acute inflammation | Altered Intercellular Communication | The initial diagnostic evaluation demonstrated pathologic hyperactive inflammation, meeting the HLH-2004 diagnostic criteria without an identified infectious etiology. | 25422023 |
| Immunologic Deficiency Syndromes, Communicable Diseases, Lymphohistiocytosis, Hemophagocytic, Acute inflammation | Altered Intercellular Communication | It serves as a reminder that both immunodeficiency and inflammatory disorders may share features of pathologic hyperactive inflammation and highlights the conundrum that clinicians face when treating HLH in the setting of an unresolved infection. | 25422023 |
| Adult Non-Hodgkin Lymphoma | Altered Intercellular Communication | Polymorphic variation of inflammation-related genes and risk of non-Hodgkin lymphoma for Uygur and Han Chinese in Xinjiang. | 25422198 |
| Adult Non-Hodgkin Lymphoma, RTEL1 gene | Altered Intercellular Communication | Polymorphisms of inflammation-related genes have been found to be associated with non-Hodgkin lymphoma (NHL) or some of its subtypes, but only a few relevant data have been reported in China. | 25422198 |
| RTEL1 gene | Altered Intercellular Communication | Our results showed that polymorphic variations of inflammation-related genes could be important to the NHL etiology of the Han population, and that these may only have limited influence on the Uygur population. | 25422198 |
| Granulomatous, Chronic inflammation, Necrotizing, Ulcer | Altered Intercellular Communication | Two biopsies of the ulcer were taken and reported as granulomatous, necrotising, with chronic inflammation (first), and as hyperplasic epidermis with linfocitary infiltrate and the presence of plenty of plasmatic cells (second). | 25422341 |
| Inflammation | Altered Intercellular Communication | Toll-like receptors (TLRs) are damage-associated molecular patterns receptors, which are essential in the activation of the inflammasome cascade, required for the initiation of inflammation. | 25423559 |
| Inflammation, Erythema | Altered Intercellular Communication | Deep erythema and inflammation after re-epithelialization of superficial wounds is a sign of scar formation. | 25424054 |
| Inflammation | Altered Intercellular Communication | Corticosteroids may prevent scarring by suppression of inflammation and fibroblast activity. | 25424054 |
| Inflammation, Pancreatitis, Pain Distress Question, Fibrosis Assessment, Exocrine pancreatic insufficiency, Atrophic | Altered Intercellular Communication | Chronic pancreatitis is characterized by inflammation, atrophy, fibrosis with progressive ductal changes, and functional changes that include variable exocrine and endocrine insufficiency and multiple patterns of pain. | 25424572 |
| Gastrointestinal tract structure | Altered Intercellular Communication | We investigated HIF-1a expression in chronic ischemic and inflammatory conditions of the human gastrointestinal (GI) tract. | 25425478 |
| Synovitis, Edema of bone marrow, Skin lesion, Orchitis, Tenosynovitis | Altered Intercellular Communication | We determined the apparent improvement of synovitis, periarticular inflammation, tenosynovitis and/or bone marrow edema by MRI after anti-TNF-a treatments in all the patients together with the improvement of skin lesions. | 25425546 |
| Inflammation, Vegetation, Necrosis, Bacterial Endocarditis | Altered Intercellular Communication | Of 47 patients, 33 (70.2%) had either very small or no vegetations but had focal necrosis and inflammation of valve tissue that supported the diagnosis of infective endocarditis. | 25425980 |
| Pancreatitis | Altered Intercellular Communication | The interleukin (IL)-23/IL-17 axis plays an important role in various inflammatory conditions but its function in acute pancreatitis (AP) is not well understood. | 25426616 |
| Inflammation, Chronic Periodontitis | Altered Intercellular Communication | The prevalence of gingival inflammation was 86%, and nearly 7% of the adolescents had chronic periodontitis. | 25427260 |
| Inflammation, Calculi | Altered Intercellular Communication | The prevalence of gingival inflammation was high, and both the debris and calculus levels were strongly associated with gingival status in these adolescents. | 25427260 |
| Periodontitis | Altered Intercellular Communication | Increased C-reactive protein levels have been found in all active inflammations, including periodontitis. | 25427270 |
| Inflammation, Periodontitis | Altered Intercellular Communication | Two-week treatment with a 0.1% chlorhexidine mouthwash slightly reduced the gingival inflammation associated with periodontitis. | 25427325 |
| Inflammation, GYPB gene, Sweet Syndrome | Altered Intercellular Communication | Sweet syndrome (SS) is a relatively rare pediatric diagnosis, with fewer than 80 pediatric cases reported in the literature, characterized by tender erythematous plaques and nodules associated with systemic inflammation. | 25427755 |
| Inflammation, Fever, CTCAE | Altered Intercellular Communication | All had fever, elevated markers of systemic inflammation, and typical skin lesions. | 25427755 |
| Inflammation, Observation Method - Coagulation, GDC AJCC Clinical Stage Terminology | Altered Intercellular Communication | The results suggest that levels of plasma TF and interleukin 18 are significantly increased in patients with ACS, and there is significant correlation between the two, indicating an interaction between inflammation and coagulation in patients with ACS and an important role of these two in the occurrence and development of such disease. | 25427791 |
| Cardiovascular morbidity, Inflammation, Obesity | Altered Intercellular Communication | Obesity is associated with increased cardiovascular morbidity and mortality, inflammation, and elevated cortisol levels. | 25429009 |
| Acute lymphocytic leukemia, Arteritis | Altered Intercellular Communication | Changes of sulfur dioxide, nuclear factor-kB, and interleukin-8 levels in pediatric acute lymphoblastic leukemia with bacterial inflammation. | 25430458 |
| Inflammation, leukemia, Gas Gangrene | Altered Intercellular Communication | Bacterial inflammation is a common complication in patients with leukemia, and sulfur dioxide (SO2) is a bioactive molecule in modulating Gram-negative bacilli infection. | 25430458 |
| Inflammation | Altered Intercellular Communication | SO2 may play an anti-inflammatory role during the process of inflammation by inhibiting the activation and transcription of NF-kB. | 25430458 |
| Inflammation, Vegetation | Altered Intercellular Communication | Moreover, in the absence of vegetations, detection of delayed enhancement representing endothelial inflammation of the cardiovascular structures can contribute to the diagnosis and treatment planning of IE. | 25430531 |
| Inflammation, Left ventricular systolic dysfunction, GDC AJCC Clinical Stage Terminology | Altered Intercellular Communication | This study evaluated the relationship between physical activity status and the development of left ventricular systolic dysfunction (LVSD) according to inflammation and sex in elderly patients who had had an ACS. | 25432196 |
| Degenerative polyarthritis, Inflammation | Altered Intercellular Communication | Osteoarthritis (OA) is defined by signs and symptoms of inflammation within the affected joint. | 25432384 |
| Inflammation, Renal cyst | Altered Intercellular Communication | Computed tomography findings were consistent with complex renal cysts and perilesional inflammation. | 25433426 |
| Inflammation, Fibromyalgia, Hepatobiliary Disorder, Abdominal Pain, Chronic liver disease | Altered Intercellular Communication | If abdominal pain was included in the model, etiology became nonsignificant, indicating that it may be central sensitization due to abdominal pain in patients with chronic liver disease that explains fibromyalgia symptoms rather than the etiology of liver disease or inflammation. | 25433921 |
| Necrosis, Fibrosis Assessment, Inflammatory disorder, Waldenstrom Macroglobulinemia, Retractile Mesenteritis | Altered Intercellular Communication | Sclerosing mesenteritis (SM) is a rare, benign inflammatory disorder of unknown etiology, affecting the membranes of the digestive tract that involves lymphoplasmacytic inflammation, fat necrosis, and fibrosis of the mesentery. | 25434322 |
| Dysplasia, Parakeratosis, Autofluorescence, Inflammatory disease of mucous membrane | Altered Intercellular Communication | We found no dysplasia, which emphasises that autofluorescence detects non-dysplastic lesions caused by mucosal inflammation and parakeratosis. | 25434724 |
| Reproductive dehiscence, Inflammation, Neoplasms, Communicable Diseases, Coma, Post-Head Injury, Lipoma, Myositis Ossificans, Aspects of congenital malformations, Hemangioendothelioma, Hemangioma, Malignant Neoplasms, Vascular anomaly | Altered Intercellular Communication | Final diagnoses were formally established through simple standard clinical and radiological evaluation in 19 patients (11.8%; benign tumors, seven patients; malformations, eight patients; post-traumatic lesions, two patients; infection and inflammation, one patient each); ultrasound exam in five patients (3.1%; hemangioendotheliomas, two patients, fascial dehiscence, hemangioma, and vascular malformation, one patient each); MRI in four patients (2.5%; three vascular malformations and one lipoma); CT in two cases (1.2%; vascular malformation and myositis ossificans), and radiological examinations associated with cell aspiration in 15 cases (9.3%; ten benign tumors and five malignant tumors). | 25435271 |
| Inflammation, Ischemia | Altered Intercellular Communication | Our data seems to support the role of chronic inflammation and ischemia in the development of RVO. | 25435748 |
| Inflammation, Obesity | Altered Intercellular Communication | Taken together, these results confirm the previously established notion of chronic low grade inflammation in obesity and further suggests a role for the LT pathway in obesity-associated development of insulin resistance in humans. | 25437865 |
| Inflammation, Osteoporosis, Cardiovascular Diseases | Altered Intercellular Communication | Osteoporosis and cardiovascular disease may share common biological pathways, with inflammation playing a role in the development of both. | 25437881 |
| Inflammation, Diabetes Mellitus, Insulin-Dependent | Altered Intercellular Communication | Inflammation in childhood type 1 diabetes; influence of glycemic control. | 25437887 |
| Diabetes Mellitus, Insulin-Dependent, Inflammation, Cardiovascular Diseases, Atherosclerosis | Altered Intercellular Communication | Patients with type 1 diabetes have increased mortality from cardiovascular disease, and inflammation is important in the development of atherosclerosis. | 25437887 |
| Inflammation, Atherosclerosis, Diabetes Mellitus | Altered Intercellular Communication | Our aim was to evaluate the extent of inflammation and the influence of glycemic control in the early phases of atherosclerosis in childhood type 1 diabetes. | 25437887 |
| Inflammation, Diabetes Mellitus, Insulin-Dependent, Hyperglycemia, Atherosclerosis | Altered Intercellular Communication | Our results indicate that inflammation may play an important role in the accelerated atherosclerosis in early type 1 diabetes, and that this process seems primarily driven by hyperglycemia. | 25437887 |
| Inflammation | Altered Intercellular Communication | To examine if overall diet quality is associated with cellular and soluble biomarkers of systemic inflammation in middle-aged individuals. | 25437888 |
| Inflammation, Primary malignant neoplasm, Cardiovascular Diseases | Altered Intercellular Communication | As the incidence of cardiovascular disease and cancer is directly correlated with the levels of inflammation, our findings might indicate a protective role of high-quality diet. | 25437888 |
| Inflammation, Sleep Apnea, Obstructive, Ischemic stroke | Altered Intercellular Communication | Association of inflammation and oxidative stress with obstructive sleep apnea in ischemic stroke patients. | 25439077 |
| Inflammation, "Reinkes edema | Altered Intercellular Communication | Cyclic tensile strain on vocal fold fibroblasts inhibits cigarette smoke-induced inflammation: implications for Reinke edema. | 25439508 |
| Reinkes edema", Carcinoma, Carpal Tunnel Syndrome, Inflammation | Altered Intercellular Communication | Our results demonstrate that Reinke edema patients have more extrovert personality characteristics in comparison to carcinoma patients and, importantly, CTS attenuates CSC-induced inflammation in HVFF. | 25439508 |
| Inflammation, Uveitis | Altered Intercellular Communication | In 19 nonglaucomatous, uveitic eyes with active inflammation, mean global and all sectoral RNFL measurements were greater than the normative 95th percentile. | 25439601 |
| Ulcerative Colitis | Altered Intercellular Communication | Ulcerative colitis (UC) is a chronic inflammatory condition. | 25440769 |
| Inflammation, Endothelial dysfunction, Pulmonary Hypertension | Altered Intercellular Communication | Chronic exposure to biomass fuel smoke has been implicated in the development of pulmonary hypertension and right ventricular pressure/volume overload through activation of inflammation, increase in vascular resistance, and endothelial dysfunction. | 25440802 |
| Inflammation, Female Genital Diseases, Unknown (origin) (qualifier value), Communicable Diseases, Fecal Impaction, nervous system disorder | Altered Intercellular Communication | Causes of urinary retention were mechanical obstruction in 14 patients (25%), infection or inflammation in 10 (18%), fecal impaction in 7 (13%), neurologic disorders in 6 (11%), gynecologic disorders in 4 (7%), and behavioral processes in 3 patients (5%); 12 patients (21%) were idiopathic. | 25440826 |
| Inflammation, Diabetes Mellitus, Non-Insulin-Dependent | Altered Intercellular Communication | The aim of this study was to determine the association between iron parameters and inflammation in obese individuals with and without type 2 diabetes mellitus (T2DM). | 25441587 |
| Inflammation, Polymorphonuclear Cell Infiltrate, Atherosclerosis | Altered Intercellular Communication | Atherosclerosis and vascular remodeling after injury are driven by inflammation and mononuclear cell infiltration. | 25441669 |
| Inflammation, Malnutrition, HD Term Type, Arterial Occlusive Diseases, CLU protein, human | Altered Intercellular Communication | Malnutrition or chronic inflammation was associated with poor outcome in HD patients with CLI due to infrapopliteal occlusive disease. | 25441673 |
| Allergic asthma, Inflammation | Altered Intercellular Communication | Allergic asthma is characterized by inflammation and airway remodeling. | 25443138 |
| Nonalcoholic Steatohepatitis, Inflammation | Altered Intercellular Communication | The indole derivative NecroX-7 improves nonalcoholic steatohepatitis in ob/ob mice through suppression of mitochondrial ROS/RNS and inflammation. | 25443620 |
| Post-Traumatic Stress Disorder, Trauma, Nervous System | Altered Intercellular Communication | Heavy drinking in PTSD is associated with partially neutralized neurotransmitter imbalance, but also with neuronal injury commonly observed in AUD. | 25444536 |
| Inflammation, Fibrosis Assessment | Altered Intercellular Communication | Inflammation is essential for the progression of fibrosis. | 25445207 |
| Fibrosis Assessment, Hepatic inflammation | Altered Intercellular Communication | The urokinase plasminogen activator and its receptor have been associated with hepatic inflammation and fibrosis in mice. | 25445207 |
| Inflammation, Neoplasm Metastasis | Altered Intercellular Communication | High serum concentrations of soluble urokinase plasminogen activator receptor (suPAR) are suggested to be involved in inflammation, tissue remodeling, and cancer metastasis. | 25445207 |
| Inflammation, Fibrosis Assessment, Non-alcoholic Fatty Liver Disease | Altered Intercellular Communication | suPAR levels were associated with the severity of fibrosis, particularly in NAFLD, but did not correlate with inflammation. | 25445207 |
| Inflammation, Fibrosis Assessment, Non-alcoholic Fatty Liver Disease | Altered Intercellular Communication | However, this is the first study to investigate suPAR as a biomarker in NAFLD, and the results indicate that suPAR may constitute a severity marker related to fibrosis and prognosis rather than reflecting inflammation. | 25445207 |
| Inflammation | Altered Intercellular Communication | Pulmonary colonization with periopathogens seems to be associated with increased local inflammation. | 25445885 |
| Inflammatory Bowel Diseases, Inflammation, Acute Coronary Syndrome | Altered Intercellular Communication | Inflammation plays a critical role in the pathophysiology of both inflammatory bowel disease and acute coronary syndrome. | 25446295 |
| Inflammation, Frailty, Cardiovascular Diseases | Altered Intercellular Communication | Frailty, geriatric conditions, cardiovascular diseases and WBC count have also been associated with low grade inflammation. | 25446500 |
| Inflammation, Disease | Altered Intercellular Communication | In this study, we observed that differential and total WBC counts do not seem to be associated with geriatric conditions but with CV diseases, low-grade inflammation and telomere length. | 25446500 |
| Inflammation, Tumor necrosis | Altered Intercellular Communication | Mucosal inflammation induced the overexpression of GPR40, GPR120, and several inflammatory cytokines, with correlations between ileal concentrations of tumor necrosis factor (TNF)-a and GPR expression levels; however, inflammation did not induce the expression of proglucagon, a precursor of GLP-2 in CD patients. | 25447053 |
| Inflammatory abnormality of the eye | Altered Intercellular Communication | Panuveitis was the most common type of ocular inflammation (28 eyes), independent of HIV status. | 25447116 |
| Inflammatory abnormality of the eye | Altered Intercellular Communication | Syphilis is an uncommon cause of ocular inflammation in both HIV-negative and HIV-positive patients. | 25447116 |
| Inflammation, Fibrosis Assessment, Injury of kidney | Altered Intercellular Communication | Effects of left ventricular assist device support on biomarkers of cardiovascular stress, fibrosis, fluid homeostasis, inflammation, and renal injury. | 25447345 |
| Inflammation, Fibrosis Assessment, Myocardial, Injury of kidney | Altered Intercellular Communication | Changes in markers of myocardial stress, fibrosis, inflammation, fluid homeostasis, and renal injury in this setting are unknown. | 25447345 |
| Inflammation, Dental Pulp Necrosis | Altered Intercellular Communication | In many cases, the crack extended to the pulp, leading to reactions with intensities ranging from acute inflammation to total pulpal necrosis. | 25447500 |
| Inflammation, Coronary Artery Vasospasm, Atherosclerosis | Altered Intercellular Communication | Differences and interactions between risk factors for coronary spasm and atherosclerosis--smoking, aging, inflammation, and blood pressure. | 25447646 |
| Inflammation, Injury of kidney | Altered Intercellular Communication | Label-free quantitative proteomics by nanoLC-MS/MS was applied to urine of severe AP patients and found that severe AP is accompanied with kidney injury and inflammation. | 25447703 |
| TAO brand of troleandomycin, Uveitis | Altered Intercellular Communication | Extraocular muscle inflammation in TAO improved with treatment. | 25448468 |
| Alzheimers Disease", Data types - Address, physiopathological | Altered Intercellular Communication | Since glutamate neurotransmission is disrupted in Alzheimer's disease (AD), NPR levels measured from plasma represent a potential biomarker for synaptic dysfunction associated with AD. | 25449907 |
| Hyperglycemia, Inflammation, Obesity | Altered Intercellular Communication | Further research is needed to harness this novel and beneficial property of E4orf1 to improve hyperglycemia despite chronic inflammation that is commonly present in aging and obesity. | 25450249 |
| Inflammation, Cystic Fibrosis | Altered Intercellular Communication | It is known that patients with cystic fibrosis have a chronic inflammation status and that b pancreatic cells are very sensitive to oxidative stress. | 25450813 |
| Degenerative polyarthritis, Inflammation, Weight decreased | Altered Intercellular Communication | To describe associations between total and regional body fat mass loss and reduction of systemic levels of inflammation (C-reactive protein (CRP) and interleukin-6 (IL-6)) in obese, older adults with osteoarthritis (OA), undergoing intentional weight loss. | 25450847 |
| Abdominal Fat, Inflammation | Altered Intercellular Communication | Loss of abdominal fat volume was also associated with reduced inflammation, independent of total body fat mass; although models containing measures of total adiposity yielded the best fit. | 25450847 |
| Inflammation, Mycoses, Lobomycosis | Altered Intercellular Communication | Jorge Lobo's disease is a rare mycosis characterized by chronic inflammation, which causes skin lesions in the absence of visceral dissemination. | 25450888 |
| Inflammation, Impaired cognition, millicurie | Altered Intercellular Communication | CHF5074 (CSP-1103) has been shown to improve cognition and reduce brain inflammation in patients with mild cognitive impairment (MCI). | 25450955 |
| Inflammation, Haemoconcentration | Altered Intercellular Communication | More volume was administered in younger patients and in patients with evidence of hemoconcentration and inflammation. | 25451185 |
| Inflammation, Chronic Kidney Diseases | Altered Intercellular Communication | Association between metabolically unhealthy overweight/obesity and chronic kidney disease: the role of inflammation. | 25451190 |
| Inflammation, Chronic Kidney Diseases | Altered Intercellular Communication | Inflammation might mediate at least part of the association between metabolic changes and CKD prevalence. | 25451190 |
| Inflammation, sleep loss | Altered Intercellular Communication | Sleep loss activates cellular inflammation and signal transducer and activator of transcription (STAT) family proteins in humans. | 25451613 |
| Inflammation, Cardiovascular Diseases, Dyssomnias, Diabetes Mellitus, Malignant Neoplasms, Arthritis | Altered Intercellular Communication | Sleep disturbance and short sleep duration are associated with inflammation and related disorders including cardiovascular disease, arthritis, diabetes mellitus, and certain cancers. | 25451613 |
| Inflammation, Inflammatory disorder, Malignant Neoplasms | Altered Intercellular Communication | Treatments that target short sleep duration have the potential to constrain inflammation and reduce the risk for inflammatory disorders and some cancers in humans. | 25451613 |
| Atrial Fibrillation by ECG Finding | Altered Intercellular Communication | Inflammation-induced atrial fibrillation: pathophysiological perspectives and clinical implications. | 25453387 |
| Inflammation | Altered Intercellular Communication | Growing evidence suggests that inflammation plays a significant role in the onset and recurrence of AF. | 25453387 |
| Inflammation | Altered Intercellular Communication | The role of inflammation in the pathogenesis of AF has important clinical implications of which many practitioners are unfamiliar. | 25453387 |
| Appendicitis, CTCAE | Altered Intercellular Communication | In this article, we describe a case of a 29-year-old male, who presents the emergency department with inflammation-induced AF, secondary to acute appendicitis. | 25453387 |
| Inflammation, High Sensitivity C-Reactive Protein Measurement | Altered Intercellular Communication | Subgroup analysis showed 40 participants without signs of low-grade inflammation (hsCRP<3 mg/l, subgroup 1) and 21 participants with low-grade inflammation at baseline (hsCRP>=3 mg/l, subgroup 2). | 25453395 |
| Inflammation, Multiple Sclerosis, Liver Dysfunction | Altered Intercellular Communication | It is unknown whether diets with a high dietary total antioxidant capacity (TAC) can modify oxidative stress, low-grade inflammation, or liver dysfunction, all of which are risk factors for multiple sclerosis disease. | 25453518 |
| Pancreatitis, Infectious colitis | Altered Intercellular Communication | Computed tomography scan of her abdomen was performed and revealed findings consistent with infectious colitis, without signs of pancreatic inflammation or other findings associated with pancreatitis. | 25453861 |
| Inflammation, Fibrosis Assessment, Necrosis | Altered Intercellular Communication | Morphological studies included analysis of growth pattern, cell proliferation (Ki-67/MIB1 expression) and parameters of intra- and peri-tumoral remodelling (inflammation, fibrosis and necrosis). | 25454198 |
| Granuloma, Pneumonia, Interstitial | Altered Intercellular Communication | Based on our findings in this series and the most recent publications of the subject, we propose the following set of diagnostic criteria for PPFE: multilobar subpleural and/or centrilobular fibrous interstitial pneumonia characterized by an extensive (>80%) proliferation of elastic fibers in nonatelectatic lung, along with absent to mild chronic inflammation, and absent to rare granulomas. | 25454481 |
| Inflammation | Altered Intercellular Communication | However, severity of inflammation appears to be a critical factor in disease pathogenesis. | 25454482 |
| Inflammation, Ischemic | Altered Intercellular Communication | Carotid inflammation on 18F-fluorodeoxyglucose positron emission tomography associates with recurrent ischemic lesions. | 25454641 |
| Inflammation, Ischemic stroke | Altered Intercellular Communication | Inflammation plays an important role in the development of ischemic stroke. | 25454641 |
| Inflammation, Ischemic, Carotid Atherosclerosis | Altered Intercellular Communication | We hypothesized that inflammation of carotid atherosclerosis, as measured by (18)F-fluorodeoxyglucose (FDG) uptake on positron emission tomography (PET), associates with the early recurrent ischemic lesions (ERILs). | 25454641 |
| Carotid Atherosclerosis | Altered Intercellular Communication | Increased carotid plaque inflammation, as measured by FDG uptake on PET, may be a useful marker for identifying patients with symptomatic carotid atherosclerosis who are at risk of recurrence. | 25454641 |
| Inflammation, cervical cancer | Altered Intercellular Communication | Elevated TLR9 levels without HPV clearance in persistently infected women could drive inflammation thereby contributing to cervical cancer risk. | 25454809 |
| Inflammation, Asthma | Altered Intercellular Communication | The lack of predictive value of any pathologic measure in infancy, reported here for the first time to our knowledge, demonstrates that pathologic processes determining the inception of asthma, which are as yet undescribed, are different from the eosinophilic inflammation associated with ongoing disease. | 25455519 |
| Airway structure | Altered Intercellular Communication | This study suggests that FENO values higher than 27ppb are likely to be abnormal and would reflect airway inflammation in children as those in the present study. | 25456527 |
| Cardiovascular morbidity, Inflammation | Altered Intercellular Communication | In addition, we examined the impact of physical activity changes over time on 2 known mediators of cardiovascular morbidity: parasympathetic tone and inflammation. | 25456561 |
| Inflammation, Asthma, Chronic Obstructive Airway Disease | Altered Intercellular Communication | In this cohort of patients with severe asthma, the majority displayed indices of persistent airflow limitation and eosinophilic inflammation despite high-dose corticosteroids, suggesting potential for eosinophil-targeted biotherapies. | 25456708 |
| Inflammation, "Alzheimers Disease", Data types - Address | Altered Intercellular Communication | Inflammation is a key factor in the onset and progression of Alzheimer's disease (AD). | 25456845 |
| Inflammation, Hypertension, CTCAE, Liver Cirrhosis | Altered Intercellular Communication | Inflammation, collagen deposition and tissue remodelling are involved in the pathogenesis and complications of cirrhosis with portal hypertension. | 25457205 |
| vascular inflammations | Altered Intercellular Communication | Galectin-3, a member of galectines, a family of b-galactoside-specific lectins, has been reported to propagate vascular inflammation. | 25457298 |
| Neurogenic Inflammation, Myalgia, CTCAE 5 | Altered Intercellular Communication | It is also known as centrally mediated myalgia associated with neurogenic inflammation. | 25457825 |
| Inflammation, Endothelial dysfunction, Kidney Diseases | Altered Intercellular Communication | Incipient nephropathy was associated with more pronounced alterations in vitamin B6 metabolism and stronger indications of endothelial dysfunction and inflammation. | 25458341 |
| Inflammation, Primary malignant neoplasm, Ulceration, CTCAE, Traumatic injury | Altered Intercellular Communication | This hierarchical model of stem cell genesis leads to a very low prevalence of cancer, unless the orderly progression of the hierarchy is disturbed by inflammation, ulceration or trauma. | 25459141 |
| Inflammation, neuroborreliosis, Polyneuritis | Altered Intercellular Communication | A unique case of adolescent neuroborreliosis presenting with multiple cranial neuritis and cochlear inflammation on magnetic resonance imaging. | 25459362 |
| Inflammation, Polyneuritis | Altered Intercellular Communication | Neuroimaging demonstrated cranial polyneuritis and right-sided cochlear inflammation. | 25459362 |
| hearing impairment, Inflammation, neuroborreliosis | Altered Intercellular Communication | Additionally, cochlear inflammation along with cranial nerve VIII inflammation may contribute to hearing loss in patients with neuroborreliosis. | 25459362 |
| Inflammation, Failure (biologic function) | Altered Intercellular Communication | Other major reasons for failure were inappropriate length of tube insertion in the primary group and inflammation in the revision group. | 25459376 |
| Inflammation, Failure (biologic function) | Altered Intercellular Communication | The most common cause of failure was medial migration of the Jones tube; however, inappropriate tube insertion in primary surgery and severe inflammation in revision may also be concerns. | 25459376 |
| Airway structure, ARCN1 gene | Altered Intercellular Communication | Clinical characteristics and airway inflammation profile of COPD persistent sputum producers. | 25459449 |
| ARCN1 gene, Airway structure | Altered Intercellular Communication | We hypothesized that COPD patients with persistent sputum production have a different profile of airway inflammation, and more severe clinical characteristics. | 25459449 |
| Airway structure, ARCN1 gene | Altered Intercellular Communication | To compare the airway inflammation profile and clinical characteristics of COPD persistent and non-persistent sputum producers. | 25459449 |
| Diastolic dysfunction, Inflammation, Heart failure, Monocytosis | Altered Intercellular Communication | Exaggerated inflammation and monocytosis associate with diastolic dysfunction in heart failure with preserved ejection fraction: evidence of M2 macrophage activation in disease pathogenesis. | 25459685 |
| Inflammation, Fibrosis Assessment, Heart failure, Myocardial lymphocytic infiltration | Altered Intercellular Communication | Heart failure with preserved ejection fraction (HFPEF) is a major health problem associated with myocardial leukocyte infiltration, inflammation, and fibrosis. | 25459685 |
| Inflammation, Monocytosis | Altered Intercellular Communication | Increased peripheral inflammation, monocytosis, and monocyte differentiation to anti-inflammatory/profibrotic M2 macrophages likely associate with HFPEF and its precedent asymptomatic LVDD phase. | 25459685 |
| Inflammation, Hypertension, CTCAE, Metabolic Syndrome X | Altered Intercellular Communication | No relationship of anti-ox LDL level with cognition, hypertension, metabolic syndrome, inflammation indicators and serum lipid levels was observed. | 25459919 |
| Inflammation, Pain Distress Question, Psychiatric, Disability, Liver Cirrhosis | Altered Intercellular Communication | Inflammation, psychiatric symptoms, and opioid use are associated with pain and disability in patients with cirrhosis. | 25460019 |
| Pain Distress Question, Inflammation, Psychiatric, Disability, Liver Cirrhosis | Altered Intercellular Communication | We investigated whether the pain and disability in patients with cirrhosis are associated with systemic inflammation and psychiatric symptoms. | 25460019 |
| Pain Distress Question, Inflammation, Psychiatric, Disability, Liver Cirrhosis | Altered Intercellular Communication | Pain and disability are common among patients with cirrhosis, and are associated with inflammation, psychiatric symptoms, and opioid use, which potentially are modifiable. | 25460019 |
| Pain Distress Question, Inflammation, Psychiatric | Altered Intercellular Communication | Although opioids are used commonly to treat pain, psychiatric symptoms and inflammation also might be treatment targets in this population. | 25460019 |
| Inflammation, Obesity, Abdominal, metabolic disturbance, Bipolar Disorder | Altered Intercellular Communication | The longitudinal association between inflammation and incident depressive symptoms in men: the effects of hs-CRP are independent of abdominal obesity and metabolic disturbances. | 25460540 |
| Inflammation, Obesity, Abdominal, metabolic disturbance, Bipolar Disorder | Altered Intercellular Communication | This cohort study evaluates whether the association between low-grade inflammation and incident depressive symptoms is independent of abdominal obesity and metabolic disturbances. | 25460540 |
| Obesity, Abdominal, metabolic disturbance | Altered Intercellular Communication | Further investigation into the role of abdominal obesity and metabolic disturbances in the inflammation-depression hypothesis is warranted. | 25460540 |
| Inflammation, Fracture | Altered Intercellular Communication | Low-grade inflammation is associated with fractures, while the relationship between inflammation and bone mineral density (BMD) is less clear. | 25460573 |
| Inflammation, Fracture | Altered Intercellular Communication | We infer that inflammation influence fracture risk in both women and men, although the biological mechanisms may differ between the genders. | 25460573 |
| Hepatitis C, Chronic, Hepatitis | Altered Intercellular Communication | Absolute quantification of serum microRNA-122 and its correlation with liver inflammation grade and serum alanine aminotransferase in chronic hepatitis C patients. | 25461662 |
| Hepatitis | Altered Intercellular Communication | However, there was no significant association between microRNA-122 and ALT serum levels or liver inflammation grades. | 25461662 |
| Carcinogenic Chlorinated Hydrocarbon, Injury of liver, Hepatitis | Altered Intercellular Communication | However, this biomarker for acute liver injury did not reflect the liver inflammation activity in CHC patients. | 25461662 |
| Inflammation | Altered Intercellular Communication | Prevention of ERM formation by aggressive control of inflammation is important. | 25462433 |
| Aneurysm, Inflammation, Iliac Aneurysm | Altered Intercellular Communication | Progression of perianeurysmal inflammation after endovascular aneurysm repair for inflammatory abdominal aortic and bilateral common iliac artery aneurysms. | 25462547 |
| Aneurysm, Inflammation, Aortic Aneurysm, Abdominal | Altered Intercellular Communication | The use of endovascular aneurysm repair (EVAR) to treat inflammatory abdominal aortic aneurysms (IAAAs) has been reported, and this procedure appears to be preferable to open surgical repair because of intraoperative difficulties related to inflammation. | 25462547 |
| Inflammation | Altered Intercellular Communication | The perianeurysmal inflammation worsened postoperatively, requiring the placement of a ureteric stent. | 25462547 |
| Inflammation | Altered Intercellular Communication | The only risk factor for IAA was the intraoperative grade of inflammation (P=0.028). | 25462984 |
| Inflammation | Altered Intercellular Communication | ASA score (odds ratio: 1.992, P=0.032) and the intraoperative grade of inflammation (odds ratio: 1.573, P=0.006) remained significant in the multivariate analysis for SSI. | 25462984 |
| vascular inflammations | Altered Intercellular Communication | Positive correlation between malondialdehyde-modified low-density lipoprotein cholesterol and vascular inflammation evaluated by 18F-FDG PET/CT. | 25463065 |
| vascular inflammations | Altered Intercellular Communication | Vascular inflammation, was measured as blood-normalized standardized (18)F-FDG uptake value, known as the target-to-background ratio (TBR) of carotid arteries. | 25463065 |
| vascular inflammations, atherosclerotic | Altered Intercellular Communication | Circulating MDA-LDL may be a more useful clinical biomarker for vascular inflammation within the atherosclerotic plaques than hsCRP or ADMA. | 25463065 |
| Inflammation, Endothelial dysfunction, Injury of kidney | Altered Intercellular Communication | Low density lipoprotein cholesterol (LDL-C) is associated with endothelial dysfunction, inflammation and increased vasoconstriction, which are involved in the development of contrast-induced acute kidney injury (CI-AKI). | 25463073 |
| Inflammation, Blood Clot | Altered Intercellular Communication | Coronary thrombus composition: links with inflammation, platelet and endothelial markers. | 25463088 |
| Vascular Diseases, Congenital Abnormality | Altered Intercellular Communication | Preliminary evidence suggests that intact parathyroid hormone (iPTH) and bone mineral abnormalities may contribute to the development of vascular disease and are associated with reduced survival in the general population. | 25463096 |
| Inflammation, Atherosclerosis | Altered Intercellular Communication | inflammation (CXCR4, CXCL2, PTGS2), immune imbalance (IL-8, IL-Iss, CCL3), and active atherosclerosis (DUSP-1, OSM, ATF3). | 25463097 |
| Rheumatoid Arthritis, Inflammation | Altered Intercellular Communication | Altered lipidome and antioxidative activity of small, dense HDL in normolipidemic rheumatoid arthritis: relevance of inflammation. | 25463101 |
| Refractory anemias, Inflammation, Rheumatoid Arthritis | Altered Intercellular Communication | Such activities are enriched in small, dense HDL and can be compromised under conditions of chronic inflammation like rheumatoid arthritis (RA). | 25463101 |
| Refractory anemias, Inflammation, Hemophilia A | Altered Intercellular Communication | These data revealed that (i) despite normolipidemic state, the lipidome of small, dense HDL was altered in RA and (ii) high levels of inflammation can be responsible for the functional deficiency of small, dense HDL in RA. | 25463101 |
| Inflammation, Thrombosis | Altered Intercellular Communication | At the light of a literature review, we discussed our surgical strategy and the inflammation of the aortic wall as local factor of thrombosis that has never been previously described. | 25463334 |
| Inflammation | Altered Intercellular Communication | Since inflammation is very limited in these wounds reduced numbers or even absence of immune cells might be responsible for scarless foetal wound healing. | 25463905 |
| Inflammation | Altered Intercellular Communication | Systemic oxidative stress and inflammation levels were also increased in both patient groups compared to controls (p<0.005, both). | 25464271 |
| Inflammation, Cyclophosphamide/Vincristine/Dacarbazine Regimen, Cardiovascular Diseases | Altered Intercellular Communication | Major adverse cardiovascular events (MACEs) in patients with or without cardiovascular disease (CVD) are greatly affected by various factors associated with metabolism and inflammation. | 25464435 |
| Respiratory Syncytial Virus Infections, Pneumonitis | Altered Intercellular Communication | Importantly, the interaction of PD-1 with its ligand PD-L1 is vital to restrict the pro-inflammatory activities of lung effector T cells in situ, thereby inhibiting the development of excessive pulmonary inflammation and injury during RSV infection. | 25465101 |
| Inflammation, Nerve Degeneration | Altered Intercellular Communication | Inflammation may reduce hippocampal volume by blocking neurogenesis and promoting neurodegeneration. | 25465168 |
| Post-Traumatic Stress Disorder, Inflammation | Altered Intercellular Communication | Posttraumatic stress disorder (PTSD) has been linked with both elevated inflammation and reduced hippocampal volume. | 25465168 |
| Inflammation, hepcidin, Anemia | Altered Intercellular Communication | Hepatic hepcidin-25 production is stimulated by systemic inflammation, and it interferes with the body's utilization of iron, leading to anemia. | 25465232 |
| Fibrosis Assessment, Thyroiditis, Haiti | Altered Intercellular Communication | IgG4-related HT is a new subtype characterized by thyroid inflammation rich in IgG4-positive plasma cells and marked fibrosis. | 25465611 |
| Inflammation, Triple-Negative Breast Cancer Finding, Neoplasms | Altered Intercellular Communication | Gene expression of cancer-adjacent tissues shows that triple-negative (Claudin-low or basal-like) tumors exhibit increased expression of genes involved in inflammation and immune response. | 25465802 |
| Chemoradiotherapy, Inflammation, Non-Small Cell Lung Carcinoma, Esophagitis | Altered Intercellular Communication | We sought to investigate whether three serum miRNAs related to immunity or inflammation were associated with esophagitis induced by chemoradiation therapy (CRT) for non-small cell lung cancer (NSCLC). | 25466375 |
| Pharyngitis, Abdominal Pain | Altered Intercellular Communication | The dominant symptoms at the department were abdominal pain and throat inflammation. | 25466421 |
| Inflammation, Acute Disease | Altered Intercellular Communication | An acute disease is regularly associated with inflammation, decreased food intake, and low physical activity; the consequence is loss of muscle mass. | 25466662 |
| Atrial Fibrillation, Inflammation, Atrial Fibrillation by ECG Finding, Obesity | Altered Intercellular Communication | Also, given the strong relationship between atrial fibrillation (AF), obesity and inflammation, the purpose of this study was to investigate the association of non-valvular AF with epicardial and periatrial fat. | 25466809 |
| Inflammation, Corneal Opacity | Altered Intercellular Communication | Examination of the left eye revealed multiple corneal opacities, deep stromal neovascularization and anterior chamber inflammation. | 25467290 |
| Arthritis, Lupus Erythematosus, Systemic | Altered Intercellular Communication | Even SLE patients without clinical signs of joint inflammation demonstrated US abnormalities. | 25467390 |
| Kidney Failure, Chronic, Renal function, Albuminuria | Altered Intercellular Communication | Inflammation-related microvasculr disease, albuminuria, and rapid deterioration of renal function can accelerate the development of end-stage renal disease (ESRD). | 25468738 |
| Kidney Failure, Chronic, Inflammation, Fracture, Disease | Altered Intercellular Communication | The role of hip fracture (HFr), a disorder that involves inflammation, in the development of ESRD has not been fully investigated. | 25468738 |
| Kidney Failure, Chronic, Inflammation, Microvascular Angina, Chronic disease | Altered Intercellular Communication | This study is the first to report that HFr, in combination with underlying osteoporosis-related chronic illness, microvascular disease and chronic inflammation, is associated with an increased risk of ESRD, particularly among relatively younger people. | 25468738 |
| Inflammation, Anastomotic Leak, Abdominal Abscess | Altered Intercellular Communication | Amplification of inflammation and angiogenesis might be one of the mechanisms responsible for the higher recurrence rate observed in patients with anastomotic leakage or intra-abdominal abscess. | 25468742 |
| Inflammation, Abscess of lacrimal gland, Dacryoadenitis | Altered Intercellular Communication | Dacryoadenitis, a condition defined as inflammation of the lacrimal gland, has many etiologies; rarely is it associated with a lacrimal gland abscess. | 25469005 |
| Tuberculosis, Leishmaniasis, Granulomatous inflammation, Aspergillosis, Acute suppurative inflammation | Altered Intercellular Communication | In this study, there were 13 cases of tuberculosis, 25 cases of granulomatous inflammation, 10 cases of acute suppurative inflammation, and one case each of leishmaniasis, aspergillosis and extramedullary hematopoiesis. | 25469450 |
| Inflammation, Obesity, Abdominal, Impaired cognition | Altered Intercellular Communication | Abdominal obesity contributes to neurocognitive impairment in HIV-infected patients with increased inflammation and immune activation. | 25469522 |
| Inflammation, Obesity, Abdominal | Altered Intercellular Communication | Abdominal obesity, inflammation, and central nervous system immune activation are potential therapeutic targets for NCI in HIV-positive patients. | 25469522 |
| Inflammation, Nasal Polyps, Chronic sinusitis | Altered Intercellular Communication | Although chronic rhinosinusitis with nasal polyps (CRSwNP) is characterized by Th2 inflammation, the mechanism underlying the onset and amplification of this inflammation has not been fully elucidated. | 25469646 |
| Inflammation, Myeloid | Altered Intercellular Communication | Myeloid DCs thus may indirectly contribute to the inflammation observed in CRSwNP. | 25469646 |
| Inflammation | Altered Intercellular Communication | These results support growing evidence showing that inflammation is associated with cancer-related symptoms, and they suggest that racial/ethnic factors contribute to this association. | 25469832 |
| Refractory anemias, Inflammation | Altered Intercellular Communication | Systemic inflammation is proposed to play a fundamental role in the altered lipid metabolism associated with RA; however, the underlying mechanisms are unknown. | 25470338 |
| Inflammation, Malaria, Tuberculosis | Altered Intercellular Communication | Based on demonstrated roles in up-regulating innate immunity, decreasing inflammation, and reducing the severity of disease in illnesses such as tuberculosis and influenza, we hypothesized that poor vitamin D status would be associated with severe malaria. | 25470777 |
| Inflammation, Malignant Neoplasms | Altered Intercellular Communication | As many mesothelial cells are simultaneously exposed to asbestos fibers and to asbestos-induced inflammation, it may be possible that more than one cell undergoes malignant transformation during the process that gives rise to MM, and result in a polyclonal malignancy. | 25471750 |
| Inflammation | Altered Intercellular Communication | Inflammation could be an underlying confounding factor explaining the increased mortality in these patients. | 25472577 |
| MCC protocol, Inflammation | Altered Intercellular Communication | Evidence is emerging that inflammation and immune response play a role in the pathogenesis of CCM. | 25472749 |
| Inflammation, Colorectal Carcinoma | Altered Intercellular Communication | Chronic inflammation is a key feature of colorectal cancer (CRC), meaning that inflammatory biomarkers may be useful for its diagnosis. | 25472811 |
| vascular inflammations, Aortic Aneurysm, Abdominal | Altered Intercellular Communication | ACE inhibitors potently reduce vascular inflammation, results of an open proof-of-concept study in the abdominal aortic aneurysm. | 25474105 |
| APP gene, vascular inflammations | Altered Intercellular Communication | ACE inhibition quenches multiple aspects of vascular inflammation in AAA. | 25474105 |
| Inflammation, Asthma, Wheezing | Altered Intercellular Communication | To assess whether exhaled biomarkers, expression of inflammation genes, and early lung function measurements can improve a reliable asthma prediction in preschool wheezing children. | 25474185 |
| Inflammation, Asthma | Altered Intercellular Communication | Adding information on exhaled VOCs and possibly expression of inflammation genes to the API significantly improves an accurate asthma diagnosis in preschool children. | 25474185 |
| Inflammation, Atherosclerosis, GDC AJCC Clinical Stage Terminology | Altered Intercellular Communication | A considerable amount of evidence indicates that inflammation is responsible for the development of atherosclerosis in patients with ACS. | 25474223 |
| Inflammation, GDC AJCC Clinical Stage Terminology | Altered Intercellular Communication | These findings demonstrate for the first time that sAxl does have a role in ACS, presumably connected to the inflammation. | 25474223 |
| Airway structure, ARCN1 gene | Altered Intercellular Communication | Supplementing defect in club cell secretory protein attenuates airway inflammation in COPD. | 25474370 |
| Refractory anemias, Rheumatoid Arthritis, Inflammation | Altered Intercellular Communication | Citrullination of proteins is well described in rheumatoid arthritis (RA), and hypercitrullination of proteins may be related to inflammation in general. | 25475141 |
| Inflammation, CRNKL1 wt Allele, Liver Cirrhosis | Altered Intercellular Communication | Whereas expression of iron-regulatory genes was markedly down-regulated, genes related to endoplasmic reticulum stress, apoptosis, and inflammation were up-regulated in ACLF patients, compared to patients with cirrhosis. | 25475192 |
| Inflammation, Squamous cell carcinoma, SERPINB3 wt Allele | Altered Intercellular Communication | An inflammation, which is innate in the carcinogenesis of oral squamous cell carcinoma (OSCC), frequently complicates the image analysis because of the limitations of (18)F-FDG and maximum standardized uptake values (SUV(max)). | 25476535 |
| Inflammation, Neoplasms | Altered Intercellular Communication | The whole tumor dissected from surgery was measured and sectioned for pathologic analysis of tumor inflammation grade and Ki-67 labeling index. | 25476535 |
| Inflammation, Inflammatory Myofibroblastic Tumor, Neoplasms | Altered Intercellular Communication | The SUV(max )ratio of (18)F-FDG to (18)F-FAMT was higher in inflammatory tumors (P < 0.05) whereas the corresponding value in tumors with a low inflammation grade was kept low. | 25476535 |
| Inflammation, Appendicitis, CTCAE | Altered Intercellular Communication | Patients were classified based on final histopathological findings into the groups: no appendiceal inflammation, non-perforated appendicitis and perforated appendicitis. | 25476715 |
| Inflammation, Appendicitis, CTCAE, Appendicitis Perforated, CTCAE | Altered Intercellular Communication | Of 493 analysed patients, 125 (25%) had no appendiceal inflammation, 312 (64%) had non-perforated appendicitis and 56 (11%) had perforated appendicitis. | 25476715 |
| Inflammation, Hyperbilirubinemia, Appendicitis, CTCAE | Altered Intercellular Communication | Hyperbilirubinaemia is present in acute appendicitis but has a low diagnostic accuracy in discriminating between any appendicitis versus no appendiceal inflammation and perforated versus non-perforated appendicitis and is, therefore, of limited value in clinical routine. | 25476715 |
| Inflammation, Dental caries | Altered Intercellular Communication | Cytokines are associated with levels of inflammation and are involved in caries, pulpal, and periapical tissue destruction. | 25476976 |
| Inflammation, Obesity | Altered Intercellular Communication | Human adenovirus type 36 (Ad36) as an obesity agent induces adiposity by increasing glucose uptake and promoting chronic inflammation in fat tissues; in contrast, exercise reduces total body fat and inflammation. | 25479564 |
| Inflammation, Weight decreased | Altered Intercellular Communication | Similarly, Ad36-infected mice were resistant to weight loss and exhibited chronic inflammation of their adipose tissues despite frequent exercise. | 25479564 |
| ARCN1 gene, Inflammation, Choline Dehydrogenase, Mitochondrial | Altered Intercellular Communication | Participants were divided into 5 groups: 1) no COPD, no CHD; 2) COPD without inflammation, no CHD; 3) COPD with inflammation, no CHD; 4) CHD only, and 5) CHD + COPD. | 25480156 |
| ARCN1 gene, Inflammation | Altered Intercellular Communication | A novel "inflammatory" COPD designation included those with COPD and clinical evidence of inflammation (i.e., CRP >=95.24 nmol/L). | 25480156 |
| ARCN1 gene, Inflammation, Choline Dehydrogenase, Mitochondrial | Altered Intercellular Communication | For total mortality, the risk was significant for the four groups: the non-inflammatory COPD group; the COPD with inflammation group, the CHD group, and the COPD + CHD group. | 25480156 |
| ARCN1 gene, Inflammation, GDC Comorbidity Terminology, Choline Dehydrogenase, Mitochondrial | Altered Intercellular Communication | Moreover, given that COPD results from inflammation, the systemic inflammation associated with COPD may have worsened comorbid conditions and may have lead to the increased total mortality found in the COPD with inflammation and COPD + CHD groups which requires further investigation. | 25480156 |
| Alzheimers Disease", Inflammation, Data types - Address | Altered Intercellular Communication | The complex pathogenesis of Alzheimer's disease (AD) involves multiple contributing factors, including amyloid b (Ab) peptide accumulation, inflammation and oxidative stress. | 25481013 |
| Rheumatoid Arthritis, Inflammation | Altered Intercellular Communication | [Expression of cadherin-11 in rheumatoid arthritis synovium and its correlation with inflammation]. | 25481189 |
| Refractory anemias, Inflammation, Rheumatoid Arthritis | Altered Intercellular Communication | To explore the pattern of cadherin-11 expression and its relationship with synovial inflammation in rheumatoid arthritis (RA), and study the regulatory effects of cytokines on cadherin-11 expression on RA fibroblast-like synoviocytes (RAFLS). | 25481189 |
| Synovitis | Altered Intercellular Communication | After HE staining, synovitis score was determined according to Rooney's inflammation score system. | 25481189 |
| Refractory anemias | Altered Intercellular Communication | The expression of cadherin-11 in RA synovium was semi-quantified by immunohistochemical staining, and its correlations with Rooney's inflammation score and systematic inflammatory markers were analyzed statistically. | 25481189 |
| Pain Distress Question, Inflammation | Altered Intercellular Communication | No pain or any other signs of inflammation were observed. | 25481274 |
| Inflammation | Altered Intercellular Communication | We also showed that behavioural factors contributed the most to SES differences in inflammation. | 25482420 |
| Inflammation, GDC Disease Response Terminology | Altered Intercellular Communication | Inflammation plays a considerable role in the pathogenesis of T2DM and DR. | 25483847 |
| Inflammation | Altered Intercellular Communication | There is a question of closing tissue defects after the elimination period of acute inflammation. | 25484157 |
| Inflammation, Blood Vessel, Hypoxemia, Pre-Eclampsia | Altered Intercellular Communication | Faulty placentation manifests in the mother as preeclampsia with vascular damage, enhanced systemic inflammation, and insulin resistance; in the placenta as oxygen and nutrient transfer restriction and oxidative stress; and in the fetus as growth restriction and progressive hypoxemia. | 25485869 |
| Inflammation, Gallbladder | Altered Intercellular Communication | Percutaneous cholecystostomy (PC) is a safe treatment for acute inflammation of the gall bladder. | 25487543 |
| Degenerative polyarthritis, Inflammation | Altered Intercellular Communication | It is unknown whether joint inflammation precedes other articular tissue damage in osteoarthritis. | 25488799 |
| Communicable Diseases, Inflammation, Infection | Altered Intercellular Communication | Finely tuned to respond quickly to infections, neutrophils have amazing abilities to migrate fast and efficiently towards sites of infection and inflammation. | 25489947 |
| Inflammation, Diabetes Mellitus | Altered Intercellular Communication | The risk of incident type 2 diabetes in a Korean metabolically healthy obese population: the role of systemic inflammation. | 25490279 |
| Inflammation, Units Of Measure - Siemens, Diabetes Mellitus | Altered Intercellular Communication | This study sought to investigate whether the metabolically healthy obese (MHO) phenotype is associated with an increased risk of incident type 2 diabetes in a Korean population and, if so, whether systemic inflammation affects this risk in MHO individuals. | 25490279 |
| Inflammation, Units Of Measure - Siemens | Altered Intercellular Communication | However, the risk of the MHO group varied according to the degree of systemic inflammation. | 25490279 |
| Inflammation, Diabetes Mellitus, Non-Insulin-Dependent | Altered Intercellular Communication | Compared with the MHNO/low systemic inflammation group, the risk of type 2 diabetes in the MHO/low systemic inflammation group was not significantly elevated (multivariate-adjusted HR, 1.61; 95% CI, 0.77-3.34). | 25490279 |
| Inflammation, Diabetes Mellitus, Non-Insulin-Dependent | Altered Intercellular Communication | However, the MHO/high systemic inflammation group had an elevated risk of incident type 2 diabetes (multivariate-adjusted HR, 3.73; 95% CI 2.36-5.88). | 25490279 |
| Autoimmune Diseases, Idiopathic Inflammatory Myopathies, Myositis | Altered Intercellular Communication | Idiopathic inflammatory myopathies (IIM) are a rare group of autoimmune diseases characterized by muscle inflammation. | 25490616 |
| Inflammation, Primary malignant neoplasm, Neoplasm Metastasis, Laryngeal Squamous Cell Carcinoma | Altered Intercellular Communication | Inflammation and cancer: role of annexin A1 and FPR2/ALX in proliferation and metastasis in human laryngeal squamous cell carcinoma. | 25490767 |
| Inflammation, Fibrosis Assessment, Fatty degeneration | Altered Intercellular Communication | After surgery, fibrosis, steatosis, lobular inflammation, portal inflammation, and ballooning in the background liver were assessed. | 25490872 |
| ARCN1 gene, Inflammation, Chronic Obstructive Airway Disease | Altered Intercellular Communication | Chronic obstructive pulmonary disease (COPD) is a common health problem and it is associated with oxidant/antioxidant imbalance and systemic inflammation. | 25491624 |
| Communicable Diseases, Inflammation | Altered Intercellular Communication | HP+ GC appeared to show a higher proliferative capacity, more extensive spread, and more rapid progression, and inflammation associated with HP infection was suggested to be involved in the proliferation of this type of GC. | 25491775 |
| Communicable Diseases, Helicobacter pylori, Inflammation, Malignant neoplasm of stomach | Altered Intercellular Communication | Stomach cancer can occur during chronic inflammation from Helicobacter pylori (HP) infection, and its occurrence can be suppressed by eradication of HP. | 25491907 |
| Inflammation, MS gene | Altered Intercellular Communication | Astroglial PGC-1alpha increases mitochondrial antioxidant capacity and suppresses inflammation: implications for multiple sclerosis. | 25492529 |
| Inflammation, Nerve Degeneration | Altered Intercellular Communication | Our findings suggest that increased astrocytic PGC-1a in active MS lesions might initially function as an endogenous protective mechanism to dampen oxidative damage and inflammation thereby reducing neurodegeneration. | 25492529 |
| Prostate carcinoma, Structure of posterior cerebral artery | Altered Intercellular Communication | Long-term exposure to persistent pollutants with hormonal properties (endocrine-disrupting chemicals; EDCs) may contribute to the risk of prostate cancer (PCa). | 25493337 |
| Inflammation | Altered Intercellular Communication | Pulmonary function, physical fitness (6MWD) and asthmatic inflammation (FENO) were measured at T0 and T1. | 25494552 |
| Inflammation, Metabolic Syndrome X | Altered Intercellular Communication | Association of altered hemorheology with oxidative stress and inflammation in metabolic syndrome. | 25494675 |
| Inflammation, ETV3 wt Allele | Altered Intercellular Communication | The objective of the study was to find out if the altered hemorheology shown in MetS in our previous study is associated with chronic inflammation and oxidative stress in the same subjects. | 25494675 |
| Inflammation | Altered Intercellular Communication | We found a significant association of altered hemorheology with chronic inflammation and oxidative stress in MetS. | 25494675 |
| Inflammation, ETV3 wt Allele | Altered Intercellular Communication | Alterations of hemorheology in MetS are probably due to the effect of chronic inflammation and oxidative stress. | 25494675 |
| Inflammation | Altered Intercellular Communication | The negative effects of chronic inflammation and oxidative stress on the cardiovascular system could be due to the resulting altered hemorheology. | 25494675 |
| Thrombosis, Postthrombotic Syndrome | Altered Intercellular Communication | Inflammation markers and their trajectories after deep vein thrombosis in relation to risk of post-thrombotic syndrome. | 25495610 |
| Metabolic Syndrome X | Altered Intercellular Communication | These results provide new evidence that the relatively rarely-studied active hormonal form of vitamin D, 1,25(OH)2D, is associated with metabolic syndrome and its components, and confirm prior findings for 25(OH)D. The finding that 1,25(OH)2D is related to high-density lipoprotein, while 25(OH)D is not, suggests that there may be an independent mechanism of action for 1,25(OH)2D in relation to metabolic dysregulation. | 25496802 |
| Inflammation, Papillon-Lefevre Disease | Altered Intercellular Communication | Results showed that periodontal inflammation of PLS peaked at teenage years, but declined with time. | 25497043 |
| Inflammation, Traumatic injury, Multiple Trauma | Altered Intercellular Communication | During sterile inflammation, polytrauma and burn trauma patients initially present with high serum concentrations of myeloid-related proteins (MRPs). | 25497086 |
| Inflammation, Infection | Altered Intercellular Communication | Our data therefore indicate that alarmin-triggered phagocyte tolerance represents a regulatory mechanism for the susceptibility of neonates during systemic infections and sterile inflammation. | 25497086 |
| Inflammation | Altered Intercellular Communication | Moreover, cardiac inflammation did not influence Nampt expression, and Nampt concentrations did not modulate cardiac inflammation in DCMi. | 25498756 |
| THANATOPHORIC DYSPLASIA, TYPE I (disorder), Polyradiculoneuropathy, Chronic Inflammatory Demyelinating | Altered Intercellular Communication | This report confirms and expands the spectrum of inflammatory demyelinating conditions associated with IVF and suggests possible hormonal influence in the development of TD. | 25499758 |
| Multiple Organ Failure, Pancreatitis | Altered Intercellular Communication | Cytokine coadministration resulted in higher pancreatic and lung inflammation than caerulein alone, but only triolein coadministration caused peripancreatic fat stranding, higher cytokines, UFAs, multisystem organ failure (MSOF) and mortality in 97% animals, which were prevented by orlistat. | 25500204 |
| Inflammation, Lipolysis | Altered Intercellular Communication | However, UFAs generated via peripancreatic fat lipolysis causes worse inflammation and MSOF, converting mild AP to SAP. | 25500204 |
| Central Nervous System | Altered Intercellular Communication | Inflammation-induced alterations in central nervous system (CNS) metabolism have focused on glutamate. | 25500218 |
| Inflammation, Depression, CTCAE, Disease | Altered Intercellular Communication | Increased glutamate has also been found in depression, a disorder associated with increased inflammation. | 25500218 |
| Autoimmune Diseases, Tumor necrosis, Inflammation | Altered Intercellular Communication | The tumor necrosis factor receptor-associated factor 1/complement C5 (TRAF1/C5) genes have been suggested as two candidate genes for conferring susceptibility to autoimmunity and inflammation. | 25500258 |
| Inflammation, Swelling, Obstruction | Altered Intercellular Communication | chronic swelling or obstruction and inflammation of the salivary duct. | 25500629 |
| Inflammation, Necrosis | Altered Intercellular Communication | Nongranulomatous inflammation with fibrinoid necrosis of medium-sized vessels occurred equally in both groups (>90%). | 25500710 |
| Myositis | Altered Intercellular Communication | Visual grading of the bone scans had a sensitivity and specificity of 74 and 90.9 %, respectively, for the assessment of muscle inflammation. | 25501462 |
| Parkinson Disease, Inflammation, Parkinsonian Disorders | Altered Intercellular Communication | Parkinson's disease and atypical forms of parkinsonism occur mainly in the elderly, with oxidative stress and inflammation in afflicted cells. | 25501556 |
| Inflammation | Altered Intercellular Communication | If the patient has undergone previous intra-abdominal operations or chronic inflammation of the pancreas is found, special care of the spleen during the operation is necessary. | 25501876 |
| Inflammation | Altered Intercellular Communication | CCL18 is a chemokine that is primarily expressed in monocytes, macrophages and immature dendritic cells and plays a crucial role in immune and inflammation responses. | 25502147 |
| Inflammation | Altered Intercellular Communication | These results suggest that the effect of losartan on insulin resistance is associated with the reduction of oxidative stress and inflammation in patients with type 2 DKD as well as the activation of insulin signal pathway in insulin-resistance 3T3-L1 adipocytes through modulation of PI3K pathway. | 25502581 |
| palladium | Altered Intercellular Communication | The lack of modulations of bilateral arm coordination suggests that additional neurotransmitters may also be involved in arm swing changes in PD. | 25502948 |
| Communicable Diseases, Inflammation, Traumatic injury | Altered Intercellular Communication | Increased local skin temperature is a classic sign of wound infection, repetitive trauma, and deep inflammation. | 25502971 |
| Inflammation, Prostate carcinoma | Altered Intercellular Communication | Comparison of prostate cancer gene 3 score, prostate health index and percentage free prostate-specific antigen for differentiating histological inflammation from prostate cancer and other non-neoplastic alterations of the prostate at initial biopsy. | 25503144 |
| Stomach Carcinoma | Altered Intercellular Communication | Clinical significance of an inflammation-based prognostic system for gastric cancer patients with a preoperative normal serum level of carcinoembryonic antigen. | 25503152 |
| Primary malignant neoplasm | Altered Intercellular Communication | On the other hand, the GPS has been established as a valuable inflammation-based prognostic system for cancer patients. | 25503152 |
| Inflammation, Colorectal Carcinoma | Altered Intercellular Communication | The molecular mechanism underlying the development of colorectal cancer (CRC) is not yet fully-understood, but there is evidence that inflammation plays a key role. | 25503158 |
| Inflammation | Altered Intercellular Communication | Radiation recall refers to chemotherapy-triggered inflammation in healthy areas previously exposed to irradiation. | 25503169 |
| Inflammation | Altered Intercellular Communication | MMP-8 could play an important role in the inflammation processes during the development of periapical lesions. | 25503342 |
| Hemorrhagic, Inflammation, Endothelial dysfunction, Ischemic stroke | Altered Intercellular Communication | Our results suggest that NURR1 upregulation by r-tPA during ischemic stroke is associated with endothelial dysfunction and inflammation and the enhancement of hemorrhagic complications associated to thrombolysis. | 25503547 |
| glycation, Inflammation, Chronic disease | Altered Intercellular Communication | A receptor for advanced glycation end products (RAGE) and its ligand high mobility group box 1 (HMGB1) protein has been linked to several chronic diseases, and acts as a trigger for inflammation signaling. | 25503556 |
| Malaria, Falciparum, Communicable Diseases, Inflammation | Altered Intercellular Communication | Our findings underscore the complex role of inflammation during infection with P. falciparum, and suggest a potential pathogenic role for IL-8 and IP-10. | 25503583 |
| Cessation of life, Hepatic inflammation | Altered Intercellular Communication | Waterborne exposure of zebrafish in cage water containing AA (300 ppm) resulted in acute death within 26 h along with elevation of body weight, blood glucose, triglyceride, and hepatic inflammation. | 25503949 |
| Herpes, Angiolymphoid hyperplasia, Hyponatremia | Altered Intercellular Communication | We hypothesize that non-osmotic release of plasma antidiuretic hormone is a cause of hyponatraemia in human herpes virus-8-associated multicentric Castleman's disease and that relapsing and remitting hyponatraemia could be correlated with plasma human herpes virus-8 viral load. | 25504830 |
| Refractory anemias, Inflammation, Rheumatoid Arthritis, Atherosclerosis | Altered Intercellular Communication | Systemic inflammation and insulin resistance (IR) are linked, yet the determinants of IR and its impact on atherosclerosis in rheumatoid arthritis (RA) are incompletely understood. | 25504899 |
| Inflammation, Malnutrition, Anemia | Altered Intercellular Communication | A cohort of 199 fit hemodialysis patients free of overt inflammation and malnutrition were treated for anemia with parenteral iron-sucrose and an erythropoesis-stimulating agent (darbepoetin), in keeping with current clinical guidelines. | 25506921 |
| Gastrointestinal inflammation | Altered Intercellular Communication | Calprotectin is a cytoplasmatic protein of neutrophilic granulocytes and it is an established marker for the assessment of localized intestinal inflammation. | 25509200 |
| Inflammation, Malignant Neoplasms | Altered Intercellular Communication | Chronic inflammation and immunosuppressive treatment are risk factors for epithelial and lymphoid malignancies. | 25509562 |
| Inflammation, Chronic heart failure, Ventricular Dysfunction | Altered Intercellular Communication | [Biomarkers of iron metabolism and inflammation in patients with chronic heart failure and various types of left ventricular dysfunction]. | 25510083 |
| Inflammation, Perforation (observation) | Altered Intercellular Communication | Therefore a formal term from the moment of perforation can not be the index of degree of inflammation (bacterial contamination) of peritoneum. | 25510091 |
| Weight Gain, Inflammation | Altered Intercellular Communication | Inflammation and weight gain in reproductive-aged women. | 25510294 |
| Inflammation, Synovitis, Refractory anemias, Edema of bone marrow, Rheumatoid Arthritis, Tenosynovitis | Altered Intercellular Communication | Magnetic resonance imaging (MRI) is a sensitive method to detect inflammation in rheumatoid arthritis (RA), visualizing synovitis, bone marrow edema, and tenosynovitis. | 25510520 |
| Inflammation | Altered Intercellular Communication | Vitamin D is associated with skeletal muscle physiology and function and may play a role in intramuscular inflammation, possibly via the vitamin D receptor (VDR). | 25510525 |
| Inflammation, Actinomycosis | Altered Intercellular Communication | Endometrial/endocervical specimens showed marked chronic inflammation with sulfur granules, with a colony of filamentous organisms consistent with Actinomyces infection. | 25510706 |
| Inflammation, Intracranial Aneurysm, Rupture | Altered Intercellular Communication | Inflammation plays a key role in formation and rupture of intracranial aneurysms. | 25510828 |
| vascular inflammations, Intracranial Aneurysm | Altered Intercellular Communication | Because hepatocyte growth factor (HGF) protects against vascular inflammation, we sought to assess the role of endogenous HGF in the pathogenesis of intracranial aneurysms. | 25510828 |
| Inflammation, Aneurysm, Ruptured | Altered Intercellular Communication | HGF signaling through c-Met may decrease inflammation in endothelial cells and protect against intracranial aneurysm rupture. | 25510828 |
| Hyperglycemia, Inflammation | Altered Intercellular Communication | In PBMC of T2DM without glycemic target achievement, there is an activation of the UPR and of the ER apoptosis, which may be related to the chronic exposure to hyperglycemia, to the augmented inflammation, and to the augmented oxidative stress, without a corresponding Nrf2/ARE defense activation. | 25511473 |
| Inflammation, Immune-mediated, Nerve Degeneration | Altered Intercellular Communication | Multiple Sclerosis (MS) is an immune-mediated disease of the Central Nervous System with two major underlying etiopathogenic processes: inflammation and neurodegeneration. | 25512202 |
| Inflammation, HIV, GDC Comorbidity Terminology | Altered Intercellular Communication | Elite controllers spontaneously suppress human immunodeficiency virus (HIV) viremia but also demonstrate chronic inflammation that may increase risk of comorbid conditions. | 25512624 |
| Metabolic Syndrome X | Altered Intercellular Communication | Walk-run training improves the anti-inflammation properties of high-density lipoprotein in patients with metabolic syndrome. | 25514103 |
| ETV3 wt Allele | Altered Intercellular Communication | This study was designed to investigate whether walk/run training without any specific diet could enhance anti-inflammation capacity of HDL from MetS patients. | 25514103 |
| ETV3 wt Allele | Altered Intercellular Communication | The anti-inflammation capacities of HDL3 (HDL subfractions) from MetS patients with or without exercise were investigated by co-incubating with TNF- a-injured endothelial cells in vitro. | 25514103 |
| ETV3 wt Allele | Altered Intercellular Communication | Walk/run training leads to a significant improvement in HDL anti-inflammation capacity in subjects with MetS without restricted diet, the mechanism underlying which at least partially is due to increased PON1 activity in HDL, NO production, and eNOS expression in endothelial cells. | 25514103 |
| eosinophil, Asthma | Altered Intercellular Communication | These findings support the requirement of CLC3 in the activation and migration of human blood eosinophils and may provide a potential novel therapeutic target to regulate eosinophil hyperactivity in allergic airway inflammation in asthma. | 25514499 |
| ACSM3 gene, Subarachnoid Hemorrhage, Aneurysmal, Hypothalamo-Hypophyseal System | Altered Intercellular Communication | Impaired systemic hormonal activity caused by hypothalamic and pituitary injury may contribute to neuropsychologic disturbances and poor quality of life after aneurysmal subarachnoid hemorrhage (SAH). | 25514615 |
| Granulomatous inflammation | Altered Intercellular Communication | Granulomatous inflammation with central caseous necrosis surrounded by edematous brain with reactive gliosis and acid-fast bacilli were revealed on histopathologic analysis. | 25515023 |
| Inflammation, Specimen Type - Fistula | Altered Intercellular Communication | Immunohistochemical staining revealed decreases in membrane E-cadherin and b-catenin and a significant increase in the cytoplasmic fraction, depending on the severity of inflammation in the fistula tissue. | 25515126 |
| Inflammation, Pancreatic carcinoma | Altered Intercellular Communication | However, the possible relationship between diet-related inflammation and the risk of pancreatic cancer has not yet been investigated. | 25515552 |
| Inflammation, Neoplasms | Altered Intercellular Communication | The neutrophil-to-lymphocyte ratio (NLR), a marker of host inflammation, has been associated with poor outcome in several solid tumors. | 25515657 |
| Malignant neoplasm of esophagus | Altered Intercellular Communication | The inflammation-based modified Glasgow prognostic score (mGPS) has been shown to be a prognostic factor for esophageal cancer, but its changes in relation to neoadjuvant chemotherapy (NAC) have never been discussed. | 25515972 |
| Inflammation | Altered Intercellular Communication | The findings suggest that coagulation leads to functional decline and mortality s that inflammation does not explain. | 25516032 |
| Degenerative disorder, Neoplasms | Altered Intercellular Communication | These concepts are relevant to issues in modern human longevity, including inflammation-induced neoplasia and degenerative diseases of the elderly, which are a legacy of human evolution. | 25516618 |
| Degenerative disorder, Neoplasms | Altered Intercellular Communication | The hypothesis that we present provides new bases for modern medical problems, such as inflammation-induced neoplasia and degenerative diseases of the elderly. | 25516618 |
| Inflammation, Acute myocardial infarction | Altered Intercellular Communication | Inflammation in the setting of acute myocardial infarction (MI) has been linked to risk stratification; however, the release kinetics of inflammatory biomarkers in patients with acute MI has been difficult to establish. | 25516775 |
| Airway Obstruction, Pulmonary Emphysema, Bronchitis | Altered Intercellular Communication | Among others, the identified genes are also involved in emphysema, airway obstruction, and bronchial inflammation. | 25517131 |
| Inflammation, Medial degeneration | Altered Intercellular Communication | We previously showed that the metabolically active areas displayed adventitial inflammation, medial degeneration and molecular alterations prefacing wall rupture. | 25517227 |
| Inflammation, Acute appendicitis NOS (disorder) | Altered Intercellular Communication | Correlation between the serum and tissue levels of oxidative stress markers and the extent of inflammation in acute appendicitis. | 25518019 |
| IL13 gene, Inflammatory disease of mucous membrane | Altered Intercellular Communication | Allergic rhinitis is a disease that affects the upper airways and causes inflammation of the nasal mucosa and it is mediated by IgE antibodies produced after sensitization to environmental allergens. | 25518031 |
| Ulcerative Colitis | Altered Intercellular Communication | Sixty-two patients with ulcerative colitis underwent colonoscopy for classification of mucosal inflammation [Mayo endoscopic subscore]. | 25518057 |
| Vasculitis | Altered Intercellular Communication | Its anti-inflammation effects suppress vascular wall inflammation of KD at acute phase. | 25518411 |
| Inflammation | Altered Intercellular Communication | It was found that the number of lymphocytes and neutrophils located in the lamina and intraepithelial increases, which is associated with the degree of inflammation. | 25518455 |
| Inflammation | Altered Intercellular Communication | Intensity of leukocyte infiltration is directly correlated with the increased prevalence of inflammation. | 25518455 |
| Inflammation | Altered Intercellular Communication | Cellular composition of the infiltrate is an objective characteristic of chronic inflammation in the gastric mucosa. | 25518455 |
| Inflammation, senile, Diabetes Mellitus, Non-Insulin-Dependent | Altered Intercellular Communication | Problems with insulin secretion lead to oxidative stress, chronic inflammation, and type II diabetes, which can be regarded as one of the forms of senile phenoptosis. | 25519059 |
| Inflammation, Neoplasms, Colon diverticulum anatomic structure, Hemorrhoids, CTCAE 5.0, Colonic Polyps | Altered Intercellular Communication | Data collected were patient demographic and significant colonoscopy findings such as the presence of hemorrhoids, colonic polyps, colonic diverticula, inflammation, and tumor mass. | 25520108 |
| Crohn Disease, Inflammation, Ulcerative Colitis, Cryptitis | Altered Intercellular Communication | CLE findings in patients with Crohn's disease, showed significantly more discontinuous inflammation (87.5 % vs. 5.1 %), focal cryptitis (75.0 % vs. 12.8 %), and discontinuous crypt architectural abnormality (87.5 % vs. 10.3 %) than in ulcerative colitis (P < 0.0001). | 25521573 |
| methyldopa, Inflammation, Atrophic | Altered Intercellular Communication | Whether this physiologic deviation that occurs in AMD is related to atrophy, inflammation, or changes in autoregulatory factors or growth factors remains to be determined. | 25521616 |
| Intestinal metaplasia, Inflammation, Atrophic | Altered Intercellular Communication | Histological changes, including chronic inflammation, activity, atrophy, and intestinal metaplasia, were evaluated using the updated Sydney system. | 25521735 |
| Inflammation | Altered Intercellular Communication | Chronic inflammation scores were improved after eradication at both the lesser (mean scores +- SD: before eradication, 2.9+-0.5; 1 year after, 2.3+-0.4; 3 years, 1.8+-0.3; 5 years, 1.5+-0.3; 7 years, 1.3+-0.3; and 9 years, 1.0+-0.3) and greater curvatures (before, 2.9+-0.4; 1 year after, 1.9+-0.3; 3 years, 1.4+-0.4; 5 years, 1.3+-0.3; 7 years, 1.1+-0.2; and 9 years, 0.6+-0.3). | 25521735 |
| Inflammation, Atrophic | Altered Intercellular Communication | Atrophy scores improved more quickly after eradication than chronic inflammation scores at both the lesser (before, 2.4+-0.5; 1 year after, 1.8+-0.4; 3 years, 0.8+-0.3; 5 years, 0.3+-0.1; 7 years, 0.0; and 9 years, 0.0) and greater curvatures (before, 2.2+-0.4; 1 year after, 1.3+-0.3; 3 years, 0.5+-0.3; 5 years, 0.0; 7 years, 0.0; and 9 years, 0.0). | 25521735 |
| Alzheimers Disease", Periodontitis, Inflammation, Data types - Address | Altered Intercellular Communication | Periodontitis and Alzheimer disease (AD) are associated with systemic inflammation. | 25522313 |
| Chronic Kidney Diseases | Altered Intercellular Communication | Diagnostic validation and prognostic significance of the Malnutrition-Inflammation Score in nondialyzed chronic kidney disease patients. | 25523451 |
| Inflammation, Malnutrition, Chronic Kidney Diseases | Altered Intercellular Communication | Malnutrition and inflammation are highly prevalent and intimately linked conditions in chronic kidney disease (CKD) patients that lead to a state of protein-energy wasting (PEW), the severity of which can be assessed by the Malnutrition-Inflammation Score (MIS). | 25523451 |
| Inflammation, Malnutrition | Altered Intercellular Communication | A structural equation model with two latent variables (assessing simultaneously malnutrition and inflammation factors) demonstrated good fit to the observed data. | 25523451 |
| Psoriatic Juvenile Idiopathic Arthritis, Diamond-Blackfan Anemia 1, Certified Midwife | Altered Intercellular Communication | To investigate whether the serum levels of inflammation-related cytokines might be different between the healthy individuals and the psoriatic patients diagnosed of three varied Chinese medicine (CM) syndromes [blood-stasis syndrome (BSS), blood-dryness syndrome (BDS) and wind-heat syndrome (WHS)]. | 25523599 |
| Inflammation, Extravasation, Chronic Spontaneous Urticaria | Altered Intercellular Communication | As Th2-initiating cytokines play a role in mast cell activation, inflammation and vascular leakage in CSU, these findings may also have therapeutic implications. | 25523947 |
| Inflammation, Rheumatoid Arthritis, Cardiovascular system | Altered Intercellular Communication | Serum amyloid A as a marker of persistent inflammation and an indicator of cardiovascular and renal involvement in patients with rheumatoid arthritis. | 25525305 |
| Inflammation | Altered Intercellular Communication | Recurrent assessment of SAA may facilitate searching patients with persistent inflammation and risk of extra-articular complications. | 25525305 |
| Calcinosis, Aortic valve structure | Altered Intercellular Communication | Early aortic valve inflammation precedes calcification: a longitudinal FDG-PET/CT study. | 25525744 |
| Inflammation, Calcinosis | Altered Intercellular Communication | Recent data shows a relationship between aortic valve (AV) inflammation and calcification. | 25525744 |
| Endocarditis | Altered Intercellular Communication | However, direct evidence linking early valve inflammation (prior to hemodynamic compromise) to subsequent calcium (Ca) deposition is lacking in humans. | 25525744 |
| Inflammation | Altered Intercellular Communication | We sought to test the hypothesis whether local AV inflammation predisposes to subsequent AV Ca deposition. | 25525744 |
| Inflammation | Altered Intercellular Communication | AV inflammation was determined by measuring FDG uptake (maximum standardized uptake value, SUVmax) within the AV on baseline PET/CT. | 25525744 |
| Inflammation, doxorubicin/vincristine protocol, Calcinosis | Altered Intercellular Communication | Moreover, AV inflammation (AV SUVmax) independently predicted subsequent calcification after adjusting for cardiovascular risk factors [OR (95%CI): 4.99 (1.30-19.15), p = 0.02]. | 25525744 |
| Sclerosis, Inflammation | Altered Intercellular Communication | The findings suggest that early AV inflammation may predispose to AV sclerosis. | 25525744 |
| Inflammation, Hydrocephalus | Altered Intercellular Communication | We report the unique case of a 9-month-old infant with progressive internal hydrocephalus of unknown origin and developmental delay due to a history of>200 days of inflammation of the central nervous system. | 25525814 |
| Inflammation, Hydrocephalus, Ureaplasma | Altered Intercellular Communication | In preterm infants, in particular, internal hydrocephalus of unknown origin and sustained CSF inflammation are highly suggestive of Ureaplasma meningitis. | 25525814 |
| Vitritis, Vitreous inflammatory cells | Altered Intercellular Communication | A retrospective chart review was performed of keratoprosthesis recipients at Massachusetts Eye and Ear Infirmary, from January 2000 to August 2013, for demographic data, indication(s) for surgery, timing and presentation of vitreous inflammation, and best-corrected visual acuity at baseline, on presentation, and after resolution of vitritis. | 25526075 |
| Orbital Pseudotumor | Altered Intercellular Communication | Twenty-three (23 eyes) of 346 patients developed idiopathic vitreous inflammation after keratoprosthesis implantation. | 25526075 |
| Unknown (origin) (qualifier value), Inflammation, Infectious Endophthalmitis, Pain Distress Question | Altered Intercellular Communication | However, idiopathic vitritis after keratoprosthesis can also mimic infectious endophthalmitis with pain and external signs of inflammation. | 25526075 |
| Inflammation | Altered Intercellular Communication | Vitritis may be a part of a common pathway of chronic inflammation after keratoprosthesis. | 25526075 |
| Necrotizing granulomatous inflammation | Altered Intercellular Communication | For each patient, other etiologies of nonnecrotizing granulomatous inflammation were excluded. | 25526097 |
| Inflammation, Obesity | Altered Intercellular Communication | Diet-induced obesity can induce low-level inflammation and insulin resistance. | 25526310 |
| Inflammation, Diabetes Mellitus | Altered Intercellular Communication | Interleukin-1b (IL-1b) is one of the key proinflammatory cytokines that contributes to the generation of insulin resistance and diabetes, but the mechanisms that regulate obesity-driven inflammation are ill defined. | 25526310 |
| Hepatitis, Neoplasms, Fibrosis Assessment, Somatic mutation, Liver Cirrhosis | Altered Intercellular Communication | Here we sequence tumour and matching control sample pairs of a large cohort of 103 ICC patients in China, resulting in the identification of an ICC-specific somatic mutational signature that is associated with liver inflammation, fibrosis and cirrhosis. | 25526346 |
| Inflammation, Prostate Cancer Outcomes Study | Altered Intercellular Communication | The sirtuin 1 level, which is associated with inflammation, the immune system and insulin metabolism, was higher in the PCOS patients than in the healthy controls. | 25526506 |
| Malignant tumor of colon, Inflammation | Altered Intercellular Communication | The ethiology of colon cancer is largely dependent on inflammation driven oxidative stress. | 25526641 |
| Acute Lung Injury, Inflammation, Alveolar | Altered Intercellular Communication | Acute lung injury (ALI) is characterized by alveolar injury and uncontrolled inflammation. | 25526715 |
| Adenoma, Chromophobe, Pituitary Adenoma | Altered Intercellular Communication | Further evaluations including hormonal screening revealed a clinically non-functioning pituitary adenoma (chromophobe adenoma). | 25526868 |
| Airway structure, Asthma | Altered Intercellular Communication | Occupational exposures, smoking and airway inflammation in refractory asthma. | 25526871 |
| Inflammation, polychondritis | Altered Intercellular Communication | Relapsing polychondritis is a rare disease characterised by inflammation of cartilaginous and proteoglycan rich structures. | 25527201 |
| Inflammation, Diabetes Mellitus | Altered Intercellular Communication | AGEs have been associated with insulin resistance, oxidative stress, and chronic inflammation in patients with diabetes. | 25527756 |
| Fibrous, Inflammation, Calcified (qualifier) | Altered Intercellular Communication | The essence of the disease, whose etiology and pathogenesis remains unclear, is the fibrous tissue infiltration and diffuse inflammation with focal calcifications. | 25527808 |
| Inflammation, Primary malignant neoplasm | Altered Intercellular Communication | In addition, several pathognomonic features of KS, not related to skin fragility such as aging, inflammation and cancer predisposition have been strongly associated with oxidative stress. | 25528446 |
| vascular inflammations | Altered Intercellular Communication | Vascular inflammation in metabolically abnormal but normal-weight and metabolically healthy obese individuals analyzed with 18F-fluorodeoxyglucose positron emission tomography. | 25529544 |
| vascular inflammations, Dental Plaque | Altered Intercellular Communication | (18)F-fluorodeoxyglucose (FDG) positron emission tomography is a useful imaging technique for detecting vascular inflammation that may reflect plaque vulnerability. | 25529544 |
| vascular inflammations | Altered Intercellular Communication | Therefore, we analyzed which body size phenotypes cause the increased vascular inflammation using FDG positron emission tomography. | 25529544 |
| vascular inflammations, Units Of Measure - Siemens | Altered Intercellular Communication | In conclusion, the present study suggests that unique subsets of body size phenotype, such as MHO or metabolically abnormal but normal weight, may have distinct effects on vascular inflammation. | 25529544 |
| Inflammation, Asthma attack, Exacerbation | Altered Intercellular Communication | These results suggest that IL-8 may be more important in airway and systemic inflammation in COPD exacerbations than in asthma attacks. | 25530067 |
| Inflammation, Prostate carcinoma | Altered Intercellular Communication | A total of 274 patients (58.8%) had prostate cancer, 88 patients (18.9%) inflammation, and 104 patients (22.3%) had benign pathology. | 25530382 |
| Inflammation | Altered Intercellular Communication | The combined case finding strategy identified 3160 patients with sIBM compatible ICD-10 codes, and a largely overlapping cohort of 500 patients having muscle biopsies encoded with inflammation. | 25530508 |
| Extrinsic allergic alveolitis, Inflammation, Fibrosis Assessment | Altered Intercellular Communication | Fibrocytes contribute to inflammation and fibrosis in chronic hypersensitivity pneumonitis through paracrine effects. | 25531246 |
| Extrinsic allergic alveolitis, Pneumonitis | Altered Intercellular Communication | Hypersensitivity pneumonitis (HP) represents a lung inflammation provoked by exposure to a variety of antigens. | 25531246 |
| Inflammation, metabolic disturbance | Altered Intercellular Communication | [Associations between basic indicators of inflammation and metabolic disturbances]. | 25531700 |
| Inflammation, Complications of Diabetes Mellitus, metabolic disturbance | Altered Intercellular Communication | Inflammation is involved in initiation and progression of diabetic complications related to cell damage of tissues, especially endothelial cells, and deepening of metabolic disturbances. | 25531700 |
| Hepatosplenomegaly, Exanthema, Fever, CTCAE, Arthralgia, Arthritis, Juvenile-Onset Still Disease, Myalgia, CTCAE 5 | Altered Intercellular Communication | Adult-onset Still's disease is a rare inflammatory condition of unknown origin characterized by high spiking fever, arthralgia, arthritis, myalgia, salmon-colored evanescent rash, and hepatosplenomegaly. | 25532568 |
| Inflammation, Carcinogenesis | Altered Intercellular Communication | Unique database study linking gingival inflammation and smoking in carcinogenesis. | 25533098 |
| Gingivitis, Carcinogenesis, Primary malignant neoplasm | Altered Intercellular Communication | We investigated statistical association between gingival inflammation and cancer in a group of patients followed up for 26 years with the hypothesis that gingival inflammation affects carcinogenesis. | 25533098 |
| Inflammation, Primary malignant neoplasm | Altered Intercellular Communication | Gingival index, marker of gingival inflammation, was higher in the cancer group than in subjects with no cancer. | 25533098 |
| Inflammation, Primary malignant neoplasm | Altered Intercellular Communication | Hence, our present findings showed that together with smoking, gingival inflammation indeed associated with the incidence of cancer in this cohort. | 25533098 |
| Hepatitis | Altered Intercellular Communication | Liver inflammation correlated with mRNA expression of genes regulating ketolysis in the liver (Spearman correlation 0.379-0.388, P < 0.0006 for ACAT1, ACSS2 and BDH1). | 25533197 |
| Ichthyosis Bullosa of Siemens, Gastrointestinal inflammation | Altered Intercellular Communication | Low-grade intestinal inflammation plays a role in the pathophysiology of IBS. | 25533646 |
| Inflammation, Malignant Neoplasms | Altered Intercellular Communication | Accumulating evidence indicates that systemic inflammation response is associated with the prognosis of various cancers. | 25533822 |
| Inflammation, Atrial Fibrillation by ECG Finding | Altered Intercellular Communication | The predictive role of renal function and systemic inflammation on the onset of de novo atrial fibrillation after cardiac surgery. | 25534011 |
| Inflammation, Atrial Fibrillation by ECG Finding | Altered Intercellular Communication | Both systemic inflammation and oxidative stress play a role in the initiation of postoperative atrial fibrillation after cardiac surgery. | 25534306 |
| Inflammation, Attack behavior | Altered Intercellular Communication | The child had a sustained remission of febrile attacks and inflammation after transplant, and during a 5-year follow-up period, psychomotor and neurologic development were normal, without signs of underlying disease or late transplant-related effects. | 25535259 |
| Anxiety, CTCAE 3.0, Inflammation, error | Altered Intercellular Communication | In comparison, basal pulse primarily depended on general physiological parameters and reduced cholinergic control over anxiety and inflammation, together indicating that consistent exposure to terror threats ignites fear-induced exacerbation of preexisting neuro-immune risks of all-cause mortality. | 25535364 |
| Inflammation, Ulcerative Colitis | Altered Intercellular Communication | Patients with CD are twice as likely as UC patients to experience EIM, and more extensive distribution of inflammation in UC increases the risk of EIM. | 25535653 |
| Inflammation, Fatigue | Altered Intercellular Communication | Sicca symptoms of the mouth and eyes, salivary gland capacity, tear secretion, minor salivary gland inflammation, serum autoantibodies, and fatigue were also investigated. | 25535773 |
| Inflammation, Dyssomnias | Altered Intercellular Communication | Sleep disturbance has been associated with inflammation and cytokine activity, and we previously described genetic associations between cytokine polymorphisms and sleep maintenance and duration among adults with HIV/AIDS. | 25535857 |
| Inflammation, Dyssomnias | Altered Intercellular Communication | This study strengthens the evidence for an association between inflammation and sleep disturbance, particularly self-report of habitual SOI. | 25535857 |
| Inflammation, Sleep Apnea, CTCAE | Altered Intercellular Communication | Gender differences in the association of sleep apnea and inflammation. | 25535861 |
| Inflammation, Sleep Apnea, CTCAE | Altered Intercellular Communication | Over the last 15years, many studies have established an association of sleep apnea with inflammation and metabolic aberrations. | 25535861 |
| Inflammation, ASF1A gene, Erosion of bone | Altered Intercellular Communication | Incidence and severity of CIA and histological parameters (inflammation, cartilage degradation, and bone erosion) were not different in WT and CRAMP-/- mice. | 25535966 |
| Inflammation, trauma to the abdomen, Intra-abdominal | Altered Intercellular Communication | Excessive systemic inflammation after abdominal injury or intra-abdominal sepsis is associated with poor outcomes. | 25536308 |
| Decompensation, Inflammation, Liver Dysfunction | Altered Intercellular Communication | However, significantly lower levels were observed during admission for acute decompensation suggesting an impact of systemic inflammation or liver dysfunction on 25(OH)D levels. | 25536647 |
| Cerebral Amyloid Angiopathy, "Alzheimers Disease", Inflammation | Altered Intercellular Communication | Prodromal Alzheimer's disease presenting as cerebral amyloid angiopathy-related inflammation with spontaneous amyloid-related imaging abnormalities and high cerebrospinal fluid anti-Ab autoantibodies. | 25537009 |
| Inflammation, NRG1 protein, human, "Alzheimers Disease", Data types - Address, Vasculitis, CTCAE | Altered Intercellular Communication | Cerebral amyloid angiopathy-related inflammation (CAA-ri), a rare form of vasculitis associated with amyloid-b (Ab) deposition in vessel walls, has been proposed as a spontaneous human model of the amyloid-related imaging abnormalities (ARIA) occurring after anti-Ab immunotherapy for the treatment of Alzheimer's disease (AD). | 25537009 |
| Inflammation, Fatty degeneration, Acute and chronic inflammation | Altered Intercellular Communication | Initial biopsies demonstrated steatosis 77 %, lobular inflammation 39 %, and chronic portal inflammation 56 %. | 25537957 |
| Inflammation, Acute and chronic inflammation, Fatty degeneration, Steatohepatitis | Altered Intercellular Communication | On post-bariatric biopsy, steatosis resolved in 75 %, lobular inflammation resolved in 75 %, chronic portal inflammation resolved in 49 %, and steatohepatitis resolved in 90 %. | 25537957 |
| Inflammation, Prostate carcinoma | Altered Intercellular Communication | The neutrophil-lymphocyte ratio (NLR), proposed as an indicator of cancer-related inflammation, has known prognostic value in prostate cancer. | 25538172 |
| Communicable Diseases, Inflammation | Altered Intercellular Communication | Evidence of central nervous system inflammation in the absence of direct infection suggests an immune-mediated pathophysiology. | 25538215 |
| Cardiovascular system | Altered Intercellular Communication | Pentraxin-3 (PTX3) is an inflammatory marker thought to be more specific to cardiovascular inflammation than C-reactive protein (CRP). | 25538378 |
| Gastrointestinal inflammation, Cystic Fibrosis | Altered Intercellular Communication | Intestinal inflammation and impact on growth in children with cystic fibrosis. | 25539196 |
| Crohn Disease, Gastrointestinal inflammation | Altered Intercellular Communication | Faecal samples for markers of intestinal inflammation, calprotectin, S100A12, and osteoprotegerin, were collected from children with CF, healthy controls (HCs), and Crohn disease (CD). | 25539196 |
| Inflammatory Bowel Diseases, Gastrointestinal inflammation | Altered Intercellular Communication | The pattern of intestinal inflammation in CF is unique and distinct from inflammatory bowel disease, with elevated faecal calprotectin but normal faecal S100A12 and osteoprotegerin concentrations. | 25539196 |
| Gastrointestinal inflammation | Altered Intercellular Communication | The severity of intestinal inflammation, based on faecal calprotectin, significantly correlates with poor growth. | 25539196 |
| Airway structure, ARCN1 gene | Altered Intercellular Communication | Airway inflammation and tiotropium treatment in stable COPD patients. | 25539549 |
| Inflammation, Metabolic Syndrome X | Altered Intercellular Communication | Associations of neighborhood area level deprivation with the metabolic syndrome and inflammation among middle- and older- age adults. | 25539758 |
| Inflammation, Metabolic Syndrome X | Altered Intercellular Communication | The study examines the association of neighborhood socioeconomic deprivation and metabolic syndrome with inflammation. | 25539758 |
| Inflammation, Lung Diseases, Interstitial | Altered Intercellular Communication | TREM-1 and TLR's likely affect patterns of inflammation in various interstitial lung diseases. | 25540922 |
| Tissue damage, Inflammation | Altered Intercellular Communication | Brain lesions observed in patients with CDR, as well as the higher density of cells immunostained with anti-IL17 at these sites, suggest that this cytokine was increasing local inflammation with subsequent tissue damage due to inflammation. | 25541242 |
| Esophagitis | Altered Intercellular Communication | Furthermore, the higher density of mast cells in the esophagus and large bowel of these subjects suggests that these cells might play a major role in esophageal and intestinal inflammation. | 25541242 |
| Autoimmune Diseases, Communicable Diseases, Inflammation | Altered Intercellular Communication | Apoptosis of the lymphocytes plays an essential role in the regulation of inflammatory/immune responses and its abnormalities may contribute to a chronic infection, persistent inflammation and autoimmunity. | 25541498 |
| Diabetic Nephropathy, Inflammation, Diabetes Mellitus | Altered Intercellular Communication | The role of inflammation in both diabetes and diabetic kidney disease (DKD) is becoming more widely accepted. | 25542095 |
| Inflammation, Malnutrition, Chronic Kidney Diseases | Altered Intercellular Communication | Chronic kidney disease is associated with malnutrition and inflammation. | 25542415 |
| Inflammation, Immunocompromised Host | Altered Intercellular Communication | Impact of inflammation and concomitant glucocorticoid administration on plasma concentration of triazole antifungals in immunocompromised patients. | 25542532 |
| Schizophrenia, Inflammation, Cardiovascular Diseases | Altered Intercellular Communication | Our findings provide further evidence that measurement of total and differential WBC counts may be germane to the clinical care of patients with schizophrenia and related disorders, and support an association between inflammation and cardiovascular disease risk in these patients. | 25542737 |
| Inflammation | Altered Intercellular Communication | We explored the possibility that PSF is related to systemic inflammation by investigating polymorphisms in 2 genes that affect the immune response. | 25542762 |
| Gynecologic, Inflammation, Endometriosis | Altered Intercellular Communication | Endometriosis is a chronic gynaecological disorder that is accompanied by inflammation and oxidative stress. | 25543526 |
| Inflammation, Endometriosis | Altered Intercellular Communication | We also measured markers of inflammation and oxidative stress in women with endometriosis. | 25543526 |
| Intravascular Route of Drug Administration, Inflammation, Pulmonary Infarction, Vasculitis, CTCAE | Altered Intercellular Communication | Within affected lung, associated histopathologic changes included occlusive intravascular or perivascular inflammation (89%), intravascular fibrous response (56%), microthrombus formation (44%), vasculitis (28%), and/or pulmonary microinfarction (28%). | 25543660 |
| Degenerative polyarthritis, Arthralgia, Arthritis | Altered Intercellular Communication | To evaluate the ability of the macrophage markers CD163 and CD14 to predict different osteoarthritis (OA) phenotypes defined by severity of joint inflammation, radiographic features and progression, and joint pain. | 25544994 |
| Degenerative polyarthritis, Inflammation | Altered Intercellular Communication | These data support the central role of inflammation as a determinant of OA severity, progression risk, and clinical symptoms, and they suggest a means of readily identifying a subset of patients with an active inflammatory state and worse prognosis. | 25544994 |
| Inflammation, In Cerebrospinal Fluid | Altered Intercellular Communication | Further exploration of the mechanistic explanation is needed, but we suggest this may be from a combination of obstruction of cerebrospinal fluid pathways by blood products and inflammation in the choroid plexus resulting in increased cerebrospinal fluid production. | 25545809 |
| Colorectal Carcinoma, Gastrointestinal inflammation | Altered Intercellular Communication | Toll-like receptor (TLR) 9 plays a role in intestinal inflammation that, in turn, is related to the tumorigenesis of colorectal cancer. | 25546690 |
| Communicable Diseases, Inflammation, Lower Urinary Tract Symptoms, Pain Distress Question | Altered Intercellular Communication | Patients with LUTS (Lower Urinary Tract Symtoms--inflammation, infection, pain) were excluded. | 25546927 |
| Inflammation, Gastroenteritis | Altered Intercellular Communication | Eosinophilic gastroenteritis is a rare condition where eosinophilic inflammation occurs in the gastrointestinal tract in the absence of secondary causes. | 25547198 |
| Communicable Diseases, Inflammation | Altered Intercellular Communication | Neutrophils are rapidly recruited in response to local tissue infection or inflammation. | 25548073 |
| Non-Small Cell Lung Carcinoma | Altered Intercellular Communication | Inflammation-based scoring is a useful prognostic predictor of pulmonary resection for elderly patients with clinical stage I non-small-cell lung cancer. | 25548132 |
| Inflammation, Anemia, Sickle Cell, SLC22A5 gene | Altered Intercellular Communication | Previous studies on the role of inflammation in the pathophysiology of sickle cell disease (SCD) suggested that the CCR5D32 allele, which is responsible for the production of truncated C-C chemokine receptor type 5 (CCR5), could confer a selective advantage on patients with SCD because it leads to a less efficient Th1 response. | 25548430 |
| Septic Shock | Altered Intercellular Communication | Inflammation markers were decreased after the treatment of septic shock in both groups (p<0.05). | 25549485 |
| Inflammation, Atrial Fibrillation | Altered Intercellular Communication | A role for inflammation in the atrial remodeling as well as development and recurrence of AF is known. | 25549592 |
| Inflammation, Carcinogenesis, Colorectal Carcinoma | Altered Intercellular Communication | Inflammation is a process central to carcinogenesis and in particular to colorectal cancer (CRC). | 25549833 |
| Autoimmune Diseases, Inflammation, polychondritis | Altered Intercellular Communication | Relapsing polychondritis is a rare autoimmune disease causing inflammation in cartilaginous structures and other tissues throughout the body. | 25550527 |
| Inflammation, Neoplasms, Malignant Neoplasms | Altered Intercellular Communication | Inflammation and tumor immunology are important in the prognosis of various cancers. | 25550569 |
| Inflammation, Fibrosis Assessment, Stenosis | Altered Intercellular Communication | Strictures develop as a consequence of tissue remodelling and fibrosis due to chronic inflammation. | 25550777 |
| Autoimmune Diseases, Inflammation, Primary malignant neoplasm | Altered Intercellular Communication | The interleukin-1 receptor associated kinases 1 (IRAK1) is a down stream effector molecule of the toll like receptor (TLR) signaling pathway, which is involved in inflammation, autoimmunity and cancer. | 25550857 |
| Granuloma, Granulomatous inflammation, Sarcoidosis, Squamous cell carcinoma, Silicosis, Adenocarcinoma of lung (disorder), Pneumonia, Viral, Hyperplasia | Altered Intercellular Communication | The first patient had squamous cell carcinoma in the left upper lobe of the lung with surrounding necrotizing granulomas and concurrent with silicosis and granulomatous inflammation in the lymph nodes; the second presented with symptoms of viral pneumonia, which was pathologically diagnosed as a lung adenocarcinoma, stage IA, concurrent with sarcoidosis involving the lymph nodes; the last case was diagnosed as squamous cell carcinoma in the right upper lobe of the lung, but lymph nodes showed reactive hyperplasia. | 25550877 |
| Inflammation | Altered Intercellular Communication | Chronic and acute inflammation can be found, and diseases that impair the immune system and pregnancy have been associated with this condition. | 25551590 |
| Malignant Neoplasms | Altered Intercellular Communication | Non-steroidal anti-inflammatory drugs use is associated with reduced risk of inflammation-associated cancers: NIH-AARP study. | 25551641 |
| Inflammation, Malignant Neoplasms | Altered Intercellular Communication | Chronic inflammation has been linked to cancers, and use of non-steroidal anti-inflammatory drugs (NSAIDs) has been associated with reduced risk of several cancers. | 25551641 |
| vascular inflammations, Platelet aggregation measurement | Altered Intercellular Communication | Mean platelet volume (MPV) is a determinant of platelet functionality and increased MPV is associated with an increased risk of vascular inflammation. | 25552162 |
| Inflammation, Cholesteatoma | Altered Intercellular Communication | Additional control of inflammation was performed in 2 patients at second-stage surgery for cavity problem and cholesteatoma, respectively. | 25552887 |
| Inflammation, Sleep Apnea, Obstructive | Altered Intercellular Communication | Inflammation is thought to be involved in the pathogenesis of obstructive sleep apnea syndrome (OSAS). | 25553801 |
| Inflammation | Altered Intercellular Communication | Declines in inflammation predict greater white matter microstructure in older adults. | 25554492 |
| Neurodegenerative Disorders, Inflammation | Altered Intercellular Communication | Protracted systemic inflammation has been associated with adverse effects on cognition and brain structure and may accelerate neurodegenerative disease processes; however, it is less clear whether changes in inflammation are associated with brain structure. | 25554492 |
| Inflammation | Altered Intercellular Communication | These include genes involved in neurogenesis (NPDC1) and inflammation (HERC5), as well as alcoholism-associated genes ADCY9, CKM, and PHOX2A. | 25555412 |
| Inflammation | Altered Intercellular Communication | The pathophysiology is poorly understood, but low-grade systemic inflammation has been suggested as an important component. | 25555530 |
| Inflammation, Chronic Fatigue Syndrome | Altered Intercellular Communication | Adolescent CFS patients are burdened by symptoms that might suggest low-grade systemic inflammation, but plasma levels of individual cytokines as well as cytokine network measures were not different from healthy controls, and there were no associations between symptoms and cytokine expression in the CFS group. | 25555530 |
| Communicable Diseases, Inflammation, Tonsillitis | Altered Intercellular Communication | Chronic tonsillitis is the persistent inflammation of the tonsillar tissue that occurs due to recurrent, acute or subclinical infection. | 25555639 |
| Tonsillitis, Hypertrophy | Altered Intercellular Communication | The recurrent and chronic inflammation of palatine tonsils sometimes results in hypertrophy. | 25555639 |
| Inflammation, Thrombosis | Altered Intercellular Communication | Activated platelets play a key role in inflammation and atherothrombosis, with mean platelet volume (MPV) is an early marker of platelet activation. | 25556499 |
| Inflammation, Ischemic stroke | Altered Intercellular Communication | Recombinant T-cell receptor ligand RTL1000 limits inflammation and decreases infarct size after experimental ischemic stroke in middle-aged mice. | 25556831 |
| Ischemic stroke | Altered Intercellular Communication | These findings suggest that RTL1000 protects against ischemic stroke in middle-aged male mice by limiting post-ischemic inflammation. | 25556831 |
| Hyperammonemia, Inflammation, Impaired cognition | Altered Intercellular Communication | Our observations lead to the hypothesis that oxidative stress and increased peroxynitrite formation would mediate the synergistic effects of hyperammonemia and inflammation on cognitive and motor impairment in MHE. | 25557123 |
| Inflammation, muscle mass | Altered Intercellular Communication | Ageing is also associated with low grade inflammation (LGI), which has been negatively correlated with muscle mass and strength. | 25557160 |
| Inflammation, Primary malignant neoplasm | Altered Intercellular Communication | TGF-b-activated protein kinase 1 (TAK1) is a critical mediator in inflammation, immune response and cancer development. | 25557171 |
| Inflammation, Neoplasm Metastasis, Neoplasms | Altered Intercellular Communication | There is mounting evidence that immune cells may trigger various mechanisms that enhance tumor growth and metastasis, but no data on the peritumoral inflammation is available for PeCa. | 25557886 |
| Inflammation, Ischemic stroke | Altered Intercellular Communication | Inflammation plays an important role in acute ischemic stroke. | 25558553 |
| Inflammation, Ischemic stroke | Altered Intercellular Communication | Relationships between higher levels of inflammation markers, especially serum amyloid A, and the severity of acute ischemic stroke were shown. | 25558553 |
| Inflammation, Pulmonary Embolism | Altered Intercellular Communication | Preliminary evidence suggests that inflammation plays a role in the development and prognosis of pulmonary embolism (PE). | 25558558 |
| Chronic inflammation, Disease | Altered Intercellular Communication | Profiling phospholipid (PL) FAs and their respective oxylipids could predict which obese individuals are more likely to suffer from diseases associated with chronic inflammation or oxidative stress. | 25559239 |
| Hepatitis A, Inflammation, Fibrosis Assessment, Fatty degeneration | Altered Intercellular Communication | We observed heavy ethanol consumption, 12.0%; viral hepatitis, 26.5%; steatosis without heavy ethanol consumption, 43.4%; inflammation, 45.6%; fibrosis, 26.2% and bridging fibrosis/cirrhosis, 29.4%. | 25559280 |
| Inflammation, Prostate carcinoma | Altered Intercellular Communication | A close relationship between aging, inflammation, and prostate cancer is widely accepted. | 25560177 |
| Inflammation, Carcinogenesis | Altered Intercellular Communication | NF-kB increases inflammation, carcinogenesis and metastatic potential in the prostate. | 25560177 |
| Deficit, Impaired cognition | Altered Intercellular Communication | We suggest that the cognitive impairment due to hormonal deficit in the postmenopausal period could be emphasized by the early structural decline of gray matter in female DS subjects. | 25560246 |
| Inflammation | Altered Intercellular Communication | This may be a consequence of inflammation on the fibrous trigones and surrounding annulus. | 25560735 |
| Inflammation, Primary malignant neoplasm, Ulcerative Colitis | Altered Intercellular Communication | Clinical factors were independently associated with low 5-MeC levels after adjusting for age and sex, including cancer stages II-IV, presence of UC in situ, and marked inflammation. | 25561224 |
| Inflammation, Hepatitis, Liver Cirrhosis | Altered Intercellular Communication | Bone Mineral Density, Bone Turnover, and Systemic Inflammation in Non-cirrhotics with Chronic Hepatitis C. Whether chronic HCV, a disease characterized by systemic inflammation, impacts bone mineral density (BMD) independent of cirrhosis is unknown. | 25563723 |
| Inflammation, Liver Cirrhosis | Altered Intercellular Communication | We aimed to evaluate the association between BMD, systemic inflammation, and markers of bone turnover in chronic HCV without cirrhosis. | 25563723 |
| Inflammation, Rupture | Altered Intercellular Communication | This leads to adventitial inflammation via IL-6 and results in aortic expansion and rupture. | 25563839 |
| Disease Progression, Pancreatic Intraductal Papillary Mucinous Neoplasm | Altered Intercellular Communication | To evaluate the association of tumor-associated neutrophils (TANs) with malignant progression in intraductal papillary mucinous neoplasms (IPMNs) and to study the cyst fluid from these lesions for biomarkers of the inflammation-carcinogenesis association. | 25563865 |
| Inflammation | Altered Intercellular Communication | A multiplexed assay was performed to evaluate 87 different cyst fluid proteins, including cyst fluid inflammatory markers (CFIMs), as possible surrogate markers for parenchymal inflammation. | 25563865 |
| Inflammation, Anger | Altered Intercellular Communication | Expression of anger and ill health in two cultures: an examination of inflammation and cardiovascular risk. | 25564521 |
| Inflammation, Leishmaniasis, Visceral, Rheumatoid Factor, Collagen Diseases | Altered Intercellular Communication | African patients with Leishmania donovani infections have signs of strong systemic inflammation and high levels of circulating immune complexes (IC) and rheumatoid factor (RF), all serologic markers of rheumatic disease. | 25565324 |
| Inflammation, Genus: Leishmania | Altered Intercellular Communication | As inflammation in general is associated with citrullination, we sought to investigate ACPA responses in Sudanese Leishmania patients. | 25565324 |
| Inflammation, Fibrosis Assessment, Schistosoma mansoni, Intestine Resection | Altered Intercellular Communication | Histological examination of the resected bowel revealed Schistosoma mansoni eggs within the mucosa, submucosa of the ileum, caecum and ascending colon, granulomatous inflammation with foreign body giant cells accompanied by fibrosis and eosinophilic infiltrate into the mucosa. | 25566612 |
| Infection caused by Helicobacter pylori | Altered Intercellular Communication | We suggested that IDA/ID associated with H. pylori infection might be mediated by inflammation-driven hepcidin production. | 25567795 |
| Inflammation, Acute infectious disease | Altered Intercellular Communication | There is a positive correlation between the parameters of inflammation and glucoregulation in diabetics with acute infection. | 25568525 |
| Malaria, Vivax, physiopathological | Altered Intercellular Communication | Parasite biomass-related inflammation, endothelial activation, microvascular dysfunction and disease severity in vivax malaria. | 25569250 |
| Inflammation, Malaria, Vivax | Altered Intercellular Communication | Peripheral vivax parasitemia correlated with endothelial activation (angiopoietin-2, von-Willebrand-Factor [VWF], E-selectin), whereas markers of total vivax biomass correlated only with systemic inflammation (IL-6, IL-10). | 25569250 |
| Inflammation, Malaria, Vivax, physiopathological | Altered Intercellular Communication | Endothelial activation, associated with circulating parasites, and systemic inflammation may contribute to pathology in vivax malaria, with microvascular dysfunction likely contributing to impaired tissue perfusion. | 25569250 |
| Inflammation, Calcinosis, Atherosclerosis | Altered Intercellular Communication | Histological findings in patients with CAS extremely resemble those of atherosclerosis and include accumulation and modification of lipoproteins, inflammation, extracellular matrix remodeling, and calcification. | 25569379 |
| Inflammation, Cicatricial ectropion | Altered Intercellular Communication | The delicate local anatomy of the lower eyelid region makes this region particularly susceptible for complications after silicone augmentation including local inflammation, tissue retraction, and consecutive cicatricial ectropion leading to lagophthalmus and ocular surface irritation. | 25569426 |
| Inflammation | Altered Intercellular Communication | The CH success rate of carious primary molar DPC justifies further research based on careful initial diagnosis ofpulp inflammation reversibility. | 25571680 |
| Degenerative polyarthritis, Inflammation | Altered Intercellular Communication | Agonists of PPARg inhibit inflammation and reduce generation of cartilage degradation products both in vitro and in vivo, and reduce the development/progression of cartilage lesions in OA animal models. | 25572230 |
| Inflammation, Hyperplasia | Altered Intercellular Communication | Periostin plays an important role during epidermal hyperplasia in IMQ-induced skin inflammation, independently of the IL-23-IL-17/IL-22 axis. | 25572557 |
| Inflammation, Primary malignant neoplasm | Altered Intercellular Communication | High mobility group box 1 (HMGB1) has been proved to be implicated in a variety of cell physiological and pathological behaviors including immune response, inflammation and cancer. | 25572734 |
| Inflammation, Atherosclerosis | Altered Intercellular Communication | Cigarette smoking and cardiovascular events: role of inflammation and subclinical atherosclerosis from the MultiEthnic Study of Atherosclerosis. | 25573855 |
| Inflammatory Bowel Diseases | Altered Intercellular Communication | These findings propose FSPs as potential novel class of inflammation-associated antigens and this in turn may have implications for screening, diagnosis as well as clinical management of patients suffering from IBD and other inflammatory conditions. | 25574094 |
| Inflammatory Bowel Diseases | Altered Intercellular Communication | These findings propose FSPs as potential novel class of inflammation-associated antigens and this in turn may have implications for screening, diagnosis as well as clinical management of patients suffering from IBD and other inflammatory conditions. | 25574094 |
| Inflammation, Infection, Tissue injury | Altered Intercellular Communication | Inflammation is a normal host defense reaction to infections and tissue injury. | 25574748 |
| Inflammation | Altered Intercellular Communication | The results showed that depending on the period of the disease, the process of inflammation is deregulated in different ways. | 25574748 |
| Inflammation, HIV Antibodies | Altered Intercellular Communication | To determine associations between circulating markers of immune activation, immune cell senescence, and inflammation with HIV-associated abnormalities of pulmonary function. | 25574956 |
| Inflammation, HIV Antibodies, Lung diseases, HIV Infections | Altered Intercellular Communication | Immune activation, immune senescence, and chronic inflammation are characteristics of chronic HIV infection that have been associated with other HIV-associated comorbidities and may be related to pulmonary disease in this population. | 25574956 |
| Colorectal Carcinoma, Neoplasms | Altered Intercellular Communication | Colorectal Cancer, Systemic Inflammation, and Outcome: Staging the Tumor and Staging the Host. | 25575264 |
| Inflammation | Altered Intercellular Communication | By modulating the gene expression of immune cells, immunonutrition could make it easier for the organism to adapt to the systemic inflammation and oxidative stress induced by RCT. | 25575640 |
| Inflammation, Mediastinal Emphysema | Altered Intercellular Communication | Subsequent abdominal imaging showed inflammation in the right iliac fossa, retroperitoneal air pockets with inflammation, and signs of pneumomediastinum. | 25576508 |
| Inflammation, Malignant Neoplasms | Altered Intercellular Communication | Histopathological examination of the resected specimen revealed intense inflammation of the caecum and no signs of malignancy. | 25576508 |
| Inflammation, Periodontitis, Alveolar Bone Loss | Altered Intercellular Communication | IL-6 plays critical roles in bone resorption and the pathogenesis of periodontitis in both inflammation and alveolar bone loss. | 25576892 |
| atherosclerotic | Altered Intercellular Communication | Pre-clinical data suggest the existence of a cardiosplenic axis, wherein activation of hematopoietic tissues (notably in the spleen) results in liberation of proinflammatory leukocytes and accelerated atherosclerotic inflammation. | 25577441 |
| Inflammation, Arteritis | Altered Intercellular Communication | Splenic activity increased after ACS and was significantly associated with multiple indices of inflammation: 1) up-regulated gene expression of proinflammatory leukocytes; 2) increased C-reactive protein; and 3) increased arterial wall inflammation (FDG uptake). | 25577441 |
| Granuloma, Interstitial inflammation | Altered Intercellular Communication | Bronchoscopy showed ill-defined granulomas and chronic interstitial inflammation. | 25577532 |
| Inflammation, Obesity, Abdominal, Liver damage, Antihypertensive Agents | Altered Intercellular Communication | After feature selection was performed, several metabolites and cardiometabolic risk markers, including abdominal obesity and markers of liver damage, inflammation, and oxidative stress were significantly perturbed in Quintile 5 (hypertensives) compared with Quintile 1 (P < .05). | 25577962 |
| Inflammation, Polyposis, Gastric | Altered Intercellular Communication | The majority of gastric polyps are asymptomatic, occurring secondary to inflammation. | 25578789 |
| Inflammation, Dermatitis, Atopic | Altered Intercellular Communication | Interestingly, omalizumab appeared to induce lymphocyte polarisation toward a type 2 immune response and to be able to quench eosinophil-mediated inflammation, particularly in atopic dermatitis patients. | 25578818 |
| Inflammation, Asthma, Impaired lung function | Altered Intercellular Communication | Children and adults with asthma and impaired lung function have been reported to have low-grade systemic inflammation, but it is unknown whether this inflammation starts before symptoms and in particular whether low-grade inflammation is present in asymptomatic neonates with reduced lung function. | 25579483 |
| Airway structure | Altered Intercellular Communication | Roxithromycin can reduce airway inflammation and airway thickness of dilated bronchus in patients with NCFB. | 25580060 |
| Inflammation, Osage language, Hypoxia, Diabetes Mellitus, Obesity, Hypogonadism | Altered Intercellular Communication | Some are shared with obesity, including hypogonadism, altered adrenergic tone, inflammation, oxidative stress, vitamin D deficiency and diabetes mellitus; others are specific to OSA, such as hypoxia and altered glucocorticoids regulation. | 25580607 |
| Pigmented lesions, Abnormal color, Malignant Neoplasms | Altered Intercellular Communication | The main diagnostic categories included benign exophytic lesions (45.3%), white benign lesions (13.5%), potentially malignant lesions/disorders (10.1%), intrabony lesions (9.8%), mucosal discoloration (7.8%), benign pigmented lesions (7.3%), chronic trauma/inflammation (3.9%), and oral malignancy (2.1%). | 25580799 |
| Thyroid stimulating hormone measurement | Altered Intercellular Communication | Diagnosis of amiodarone-induced thyroid dysfunction was based on hormonal dosages of TSH, FT4 and FT3, endocrinological examination and thyroid ultrasound. | 25581954 |
| Inflammation, Primary malignant neoplasm, hypopharynx | Altered Intercellular Communication | Enhanced contact endoscopy allows for predicting histologic changes of laryngeal and hypopharyngeal lesions from inflammation to cancer on based on fine evaluation of the neoangiogenetic changes of the chorion. | 25582112 |
| Inflammation, FBN2 wt Allele, Bacterial Infections | Altered Intercellular Communication | Inflammation induced by bacterial infections might play a role in the pathogenesis of CCA. | 25582431 |
| Polymyositis, Dermatomyositis, Rhabdomyositis | Altered Intercellular Communication | Clinical values of FDG PET in polymyositis and dermatomyositis syndromes: imaging of skeletal muscle inflammation. | 25582454 |
| Inflammation, Total Clearance Predicted Normalized by Dose, Lymphoproliferative Disorders, Pseudoepitheliomatous hyperplasia | Altered Intercellular Communication | The pathogenetic mechanism of CD30(+) cutaneous lymphoproliferative disorders (CLPD) associated with pseudocarcinomatous hyperplasia (PCH) and granulocytic inflammation surrounding atypical CD30(+) lymphocytes remains unclear. | 25582534 |
| Inflammation | Altered Intercellular Communication | Ninety-eight subjects aged 10-24 yr with newly-diagnosed T2DM had general inflammation, anthropometric, laboratory and CIMT data collected, and were divided into three groups based on TG/HDL-C tertiles. | 25582650 |
| Inflammation, Primary malignant neoplasm | Altered Intercellular Communication | Interleukin-32 (IL-32) is a novel cytokine involved in inflammation and cancer development. | 25583360 |
| Inflammation, Neoplasm Metastasis, Obesity, Diabetes Mellitus | Altered Intercellular Communication | Unraveling the functional role of OPN isoforms in systemic inflammation is essential to understanding their significance as therapeutic targets in diabetes and obesity, and during metastasis development in PDA. | 25583441 |
| Airway structure | Altered Intercellular Communication | Asthma is characterized by chronic airway inflammation that is associated with structural changes termed airway remodeling. | 25584916 |
| Inflammation | Altered Intercellular Communication | Recently, cytokines/mediators that augment inflammation have been attracting attention in this field. | 25584916 |
| Inflammation | Altered Intercellular Communication | This process may lead to inflammation, destabilization of blood vessels, and trigger remodeling. | 25584916 |
| Cessation of life, Inflammation, Atrial Fibrillation, Choline Dehydrogenase, Mitochondrial | Altered Intercellular Communication | Modeled as a continuous variable, after adjustment for anthropomorphic measures, traditional risk factors, markers of inflammation, and other adipokines, significant associations were noted for HF (HR 1.4, CI 1.0-2.0), hard and all CVD (HR 1.3, 1.1-1.7 and 1.3, 1.1-1.6, respectively), and CHD (HR 1.31, 1.0-1.6), but not for AF or death. | 25585029 |
| Inflammation | Altered Intercellular Communication | Systemic inflammation and oxidative stress in hemodialysis patients are associated with down-regulation of Nrf2. | 25585822 |
| Inflammation, Cardiac complication, Chronic Kidney Diseases | Altered Intercellular Communication | Oxidative stress and inflammation are common features and the main mediators of progression of chronic kidney disease (CKD) and its cardiovascular complications. | 25585822 |
| Inflammation | Altered Intercellular Communication | Acute inflammation is necessary to initiate proper wound healing, while chronic inflammation abrogates wound healing. | 25586463 |
| Inflammation | Altered Intercellular Communication | Sustained signalling of TLR9 and TLR7 contributes to chronic inflammation by activating the plasmacytoid dendritic cells. | 25586463 |
| Inflammation, Sleep Apnea, Obstructive, Metabolic Syndrome X | Altered Intercellular Communication | Sleepiness, inflammation and oxidative stress markers in middle-aged males with obstructive sleep apnea without metabolic syndrome: a cross-sectional study. | 25586501 |
| Inflammation, Osage language | Altered Intercellular Communication | Both conditions, if present in OSA, have been reported to be associated with inflammation and disruption of oxidative stress balance that impair the cardiovascular system. | 25586501 |
| Inflammation, Primary malignant neoplasm, Neoplasms | Altered Intercellular Communication | Inflammation plays an important role in tumor proliferation and survival in cancer patients. | 25586599 |
| Inflammation | Altered Intercellular Communication | An accelerated tryptophan breakdown rate is associated with inflammation and immune activation. | 25586781 |
| Parkinson Disease, Inflammation, palladium | Altered Intercellular Communication | Inflammatory mediators may reflect a role of systemic inflammation in the neurodegenerative process of Parkinson's disease (PD). | 25587378 |
| Diabetic Nephropathy, Inflammation | Altered Intercellular Communication | Recent evidence suggests that chronic subclinical inflammation plays a key role in the pathogenesis and progression of diabetic nephropathy. | 25587544 |
| Microalbuminuria, Inflammation, Demographics Domain, Diabetes Mellitus, Non-Insulin-Dependent | Altered Intercellular Communication | Aim of the present study was to investigate possible correlation between the presence and degree of microalbuminuria and markers of inflammation in patients with type 2 diabetes mellitus (DM). | 25587544 |
| Inflammation | Altered Intercellular Communication | Despite the use of HAART to control HIV, systemic immune activation and inflammation persists with the consequence of developing serious non-AIDS events. | 25587909 |
| Inflammation, Gastrointestinal dysfunction | Altered Intercellular Communication | Gene expression was correlated with systemic markers of intestinal barrier dysfunction and inflammation and intestinal microbiota composition. | 25587909 |
| Arteritis, Dental Plaque, Cerebrovascular accident | Altered Intercellular Communication | Carotid artery plaque inflammation is thought to be an important marker of plaque vulnerability and increased stroke risk. | 25588553 |
| Inflammation, Dental Plaque | Altered Intercellular Communication | The level of agreement between (18)F-FDG uptake (mean SUVmax and SUVmax ), and target-to-background ratio, symptoms, plaque echolucency, and histological evidence of inflammation was assessed. | 25588553 |
| Inflammation | Altered Intercellular Communication | The amount of (18)F-FDG uptake in plaques and the amount of inflammation on histological assessment were significantly correlated (r = 0*521, P = 0*003). | 25588553 |
| Inflammation | Altered Intercellular Communication | (18)F-FDG uptake on PET/CT correlated with histological assessments of inflammation and was higher in patients with symptomatic compared with asymptomatic carotid artery plaques. | 25588553 |
| Inflammation, Carotid Atherosclerosis | Altered Intercellular Communication | These results support the use of (18)F-FDG PET/CT in the detection inflammation in carotid atherosclerosis, which may be of help in the detection of vulnerable plaques. | 25588553 |
| Inflammation, N-Acetylneuraminic acid storage disease | Altered Intercellular Communication | NSD and granulometry index showed the highest accuracy in identifying a significant plaque inflammation, especially if used together in a two-step algorithm. | 25588802 |
| Inflammation, Ulcerative Colitis | Altered Intercellular Communication | Conventional oral corticosteroids are effective at reducing inflammation associated with ulcerative colitis (UC); however, systemic adverse effects limit their use. | 25588902 |
| Inflammation, Optic Neuritis | Altered Intercellular Communication | Optic neuritis (ON) is an acute episode of inflammation in the visual pathway (VP). | 25588974 |
| Inflammation, Chronic Kidney Diseases | Altered Intercellular Communication | Furthermore, protein fragments associated with progression of CKD originated mostly from proteins related to inflammation and tissue repair. | 25589610 |
| Inflammation, Impaired cognition, Nerve Degeneration | Altered Intercellular Communication | Whether chronic inflammation plays a causal role in cognitive decline in aging and neurodegeneration has not been established. | 25589773 |
| Inflammation, Cognition Disorders | Altered Intercellular Communication | Here we report a mechanistic link between chronic inflammation and aging microglia and a causal role of aging microglia in neurodegenerative cognitive deficits. | 25589773 |
| Abscess, Inflammation | Altered Intercellular Communication | One week and 6 weeks after surgery, the presence of suture abscesses and focal inflammation was assessed at the entrance and exit of the sutures. | 25590472 |
| Intraocular inflammation | Altered Intercellular Communication | Postmarketing analysis of aflibercept-related sterile intraocular inflammation. | 25590968 |
| Low Vision, Intraocular inflammation, Hypopyon, Pain Distress Question | Altered Intercellular Communication | Most cases consisted of initial loss of vision and intraocular inflammation without prominent redness, severe pain, or hypopyon. | 25590968 |
| Inflammation, Unspecified visual loss | Altered Intercellular Communication | Although final vision was overall unchanged, some patients developed permanent vision loss, which may have resulted from inflammation and/or progression of the underlying disease. | 25590968 |
| Inflammation, Infectious Endophthalmitis | Altered Intercellular Communication | Distinguishing sterile inflammation and infectious endophthalmitis at the time of presentation may often be difficult, and cautious evaluation and management of these patients are warranted. | 25590968 |
| Inflammation, Papilledema | Altered Intercellular Communication | Besides a unilateral papillary edema, serological investigations revealed elevated inflammation parameters with a positive (cytoplasmic) anti-neutrophil cytoplasmic autoantibodies (c-ANCA) titer. | 25591900 |
| Inflammatory Bowel Diseases, Inflammation, Damage | Altered Intercellular Communication | Plain magnetic resonance imaging as an alternative in evaluating inflammation and bowel damage in inflammatory bowel disease--a prospective comparison with conventional magnetic resonance follow-through. | 25592192 |
| Inflammation, Non-Small Cell Lung Carcinoma, Neoplasm Metastasis, Neoplasms | Altered Intercellular Communication | Recent evidence demonstrated an enhanced metastasis of non-small cell lung cancer (NSCLC) cells induced by lipopolysaccharide (LPS) stimulation, which reflected an important role of inflammation in tumor progression. | 25592377 |
| Hyperglycemia, Inflammation | Altered Intercellular Communication | Increased plasma DPP4 activities predict new-onset hyperglycemia in Chinese over a four-year period: possible associations with inflammation. | 25592717 |
| Inflammation, Hyperglycemia | Altered Intercellular Communication | Our objective was to determine whether DPP4 acts as a link between low-grade chronic inflammation and hyperglycemia. | 25592717 |
| Inflammation, Chronic Kidney Diseases, Diabetes Mellitus | Altered Intercellular Communication | Inflammation plays an important role in the pathogenesis of chronic kidney disease (CKD) and diabetes mellitus. | 25592836 |
| Inflammation, Pterygium Of Conjunctiva And Cornea | Altered Intercellular Communication | Chronic inflammation is a critical process in pterygium development and progression, including promotion of angiogenesis. | 25593504 |
| Communicable Diseases, Inflammation | Altered Intercellular Communication | C-reactive protein (CRP) and the erythrocyte sedimentation rate (ESR) are often ordered together in patients with suspected infection or inflammation. | 25594234 |
| ARCN1 gene, Inflammation | Altered Intercellular Communication | Collectively, these findings suggest that IL-33 expression levels are increased in COPD and related to airway and systemic inflammation. | 25595648 |
| Inflammation, Hypertension, CTCAE, Liver Cirrhosis | Altered Intercellular Communication | Liver cirrhosis is associated with inflammation which is aggravated by portal hypertension. | 25595667 |
| Inflammation | Altered Intercellular Communication | Inflammation is believed to play a pivotal role in the etiology of postoperative AF. | 25596472 |
| Inflammation, Subarachnoid Hemorrhage, Aneurysmal | Altered Intercellular Communication | Inflammation, negative nitrogen balance, and outcome after aneurysmal subarachnoid hemorrhage. | 25596503 |
| ACSM3 gene, Inflammation, Subarachnoid Hemorrhage | Altered Intercellular Communication | To analyze the impact of inflammation and negative nitrogen balance (NBAL) on nutritional status and outcomes after subarachnoid hemorrhage (SAH). | 25596503 |
| ACSM3 gene, Inflammation | Altered Intercellular Communication | Negative NBAL after SAH is influenced by inflammation and associated with an increased risk of HAI and poor outcome. | 25596503 |
| ACSM3 gene, Inflammation | Altered Intercellular Communication | Underfeeding and systemic inflammation are potential modifiable risk factors for negative NBAL and poor outcome after SAH. | 25596503 |
| Deglutition Disorders, Radiation injury, Inflammatory disease of mucous membrane | Altered Intercellular Communication | The most frequent grade 3-4 adverse events were mucosal inflammation (25 [40%] of 62 patients in the chemoradiotherapy group vs 37 [42%] of 89 patients in the radiotherapy plus panitumumab group), dysphagia (20 [32%] vs 36 [40%]), and radiation skin injury (seven [11%] vs 21 [24%]). | 25596659 |
| Deglutition Disorders, Radiation injury, Inflammatory disease of mucous membrane | Altered Intercellular Communication | The most frequent grade 3-4 adverse events were dysphagia (17 [27%] of 63 patients in the chemoradiotherapy group vs 35 [40%] of 87 in the panitumumab plus chemoradiotherapy group), mucosal inflammation (15 [24%] vs 48 [55%]), and radiation skin injury (eight [13%] vs 27 [31%]). | 25596660 |
| Frontotemporal dementia | Altered Intercellular Communication | This study suggests that glutamate excitotoxicity may play a role in the pathogenesis of bvFTD and that [(11)C]ABP688 may prove a suitable marker of glutamatergic neurotransmission in vivo. | 25596865 |
| Inflammation, hepcidin, Anemia | Altered Intercellular Communication | Mass spectrometry evaluation of the hepcidin-25 assay in the differential diagnosis of iron deficiency anaemia with concurrent inflammation and anaemia of inflammation in elderly patients. | 25598191 |
| Inflammation, hepcidin, Intradermal Route of Drug Administration | Altered Intercellular Communication | Receiver operating characteristics curve analysis revealed that mass spectrometry analysis of hepcidin-25 does not appear to be superior to ferritin in the diagnosis of ID in elderly anaemic patients with concurrent inflammation. | 25598191 |
| Inflammation, Metabolic Diseases | Altered Intercellular Communication | Elevated g-glutamyltransferase (GGT) is an important risk factor for cardiometabolic diseases, which may result from chronic low-grade inflammation. | 25598349 |
| Inflammation, Metabolic Diseases | Altered Intercellular Communication | Leukocyte count is widely considered a marker of inflammation and is also an independent predictor of cardiometabolic diseases. | 25598349 |
| Inflammation | Altered Intercellular Communication | These findings indicate that serum GGT may be closely related with subclinical low-grade inflammation in children and adolescents. | 25598349 |
| ARCN1 gene, Inflammation, Neoplasms | Altered Intercellular Communication | Inflammation might have a key pathogenetic role linking the above tumor markers with the severity of COPD. | 25598350 |
| Inflammation, Epilepsy, Trauma, Nervous System | Altered Intercellular Communication | It has been demonstrated that inflammation may contribute to epileptogenesis and cause neuronal injury in epilepsy. | 25598431 |
| Inflammation, Hepatic Insufficiency, physiopathological, Hypertension, CTCAE, Liver Cirrhosis | Altered Intercellular Communication | In patients with cirrhosis, serum ferritin levels are associated with markers of liver insufficiency, inflammation, and circulatory dysfunction but not portal hypertension. | 25599219 |
| Inflammation, Extracellular Matrix, Autoinflammation, Nasal cartilage loss | Altered Intercellular Communication | Biochemical markers indicative for autoinflammation and immunity (VICM, CRP, and CRPM), synovial inflammation (CIIIM), cartilage loss (CIIM), and bone degradation (CIM) were analyzed. | 25599306 |
| Pain Distress Question, Inflammation | Altered Intercellular Communication | DNA collected from saliva was genotyped for a priori selected genes involved with pain modulation (COMT and AVPR1A) and inflammation (IL1B and TNF/LTA). | 25599310 |
| Degenerative polyarthritis, Inflammation, Lower extremity pain | Altered Intercellular Communication | Osteoarthritis (OA) of the knee is a progressive disease that is associated with inflammation of the joints and lower extremity pain. | 25599456 |
| Inflammation | Altered Intercellular Communication | Oxidative stress resulting from the accumulation of ROS and/or defective removal of ROS by antioxidants has detrimental effects on cellular functions and may contribute to chronic inflammation. | 25599773 |
| Inflammation, Ulcerative Colitis | Altered Intercellular Communication | Although our data suggest that expression of the gene encoding p22phox is not associated with chronic inflammation in patients with UC, other mechanisms can affect oxidative stress in these patients. | 25599773 |
| Inflammation, Fibrosis Assessment, Substance, Hernia, Incisional hernia | Altered Intercellular Communication | Primitive hernia with loss of substance and big incisional hernia repair requires a prosthetic material which not induce, especially in the area of visceral peritoneal contact, chronic inflammation and fibrosis. | 25600559 |
| Inflammation, herpesvirus 1, human | Altered Intercellular Communication | Our clinical and microbiological data suggest that severe HSV-1 infection is the driver of periodontal inflammation in this case. | 25600604 |
| Refractory anemias, Inflammation | Altered Intercellular Communication | The contribution of patient-reported components to high DAS28 should inform decisions on disease-modifying or pain-management approaches in the treatment of RA when inflammation may be well controlled. | 25600850 |
| Liver parenchyma, Inflammation, Fibrosis Assessment, Intrahepatic Large Bile Duct, Hyperplasia | Altered Intercellular Communication | Histologic examination of resection specimens revealed markedly dilated large intrahepatic bile ducts with variable degrees of mural fibrosis, periductal gland hyperplasia, inflammation, and liver parenchymal atrophy. | 25600951 |
| Inflammation, Obesity | Altered Intercellular Communication | Long-term consumption of fatty foods is associated with obesity, macrophage activation and inflammation, metabolic imbalance, and a reduced lifespan. | 25601202 |
| Myelofibrosis, Bone Marrow | Altered Intercellular Communication | Assessment of bone marrow inflammation in patients with myelofibrosis: an 18F-fluorodeoxyglucose PET/CT study. | 25601337 |
| Myelofibrosis, Bone Marrow, Hematopoietic Neoplasms, Extramedullary Hematopoiesis Function | Altered Intercellular Communication | Myelofibrosis is a haematopoietic stem cell neoplasm characterized by bone marrow inflammation, reactive marrow fibrosis and extramedullary haematopoiesis. | 25601337 |
| Myelofibrosis, Bone Marrow | Altered Intercellular Communication | (18)F-FDG PET/CT is as a promising technique for the quantitation of bone marrow inflammation in myelofibrosis. | 25601337 |
| Atrophic, Inflammatory disease of mucous membrane | Altered Intercellular Communication | Atrophy was confined to the oxyntic mucosa in 10 patients, with intramucosal inflammation in a diffuse or basal-predominant pattern. | 25602795 |
| Inflammation, Depressed mood | Altered Intercellular Communication | C-reactive protein (CRP) is a heritable biomarker of systemic inflammation that is commonly elevated in depressed patients. | 25603415 |
| Impaired cognition, Pathology | Altered Intercellular Communication | Multivariable analyses adjusted for socio-demographic characteristics, smoking, ischemic pathologies, cognitive impairment and inflammation-related chronic pathologies. | 25603415 |
| Inflammation | Altered Intercellular Communication | It is thought that some of these preformed crystals within articular cartilage spill over into the joint space and trigger an acute attack of inflammation. | 25603588 |
| Inflammation, Calcifying Fibrous Pseudotumor | Altered Intercellular Communication | Surgical exploration revealed multiples solid nodules of the vaginal wall, with, at frozen section analysis, fibroblastic tissue, vessels and chronic inflammation without malignity, suggestive of fibrous pseudotumor of the tunica vaginalis. | 25603639 |
| Peripheral Arterial Diseases | Altered Intercellular Communication | Endothelial Cell Inflammation and Antioxidant Capacity are Associated With Exercise Performance and Microcirculation in Patients With Symptomatic Peripheral Artery Disease. | 25603804 |
| Inflammation, Peripheral Arterial Diseases | Altered Intercellular Communication | We determined whether exercise performance and lower extremity microcirculation were associated with endothelial cell inflammation, oxidative stress, and apoptosis and with circulating biomarkers of inflammation and antioxidant capacity in 160 patients with symptomatic peripheral artery disease (PAD). | 25603804 |
| Inflammation, Apolipoprotein E | Altered Intercellular Communication | Apolipoprotein E promotes subretinal mononuclear phagocyte survival and chronic inflammation in age-related macular degeneration. | 25604058 |
| Inflammation | Altered Intercellular Communication | Our results underline the inflammatory role of APOE in sterile inflammation in the immunosuppressive subretinal space. | 25604058 |
| methyldopa, Inflammation | Altered Intercellular Communication | They provide rationale for the implication of IL-6 in AMD and open avenues toward therapies inhibiting pathogenic chronic inflammation in late AMD. | 25604058 |
| Coinfection, Inflammation, Hepatitis C | Altered Intercellular Communication | Notably, the levels of immune activation and inflammation in patients with previous VL were not related to the time of VL diagnosis, the number of VL relapses, or hepatitis C virus (HCV) coinfection. | 25604328 |
| Inflammation, Takayasu Arteritis | Altered Intercellular Communication | Th1 and Th17 cytokines drive inflammation in Takayasu arteritis. | 25604824 |
| vascular inflammations | Altered Intercellular Communication | The nature of the T cells driving vascular inflammation and the effects of glucocorticoids on the systemic components of TAK are not understood. | 25604824 |
| Inflammation, Breast Carcinoma | Altered Intercellular Communication | Chronic inflammation may be related to breast cancer risk through a mechanism involving the percent of breast area that is dense (percent MD). | 25604866 |
| Inflammation, Pulmonary Fibrosis | Altered Intercellular Communication | Hypoxic epithelial necrosis triggers neutrophilic inflammation via IL-1 receptor signaling in cystic fibrosis lung disease. | 25607238 |
| Inflammation, Hypoxia, Cystic Fibrosis | Altered Intercellular Communication | Although hypoxia is common in airways from patients with cystic fibrosis (CF), its role in neutrophilic inflammation remains unknown. | 25607238 |
| Inflammation, Airway Obstruction, Necrosis | Altered Intercellular Communication | We recently demonstrated that hypoxic epithelial necrosis caused by airway mucus obstruction precedes neutrophilic inflammation in Scnn1b-transgenic (Scnn1b-Tg) mice with CF-like lung disease. | 25607238 |
| Airway structure, Obstruction, Lung diseases, Necrosis | Altered Intercellular Communication | To determine the role of epithelial necrosis and IL-1R signaling in the development of neutrophilic airway inflammation, mucus obstruction, and structural lung damage in CF lung disease. | 25607238 |
| airway disease, Inflammation, Bacterial Infections | Altered Intercellular Communication | Our results support an important role of hypoxic epithelial necrosis in the pathogenesis of neutrophilic inflammation independent of bacterial infection and suggest IL-1R as a novel target for antiinflammatory therapy in CF and potentially other mucoobstructive airway diseases. | 25607238 |
| Inflammation, Periodontitis, Diabetes Mellitus, diabetic | Altered Intercellular Communication | There is scientific data to support the existence of a two-way relationship between diabetes and periodontitis, with diabetes increasing the risk for periodontitis, and periodontal inflammation negatively affecting the diabetic status. | 25607396 |
| Peritonitis, Acute appendicitis NOS (disorder), Gastrointestinal Hemorrhage, Diverticulitis, Intestinal Obstruction, Hernia, Inguinal | Altered Intercellular Communication | Of the 29 S MD cases, 14 had intestinal obstruction, seven cases showed lower gastrointestinal bleeding, five cases presented acute inflammation (diverticulitis) and three cases were complicated with peritonitis; 15 cases of AS MD were discovered during surgical interventions for acute appendicitis (14 cases) or inguinal hernia (one case). | 25607401 |
| ARCN1 gene, Pulmonary Emphysema, Airway structure | Altered Intercellular Communication | High-resolution computed tomography (HRCT) phenotypes of COPD may reflex the pathological basis of COPD indirectly by evaluating the small airway inflammation and emphysema. | 25607515 |
| Dermatitis | Altered Intercellular Communication | Preclinical mouse studies have demonstrated efficacy of abobotulinumtoxinA in improving psoriasiform skin inflammation. | 25607710 |
| Inflammation, Biliary calculi | Altered Intercellular Communication | In conjunction with the patient's history of laparoscopic cholecystectomy 1 year prior, the findings were consistent with inflammation around a migrated subdiaphragmatic gallstone. | 25608158 |
| Communicable Diseases, Inflammation | Altered Intercellular Communication | A similar pattern is noted for inflammation (N = 3,537, 78%), infection (N = 2,451, 54%) and injury (N = 3,401, 75%). | 25608728 |
| Neuralgia | Altered Intercellular Communication | Our investigation revealed a clear shift of T-cell subsets towards anti-inflammation in patients with neuropathic pain. | 25608762 |
| malignant disease, Granulomatous inflammation | Altered Intercellular Communication | Our results show that great caution should be exercised when evaluating FDG-avid PET-CT nodes in patients with known malignant disease, as a significant proportion of these lesions may be benign, particularly in geographic locations with a high background prevalence of granulomatous inflammation. | 25608976 |
| Hyperlipidemia, Rheumatoid Arthritis, Inflammation, Coronary heart disease | Altered Intercellular Communication | Association of hyperlipidaemia, inflammation and serological status and coronary heart disease among patients with rheumatoid arthritis: data from the National Veterans Health Administration. | 25609412 |
| Inflammation, Refractory anemias, Coronary heart disease, Cerebrovascular accident, Rheumatoid Arthritis, Choline Dehydrogenase, Mitochondrial | Altered Intercellular Communication | To examine the association of serum lipids, inflammation and seropositivity on coronary heart disease (CHD) and stroke in patients with rheumatoid arthritis (RA). | 25609412 |
| Refractory anemias, Inflammation, Cerebrovascular accident, Choline Dehydrogenase, Mitochondrial | Altered Intercellular Communication | CRP and ESR were similarly associated with increase MI risk and stroke, reflecting the prominent role of inflammation in CHD risk in RA. | 25609412 |
| Inflammation, Metabolic Diseases, Obesity | Altered Intercellular Communication | Accurate identification of obesity, systemic inflammation, and atherogenic lipid profile is key to assessing the risk of cardiometabolic diseases. | 25609936 |
| Inflammation, Malignant Neoplasms | Altered Intercellular Communication | C-reactive protein (CRP) is a marker of systemic inflammation that has been associated with the incidence and prognosis for a number of different cancers. | 25613115 |
| Malignant neoplasm of liver, Inflammation, Hepatobiliary Disorder | Altered Intercellular Communication | Our findings suggest that levels of systemic inflammation may serve as a long-term marker of liver cancer and liver disease. | 25613115 |
| Inflammation, Brain Injuries | Altered Intercellular Communication | Levels of LBP, Il-10, IL-6 and CRP, as well as S100B, were measured as markers of inflammation and brain damage by commercially available immunometric tests. | 25613713 |
| Inflammation | Altered Intercellular Communication | Our data show that blood levels of inflammation markers may be used as early predictors of stroke-associated infection. | 25613713 |
| Inflammation, Primary malignant neoplasm, Malnutrition, Fatigue | Altered Intercellular Communication | Is glutamine deficiency the link between inflammation, malnutrition, and fatigue in cancer patients? | 25614125 |
| Inflammation, Primary malignant neoplasm, Neoplasms, Fatigue | Altered Intercellular Communication | Evaluation of potential associations between plasma glutamine levels and the incidence of cancer related fatigue, physical performance, poor nutritional status, and inflammation in patients with solid tumors. | 25614125 |
| Inflammation, Primary malignant neoplasm, Malnutrition, Fatigue | Altered Intercellular Communication | The data support our working hypothesis that in cancer patients systemic inflammation maintains a catabolic situation leading to malnutrition symptoms and glutamine deprivation, the latter being associated with cancer related fatigue. | 25614125 |
| Airway structure | Altered Intercellular Communication | Ceramide-1-phosphate inhibits cigarette smoke-induced airway inflammation. | 25614161 |
| Pulmonary Emphysema, Pneumonitis | Altered Intercellular Communication | We aimed to clarify the role of C1P in the pathogenesis of CS-triggered pulmonary inflammation and emphysema in humans and mice. | 25614161 |
| Pulmonary Emphysema, Acute and chronic inflammation | Altered Intercellular Communication | C1P reduced CS-induced acute and chronic lung inflammation and development of emphysema in mice, which was associated with a reduction in nSMase and NF-kB activity in the lungs. | 25614161 |
| Pneumonitis | Altered Intercellular Communication | Our results suggest that C1P is a potential target for anti-inflammatory treatment in CS-induced lung inflammation. | 25614161 |
| Granulomatous inflammation | Altered Intercellular Communication | Pathologist awareness of this rare cause of granulomatous inflammation aids recognition of BCG-osis and facilitates prompt initiation of antimycobacterial therapy. | 25614462 |
| Inflammation, Atherosclerosis | Altered Intercellular Communication | Inflammation, endothelial activation and oxidative stress have been established as key events in the initiation and progression of atherosclerosis. | 25614985 |
| Inflammation, Atherosclerosis, Coronary heart disease | Altered Intercellular Communication | High-density lipoprotein cholesterol (HDL-c) is protective against atherosclerosis and coronary heart disease, but its association with inflammation, endothelial activation and oxidative stress is not well established. | 25614985 |
| Inflammation | Altered Intercellular Communication | Subjects with low HDL-c had greater concentrations of inflammation, endothelial activation and oxidative stress biomarkers compared to controls. | 25614985 |
| Inflammation, Atherosclerosis | Altered Intercellular Communication | It is also an independent predictor for enhanced inflammation and endothelial activation, which are pivotal in the pathogenesis of atherosclerosis and atherosclerosis-related complications. | 25614985 |
| Inflammation, Acute Coronary Syndrome | Altered Intercellular Communication | No association between vitamin D levels and inflammation markers in patients with acute coronary syndrome. | 25615956 |
| Inflammation, GDC AJCC Clinical Stage Terminology | Altered Intercellular Communication | This study demonstrates that calcidiol levels are not associated with the inflammation markers in patients with acute phase ACS. | 25615956 |
| Inflammation, Observation Method - Coagulation, Atherosclerosis | Altered Intercellular Communication | Markers of inflammation and coagulation after long-term exposure to coarse particulate matter: a cross-sectional analysis from the multi-ethnic study of atherosclerosis. | 25616153 |
| Inflammation, Observation Method - Coagulation, Atherosclerosis | Altered Intercellular Communication | Here we examine long-term associations with inflammation and coagulation in the Multi-Ethnic Study of Atherosclerosis. | 25616153 |
| Inflammation, Observation Method - Coagulation | Altered Intercellular Communication | Our cross-sectional analysis provided some evidence that long-term PM10-2.5 exposure was associated with inflammation and coagulation, but associations were modest and depended on particle composition. | 25616153 |
| Inflammation | Altered Intercellular Communication | Specialized proresolving mediators (SPMs) induce resolution of inflammation. | 25616438 |
| Alzheimers Disease", Inflammation, Data types - Address | Altered Intercellular Communication | Alzheimer's disease (AD) is associated with brain inflammation and reduced levels of SPMs. | 25616438 |
| Inflammation, Osteoporosis, Atherosclerosis | Altered Intercellular Communication | Elevated plasma DMG levels are associated with atherosclerotic cardiovascular disease and inflammation, which in turn are related to osteoporosis. | 25616506 |
| Arterial Stiffness, Inflammation, Carotid Intima-Media Thickness, Atherosclerosis | Altered Intercellular Communication | Atherosclerosis was evaluated by assessing carotid intima-media thickness by ultrasound, arterial stiffness by Young's modulus and inflammation by C-reactive protein. | 25616705 |
| Arterial Stiffness, Inflammation, Diabetes Mellitus | Altered Intercellular Communication | Serum levels of methylglyoxal-derived hydroimidazolone-1 in diabetes patients are increased and associated with low-grade inflammation, but not yet arterial stiffness or wall thickness. | 25616705 |
| Airway structure | Altered Intercellular Communication | Vitamin D reduces eosinophilic airway inflammation in nonatopic asthma. | 25617224 |
| Airway structure | Altered Intercellular Communication | Vitamin D supplementation reduced eosinophilic airway inflammation in patients with nonatopic asthma with severe eosinophilic airway inflammation, but did not affect sputum neutrophils. | 25617224 |
| Inflammation, Primary malignant neoplasm | Altered Intercellular Communication | The neutrophil-to-lymphocyte ratio (NLR), an easily determinable marker of systemic inflammation, has been associated with clinical outcome in various cancer entities. | 25617235 |
| Inflammation | Altered Intercellular Communication | Adjuvant treatment with crude rhubarb for patients with systemic inflammation reaction syndrome/sepsis: a meta-analysis of randomized controlled trials. | 25617260 |
| Inflammation, Obesity | Altered Intercellular Communication | In addition to its important role as marker of iron stores, serum ferritin is a marker of systemic inflammation, and obesity has been associated with chronic inflammation. | 25617548 |
| Neurodegenerative Disorders, Inflammation | Altered Intercellular Communication | The diagnosis can be easily mistaken for other neurodegenerative diseases, which are often accompanied by inflammation and the production of cytokines. | 25617881 |
| Inflammation, Cardiovascular Diseases | Altered Intercellular Communication | Wholegrain (WG) consumption is associated with reduced risk of cardiovascular disease, but clinical data on inflammation and immune function is either conflicting or limited. | 25618418 |
| Inflammation, Neoplasms | Altered Intercellular Communication | C-reactive protein (CRP) is a sensitive marker of inflammation that has been linked with prognosis in various solid tumours. | 25618827 |
| Inflammation, "Alzheimers Disease", Data types - Address | Altered Intercellular Communication | The impact of inflammation suppressor pathways on Alzheimer's disease (AD) evolution remains poorly understood. | 25619654 |
| Neoplasms, Lymphoma, Conjunctivitis | Altered Intercellular Communication | In three patients a conjunctival tumor of unknown origin, in one case each a papillomatous alteration of the conjunctiva, a conjunctival granulomatous inflammation, and a lymphoma were assumed respectively. | 25619666 |
| Inflammation, Electrocardiogram: myocardial infarction (finding), Venous Stroke, Corneal Endothelial Cell Loss | Altered Intercellular Communication | The aim of our study was to characterize and compare the short- and long-term mobilization of endothelial progenitor cells and circulating endothelial cells after acute myocardial infarction or atherothrombotic stroke, and to determine the relationship between these cell counts and plasma concentrations of vascular cell adhesion molecule (VCAM-1) and Von Willebrand factor (VWF) as surrogate markers of endothelial damage and inflammation. | 25619946 |
| Inflammation, Neoplasms, Malignant Neoplasms | Altered Intercellular Communication | Pentraxin-3 (PTX3), a modulator of tumor-associated inflammation, is known to be positively correlated with tumor grade and severity of malignancies, but the function and molecular underlying mechanisms of PTX3 remain unclear. | 25620175 |
| Communicable Diseases, Inflammation | Altered Intercellular Communication | Both features were attributed to a chronic inflammation because of an abscess in the right iliopsoas caused by infection due to bilateral hip replacement which underwent revision surgery. | 25621695 |
| Inflammation, Necrosis | Altered Intercellular Communication | Pathomorphological examination of the testicular tissue revealed focal necrosis and diffuse suppurative inflammation of the testicular tunic. | 25623185 |
| Cessation of life, Communicable Diseases, Inflammation, Bacterial Infections | Altered Intercellular Communication | In noninfectious causes of death with decomposition, postmortem investigations failed to reveal results consistent with generalized inflammation or bacterial infections at the time of death. | 25623190 |
| Inflammation, Demographics Domain, Cardiovascular Diseases | Altered Intercellular Communication | POD has been associated with systemic inflammation, a known risk factor for cardiovascular and bone disease, both of which are more common in patients with DM. | 25623292 |
| Inflammation, Complication Aspects | Altered Intercellular Communication | However, there is mixed evidence that treatment of POD reduces inflammation, improves DM control, and reduces DM complications. | 25623292 |
| Inflammation | Altered Intercellular Communication | Clinical evaluation and assessment of synovial inflammation by contrast-enhanced ultrasound (CEUS). | 25623520 |
| Inflammation, Arthritis, Psoriatic | Altered Intercellular Communication | Despite the efficacy of TNF inhibitors, most patients with psoriatic arthritis maintain a residual synovial inflammation. | 25623520 |
| Inflammation | Altered Intercellular Communication | The secondary outcome was to assess synovial inflammation in hand joints detected by contrast-enhanced ultrasound. | 25623520 |
| Inflammation | Altered Intercellular Communication | Synovial inflammation detected by contrast-enhanced ultrasound, analysed by a software system, was also assessed. | 25623520 |
| Inflammation, Hemophilic arthropathy, Congenital Abnormality | Altered Intercellular Communication | Point-of-care musculoskeletal ultrasound is critical for the diagnosis of hemarthroses, inflammation and soft tissue abnormalities in adult patients with painful haemophilic arthropathy. | 25623830 |
| Inflammation, Hemophilia A, Congenital Abnormality | Altered Intercellular Communication | Using high resolution MSKUS, employing grey scale and power Doppler, we sought to retrospectively (i) investigate soft tissue abnormalities in painful haemophilic joints and (ii) to determine to what extent MSKUS findings, functional or radiographic joint scores correlate with biomarkers of inflammation in PWH. | 25623830 |
| Tendinitis, Inflammation, Synovitis, Bursitis, Enthesitis | Altered Intercellular Communication | The most prominent findings (66.5%) pertained to inflammatory soft tissue changes including synovitis, tendinitis, enthesitis, bursitis and fat pad inflammation. | 25623830 |
| Data types - Address | Altered Intercellular Communication | The human butyrylcholinesterase (BChE) is an enzyme that has specific roles in cholinergic neurotransmission and it has been associated with AD. | 25624079 |
| Asthma, Sinusitis, Chronic sinusitis | Altered Intercellular Communication | Sinus and adenoid inflammation in children with chronic rhinosinusitis and asthma. | 25624129 |
| airway disease, Paranasal Sinus Disorder, Airway structure, Asthma, asthma chronic | Altered Intercellular Communication | This observation is consistent with the hypothesis that asthma in these patients is caused or exacerbated by severe upper airway disease and supports the concept that treating sinus disease is paramount in the management of chronic asthma in children using, for the first time, direct measurements of airway inflammation in children. | 25624129 |
| Inflammation, Asthma | Altered Intercellular Communication | Leukotriene B4 (LTB4) is an important disease marker, but its role in inflammation of the small airways in asthma has not been established yet. | 25624130 |
| IL13 gene | Altered Intercellular Communication | Allergic rhinitis (AR) is an inflammatory condition of the nasal mucosa characterized by symptoms of nasal discharge, itching, sneezing, and congestion. | 25624132 |
| Inflammation | Altered Intercellular Communication | Although rectal inflammation was detected, no polyps were found in the rectum. | 25624746 |
| Inflammation, Coronary Artery Disease, Atherosclerosis | Altered Intercellular Communication | Abnormal blood rheology and chronic low grade inflammation: possible risk factors for accelerated atherosclerosis and coronary artery disease in Lewis negative subjects. | 25626016 |
| Inflammation, Precocious atherosclerosis | Altered Intercellular Communication | To test the hypothesis that abnormal hemorheology and chronic low-grade inflammation are more prevalent in Lewis negative individuals, possibly contributing to premature atherosclerosis. | 25626016 |
| Inflammation, Leukocytes | Altered Intercellular Communication | However, markers of inflammation (WBC, hs-CRP, ESR) were significantly elevated and rheological parameters (RBC aggregation, plasma viscosity) were abnormal in Lewis negative subjects, especially when compared to the Le(a-b+) group. | 25626016 |
| Autoimmune Diseases, Inflammation, Primary malignant neoplasm | Altered Intercellular Communication | Aberrant RIG-I signaling leads to inflammation, autoimmune diseases and cancer. | 25626059 |
| Inflammation, Pathology, Edema | Altered Intercellular Communication | Ultrasound is useful for non-invasive visualization of focal nerve pathologies probably resulting from demyelination, remyelination, edema or inflammation. | 25626722 |
| Inflammation | Altered Intercellular Communication | Surgery induces inflammation and pro-inflammatory cytokines are associated with post-operative complications. | 25626738 |
| Inflammation, Fibrosis Assessment | Altered Intercellular Communication | Rho kinase (ROCK) is associated with VEGF-driven angiogenesis, as well as with inflammation and fibrosis. | 25626969 |
| Inflammation, Fibrosis Assessment | Altered Intercellular Communication | Outcome was assessed by analysis of inflammation (CD45), angiogenesis (FITC-dextran), vessel leakage (Texas Red-conjugated Dextran and FITC-labeled lectin) and fibrosis (Sirius Red/Collagen I). | 25626969 |
| Inflammation, Fibrosis Assessment | Altered Intercellular Communication | 05), whereas DC101 had no effect on inflammation nor on fibrosis. | 25626969 |
| Inflammation, Fibrosis Assessment | Altered Intercellular Communication | The results suggest that targeting ROCK with AMA0428 not only reduces neoangiogenesis, but also blocks inflammation and fibrosis (contrary to VEGF suppression). | 25626969 |
| Inflammation, Fibrosis Assessment | Altered Intercellular Communication | Gene and protein expressions related to fibrosis, inflammation, and chondrogenesis were analyzed by quantitative reverse transcription-polymerase chain reaction and immunohistochemistry. | 25627290 |
| Inflammation | Altered Intercellular Communication | Symptoms caused by this pathogen are accompanied by intense local and systemic inflammation. | 25627751 |
| Airway structure, Nose symptoms | Altered Intercellular Communication | Mucociliary clearance, airway inflammation and nasal symptoms in urban motorcyclists. | 25628001 |
| Airway structure | Altered Intercellular Communication | There is evidence that outdoor workers exposed to high levels of air pollution exhibit airway inflammation and increased airway symptoms. | 25628001 |
| Inflammation, Traumatic injury | Altered Intercellular Communication | We suggest that these findings may be used to develop new therapeutics to treat the devastating inflammation and cell destruction evoked by CNS injuries. | 25628216 |
| Inflammation, Granulation finding | Altered Intercellular Communication | Histological and immunohistochemical examinations of the resected and infarcted neonatal hearts revealed inflammation and granulation tissue formation. | 25628406 |
| Inflammation, Postoperative Period | Altered Intercellular Communication | Changes in the Concentrations of Mediators of Inflammation and Oxidative Stress in Exhaled Breath Condensate During Liver Transplantation and Their Relations With Postoperative ARDS. | 25628453 |
| eosinophil | Altered Intercellular Communication | Wogonin induces eosinophil apoptosis and attenuates allergic airway inflammation. | 25629436 |
| eosinophil, allergic inflammation | Altered Intercellular Communication | To investigate the ability of the flavone wogonin to induce eosinophil apoptosis in vitro and attenuate eosinophil-dominant allergic inflammation in vivo in mice. | 25629436 |
| Pneumonitis | Altered Intercellular Communication | Allergic lung inflammation was modeled in mice sensitized and challenged with ovalbumin. | 25629436 |
| eosinophil, Respiratory Hypersensitivity | Altered Intercellular Communication | Wogonin administration attenuated allergic airway inflammation in vivo with reductions in BAL and interstitial eosinophil numbers, increased eosinophil apoptosis, reduced airway mucus production, and attenuated airway hyperresponsiveness. | 25629436 |
| eosinophil, allergic inflammation | Altered Intercellular Communication | Wogonin induces eosinophil apoptosis and attenuates allergic airway inflammation, suggesting that it has therapeutic potential for the treatment of allergic inflammation in humans. | 25629436 |
| Communicable Diseases, Inflammation | Altered Intercellular Communication | However, fracture-related inflammation can make investigations used in the diagnosis of infection less reliable. | 25631172 |
| Inflammation, One Vessel Coronary Disease | Altered Intercellular Communication | We investigated the association between circulating biomarkers of inflammation and MRI markers of small vessel disease. | 25632086 |
| Inflammation, Cerebral Infarction, Hemorrhagic, Tumor necrosis, Cerebral Small Vessel Diseases, Cerebral microbleeds, vascular inflammations | Altered Intercellular Communication | We performed a cross-sectional study relating a panel of 15 biomarkers, representing systemic inflammation (high-sensitivity C-reactive protein, interleukin-6, monocyte chemotactic protein-1, tumor necrosis factor a, tumor necrosis factor receptor 2, osteoprotegerin, and fibrinogen), vascular inflammation (intercellular adhesion molecule 1, CD40 ligand, P-selectin, lipoprotein-associated phospholipase A2 mass and activity, total homocysteine, and vascular endothelial growth factor), and oxidative stress (myeloperoxidase) to ischemic (white matter hyperintensities/silent cerebral infarcts) and hemorrhagic (cerebral microbleeds) markers of cerebral small vessel disease (CSVD) on MRI in 1,763 stroke-free Framingham offspring (mean age 60.2 +- 9.1 years, 53.7% women). | 25632086 |
| Inflammation, Hemorrhagic | Altered Intercellular Communication | Our study supports a possible role for inflammation in the pathogenesis of CSVD, but suggests that differing inflammatory pathways may underlie ischemic and hemorrhagic subtypes. | 25632086 |
| Airway structure, Cystic Fibrosis | Altered Intercellular Communication | Patients with cystic fibrosis (CF) lung disease have chronic airway inflammation driven by disrupted balance of T-cell (Th17 and Th2) responses. | 25632992 |
| Inflammation, Infectious Lung Disorder | Altered Intercellular Communication | Modulation of Tregs represents a novel strategy to rebalance T-cell responses, dampen inflammation, and ultimately improve outcomes for patients with infective CF lung disease. | 25632992 |
| Inflammation, ETV3 wt Allele | Altered Intercellular Communication | Higher MMP-8 in MetS is possibly mediated through mechanisms both dependent and independent of chronic low grade inflammation. | 25633268 |
| Dental Plaque, CEL gene | Altered Intercellular Communication | The fibroblast activation protein alpha (FAP) was recently proposed as inflammation-induced protease involved in the process of plaque vulnerability. | 25633335 |
| Inflammation, Diabetes Mellitus, Non-Insulin-Dependent, Chronic Kidney Diseases | Altered Intercellular Communication | Effect of paricalcitol on endothelial function and inflammation in type 2 diabetes and chronic kidney disease. | 25633573 |
| Inflammation | Altered Intercellular Communication | Vitamin D and its analogs may play a role in regulation of endothelial function and inflammation. | 25633573 |
| Alzheimers Disease", Neurotoxicity Syndromes, Data types - Address | Altered Intercellular Communication | This excitatory neurotransmitter is thought to contribute to neurotoxicity in neurodegenerative conditions such as Alzheimer's disease (AD) but the expression of hBCAT in this disease has not previously been investigated. | 25633671 |
| Pneumonitis | Altered Intercellular Communication | Microinhalation of gastric secretions might induce lung inflammation leading to OP and relapse. | 25633753 |
| Gastrointestinal inflammation | Altered Intercellular Communication | The development of MC is often associated with intestinal inflammation and/or microsatellite instability (MSI). | 25634199 |
| Gastrointestinal inflammation | Altered Intercellular Communication | Intestinal inflammation due to IS occurs by the destruction of colonic microvilli and induces chronic diarrhea. | 25634199 |
| Gastrointestinal inflammation | Altered Intercellular Communication | It seemed that the cause of MC development was not MSI but intestinal inflammation. | 25634199 |
| Gastrointestinal inflammation, Neoplasms | Altered Intercellular Communication | This report provides evidence for an association between neoplasm and IS-induced intestinal inflammation. | 25634199 |
| Granulomatous inflammation | Altered Intercellular Communication | From 83 fine-needle aspiration (FNA) specimens, 54.8% (40/73) showed granulomatous inflammation, 62.5% (40/64) had positive mycobacterial culture, and 73.3% (11/15) tested positive with Xpert MTB/RIF (Cepheid, Sunnyvale, CA). | 25634205 |
| Granulomatous inflammation | Altered Intercellular Communication | From 62 biopsy samples, 96.8% (60/62) showed granulomatous inflammation, 64.6% (31/48) had positive mycobacterial culture, and 46.1% (6/13) tested positive with Xpert MTB/RIF. | 25634205 |
| Conjunctivitis, Allergic Conjunctivitis | Altered Intercellular Communication | Clinical characteristics associated with conjunctival inflammation in allergic rhinoconjunctivitis. | 25634218 |
| Conjunctivitis, Radiation Arc | Altered Intercellular Communication | The cytological characteristics of conjunctival inflammation in patients with ARC were assessed and then correlated to clinical characteristics. | 25634218 |
| Inflammation, Nasal inflammation | Altered Intercellular Communication | Patients were subdivided into 3 groups on the basis of cytological phenotype: (1) nasal and conjunctival inflammation, (2) nasal inflammation only, and (3) no mucosal inflammation. | 25634218 |
| Conjunctivitis | Altered Intercellular Communication | Male sex (odds ratio, 8.4; P = .005) and eye itching (odds ratio, 1.3; P = .019) significantly correlated with conjunctival inflammation. | 25634218 |
| Conjunctivitis | Altered Intercellular Communication | The odds of exhibiting conjunctival inflammation, at multivariate analysis, increased 13-fold for men and 1.5-fold for each point on the eye itching scale. | 25634218 |
| Conjunctivitis | Altered Intercellular Communication | A cutoff value of 3 or more for eye itching effectively identified patients with conjunctival inflammation. | 25634218 |
| Radiation Arc, Conjunctivitis | Altered Intercellular Communication | Our study demonstrates that some clinical manifestations of ARC correlate well with conjunctival inflammation. | 25634218 |
| Inflammation, Parkinsonian Disorders | Altered Intercellular Communication | Inflammation mediated by inducible nitric oxide synthase may possibly contribute to the association between welding fume and parkinsonism, but requires verification in a longitudinal study. | 25634431 |
| Inflammation, Hemorrhage | Altered Intercellular Communication | The incidence of delayed complications was 1.6 per 1000 procedures (95% confidence interval, 0.3-3.0), which comprised five post-polypectomy bleeds and one post-polypectomy inflammation. | 25634931 |
| Inflammation | Altered Intercellular Communication | C1q/TNF-related protein 1 (CTRP-1), a novel adipocyte factor, may participate in the mechanisms of metabolism and inflammation. | 25635749 |
| Inflammation, Choline Dehydrogenase, Mitochondrial, Atherosclerosis | Altered Intercellular Communication | The variation of plasma CTRP-1 and IL-6 concentrations may play an important role in reflecting the degree of inflammation in CHD and the severity of coronary arterial atherosclerosis. | 25635749 |
| Inflammation, Pancreatic Ductal Adenocarcinoma, Diabetes Mellitus | Altered Intercellular Communication | Analysis of global gene expression profiles suggests a role of acute inflammation in type 3C diabetes mellitus caused by pancreatic ductal adenocarcinoma. | 25636208 |
| Inflammation, Fibrosis Assessment, Chronic liver disease, Lymphoproliferative Disorder of the Skin | Altered Intercellular Communication | Angiogenesis and inflammation have been involved in the progression of fibrosis in patients with chronic liver disease (CLD). | 25636502 |
| Pain Distress Question, Inflammation, Neuralgia | Altered Intercellular Communication | MicroRNAs are found to be involved in the generation and maintenance of pain in animal models of inflammation and neuropathic pain. | 25636687 |
| Refractory anemias, Inflammation, Disease | Altered Intercellular Communication | Our findings show substantial detrimental role of exposure to RA flare and cumulative burden of RA disease severity in CVD risk in RA, suggesting important cardiovascular benefits associated with tight inflammation control and improved flare management in patients with RA. | 25637001 |
| Inflammatory abnormality of the eye | Altered Intercellular Communication | Mean BCVA at the onset of ocular inflammation was 0.253 +- 0.424. | 25637181 |
| Inflammatory abnormality of the eye | Altered Intercellular Communication | Mean BCVA after treatment was 0.036 +- 0.242, significantly better than at the onset of ocular inflammation (P < .05). | 25637181 |
| Syphilitic, Inflammatory abnormality of the eye | Altered Intercellular Communication | Retrospective, descriptive and non-comparative study of a series of patients hospitalized between 2007 and 2013 in our department of ophthalmology for management of ocular inflammation associated with a positive syphilitic serology. | 25637233 |
| Inflammatory abnormality of the eye | Altered Intercellular Communication | Every structure of the eye may be involved with syphilis; therefore, syphilis must be systematically sought during the etiologic assessment of ocular inflammation even in the absence of historical risk factors. | 25637233 |
| Inflammation, Rheumatoid Arthritis | Altered Intercellular Communication | The association between reduction in inflammation and changes in lipoprotein levels and HDL cholesterol efflux capacity in rheumatoid arthritis. | 25637346 |
| Inflammation | Altered Intercellular Communication | Patients with bacterial LRTI showed significant overexpression of inflammation and neutrophil genes (bacterial > bacterial-viral > viral), and those with viral LRTI displayed significantly greater overexpression of interferon genes (viral > bacterial-viral > bacterial). | 25637350 |
| Inflammation | Altered Intercellular Communication | In comparison with both control and HTN(-)HFpEF, patients with HTN(+)HFpEF had increased left ventricular end-diastolic pressure, left atrial volume, N-terminal propeptide of brain natriuretic peptide, total, collagen-dependent, and titin-dependent stiffness, insoluble collagen, increased titin phosphorylation on PEVK S11878(S26), reduced phosphorylation on N2B S4185(S469), and increased biomarkers of inflammation. | 25637629 |
| Inflammation | Altered Intercellular Communication | Aging is associated with an increase in a chronic, low-grade inflammation. | 25638154 |
| Inflammation, Chronic disease, Heavy Chain Disease | Altered Intercellular Communication | Our findings also suggest a possibility that systemic inflammation associated with chronic diseases may explain accelerated aging phenomenon previously observed among the patients with heavy disease burden. | 25638154 |
| Inflammation, Pulmonary Emphysema | Altered Intercellular Communication | Lactosylceramide-accumulation in lipid-rafts mediate aberrant-autophagy, inflammation and apoptosis in cigarette smoke induced emphysema. | 25638276 |
| Inflammation, Nasal sinus, Odontogenic Cysts | Altered Intercellular Communication | The most common cause of unilateral paranasal sinusitis was odontogenic infection, as seen in 138 cases (72.6%), followed by chronic inflammation in 43 cases (22.6%). | 25638394 |
| Sepsis, Inflammation | Altered Intercellular Communication | IL-17 was helpful for inflammation in severe sepsis. | 25638510 |
| Sarcoidosis | Altered Intercellular Communication | Rarely, it can be caused by systemic inflammatory conditions such as sarcoidosis. | 25638512 |
| Inflammation, Vitreous opacities | Altered Intercellular Communication | On presentation, diffuse keratic precipitates, anterior chamber inflammation and snowball-like vitreous opacity were observed. | 25639036 |
| Inflammation, Arthrodermataceae, Bryozoa | Altered Intercellular Communication | Anthropophilic dermatophytes resulted in a score of 1.82 points for the severity of inflammation and a score of 1.84 points for the extent of lesions while zoophilic dermatophytes resulted in a score of 2.14 points for the severity of inflammation and a score of 1.50 points for the extent of lesions. | 25639303 |
| Inflammation, Chronic sinusitis | Altered Intercellular Communication | Level of secreted HMGB1 correlates with severity of inflammation in chronic rhinosinusitis. | 25639490 |
| Inflammation, Chronic sinusitis | Altered Intercellular Communication | The purpose of this study was to determine the relationship between the HMGB1 level in nasal secretions and the severity of inflammation in chronic rhinosinusitis. | 25639490 |
| Inflammation, Chronic sinusitis | Altered Intercellular Communication | Our results showed that HMGB1 is secreted into the extracellular area space in the upper airway, and HMGB1 levels in nasal lavage fluid correlate with severity of inflammation, as assessed by the Lund-Mackay staging system for chronic rhinosinusitis. | 25639490 |
| Inflammation | Altered Intercellular Communication | Inflammation can cause endoplasmic reticulum (ER) stress and therefore activates the unfolded protein response (UPR). | 25640174 |
| Inflammation | Altered Intercellular Communication | These findings suggest that MANF may be a negative regulator of inflammation and mediate the crosstalk between the NF-kB pathway and ER stress. | 25640174 |
| Inflammation | Altered Intercellular Communication | Further experiments reveal the possible mechanisms for the anti-calcification of PC crosslinking including (1) inhibiting inflammation cell attachment, and secretion of inflammatory factors such as MMPs and TNF-a, (2) preventing elastin degradation by elastase, and (3) direct inhibition of mineral nucleation in elastin. | 25641644 |
| Inflammation, Pancreatic Ductal Adenocarcinoma | Altered Intercellular Communication | Cancer-associated inflammation is a key molecular feature of pancreatic ductal adenocarcinoma. | 25641673 |
| Celiac Disease, Malabsorption Syndrome, Gastrointestinal inflammation | Altered Intercellular Communication | Celiac disease, characterized by intestinal inflammation and malabsorption, occurs in 1 per cent of the population and is often undiagnosed. | 25642877 |
| Inflammation | Altered Intercellular Communication | Bonar scores and synovial inflammation grade were checked 5 weeks after the injection. | 25643855 |
| prostatitis | Altered Intercellular Communication | Smoking Is Associated with Acute and Chronic Prostatic Inflammation: Results from the REDUCE Study. | 25644151 |
| prostatitis | Altered Intercellular Communication | As prostate inflammation is common, we hypothesized smoking could contribute to prostate inflammation. | 25644151 |
| prostatitis | Altered Intercellular Communication | Prostate inflammation was assessed by systematic central review blinded to smoking status. | 25644151 |
| Chronic inflammation | Altered Intercellular Communication | In contrast, current smoking was linked with chronic inflammation in the baseline biopsy, but not at 2- and 4-year biopsies. | 25644151 |
| prostatitis | Altered Intercellular Communication | Acute and chronic prostate inflammations were identified in 1,261 (15%) and 6,352 (78%) baseline biopsies, respectively. | 25644151 |
| prostatitis | Altered Intercellular Communication | In conclusion, among men undergoing prostate biopsy, current smoking was independently associated with acute and possibly chronic prostate inflammations. | 25644151 |
| Inflammatory abnormality of the eye | Altered Intercellular Communication | The main outcome measures were control of ocular inflammation, progression of disease, and surgical success. | 25644537 |
| Inflammatory abnormality of the eye | Altered Intercellular Communication | Control of ocular inflammation before lid surgery was achieved in all cases. | 25644537 |
| Inflammation, Non-alcoholic Fatty Liver Disease | Altered Intercellular Communication | Dysbiosis gut microbiota associated with inflammation and impaired mucosal immune function in intestine of humans with non-alcoholic fatty liver disease. | 25644696 |
| Inflammation, Non-alcoholic Fatty Liver Disease, Impaired health, Dysbiosis | Altered Intercellular Communication | We postulate that aside from dysbiosis of the gut microbiota, gut microbiota-mediated inflammation of the intestinal mucosa and the related impairment in mucosal immune function play an important role in the pathogenesis of NAFLD. | 25644696 |
| Airway structure, Hypoxia, Osage language | Altered Intercellular Communication | Increased alveolar NO concentration was related to the severity of nocturnal oxygen desaturation in patients with OSA, linking the distal airway inflammation to intermittent hypoxia. | 25645200 |
| Inflammation, Atherosclerosis | Altered Intercellular Communication | Purinergic signaling plays an important role in inflammation and vascular integrity, but little is known about purinergic mechanisms during the pathogenesis of atherosclerosis in humans. | 25645301 |
| Inflammation, Demographics Domain, Diabetes Mellitus, Non-Insulin-Dependent | Altered Intercellular Communication | Previous studies reported beneficial effects of cocoa or chocolate on insulin resistance, oxidative stress, and inflammation, which are important risk factors of type 2 diabetes mellitus (DM). | 25646334 |
| Granulomatous inflammation, Malignant Neoplasms | Altered Intercellular Communication | Differentiation between granulomatous inflammation and malignancy is challenging with 18F-FDG-PET/CT because of a large number of false-positive findings. | 25646704 |
| Gastrointestinal inflammation, Dysbiosis | Altered Intercellular Communication | Fecal microbial transplant (FMT) is a potential therapeutic option for individuals with CD based on the hypothesis that changing the fecal dysbiosis could promote less intestinal inflammation. | 25647155 |
| Inflammation, ovarian neoplasm | Altered Intercellular Communication | We prospectively examined the association between HPA activity, tumor-associated inflammation, and survival in ovarian cancer patients prior to treatment. | 25647344 |
| Inflammation, Congenital Abnormality | Altered Intercellular Communication | HPA abnormalities may reflect poor endogenous control of inflammation, dysregulation caused by tumor-associated inflammation, broad circadian disruption, or some combination of these factors. | 25647344 |
| Inflammation, Inflammatory disorder, HIV Infections | Altered Intercellular Communication | Chronic inflammation and immune activation occur in both HIV infection and normal aging and are associated with inflammatory disease. | 25647525 |
| Inflammation, Prostate carcinoma | Altered Intercellular Communication | Inflammation, and more generally, the immune response are thought to influence the development of prostate cancer. | 25648070 |
| Inflammation, Cardio-Renal Syndrome, Craniosynostosis, Atherosclerosis | Altered Intercellular Communication | To determine levels of interleukin-8 (IL-8) and plasminogen activator inhibitor-1 (PAI-1) in different cardiorenal syndrome (CRS) modalities and to compare findings to some already investigated direct and indirect parameters of inflammation and atherosclerosis. | 25648331 |
| hepcidin, Nephritis | Altered Intercellular Communication | Urinary monocyte chemoattractant protein-1 (MCP-1) and hepcidin are potential biomarkers of renal inflammation. | 25648911 |
| Inflammation, Hyperuricemia | Altered Intercellular Communication | Hyperuricaemia causes a shift in the IL-1b/IL-1Ra balance produced by PBMCs after exposure to MSU crystals and TLR-mediated stimuli, and this phenomenon is likely to reinforce the enhanced state of chronic inflammation. | 25649144 |
| Granulomatous inflammation, Malignant Neoplasms, Actinomycosis | Altered Intercellular Communication | Histological study showed a polymorphous granulomatous inflammation without signs of malignancy with actinomycotic grains. | 25649200 |
| Multimorbidity | Altered Intercellular Communication | Inflammation Partially Mediates the Association of Multimorbidity and Functional Limitations in a National Sample of Middle-Aged and Older Adults: The MIDUS Study. | 25649677 |
| Multimorbidity, Inflammation | Altered Intercellular Communication | Here we examine the role of inflammation in mediating the relationship between multimorbidity and disability. | 25649677 |
| Multimorbidity, Inflammation | Altered Intercellular Communication | After adjustment for potential confounds, multimorbidity was positively associated with inflammation (p < .001) and functional limitations (p < .001), and inflammation partially mediated the link between multimorbidity and functional limitations (p < .01). | 25649677 |
| Disability, Inflammation | Altered Intercellular Communication | Inflammation may be an important biological mechanism through which chronic medical conditions are linked to disability in later life. | 25649677 |
| Inflammation, Common Compensatory Fascial Pattern | Altered Intercellular Communication | The rheumatologist findings had 94.2% sensitivity and 84.6% specificity for inflammation; corresponding values were 80.7% and 100% for MSU microcrystals and 66.7% and 93.2% for CCP microcrystals. | 25649725 |
| Crohn Disease, Inflammation | Altered Intercellular Communication | Crohn's disease of the small bowel: evaluation of ileal inflammation by diffusion-weighted MR imaging and correlation with the Harvey-Bradshaw index. | 25650083 |
| Inflammation, Crohn Disease | Altered Intercellular Communication | This study was undertaken to determine the diagnostic capabilities of diffusion-weighted magnetic resonance imaging (DWI) in detecting ileal inflammation in Crohn's disease (CD), and to verify the correlation between the DWI sequences and the Harvey-Bradshaw index (HBI). | 25650083 |
| Inflammation, Uveitis | Altered Intercellular Communication | These algorithms were then applied to OCT images obtained from uveitis patients with active anterior chamber inflammation. | 25650415 |
| Gastric Cardia Carcinoma | Altered Intercellular Communication | Chronic inflammation-related DNA damage response: a driving force of gastric cardia carcinogenesis. | 25650663 |
| Aggressive course, Chronic inflammation, Gastric Cardia Carcinoma | Altered Intercellular Communication | Gastric cardia cancer (GCC) is a highly aggressive disease associated with chronic inflammation. | 25650663 |
| Inflammation, Cardia of stomach, Gastric Cardia Carcinoma | Altered Intercellular Communication | To investigate the relationship between DNA damage response (DDR) and chronic inflammation, we collected 100 non-tumor gastric cardia specimens of Chaoshan littoral, a high-risk region for esophageal and gastric cardia cancer. | 25650663 |
| Inflammation | Altered Intercellular Communication | A significantly higher proportion of severe chronic inflammation was found in dysplastic epithelia (80.9%) in comparison with that in non-dysplastic tissues (40.7%) (P<0.001). | 25650663 |
| Inflammation | Altered Intercellular Communication | Immunohistochemical analysis demonstrated that DNA damage response was parallel with the chronic inflammation degrees from normal to severe inflammation (P<0.05). | 25650663 |
| Gastric Cardia Carcinoma | Altered Intercellular Communication | These findings provide pathological evidence that persistent chronic inflammation-related DNA damage response may be a driving force of gastric cardia carcinogenesis. | 25650663 |
| Inflammation, De Quervain Disease | Altered Intercellular Communication | Inflammation is present in de Quervain Disease--correlation study between biochemical and histopathological evaluation. | 25650747 |
| Inflammation, Fibrosis Assessment | Altered Intercellular Communication | Previous studies consistently reported that the pathological change of this condition is thought to be primarily an extensor retinaculum thickened by fibrosis and angiogenesis instead of inflammation. | 25650747 |
| Glaucoma, Primary Open Angle, Failure, Infection, Conjunctivitis | Altered Intercellular Communication | Being a contributor to low-grade conjunctival inflammation, latent conjunctival CT, and BF infections in primary open-angle glaucoma patients represent risk factors for posttrabeculectomy bleb failure. | 25651208 |
| Communicable Diseases, Inflammation, Dermatomycoses | Altered Intercellular Communication | As TLR2 expression acts to limit the inflammatory process and preserves the epidermal structure, its preserved expression may also contribute to the persistent infection and limited inflammation that are characteristic of dermatophytic infections. | 25651327 |
| Inflammation, Prostate carcinoma | Altered Intercellular Communication | Prostate cancer has become a public health problem in many countries and there is evidence which indicates that inflammation and oxidative stress play a key role in the pathogenesis of this disease. | 25651717 |
| Inflammation, Diabetic Foot | Altered Intercellular Communication | Diabetic foot disease: grading inflammation by apolipoprotein A-I, C-reactive protein and serum amyloid A. | 25651728 |
| ARCN1 gene, Chronic Obstructive Airway Disease, Pneumonitis, Exacerbation | Altered Intercellular Communication | Chronic obstructive pulmonary disease (COPD) is characterised by chronic pulmonary inflammation punctuated by periods of viral exacerbations. | 25652132 |
| Autoimmune Diseases, Inflammation | Altered Intercellular Communication | Elevated concentrations of inflammatory mediators are characteristic of autoimmune disease accompanied by chronic or recurrent inflammation. | 25652333 |
| Inflammation, Lupus Erythematosus, Systemic, Refractory anemias, Rheumatoid Arthritis, Inflammatory disorder, Lupus Erythematosus | Altered Intercellular Communication | We examined the hypothesis that mediators of inflammation known to be elevated in systemic lupus erythematosus (SLE) and rheumatoid arthritis (RA) are associated with genetic polymorphism previously identified in studies of inflammatory disease. | 25652333 |
| Refractory anemias, Inflammation, Lupus Erythematosus, Systemic | Altered Intercellular Communication | Some genetic associations are more apparent in healthy controls than in SLE or RA, suggesting dysregulation of the principal mediators of chronic inflammation in disease. | 25652333 |
| Hyperglycemia, Bothered by Vomiting, Nausea, Inflammatory disease of mucous membrane, Fatigue | Altered Intercellular Communication | The most common treatment-related adverse events (AE) were mucosal inflammation/stomatitis (58.4%), nausea (42.9%), hyperglycemia (26%), decreased appetite (24.7%), fatigue (24.7%), and vomiting (24.7%). | 25652454 |
| ARCN1 gene, Inflammation | Altered Intercellular Communication | Loss of GD1-positive Lactobacillus correlates with inflammation in human lungs with COPD. | 25652802 |
| Pneumonitis | Altered Intercellular Communication | Primary outcome measure was GD1 positivity within each group and whether or not this impacted quantitative histological measures of lung inflammation. | 25652802 |
| ARCN1 gene, Inflammation | Altered Intercellular Communication | Secondary outcome measures included Lactobacillus presence and quantification, and quantitative histological measurements of inflammation and remodelling in early COPD. | 25652802 |
| Inflammation, Anxiety, CTCAE 3.0, Depression, CTCAE, Dyspnea, Fatigue | Altered Intercellular Communication | Fatigue, dyspnoea, depression and anxiety, symptom burden, body composition, physical capacity (lung function, exercise capacity, muscle strength), exacerbation rate and systemic inflammation were assessed. | 25653122 |
| Anxiety, CTCAE 3.0, Inflammation, Depression, CTCAE | Altered Intercellular Communication | No relationship was found between depression, anxiety, body composition, exacerbation rate or systemic inflammation and PA. | 25653122 |
| Low Back Pain, Inflammation, Intervertebral Disk Displacement | Altered Intercellular Communication | Earlier studies indicate that lumbar radicular pain after disc herniation may be associated with a local inflammation induced by leakage of nucleus pulposus (NP) into the spinal canal and neuroforamen. | 25653193 |
| Inflammation, Blood coagulation, Headache | Altered Intercellular Communication | Short-term increases in air pollution exposure may trigger headache by increasing pulmonary and systemic inflammation, increasing blood coagulability or altering endothelial function. | 25653308 |
| Airway structure | Altered Intercellular Communication | Airway inflammation and ammonia exposure among female Palestinian hairdressers: a cross-sectional study. | 25653315 |
| Airway structure | Altered Intercellular Communication | Little is known about the working conditions and airway inflammation in hairdressers in Palestine. | 25653315 |
| Airway structure | Altered Intercellular Communication | We aimed to investigate if hairdressers in Palestine have a higher level of airway inflammation as compared to a control group. | 25653315 |
| Airway structure | Altered Intercellular Communication | Compared to unexposed controls, the hairdressers had signs of neutrophilic airway inflammation, higher eNO levels and higher CRP. | 25653315 |
| Pneumoconiosis, Pneumonitis | Altered Intercellular Communication | Coal workers' pneumoconiosis (CWP) is characterized as a chronic inflammation of the lung associated with activation of macrophages and endothelial cells in the lung. | 25653483 |
| Inflammation, CEL gene, Ulcerative Colitis | Altered Intercellular Communication | In contrast, functional analyses of aberrantly expressed genes between UC and FAP samples, irrespective of mucosal inflammation status, revealed multiple pathways and terms that were linked to changes in immune response. | 25654358 |
| CEL gene, Ulcerative Colitis | Altered Intercellular Communication | Interestingly, the comparison of uninflamed UC and FAP samples identified a set of 29 altered probe sets, including an inflammation-related transcript encoding a Charcot-Leyden crystal (CLC) protein. | 25654358 |
| Inflammation, CEL gene, Ulcerative Colitis | Altered Intercellular Communication | Our study confirmed that alterations in immune responses can be found between patients who underwent surgery for UC and FAP, independent of the pouch inflammation status. | 25654358 |
| Inflammation, Acanthosis, Fibrosis Assessment, Hyperplasia | Altered Intercellular Communication | The wound was debrided and pathology showed epithelial hyperplasia, acanthosis, hyperkatosis accompanied by mild inflammation, and fibrosis without any malignant transformation. | 25654781 |
| Sinusitis | Altered Intercellular Communication | Nasal endoscopy showed only an intranasal mucosal contact point between the septal crest and the right inferior turbinate, without other signs of sinus inflammation. | 25655316 |
| Inflammation, Fever, CTCAE | Altered Intercellular Communication | Patients with increased inflammatory parameters, nonspecific signs and symptoms without fever and without a diagnosis after a variety of diagnostic procedures are a diagnostic dilemma and are referred to as having inflammation of unknown origin (IUO). | 25655485 |
| Inflammation, Immune System Diseases | Altered Intercellular Communication | Zinc deficiency results in immune dysfunction and promotes systemic inflammation. | 25656040 |
| Inflammation, Humoral immune defect | Altered Intercellular Communication | This work is potentially relevant to the aging population given that age-related immune defects, including chronic inflammation, coincide with declining zinc status. | 25656040 |
| Inflammation | Altered Intercellular Communication | Our results suggested potential interactions between zinc status, epigenetics, and immune function, and how their dysregulation could contribute to chronic inflammation. | 25656040 |
| Inflammation, Infection caused by Helicobacter pylori | Altered Intercellular Communication | In the patients with H. pylori infection there was a significant relationship between cagA positivity and neutrophil activity (P = 0.004) and chronic inflammation (P = 0.013) and with H. pylori density (P = 0.034). | 25656240 |
| Pancreatitis | Altered Intercellular Communication | Pancreatitis-an inflammation of pancreas-is a severe and costly disease. | 25656921 |
| Inflammation, Cellulitis | Altered Intercellular Communication | In this pilot study, we evaluated whether levels of YKL-40, an acute-phase reactant, and mean platelet volume (MPV), which occurs secondary to inflammation in cellulitis, increase compared to healthy subjects. | 25657159 |
| Inflammation, Ventricular Dysfunction | Altered Intercellular Communication | The presence of central abdominal fat and systemic inflammation seems implicated in the pathogenesis of vascular dysfunctions in MetS. | 25657309 |
| Inflammation, Heart Failure, Systolic | Altered Intercellular Communication | The heart has close interactions with other organs' functions and concomitant systemic factors such as oxidative stress, nitric oxide (NO), inflammation, and nutrition in systolic heart failure (HF). | 25658112 |
| Inflammation, Ulcerative Colitis | Altered Intercellular Communication | To identify biomarkers that correlate with pouch inflammation, ulcerative colitis pouch patients were prospectively recruited and underwent clinical, endoscopic, and histologic evaluations. | 25659085 |
| Pain Distress Question, Chronic pain | Altered Intercellular Communication | Relationship between blood- and cerebrospinal fluid-bound neurotransmitter concentrations and conditioned pain modulation in pain-free and chronic pain subjects. | 25659204 |
| Inflammation | Altered Intercellular Communication | We also found that CMV-seropositivity is associated with increased levels of B cell-intrinsic inflammation and these both correlate with lower B cell function. | 25659271 |
| Inflammation, Primary malignant neoplasm, Neoplastic Cell Transformation | Altered Intercellular Communication | Inflammation plays an important role in promoting ovarian tumorigenesis and cancer progression. | 25659662 |
| Sepsis, Inflammation, Damage | Altered Intercellular Communication | Excessive inflammation is a major cause of organ damage during sepsis. | 25659903 |
| Sepsis, Pneumonitis | Altered Intercellular Communication | In summary, our results suggest that Sirt1 suppresses acute lung inflammation during sepsis by controlling inflammasome activation pathway. | 25659903 |
| Inflammation, Abnormality of the hair shaft, Hypergranulosis, Hyperkeratosis | Altered Intercellular Communication | Major histologic and dermatoscopic findings of KP were hyperkeratosis, hypergranulosis, mild T helper cell type 1-dominant lymphocytic inflammation, plugging of follicular orifices, striking absence of sebaceous glands, and hair shaft abnormalities in KP lesions but not in unaffected skin sites. | 25660180 |
| Inflammation | Altered Intercellular Communication | L-92 may contribute to the suppression of Th2-dominant inflammation. | 25660281 |
| Tissue damage, Tumor necrosis, Chronic disease | Altered Intercellular Communication | Tumor necrosis factor (TNF), a potent inflammatory cytokine, and mitochondrial DNA (mtDNA), a product of inflammation-induced tissue damage, increase with age ("inflammaging") and many chronic diseases. | 25660689 |
| Tissue damage, Tumor necrosis, Chronic disease | Altered Intercellular Communication | Tumor necrosis factor (TNF), a potent inflammatory cytokine, and mitochondrial DNA (mtDNA), a product of inflammation-induced tissue damage, increase with age ("inflammaging") and many chronic diseases. | 25660689 |
| Inflammation, Inflammatory disorder, Gout | Altered Intercellular Communication | Gout is a polygenic auto-inflammatory disease, in which inflammation plays an important role in disease pathogenesis. | 25661540 |
| Inflammation, Immune System Diseases | Altered Intercellular Communication | The cytokine interleukin (IL)-23 promotes inflammation and helps to guide inflammatory cells, while studies have shown that the IL-23R gene is associated with susceptibility to several immune-related diseases. | 25661540 |
| Blood capillaries, Blood Clot, Vasculitis, CTCAE | Altered Intercellular Communication | The kidney biopsy revealed diffuse endocapillary proliferation and leukocyte exudation with focal intraluminal hyaline thrombi, prominent tubulointerstitial inflammation, and vasculitis. | 25661680 |
| methyldopa, Inflammation | Altered Intercellular Communication | In the pathogenesis of AMD, degeneration of RPE cells by multiple factors including increased oxidative stress and chronic inflammation precedes the irreversible loss of photoreceptors and central vision. | 25662315 |
| Inflammation | Altered Intercellular Communication | Here, we report that the plant-derived polyphenol, quercetin, increases viability and decreases inflammation in stressed human ARPE-19 cells after exposure to the lipid peroxidation end product 4-hydroxynonenal (HNE). | 25662315 |
| Parkinson Disease, Inflammation, REM Sleep Behavior Disorder | Altered Intercellular Communication | Parkinson disease with REM sleep behavior disorder: features, a-synuclein, and inflammation. | 25663225 |
| Parkinson Disease, Inflammation, palladium, REM Sleep Behavior Disorder | Altered Intercellular Communication | To investigate clinical features and potential mechanisms involving a-synuclein oligomer and inflammation in patients with Parkinson disease (PD) and probable REM sleep behavior disorder (PRBD). | 25663225 |
| Communicable Diseases, Inflammation | Altered Intercellular Communication | Autophagy, a degradation pathway in which cytoplasmic content is engulfed and degraded by lysosomal hydrolases, plays a pivotal role in infection and inflammation. | 25664588 |
| Gastrointestinal inflammation | Altered Intercellular Communication | Heme oxygenase-1 confers protection and alters T-cell populations in a mouse model of neonatal intestinal inflammation. | 25665053 |
| Vasculitis | Altered Intercellular Communication | Whole-body CE-MRI with vessel wall imaging detected luminal changes and vessel wall inflammation in TA. | 25665823 |
| Alzheimers Disease", Inflammation, Data types - Address | Altered Intercellular Communication | The brains of Alzheimer's disease (AD) patients are characterized by deposits of Abeta peptides and by accompanying chronic inflammation. | 25666182 |
| Colitis | Altered Intercellular Communication | Prostaglandin E2 (PGE2) is the dominant prostaglandin in the colon and is associated with colonic inflammation. | 25666316 |
| Colitis | Altered Intercellular Communication | Information about the involvement of 15-PGDH in colonic inflammation is sparse. | 25666316 |
| Inflammation | Altered Intercellular Communication | With respect to DD, alterations of PGE2-related enzymes suggest that a low PGE2 level may precede the onset of inflammation, thus providing new insight into the pathogenesis of DD. | 25666316 |
| Pain Distress Question, Inflammation | Altered Intercellular Communication | The sodium chloride formulation was further tested in rabbits and did not show acute clinical signs of pain or inflammation. | 25666331 |
| Inflammation, Dysautonomia, Familial | Altered Intercellular Communication | In addition, biological pathways mainly affected by FD are related to immune response, inflammation, and energetic metabolism. | 25666440 |
| Inflammation, Dysautonomia, Familial, Kidney damage | Altered Intercellular Communication | In particular, the up-regulation of uromodulin, prostaglandin H2 d-isomerase and prosaposin in the urine of FD patients was demonstrated; these proteins might be involved in kidney damage at the tubular level, inflammation and immune response. | 25666440 |
| Inflammation | Altered Intercellular Communication | Recent studies have suggested that inflammation is a major contributor to WNV encephalitis morbidity. | 25667322 |
| Inflammation, Coronary Artery Disease, Atherosclerosis | Altered Intercellular Communication | Inflammation plays a key role in coronary artery disease (CAD) and other manifestations of atherosclerosis. | 25668619 |
| Inflammation | Altered Intercellular Communication | Recently, urinary proteins were found to be useful markers for reflecting inflammation status of different organs. | 25668619 |
| Gastrointestinal Hemorrhage, Inflammation, Malignant Neoplasms, Neoplasms | Altered Intercellular Communication | To compare Tf and Hb as markers of gastrointestinal hemorrhage, we conducted a quantitative enzyme-linked immunosorbent assay (ELISA) for both proteins in 53 cases, with subsequent analysis based on lesion groups (malignant tumor, benign tumor, or inflammation). | 25669034 |
| Autoimmune Diseases, Communicable Diseases, Malignant Neoplasms | Altered Intercellular Communication | The erythrocyte sedimentation rate (ESR) has been used as an index for inflammatory conditions, such as infectious diseases, autoimmune diseases, and malignancies. | 25669035 |
| Communicable Diseases, Granulomatous, Pneumonitis | Altered Intercellular Communication | However, increased 18 F-FDG uptake was also seen in benign lesions such as active pulmonary inflammation or infection, granulomatous processes and fibrotic lesions. | 25669335 |
| Inflammation, Native Valve Endocarditis | Altered Intercellular Communication | Performing a reoperative root replacement in cases of prosthetic valve endocarditis (PVE) can often be challenging due to significant inflammation and scarring. | 25669643 |
| Inflammation, Autistic Disorder | Altered Intercellular Communication | The etiology of autism is poorly understood, the evidence indicates that inflammation may play a key role. | 25669692 |
| Inflammation, Autistic Disorder, Abnormal digestive tract function | Altered Intercellular Communication | In autism a high prevalence of gastrointestinal disturbances is reported, that are linked to a low-grade chronic inflammation of the intestinal mucosa. | 25669692 |
| Inflammation, Autistic Disorder | Altered Intercellular Communication | Results of the study support the involvement of the systemic low-grade inflammation in the pathomechanisms of autism and its possible association with GI symptoms. | 25669692 |
| Liver carcinoma, FAM126A gene | Altered Intercellular Communication | Several papers have shown that preoperative inflammation-based prognostic scores and/or immunonutritional status are associated with survival in patients with hepatocellular carcinoma (HCC). | 25670038 |
| Inflammation, diabetic | Altered Intercellular Communication | Data reported in the present study, together with the results of previous studies, further support a relationship between glycemic control and periapical inflammation in diabetic patients. | 25670246 |
| Inflammation, Cardiac function | Altered Intercellular Communication | Characteristics regarding general condition, inflammation, and cardiac and renal function were the decisive factors of NT-proBNP (P<0.05 for all). | 25670892 |
| Airway structure, ARCN1 gene | Altered Intercellular Communication | Airway inflammation in Japanese COPD patients compared with smoking and nonsmoking controls. | 25670894 |
| ARCN1 gene, Inflammation, Chronic Obstructive Airway Disease | Altered Intercellular Communication | To assess the importance of inflammation in chronic obstructive pulmonary disease (COPD) by measuring airway and systemic inflammatory biomarkers in Japanese patients with the disease and relevant control groups. | 25670894 |
| ARCN1 gene, Inflammation, Airway Obstruction | Altered Intercellular Communication | These results provide evidence for the first time that COPD in Japanese patients is a multicomponent disease, involving both airway and systemic inflammation, in addition to airway obstruction. | 25670894 |
| Inflammation, Panniculitis, Systemic disease | Altered Intercellular Communication | Panniculitis is an inflammation of the subcutaneous adipose tissue and can be associated with systemic diseases. | 25671441 |
| Inflammation, Neoplasms | Altered Intercellular Communication | Galectins affect diverse physiological and pathophysiological processes such as development, inflammation, and tumor growth. | 25672239 |
| Sepsis, Inflammation | Altered Intercellular Communication | Although there seems to be some connection between vaspin and inflammation, its role in human sepsis needs to be evaluated further. | 25672472 |
| Inflammation, Tuberculosis | Altered Intercellular Communication | Interventions that decrease inflammation while promoting cellular immune recovery during ART should be considered in patients co-infected with HIV and tuberculosis. | 25672566 |
| Airway structure, Aortic Stiffness | Altered Intercellular Communication | Aortic stiffness, an independent predictor of cardiovascular risk, and systemic and airway inflammation are increased in patients with the disease. | 25673981 |
| Airway structure, Chronic Obstructive Airway Disease, Aortic Stiffness | Altered Intercellular Communication | A proof-of-principle, double-blind, randomized trial determined if 6 weeks of simvastatin 20 mg once daily reduced aortic stiffness and systemic and airway inflammation in patients with chronic obstructive pulmonary disease. | 25673981 |
| ARCN1 gene, Inflammation, Osteoporosis, Osage language, Sleep Apnea, Obstructive | Altered Intercellular Communication | Worse systemic inflammation and reduced exercise capacity have been reported in COPD patients with obstructive sleep apnea (OSA), implying that OSA may be an independent factor for osteoporosis in COPD patients. | 25673983 |
| Deglutition Disorders, Neck muscle weakness, Dysarthria, CTCAE, Mitochondrial Myopathies | Altered Intercellular Communication | After treated with prednisone, the symptoms of dysphagia, dysarthria and neck muscle weakness were significantly improved, and the second biopsy showed only mitochondrial myopathy pathology but the inflammations disappeared. | 25674260 |
| Inflammatory Bowel Diseases | Altered Intercellular Communication | Inflammatory bowel disease (IBD) is an inflammatory condition of the digestive tract not caused by infectious agents. | 25674731 |
| Cessation of life, Pathology | Altered Intercellular Communication | The implication of the neuromodulator serotonin also in the aetiology of sudden unexplained fetal and infant death syndromes and the demonstration in these pathologies of developmental alterations of the superior olivary complex (SOC), a group of pontine nuclei likewise involved in hearing, prompted us to investigate whether the inferior colliculus may somehow contribute to the pathogenetic mechanism of unexplained perinatal death. | 25674737 |
| vascular inflammations, Iliac Aneurysm | Altered Intercellular Communication | Vascular inflammation in a growing iliac artery aneurysm. | 25674872 |
| Inflammation | Altered Intercellular Communication | The combined PET and MRI evaluation of inflammation that we present here is a novel approach to vascular imaging that is well suited for emerging hybrid PET/MRI systems. | 25674872 |
| Inflammation, Anemia, Comorbidity | Altered Intercellular Communication | Most anaemias are due to a deficiency, chronic inflammation or comorbidity. | 25675644 |
| Tumor necrosis, Inflammation | Altered Intercellular Communication | Tumor necrosis factor-like weak inducer of apoptosis (TWEAK) and tumor necrosis factor superfamily member 15 (TNFSF15), members of the TNF superfamily, play important roles in the modulation of inflammation and neovascularization. | 25676319 |
| Inflammation, PDR gene | Altered Intercellular Communication | Our findings suggest that TNFSF15 and the TWEAK/Fn14 pathway are novel mediators involved in persistent inflammation and modulation of pathological neovascularization associated with PDR. | 25676319 |
| Inflammation | Altered Intercellular Communication | Adiposity Alters Genes Important in Inflammation and Cell Cycle Division in Human Cumulus Granulosa Cell. | 25676576 |
| Inflammation, Obesity | Altered Intercellular Communication | To determine whether obesity alters genes important in cellular growth and inflammation in human cumulus granulosa cells (GCs). | 25676576 |
| Inflammation, Obesity | Altered Intercellular Communication | Adiposity is associated with changes in the expression of genes important in cellular growth, cell cycle progression, and inflammation. | 25676576 |
| Inflammation | Altered Intercellular Communication | The mechanisms leading to systemic inflammation after chloroform intoxication are currently unclear. | 25676899 |
| Inflammation, Scotoma, Central, Retinitis Pigmentosa | Altered Intercellular Communication | These results suggest a close relationship between inflammation and central vision loss in RP. | 25677184 |
| Cataract, Intraocular inflammation | Altered Intercellular Communication | Monitoring of best-corrected visual acuity, intraocular inflammation, cataract progression, and retinal structure by spectral domain optical coherence tomography was done at 1 day and 1 week after injection. | 25677668 |
| methyldopa, Intraocular inflammation, retinal toxicity | Altered Intercellular Communication | There were no signs of retinal toxicity, intraocular inflammation or change in lens status in four eyes with AMD and two eyes with DME. | 25677668 |
| Inflammation, Metabolic Syndrome X, Obesity | Altered Intercellular Communication | On the other hand, lower SALs are due to obesity, inflammation and presence of already 2 components of metabolic syndrome. | 25677829 |
| Inflammation, Neoplasms | Altered Intercellular Communication | * Focal marginal uptake can be due to recurrent tumour or inflammation. | 25678079 |
| Inflammation | Altered Intercellular Communication | Evidence suggests that the COX-2 pathway, an important component of inflammation, may be involved in the disease. | 25679523 |
| Neurodegenerative Disorders, "Alzheimers Disease", Data types - Address | Altered Intercellular Communication | Alzheimer's disease (AD) is a neurodegenerative disorder involving impaired cholinergic neurotransmission and dysregulation of nicotinic acetylcholine receptors (nAChRs). | 25680266 |
| Malnutrition | Altered Intercellular Communication | Malnutrition was evaluated through subjective global assessment (SGA) and malnutrition inflammation score (MIS). | 25680525 |
| Inflammation, Malignant Neoplasms, Squamous cell carcinoma of the head and neck | Altered Intercellular Communication | Change of maximum standardized uptake value slope in dynamic triphasic [18F]-fluorodeoxyglucose positron emission tomography/computed tomography distinguishes malignancy from postradiation inflammation in head-and-neck squamous cell carcinoma: a prospective trial. | 25680593 |
| Cholecystitis, Fibrosis Assessment, Phlebitis | Altered Intercellular Communication | Immunoglobulin (Ig)G4-associated cholecystitis is also a newly described cholecystitis variant characterized by transmural or extramural lymphoplasmacytic inflammation, lymphoid follicles, storiform fibrosis, phlebitis, and increased tissue IgG4-positive plasma cells. | 25680903 |
| Inflammation | Altered Intercellular Communication | Hypo-osmotic shock-induced subclinical inflammation of skin in a rat model of disrupted skin barrier function. | 25681269 |
| Shock, Dermatitis | Altered Intercellular Communication | We conducted the present study to test the hypothesis that hypo-osmotic shock of epidermal cells induces skin inflammation and elongation of C-fibers by nerve growth factor b (NGFb) as a basic mechanism of APE. | 25681269 |
| ARCN1 gene, Chronic Obstructive Airway Disease, Inflammatory disease of mucous membrane | Altered Intercellular Communication | Chronic obstructive pulmonary disease (COPD) is characterized by neutrophil-dominated airway mucosal inflammation and elevated neutrophil counts in sputum and lung tissue. | 25681277 |
| Inflammation, Fatty degeneration | Altered Intercellular Communication | Nonspecific abnormalities alone were seen in 22 (35%) subjects, including mild steatosis, mild to moderate inflammation, and evidence of drug adaptation. | 25681381 |
| Interstitial inflammation | Altered Intercellular Communication | Histologic plugs were similar in UA and CaOx SF, although CaOx SF demonstrated greater interstitial inflammation on endoscopic biopsy. | 25681832 |
| Inflammation, Atherosclerosis | Altered Intercellular Communication | Autoimmune responses against oxidized-LDL (oxLDL) have been suggested to modulate inflammation in atherosclerosis. | 25682025 |
| Inflammation, Peripheral Arterial Diseases, Coronary Artery Disease | Altered Intercellular Communication | Systemic inflammation is higher in peripheral artery disease than in stable coronary artery disease. | 25682027 |
| Inflammation, Peripheral Arterial Diseases, Coronary Artery Disease | Altered Intercellular Communication | The knowledge on the level of systemic inflammation in peripheral artery disease (PAD) is less well established than that in coronary artery disease (CAD). | 25682027 |
| Inflammation, Metabolic Syndrome X, ETV3 wt Allele, Atherosclerosis | Altered Intercellular Communication | Systemic inflammation frequently coincides with atherosclerosis, but also with various traits of the metabolic syndrome (MetS). | 25682027 |
| Inflammation, ETV3 wt Allele | Altered Intercellular Communication | The individual contribution of CAD, PAD, and the MetS to inflammation is not known. | 25682027 |
| Inflammation, ETV3 wt Allele | Altered Intercellular Communication | Low grade systemic inflammation is independently associated with both the MetS and PAD. | 25682027 |
| Inflammation, Cardiovascular Diseases, Atherosclerosis | Altered Intercellular Communication | Relationship of pericardial fat with biomarkers of inflammation and hemostasis, and cardiovascular disease: the Multi-Ethnic Study of Atherosclerosis. | 25682037 |
| Inflammation, Cyclophosphamide/Vincristine/Dacarbazine Regimen, Cardiovascular Diseases | Altered Intercellular Communication | Pericardial fat may increase the risk of cardiovascular disease (CVD) by increasing circulating levels of inflammation and hemostasis biomarkers. | 25682037 |
| Inflammation, Obesity, Abdominal, Periodontal Diseases | Altered Intercellular Communication | Abdominal obesity and periodontal diseases are believed to share close relation through commonality of chronic inflammation. | 25682300 |
| Inflammation, Breast Carcinoma | Altered Intercellular Communication | To investigate the possible role of deleted in breast cancer 1 (DBC1) in adipocyte and adipose tissue inflammation. | 25682741 |
| Inflammation, Metabolic Syndrome X, Atherosclerosis, Non-alcoholic Fatty Liver Disease, Obesity | Altered Intercellular Communication | The association of nonalcoholic fatty liver disease, obesity, and metabolic syndrome, with systemic inflammation and subclinical atherosclerosis: the Multi-Ethnic Study of Atherosclerosis (MESA). | 25683387 |
| Inflammation, Metabolic Syndrome X, Atherosclerosis, Non-alcoholic Fatty Liver Disease, Obesity | Altered Intercellular Communication | We characterized the association of 3 metabolic conditions - obesity, metabolic syndrome, and nonalcoholic fatty liver disease (NAFLD) - with increased inflammation and subclinical atherosclerosis. | 25683387 |
| Inflammation, SLC25A20 gene, Atherosclerosis | Altered Intercellular Communication | Increased inflammation was defined as high sensitivity C-reactive protein (hsCRP) >=2 mg/L and subclinical atherosclerosis as coronary artery calcium (CAC) > 0. | 25683387 |
| Inflammation, SLC25A20 gene | Altered Intercellular Communication | We studied the association of a stepwise increase in number of these metabolic conditions (0-3) with increased inflammation and CAC, stratifying results by gender and ethnicity. | 25683387 |
| Inflammation, SLC25A20 gene, Metabolic Syndrome X, Non-alcoholic Fatty Liver Disease, Obesity | Altered Intercellular Communication | NAFLD is associated with increased inflammation and CAC independent of traditional risk factors, obesity and metabolic syndrome. | 25683387 |
| Inflammation, SLC25A20 gene, Metabolic Syndrome X, Non-alcoholic Fatty Liver Disease, Obesity | Altered Intercellular Communication | There is a graded association between obesity, metabolic syndrome, and NAFLD with inflammation and CAC. | 25683387 |
| Inflammation, Depression, CTCAE, Coronary heart disease | Altered Intercellular Communication | Insufficient glucocorticoid signaling and elevated inflammation in coronary heart disease patients with comorbid depression. | 25683698 |
| Inflammation, Depression, CTCAE, Choline Dehydrogenase, Mitochondrial | Altered Intercellular Communication | In conclusion, CHD patients with depression had elevated levels of inflammation in the context of HPA axis hypoactivity, GR resistance, and increased activation of the kynurenine pathway. | 25683698 |
| Neoplasms, Colitis | Altered Intercellular Communication | Immunohistochemical expression of SP-NK-1R-EGFR pathway and VDR in colonic inflammation and neoplasia. | 25684939 |
| Weight Gain, Inflammation | Altered Intercellular Communication | Relationship between relative interdialytic weight gain and serum leptin levels, nutrition, and inflammation in chronic hemodialysis patients. | 25685870 |
| HD Term Type, Inflammation | Altered Intercellular Communication | We aimed to assess the relationship between RIDWG and appetite, nutrition, inflammation parameters of chronic HD patients. | 25685870 |
| Inflammation, Dental Plaque, Dental caries, Osage language | Altered Intercellular Communication | OSA subjects had less dental caries, plaque deposition, and gingival inflammation and better oral hygiene. | 25685971 |
| Inflammatory abnormality of the eye | Altered Intercellular Communication | Ocular hypotony in PHA was thought to be due to intra-ocular inflammation. | 25686066 |
| Unknown (origin) (qualifier value), Inflammation, Cerebellar Ataxia | Altered Intercellular Communication | Acute or subacute cerebellar inflammation is mainly caused by postinfectious, toxic, neoplastic, vascular, or idiopathic processes and can result in cerebellar ataxia. | 25686577 |
| Inflammation, Virus Diseases, Cardiovascular Diseases | Altered Intercellular Communication | Increased risk of cardiovascular disease in patients infected with HIV has been attributed to immune activation, inflammation, and immunosenescence, all of which are linked to chronic immune activation by viral infections, particularly cytomegalovirus (CMV). | 25686677 |
| Inflammation, Intestines, Small | Altered Intercellular Communication | Xanthogranulomatous inflammation of terminal ileum: report of a case with small bowel involvement. | 25686705 |
| Inflammation | Altered Intercellular Communication | Xanthogranulomatous inflammation is a rare pathological condition most frequently detected in the kidney and gallbladder. | 25686705 |
| Xanthogranulomatous inflammation | Altered Intercellular Communication | Reported herein is a case of xanthogranulomatous inflammation in a 51-year-old male presenting as a mass-forming lesion in the terminal ileum with mucosal ulceration. | 25686705 |
| Xanthogranulomatous inflammation, gastrointestinal | Altered Intercellular Communication | This is a report of the condition involving the terminal ileum with mucosal ulceration and full-thickness involvement of bowel wall which are uncommon features of xanthogranulomatous inflammation in previously reported lower gastro-intestinal tract lesions. | 25686705 |
| Sarcoidosis, Inflammatory abnormality of the eye | Altered Intercellular Communication | Sarcoidosis in the national veteran population: association of ocular inflammation and mortality. | 25687027 |
| Sarcoidosis, Inflammatory abnormality of the eye, Orbital Pseudotumor, Uveitis | Altered Intercellular Communication | The sarcoidosis patients were divided into those with uveitis or orbital inflammation (defined as ocular inflammation for this study) and those without uveitis or orbital inflammation. | 25687027 |
| Inflammatory abnormality of the eye | Altered Intercellular Communication | Association between ocular inflammation and 1-year mortality. | 25687027 |
| Anterior uveitis, Inflammatory abnormality of the eye, Orbital granuloma | Altered Intercellular Communication | Most patients were diagnosed with anterior uveitis (n = 1013; 80.7% of ocular inflammation), and the least common diagnosis was orbital granuloma (n = 28; 2.2% of ocular inflammation). | 25687027 |
| Inflammatory abnormality of the eye | Altered Intercellular Communication | Ocular inflammation was associated with a decrease in 1-year all-cause mortality (simple model: hazard ratio, 0.36; P = 0.0015; complex model: hazard ratio, 0.35; P = 0.013). | 25687027 |
| Inflammatory abnormality of the eye | Altered Intercellular Communication | Veterans with ocular inflammation had significantly lower 1-year all-cause mortality than those without documented ocular inflammation. | 25687027 |
| Airway structure, Asthma | Altered Intercellular Communication | Our objective was to determine what impact the level of air pollutants had on the control of their asthma and the degree of airway inflammation. | 25687770 |
| Airway structure, Asthma | Altered Intercellular Communication | Disease control was assessed using asthma control test (ACT) scores, and airway inflammation using fraction of exhaled nitric oxide (FeNO) values. | 25687770 |
| Airway structure | Altered Intercellular Communication | We found no relationship between pollutants and airway inflammation. | 25687770 |
| Inflammation, Disorder of the optic nerve | Altered Intercellular Communication | A retrospective chart review was conducted on patients with glaucomatous optic neuropathy, chronic anterior or posterior segment inflammation, and >=6 months postoperative follow-up. | 25688057 |
| Inflammation | Altered Intercellular Communication | Inflammation plays an important role in the pathophysiology of CI-AKI. | 25688117 |
| Inflammation, Malnutrition, Atherosclerosis, HD Term Type, Non-alcoholic Fatty Liver Disease | Altered Intercellular Communication | NAFLD may be the missing link that causally ties malnutrition, inflammation, and atherosclerosis syndrome to the morbidity and mortality in patients undergoing HD. | 25688578 |
| Inflammatory disease of mucous membrane | Altered Intercellular Communication | CCR6 is a chemokine receptor involved in homing memory T cells, particularly Th17 cells, to sites of mucosal inflammation. | 25690781 |
| Inflammation, Hydronephrosis | Altered Intercellular Communication | We hypothesize that the obstruction and absence of hydronephrosis were caused by extrinsic compression and subsequent inflammation due to the fibrin glue. | 25694019 |
| Giant Cell Arteritis, vascular inflammations, Atherosclerosis | Altered Intercellular Communication | Both atherosclerosis and giant cell arteritis cause vascular inflammation, but distinguishing the two may be difficult. | 25695092 |
| Airway structure, ARCN1 gene, Chronic Obstructive Airway Disease | Altered Intercellular Communication | An antagonist (MK-7123) of the cytokine receptor CXCR2 reduces neutrophil chemotaxis and thus may alleviate airway inflammation in chronic obstructive pulmonary disease (COPD). | 25695403 |
| Inflammation, Malignant neoplasm of endometrium, Endometriosis | Altered Intercellular Communication | Nonetheless, endometriosis may also be associated with endometrial cancer because of shared etiological mechanisms of both estrogen stimulation and chronic inflammation; however, the association between these 2 disorders has rarely been investigated. | 25695548 |
| Inflammation, Metabolic Diseases, Obesity, Cardiovascular Diseases | Altered Intercellular Communication | Body fat distribution and inflammation may play a role in metabolic derangements and cardiovascular disease in obesity. | 25695885 |
| Hypertensive disease, Inflammation | Altered Intercellular Communication | [Serum markers of inflammation and lipid-releasing ability of leukocytes in patients with arterial hypertension and angina of effort]. | 25696963 |
| Inflammation, Hypertension, CTCAE, Coronary heart disease, Choline Dehydrogenase, Mitochondrial | Altered Intercellular Communication | The aim of the present work was to investigate serum markers of inflammation and LRAL in arterial hypertension (AH) without coronary heart disease (CHD) or AH + angina of effort. | 25696963 |
| Inflammation, Plaque, Atherosclerotic | Altered Intercellular Communication | Inflammation and angiogenesis play an important role in atherosclerotic plaque rupture. | 25698472 |
| Edema | Altered Intercellular Communication | Macular edema (ME) resulted to be associated to chronic postoperative inflammation (r = 0.6; p = 0.00) and mostly related to patients who presented more than one postoperative relapse/year (r = 0.2; p = 0.02). | 25700154 |
| Inflammatory abnormality of the eye | Altered Intercellular Communication | There was no case in which ocular inflammation was exacerbated by surgical stress. | 25700328 |
| Ocular sarcoidosis, Inflammatory abnormality of the eye | Altered Intercellular Communication | Improvement of visual acuity and resolution of ocular inflammation could be achieved by MIVS using wide-viewing system for complications of ocular sarcoidosis. | 25700328 |
| Inflammation, Depression, CTCAE | Altered Intercellular Communication | Inflammation is increasingly implicated as a mediating factor relating stress to physical disease and is strongly linked to depression. | 25700535 |
| Inflammation | Altered Intercellular Communication | Inflammation may, therefore, be implicated in processes associated with excess mortality and morbidity during unemployment. | 25700535 |
| Inflammation, "Alzheimers Disease | Altered Intercellular Communication | There is no correlation between peripheral inflammation and cognitive status at diagnosis in Alzheimer's disease. | 25700558 |
| Inflammation | Altered Intercellular Communication | C-reactive protein >10 mg/L and any acute or chronic inflammation were considered as exclusion criteria. | 25700558 |
| Generalized osteoarthritis, Inflammation, Degenerative polyarthritis, Metabolic Syndrome X | Altered Intercellular Communication | Generalized, polyarticular osteoarthritis and local, monoarticular osteoarthritis appear to be two different profiles; the former is a feature of osteoarthritis co-morbid with inflammation or the metabolic syndrome, while the latter is more typical of post-trauma osteoarthritis, especially in cases with severe malalignment. | 25701074 |
| Inflammation, Pseudoepitheliomatous hyperplasia | Altered Intercellular Communication | Histological examination showed pseudoepitheliomatous hyperplasia and severe submucosal inflammation with ovoid budding yeasts by Grocott's stain. | 25701260 |
| Coronary Artery Disease | Altered Intercellular Communication | Inflammation mediators have been recognized as risk factors for the pathogenesis of coronary artery disease (CAD). | 25701337 |
| Inflammation, Endothelial dysfunction, metabolic disturbance | Altered Intercellular Communication | At elevated concentrations, circulating leptin has been associated with metabolic disturbances, namely insulin resistance, elevated blood pressure, inflammation, and endothelial dysfunction. | 25701340 |
| Inflammation, Necrosis | Altered Intercellular Communication | Stage I was defined by focal inflammation without necrosis (n = 2); stage II by focal clusters of micro-abscesses appearing to coalesce (n = 41); and stage III by a single cavity with or without capsule (n = 64). | 25701525 |
| Inflammation | Altered Intercellular Communication | Histology of the biopsies from this site revealed chronic inflammation and reactive changes. | 25701830 |
| Inflammation, Intestine Resection, Malignant Neoplasms | Altered Intercellular Communication | Postoperatively, histology of resected bowel revealed chronic inflammation and no evidence of malignancy. | 25701830 |
| Hypernatremia, Inflammation, CORO1A gene, Transfusion Reaction, Transfusion-Related Acute Lung Injury | Altered Intercellular Communication | We hypothesized that biologic markers of inflammation could be used in conjunction with clinical predictors to distinguish transfusion-related acute lung injury (TRALI), transfusion-associated circulatory overload (TACO), and possible TRALI. | 25702590 |
| Inflammation, CORO1A gene, Transfusion-Related Acute Lung Injury | Altered Intercellular Communication | Before transfusion, there is evidence of systemic inflammation in patients who develop TRALI and possible TRALI but not TACO. | 25702590 |
| Inflammation, Diabetes Mellitus, Non-Insulin-Dependent | Altered Intercellular Communication | Glycemic control, inflammation, and cognitive function in older patients with type 2 diabetes. | 25703191 |
| Inflammation, Musculoskeletal torsion, function | Altered Intercellular Communication | We postulate that the constriction caused by inflammation is the precursor of torsion and that development of nerve torsion is facilitated by the rotational movements of limbs. | 25703205 |
| Inflammation, Fibrosis Assessment | Altered Intercellular Communication | The posterior falx and tentorium showing a hypointense center ("fibrosis") and enhancing periphery ("active inflammation") together mimicking "Eiffel-by-night" sign was found to be more commonly associated with IHP (60% vs 12.5%, p=0.03). | 25703277 |
| Increased insulin level, Inflammation, Neoplasms, Obesity | Altered Intercellular Communication | Obesity is associated with increased bioavailability of estrogen, hyperinsulinemia, and chronic inflammation, all of which may promote tumor growth. | 25703993 |
| Inflammation, Muscular Dystrophy, Facioscapulohumeral | Altered Intercellular Communication | We found no difference in the frequency of inflammation between FSHD types 1 and 2. | 25704033 |
| Inflammation, PLAU protein, human, Lung Injury | Altered Intercellular Communication | Urokinase-type plasminogen activator (uPA) augments inflammation and tissue remodeling during lung injury and repair. | 25706093 |
| Inflammation, Electrocardiogram: myocardial infarction (finding), Atherosclerosis | Altered Intercellular Communication | SIRT1 exerts protective effects against endothelial cells dysfunction, inflammation and atherosclerosis, indicating an important role on myocardial infarction (MI) pathogenesis. | 25706717 |
| Inflammation, Primary malignant neoplasm | Altered Intercellular Communication | Serum albumin is a widely acceptable method of assessing nutritional and inflammation status in cancer patients. | 25706773 |
| Inflammation, Infection | Altered Intercellular Communication | Immunity-related GTPase family M (IRGM) is a human protein highlighted for its contribution to autophagy upon inflammation and infections. | 25707354 |
| Inflammation, Fracture | Altered Intercellular Communication | We hypothesized that intraarticular fracture would alter the synovial environment and lead to increased local and systemic inflammation. | 25707992 |
| Inflammation, Intra-Articular Fractures, Synovitis | Altered Intercellular Communication | Articular fracture of the ankle increased acute local inflammation, as indicated by increased synovitis, increased macrophage infiltration into synovial tissue, and increased SF concentrations of biomarkers of inflammation. | 25707992 |
| vascular inflammations | Altered Intercellular Communication | Vaspin is an adipokine implicated in vascular inflammation and remodeling. | 25708680 |
| Inflammation, Chronic Obstructive Airway Disease, heart overload | Altered Intercellular Communication | Even in patients with stable chronic obstructive pulmonary disease, the serum troponin T concentration was controlled by at least three major factors, ie, systemic inflammation, advancing age, and right cardiac overload. | 25709425 |
| Bacterial Infections | Altered Intercellular Communication | Soluble urokinase-type plasminogen activator receptor (suPAR) levels increase in acute viral and bacterial infections and in diseases involving chronic inflammation. | 25709430 |
| ARCN1 gene, Chronic Obstructive Airway Disease, exacerbation acute | Altered Intercellular Communication | Chronic obstructive pulmonary disease (COPD) is a chronic inflammatory condition, and progresses with acute exacerbations. | 25709430 |
| Inflammation, Herpes | Altered Intercellular Communication | HCMV, like all other herpes viruses, has the ability to remain latent within the body of the host and can contribute in chronic inflammation. | 25710012 |
| Presenile dementia, Inflammation | Altered Intercellular Communication | Cerebral Amyloid Angiopathy-related Inflammation Presenting With Rapidly Progressive Dementia, Responsive to IVIg. | 25710131 |
| Inflammation, Observation Method - Coagulation, Atherosclerosis | Altered Intercellular Communication | Long-term exposure to air pollution and markers of inflammation, coagulation, and endothelial activation: a repeat-measures analysis in the Multi-Ethnic Study of Atherosclerosis (MESA). | 25710246 |
| Inflammation, Cardiovascular Diseases | Altered Intercellular Communication | Air pollution is associated with cardiovascular disease, and systemic inflammation may mediate this effect. | 25710246 |
| Inflammation, Observation Method - Coagulation | Altered Intercellular Communication | We assessed associations between long- and short-term concentrations of air pollution and markers of inflammation, coagulation, and endothelial activation. | 25710246 |
| vascular inflammations | Altered Intercellular Communication | Diverging trajectory patterns of systemic versus vascular inflammation over age in healthy Caucasians and African-Americans. | 25710295 |
| Inflammation, Cardiovascular Diseases | Altered Intercellular Communication | Age and inflammation are risk factors for cardiovascular disease but the impact of inflammation on cardiovascular risk across the lifespan is not understood. | 25710295 |
| Inflammation, vascular inflammations | Altered Intercellular Communication | The composite z-score for systemic inflammation increased with age, while the composite z-score for vascular inflammation declined with age, irrespective of ethnicity. | 25710295 |
| Alzheimers Disease", Data types - Address | Altered Intercellular Communication | Interleukin (IL-15), a pro-inflammatory cytokine has been studied as a possible marker of Alzheimer's disease (AD); however its exact role in neuro-inflammation or the pathogenesis AD is not well understood yet. | 25710473 |
| Adenocarcinoma, Inflammation, Serrated adenocarcinoma | Altered Intercellular Communication | Moreover, morphologic features significantly associated with BRAF mutation were: serrated adenocarcinoma subtype, adenocarcinomas with a mucinous component, high histologic grade, pushing margins, stromal inflammation. | 25710585 |
| Interictal epileptiform activity | Altered Intercellular Communication | Periodic lateralized epileptiform discharges may arise by synchronization of preexisting local field potentials, through a variable combination of enhancement of excitatory neurotransmission and inactivation of inhibitory neurotransmission provoked by the PLED-associated disease process. | 25710632 |
| Vasculitis, Leukocytoclastic, Cutaneous, Inflammation, Purpura | Altered Intercellular Communication | Leukocytoclastic vasculitis (LCV), a disease characterized by inflammation of the small vessels, presents with palpable purpura, especially in the lower extremities. | 25711253 |
| Allergic sensitization, Inflammation | Altered Intercellular Communication | Both facilitated allergen sensitization and secondary degradation of filaggrin following T-helper cell 2 inflammation might be key elements to understanding this relationship. | 25712346 |
| Inflammation, Primary malignant neoplasm, Hypoxia | Altered Intercellular Communication | Excess visceral adipose tissue may promote cancer development and progression via an obesity-related metabolic derangements, including adipocytokine-related inflammation, insulin resistance, and hypoxia. | 25712800 |
| Inflammation, Primary malignant neoplasm | Altered Intercellular Communication | Regular aspirin use may decrease cancer risk by reducing chronic inflammation. | 25713025 |
| Inflammation, Primary malignant neoplasm | Altered Intercellular Communication | Additional studies are needed to better understand the relationship between aspirin use, chronic inflammation, and cancer risk. | 25713025 |
| Inflammation, Colorectal Carcinoma | Altered Intercellular Communication | Neopterin may be relevant for colorectal cancer (CRC) development, as a biomarker of cellular immune activity exerting pleiotropic effects on cellular ageing, oxidative stress, and inflammation. | 25713165 |
| Inflammation, Blood Clot | Altered Intercellular Communication | Moreover, the nonhomogeneous ISR image visualized by OCT may show chronic inflammation and fibrin thrombi. | 25714072 |
| Hypernatremia, Inflammation, physiopathological, Obesity, Diabetes Mellitus, Non-Insulin-Dependent | Altered Intercellular Communication | Lipid overload in obesity and type 2 diabetes is associated with adipocyte dysfunction, inflammation, macrophage infiltration, and decreased fatty acid oxidation (FAO). | 25714670 |
| Inflammation, Comorbidity | Altered Intercellular Communication | Within-person variation was unaffected by dialysis modality, hydration status, inflammation, or cardiac comorbidity. | 25714960 |
| Esophageal Stricture, Inflammation, Acid reflux | Altered Intercellular Communication | We present a novel finding of multinucleated histiocytes associated with acute and chronic inflammation secondary to gastroesophageal reflux in a patient with a history of esophageal stricture, representing the first documented case after a review of the literature. | 25715818 |
| Fibrosis Assessment, Pneumonitis | Altered Intercellular Communication | The rats exposed to PHMG-phosphate aerosol particles in nanometer size showed pulmonary inflammation and fibrosis including inflammatory cytokines and fibronectin mRNA increase, as well as histopathological changes. | 25716161 |
| Destruction of tissue, Inflammation | Altered Intercellular Communication | A simultaneous state of tissue destruction and inflammation caused by PHMG-phosphate had whipped up a "perfect storm" in the respiratory tract. | 25716161 |
| Inflammation, Fibrosis Assessment | Altered Intercellular Communication | Factors such as inflammation, the presence of heart fibrosis, stress and cardiomyocyte apoptosis, have all been associated with AF. | 25716679 |
| Vasculitis | Altered Intercellular Communication | The existing donor-specific antibodies or moderate microvascular inflammation or C4d-positive staining or intensive tubulointerstitial inflammation played a less significant role on the long-term graft survival. | 25719260 |
| Inflammation, Overweight | Altered Intercellular Communication | Glucosamine and chondroitin supplementation may lower systemic inflammation and alter other pathways in healthy, overweight individuals. | 25719429 |
| Inflammation, Primary malignant neoplasm | Altered Intercellular Communication | Inflammation is critical to the pathogenesis and progression of cancer, with a high neutrophil-lymphocyte ratio (NLR) associated with poor prognosis. | 25719834 |
| Communicable Diseases, Inflammation | Altered Intercellular Communication | Focal exuberant soft-tissue proliferation around the buckle was present in all patients, suggesting chronic inflammation and infection. | 25719983 |
| Granulomatous inflammation, Endophthalmitis | Altered Intercellular Communication | Evaluation of the 16 enucleated inciting eyes (blind and painful) disclosed that 9 of the 16 had typical histology, fulfilling the criteria for sympathetic ophthalmia of diffuse granulomatous inflammation. | 25719985 |
| Granulomatous inflammation, Necrosis | Altered Intercellular Communication | Many lymph nodes showed histologic findings of granulomatous inflammation with necrosis. | 25720029 |
| Inflammation, Data types - Address | Altered Intercellular Communication | Inflammation and immune alterations have been linked to AD, suggesting that the peripheral immune system plays a role during the asymptomatic period of AD. | 25720398 |
| Mastitis, Menopause | Altered Intercellular Communication | Menopause is a determinant of breast adipose inflammation. | 25720743 |
| Inflammation, Malignant Neoplasms | Altered Intercellular Communication | Chronic inflammation is recognized as a risk factor for the development of several malignancies. | 25720743 |
| Inflammation, Malignant neoplasm of breast | Altered Intercellular Communication | The associated increased levels of aromatase in the breast provide a plausible mechanistic link between WAT inflammation and estrogen-dependent breast cancers. | 25720743 |
| Mastitis, Neoplasms | Altered Intercellular Communication | Thus, breast WAT inflammation could be relevant for explaining the high incidence of estrogen-dependent tumors with aging despite diminished circulating estrogen levels after menopause. | 25720743 |
| Mastitis | Altered Intercellular Communication | In multivariable analyses adjusted for BMI, the postmenopausal state was independently associated with the presence (P = 0.03) and severity of breast WAT inflammation (P = 0.01). | 25720743 |
| Mastitis | Altered Intercellular Communication | Our findings demonstrate that breast WAT inflammation, which is associated with elevated aromatase levels, is increased in association with the postmenopausal state independent of BMI. | 25720743 |
| Mastitis, Neoplasms | Altered Intercellular Communication | Breast WAT inflammation, a process that can potentially be targeted, may help to explain the high incidence of estrogen-dependent tumors in postmenopausal women. | 25720743 |
| Inflammation, Breast Carcinoma | Altered Intercellular Communication | Immediate postoperative inflammation is an important prognostic factor in breast cancer. | 25721153 |
| Inflammation, Primary malignant neoplasm | Altered Intercellular Communication | Inflammation is associated with worse outcomes in cancer. | 25721153 |
| Inflammation, Breast Carcinoma | Altered Intercellular Communication | Immediate postoperative inflammation is an important prognostic marker in breast cancer patients. | 25721153 |
| Inflammation, Degenerative disorder | Altered Intercellular Communication | The rate of inflammation increases in elderly individuals, a phenomenon called inflammaging, and is associated with degenerative diseases. | 25721217 |
| Inflammation | Altered Intercellular Communication | Number of sons contributes to ageing-associated inflammation. | 25721217 |
| Inflammation, Degenerative disorder | Altered Intercellular Communication | The rate of inflammation increases in elderly individuals, a phenomenon called inflammaging, and is associated with degenerative diseases. | 25721217 |
| Inflammation, Intradermal Route of Drug Administration | Altered Intercellular Communication | Using the higher SF cut-off method resulted in the highest ID prevalence (52.1%), followed by using two different cut-offs (31.8%), using CFs (21.9%) and excluding subjects with inflammation (17.6%). | 25721990 |
| Fatty Liver, Inflammation, Metabolic Diseases, Obesity | Altered Intercellular Communication | Obesity is a major risk factor for many chronic metabolic diseases such as inflammation, insulin resistance (IR) and fatty liver injury. | 25723054 |
| Inflammation, Nasal Polyps, Chronic sinusitis | Altered Intercellular Communication | Our results suggest that SpA can regulate the pathogenesis of enterotoxin-induced inflammation in patients with chronic rhinosinusitis with nasal polyps through coupling to immunoglobulins. | 25724120 |
| Inflammation, Demyelination, MS gene, response to axon injury | Altered Intercellular Communication | Differentiation and quantification of inflammation, demyelination and axon injury or loss in multiple sclerosis. | 25724201 |
| Inflammation, Demyelination, Multiple Sclerosis, Pathology | Altered Intercellular Communication | Axon injury/loss, demyelination and inflammation are the primary pathologies in multiple sclerosis lesions. | 25724201 |
| Inflammation, Demyelination, MS gene | Altered Intercellular Communication | An imaging modality capable to effectively detect, differentiate and individually quantify axon injury/loss, demyelination and inflammation, would not only facilitate the understanding of the pathophysiology underlying multiple sclerosis progression, but also the assessment of treatments at the clinical trial and individual patient levels. | 25724201 |
| Vasogenic Edema | Altered Intercellular Communication | Through the multiple-tensor modelling of diffusion weighted magnetic resonance imaging signals, diffusion basis spectrum imaging resolves inflammation-associated cellularity and vasogenic oedema in addition to accounting for partial volume effects resulting from cerebrospinal fluid contamination, and crossing fibres. | 25724201 |
| Edema | Altered Intercellular Communication | Diffusion basis spectrum imaging-derived radial diffusivity (myelin integrity marker) and non-restricted isotropic diffusion fraction (oedema marker) correlated with magnetization transfer ratio, supporting previous reports that magnetization transfer ratio is sensitive not only to myelin integrity, but also to inflammation-associated oedema. | 25724201 |
| Inflammatory disease of mucous membrane, Protein-Losing Enteropathies | Altered Intercellular Communication | An abdominal dynamic scintigraphy and colonoscopy findings indicated protein-losing enteropathy with nonspecific mucosal inflammation. | 25724370 |
| Inflammation, Sleep Apnea, Obstructive | Altered Intercellular Communication | Effects of nondipping pattern on systemic inflammation in obstructive sleep apnea. | 25724552 |
| Inflammation | Altered Intercellular Communication | These results demonstrate that MAA adducts are associated with AAA and suggest that they may play a role in either initiating or propagating chronic inflammation in AAA. | 25724613 |
| Myocarditis | Altered Intercellular Communication | Although this might reflect continued emotional stress, myocardial inflammation and accentuated brain-type natriuretic peptide (BNP) release persist for at least 3 months. | 25724780 |
| Myocarditis | Altered Intercellular Communication | In conclusion, despite normalization of left ventricular ejection fraction, GLS remains impaired for at least 3 months, possibly as a result of residual myocardial inflammation. | 25724780 |
| Inflammation, Dental Plaque | Altered Intercellular Communication | Examination demonstrated a fluffy white infiltrate and epithelial defect with subsequent endothelial plaque formation and anterior chamber inflammation. | 25725025 |
| Respiratory complication, Inflammation, Airway structure, Fibrosis Assessment, Hemoptysis | Altered Intercellular Communication | Cystic fibrosis (CF) is characterized by airway infection and inflammation resulting in respiratory complications including hemoptysis. | 25725985 |
| Inflammation, Metabolic Diseases, Chronic Kidney Diseases | Altered Intercellular Communication | Protein calorie malnutrition as well as systemic inflammation and metabolic disorders are common among patients with chronic renal failure undergoing renal replacement therapy (haemodialysis), which contributes to its morbidity and mortality. | 25726228 |
| Inflammation, Chronic Kidney Diseases | Altered Intercellular Communication | Assessment of the reliability and consistency of the "malnutrition inflammation score" (MIS) in Mexican adults with chronic kidney disease for diagnosis of protein-energy wasting syndrome (PEW). | 25726233 |
| Inflammation, Malnutrition, Anorexia, Cachexia, Chronic Kidney Diseases | Altered Intercellular Communication | The protein-energy wasting syndrome (PEW) is a condition of malnutrition, inflammation, anorexia and wasting of body reserves resulting from inflammatory and non-inflammatory conditions in patients with chronic kidney disease (CKD).One way of assessing PEW, extensively described in the literature, is using the Malnutrition Inflammation Score (MIS). | 25726233 |
| Inflammation, Malnutrition, Anorexia, Cachexia, Chronic Kidney Diseases | Altered Intercellular Communication | The protein-energy wasting syndrome (PEW) is a condition of malnutrition, inflammation, anorexia and wasting of body reserves resulting from inflammatory and non-inflammatory conditions in patients with chronic kidney disease (CKD).One way of assessing PEW, extensively described in the literature, is using the Malnutrition Inflammation Score (MIS). | 25726233 |
| Inflammation, Rectocolitis, Ulcerative | Altered Intercellular Communication | Ulcerative rectocolitis is characterized by diffuse mucosal inflammation and oxidative stress. | 25726244 |
| Refractory anemias, Inflammation, Ischemic stroke | Altered Intercellular Communication | A better control of inflammation by new anti-rheumatic treatments will protect the RA patients of deleterious effects of ischemic stroke. | 25726631 |
| Inflammation, Tumor necrosis | Altered Intercellular Communication | There was a significant increase in the activity/content of acute inflammation stage proteins: a1-proteinase inhibitor and C-reactive protein as well as anti-inflammatory interleukin-10 compared to the controls while the activity of other inflammatory molecules (leukocyte elastase, tumor necrosis factor alpha, interleukin-1 receptor antagonist) was not changed. | 25726782 |
| Inflammation, Schizophrenia | Altered Intercellular Communication | The results suggest that inflammation does not play a significant role in the remote stages of schizophrenia, in contrast to earlier stages of the disease, and the activity of the pathological process decreased in the late stages. | 25726782 |
| Inflammation | Altered Intercellular Communication | Acute and chronic inflammation was present around the salivary gland. | 25727303 |
| Inflammation | Altered Intercellular Communication | Not only are instances of symptomatic ectopic salivary glands rare, but this was also the first case detected to be caused by the pathophysiology involving the leakage of secretions from an ectopic salivary gland and associated inflammation. | 25727303 |
| Inflammation, Hyperlipidemia | Altered Intercellular Communication | Simvastatin treatment could inhibit inflammation and senescence-associated genes in older patients with hyperlipidemia, suggesting its application in inflammatory and age-related diseases. | 25727911 |
| Bacteremia, Inflammation | Altered Intercellular Communication | Lipid mediators of inflammation as novel plasma biomarkers to identify patients with bacteremia. | 25727996 |
| Bacteremia, Inflammation | Altered Intercellular Communication | Plasma lipid mediators of inflammation can distinguish bacteremia cases from non-bacteremia controls. | 25727996 |
| Inflammation, Apathy, Depression, CTCAE | Altered Intercellular Communication | Low-grade inflammation differentiates between symptoms of apathy and depression in community-dwelling older individuals. | 25729001 |
| Inflammation, Apathy, Depression, CTCAE | Altered Intercellular Communication | Systemic low-grade inflammation has repeatedly been associated with depression in old age, but the relationship with apathy is less clear. | 25729001 |
| Inflammation, Apathy, Depression, CTCAE | Altered Intercellular Communication | This suggests a differential effect of inflammation on apathy and depression. | 25729001 |
| Inflammation, Apathy | Altered Intercellular Communication | In older persons, symptoms of apathy may be a behavioral manifestation of concurrent low-grade inflammation. | 25729001 |
| Autoimmune Diseases, Inflammation, polychondritis | Altered Intercellular Communication | Relapsing polychondritis is a rare autoimmune disease characterized by inflammation of cartilaginous tissues. | 25729816 |
| Inflammation | Altered Intercellular Communication | Increased inflammation and oxidative stress, as well as decreased secretion of cardiac protective factors, may be associated with the simultaneous onset of HHD and CAD. | 25729940 |
| Refractory anemias, Inflammation | Altered Intercellular Communication | Deregulation of the MEFV gene is likely to result in uncontrolled inflammation as observed in RA. | 25730039 |
| Inflammation, Bacterial Infections | Altered Intercellular Communication | Visual analogue scale of ear complaints, cavity inflammation, and bacterial infection. | 25730446 |
| Delirium, Inflammation, Osteochondritis Dissecans | Altered Intercellular Communication | The mechanism of POCD and delirium has been suggested to be associated with inflammation, but its details are unknown. | 25731050 |
| Inflammation, Primary malignant neoplasm, Endometriosis | Altered Intercellular Communication | Excluded cases with other cancer or previous cancer treatment, major abdominal pathology or inflammation, endometriosis. | 25731151 |
| Inflammation | Altered Intercellular Communication | After the inflammation improved by abscess drainage, we conducted ileocecal resection and fenestrated the abscess. | 25731289 |
| Inflammation, Necrosis | Altered Intercellular Communication | Pathological examination of the surgical specimen revealed autolysis of the superficial layer with progression to necrosis and associated inflammation. | 25731411 |
| Secondary malignant neoplasm of lung, Secondary malignant neoplasm of liver, Inflammation, Intrahepatic bile duct | Altered Intercellular Communication | However, after completion of the first course of treatment, the patient experienced exacerbation of the liver metastases, pulmonary metastasis, and inflammation of the intrahepatic bile ducts. | 25731545 |
| Inflammation, Liver carcinoma, FAM126A gene | Altered Intercellular Communication | Inflammation is particularly strong in huge hepatocellular carcinoma (HCC). | 25731733 |
| Inflammation, Neoplasms | Altered Intercellular Communication | However, histology showed no tumor recurrence, but strong inflammation and foreign-body reaction towards Dermabond. | 25731826 |
| Inflammation, Data types - Address, Pathology | Altered Intercellular Communication | In AD mice deficient for TREM2, the CD45(hi)Ly6C(+) macrophages are virtually eliminated, resulting in reduced inflammation and ameliorated amyloid and tau pathologies. | 25732305 |
| Inflammation Mediators | Altered Intercellular Communication | NOD1 is an intracellular immune receptor that senses peptidoglycan from Gram-negative bacteria and responds by inducing autophagy and activating NF-kB, leading to inflammation-mediated bacterial clearance; however chronic pathogens can evade NOD1-mediated clearance by altering peptidoglycan structure. | 25732381 |
| Inflammation, Malignant Lesion, Primary malignant neoplasm | Altered Intercellular Communication | Infection of Mongolian gerbils with an H. pylori pgdA(-) mutant strain led to significantly decreased levels of inflammation and malignant lesions in the stomach; however, preactivation of NOD1 before bacterial challenge reciprocally suppressed inflammation and cancer in response to wild-type H. pylori. | 25732381 |
| Inflammation, Diabetes Mellitus | Altered Intercellular Communication | The stimulus for the increase in inflammation in diabetes is still under investigation; however, reactive oxygen species might be a primary source. | 25732517 |
| Hemorrhagic Fever, Crimean, Inappropriate ADH Syndrome | Altered Intercellular Communication | Syndrome of inappropriate antidiuretic hormone associated with Crimean-Congo hemorrhagic fever. | 25732889 |
| Inflammation, Endothelial dysfunction | Altered Intercellular Communication | Reasons for this high co-prevalence include endothelial dysfunction, inflammation, oxidative and emotional stress associated with AF. | 25733318 |
| Inflammation, Endothelial dysfunction, Cardiovascular Diseases | Altered Intercellular Communication | A healthy diet is associated with less endothelial dysfunction and less low-grade inflammation over a 7-year period in adults at risk of cardiovascular disease. | 25733469 |
| Inflammation, Endothelial dysfunction | Altered Intercellular Communication | Endothelial dysfunction and low-grade inflammation play important roles in CVD. | 25733469 |
| Inflammation, Thrombosis, Endothelial dysfunction | Altered Intercellular Communication | These data suggest that the dietary modification of endothelial dysfunction and low-grade inflammation, processes that are important in atherothrombosis, is possible. | 25733469 |
| Acquired Immunodeficiency Syndrome, HIV Infections | Altered Intercellular Communication | Conversely, markers of HIV infection, current CD4 or CD8 values, CD4 nadir, CD4/CD8 ratio, AIDS stage at initiation of PIs, current viral load and duration of ART were not associated with immune activation/inflammation markers. | 25733587 |
| Inflammation, Anemia | Altered Intercellular Communication | Anemia results from inflammation, preventing iron recycling and decreasing dietary iron absorption. | 25733630 |
| Ancylostomatoidea, Inflammation, Schistosoma hematobium infection, Malaria, hepcidin | Altered Intercellular Communication | The objective was to measure inflammation biomarkers, hepcidin, iron absorption, and utilization pre- and posttreatment in children with afebrile malaria, hookworm, and Schistosoma haematobium infection. | 25733630 |
| Inflammation, Malaria, hepcidin | Altered Intercellular Communication | Treatment of afebrile malaria reduced inflammation (P < 0.001) and serum hepcidin (P = 0.004) and improved iron absorption (P = 0.003). | 25733630 |
| Inflammation, Hookworm Infections, hepcidin | Altered Intercellular Communication | In school-age children, hookworm infection does not produce inflammation or increase serum hepcidin, and it does not influence iron absorption or utilization. | 25733630 |
| Inflammation, Malaria | Altered Intercellular Communication | In contrast, afebrile malaria causes inflammation, increases hepcidin, and reduces iron absorption but not utilization. | 25733630 |
| HD Term Type, Inflammation | Altered Intercellular Communication | Expressions of proteins for neuroprotection, angiogenesis, and inflammation in the brain tissue of R6/2 HD mice were compared by using immunostaining and Western blotting techniques. | 25733809 |
| Neurodegenerative Disorders, HD Term Type, Ototoxicity, Inflammation | Altered Intercellular Communication | We suggest that the herbal formula B401 can be developed as a medical supplement for ameliorating neurodegenerative diseases of HD via reducing mutant huntingtin aggregation and excitotoxicity, enhancing neuroprotection and angiogenesis, and alleviating inflammation in the brain. | 25733809 |
| Inflammation, Squamous cell carcinoma | Altered Intercellular Communication | Manuka honey proved a safe, effective, palliative treatment to reduce odor and inflammation in wounds secondary to squamous cell carcinoma of the oral cavity in this patient. | 25734464 |
| Inflammation | Altered Intercellular Communication | Kidney-specific accumulation was found in Ga scintigraphy, which suggested chronic inflammation. | 25735087 |
| Deficiency of testosterone biosynthesis | Altered Intercellular Communication | Hypoandrogenism is common among infertile men, and routine hormonal evaluation may identify hypoandrogenism in many infertile men with otherwise normal semen analysis. | 25735445 |
| Inflammation, Hypertrophy | Altered Intercellular Communication | Chronic inflammation is thought to cause ligamentum flavum (LF) degeneration and hypertrophy in lumbar spinal canal stenosis (LSCS). | 25735609 |
| Inflammation, Abnormal degeneration, Hypertrophy | Altered Intercellular Communication | Angptl2 promotes inflammation in LF tissue by activating IL-6 expression, leading to LF degeneration and hypertrophy. | 25735609 |
| Inflammation, Obesity | Altered Intercellular Communication | Inflammation but not obesity or insulin resistance is associated with increased plasma fibroblast growth factor 23 concentration in the elderly. | 25736796 |
| Necrotizing granulomatous inflammation | Altered Intercellular Communication | Microscopic examination of the lungs following post-mortem examination revealed occlusive granulomatous inflammation of the pulmonary arterial vasculature by crystalline material. | 25737334 |
| Autoimmune Diseases, Inflammation, Lupus Erythematosus, Lupus Erythematosus, Systemic | Altered Intercellular Communication | Systemic lupus erythematosus (SLE) is an autoimmune disease characterized by chronic inflammation. | 25738154 |
| Inflammation, Capillaritis | Altered Intercellular Communication | Focal and diffuse peritubular capillaritis (inflammation over 50% of cortical peritubular capillaries) was diagnosed in 10.5 or 14.4% of cases, respectively. | 25738252 |
| Inflammation | Altered Intercellular Communication | Inflammation is an important factor in the pathogenesis of FA cardiomyopathy but may be more evident in advanced stages of the disease. | 25738292 |
| Inflammatory disease of mucous membrane | Altered Intercellular Communication | A longer disease remission, previous less severe mucosal inflammation, and immunosuppressant use are associated with MH. | 25738375 |
| Inflammation, Fever, CTCAE | Altered Intercellular Communication | The predictive value of C-reactive protein and erythrocyte sedimentation rate for 18F-FDG PET/CT outcome in patients with fever and inflammation of unknown origin. | 25738560 |
| Inflammation, Fever, CTCAE | Altered Intercellular Communication | In patients with fever of unknown origin or inflammation of unknown origin, compared with elevated ESR levels, elevated CRP levels more often indicate a true positive (18)F-FDG PET/CT outcome.In addition, (18)F-FDG PET/CT, compared with CRP and ESR, shows the highest discrimination of patients with possible disabling disease. | 25738560 |
| Brucellosis | Altered Intercellular Communication | Cytokines play a critical role in the regulation of the immune response against brucellosis infection, and mediate production of many pro- and anti-inflammatory signals. | 25738611 |
| Inflammation, Neoplasms | Altered Intercellular Communication | The present findings suggest that inflammation may promote angiogenesis and consequently contribute to tumor progression. | 25738867 |
| Autistic Disorder | Altered Intercellular Communication | Prediction of autism by translation and immune/inflammation coexpressed genes in toddlers from pediatric community practices. | 25739104 |
| Inflammation, Hypertension, CTCAE, Atherosclerosis | Altered Intercellular Communication | T cell-driven inflammation in human hypertension and atherosclerosis has recently been revealed. | 25739534 |
| Inflammation, Malignant neoplasm of endometrium | Altered Intercellular Communication | Inflammation may be important in endometrial cancer development. | 25739930 |
| Inflammation, Primary malignant neoplasm | Altered Intercellular Communication | Long-chain o-3 (n-3) polyunsaturated fatty acids (LCo-3PUFAs) may reduce inflammation and, therefore, reduce cancer risk. | 25739930 |
| Inflammation, Malignant neoplasm of endometrium | Altered Intercellular Communication | Because body mass is associated with both inflammation and endometrial cancer risk, it may modify the association of fat intake on risk. | 25739930 |
| Myocarditis | Altered Intercellular Communication | Five patients had nonischemic late gadolinium enhancement (LGE) lesions within the left ventricular (LV) myocardium, and 3 patients demonstrated CMR evidence of myocardial inflammation. | 25740233 |
| Fibrous, Inflammation, Dental Plaque, Coronary heart disease | Altered Intercellular Communication | %CD14 and %CD163 had a significant positive correlation with %NC (%CD14: r = 0.40, P = 0.01 and %CD163: r = 0.45, P = 0.01), but only %CD163 was negatively correlated with %Fibrous (%CD163: r = -0.48, P = 0.01).These findings suggest that the presence of CD14- and CD163-positive macrophages may reflect plaque inflammation, NC expansion, and plaque vulnerability in patients with coronary heart disease. | 25740391 |
| Inflammation, Malnutrition | Altered Intercellular Communication | Transthyretin (TTR), a sensitive indicator of malnutrition and inflammation, has been shown to be associated with mortality in elderly population. | 25740746 |
| Inflammation | Altered Intercellular Communication | Subclinical low-grade inflammation, elevated serum copper and decreased hemoglobin were associated with decreased serum TTR in community-living elderly Japanese women and may represent important confounders of the relationship between low TTR and mortality in the elderly. | 25740746 |
| Inflammation, Hepatitis B | Altered Intercellular Communication | Hepatitis B virus and hepatitis C virus do not cause aggressive activation of an oncogenic pathway, but they transactivate a broad array of genes, cause chronic inflammation, and, through interference with mitotic processes, lead to mitotic error-induced chromosome instability (ME-CIN). | 25740822 |
| Colorectal Carcinoma | Altered Intercellular Communication | The metabolism of PUFAs may play an important role in the evolution of inflammation-driven tumorigenesis in CRC and may be considered a potential marker for prognosis. | 25741148 |
| Sepsis, Inflammation, Inflammatory disorder | Altered Intercellular Communication | Mean platelet volume (MPV) is suggested as an index of inflammation, disease activity, and anti-inflammatory treatment efficacy in chronic inflammatory disorders; however, the effect of MPV on sepsis mortality remains unclear. | 25742300 |
| Inflammation, Glomerulonephritis | Altered Intercellular Communication | Urinary thrombin: a novel marker of glomerular inflammation for the diagnosis of crescentic glomerulonephritis (prospective observational study). | 25742509 |
| Inflammation, Glomerulonephritis | Altered Intercellular Communication | Crescentic glomerulonephritis (CresGN), an uncommon rapidly progressive disease, is characterized by severe glomerular inflammation with fibrin deposition. | 25742509 |
| Inflammation, Observation Method - Coagulation | Altered Intercellular Communication | Thrombinuria was specific for glomerular inflammation, was unaffected by systemic inflammation or coagulation, and demonstrated good diagnostic accuracy for CresGN including ANCA-negative cases. | 25742509 |
| Inflammation, Gall Bladder Diseases | Altered Intercellular Communication | Gallbladder disease is highly related to inflammation, but the inflammatory processes are not well understood. | 25743242 |
| Chorioretinitis, Intraocular inflammation, Inflammation | Altered Intercellular Communication | At initial ocular examination (baseline), 30 patients (9.9%) had intraocular inflammation only (anterior chamber cells and flare, vitreous inflammatory reactions, retinal whitening), without clinically apparent necrotizing retinochoroiditis. | 25743338 |
| Alzheimers Disease", vascular inflammations | Altered Intercellular Communication | The amyloid beta peptide is the major protein constituent of neuritic plaques in Alzheimer disease and appears to play a central role in vascular inflammation pathophysiology. | 25744007 |
| Autoimmune Diseases, Inflammation, Pericarditis, CTCAE | Altered Intercellular Communication | Pleuritis and pericarditis, inflammation of the pleura and pericardium, may represent manifestations of autoimmune disorders especially in female subjects. | 25744068 |
| Allergy - Charge Type Reason | Altered Intercellular Communication | Interleukin 10 (IL-10) is an immunoregulatory cytokine with biological functions of anti-inflammation, immunosuppression, allergy, and anti-agenesis. | 25744234 |
| Inflammatory Bowel Diseases | Altered Intercellular Communication | Inflammatory bowel disease is a group of chronic inflammatory conditions affecting gastrointestinal tract. | 25744728 |
| Inflammation, Glaucoma, CTCAE | Altered Intercellular Communication | Despite typical POV architecture was preserved, signs of inflammation were found in glaucoma groups. | 25744981 |
| Inflammation, Vascular Diseases, Atherosclerosis | Altered Intercellular Communication | Relationship of cigarette smoking with inflammation and subclinical vascular disease: the Multi-Ethnic Study of Atherosclerosis. | 25745060 |
| Inflammation, Cardiovascular Diseases, Atherosclerosis | Altered Intercellular Communication | We sought to assess the impact of smoking status, cumulative pack-years, and time since cessation (the latter in former smokers only) on 3 important domains of cardiovascular disease: inflammation, vascular dynamics and function, and subclinical atherosclerosis. | 25745060 |
| vascular inflammations, Hypertensive (finding), Damage | Altered Intercellular Communication | The relationship between vascular inflammation and target organ damage in hypertensive crises. | 25745795 |
| vascular inflammations | Altered Intercellular Communication | Monocyte chemoattractant protein-1 (MCP-1) is responsible for the recruitment of monocytes to sites of vascular inflammation. | 25745795 |
| vascular inflammations, Hypertensive (finding), Terminal Osseous Dysplasia and Pigmentary Defects | Altered Intercellular Communication | According to our results, we suggest that increased vascular inflammation and MCP-1 levels might be associated with the development of TOD in hypertensive crisis. | 25745795 |
| NCI CTEP SDC Myelodysplastic Syndrome Sub-Category Terminology, Inflammation, Miller Dieker syndrome, Vasculitis, CTCAE | Altered Intercellular Communication | Paraneoplastic inflammation of the large vessels is a rare complication of myelodysplastic syndrome (MDS), and patients with MDS and systemic vasculitis have a poor prognosis. | 25745966 |
| Inflammation | Altered Intercellular Communication | Longitudinal assessment of inflammation in recipients of continuous-flow left ventricular assist devices. | 25746024 |
| Inflammation | Altered Intercellular Communication | Despite improvements in LV dimensions and BNP levels, markers of inflammation remained higher in CF-LVAD recipients. | 25746024 |
| Inflammation, Heart failure | Altered Intercellular Communication | High levels of inflammation in CF-LVAD recipients may result from heart failure preconditioning or the long-term device support, or both. | 25746024 |
| Inflammation | Altered Intercellular Communication | Because inflammation may be detrimental to CF-LVAD recipients, future studies should determine whether inflammatory pathways are reversible. | 25746024 |
| Inflammation, Chronic heart failure, Congestive heart failure | Altered Intercellular Communication | Ceramide is involved in apoptosis, inflammation, and stress responses, which are among the pathogenic components of chronic heart failure (CHF). | 25746025 |
| Inflammation, Giant Cell Arteritis | Altered Intercellular Communication | A biopsy of superficial temporal artery showed the characteristic findings of glanulomatous inflammation indicative of giant cell arteritis. | 25746074 |
| Inflammation | Altered Intercellular Communication | Magnetic resonance imaging of the brain early in his illness showed focal inflammation in the periaqueductal gray matter and hypothalamus. | 25746964 |
| neutrophilic, Asthma, Inflammation | Altered Intercellular Communication | TH17 cells and gd-17 cells, proposed drivers of neutrophilic inflammation, were not strongly associated with asthma, even in severe neutrophilic forms. | 25746968 |
| Inflammation, Brain Injuries, Dental Plaque, "Alzheimers Disease | Altered Intercellular Communication | The effect of focal brain injury on beta-amyloid plaque deposition, inflammation and synapses in the APP/PS1 mouse model of Alzheimer's disease. | 25747037 |
| Cessation of life, Inflammation, Necrosis | Altered Intercellular Communication | Receptor-interacting protein kinase-3 (RIP3 or RIPK3) is an essential part of the cellular machinery that executes "programmed", or "regulated", necrosis and has a key role in spontaneous cell death and inflammation in keratinocytes under certain conditions. | 25748555 |
| Inflammation, Dyssomnias | Altered Intercellular Communication | Sleep disturbance is associated with activation of systemic and cellular inflammation, as well as proinflammatory transcriptional profiles in circulating leukocytes. | 25748580 |
| Inflammation, Sleeplessness | Altered Intercellular Communication | Whether treatments that target insomnia-related complaints might reverse these markers of inflammation in older adults with insomnia is not known. | 25748580 |
| Sleeplessness, Inflammation | Altered Intercellular Communication | Among older adults with insomnia, CBT-I reduced systemic inflammation, TCC reduced cellular inflammatory responses, and both treatments reduced expression of genes encoding proinflammatory mediators. | 25748580 |
| Sleeplessness, Inflammation, Inflammatory disorder | Altered Intercellular Communication | The findings provide an evidence-based molecular framework to understand the potential salutary effects of insomnia treatment on inflammation, with implications for inflammatory disease risk. | 25748580 |
| Inflammation, Primary malignant neoplasm | Altered Intercellular Communication | An increased faecal load in the colon with or without delayed transit will increase bacterial counts and create a chronic inflammation of the colonic mucosa, which is a risk factor for cancer onset. | 25748875 |
| Breast Carcinoma, Inflammation, Sleeplessness | Altered Intercellular Communication | Tai chi, cellular inflammation, and transcriptome dynamics in breast cancer survivors with insomnia: a randomized controlled trial. | 25749595 |
| Inflammation, Hypercapnia | Altered Intercellular Communication | Under intravenous anesthesia, therapeutic hypercapnia inhibits local and systematic inflammation and improves respiratory function after OLV in lobectomy patients without severe complications. | 25751232 |
| Structure of lamina episcleralis, Exophthalmos, Orbital Pseudotumor, Carotid-Cavernous Sinus Fistula | Altered Intercellular Communication | A 4-month-old male infant with proptosis and episcleral injection initially thought to have orbital inflammation was found to have an indirect carotid-cavernous sinus fistula. | 25751239 |
| Refractory anemias, Inflammation, Damage | Altered Intercellular Communication | Therefore, we aimed to examine the effects of ALA on serum biomarkers of joint damage and inflammation in women with RA. | 25751300 |
| Atrophic, Necrosis | Altered Intercellular Communication | Muscle biopsy showed necrotic fibers, focal sparse perivascular inflammation/perifascicular atrophy, endomysial/epimysial vessel wall thickening with luminal narrowing. | 25751473 |
| ARCN1 gene, Communicable Diseases, Pneumonitis | Altered Intercellular Communication | Infected mice with experimental COPD also had more severe infection (increased viral titer and pulmonary inflammation, and compromised lung function). | 25751541 |
| Inflammation, Vitreous strands | Altered Intercellular Communication | The number of vitreous cells increased significantly in the cases with clinically active inflammation (2297 versus 207 cells/ml, respectively, p < 0.01, Mann-Whitney U-test). | 25752226 |
| Vasculitis | Altered Intercellular Communication | However, inhibition of 5-LO with VIA-2291 is not associated with significant reductions in vascular inflammation (by FDG-PET) or in blood inflammatory markers. | 25752438 |
| Communicable Diseases, Helicobacter pylori, Inflammation, Peptic Ulcer | Altered Intercellular Communication | The eradication rate of Helicobacter pylori (H. pylori) infection might be affected by the degree of inflammation of gastric mucosa represented by the endoscopic stage of peptic ulcer disease (PUD). | 25752487 |
| Inflammation, Observation Method - Coagulation, Prediabetes syndrome, Endothelial dysfunction | Altered Intercellular Communication | Inflammation, coagulation, endothelial dysfunction and oxidative stress in prediabetes--Biomarkers as a possible tool for early disease detection for rural screening. | 25753569 |
| Inflammation, Obesity | Altered Intercellular Communication | Interventions targeting obesity might improve sedentary behavior and physical activity, whereas interventions targeting inflammation might improve physical activity in these populations. | 25753603 |
| Inflammation | Altered Intercellular Communication | Early life course inflammation and cardiovascular reactivity are important candidate pathways through which the repeated exposure to discrimination for minority group members contributes to racial and economic health inequities in adulthood. | 25753652 |
| Inflammation, ABCA4 gene, muscle mass | Altered Intercellular Communication | The decrease in fat free mass (FFM), muscle mass (MM) and increase in visceral fat is associated with an elevated secretion of cytokines which promote systemic inflammation. | 25754053 |
| ARCN1 gene, Inflammation | Altered Intercellular Communication | Body compositions abnormality and higher activity of systemic inflammation could therefore be a negative prognostic factor in COPD patients. | 25754053 |
| Inflammation, Thyroid associated opthalmopathies | Altered Intercellular Communication | Medics initially thought the presentation was related to an intracranial pathology but through subsequent tests and examination, ophthalmologists diagnosed a severe case of thyroid eye disease with intense inflammation. | 25754167 |
| Neoplasms | Altered Intercellular Communication | Macroadenoma can lead to atypical hormonal test results and complete removal of the tumour is unlikely. | 25754284 |
| Attention deficit hyperactivity disorder, Mood Disorders, Neurodevelopmental Disorders, Behavior Disorders | Altered Intercellular Communication | Models adjusted for sociodemographic correlates, other physical and mental disorders, and false discovery and revealed broad patterns of associations between neurodevelopmental disorders with behavior disorders (odds ratio [OR]: 1.5; 95% confidence interval [CI]: 1.3-1.8; P < .004) and attention-deficit/hyperactivity disorder (OR: 3.1; 95% CI: 2.7-3.6; P < .0001), and neurologic/central nervous system conditions (OR: 1.3; 95% CI: 1.1-1.9; P < .05) with mood disorders and attention-deficit/hyperactivity disorder (OR: 1.3; 95% CI: 1.1-1.5; P < .001), and autoimmune/inflammatory conditions with mood disorders (OR: 1.4; 95% CI: 1.1-1.8, P < .05). | 25755242 |
| Granulomatous inflammation, FGFR1OP gene, Acute infectious disease | Altered Intercellular Communication | With respect to secondary FOP, acute infection and granulomatous inflammation are the main causes. | 25755741 |
| Inflammation | Altered Intercellular Communication | Transforming growth factor-beta-induced (TGFBI) serves as a linker protein and plays a role in the activation of morphogenesis, cell proliferation, adhesion, migration, differentiation and inflammation. | 25755764 |
| Communicable Diseases, Xanthogranulomatous inflammation | Altered Intercellular Communication | Given that some types of xanthogranulomatous inflammation (XGI) are associated with pathogens, infection should be considered as a possible cause of XGG. | 25755811 |
| Inflammation, Plaque, Atherosclerotic | Altered Intercellular Communication | These findings suggest that MIG may be used as a novel biomarker for T-cell inflammation and atherosclerotic plaque burden in humans. | 25756330 |
| Cardiac Arrest, Inflammation | Altered Intercellular Communication | The aim was to investigate the association between level of systemic inflammation and mortality in survivors after out-of-hospital cardiac arrest treated with targeted temperature management. | 25756419 |
| Inflammation, Carcinogenesis, Malignant Neoplasms | Altered Intercellular Communication | It has been proposed that carcinogenesis is a result of asbestos-induced inflammation but it is not clear what contributes to the differences observed between incidences of these two cancers. | 25757056 |
| Gingivitis | Altered Intercellular Communication | Furthermore, there was a significant difference in Modified Gingival Index (MGI, P = 0.02) between the two groups with the study group having less gingival inflammation. | 25757137 |
| Inflammation | Altered Intercellular Communication | RAGE is a transmembrane receptor expressed on immune and endothelial cells, whose binding with its ligands, the S100 calgranulins, leads to chronic inflammation. | 25757448 |
| Sjogrens Syndrome", Inflammation | Altered Intercellular Communication | MUC1/SEC and MUC1/Y overexpression is associated with inflammation in Sjogren's syndrome. | 25757505 |
| Neurodegenerative Disorders, "Alzheimers Disease", Data types - Address, Inflammation | Altered Intercellular Communication | In addition, it has been shown that the pathogenesis of neurodegenerative disorders, such as Alzheimer's disease (AD), involves inflammation as well as oxidative stress. | 25758069 |
| Inflammation, Abnormal degeneration, Equilibration disorder | Altered Intercellular Communication | An increased calcium-phosphate product level was suspected as an etiology, although degeneration, inflammation and/or mineral balance disorders may also induce the development of CAT. | 25758074 |
| HMGCL gene | Altered Intercellular Communication | A personal prior history of chronic inflammatory condition was not associated with an increased risk of HL (0.94; 0.71-1.14). | 25758095 |
| Inflammation, Diabetic Angiopathies | Altered Intercellular Communication | Inflammation and complement activation initiated by mannose-binding lectin (MBL) may be implicated in the pathogenesis of diabetic vascular complications. | 25758771 |
| Malnutrition, HD Term Type, Inflammation | Altered Intercellular Communication | It can be concluded that, in addition to old age, malnutrition (low GNRI) and inflammation (high ferritin) are identified as significant independent risk factors that predict all-cause mortality in HD patients. | 25758879 |
| Inflammation, Endothelial dysfunction | Altered Intercellular Communication | Circulating angiogenic factors (AF) reflect tissue healing capacity, although some AF can also contribute to inflammation and are indicative of endothelial dysfunction. | 25759146 |
| Inflammation, Amyloidosis, Familial, Atherosclerosis | Altered Intercellular Communication | In contrast to hereditary amyloidosis, wherein specific mutations of apoA-I cause protein destabilization and amyloid deposition, oxidative conditions similar to those promoted by local inflammation in atherosclerosis are sufficient to transform full-length wild-type apoA-I into an amyloidogenic protein. | 25759391 |
| Inflammation, Diabetic foot ulcer | Altered Intercellular Communication | In conclusion, following wound bed preparation for diabetic foot ulcers, MDR bacteria numbers were increased and antibiotic sensitivity was decreased; inflammation was decreased. | 25759414 |
| Fibrosis Assessment, Hepatitis | Altered Intercellular Communication | HBsAg levels were compared among different liver inflammation grades, as well as different hepatic fibrosis stages. | 25759544 |
| Inflammation, Hepatitis B | Altered Intercellular Communication | In hepatitis B e antigen-negative chronic hepatitis B, serum HBsAg levels in liver histological inflammation grades 1-4 were 3.66 +- 0.40, 3.74 +- 0.35, 3.74 +- 0.26 and 3.71 +- 0.34 log10 COI (cut off index), respectively, and there were no differences before apportion (P = 0.640). | 25759544 |
| Fibrosis Assessment, Hepatitis | Altered Intercellular Communication | Serum HBsAg levels apportioned by the same HPCV (hepatic cell quantities), rather than serum HBsAg levels, increase with liver inflammation grades and hepatic fibrosis stages. | 25759544 |
| Inflammation, Hemorrhage, Schistosoma japonicum, Necrosis | Altered Intercellular Communication | Histopathological examination revealed mucosal necrosis and hemorrhage with a large number of infiltrating eosinophils and neutrophils, and acute submucosal inflammation with a large number of infiltrating eosinophils and neutrophils associated with Schistosoma japonicum (S. japonicum) eggs. | 25759563 |
| Inflammation | Altered Intercellular Communication | An additional 10 (29.4%) specimens contained a combination of acute and chronic inflammation. | 25760207 |
| Inflammation, Primary malignant neoplasm | Altered Intercellular Communication | Recent studies have revealed that cancer cells are exacerbated by chronic inflammation. | 25761055 |
| Inflammation, Anemia | Altered Intercellular Communication | The first axis was associated with anemia, inflammation, and low levels of calcium and albumin. | 25761112 |
| Fibrosis, Liver, Inflammation, Fibrosis Assessment | Altered Intercellular Communication | Red blood cell distribution width levels correlate with liver fibrosis and inflammation: a noninvasive serum marker panel to predict the severity of fibrosis and inflammation in patients with hepatitis B. | 25761184 |
| Fibrosis, Liver, Inflammation, Hepatitis B | Altered Intercellular Communication | A total of 446 hepatitis B virus-infected patients who underwent liver biopsy were divided into 2 groups: absent or mild and moderate-severe according to the severity of liver fibrosis and inflammation. | 25761184 |
| Inflammation, Fibrosis Assessment | Altered Intercellular Communication | The independent variables that determine the severity of liver fibrosis and inflammation were explored. | 25761184 |
| Inflammation, Fibrosis Assessment | Altered Intercellular Communication | RDW values increased with progressive liver fibrosis and inflammation. | 25761184 |
| Inflammation, Fibrosis Assessment | Altered Intercellular Communication | After adjustments for other potent predictors, liver fibrosis (moderate-severe) was independently associated with RDW, platelet, and albumin (odds ratio = 1.121, 0.987, and 0.941, respectively), whereas increased odds ratios of significant inflammation were found for RDW, alanine aminotransferase, albumin, and PLT (odds ratio = 1.146, 1.003, 0.927, and 0.990, respectively). | 25761184 |
| Hepatitis | Altered Intercellular Communication | The sensitivity and specificity of model B were 66.1% and 79.4% for predicting advanced liver inflammation (AUC = 0.765, P < 0.001). | 25761184 |
| Renal Insufficiency, Interstitial inflammation | Altered Intercellular Communication | The density of CCL18(+) cells correlated with crescent formation, interstitial inflammation, and impairment of renal function. | 25762060 |
| Nephritis | Altered Intercellular Communication | In summary, our data indicate that CCL18 drives renal inflammation through CCR8-expressing cells and could serve as a biomarker for disease activity and renal relapse in ANCA-associated crescentic GN. | 25762060 |
| Pain Distress Question, Inflammation | Altered Intercellular Communication | Based on the number of non-invasive methods, to reduce muscle tension, mute pain and alleviation of inflammation. | 25763584 |
| Inflammation, Calcification of coronary artery | Altered Intercellular Communication | Association of systemic inflammation with epicardial fat and coronary artery calcification. | 25763815 |
| Inflammation | Altered Intercellular Communication | While it is postulated to be an independent risk factor, a possible mechanism is local or systemic inflammation. | 25763815 |
| Inflammation, Atherosclerosis | Altered Intercellular Communication | We analyzed the relationship between coronary atherosclerosis, quantified by coronary calcium in CT, epicardial fat volume and systemic inflammation. | 25763815 |
| Inflammation, SLC25A20 gene | Altered Intercellular Communication | The progression of CAC was significantly correlated with the extent of EFV (P < 0.001) while there was no significant correlation between progression of EFV or CAC with systemic inflammation markers. | 25763815 |
| Inflammation, SLC25A20 gene | Altered Intercellular Communication | While both baseline EFV and CAC displayed significant correlations with systemic inflammation markers, biomarkers were not predictive of the progression of CAC or EFV. | 25763815 |
| Pneumonitis, Metapneumovirus | Altered Intercellular Communication | Human metapneumovirus infection activates the TSLP pathway that drives excessive pulmonary inflammation and viral replication in mice. | 25763996 |
| Pneumonitis | Altered Intercellular Communication | Here, we evaluated whether the thymic stromal lymphopoietin (TSLP) pathway contributes to lung inflammation upon hMPV infection. | 25763996 |
| Pain Distress Question, Inflammation | Altered Intercellular Communication | Those patients had developed symptoms of pain and local knee inflammation six years after total knee replacement. | 25764647 |
| palladium, Inflammation, Mesothelial cell | Altered Intercellular Communication | Inflammation cooperates with high GDP PD fluids to promote mesothelial cell death, which is resistant to several therapeutic approaches. | 25765663 |
| Inflammation, Metabolic Diseases, Diabetes Mellitus | Altered Intercellular Communication | Diabetes is a serious metabolic disorder and oxidative stress and inflammation contribute to its pathogenesis and complications. | 25765835 |
| vascular inflammations, Atherosclerosis | Altered Intercellular Communication | Omentin is a member of the adipokines, and has a protective effect against vascular inflammation and pathological remodeling leading to atherosclerosis as well as a vasodilatory effect. | 25766303 |
| vascular inflammations | Altered Intercellular Communication | These results suggest that a loss of omentin-dependent protection against vascular inflammation and remodeling may be related to pathological vascular events of early dcSSc. | 25766303 |
| Inflammation, Injury of cardiac valve, Myocardial Infarction, Myocardial Stunning, Ischemic | Altered Intercellular Communication | Ischaemic haemodialysis (HD)-induced cardiac injury (myocardial stunning) is common and is associated with markers of myocardial necrosis, inflammation, cardiovascular events and mortality. | 25766334 |
| Inflammation | Altered Intercellular Communication | Increased CXCL-1 levels may be indicative of mild inflammation in the detached retina and the adjacent vitreous. | 25766782 |
| Inflammation | Altered Intercellular Communication | Additionally, increased inflammation in patients with ERM probably requires more frequent injections. | 25768251 |
| Inflammation | Altered Intercellular Communication | Overall, we see a shift in the transcriptome from immunity and inflammation to repair and recovery during the course of a DENV infection. | 25768297 |
| Inflammation, Dengue Fever | Altered Intercellular Communication | Time since onset of disease associates with the shift in transcriptome signatures from immunity and inflammation to cell cycle and repair mechanisms in patients with non-severe dengue. | 25768297 |
| Communicable Diseases, Inflammation | Altered Intercellular Communication | C-reactive protein (CRP), a marker of infection and inflammation, is produced mainly in the liver. | 25769586 |
| Inflammation, Primary malignant neoplasm | Altered Intercellular Communication | The platelet-to-lymphocyte ratio (PLR) has been proposed as an easily assessable marker of systemic inflammation and has been shown to represent a prognostic marker in different cancer entities. | 25769845 |
| Inflammation, Dysautonomia | Altered Intercellular Communication | The pathophysiological mechanisms underlying this association remain poorly understood, although several candidates including inflammation, cardiac autonomic dysregulation, and behavioural factors are viewed as of key importance. | 25770081 |
| Inflammation, Coronary Arteriosclerosis | Altered Intercellular Communication | Association of serum total bilirubin level with severity of coronary atherosclerosis is linked to systemic inflammation. | 25770689 |
| Scleritis | Altered Intercellular Communication | We included a total of 30 eyes of 30 patients with unilateral anterior scleral or episcleral inflammation. | 25771347 |
| Inflammation, Chronic multifocal osteomyelitis | Altered Intercellular Communication | Histopathology demonstrated only non-specific chronic inflammation compatible with CRMO. | 25771734 |
| Tick-borne encephalitis vaccine, herpesvirus 3, human, Inflammation, Enterovirus meningitis | Altered Intercellular Communication | Ninety-six patients with clinically and laboratory proven tick-borne encephalitis (TBE) and 77 patients with a confirmed diagnosis of enteroviral meningitis (EVM), along with a control group of 107 patients without evidence of inflammation in the CSF were retrospectively tested by nested PCR for the presence of DNA of the neurotropic herpesviruses HSV1, HSV2, VZV, and HHV6 in the CSF. | 25771938 |
| Inflammation, glycation, Necrosis | Altered Intercellular Communication | The high motility group box 1 (HMGB1) protein triggers inflammation, cell proliferation and cell survival through its receptor for advanced glycation end products (RAGE) upon release from stressed or necrotic cells. | 25772690 |
| Inflammation, Fibrosis Assessment, Biatrial enlargement, Necrosis | Altered Intercellular Communication | In parallel with AF, KO mice developed progressive biatrial enlargement with inflammation, heterogeneous fibrosis, and loss of cardiomyocyte population with apoptosis and necrosis. | 25773299 |
| Inflammation, Necrosis | Altered Intercellular Communication | Fibrocartilage exhibited reactive features including increased extracellular myxoid matrix, binucleation, and focal necrosis, without cellular inflammation. | 25774101 |
| Inflammation, Metabolic Syndrome X, Microalbuminuria, ETV3 wt Allele, Non-alcoholic Fatty Liver Disease | Altered Intercellular Communication | Odds ratios (ORs) examining the association between intermediate endpoints (metabolic syndrome [MetS], nonalcoholic fatty liver disease [NAFLD], systemic inflammation, and microalbuminuria) and the two metabolic phenotypes were evaluated. | 25774664 |
| Microalbuminuria, Inflammation, Non-alcoholic Fatty Liver Disease, ETV3 wt Allele | Altered Intercellular Communication | After multivariable adjustment, compared to the insulin-sensitive group, the insulin-resistant group had higher odds of having MetS (OR, 5.47; 95% confidence interval [CI]: 1.72, 17.35; p=0.004) and NAFLD (OR, 8.66; 95% CI, 2.48, 30.31; p=0.001), but not systemic inflammation (OR, 1.06; 95% CI: 0.56, 2.03; p=0.86) or microalbuminuria (OR, 1.71; 95% CI, 0.49, 6.04; p=0.403). | 25774664 |
| Inflammation | Altered Intercellular Communication | Moreover, CTD in patients with cardiovascular involvement was more likely to be complicated by ILD (p < 0.01), which manifested as a higher alveolar inflammation score (p < 0.05). | 25775471 |
| Inflammation | Altered Intercellular Communication | Cardiovascular involvement is increased in CTD patients, and is associated with ILD with a higher alveolar inflammation score. | 25775471 |
| Inflammation, Data types - Address | Altered Intercellular Communication | Increasing evidence implicates inflammation in AD, the origins of which are not completely understood. | 25775543 |
| Inflammation, Data types - Address | Altered Intercellular Communication | We investigated whether circulating Ab could initiate inflammation in AD via the plasma contact activation system. | 25775543 |
| Inflammation | Altered Intercellular Communication | These findings suggest that delayed vascular healing and persistent peristent inflammation may be present even at 12 months after Zilver PTX implantation. | 25775679 |
| Osteomyelitis, Inflammation, Thrombophlebitis | Altered Intercellular Communication | The inflammation process spreads from sinuses by valveless diploic veins of the skull as thrombophlebitis or by direct extension of osteomyelitis. | 25775820 |
| Inflammation, Bacterial Endocarditis | Altered Intercellular Communication | The mechanisms that underlie valvular inflammation in streptococcus-induced infective endocarditis (IE) remain unclear. | 25776751 |
| Sepsis, Inflammation, Observation Method - Coagulation | Altered Intercellular Communication | Inflammation and coagulation are closely interrelated processes in the pathogenesis of sepsis. | 25776897 |
| Inflammation, Diverticulosis | Altered Intercellular Communication | It remains unclear whether diverticulosis, absent inflammation, is responsible for chronic bowel symptoms. | 25777157 |
| Inflammation, Neoplasms | Altered Intercellular Communication | An increased peripheral blood neutrophil to lymphocyte ratio (NLR) is a marker of systemic inflammation and is linked to poor prognosis in some solid tumors. | 25777682 |
| Inflammation, Bronchiolitis Obliterans, Fibrosis Assessment, Lung Diseases, Obstructive | Altered Intercellular Communication | Bronchiolitis obliterans (BO) was defined as a nonreversible obstructive lung disease in which the bronchioles are always compressed and narrowed by fibrosis or inflammation. | 25777978 |
| Inflammation | Altered Intercellular Communication | Tartrate-resistant acid phosphatase 5a (TRACP5a) is proposed to be related to chronic inflammation. | 25778334 |
| Refractory anemias, Inflammation, ciliary vesicle | Altered Intercellular Communication | Since inflammation and Endothelial Progenitor Cells (EPCs) imbalance have been reported in RA patients to be related to CV disease, we wondered whether RDW could be linked to endothelial repair failure in RA. | 25778627 |
| Pain Distress Question, Inflammation, Exudate, Edema, Bipolar Disorder, Fatigue | Altered Intercellular Communication | The EFA identified two distinct symptom clusters: a 'systemic symptom cluster' consisting of pain, fatigue and depressive symptoms; and a 'localised-leg symptom cluster' including pain, fatigue, oedema, lower limb inflammation and exudate. | 25779851 |
| Inflammation | Altered Intercellular Communication | Abrogation of mesenchymal TGFb signalling markedly attenuated bleomycin-induced fibrotic pathology, which was independent of altered early inflammation. | 25779936 |
| Chronic Periodontitis, Inflammation | Altered Intercellular Communication | Chronic periodontal diseases involve bacteria-induced inflammation of the tissues supporting the teeth. | 25780017 |
| Inflammation, Hypertension, CTCAE, Dental Plaque | Altered Intercellular Communication | Hypertension was also associated with high level of dental plaque [OR = 1.90, 95% CI = 1.55-2.33], dental calculus [OR = 1.18, 95% CI = 1.07-1.29] and gingival inflammation [OR = 1.56, 95% CI = 1.35-1.80] Moreover, in this subset <65 years, the risk of hypertension increases with the number of dental exposure. | 25780017 |
| Inflammation, Hypertension, CTCAE | Altered Intercellular Communication | The present study indicates that insufficient masticatory function, poor oral hygiene, and oral inflammation are associated with hypertension in subject <65. | 25780017 |
| Inflammation, Crohn Disease | Altered Intercellular Communication | Fecal calprotectin (fCal) is widely used as marker of gut inflammation and is strongly associated with the severity of endoscopic lesions in Crohn's disease (CD). | 25781366 |
| Increased insulin level, Endocrine System Diseases, Hypothyroidism, Diabetes Mellitus | Altered Intercellular Communication | They may be associated with endocrine disorders, including hypothyroidism, diabetes mellitus, hyperinsulinemia and growth hormone (GH) deficiency. | 25781523 |
| Narrow Band Imaging, Granulomatosis, Autoimmune Diseases, Granulomatosis with polyangiitis, vascular inflammations, Systemic Vasculitis | Altered Intercellular Communication | Because granulomatosis with polyangiitis (GPA) (Wegener granulomatosis) is an autoimmune disease defined by vascular inflammation, we examined patients with GPA and with NBI to evaluate whether disease-specific mucosal vascular patterns were present. | 25781561 |
| Inflammation, Coronary heart disease, Choline Dehydrogenase, Mitochondrial | Altered Intercellular Communication | Variants at the interleukin 6 receptor (IL6R) gene regulate inflammation and are associated with risk of coronary heart disease (CHD). | 25781951 |
| ARCN1 gene, Inflammation, Chronic Obstructive Airway Disease | Altered Intercellular Communication | Amplified inflammation persists in the airways of patients with chronic obstructive pulmonary disease (COPD); however, the underlying mechanism is still unclear. | 25782336 |
| Abnormal inflammatory response | Altered Intercellular Communication | Th17/T regulatory cells (Treg) imbalance may exist in the airways and contribute to this abnormal inflammation. | 25782336 |
| Neurodegenerative Disorders, Inflammation | Altered Intercellular Communication | Inflammation in the aging brain increases risk for neurodegenerative disease. | 25784210 |
| Herpes Simplex Infections, Inflammation, primary infection nos, Traumatic injury | Altered Intercellular Communication | Herpes simplex virus (HSV) primary infection and reactivation has been associated with the inflammation and transient decrease in immunocompetence after surgery and local trauma. | 25785383 |
| Inflammation | Altered Intercellular Communication | To further improve the clinical signs and symptoms and decrease chronic inflammation, rebamipide was added to diquafosol. | 25785527 |
| Inflammation, Metaplasia, Squamous metaplasia | Altered Intercellular Communication | Nasal cytology analysis demonstrated a higher percentage of neutrophilic inflammation and squamous cell metaplasia and mucous cell metaplasia in treated patients (p < 0.05). | 25785741 |
| Crohn Disease, Inflammation | Altered Intercellular Communication | Crohn's disease-related inflammation is characterized by reduced activity of the immunosuppressive cytokine transforming growth factor b1 (TGF-b1) due to high levels of SMAD7, an inhibitor of TGF-b1 signaling. | 25785968 |
| Malignant Neoplasms, Colitis | Altered Intercellular Communication | Elective colonoscopy was considered in cases in which typical colonic wall thickening was observed on CT, suggesting colonic inflammation or malignancy (239 patients; 27%). | 25786443 |
| Histiocytosis, Langerhans-Cell, Inflammation | Altered Intercellular Communication | Rather than coincidence, we hypothesize that agminated flexural melanocytic nevi are a late sequela of LCH, possibly resulting from immune tolerance or a reaction to local inflammation. | 25787131 |
| vascular inflammations, Dental Plaque | Altered Intercellular Communication | Placental growth factor (PlGF) contributes to atherogenesis through vascular inflammation and plaque destabilization. | 25788536 |
| Inflammatory abnormality of the eye | Altered Intercellular Communication | Inclusion criteria were positive syphilis serology, ocular inflammation on clinical examination and appropriate syphilis treatment. | 25788666 |
| Inflammation, HIV Coinfection | Altered Intercellular Communication | Rates of HIV coinfection were high, with patients exhibiting both anterior and posterior segment inflammation. | 25788666 |
| allergic inflammation, Gastrointestinal Diseases | Altered Intercellular Communication | Eosinophilic disorders of the gastrointestinal tract are an emerging subset of immune pathologies within the spectrum of allergic inflammation. | 25789989 |
| Sjogrens Syndrome", GYPB gene, Autoimmune Diseases | Altered Intercellular Communication | Sjogren's syndrome (SS) is a rheumatic autoimmune disease characterized by inflammation of exocrine glands. | 25790192 |
| Sepsis, Inflammation | Altered Intercellular Communication | Clinical manifestations of sepsis are not caused directly by the invading pathogens, but rather mostly by systemic inflammation that leads to activation of the coagulation system. | 25790536 |
| Inflammation, Bacterial Infections | Altered Intercellular Communication | The occurrence of a bacterial infection during anti-viral treatment was defined as the onset of local or systemic inflammation as a result of pathogenic bacteria. | 25790806 |
| Macular Edema, Cystoid, Inflammation | Altered Intercellular Communication | Intravitreal dexamethasone implant for cystoid macular edema and inflammation after scleral buckling. | 25790811 |
| Irvine-Gass Syndrome, Inflammation | Altered Intercellular Communication | Inflammation may be the major causative factor in the development of postoperative cystoid macular edema. | 25790811 |
| Retinal Detachment, Macular Edema, Cystoid, Choroiditis | Altered Intercellular Communication | A 59-year-old phakic woman treated with scleral buckling for macula-off retinal detachment presented 2 months after surgery with cystoid macular edema with choroidal inflammation. | 25790811 |
| Macular Edema, Cystoid, Choroiditis, Edema | Altered Intercellular Communication | Cystoid macular edema and choroidal inflammation are difficult to treat, but the improvement observed in this case of post scleral buckling macular edema and choroidal inflammation showed how a dexamethasone implant proved to be useful during the 6-month follow-up. | 25790811 |
| Inflammation | Altered Intercellular Communication | Response of biomarkers of inflammation and coagulation to short-term changes in central site, local, and predicted particle number concentrations. | 25791025 |
| Inflammation | Altered Intercellular Communication | Only central site PNC increased blood markers of inflammation while near-highway and predicted residential values did not. | 25791025 |
| Inflammation, Exacerbation | Altered Intercellular Communication | These data together suggest a potential role for this MAPK in Th2 inflammation and possibly during COPD exacerbations. | 25791156 |
| Inflammation, Alkalosis | Altered Intercellular Communication | The use of CD is safe and effective in OL-HDF, and it improves dialysis efficacy, postdialysis alkalosis, and inflammation. | 25791278 |
| Hepatitis | Altered Intercellular Communication | Invariant natural killer T cell deficiency leads to the development of spontaneous liver inflammation dependent on gdT cells in mice. | 25791517 |
| Hepatitis | Altered Intercellular Communication | We measured liver inflammation and the cytokine profiles of liver mononuclear cells in BALB/c wild-type (WT) mice and BALB/c Ja18-deficient (KO) mice lacking iNKT cells. | 25791517 |
| Hepatitis | Altered Intercellular Communication | Spontaneous liver inflammation, hepatocyte damage, and anti-nuclear-antibody production occurred in Ja18 KO mice but not in WT mice. | 25791517 |
| Hepatitis | Altered Intercellular Communication | In Ja18 KO mice, the administration of anti-gdT-cell-receptor antibody abolished liver inflammation, hepatocyte damage, and IL-17 production. | 25791517 |
| Inflammation, Autonomic nervous system disorders | Altered Intercellular Communication | Our findings suggest a joint effect of IR and inflammation on cardiac autonomic dysfunction. | 25791914 |
| APP gene, Inflammation, Aortic Aneurysm, Abdominal | Altered Intercellular Communication | The rates of growth of medically treated abdominal aortic aneurysms (AAA) are difficult to determine, and relationships with parietal inflammation and with metabolic parameters from (18)F-FDG PET remain unclear. | 25791991 |
| Gastrointestinal Diseases, Hepatitis, Neuropathy, Colitis, Hypophysitis, CTCAE, Diarrhea, Hypothyroidism, Dermatitis | Altered Intercellular Communication | These specific AEs include dermatitis, gastrointestinal disorders (diarrhea, colitis), hepatitis, hypophysitis, hypothyroidism, neuropathy, and iritis/inflammation of the ciliary body. | 25792081 |
| Respiratory Hypersensitivity, AHR wt Allele, Airway structure | Altered Intercellular Communication | There is increasing interest in the role of indirect bronchial challenges because clinical studies have shown that indirect airway hyperresponsiveness (AHR) reflects underlying airway inflammation better than direct AHR. | 25792296 |
| Airway structure | Altered Intercellular Communication | Fractional exhaled nitric oxide (FeNO) appears to be a useful clinical tool for assessing airway inflammation noninvasively. | 25792296 |
| Inflammation, Depression, CTCAE | Altered Intercellular Communication | Unhealthy lifestyle may increase later depression via inflammation in older women but not men. | 25795094 |
| Inflammation, Bipolar Disorder | Altered Intercellular Communication | The findings raise the possibility that unhealthy lifestyle and psychosocial stress may drive inflammation and subsequent depressive symptoms. | 25795094 |
| Inflammation, Atherosclerosis | Altered Intercellular Communication | The presence of proinflammatory monocytes/macrophages (CD14+CD16+) has been documented in conditions of inflammation, such as atherosclerosis. | 25795161 |
| Inflammation, Cardiovascular Diseases | Altered Intercellular Communication | C-reactive protein (CRP) is increasingly measured as a marker of systemic inflammation that predicts elevated risk for cardiovascular disease. | 25795257 |
| Inflammation, Hypercholesterolemia, Endothelial dysfunction | Altered Intercellular Communication | Cowpea protein reduces LDL-cholesterol and apolipoprotein B concentrations, but does not improve biomarkers of inflammation or endothelial dysfunction in adults with moderate hypercholesterolemia. | 25795948 |
| Inflammation, Data types - Address | Altered Intercellular Communication | Increasing evidence indicates that inflammation in the brain is a powerful factor in AD progression. | 25796175 |
| Inflammation | Altered Intercellular Communication | HF is an acute stress that triggers a state of inflammation which may affect immune responses and physical recovery. | 25797136 |
| Inflammation, Opportunistic Infections | Altered Intercellular Communication | Our data showed that the stress caused by HF negatively affects initial PMN responses shortly after the event and that may negatively influence clinical outcomes such as resolving long-term inflammation and recovery, as well as explaining susceptibility to opportunistic infections. | 25797136 |
| ARCN1 gene, Inflammation, Cardiovascular system | Altered Intercellular Communication | Evaluation of Markers of Inflammation and Oxidative Stress in COPD Patients with or without Cardiovascular Comorbidities. | 25797323 |
| ARCN1 gene, Inflammation, Cardiovascular Diseases, Cyclophosphamide/Vincristine/Dacarbazine Regimen, Chronic Obstructive Airway Disease | Altered Intercellular Communication | Although both chronic obstructive pulmonary disease (COPD) and cardiovascular diseases (CVD) are characterised by chronic, systemic inflammation, their reciprocal interactions are poorly understood. | 25797323 |
| ARCN1 gene, Inflammation | Altered Intercellular Communication | Although systemic inflammation coexists with COPD, it is not elevated in COPD patients with CVD. | 25797323 |
| Primary malignant neoplasm, Demographics Domain, Myositis, Symptoms, Abnormal pectoral muscle morphology | Altered Intercellular Communication | Also, muscle inflammation can precede the clinical muscle symptoms, and paraneoplastic DM should be considered as a possible differential diagnosis in the assessment of cancer patients who present with abnormal muscle tracer uptake in PET-CT scans. | 25797574 |
| Inflammation, Neoplasms | Altered Intercellular Communication | Tumor development and inflammation were determined by endoscopy. | 25797700 |
| Inflammation, Waldenstrom Macroglobulinemia, physiopathological | Altered Intercellular Communication | IgG4 related diseases (IgG4-RD) are characterized mainly by organic dysfunction and inflammation with lymphoplasmacytic cells infiltration. | 25797707 |
| Inflammation, Atherosclerosis | Altered Intercellular Communication | These findings may provide insight into the role of HCMV in the pathogenesis of atherosclerosis and chronic inflammation in elderly individuals. | 25797894 |
| Inflammation | Altered Intercellular Communication | Inadequate separation of vessel and nerve or adhesive inflammation surrounding the nerve root may cause recurrence. | 25798798 |
| Refractory anemias, Inflammation, Cardiovascular Diseases | Altered Intercellular Communication | This study suggests that inflammation induced by the IL-33/ST2 axis may play a significant role in the development of cardiovascular disease in RA. | 25798875 |
| Inflammation, Cushing Syndrome, Dyslipidemias | Altered Intercellular Communication | Dyslipidemia and chronic inflammation markers are correlated with telomere length shortening in Cushing's syndrome. | 25799396 |
| Inflammation | Altered Intercellular Communication | Telomere length (TL) shortening is a novel CVR marker, associated with inflammation biomarkers. | 25799396 |
| Inflammation, Hypertension, CTCAE, Obesity | Altered Intercellular Communication | TL is shortened in dyslipidemic CS patients, further worse if hypertension and/or obesity coexist and is negatively correlated with increased inflammation markers. | 25799396 |
| Inflammation | Altered Intercellular Communication | Increased lipids and a "low" grade inflammation may contribute to TL shortening and consequently to premature ageing and increased morbidity in CS. | 25799396 |
| Neurotransmitters, physiopathological | Altered Intercellular Communication | Olfactory dysfunction and neurotransmitter disturbance in olfactory bulb of transgenic mice expressing human A53T mutant a-synuclein. | 25799501 |
| Inflammation, Endothelial dysfunction | Altered Intercellular Communication | The presence of chronic inflammation in young adults with AP may cause early endothelial dysfunction documented by the reduced EFR. | 25799534 |
| Chronic Bacterial Prostatitis, Inflammation, Sexual Dysfunction | Altered Intercellular Communication | An open, prospective, comparative, randomized, placebo-controlled study on the evaluation of the efficacy and safety of combined drug prolit super in patients with chronic abacterial prostatitis without signs of inflammation (NIH 3B category), complicated by sexual dysfunction, was performed. | 25799722 |
| Chronic Bacterial Prostatitis, Inflammation, Sexual Dysfunction | Altered Intercellular Communication | The results of the study allows to recommend the appointment of prolit super.in routine clinical practice for patients with chronic abacterial prostatitis without signs of inflammation, complicated by sexual dysfunction. | 25799722 |
| Granulomatous inflammation | Altered Intercellular Communication | Out of 28 (59.57%) cases with positive yield 21 (44.68%) were found to have granulomatous inflammation and 10 (21.28%) cases were malignant. | 25799803 |
| Pituitary Gland, physiopathological, Congenital Abnormality | Altered Intercellular Communication | Most pituitary lesions are detected during the investigation of symptoms associated with hormonal dysfunction and vision abnormalities. | 25800168 |
| Pituitary Diseases, physiopathological | Altered Intercellular Communication | Hormonal dysfunction is quite prevalent, including symptomatic presentations, which suggests that there seems to be a low sensitivity for the diagnosis of pituitary disease. | 25800168 |
| Vasculitis | Altered Intercellular Communication | A significant increase of microbiological investigations, imaging techniques and blood inflammation markers were noted after consulting the ID specialist. | 25800800 |
| Inflammation, Chronic ulcer, Ulcer, Fracture, Damage | Altered Intercellular Communication | Magnetic resonance imaging, computed tomography as well as bone scintigraphy showed fractures of the right back rib adjacent to the ulcer, which was thought to be attributable to bone damage due to X-ray radiation and/or persistent secondary inflammation of the chronic ulcer. | 25800815 |
| Inflammation, Asthma, Psoriasis | Altered Intercellular Communication | Psoriasis and asthma are disorders driven by inflammation. | 25801416 |
| Inflammation, Obesity | Altered Intercellular Communication | Obesity has been associated with both changes in adipose tissue lipid metabolism and inflammation. | 25801691 |
| Autoimmune Diseases, Inflammation | Altered Intercellular Communication | Gamma-delta T lymphocytes and 25-hydroxy vitamin D levels as key factors in autoimmunity and inflammation: the case of zoledronic acid-induced acute phase reaction. | 25801887 |
| Autoimmune Diseases, Inflammation, Osteoporosis | Altered Intercellular Communication | Zoledronic acid (ZA) infusion for osteoporosis is frequently associated with the onset of an acute phase reaction (APR) secondary to the activation of gd T cell receptor (TCR) lymphocytes (gd T cells) and to low vitamin D levels, similar to what is observed in chronic inflammation and autoimmunity. | 25801887 |
| Inflammation, Miller Dieker syndrome | Altered Intercellular Communication | The present study provides genetic evidence that inflammation and immune dysregulation responses that involve the interferon signaling pathway in the BM microenvironment are associated with MDS pathogenesis, which suggests BM MSCs as a possible therapeutic target in MDS. | 25803272 |
| Localized scleroderma, Inflammation | Altered Intercellular Communication | We report a previously well 7-year-old Chinese girl presenting with early facial morphea mimicking an acquired PWS with unusual histologic features of perineural inflammation. | 25803570 |
| Localized scleroderma, Inflammation, Inflammatory | Altered Intercellular Communication | The presence of cutaneous perineural inflammation may be seen in a small percentage of cases of morphea and appears to be a feature of early inflammatory morphea. | 25803570 |
| Inflammation, Weight decreased | Altered Intercellular Communication | In vivo, however, the virulence and replicative capacity of the different HMPV strains did not appear to be solely dependent on the F gene but also on the viral background, with the strains containing the C-85473 background inducing more weight loss as well as increased lung viral titers, pro-inflammatory cytokines and inflammation than strains containing the CAN98-75 background. | 25803584 |
| Inflammation, Colorectal Carcinoma | Altered Intercellular Communication | Although it is clear that chronic inflammation is a risk factor for colorectal cancer, the details remain uncertain. | 25804623 |
| Pancreatic Trypsin Secretory Inhibitor, Kazal, Primary malignant neoplasm, Inflammation | Altered Intercellular Communication | Evidence suggests that SPINK1 is an important growth factor that connects chronic inflammation and cancer. | 25804623 |
| Grisels syndrome | Altered Intercellular Communication | Grisel's syndrome, an inflammation-mediated atlanto-axial instability occurs rarely in children after adenoidectomy. | 25805067 |
| Fibrosis Assessment, Hepatitis | Altered Intercellular Communication | The levels of SAMSN1 mRNA in noncancerous liver were not affected by background liver inflammation or fibrosis. | 25805236 |
| Myopia, Duane Retraction Syndrome, Cataract | Altered Intercellular Communication | High myopia has long been recognized as an inflammation-related disease, and high myopic eyes are thought to have a proinflammatory internal microenvironment, which might predispose to the occurrence of certain inflammation-related complications such as fibrotic capsular contraction syndrome after cataract surgery. | 25805322 |
| Aneurysmal, Inflammation, Necrosis | Altered Intercellular Communication | The aneurysmal wall following clipping showed granulomatous inflammation with necrosis, and occluded aneurysmal walls were found with collagenous fibrous tissue. | 25805535 |
| Sarcoidosis | Altered Intercellular Communication | Sarcoidosis is a multisystem chronic inflammatory condition of unknown etiology that has the potential to involve every tissue in the body. | 25805948 |
| Inflammation, Endothelial dysfunction, Atherosclerosis | Altered Intercellular Communication | We therefore sought to investigate the associations of inflammation, endothelial dysfunction and cardiovascular risk factors with platelet activation and monocyte-platelet aggregate (MPA) formation in 330 patients undergoing angioplasty with stent implantation for atherosclerotic cardiovascular disease. | 25807315 |
| Inflammation, Musculoskeletal Pain | Altered Intercellular Communication | Polymyalgia rheumatica: inflammation suppression with low dose of methylprednisolone or modified-release prednisone. | 25807425 |
| Metabolic Diseases, Urinary Calculi | Altered Intercellular Communication | [Hormonal and metabolic disorders as systemic factor for the formation of urinary calculi]. | 25807757 |
| vascular inflammations, Psoriasis | Altered Intercellular Communication | Subclinical systemic and vascular inflammation detected by (18) F-fluorodeoxyglucose positron emission tomography/computed tomography in patients with mild psoriasis. | 25807844 |
| Psoriasis, Arteritis | Altered Intercellular Communication | The association between psoriasis and arterial inflammation, however, has been noted mostly in patients with moderate to severe psoriasis. | 25807844 |
| Inflammation, Psoriasis, Cardiovascular Diseases | Altered Intercellular Communication | Therefore, it is still not clear whether mild psoriasis also increases the arterial inflammation and cardiovascular disease. | 25807844 |
| Inflammation, Psoriasis | Altered Intercellular Communication | The "candy cane sign", which represents typical arterial inflammation of the thoracic aorta, was noted upon PET in the majority of psoriasis cases. | 25807844 |
| Psoriasis, Arteritis | Altered Intercellular Communication | In conclusion, mild psoriasis is also associated with arterial and hepatic inflammation, which can be readily demonstrated by using FDG-PET/CT. | 25807844 |
| Secondary malignant neoplasm of liver | Altered Intercellular Communication | Prognostic performance of inflammation-based prognostic indices in patients with resectable colorectal liver metastases. | 25807934 |
| Nevus, Inflammation, Lichen Sclerosus et Atrophicus | Altered Intercellular Communication | Histopathologic and immunohistochemical examination performed after topical treatment, showed a compound melanocytic naevus with an underlying inflammation consistent with lichen sclerosus. | 25808039 |
| Inflammation, MS gene | Altered Intercellular Communication | Cerebrospinal fluid markers reveal intrathecal inflammation in progressive multiple sclerosis. | 25808056 |
| Inflammation, Immune System Diseases | Altered Intercellular Communication | The management of complex patients with neuroimmunological diseases is hindered by an inability to reliably measure intrathecal inflammation. | 25808056 |
| Inflammation, Immune System Diseases | Altered Intercellular Communication | The cell-specific biomarkers of intrathecal inflammation may improve diagnosis and management of neuroimmunological diseases and provide pharmacodynamic markers for future therapeutic developments in patients with intrathecal inflammation that is not captured by imaging, such as in progressive MS. | 25808056 |
| Inflammation | Altered Intercellular Communication | Such cement remnants may favor the development of inflammation in the peri-implant tissue. | 25808842 |
| Inflammation, Neoplasms | Altered Intercellular Communication | UBC with HER2 amplification presented with a broad variety of histological variants (median 2 vs. 1), frequently featured micropapillary tumor components (77 % vs. 8 %) and demonstrated a high amount of tumor associated inflammation. | 25809292 |
| Eosinophilic esophagitis, "Extra-osseous Ewings sarcoma | Altered Intercellular Communication | Eosinophilic esophagitis (EoE) is an antigen/allergy-mediated chronic inflammatory condition. | 25809945 |
| CLU protein, human, Ischemia, Inflammation, Communicable Diseases | Altered Intercellular Communication | Hemodialysis (HD) patients with critical limb ischemia (CLI) suffer chronic inflammation and repeated infection, require intervention, and may have a protracted hospital stay. | 25810351 |
| Inflammation | Altered Intercellular Communication | In HIV+ only, higher adiponectin and IL-6 were associated with worse NP test scores, supporting a role for chronic inflammation and adipocytokine imbalance in neurocognitive decline in HIV+ persons. | 25810377 |
| Sepsis, Inflammation, Critical Illness, Bacterial Infections | Altered Intercellular Communication | Strikingly, no differences in miR-223 levels were found in critically ill patients with or without sepsis, and serum levels of miR-223 did not correlate with classical markers of inflammation or bacterial infection. | 25810564 |
| Inflammation, Obesity | Altered Intercellular Communication | Associations of fibroblast growth factor-23 with markers of inflammation, insulin resistance and obesity in adults. | 25811862 |
| Inflammation, Chronic Kidney Diseases | Altered Intercellular Communication | Prior studies have shown that FGF23 concentrations are associated with markers of inflammation and insulin resistance but they have been limited by a focus on persons with chronic kidney disease (CKD) and lack of race and sex diversity. | 25811862 |
| Vascular lesions, Inflammation, Neoplasms | Altered Intercellular Communication | The sensitivity and specificity of CT extravasation and nonvascular findings for predicting vascular lesions and inflammation or tumors were 37.8 and 88.9 and 81.3 and 80.9%, respectively. | 25812518 |
| Inflammation, Neoplasms | Altered Intercellular Communication | Contrast-enhanced CT in acute LGIB settings was safe and correctly identified the presence and location of active bleeding, as well as severe inflammation or tumor stenosis, facilitating decision making. | 25812518 |
| Autoimmune Diseases, Thrombus, Antiphospholipid Antibodies | Altered Intercellular Communication | Antiphospholipid antibodies (aPL) are heterogeneous group of antibodies found in patients with autoimmune diseases and inflammatory conditions and are associated with thrombotic events. | 25812700 |
| Inflammation, Cerebral Aneurysm, Rupture | Altered Intercellular Communication | A growing body of evidence suggests that inflammation actively participates in cerebral aneurysm initiation, progression, and rupture. | 25813065 |
| Dermatitis, Atopic, Inflammation, Data types - Address, Allergy - Charge Type Reason | Altered Intercellular Communication | Atopic dermatitis (AD) is a chronic inflammation of the skin recognised to be one of the first clinical signs of allergy. | 25813073 |
| Anxiety, CTCAE 3.0, Inflammation | Altered Intercellular Communication | Recent evidence has suggested that anxiety has a genetic basis and is associated with inflammation. | 25813148 |
| Gall Bladder Diseases, Postoperative Complications, Actual blood loss, Acute inflammation, Acute Cholecystitis | Altered Intercellular Communication | These findings suggest that when compared to SILC for gallbladder diseases without acute inflammation, SILC for acute cholecystitis was associated with a longer operative time, increased blood loss, higher rate of additional trocar requirement, higher rate of postoperative complications, and longer hospital stay. | 25813307 |
| Inflammation, Acute Cholecystitis | Altered Intercellular Communication | The difficulties associated with SILC for acute cholecystitis were affected by the timing of surgery and the grade of inflammation. | 25813307 |
| Inflammatory abnormality of the eye | Altered Intercellular Communication | Systemic ATT led to significant improvement and resolution of the ocular inflammation. | 25813375 |
| Inflammation, Chronic disease, Obesity | Altered Intercellular Communication | Obesity, defined by an excess amount of body fat or a percent body fat higher than 30 % for women is a complex chronic disorder with multifactorial etiology and is accompanied by chronic low-grade inflammation, which results in elevated pro-inflammatory cytokines. | 25813986 |
| Inflammation | Altered Intercellular Communication | The presence of MSC in EMB, cardiac inflammation, and SDF-1a mRNA expression were detected via immunohistochemistry and real-time PCR. | 25814787 |
| Inflammation | Altered Intercellular Communication | There was a 29.9% (P < 0.01) transcardiac reduction of circulating MSC in patients with CMi, correlating with the extent of cardiac inflammation (P < 0.05, multivariate analysis). | 25814787 |
| Inflammation | Altered Intercellular Communication | Endogenous MSC continuously migrate to the heart in patients with CMi triggered by cardiac inflammation. | 25814787 |
| Hepatitis | Altered Intercellular Communication | The frequency of M-MDSCs, however, had no correlation with HCV RNA loads, aspartate aminotransferase (AST), alanine aminotransferase (ALT), and the level of liver inflammation degree. | 25815313 |
| Retinitis, Diabetes Mellitus | Altered Intercellular Communication | MicroRNA-146b-3p regulates retinal inflammation by suppressing adenosine deaminase-2 in diabetes. | 25815338 |
| Diabetic Retinopathy, Retinitis, GDC Disease Response Terminology | Altered Intercellular Communication | Hyperglycemia- (HG-) Amadori-glycated albumin- (AGA-) induced activation of microglia and monocytes and their adherence to retinal vascular endothelial cells contribute to retinal inflammation leading to diabetic retinopathy (DR). | 25815338 |
| Diabetes Mellitus | Altered Intercellular Communication | However, because ADA2 gene has not been identified in mouse genome, how diabetes alters adenosine-dependent anti-inflammation remains unclear. | 25815338 |
| Retinitis, Diabetes Mellitus | Altered Intercellular Communication | These results suggest a regulatory role of miR-146b-3p in diabetes related retinal inflammation by suppressing ADA2. | 25815338 |
| Inflammation, Electrocardiogram: myocardial infarction (finding), Atherosclerosis | Altered Intercellular Communication | Inflammation and genetics have key roles in the pathogenesis of atherosclerosis, and the etiology of myocardial infarction (MI). | 25815703 |
| Inflammation | Altered Intercellular Communication | Examination of the right eye showed vitreous cells, suggesting inflammation of the central retinal vein leading to a CRVO as the presumed mechanism. | 25815857 |
| Inflammation, Chronic disease | Altered Intercellular Communication | The overall burden of chronic disease, inflammation and cardiovascular risk increases with age. | 25815855 |
| Inflammation, Metabolic Syndrome X | Altered Intercellular Communication | A composite z-score for systemic inflammation increased significantly with age in subjects without metabolic syndrome (P=0.004 and P<0.006 for Caucasians and African Americans, respectively) but not in subjects with metabolic syndrome (P=0.009 for difference in age trend between metabolic syndrome and non-metabolic syndrome). | 25815855 |
| vascular inflammations | Altered Intercellular Communication | In contrast, no similar age trend was found in vascular inflammation. | 25815855 |
| Inflammation, Metabolic Syndrome X | Altered Intercellular Communication | Our results underscore that already at a young age, presence of a metabolic burden enhances inflammation to a level that appears to be similar to that of decades older people without metabolic syndrome. | 25815855 |
| Inflammation, Cardiovascular Diseases | Altered Intercellular Communication | In this study we evaluated whether annual exposure to ambient air pollution is associated with systemic inflammation, which is hypothesized to be an intermediate step to cardiovascular disease. | 25816055 |
| Inflammation, Dysbiosis | Altered Intercellular Communication | could be evaluated as a dysbiotic reaction, and the presence of opportunistic microflora against the background of high IFNg content with CI of above 10 c.u.--as a development of systemic inflammation due to translocation of dysbiotic microflora into the bloodflow. | 25816517 |
| Helicobacter pylori | Altered Intercellular Communication | Thus, in patients with H. pylori inflammation was noted mainly in the antral mucosa and dystrophic changes--in the duodenal mucosa. | 25816643 |
| Inflammation | Altered Intercellular Communication | In the presence of viruses the inflammation was expressed more in the fundal stomach and duodenum. | 25816643 |
| Hypernatremia | Altered Intercellular Communication | NT-proBNP is a cardiac neurohormone secreted from the ventricles in response to ventricular volume expansion and pressure overload and may also be elevated in the setting of reduced myocardial perfusion. | 25816778 |
| Inflammation, Atherosclerosis | Altered Intercellular Communication | Iron, inflammation and atherosclerosis risk in men vs. perimenopausal women. | 25817132 |
| Inflammation, Atherosclerosis | Altered Intercellular Communication | Iron homeostasis and inflammation in the arterial wall microenvironment warrants further investigation as a potential early target for interventions that mitigate atherosclerosis risk. | 25817132 |
| Inflammation | Altered Intercellular Communication | Activated factor X (FXa) plays a key role in the coagulation cascade, whereas accumulating evidence suggests that it also contributes to the pathophysiology of chronic inflammation on the vasculature. | 25817329 |
| Communicable Diseases, Inflammation, Dryness of eye | Altered Intercellular Communication | In conclusion, changes in TLR expression occur in dry eye and could have an important role in ocular surface susceptibility to inflammation and infection. | 25817729 |
| Inflammation, Neoplasms | Altered Intercellular Communication | Systemic inflammation and immune response play a crucial role in tumor growth, and the neutrophil to lymphocyte ratio (NLR) may be a simple way to assess the host inflammatory response. | 25818659 |
| Inflammation, Rheumatic Heart Disease | Altered Intercellular Communication | The pathogenesis of LA calcification in patients with rheumatic heart disease is unknown; however, possible mechanisms include chronic strain force in the atrial wall and inflammation. | 25819539 |
| Asthma | Altered Intercellular Communication | Inflammatory phenotype classification using induced sputum appears attractive as it can be applied to inflammation-based management of the patients with asthma. | 25821354 |
| Inflammation | Altered Intercellular Communication | Our findings indicate that oxidative stress is a potential therapeutic target, as it promotes inflammation by ROS/RNS-linked pathogenesis. | 25821554 |
| Inflammation, Hand | Altered Intercellular Communication | HIV-induced systemic and localized inflammation is considered to be one of the mechanisms of HAND. | 25821806 |
| Addison Disease, Hypogonadism | Altered Intercellular Communication | Hormonal profiling variously showed a normal gonadotrope-testicular axis, gonadotropin deficiency, or primary testicular insufficiency. | 25822101 |
| Granulomatosis, Inflammation, Systemic Vasculitis | Altered Intercellular Communication | In particular, differential diagnosis from secondary chronic inflammation including granulomatosis with polyangiitis (GPA) is difficult in some cases. | 25822111 |
| Airway structure | Altered Intercellular Communication | Hs-CRP may be useful in monitoring airway inflammation resolution and improvement of health status during AECOPD treatment. | 25822151 |
| Airway structure, Inflammation, Fibrosis Assessment, Bronchiectasis | Altered Intercellular Communication | Non-cystic fibrosis (CF) bronchiectasis is characterised by chronic airway infection and neutrophilic inflammation, which we hypothesised would be associated with Th17 pathway activation. | 25822228 |
| Renal Insufficiency, Inflammation, Hypoxia, Heart failure | Altered Intercellular Communication | We hypothesized that the frequency of GT(n) repeats in pediatric heart failure (HF) reflects plasma biomarkers of different disease processes: the soluble receptor for advance glycation end products (sRAGE, marking cellular activation), oxLDL (oxidative stress), NGAL (impaired renal function), HIF-1a (hypoxia) and hsCRP (inflammation). | 25822459 |
| Inflammation, Pain Distress Question | Altered Intercellular Communication | The participants had radiographic confirmation of clinical OA of the knee, clinical signs of localized inflammation in the knee, and knee pain during walking (score >4 on a scale of 0 to 10). | 25822572 |
| Inflammation, Primary malignant neoplasm, Malignant neoplasm of stomach | Altered Intercellular Communication | This retrospective study examines the association of preneoplastic conditions and inflammation of the gastric mucosa with GOJ cancer at different locations and compares them with nonjunctional gastric cancers. | 25822856 |
| Intestinal metaplasia, Inflammation, Stomach Carcinoma, Gland | Altered Intercellular Communication | A total of 520 patients with junctional and nonjunctional gastric cancer were assessed for the presence and degree of intestinal metaplasia, glandular atrophy and inflammation in the stomach. | 25822856 |
| Intestinal metaplasia, Gastritis | Altered Intercellular Communication | Gastric inflammation and preneoplastic conditions were scored according to the updated Sydney classification and further stratified into respective operative link on gastritis assessment (OLGA) and operative link on gastritis assessment on intestinal metaplasia (OLGIM) stages. | 25822856 |
| Meningitis | Altered Intercellular Communication | It has been suggested that this may be due to the effects of pathology outside the brain parenchyma, in particular meningeal inflammation or through cerebrospinal fluid mediated factors. | 25823475 |
| Gingivitis | Altered Intercellular Communication | Among the 100 subjects, only 39% correctly identified that hormonal changes contribute to pregnancy gingivitis. | 25823479 |
| Inflammation | Altered Intercellular Communication | Some literatures supported that genes involved in both oxidative stress and prostaglandin metabolism play an important role in the process of inflammation. | 25823564 |
| Inflammation | Altered Intercellular Communication | Here we perform a study of the inflammatory response following injury in Xenopus larvae, which are able to achieve scarless wound healing and to regenerate appendages, as a preamble into understanding the role that inflammation plays during tissue repair and regeneration in this organism. | 25823652 |
| Communicable Diseases, Inflammation, Traumatic injury | Altered Intercellular Communication | Using this approach we found that the inflammatory response following injury and infection in Xenopus larvae is very similar to that seen in humans, suggesting that this model provides an easily tractable and medically relevant system to investigate inflammation following injury and infection in vivo. | 25823652 |
| Biliary Atresia, Inflammation, Fibrosis Assessment, Cholestasis | Altered Intercellular Communication | Liver histology: CMV IgM+ve biliary atresia was characterised by a greater degree of inflammation (P < 0.0001) and fibrosis (P = 0.02), whereas CMV IgM-ve isolated biliary atresia had a higher degree of lobular cholestasis (P = 0.001). | 25824438 |
| Degenerative polyarthritis, Inflammation, Synovitis | Altered Intercellular Communication | Cadherin-11 expression in OA synoviums and its correlation with synovitis score and systemic inflammation markers were explored. | 25824718 |
| Inflammation, Primary malignant neoplasm, Squamous cell carcinoma of esophagus | Altered Intercellular Communication | Preoperative LMR better predicts cancer survival compared with the cellular components of systemic inflammation in patients with ESCC undergoing esophagectomy. | 25824745 |
| Inflammation | Altered Intercellular Communication | Regarding pathogenesis, it is thought that disruption of kinetics through T lymphocyte-mediated development of chronic inflammation may be involved. | 25824754 |
| Inflammation | Altered Intercellular Communication | Although the Extracellular Matrix Metalloproteinase Inducer (EMMPRIN) regulates important processes for inflammation such as MMP-release, its expression and regulation on monocyte subsets has not been characterized. | 25824988 |
| Ischemia, Inflammation, Necrosis | Altered Intercellular Communication | We suppose that the early complications that often occur in such cases might result from a nonspecific, inflammatory reaction induced by acute tissue ischemia and necrosis, and the late local complications that occur years later may relate more to chronic inflammation, due to nonvascularized tissue, than to immunologic rejection. | 25825423 |
| Inflammation, Sleep Apnea, Obstructive, Osage language | Altered Intercellular Communication | Inflammation plays a critical role in the development and progression of obstructive sleep apnea (OSA). | 25825846 |
| Neoplasms | Altered Intercellular Communication | Expression profiling of a panel of 184 inflammation-related genes was performed in 15 chemoresistant and 19 chemosensitive HGSC tumours using the NanoString nCounter platform. | 25826225 |
| Periodontitis, Bacterial Infections | Altered Intercellular Communication | Periodontitis represents a chronic bacterial infection that induces immuno-inflammatory conditions affecting gingiva and tooth-supporting tissues. | 25826490 |
| Tumor necrosis, Carcinogenesis, Inflammation, Neoplasms | Altered Intercellular Communication | The tumor necrosis factor alpha (TNF-a) represents an important inflammation mediator associated to carcinogenesis and even to tumor progression. | 25826493 |
| Inflammation | Altered Intercellular Communication | Inflammation was determined by the local microbial flora enhanced by the action of prosthetic appliances or by the prolonged edentulous state. | 25826498 |
| Inflammation | Altered Intercellular Communication | Gingival inflammation is highly prevalent among adult populations in all regions of the world. | 25826499 |
| Inflammation, Periodontal Diseases | Altered Intercellular Communication | The methods for assessing the gingival inflammation and periodontal disease would need more precision and less user-dependence. | 25826499 |
| Degenerative polyarthritis, Inflammation | Altered Intercellular Communication | Synovial inflammation in patients with different stages of knee osteoarthritis. | 25826502 |
| Degenerative polyarthritis, Inflammation | Altered Intercellular Communication | The overexpression of mediators of inflammation and the increased mononuclear cell infiltration were seen in early OA, compared with late OA. | 25826502 |
| Inflammation | Altered Intercellular Communication | Topographic associations and density of inflammatory elements analyzed in relation with neoforming vessels suggest their implication in reparatory angiogenesis characteristic to chronic inflammation. | 25826509 |
| Pericardial Effusion, CTCAE, Acute inflammation | Altered Intercellular Communication | Cardiac Magnetic Resonance (CMR) allows evaluation of the functional and flow changes in pericardial constriction as well as detection of acute pericardial inflammation, fusion and thickening of pericardial layers and pericardial effusion. | 25827067 |
| Pericarditis, CTCAE, Acute inflammation, Pericarditis, Constrictive | Altered Intercellular Communication | The diagnosis of CP was confirmed in 53 patients while 12 patients presented signs of predominant pericardial active inflammation suggesting a diagnosis of transient constrictive pericarditis and five presented effusive-constrictive pericarditis. | 25827067 |
| Inflammation, Chronic pericarditis | Altered Intercellular Communication | A multiparametric CMR approach allowed to distinguish between active inflammation, chronic pericarditis with constriction and effusion without inflammation. | 25827067 |
| Inflammation, Ulcerative Colitis | Altered Intercellular Communication | (i) Endoscopically normal appearing colonic mucosa of patients with UC-IR remains abnormal: CLE demonstrates impaired crypt regeneration, persistent inflammation, distinct abnormalities in angioarchitecture and increased vascular permeability; molecular imaging showed increased COX2 and mtDNA mutations; (ii) CLE may serve as a new gold standard for the assessment of mucosal healing in UC. | 25827810 |
| Degenerative polyarthritis, Inflammation, Rheumatoid Arthritis | Altered Intercellular Communication | Comparative immunohistochemical evaluation of the zonal distribution of extracellular matrix and inflammation markers in human meniscus in osteoarthritis and rheumatoid arthritis. | 25827912 |
| Degenerative polyarthritis, Inflammation, Rheumatoid Arthritis | Altered Intercellular Communication | The distribution patterns of the extracellular matrix components as well as the CD44-positive cells and the inflammation markers in the peripheral zone resembled the distribution in synovial tissue, indicating that both synovia and meniscus were involved in pathological changes in osteoarthritis and rheumatoid arthritis. | 25827912 |
| Degenerative polyarthritis, Rheumatoid Arthritis, Inflammation, Arthropathy | Altered Intercellular Communication | the distribution of extracellular glycoconjugates and of cells modulating their synthesis showed similar results in both arthropathies, not enabling a differentiation between rheumatoid arthritis and osteoarthritis but underlining the role of these markers in inflammation and degradation in human meniscus. | 25827912 |
| Inflammation, Schizophrenia | Altered Intercellular Communication | Inflammation appears to play significant role in schizophrenia. | 25827958 |
| Inflammation, Chronic Obstructive Airway Disease, Smooth muscle (tissue), Abnormality of mitochondrial metabolism | Altered Intercellular Communication | Oxidative stress-induced mitochondrial dysfunction drives inflammation and airway smooth muscle remodeling in patients with chronic obstructive pulmonary disease. | 25828268 |
| ARCN1 gene, Inflammation, Chronic Obstructive Airway Disease | Altered Intercellular Communication | Inflammation and oxidative stress play critical roles in patients with chronic obstructive pulmonary disease (COPD). | 25828268 |
| Respiratory Hypersensitivity, Pneumonitis | Altered Intercellular Communication | Mice were exposed to ozone, and lung inflammation, airway hyperresponsiveness (AHR), and mitochondrial function were determined. | 25828268 |
| AHR wt Allele, Pneumonitis, Abnormality of mitochondrial metabolism | Altered Intercellular Communication | Mice exposed to ozone, a source of oxidative stress, had lung inflammation and AHR associated with mitochondrial dysfunction and reflected by decreased mitochondrial membrane potential (DPsm), increased mitochondrial oxidative stress, and reduced mitochondrial complex I, III, and V expression. | 25828268 |
| Inflammation, AHR wt Allele, Abnormality of mitochondrial metabolism | Altered Intercellular Communication | Reversal of mitochondrial dysfunction by the mitochondria-targeted antioxidant MitoQ reduced inflammation and AHR. | 25828268 |
| ARCN1 gene, Inflammation, Abnormality of mitochondrial metabolism | Altered Intercellular Communication | Mitochondrial dysfunction in patients with COPD is associated with excessive mitochondrial ROS levels, which contribute to enhanced inflammation and cell hyperproliferation. | 25828268 |
| Hypophysitis, CTCAE, Inflammation | Altered Intercellular Communication | Hypophysitis is a rare chronic inflammation of the pituitary gland corresponding currently to six histopathological subtypes. | 25828777 |
| Inflammation, Benign prostatic hypertrophy | Altered Intercellular Communication | Prostate Biopsy Markers of Inflammation are Associated with Risk of Clinical Progression of Benign Prostatic Hyperplasia: Findings from the MTOPS Study. | 25828974 |
| Inflammation, Benign prostatic hypertrophy | Altered Intercellular Communication | We measured inflammatory markers from prostate biopsies to study if inflammation is related to clinical progression of benign prostatic hyperplasia. | 25828974 |
| Inflammation, Benign prostatic hypertrophy | Altered Intercellular Communication | Inflammation as measured by CD45, CD4 and CD68 increased the risk of clinical progression of benign prostatic hyperplasia. | 25828974 |
| Inflammation | Altered Intercellular Communication | CD4 showed the highest risk where men in the highest tertile of moderate/severe inflammation were at twice the risk of progression compared to men in the lower 2 tertiles combined (HR 2.03, p=0.001). | 25828974 |
| Inflammation, Incontinence | Altered Intercellular Communication | Inflammation was more strongly associated with progression defined by acute urinary retention or incontinence (HR ranging from 2.39 [CD8, p=0.03] to 3.08 [CD4, p=0.01]) than an AUA symptom score increase (CD4, HR 1.86, p=0.01). | 25828974 |
| Inflammation | Altered Intercellular Communication | Although our data show that inflammation increases the risk of progression, our findings suggest that inflammation has a greater role in men who have conditions requiring anti-inflammatory medications. | 25828974 |
| Inflammation, Anemia | Altered Intercellular Communication | Baseline anemia prevalence was 51% with 15% prevalence of concurrent anemia and inflammation. | 25828994 |
| Inflammation, Anemia, Failure (biologic function) | Altered Intercellular Communication | In analysis of clinical failure, multivariate-adjusted hazard ratios were 6.41 (95% confidence interval [CI], 2.82-14.57) for concurrent anemia and inflammation, 0.77 (95% CI, .37-1.58) for anemia without inflammation, and 0.45 (95% CI, .11-1.80) for inflammation without anemia compared to those without anemia and inflammation. | 25828994 |
| Inflammation, Anemia | Altered Intercellular Communication | ART-naive, HIV-infected individuals with concurrent anemia and inflammation are at particularly high risk of failing treatment, and understanding the pathogenesis could lead to new interventions. | 25828994 |
| Inflammation, Anemia, HIV Infections | Altered Intercellular Communication | Reducing inflammation and anemia will likely improve HIV disease outcomes. | 25828994 |
| Inflammation, Opportunistic Infections, Anemia | Altered Intercellular Communication | Alternatively, concurrent anemia and inflammation could represent individuals with occult opportunistic infections in need of additional screening. | 25828994 |
| Airway structure, Signs and Symptoms, Respiratory | Altered Intercellular Communication | Respiratory symptoms and airway inflammation positively correlated to UFP content in EBC of symptomatic children. | 25830607 |
| Cardiovascular morbidity, Chronic Kidney Diseases | Altered Intercellular Communication | The risk for cardiovascular morbidity and mortality is increased in chronic kidney disease; in this process micro-inflammation plays an essential role. | 25830914 |
| Ulcer, Inflammation, Necrosis | Altered Intercellular Communication | In addition, bronchoscopy showed ulcers in the trachea, and histopathology disclosed findings of necrosis and inflammation of the subepithelial tissue of the trachea. | 25832936 |
| Inflammation, Crohn Disease | Altered Intercellular Communication | Recent studies suggest that markers of mesenteric inflammation, such as increased adipose tissue, may be associated with poor outcomes in Crohn's disease (CD). | 25833139 |
| Inflammation, Hypertriglyceridemia | Altered Intercellular Communication | Hypertriglyceridemia, low HDL cholesterol and DM may be good markers of local and systemic inflammation as seen in CD. | 25833139 |
| PROS1 gene, Inflammation, Calcium pyrophosphate deposition disease, Degenerative polyarthritis, Arthritis, Psoriatic | Altered Intercellular Communication | According to recent hypothesis, the inflammation has a pivotal role in the onset and progression of erosive hand osteoarthritis (EHOA), psoriatic arthritis (PsA) and chondrocalcinosis (CC)/pseudogout. | 25833145 |
| Inflammation, Fibrosis Assessment, Neoplasms | Altered Intercellular Communication | Response assessment after stereotactic ablative body radiotherapy (SABR) in lung can be confounded by radiation-induced inflammation, fibrosis and subsequent alteration of tumour motion. | 25833329 |
| Inflammation | Altered Intercellular Communication | A proinflammatory diet is associated with systemic inflammation and reduced kidney function in elderly adults. | 25833776 |
| Inflammation | Altered Intercellular Communication | We tested whether the Adapted Dietary Inflammatory Index (ADII) is associated with kidney function and whether effects of diet on chronic low-grade inflammation explain this association. | 25833776 |
| Inflammation | Altered Intercellular Communication | A proinflammatory diet was associated with systemic inflammation as well as with reduced kidney function in a combined analysis of 2 community-based cohorts of elderly individuals. | 25833776 |
| Sepsis, Inflammation | Altered Intercellular Communication | Low zinc and selenium concentrations in sepsis are associated with oxidative damage and inflammation. | 25833826 |
| Sepsis, Inflammation | Altered Intercellular Communication | Oxidative stress with dysregulated inflammation are hallmarks of sepsis. | 25833826 |
| Sepsis, Inflammation, Critical Illness | Altered Intercellular Communication | Zinc, selenium, and a series of biomarkers of oxidative stress and inflammation were measured in plasma from critically ill patients with and without sepsis. | 25833826 |
| Inflammation, Fibrosis Assessment | Altered Intercellular Communication | Peritoneal inflammation and fibrosis are responses to the uremic milieu and exposure to hyperosmolar dialysis fluids in patients on peritoneal dialysis. | 25834072 |
| Degenerative polyarthritis, Inflammation | Altered Intercellular Communication | Ultrasound-detected inflammation predicts radiographic progression in hand osteoarthritis after 5 years. | 25834142 |
| Inflammation, Swelling | Altered Intercellular Communication | Significant associations were also observed between ultrasound inflammation and progression of all individual radiographic features, and between clinical soft tissue swelling at baseline and radiographic progression. | 25834142 |
| Inflammation, Weight decreased | Altered Intercellular Communication | Factors associated with greater reductions in BMI over time and a greater risk of weight loss were higher inflammatory markers, smoking, older age, higher BMI, and less subsequent improvement in inflammation. | 25834210 |
| Inflammation | Altered Intercellular Communication | Four days subsequent to the procedure, the patient showed a systemic inflammation response syndrome. | 25834343 |
| Inflammation, Carcinogenesis, Colorectal Carcinoma | Altered Intercellular Communication | Inflammation is known to contribute to carcinogenesis in human colorectal cancer. | 25834404 |
| Inflammation, Arthritis, Lupus Erythematosus, Systemic | Altered Intercellular Communication | Association between mean platelet volume levels and inflammation in SLE patients presented with arthritis. | 25834502 |
| Meibomian Cyst, Inflammation | Altered Intercellular Communication | Histopathological diagnoses were chalazion and inflammation with mixed cells, respectively. | 25834990 |
| Inflammation, Illness (finding) | Altered Intercellular Communication | Inflammation associated with any acute illness can lead to poor appetite and low food intake in older people. | 25835231 |
| Uveitis | Altered Intercellular Communication | Association between Smoking and Uveitis: Results from the Pacific Ocular Inflammation Study. | 25835263 |
| Inflammation | Altered Intercellular Communication | In AS, inflammation upregulates the expression of BMPs in PBMCs which may lead to the radiographic progression with new bone formation. | 25835314 |
| Inflammation, Depression, CTCAE, Cardiovascular system | Altered Intercellular Communication | This study investigated whether inflammation may explain the relationship between depression and incident cardiovascular hospitalisations. | 25835436 |
| Inflammation, ovarian neoplasm | Altered Intercellular Communication | One of the proposed mechanisms behind these associations is systemic inflammation, which has also been implicated in ovarian cancer etiology. | 25837263 |
| Inflammatory Bowel Diseases, Inflammation | Altered Intercellular Communication | The increase in the concentration level of calprotectin in serum (ICP) in patients with inflammatory bowel disease (IBD) is closely associated with increased rates of acute phase of inflammation and combined with worsening of clinical and endoscopic disease activity. | 25842402 |
| Inflammation, Ulcerative Colitis | Altered Intercellular Communication | Application of the method guarantees complete excision of the rectal stump mucosa, what excludes the risk of the stump inflammation occurrence, as a sign of residual ulcer colitis in immediate and late postoperative period. | 25842878 |
| Inflammation | Altered Intercellular Communication | Contribution of microbial sensibilization and latent inflammation in the development and destabilization of atherogenesis-associated diseases seems evident. | 25842957 |
| Inflammation, Coronary Arteriosclerosis | Altered Intercellular Communication | Adventitial VV initiates the development of coronary artery diseases as an outside-in supply route of inflammation. | 25843557 |
| Inflammation, Vasculitis, CTCAE | Altered Intercellular Communication | Neuropathological findings include frank vasculitis and/or perivascular inflammation with mononuclear or multinucleated giant cells that are associated with amyloid-beta (Ab)-laden vessels. | 25846442 |
| Inflammation, Liver carcinoma, Liver Cirrhosis, FAM126A gene | Altered Intercellular Communication | Hepatocellular carcinoma (HCC) tends to develop in the liver when there is a high level of background inflammation (cirrhosis). | 25847009 |
| Inflammation, Neoplasms | Altered Intercellular Communication | Connective tissue growth factor (CTGF) is a matricellular protein involved in inflammation, tumour growth and angiogenesis. | 25847009 |
| Steatohepatitis, Hepatitis | Altered Intercellular Communication | Age-related sensitivity to endotoxin-induced liver inflammation: Implication of inflammasome/IL-1b for steatohepatitis. | 25847140 |
| Hepatitis | Altered Intercellular Communication | We also observed severe liver inflammation in aged rats as indicated by increased ALT levels in serum and increased Kupffer cells in the liver. | 25847140 |
| Overactive, Hepatitis | Altered Intercellular Communication | In summary, we demonstrated that LPS-induced liver inflammation and lipid accumulation were associated with a chronically overactive inflammasome/IL-1b pathway in aged rat livers. | 25847140 |
| Inflammation, Metaplasia, Adenocarcinoma Of Esophagus | Altered Intercellular Communication | Ductal metaplasia in oesophageal submucosal glands is associated with inflammation and oesophageal adenocarcinoma. | 25847432 |
| prostatitis | Altered Intercellular Communication | Prostatic inflammation is widespread in the male population. | 25847892 |
| prostatitis | Altered Intercellular Communication | Two groups of 50 patients each with symptoms of prostatic inflammation and ecocolorDoppler indicative of prostatitis were identified. | 25847892 |
| Inflammation, Chronic Obstructive Airway Disease | Altered Intercellular Communication | Home-based pulmonary rehabilitation improves clinical features and systemic inflammation in chronic obstructive pulmonary disease patients. | 25848241 |
| ARCN1 gene, Inflammation | Altered Intercellular Communication | COPD is characterized by pulmonary and systemic inflammation. | 25848241 |
| Inflammation, Diffuse alveolar hemorrhage, Interstitial Fibrosis Assessment | Altered Intercellular Communication | Serial imaging revealed progressive interstitial fibrosis secondary to recurrent alveolar hemorrhage and inflammation from crack cocaine. | 25848717 |
| Inflammation, Lower gastrointestinal hemorrhage, Endothelial dysfunction | Altered Intercellular Communication | We also evaluated to which extent these associations could be explained by low-grade inflammation (LGI) or endothelial dysfunction (ED). | 25848912 |
| Inflammation | Altered Intercellular Communication | Lung function, symptoms and inflammation during exacerbations of non-cystic fibrosis bronchiectasis: a prospective observational cohort study. | 25849856 |
| Inflammation, Clonal Anergy | Altered Intercellular Communication | Recent studies have initiated a paradigm shift to comprehend the immunological interactions of Wolbachia and its antigens in inflammation, apoptosis, lymphocyte anergy, etc. | 25849993 |
| Chronic dacryocystitis, Suppurative inflammation, Congenital lacrimal fistula | Altered Intercellular Communication | Therefore, we present an 8-week-old child, suffering recurrent purulent inflammation due to an amniotocele (1), a 5-year-old child having a congenital lacrimal fistula (2) and another 5-year-old child with a severe chronic dacryocystitis of both eyes after several lacrimal duct surgeries showing remaining intrasaccal silicone tubes (3). | 25851053 |
| Inflammation, Fibrosis Assessment | Altered Intercellular Communication | Biopsy specimens were scored for histological fibrosis and inflammation. | 25851300 |
| Inflammation, Fibrosis Assessment | Altered Intercellular Communication | For VTQ, both histological fibrosis (P < 0.0001) and inflammation (P = 0.04) scores were significant predictors of shear wave speed (model adjusted R (2) = 0.49). | 25851300 |
| Inflammation, Diverticulitis | Altered Intercellular Communication | Complicated cecal diverticulitis is managed surgically and the type of resection depends mainly on the extent of inflammation. | 25851946 |
| Inflammation, Complications of Diabetes Mellitus | Altered Intercellular Communication | Inflammation is regarded as one of the main reasons for the progression of diabetes complications. | 25853704 |
| Inflammation, Diabetic Retinopathy, Kidney Diseases | Altered Intercellular Communication | We aimed to evaluate the association of neutrophil to lymphocyte ratio (NLR) as indicator of systemic inflammation with diabetic retinopathy and nephropathy. | 25853704 |
| Refractory anemias, Rheumatoid Arthritis, Inflammation | Altered Intercellular Communication | This study aimed at a systematic evaluation of soluble HLA-G (sHLA-G) in plasma of rheumatoid arthritis (RA) patients with long-lasting chronic inflammation. | 25853899 |
| Refractory anemias, Inflammation | Altered Intercellular Communication | Thus, in a substantial number of late RA patients, the circulating sHLA-G molecules are impaired regarding LILRB1 recognition, meaning that although increased levels are observed; these molecules are not qualified to exert their protective functions against inflammation. | 25853899 |
| Inflammation | Altered Intercellular Communication | Intraventricular fibrinolysis with tissue plasminogen activator is associated with transient cerebrospinal fluid inflammation: a randomized controlled trial. | 25853905 |
| Inflammation | Altered Intercellular Communication | Adjusting for age, gender, and smoking, a higher symptom burden was associated with increased sinonasal inflammation as captured by the MLM (b = 0.453, p < 0.013). | 25854318 |
| Inflammation, Rheumatoid Arthritis | Altered Intercellular Communication | [Etanercept inhibits synovial inflammation and reduces the expression of adhesion related molecules in synovial tissues of patients with rheumatoid arthritis]. | 25854571 |
| Inflammation, Rheumatoid Arthritis, Tumor necrosis | Altered Intercellular Communication | To observe the changes of synovial inflammation score and expression of related molecular markers in patients with rheumatoid arthritis treated with tumor necrosis factor (TNF) antagonist etanercept. | 25854571 |
| Rheumatoid Arthritis, Inflammation | Altered Intercellular Communication | Etanercept could effectively inhibit proliferation of synoviocytes and infiltration of lymphocytes in synovium of rheumatoid arthritis, and decrease the expressions of proliferation-and adhesion-related molecular markers, which histologically alleviated the synovial inflammation of rheumatoid arthritis. | 25854571 |
| Degenerative polyarthritis, Inflammation | Altered Intercellular Communication | We have previously shown that the cartilage DNA methylome delineates two clusters of osteoarthritic (OA) hip patients, characterised by differential methylation of inflammatory genes, while others have demonstrated a link between zinc homeostasis and inflammation in OA. | 25854584 |
| Degenerative polyarthritis | Altered Intercellular Communication | One of the OA clusters is characterised by the promoter hypomethylation and increased expression of inflammation-associated genes including IL1A and TNF. | 25854584 |
| APP gene, Inflammation, Aortic Aneurysm, Abdominal | Altered Intercellular Communication | The main histopathological features of abdominal aortic aneurysm (AAA) are tissue proteolysis mediated by matrix metalloproteinases (MMPs) and inflammation. | 25854712 |
| Inflammation | Altered Intercellular Communication | Mean inflammation score; serum levels of 3 serum markers were then compared. | 25854786 |
| Inflammation, Chronic gastritis | Altered Intercellular Communication | The combination of triple therapy with CoQ10 demonstrated an effective outcome on the mucosal inflammation, and stress oxidative in patients with chronic gastritis. | 25854786 |
| Celiac Disease, Gluten, Inflammation | Altered Intercellular Communication | Gluten consumption is associated with increased plasma a2-macroglobulin in young adults, which appears to be independent of celiac disease, suggesting possible effects of gluten on inflammation. | 25855121 |
| Inflammation, myonecrosis | Altered Intercellular Communication | Statin-associated NAM is characterized by irritable myopathy on electromyography (EMG) and muscle necrosis with minimal inflammation on muscle biopsy. | 25855481 |
| Inflammation, Carcinogenesis, Neoplasms | Altered Intercellular Communication | Evidence suggests an etiologic role for inflammation in ovarian carcinogenesis and heterogeneity between tumor subtypes and anthropometric indices. | 25855626 |
| Inflammation, Kidney Failure, Acute | Altered Intercellular Communication | Inflammation has an integral role in the pathophysiology of AKI. | 25855775 |
| Inflammation, Diabetes Mellitus | Altered Intercellular Communication | Additional adjustment for putative mediators, including subclinical CVD, diabetes, lipids and inflammation, did not significantly affect these estimates. | 25855796 |
| Sepsis, vascular inflammations | Altered Intercellular Communication | Angiopoietin-2 is an endothelial-derived protein that potentiates vascular inflammation and leakage and may be involved in sepsis pathogenesis. | 25855898 |
| Inflammation | Altered Intercellular Communication | The genes hypomethylated in athero-prone arteries to compare with atherosclerotic-resistant arteries were predominately involved in regulation of inflammation and immune processes, as well as development. | 25856389 |
| Pain Distress Question, Endophthalmitis, CTCAE, Retinal Hemorrhage, Inflammation | Altered Intercellular Communication | A 70-year-old woman presented with signs of acute-onset endophthalmitis within 24 hours of surgery, with retinal hemorrhages and vascular changes in the absence of pain or significant inflammation. | 25856829 |
| Inflammation, Endophthalmitis, CTCAE, Retinal Vasculitis, Hemorrhage | Altered Intercellular Communication | Although rarely, acute-onset postoperative endophthalmitis can present as retinal vasculitis with intraretinal hemorrhages and mild inflammation. | 25856829 |
| Autoimmune Diseases, Rheumatoid Arthritis, Orchitis | Altered Intercellular Communication | Rheumatoid arthritis is an autoimmune disease of unknown etiology, characterized by articular inflammation. | 25857584 |
| Inflammation | Altered Intercellular Communication | High level of ICAM-1 may be indicative of systemic inflammation and portends increase risk of incipient DKD. | 25857767 |
| Inflammation, Fibrosis Assessment | Altered Intercellular Communication | Preclinical data suggest these cells improve vascular density, which would be expected to decrease fibrosis and inflammation. | 25857908 |
| Inflammation, Fibrosis Assessment | Altered Intercellular Communication | There were no significant differences in fibrosis or inflammation between groups; however, density of activated fibroblasts was decreased in both CD34+ and CD34- injected areas. | 25857908 |
| Refractory anemias, Inflammation | Altered Intercellular Communication | Biopsies were also obtained from patients with RA with longer symptom duration (>12 weeks) and individuals with no clinically apparent inflammation. | 25858640 |
| Inflammation, Asthma | Altered Intercellular Communication | Some patients with refractory asthma have evidence of uncontrolled eosinophilic inflammation in the distal airways. | 25858909 |
| Airway structure, Asthma | Altered Intercellular Communication | Specifically treating distal airway inflammation may improve asthma control. | 25858909 |
| Eosinophilic disorder, Inflammation | Altered Intercellular Communication | These data demonstrate that patients with ongoing eosinophilic inflammation are not truly refractory, and that suppression of airway eosinophilia may be maintained with additional inhaled corticosteroid. | 25858909 |
| Inflammation, Neoplasms, Communicable Diseases, Congenital vascular anomaly, Disease | Altered Intercellular Communication | Solitary pulmonary nodules (SPNs) can be manifested in a variety of disorders including neoplasms, infection, inflammation, and vascular or congenital abnormalities. | 25860214 |
| Inflammation, Arthritis | Altered Intercellular Communication | All rheumatology and internal medicine practitioners belonging to the Club Rhumatismes et Inflammation in France were sent newsletters asking for reports of HEV infection and inflammatory arthritides. | 25860212 |
| Inflammation, MS gene | Altered Intercellular Communication | Biomarkers of inflammation and axonal degeneration/damage in patients with newly diagnosed multiple sclerosis: contributions of the soluble CD163 CSF/serum ratio to a biomarker panel. | 25860354 |
| MS gene | Altered Intercellular Communication | Expression of soluble CD163 (sCD163), a macrophage/microglia biomarker, is increased in inflammatory conditions, and sCD163 levels in the cerebrospinal fluid (CSF) have recently been shown to be elevated in patients with multiple sclerosis (MS): the sCD163 CSF/serum ratio was elevated in patients with relapsing-remitting MS (RRMS), primary progressive MS (PPMS), and clinically isolated syndrome (CIS) compared with symptomatic controls. | 25860354 |
| Saccular Aneurysm, Rupture, Blood Clot | Altered Intercellular Communication | Although several studies have suggested that aneurysmal wall inflammation and laminar thrombus are associated with the rupture of saccular aneurysms, the mechanisms leading to the rupture remain obscure. | 25860660 |
| Aneurysmal, Inflammation, Endothelial dysfunction, Rupture | Altered Intercellular Communication | These findings suggest that subintimal fibrin deposition and chronic inflammation have a strong impact on degeneration of the aneurysmal wall leading to their rupture, and this finding may be caused by endothelial dysfunction. | 25860660 |
| Inflammation, Ulcer | Altered Intercellular Communication | We studied the eventual apoptosis of epithelial cells from the point of view of ulcer and inflammation. | 25861801 |
| Inflammation, Structure of vasa vasorum | Altered Intercellular Communication | IL-17 overexpression was observed mainly in arteries with transmural inflammation and vasa vasorum vasculitis. | 25862016 |
| Inflammation, Cutaneous Small Vessel Vasculitis | Altered Intercellular Communication | IL-9 overexpression and Th9 polarization predominated in arteries with transmural inflammation and small-vessel vasculitis. | 25862016 |
| Inflammation, Cutaneous Small Vessel Vasculitis | Altered Intercellular Communication | IL-4, TGF-b and thymic stromal lymphopoietin, which are involved in the differentiation of Th9 cells, were overexpressed in arteries with transmural inflammation and small-vessel vasculitis. | 25862016 |
| Inflammation | Altered Intercellular Communication | IL-9R was also overexpressed in GCA arteries with transmural inflammation and was accompanied by increased expression of IL-8. | 25862016 |
| Inflammation, Carcinoma of lung | Altered Intercellular Communication | The high expression of PD-L1 in EBV and inflammation associated LELC may provide a rationale for immunotherapy in this subtype of lung cancer. | 25862146 |
| SLC25A20 gene, Colitis | Altered Intercellular Communication | Females show a lower incidence probably related to hormonal factors; therefore, a role of estrogen receptors (ERs) has been supposed in carcinoma-associated colitis (CAC) development. | 25862314 |
| Alzheimers Disease", Inflammation, Data types - Address, Dyslipidemias | Altered Intercellular Communication | Epidemiological findings suggest a relationship between Alzheimer disease (AD), inflammation, and dyslipidemia, although the nature of this relationship is not well understood. | 25862742 |
| Inflammation, Neoplasm Metastasis, Neoplasms | Altered Intercellular Communication | Axillary lymph node metastasis was not associated with age, menopausal status, primary tumor size or its location, the degree of inflammation within the tumor or mitotic count. | 25862826 |
| Parkinson Disease, Inflammation | Altered Intercellular Communication | Potential of the cannabinoid CB(2) receptor as a pharmacological target against inflammation in Parkinson's disease. | 25863279 |
| Parkinson Disease, Inflammation, palladium | Altered Intercellular Communication | Inflammation is an important pathogenic factor in Parkinson's disease (PD), so that it can contribute to kill dopaminergic neurons of the substantia nigra and to enhance the dopaminergic denervation of the striatum. | 25863279 |
| Infiltration | Altered Intercellular Communication | Parkinsonian inflammation can be reproduced experimentally in rodents by intrastriatal injections of lipopolysaccharide (LPS) which, through an intense activation of glial elements and peripheral infiltration, provokes a rapid deterioration of the striatum that may extend to the substantia nigra too. | 25863279 |
| ACSM3 gene, Inflammation, Subarachnoid Hemorrhage | Altered Intercellular Communication | Subarachnoid haemorrhage (SAH) is associated with sympathetic nervous activation and inflammation. | 25864536 |
| Inflammation | Altered Intercellular Communication | Although there is emerging evidence that these sulphur compounds stimulate immune cells and induce the inflammatory cascade, the immunological mechanisms of local and systemic inflammation have not been described. | 25864743 |
| Inflammation, Critical Illness, Blood Coagulation Disorders | Altered Intercellular Communication | The role of platelet-derived microparticles (PDMPs) in the crosstalk between coagulopathy and inflammation in critically ill patients remains unclear. | 25864886 |
| Diabetic Nephropathy, Inflammation, Fibrosis Assessment | Altered Intercellular Communication | Inflammation and fibrosis play important roles in the progression of diabetic nephropathy. | 25865428 |
| Inflammation, Retinitis Pigmentosa, polychondritis, Autoimmune Disorder, CTCAE | Altered Intercellular Communication | Relapsing polychondritis (RP) is a rare systemic autoimmune disorder characterized by the episodic and progressive deterioration of cartilage inflammation. | 25867227 |
| Inflammation | Altered Intercellular Communication | Among the GFM lesions, GNAS mutations were more common in lesions without active inflammation. | 25867268 |
| Inflammation | Altered Intercellular Communication | Innate immunity plays a pivotal role in obesity-induced low-grade inflammation originating from adipose tissue. | 25867514 |
| Inflammation, Obesity | Altered Intercellular Communication | In vivo, TLR-3 deficiency did not significantly influence HFD-induced obesity, insulin sensitivity or inflammation. | 25867514 |
| Inflammation | Altered Intercellular Communication | However, TLR-3 appears to play a redundant role in obesity-induced inflammation and insulin resistance. | 25867514 |
| Sepsis, Tumor necrosis, Communicable Diseases | Altered Intercellular Communication | Monocyte Tumor Necrosis Factor-a-Converting Enzyme Catalytic Activity and Substrate Shedding in Sepsis and Noninfectious Systemic Inflammation. | 25867908 |
| Acute Kidney Tubular Necrosis, Interstitial Fibrosis Assessment, Interstitial inflammation | Altered Intercellular Communication | Renal biopsy indicated severe acute tubular necrosis with a significant striped interstitial fibrosis and mild interstitial inflammation. | 25868963 |
| Inflammation, Neoplasms | Altered Intercellular Communication | The prognostic nutritional index (PNI), an indicator of nutritional status and systemic inflammation, is associated with survival in several types of tumors. | 25869028 |
| Inflammation, Primary malignant neoplasm | Altered Intercellular Communication | There is accumulating evidence that inflammation is linked to cancer development and progression. | 25869448 |
| Inflammation | Altered Intercellular Communication | These interfaces among inflammation and thrombogenesis have been suggested as targets for pharmacological intervention to reduce disease progression. | 25869506 |
| Vitritis, Intraocular inflammation, Abnormally opaque structure (morphologic abnormality), Uveitis | Altered Intercellular Communication | Intermediate uveitis is a subset of intraocular inflammation where vitritis is the most consistent sign, with or without snowball opacities or snow banks over the pars plana. | 25870216 |
| Candida albicans, Inflammation, Uveitis | Altered Intercellular Communication | Oral fluconazole and intravitreal amphotericin B injection had failed to resolve her inflammation when Candida albicans was identified as the cause of her persistent intermediate uveitis. | 25870216 |
| Inflammation, Knee joint | Altered Intercellular Communication | Does subclinical inflammation contribute to impairment of function of knee joints in aged individuals? | 25870315 |
| Inflammation, Impaired | Altered Intercellular Communication | These data suggest a substantial contribution of inflammation in progressive impairment of joint function with age. | 25870315 |
| Inflammation | Altered Intercellular Communication | Pre-exposure to Ti particles attenuated NF-kB activation in LPS-stimulated macrophages, indicating that wear particles suppress immune response, which may lead to chronic inflammation. | 25871260 |
| Inflammation | Altered Intercellular Communication | Wear particles induce ROS generation through the NOX signaling pathway, resulting in persistent inflammation and delayed loosening. | 25871260 |
| Inflammation, Colorectal Carcinoma | Altered Intercellular Communication | Diet is a strong moderator of systemic inflammation, an established risk factor for colorectal cancer (CRC). | 25871645 |
| Inflammation, Colorectal Carcinoma, Chronic disease | Altered Intercellular Communication | The DII may serve as a novel way to evaluate dietary risk for chronic disorders associated with inflammation, such as CRC. | 25871645 |
| Degenerative polyarthritis, Inflammation, Bone Marrow | Altered Intercellular Communication | Based on pathological, magnetic resonance imaging (MRI) and arthroscopy studies, progressive osteoarthritis involves all tissues of the joint and includes bone marrow lesions, synovial proliferation, fat pad inflammation, and high subchondral bone turnover. | 25872665 |
| Inflammation | Altered Intercellular Communication | Osteopontin (OPN) can recruit macrophages to the site of inflammation and promote tumorigenesis. | 25872762 |
| Acute Coronary Syndrome, Inflammation, GDC AJCC Clinical Stage Terminology | Altered Intercellular Communication | In acute coronary syndrome (ACS), inflammation and redox response are associated with increased residual platelet reactivity (RPR) on clopidogrel therapy. | 25873769 |
| Autosomal Recessive Disorder, Inflammation, Calcinosis, Hyperpigmentation, CTCAE 3 | Altered Intercellular Communication | Ochronosis, an autosomal recessive metabolic disorder, causes an excess of homogentisic acid that results in adverse pigmentation, calcification, and inflammation of cartilaginous and other tissues. | 25873809 |
| Inflammation, Abnormal degeneration | Altered Intercellular Communication | Calcified human aortic valves showed side-specific elevation of superoxide in the endothelium, co-localized with high VCAM1 expression, linking oxidative stress, inflammation, and valve degeneration. | 25874717 |
| Inflammation | Altered Intercellular Communication | TNFa-driven VEC oxidative stress causes loss of endothelial protective function, chronic inflammation, and fibrogenic and osteogenic activation, mitigated differentially by BH4 and peg-SOD. | 25874717 |
| Inflammation, Agoraphobia | Altered Intercellular Communication | Evidence for chronic low-grade systemic inflammation in individuals with agoraphobia from a population-based prospective study. | 25875094 |
| Inflammation, Anxiety Disorders, Coronary heart disease | Altered Intercellular Communication | Anxiety disorders have been linked to an increased risk of incident coronary heart disease in which inflammation plays a key pathogenic role. | 25875094 |
| Inflammation, Agoraphobia | Altered Intercellular Communication | Our results suggest an increase in chronic low-grade inflammation in agoraphobia over time. | 25875094 |
| Colorectal Carcinoma | Altered Intercellular Communication | Laparoscopic surgery for colorectal cancer is not associated with an increase in the circulating levels of several inflammation-related factors. | 25875151 |
| Colorectal Carcinoma | Altered Intercellular Communication | To test this hypothesis, the levels of multiple inflammation-related circulating factors were analyzed in patients undergoing surgery for colorectal cancer. | 25875151 |
| Primary malignant neoplasm, Colorectal Carcinoma | Altered Intercellular Communication | These findings suggest that expression levels of several cytokines are higher in colorectal cancer patients compared to control subjects and no significant increase in several inflammation-related circulating factors is observed following laparoscopic surgery for cancer. | 25875151 |
| Gastritis, Neoplasms | Altered Intercellular Communication | Contrast-enhanced computed tomography (CT) revealed that the tumor had a cystic component and marked perigastric inflammation. | 25875550 |
| Inflammation | Altered Intercellular Communication | The lesion was diagnosed as gastric heterotopic pancreas with inflammation of the pancreatic tissue. | 25875550 |
| Inflammation, Pathology | Altered Intercellular Communication | In human epidemiology studies, the low-grade and chronic systemic inflammation in elderly has been correlated with the development of aging related pathologies. | 25875575 |
| Inflammation | Altered Intercellular Communication | By studying the Drosophila fat body and gut, we have uncovered a mechanism by which lamin-B loss in the fat body upon aging induces age-associated systemic inflammation. | 25875575 |
| Inflammation, Hyperplasia | Altered Intercellular Communication | This chronic inflammation results in the repression of gut local immune response, which in turn leads to the over-proliferation and mis-differentiation of the intestinal stem cells, thereby resulting in gut hyperplasia. | 25875575 |
| Inflammation, Fibrosis Assessment, Heart failure | Altered Intercellular Communication | Galectin-3 (Gal-3) is an emerging biomarker in heart failure that is involved in fibrosis and inflammation. | 25875595 |
| Rectovaginal Fistula, Inflammation | Altered Intercellular Communication | Pelvic MRI demonstrated a possible rectovaginal fistula with inflammation surrounding the right sciatic nerve plexus. | 25876521 |
| Inflammation, IgG4-Related Sclerosing Disease, Head and neck structure | Altered Intercellular Communication | Role of F-18 FDG PET/CT in assessing IgG4-related disease with inflammation of head and neck glands. | 25877159 |
| Inflammation, Atherosclerosis, Refractory anemias, Cardiovascular Diseases, Cyclophosphamide/Vincristine/Dacarbazine Regimen, Rheumatoid Arthritis | Altered Intercellular Communication | This prospective followup study investigated subclinical atherosclerosis in relation to traditional cardiovascular disease (CVD) risk factors and inflammation in patients with rheumatoid arthritis (RA) recruited at diagnosis compared with controls. | 25877503 |
| Inflammation, Bipolar Disorder | Altered Intercellular Communication | Low-grade inflammation predicts persistence of depressive symptoms. | 25877654 |
| Muscle damage, Inflammation, Pain Distress Question | Altered Intercellular Communication | Comparison of markers for muscle damage, inflammation, and pain using minimally invasive direct anterior versus direct lateral approach in total hip arthroplasty: A prospective, randomized, controlled trial. | 25877694 |
| Inflammation, Kaposi Sarcoma, OXSM gene | Altered Intercellular Communication | Inflammation and reactive oxygen species (ROS) production have recently considered as key mechanisms in the pathogenesis of Kaposi's sarcoma (KS). | 25879916 |
| Sarcoidosis, Inflammatory abnormality of the eye | Altered Intercellular Communication | Sarcoidosis is a major cause of ocular or periocular inflammation. | 25880323 |
| Sepsis, Inflammation | Altered Intercellular Communication | Despite a medical treatment and surgical debridement, the sepsis was not controlled, and severe inflammation developed. | 25880377 |
| Inflammation, polyps | Altered Intercellular Communication | Although USD is most likely to represent chronic inflammation, there exists a fair likelihood of finding malignant pathology, particularly in cases where patients have a unilateral polyp. | 25880633 |
| Inflammation, Aortic Aneurysm, Abdominal | Altered Intercellular Communication | Aortic iron overload with oxidative stress and inflammation in human and murine abdominal aortic aneurysm. | 25882069 |
| Tissue damage, Inflammation | Altered Intercellular Communication | Although iron is an essential element for maintaining physiological function, excess iron leads to tissue damage caused by oxidative stress and inflammation. | 25882069 |
| APP gene, Inflammation, Aortic Aneurysm, Abdominal | Altered Intercellular Communication | Oxidative stress and inflammation play critical roles for the development of abdominal aortic aneurysm (AAA). | 25882069 |
| Inflammation | Altered Intercellular Communication | However, it has not been investigated whether iron plays a role in AAA formation through oxidative stress and inflammation. | 25882069 |
| Inflammation, Atheroma | Altered Intercellular Communication | Atheroma may be associated with mild chronic inflammation present in the intima or associated with plaques and adventitia. | 25882155 |
| Inflammation, Osteoporosis, Atherosclerosis | Altered Intercellular Communication | Systemic inflammation may be a common mechanism for the development of osteoporosis (OP) and atherosclerosis. | 25882272 |
| Primary malignant neoplasm, Neoplasms | Altered Intercellular Communication | Primary Tumor Resection in Patients With Metastatic Colorectal Cancer Is Associated With Reversal of Systemic Inflammation and Improved Survival. | 25882598 |
| ARCN1 gene, Inflammation, Wheezing, Hypoxemia, Asthma | Altered Intercellular Communication | Airflow obstruction was correlated with the patient's age at diagnosis, as well as the presence of combined COPD and asthma, and wheezing on auscultation, which also resulted in more severe systemic inflammation and hypoxemia. | 25882894 |
| Inflammation | Altered Intercellular Communication | Brain morphology links systemic inflammation to cognitive function in midlife adults. | 25882911 |
| Inflammation, Impaired cognition | Altered Intercellular Communication | Inflammation is linked to cognitive decline in midlife, but the neural basis for this link is unclear. | 25882911 |
| Presenile dementia, Inflammation | Altered Intercellular Communication | One possibility is that inflammation associates with adverse changes in brain morphology, which accelerates cognitive aging and later dementia risk. | 25882911 |
| Inflammation | Altered Intercellular Communication | Higher peripheral inflammation was associated with poorer spatial reasoning, short term memory, verbal proficiency, learning and memory, and executive function, as well as lower cortical gray and white matter volumes, hippocampal volume and cortical surface area. | 25882911 |
| Inflammation | Altered Intercellular Communication | Exploratory analyses of body mass suggested that adiposity may be a source of the inflammation linking brain morphology to cognition. | 25882911 |
| Inflammation, Impaired cognition | Altered Intercellular Communication | Inflammation and adiposity might relate to cognitive decline via influences on brain morphology. | 25882911 |
| Intraocular inflammation | Altered Intercellular Communication | Visual acuity was 20/20, there was no intraocular inflammation and the posterior vitreous was not detached. | 25884156 |
| Inflammation | Altered Intercellular Communication | Six cases were remission-relapsing type and six were chronic inflammation type. | 25884202 |
| Tissue damage | Altered Intercellular Communication | High mobility group box-1 (HMGB1), a kind of pro-inflammatory mediator, is associated with inflammatory conditions and tissue damage. | 25884225 |
| Inflammation, Primary malignant neoplasm | Altered Intercellular Communication | Inflammation is one of the major hallmarks of cancer. | 25884401 |
| Inflammation, Adenoma of large intestine | Altered Intercellular Communication | These findings suggest colorectal adenoma prevalence may not be associated with significant alterations in systemic inflammation. | 25884547 |
| Communicable Diseases, Inflammation | Altered Intercellular Communication | Tertiary lymphoid structures (TLS) are highly organized immune cell aggregates that develop at sites of inflammation or infection in non-lymphoid organs. | 25884667 |
| Inflammation, Carcinogenesis, Neoplasms | Altered Intercellular Communication | Inflammation plays an integral role in carcinogenesis and tumor progression. | 25885254 |
| Granulomatous inflammation, Caseous necrosis, Tuberculosis | Altered Intercellular Communication | Excisional biopsies performed from two different sites revealed swellings in muscular layers and histopathology showed granulomatous inflammation with caseous necrosis consistent with tuberculosis. | 25885776 |
| Inflammation, Spondylitis, Inflammatory disorder | Altered Intercellular Communication | Ankylosing spondylitis (AS) is an inflammatory disease with documented elevated cardiovascular (CV) risk due to systemic inflammation and a higher prevalence of CV risk factors. | 25886634 |
| Inflammation, Diabetes Mellitus, Non-Insulin-Dependent | Altered Intercellular Communication | Hostile individuals with Type 2 diabetes may be susceptible to stress-induced increases in inflammation. | 25886832 |
| Stomach Carcinoma, Gastrointestinal inflammation | Altered Intercellular Communication | The FJI procedure promotes nutritional recovery and decreases post-operative complications in gastric cancer patients after total gastrectomy, which may be through ameliorating intestinal inflammation and damage and reducing ICC loss to preserve food reservoir function and intestinal motility. | 25886854 |
| Communicable Diseases, Inflammation | Altered Intercellular Communication | Urinary ATP as an indicator of infection and inflammation of the urinary tract in patients with lower urinary tract symptoms. | 25886951 |
| Communicable Diseases, Inflammation | Altered Intercellular Communication | We tested the potential of urinary ATP in the assessment of lower urinary tract symptoms, infection and inflammation, and validated sampling methods for clinical practice. | 25886951 |
| Urologic Diseases | Altered Intercellular Communication | Adenosine-5'-triphosphate (ATP) is a neurotransmitter and inflammatory cytokine implicated in the pathophysiology of lower urinary tract disease. | 25886951 |
| Inflammatory Bowel Diseases, Inflammation | Altered Intercellular Communication | Further, the aberrant miRNA expression profiles indicate that miRNAs may be contributory to IBD pathogenesis, or at least reflect the underlying inflammation. | 25886994 |
| Inflammation, Dental Plaque | Altered Intercellular Communication | Local production of C-reactive protein (CRP) in human coronary arterial plaque was reported as a possible marker for local inflammation and vulnerable plaque. | 25886998 |
| Inflammation, Dental Plaque | Altered Intercellular Communication | Integrated backscatter intravascular ultrasound (IB-IVUS) plaque tissue characterization may detect vulnerable plaque with high local plaque inflammation. | 25886998 |
| Migraine Disorders, Inflammation, Neuronal Hyperexcitability | Altered Intercellular Communication | Recent insights into the pathogenesis of migraine headache substantiate a neuronal hyperexcitability and inflammation involving compressed peripheral craniofacial nerves, and these trigger points can be eliminated by surgery. | 25887206 |
| Inflammation | Altered Intercellular Communication | The mechanism of IR may be associated with inflammation, whereas the neutrophil-lymphocyte ratio (NLR) is a new indicator of subclinical inflammation. | 25887236 |
| Sepsis, Inflammation, Acute Lung Injury, Cessation of life | Altered Intercellular Communication | Sepsis refers to severe systemic inflammation leading to acute lung injury (ALI) and death. | 25887405 |
| Inflammation, Peri-Implantitis | Altered Intercellular Communication | Peri-implantitis is a chronic inflammation, resulting in loss of supporting bone around implants. | 25887438 |
| Inflammation, GDC Disease Response Terminology | Altered Intercellular Communication | Inflammation is supposed to participate in the development of DR. | 25887518 |
| Respiratory Distress Syndrome, Adult, Pneumonitis | Altered Intercellular Communication | Recent studies have revealed that lung inflammation mediated by CD4+ T cells may contribute to the pathogenesis of acute respiratory distress syndrome (ARDS). | 25887535 |
| Autoimmune Diseases, Inflammation | Altered Intercellular Communication | The imbalance between CD4 + CD25 + Foxp3 + regulatory T (Treg) cells and T helper (Th)17 cells has been found in a number of different inflammation and autoimmune diseases, while the role of the Th17/Treg balance in ARDS remains largely unknown. | 25887535 |
| Inflammation, Depression, CTCAE, Atherosclerosis | Altered Intercellular Communication | Growing evidence suggests that there is an intricate interplay between atherosclerosis, inflammation and depression. | 25888123 |
| Minimal Disseminated Disease, Inflammation | Altered Intercellular Communication | The aim of this study was to investigate the role of atherosclerosis-induced inflammation in the mediation of MDD. | 25888123 |
| Inflammation, Hypertension, CTCAE, Obesity | Altered Intercellular Communication | We investigated the relation between inflammation and incident hypertension, independent of obesity, and tested the associations of cardiorespiratory fitness (fitness) and indexes of inflammation for the development of hypertension in 2,475 normotensive men. | 25888302 |
| Inflammation, Carcinoma of lung, Lung, HIV Infections | Altered Intercellular Communication | Our data suggest that pulmonary damage and inflammation associated with HIV infection may be causative for the increased risk of lung cancer. | 25888645 |
| Inflammation, Fever, CTCAE, Trap medical device | Altered Intercellular Communication | TRAPS is clinically characterized by recurrent episodes of long-lasting fever and systemic inflammation. | 25888769 |
| Degenerative polyarthritis, Arthritis | Altered Intercellular Communication | Based on our data, cathepsin activity monitored by ABPs correlated well with OA severity and joint inflammation, directing towards a novel etiological target for OA, which possesses significant translational potential in developing means for non-invasive detection of early signs of OA. | 25889265 |
| Degenerative polyarthritis | Altered Intercellular Communication | Lysosomal cathepsins have been reported to contribute to Osteoarthritis (OA) pathophysiology due to their increase in pro-inflammatory conditions. | 25889265 |
| Inflammation, Atherosclerosis | Altered Intercellular Communication | Pitavastatin not only improved the atherosis as measured by IMT and cIBS values but also attenuated inflammation of plaques as measured by max SUV at the same site. | 25889304 |
| Vascular Diseases, Inflammation | Altered Intercellular Communication | Vascular disease is promoted by systemic inflammation that can arise from sites distal to the affected vessels. | 25890092 |
| Inflammation, Exanthema, Polymyositis, Idiopathic Inflammatory Myopathies, Dermatomyositis | Altered Intercellular Communication | Dermatomyositis and polymyositis are both types of idiopathic inflammatory myositis characterized by inflammation and weakness of proximal skeletal muscles and skin rash. | 25890160 |
| Inflammation, Sleep Apnea, Obstructive | Altered Intercellular Communication | Obstructive Sleep Apnea (OSAS) is a disease associated with the increase of cardiovascular risk and it is characterized by repeated episodes of Intermittent Hypoxia (IH) which inducing oxidative stress and systemic inflammation. | 25890226 |
| Refractory anemias, Rheumatoid Arthritis, Hormone abnormality | Altered Intercellular Communication | Rheumatoid arthritis (RA) is characterized by decreased androgen levels, which was the first hormonal abnormality described. | 25890314 |
| Inflammation, Rheumatoid Arthritis, Calcium pyrophosphate deposition disease | Altered Intercellular Communication | Extensor digitorum tendon (EDT) tear in the wrist is frequently associated with inflammation (rheumatoid arthritis, chondrocalcinosis) or distal radio-ulnar osteoarthritis. | 25890810 |
| methyldopa, Inflammation, Age related macular degeneration | Altered Intercellular Communication | Dysfunction of the retinal pigment epithelium (RPE) resulting from chronic inflammation is implicated in the pathogenesis of age-related macular degeneration (AMD). | 25890876 |
| Seizures, Inflammation, Epilepsy | Altered Intercellular Communication | Recently, a growing body of evidence has suggested that microRNA-146a (miR-146a) is upregulated in the brains of epilepsy patients and of mouse models; furthermore, miR-146a may be involved in the development and progression of seizures through the regulation of inflammation and immune responses. | 25891929 |
| Crohn Disease, Inflammation | Altered Intercellular Communication | Two patients had established Crohn's disease, both with long segments (>95 mm) of transmural inflammation located >100 mm from the diverticulum. | 25892011 |
| Inflammation, Carcinogenesis, Malignant Neoplasms | Altered Intercellular Communication | Inflammation is an important hallmark of all types of cancers with a well-established role in carcinogenesis. | 25892571 |
| Inflammation, Intervertebral Disc Degeneration | Altered Intercellular Communication | Chronic inflammation is a key component of painful intervertebral disc degeneration. | 25893355 |
| Sepsis, Inflammation | Altered Intercellular Communication | Plasma Neutrophil Gelatinase-Associated Lipocalin Is Primarily Related to Inflammation during Sepsis: A Translational Approach. | 25893429 |
| Inflammation, Kidney Failure, Acute | Altered Intercellular Communication | Plasma neutrophil gelatinase-associated lipocalin (plasma-NGAL) is discussed as new biomarker for AKI diagnosis, but during inflammation its function and diagnostic impact remain unclear. | 25893429 |
| Sepsis, Inflammation, Injury of kidney | Altered Intercellular Communication | Plasma-NGAL levels were stronger associated with inflammation markers including IL-6 (Sepsis: r = 0.785 P < 0.001; chronic inflammation after anti-TNF: r = 0.558 P < 0.001), IL-8 (Sepsis: r = 0.714 P<0.004; healthy controls after exercise r = 0.786 P < 0.028; chronic inflammation before anti-TNF: r = 0.429 P < 0.041) and IL-10 (healthy controls before exercise: r = 0.791 P < 0.028) than with kidney injury or function. | 25893429 |
| Inflammation, Kidney Failure, Acute | Altered Intercellular Communication | For clinical relevance, it might not only be useful for AKI detection during severe inflammation - indeed it has to be interpreted carefully within this setting - but additionally might offer therapeutic potential. | 25893429 |
| Communicable Diseases, Inflammation | Altered Intercellular Communication | Thus, our data suggest that persistent HPV16/18 infection in the cervix due to the presence of the HLA-DQB1 A-allele and chronic inflammation due to the presence of the IL-1b -511 T-allele might predispose women to CaCx development. | 25893807 |
| Inflammation | Altered Intercellular Communication | Oxidative stress and chronic inflammation are factors accelerating telomere loss. | 25894013 |
| Inflammation | Altered Intercellular Communication | Chronic hemodialysis, typically accompanied by oxidative stress and inflammation, may be also associated with replicative senescence. | 25894013 |
| Inflammation, Amyloidosis | Altered Intercellular Communication | Bone marrow biopsy provides important information in renal transplant recipients, especially in cases of neoplastic bone marrow involvement, specific inflammation, and amyloidosis, which are uncommon in this patient group. | 25894168 |
| Inflammation | Altered Intercellular Communication | It may be explained by reduced erythropoietin (EPO) synthesis, but recent data suggest that EPO-resistance and diminished iron availability due to inflammation contribute significantly. | 25894587 |
| Albrights hereditary osteodystrophy", Parathyroid Hormone Resistance | Altered Intercellular Communication | Reports of patients with mild POH with Albright hereditary osteodystrophy (AHO), specifically pseudohypoparathyroidism type Ia (PHP Ia) with hormonal resistance, suggest the possibility of a common molecular basis. | 25894639 |
| Inflammation, Liver damage | Altered Intercellular Communication | The importance of these prognostic variables suggests a close relationship between inflammation, iron overload, liver damage and the extension of the disease. | 25895906 |
| Intraocular inflammation | Altered Intercellular Communication | High risk was defined as a history of graft rejection, three or more quadrants of vascularization, or the presence or history of intraocular inflammation. | 25896110 |
| Inflammation, Essential Hypertension | Altered Intercellular Communication | Impact of administration of folic acid on selected indicators of inflammation in patients with primary arterial hypertension. | 25897102 |
| Inflammation, Essential Hypertension | Altered Intercellular Communication | The results of epidemiological and clinical tests have shown that in patients with primary arterial hypertension, a chronic mild inflammation develops. | 25897102 |
| Inflammation | Altered Intercellular Communication | Inflammation and inflammatory biomarkers have emerged as integral components and predictors of incident cardiovascular (CV) disease. | 25897795 |
| Inflammation | Altered Intercellular Communication | 3-h exposure to DE caused no genotoxicity, oxidative stress or inflammation in PBMCs, whereas exposure to noise might cause oxidatively damaged DNA. | 25898780 |
| Waldenstrom Macroglobulinemia, Haiti | Altered Intercellular Communication | Patients with a clinical diagnosis of HT had increased lymphoplasmacytic inflammation, but the relative proportion of IgG4+ plasma cells was not increased compared to patients without HT. | 25898816 |
| Vasculitis, Coronary Arteriosclerosis | Altered Intercellular Communication | Influence of cardiovascular risk factors and vessel wall inflammation on atherosclerotic disease progression was analyzed. | 25898891 |
| Airway structure, Asthma, Allergy - Charge Type Reason | Altered Intercellular Communication | In our group of children with asthma, no correlation was found between the level of vitamin D and the degree of airway reactivity, airway inflammation, and allergy. | 25899478 |
| Inflammation | Altered Intercellular Communication | In a relatively small cohort of clinically stable MHD patients, the veterans showed equivalent nutrition status and dietary intake and less inflammation than the nonveterans, thus not supporting the possibility that veteran MHD patients may have worse nutrition than the nonveteran counterpart. | 25899538 |
| Inflammation | Altered Intercellular Communication | Neutrophil-lymphocyte ratio (NLR) and platelet-lymphocyte ratio (PLR) are two new inflammatory markers used in the assessment of systemic inflammation. | 25900081 |
| Inflammation, osteoclast activating factor | Altered Intercellular Communication | Elevated CRP levels, indicating profound inflammation, may be associated with significantly increased risk of POAF in patients with CAD who underwent coronary artery bypass graft. | 25901664 |
| Inflammation | Altered Intercellular Communication | Thus, these results provide an additional line of evidence that IWT is advantageous in promoting health from an epigenetic perspective by ameliorating susceptibility to inflammation. | 25901949 |
| Inflammatory Bowel Diseases, Acute and chronic inflammation | Altered Intercellular Communication | Monocyte and M1 Macrophage-induced Barrier Defect Contributes to Chronic Intestinal Inflammation in IBD. | 25901973 |
| Inflammatory Bowel Diseases, Gastrointestinal inflammation | Altered Intercellular Communication | Lamina propria monocytes and M1 macrophages invading intestinal tissues directly contribute to disrupting the epithelial barrier through deregulation of tight junction proteins and induction of epithelial cell apoptosis, thus driving intestinal inflammation in IBD. | 25901973 |
| Inflammation, Asthma | Altered Intercellular Communication | Definition of the overlap syndrome was based on the coexistence of post-bronchodilation FEV1/FVC < 70% and, either, an asthmatic history before the age of 40, or, at least, two functional and immune-inflammatory asthmatic traits : 1) significant FEV1 reversibility to inhaled bronchodilator (FEVI change >/= 200 ml and >/= 12% after bronchodilation), 2) eosinophilic inflammation : sputum eosinophils >= 3%,blood eosinophils >= 400/ml, or FENO >= 45 ppb, 3) clinical history of airway allergy, or total serum IgE >= 113 KU/l, or RAST >= 0,35 KU/l against major aeroallergens. | 25902605 |
| Inflammation, Coronary Artery Disease | Altered Intercellular Communication | Impact of inflammation, gene variants, and cigarette smoking on coronary artery disease risk. | 25902778 |
| Inflammation, Coronary Artery Disease | Altered Intercellular Communication | The role of inflammation in coronary artery disease (CAD) pathogenesis is well recognized. | 25902778 |
| Inflammation, Atherosclerosis | Altered Intercellular Communication | Multivariate analysis showed an increase in the EPA/AA ratio, but not in the DHA/AA ratio, was associated with effects on atherosclerosis-related markers, especially triglyceride-rich lipoproteins, high-density lipoprotein cholesterol (HDL-C) containing apolipoprotein A-1, and leukocyte count in an anti-atherogenic direction.The results suggest a higher EPA/AA ratio, but not a higher DHA/AA ratio, might be associated with a lower prevalence of CAD and improvements of triglyceride metabolism and HDL metabolism, and systemic inflammation. | 25902881 |
| Inflammation, Adenoma, Serrated Nodule, Colorectal Carcinoma | Altered Intercellular Communication | The candidate markers were analyzed in colonic tissue specimens from patients with colorectal cancer (n = 15), adenomas (n = 76), serrated lesions (n = 13), chronic inflammation (n = 10) and normal mucosal samples (n = 9). | 25902909 |
| Malignant tumor of colon | Altered Intercellular Communication | The methylation markers ITGA4 and TFPI2 seem to be suitable risk markers for inflammation-associated colon cancer. | 25902909 |
| Cholecystitis, Acute Cholecystitis | Altered Intercellular Communication | Is gallbladder inflammation more severe in male patients presenting with acute cholecystitis? | 25903474 |
| Cholecystitis | Altered Intercellular Communication | The extent of gallbladder inflammation has been shown to influence surgical outcome. | 25903474 |
| Cholecystitis, Acute Cholecystitis | Altered Intercellular Communication | The aim of this study was to investigate whether or not gallbladder inflammation is more severe in male patients presenting with acute cholecystitis. | 25903474 |
| Cholecystitis, Gangrene | Altered Intercellular Communication | Severe gallbladder inflammation (gangrenous and necrotizing cholecystitis) was seen in a significant portion of the male population compared to the female population (p = 0.002). | 25903474 |
| Cholecystitis | Altered Intercellular Communication | The male gender is a risk factor for severe gallbladder inflammation. | 25903474 |
| Degenerative polyarthritis, Inflammation, Disease | Altered Intercellular Communication | The Cx43 protein is overexpressed in several human diseases and inflammation processes and in articular cartilage from patients with osteoarthritis (OA). | 25903580 |
| Refractory anemias, Inflammation | Altered Intercellular Communication | These data from a large unselected population suggest that elevated RDW levels in RA patients should prompt physicians to aggressively screen and treat their patients for modifiable cardiovascular (CVS) risk factors, in addition to treating RA inflammation. | 25903822 |
| Sepsis, Inflammation, Chronic Kidney Diseases | Altered Intercellular Communication | Chronic kidney disease (CKD) and systemic inflammation are risk factors for sepsis. | 25903849 |
| Inflammation, Chronic Kidney Diseases | Altered Intercellular Communication | While often viewed as a marker of chronic kidney disease, Cystatin C (Cyst-C) may also reflect systemic inflammation. | 25903849 |
| Epithelial Damage, Inflammation, Hypoxia | Altered Intercellular Communication | In a murine model of intratracheal lipopolysaccharide challenge, dietary-induced vitamin D deficiency resulted in exaggerated alveolar inflammation, epithelial damage and hypoxia. | 25903964 |
| Disability, Inflammation | Altered Intercellular Communication | although recent studies have suggested that inflammation may play an important role in the process of ageing and in the development of disabilities, knowledge about the role of inflammation in physical performance decline among middle-aged and older people in the context of developing countries is limited. | 25904444 |
| Inflammation | Altered Intercellular Communication | Cyclic pressurization of segmentally stiffened aortic segments ex vivo increases the expression of genes related to inflammation and extracellular matrix remodeling. | 25904646 |
| Inflammation, Glioblastoma Multiforme Pathway | Altered Intercellular Communication | Polymorphisms in inflammation, DNA repair, and metabolism pathways are associated with neurocognitive function in glioma patients and may affect clinical outcomes. | 25904748 |
| Inflammation, Fibrosis Assessment | Altered Intercellular Communication | Impact of a low-glucose peritoneal dialysis regimen on fibrosis and inflammation biomarkers. | 25904773 |
| Inflammation, Fibrosis Assessment | Altered Intercellular Communication | The impact of a low-glucose peritoneal dialysis (PD) regimen on biomarkers of peritoneal inflammation, fibrosis and membrane integrity remains to be investigated. | 25904773 |
| Inflammation, Chronic Obstructive Airway Disease | Altered Intercellular Communication | Disruption of Sirtuin 1-Mediated Control of Circadian Molecular Clock and Inflammation in Chronic Obstructive Pulmonary Disease. | 25905433 |
| ARCN1 gene, Cessation of life, Chronic Obstructive Airway Disease, Abnormal inflammatory response | Altered Intercellular Communication | Chronic obstructive pulmonary disease (COPD) is the fourth most common cause of death, and it is characterized by abnormal inflammation and lung function decline. | 25905433 |
| Hypogonadism, AVP gene, Meibomian gland dysfunction | Altered Intercellular Communication | The most common hormonal dysfunctions were diabetes insipidus (n = 7) and hypogonadism (n = 7). | 25906106 |
| Hyperglycemia, Inflammation, Cerebrovascular accident | Altered Intercellular Communication | Association of stroke clinical outcomes with coexistence of hyperglycemia and biomarkers of inflammation. | 25906929 |
| Hyperglycemia, Inflammation, Ischemic stroke | Altered Intercellular Communication | To investigate the association of short-term clinical outcomes with coexistence of hyperglycemia and elevated biomarkers of inflammation among acute ischemic stroke (AIS) patients. | 25906929 |
| Hyperglycemia, Inflammation | Altered Intercellular Communication | This study indicated that hyperglycemia and elevated biomarkers of inflammation were associated with short-term clinical outcomes, and individuals with coexistence of hyperglycemia and elevated biomarkers of inflammation had higher risk of poor clinical outcomes among AIS patients. | 25906929 |
| Inflammation, Observation Method - Coagulation, Atherosclerosis, myocardial injury | Altered Intercellular Communication | In this population-based cohort, variables obtained by CV imaging and biomarkers of inflammation, coagulation, atherosclerosis, myocardial injury and stress, and cardiac collagen turnover were associated with YAL, an important outcome that integrates physical ability and longevity in older persons. | 25907126 |
| Inflammation | Altered Intercellular Communication | TL1A is a TNF-like cytokine which has been shown to co-stimulate TH1 and TH17 responses during chronic inflammation. | 25908025 |
| Inflammation, Carcinogenesis | Altered Intercellular Communication | Biologic activities of functional mediators activate downstream transducers regulating inflammation and carcinogenesis. | 25908103 |
| Inflammation, Malignant Neoplasms, Obesity | Altered Intercellular Communication | Obesity and vitamin D deficiency are associated with risk for several cancers, possibly through inflammation and adipokine-related pathways. | 25908506 |
| Inflammation, Arthritis | Altered Intercellular Communication | Magnetic resonance imaging (MRI) is useful for detecting joint inflammation and damage in the inflammatory arthropathies. | 25908527 |
| Cartilage damage, Gout, Refractory anemias, Rheumatoid Arthritis, Arthritis | Altered Intercellular Communication | This study aimed to investigate MRI cartilage damage and its associations with joint inflammation in patients with gout compared with a group with rheumatoid arthritis (RA). | 25908527 |
| Inflammation, Cyclophosphamide/Vincristine/Dacarbazine Regimen, Chronic Kidney Diseases, Cardiovascular Diseases | Altered Intercellular Communication | The high incidence of cardiovascular disease (CVD) in chronic kidney disease (CKD) is related partially to chronic inflammation. | 25908532 |
| Inflammation | Altered Intercellular Communication | Specialized Proresolving Lipid Mediators (SPMs) derived from the n-3 fatty acids, eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA) actively promote the resolution of inflammation. | 25908532 |
| Inflammation, Chronic Kidney Diseases | Altered Intercellular Communication | This may have important implications for limiting ongoing low grade inflammation in CKD. | 25908532 |
| Tumor necrosis, Inflammation, Deterioration | Altered Intercellular Communication | There is a direct relationship between valve deterioration and the patient's inflammatory status and cytokines: interleukin-6, interleukin-1, tumor necrosis factor, and C-reactive protein, involved in this major state of inflammation. | 25909210 |
| Inflammation, Chronic Kidney Diseases | Altered Intercellular Communication | Association between Inflammation and Cardiac Geometry in Chronic Kidney Disease: Findings from the CRIC Study. | 25909952 |
| Granulomatous inflammation, Granulomatosis with polyangiitis, Systemic disease, Necrotizing vasculitis | Altered Intercellular Communication | Wegener's granulomatosis (WG) is a multisystemic disease of unknown etiology characterized by necrotizing vasculitis and granulomatous inflammation. | 25910303 |
| Inflammation, Actual blood loss, Kidney Failure, Acute | Altered Intercellular Communication | The first CPB haematocrit was independently associated with AKI in the MCPB group (Relative Risk [RR]=0.484, 95% Confidence Interval [CI]=0.268-0.876, p=0.016); post-operative blood loss and inflammation were independently associated with AKI in the CCPB group (RR=1.005, 95%CI=1.003-1.007, p<0.001; RR=1.018, 95%CI=1.010-1.028, p<0.001). | 25910838 |
| Discordance, Inflammation | Altered Intercellular Communication | Discordance (LDL-PNMR > apoB) was associated with insulin resistance, smaller LDL particle size, increased systemic inflammation, and low circulating levels of "traditional" lipids, whereas discordance (apoB > LDL-PNMR) was associated with larger LDL particle size, and elevated levels of lipoprotein(a) and lipoprotein-associated phospholipase A2 (Lp-PLA2). | 25911082 |
| Inflammation, Cystic Fibrosis | Altered Intercellular Communication | Heart involvement in children and adults with cystic fibrosis: correlation with pulmonary indexes and inflammation markers. | 25911142 |
| Renal Insufficiency, Inflammation, Respiratory physiology | Altered Intercellular Communication | We hypothesise that such cardiac impairments may gradually arise due to preceding chronic inflammation related to prior degeneration of lung function and thus it is very important to keep patients clinically stable and address chronic inflammation as early as possible in the progression of CF. | 25911142 |
| Inflammation | Altered Intercellular Communication | Joint inflammation detected at extremity MRI was the secondary outcome. | 25911456 |
| MTTP wt Allele | Altered Intercellular Communication | With MRI-detected inflammation as outcome, the sensitivity and specificity were 39% and 86% and 31% and 69% for the test at the MCP and MTP joints, respectively. | 25911456 |
| Inflammation | Altered Intercellular Communication | A positive squeeze test is associated with local joint inflammation but the sensitivity is low, indicating a high percentage of swollen joints with a negative squeeze test. | 25911456 |
| Inflammation, Nasopharyngeal carcinoma | Altered Intercellular Communication | Increasing evidences suggest that NO promotes inflammation induced growth of nasopharyngeal carcinoma (NPC). | 25912222 |
| Inflammation, Diabetes Mellitus | Altered Intercellular Communication | We investigated established diabetes biomarkers that could implicate potential mechanistic pathways, including C-reactive protein (CRP), a marker of systemic inflammation; gamma glutamyl transferase (GGT), a liver enzyme associated with oxidative stress; and adiponectin, an adipokine modulating glucose regulation and fatty acid oxidation. | 25913152 |
| Inflammation, Thrombosis, atherosclerotic | Altered Intercellular Communication | p38MAPK is an important element of inflammatory pathways in atherothrombosis and its inhibition may lead to reduced inflammation within atherosclerotic plaques. | 25913664 |
| Inflammatory Bowel Diseases, Inflammation, Carcinoma | Altered Intercellular Communication | Our data demonstrate a high rate of pre-operatively undetected high-grade IENs and carcinoma and a frequent multifocal occurrence in IBD patients with long-standing inflammation of the colon. | 25913799 |
| Gingivitis, Dental Plaque | Altered Intercellular Communication | Performance of a light fluorescence device for the detection of microbial plaque and gingival inflammation. | 25914048 |
| Gingivitis, Dental Plaque | Altered Intercellular Communication | The SOPROCARE fluorescence tool in perio-mode provides reliable evaluation of microbial plaque and gingival inflammation for the dental clinician. | 25914048 |
| Inflammation, Liver carcinoma, Liver Cirrhosis, Liver Failure | Altered Intercellular Communication | The final sequalae of cirrhosis, liver failure and hepatocellular carcinoma are often the result of inflammation driven by intrahepatic lymphocytes. | 25914090 |
| Orchitis | Altered Intercellular Communication | Nineteen proteins were altered by nicotine in the model of articular inflammation, including several cytokines and proteases. | 25914226 |
| Inflammation, Breast Carcinoma, Pain Distress Question | Altered Intercellular Communication | Consequently, the purpose of our work is to identify some biochemical parameters involved in the events cascade associated with inflammation and pain in breast cancer female patients, monitored in dynamics of anesthesia and surgical procedure. | 25914735 |
| Eyelid Diseases, Inflammatory abnormality of the eye, Dryness (characteristic), Ocular Surface Disease Index, Eyelid Neoplasms | Altered Intercellular Communication | Common ophthalmological problems are found in patients with eyelid tumors and include ocular surface diseases, such as dry eyes, eyelid disorders, excessive tearing and ocular inflammation. | 25914748 |
| Colonic Polyps | Altered Intercellular Communication | Low Prevalence of Colon Polyps in Chronic Inflammatory Conditions of the Colon. | 25916222 |
| Colonic Polyps | Altered Intercellular Communication | Chronic inflammatory conditions of the colon are associated with a decreased prevalence of colon polyps. | 25916222 |
| Inflammation | Altered Intercellular Communication | The histological analysis demonstrated low to moderate inflammation, displaying areas of inflammatory infiltrate in the bone marrow. | 25916730 |
| Sample Size Calculation, Fibrosis Assessment, Inflammation | Altered Intercellular Communication | Systemic sclerosis (SSc) is characterized by chronic inflammation and fibrosis. | 25917089 |
| Inflammation, N-Formylmethionine | Altered Intercellular Communication | N-Formyl peptide (fMLF) receptors (FPRs) are chemotactic receptors involved in inflammation. | 25917089 |
| Inflammation, Acute inflammation, prostatitis | Altered Intercellular Communication | The number of IELs in both around and inside inflammation areas correlated to the grade and location of HP (P < 0.0001 and P < 0.0003), the presence of acute glandular inflammation (P < 0.0001), the scattered stromal lymphocytes (P = 0.029), and BPH and PIN associated prostatic inflammation (P < 0.0001). | 25917232 |
| Inflammation, Asthma | Altered Intercellular Communication | Exhaled breath temperature (EBT) reflects airways (both eosinophilic and neutrophilic) inflammation in asthma and thus may aid the management of children with asthma that are treated with anti-inflammatory drugs. | 25917297 |
| Airway structure | Altered Intercellular Communication | A new EBT monitor has become available that is cheap and easy to use and may be a suitable monitoring device for airways inflammation. | 25917297 |
| Airway structure, Asthma | Altered Intercellular Communication | Little is known about how EBT relates to asthma treatment decisions, disease control, lung function, or other non-invasive measures of airways inflammation, such as exhaled nitric oxide (ENO). | 25917297 |
| Inflammation, Carcinoma of lung | Altered Intercellular Communication | The present findings add to the evidence implicating inflammation in lung cancer etiology. | 25917613 |
| Inflammation, Rheumatoid Arthritis | Altered Intercellular Communication | Leucine-rich a2 -glycoprotein as a potential biomarker for joint inflammation during anti-interleukin-6 biologic therapy in rheumatoid arthritis. | 25917892 |
| Refractory anemias, Inflammation, Arthritis | Altered Intercellular Communication | Under conditions of IL-6 inhibition, LRG was more useful than other biomarkers in discriminating between active and inactive disease in human RA and in detecting joint inflammation in experimental arthritis. | 25917892 |
| Inflammation, Encrusted cystitis, Bacterial Infections, Corynebacterium | Altered Intercellular Communication | Encrusted cystitis is a rare condition characterized by encrustation of the bladder mucosa with associated chronic inflammation induced by urea-splitting bacterial infection--most commonly, Corynebacterium urealyticum. | 25918192 |
| Hepatitis, Chronic, Hepatocarcinogenesis | Altered Intercellular Communication | Chronic liver inflammation modifies DNA methylation at the precancerous stage of murine hepatocarcinogenesis. | 25918251 |
| Liver carcinoma, Hepatitis, Chronic, FAM126A gene | Altered Intercellular Communication | Chronic liver inflammation precedes the majority of hepatocellular carcinomas (HCC). | 25918251 |
| Inflammation, FAM126A gene | Altered Intercellular Communication | Here, we explore the connection between chronic inflammation and DNA methylation in the liver at the late precancerous stages of HCC development in Mdr2(-/-) (Mdr2/Abcb4-knockout) mice, a model of inflammation-mediated HCC. | 25918251 |
| Inflammation | Altered Intercellular Communication | Chronic inflammation did not change global levels of DNA methylation in Mdr2(-/-) liver, but caused a 2-fold decrease of the global 5-hydroxymethylcytosine level in mutants compared to controls. | 25918251 |
| Hepatitis, Chronic | Altered Intercellular Communication | Our findings demonstrate that chronic liver inflammation causes hypermethylation of specific CGIs, which may affect both hepatocytes and non-hepatocyte liver cells. | 25918251 |
| Hyperparathyroidism, Structure of thick cushion of skin on foot | Altered Intercellular Communication | Neither hyperparathyroidism nor inflammation malnutrition syndrome was found to contribute to the formation of oral tori in chronic hemodialysis patients. | 25918724 |
| Communicable Diseases, Granulomatous inflammation | Altered Intercellular Communication | Granulomatous inflammation is considered an immune mechanism against infection or certain non-neoplastic conditions. | 25918980 |
| Inflammation, Corneal Endothelial Cell Loss | Altered Intercellular Communication | Activated leukocytes may produce free oxygen radicals and endothelial damage, and, thereby, increased inflammation and thrombogenesis. | 25919135 |
| Reduction mammaplasty, Inflammation, Pain, Postoperative | Altered Intercellular Communication | Pulsed electromagnetic fields have been shown to reduce postoperative pain, inflammation, and narcotic requirements after breast reduction and augmentation surgical procedures. | 25919263 |
| Inflammation, Atrial Fibrillation, Atrial Fibrillation by ECG Finding, Heart failure | Altered Intercellular Communication | There is mounting evidence to support the influence of inflammation and oxidative stress in the pathogenesis of atrial fibrillation (AF) and heart failure (HF). | 25919281 |
| Inflammation, Complications of Diabetes Mellitus, Diabetes Mellitus | Altered Intercellular Communication | Chronic inflammation from diabetes mellitus effects glycemic control and increases risk of diabetes complications. | 25920299 |
| Inflammation, Fibrosis Assessment, Edema | Altered Intercellular Communication | Fibroblast proliferation, fibrosis, perivascular inflammation, oedema, vascular proliferation and vascular wall thickness were determined and scored in all specimens. | 25920601 |
| Inflammation, Fibrosis Assessment, Hyperplasia, Tenosynovitis | Altered Intercellular Communication | Synovial hyperplasia, fibrosis and perivascular inflammation were not observed in tenosynovial analysis of both groups. | 25920601 |
| Inflammation, Fibrosis Assessment, Edema | Altered Intercellular Communication | There was no oedema, fibrosis and perivascular inflammation of the epineurium in specimens of either group. | 25920601 |
| Inflammation, Interneurons, Abnormality of mitochondrial metabolism | Altered Intercellular Communication | Localised selective GABAergic interneuron loss in layers IV and VI was related to GMLs but was not explained by the presence of inflammation or by mitochondrial dysfunction within Type I GMLs. | 25921040 |
| Inflammation, Malignant Neoplasms | Altered Intercellular Communication | Chronic inflammation could affect the occurrence and development of malignant tumors. | 25921150 |
| Small cell carcinoma of lung, Primary malignant neoplasm | Altered Intercellular Communication | Advanced Lung Cancer Inflammation Index, a New Prognostic Score, Predicts Outcome in Patients With Small-Cell Lung Cancer. | 25922292 |
| Acute Lung Injury, Primary malignant neoplasm, Small cell carcinoma of lung | Altered Intercellular Communication | This report is the first to use the value of the Advanced Lung Cancer Inflammation Index (ALI) to predict the overall survival in patients with small-cell lung cancer. | 25922292 |
| Acute Lung Injury, Primary malignant neoplasm, Non-Small Cell Lung Carcinoma | Altered Intercellular Communication | A recent study indicated that the Advanced Lung Cancer Inflammation Index (ALI) could predict overall survival (OS) in patients with non-small-cell lung cancer. | 25922292 |
| Inflammation, Plasma/serum xenobiotic | Altered Intercellular Communication | Plasma/serum levels of several biomarkers of inflammation and oxidative stress and nitrite/nitrate were assessed upon admission and 24 h after STEMI onset in patients treated by primary percutaneous coronary intervention. | 25922551 |
| Inflammation, Macular edema due to diabetes mellitus | Altered Intercellular Communication | A variety of cytokines associated with inflammation and angiogenesis may contribute to the pathogenesis of diabetic macular edema, and both anti-inflammatory and antiangiogenic agents should be included in the treatment of ME simultaneously. | 25923230 |
| Cholesteatoma, Inflammation | Altered Intercellular Communication | Postoperatively, cholesteatoma samples were analyzed by immunostaining for MPO positivity as a marker for acute inflammation. | 25923274 |
| Inflammation | Altered Intercellular Communication | Transcription factor Kruppel-like factor 6 (KLF6)-myeloid-specific conditional deficient mice exhibit this aortic phenotype when subjected to aortic inflammation. | 25923510 |
| Pancreatic calcification, Inflammation, Pancreas, Diabetes Mellitus | Altered Intercellular Communication | Fibrocalculous Pancreatic Diabetes is a unique entity wherein pancreatic calcification and chronic inflammation lead to exocrine and endocrine failure of the pancreas. | 25924662 |
| Acute Q fever, Chronic Q Fever, Fever, CTCAE | Altered Intercellular Communication | To identify the immune mechanisms responsible for ineffective clearance of Coxiella burnetii in patients who developed chronic Q fever, we compared serum concentrations of 47 inflammation-associated markers among patients with acute Q fever, vascular chronic Q fever, and past resolved Q fever. | 25924761 |
| Inflammation, Angina Pectoris, Electrocardiogram: myocardial infarction (finding), Dyslipidemias, atherosclerotic | Altered Intercellular Communication | Inflammation and dyslipidaemia may play an important role in the development of atherosclerotic complications, for example myocardial infarction and angina pectoris. | 25924966 |
| HD Term Type, Inflammation | Altered Intercellular Communication | PTX3 may be considered a novel biomarker of inflammation in HD patients. | 25924996 |
| vascular inflammations, Depression, CTCAE, Cardiomyopathies | Altered Intercellular Communication | However, patients with more frequent wine consumption had a significantly better perception of health status (Kansas City Cardiomyopathy Questionnaire score, adjusted P<0.0001), less frequent symptoms of depression (Geriatric Depression Scale, adjusted P=0.01), and lower plasma levels of biomarkers of vascular inflammation (osteoprotegerin and C-terminal proendothelin-1, adjusted P<0.0001, and pentraxin-3, P=0.01) after adjusting for possible confounders. | 25925415 |
| vascular inflammations, Chronic heart failure, Depression, CTCAE | Altered Intercellular Communication | We show for the first time in a large cohort of patients with chronic heart failure that moderate wine consumption is associated with a better perceived and objective health status, lower prevalence of depression, and less vascular inflammation, but does not translate into more favorable clinical 4-year outcomes. | 25925415 |
| Inflammation | Altered Intercellular Communication | Nuclear enzyme poly(ADP-ribose) polymerase 1 (PARP-1) is associated with inflammation response. | 25926140 |
| Inflammation | Altered Intercellular Communication | These data suggested that PARP-1 inhibition prevents IL-1b-induced inflammation response at least partly by inhibiting the IL-1R/NF-kB signaling pathway in human articular chondrocytes. | 25926140 |
| Prostate carcinoma | Altered Intercellular Communication | Association between Serum Phospholipid Fatty Acids and Intraprostatic Inflammation in the Placebo Arm of the Prostate Cancer Prevention Trial. | 25926387 |
| Inflammation, Prostate carcinoma | Altered Intercellular Communication | Inflammation may play an etiologic role in prostate cancer. | 25926387 |
| Degenerative polyarthritis, Arthritis | Altered Intercellular Communication | The purpose of this study was to evaluate synovial fluid from knees with and without OA for potential markers of joint inflammation and degradation and to correlate these findings with radiographic severity of disease. | 25927354 |
| Inflammation, animal organ regeneration | Altered Intercellular Communication | Specifically, the aged mice showed systemic inflammation and organ degeneration. | 25927599 |
| Inflammation, Degenerative disorder | Altered Intercellular Communication | These findings showed for the first time that arginine 213 in the HBD of SOD3 is critical for maintaining proper organ function through moderating the normal innate immune response, which would otherwise lead to chronic inflammation and degenerative diseases in aged mice. | 25927599 |
| Degenerative polyarthritis, Inflammation, Facet joint structure | Altered Intercellular Communication | In this study we conducted an in situ analysis of IL-6 expression at different sites of inflammation in zygapophyseal joints of patients with AS in comparison to osteoarthritis autopsy controls (CO). | 25928402 |
| Inflammation | Altered Intercellular Communication | The relevance of pro-inflammatory agents in axial SpA might be studied better in situ in bony specimens at the primary site of inflammation. | 25928402 |
| Have Autoimmune or Inflammatory Condition | Altered Intercellular Communication | The expression of Th1-specific cytokines, known to be associated with autoimmune inflammation (i.e. | 25928531 |
| Limbic Encephalitis, Inflammation, Immune-mediated | Altered Intercellular Communication | Limbic encephalitis, an immune-mediated encephalitis, results from inflammation in the medial temporal lobes. | 25929634 |
| Inflammation, Intracranial Aneurysm, Rupture, Aneurysm | Altered Intercellular Communication | Inflammation and degeneration of the intracranial saccular aneurysm wall play a major role in aneurysm formation, development and subsequent rupture. | 25929881 |
| Inflammation | Altered Intercellular Communication | TLR4 gene polymorphism may take part in the development of chronic inflammation in women after menopause, which is the cause of severe bone resorption. | 25931355 |
| Chronic kidney disease stage 5, Inflammation, Kidney Failure, Chronic, Immunologic Deficiency Syndromes | Altered Intercellular Communication | Patients with end stage renal disease (ESRD) suffer from chronic inflammation, leading to a secondary, uremic immunodeficiency associated with alterations in monocyte subpopulations with increased proinflammatory capacities. | 25931358 |
| Kidney Failure, Chronic, Inflammation | Altered Intercellular Communication | This indicates that chronic inflammation may substantiate the biased consistence of monocyte subpopulations leading to profound alteration in DC generation and maturation in ESRD. | 25931358 |
| Chronic abscess, hormone deficiency | Altered Intercellular Communication | A chronic abscess state may be the most important factor associated with permanent hormone deficiency. | 25932567 |
| Inflammation, Malnutrition, Pellagra, Flaky paint dermatosis | Altered Intercellular Communication | In this case series we provide evidence that malnourished patients with flaky paint dermatosis and infection/inflammation shown laboratory data suggestive of indoleamine 2,3-dioxygenase (IDO) activation, besides decreased urinary excretion of N1-methylnicotinamide (N1 MN), a marker of pellagra. | 25933499 |
| Communicable Diseases, Inflammation, Flaky paint dermatosis | Altered Intercellular Communication | We study nine adult patients showing flaky paint dermatosis and clinical features of infection or inflammation, and increased serum C-reactive protein, characteristic of the presence of acute phase response syndrome. | 25933499 |
| Cerebellar Diseases | Altered Intercellular Communication | The alteration in GABAA receptor-dependent neurotransmission is a potential mechanism for ethanol-induced cerebellar dysfunction. | 25933648 |
| Inflammation, Hypertension, CTCAE, Cardiovascular Diseases | Altered Intercellular Communication | Hypertension and inflammation may contribute to the increased risk of cardiovascular disease in individuals with suboptimal sleep, but large prospective studies are lacking. | 25934538 |
| Squamous cell carcinoma of esophagus | Altered Intercellular Communication | A novel inflammation-based prognostic score in esophageal squamous cell carcinoma: the C-reactive protein/albumin ratio. | 25934640 |
| Primary malignant neoplasm | Altered Intercellular Communication | Plenty of studies have demonstrated the prognostic value of various inflammation-based indexes in cancer. | 25934640 |
| Squamous cell carcinoma of esophagus | Altered Intercellular Communication | The CRP/Alb ratio is a novel but promising inflammation-based prognostic score in esophageal squamous cell carcinoma. | 25934640 |
| Airway structure, Asthma | Altered Intercellular Communication | Future studies should investigate the impact of exercise intensity and exercise training on airway inflammation in those with asthma. | 25935433 |
| Inflammation, Cardiac sarcoidosis | Altered Intercellular Communication | Inflammation and oxidative stress play a crucial role in the pathogenesis of cardiac sarcoidosis (SAR). | 25935620 |
| Vasculitis, Leukocytoclastic, Cutaneous | Altered Intercellular Communication | Cutaneous small vessel vasculitis is a severe neutrophilic vascular inflammation mediated by immune complexes that involves the dermal postcapillary venules. | 25935914 |
| Pyelonephritis, Chronic inflammation, Obstruction, Kidney Diseases, Kidney Calculi | Altered Intercellular Communication | Xanthogranulomatous pyelonephritis is an uncommon disorder of the kidney that is characterised by chronic inflammation and extensive destruction of the involved kidney usually associated with renal calculus and obstruction. | 25935947 |
| Inflammation, Arthritis, Psoriasis, Skin lesion | Altered Intercellular Communication | In conclusion, H2 administration reduced inflammation associated with psoriasis in the three cases examined and it may therefore be considered as a treatment strategy for psoriasis-associated skin lesions and arthritis. | 25936373 |
| Heart Diseases, Inflammation | Altered Intercellular Communication | The aim of this study was a prospective evaluation of the inflammation parameters in patients with different forms of AF without structural heart disease. | 25936571 |
| Inflammation, Left Bundle-Branch Block, Myocardial | Altered Intercellular Communication | Of 92 patients, 34 developed LBBB without more advanced myocardial damage or inflammation biomarkers in comparison with patients without LBBB. | 25937352 |
| Inflammation, Left Bundle-Branch Block, Myocardial | Altered Intercellular Communication | In conclusion, after TAVI, 37% of patients developed new LBBB without more advanced myocardial damage or inflammation biomarkers. | 25937352 |
| vascular inflammations, Muscle, Smooth, Vascular | Altered Intercellular Communication | SM22a inhibits vascular inflammation via stabilization of IkBa in vascular smooth muscle cells. | 25937534 |
| Vascular Diseases | Altered Intercellular Communication | SM22a may be a novel therapeutic target for human vascular diseases and other inflammatory conditions. | 25937534 |
| Airway structure, ARCN1 gene | Altered Intercellular Communication | These longitudinal changes may be due to increasing airway inflammation or to progression of COPD. | 25938279 |
| Inflammation, Electrocardiogram: myocardial infarction (finding), Aortic Valve Stenosis | Altered Intercellular Communication | Elevated Lipoprotein(a) Does Not Cause Low-Grade Inflammation Despite Causal Association With Aortic Valve Stenosis and Myocardial Infarction: A Study of 100,578 Individuals from the General Population. | 25938632 |
| Inflammation, Electrocardiogram: myocardial infarction (finding), Aortic Valve Stenosis | Altered Intercellular Communication | We tested the hypothesis that elevated lipoprotein(a) is observationally and causally associated with low-grade inflammation together with aortic valve stenosis and myocardial infarction. | 25938632 |
| Inflammation, Aortic Valve Stenosis | Altered Intercellular Communication | Elevated levels of lipoprotein(a) were not causally associated with increased low-grade inflammation as measured through CRP despite a causal association with increased risk of aortic valve stenosis and MI. | 25938632 |
| Inflammation, Intestinal Microbiome | Altered Intercellular Communication | The current model for disease suggests that genetically susceptible patients develop intolerance to gut microflora, and chronic inflammation develops as a result of environmental insults. | 25939040 |
| Inflammation, Prostate carcinoma | Altered Intercellular Communication | Intraprostatic inflammation is positively associated with serum PSA in men with PSA <4 ng ml(-1), normal DRE and negative for prostate cancer. | 25939516 |
| Inflammation, Prostate carcinoma | Altered Intercellular Communication | However, the influence of intraprostatic inflammation on serum PSA in men without biopsy indication and negative for prostate cancer has not been described in detail. | 25939516 |
| Inflammation | Altered Intercellular Communication | Median percentage of tissue area with inflammation increased from 2 to 5 to 9.5% across PSA tertiles (P-trend <0.0001). | 25939516 |
| Inflammation | Altered Intercellular Communication | Median extent and intensity scores increased across PSA tertiles in luminal and intraepithelial compartments for acute inflammation and in stromal and intraepithelial compartments for chronic inflammation (all P-trend <=0.05). | 25939516 |
| Inflammation, Prostate carcinoma | Altered Intercellular Communication | In men without clinical suspicion of prostate cancer, greater overall inflammation, luminal and intraepithelial acute inflammation and stromal and intraepithelial chronic inflammation were associated with higher serum PSA. | 25939516 |
| Lesion Restenosis Indicator, Inflammation | Altered Intercellular Communication | On histopathology, the restenosis lesion at the SES-deployed site showed greater inflammation and less re-endothelialization than that at the BMS-deployed site. | 25939630 |
| Inflammation, Atherosclerosis | Altered Intercellular Communication | Drug-eluting stents still have problems of persistent inflammation, inappropriate neointima formation, and neoatherosclerosis. | 25939630 |
| Inflammation, Cardiac valve calcification, Malnutrition, Atherosclerosis | Altered Intercellular Communication | Periaortic Fat Tissue: A Predictor of Cardiac Valvular Calcification, Malnutrition, Inflammation, and Atherosclerosis Components in Hemodialysis Patients. | 25940595 |
| Kidney Failure, Chronic, Inflammation, Cardiac valve calcification, Malnutrition, Atherosclerosis, Calcinosis | Altered Intercellular Communication | Cardiac valvular calcification (CVC) in end-stage renal disease is shown to be a component of malnutrition, inflammation, atherosclerosis, calcification (MIAC) syndrome. | 25940595 |
| HD Term Type, Inflammation | Altered Intercellular Communication | In this study, T-PAFT showed a positive correlation with inflammation, CVC, and MIAC score in HD patients. | 25940595 |
| Inflammation, Rosacea | Altered Intercellular Communication | Recombinant erythroid differentiation regulator 1 inhibits both inflammation and angiogenesis in a mouse model of rosacea. | 25940661 |
| Abnormal inflammatory response, Hyperactive behavior, Rosacea, Inflammatory disorder | Altered Intercellular Communication | Rosacea is a chronic inflammatory skin disorder that is characterized by abnormal inflammation and vascular hyperactivity of the facial skin. | 25940661 |
| Inflammation, Erythema, Telangiectasis | Altered Intercellular Communication | LL-37 injection induced typical rosacea features, including erythema, telangiectasia and inflammation. | 25940661 |
| Inflammation, Rosacea | Altered Intercellular Communication | Taken together, our findings suggest that rErdr1 may be involved in attenuating the inflammation and angiogenesis associated with the pathogenesis of rosacea. | 25940661 |
| Inflammation, Lymphocytic infiltration, Necrosis, Osteolysis | Altered Intercellular Communication | These tribocorrosion-related tissue reactions are characterized by marked necrosis and lymphocytic infiltration, which contrasts sharply with the macrophagic and foreign body giant cell inflammation associated with polyethylene wear particle induced peri-implant osteolysis. | 25940887 |
| Inflammation, Cutaneous, Lupus Erythematosus | Altered Intercellular Communication | They also develop spontaneous skin inflammation similar to the cutaneous lesions common in human lupus erythematosus. | 25941899 |
| Proteinuria, Glomerular filtration, Nephritis | Altered Intercellular Communication | The Y group showed the greatest decrease in anti-dsDNA antibodies, organ weight, degree of kidney inflammation and glomerular infiltration of C3, and incidence rate of severe proteinuria; the E, L, and CT treatment groups showed better results than the C group. | 25941899 |
| Inflammation, Sensitization (observable entity) | Altered Intercellular Communication | The beryllium bronchoalveolar lavage lymphocyte proliferation test: indicator of beryllium sensitization, inflammation or both? | 25942054 |
| Pneumonitis, Sensitization (observable entity) | Altered Intercellular Communication | The objective was to describe the contribution of the BeBALLPT to classification of workers with respect to beryllium sensitization (BeS) and beryllium-induced lung inflammation. | 25942054 |
| Granulomatous inflammation | Altered Intercellular Communication | We analyzed factors influencing BeBALLPT outcome, and its relation to blood-determined BeS and granulomatous inflammation. | 25942054 |
| Pneumonitis | Altered Intercellular Communication | Positive BeBALLPTs contributed evidence of BeS in subjects without prior positive beryllium blood lymphocyte proliferation tests (BeBLPTs) and of pulmonary inflammation in persons without granulomata evident on lung biopsy. | 25942054 |
| Granuloma, Pneumonitis | Altered Intercellular Communication | A positive BeBALLPT is closely linked to the presence of granulomata on lung biopsy and can be considered as an indicator of lung inflammation in addition to BeS. | 25942054 |
| Pneumonitis | Altered Intercellular Communication | It is not recommended that a positive BeBALLPT be considered sufficient evidence for both lung inflammation and BeS. | 25942054 |
| ARCN1 gene, Inflammation | Altered Intercellular Communication | Heightened inflammation, including expression of COX-2, is associated with COPD pathogenesis. | 25943190 |
| ARCN1 gene, Inflammation | Altered Intercellular Communication | Our data indicate that RelB attenuates COX-2 expression in lung structural cells, such that loss of pulmonary RelB may be an important determinant in the aberrant, heightened inflammation associated with COPD pathogenesis. | 25943190 |
| Inflammation, Ulcerative Colitis | Altered Intercellular Communication | Furthermore, we found a clear correlation between stromal caspase-4 and -5 expression levels, inflammation and disease activity in ulcerative colitis patients. | 25943872 |
| Inflammatory Bowel Diseases, Colorectal Carcinoma, Gastrointestinal inflammation | Altered Intercellular Communication | Deregulated intestinal inflammation in IBD patients is associated with an increased risk of developing CRC. | 25943872 |
| Proteinuria, Cardiac fibrosis, Nephritis, Tumor necrosis, Glomerulosclerosis (disorder) | Altered Intercellular Communication | This fluid retention was associated with an increase in blood pressure, proteinuria, renal inflammation with macrophage infiltration and tumor necrosis factor-a overexpression, glomerular sclerosis, and cardiac fibrosis. | 25944876 |
| Inflammation, Neoplasms | Altered Intercellular Communication | GROb (CXCL2) is a chemokine produced by endotoxin-treated macrophages that mediates inflammation and tumor development. | 25944970 |
| Inflammation, Atrophic | Altered Intercellular Communication | On the other hand, normal mucosa was defined as mucosa not demonstrating histological abnormalities, including inflammation and atrophy. | 25945015 |
| Inflammation, Burn injury | Altered Intercellular Communication | Matrix metalloproteinases (MMPs) -8 and -9 are released from neutrophils in acute inflammation and may contribute to permeability changes in burn injury. | 25945788 |
| Inflammation, Atherosclerosis | Altered Intercellular Communication | NLRP3 is involved in inflammation that leads to atherosclerosis. | 25946654 |
| Data types - Address | Altered Intercellular Communication | Blood platelets contain the neurotransmitter serotonin and amyloid-precursor protein (APP), and may thus be useful as a peripheral biomarker for AD. | 25947203 |
| Inflammation, Pathologic Neovascularization, GDC Disease Response Terminology | Altered Intercellular Communication | Persistent inflammation and impaired neovascularisation may be important contributors to the development of DR. A recent study showed that toll-like receptor 4 (TLR4) polymorphisms were associated with DR. | 25947554 |
| IgG4-Related Sclerosing Disease, Orbital Pseudotumor | Altered Intercellular Communication | IgG4-related disease in idiopathic sclerosing orbital inflammation. | 25947555 |
| Inflammation, Rheumatoid Arthritis, Primary malignant neoplasm | Altered Intercellular Communication | What is the impact of chronic systemic inflammation such as rheumatoid arthritis on mortality following cancer? | 25948597 |
| Inflammation, Primary malignant neoplasm | Altered Intercellular Communication | Emerging evidence links inflammation and immune competence to cancer progression and outcome. | 25948597 |
| Inflammation, Obesity | Altered Intercellular Communication | The environmental and behavioral risk factors associated with central obesity and/or inflammation in populations exposed to both obesogenic and pathogenic environments remain unclear. | 25948781 |
| Symptoms, Inflammation | Altered Intercellular Communication | Men with high WHtR with inflammation had higher odds of infectious symptoms than those with high WHtR without inflammation (OR: 1.73; 95% CI: 1.15, 2.61). | 25948781 |
| Gynecomastia | Altered Intercellular Communication | Hormonal work ups for gynaecomastia all turned out normal, thus isolating the drug as the cause. | 25948845 |
| Inflammation | Altered Intercellular Communication | We also determined whether baseline levels of inflammation markers and immune activation were independently associated with BMD loss. | 25948863 |
| Inflammation | Altered Intercellular Communication | Inflammation and immune activation/senescence before ART initiation independently predicted subsequent BMD loss. | 25948863 |
| ARCN1 gene | Altered Intercellular Communication | Airway IL-1b and Systemic Inflammation as Predictors of Future Exacerbation Risk in Asthma and COPD. | 25950204 |
| ARCN1 gene, Inflammation, Asthma, Exacerbation | Altered Intercellular Communication | This study aimed to investigate airway innate immune activation and systemic inflammation as predictors of exacerbations in asthma and COPD. | 25950204 |
| Airway structure, Inflammation, Exacerbation | Altered Intercellular Communication | The relationships among airway inflammation, systemic inflammation, and future exacerbations were examined using path analysis. | 25950204 |
| Inflammation, Asthma | Altered Intercellular Communication | Systemic inflammation was also associated with increased exacerbation risk in asthma. | 25950204 |
| ARCN1 gene, Inflammation, Exacerbation | Altered Intercellular Communication | Airway IL-1b and systemic inflammation are associated with frequent exacerbations and may mediate a vicious cycle between previous and future exacerbations in COPD. | 25950204 |
| Macular Edema, Cystoid, Acute inflammation | Altered Intercellular Communication | Although it is presumed to be associated with an inflammatory cascade and possible postoperative inflammation, only 2 cases of SLT complicated by cystoid macular edema have been previously reported. | 25950662 |
| Inflammation, Chronic disease | Altered Intercellular Communication | Our findings did not corroborate any anti-inflammatory effects of testosterone or corresponding potentially protective effects of testosterone on chronic diseases resulting from reduced low-grade systemic inflammation. | 25950910 |
| Inflammation, Damage | Altered Intercellular Communication | Rarefaction significantly increases peripheral resistance which results in elevated blood pressure, leads to vessel damage and induction of inflammation. | 25951297 |
| Inflammation, Hypertensive (finding) | Altered Intercellular Communication | The hypertensive group was also characterized by elevated levels of CRP, VEGF and IL-8 that are the hallmarks of inflammation. | 25951297 |
| Inflammation, Hypertension, CTCAE | Altered Intercellular Communication | Presented results show that hypertension is characterized by imbalance of pro-angiogenic and anti-angiogenic factors in the background of inflammation. | 25951297 |
| Parkinsonian Disorders | Altered Intercellular Communication | However, Parkinson pathology is more widespread in the brain, affecting also other dopaminergic pathways and neurotransmitter systems, but these changes are less well characterized. | 25952735 |
| Degenerative polyarthritis, Inflammation, Atherosclerosis | Altered Intercellular Communication | This might suggest an association between atherosclerosis and knee OA through low-grade systemic inflammation in women. | 25953699 |
| Ischemia, Observation Method - Coagulation, Inflammation, Cerebrovascular accident | Altered Intercellular Communication | BAIPC may safely inhibit stroke recurrence, protect against brain ischemia, and ameliorate plasma biomarkers of inflammation and coagulation in octo- and nonagenarians with SIAS. | 25956401 |
| Ulcerative Colitis | Altered Intercellular Communication | The Impact of Endoscopic Inflammation and Mucosal Healing on Health-related Quality of Life in Ulcerative Colitis Patients. | 25956537 |
| Inflammation, Colitis | Altered Intercellular Communication | Clinical disease activity was assessed by the Simple Clinical Colitis Activity Index [SCCAI], endoscopic inflammation by the Mayo Endoscopic Subscore [MES], and HRQoL by the Short Inflammatory Bowel Disease Questionnaire [SIBDQ] and Short Health Scale [SHS]. | 25956537 |
| Inflammation | Altered Intercellular Communication | Not only clinical disease activity but also endoscopic inflammation and disease extent were associated with decreased HRQoL. | 25956537 |
| Inflammatory Bowel Diseases, Crohn Disease, Gastrointestinal inflammation, Ulcerative Colitis | Altered Intercellular Communication | Inflammatory bowel diseases (IBD), including Crohn's disease (CD) and ulcerative colitis (UC), are characterized by chronic intestinal inflammation due to immunological, microbial, and environmental factors in genetically predisposed individuals. | 25956706 |
| Inflammation | Altered Intercellular Communication | In multivariate analysis, older age (>=50 versus 30-<40 years: prevalence ratio [PR], 2.36; 95% confidence interval [CI], 1.45-3.84, p for trend = 0.001), lower CD4 + cell counts (<100 versus >=200 cells/mm(3): PR, 1.55; 95% CI, 1.01-2.36, p for trend = 0.03) and cervical inflammation (PR, 1.73; 95% CI, 1.16-2.60, p = 0.008) were associated with an increased risk of cervical SIL. | 25957324 |
| Bone Diseases, Protein-Energy Malnutrition | Altered Intercellular Communication | Changes in mineral bone disease, protein-energy wasting/inflammation, and occurrence of adverse events after 1 year. | 25958079 |
| Protein-Energy Malnutrition | Altered Intercellular Communication | There was no evidence of protein-energy wasting/inflammation or aluminum toxicity, and fewer participants randomly assigned to ferric citrate had serious adverse events. | 25958079 |
| Pharyngitis, Atlantoaxial, Syndrome, Joint Subluxations | Altered Intercellular Communication | Grisel syndrome is a nontraumatic rotatory subluxation of the atlantoaxial joint, following nasopharyngeal inflammation or ear, nose, and throat (ENT) procedures. | 25959249 |
| Necrotizing granulomatous inflammation, Propionibacterium | Altered Intercellular Communication | These findings suggest that propionibacteria might be associated with sarcoidosis granulomatous inflammation. | 25959360 |
| Arterial Stiffness, Inflammation, Endothelial dysfunction, glycation | Altered Intercellular Communication | Arterial stiffness is related to inflammation, oxidative stress, advanced glycation end products (AGEs), and endothelial dysfunction. | 25959807 |
| Gingivitis, Inflammation, Bacteremia | Altered Intercellular Communication | We hypothesized that in the development of gingival inflammation, systemic markers of inflammation and bacteremia would increase. | 25960104 |
| Inflammation | Altered Intercellular Communication | Inflammation is important for initiation and progression of the disease. | 25960616 |
| airway disease, Airway Obstruction, Airway structure | Altered Intercellular Communication | The high collapsibility in patients with predominant airway disease, mild airway obstruction, and in women with this phenotype may reflect chronic airway inflammation. | 25960647 |
| Airway structure, Smooth muscle (tissue) | Altered Intercellular Communication | We assessed airway inflammation, reticular basement membrane (RBM) thickness, airway smooth muscle (ASM), mucus gland area, vascularity, and epithelial integrity. | 25961111 |
| Inflammation, Wheezing | Altered Intercellular Communication | Airway morphometrics and inflammation were similar in viral and multiple-trigger wheezers. | 25961111 |
| Inflammation, Wheezing, MS4A2 wt Allele | Altered Intercellular Communication | In preschoolers with severe recurrent wheeze, markers of remodeling and inflammation are unrelated, and atopy is associated with ASM. | 25961111 |
| Inflammation | Altered Intercellular Communication | Albumin concentration is associated with nutrition and inflammation. | 25961608 |
| Inflammation, NCI CTEP SDC Retinoblastoma Sub-Category Terminology | Altered Intercellular Communication | Anterior inflammation is a rare form of masquerade syndrome associated with retinoblastoma; however, it tends to be associated with diffuse posterior segment retinoblastoma when it does occur. | 25961779 |
| Primary malignant neoplasm, Focal acute inflammation, Intestinal Obstruction, Obesity | Altered Intercellular Communication | There are advantages in case of obesity presence (IMT more than 30 kg/m2), in significant shortening of the mesocolon and mesentery, high fixation of splenic flexure and intimate fixation of the spleen, in case of bad preparation of the bowels in partial intestinal obstruction or in case of emergency operation, big cancer size, expressed perifocal inflammation. | 25962296 |
| Primary sclerosing cholangitis, Inflammation, Neoplasms | Altered Intercellular Communication | The risk of neoplasia was not significantly associated with the type of lesion (P = .94 from log-rank test), primary sclerosing cholangitis (P = .94), or active inflammation (P = .41) in this cohort. | 25962315 |
| Inflammation | Altered Intercellular Communication | We hypothesise that longer standing chronic inflammation and older age may cause a less prompt and effective response to treatment in SA when compared with their genetically related controls. | 25962691 |
| Inflammation | Altered Intercellular Communication | Primary outcome measures assessing joint health were serum cartilage oligomeric matrix protein (sCOMP) and knee joint synovial inflammation (Doppler ultrasound colour fraction; CF). | 25962747 |
| Inflammation, Intervertebral Disk Displacement | Altered Intercellular Communication | Markers of inflammation and fibrinolysis in relation to outcome after surgery for lumbar disc herniation. | 25962814 |
| Inflammation, Back Pain, Sciatica | Altered Intercellular Communication | The role of inflammation and fibrinolysis for the development of back pain and sciatica has been discussed. | 25962814 |
| Endothelial dysfunction, Diabetic Angiopathies, Diabetes Mellitus | Altered Intercellular Communication | Pro-inflammatory conditions induced by products of protein glycation in diabetes substantially enhance the risk of endothelial dysfunction and related vascular complications. | 25963575 |
| Refractory anemias, Inflammation, Rheumatoid Arthritis | Altered Intercellular Communication | Tertiary lymphoid structures (TLSs) in chronic inflammation, including rheumatoid arthritis (RA) synovial tissue (ST), often contain high endothelial venules and follicular dendritic cells (FDCs). | 25963989 |
| Inflammation | Altered Intercellular Communication | We established a strong link between NIK(+) ECs, (pre)FDCs, and the presence of TLSs, indicating that NIK(+) ECs may not only be important orchestrators of lymph node development but also contribute to the formation of TLSs in chronic inflammation. | 25963989 |
| Inflammation | Altered Intercellular Communication | In conclusion, our findings indicate that mtDNA variants can mediate methylation profiles and transcription for inflammation, angiogenesis and various signaling pathways, which are important in several common diseases. | 25964427 |
| Inflammation, Behavior Disorders | Altered Intercellular Communication | This may not only delay aging and prolong a youthful healthy life but also delay or prevent onset of several lifestyle-related diseases, of which oxidative stress and inflammation are the chief cause. | 25964984 |
| Inflammation | Altered Intercellular Communication | APN was an important factor for antagonizing inflammation and mitigating IR. | 25966055 |
| vascular inflammations, Atherosclerosis | Altered Intercellular Communication | Sulfatides have been shown to play a role in atherogenesis and vascular inflammation, resulting in atherosclerosis. | 25966258 |
| Inflammation, Inflammatory lesion | Altered Intercellular Communication | The Glasgow Prognostic Score (GPS) measures inflammation and proves its prognostic value in patients with extranodal natural killer (NK)/T-cell lymphoma (ENKTL) which is commonly combined with inflammatory lesion. | 25966773 |
| Tuberculoma, Inflammation, Primary malignant neoplasm, Inflammatory Myofibroblastic Tumor, Neoplasms, Tuberculosis | Altered Intercellular Communication | The corresponding pathological classification results (fungal inflammation, tuberculosis and tuberculoma, inflammatory pseudotumor, tumor middle differentiation, cancer) of quantized patients were treated as dependent variables. | 25967875 |
| Inflammation, Thrombosis, Hyperviscosity, Cerebral Infarction, Diabetic Ketoacidosis, Dehydration | Altered Intercellular Communication | Especially in patients who are genetically prone to thrombosis, cerebral infarction may develop due to inflammation, dehydration, and hyperviscocity secondary to DKA. | 25968433 |
| Glucose Intolerance (disease), Rhabdomyositis | Altered Intercellular Communication | MyD88 regulates physical inactivity-induced skeletal muscle inflammation, ceramide biosynthesis signaling, and glucose intolerance. | 25968578 |
| Inflammation | Altered Intercellular Communication | Elevated inflammation and ceramide biosynthesis have been implicated in metabolic disruption and are linked to Toll-like receptor (TLR)/myeloid differentiation primary response 88 (MyD88) signaling. | 25968578 |
| Diabetes Mellitus | Altered Intercellular Communication | Interaction between Erythrocyte Phospholipid Fatty Acids Composition and Variants of Inflammation-Related Genes on Type 2 Diabetes. | 25969153 |
| Inflammation, Premature Obstetric Labor, Intestinal Obstruction | Altered Intercellular Communication | A 22-year -old woman, at 26 weeks of pregnancy, was admitted for premature labour, intestinal obstruction and systemic inflammation. | 25969480 |
| Cytomegalovirus Infections, Intraocular inflammation | Altered Intercellular Communication | The patient had a confirmed CMV infection as a cause of her intraocular inflammation via PCR DNA testing of an aqueous sample. | 25969485 |
| diabetic | Altered Intercellular Communication | One Egg per Day Improves Inflammation when Compared to an Oatmeal-Based Breakfast without Increasing Other Cardiometabolic Risk Factors in Diabetic Patients. | 25970149 |
| Inflammation, Metabolic Syndrome X | Altered Intercellular Communication | However, we have previously shown that eggs reduce inflammation in patients at risk for T2DM, including obese subjects and those with metabolic syndrome. | 25970149 |
| Inflammation | Altered Intercellular Communication | In contrast, eggs reduce AST and TNF-a in this population characterized by chronic low-grade inflammation. | 25970149 |
| Coronary Artery Disease | Altered Intercellular Communication | Recent studies suggest that the inflammation-associated protein calprotectin may be implicated in the pathogenesis of coronary artery disease (CAD). | 25970343 |
| Airway structure, Asthma, Obesity | Altered Intercellular Communication | Obesity is considered a risk factor for asthma, due to the induction of changes in airway mechanics and altered airway inflammation. | 25970463 |
| Granulomatous inflammation, Granulomatous | Altered Intercellular Communication | Specimens from patients with acute HZ were found to have small numbers of perineural plasma cells and most had subtle granulomatous inflammation, in patterns similar to the group with late granulomatous reactions. | 25970643 |
| Inflammation, Cardiovascular Diseases, Atherosclerosis | Altered Intercellular Communication | Cardiovascular disease is the leading cause of morbidity and mortality in hemodialysis patients; the increased risk of cardiovascular disease is due to accelerated atherosclerosis, inflammation and impaired lipoprotein metabolism. | 25971848 |
| Lesion, Fibrosis Assessment | Altered Intercellular Communication | Plasmin activity was observed almost exclusively in the TI space (mainly in the interstitium and partly in the tubular epithelial cells) and was significantly stronger in patients with TI lesion (tubular atrophy/interstitial fibrosis and tubulointerstitial inflammation) than in those without TI lesion. | 25971850 |
| Inflammation, Fibrosis Assessment, IGA Glomerulonephritis | Altered Intercellular Communication | These data suggest that TI plasmin is associated with TI inflammation leading to renal fibrosis, and can cause the decline in renal function seen in patients with IgAN. | 25971850 |
| Inflammation, Pain Distress Question, Autoimmune Diseases, Rheumatoid Arthritis, Spondylitis, Arthritis, Abnormal degeneration | Altered Intercellular Communication | Rheumatoid arthritis (AR), psoriatic arthritis (PSA) and ankylosing spondylitis (AS) are autoimmune systemic diseases characterized by inflammation, pain and joint degeneration. | 25972066 |
| Inflammation, Endothelial dysfunction, Atherosclerosis | Altered Intercellular Communication | The flavonoids epicatechin (in cocoa and tea) and quercetin (in tea) probably play a role by reducing endothelial dysfunction and inflammation, 2 main determinants of atherosclerosis. | 25972527 |
| Inflammation, Endothelial dysfunction | Altered Intercellular Communication | Plasma biomarkers of endothelial dysfunction and inflammation were measured at the start and end of each 4-wk intervention period. | 25972527 |
| Inflammation, Fibrosis Assessment, Diabetes Mellitus, Non-Insulin-Dependent, Kidney Diseases | Altered Intercellular Communication | A novel panel of biomarkers representing different pathways of renal disease progression including inflammation, fibrosis, angiogenesis, and endothelial function improved prediction of eGFR decline on top of established risk markers in type 2 diabetes. | 25973922 |
| Inflammation, Traumatic injury | Altered Intercellular Communication | Most injuries occur when anatomy is unclear due to the presence of anatomic variations, acute inflammation, or adhesions. | 25974072 |
| Inflammation, Cerebrovascular accident | Altered Intercellular Communication | Inflammation has received increasing attention as a cause of stroke. | 25974422 |
| Refractory anemias, Rheumatoid Arthritis, Inflammatory disorder | Altered Intercellular Communication | Both neutrophil-to-lymphocyte ratio (NLR) and platelet-to-lymphocyte ratio (PLR) are reported to be increased in various inflammation-related diseases, but their clinical significance in rheumatoid arthritis (RA) remains unclear. | 25974992 |
| Inflammation, Carcinogenesis, Primary malignant neoplasm | Altered Intercellular Communication | Inflammation contributes to human carcinogenesis and cancer progression. | 25975177 |
| Inflammation, Chronic sinusitis | Altered Intercellular Communication | Interleukin-25 and interleukin-33 as mediators of eosinophilic inflammation in chronic rhinosinusitis. | 25975248 |
| Inflammation, Chronic sinusitis, Craniosynostosis | Altered Intercellular Communication | The initiating mediators of T-helper 2 inflammation, often seen in eosinophillic chronic rhinosinusitis (CRS), remains poorly understood. | 25975248 |
| Eosinophilic disorder, Inflammation | Altered Intercellular Communication | Interleukin (IL) 25, IL-33, and thymic stromal lymphopoietin (TSLP) are epithelial-derived cytokines implicated in the initiation of T-helper 2 inflammation and eosinophilia in other diseases. | 25975248 |
| Inflammation, Craniosynostosis | Altered Intercellular Communication | The expression of these cytokines was compared with phenotypic and histopathologic markers to investigate the factors that may drive eosinophilic inflammation in CRS. | 25975248 |
| Inflammation | Altered Intercellular Communication | Similar overexpression was seen in eosinophilic dominated inflammation (IL-25, p = 0.01; IL-33, p = 0.02) and patients with greater inflammatory severity. | 25975248 |
| Inflammation, Craniosynostosis | Altered Intercellular Communication | IL-25 and IL-33 overexpression was observed in eosinophilic CRS, The release of these cytokines by dysfunctional endothelium may perpetuate the eosinophillic inflammation in CRS. | 25975248 |
| Granulomatosis, Autoimmune Diseases, Airway structure, Vasculitis, CTCAE, Systemic Vasculitis | Altered Intercellular Communication | Granulomatosis with polyangiitis (GPA) is an autoimmune disease characterized by necrotizing granulomatous airway inflammation and vasculitis. | 25975251 |
| Sepsis, Inflammation | Altered Intercellular Communication | Soluble VE-cadherin is involved in endothelial barrier breakdown in systemic inflammation and sepsis. | 25975259 |
| Joint laxity, CLEFT LIP/PALATE WITH ABNORMAL THUMBS AND MICROCEPHALY, Unknown (origin) (qualifier value), Microspectrophotometry, Chronic musculoskeletal pain | Altered Intercellular Communication | Chronic Musculoskeletal Pain (MSP) in children can be due to non-inflammatory conditions, such as the benign joint hypermobility syndrome (BJHS) or idiopathic MSP (IMSP). | 25976338 |
| Inflammation, hepcidin, Anemia, Chronic Kidney Diseases | Altered Intercellular Communication | To explore the probable association of serum hepcidin and haemoglobin levels with iron and inflammation statuses in patients of chronic kidney disease stage 4 with anaemia. | 25976565 |
| ARCN1 gene, Inflammation | Altered Intercellular Communication | In summary, serum ITIH4 may be a PM10-specific biomarker in COPD and may be related to inflammation. | 25977605 |
| Inflammation | Altered Intercellular Communication | In addition, chronic inflammation produced by Gaucher cells induces the production of several cytokines, which leads to direct changes in the bone remodelling process and can also affect the process indirectly through other immune cells. | 25978039 |
| Inflammation, Electrocardiogram: myocardial infarction (finding), Anemia | Altered Intercellular Communication | Anemia and Inflammation in ST-Segment Elevation Myocardial Infarction. | 25978119 |
| Inflammation, Inflammatory disorder | Altered Intercellular Communication | Immune semaphorins are a large family of proteins involved in the pathogenesis of inflammatory diseases through the regulation of immune homeostasis and tissue inflammation. | 25978359 |
| Inflammation, Ulcerative Colitis, Crohn Disease | Altered Intercellular Communication | We aim to assess the possible involvement of semaphorin3A (sema3A) and 4A (sema4A) in peripheral immune responses and bowel tissue inflammation of patients suffering from Crohn's disease (CD) and ulcerative colitis (UC). | 25978359 |
| Inflammatory Bowel Diseases, Inflammation, Failure (biologic function) | Altered Intercellular Communication | Altered % of Tregs expressing sema3A in patients with inflammatory bowel diseases (IBD) is partially responsible for their failure in preventing CD4+ effector T cell induced inflammation in IBD in peripheral blood. | 25978359 |
| Inflammation, Ulcerative Colitis | Altered Intercellular Communication | The increased expression of sema4A in bowel biopsies from CD and UC patients is suggestive of its central role in regulating local tissue inflammation in the bowel. | 25978359 |
| Inflammation, Hypoxia | Altered Intercellular Communication | Proteins related to hypoxia, angiogenesis, and inflammation were significantly elevated in the vitreous of CRVO patients. | 25978399 |
| Inflammation, Swelling | Altered Intercellular Communication | There was no history of inflammation or swelling of the eyelid. | 25978533 |
| Inflammation, Eales disease, PDR gene, Diabetic Retinopathy, Polypoidal choroidal vasculopathy, Retinal Diseases, Retinal Vein Occlusion | Altered Intercellular Communication | To examine the expression of pro-interleukin-1b (pro-IL-1b) and interleukin-1b (IL-1b) in the vitreous body of patients with neovascular age-related macular degeneration(nAMD), polypoidal choroidal vasculopathy (PCV), proliferative diabetic retinopathy (PDR), retinal vein occlusion (RVO) or Eales' disease to further elucidate the role of IL-1b and inflammation in the pathogenesis of neovascular retinal disease. | 25978536 |
| Crohn Disease, Inflammation, Ulcerative Colitis | Altered Intercellular Communication | New cases of ulcerative colitis (UC) and Crohn's disease (CD) were retrieved by thorough review of all small and large intestinal pathology reports with any type of inflammation from all the pathology departments in Iceland for the period 1995-2009. | 25979112 |
| Eosinophilic disorder, Eosinophilic Granuloma, Inflammation, Systemic Vasculitis | Altered Intercellular Communication | Eosinophilic granulomatosis with polyangiitis (EGPA) is a rare eosinophil-rich disorder characterised by necrotising granulomatous inflammation affecting small to medium sized vessels. | 25979957 |
| Cessation of life, Inflammation, Malnutrition | Altered Intercellular Communication | In Cox analyses, T3 level was a significant predictor of all-cause mortality (per 10-unit increase, adjusted hazard ratio [HR], 0.86; 95% confidence interval [95% CI], 0.78 to 0.94; P=0.002), CV death (per 10-unit increase, adjusted HR, 0.84; 95% CI, 0.75 to 0.98; P=0.01), and sudden death (per 10-unit increase, adjusted HR, 0.69; 95% CI, 0.56 to 0.86; P=0.001) after adjusting for well known risk factors including inflammation and malnutrition. | 25979970 |
| Inflammation, Esophageal diverticulum | Altered Intercellular Communication | Other reasons, such as compression of the tracheal intubation balloon and repeated inflammation of the oesophageal diverticulum, may also have contributed to the recanalisation. | 25980770 |
| Inflammation, Rheumatism | Altered Intercellular Communication | In the case of rheumatic diseases, the synovial joint cavity represents a secluded area of inflammation which could harbor etiological agents. | 25980837 |
| Communicable Diseases, Inflammation | Altered Intercellular Communication | IL-1a plays an important role in inflammation, immunity and defense against infection. | 25981582 |
| Inflammation, Pulmonary Edema, Alveolar Epithelial Cells, Hemorrhage | Altered Intercellular Communication | DAD is characterized by hyaline membrane formation, lung edema, inflammation, hemorrhage and alveolar epithelial cell injury. | 25981598 |
| Pain Distress Question, Knee pain, Depression, CTCAE, Bipolar Disorder | Altered Intercellular Communication | Among the potential contributors, we hypothesized that coexisting depressive symptoms might increase the severity of knee pain because the increased cytokine levels and neurotransmitter changes related to depression are known to influence the threshold of physical pain perception. | 25982621 |
| Inflammation, Electrocardiogram: myocardial infarction (finding) | Altered Intercellular Communication | Acute myocardial infarction activates distinct inflammation and proliferation pathways in circulating monocytes, prior to recruitment, and identified through conserved transcriptional responses in mice and humans. | 25982896 |
| Inflammation | Altered Intercellular Communication | Patterns of gene expression associated with inflammation and proliferation appear to be switched on prior to their infiltration of injured myocardium suggesting that the specific targeting of inflammatory and proliferative processes in these immune cells in humans are possible therapeutic strategies. | 25982896 |
| Inflammation, Gastritis, Myocarditis, CTCAE 5.0, Nephritis | Altered Intercellular Communication | However, the GSH level in erythrocytes from people who had inflammation (myocarditis, nephritis and gastritis) was generally higher than that from the healthy people. | 25983061 |
| Inflammation, Lupus Erythematosus, Systemic | Altered Intercellular Communication | Serum Cyr61 is associated with clinical disease activity and inflammation in patients with systemic lupus erythematosus. | 25984669 |
| Inflammation, Lupus Erythematosus, Systemic | Altered Intercellular Communication | In conclusion, serum Cyr61 was increased in patients with SLE which was associated with clinical disease activity and inflammation in SLE, suggesting Cyr61 may be a novel potential auxiliary marker for the diagnosis of SLE. | 25984669 |
| Inflammatory Bowel Diseases, Gingivitis, Dental Plaque | Altered Intercellular Communication | Children with IBD compared with controls had a statistically significant (P < 0.001) higher dmf-t (2.95 versus 0.91) or DMF-T (5.81 versus 2.04) index and a higher gingival inflammation (simplified gingival, 40% versus 24%) although the respectively dental plaque index showed no significant difference (plaque control record, 42% versus 41%). | 25985243 |
| Airway structure, Bronchial Hyperreactivity | Altered Intercellular Communication | However, an ACT does not include assessment of airway inflammation, which is better reflected when measuring nonspecific bronchial hyperresponsiveness (BHR). | 25985789 |
| Glomerulonephritis, Interstitial inflammation | Altered Intercellular Communication | He had a renal biopsy, which revealed acute immune complex glomerulonephritis with interstitial inflammation. | 25986232 |
| Inflammation | Altered Intercellular Communication | Overall, concordance between endoscopic and histological remission was moderate (k=0.56, 95% CI 0.36 to 0.77); 24% patients had persistent inflammation despite endoscopic remission. | 25986946 |
| Primary malignant neoplasm | Altered Intercellular Communication | Systemic inflammatory response was shown to play an important role in development and progression of many cancer types and different inflammation-based indices were used for determining prognosis. | 25987075 |
| Degenerative polyarthritis, Inflammation | Altered Intercellular Communication | The higher levels of p21 in OA MPCs are also correlated with a decreased chondrogenic differentiation capacity and synovial inflammation, however, there was no evidence of senescence in the OA cells. | 25987237 |
| Hepatitis B Virus-Related Hepatocellular Carcinoma, Inflammation | Altered Intercellular Communication | Inflammation scores predict survival for hepatitis B virus-related hepatocellular carcinoma patients after transarterial chemoembolization. | 25987783 |
| Hepatitis B Virus-Related Hepatocellular Carcinoma, Inflammation, FAM126A gene | Altered Intercellular Communication | To compare the prognostic ability of inflammation scores for patients with hepatitis B virus (HBV)-related hepatocellular carcinoma (HCC) undergoing transarterial chemoembolization (TACE). | 25987783 |
| Inflammation, FAM126A gene | Altered Intercellular Communication | The prognostic ability of GPS is superior to other inflammation scores for HCC patients undergoing TACE. | 25987783 |
| Refractory anemias, Arthralgia, Inflammation | Altered Intercellular Communication | CVD incidence was increased in women with RA versus women with no reported RA at almost all risk factor levels, except for low levels of joint pain or inflammation. | 25988241 |
| Refractory anemias, Inflammation, Choline Dehydrogenase, Mitochondrial | Altered Intercellular Communication | Among women with RA, inflammation was more strongly associated with fatal CVD and total mortality than with CHD or CVD. | 25988241 |
| Arthralgia, Inflammation | Altered Intercellular Communication | CVD risk was strongly associated with CVD risk factors, joint pain severity, and inflammation, but not with anti-CCP positivity or RF positivity. | 25988241 |
| Arterial Stiffness, Inflammation, Rheumatoid Arthritis, Carotid Intima-Media Thickness | Altered Intercellular Communication | There was no correlation between arterial stiffness index and common carotid intima-media thickness with markers of inflammation and disease activity in hypertensive rheumatoid arthritis patients. | 25990366 |
| Inflammation, Fibrosis Assessment | Altered Intercellular Communication | Reduced bacterial colony count of anaerobic bacteria is associated with a worsening in lung clearance index and inflammation in cystic fibrosis. | 25992575 |
| Orthodontic, Inflammation, Dental Plaque | Altered Intercellular Communication | Alterations in plaque accumulation and gingival inflammation promoted by treatment with self-ligating and conventional orthodontic brackets. | 25992985 |
| Chronic inflammation | Altered Intercellular Communication | However, here we hypothesized that a tonsillolith can also be formed by chronic saliva stasis in the tonsillar tissue, without any signs of chronic inflammation. | 25993312 |
| Inflammation, Obesity | Altered Intercellular Communication | Activation of adipose tissue inflammation is associated with obesity caused by lipid accumulation in adipocytes. | 25993353 |
| Inflammation, Carcinogenesis | Altered Intercellular Communication | In addition to its role as a transport protein, the vitamin D binding protein (DBP) may also affect lipid metabolism, inflammation and carcinogenesis. | 25993554 |
| ARCN1 gene, Inflammation | Altered Intercellular Communication | COPD is a progressive disease of the airways that is characterized by neutrophilic inflammation, a condition known to promote the excessive formation of neutrophil extracellular traps (NETs). | 25994149 |
| Inflammation, Diabetes Mellitus | Altered Intercellular Communication | Type-2 diabetes is associated with systemic inflammation and higher C-reactive protein (CRP) levels. | 25994228 |
| Inflammation, Diabetes Mellitus, Cardiovascular Diseases | Altered Intercellular Communication | Understanding such associations may shed light on the role of inflammation in development of type-2 diabetes and its complications such as cardiovascular diseases. | 25994228 |
| Inflammation, Diabetes Mellitus | Altered Intercellular Communication | In this study we found longitudinal observational evidence suggesting that increase in systemic inflammation is associated with an increase in HbA1c and thus systemic inflammation may have a role in development of type-2 diabetes and its complications. | 25994228 |
| Inflammation, Chronic Kidney Diseases | Altered Intercellular Communication | Monocyte-to-HDL ratio (M/H ratio) is a recently emerged indicator of inflammation and oxidative stress which have been only studied in patients with chronic kidney disease. | 25995388 |
| Inflammation | Altered Intercellular Communication | A 58-year-old woman presented painful chronic inflammation of the outside skin of the bilateral soles. | 25997079 |
| Inflammation, Stanford Cancer Institute | Altered Intercellular Communication | ](Ct)) method in subclinical inflammation (SCI, n=10), clinical inflammation in acute T-cell mediated rejection (CI, n=10) and no rejection samples (n=9). | 25997515 |
| Inflammation, PTAFR gene | Altered Intercellular Communication | Clinical inflammation group showed a increased expression of genes for chemotaxis mediating cytokines (CCL1, CCL17, CCL24, CCL25, CCL26), cytokine receptors (CCR1, CCRL2, IL1RAPL2, CXCR5), proinflammatory cytokines (IL12A, LTA), inflammatory mediator (PTAFR), complement protein C3, executioner protein of apoptosis (CASP7), growth factor (TGFA), colony stimulating factor (CSF-2), proteins involved in dendritic cells differentiation and interaction (CD209, LAMP3), regulation of immune response (LILRB2, LILBRB4). | 25997515 |
| Nephritis | Altered Intercellular Communication | Subclinical acute kidney inflammation has transcriptional profile of immune injury of lower extend compared to clinical acute inflammation. | 25997515 |
| Symptoms, Inflammation | Altered Intercellular Communication | Child maltreatment, inflammation, and internalizing symptoms: Investigating the roles of C-reactive protein, gene variation, and neuroendocrine regulation. | 25997771 |
| Symptoms, Inflammation | Altered Intercellular Communication | Our findings highlight the importance of the timing of child maltreatment and have important implications for characterizing variability in inflammation and internalizing symptoms among youth. | 25997771 |
| ARCN1 gene, Chronic inflammation, airway disease, Chronic Obstructive Airway Disease, Asthma | Altered Intercellular Communication | Obstructive airway diseases, such as asthma and chronic obstructive pulmonary disease (COPD), have airflow limitation associated with chronic inflammation. | 25998444 |
| Inflammatory Bowel Diseases, Inflammation | Altered Intercellular Communication | Abnormal levels of microRNA (miR)-155, which regulate inflammation and immune responses, have been demonstrated in the colonic mucosa of patients with inflammatory bowel diseases (IBD), although its role in disease pathophysiology is unknown. | 25998827 |
| Renal Insufficiency, Inflammation, Anemia, hepcidin | Altered Intercellular Communication | In the absence of overt renal impairment, anemia in T2DM is associated with chronic inflammation, inducing elevation of hepcidin and GDF15 levels independently of the erythropoietin level. | 25998917 |
| Inflammation, Endothelial dysfunction, Atherosclerosis | Altered Intercellular Communication | Cigarette smoking is a major risk factor in the progression of atherosclerosis and has been shown to cause endothelial dysfunction, inflammation, and modification of lipid profile. | 25999135 |
| Inflammation, Primary malignant neoplasm | Altered Intercellular Communication | Improved insulin sensitivity and reduced inflammation are among the hypothesized mechanisms by which coffee drinking may affect cancer risk; however, associations between coffee drinking and systemic levels of immune and inflammatory markers have not been well characterized. | 25999212 |
| Inflammation, diabetic | Altered Intercellular Communication | Is vitamin D deficiency related to accumulation of advanced glycation end products, markers of inflammation, and oxidative stress in diabetic subjects? | 26000307 |
| Inflammation, Primary malignant neoplasm, Atherosclerosis | Altered Intercellular Communication | Our current understanding of the patholobiology of these fundamental disorders suggests that inflammatory processes may differentially affect them; thus, atherosclerosis can be largely driven by inflammation, where as cancer often flourishes as inflammatory responses are modulated. | 26000958 |
| Neoplasms | Altered Intercellular Communication | Furthermore, this correlation is not uniformly associated with anti-neoplastic treatment, suggesting that the inverse relationship may be in part attributable to an individual's intrinsic inflammatory propensity, and/or to inflammation-modulatory properties of neoplasms. | 26000958 |
| Refractory anemias, Inflammation | Altered Intercellular Communication | These results suggest that thrombin can exacerbate inflammation in RA by impairing the MPO inhibitory function of CP via proteolysis and by competitively inhibiting CP ferroxidase activity. | 26001728 |
| Inflammation, Necrosis of retina, Retinal Vasculitis, Vitreous body structure | Altered Intercellular Communication | Progressive outer retinal necrosis is characterized clinically as showing minimal or no inflammation in the aqueous and vitreous humors, absence of retinal vasculitis, and patches of yellowish spots located deep in the retina. | 26002429 |
| Inflammation, Liver Cirrhosis | Altered Intercellular Communication | The protein related with this gene is accumulated within the endoplasmic reticulum of hepatocytes causing their damage, inflammation and cirrhosis. | 26003074 |
| Infection, Helicobacter Infections | Altered Intercellular Communication | Rare Helicobacter pylori organisms accounted for 58.0% of all atypical infections; the next most common atypical Helicobacter infection was that with minimal or no gastric inflammation (23.3% of atypical infections). | 26003395 |
| Inflammation, Pain Distress Question, Necrosis, Edema, Hypertrophy | Altered Intercellular Communication | Histologically, hypertrophy and inflammation of the tendon and hypertrophy, inflammation, oedema and necrosis of the subacromial bursa were directly associated with pain (P < 0.05). | 26003482 |
| Asthma, IL13 gene | Altered Intercellular Communication | Accumulating evidence is indicating that hormonal factors play a role in new-onset allergic rhinitis and asthma after puberty. | 26003905 |
| Osteolysis | Altered Intercellular Communication | The pharmacological targeting of ER-stress-mediated inflammatory signaling pathways might be an appealing approach for alleviating or preventing particle-induced osteolysis in at-risk patients. | 26004143 |
| Airway structure, Chronic Obstructive Airway Disease | Altered Intercellular Communication | Patients with chronic obstructive pulmonary disease and chronically colonized with Haemophilus influenzae during stable disease phase have increased airway inflammation. | 26005341 |
| ARCN1 gene, Chronic Obstructive Airway Disease, Airway structure, Colonization | Altered Intercellular Communication | Some patients with chronic obstructive pulmonary disease (COPD) show increased airway inflammation and bacterial colonization during stable phase. | 26005341 |
| Airway structure | Altered Intercellular Communication | The difference in airway inflammation seen during stable phase in patients chronically colonized with H. influenzae was not observed during exacerbations. | 26005341 |
| ARCN1 gene, Airway structure | Altered Intercellular Communication | Some COPD patients who were chronically colonized with H. influenzae during stable phase showed increased airway inflammation and reduced lung volumes when compared with non-chronically colonized patients. | 26005341 |
| Myocarditis | Altered Intercellular Communication | Imaging of myocardial inflammation with somatostatin receptor based PET/CT - A comparison to cardiac MRI. | 26005805 |
| Myocarditis, CTCAE 5.0, Myocarditis | Altered Intercellular Communication | Acute myocarditis as well as post-ischemic myocardial inflammation are generally associated with a profound activation of the immune system. | 26005805 |
| Sepsis, Inflammation | Altered Intercellular Communication | Matrix metalloproteinases (MMPs)-8 and -9 are released from neutrophils and activated in sepsis to participate in inflammation in several ways. | 26008138 |
| Inflammation, Primary malignant neoplasm | Altered Intercellular Communication | Cluster of differentiation 93 (CD93) is involved in apoptosis and inflammation and has a suggested role in angiogenesis, and all of which are involved in the development and dissemination of cancer. | 26008729 |
| One Vessel Coronary Disease, Inflammation, Atherosclerosis | Altered Intercellular Communication | Background Various pathophysiological mechanisms such as microvascular and endothelial dysfunction, small vessel disease, diffuse atherosclerosis, and inflammation have been held responsible in the etiology of coronary slow flow. | 26008865 |
| Acute and chronic inflammation | Altered Intercellular Communication | On recent admission, blood tests, endoscopies and CT scans indicated chronic colonic inflammation. | 26009604 |
| Inflammation | Altered Intercellular Communication | Treatment strategies for bowel inflammation were unsuccessful and the patient was subsequently discussed at a multidisciplinary team meeting with surgeons for consideration of colectomy. | 26009604 |
| Inflammation, Diarrhea, Peptic Ulcer | Altered Intercellular Communication | It is important that clinicians are aware of the link between pharmacotherapy, specifically nicorandil and gastrointestinal ulceration and inflammation causing severe diarrhoea. | 26009604 |
| Respiratory Distress Syndrome, Adult, Inflammation | Altered Intercellular Communication | The results suggest that the peak in plasma MMP-9 activity may precede the peak of neutrophil inflammation in the airways and lung tissue in the setting of ARDS. | 26009816 |
| Traumatic injury | Altered Intercellular Communication | Impact of Injury Severity on Dynamic Inflammation Networks Following Blunt Trauma. | 26009819 |
| Inflammation, Nonpenetrating Wounds | Altered Intercellular Communication | We hypothesized that dynamic networks of systemic inflammation manifest differently as a function of injury severity in human blunt trauma. | 26009819 |
| Inflammation, Superficial ulcer | Altered Intercellular Communication | Based on clinical observation, inflammatory markers, and radiographic reports, in the follow-up visits, they remain with no signs of inflammation and no new erosions on radiograph. | 26010182 |
| Inflammation, Asthma | Altered Intercellular Communication | Secondary outcome measures were symptoms, episodes of poor asthma control, Asthma Control Test score (range, 5-25; higher scores indicate better control), and systemic and airway biomarkers of inflammation. | 26010632 |
| Delirium, Inflammation, Critical Illness | Altered Intercellular Communication | We investigated whether exposure to medication with anticholinergic properties increases the probability of transitioning to delirium in critically ill adults and whether this relationship is affected by age or the presence of acute systemic inflammation. | 26010688 |
| Inflammation, Cardiac complication, Hemodynamic instability | Altered Intercellular Communication | Patients with SCM and systemic inflammation with hemodynamic instability might be susceptible to TAWT, which is often associated with cardiac complications. | 26011273 |
| Hyperlipidemia | Altered Intercellular Communication | Evidence in obese children: contribution of hyperlipidemia, obesity-inflammation, and insulin sensitivity. | 26011530 |
| Inflammation, Dyslipidemias, Obesity | Altered Intercellular Communication | Evidence shows a high incidence of insulin resistance, inflammation and dyslipidemia in adult obesity. | 26011530 |
| Inflammation, Overweight | Altered Intercellular Communication | The overweight subjects only exhibited significant insulin resistance and low-grade inflammation. | 26011530 |
| palladium, Inflammation, Acute peritonitis, Peritonitis | Altered Intercellular Communication | We enrolled 53 PD patients: 30 without any history of systemic inflammation or peritonitis in the last 3 months (group A) and 23 with acute peritonitis (group B). | 26012380 |
| Inflammation, Osteopenia, Peri-Implantitis | Altered Intercellular Communication | Eighteen individuals diagnosed with peri-implantitis (clinical signs of inflammation and progressive bone loss) on at least two implants were included. | 26013241 |
| Inflammation, Bipolar Disorder | Altered Intercellular Communication | The association between depressive traits and CVD may be moderated by low-grade inflammation. | 26013320 |
| Inflammation, Fibrosis Assessment, Thrombosis | Altered Intercellular Communication | However, the inflammation also leads to progressive fibrosis and occlusion of the veins without thrombosis. | 26013364 |
| Inflammation, Calcinosis | Altered Intercellular Communication | Significant correlations were found between prostatic calcification and the severity of inflammation (P<0.02) as well as the NIH-CPSI subdomain of urinary symptoms (P<0.02). | 26013949 |
| Inflammation, Obesity | Altered Intercellular Communication | The inverse association of carotenoids with obesity measures may reflect reduced micronutrient concentrations owing to inflammation associated with obesity. | 26014267 |
| Sunburn, Skin Carcinogenesis, Inflammation | Altered Intercellular Communication | Increasing evidence has identified ultraviolet radiation (UVR) as the skins most potent mutagen as over exposure results in sunburn, inflammation and DNA damage, thus contributing to a photo-ageing phenotype and possibly skin carcinogenesis. | 26014614 |
| Inflammation, Obesity | Altered Intercellular Communication | Obesity was associated with systemic inflammation, greater leg fat mass, and patterns of mRNA expression consistent with muscle deconditioning, whereas leg lean mass, strength, and work done during maximal exercise were no different. | 26015550 |
| Tendinitis | Altered Intercellular Communication | This tendinitis may also occur in patients with systemic inflammatory conditions and is classified as posterior tibial tendon dysfunction stage I. | 26016290 |
| Inflammation, Cerebrovascular accident | Altered Intercellular Communication | Stroke patients had lower HDL-cholesterol than controls and a remarkable fall in PON1 activity (control group-227U/L, survivors-42U/L, lethal outcome group-61U/L, p < 0.001), along with more prominent inflammation. | 26016451 |
| Inflammation, Arteritis | Altered Intercellular Communication | Regulation of Inflammation and Angiogenesis in Giant Cell Arteritis by Acute-Phase Serum Amyloid A. | 26016600 |
| Inflammation, vascular inflammations, Atherosclerosis | Altered Intercellular Communication | Acute-phase serum amyloid A (A-SAA) is an acute-phase reactant, but is also produced at sites of inflammation and may contribute to vascular inflammation in atherosclerosis. | 26016600 |
| Arteritis | Altered Intercellular Communication | Our findings demonstrate a functional role for A-SAA in regulating temporal artery inflammation, angiogenesis, and invasion, all key processes in the pathogenesis of GCA. | 26016600 |
| ARCN1 gene, Inflammation, Endothelial dysfunction | Altered Intercellular Communication | Preliminary studies have shown that both airflow obstruction and systemic inflammation may contribute to endothelial dysfunction in COPD. | 26016823 |
| Inflammation, Kidney Diseases | Altered Intercellular Communication | Serum retinol--a VAD marker--increases in kidney disease and decreases in inflammation, which can partly be attributed to alterations in the vitamin A-transport proteins retinol-binding protein 4 (RBP4) and prealbumin. | 26016862 |
| Abnormal renal function, Inflammation, Hypertension, CTCAE, Diabetes Mellitus, Non-Insulin-Dependent | Altered Intercellular Communication | Kidney dysfunction and inflammation commonly accompany T2D and hypertension. | 26016862 |
| Inflammation, Hypertension, CTCAE, Diabetes Mellitus, Non-Insulin-Dependent | Altered Intercellular Communication | Among urban Ghanaians, we investigated the associations of T2D and hypertension with serum retinol as well as the importance of kidney function and inflammation in this regard. | 26016862 |
| Intraocular inflammation, Abscess | Altered Intercellular Communication | He received an empirical antibiotic and antiviral agent intravenously followed by oral prednisolone until the etiology was identified; however, intraocular inflammation in the left eye continued to worsen, followed by the development of subretinal abscess in the contralateral eye. | 26017191 |
| Inflammation, Respiratory Tract Infections, Equilibration disorder | Altered Intercellular Communication | The onset of the balance disorder was preceded by respiratory infection: common cold with symptoms of inflammation of the mucous membrane in the nose and throat. | 26017723 |
| Inflammation, hafnium | Altered Intercellular Communication | We hypothesized that mitochondrial respiratory dysfunctions of peripheral blood mononuclear cells (PBMCs) may be associated with inflammation and oxidative stress in early-stage HF patients complicated with cardiometabolic risk factors. | 26018291 |
| Inflammation, Congenital Heart Defects, hafnium | Altered Intercellular Communication | It showed that excessive inflammation and reduced antioxidant capacity were closely associated with cardiac abnormalities in early-stage HF patients. | 26018291 |
| Inflammation, Disturbance | Altered Intercellular Communication | Our study indicated that cardiometabolic risk factor-mediated mitochondrial respiratory dysfunctions of PBMCs link with the cellular inflammation / oxidative stress and cardiac disturbance in early-stage HF. | 26018291 |
| Inflammation, Prostate carcinoma | Altered Intercellular Communication | A guided biopsy by ultrasonography was performed revealing a prostate carcinoma and inflammation in both prostatic lobes. | 26018697 |
| Renal Insufficiency, Inflammation | Altered Intercellular Communication | Our results demonstrate a stage-dependent plasma Ab increase that is augmented by loss of glomerulotubular integrity, low body weight, and inflammation, demonstrating a multifaceted role of renal dysfunction in Ab retention. | 26019016 |
| Allergic, Acute and chronic inflammation | Altered Intercellular Communication | The integrity of the epithelial layer in the gastrointestinal tract protects organisms from exposure to luminal antigens, which are considered the primary cause of chronic intestinal inflammation and allergic responses. | 26019243 |
| Inflammation, Colitis | Altered Intercellular Communication | Our findings support the hypothesis that a luminal factor triggers the inflammation observed in collagenous colitis. | 26019474 |
| Lymphadenopathy | Altered Intercellular Communication | The Kimura disease is a benign rare inflammatory condition of the soft tissue, especially of the head and neck region presenting as painless nodule with or without lymphadenopathy. | 26020715 |
| Inflammation, Gastrointestinal mucositis, Peri-Implantitis | Altered Intercellular Communication | A controlled, cross-sectional exploratory study on markers for the plasminogen system and inflammation in crevicular fluid samples from healthy, mucositis and peri-implantitis sites. | 26021226 |
| Inflammation, Gastrointestinal mucositis, Peri-Implantitis | Altered Intercellular Communication | Markers for the plasminogen system and inflammation could be used to distinguish between mucositis and peri-implantitis. | 26021226 |
| Inflammation, Gastrointestinal mucositis, Peri-Implantitis | Altered Intercellular Communication | The results suggested that the plasminogen system was sufficiently upregulated allowing for resolution of inflammation and healing at the inflamed implant site in subjects with mucositis, whereas such upregulation was insufficient resulting in impaired healing and prolonged inflammation in subjects with peri-implantitis. | 26021226 |
| Inflammation, Osteopenia | Altered Intercellular Communication | The combination of tissue inflammation and low levels of tPA was a strong predictor of marginal bone loss in this study. | 26021226 |
| Inflammation | Altered Intercellular Communication | This case demonstrates that masses in the craniocervical junction can be varied in pathology and when there is evidence of systemic inflammation, HP should be considered. | 26021381 |
| Fibrosis Assessment, Thickened | Altered Intercellular Communication | Histology showed densely collagenous tissue with scanty psammoma bodies and multinucleate giant cells, consistent with hypertrophic pachymeningitis (HP)-a rare, chronic inflammatory condition, characterised by thickening and fibrosis of the dura. | 26021381 |
| Granulomatosis, Inflammation, Vasculitis, CTCAE, Systemic Vasculitis | Altered Intercellular Communication | Granulomatosis with polyangiitis (GPA) is a systemic necrotizing vasculitis, associated with antineutrophil cytoplasmic autoantibody-associated systemic vasculitis, and it can affect many organ systems via the inflammation of small-to-medium-sized vessels. | 26021454 |
| Atrial Fibrillation, Inflammation, Atrial Fibrillation by ECG Finding | Altered Intercellular Communication | Current evidence links atrial fibrillation (AF) to the inflammation. | 26021499 |
| Inflammation | Altered Intercellular Communication | However, the role of inflammation in the atrial electrophysiological remodeling indexed by P-wave dispersion (P d ) remains unclear. | 26021499 |
| Inflammation | Altered Intercellular Communication | The interaction between hs-CRP and AF may be mediated by P d , suggesting an important role of inflammation in the atrial electrophysiological remodeling predisposing to AF. | 26021499 |
| Orchitis, Malignant Neoplasms | Altered Intercellular Communication | Currently, 64-slice multidetector CT scanners are capable of providing higher-resolution images and may be able to distinguish malignancy from diverticular inflammation. | 26022155 |
| Inflammation, COL4A2 wt Allele, Cerebral Hemorrhage | Altered Intercellular Communication | Inflammation may provoke cerebral arteriolar ectasia, inducing microaneurysm formation and further promoting intracerebral hemorrhage (ICH). | 26024006 |
| Sepsis, Inflammation | Altered Intercellular Communication | Peptide 19-2.5 inhibits heparan sulfate-triggered inflammation in murine cardiomyocytes stimulated with human sepsis serum. | 26024383 |
| Sepsis, Inflammation, Myocardial dysfunction | Altered Intercellular Communication | Myocardial dysfunction in sepsis has been linked to inflammation caused by pathogen-associated molecular patterns (PAMPs) as well as by host danger-associated molecular patterns (DAMPs). | 26024383 |
| Myocarditis | Altered Intercellular Communication | Based on these findings, peptide 19-2.5 is a novel anti-inflammatory agent interacting with both PAMPs and DAMPs, suggesting peptide 19-2.5 may have the potential for further development as a broad-spectrum anti-inflammatory agent in sepsis-induced myocardial inflammation and dysfunction. | 26024383 |
| Inflammation, Fibrosis Assessment, Hepatitis B | Altered Intercellular Communication | Chronic Hepatitis B Virus Infection: The Relation between Hepatitis B Antigen Expression, Telomere Length, Senescence, Inflammation and Fibrosis. | 26024529 |
| Inflammation, Fibrosis Assessment | Altered Intercellular Communication | We also investigated the relation between inflammation, fibrosis and cell cycle phase. | 26024529 |
| Granulomatosis, Inflammation, Systemic Vasculitis, Atherosclerosis | Altered Intercellular Communication | The interface of inflammation and subclinical atherosclerosis in granulomatosis with polyangiitis (Wegener's): a preliminary study. | 26024800 |
| Inflammation, Atherosclerosis | Altered Intercellular Communication | The cumulative burden of systemic inflammation in GPA correlated with the development of subclinical atherosclerosis. | 26024800 |
| Inflammation, Mucopolysaccharidosis I, Atherosclerosis | Altered Intercellular Communication | The findings of increased levels of circulating leukocyte-derived MPs and enhanced platelet reactivity during relapse suggest possible roles for MPs and platelets in disease pathogenesis and support a growing literature that links inflammation, atherosclerosis, and platelet activation. | 26024800 |
| Inflammation | Altered Intercellular Communication | No significant difference regarding anterior chamber inflammation and discomfort was observed between the 3 groups. | 26025033 |
| Intraocular inflammation | Altered Intercellular Communication | There was no difference in intraocular pressure reduction, intraocular inflammation or ocular discomfort post-SLT when comparing the 3 treatment modalities. | 26025033 |
| Sepsis, Inflammation | Altered Intercellular Communication | Sepsis is a lethal outcome of the inflammation and coagulation process. | 26025100 |
| Sepsis, Tumor necrosis, Inflammation | Altered Intercellular Communication | Human interleukin (IL)-6 and tumor necrosis factor (TNF) a are well-known inflammation factors closely associated with sepsis. | 26025100 |
| Inflammation, Ototoxicity | Altered Intercellular Communication | During inflammation, the kynurenine pathway (KP) metabolises the essential amino acid tryptophan (TRP) potentially contributing to excitotoxicity via the release of quinolinic acid (QUIN) and 3-hydroxykynurenine (3HK). | 26025142 |
| Inflammation, Fibrosis Assessment, Bronchioles, Pneumonia, Interstitial | Altered Intercellular Communication | Almost 60% of UIP/IPF explants showed NSIP areas and 41% peribronchiolar fibrosis; inflammation, bronchiolar metaplasia, and vascular changes were more frequent in UIP/IPF explants; and Desquamative Interstitial Pneumonia (DIP)-like areas were not common (18%-27%). | 26025258 |
| Cholecystitis | Altered Intercellular Communication | This was verified in an in vivo model using a pathogenic E. coli isolated from one of the patients in guinea pigs and observed marked gallbladder inflammation and morphologic changes. | 26025761 |
| Pain Distress Question, Inflammation | Altered Intercellular Communication | Pain scores were higher at the laparoscopic port incision sites than in upper abdominal sites distant from incisions or expected inflammation, mean (SD) 3.3 (2.3) and 1.1 (1.8), respectively (p < .0001). | 26025797 |
| Inflammation | Altered Intercellular Communication | Pouch Inflammation Is Associated With a Decrease in Specific Bacterial Taxa. | 26026389 |
| Inflammation, Crohn Disease | Altered Intercellular Communication | Because the inflammation occurs in a previously normal small bowel, studies of this process might provide information about the development of Crohn's disease. | 26026389 |
| Inflammation | Altered Intercellular Communication | Patients were assigned to groups based on their degree and type of pouch inflammation. | 26026389 |
| Inflammation, Ulcerative Colitis | Altered Intercellular Communication | Reductions in protective bacteria and increases in inflammatory bacteria are associated with pouch inflammation in patients with UC who underwent pouch surgery. | 26026389 |
| Inflammation, Carcinogenesis, Colorectal Carcinoma | Altered Intercellular Communication | Patients with colorectal cancer (CRC) have high circulating levels of macrophage inhibitory cytokine-1 (MIC1 or growth differentiation factor 15), a marker of inflammation that might be involved in carcinogenesis. | 26026393 |
| malignant disease, Inflammation | Altered Intercellular Communication | Mast cells play an important role in inflammation and angiogenesis in malignant diseases. | 26026586 |
| Inflammation, Chronic disease | Altered Intercellular Communication | Inflammation increases the risk of chronic diseases, but the links between emotional responses to daily events and inflammation are unknown. | 26030309 |
| Inflammation | Altered Intercellular Communication | Women who experience increased negative affect when faced with minor stressors may be at particular risk of elevated inflammation. | 26030309 |
| Adrenocorticotropic hormone (ACTH) deficiency (disorder) | Altered Intercellular Communication | Hormonal investigations showed partial corticotropic and thyrotropic deficiencies. | 26030326 |
| Inflammation | Altered Intercellular Communication | Activin A, a member of the TGF-b superfamily, plays an important role in inflammation and remodeling in the lower airways, although its expression and release in the upper airways remain undescribed. | 26030615 |
| Inflammation, Malnutrition, Restless Legs Syndrome | Altered Intercellular Communication | Relationships Between Malnutrition, Inflammation, Sleep Quality, and Restless Legs Syndrome in Hemodialysis Patients. | 26031339 |
| Kidney Diseases | Altered Intercellular Communication | Temporal serum creatinine increase and exacerbation of tubulointerstitial inflammation during the first two months in resolving polyomavirus BK nephropathy. | 26031586 |
| Inflammation, Primary Graft Dysfunction | Altered Intercellular Communication | Temporal graft dysfunction and increased inflammation, called immune reconstitution, were observed at 2 months. | 26031586 |
| Vasculitis, Endarteritis, Glomerulitis (disorder), Peritubular Capillaritis Assessment | Altered Intercellular Communication | Microvascular inflammation, such as glomerulitis, peritubular capillaritis, and arteriole endarteritis were also detected. | 26031589 |
| Inflammation | Altered Intercellular Communication | A 1-hour protocol biopsy revealed C4d-positivity and mild peritubular capillary inflammation. | 26031595 |
| Glomerulitis (disorder), GPR182 gene, Inflammation | Altered Intercellular Communication | A second graft biopsy was performed, which showed overt AMR with glomerulitis, peritubular capillary inflammation and no C4d deposition. | 26031595 |
| Inflammation, Atherosclerosis, Cardiovascular Diseases | Altered Intercellular Communication | Angiogenesis and chronic inflammation are known to be co-dependent in atherosclerosis and cardiovascular diseases. | 26032258 |
| Inflammation, Neoplasm Metastasis, Neoplasms | Altered Intercellular Communication | Inflammation plays a crucial role in tumor growth, metastasis, and survival. | 26032829 |
| Communicable Diseases, Inflammation, Intoxication | Altered Intercellular Communication | In patients who exhibit signs of inflammation or infection with increased C-reactive protein values during psychopharmacological treatment, especially under clozapine and risperidone, therapeutic drug monitoring is recommendable in order to minimize the risk of intoxications due to elevated drug concentrations. | 26032842 |
| Respiratory Distress Syndrome, Adult, Inflammation, Endothelium | Altered Intercellular Communication | In the multicenter study, patients with direct ARDS also had lower levels of von Willebrand factor antigen and IL-6 and IL-8, markers of endothelial injury and inflammation, respectively. | 26033126 |
| Nonalcoholic Steatohepatitis, Inflammation, Cholangitis | Altered Intercellular Communication | Two cases did not fit into the above 2 histologic groups: 1 showed portal inflammation with cholangitis, and the other showed morphologic features indistinguishable from nonalcoholic steatohepatitis. | 26034866 |
| Inflammation, Fracture | Altered Intercellular Communication | Polymorphisms in inflammation associated genes ALOX15 and IL-6 are associated with bone properties in young women and fracture in elderly. | 26036173 |
| Inflammation, Fracture | Altered Intercellular Communication | This study suggests that variation in inflammation related genes ALOX15 and IL6 was associated with bone microarchitecture and density in young adult women, but appears to be less important in the elderly, despite an observed association with CRP as a marker of inflammation and incident fracture. | 26036173 |
| Inflammation, Fibromyalgia, Endothelial dysfunction | Altered Intercellular Communication | Recent evidence suggests that fibromyalgia syndrome (FS) is associated with inflammation and endothelial dysfunction. | 26036530 |
| Sandawe language, Inflammation, Cardiovascular Diseases | Altered Intercellular Communication | Considering the significant association of visceral fat with inflammation and cardiovascular disease, estimating visceral fat by means of SAD could be a useful tool to stratify cardiovascular risk as well as graft function in renal transplant recipients. | 26036544 |
| Pancreatic Trypsin Secretory Inhibitor, Kazal, Carcinogenesis, Inflammation | Altered Intercellular Communication | Serine protease inhibitor Kazal type-1 (SPINK1), a trypsin kinase inhibitor, is involved in inflammation, cell proliferation and carcinogenesis. | 26037168 |
| Inflammation, Arterial calcification, Chronic Kidney Diseases | Altered Intercellular Communication | The objective of the study was to determine the relationship between common carotid artery intima-media thickness (CCA-IMT) and histologically assessed calcification of radial artery in relation to clinical features and laboratory markers of bone and mineral metabolism, inflammation, and oxidative stress in patients with stage 5 chronic kidney disease (CKD). | 26037625 |
| Traumatic injury | Altered Intercellular Communication | Imaging data were recorded for eight examinations: head (trauma, shunt), temporal bone, paranasal sinuses, chest (mass) and chest HRCT (high-resolution CT), and abdomen/pelvis (mass/inflammation). | 26037714 |
| Gastritis | Altered Intercellular Communication | The carriage of the C allele of IL-6 may lead a susceptibility to chronic gastric inflammation after contamination with H. pylori. | 26039006 |
| Inflammation, Fracture, Neoplasms | Altered Intercellular Communication | Axial, multiplanar, and 3D-volume-rendered images were reviewed by 3 reviewers for the property of the lesions (fracture, tumor, and tumor-like lesions or inflammation). | 26039118 |
| Inflammation | Altered Intercellular Communication | For the diagnosis of inflammation lesions, average accuracy was 100% for all the 3 image formats. | 26039118 |
| Inflammation, Fracture, Neoplasms | Altered Intercellular Communication | Interobserver agreement independence of imaging formats was high.Multiplanar and 3D-volume-rendered images were superior to axial images in diagnosis of fracture, tumor, and tumor-like lesions; however, for the evaluation of inflammation lesions, there were no difference by 3 image formats. | 26039118 |
| Inflammation, Endothelium | Altered Intercellular Communication | Valvular calcification occurs via ongoing endothelial injury associated with inflammation. | 26039365 |
| ARCN1 gene, Inflammation | Altered Intercellular Communication | IL-17A is central for neutrophilic inflammation and has been linked to COPD pathogenesis. | 26039632 |
| Injury of liver, Inflammation, Liver damage, Hepatitis | Altered Intercellular Communication | IL-1a may have important role as marker of both inflammation and hepatic injury, particularly in the course of hepatitis C. Results suggest that inflammatory and immune parameters, analyzed together can significantly contribute to the understanding and predicting of chronic liver damage. | 26040073 |
| Inflammation, Depression, CTCAE | Altered Intercellular Communication | Inflammation and cell-mediated immune activation are attributed to the pathogenesis and pathophysiology in depression. | 26041659 |
| Inflammation, Depression, CTCAE | Altered Intercellular Communication | This indicated that the elevated neopterin levels may play a significant role in the pathology of depression and that the pathways leading to inflammation and cell-mediated immune activation warrant further exploration. | 26041659 |
| Inflammation, Atherosclerosis | Altered Intercellular Communication | These are key participants in the leukocyte adhesion and transmigration that play a major role in the inflammation and pathophysiology of CVD, including atherosclerosis. | 26042828 |
| Dehydration, Atherosclerosis | Altered Intercellular Communication | Elevated sodium and dehydration stimulate inflammatory signaling in endothelial cells and promote atherosclerosis. | 26042828 |
| Inflammation, Intradermal Route of Drug Administration | Altered Intercellular Communication | Inflammation, but not neurohormonal activation is associated with ID in systolic HF. | 26043148 |
| Ear Inflammation, Acute inflammation, Perforation (observation), Otitis Media with Effusion | Altered Intercellular Communication | Otitis media with effusion (OME) is characterized by the prolonged presence of fluid (longer than 12 weeks) of different viscosity in the middle ear, without perforation of the eardrum or signs of acute inflammation. | 26043589 |
| Inflammation, Atherosclerosis | Altered Intercellular Communication | Finally, LEx were not associated with aging, atherogenic risk factors, atherosclerosis, inflammation, or thrombogenesis. | 26044080 |
| Inflammation | Altered Intercellular Communication | Systemic inflammation appears to be an important contributor to the diseased microvascular network of these patients. | 26044235 |
| Intestinal metaplasia, Inflammation | Altered Intercellular Communication | Helicobacter pylori (n = 154 vs 325, P < 0.001), neutrophil activity (n = 176 vs 367, P < 0.001), intestinal metaplasia (n = 35 vs 14, P < 0.001) and inflammation (n = 230 vs 386, P < 0.001) were present significantly more often in group II compared with group I. | 26044795 |
| Inflammation, Chronic venous insufficiency | Altered Intercellular Communication | Sulodexide suppresses inflammation in patients with chronic venous insufficiency. | 26044841 |
| Inflammation, Central visual impairment, Tissue injury, Venous Insufficiency | Altered Intercellular Communication | According to previously performed studies, inflammation plays a crucial role in vein wall and leg tissue injury related to chronic venous insufficiency (CVI) development. | 26044841 |
| Inflammation, Chronic Obstructive Airway Disease, Pathology | Altered Intercellular Communication | Data identify novel molecular targets for therapeutic strategies aimed at dampening inflammation in pathologies such as chronic obstructive pulmonary disease, in which reduced intracellular HDAC2 levels have been described. | 26044852 |
| HD Term Type, Inflammation | Altered Intercellular Communication | Systemic inflammation is highly prevalent in HD patients and is associated with ESA hyporesponsiveness. | 26045064 |
| HD Term Type, Inflammation | Altered Intercellular Communication | Further research is needed to test whether interventions that successfully decrease oxidative stress and inflammation in patients undergoing maintenance HD improve ESA responsiveness. | 26045064 |
| Inflammation, FAM126A gene | Altered Intercellular Communication | The dlDNA proportion can be regulated by inflammatory cytokines, suggesting an association among inflammation, increased production of HBV dlDNA and development of HCC. | 26045139 |
| Inflammation, Vitreous inflammatory cells | Altered Intercellular Communication | Both anterior segments were without inflammation, but fundoscopy showed mild vitreous inflammation and multiple inflammatory choroidal lesions. | 26045521 |
| Pain Distress Question, prostatitis | Altered Intercellular Communication | CD-163 correlated with symptoms (pain or discomfort) of prostatic inflammation. | 26045748 |
| prostatitis | Altered Intercellular Communication | The purpose of this study is to identify significant immune-system related for symptom of patients with prostatic inflammation in order to investigate the etiology of prostatic inflammation which may relate to potentially chronic prostatitis (CP). | 26045748 |
| Primary malignant neoplasm, Benign prostatic hypertrophy, prostatitis | Altered Intercellular Communication | We investigated the expression of immune system-related biomarkers such as Interleukin (IL) -6 (humoral immunity), CD-3 (T-lymphocyte), and CD-163 (macrophage) in prostate biopsy (PBx) specimens from patients with prostatic inflammation (without cancer) which had been neither clinically diagnosed benign prostatic hyperplasia nor chronic prostatitis. | 26045748 |
| Pain Distress Question, prostatitis | Altered Intercellular Communication | Our results showed CD-163 (macrophage) reflected pain or discomfort on NIH-CPSI scores (P=0.0389 and r=0.3307) in the patients with prostatic inflammation; however, the control patients had no significant correlation between symptom scores and those immune-related markers' expression. | 26045748 |
| Pain Distress Question, prostatitis | Altered Intercellular Communication | These results suggest that pain or discomfort related to macrophages in the relationship between immune-system and the symptom of prostatic inflammation. | 26045748 |
| Pain Distress Question, Lower Urinary Tract Symptoms, prostatitis | Altered Intercellular Communication | In conclusion, CD-163, related to immune-system (macrophage), correlated with symptoms (pain or discomfort) of prostatic inflammation and might represent a significant immune-system related biomarker for pain or LUTS score in potentially CP. | 26045748 |
| Inflammation, Abscess, Fasciitis | Altered Intercellular Communication | This case represents an unusual complication of a common disease and we should bear in mind that retroperitoneal inflammation and/or abscesses may cause necrotizing fasciitis through lumbar triangles. | 26045863 |
| Inflammation, Infection | Altered Intercellular Communication | Infections and inflammation of the lower limb skin, soft tissues, and vessels are more common than in other body regions. | 26046245 |
| Inflammation, Dysautonomia, Familial | Altered Intercellular Communication | In addition to accumulation of a-galactosidase A substrates, other mechanisms may be involved in FD pathophysiology, such as inflammation and oxidative stress. | 26046974 |
| Inflammation, Bronchiectasis, Fibrosis Assessment, Repeat, Lung diseases | Altered Intercellular Communication | Lung disease in cystic fibrosis (CF) involves excessive inflammation, repetitive infections and development of bronchiectasis. | 26047144 |
| Inflammation, Prostate carcinoma | Altered Intercellular Communication | We previously found that inflammation in benign prostate tissue is associated with an increased odds of prostate cancer, especially higher-grade disease. | 26047319 |
| Inflammation, Prostate carcinoma | Altered Intercellular Communication | Our findings generally support the role of inflammation in the etiology of prostate cancer. | 26047319 |
| ACSM3 gene, Inflammation, Subarachnoid Hemorrhage, Aneurysm, Ruptured, Brain Injuries | Altered Intercellular Communication | Attempts to clarify mechanisms of early brain injury in subarachnoid hemorrhage (SAH) revealed a high-mobility group box 1 (HMGB1) protein involvement in sterile inflammation initiated by aneurysm rupture. | 26047599 |
| Inflammation | Altered Intercellular Communication | Low-tube-voltage 80 kVp neck CT provides increased enhancement of soft-tissue inflammation, CNR, raCNR, and improved abscess delineation in patients with PTA compared to standard 120 kVp acquisition while resulting in a significant reduction of radiation exposure. | 26050533 |
| Inflammation, Colorectal Carcinoma | Altered Intercellular Communication | Diet and inflammation have been suggested to be important risk factors for colorectal cancer (CRC). | 26050563 |
| Ulcerative Colitis | Altered Intercellular Communication | Level of Fecal Calprotectin Correlates With Endoscopic and Histologic Inflammation and Identifies Patients With Mucosal Healing in Ulcerative Colitis. | 26051392 |
| HD Term Type, Inflammation | Altered Intercellular Communication | Our study suggests that R-S-Y-R-T could decrease chronic inflammation and increase the life quality in HD patients. | 26051571 |
| Inflammation, Endothelial dysfunction, Ischemic stroke | Altered Intercellular Communication | Thromboinflammatory molecules connect the prothrombotic state, endothelial dysfunction, and systemic/local inflammation in the acute phase of ischemic stroke. | 26051664 |
| Inflammation, Psoriasis | Altered Intercellular Communication | Nonattenuation corrected FDG-PET images may be useful and preferable to AC images in assessing skin inflammation in psoriasis. | 26053710 |
| Inflammatory abnormality of the eye | Altered Intercellular Communication | Ocular Inflammation in the Setting of Concomitant Systemic Autoimmune Conditions in an Older Male Population. | 26053887 |
| Pain Distress Question, Irritation, Inflammation | Altered Intercellular Communication | PerioPatch(tm) is an approved device product that has been developed as an oral adhesive barrier for promoting healing in inflamed oral/gingival tissues and reducing pain, irritation, and the symptoms of inflammation. | 26053922 |
| Periodontitis, Periodontal Diseases | Altered Intercellular Communication | Periodontal disease (periodontitis) is a common inflammatory condition affecting the deep, supporting tissues around teeth. | 26053922 |
| Inflammation | Altered Intercellular Communication | MFAP5 is related to obesity-associated adipose tissue and extracellular matrix remodeling and inflammation. | 26054006 |
| Inflammation | Altered Intercellular Communication | Low-grade inflammation is involved in adipose tissue (AT) and extracellular matrix (ECM) remodeling and induces deposition of ECM proteins in AT. | 26054006 |
| Inflammation | Altered Intercellular Communication | Our results demonstrate that factors involving low-grade inflammation modulate MFAP5 expression and that the modified expression of MFAP5 may further regulate AT inflammation. | 26054006 |
| vascular inflammations, Cyclophosphamide/Vincristine/Dacarbazine Regimen, Cardiovascular Diseases | Altered Intercellular Communication | Increased oxidative stress and vascular inflammation are implicated in increased cardiovascular disease (CVD) incidence with age. | 26054376 |
| Inflammation | Altered Intercellular Communication | Systemic inflammation as a predictor of clinical outcomes after lower extremity angioplasty/stenting. | 26054584 |
| Inflammation, Failure (biologic function) | Altered Intercellular Communication | Although the global influence of angioplasty/stenting on systemic inflammation was modest, circulating cytokine and monocyte genome analyses support a pattern of early inflammation that is associated with ultimate intervention success vs failure. | 26054584 |
| Inflammation, Diabetes Mellitus, Non-Insulin-Dependent | Altered Intercellular Communication | Chronic stress and chronic low-grade inflammation are prominent risk factors for T2D development in pre-diabetic subjects. | 26055228 |
| Inflammation, Prediabetes syndrome, Diabetes Mellitus, Non-Insulin-Dependent | Altered Intercellular Communication | However, molecular mechanisms mediating effect of stress and inflammation on development of T2D from pre-diabetes remain unknown. | 26055228 |
| Inflammation, Prediabetes syndrome, Diabetes Mellitus, Non-Insulin-Dependent | Altered Intercellular Communication | Our results provide further support of "kynurenine hypothesis of insulin resistance and its progression to T2D" that suggested that overproduction of diabetogenic KP metabolites, induced by chronic stress or chronic low-grade inflammation, is one of the mechanisms promoting development of T2D from pre-diabetes. | 26055228 |
| Inflammation, Sleep Apnea, Obstructive | Altered Intercellular Communication | Vascular endothelial inflammation and enhanced oxidative stress are important factors in the pathogenesis of obstructive sleep apnea syndrome (OSAS). | 26055465 |
| Schizophrenia, Rhabdomyositis, Tropical pyomyositis, Necrosis | Altered Intercellular Communication | Owing to serial increases (up to 1310 U/L) in serum creatine kinase and a history of local intramuscular paliperidone injections for management of schizophrenia, surgical exploration was performed and identified necrotising skeletal muscle inflammation and extensive fat necrosis with an organising abscess, consistent with pyomyositis. | 26055607 |
| Inflammation, Psoriasis | Altered Intercellular Communication | Leukocyte-derived koebnerisin (S100A15) and psoriasin (S100A7) are systemic mediators of inflammation in psoriasis. | 26055798 |
| Inflammation | Altered Intercellular Communication | In the skin, the antimicrobial proteins koebnerisin (S100A15) and psoriasin (S100A7) are overexpressed in the epidermis of psoriatic lesions and mediate inflammation as chemoattractants for immune cells. | 26055798 |
| Ulceration, CTCAE, Gastrointestinal mucositis | Altered Intercellular Communication | Ten patients with plasma cell-rich chronic inflammatory conditions of the oral mucosa were identified (seven--plasma cell mucositis and three--non-specific diffuse oral mucosal inflammation with ulceration). | 26056156 |
| Ulceration, CTCAE, Gastrointestinal mucositis | Altered Intercellular Communication | Ten patients with plasma cell-rich chronic inflammatory conditions of the oral mucosa were identified (seven--plasma cell mucositis and three--non-specific diffuse oral mucosal inflammation with ulceration). | 26056156 |
| vascular inflammations, Hypertension, CTCAE, Endothelial dysfunction | Altered Intercellular Communication | Soluble vascular cell adhesion molecule-1 (sVCAM-1) is associated with hypertension, vascular inflammation, and systemic endothelial dysfunction. | 26056332 |
| Inflammation, Depression, CTCAE | Altered Intercellular Communication | Several studies have been performed to validate the association between depression and inflammation in haemodialysis patients. | 26057312 |
| HD Term Type, Inflammation, Depression, CTCAE | Altered Intercellular Communication | Although IL-6 level was higher in HD compared to CAPD patients, the relationship between depression and presence of inflammation parametars were observed in CAPD, but not in HD patients. | 26057312 |
| Inflammation, Microvascular Angina | Altered Intercellular Communication | Does Inflammation Have a Role in the Pathogenesis of Cardiac Syndrome X? | 26058672 |
| Inflammation, Liver carcinoma | Altered Intercellular Communication | Imbalance in systemic inflammation and immune response following transarterial chemoembolization potentially increases metastatic risk in huge hepatocellular carcinoma. | 26058874 |
| Inflammation, Neoplasm Metastasis | Altered Intercellular Communication | Inflammation plays a critical role in tumor metastasis. | 26058874 |
| Liver carcinoma, Neoplasm Metastasis, FAM126A gene | Altered Intercellular Communication | However, few inflammation-related biomarkers are currently available to predict the risk of metastasis for advanced hepatocellular carcinoma (HCC). | 26058874 |
| Inflammation, Neoplasm Metastasis, FAM126A gene | Altered Intercellular Communication | Our findings suggest the potential contribution of treatment-related inflammation to metastasis in advanced HCC. | 26058874 |
| Inflammation | Altered Intercellular Communication | Intracranial delivery of the IL13-zetakine(+) CTL clones into the resection cavity of 3 patients with recurrent disease was well-tolerated, with manageable temporary brain inflammation. | 26059190 |
| Cancer of Urinary Tract, Cerebrovascular accident | Altered Intercellular Communication | In contrast, DRGs 14 (stroke), 79 (respiratory infections/ inflammations), and 320 (kidney/urinary infections) had a smaller reduction in dementia-associated adjusted odds ratio (0.41-0.46) for home discharge. | 26059911 |
| Inflammation, Metabolic Syndrome X, Refractory anemias, ETV3 wt Allele, Degenerative polyarthritis, Rheumatoid Arthritis | Altered Intercellular Communication | The purpose of the study was to examine whether rheumatoid arthritis (RA) patients have higher prevalence of metabolic syndrome (MetS) than osteoarthritis (OA) patients in association with a higher level of chronic systemic inflammation in rheumatoid arthritis. | 26059944 |
| Inflammation | Altered Intercellular Communication | Rebamipide improves chronic inflammation in the lesser curvature of the corpus after Helicobacter pylori eradication: a multicenter study. | 26060821 |
| Inflammation | Altered Intercellular Communication | Chronic inflammation affecting the lesser curvature of the corpus was significantly improved in the rebamipide group compared to in the untreated group (1.12 +- 0.08 versus 1.35 +- 0.08; P = 0.043). | 26060821 |
| Inflammation | Altered Intercellular Communication | Rebamipide treatment after H. pylori eradication alleviated chronic inflammation in the lesser curvature of the corpus compared to that in the untreated group. | 26060821 |
| Abscess, Inflammation | Altered Intercellular Communication | The initial pathology report of the excised specimen confirmed the presence of nonspecific abscesses and inflammation. | 26061492 |
| Inflammation, Tissue injury | Altered Intercellular Communication | Positive end-expiratory pressure (PEEP) improves gas exchange and respiratory mechanics, and it may decrease tissue injury and inflammation. | 26061818 |
| Intraocular inflammation | Altered Intercellular Communication | [Incidence of endogenous intraocular inflammation patients who visited Nippon Medical School Hospital during the 8 years from 2004 to 2012]. | 26062391 |
| Intraocular inflammation | Altered Intercellular Communication | To report the clinical statistical analysis of patients with endogenous intraocular inflammation who visited Nippon Medical School Hospital during the 8 years from 2004 to 2012. | 26062391 |
| Intraocular inflammation | Altered Intercellular Communication | This retrospective study involved 759 new patients with endogenous intraocular inflammation who visited Nippon Medical School Hospital during the 8 years from April 2004 to April 2012. | 26062391 |
| Uveomeningoencephalitic Syndrome, Sarcoidosis, Scleritis, Intraocular inflammation | Altered Intercellular Communication | Sarcoidosis, scleritis and Vogt-Koyanagi-Harada disease were frequent intraocular inflammations in ophthalmologic patients at Nippon Medical School Hospital. | 26062391 |
| Granulomatous inflammation, GCA gene, Giant Cell Arteritis, Vasculitis, Takayasu Arteritis | Altered Intercellular Communication | Takayasu arteritis (TA) and giant cell arteritis (GCA) are large vessel vasculitides (LVV) that usually present as granulomatous inflammation in arterial walls. | 26062541 |
| Inflammation, Neoplasms | Altered Intercellular Communication | Time-Course Changes of Cardiac-Specific Inflammation in a Patient With Left Ventricular Calcified Amorphous Tumor. | 26062949 |
| Autoimmune Diseases, Rheumatoid Arthritis, Have Autoimmune or Inflammatory Condition, Refractory anemias | Altered Intercellular Communication | In autoimmune diseases such as rheumatoid arthritis (RA), regulatory T cells (Tregs) fail to constrain autoimmune inflammation; however, the reasons for this are unclear. | 26062995 |
| Hypertension, CTCAE, Hepatitis, Liver Cirrhosis | Altered Intercellular Communication | Abnormally high plasma levels of Nogo-B are associated with hepatic cirrhosis and Child-Pugh score, but not correlated with the grade of liver inflammation or portal hypertension. | 26063954 |
| Inflammation, Fibrosis Assessment | Altered Intercellular Communication | A skeletal muscle biopsy demonstrated vacuolar myopathic changes (acid phosphatase negative) accompanied by focal endomysial fibrosis and chronic inflammation. | 26067541 |
| Inflammation, Diabetes Mellitus | Altered Intercellular Communication | Diabetes mellitus type 2 (DMT2) is accompanied by systemic low-grade inflammation with elevated levels of interleukin-6 (IL-6), which is encoded by a gene (IL-6) previously shown to be regulated by DNA methylation. | 26067576 |
| Interstitial Fibrosis Assessment, Interstitial inflammation, Tubular atrophy | Altered Intercellular Communication | Those of interstitial fibrosis and tubular atrophy classes 0, 1, 2, and 3 were 0, 7, 9, and 11, and those of interstitial inflammation classes 0, 1, and 2 were 0, 3, and 4, respectively. | 26067713 |
| Inflammation | Altered Intercellular Communication | Nuclear factor kappa B (NF-kB) pathway proteins play an important role in modulating inflammation and other carcinogenic processes. | 26068031 |
| Colon Carcinoma, Inflammation, Neoplasms | Altered Intercellular Communication | Microsatellite instable vs stable colon carcinomas: analysis of tumour heterogeneity, inflammation and angiogenesis. | 26068398 |
| Orbital Pseudotumor | Altered Intercellular Communication | Slides were reviewed by a masked ocular pathologist who evaluated the level of orbital inflammation. | 26068557 |
| Granulomatous inflammation, Inflammation | Altered Intercellular Communication | Histopathology demonstrated foci of granulomatous inflammation in the orbit of the patient and similar inflammation in the rat orbits injected with retrobulbar alcohol. | 26068557 |
| Inflammation, Orbital Pseudotumor | Altered Intercellular Communication | Our findings in this preclinical pilot study suggest that retrobulbar alcohol injections incite significant orbital inflammation, whereas retrobulbar chlorpromazine induces little or no inflammation. | 26068557 |
| Inflammation, Diabetes Mellitus | Altered Intercellular Communication | Low-grade inflammation, as measured by hs-CRP level, may have an important role in the development of diabetes among African Americans with a lesser degree of insulin resistance. | 26068864 |
| Carpal Tunnel Syndrome, Inflammation | Altered Intercellular Communication | Carpal tunnel syndrome (CTS), can also occur in BD patients secondary to inflammation in the connective tissues, vessels, and tendons, as well as nerve involvement in BD itself. | 26069125 |
| Carpal Tunnel Syndrome, Inflammation | Altered Intercellular Communication | CTS can occur as a result of the inflammation associated with BD and can also be the presenting symptom of nerve involvement in BD. | 26069125 |
| Inflammation | Altered Intercellular Communication | Vascular access (VA) devices may contribute to chronic inflammation in hemodialysis (HD). | 26070095 |
| Urinary tract infection, prostatitis | Altered Intercellular Communication | In our study, suprapubic trocar placement (11/12), chronic prostatic inflammation (9/12), previous UTI (3/12) and extended resection (2/12) were overrepresented. | 26070659 |
| Inflammation, Restless Legs Syndrome | Altered Intercellular Communication | Association of restless legs syndrome with oxidative stress and inflammation in patients undergoing hemodialysis. | 26070856 |
| Inflammation, Dysplasia of anus | Altered Intercellular Communication | Morphologic evaluation of anal dysplasia remains problematic, especially in cases with limited biopsy samples or obscuring inflammation. | 26071469 |
| Prostate carcinoma, prostatitis | Altered Intercellular Communication | Is histological prostate inflammation in an initial prostate biopsy a predictor of prostate cancer on repeat biopsy? | 26071871 |
| Inflammation, Prostate carcinoma | Altered Intercellular Communication | To investigate whether histological inflammation detected in an initial prostate biopsy can predict the risk of prostate cancer on a repeat biopsy. | 26071871 |
| Aggressive behavior, prostatitis, Primary malignant neoplasm | Altered Intercellular Communication | Prostate inflammation grade (p = 0.005) and aggressiveness (p = 0.001) in the initial biopsy were significantly different between the cancer and noncancer groups. | 26071871 |
| Prostate carcinoma | Altered Intercellular Communication | Factors associated with the risk of prostate cancer at the repeat biopsy were age [odds ratio (OR) 1.08; 95 % confidence interval (CI) 1.03-1.14], prostate-specific antigen density (OR 24.30; 95 % CI 9.3-62.9), prostate-specific antigen velocity (OR 1.05; 95 % CI 1.01-1.09), and inflammation aggressiveness (OR 0.05; 95 % CI 0.01-0.27). | 26071871 |
| Inflammation, Biliary calculi, Fibrosis Assessment, Pancreas, Obstruction of biliary tree, Calcinosis, Phlebitis, Cortical irregularity | Altered Intercellular Communication | Pathologically, the average inflammatory mass diameter was 3.8 +- 3.3 cm, biliary obstruction occurred in 36 cases, gall stones in 70 cases, calcification in 88 cases, ductal dilatation in 61 cases, side branch dilatation in 32 cases, ductal irregularity in 10 cases, lymphocytic inflammation in 23 cases, obliterative phlebitis in 14 cases, extra pancreatic lesion in 19 cases and fibrosis in 142 cases. | 26072078 |
| Sepsis, Communicable Diseases | Altered Intercellular Communication | Sepsis is the syndrome of body-wide inflammation triggered by infection and is a major public health problem. | 26072206 |
| Communicable Diseases, Inflammation, Hypersensitivity | Altered Intercellular Communication | It may cause some adverse effects such as local inflammation, infection, and allergic reactions on the skin and even systemic adverse effects such as sarcoidal reactions. | 26073118 |
| Inflammation, Diabetes Mellitus, Non-Insulin-Dependent, Obesity | Altered Intercellular Communication | Chinese patients with obesity and type II diabetes have significantly lower plasma CTRP-3 concentrations than healthy subjects do, and plasma CTRP-3 is strongly associated with glucose and lipid metabolism, chronic inflammation, and insulin resistance. | 26073386 |
| Inflammation | Altered Intercellular Communication | Runners with exercise-induced high blood pressure have recently been reported to exhibit higher levels of cardiac markers, vasoconstrictors, and inflammation. | 26073606 |
| Inflammation, Rupture | Altered Intercellular Communication | Inflammation is a key factor in the development of plaque rupture and acute cardiovascular events. | 26074318 |
| Inflammation, Hypoxia, Colorectal Carcinoma, Neoplasms | Altered Intercellular Communication | Summarizing, our results link Nampt/PBEF/visfatin with tumor metastatic potential and point at inflammation and hypoxia as key inducers of its upregulation in CRC. | 26075243 |
| Conjunctivitis | Altered Intercellular Communication | A third patient presented with nodular conjunctival inflammation, which initially had been treated with topical ciprofloxacin and corticosteroids without improvement. | 26075451 |
| Inflammation, Inflammatory disorder | Altered Intercellular Communication | NF-kB, a central regulator of inflammation, is involved in various inflammatory diseases. | 26075620 |
| Inflammation | Altered Intercellular Communication | The interaction between fatness, fitness, and C-reactive protein (CRP) in adolescents is not well characterized but may be important to prevent low grade inflammation. | 26075745 |
| Inflammation, Primary malignant neoplasm, Metabolic Syndrome X, Cardiovascular Diseases, Diabetes Mellitus | Altered Intercellular Communication | The role of Clusterin in attenuation of inflammation and reverse cholesterol transfer makes this molecule a potential candidate as a marker for cancer, cardiovascular disease, diabetes mellitus, and metabolic syndrome. | 26076476 |
| Inflammatory Bowel Diseases, Inflammation | Altered Intercellular Communication | The Relationship Among Perceived Stress, Symptoms, and Inflammation in Persons With Inflammatory Bowel Disease. | 26077178 |
| Gastrointestinal inflammation | Altered Intercellular Communication | The association between perceived stress and gastrointestinal inflammation is not well described. | 26077178 |
| Inflammation, Gastrointestinal inflammation | Altered Intercellular Communication | Intestinal inflammation was determined through measurement of fecal calprotectin (FCAL), with a level exceeding 250 mg/g indicating significant inflammation. | 26077178 |
| Gastrointestinal inflammation, Ulcerative Colitis | Altered Intercellular Communication | There was no significant association between perceived stress and intestinal inflammation for either CD or UC. | 26077178 |
| Gastrointestinal inflammation, Ulcerative Colitis | Altered Intercellular Communication | Active symptoms (MIBDI <=3) were associated with intestinal inflammation in UC (odds ratio (OR) 3.94, 95% CI 1.65-9.43), but not in CD (OR 0.98, 95% CI 0.51-1.88). | 26077178 |
| Gastrointestinal inflammation, Ulcerative Colitis | Altered Intercellular Communication | Symptomatic disease activity was unrelated to intestinal inflammation in CD and only weakly associated in UC. | 26077178 |
| Gastrointestinal inflammation | Altered Intercellular Communication | Although there was a strong relationship between perceived stress and gastrointestinal symptoms, perceived stress was unrelated to concurrent intestinal inflammation. | 26077178 |
| Inflammatory Bowel Diseases, Inflammation | Altered Intercellular Communication | Longitudinal investigation is required to determine the directionality of the relationship between perceived stress, inflammation, and symptoms in IBD. | 26077178 |
| Inflammation, Non-alcoholic Fatty Liver Disease, Psoriasis | Altered Intercellular Communication | Nonalcoholic fatty liver disease, spleen and psoriasis: New aspects of low-grade chronic inflammation. | 26078565 |
| Inflammation, Atherosclerosis | Altered Intercellular Communication | Intercellular adhesion molecule-1 (ICAM-1) displays an important role in the development of the inflammation reaction and atherosclerosis. | 26078712 |
| Inflammation, Primary malignant neoplasm, Breast Carcinoma | Altered Intercellular Communication | Breast cancer is the most common cancer among women, and both low-grade inflammation and cathepsins might have important roles in breast cancer. | 26079659 |
| Inflammation, Data Type -Character | Altered Intercellular Communication | Clinical symptoms (Harvey-Bradshaw Index [HBI]), disease character, serological markers of inflammation [C-reactive protein], and endoscopic evaluation were collected and reviewed by two independent IBD-specialty physicians. | 26079723 |
| Inflammation, Ulcerative Colitis | Altered Intercellular Communication | The severity of inflammation at onset of ulcerative colitis is not associated with IBS-like symptoms during clinical remission. | 26079726 |
| Inflammation, Ulcerative Colitis | Altered Intercellular Communication | The severity and extent of inflammation at onset of UC do not seem to affect the development of IBS-like symptoms in UC patients during clinical remission. | 26079726 |
| Inflammation | Altered Intercellular Communication | This technique could avoid autogenous bone grafting or permanent alloplastic implantation, which may cause a foreign body reaction, chronic inflammation, and migration. | 26080197 |
| Communicable Diseases, Inflammation, Malignant Neoplasms | Altered Intercellular Communication | Diagnosis of Gorham-Stout can only be made after excluding other common causes of bony resorption such as those caused by infection, inflammation, malignancy, and endocrine. | 26080240 |
| Inflammatory Bowel Diseases, Inflammation, Ulcerative Colitis | Altered Intercellular Communication | Macrophage and dendritic cell subsets in IBD: ALDH+ cells are reduced in colon tissue of patients with ulcerative colitis regardless of inflammation. | 26080709 |
| Cardiovascular Diseases | Altered Intercellular Communication | Almonds reduce cardiovascular disease risk via cholesterol reduction, anti-inflammation, glucoregulation, and antioxidation. | 26080804 |
| Inflammation, Feeling calm | Altered Intercellular Communication | A randomized, controlled, crossover trial was conducted in Boston, MA to test whether as compared to a control NCEP Step 1 diet absent nuts (CON), incorporation of almonds (85 g/day) into the CON diet (ALM) would improve vascular function and inflammation. | 26080804 |
| Barrett Esophagus, Adenocarcinoma Of Esophagus | Altered Intercellular Communication | We also evaluated expression in the precursor lesion of esophageal adenocarcinoma, Barrett's esophagus, which emerges following gastric reflux-induced esophageal inflammation, and found PD-L2 expression in Barrett's esophagus but not in non-Barrett's esophagus esophagitis. | 26081225 |
| Human papilloma virus infection, Primary malignant neoplasm, Uterine Cervicitis, Cervical Intraepithelial Neoplasia | Altered Intercellular Communication | The HPV infection rates for the patients with cervical inflammation, CIN, and cancer were 18.18%, 64.71%, and 100%, respectively. | 26081269 |
| Inflammation, Atherosclerosis | Altered Intercellular Communication | Inflammation and atherosclerosis are associated with many age-related conditions and atherosclerosis has been associated with olfactory decline in middle-aged adults. | 26082178 |
| Inflammation, Diabetes Mellitus, Non-Insulin-Dependent | Altered Intercellular Communication | To study the expression pattern of microRNAs and mRNAs related to inflammation in T2D monocytes. | 26083362 |
| muscle mass, Myositis | Altered Intercellular Communication | In view of the lack of accretion of muscle mass in response to the alpine skiing intervention, we hypothesize that local muscle inflammation and oxidative stress may have blunted the anabolic response to training and promoted muscle breakdown in this elderly post-TKA population. | 26083700 |
| Arthritis | Altered Intercellular Communication | The up-regulated CD64(+) monocytes seem to be have an important role in psoriatic joint inflammation. | 26084203 |
| vascular inflammations, Vessel perforation | Altered Intercellular Communication | The e4 allele is considered to promote Ab deposition on the vessel wall, and e2 is speculated to trigger vessel ruptures or vascular inflammation. | 26084230 |
| vascular inflammations, Calcification of coronary artery | Altered Intercellular Communication | Elevated serum uric acid is associated with vascular inflammation but not coronary artery calcification in the healthy octogenarians: the Brazilian study on healthy aging. | 26084248 |
| Inflammation, Calcification of coronary artery, SLC25A20 gene | Altered Intercellular Communication | We evaluated the association of SUA, highly sensitive C-reactive protein (hs-CRP, a marker of vascular and systemic inflammation), and coronary artery calcification (CAC, a marker of subclinical CVD) in a cohort of Brazilian octogenarians (>=80 years) free from known clinical CVD. | 26084248 |
| vascular inflammations, Coronary Arteriosclerosis, SLC25A20 gene | Altered Intercellular Communication | In the healthy octogenarians, higher SUA levels are associated with vascular inflammation (hs-CRP) but not with coronary atherosclerosis (CAC); markers for the subclinical CVD. | 26084248 |
| Sepsis, vascular inflammations, Cardiovascular Diseases | Altered Intercellular Communication | Our results provide insight into the control of vascular inflammation by IL-35 and suggest that IL-35 is an attractive novel therapeutic reagent for sepsis and cardiovascular diseases. | 26085094 |
| Inflammation, Apoptosis, Impaired Circulation | Altered Intercellular Communication | The intrinsic risk factors of rotator cuff disease (RCD) include degeneration, inflammation, oxidative stress, and circulation impairment. | 26085191 |
| Inflammation | Altered Intercellular Communication | However, mini-implants may cause injury to adjacent teeth or anatomical structures and may lead to tissue inflammation. | 26085484 |
| Inflammation, Rheumatoid Arthritis | Altered Intercellular Communication | First step in the development of an ultrasound joint inflammation score for rheumatoid arthritis using a data-driven approach. | 26085490 |
| Refractory anemias, Inflammation, Rheumatoid Arthritis | Altered Intercellular Communication | To develop and validate candidate sets of joints and tendons for assessment of ultrasound (US) joint inflammation in rheumatoid arthritis (RA). | 26085490 |
| Inflammation | Altered Intercellular Communication | Neopterin has been considered as an important marker of cellular inflammation. | 26086324 |
| Communicable Diseases, Inflammation | Altered Intercellular Communication | Numerous studies have been suggested that even in the absence of acute infection ageing associated with chronic low-grade inflammation and the underlying cause of this process may be an immunosenescence as well as shifts production of cytokines levels. | 26087730 |
| Hyperlipidemia | Altered Intercellular Communication | It is well-known that permanent stimulation of immune responses may lead to hyperlipidemia that, in its turn, may evoke immune disturbances and affect the auto-inflammation processes. | 26087731 |
| Inflammatory Bowel Diseases, Inflammation | Altered Intercellular Communication | However, the initiation of inflammation and progression to IBD pathogenesis in a given individual is poorly understood. | 26088200 |
| Inflammatory Bowel Diseases, Inflammation, Ulcerative Colitis, Crohn Disease | Altered Intercellular Communication | The patient presented with a severe onset of disease, which was first suspected to be ulcerative colitis on outpatient examination and was later corrected to IBD with Crohn's-like features due to high systemic inflammation, mixed lymphocytic-granulocytic infiltrates in gastric biopsies, and further characteristics suggestive of Crohn's disease. | 26088200 |
| Inflammation, Fibrosis Assessment, Hepatitis | Altered Intercellular Communication | We investigated the correlation between the red cell distribution width (RDW) and RDW-to-platelet ratio (RPR) with the degree of inflammation and fibrosis in chronic hepatitis patients with different etiologies and in native and transplanted liver. | 26088296 |
| Fibrosis Assessment, Hepatitis, Liver Cirrhosis, End Stage Liver Disease | Altered Intercellular Communication | The correlation among the RDW, RPR, and model for end-stage liver disease (MELD) score with the degree of liver inflammation, fibrosis, and cirrhosis in separate groups of native and transplanted liver was calculated. | 26088296 |
| Symptoms, Inflammatory abnormality of the eye | Altered Intercellular Communication | In vivo detection of clinically non-apparent ocular surface inflammation in patients with meibomian gland dysfunction-associated refractory dry eye symptoms: a pilot study. | 26088680 |
| Symptoms, Keratitis, Meibomian gland dysfunction | Altered Intercellular Communication | The utility of in vivo confocal microscopy (IVCM) in the investigation of palpebral conjunctival and corneal inflammation in patients with meibomian gland dysfunction (MGD)-associated refractory dry eye symptoms following gland expression, despite objective clinical improvement. | 26088680 |
| Inflammation | Altered Intercellular Communication | MGD-associated refractory symptoms and the symptom-sign disparity may be explained by clinically non-apparent, active inflammation of the palpebral conjunctiva as detected by IVCM. | 26088680 |
| Airway structure | Altered Intercellular Communication | qPCR identifies a significant number of patients with potentially bacteria-associated neutrophilic airway inflammation and disease that are not identified by traditional culture-based methods. | 26089657 |
| Communicable Diseases, Inflammation, "Grisels syndrome", Subluxation of atlantoaxial joint | Altered Intercellular Communication | Grisel's syndrome is a nontraumatic atlantoaxial subluxation, usually secondary of an infection or an inflammation at the head and neck area, or after surgery in the same area. | 26090020 |
| Degenerative polyarthritis, Inflammation, Pain Distress Question | Altered Intercellular Communication | OA is closely associated with angiogenesis and the inhibition of angiogenesis presents a novel therapeutic approach to reduce inflammation and pain in OA. | 26090403 |
| Inflammation | Altered Intercellular Communication | Hr-anxA1 may offer pharmacological means to treat chronic atherogenesis by reducing FPR-2 dependent neutrophil rolling and adhesion to activated endothelial cells and by reducing total plaque inflammation. | 26090792 |
| Inflammation, Dental Plaque | Altered Intercellular Communication | Interestingly, inflammation was significantly correlated with neovessel formation (r=0.43, p=0.0008), hemosiderin spots (r=0.62, p<0.0001), and IPH (r=0.349, p=0.0097), suggesting that inflammation may be a key factor in plaque vulnerability. | 26090834 |
| Inflammation, Carotid Stenosis | Altered Intercellular Communication | Communication of inwardly projecting neovessels with the lumen and inflammation synergistically contribute to IPH and symptomatic presentations in patients with carotid stenosis and are more specific than the vasa vasorum. | 26090834 |
| Inflammation | Altered Intercellular Communication | This condition could be a new therapeutic target, and regression of luminal neovessel sprouting and inflammation may help to prevent IPH development and a symptomatic presentation. | 26090834 |
| Necrotizing granulomatous inflammation, Pseudolymphoma, Malignant Neoplasms | Altered Intercellular Communication | The most common lymph node pathologies in CHBAH are malignancies, nonspecific reactive lymphoid hyperplasia, necrotizing granulomatous inflammation and HIV reactive nodes. | 26091519 |
| Inflammation, Mucous Membrane | Altered Intercellular Communication | It is well established that secondary scar formation caused by inflammation and mucosal injury are the main mechanisms by which stenosis occurs. | 26091844 |
| Cessation of life, Hypertrophy | Altered Intercellular Communication | Progressive cardiac remodelling was stimulated through hypertrophy and death of individual cardiomyocytes, with infiltration, proliferation and activation of fibroblast and inflammatory cells, leading to increased angiogenic and inflammatory signalling. | 26092119 |
| selenium, Epilepsy, Status Epilepticus | Altered Intercellular Communication | Inflammation-related epilepsy is increasingly recognized; however, studies on status epilepticus (SE) are very infrequent. | 26092915 |
| Inflammatory abnormality of the eye | Altered Intercellular Communication | Outcome measures include ocular surface inflammation, fornix reformation, and restoration of ocular motility. | 26093286 |
| Periodontal Diseases | Altered Intercellular Communication | Evidence exists that periodontal disease treatment may reduce inflammatory mediators in gingival crevicular fluid (GCF) and the risk of inflammation-associated pregnancy complications. | 26093363 |
| Inflammation, Urethral Stenosis | Altered Intercellular Communication | Urethral strictures in transplant patients may arise due to many factors, such as repetitive urethral catheterization and inflammation. | 26093713 |
| Inflammation, Carotid artery calcification, Diabetes Mellitus | Altered Intercellular Communication | Diabetes modifies the relationships among carotid plaque calcification, composition and inflammation. | 26093886 |
| Inflammation, Calcinosis, Dental Plaque, Diabetes Mellitus | Altered Intercellular Communication | Though plaque composition and calcification were not quantitatively affected, diabetes modified the relationships between plaque calcium, composition and inflammation. | 26093886 |
| Inflammation, Lymphedema | Altered Intercellular Communication | The attack frequency of inflammation of lymphatic vessels, the stage of lymphedema disease, and leg circumference were observed before and after the care. | 26094422 |
| Inflammation, Chronic liver disease | Altered Intercellular Communication | In 3 patients, liver biopsy was performed and revealed signs of inflammation and chronic liver disease, as enlarged densely infiltrated portal tracts with mild-to-moderate interface hepatitis. | 26094550 |
| Paresis, Myositis, CTCAE 5.0, Myositis | Altered Intercellular Communication | Sporadic inclusion body myositis (sIBM) is a systemic disease that is characterized by substantial skeletal muscle weakness and muscle inflammation, leading to impaired physical function. | 26095885 |
| Brain Injuries, Ischemic stroke | Altered Intercellular Communication | Nine previously reported stroke-associated miRNAs (miR-21, miR-23a, miR-29b, miR-124, miR-145, miR-210, miR-221, miR-223 and miR-483-5p) were measured by quantitative real time-PCR, and plasma high-sensitivity C-reactive protein (hs-CRP) and serum interleukin 6 (IL-6), the pro-inflammation markers in brain injury, were examined by enzyme-linked immunosorbent assay in 146 acute ischemic stroke patients and 96 healthy blood donors. | 26096228 |
| ARCN1 gene, Inflammation, Chronic Obstructive Airway Disease | Altered Intercellular Communication | We aimed to investigate the importance of neutrophil-lymphocyte ratio (NLR) in patients with chronic obstructive pulmonary disease (COPD) for identifying the severity of inflammation and recognition of acute exacerbation. | 26096858 |
| ARCN1 gene, Inflammation | Altered Intercellular Communication | Elevated NLR can be used as a marker similar to CRP, WBC and ESR, in the determination of increased inflammation in acutely exacerbated COPD. | 26096858 |
| Inflammation, bone destruction, Arthritis, Collagen-Induced | Altered Intercellular Communication | In vivo effects of aGalCer-stimulated NKT cells on inflammation and bone destruction were determined in mice with collagen-induced arthritis. | 26097058 |
| Inflammation, Endothelial dysfunction | Altered Intercellular Communication | This study suggests that TV viewing was unfavourably associated with several markers of inflammation and endothelial dysfunction. | 26097139 |
| Inflammation, Kit Ligand, human, atherosclerotic, Atherosclerosis | Altered Intercellular Communication | An accumulating body of evidence suggests that slow coronary flow (SCF) phenomenon seems to be an early-form of atherosclerosis and low-grade inflammation plays a major role in the atherosclerotic vascular processes. | 26097597 |
| Inflammation, Coronary heart disease, Choline Dehydrogenase, Mitochondrial | Altered Intercellular Communication | Inflammation is now believed to be responsible for coronary heart disease (CHD). | 26098632 |
| Ear discharge | Altered Intercellular Communication | In the article we described a case of 22 year old, mentally impairment women with bilateral otorrhea, in the past treated for external ear canal inflammation. | 26098654 |
| Pneumonitis | Altered Intercellular Communication | The microbiomes of humans are associated with liver and lung inflammation. | 26099252 |
| Inflammation, Primary malignant neoplasm, Carcinogenesis | Altered Intercellular Communication | Chronic inflammation, due to the disease itself, generates a microenvironment able to promote cancer development, but it is still controversial whether immunosuppressive therapy may contribute to carcinogenesis. | 26099279 |
| Pain Distress Question, Inflammation | Altered Intercellular Communication | Metallosis as a cause of pain and inflammation in a patient with a knee replacement: A case description. | 26099454 |
| Communicable Diseases, Inflammation | Altered Intercellular Communication | As well as standard diagnostic procedures, patients will undergo whole body PET CT scan to localise infection or inflammation. | 26101020 |
| Inflammation, Sleep Apnea, Obstructive | Altered Intercellular Communication | T, B, and NKT Cells in Systemic Inflammation in Obstructive Sleep Apnoea. | 26101459 |
| Inflammation, Osage language | Altered Intercellular Communication | The grade of OSA complication score correlated with systemic inflammation markers and the proportion of B cells. | 26101459 |
| Iron-Refractory Iron Deficiency Anemia, Inflammation, Leukocytosis | Altered Intercellular Communication | Laboratory findings revealed inflammation with an increased C-reactive protein level (127 mg/L [1209 nmol/L]), leukocytosis (13 800/mm(3)), and microcytic anemia (hemoglobin level, 7.2 g/dL). | 26101924 |
| Prostatic Intraepithelial Neoplasias, Interstitial inflammation, Benign prostatic hypertrophy | Altered Intercellular Communication | Of the remaining 13 patients, 6 were found to be histologically positive for Benign Prostatic Hypertrophy and 7 Chronic Interstitial Inflammation or High Grade Prostatic Intraepithelial Neoplasia. | 26102053 |
| Inflammation, Peripheral vascular alteration | Altered Intercellular Communication | 12 (12/34) patients found to have no peripheral alterations in their prostate on 3T MRSI, none were positive for ADK or inflammation on histology. | 26102053 |
| Inflammation, Bone necrosis | Altered Intercellular Communication | Focal bone necrosis and inflammation were infrequent MRI findings. | 26102409 |
| Inflammation, Data types - Address | Altered Intercellular Communication | There is relatively little information about inflammation in the DS brain and how the genetics of DS may alter inflammatory responses and modify the course of AD pathogenesis in this disorder. | 26103884 |
| Inflammation, Intestinal Diseases | Altered Intercellular Communication | Environmental enteropathy is subclinical inflammation of the upper gastrointestinal tract associated with reduced linear growth in developing countries. | 26103960 |
| Gastrointestinal inflammation, Intestinal Diseases | Altered Intercellular Communication | Serum endotoxin core antibody (EndoCab) concentration is a potential indicator of intestinal inflammation and integrity, and thus may be useful to predict environmental enteropathy. | 26103960 |
| Inflammation, Diabetes Mellitus | Altered Intercellular Communication | The reported results support the role of Mediterranean diet as a promising dietary tool for the primary prevention of diabetes, by attenuating inflammation and fostering total antioxidant capacity. | 26104243 |
| Inflammation, Metabolic Diseases | Altered Intercellular Communication | This dietary pattern may have therapeutic potential for many cardiometabolic disorders associated with inflammation and/or oxidative stress. | 26104243 |
| Erythema Multiforme, Hyperglycemia, Edema, Hyponatremia, DLST wt Allele, Inflammatory disease of mucous membrane | Altered Intercellular Communication | The DLTs included mucosal inflammation, hyponatremia, face edema, erythema multiforme, and hyperglycemia. | 26104654 |
| Inflammation, Endothelial dysfunction, Diabetes Mellitus, Non-Insulin-Dependent | Altered Intercellular Communication | Non-transferrin-bound iron is associated with biomarkers of oxidative stress, inflammation and endothelial dysfunction in type 2 diabetes. | 26104728 |
| Inflammation, Diabetes Mellitus, Non-Insulin-Dependent | Altered Intercellular Communication | Fenofibrate reduces inflammation in obese patients with or without type 2 diabetes mellitus via sirtuin 1/fetuin A axis. | 26105582 |
| Inflammation, Granuloma | Altered Intercellular Communication | Histopathology of the biopsy collected from the left thigh upper ulcer and occipital nodule both demonstrated chronic inflammation with granuloma formation and yeast-like elements. | 26105618 |
| Hair follicle structure, Perifolliculitis, Keratinization, function | Altered Intercellular Communication | The presence of D. folliculorum was strongly associated with hair follicle duct dilatation and hyperkeratinization and with perifollicular nongranulomatous inflammation (p = 0.00). | 26108058 |
| Inflammation, Keratinization, function | Altered Intercellular Communication | Hair follicle duct dilatation, hyperkeratinization, and perifollicular inflammation were also independently associated with chalazia (p = 0.040 and 0.031, respectively). | 26108058 |
| Inflammation, Diabetes Mellitus, Non-Insulin-Dependent, Cardiovascular Diseases | Altered Intercellular Communication | Levels of high-sensitivity C-reactive protein (hs-CRP) and adiponectin, reflecting chronic inflammation, are associated with cardiovascular disease in type 2 diabetes. | 26109470 |
| Inflammatory abnormality of the eye, Dry Eye Syndromes | Altered Intercellular Communication | Subconjunctival injection of 100 mL 25 mg/mL bevacizumab is a safe and efficient treatment for ocular surface inflammation of dry eye disease. | 26109847 |
| Inflammation | Altered Intercellular Communication | Ecor-LDC inhibitors other than lysine analogs may maintain sufficient lysine levels and attachment integrity to prevent periodontal inflammation. | 26110450 |
| Vasculitis, Takayasu Arteritis | Altered Intercellular Communication | Takayasu arteritis is a rare disease that expresses chronic, large vessel inflammation. | 26110486 |
| Inflammation, Synovial Hypertrophy, Hydrarthrosis, Refractory anemias, Erosion of bone, Enthesitis, Tenosynovitis | Altered Intercellular Communication | Among RA patients, 82 (67.21%) were diagnosed with joint effusion, 78 (63.93%) were synovial thickening and 59 (48.36%) were bone erosion, while no tenosynovitis, soft tissue inflammation or enthesitis was found. | 26110744 |
| PROS1 gene, Inflammation, Synovial Hypertrophy, Hydrarthrosis, Erosion of bone, Enthesitis, Tenosynovitis | Altered Intercellular Communication | However, among the patients with PsA, 75 (60.97%) were diagnosed with joint effusion, 68 (55.28%) were synovial thickening, 71 (57.72%) were bone erosion, 71 (57.72%) were tenosynovitis, 44 (35.77%) were soft tissue inflammation and 39 (31.70%) were enthesitis. | 26110744 |
| PROS1 gene, Inflammation, Enthesitis | Altered Intercellular Communication | HFU proved valuable in detecting soft tissue inflammation and enthesitis in the fingers of PsA patients. | 26110744 |
| Inflammation, moisture | Altered Intercellular Communication | To resolve these clinical challenges, it is essential clinicians implement the TIME framework (tissue, inflammation/infection, moisture, edge of wound) as a model of effective wound bed preparation. | 26110987 |
| Inflammation, Cerebrovascular accident | Altered Intercellular Communication | Immunomodulation by interleukin-33 is protective in stroke through modulation of inflammation. | 26111431 |
| Inflammation, Cerebrovascular accident | Altered Intercellular Communication | Cerebral stroke induces massive Th1-shifted inflammation both in the brain and the periphery, contributing to the outcome of stroke. | 26111431 |
| Multiple Organ Failure, Inflammation | Altered Intercellular Communication | OPN concentrations were related to disease severity and significantly correlated with established prognosis scores and classical as well as experimental markers of inflammation and multi-organ failure. | 26111529 |
| Inflammation, Postoperative Period | Altered Intercellular Communication | The rim sign was thought to be the result of reactive inflammation in the hepatic tissue adjacent to a postoperative abscess within the gallbladder fossa. | 26111711 |
| Myocarditis, Complete atrioventricular block, Cardiac sarcoidosis, Heart Block | Altered Intercellular Communication | Complete heart block (CHB) caused by myocardial inflammation is a serious consequence of cardiac sarcoidosis (CS) that requires early diagnosis for effective anti-inflammatory treatment. | 26111805 |
| Myocardial fibrosis, Myocarditis | Altered Intercellular Communication | We defined abnormal (18)F-FDG uptake on (18)F-FDG PET and increased T2-weighted signal on cardiac MRI as signs of myocardial inflammation and delayed enhancement (DE) on cardiac MRI as a sign of myocardial fibrosis. | 26111805 |
| Inflammation, Complete atrioventricular block | Altered Intercellular Communication | Focal inflammation in the interventricular septum was associated with CHB and might predict recovery from CHB after corticosteroids if it coexists with preserved wall thickness. | 26111805 |
| Inflammation, Ductal Carcinoma | Altered Intercellular Communication | Dense chronic inflammation surrounding ductal carcinoma in situ was associated with a high score (P = 0.034).All 13 cases with PR >= 90%, <= 1 mitotic figure and absence of dense chronic inflammation around ductal carcinoma in situ had a low score (100% specificity). | 26111975 |
| Inflammation, Ductal Carcinoma | Altered Intercellular Communication | A low score was not observed in any case with at least two of the following--negative PR, >1 mitotic figure, and/or presence of dense chronic inflammation around ductal carcinoma in situ (100% specificity). | 26111975 |
| Arterial calcification, Cerebrovascular accident, Chronic Kidney Diseases, Atherosclerosis | Altered Intercellular Communication | Elevated fibroblast growth factor 23 (FGF23), a hormone that regulates phosphate homeostasis, has been associated with mortality, cardiovascular events, and stroke, and to arterial calcification in chronic kidney disease, but its role in atherosclerosis is unclear and population-based studies are lacking. | 26112008 |
| Communicable Diseases, Inflammation, Skin irritation | Altered Intercellular Communication | There were no complications such as skin irritation and wound infection, except for 1 case of chronic inflammation. | 26112405 |
| Asthma, Bronchitis | Altered Intercellular Communication | Exhaled breath temperature (EBT) has recently been proposed as a noninvasive marker of bronchial inflammation in patients with asthma. | 26113222 |
| Asthma, Bronchial Obstruction, Bronchitis | Altered Intercellular Communication | We performed a comprehensive study to determine whether EBT is related to asthma control, disease severity, bronchial obstruction, or bronchial inflammation. | 26113222 |
| Inflammation, Non-Small Cell Lung Carcinoma | Altered Intercellular Communication | Inflammation triggered by alarmins plays a role in NSCLC pathogenesis. | 26113410 |
| Inflammation | Altered Intercellular Communication | Inflammation plays an important role in the pathophysiological process after carotid artery stenting (CAS). | 26113783 |
| Cessation of life, Inflammation | Altered Intercellular Communication | Thus, the lysosomal galectin puncta assay opens up new possibilities to study LMP in cell death and its role in other cellular processes such as autophagy, senescence, aging, and inflammation. | 26114578 |
| Inflammation, Postoperative infection | Altered Intercellular Communication | Dynamics of inflammation biomarkers C-reactive protein, leukocytes, neutrophils, and CD64 on neutrophils before and after major surgical procedures to recognize potential postoperative infection. | 26114621 |
| Inflammation | Altered Intercellular Communication | Operation time was significantly shorter (P = .0007), while immediate postoperative inflammation was significantly more severe (P = .001), in the iris fixation than in the scleral fixation group. | 26116261 |
| Astigmatism, Acute inflammation | Altered Intercellular Communication | Although operation time was shorter for iris fixation, it had several disadvantages, including induced astigmatism, immediate postoperative inflammation, earlier recurrence, and less stable refraction. | 26116261 |
| Fish-Eye Disease, Inflammation, Cytokeratin | Altered Intercellular Communication | Inflammation (ie, conjunctival injection, presence of keratic precipitates and intraocular signs) at the time of surgery for patients with FED was significant for developing rejection: 3.5 times greater compared with those with no inflammation (P = .02). | 26116262 |
| Inflammation, Chronic Obstructive Airway Disease | Altered Intercellular Communication | Acute exacerbations of chronic obstructive pulmonary disease (AECOPD) are associated with increased airway and systemic inflammation. | 26116425 |
| Airway structure | Altered Intercellular Communication | There is evidence that erdosteine accelerates recovery from AECOPD by reducing airway inflammation. | 26116425 |
| Renal Insufficiency | Altered Intercellular Communication | Corrected Neutrophil Gelatinase-Associated Lipocalin (NGAL) Level Adjusted by the Scoring System of an Inflammation Index for Screening Renal Dysfunction in Patients with Systemic Inflammation. | 26116587 |
| Renal Insufficiency, Inflammation | Altered Intercellular Communication | This study investigated the use of corrected neutrophil gelatinase-associated lipocalin (cNGAL) values to screen renal dysfunction in patients with systemic inflammation. | 26116587 |
| Renal Insufficiency, Inflammation | Altered Intercellular Communication | A measurement of cNGAL may provide helpful information for assessing patients with renal impairment, particularly in association with systemic inflammation. | 26116587 |
| Inflammation, Endothelial dysfunction, Intermittent Claudication | Altered Intercellular Communication | Increased oxidative stress and inflammation contribute to impaired walking capacity and endothelial dysfunction in patients with intermittent claudication (IC). | 26116711 |
| Unknown (origin) (qualifier value), Inflammation | Altered Intercellular Communication | Expression of IL-18 was statistically higher in the aqueous of patients with HLA-B27 associated AAU in comparison to either idiopathic AAU or controls, but this may reflect greater inflammation in this patient group. | 26116905 |
| Inflammation | Altered Intercellular Communication | The specific signature of inflammation may potentially be useful in developing new future therapies for AAU. | 26116905 |
| Minimal Disseminated Disease, Depressive disorder, Inflammation, Depression, CTCAE | Altered Intercellular Communication | Major depressive disorder (MDD) is a common consequence of interferon alpha (IFNa) treatment and important supporting evidence of a role of inflammation in the aetiology of depression. | 26117091 |
| palladium, Inflammation | Altered Intercellular Communication | Increased FA in the SN in PD indicates gliosis and inflammation in the nuclei, but possibly also intrusion of surrounding fibres into the shrinking structure. | 26118635 |
| Inflammation, Fibrosis Assessment | Altered Intercellular Communication | Pentraxin-2 (PTX-2), a serum protein, inhibits inflammation and fibrosis, and recombinant PTX-2 is being tested as an anti-fibrotic agent. | 26119353 |
| Inflammation, Primary angiitis of the central nervous system | Altered Intercellular Communication | PACNS is an uncommon condition causing inflammation and destruction of the blood vessels of the central nervous system. | 26119979 |
| Inflammation, Helicobacter pylori | Altered Intercellular Communication | Furthermore, the sensitivity, specificity, and positive and negative predictive values of type 3, 4, or 5 morphologies for predicting Helicobacter pylori positive were 94.28%, 96.66%, 98.50%, and 87.87%, respectively, correlated well with inflammation grading according to the Sydney classification (P < 0.01). | 26120585 |
| Inflammation, Infection caused by Helicobacter pylori | Altered Intercellular Communication | Our study suggests that gastric mucosal morphologic patterns in the Helicobacter pylori infected gastric mucosa can be reliably identified using C-NBI gastroscopy with good correlation with inflammation grading. | 26120585 |
| Inflammation, Choroiditis | Altered Intercellular Communication | Macular serpiginouschoroiditis is a rare variant of serpiginous choroiditis characterized by a severe recurrent inflammation of both central choroid and retinal pigment epithelium. | 26120655 |
| Parkinson Disease, Inflammation, Chronic Fatigue Syndrome, palladium | Altered Intercellular Communication | To study clinical characteristics of fatigue syndrome in patients with Parkinson's disease (PD) and a role of inflammation in its development. | 26120984 |
| Inflammation, Pregnancy Complications, Infectious, Liver Cirrhosis | Altered Intercellular Communication | We here investigated if low vitamin D levels might be associated with prognosis, inflammation and infectious complications in patients with cirrhosis. | 26121590 |
| Airway structure, Inflammation, Bronchial Obstruction, Bronchiectasis | Altered Intercellular Communication | The triplet of airway infection, inflammation and bronchial wall destruction associated with excessive matrix metalloproteinases (MMP) release and imbalance of tissue inhibitor metalloproteinase-1 (TIMP-1) is implicated in bronchiectasis. | 26122009 |
| Inflammation, Bronchiectasis | Altered Intercellular Communication | For bronchiectasis patients, baseline measurements consisted of sputum inflammation and MMP measurements, bacterial culture, spirometry and chest high-resolution computed tomography (HRCT). | 26122009 |
| Carcinoma, Ovarian Epithelial, Ascites | Altered Intercellular Communication | Inflammation-regulating factors in ascites as predictive biomarkers of drug resistance and progression-free survival in serous epithelial ovarian cancers. | 26122176 |
| Inflammation, Chronic Obstructive Airway Disease, Carcinoma of lung, Primary malignant neoplasm | Altered Intercellular Communication | Expansion of myeloid-derived suppressor cells in chronic obstructive pulmonary disease and lung cancer: potential link between inflammation and cancer. | 26122358 |
| Alzheimers Disease", Data types - Address | Altered Intercellular Communication | Alzheimer's disease (AD) is characterised by deficits in cholinergic neurotransmission and subsequent receptor changes. | 26122542 |
| Inflammation | Altered Intercellular Communication | Moderate correlation was found between MRI activity index and eAIS, mural enhancement degree and eAIS; and poor correlation was found between mesenteric inflammation score and eAIS, MRI activity index and AIS, however they were not statistically significant. | 26123842 |
| Inflammation, Non-alcoholic Fatty Liver Disease | Altered Intercellular Communication | Portal inflammation during NAFLD is frequent and associated with the early phases of putative hepatic progenitor cell activation. | 26124313 |
| Inflammation, Non-alcoholic Fatty Liver Disease | Altered Intercellular Communication | We investigated whether portal tract inflammation observed in non-alcoholic fatty liver disease (NAFLD) is associated with hepatic progenitor cell compartment activation, as thoroughly evaluated with different markers of the staminal lineage. | 26124313 |
| Inflammation, Fibrosis Assessment, Non-alcoholic Fatty Liver Disease | Altered Intercellular Communication | NAFLD activity score, fibrosis and portal inflammation were histologically evaluated. | 26124313 |
| Inflammation, Fibrosis Assessment | Altered Intercellular Communication | Portal inflammation was absent in a minority of patients, mild in 40% of cases and more than mild in about half of patients, showing a strong correlation with fibrosis (r=0.76, p<0.001). | 26124313 |
| Inflammation, Portal inflammation | Altered Intercellular Communication | Lobular inflammation, ballooning, myofibroblast activity and hepatic progenitor cell compartment activation were associated with portal inflammation by univariate analysis. | 26124313 |
| Portal inflammation | Altered Intercellular Communication | In the multivariate model, the only variable independently associated with portal inflammation was hepatic progenitor cell compartment activation (OR 3.7, 95% CI 1.1 to 12.6). | 26124313 |
| Inflammation, Fibrosis Assessment, Non-alcoholic Fatty Liver Disease | Altered Intercellular Communication | Portal inflammation is frequent during NAFLD and strongly associated with activation of putative hepatic progenitor cells since the first steps of their differentiation, portal myofibroblast activity and fibrosis. | 26124313 |
| Airway structure, Chronic Obstructive Airway Disease, Bronchial Hyperreactivity | Altered Intercellular Communication | Bronchial hyperresponsiveness, airway inflammation, and reversibility in patients with chronic obstructive pulmonary disease. | 26124655 |
| Airway structure, ARCN1 gene | Altered Intercellular Communication | To evaluate the relationship between BHR, lung function, and airway inflammation in COPD patients. | 26124655 |
| chronic inflammatory response | Altered Intercellular Communication | Consequently, the current diagnostic utility of plasma cfDNA quantification has not been thoroughly validated in subjects with chronic respiratory inflammation. | 26125447 |
| chronic inflammatory response, Sarcoidosis, Chronic Obstructive Airway Disease, Non-Small Cell Lung Carcinoma, Asthma | Altered Intercellular Communication | We measured plasma cfDNA concentrations in 50 resectable NSCLC patients, 101 patients with chronic respiratory inflammation (chronic obstructive pulmonary disease, sarcoidosis, or asthma) and 40 healthy volunteers using real-time PCR. | 26125447 |
| Non-Small Cell Lung Carcinoma | Altered Intercellular Communication | We found significantly higher plasma cfDNA levels in NSCLC patients than in subjects with chronic respiratory inflammation and healthy individuals (P<0.0001). | 26125447 |
| chronic inflammatory response | Altered Intercellular Communication | There were no significant differences in plasma cfDNA levels between patients with chronic respiratory inflammation and healthy volunteers. | 26125447 |
| Non-Small Cell Lung Carcinoma, Upper Respiratory Infections | Altered Intercellular Communication | The receiver-operating characteristics curve distinguishing NSCLC patients from subjects with chronic respiratory inflammation indicated 56% sensitivity and 91% specificity at the >5.25-ng ml(-1) cutoff (AUC=0.76). | 26125447 |
| IGA Glomerulonephritis, Glomerulonephritis, immunoglobulin A, Kidney Diseases | Altered Intercellular Communication | Immunoglobulin A (IgA) nephropathy (IgAN) is a common form of primary glomerulonephritis characterized by diffuse glomerular mesangial IgA1 deposition leading to mesangial proliferation and chronic glomerular inflammation. | 26125729 |
| Inflammation, Malignant Neoplasms | Altered Intercellular Communication | Knowledge of xanthogranulomatous inflammation is essential to avoid misdiagnosis of malignancy and excessive surgical intervention. | 26126317 |
| Gastric Ulcer, CTCAE 5, Carcinoma, Acute and chronic inflammation | Altered Intercellular Communication | H. pylori iceA type 2 was dominant and associated with cagA, chronic active inflammation, gastric ulcer and carcinoma. | 26126322 |
| Interstitial inflammation | Altered Intercellular Communication | We selected 480 interstitial inflammation samples for light and electron microscopy and immunohistochemistry of CD138, IgG and IgG4 test. | 26126500 |
| Inflammation, Chronic sinusitis, Craniosynostosis | Altered Intercellular Communication | To describe potential mechanisms by which pepsin induces inflammation in refractive chronic rhinosinusitis (CRS). | 26127000 |
| Inflammation, Acute HIV infection | Altered Intercellular Communication | However, in patients who initiated cART during acute HIV infection, mucosal CD4(+) T-cell numbers were fully preserved and markers of microbial translocation and inflammation reversed to normal. | 26129649 |
| Inflammation | Altered Intercellular Communication | The aorta in MFS was similar to the aorta in dilated TAV with regard to the presence of medial degeneration and apoptosis, while other markers for degeneration and aging like inflammation and progerin expression were low in MFS, comparable to BAV. | 26129868 |
| Colorectal Carcinoma, Gastrointestinal inflammation | Altered Intercellular Communication | The mucosal immune response in the setting of intestinal inflammation contributes to colorectal cancer. | 26130064 |
| Inflammation, COL4A2 wt Allele | Altered Intercellular Communication | Inquiry into monocyte-mediated pathways of inflammation and apoptosis may elucidate the basis for the observed association and may be targets for ICH neuroprotection. | 26130090 |
| Inflammation, Chronic disease | Altered Intercellular Communication | Dietary components that are known to affect chronic inflammation have been implicated in the etiology and prognosis of these chronic diseases. | 26130324 |
| Inflammation, Primary malignant neoplasm, Breast Carcinoma | Altered Intercellular Communication | Inflammation has been linked to cancer but its role in breast cancer is unclear. | 26130675 |
| Inflammatory Bowel Diseases, Inflammation | Altered Intercellular Communication | Iron deficiency is common in patients with inflammatory bowel disease (IBD), but can be difficult to diagnose in the presence of inflammation because ferritin is an acute phase reactant. | 26131803 |
| Inflammatory Bowel Diseases, Inflammation | Altered Intercellular Communication | IBD activity was assessed on markers of inflammation (C-reactive protein, endoscopy, fecal calprotectin). | 26131803 |
| Inflammation, Phlegmon, Fever, CTCAE, Lymphadenitis | Altered Intercellular Communication | Moreover, the finding of fever and lymphadenitis with intense local signs of inflammation and phlegmon is rarely seen as the initial manifestation of Kawasaki disease. | 26132362 |
| Inflammation, Chronic Kidney Diseases | Altered Intercellular Communication | A major component of increased mortality risk in people with chronic kidney disease (CKD) is associated with non-traditional cardiovascular risk factors including markers of inflammation. | 26132658 |
| Inflammation, Chronic Kidney Diseases | Altered Intercellular Communication | We studied whether a novel marker of systemic inflammation, elevated serum combined polyclonal immunoglobulin free light chains (cFLC), was an independent risk factor for increased all-cause mortality in people with CKD stage 3. | 26132658 |
| Inflammation, Chronic Kidney Diseases | Altered Intercellular Communication | To conclude, high cFLC levels predict increased mortality in people with stage 3 CKD, independent of established risk factors and other markers of inflammation. | 26132658 |
| Airway structure, Nasal Polyps, Chronic sinusitis | Altered Intercellular Communication | Airway Inflammation in Chronic Rhinosinusitis with Nasal Polyps and Asthma: The United Airways Concept Further Supported. | 26132710 |
| Airway structure, Asthma, Bronchitis | Altered Intercellular Communication | We aimed to test two hypotheses: (i) upper and lower airway inflammation in CRSwNP is uniform in agreement with the united airways concept; and (ii) bronchial inflammation exists in all CRSwNP patients irrespective of clinical asthma status. | 26132710 |
| Asthma, Bronchitis | Altered Intercellular Communication | Our findings support the united airways concept; however, we did not find evidence for subclinical bronchial inflammation in CRSwNP patients without asthma. | 26132710 |
| Airway structure, Nasal Polyps | Altered Intercellular Communication | Finally, this study indicates for the first time that nasal polyps potentially play an important role in the airway inflammation rather than being a secondary phenomenon. | 26132710 |
| Inflammation, Fibrosis Assessment, Injury of liver | Altered Intercellular Communication | Histological alterations were shown in 60% of patients, without serious liver injuries (no case of inflammation or significant fibrosis). | 26133749 |
| Inflammation, Neoplasms | Altered Intercellular Communication | Chronic inflammation as an important epigenetic and environmental factor for putative tumorigenesis and tumor progression may be associated with specific activation of Toll-like receptors (TLR). | 26134824 |
| Pancreatic carcinoma, Neoplasms | Altered Intercellular Communication | Functional analysis in human pancreatic cancer cells point to a significant role of both TLRs in chronic inflammation-mediated TLR7/TLR8 signaling leading to tumor cell proliferation and chemoresistance. | 26134824 |
| Inflammation | Altered Intercellular Communication | The ALHE was defined as an EH with a vascular "blow-out" pattern associated with a variable degree of inflammation. | 26135557 |
| Inflammation | Altered Intercellular Communication | Studies suggest that inflammation is associated with unfavorable outcome. | 26135695 |
| Calcinosis, Atherosclerosis | Altered Intercellular Communication | This signaling cascade is tightly involved in bone formation and mineralization, but may also propagate pathological extraosseous calcification conditions such as calcifying inflammation and atherosclerosis. | 26135899 |
| Infectious agent, prostatitis | Altered Intercellular Communication | Exposure to infectious agents has been considered to induce prostatic inflammation and cancerous transformation. | 26136219 |
| Brain Abscess, Meningitis | Altered Intercellular Communication | The brain abscess was accompanied by mild meningeal inflammation with negative blood and cerebrospinal fluid cultures. | 26137921 |
| Inflammation | Altered Intercellular Communication | In CD, E. coli-laden macrophages expressed high IL-10 & CD163 and lower TNFa, IL-23 & iNOS irrespective of macroscopic inflammation. | 26137941 |
| Inflammation | Altered Intercellular Communication | Persistence of E. coli within LP macrophages may provide a stimulus for chronic inflammation. | 26137941 |
| Inflammation | Altered Intercellular Communication | Interestingly, SFs from grade 1 and non-OA patient could reduce released NO to 27.10 +- 2.2 mM/ml showing potency to alleviate inflammation. | 26138240 |
| Inflammation, Squamous cell carcinoma, Dysplasia, Hyperplasia | Altered Intercellular Communication | The physiologic and pathologic mucosa was described in five obvious vascular patterns observed at Enhanced Contact Endoscopy ranging from normal to squamous cell carcinoma, passing through inflammation, hyperplasia, and dysplasia. | 26138390 |
| Inflammation, Dysplasia, Carcinoma, Hyperplasia | Altered Intercellular Communication | Sensitivity, specificity, positive predictive value, and negative predictive value in the differentiation between healthy mucosa and inflammation versus pathologic hyperplasia, dysplasia, and carcinoma were, respectively, 96.6, 93.3, 98.2, 87.5, and 95.9 %. | 26138390 |
| Nonalcoholic Steatohepatitis, Hepatitis, Liver Failure, Obesity, Fatty Liver Disease | Altered Intercellular Communication | Non-alcoholic steatohepatitis (NASH) is an obesity associated common cause of liver inflammation and there are concerns that it may turn out to be the most common cause of liver failure as prevalence of obesity increases. | 26138508 |
| Inflammation, Postoperative Complications | Altered Intercellular Communication | The mechanisms linking BMI to pediatric postoperative complications are unclear, but cytokine mechanisms or changes in the response to inflammation have been postulated. | 26139160 |
| Inflammation, Endothelial dysfunction | Altered Intercellular Communication | Low-grade inflammation and endothelial dysfunction scores were computed by averaging Z-scores of six low-grade inflammation markers and four endothelial dysfunction markers respectively. | 26139210 |
| Inflammation, Endothelial dysfunction | Altered Intercellular Communication | BclI was not associated with systolic blood pressure, cIMT, low-grade inflammation, endothelial dysfunction, and prevalent CVD. | 26139210 |
| Inflammation | Altered Intercellular Communication | Senescent Vascular Smooth Muscle Cells Drive Inflammation Through an Interleukin-1a-Dependent Senescence-Associated Secretory Phenotype. | 26139463 |
| Inflammation | Altered Intercellular Communication | Whether senescent VSMCs can actively contribute to atherogenic processes, such as inflammation, is unknown. | 26139463 |
| Inflammation, Atherosclerosis | Altered Intercellular Communication | Senescent VSMCs may actively contribute toward the chronic inflammation associated with atherosclerosis through the interleukin-1a-driven senescence-associated secretory phenotype and the priming of adjacent cells to a proatherosclerotic state. | 26139463 |
| Inflammation, Atherosclerosis | Altered Intercellular Communication | These data also suggest that inhibition of this potentially important source of chronic inflammation in atherosclerosis requires blockade of interleukin-1a and not interleukin-1b. | 26139463 |
| Inflammation, Kit Ligand, human | Altered Intercellular Communication | Previous studies proposed that both inflammation, oxidative stress, and impaired endothelial dysfunction have a significant role in occurrence of slow coronary flow (SCF). | 26139836 |
| Inflammation, Chronic Kidney Diseases | Altered Intercellular Communication | monocyte-to-high density lipoprotein cholesterol ratio (MHR) is a recently emerged indicator of inflammation and oxidative stress, which have been studied only in patients with chronic kidney disease. | 26139836 |
| Inflammation, Kit Ligand, human | Altered Intercellular Communication | Higher MHR which indicates an enhanced inflammation and oxidative stress was significantly and independently associated with the presence of SCF. | 26139836 |
| Inflammation, Rheumatoid Arthritis | Altered Intercellular Communication | (18)F-FDG and (18)F-NaF PET/CT demonstrate coupling of inflammation and accelerated bone turnover in rheumatoid arthritis. | 26140472 |
| Pituitary Apoplexy, Visual disturbance | Altered Intercellular Communication | Pituitary apoplexy is a rare and potentially life-threatening disorder that is most commonly characterized by a combination of sudden headache, visual disturbance, and hypothalamic/hormonal dysfunction. | 26140487 |
| Inflammation, Tacca leontopetaloides, Metabolic Syndrome X | Altered Intercellular Communication | TIA is often associated with metabolic syndrome (causing chronic inflammation), resulting in a proinflammatory- and procoagulant-environment. | 26140921 |
| Inflammation, Anemia | Altered Intercellular Communication | Secondary outcomes included CRBSI rate, catheter patency, and biomarkers of inflammation and anemia. | 26141306 |
| Inflammatory Bowel Diseases, Inflammation | Altered Intercellular Communication | These results suggest that down-regulation of inflammation in active IBD patients might be based on the increased expression of IL-35 and IL-37. | 26141420 |
| Inflammation, Atherosclerosis | Altered Intercellular Communication | Obesity-associated inflammation and atherosclerosis might play roles in this association. | 26141694 |
| Inflammation, Atherosclerosis | Altered Intercellular Communication | Inflammation is a potential pathogenic factor for atherosclerosis and ICVA. | 26142261 |
| Inflammation, Metabolic Syndrome X | Altered Intercellular Communication | Association of metabolic syndrome with testosterone and inflammation in men. | 26142486 |
| Inflammation, Metabolic Syndrome X | Altered Intercellular Communication | Therefore, our objective was to examine the relationship between metabolic syndrome, testosterone and inflammation. | 26142486 |
| Inflammation | Altered Intercellular Communication | Subclinical inflammation might play a role in the pathophysiology of storage symptoms. | 26142598 |
| Inflammation, Chronic sinusitis, Craniosynostosis | Altered Intercellular Communication | Chronic rhinosinusitis (CRS) is a multifactorial disease of unknown cause characterized by sinonasal inflammation, increased mucus production, and defective mucociliary clearance. | 26143180 |
| Inflammation, Craniosynostosis | Altered Intercellular Communication | TH2-mediated pendrin expression is increased in NPs of patients with CRS and might lead to increased inflammation, mucus production, and decreased mucociliary clearance. | 26143180 |
| Osteomyelitis, Inflammation | Altered Intercellular Communication | Osteomyelitis is an inflammation of the bone marrow mainly caused by bacteria such as Staphylococcus aureus. | 26146361 |
| Granulomatous inflammation, Lymphoma | Altered Intercellular Communication | EBUS-TBNA results were categorized as lymphoma, specific nonlymphoma diagnosis, granulomatous inflammation, or adequate or inadequate lymphocytes with no specific diagnosis. | 26146788 |
| Granulomatous inflammation, Lymphoma | Altered Intercellular Communication | Granulomatous inflammation diagnosed on the basis of EBUS-TBNA was associated with a low likelihood of lymphoma being present (likelihood ratio, 0.00; 95% confidence interval [CI], 0.00-0.276). | 26146788 |
| Inflammation, Neoplasms | Altered Intercellular Communication | The NLRP3 inflammasome complex, an important regulatory factor of inflammation and cell apoptosis, has attracted considerable attention in the development of tumor. | 26146985 |
| Inflammation, Pathology | Altered Intercellular Communication | Thus, rapamycin might ameliorate age-related pathologies, including late-life cancer, by suppressing senescence-associated inflammation. | 26147250 |
| Heart Diseases, Inflammation, "Dents disease | Altered Intercellular Communication | IFG was an intermediary condition for heart disease, inflammation, and oxidative stress in elderly adults but not for 2-year incident disease or all-cause mortality. | 26147402 |
| Inflammation, Calcinosis | Altered Intercellular Communication | Active calcification and inflammation of the carotid atheroma were assessed and compared in symptomatic and asymptomatic plaques by 18F-NaF and 18F-FDG PET/CT. | 26147617 |
| Inflammation, Calcinosis | Altered Intercellular Communication | Active calcification and inflammation are simultaneous processes in the symptomatic and asymptomatic carotid atheroma. | 26147617 |
| Inflammation, Calcinosis | Altered Intercellular Communication | However, active calcification seems predominant over inflammation in both groups. | 26147617 |
| Inflammatory disorder, Gout | Altered Intercellular Communication | Gout is a common inflammation disease resulting from an increase in serum uric acid. | 26147675 |
| Inflammation, Breast Carcinoma, Necrosis | Altered Intercellular Communication | Inflammation and cell necrosis are one of the consequences that accompany breast cancer. | 26148597 |
| Inflammation, Necrosis | Altered Intercellular Communication | However, inflammation and cell necrosis are well known to be involved in stimulation of cellular and humeral immunity. | 26148597 |
| Inflammation, Glomerulonephritis, Vasculitis, CTCAE | Altered Intercellular Communication | ANCA vasculitis encompasses several autoimmune conditions characterised by destruction of small vessels, inflammation of the respiratory tract and glomerulonephritis. | 26149790 |
| ARCN1 gene, Inflammation | Altered Intercellular Communication | Non-anaemic iron deficiency is common in COPD and appears to be driven by inflammation. | 26150144 |
| Arthralgia, Inflammation | Altered Intercellular Communication | The remaining 88.4% of ultrasound examinations performed in 2011 were intended to investigate inflammation in 25.8%, differential diagnosis of arthralgia in 17.1%, enthesis in 12.6% and temporal arteries in 17.3%, and to conduct ultrasound-guided procedures in 10.6% and study microcrystalline pathologies in 4.7%. | 26150268 |
| Inflammation, Pleural effusion disorder, Anemia, Hypoalbuminemia | Altered Intercellular Communication | Larger bilateral pleural effusions in patients with ABAD were associated with hypoalbuminaemia and potentially with anaemia and inflammation, and may increase the length of intensive care unit stay. | 26150676 |
| Chronic Obstructive Airway Disease | Altered Intercellular Communication | Effect on Proline-Glycine-Proline and Neutrophilic Inflammation in Chronic Obstructive Pulmonary Disease. | 26151090 |
| ARCN1 gene, Inflammation | Altered Intercellular Communication | The self-propagating acetyl-proline-glycine-proline (AcPGP) pathway is a novel means of neutrophilic inflammation that is pathologic in the development of COPD. | 26151090 |
| Pneumonitis | Altered Intercellular Communication | Roflumilast reduces pulmonary inflammation through decreasing prolyl endopeptidase activity and AcPGP. | 26151090 |
| Communicable Diseases, Unknown (origin) (qualifier value) | Altered Intercellular Communication | It can be secondary to an inflammatory condition or infectious disease, however many cases of onychodystrophy are idiopathic in nature. | 26151794 |
| ARCN1 gene, Inflammation, Asthma | Altered Intercellular Communication | The inflammation of asthma typically is different than that of COPD, and the degree of inflammation and cellular damage varies with asthma severity. | 26152317 |
| Edematous skin, Lichen Sclerosus et Atrophicus, Waldenstrom Macroglobulinemia | Altered Intercellular Communication | The classic histopathologic features of lichen sclerosus et atrophicus (LS) include lymphoplasmacytic inflammation below a zone of dermal edema and sclerosis. | 26152335 |
| Inflammation | Altered Intercellular Communication | Trace elements are essential for the functioning of different processes in the body, including the immune system and associated responses to infection/inflammation. | 26152852 |
| Inflammation, Thoracic aortic dissection | Altered Intercellular Communication | Because inflammation may be part of the pathogenesis of thoracic aortic dissection, we investigated whether trace element changes associated with inflammation occur in serum and tissue samples during the disease. | 26152852 |
| Inflammation | Altered Intercellular Communication | The Cu/Zn ratio in the serum, a marker of infection/inflammation, did not change in the patients. | 26152852 |
| Inflammation, Thoracic aortic dissection | Altered Intercellular Communication | Concerning trace element changes in the serum and tissue, our data do not support the hypothesis that inflammation is involved in the pathogenesis of thoracic aortic dissection. | 26152852 |
| Sepsis, Inflammation | Altered Intercellular Communication | Expression of CD11c and EMR2 on neutrophils: potential diagnostic biomarkers for sepsis and systemic inflammation. | 26153037 |
| Inflammation, Carcinoma of lung, Hamartoma | Altered Intercellular Communication | The (18)F-alfatide RGD PET/CT analysis correctly recognized 17 patients with lung cancer, 4 patients (hamartoma) as true negative, and 5 patients (4 chronic inflammation and 1 inflammatory pseudotumour) as false positive. | 26153145 |
| Inflammation, Diabetes Mellitus, Non-Insulin-Dependent | Altered Intercellular Communication | Association of subclinical inflammation with deterioration of glycaemia before the diagnosis of type 2 diabetes: the KORA S4/F4 study. | 26155746 |
| Inflammation, Diabetes Mellitus | Altered Intercellular Communication | The role of biomarkers of subclinical inflammation in the early deterioration of glycaemia before type 2 diabetes is largely unknown. | 26155746 |
| Inflammation | Altered Intercellular Communication | T-wave axis deviation is associated with biomarkers of low-grade inflammation. | 26155907 |
| Inflammation | Altered Intercellular Communication | These results suggest that a low-grade inflammation likely contributes to the pathogenesis of T- wave axis deviation. | 26155907 |
| Inflammation, Ischemic stroke | Altered Intercellular Communication | Evidence is emerging that inflammation plays a key role in the pathophysiology of ischemic stroke (IS). | 26156202 |
| Communicable Diseases, Inflammation | Altered Intercellular Communication | TIB pattern reflects endobronchiolar inflammation due mainly but not exclusively to an infectious cause. | 26156310 |
| Diabetes Mellitus, Non-Insulin-Dependent | Altered Intercellular Communication | Inflammation-associated declines in cerebral vasoreactivity and cognition in type 2 diabetes. | 26156513 |
| Inflammation, Executive Function | Altered Intercellular Communication | Inflammation may further impair cerebral vasoregulation, which consequently accelerates decline in executive function and daily activities performance in older people with T2DM. | 26156513 |
| Inflammation, Primary malignant neoplasm | Altered Intercellular Communication | We identified markers of inflammation in VAT, which supports prior evidence regarding the role of visceral adiposity and cancer. | 26156741 |
| Inflammation, ELN gene | Altered Intercellular Communication | As ELN correlates with the degree of tissue inflammation, we investigated whether ELN was associated with specific cytokine profiles. | 26156866 |
| Organ Dysfunction Scores, Obesity, Fatty infiltration | Altered Intercellular Communication | Obesity is a chronic inflammatory condition and is strongly linked to raised levels of pro-inflammatory factors and may lead to fatty infiltration of multiple internal organs including the gallbladder and liver, causing organ dysfunction. | 26158139 |
| Inflammation | Altered Intercellular Communication | For each eye, the grader documented the presence or absence of follicular trachoma (TF) and intense trachomatous inflammation (TI) according to the WHO simplified grading system. | 26158573 |
| Follicle, Inflammation, Tissue Factor | Altered Intercellular Communication | A 2-stage cluster-random sampling design selected 30 households from each of 30 clusters per evaluation unit; all residents aged 1 year and older in selected households were examined for evidence of follicular trachoma (TF), intense trachomatous inflammation (TI), and trachomatous trichiasis (TT). | 26158575 |
| Airway structure | Altered Intercellular Communication | Interleukin-33 promotes inflammatory cytokine production in chronic airway inflammation. | 26158865 |
| Airway structure, ARCN1 gene | Altered Intercellular Communication | Its role in chronic airway inflammation that develops into COPD is widely unknown. | 26158865 |
| Airway structure, ARCN1 gene | Altered Intercellular Communication | Thus, the IL-33 is a promoter of chronic airway inflammation that contributes to COPD development. | 26158865 |
| Inflammation, Data types - Address | Altered Intercellular Communication | Monocytes are involved in inflammation in AD and are recruited to the diseased brain. | 26159193 |
| Inflammation, Eosinophilic esophagitis, Inflammatory disorder, Esophageal Diseases, "Extra-osseous Ewings sarcoma | Altered Intercellular Communication | Eosinophilic esophagitis (EoE) is an inflammatory immune-mediated disease with predominant eosinophilic inflammation characterized by the presence of esophageal dysfunction symptoms. | 26159479 |
| vascular inflammations | Altered Intercellular Communication | The detection of vascular inflammation had an important impact, and led to a change of treatment in a high percentage of patients with LVV. | 26159505 |
| Inflammation | Altered Intercellular Communication | Although his laboratory data were indicative of severe inflammation, an abdominal examination and a computed tomography (CT) scan did not produce any significant findings. | 26160462 |
| Inflammation, Chronic Kidney Diseases | Altered Intercellular Communication | Iron Status and Inflammation in Early Stages of Chronic Kidney Disease. | 26160488 |
| Inflammation, Anemia | Altered Intercellular Communication | Novel biomarkers of iron metabolism might be useful to distinguish iron deficiency anemia connected with inflammation and absolute iron deficiency. | 26160488 |
| Inflammation, Blood Vessel, Chronic Kidney Diseases | Altered Intercellular Communication | Molecular pathway analysis confirmed the modification of known processes involved in CKD complications, including decreased haemostasis and increased inflammation, complement activation and vascular damage. | 26160894 |
| Sepsis, Inflammation | Altered Intercellular Communication | Measurement of circulating levels of the histone H3 provides additional information to that of the conventional indicators of inflammation for determining the severity of sepsis. | 26161427 |
| Inflammation, Fracture | Altered Intercellular Communication | Chronic inflammation may increase the risk of fracture, and omega-3 polyunsaturated fatty acids (PUFAs) may reduce fracture risk via down-regulation of inflammatory cytokine gene expression and other mechanisms. | 26161450 |
| Inflammation, Fracture | Altered Intercellular Communication | The odds ratio of hip fracture comparing the highest to lowest quartiles was 2.24 (95% confidence interval, 1.05-4.79; P for linear trend, .048) for TNFa-sR1 and 2.83 (95% confidence interval, 1.34-5.99; P for linear trend, .011) for TNFa-sR2, adjusted for FRAX hip fracture score, nutritional variables, and selected factors impacting inflammation; there was a gradient of risk by increasing quartile in TNFa-sR1. | 26161450 |
| Inflammation, Helicobacter pylori, Duodenal Diseases | Altered Intercellular Communication | The goal of this study was to analyze the role of Toll-like receptor 4 polymorphisms +896 (rs4986790) and +1196 (rs4986791) in the pathogenesis of Helicobacter pylori related gastroduodenal diseases in relation to gastric secretion and inflammation. | 26161647 |
| Gastritis | Altered Intercellular Communication | Toll-like receptor 4 genotypes did not show any association with Helicobacter pylori positivity or the features of gastric inflammation. | 26161647 |
| Communicable Diseases, Inflammation | Altered Intercellular Communication | In the aftermath of an ocular bee sting, close surveillance for inflammation and infection is essential. | 26161915 |
| prostatitis | Altered Intercellular Communication | PHI was the only determinant for prostatitis vs. BPH, whereas no biomarkers could differentiate prostate inflammation from HG-PIN. | 26162485 |
| vascular inflammations, Inflammatory disorder, Atherosclerosis | Altered Intercellular Communication | Atherosclerosis is considered to be a systemic vascular inflammatory disease, and oxidative stress is known to be a contributor to vascular inflammation. | 26162942 |
| vascular inflammations | Altered Intercellular Communication | Vascular inflammation and oxidative stress are associated with the presence of ELC. | 26162942 |
| Inflammation, Intervertebral Disc Degeneration, Pain Distress Question | Altered Intercellular Communication | Our current study strongly demonstrates the potential of TSA for the treatment of inflammation and followed pain in degenerative disc disease. | 26163178 |
| Inflammation | Altered Intercellular Communication | In several studies, exposure to fine particulate matter (PM) has been associated with inflammation, with inconsistent results. | 26163546 |
| Necrotizing granulomatous inflammation, Mycobacterium Infections, Tuberculosis | Altered Intercellular Communication | Our aim was to determine the clinical usefulness of PCR for differential diagnosis of tuberculosis and nontuberculous mycobacterial infection in lung tissue that show chronic granulomatous inflammation. | 26163897 |
| Aortic Diseases, Aortic Aneurysm, Lupus Erythematosus | Altered Intercellular Communication | In patients with a history of systemic lupus erythematosus, with or without active inflammation, screening for aortic disease should be selectively performed if other risk factors for aortic aneurysm are present. | 26164362 |
| Inflammation, Chronic Obstructive Airway Disease, hepcidin, Exacerbation | Altered Intercellular Communication | Systemic inflammation up-regulates serum hepcidin in exacerbations and stabile chronic obstructive pulmonary disease. | 26164540 |
| Inflammation, Hypoxia | Altered Intercellular Communication | Hepcidin is the main regulator of systemic iron homeostasis and its expression is modulated by iron status, hypoxia, erythroid factors and inflammation. | 26164540 |
| ARCN1 gene, Inflammation, Hypoxia, Exacerbation, hepcidin | Altered Intercellular Communication | The aim of our study was to examine a relationship between level of hepcidin and iron status, erythropoietic activity, hypoxia and inflammation in exacerbations and stable COPD patients. | 26164540 |
| ARCN1 gene, Inflammation, Hypoxia, hepcidin | Altered Intercellular Communication | We hypothesized that hepcidin concentration is changed in COPD patients and is substantially influenced by inflammation and/or hypoxia. | 26164540 |
| ARCN1 gene, Inflammation, Exacerbation | Altered Intercellular Communication | Systemic inflammation and elevated values of IL-6 present in exacerbations and stabile COPD might be responsible for the observed increased hepcidin level. | 26164540 |
| Coronary Arteriosclerosis | Altered Intercellular Communication | Immunoglobulin G4 (IgG4)-related immuno-inflammation has been suggested to affect the development of coronary artery atherosclerosis. | 26164687 |
| Dental Plaque | Altered Intercellular Communication | Serum IgG4 concentrations were significantly associated with NCP, especially with LDP, suggesting that IgG4-related immuno-inflammation may play a role in coronary plaque vulnerability. | 26164687 |
| Inflammation, Cellulitis, Erythema, Swelling, Skin Infection, CTCAE | Altered Intercellular Communication | In the very next day, initial signs of skin infection appeared including local inflammation, erythema, swelling and cellulitis restricted to saphenectomy site. | 26165059 |
| Prostate, Atrophic, Acute and chronic inflammation | Altered Intercellular Communication | Patients with atrophy were older and had a larger prostate, and more acute and chronic prostate inflammation. | 26165588 |
| Gingivitis, Dental Plaque, Periodontal Route of Administration | Altered Intercellular Communication | No periodontal destruction, signs of gingival inflammation or increased plaque accumulation was observed. | 26165864 |
| ARCN1 gene, Chronic Obstructive Airway Disease, Bronchiolitis | Altered Intercellular Communication | Inflammation of the small airways (bronchiolitis) contributes to airflow limitation by narrowing and obliterating the airway lumen in patients with chronic obstructive pulmonary disease (COPD). | 26165891 |
| vascular inflammations | Altered Intercellular Communication | CD4+CD25+FOXP3+ regulatory T cells (Tregs) play a role in the modulation of vascular inflammation. | 26166019 |
| Pancreatic Diseases, Pancreatitis | Altered Intercellular Communication | Acute pancreatitis (AP) is the most common pancreatic disease and consists of an acute inflammation of the pancreas. | 26166112 |
| Kidney Failure, Chronic, Inflammation, Endothelial dysfunction, Cerebral Atherosclerosis | Altered Intercellular Communication | Inflammation, which initiates endothelial dysfunction, vascular atherosclerosis, and oxidative stress, may negatively influence renal function and accelerate the development of end-stage renal disease (ESRD). | 26166123 |
| Inflammation, Congenital Abnormality, Communicable Diseases, Head Injuries, Penetrating, Facial paralysis, Infiltration | Altered Intercellular Communication | Bilateral facial nerve palsy may result from cranial trauma, congenital abnormalities, inflammation, infiltration, or infection, but is rarely associated with syphilis. | 26166431 |
| Refractory anemias, Cartilage destruction, Autoimmune Diseases, Rheumatoid Arthritis, Abnormal inflammatory response | Altered Intercellular Communication | Rheumatoid arthritis (RA) is a chronic autoimmune disease characterized by abnormal inflammation, angiogenesis, and cartilage destruction. | 26166764 |
| Inflammation, Carcinoma of lung | Altered Intercellular Communication | It is also suggested that TB predicts raised lung cancer risk likely related to chronic inflammation in the lungs. | 26166791 |
| Inflammation, Neoplasms | Altered Intercellular Communication | In two patients, routine inspection was unable to discern whether the lesions were inflammation or tumors. | 26167082 |
| Inflammation, Impaired cognition, diabetic, Bipolar Disorder | Altered Intercellular Communication | Serum Soluble Adhesion Molecules and Markers of Systemic Inflammation in Elderly Diabetic Patients with Mild Cognitive Impairment and Depressive Symptoms. | 26167502 |
| Inflammation, millicurie, Depressed mood, diabetic | Altered Intercellular Communication | We first demonstrated that elderly diabetic patients with MCI, particularly those with depressive mood have higher levels of soluble adhesion molecules and markers of low-grade systemic inflammation. | 26167502 |
| Peripheral Neuropathy, Inflammation, Chemical injury | Altered Intercellular Communication | Non-systemic vasculitic peripheral neuropathy is a rare condition characterized by necrotizing inflammation resulting in luminal narrowing of the vasa nervorum, leading to ischemic injury to peripheral nerves. | 26167722 |
| Inflammation, Pain Distress Question | Altered Intercellular Communication | Elevated markers of inflammation in the absence of a possible explanation should prompt the clinician to perform a nerve biopsy; however, it is an invasive procedure and is associated with complications of post-neuropathic pain and delayed wound healing. | 26167722 |
| Inflammation, Intestinal Mucosa | Altered Intercellular Communication | We showed a correlation between secreted IFN-g/IL-18 levels, and caspase-1 activation, with inflammation intensity of intestinal CD mucosa explants. | 26168332 |
| Multiple Myeloma, Inflammation | Altered Intercellular Communication | Interrelationship between angiogenesis, inflammation and oxidative stress in Indian patients with multiple myeloma. | 26169214 |
| Inflammation, Infectious Lung Disorder, Bronchiectasis, Chronic disease | Altered Intercellular Communication | Bronchiectasis is a chronic disorder characterised by permanent and irreversible abnormal dilation of the bronchi and bronchioles, primarily caused by repeated cycles of pulmonary infections and inflammation, which lead to reduced mucociliary clearance and to the excessive production of sputum. | 26169808 |
| Inflammation, Primary malignant neoplasm | Altered Intercellular Communication | Prostaglandins are a group of lipid compounds involved in inflammation and cancer. | 26170067 |
| Inflammation, "Alzheimers Disease", Data types - Address | Altered Intercellular Communication | Inflammation is a well-defined factor in Alzheimer's disease (AD). | 26170148 |
| Benign prostatic hypertrophy | Altered Intercellular Communication | Benign prostatic hyperplasia is one of the chronic inflammatory conditions in ageing male populations. | 26172054 |
| Inflammation, Hypersensitivity, Abnormal digestive tract function, Intestinal infectious disease (disorder) | Altered Intercellular Communication | Etiological factors include gastrointestinal peristalsis disturbances, visceral hypersensitivity, chronic inflammation of the mucous membrane, dysbacteremia, intestinal infections, psychosomatic and nutritional factors. | 26172165 |
| Sepsis, Inflammation | Altered Intercellular Communication | His general shape was severe, abdomen was tender at palpation in hypogastrium, peritoneal signs were positive, and blood tests showed highly elevated markers of inflammation, including procalcitonin, what suggested the sepsis. | 26172168 |
| Tumor necrosis, Inflammation, Vasogenic Edema, Necrosis | Altered Intercellular Communication | Coexpression of Sur1 and Trpm4 in necrotic endothelial cells was also associated with vasogenic edema indicated by upregulated perivascular tumor necrosis factor, extravasation of serum immunoglobulin G, and associated inflammation. | 26172285 |
| Inflammation | Altered Intercellular Communication | There was also no evidence of reduced indicators of inflammation or oxidative stress. | 26172395 |
| Asbestos-Related Lung Disorder, Pneumonitis | Altered Intercellular Communication | Further studies should determine the conditions required to increase levels of total anti-oxidant capacity in the blood and in the lungs of subjects with either asbestos-related diseases or subclinical lung inflammation. | 26172395 |
| Migraine Disorders | Altered Intercellular Communication | During development, hormonal changes may act on predetermined brain circuits, increasing the probability of migraine. | 26172552 |
| Crohn Disease, Inflammation | Altered Intercellular Communication | Clinical remission was defined as Crohn's Disease Activity Index (CDAI) < 150 and endoscopic remission as CDAI < 150 + absence of mucosal lesions + no signs of active inflammation on ileocolonoscopy. | 26173493 |
| Inflammation, alpha 1-Antitrypsin Deficiency | Altered Intercellular Communication | Alpha-1 antitrypsin (AAT) encoded by SERPINA1 is an acute-phase inflammation marker, and AAT deficiency (AATD) is known as one of the common genetic disorders in European populations. | 26174136 |
| Airway structure | Altered Intercellular Communication | Fraction of exhaled nitric oxide (FeNO) is a marker of eosinophilic airway inflammation. | 26174797 |
| Inflammation, Unspecified visual loss | Altered Intercellular Communication | In all three cases, the cause of inflammation was not clear from clinical examination alone and prompt treatment was required to prevent permanent vision loss. | 26174811 |
| Inflammation, Ischemic stroke | Altered Intercellular Communication | Immune responses and inflammation play an important role in the pathogenesis of ischemic stroke. | 26175305 |
| Inflammation, Thrombosis | Altered Intercellular Communication | The thrombosis probably resulted from inflammation in the adjacent diverticulum. | 26176578 |
| Inflammation, Sarcopenia, Obesity | Altered Intercellular Communication | Research suggests that inflammation has an important role in the pathogenesis of obesity and sarcopenia. | 26177029 |
| Inflammation, VITILIGO-ASSOCIATED MULTIPLE AUTOIMMUNE DISEASE SUSCEPTIBILITY 1 (finding) | Altered Intercellular Communication | Association of Angiotensin-Converting Enzyme (ACE) Gene Polymorphism with Inflammation and Cellular Cytotoxicity in Vitiligo Patients. | 26177100 |
| Inflammation | Altered Intercellular Communication | Angiotensin converting enzyme (ACE) plays an important role in the physiology of the vasculature, blood pressure and inflammation. | 26177100 |
| Neurodegenerative Disorders, Inflammation, Parkinson Disease, "Alzheimers Disease", Neurotoxicity Syndromes, Acute kidney injury, Mental disorders | Altered Intercellular Communication | Brain inflammation results after both acute injury and also with the appearance of mutated proteins or endogenous neurotoxic metabolites associated with slow neurodegenerative diseases such as Alzheimer's and Parkinson's diseases and some psychiatric disorders. | 26177578 |
| Inflammation | Altered Intercellular Communication | Microglia play a key role in brain inflammation by the release of pro-inflammatory cytokines and with ageing, microglia exhibit 'priming' leading to increased basal release of the pro-inflammatory cytokines. | 26177578 |
| Inflammation, Infection | Altered Intercellular Communication | Preliminary Outcomes of Distal IMAP and SEAP Flaps for the Treatment of Unstable Keloids Subject to Recurrent Inflammation and Infections in the Lower Sternal and Upper Abdominal Areas. | 26177690 |
| Inflammation, Neoplasms, Necrosis, Vascular Invasion Assessment, Ulceration, CTCAE | Altered Intercellular Communication | During the pathological process histologic subtype, Breslow thickness and Clark level, tumor cell type, mitotic rate, peritumoral inflammation, as well as ulceration, regression, necrosis, vascular invasion and presence of satellite were analyzed and related to clinical data. | 26177701 |
| Airway structure | Altered Intercellular Communication | There were also no significant changes in bacterial load measured by 16S qPCR or in airway inflammation. | 26179246 |
| Parkinson Disease, Aggregation, palladium, Colitis | Altered Intercellular Communication | We showed that Parkinson's disease (PD) patients have alpha-synuclein (a-Syn) aggregation in their colon with evidence of colonic inflammation. | 26179554 |
| palladium, Dysbiosis | Altered Intercellular Communication | This report provides evidence that proinflammatory dysbiosis is present in PD patients and could trigger inflammation-induced misfolding of a-Syn and development of PD pathology. | 26179554 |
| parathyroid hormone secretion, Hyperparathyroidism, Primary | Altered Intercellular Communication | Primary hyperparathyroidism is an endocrinopathic condition characterized by hypersecretion of parathyroid hormone. | 26179753 |
| Inflammation, "Alzheimers Disease | Altered Intercellular Communication | Amyloid precursor protein metabolism and inflammation markers in preclinical Alzheimer disease. | 26180139 |
| Inflammation, Data types - Address, Nerve Degeneration | Altered Intercellular Communication | Our findings suggest that inflammation in the CNS increases in normal aging and is intimately related to markers of neurodegeneration in the preclinical stages of AD and SNAP. | 26180139 |
| Inflammation, Overweight | Altered Intercellular Communication | a-Galacto-oligosaccharides Dose-Dependently Reduce Appetite and Decrease Inflammation in Overweight Adults. | 26180243 |
| Inflammation, Overweight | Altered Intercellular Communication | Consumption of a-GOSs for 14 d dose-dependently reduced appetite, food intake, and inflammation in overweight adults with no impact of a-GOS composition. | 26180243 |
| Inflammation, Spinal Cord Injuries | Altered Intercellular Communication | Cross-sectional associations of pulmonary function with systemic inflammation and oxidative stress in individuals with chronic spinal cord injury. | 26180939 |
| Inflammation | Altered Intercellular Communication | Systemic inflammation, and to a lesser extent oxidative stress, have been associated with reduced pulmonary function. | 26180939 |
| Inflammation, Spinal Cord Injuries, Stanford Cancer Institute | Altered Intercellular Communication | Our objective was to evaluate the associations between biomarkers of inflammation (C-reactive protein (CRP), interleukin-6 (IL-6)) and novel makers of global oxidative stress (fluorescent oxidation products (FLOx)) with spirometric and lung volume measures in individuals with chronic spinal cord injury (SCI). | 26180939 |
| Inflammation | Altered Intercellular Communication | Increased systemic inflammation was associated with reductions in FEV1 and FVC independent of a number of covariates. | 26180939 |
| Inflammation, Pulmonary function tests, Stanford Cancer Institute | Altered Intercellular Communication | Although the mechanism is uncertain, these results suggest that reductions in pulmonary function in SCI are associated with systemic inflammation. | 26180939 |
| Inflammation, Cardiovascular Diseases | Altered Intercellular Communication | Persons living with HIV are at increased risk for cardiovascular disease in part because of persistent inflammation and coagulation activation. | 26181818 |
| Inflammation, Malnutrition, Anemia | Altered Intercellular Communication | A cohort of 212 hemodialysis patients free of overt inflammation or malnutrition, were treated for anemia with parenteral iron-sucrose and an erythropoesis-stimulating agent, in keeping with current clinical guidelines. | 26182077 |
| Inflammation, Hemolysis (biological function) | Altered Intercellular Communication | However, days of storage duration poorly correlated (R(2) <0.10) with all measured indicators of hemolysis and inflammation. | 26183122 |
| Inflammation, Fibrosis Assessment | Altered Intercellular Communication | Weekly body mass index (BMI), histopathological examination and quantitative real-time PCR analysis on genes involved in lipid metabolism, inflammation and fibrosis were performed. | 26183212 |
| Inflammation, precancerous lesions, Pancreatitis, Chronic | Altered Intercellular Communication | As chronic inflammation has been recently demonstrated to promote dissemination of in situ precancerous lesions, we investigated the prognostic significance of PanINs associated with chronic pancreatitis (CP) in PDAC patients. | 26183380 |
| Inflammation | Altered Intercellular Communication | PanIN-3 in association with CP is a significant prognostic factor for decreased survival in PDAC patients, suggesting that chronic inflammation may accelerate the progression of preinvasive high-grade PanIN. | 26183380 |
| Granuloma | Altered Intercellular Communication | Previous reports have mentioned that pyogenic granulomas in the oral cavity were associated with the female hormonal receptor, vascular endothelial growth factor, and proliferative immune markers; however, no significant staining was observed in our patient. | 26184018 |
| Inflammation, Hepatitis | Altered Intercellular Communication | A liver biopsy demonstrated heavy portal tract inflammation, associated interface hepatitis, and numerous necroinflammatory foci throughout the liver parenchyma. | 26184021 |
| Inflammation, Acromion, Bursitis | Altered Intercellular Communication | Subacromial bursitis is caused by inflammation of the bursa that separates the superior surface of the supraspinatus tendon from the overlying coraco-acromial ligament and acromion. | 26184525 |
| Prostate carcinoma, Neoplasms, prostatitis | Altered Intercellular Communication | Chronic baseline prostate inflammation is associated with lower tumor volume in men with prostate cancer on repeat biopsy: Results from the REDUCE study. | 26184556 |
| Prostate carcinoma, prostatitis | Altered Intercellular Communication | To evaluate whether baseline acute and chronic prostate inflammation among men with initial negative biopsy for prostate cancer (PC) is associated with PC volume at the 2-year repeat prostate biopsy in a clinical trial with systematic biopsies. | 26184556 |
| Inflammation, Neoplasms | Altered Intercellular Communication | Acute and chronic inflammation and tumor volume were determined by central pathology. | 26184556 |
| Inflammation | Altered Intercellular Communication | Acute and chronic inflammation were significantly associated with each other (P < 0.001). | 26184556 |
| Inflammation | Altered Intercellular Communication | Chronic inflammation was associated with larger prostate (P < 0.001) and lower pre-repeat biopsy PSA (P = 0.01). | 26184556 |
| Inflammation, Neoplasms | Altered Intercellular Communication | At 2-year biopsy, baseline chronic inflammation was associated with lower mean tumor volume (2.07 ul vs. 3.15 ul; P = 0.001), number of biopsy cores involved (1.78 vs. 2.19; P < 0.001), percent of cores involved (17.8% vs. 22.8%; P < 0.001), core involvement (0.21 ul vs. 0.31 ul; P < 0.001), and overall percent tumor involvement (1.40% vs. 2.01%; P < 0.001). | 26184556 |
| Inflammation, Neoplasms | Altered Intercellular Communication | Baseline acute inflammation was not associated with any tumor volume measurement. | 26184556 |
| Inflammation | Altered Intercellular Communication | In a cohort of men with 2-year repeat prostate biopsy positive for PC after a negative baseline biopsy, baseline chronic inflammation was associated with lower PC volume. | 26184556 |
| Inflammation, Postmenopausal state, Breast Carcinoma, Obesity | Altered Intercellular Communication | Adipokines and inflammation may provide a mechanistic link between obesity and postmenopausal breast cancer, yet epidemiologic data on their associations with breast cancer risk are limited. | 26185195 |
| Granuloma, Ulcerative Colitis | Altered Intercellular Communication | Ulcerative colitis (UC) is defined as a chronic inflammatory condition causing continuous mucosal inflammation of the colon without granulomas on biopsy. | 26185880 |
| Granuloma, Ulcerative Colitis | Altered Intercellular Communication | Ulcerative colitis (UC) is defined as a chronic inflammatory condition causing continuous mucosal inflammation of the colon without granulomas on biopsy. | 26185880 |
| Inflammation, Neoplasms | Altered Intercellular Communication | This chronic inflammation may lead to a modest increase in neoplasia risk. | 26185881 |
| Heart Diseases, Depressive disorder, Chronic heart failure, Depression, CTCAE | Altered Intercellular Communication | Inflammation Markers and Major Depressive Disorder in Patients With Chronic Heart Failure: Results From the Sertraline Against Depression and Heart Disease in Chronic Heart Failure Study. | 26186432 |
| Inflammation, Depressive disorder, Congestive heart failure, Minimal Disseminated Disease, Chronic heart failure | Altered Intercellular Communication | Major depressive disorder (MDD) and chronic heart failure (CHF) have in common heightening states of inflammation, manifested by elevated inflammation markers such as C-reactive protein. | 26186432 |
| Minimal Disseminated Disease, Inflammation, Depression, CTCAE, Congestive heart failure | Altered Intercellular Communication | MDD in patients with CHF was associated with altered inflammation marker levels compared with patients with CHF who had no depression. | 26186432 |
| Inflammation, polychondritis | Altered Intercellular Communication | Relapsing polychondritis is a rare disease characterized by cartilage inflammation. | 26187053 |
| Inflammation | Altered Intercellular Communication | Younger African-Americans initially had the highest GFR but showed a steep age-related decrement that was associated with elevated inflammation. | 26187318 |
| Perihilar Cholangiocarcinoma | Altered Intercellular Communication | Evaluation of inflammation-based prognostic scores in patients undergoing hepatobiliary resection for perihilar cholangiocarcinoma. | 26187429 |
| Primary malignant neoplasm | Altered Intercellular Communication | Inflammation-based prognostic scores have prognostic value in several kinds of cancer. | 26187429 |
| Perihilar Cholangiocarcinoma | Altered Intercellular Communication | We evaluated whether inflammation-based prognostic scores are associated with survival of patients with perihilar cholangiocarcinoma. | 26187429 |
| Perihilar Cholangiocarcinoma | Altered Intercellular Communication | Inflammation-based scores (i.e., the modified Glasgow Prognostic Score (mGPS), neutrophil-lymphocyte ratio, platelet-lymphocyte ratio, and prognostic nutritional index) were retrospectively evaluated in 534 patients who underwent resection for perihilar cholangiocarcinoma. | 26187429 |
| Inflammation, Fracture, Osteopenia | Altered Intercellular Communication | Low grade inflammation is associated with lower velocity of sound and broadband ultrasound attenuation in older men, but not with bone loss or fracture risk in a longitudinal aging study. | 26188108 |
| Bone Density, Inflammation, Fracture | Altered Intercellular Communication | Our objective was to investigate whether low grade systemic inflammation was associated with bone markers, bone quality, bone mass and fracture risk in a population of older persons. | 26188108 |
| Inflammation, Vitality | Altered Intercellular Communication | Transcriptomic and epigenetic analyses reveal a gender difference in aging-associated inflammation: the Vitality 90+ study. | 26188803 |
| Malignant neoplasm of esophagus, Inflammation | Altered Intercellular Communication | Diet-related inflammation and oesophageal cancer by histological type: a nationwide case-control study in Sweden. | 26189130 |
| Malignant neoplasm of esophagus, Inflammation | Altered Intercellular Communication | This project sought to test the role of diet-related inflammation in modulating the risk of oesophageal cancer. | 26189130 |
| Malignant neoplasm of esophagus, Inflammation | Altered Intercellular Communication | Diet-related inflammation appears to be associated with an increased risk of oesophageal cancer, regardless of histological type. | 26189130 |
| Degenerative polyarthritis, Inflammation | Altered Intercellular Communication | Local inflammation plays a role in the pathophysiology of osteoarthritis (OA) and chemokines exert catabolic effects on articular cartilage either through paracrine and/or autocrine mechanisms. | 26189947 |
| Inflammation, Lupus Nephritis | Altered Intercellular Communication | Glomerular deposition of immune complexes and inflammation induce podocyte injury in lupus nephritis (LN). | 26191151 |
| Primary malignant neoplasm | Altered Intercellular Communication | There is increasing evidence that the presence of an inflammation-based prognostic score (modified Glasgow prognostic score, mGPS) could predict survival in patients with advanced cancer. | 26191228 |
| Autoimmune necrotizing myopathy, Inflammation, Necrosis | Altered Intercellular Communication | Necrotizing autoimmune myopathy (NAM) is characterized pathologically by necrotic muscle fibers with absent or minimal inflammation. | 26192196 |
| Inflammation, Prostate carcinoma, Benign prostatic hypertrophy, Prostatic Intraepithelial Neoplasias, Atrophic | Altered Intercellular Communication | Computer-identified features for each of the noncancerous disease categories (eg, benign prostatic hyperplasia [BPH], prostatic intraepithelial neoplasia [PIN], inflammation, and atrophy) and prostate cancer were extracted. | 26192734 |
| Inflammation, Primary malignant neoplasm, Atrophic | Altered Intercellular Communication | The focal appearance of lesions on dynamic contrast-enhanced images may help discriminate atrophy and inflammation from cancer. | 26192734 |
| Inflammation, Sarcoidosis | Altered Intercellular Communication | Sarcoidosis is a systemic disease characterized by noncaseating granulomatous inflammation with tremendous clinical heterogeneity and uncertain pathobiology and lacking in clinically useful biomarkers. | 26193069 |
| Inflammation, Periodontitis, Tooth structure, Premature tooth loss | Altered Intercellular Communication | Progressing as a chronic inflammation at the level of tooth support tissues, untreated chronic periodontitis may lead to a premature loss of the dental organ. | 26193206 |
| Hepatitis A, Inflammation, Fibrosis Assessment, Necrosis | Altered Intercellular Communication | The percutaneous liver biopsy performed on the patients with chronic viral hepatitis C showed a series of histological alterations, the most frequent being: portal inflammation, periportal necrosis, lobular inflammation, focal necrosis, and hepatic fibrosis (scarring). | 26193211 |
| Squamous cell carcinoma, Ulcerative inflammation | Altered Intercellular Communication | The first lesion appeared in 2003, it was excised and the histopathological result showed squamous cell carcinoma with undifferentiated areas and chronic ulcerative inflammation. | 26193225 |
| Vulvar Lichen Sclerosus, Ulcerative inflammation | Altered Intercellular Communication | The patient underwent radiation therapy remaining at the end of it a small-ulcerated lesion at the superior vulvar commissure, which was biopsied in 2004 showing chronic ulcerative inflammation with reparatory areas of squamous immature benign metaplasia In April 2014, a dermatological consult described vulvar scleroatrophic lichen confirmed by a biopsy. | 26193225 |
| Inflammation, Atherosclerosis | Altered Intercellular Communication | Pretransplant malnutrition, inflammation, and atherosclerosis affect cardiovascular outcomes after kidney transplantation. | 26194096 |
| Kidney Failure, Chronic, Inflammation, Malnutrition, Atherosclerosis | Altered Intercellular Communication | Malnutrition, inflammation, and atherosclerosis (MIA) syndrome is associated with a high mortality rate in patients with end-stage renal disease. | 26194096 |
| Acute inflammation | Altered Intercellular Communication | Energized dissection adds to the cytokine-mediated postoperative inflammation. | 26194253 |
| prostatitis | Altered Intercellular Communication | Patients With Prostatic Inflammation Undergoing Transurethral Prostatic Resection Have a Larger Early Improvement of Storage Symptoms. | 26194294 |
| Metabolic Syndrome X, ETV3 wt Allele, prostatitis | Altered Intercellular Communication | To evaluate the association between prostate inflammation, metabolic syndrome (MetS), and postoperative lower urinary tract symptoms in patients treated with transurethral resection of the prostate (TURP). | 26194294 |
| prostatitis | Altered Intercellular Communication | Patients with prostate inflammation presented a 50% risk reduction of postoperative storage urinary symptoms. | 26194294 |
| ETV3 wt Allele, prostatitis | Altered Intercellular Communication | We confirmed the association between MetS and prostate inflammation.Patients with inflammatory infiltrates mostly benefit from TURP, particularly regarding storage symptoms. | 26194294 |
| Chronic lymphocytic inflammation, Pontine structure, Clippers | Altered Intercellular Communication | Chronic Lymphocytic Inflammation with Pontine Perivascular Enhancement Responsive to Steroids (CLIPPERS Syndrome) was first described in 2010. | 26195048 |
| Atherosclerosis | Altered Intercellular Communication | IRF2BP2 Reduces Macrophage Inflammation and Susceptibility to Atherosclerosis. | 26195219 |
| Atherosclerosis | Altered Intercellular Communication | Inflammation impairs macrophage cholesterol clearance from vascular tissues and promotes atherosclerosis. | 26195219 |
| Degenerative polyarthritis, Inflammation | Altered Intercellular Communication | Low-grade inflammation in symptomatic knee osteoarthritis: prognostic value of inflammatory plasma lipids and peripheral blood leukocyte biomarkers. | 26195278 |
| Degenerative polyarthritis, Inflammation | Altered Intercellular Communication | These findings may reflect low-grade inflammation in OA and may be useful as diagnostic and prognostic biomarkers in clinical development of disease-modifying OA drugs. | 26195278 |
| Inflammation, Metabolic Syndrome X | Altered Intercellular Communication | Platelet to lymphocyte ratio as a novel indicator of inflammation is correlated with the severity of metabolic syndrome: A single center large-scale study. | 26196312 |
| Inflammation, Blood coagulation | Altered Intercellular Communication | Increased visceral adiposity activates the important pathways connecting low-grade chronic inflammation, oxidative stress and blood coagulation. | 26196312 |
| Inflammation, ETV3 wt Allele | Altered Intercellular Communication | In conclusion, our findings showed that increased PLR was significantly associated with both the presence and severity of MetS which was linked to systemic inflammation based on the correlation between PLR and CRP. | 26196312 |
| Inflammation | Altered Intercellular Communication | The result was consistent with erosive mucosa with granulation tissue formation and acute inflammation in favor of EM. | 26196523 |
| Inflammation, Ulcerative Colitis | Altered Intercellular Communication | However, a systematic analysis of various colonic subcompartments in the pathogenesis of UC before inflammation remains elusive. | 26197452 |
| Inflammation, Ulcerative Colitis | Altered Intercellular Communication | Our results thus provide new insights into the development of inflammation and relapse in UC and suggest that the stem cell niche in the colon may influence pathogenesis of the disease. | 26197452 |
| Inflammation, Physical disability, Sarcopenia | Altered Intercellular Communication | Sarcopenia has been associated with increased systemic inflammation and risk of physical disability in older adults. | 26197717 |
| Inflammation, Fever, Lymphohistiocytosis, Hemophagocytic, Hyperferritinaemia | Altered Intercellular Communication | The diagnosis of HLH should be considered in patients who are systemically ill with unexplained fevers and hyperferritinemia who have evidence of inflammation in the CNS. | 26198020 |
| Data types - Address | Altered Intercellular Communication | Neurosteroids have recently shown promise in alleviating cognitive and neuronal sequelae of AD. | 26198711 |
| Arteritis | Altered Intercellular Communication | Carotid artery inflammation associated with gemcitabine-based therapy: a special report. | 26198835 |
| Inflammation, Vasculitis, CTCAE, Thickened | Altered Intercellular Communication | Vasculitis is an inflammation that can present as acute or chronic in nature, which causes changes in the walls of blood vessels, including thickening, weakening, narrowing and scarring. | 26198835 |
| Pain Distress Question, Inflammation | Altered Intercellular Communication | Despite adequate pain control, thoracotomy was still associated with significant central and peripheral inflammation. | 26198932 |
| Granuloma, Inflammation | Altered Intercellular Communication | CNGM was characterized by lobulocentric granulomas with mixed inflammation and clear vacuoles lined by neutrophils within granulomas. | 26200100 |
| Inflammation, Carcinoma of lung, Tuberculosis, Pulmonary | Altered Intercellular Communication | It may usually be misdiagnosed as inflammation including pulmonary tuberculosis, even lung cancer, because its clinical symptoms and signs are often nonspecific. | 26200643 |
| Inflammation | Altered Intercellular Communication | Inflammation was suspected, but malignance cannot be excluded. | 26200643 |
| Obesity | Altered Intercellular Communication | Obesity Is a Positive Modulator of IL-6R and IL-6 Expression in the Subcutaneous Adipose Tissue: Significance for Metabolic Inflammation. | 26200663 |
| Inflammation | Altered Intercellular Communication | The role of IL-6R/IL-6 axis in metabolic inflammation remains controversial. | 26200663 |
| Inflammation, Obesity | Altered Intercellular Communication | It was, therefore, concluded that obesity was a positive modulator of IL-6R and IL-6 expression in the adipose tissue which might be a contributory mechanism to induce metabolic inflammation. | 26200663 |
| Inflammation, Depression, CTCAE | Altered Intercellular Communication | Relationship Between Physical Frailty and Low-Grade Inflammation in Late-Life Depression. | 26200706 |
| Inflammation, Depression, CTCAE | Altered Intercellular Communication | To determine whether physical frailty is associated with low-grade inflammation in older adults with depression, because late-life depression is associated with physical frailty and low-grade inflammation. | 26200706 |
| Inflammation, Bipolar Disorder | Altered Intercellular Communication | Only performance-based physical frailty is associated with low-grade inflammation in late-life depression, which might point to a specific depressive subtype. | 26200706 |
| Arterial Stiffness, Inflammation, Prediabetes syndrome, Diabetes Mellitus | Altered Intercellular Communication | Arterial stiffness and endothelial inflammation in prediabetes and newly diagnosed diabetes patients. | 26201008 |
| Arterial Stiffness, Inflammation, Prediabetes syndrome, Diabetes Mellitus | Altered Intercellular Communication | We aimed to study e-selectin levels, and their associations with serum markers of inflammation and arterial stiffness in prediabetes and newly diagnosed diabetes patients in this study. | 26201008 |
| Inflammation, physiopathological | Altered Intercellular Communication | Serum e-selectin may be a good marker of endothelial inflammation and dysfunction increasing in parallel with serum glucose levels, predicting future cardiovascular events. | 26201008 |
| ARCN1 gene, Inflammation, Chronic Obstructive Airway Disease, Excessive | Altered Intercellular Communication | COPD (chronic obstructive pulmonary disease) is associated with sustained inflammation, excessive injury, and accelerated lung aging. | 26201096 |
| Inflammation | Altered Intercellular Communication | Moreover, KL depletion increased cell sensitivity to cigarette smoke-induced inflammation and oxidative stress-induced cell damage. | 26201096 |
| ARCN1 gene, Inflammation | Altered Intercellular Communication | Reduced KL expression in COPD airway epithelial cells was associated with increased oxidative stress, inflammation and apoptosis. | 26201096 |
| Inflammation, Chronic sinusitis, Craniosynostosis, Obesity | Altered Intercellular Communication | Both obesity and chronic rhinosinusitis (CRS) are characterized by inflammation. | 26201473 |
| Dermatitis, Atopic, Psoriasis | Altered Intercellular Communication | Expression of Neuropeptides, Neurotrophins, and Neurotransmitters in the Skin of Patients with Atopic Dermatitis and Psoriasis. | 26201903 |
| Gingivitis, Dental Plaque | Altered Intercellular Communication | Secondary end points were levels of dental plaque and gingival inflammation. | 26202995 |
| Bacteremia, Hypotension, CTCAE, Inflammation, Renal Insufficiency | Altered Intercellular Communication | The main clinical predictors of bacteremia were antibiotic use, hypotension, renal dysfunction and systemic inflammation. | 26203565 |
| Blepharitis, Conjunctivitis | Altered Intercellular Communication | Sixteen patients with posterior blepharitis and conjunctival inflammation due to MGD were treated with azithromycin, 1%, drops for 4 weeks. | 26204109 |
| Arthralgia, Inflammation, Pericarditis, CTCAE, Raynaud Phenomenon | Altered Intercellular Communication | A 17-year-old adolescent girl was admitted with chronic arthralgia, Raynaud phenomenon, pericarditis, and evidences of chronic diffuse inflammation. | 26204208 |
| Inflammation, Kidney Failure | Altered Intercellular Communication | Is there a connection between inflammation, telomerase activity and the transcriptional status of telomerase reverse transcriptase in renal failure? | 26204404 |
| Sarcopenia | Altered Intercellular Communication | This process, known as "inflamm-aging," is associated with physical frailty and sarcopenia. | 26204934 |
| Inflammation | Altered Intercellular Communication | Increased inflammation but similar physical composition and function in older-aged, HIV-1 infected subjects. | 26204934 |
| Inflammation, HIV-1 Infection Pathway, Physical impairment | Altered Intercellular Communication | The purpose of our study was to determine if inflammation during treated HIV-1 infection worsens physical impairment in older individuals. | 26204934 |
| Inflammation | Altered Intercellular Communication | Despite careful balancing for age, BMI, medications and co-morbidities, the HIV-infected group still displayed evidence of significant chronic inflammation, including elevated sCD14, CRP, IL-6 and CD57(+) T cells, although the magnitude of this inflammation was unrelated to physical impairment. | 26204934 |
| Inflammation, Injury of kidney | Altered Intercellular Communication | No significant difference was observed in the levels of biomarkers for renal injury and systemic inflammation response. | 26205311 |
| Acute Coronary Syndrome, Electrocardiogram: myocardial infarction (finding), Inflammation | Altered Intercellular Communication | (Comparison of Biomatrix Versus Gazelle in ST-Elevation Myocardial Infarction [STEMI] [COMFORTABLE]; NCT00962416; and Inflammation and Acute Coronary Syndromes [SPUM-ACS]; NCT01000701). | 26205445 |
| Emphysematous cystitis | Altered Intercellular Communication | Emphysematous cystitis is an unusual inflammatory condition characterised by the presence of air within the bladder wall and lumen. | 26206783 |
| Acute Kidney Injury, CTCAE, Inflammation, Traumatic injury, Clostridium difficile enteritis | Altered Intercellular Communication | Analysis of severe blunt trauma patients with C. difficile, as compared with non-CDI patients, reveals evidence of increased inflammation, immunosuppression, worse acute kidney injury, higher NISS, greater days in the hospital and on the ventilator, higher organ injury scores, and prolonged clinical courses. | 26207402 |
| CX3CL1 wt Allele, Inflammation, Traumatic injury, Communicable Diseases | Altered Intercellular Communication | FKN is multifactorial in origin: androgens, inflammation, trauma, ingrowing hairs and secondary infection have all been implicated in its aetiology. | 26207661 |
| Inflammation, Squamous cell carcinoma of esophagus | Altered Intercellular Communication | Diet and inflammation have been suggested to be important risk factors for esophageal squamous cell cancer (ESCC). | 26208592 |
| Inflammation, Cardiovascular Diseases, Refractory anemias, Cyclophosphamide/Vincristine/Dacarbazine Regimen, Rheumatoid Arthritis, Haiti, Hypertension, CTCAE | Altered Intercellular Communication | Both nocturnal hypertension (HT) and systemic inflammation underlying rheumatoid arthritis (RA) have been shown to be independent predictors of cardiovascular disease (CVD), although little is known on the relationship between nocturnal blood pressure (BP) and disease activity in RA patients. | 26208672 |
| Glaucoma, CTCAE, Acute inflammation | Altered Intercellular Communication | Glaucoma cases were more likely to have postoperative inflammation (OR 1.73, P < .0001), prolonged elevated intraocular pressure (OR 2.96, P = .0003), and additional surgery within 30 days (OR 1.92, P = .03). | 26210863 |
| Inflammatory abnormality of the eye | Altered Intercellular Communication | Fourteen patients (56%) presented with ocular surface inflammation. | 26210866 |
| Inflammation | Altered Intercellular Communication | Though typically noninflammatory, a variant form characterized by prominent inflammation exists. | 26210866 |
| Inflammation | Altered Intercellular Communication | When inflammation was intense, covering ileostomy was performed, and an omental plasty was placed between the bowel anastomosis and bladder. | 26211219 |
| Diastolic dysfunction, Inflammation, Renal function, Renal Insufficiency | Altered Intercellular Communication | Our main findings were that (i) HF patients had significantly higher serum DLL1 levels than healthy control subjects, (ii) DLL1 levels were significantly correlated with neurohormonal activation, systemic inflammation, and impaired kidney function, (iii) high DLL1 levels were associated with diastolic dysfunction and reduced exercise capacity, but not with impaired systolic function, and (iv) in univariate analysis, but not after multivariable adjustment, high levels of DDL1 were associated with adverse outcome. | 26211721 |
| Inflammation, Fibrosis Assessment, Injury of liver | Altered Intercellular Communication | Chemokines, such as CXCR3-ligands, have been identified to play an important role during hepatic injury, inflammation and fibrosis. | 26212075 |
| Lichen Planus | Altered Intercellular Communication | Lichen planus (LP) is an autoimmune inflammatory condition of the skin and mucous membranes, of unknown aetiology, that infrequently involves the eye. | 26212185 |
| Synaptic Transmission, Epileptic Syndromes, Syndrome, Intellectual Disability | Altered Intercellular Communication | Syntaxin Binding Protein 1 (STXBP1) mutations determine a central neurotransmission dysfunction through impairment of the synaptic vesicle release, thus causing a spectrum of phenotypes varying from syndromic and non-syndromic epilepsy to intellectual disability of variable degree. | 26212315 |
| Refractory anemias, Degenerative polyarthritis | Altered Intercellular Communication | Mixed synoviocytes in RA and OA possessed all major Gas-coupled neurotransmitter receptors. | 26212359 |
| Inflammation, Heart failure, Bipolar Disorder | Altered Intercellular Communication | NGAL and other markers of inflammation as competitive or complementary markers for depressive symptom dimensions in heart failure. | 26212793 |
| Communicable Diseases | Altered Intercellular Communication | Sixteen T-Ports had been explanted due to 15 stoma reactions (14 inflammations and one infection) and one tilting of the T-Port. | 26213103 |
| Inflammation, Aortic Aneurysm | Altered Intercellular Communication | PPAR-g agonist attenuates inflammation in aortic aneurysm patients. | 26213347 |
| Fibrosis Assessment, Hepatitis | Altered Intercellular Communication | All 3 laboratory indices of fibrosis accurately reflected liver fibrosis in patients with SVR for 5 years despite the normalization of serum liver transaminase activity and the lack of liver inflammation. | 26214180 |
| Inflammation, dystrophic, Fibrosis Assessment, Muscle fiber necrosis, Paresis, Cachexia | Altered Intercellular Communication | The disease phenotype is characterized by muscle weakness and wasting, and dystrophic features including muscle fiber necrosis, inflammation and fibrosis. | 26214262 |
| Inflammation, Malnutrition, Toxic effect, Malignant Head and Neck Neoplasm, Mental disorders | Altered Intercellular Communication | Effect on long-term survival of psychiatric disorder, inflammation, malnutrition, and radiotherapy-related toxicity in patients with locally advanced head and neck cancer. | 26214644 |
| Inflammation, Malnutrition, Toxic effect | Altered Intercellular Communication | Inflammation, malnutrition and RT-related toxicity had no significant impact on OS. | 26214644 |
| Communicable Diseases, Inflammation, Hepatitis C | Altered Intercellular Communication | It is generally accepted that inflammation that occurs in response to hepatocyte infection by the hepatitis C virus (HCV) is the main mechanism that triggers myofibroblast differentiation and stimulation in chronic hepatitis C. The aim of this study was to determine if HCV might infect human liver myofibroblasts (HLMF) and directly stimulate their fibrogenic activities. | 26214688 |
| Liver carcinoma, Hepatitis, Chronic | Altered Intercellular Communication | Chronic liver inflammation and immune/inflammatory response promote hepatocellular carcinoma. | 26215124 |
| Neoplasms | Altered Intercellular Communication | High densities of liver-infiltrating lymphocytes in HCV-HCC cirrhotic parenchyma prevail inflammatory conditions and could contribute to tumorigenesis and tumour recurrence. | 26215124 |
| Intraocular inflammation, Infiltration, Vitreous opacities | Altered Intercellular Communication | In these patients, intraocular inflammation and vitreous opacities resolved, and chorioretinal infiltrates evolved into fibrotic scars. | 26215152 |
| Inflammation | Altered Intercellular Communication | The intervening stroma showed granulation tissue with severe active chronic inflammation. | 26216921 |
| Intestinal metaplasia, Inflammation, Gland | Altered Intercellular Communication | Chronic inflammation, neutrophil activity, glandular atrophy, and intestinal metaplasia scores were significantly lower in Mongolian compared to Japanese H. pylori-positive patients (P < 0.0001), with the exception of the intestinal metaplasia score of specimen from the greater curvature of the upper body. | 26217093 |
| Hashimoto Disease, Inflammation, Endothelial dysfunction, Haiti | Altered Intercellular Communication | The etiopathogenesis of Hashimoto's thyroiditis (HT) - has not been clearly elucidated although the role of chronic inflammation, endothelial dysfunction, and imbalance between pro- and anti-inflammatory cytokines has been established. | 26218277 |
| Inflammation, Blood Vessel | Altered Intercellular Communication | C-reactive protein (CRP) is a biomarker of inflammation, and high levels of CRP correlate with vascular death. | 26218286 |
| Neurodegenerative Disorders, Inflammation, Nerve Degeneration | Altered Intercellular Communication | Chronic inflammation is considered to be involved in neurodegeneration, although there is no evidence linking it with the process of neurodegenerative diseases. | 26218286 |
| palladium, Inflammation | Altered Intercellular Communication | The associations were independent from PD duration, PD severity, cognitive function, ages, and nutritional conditions, suggesting the possibility that subclinical chronic inflammation is associated with a neurodegenerative process in PD. | 26218286 |
| Inflammation, Clostridium perfringens, Necrosis | Altered Intercellular Communication | The microbiology report of blood culture revealed clostridium perfringens, while her pathology showed necrosis and acute inflammation of fibroadipose tissue, skeletal muscle, and fat. | 26218953 |
| Diabetes Mellitus, Non-Insulin-Dependent, Obesity, Cardiovascular Diseases | Altered Intercellular Communication | Adiposity is an inflammatory condition contributing to the morbidity and mortality of several disorders, including type 2 diabetes mellitus (T2D) and cardiovascular disease. | 26219155 |
| Fibrosis Assessment, Calcinosis, Acute and chronic inflammation, Pericarditis, Constrictive | Altered Intercellular Communication | Constrictive pericarditis (CP) is an uncommon disease resulting from chronic pericardial inflammation, fibrosis and calcification. | 26219528 |
| Proctitis, Inflammation, Colorectal Carcinoma | Altered Intercellular Communication | More work is needed to determine whether IL-6 is a valid marker of colorectal inflammation and whether such inflammation contributes to colon and rectal cancer risk. | 26220152 |
| Inflammation | Altered Intercellular Communication | Prognostic value of (18)F-fluorodeoxyglucose PET-CT imaging in acute aortic syndromes: comparison with serological biomarkers of inflammation. | 26220267 |
| Carcinoma of lung | Altered Intercellular Communication | Circulating Inflammation Markers, Risk of Lung Cancer, and Utility for Risk Stratification. | 26220734 |
| Inflammation, Carcinoma of lung | Altered Intercellular Communication | The incorporation of an inflammation score combining these four markers did not improve the sensitivity (77.6% vs 75.8%, P = .33) or specificity (56.1% vs 56.1%, P = .98) of risk-based lung cancer models. | 26220734 |
| ovarian neoplasm, Carcinogenesis, Inflammation, Carcinoma of lung | Altered Intercellular Communication | Circulating levels of CRP, SAA, sTNFRII, and CXCL9/MIG were reproducibly associated with lung cancer risk in two independent studies within the Prostate, Lung, Colorectal, and Ovarian Cancer Screening Trial, underscoring an etiologic role for inflammation in lung carcinogenesis, though replication is needed in other populations. | 26220734 |
| Inflammation, Pneumoconiosis | Altered Intercellular Communication | The interleukin 17A (IL-17A) which is located on chromosome 6p and has been linked to chronic inflammation, is an important candidate gene conferring coal workers' pneumoconiosis (CWP). | 26223249 |
| Inflammation, Malnutrition, Communicable Diseases, malignant disease, Liver damage, Traumatic injury | Altered Intercellular Communication | Its serum level is reduced in many clinical conditions, such as liver damage, inflammation, injury, infection, malnutrition, and malignant disease. | 26223693 |
| Inflammation, Colonization | Altered Intercellular Communication | We hypothesized bacterial colonization promotes inflammation and that might be associated with renal outcome. | 26223871 |
| Inflammation | Altered Intercellular Communication | Also these diseases are associated with chronic inflammation. | 26224042 |
| Inflammation, Acromegaly | Altered Intercellular Communication | Our study results suggest that subclinical inflammation may play a role in increased incidence of mortality and morbidity, which depends on uncontrolled IGF-1 levels in patients with acromegaly. | 26224042 |
| Inflammation, Obesity | Altered Intercellular Communication | Low-grade chronic inflammation is a salient feature of obesity and many associated disorders. | 26224080 |
| Inflammation, Obesity | Altered Intercellular Communication | Understanding how obesity is related to inflammation may allow the development of therapeutics aimed at improving metabolic parameters in obese patients. | 26224080 |
| Inflammation | Altered Intercellular Communication | These novel findings suggest that the deregulated hyper-responsiveness to hypoxic stimulus of ASC from visceral AT of obese subjects may contribute via paracrine mechanisms to low-grade chronic inflammation, which has been implicated in obesity-related morbidity. | 26224080 |
| Inflammation, Cardiovascular Diseases | Altered Intercellular Communication | Low-grade chronic inflammation plays a pathogenic role in cardiovascular disease. | 26224329 |
| Infectious Lung Disorder, Pneumonitis | Altered Intercellular Communication | Exhaled nitric oxide (eNO) and carbon monoxide (eCO) are markers of pulmonary inflammation associated with acute graft rejection and lung infections in lung transplant (LTX) recipients. | 26224473 |
| Airway structure | Altered Intercellular Communication | LTX patients affected by BOS showed higher levels of FeNO 150 and 350, and CalvNO than non-BOS LTX patients, probably due to chronic airway inflammation and fibrotic remodelling. | 26224473 |
| Inflammation, Dental Plaque | Altered Intercellular Communication | These findings suggest that the limited capacity of MSCs to differentiate into macrophages could possibly result in decreased macrophage density within the arterial plaque, reduced inflammation, and subsequently enhance plaque stability. | 26224580 |
| palladium, Inflammation, Malnutrition, diabetic | Altered Intercellular Communication | Baseline 25(OH)D level was 16.15 (12.13 - 21.16) nmol/L, which was closely associated with diabetic status, longer PD duration, malnutrition, and inflammation. | 26224791 |
| Chronic myeloproliferative disorder | Altered Intercellular Communication | Evaluation of Inflammation Parameters in Philadelphia Negative Chronic Myeloproliferative Neoplasia Patients. | 26225646 |
| Inflammation, Chronic myeloproliferative disorder | Altered Intercellular Communication | Recent studies have suggested that chronic inflammation can be a triggering factor in the clonal change in chronic myeloproliferative neoplasia (CMPN). | 26225646 |
| Inflammation | Altered Intercellular Communication | Nepalese patients infected with strains belonging to hpEurope showed higher inflammation in the antrum than strains from the Nepalese specific population (P = 0.05). | 26226153 |
| ARCN1 gene, Airway structure | Altered Intercellular Communication | COPD is characterized by chronic airway inflammation and remodeling, with serious modifications of the extracellular matrix (ECM). | 26226411 |
| Airway structure | Altered Intercellular Communication | AECOPDs are associated with increased HYAL activity in BAL and subsequent degradation of HA, which may contribute to airway inflammation and subsequent lung function decline during exacerbations. | 26226411 |
| Orbital Pseudotumor | Altered Intercellular Communication | Periprosthetic Tissue Loss in Patients With Idiopathic Vitreous Inflammation After the Boston Keratoprosthesis. | 26226472 |
| Inflammation | Altered Intercellular Communication | Blood-cell bioenergetics are associated with physical function and inflammation in overweight/obese older adults. | 26226578 |
| Exanthema, Fever, CTCAE, Interstitial inflammation, Dysplasia of anus, Nephritis, Interstitial, Tubulitis Assessment, Acute Kidney Injury, CTCAE | Altered Intercellular Communication | Acute interstitial nephritis (AIN) presents with acute kidney injury, with evidence of interstitial inflammation and tubulitis on histology, and the presence of fever, rash, and eosinophiluria. | 26226951 |
| Inflammation | Altered Intercellular Communication | Plasma TNF-a Is Associated with Inflammation and Nutrition Status in Community-Dwelling Japanese Elderly. | 26226964 |
| Malnutrition, Disability, Inflammation, Obesity | Altered Intercellular Communication | Inflammation has been suggested to play an important role in age-related chronic diseases and disability, and it is associated with nutritional status including obesity and malnutrition. | 26226964 |
| Inflammation, Malnutrition | Altered Intercellular Communication | The results of this study suggest that plasma TNF-a is associated with inflammation and insulin resistance in both Japanese elderly men and women, and a prominent association of TNF-a with malnutrition status was observed in elderly women. | 26226964 |
| physiopathological | Altered Intercellular Communication | These results suggest that PCDH1 is important for airway function as a physical barrier, and its dysfunction is involved in the pathogenesis of allergic airway inflammation. | 26227965 |
| Intraocular inflammation | Altered Intercellular Communication | Visual acuity improved in 12 eyes (86 %) and intraocular inflammation decreased in 13 eyes (93 %) from 1 week to 3 months after the first injection. | 26228441 |
| Malignant - descriptor, Inflammation | Altered Intercellular Communication | In patients with complete or near eradication of malignant T cells, residual clinical inflammation was associated with cytokine production by benign T cells. | 26228486 |
| Inflammation, Carcinoma of lung | Altered Intercellular Communication | From January 2010 to May 2012, we retrospectively studied 459 metastatic lymph nodes in 298 lung cancer patients and 176 reactive lymph nodes in 90 patients with nonspecific inflammation. | 26228606 |
| Inflammation, Obesity | Altered Intercellular Communication | Educational level and chronic inflammation in the elderly--the role of obesity: results from the population-based CARLA study. | 26230620 |
| Inflammation, Obesity | Altered Intercellular Communication | General obesity mediates roughly one-third of the association of education with chronic inflammation in the elderly. | 26230620 |
| Inflammation, Impaired cognition, Hyponatremia | Altered Intercellular Communication | Fifty patients (10.5%) had hyponatremia; these patients tended to be older and less educated, to have less inflammation, and to have the higher prevalence of cognitive impairment. | 26231192 |
| Inflammation, Interstitial inflammation | Altered Intercellular Communication | The rA2-19F strain in neonatal mice caused substantial lung pathology including interstitial inflammation and airway mucus production, while A2 caused minimal inflammation and mucus production. | 26231396 |
| Pneumonitis | Altered Intercellular Communication | Pulmonary inflammation was characterized by enhanced Th2 and reduced Th1 and effector CD8(+) T cells compared to A2. | 26231396 |
| Presenile dementia, Inflammation, Atherosclerosis | Altered Intercellular Communication | Age-related diseases, such as atherosclerosis and dementia, are associated with oxidative stress and chronic inflammation. | 26231485 |
| Fibrosis Assessment, Pneumonitis | Altered Intercellular Communication | Pleiotropic effect of the proton pump inhibitor esomeprazole leading to suppression of lung inflammation and fibrosis. | 26231702 |
| Pulmonary Emphysema, Pneumonitis | Altered Intercellular Communication | Bilirubin treatment suppresses pulmonary inflammation in a rat model of smoke-induced emphysema. | 26232645 |
| Airway structure, Pulmonary Emphysema | Altered Intercellular Communication | Cigarette smoking is a significant risk factor for emphysema, which is characterized by airway inflammation and oxidative damage. | 26232645 |
| Arthritis, Joints | Altered Intercellular Communication | In RA joints, FDG uptake was seen mostly by inflammatory cells; therefore, FDG uptake reflected joint inflammation. | 26232929 |
| Alzheimers Disease", Impaired cognition | Altered Intercellular Communication | Disruption of cholinergic neurotransmission exacerbates Ab-related cognitive impairment in preclinical Alzheimer's disease. | 26233262 |
| Alzheimers Disease", Data types - Address | Altered Intercellular Communication | Disruption in cholinergic neurotransmission is one of the earliest neuropathological changes in preclinical Alzheimer's disease (AD) and may be associated with abnormal beta-amyloid (Ab) accumulation. | 26233262 |
| Cognition Disorders, Data types - Address | Altered Intercellular Communication | Therefore, disruption of cholinergic neurotransmission with scopolamine may unmask otherwise undetectable cognitive deficits in preclinical AD. | 26233262 |
| Inflammation, Behcet Syndrome | Altered Intercellular Communication | Lower CYP2C9 activity in Turkish patients with Behcet's disease compared to healthy subjects: a down-regulation due to inflammation? | 26233334 |
| Sepsis, Inflammation | Altered Intercellular Communication | These findings tend to support previous reports that indicated that Gas6 behaves as an acute phase reactant and can be considered a general marker of inflammation rather than a specific biomarker of sepsis. | 26233610 |
| Inflammation, Chronic disease, Nerve Degeneration | Altered Intercellular Communication | Multiple sclerosis (MS) is a chronic disease of the central nervous system characterized by inflammation and accompanied and followed by neurodegeneration. | 26233805 |
| Nephritis, Interstitial, Inflammation, Kidney Diseases, Renal glomerular disease | Altered Intercellular Communication | Postoperatively, an elevation of the serum IgG4 level was confirmed at 403 mg/dL; however, there was no evidence of tubulointerstitial nephritis or glomerulopathy, including membranous nephropathy, and the urothelium of the renal pelvis was intact without inflammation. | 26234232 |
| Granulomatosis, Granulomatosis with polyangiitis, Systemic Vasculitis | Altered Intercellular Communication | Granulomatosis with polyangiitis (GPA; formerly Wegener's) can present with clinical and histopathological features similar to those of immunoglobulin-G4 related disease (IgG4-RD), a recently described fibro-inflammatory condition. | 26234733 |
| Airway structure, Asthma, Smooth muscle (tissue), Airway Obstruction | Altered Intercellular Communication | In asthma condition, the airway inflammation accompanied by bronchial smooth muscle spasm cause airway obstruction. | 26234928 |
| Malignant neoplasm of esophagus | Altered Intercellular Communication | Impact of inflammation-based prognostic score on survival after curative thoracoscopic esophagectomy for esophageal cancer. | 26235238 |
| Alzheimers Disease | Altered Intercellular Communication | Nilotinib and bosutinib modulate pre-plaque alterations of blood immune markers and neuro-inflammation in Alzheimer's disease models. | 26235435 |
| Alzheimers Disease", Inflammation, Data types - Address | Altered Intercellular Communication | Alzheimer's disease (AD) brains exhibit plaques and tangles in association with inflammation. | 26235435 |
| Data types - Address | Altered Intercellular Communication | The non-receptor tyrosine kinase Abl is linked to neuro-inflammation in AD. | 26235435 |
| Inflammation | Altered Intercellular Communication | In addition, interleukin-6 (IL-6), albumin, C-reactive protein, and neutrophil gelatinase-associated lipocalin (NGAL) were measured as markers of inflammation. | 26235932 |
| Inflammation, Fibrosis Assessment, Kidney Diseases | Altered Intercellular Communication | In both diseases, the identified peptides were linked to pathways recognized to contribute to nephropathy, including fibrosis, inflammation, angiogenesis, and mineral metabolism. | 26237555 |
| Idiopathic hypertrophic pachymeningitis | Altered Intercellular Communication | Idiopathic hypertrophic pachymeningitis is a rare inflammatory condition with diffuse thickening of the dura mater, which may cause a compressive effect or vascular compromise. | 26238133 |
| Communicable Diseases, Primary malignant neoplasm, Inflammation | Altered Intercellular Communication | NLR gene polymorphisms may shift the balance between pro- and anti-inflammatory cytokines and modulate the risk of infection, chronic inflammation, and cancer. | 26238283 |
| Inflammation, Obesity, Cerebrovascular accident | Altered Intercellular Communication | Epigenetic mechanisms could be involved in obesity, inflammation and stroke. | 26238466 |
| Inflammation, Urinary tract infection, Pain Distress Question | Altered Intercellular Communication | The same enzymes contributing to the synthesis of leukotrienes LTB4 and LTC4, mediators of inflammation and pain, were found in the UTI and ASB cohorts. | 26238715 |
| Inflammation, Lung diseases, Bacterial Infections | Altered Intercellular Communication | Chronic inflammation of the airways is a central component in lung diseases and is frequently associated with bacterial infections. | 26239109 |
| Pneumonitis | Altered Intercellular Communication | In vivo imaging indicated that VR1 strain, releasing in its culture supernatant metalloproteases and other virulence factors, induced lung inflammation while the VR2 strain presented with a severely reduced pro-inflammatory activity. | 26239109 |
| Pain Distress Question, Inflammation | Altered Intercellular Communication | Two-thirds of the patients reported either no pain or only mild intensity pain and moderate inflammation, two days after surgery. | 26241450 |
| Inflammation, Hyperemia | Altered Intercellular Communication | The postoperative conjunctival hyperemia, eye irritation signs and inflammation reactions were mild. | 26241526 |
| Inflammation, Tumor Cell Invasion | Altered Intercellular Communication | It allows the evaluation of periosteal invasion and therefore bone invasion to be reliably distinguished from inflammation or compression. | 26241670 |
| Inflammation, Colorectal Carcinoma | Altered Intercellular Communication | Elevated inflammatory parameters and inflammation scores are associated with poor prognosis in patients undergoing pulmonary metastasectomy for colorectal cancer. | 26242317 |
| Carcinoma, Transitional Cell | Altered Intercellular Communication | The Prognostic Significance of Inflammation-Associated Blood Cell Markers in Patients with Upper Tract Urothelial Carcinoma. | 26242371 |
| Electrocardiogram: myocardial infarction (finding), allergic inflammation | Altered Intercellular Communication | Allergic Inflammation Is Associated With Coronary Instability and a Worse Clinical Outcome After Acute Myocardial Infarction. | 26243785 |
| Acute Coronary Syndrome, allergic inflammation, GDC AJCC Clinical Stage Terminology | Altered Intercellular Communication | The role of allergic inflammation in acute coronary syndromes (ACS) has not been clearly defined to date. | 26243785 |
| Inflammation, Immune dysregulation, Rosacea | Altered Intercellular Communication | Although its etiology is not well defined, rosacea is associated with immune dysregulation and inflammation potentiated by external factors. | 26244354 |
| Retinal Edema, Retinitis, Inflammatory abnormality of the eye | Altered Intercellular Communication | The interaction of photoreceptors with the aging RPE, as well as possible low-grade ocular inflammation causing diffuse inner retinal edema, may be the key to the progressive vision changes in HIV-positive patients without overt retinitis. | 26244973 |
| Inflammation, Fibrosis Assessment | Altered Intercellular Communication | Intestinal fibrosis is a process driven by chronic inflammation leading to increased presence of myofibroblasts and collagen deposition. | 26245217 |
| Inflammation | Altered Intercellular Communication | Severity of inflammation was scored according to the Geboes score on haematoxylin and eosin stainings. | 26245217 |
| Inflammation | Altered Intercellular Communication | Colectomy specimens from patients with acute UC showed significantly more inflammation than those with longstanding disease [19 vs 9 points, p = 0.01]. | 26245217 |
| Inflammation, Edema, Nodularity | Altered Intercellular Communication | She underwent flexible sigmoidoscopy, which demonstrated "patchy inflammation and an isolated area of severe deep ulceration with nodularity and oedema". | 26245287 |
| Nephritis | Altered Intercellular Communication | Deletion of angiotensin-converting enzyme 2 exacerbates renal inflammation and injury in apolipoprotein E-deficient mice through modulation of the nephrin and TNF-alpha-TNFRSF1A signaling. | 26245758 |
| Abnormal renal function, Nephritis, Injury of kidney | Altered Intercellular Communication | More importantly, rhACE2 treatment significantly reversed Ang II-induced renal inflammation, superoxide generation, kidney dysfunction and adverse renal injury in ApoEKO mice with suppression of the NOX4 and TNF-alpha-TNFRSF1A signaling. | 26245758 |
| Nephritis, Injury of kidney | Altered Intercellular Communication | ACE2 deficiency exacerbates kidney inflammation, oxidative stress and adverse renal injury in the ApoE-mutant mice through modulation of the nephrin, NOX4 and TNF-alpha-TNFRSF1A signaling. | 26245758 |
| Renal Insufficiency, Inflammation, Kidney Glomerulus | Altered Intercellular Communication | While rhACE2 supplementation alleviates inflammation, renal dysfunction and glomerulus injury in the ApoE-mutant mice associated with upregulations of Ang-(1-7) levels and nephrin expression and suppression of the TNF-alpha-TNFRSF1A signaling. | 26245758 |
| Tumor necrosis, Progranulins, Inflammation | Altered Intercellular Communication | Progranulin is a growth factor that is active in wound repair and is an antagonist of tumor necrosis factor (TNF) receptors, regulating fibroblast activation, angiogenesis, and inflammation. | 26245842 |
| Inflammation, Pathology | Altered Intercellular Communication | Taken together, our results underscore the importance of NEIL2 in protecting mammals from the development of various pathologies that are linked to genomic instability and/or inflammation. | 26245904 |
| Kidney Failure, Chronic, Inflammation, Atherosclerosis, Diabetes Mellitus, Hypertension, CTCAE | Altered Intercellular Communication | Aside from traditional factors (e.g., diabetes, age, and hypertension), some hematological parameters, such as neutrophil-to-lymphocyte ratio (NLR), red blood cell distribution width (RDW), and mean platelet volume (MPV), have increasingly been reported as measures of systemic inflammation and atherosclerosis in patients with end-stage renal disease (ESRD). | 26246038 |
| Communicable Diseases, Inflammation | Altered Intercellular Communication | Recent research has revealed that although elderly subjects have increased baseline inflammation as compared with their younger counterparts, the elderly do not respond to severe infection or injury with an exaggerated inflammatory response. | 26246141 |
| Refractory anemias, Rheumatoid Arthritis, Inflammation, atherosclerotic | Altered Intercellular Communication | Results of a recent study suggested that the excess cardiovascular (CV) risk observed in patients with rheumatoid arthritis (RA) could be partially explained by the presence of immune complexes of antibodies against citrullinated proteins that locally promote and perpetuate inflammation and progression of atherosclerotic plaques. | 26246227 |
| Inflammation, Obesity | Altered Intercellular Communication | A secondary aim is to determine whether these relationships are mediated by a reduction in underlying subclinical inflammation associated with obesity. | 26246241 |
| Inflammation, Atrophy of cerebellum | Altered Intercellular Communication | Cerebrospinal fluid showed continuous inflammation and magnetic resonance imaging (MRI) revealed cerebellar atrophy and hot cross-bun sign. | 26248690 |
| Fibrosis Assessment, Pneumonitis | Altered Intercellular Communication | Our findings suggest that increased Gal-9 levels in the lung have a protective role against lung inflammation and fibrosis in patients with COP through the induction of Tregs in the lung and CD44-dependent inhibitory effects on lung fibroblast cells. | 26249221 |
| Hereditary Diseases, Inflammation, Disease | Altered Intercellular Communication | The clinical diseasome is a network representation of the relationships between diseases, in which diseases are connected if they co-occur more than expected at random; in the molecular diseasome, diseases are linked if they share associated genes or interaction between proteins.The results showed that about half of the disease pairs identified in the clinical diseasome had a biological counterpart in the molecular diseasome, particularly those related to inflammation and vascular tone regulation. | 26250499 |
| Acute inflammation | Altered Intercellular Communication | The agreement between unenhanced MRE vs. CE-MRE in interpreting active bowel inflammation was 96% (123/128 bowel segments; one-sided 95% confidence interval [CI], >94.4%). | 26250897 |
| Inflammation, Traumatic injury | Altered Intercellular Communication | Periodontal inflammation is characterized by injuries in collagen, epithelial, bone tissues. | 26251029 |
| Inflammation | Altered Intercellular Communication | Acute 98.2%, and chronic 89.28% inflammation was a significant positive for myeloperoxidase. | 26251029 |
| Inflammation | Altered Intercellular Communication | The results indicate that the pathogenesis of periodontal inflammation might involve inhibition of cell death, through the overexpression of bcl-2, due to identifying factors myeloperoxidase (result in the DNA damage by the product of catalysis). | 26251029 |
| Inflammation | Altered Intercellular Communication | The highest levels of s100 activity have been found at sites with chronic inflammation. | 26251029 |
| Inflammation, Liver carcinoma, Neoplasms, FAM126A gene | Altered Intercellular Communication | While the roles of HMGB1 in inflammation and cell differentiation have been previously reported, its role in tumor cell migration and invasion, particularly in hepatocellular carcinoma (HCC), has remained elusive. | 26252226 |
| Chronic lymphocytic inflammation, Pontine structure, Clippers, Inflammatory disorder | Altered Intercellular Communication | Chronic lymphocytic inflammation with pontine perivascular enhancement responsive to steroids (CLIPPERS) is an inflammatory disorder of the central nervous system; it has only recently been defined and to date has received only limited attention. | 26252983 |
| Granulomatous inflammation | Altered Intercellular Communication | He will remain under our care to ensure that any further complications such as granulomatous inflammation are managed and documented. | 26252991 |
| Inflammation | Altered Intercellular Communication | For now we can only speculate as to the long-term consequences, but these may include carcinogenic change or granulomatous inflammation. | 26252991 |
| Inflammation, Dyslipidemias, Cerebrovascular accident | Altered Intercellular Communication | Apoptotic markers and DNA damage are related to late phase of stroke: Involvement of dyslipidemia and inflammation. | 26253215 |
| Inflammation, Brain Injuries, Acute Cerebrovascular Accidents | Altered Intercellular Communication | Oxidative stress and brain inflammation are thought to contribute to the pathophysiology of cerebral injury in acute stroke, leading to apoptosis and cell death. | 26253215 |
| Inflammation, Acute Cerebrovascular Accidents | Altered Intercellular Communication | Lipid accumulation may lead to progression of carotid plaques and inflammation, contributing to increased acute stroke risk. | 26253215 |
| Dermatitis, Atopic, Data types - Address, Immune-mediated | Altered Intercellular Communication | Atopic dermatitis (AD) is characterized by epidermal barrier failure and immune-mediated inflammation. | 26253344 |
| Inflammation, Eating | Altered Intercellular Communication | EAT is suggested to promote CAD by paracrine mechanisms and local inflammation. | 26253562 |
| Inflammation, Damage, Cerebrovascular accident | Altered Intercellular Communication | IL-10 expression limits inflammation and restricts the size of CNS damage from stroke. | 26253723 |
| Inflammation | Altered Intercellular Communication | Angiopoietin-like protein-2 (ANGPTL2) mediates chronic inflammation. | 26254352 |
| Primary malignant neoplasm | Altered Intercellular Communication | The Glasgow Prognostic Score (GPS), an inflammation-based prognostic score, has been shown to predict the clinical outcomes of a variety of cancer types. | 26254380 |
| Unresectable Colorectal Carcinoma, Neoplasms | Altered Intercellular Communication | Significance of Markers of Systemic Inflammation for Predicting Survival and Chemotherapeutic Outcomes and Monitoring Tumor Progression in Patients with Unresectable Metastatic Colorectal Cancer. | 26254405 |
| Inflammation, Malignant Neoplasms | Altered Intercellular Communication | Markers of systemic inflammation, such as the neutrophil to lymphocyte ratio (NLR), C-reactive protein (CRP) level and Glasgow prognostic score (GPS), have been reported to be useful prognostic indicators for various types of cancers. | 26254405 |
| Inflammation, Colorectal Carcinoma | Altered Intercellular Communication | However, most of the existing reports investigated the preoperative status, and the significance of markers of systemic inflammation remains unclear in patients with unresectable metastatic colorectal cancer. | 26254405 |
| Inflammation, Colorectal Carcinoma | Altered Intercellular Communication | Pre-treatment markers of systemic inflammation are useful for predicting prognosis in patients with unresectable metastatic colorectal cancer who receive palliative chemotherapy. | 26254405 |
| Diabetic Nephropathy, Inflammation | Altered Intercellular Communication | Recent research has implicated that the inflammation may be a key pathophysiological mechanism in diabetic nephropathy (DN). | 26255081 |
| Inflammation, Dengue Fever | Altered Intercellular Communication | These results suggest that inflammation and endothelial activation are important pathways in the pathogenesis of dengue and sICAM-1 levels may identify individuals at risk of plasma leakage. | 26255888 |
| maltoheptaose binding, Inflammation | Altered Intercellular Communication | S-maltoheptaose targets syndecan-bound effectors to reduce smoking-related neutrophilic inflammation. | 26256047 |
| Airway structure | Altered Intercellular Communication | The antagonistic actions of SM against syndecan-1 binding of NE and CINC-1 in smoke-exposed airways suggest new therapeutic opportunities for modulating airway inflammation in smokers with SM delivery. | 26256047 |
| Senile Plaques, Inflammation | Altered Intercellular Communication | The inclusion criteria were: penile plaque volume <1 cm(3); clinical characteristics and ultrasonographic appearance compatible with active inflammation; and penile curvature <45deg. | 26257044 |
| Inflammation | Altered Intercellular Communication | Several protein plasma levels and protein isotypes related to inflammation and thrombo-coagulating phenomena were independently associated with the risk of future CVD death. | 26258425 |
| Inflammation | Altered Intercellular Communication | Microbial translocation and chronic inflammation may contribute to non-AIDS morbidity in patients with HIV. | 26258571 |
| Inflammation, Observation Method - Coagulation | Altered Intercellular Communication | Probiotic intervention seemed to reduce markers of coagulation and inflammation without overt changes in microbial translocation. | 26258571 |
| Inflammation, Lymphoplasmacytic Infiltrate | Altered Intercellular Communication | Definite histopathological findings and immunohistochemistry revealed profound chronic inflammation, showing lymphoplasmacytic IgG-positive infiltration of a resected part of a common bile duct, highly suggestive for the diagnosis of IAC. | 26259410 |
| Inflammation, Malignant Pleural Mesothelioma, 1-methyl-1-piperidinomethane sulfonate | Altered Intercellular Communication | Chronic inflammation plays a key role in the pathogenesis of malignant pleural mesothelioma (MPM) as a result of asbestos exposure. | 26259877 |
| Airway structure, Carcinoma of lung | Altered Intercellular Communication | Lung cancer may be associated with airway acidification due to enhanced airway inflammation and oxidative stress. | 26260979 |
| Nephritis | Altered Intercellular Communication | And investigations into mechanisms underlying renal inflammation may provide new insight into novel therapeutic targets for patients with DN. | 26261550 |
| Inflammation, Squamous cell carcinoma | Altered Intercellular Communication | Granulomatous inflammation of pulmonary squamous cell carcinoma: a rare phenomenon. | 26261667 |
| Inflammation, Neoplasms | Altered Intercellular Communication | In other instances, granulomatous inflammation is observed in the lymph nodes draining a tumor. | 26261667 |
| Granulomatous inflammation, Squamous cell carcinoma | Altered Intercellular Communication | Herein, we report of a 75-year-old man with pulmonary squamous cell carcinoma (SCC), where granulomatous inflammation was observed extensively at the primary site. | 26261667 |
| Airway structure, neutrophilic, Chronic Obstructive Airway Disease | Altered Intercellular Communication | Chronic Obstructive Pulmonary Disease exacerbations are associated with worsening of airway inflammation, the nature of which may be neutrophilic, eosinophilic, or both. | 26263037 |
| Airway structure, Exacerbation | Altered Intercellular Communication | The primary objective was to examine the cellular nature of airway inflammation in successive COPD exacerbations in order to ascertain if they changed in individual patients. | 26263037 |
| Inflammation | Altered Intercellular Communication | These results indicate that folate and Cbl concentrations may influence the levels of oxidative damage, inflammation, and NAD(H), both systemically and within the CNS. | 26263423 |
| Inflammation | Altered Intercellular Communication | Sustained concentrations of inflammation in young women, not their response to stress, may contribute to their adverse outcomes post-MI. | 26263552 |
| Inflammation | Altered Intercellular Communication | However, environmental factors, such as chronic comorbidities and chronic inflammation, are at least in part responsible for the association between factor VIII and mortality. | 26264493 |
| Ischemia, Inflammation, Cardiac dysfunction | Altered Intercellular Communication | Oxidative stress following ischaemia and reperfusion, as well as inflammation, are thought to be important for the development of cardiac dysfunction after cardiac surgery. | 26265068 |
| Inflammation, Primary malignant neoplasm | Altered Intercellular Communication | Chronic inflammation plays a key role in cancer etiology. | 26265203 |
| Inflammation | Altered Intercellular Communication | The results suggest that aluminum-induced CRP may in part contribute to a pathophysiological state associated with a chronic systemic inflammation of the human vasculature. | 26265215 |
| Inflammation, senile, Data types - Address, "Alzheimers Disease | Altered Intercellular Communication | It is assumed that IL-4 may involve in the inflammation pathology of surrounding senile plaques in Alzheimer's disease (AD) patients. | 26265379 |
| Inflammation, Perforation (observation) | Altered Intercellular Communication | Barium esophagram and esophagogastroduodenoscopy revealed no signs of perforation or inflammation. | 26266352 |
| Inflammation, Fibrosis Assessment, IgG4-Related Sclerosing Disease | Altered Intercellular Communication | IgG4-related disease (IgG4-RD) is a rare entity consisting of inflammation and fibrosis that has been described in multiple organs. | 26266361 |
| Pneumonitis, Alveolar wall | Altered Intercellular Communication | Interestingly, prophylactic BAFFR-Fc administration significantly attenuated pulmonary inflammation and destruction of alveolar walls. | 26266827 |
| Alveolar, Pneumonitis | Altered Intercellular Communication | Antagonizing BAFF in CS-exposed mice attenuates pulmonary inflammation and alveolar destruction. | 26266827 |
| Inflammation, Prostate Cancer Outcomes Study, Polycystic Ovary Syndrome | Altered Intercellular Communication | Selenium supplementation could be effective on reproductive outcomes, biomarkers of inflammation, and oxidative stress among women with polycystic ovary syndrome (PCOS). | 26267328 |
| Inflammation, Metabolic Syndrome X, Atherosclerosis, Cardiovascular Diseases, Sarcopenia, MS gene | Altered Intercellular Communication | evidences have shown a strongly association between metabolic syndrome (MS), cardiovascular diseases and chronic low-grade inflammation, being this last, related with the occurrence of sarcopenia and atherosclerosis. | 26268113 |
| SLC25A20 gene, Pulmonary Emphysema, HIV Infections, Chronic inflammatory disorder | Altered Intercellular Communication | In this cross-sectional study of HIV-infected patients, there was an independent association between emphysema and CAC, after adjustment for traditional cardiovascular risk factors, suggesting a common pathogenesis of these chronic inflammatory conditions in a chronic inflammatory disease such as HIV infection. | 26268373 |
| physiopathological | Altered Intercellular Communication | Active nasal and paranasal sinus inflammation in GPA leads to olfactory dysfunction, the patients are often unaware of. | 26269029 |
| Arteriosclerosis, Interstitial inflammation, Edema, Interstitial Fibrosis Assessment, Tubular atrophy | Altered Intercellular Communication | Scoring was done from 0-3 for interstitial edema, interstitial fibrosis and tubular atrophy (IFTA), interstitial inflammation and arteriosclerosis. | 26269223 |
| Malignant tumor of colon, Inflammation | Altered Intercellular Communication | Analysis of local chronic inflammatory cell infiltrate combined with systemic inflammation improves prognostication in stage II colon cancer independent of standard clinicopathologic criteria. | 26270488 |
| Inflammation, 2000, Stage II Colon Cancer AJCC v7 | Altered Intercellular Communication | In order to evaluate the potential clinical utility of inflammatory markers in Stage II colon cancer, we examined local and systemic inflammation in a consecutive series of patients with resected Stage II colon cancer between 2000 and 2010 who were identified from a prospective clinical database. | 26270488 |
| Inflammation, Chronic pain | Altered Intercellular Communication | By using peripheral inflammation in rats as a chronic pain model, the authors identified the deregulation of proteases and their inhibitors as a hallmark of chronic pain development using a genome-wide screening approach. | 26270939 |
| Inflammation | Altered Intercellular Communication | Endothelial activation and inflammation have been suggested to play an important role in the pathogenesis of cSVD. | 26271106 |
| Esophageal Stricture, Inflammation, Esophagitis | Altered Intercellular Communication | Peptic esophageal strictures due to chronic reflux-associated inflammation were revealed in 0.2% of examined patients (3.7% of patients with erosive esophagitis). | 26271421 |
| Inflammation | Altered Intercellular Communication | Sternoclavicular joint resection was performed usually in 2-3 months after subsidence of inflammation. | 26271565 |
| Cancer-related fatigue, Inflammation, Chronic Kidney Diseases | Altered Intercellular Communication | Inflammation and oxidative stress are involved in the process of chronic renal failure (CRF). | 26271951 |
| Cancer-related fatigue, Inflammation, Sleep disturbances | Altered Intercellular Communication | CRF patients show indication of sleep disturbances, and the melatonin rhythm, which modulates sleep, is abnormal in these patients; however, it is still unclear whether inflammation could be related to the blockage of melatonin production and sleep disturbances in this population. | 26271951 |
| Inflammation, Ventricular arrhythmia, Cardiomyopathies | Altered Intercellular Communication | Incidence of abnormal positron emission tomography in patients with unexplained cardiomyopathy and ventricular arrhythmias: The potential role of occult inflammation in arrhythmogenesis. | 26272522 |
| Ventricular arrhythmia, Myocarditis, Cardiomyopathies | Altered Intercellular Communication | The incidence of myocardial inflammation in patients with unexplained cardiomyopathy referred for ventricular arrhythmias (VAs) is unknown. | 26272522 |
| Inflammation, Sarcoidosis | Altered Intercellular Communication | When biopsy was performed, histologic diagnosis revealed nongranulomatous inflammation in 6 patients and sarcoidosis in 18 patients. | 26272522 |
| Myocarditis, Cardiomyopathies | Altered Intercellular Communication | Nearly 50% of patients referred with unexplained cardiomyopathy and VA demonstrate ongoing focal myocardial inflammation on FDG PET. | 26272522 |
| Inflammation, Chronic Fatigue Syndrome | Altered Intercellular Communication | Comparison of Q fever fatigue syndrome (QFS) and chronic fatigue syndrome (CFS) patients, with a focus on markers of inflammation and fatigue-related cognitive-behavioural variables. | 26272528 |
| Inflammation | Altered Intercellular Communication | Japanese adults (n = 245) aged 80 years were classified into quartiles based on periodontal inflamed surface area (PISA), which quantifies the degree of periodontal inflammation. | 26272677 |
| Parkinson Disease, Inflammation | Altered Intercellular Communication | Amyloid fibrils are the molecular trigger of inflammation in Parkinson's disease. | 26272943 |
| palladium, Inflammation | Altered Intercellular Communication | Although the presence of amyloid deposits of a-synuclein (a-syn) is the main pathological feature, PD brains also present a severe permanent inflammation, which largely contributes to neuropathology. | 26272943 |
| Inflammation, Fibrosis Assessment, Calcinosis | Altered Intercellular Communication | Studies suggest that the progression of CAVS is actively regulated with valve endothelial injury leading to inflammation, fibrosis and calcification. | 26273067 |
| Inflammation, Damage | Altered Intercellular Communication | Such metabolic damage signals may activate inflammasome and trigger chronic inflammation. | 26273672 |
| Diabetic Retinopathy, Acute inflammation | Altered Intercellular Communication | Short Pulse Duration High-Power Laser Photocoagulation during Vitrectomy for Diabetic Retinopathy Reduces Postoperative Inflammation. | 26273824 |
| Inflammation, GDC Disease Response Terminology | Altered Intercellular Communication | The significant lower inflammation after short pulse duration PC than conventional PC indicates that the short pulse duration PC protocol should be considered to treat DR. | 26273824 |
| vascular inflammations, Abnormally opaque structure (morphologic abnormality) | Altered Intercellular Communication | The imaging and intraoperative observations suggest that the opacities behaved like infiltrates and were associated with vitreous rather than vascular inflammation. | 26273931 |
| Refractory anemias, Inflammation | Altered Intercellular Communication | These findings persisted despite adjustment for markers of inflammation (C-reactive protein and interleukin-6 levels) and were seen only in RA, not in controls (adjusted multiplicative interaction P = 0.001-0.077). | 26274015 |
| vascular inflammations | Altered Intercellular Communication | There were no statistically significant differences between the effects of K-MBSR, walking, and patient education on stress, glycemic control, or vascular inflammation. | 26275164 |
| Vascular System Injuries, Inflammation, Pancreatitis Necrotizing | Altered Intercellular Communication | However, this technique must be performed very cautiously due to the risk of vascular injury which can be difficult to repair in the context of severe local inflammation related to pancreatic necrosis. | 26275532 |
| Neuromuscular hamartoma | Altered Intercellular Communication | Neuromuscular and Vascular Hamartoma of the Small Intestine: An Exuberant Reparative Process Secondary to Chronic Inflammation. | 26275621 |
| Inflammation | Altered Intercellular Communication | Our findings, together with current observations in the field, provide a rationale to identify adipocyte-lymphocyte cross-talk that instigates adipose inflammation. | 26276010 |
| Inflammation, Psoriasis | Altered Intercellular Communication | S100A7 (psoriasin) is overexpressed in psoriasis, suggesting a determinant role of this protein in inflammation and keratinocyte differentiation. | 26276441 |
| Inflammation, Cholangiocarcinoma | Altered Intercellular Communication | Association between variants in inflammation and cancer-associated genes and risk and survival of cholangiocarcinoma. | 26276523 |
| Inflammation, Carcinogenesis, FBN2 wt Allele | Altered Intercellular Communication | This study shows a lack of association between variants of genes related to inflammation and carcinogenesis and CCA risk and survival. | 26276523 |
| Inflammation, GDC AJCC Clinical Stage Terminology | Altered Intercellular Communication | The correlation between CRP and UA in the patients with ACS indicates the association of oxidative stress and inflammation intensity in damaged cardiomyocytes. | 26276649 |
| Inflammation, Cardiovascular Diseases | Altered Intercellular Communication | Correlation between UA and CRP in apparently healthy individuals indicates a possible role of UA as a marker of low-grade inflammation and its potential in risk assessment in cardiovascular diseases. | 26276649 |
| Inflammation, Abnormal degeneration | Altered Intercellular Communication | Joint degeneration is considered to result from the direct effects of blood components on cartilage and indirectly from synovial inflammation. | 26276670 |
| Inflammation, Empyema, Tuberculosis | Altered Intercellular Communication | Histopathology revealed 79 (37.6%) cases were tuberculosis, 64 (30.5%) were malignant (primary from lung and other sites), 62 (29.5%) were non-specific inflammation and 5 (2.4%) were empyema. | 26277666 |
| Inflammation, Malignant Neoplasms | Altered Intercellular Communication | Inflammation is an important hallmark of all cancers. | 26277868 |
| Inflammation | Altered Intercellular Communication | Inflammation and increased erythropoiesis stimulating agents (ESA) requirement are frequently associated in patients on dialysis. | 26278270 |
| Inflammation | Altered Intercellular Communication | The observed reduction in ESAdose requirement is independent either on convection or diffusion, but is directly associated to the concomitant reduction of inflammation. | 26278270 |
| Inflammation, Data types - Address | Altered Intercellular Communication | It is accepted that inflammation contributes to the pathogenesis of AD. | 26278415 |
| Granulomatous inflammation, Pneumonia, Interstitial | Altered Intercellular Communication | Significance of granulomatous inflammation in usual interstitial pneumonia. | 26278696 |
| Inflammation | Altered Intercellular Communication | Recently mesenchymal stem cells derived from periodontal ligament (PDLSCs) have been utilized to reconstruct tissues destroyed by chronic inflammation. | 26278788 |
| Inflammation, Endothelial dysfunction, Cerebrovascular accident | Altered Intercellular Communication | We measured biomarkers of inflammation, endothelial dysfunction and hemostasis for >1 month after stroke and compared biomarker levels between stroke subtypes. | 26279056 |
| Inflammation, Thrombosis | Altered Intercellular Communication | These results indicate that, in terms of AMI pathophysiology, the sCD40L cannot be consider just as being involved in thrombosis and inflammation but also as having a relevant role in vascular and endothelial dysfunction. | 26279254 |
| Inflammation, Rheumatoid Arthritis, Cardiovascular Diseases | Altered Intercellular Communication | Antibodies to high-density lipoproteins are associated with inflammation and cardiovascular disease in rheumatoid arthritis patients. | 26279255 |
| Refractory anemias, Inflammation, Rheumatoid Arthritis | Altered Intercellular Communication | Several lines of evidence suggest that chronic inflammation and immune dysregulation are related to altered lipid profiles in rheumatoid arthritis (RA), but the actual mechanisms are still unclear. | 26279255 |
| Inflammation | Altered Intercellular Communication | We determined that aging and amyloid pathology are associated with inflammation and impaired synaptic function in the hippocampal CA1 region as the result of epigenetic-dependent alterations in gene expression. | 26280576 |
| Inflammation | Altered Intercellular Communication | In both amyloid and aging models, inflammation was associated with increased gene expression linked to a subset of transcription factors, while plasticity gene deregulation was differentially mediated. | 26280576 |
| Heart Diseases, Inflammation, Bothered by Vomiting, Headache | Altered Intercellular Communication | This is a case of a 10-year-old girl suffering from cyanotic heart disease that was presented with subacute onset of headache, vomiting, and some signs of inflammation. | 26280627 |
| Communicable Diseases, Inflammation, Intraventricular, Neoplasms | Altered Intercellular Communication | Neuroradiologists suspected an intraventricular tumor, but cardiac history and signs of inflammation led to lumbar puncture and evidence of CNS infection, and intraventricular abscess was suspected. | 26280627 |
| Diabetic Nephropathy, Inflammation | Altered Intercellular Communication | The findings confirm the concept that chronic inflammation is involved in the development of diabetic kidney disease. | 26281195 |
| Inflammation, Uveitis | Altered Intercellular Communication | The primary anatomical location of inflammation is either in the anterior segment or pan uveitis. | 26281489 |
| Sepsis | Altered Intercellular Communication | Analysis of whether patients with primary, secondary and tertiary sepsis, defined by the presence or absence of recent systemic inflammation-inducing events before the onset of sepsis, differ in clinical presentation, microbiological test results, treatment received and outcome. | 26282255 |
| Inflammation, Primary malignant neoplasm | Altered Intercellular Communication | Inflammation plays a crucial role in different stages of cancer development and has long been associated with various types of cancer. | 26282902 |
| Malignant neoplasm of urinary bladder, Cystitis | Altered Intercellular Communication | For this study, 3 groups of subjects were considered: patients harboring bladder cancer, subjects affected by bladder inflammation (CTR1), and healthy subjects (CTR0). | 26282902 |
| Inflammation, Behavior Disorders, Obesity, Diabetes Mellitus | Altered Intercellular Communication | The promotion of adipose tissue inflammation by lifestyle-related diseases such as obesity and diabetes accelerates atherogenesis; however, the underlying mechanisms remain incompletely understood. | 26282945 |
| Inflammation | Altered Intercellular Communication | Nucleotide-binding domain, leucine-rich-containing family, pyrin domain-containing-3 (NLRP3) inflammasome contributes to chronic inflammation in adipose tissue. | 26282945 |
| Inflammation, Infection, Cardiovascular Diseases, Atherosclerosis | Altered Intercellular Communication | Periodontal infections have been linked to cardiovascular disease, including atherosclerosis, and systemic inflammation has been proposed as a possible mediator. | 26282947 |
| Inflammation, Diverticulitis | Altered Intercellular Communication | The groups were equivalent for sex, age, status of diverticulitis, the presence of acute inflammation in the specimen, and the percentage of teaching operations, but the percentage of patients with accompanying diseases was significantly more frequent in groups 2, 3, and 4 (p = 0.04, 0.008, and 0.018, respectively). | 26283162 |
| Inflammation, Nerve Degeneration | Altered Intercellular Communication | Microglia are involved in immune surveillance in intact brains and become activated in response to inflammation and neurodegeneration. | 26283879 |
| Inflammation | Altered Intercellular Communication | The source of this chronic inflammation is due to the repeated and progressive activation of immune cells. | 26284585 |
| ARCN1 gene, Pneumonitis | Altered Intercellular Communication | Our results indicate that age-induced lung inflammation is further elevated after CS exposure in old mice, potentially via an age-induced change in immune cell susceptibility to CS thereby accelerating the pathophysiological hallmarks of COPD. | 26284585 |
| prostatitis | Altered Intercellular Communication | Transition Zone Prostate-specific Antigen Density Could Better Guide the Rebiopsy Strategy in Men With Prostate Inflammation at Initial Biopsy. | 26284593 |
| prostatitis | Altered Intercellular Communication | To assess the role of transition zone prostate-specific antigen density (TZPSAD) in determining rebiopsy strategy in men with prostate inflammation at initial biopsy. | 26284593 |
| Inflammation, Prostate | Altered Intercellular Communication | Eligible patients were divided into 2 groups based on the presence of chronic inflammation in prostate. | 26284593 |
| Inflammation | Altered Intercellular Communication | Group 1 consisted of 920 patients with histopathologic evidence of chronic inflammation and group 2 consisted of 1287 patients with no evidence of inflammation. | 26284593 |
| Inflammation, Primary malignant neoplasm | Altered Intercellular Communication | Chronic inflammation at initial biopsy was associated with a significant decrease in the likelihood of cancer detection during rebiopsy (odds ratio, 0.42; 95% confidence interval, 0.18-0.99). | 26284593 |
| Inflammation, Prostate | Altered Intercellular Communication | Applying TZPSAD is advantageous in determining rebiopsy strategy in patients with proven inflammation of prostate at initial biopsy. | 26284593 |
| Necrotizing granulomatous inflammation, Malignant Neoplasms | Altered Intercellular Communication | Mediastinal Granulomatous Inflammation and Overall Survival in Patients with a History of Malignancy. | 26284901 |
| Necrotizing granulomatous inflammation, Primary malignant neoplasm | Altered Intercellular Communication | Investigators have postulated that mediastinal granulomatous inflammation is associated with prolonged overall survival in patients with cancer. | 26284901 |
| Necrotizing granulomatous inflammation, Primary malignant neoplasm | Altered Intercellular Communication | We sought to determine whether mediastinal granulomatous inflammation affects overall survival in patients with a history of treated cancer. | 26284901 |
| Mediastinal lymphadenopathy, Granuloma, Primary malignant neoplasm, Necrotizing granulomatous inflammation | Altered Intercellular Communication | Patients with a history of treated cancer who underwent endobronchial ultrasound-transbronchial needle aspiration (EBUS-TBNA) for evaluation of mediastinal or hilar lymphadenopathy were grouped based on whether they had mediastinal granulomatous inflammation or benign mediastinal lymphadenopathy without granulomas. | 26284901 |
| Necrotizing granulomatous inflammation, Mediastinal lymphadenopathy | Altered Intercellular Communication | We reviewed the records of 106 patients (44 with mediastinal granulomatous inflammation and 62 with benign mediastinal lymphadenopathy). | 26284901 |
| Necrotizing granulomatous inflammation, Mediastinal lymphadenopathy | Altered Intercellular Communication | The 3-year survival rate was 90% overall and 93 and 88% in patients with mediastinal granulomatous inflammation and benign mediastinal lymphadenopathy, respectively (P=0.40). | 26284901 |
| Necrotizing granulomatous inflammation, Mediastinal lymphadenopathy, Cancer-Related Death | Altered Intercellular Communication | After multivariate adjustment, whether patients had mediastinal granulomatous inflammation or benign mediastinal lymphadenopathy did not significantly affect the risk of cancer death (mediastinal granulomatous inflammation to benign mediastinal lymphadenopathy hazard ratio, 1.27; P=0.76). | 26284901 |
| Necrotizing granulomatous inflammation, Primary malignant neoplasm, Mediastinal lymphadenopathy | Altered Intercellular Communication | These results suggest that patients who develop mediastinal granulomatous inflammation after cancer treatment do not have an increased overall survival when compared with patients who develop benign mediastinal lymphadenopathy. | 26284901 |
| Airway structure | Altered Intercellular Communication | Systemic response to bacterial colonisation and immune complex deposition secondary to chronic airway inflammation is thought to be underlying mechanism of the disease. | 26284926 |
| Inflammation, Sarcopenia | Altered Intercellular Communication | Previous studies have found inflammation, growth factors, and androgen signaling pathways all contribute to sarcopenia. | 26286594 |
| Inflammation, Uveitis | Altered Intercellular Communication | The patients had statistically significant fewer episodes of anterior uveitis, shorter duration of episodes and fewer total days of inflammation per year while on topical cyclosporine 0.05%. | 26286822 |
| Inflammation, Asthma | Altered Intercellular Communication | TSLP may be used as a biomarker for inflammation in pediatric asthma patients. | 26287664 |
| Airway structure | Altered Intercellular Communication | Fractional concentration of exhaled nitric oxide (FeNO) is a known marker of airway inflammation. | 26287987 |
| Inflammation | Altered Intercellular Communication | These data indicate that 20 min of intradialytic exercise have modest effect in systemic inflammation. | 26288101 |
| Airway structure, Craniosynostosis | Altered Intercellular Communication | Fractionated exhaled nitric oxide (FeNO) levels were reportedly elevated in some asthmatics with CRS after adequate treatment, suggesting that residual eosinophilic airway inflammation or ECRS might affect FeNO levels. | 26288109 |
| airway disease, Asthma, Craniosynostosis, Eosinophilic inflammation | Altered Intercellular Communication | There is a possibility of having comorbid ECRS, particularly in asthmatics with high FeNO levels even after adequate treatment, including ICS, suggesting that asthma and ECRS may be closely associated as one airway disease with eosinophilic inflammation. | 26288109 |
| Inflammation, Chronic Kidney Diseases | Altered Intercellular Communication | Chronic kidney disease (CKD) may lead to reduced concentrations of high-density lipoprotein (HDL) and its subfractions (HDL2 and HDL3), and damage them via inflammation and oxidative stress. | 26289085 |
| Inflammation, Necrotizing Scleritis, Avascular Necrosis, CTCAE | Altered Intercellular Communication | Necrotizing scleritis is an immune-mediated ocular inflammatory process, characterized by an area of avascular necrosis and a profound inflammation of the sclera and episclera. | 26290030 |
| Intestinal metaplasia, Inflammation, Carditis, Atrophic | Altered Intercellular Communication | Histologically, the columnar epithelium of squamocolumnar junction, presence and severity of acute and chronic inflammation, atrophy, intestinal metaplasia, and presence of carditis were evaluated. | 26290639 |
| Inflammation, Carditis, Gastro-esophageal reflux disease with esophagitis, Certified Midwife | Altered Intercellular Communication | The inflammation of CM, "carditis", showed a statistically significant association with endoscopic diagnosis of reflux esophagitis according to the LA classification (P = 0.008). | 26290639 |
| Inflammation, Hemorrhage, Superficial ulcer, Numerous, Anastomosis - action, Edema, Exudate | Altered Intercellular Communication | Endoscopic examination revealed an anastomotic stricture; signs of inflammation, including redness, erosion, edema, bleeding, friability, and exudate with white plaques; and multiple depressions in the residual esophagus. | 26290650 |
| Inflammation | Altered Intercellular Communication | Seven weeks later, endoscopic examination revealed improvement in the mucosal inflammation; only the pseudodiverticulosis remained. | 26290650 |
| Inflammation, Stenosis | Altered Intercellular Communication | At the latest follow-up, the patient was symptom-free and the pseudodiverticulosis remained in the residual esophagus without any signs of stricture or inflammation. | 26290650 |
| Intestinal metaplasia, Inflammation, Calf muscle pseudohypertrophy | Altered Intercellular Communication | Upon review of these 18 biopsies, the most common histologic findings were heavy full-thickness or deep lamina propria chronic inflammation (12), inflammatory destruction of oxyntic glands (12), metaplasia (intestinal, pyloric, or pancreatic acinar) (10), prominent lamina propria eosinophils (8), and parietal cell pseudohypertrophy (4). | 26291507 |
| Inflammation, Metaplasia | Altered Intercellular Communication | When metaplasia, full-thickness chronic inflammation, and/or oxyntic destruction are seen, a note suggesting laboratory testing and/or close clinical follow-up in this subset of patients may be warranted. | 26291507 |
| Inflammation, Primary malignant neoplasm | Altered Intercellular Communication | Increasing evidence suggests a close relationship between systemic inflammation and cancer development and progression. | 26292807 |
| Inflammation, Prostate carcinoma | Altered Intercellular Communication | We investigated the influence of markers of systemic inflammation such as leucocyte counts and metabolic co-morbidities on overall survival (OS) after radiotherapy for localized prostate cancer. | 26292807 |
| Inflammation, Prostate carcinoma | Altered Intercellular Communication | Neutrophil count, as a possible marker of systemic inflammation, appear to be an independent prognostic factor for overall mortality in localized prostate cancer. | 26292807 |
| Inflammation, Psoriasis | Altered Intercellular Communication | RBP-4 might have a protective role in terms of chronic inflammation and comorbidities of psoriasis. | 26293108 |
| Inflammation, Impaired cognition, Data types - Address | Altered Intercellular Communication | The cognitive impairment caused by AD is associated with abnormal accumulation of amyloid-b (Ab) and hyperphosphorylated tau, which are accompanied by inflammation. | 26293123 |
| Primary malignant neoplasm, Chronic inflammation | Altered Intercellular Communication | Patients with chronic inflammation, such as cancer, have been shown to have pathological clot structures with modulated mechanical properties. | 26293709 |
| Inflammation, Behavior, Neoplasms | Altered Intercellular Communication | Nevertheless, the tumorous behavior points to a continuity between inflammation and neoplasia. | 26293797 |
| Gingivitis, Hemorrhage | Altered Intercellular Communication | One hundred twenty participants (non-dental students) with a moderate gingival inflammation (bleeding on probing at 40-70 % of test sites) were included in this randomized controlled double blind clinical trial. | 26293981 |
| Cytomegalovirus Infections, Inflammation | Altered Intercellular Communication | Histological features of CMV graft infection include: (1) stromal keratocytes with cytopathic changes; (2) lack of inflammation, only occasional macrophages present and (3) absence of vascularisation. | 26294107 |
| Kidney Failure, Chronic, Inflammation | Altered Intercellular Communication | Inflammation and the bone-vascular axis in end-stage renal disease. | 26294291 |
| Kidney Failure, Chronic, Inflammation | Altered Intercellular Communication | Parameters of inflammation and mineral metabolism were assessed in 81 ESRD patients (55 +- 13 year, 68 % male) referred for renal transplantation. | 26294291 |
| Inflammation, Calcification of the aorta, Diabetes Mellitus | Altered Intercellular Communication | Low bone area associated with aortic calcification, independent of age, diabetes, and inflammation. | 26294291 |
| Inflammation, Calcification of the aorta | Altered Intercellular Communication | Low bone area and inflammation associates with aortic calcification, independent of each other and traditional risk factors. | 26294291 |
| Schizophrenia, Inflammation | Altered Intercellular Communication | The chronic schizophrenia group showed significant elevations in the combined inflammation score compared with controls. | 26294704 |
| Schizophrenia, Inflammation | Altered Intercellular Communication | Consistent with these findings, the chronic schizophrenia group had significantly increased odds of a combined inflammation score greater than the 75th and the 90th percentile of that of the controls. | 26294704 |
| Inflammation, Atherosclerosis | Altered Intercellular Communication | Life course socioeconomic status and DNA methylation in genes related to stress reactivity and inflammation: The multi-ethnic study of atherosclerosis. | 26295359 |
| Inflammation, Prostatic Intraepithelial Neoplasias | Altered Intercellular Communication | Twelve biopsies yielded nonmalignant results (60%): high-grade prostatic intraepithelial neoplasia (n = 3) or benign prostatic tissue with or without inflammation (n = 9). | 26295644 |
| Intraocular inflammation, Edema | Altered Intercellular Communication | Associated ocular features included retinal pigment epithelial changes (67%), intraocular inflammation (55%), subretinal fluid (50%), macular edema (50%), and choroidal folds (30%). | 26296144 |
| Intraocular inflammation | Altered Intercellular Communication | It can produce intraocular inflammation in 50% of the cases and may be painless in 25%. | 26296144 |
| Gingivitis, Dental caries | Altered Intercellular Communication | Negative binomial regression model of permanent tooth caries found higher rates of caries in children who were from non-fluoridated areas (RR 2.1); Aboriginal (RR 2.4); had gingival inflammation (RR 1.5); lower ICSEA level (RR 1.4); and recalled at more than 24-month interval (RR 1.8). | 26296432 |
| Malignant tumor of colon, Inflammation, Neoplasms | Altered Intercellular Communication | In colon cancer, IL-17-driven inflammation promotes tumor progression, whereas IFN-g production is essential for antitumor immunity. | 26297765 |
| Inflammation, Endothelial dysfunction | Altered Intercellular Communication | Visfatin has been described as a marker of inflammation and endothelial dysfunction, but whether circulating visfatin levels are predictive to a subsequent decline in renal function remains unclear. | 26298010 |
| Inflammation | Altered Intercellular Communication | The diverticulum in our case appeared to have a thickened wall on imaging but no signs of acute inflammation were present on the CT scan or noticed intraoperatively. | 26298012 |
| Inflammation, Abscess | Altered Intercellular Communication | Ultimately, the surgical pathology revealed acute inflammation and focal abscess. | 26298012 |
| Inflammation, Hyponatremia | Altered Intercellular Communication | Hyponatremia was associated with inflammation, NT-proBNP, low muscle mass and alkaline phosphatase; these factors contributed to the increased total mortality associated with hyponatremia but did not explain the increased risk of CVD events associated with hyponatremia or low normal sodium concentration. | 26298426 |
| Inflammation, Refractory anemias, Autoimmune Diseases, Synovial joint structure, Rheumatoid Arthritis | Altered Intercellular Communication | Rheumatoid arthritis (RA) is a chronic autoimmune disease characterized by inflammation and destruction of synovial joints. | 26298564 |
| Kidney Failure, Chronic, Inflammation, Sarcopenia, Cardiovascular Diseases | Altered Intercellular Communication | In end-stage renal disease, deleterious effect of sarcopenia on cardiovascular disease has been explained mainly by chronic inflammation. | 26298738 |
| Airway structure, Chronic Obstructive Airway Disease, Sleep Apnea, Obstructive | Altered Intercellular Communication | Obstructive sleep apnea exacerbates airway inflammation in patients with chronic obstructive pulmonary disease. | 26298789 |
| ARCN1 gene, Airway structure | Altered Intercellular Communication | It has an increased rate of hospitalization due to COPD exacerbation which is believed to indicate a worsening of the underlying chronic airway inflammation. | 26298789 |
| Airway structure, ARCN1 gene, Osage language | Altered Intercellular Communication | Therefore, the aim of this prospective study was to explore whether OSA exacerbates airway inflammation in subjects with COPD by examining the bronchoalveolar lavage (BAL) fluid. | 26298789 |
| Airway structure | Altered Intercellular Communication | After CPAP treatment, airway inflammation was found to decrease significantly. | 26298789 |
| Airway structure, Hypoxemia | Altered Intercellular Communication | CPAP treatment can improve nocturnal hypoxemia and decrease airway inflammation. | 26298789 |
| Inflammation, Malignant Neoplasms | Altered Intercellular Communication | Growing evidence indicated inflammation was linked to the progression and prognosis of many malignancies. | 26299079 |
| Inflammation, Thyroid Diseases, Malignant Neoplasms | Altered Intercellular Communication | Erythrocyte sedimentation rate (ESR) and C-reactive protein (CRP), as two inflammation markers, reported frequently in the incidence and progress of solid cancers, but little research has concerned these markers in thyroid disease. | 26299079 |
| Edema of bone marrow | Altered Intercellular Communication | Fifty-six other RA-patients of the EAC-cohort underwent baseline MRIs of wrist, MCP and MTP-joints; MRI-inflammation (RAMRIS-synovitis plus bone marrow edema) was also evaluated in mediation analyses. | 26299443 |
| Damage | Altered Intercellular Communication | The association of age with joint damage (b=1.032, p=0.004) decreased after also including the MRI-inflammation-score (b=1.025, p=0.021), suggesting partial mediation. | 26299443 |
| Damage | Altered Intercellular Communication | RA-patients presenting at higher age have more severe joint damage; this might be partially explained by more severe MRI-detected inflammation at higher age. | 26299443 |
| Inflammation, Neoplasms | Altered Intercellular Communication | Chronic inflammation triggers DNA damage and oncogenic mutations and causes tumor formation and tumor progression. | 26299699 |
| Inflammation, Cardiovascular Diseases | Altered Intercellular Communication | Beta-adrenergic receptor mediated inflammation control by monocytes is associated with blood pressure and risk factors for cardiovascular disease. | 26300225 |
| Amyotrophic Lateral Sclerosis | Altered Intercellular Communication | Complex Inflammation mRNA-Related Response in ALS Is Region Dependent. | 26301107 |
| Refractory anemias, Inflammation | Altered Intercellular Communication | Further, increased expression of Sema4A is required to promote inflammation of RA. | 26303122 |
| Inflammation, Diabetes Mellitus, Non-Insulin-Dependent | Altered Intercellular Communication | In people with type 2 diabetes, variations in the proportion of fat and carbohydrates of the diet, within the relatively narrow ranges recommended by different nutritional guidelines, significantly impact on the metabolic profile and markers of low-grade inflammation. | 26303195 |
| Inflammation, Hypoxia | Altered Intercellular Communication | The Human Carotid Body Gene Expression and Function in Signaling of Hypoxia and Inflammation. | 26303502 |
| Inflammation, Hypoxia | Altered Intercellular Communication | We conclude that by releasing pro- and anti-inflammatory cytokines during hypoxia the human carotid body displays a structural and functional capacity to participate in sensing and mediating systemic inflammation. | 26303502 |
| Ischemia, Thrombosis, Hemorrhage, Rupture, Meningitis | Altered Intercellular Communication | The mechanism appears to be the spread of meningeal inflammation to involve the walls of intracranial vessels, resulting in arterial thrombosis with ischemia or rupture with hemorrhage. | 26304069 |
| Inflammation, Carcinogenesis | Altered Intercellular Communication | Inflammation and oxidative stress play important roles in colorectal carcinogenesis. | 26304464 |
| Inflammation, Adenoma of large intestine | Altered Intercellular Communication | Overall, our results provide no evidence that calcium supplementation favorably modulates concentrations of circulating biomarkers of inflammation or oxidative stress over 4 months among patients with a previous colorectal adenoma. | 26304464 |
| Inflammation, Hypertension, CTCAE, Diarrhea | Altered Intercellular Communication | The most frequent AEs were diarrhea (cohort A, 74%; cohort B, 67%), mucosal inflammation (cohort A, 49%; cohort B, 60%), and hypertension (cohort A, 52%; cohort B, 45%). | 26304872 |
| Inflammation, Neuritis, Skin lesion, Swelling, physiopathological | Altered Intercellular Communication | Type 1 reactions are typical of borderline cases and occur in 30% of patients and present as swelling and inflammation of existing skin lesions, neuritis, and nerve dysfunction. | 26304919 |
| methyldopa, Inflammation, Blindness | Altered Intercellular Communication | Age-related macular degeneration (AMD) is the leading cause of irreversible blindness in the elderly of industrialized nations, and there is increasing evidence to support a role for chronic inflammation in its pathogenesis. | 26305120 |
| Gastrointestinal inflammation | Altered Intercellular Communication | FOXP3+ regulatory T cells (Tregs) are critical for preventing intestinal inflammation. | 26305224 |
| Radiofrequency Ablation, Inflammation, FAM126A gene | Altered Intercellular Communication | These data demonstrate that circulating histones are excessively released in HCC patients treated with RFA, which may lead to systemic inflammation by stimulating neutrophil activation and promoting cytokine production. | 26305424 |
| Radiofrequency Ablation, Inflammation | Altered Intercellular Communication | Circulating histones may act as a novel marker to indicate the extent of inflammation related to RFA. | 26305424 |
| Cataract | Altered Intercellular Communication | Molecular Inflammation in the Contralateral Eye After Cataract Surgery in the First Eye. | 26305528 |
| Benign prostatic hypertrophy, prostatitis | Altered Intercellular Communication | Chronic prostatic inflammation (CPI) could be a cause of symptomatic or complicated benign prostatic hyperplasia (BPH). | 26306400 |
| Acute Coronary Syndrome, Cerebrovascular accident | Altered Intercellular Communication | Concurrent Carotid Inflammation in Acute Coronary Syndrome as Assessed by (18)F-FDG PET/CT: A Possible Mechanistic Link for Ischemic Stroke. | 26306455 |
| Inflammation, GDC AJCC Clinical Stage Terminology | Altered Intercellular Communication | During follow-up, 3 cerebrovascular events occurred in ACS patients (including 1 early IS in a patient with severe baseline carotid inflammation), whereas none in CSA patients (P = .057). | 26306455 |
| GDC AJCC Clinical Stage Terminology | Altered Intercellular Communication | This study provided in vivo evidence that ACS survivors might experience concurrent carotid arterial inflammation. | 26306455 |
| Inflammation, physiopathological, Cardiovascular Diseases | Altered Intercellular Communication | Vascular endothelial function declines with advancing age, due in part to increased oxidative stress and inflammation, and this age-related vascular dysfunction has been identified as an independent risk factor for cardiovascular diseases. | 26306566 |
| Inflammation, Enophthalmos | Altered Intercellular Communication | CT showed right enophthalmos, a post-inflammatory change and chronic inflammation. | 26306741 |
| Inflammation, Atherosclerosis, Hyperglycemia, GDC AJCC Clinical Stage Terminology | Altered Intercellular Communication | Inflammation plays a critical role in the progression of atherosclerosis, and hyperglycemia is a common feature in patients with ACS. | 26307104 |
| Inflammation, GDC Disease Response Terminology | Altered Intercellular Communication | DR pathogenesis has not been fully elucidated, but inflammation is widely accepted to play an important role. | 26308022 |
| Inflammation | Altered Intercellular Communication | Chronic inflammation and oxidative stress might be considered the key mechanisms of aging. | 26308091 |
| palladium, Nerve Degeneration | Altered Intercellular Communication | However, the association between long-term systemic inflammations and neurodegeneration has not been assessed in PD patients. | 26308525 |
| palladium, Presenile dementia, Nerve Degeneration | Altered Intercellular Communication | These associations were independent of sex, age, PD severity, dementia, and anti-Parkinsonian agents, suggesting that subclinical systemic inflammations could accelerate neurodegeneration in PD. | 26308525 |
| Inflammation | Altered Intercellular Communication | The association between subgingival periodontal pathogens and systemic inflammation. | 26309048 |
| Inflammation, Periodontal Diseases | Altered Intercellular Communication | To investigate associations between periodontal disease pathogens and levels of systemic inflammation measured by C-reactive protein (CRP). | 26309048 |
| Inflammation | Altered Intercellular Communication | The association between interleukin 8 with nonphysical domains in patients with 6MWD < 350 m suggests that inflammation may play a larger role in the perceptive domain than previously recognized. | 26309192 |
| Inflammation, Myocardial | Altered Intercellular Communication | Abundant myocardial edema without evidence of acute inflammation was detected in cardiac tissue postmortem in one patient. | 26310790 |
| Degenerative polyarthritis, Inflammation | Altered Intercellular Communication | OA synovium was stratified by histological inflammation grade using index tissue sections. | 26311062 |
| Inflammation, Atherosclerosis | Altered Intercellular Communication | Arterial wall properties and inflammation are key players in atherosclerosis development. | 26311225 |
| Inflammation, Benign prostatic hypertrophy | Altered Intercellular Communication | Role of inflammation in benign prostatic hyperplasia development among Han Chinese: A population-based and single-institutional analysis. | 26311564 |
| Asymptomatic Inflammatory Prostatitis, prostatitis | Altered Intercellular Communication | In terms of histopathological analysis, benign prostatic hyperplasia/asymptomatic inflammatory prostatitis patients were more likely to show mild (53%), focal (67%) and stromal (40%) prostatic inflammation in our study. | 26311564 |
| Inflammation, Rheumatoid Arthritis | Altered Intercellular Communication | Analysis of distribution and severity of inflammation in patients with osteoarthitis compared to rheumatoid arthritis by ICG-enhanced fluorescence optical imaging and musculoskeletal ultrasound: a pilot study. | 26311723 |
| Inflammation | Altered Intercellular Communication | Joint inflammation can be visualised by fluorescence optical imaging (FOI) and musculoskeletal ultrasound (US). | 26311723 |
| Inflammation | Altered Intercellular Communication | Joint inflammation was graded by a semiquantitative score (0-3) for each imaging method. | 26311723 |
| Refractory anemias, Inflammation, Degenerative polyarthritis | Altered Intercellular Communication | US and FOI detected inflammation in both RA and OA highlighting the inflammatory component in the course of OA. | 26311723 |
| Inflammation, Acute Cholecystitis | Altered Intercellular Communication | Imaging features of acute cholecystitis have been described in the literature and are variable, depending on the stage of inflammation. | 26311909 |
| Communicable Diseases, Lichen Sclerosus et Atrophicus | Altered Intercellular Communication | The etiology of lichen sclerosus is multifactorial, with participation of genetic, autoimmune, infectious and hormonal factors. | 26312692 |
| Polyarteritis Nodosa, Inflammation, Vasculitis, CTCAE | Altered Intercellular Communication | Polyarteritis nodosa is a rare vasculitis in children characterized by necrotizing inflammation in small and medium size arteries. | 26312712 |
| Inflammation, Damage, Rheumatoid Arthritis | Altered Intercellular Communication | MRI evidence of persistent joint inflammation and progressive joint damage despite clinical remission during treatment of early rheumatoid arthritis. | 26313244 |
| Inflammation, Superficial ulcer | Altered Intercellular Communication | MRI at baseline detected inflammation in joints and tendons in all patients as well as erosions in 10 out of 13 patients. | 26313244 |
| Damage | Altered Intercellular Communication | The MRI changes showed that joint damage started early and continued in the presence of persistent synovial and tenosynovial inflammation. | 26313244 |
| Inflammatory Bowel Diseases, Inflammation | Altered Intercellular Communication | Inflammatory bowel disease (IBD) is characterized by a chronic inflammation of the gut, partly driven by defects in the innate immune system. | 26313692 |
| palladium, Inflammation, Malnutrition, Periodontal Diseases | Altered Intercellular Communication | Periodontal disease (PD) is prevalent and correlated with malnutrition and inflammation in patients on hemodialysis (HD). | 26313800 |
| Primary hypogonadism | Altered Intercellular Communication | The gonads also have poor hormonal activity (hypergonadotropic hypogonadism) in most of the pubertal/adult patients. | 26314751 |
| Refractory anemias, Inflammation, Rheumatoid Arthritis, Diabetes Mellitus | Altered Intercellular Communication | Low-grade inflammation conditions, e.g., type 2 diabetes, have been shown to be associated with an increased risk of rheumatoid arthritis (RA). | 26314811 |
| Dermatitis, Atopic, Asthma, IL13 gene | Altered Intercellular Communication | However, the association between other chronic inflammatory conditions, e.g., asthma, allergic rhinitis, and atopic dermatitis, is still unclear. | 26314811 |
| Inflammation, Sleep Apnea, Obstructive, Osage language | Altered Intercellular Communication | Previous studies have shown a relationship between obstructive sleep apnea (OSA) and erythrocyte sedimentation rate (ESR), a representative marker for inflammation. | 26315467 |
| Inflammation, Asthma, Allergic | Altered Intercellular Communication | Adiponectin does not protect against the development of inflammation in the setting of asthma and may in fact exacerbate the disease via its anti-TH1 inflammatory effects, allowing for increased TH2 differentiation and a more severe allergic response. | 26315710 |
| Inflammation, Brain | Altered Intercellular Communication | The gradually evolving focal neurological signs and underlying immunosuppression raised the possibility of localized cerebral infection or inflammation. | 26315723 |
| Cancer-related fatigue, Inflammation | Altered Intercellular Communication | There was no difference in PWV, cIMT, CRF or in markers of systemic inflammation in the patients with KD (CAA+ or CAA-) compared with HC. | 26316045 |
| Refractory anemias, Inflammation | Altered Intercellular Communication | We emphasize the unusual spontaneous and sustained joint remission without specific treatment, and the development of severe extra-articular manifestations of RA in absence of concomitant articular activity, as well as the importance of controlling inflammation. | 26316106 |
| Inflammation, Gastritis, Atrophic | Altered Intercellular Communication | Positive relationship between p42.3 gene and inflammation in chronic non-atrophic gastritis. | 26316259 |
| Stomach Carcinoma, Neoplasms | Altered Intercellular Communication | Gastric cancer (GC) is a typical type of inflammation-related tumor. | 26316259 |
| Gastritis | Altered Intercellular Communication | We aimed to explore the relationship between gastric inflammation and p42.3 gene in vitro and in vivo. | 26316259 |
| Infection caused by Helicobacter pylori, Inflammatory disease of mucous membrane | Altered Intercellular Communication | In addition, p42.3 gene expression was positively associated with the severity of gastric mucosal inflammation and H. pylori infection (P = 0.000). | 26316259 |
| Gastritis | Altered Intercellular Communication | Its expression was significantly more common in severe gastric inflammation and in H. pylori-infected cases. | 26316259 |
| Infection caused by Helicobacter pylori, Inflammatory disease of mucous membrane | Altered Intercellular Communication | p42.3 gene expression is associated with gastric mucosal inflammation that can be upregulated by TNF-a and H. pylori infection. | 26316259 |
| Electrocardiogram: myocardial infarction (finding), atherosclerotic | Altered Intercellular Communication | Systemic Atherosclerotic Inflammation Following Acute Myocardial Infarction: Myocardial Infarction Begets Myocardial Infarction. | 26316523 |
| atherosclerotic | Altered Intercellular Communication | The presence and extent of MI is associated with increased aortic atherosclerotic inflammation and early recurrent MI. | 26316523 |
| Dental Plaque, atherosclerotic | Altered Intercellular Communication | This finding supports the hypothesis that acute MI exacerbates systemic atherosclerotic inflammation and remote plaque destabilization: MI begets MI. | 26316523 |
| Inflammation, Sleep Apnea, Obstructive, Endothelial dysfunction | Altered Intercellular Communication | There is growing research evidence suggesting the presence of endothelial dysfunction and systemic inflammation in patients with obstructive sleep apnea syndrome (OSAS). | 26316731 |
| Prediabetes syndrome, Bipolar Disorder | Altered Intercellular Communication | Hormonal determinants of the severity of andropausal and depressive symptoms in middle-aged and elderly men with prediabetes. | 26316733 |
| palladium, Bipolar Disorder | Altered Intercellular Communication | Hormonal determinants of andropausal and depressive symptoms are different in middle-aged and elderly patients, but endocrine tests are necessary in all men with PD. | 26316733 |
| Inflammatory Bowel Diseases, Inflammation, Leukocytosis, Fever, CTCAE, Primary Biliary Cholangitis, Cryopyrin-Associated Periodic Syndromes, "Sjogrens Syndrome", Arthritis, Juvenile-Onset Still Disease, Lupus Erythematosus | Altered Intercellular Communication | Included were cases of Schnitzler syndrome, Still disease, systemic lupus erythematosus, Sjogren syndrome, cryopyrin-associated periodic syndrome, primary biliary cirrhosis, inflammatory bowel disease, and those that had signs of systemic inflammation not otherwise specified, that is, fever, arthritis, leukocytosis, and elevated erythrocyte sedimentation rate. | 26317390 |
| Icterus, Inflammation, Illness (finding), TYPHUS | Altered Intercellular Communication | In murine typhus, nucleosome levels associated with pro-inflammatory cytokines and the duration of illness, while ELA complexes correlated strongly with inflammation markers, jaundice and increased respiratory rates. | 26317419 |
| Hyperglycemia, Inflammation, Hyperlipidemia, Atherosclerosis | Altered Intercellular Communication | Hyperglycemia, insulin resistance, dislipidemia, oxidative stress and inflammation are well-documented risk factors for subclinical atherosclerosis. | 26318108 |
| Hyperlipidemia, Inflammation | Altered Intercellular Communication | The ORs for insulin resistance, dislipidemia, oxidative stress and inflammation were higher with increasing DPP4 quartiles (P < 0.001 for trend). | 26318108 |
| Anxiety, CTCAE 3.0, Inflammation, Depression, CTCAE | Altered Intercellular Communication | Participants completed self-reported measures of family and marital functioning, anxiety and depression (biobehavioral reactivity), number of chronic health conditions, number of prescribed medications, and a biological protocol in which the following indices were obtained: cardiovascular functioning, sympathetic and parasympathetic nervous system activity, hypothalamic pituitary adrenal axis activity, inflammation, lipid/fat metabolism, and glucose metabolism. | 26318212 |
| Cessation of life, Inflammation, Data types - Address | Altered Intercellular Communication | Multiple cellular processes including regulation of amyloid-b peptide, tau, inflammation, and cell death have been suggested to associate with AD, but it remains largely unknown if long noncoding RNAs (lncRNAs) may be playing a role in AD pathogenesis. | 26318290 |
| Inflammation, Restenosis | Altered Intercellular Communication | The molecular basis of restenosis is intensively associated with inflammation. | 26318748 |
| Inflammation, Chronic Kidney Diseases | Altered Intercellular Communication | due to the relevance of inflammation in individuals with chronic kidney disease (CKD), inflammation should be taken into account in the interpretation of the clinical-nutritional status. | 26319862 |
| Inflammation, Chronic Kidney Diseases | Altered Intercellular Communication | assess the association between inflammation, nutritional and clinical parameters in patients with CKD. | 26319862 |
| Inflammation, Hypoalbuminemia | Altered Intercellular Communication | In the group with inflammation, 05 (33%) had hypoalbuminemia as compared with 05 (6.5%) in the group without inflammation (p = 0.002). | 26319862 |
| Inflammation, Hypoalbuminemia | Altered Intercellular Communication | inflammation was associated with changes in the total cholesterol and LDL levels and with an increased incidence of hypoalbuminemia. | 26319862 |
| Postoperative endophthalmitis, Retinal Detachment, Acute inflammation, Suprachoroidal hemorrhage | Altered Intercellular Communication | There were no cases of postoperative endophthalmitis, suture erosion/breakage, retinal detachment, suprachoroidal haemorrhage, uveitis-glaucoma-hyphema syndrome or persistent postoperative inflammation in the follow-up period. | 26319945 |
| Inflammation, Injury of liver | Altered Intercellular Communication | Endocannabinoid System Contributes to Liver Injury and Inflammation by Activation of Bone Marrow-Derived Monocytes/Macrophages in a CB1-Dependent Manner. | 26320250 |
| Fibrosis Assessment, Hepatic inflammation | Altered Intercellular Communication | In vivo, inhibition of CB1 attenuated the inflammatory cytokine level through real-time RT-PCR and cytometric bead array, ameliorating hepatic inflammation and fibrosis. | 26320250 |
| Fibrosis Assessment, Hepatic inflammation | Altered Intercellular Communication | In this study, we identify inactivation of BMM-expressed CB1 as a therapeutic strategy for reducing hepatic inflammation and fibrosis. | 26320250 |
| Inflammation | Altered Intercellular Communication | As such, the cerebral capillary endothelium represents an important target for the peripheral estrogen neuroprotective functions, leading us to hypothesize that estrogen can limit BBB breakdown following the onset of peripheral inflammation. | 26321046 |
| Myelofibrosis, Colonization, Bone necrosis, Suppurative inflammation, Osteonecrosis of Jaw, Actinomyces | Altered Intercellular Communication | The typical histological aspects of ONJ were predominantly osteonecrosis, bone marrow fibrosis, and bacterial colonization (Actinomyces) with suppurative inflammation. | 26321065 |
| ARCN1 gene, Chronic Obstructive Airway Disease, Airway structure | Altered Intercellular Communication | Chronic obstructive pulmonary disease (COPD) is characterized by neutrophilic airway inflammation. | 26321138 |
| Airway structure | Altered Intercellular Communication | WNT/b-catenin signaling regulates cigarette smoke-induced airway inflammation via the PPARd/p38 pathway. | 26322419 |
| Airway structure, ARCN1 gene, Chronic Obstructive Airway Disease | Altered Intercellular Communication | The mechanisms of WNT/b-catenin signaling involved in airway inflammation of chronic obstructive pulmonary disease (COPD) remain unknown, although recent observations have suggested an important contribution of the pathway in pulmonary parenchymal tissue repair and airway epithelium differentiation. | 26322419 |
| Airway structure, ARCN1 gene | Altered Intercellular Communication | Taken together, our findings indicate that the reduced activity of WNT/b-catenin signaling induced by CS may promote inflammatory cytokine production in airway epithelium and have an essential role in airway inflammation in COPD by PPARd/p38 MAPK pathway. | 26322419 |
| Crohn Disease | Altered Intercellular Communication | Contrast Enhanced Abdominal Ultrasound in the Assessment of Ileal Inflammation in Crohn's Disease: A Comparison with MR Enterography. | 26322970 |
| Inflammatory disease of mucous membrane | Altered Intercellular Communication | Optimal diagnostic accuracy in CEUS was obtained at a peak intensity value of 10%, showing 100% sensitivity, 92% specificity and an accuracy of 99% in demonstrating ileal mucosal inflammation. | 26322970 |
| Inflammation, Carcinogenesis | Altered Intercellular Communication | Chronic inflammation plays an important role in lung carcinogenesis. | 26323323 |
| Inflammation, Carcinoma of lung, Obesity | Altered Intercellular Communication | Few prospective studies have examined associations between lung cancer, serum C-reactive protein (CRP), a measure of systemic inflammation, and inflammatory lifestyle factors, such as smoking and obesity. | 26323323 |
| Inflammation, Carcinoma of lung | Altered Intercellular Communication | Is the exhaled breath temperature in lung cancer influenced by airways neoangiogenesis or by inflammation? | 26323590 |
| Inflammation, Primary malignant neoplasm, Fatigue | Altered Intercellular Communication | Fatigue in Patients With Advanced Terminal Cancer Correlates With Inflammation, Poor Quality of Life and Sleep, and Anxiety/Depression. | 26324072 |
| Inflammation, Primary malignant neoplasm, Fatigue | Altered Intercellular Communication | In patients with advanced cancer, fatigue is a common symptom associated with the presence of inflammation, poor quality of sleep, depression/anxiety, and poor quality of life. | 26324072 |
| Inflammation, Anemia | Altered Intercellular Communication | Anemia in this setting appears multifactorial such that chronic inflammation and iron deficiency need to be addressed together as part of integrated management of childhood anemia. | 26324733 |
| Inflammation, Atrial Fibrillation, Hyperuricemia, Gout | Altered Intercellular Communication | Recent studies suggest an association between inflammation, hyperuricaemia and AF, but little is known whether gout is associated with AF risk. | 26324846 |
| Inflammation | Altered Intercellular Communication | The role of inflammation in psychopathology has received great attention over the past decades. | 26325024 |
| Inflammation, Psychiatric | Altered Intercellular Communication | Results show elevated inflammation markers from the innate immune system across C&A acute psychiatric diagnosis, and suggest a link between psychopathology, inflammation and stress. | 26325024 |
| Inflammation, Carcinogenesis | Altered Intercellular Communication | Immune response-related genes play a major role in colorectal carcinogenesis by mediating inflammation or immune-surveillance evasion. | 26325386 |
| PROS1 gene, Arthritis, Arthritis, Psoriatic | Altered Intercellular Communication | This study aims to evaluate the application of fIRI in Psoriatic Arthritis (PsA) assessment, evaluating the thermoregulatory alterations due to joint inflammation in PsA patients both in basal conditions and after a mild functional (isometric) exercise; fIRI outcomes were compared with those provided by Power Doppler Ultrasonography (PWD-US). | 26327581 |
| Inflammation, Colorectal Carcinoma | Altered Intercellular Communication | Oxidative stress linked with chronic inflammation is associated with etiology of the colorectal cancer. | 26329524 |
| Inflammation, Colorectal Carcinoma | Altered Intercellular Communication | Urinary DNA modifications may reflect the oxidative stress/chronic inflammation in colorectal cancer but diagnostic performance for early-detection is moderate. | 26329524 |
| Inflammation, Atresia, Tuberculosis | Altered Intercellular Communication | The atresia of the superior segmental bronchus was histologically considered to be acquired atresia due to the inflammation from tuberculosis. | 26329627 |
| Inflammation, Nephrotic Syndrome, Minimal Change | Altered Intercellular Communication | Inflammation is a key part in the etiology and progression of idiopathic nephrotic syndrome (INS), we hypothesize that removing pro-inflammatory cytokines with intermittent high-volume hemofiltration (IHVHF) could improve the outcome in INS patients. | 26329674 |
| Fibrosis Assessment, Hepatitis | Altered Intercellular Communication | Long-Term Telbivudine Treatment Results in Resolution of Liver Inflammation and Fibrosis in Patients with Chronic Hepatitis B. | 26329749 |
| Fibrosis Assessment, Hepatitis | Altered Intercellular Communication | After antiviral treatment (median duration: 261 weeks), liver histology improved with increased proportions of patients with absence/minimal liver inflammation (Knodell necroinflammatory score <=3), from 16% (9/57) at baseline to 98% (56/57), and absence/minimal fibrosis (Ishak score <=1), from 25% (14/57) at baseline to 84% (48/57). | 26329749 |
| Gastrointestinal inflammation, Visceral Pain | Altered Intercellular Communication | Recent studies implicate TRPV4 receptors in visceral pain signaling and intestinal inflammation. | 26330151 |
| Pain Distress Question, Gastrointestinal inflammation | Altered Intercellular Communication | * Recent studies implicate TRPV4 in pain signaling and intestinal inflammation. | 26330151 |
| Inflammation, Fibrosis Assessment | Altered Intercellular Communication | The matrix metalloproteinase-7 (MMP-7) and osteopontin (OPN) are both multifunctional proteins with roles in inflammation, cell proliferation, tissue remodeling and so on, implicated in the pathogenesis of numerous conditions including pulmonary fibrosis. | 26330178 |
| methyldopa, Inflammation | Altered Intercellular Communication | The pathogenesis of age-related macular degeneration (AMD) is associated with systemic and local inflammation. | 26330750 |
| Retinitis, Bacterial Infections | Altered Intercellular Communication | Various studies suggested that viral or bacterial infection may aggravate retinal inflammation in the aged retina. | 26330750 |
| Retinitis | Altered Intercellular Communication | The data also suggest that selective inhibition of distinct signal transduction pathways or individual transcription factors may not be effective to inhibit viral retinal inflammation. | 26330750 |
| Inflammation, Neoplasms | Altered Intercellular Communication | CD4 (+) T helper 17 (Th17) cells play critical roles in inflammation and tumor development. | 26331819 |
| Chronic Obstructive Airway Disease, Carcinoma of lung | Altered Intercellular Communication | The involvement of Th17 cells in chronic obstructive pulmonary disease (COPD)-type inflammation-associated lung cancer has also been confirmed in animal models. | 26331819 |
| Inflammation, Hyperferritinaemia, Malignant Neoplasms | Altered Intercellular Communication | Hyperferritinemia is common in states of iron overload, inflammation, and malignancy. | 26332484 |
| Inflammation | Altered Intercellular Communication | Uncontrolled complement activation and the release of cell-free heme may result in systemic inflammation, neutrophil activation, and the release of procoagulant neutrophilic proteases. | 26333021 |
| Paroxysmal nocturnal hemoglobinuria, Thrombosis, Inflammation, Cell Death | Altered Intercellular Communication | The increased nucleosome levels in PNH patients with a history of thrombosis suggest systemic inflammation and/or cell death. | 26333021 |
| Primary sclerosing cholangitis, Inflammation, Fibrosis Assessment, Injury of bile duct | Altered Intercellular Communication | Primary sclerosing cholangitis (PSC) is characterized histologically by portal inflammation, bile duct injury and regeneration and concentric periductal fibrosis. | 26333410 |
| Inflammation, Calcinosis, Epithelial cyst | Altered Intercellular Communication | The patients we examined all had scrotal epidermoid cysts in varying stages of inflammation coexisted with scrotal calcinosis. | 26333550 |
| Inflammation, Villous atrophy | Altered Intercellular Communication | It is characterized by chronic inflammation of small intestine associated with villous atrophy. | 26333587 |
| Inflammation, Liver Cirrhosis | Altered Intercellular Communication | B. pseudocatenulatum CECT7765 induces a morphologic, phenotypic and functional transition towards an anti-inflammatory profile in GM-CSF monocyte-derived and AF macrophages from patients with cirrhosis that may help in controlling sustained inflammation in decompensated cirrhosis. | 26334579 |
| RETINOSCHISIS 1, X-LINKED, JUVENILE | Altered Intercellular Communication | Resistant starch (RS) decreases intestinal inflammation in some settings. | 26334878 |
| RETINOSCHISIS 1, X-LINKED, JUVENILE, Inflammation | Altered Intercellular Communication | We tested the hypothesis that gut inflammation will be reduced with dietary supplementation with RS in rural Malawian children. | 26334878 |
| RETINOSCHISIS 1, X-LINKED, JUVENILE, Inflammation | Altered Intercellular Communication | Our findings do not support the hypothesis that RS reduces gut inflammation in rural Malawian children. | 26334878 |
| Inflammation, Vascular calcification, Calcinosis, Cerebral Atherosclerosis, Arterial Stiffness | Altered Intercellular Communication | This occurs not only due to hemodynamic factors but also by systemic ones related to vascular atherosclerosis, inflammation and calcification, which has developed a simple vascular calcification score (SVCS) predictor of vascular calcification and arterial stiffness. | 26336882 |
| Demographics Domain, "Alzheimers Disease", Data types - Address, Inflammation Mediators, Diabetes Mellitus, Non-Insulin-Dependent | Altered Intercellular Communication | The aim of the present study was to evaluate whether there was an inflammation-mediated link between Alzheimer's disease (AD) and type 2 diabetes mellitus (DM) status. | 26337250 |
| Inflammation, Tumor necrosis | Altered Intercellular Communication | Serum inflammation status was evaluated by the determination of serum C-reactive protein (CRP), tumor necrosis factor-alpha, interleukin (IL)-1b and IL-6 levels. | 26337250 |
| Inflammation, Data types - Address | Altered Intercellular Communication | Our findings support the presence of a low-grade systemic inflammation link between AD and DM. | 26337250 |
| Degenerative polyarthritis, Inflammation | Altered Intercellular Communication | The identified genetic variants imply contribution of biological pathways observed in osteoarthritis as well as new pathways, influencing skeletal development and inflammation. | 26337638 |
| Inflammation, Fibrosis Assessment | Altered Intercellular Communication | MicroRNA (miR)-146a and miR-21 have been reported to participate in inflammatory reactions and fibrosis.Excessive inflammation and cardiac fibrosis may play important roles in the development of left ventricular remodeling(LVR). | 26337652 |
| Connective Tissue Diseases | Altered Intercellular Communication | Patients with known connective tissue disorders, systemic inflammatory conditions, dissection, or prior heart surgery were excluded. | 26338050 |
| Abnormal renal function, Inflammation | Altered Intercellular Communication | Hemodialysis patients face oxidative stress and inflammation induced by both kidney dysfunction and hemodialysis procedure. | 26338165 |
| Sepsis, Inflammation, Traumatic injury | Altered Intercellular Communication | Burn injuries are associated with strong inflammation and risk of secondary sepsis which both may affect the function of the glucocorticoid receptor (GR). | 26338204 |
| Refractory anemias, Inflammation | Altered Intercellular Communication | To investigate the effect of suppressing inflammation on retinal microvascular health in patients with RA. | 26338663 |
| Refractory anemias, Inflammation | Altered Intercellular Communication | We demonstrated that suppression of inflammation in RA is associated with a reduction of retinal venular calibre, suggesting that therapies targeting inflammation could improve vascular health in RA. | 26338663 |
| Crohn Disease, Inflammation | Altered Intercellular Communication | This study supports the hypothesis that in Crohn's disease, enteric neurons and glial cells form a functional unit reacting to inflammation by producing PGD2. | 26338799 |
| Crohn Disease | Altered Intercellular Communication | We investigated the expression of PGD2 metabolic pathway actors in Crohn's disease (CD) and the ability of the enteric nervous system (ENS) to produce PGD2 in inflammatory conditions. | 26338799 |
| Inflammation, Endothelium, Choroidal and Ciliary Body Melanoma pT1d TNM Finding v8, GDC Disease Response Terminology | Altered Intercellular Communication | The circulating markers of inflammation, endothelial injury, and TNF signaling are significantly associated with DR in patients with T1D. | 26339132 |
| Refractory anemias, Inflammation, BDI - Functional Impairment, GRN wt Allele | Altered Intercellular Communication | This study demonstrates increased PGRN expression at local sites of inflammation and association between PGRN levels, disease activity, and functional impairment in patients with RA. | 26339140 |
| ARCN1 gene, Inflammation | Altered Intercellular Communication | Although COPD patients exhibited increased inflammation it was not associated with serum retinol. | 26339144 |
| Inflammation, Heart failure, Myocarditis, CTCAE 5.0, Shock, Cardiogenic | Altered Intercellular Communication | Fulminant myocarditis has been defined as the clinical manifestation of cardiac inflammation with rapid-onset heart failure and cardiogenic shock. | 26339181 |
| Peripheral Vascular Diseases, Inflammation, Diabetes Mellitus, Non-Insulin-Dependent | Altered Intercellular Communication | Effects of percutaneous lower-extremity arterial interventions on endothelial function and inflammation response in patients with both type 2 diabetes and lower-extremity peripheral arterial disease. | 26339379 |
| Inflammatory Bowel Diseases, Gastrointestinal inflammation | Altered Intercellular Communication | Fecal lactoferrin, a marker of intestinal inflammation in children with inflammatory bowel disease. | 26339799 |
| Inflammation, Malnutrition | Altered Intercellular Communication | Multivariate Cox proportional analysis showed that the hazards ratio for all-cause mortality was 1.02 (95% CI 1.01-1.04, p=0.006) per 1 mg/l increase in b2-M after adjustment for multiple confounding factors that relate to malnutrition and inflammation marker. | 26339999 |
| Inflammation, Meningitis | Altered Intercellular Communication | These findings suggest that TAFI plays an important role during pneumococcal meningitis, which is likely to be mediated through inhibition of the complement system, and influences the occurrence of systemic complications and inflammation. | 26340319 |
| Inflammation, Primary malignant neoplasm, Cardiovascular Diseases | Altered Intercellular Communication | The concentration, origin and procoagulant properties of circulating microparticles are reported to differ according to pathological settings (inflammation, cancer and cardiovascular diseases). | 26341361 |
| ARCN1 gene, Inflammation | Altered Intercellular Communication | Effective NPPV impacts on systemic inflammation in COPD patients. | 26341549 |
| Cerebral Amyloid Angiopathy, Inflammation, Cerebral microbleeds | Altered Intercellular Communication | The aim of this study is to describe a case of pathologically proven cerebral amyloid angiopathy-related inflammation (CAA-I) without cerebral microbleeds (CMBs) and its clinical course. | 26341733 |
| Inflammation, Fibrosis Assessment, Balloon Dilatation | Altered Intercellular Communication | Thirty-eight (74.5 %) patients had inflammation and 48 (94.1 %) had ballooning degeneration on histology; 29 had fibrosis, of whom 11 had >=F2 fibrosis. | 26341864 |
| Inflammation, Malignant Neoplasms | Altered Intercellular Communication | Markers of systemic inflammation are correlated with patient survival in various cancers. | 26341881 |
| Inflammation, Giant Cell Arteritis | Altered Intercellular Communication | MicroRNA markers of inflammation and remodelling in temporal arteries from patients with giant cell arteritis. | 26342092 |
| Sepsis, Inflammation | Altered Intercellular Communication | IL-35 is elevated in clinical and experimental sepsis and mediates inflammation. | 26342538 |
| Communicable Diseases, Inflammation, Carcinoma of lung | Altered Intercellular Communication | Interleukin (IL)-33 protects against infection and inflammation; however, few studies have explored the relevance of IL-33 in lung cancer patients. | 26342550 |
| Inflammation | Altered Intercellular Communication | Decreased effectiveness of ischemic heart preconditioning in the state of chronic inflammation. | 26342834 |
| Inflammation, Osage language, Atherosclerosis, Hypoxia, physiopathological, Sleep Apnea, Obstructive | Altered Intercellular Communication | Obstructive sleep apnea (OSA) is characterized by repetitive intermittent hypoxia and reoxygenation during sleep with elevated oxidative stress and promotes the development of atherosclerosis, as demonstrated by vascular dysfunction and chronic inflammation. | 26343754 |
| Inflammation | Altered Intercellular Communication | An increased neutrophil to lymphocyte ratio (NLR) has been recognized to be a novel inflammatory biomarker for systemic inflammation. | 26343754 |
| Inflammation, Endothelial dysfunction | Altered Intercellular Communication | The role of endothelial dysfunction and inflammation in this pathophysiological process is not yet clear. | 26343780 |
| ARCN1 gene, Inflammation | Altered Intercellular Communication | Our results showed negative association between peripheral muscle mass (evaluated by CT) and muscle strength and that systemic inflammation has a negative influence in the strength of specific groups of muscles in individuals with stable COPD. | 26345641 |
| Inflammation, Data types - Address | Altered Intercellular Communication | In conclusion, PS decreased cholinesterase, improved memory, and improved hippocampal inflammation injury in AD brains by increasing SOD and OH(-) levels. | 26345866 |
| Autoimmune Diseases, Inflammation | Altered Intercellular Communication | EBV replication induced by chronic inflammation in patients with autoimmune diseases might explain the higher risk of EBV-positive HL. | 26346543 |
| Inflammation, Prediabetes syndrome, Sensory neuropathy, Diabetes Mellitus | Altered Intercellular Communication | Role of inflammation in sensory neuropathy in prediabetes or diabetes. | 26346888 |
| Inflammation, Neuropathy, Prediabetes syndrome, Peripheral Neuropathy | Altered Intercellular Communication | The pro-inflammatory stage and the high incidence of neuropathy in patients with prediabetes may suggest a possible causative effect; however, the potential role of inflammation in the pathogenesis of peripheral neuropathy needs further clarification. | 26346888 |
| Inflammation, Tracheobronchial | Altered Intercellular Communication | A postmortem examination with histology found evidence of active and chronic inflammation as well as destruction of cartilage, in keeping with a diagnosis of relapsing tracheobronchial polychonditis. | 26347233 |
| Inflammation, Lung Diseases, Interstitial | Altered Intercellular Communication | Childhood interstitial lung diseases are rare disorders of largely unknown etiology characterized by variable types and degrees of parenchymal inflammation. | 26347438 |
| Inflammation, Liver Dysfunction | Altered Intercellular Communication | However, IGF-1 is reduced by factors such as inflammation, oxidative stress and liver dysfunction. | 26348017 |
| Inflammation, Liver Dysfunction, Metabolic Syndrome X | Altered Intercellular Communication | But the relationship was dependent on oxidative stress, liver dysfunction and inflammation, suggesting underlying processes by which the metabolic syndrome attenuates IGF-1. | 26348017 |
| Ear Inflammation | Altered Intercellular Communication | Influence of Pneumococcal Conjugate Vaccine on Acute Otitis Media with Severe Middle Ear Inflammation: A Retrospective Multicenter Study. | 26348230 |
| Inflammation, Acute otitis media | Altered Intercellular Communication | In addition, this vaccine may help prevent acute otitis media with severe middle ear inflammation in 1-year-old infants. | 26348230 |
| Inflammation, Diabetes Mellitus | Altered Intercellular Communication | Increased oxidative stress and chronic inflammation participate in the pathogenesis of diabetes. | 26348351 |
| Inflammation, Fibrosis Assessment, Necrosis | Altered Intercellular Communication | Our results provide genetic evidence for a functional cross-talk of Nrf2 and NF-kB/RelA in hepatocytes, which protects the liver from necrosis, inflammation and fibrosis. | 26348541 |
| Typhlitis, Diarrhea | Altered Intercellular Communication | At baseline, Tox-/PCR+ patients had lower C difficile bacterial load and less antibiotic exposure, fecal inflammation, and diarrhea than Tox+/PCR+ patients (P < .001 for all). | 26348734 |
| Inflammation, Primary malignant neoplasm, Malignant Pulmonary Vein Neoplasm | Altered Intercellular Communication | There is a well-established link between inflammation and cancer of various organs, but little data are available on inflammation-associated markers of diagnostic and prognostic clinical utility in pulmonary malignancy. | 26348770 |
| Inflammation | Altered Intercellular Communication | MIF mRNA expression was increased in acutely inflamed adipose tissue indicating the activation of MIF gene transcription in response to adipose tissue inflammation. | 26348853 |
| Inflammation | Altered Intercellular Communication | Our results indicate that increased MIF expression and rapid activation of the MIF gene in fat tissue adjacent to acute wound healing disorders may play a role in cell recruitment to the site of inflammation and wound healing. | 26348853 |
| Sepsis, Inflammation | Altered Intercellular Communication | Hemoadsorption using CytoSorb has gained attention as a potential immunotherapy to control systemic inflammation and sepsis. | 26349530 |
| Inflammation, Bipolar Disorder | Altered Intercellular Communication | Prospective data from the Women's Health Initiative on depressive symptoms, stress, and inflammation. | 26349616 |
| Inflammation, Depression, CTCAE | Altered Intercellular Communication | Combined with previous research, this suggests the relationship between depression, stressful life events and inflammation attenuates with time. | 26349616 |
| Inflammation | Altered Intercellular Communication | Postinfectious, chronic inflammation of the retroperitoneum acts on the ureteral and peri-ureteral tissues, inducing an inflammatory and then a fibrotic process. | 26350043 |
| Blood Glucose, Diabetes Mellitus | Altered Intercellular Communication | Fluctuation in glycemia due to hormonal changes, growth periods, physical activity, and emotions make diabetes management difficult during adolescence. | 26350209 |
| Inflammation, Traumatic injury | Altered Intercellular Communication | These changes reflect apparently platelet response to the inflammatory process associated with the surgical trauma and confirm the role of NOx as a mediator of inflammation. | 26350744 |
| Inflammation, Diabetes Mellitus, Non-Insulin-Dependent, Obesity | Altered Intercellular Communication | Mechanistic links shared by T2D, AId and life-style factors such as obesity, perhaps through chronic inflammation, may drive autoimmune activation of T2D and many AIds. | 26350756 |
| Inflammation, Nerve Degeneration | Altered Intercellular Communication | This second part shows that immunological phenomena are increasingly more present in the pathogenesis of the disease, and that the interaction between inflammation and neurodegeneration is becoming more apparent. | 26350778 |
| Inflammation, Fibrosis Assessment | Altered Intercellular Communication | Liver biopsy samples from patients were obtained and used to calculate the METAVIR score to define the stage of fibrosis and inflammation grade. | 26350896 |
| Inflammation, Pancreatic carcinoma | Altered Intercellular Communication | Ruxolitinib plus capecitabine was generally well tolerated and may improve survival in patients with metastatic pancreatic cancer and evidence of systemic inflammation. | 26351344 |
| Inflammation, Osteoporosis, Cardiovascular morbidity | Altered Intercellular Communication | Records included demographics, inflammation markers, SpA clinical characteristics, treatment regimes, associated osteoporosis and cardiovascular morbidity. | 26351533 |
| Inflammation, Nephritis, ENL Protein, Neuritis, Osteitis, Skin lesion, Lymphadenitis, Dactylitis, Arthritis, Orchitis | Altered Intercellular Communication | ENL is associated with skin lesions, neuritis, arthritis, dactylitis, eye inflammation, osteitis, orchitis, lymphadenitis and nephritis. | 26351858 |
| Autoimmune Diseases, Communicable Diseases, Neoplasms | Altered Intercellular Communication | Interleukin-17A-producing T cells (IL-17A+ T) (IL-17A+CD4+ Th17, IL-17A+CD8+ Tc17 and IL-17A+ gdT17 cells) and associated cytokines (IL-17A, IL-23 and IL-1b) play crucial roles in inflammation-associated diseases, such as infection, autoimmunity and tumors. | 26352729 |
| Inflammation, Necrosis | Altered Intercellular Communication | No evidence of inflammation, cartilaginous vascularization, or necrosis was identified in any graft. | 26352748 |
| Inflammation, Necrosis | Altered Intercellular Communication | Mild to moderate degrees of chondrocytic dropout in the absence of necrosis and inflammation are probably attributable to the thick and coarsely textured collagen of the fibrous pseudoperichondrial capsule that may impede diffusion of nutrients into the center of the graft. | 26352748 |
| Inflammation, PDR gene, Diabetic Retinopathy, Diabetes Mellitus | Altered Intercellular Communication | Macrophages are involved in low-grade inflammation in diabetes, and play pathogenic roles in proliferative diabetic retinopathy (PDR) by producing proinflammatory cytokines. | 26352837 |
| Airway structure, Pain Distress Question, Laryngeal Edema | Altered Intercellular Communication | Three months after the therapy, the patient had an upper airway inflammation, and then laryngeal edema and pain occurred. | 26355161 |
| Inflammation, Colorectal Neoplasms, Ulcerative Colitis | Altered Intercellular Communication | Patients with ulcerative colitis (UC) are at increased risk of colorectal neoplasia (CRN) presumably because of chronic inflammation. | 26355468 |
| Inflammation, HIV-1 Infection Pathway, Dysbiosis | Altered Intercellular Communication | HIV-1 infection is characterized by altered intestinal barrier, gut microbiota dysbiosis, and systemic inflammation. | 26355675 |
| Inflammation | Altered Intercellular Communication | 10 units increase in PAC-score was associated with 5-8% decrease in the likelihood of higher low-grade inflammation status (i.e. | 26355794 |
| Brain Injuries | Altered Intercellular Communication | [Clinical syndromes of neurotransmitter system dysfunction in severe brain injury]. | 26356514 |
| Deficit | Altered Intercellular Communication | The following clinical syndromes of neurotransmitter system dysfunction were singled out: excess or insufficiency of glutamate, cholinergic deficit, excess or insufficiency of dopamine. | 26356514 |
| Sleep-Disordered Breathing, Inflammation | Altered Intercellular Communication | Sleep Related Breathing Disorders and Inflammation - The Missing Link? | 26356577 |
| Double-Stranded RNA Binding Motif, Inflammation, Obesity, Abnormal breathing | Altered Intercellular Communication | Sleep related breathing disorders (SRBD) are associated with both obesity and systemic inflammation. | 26356577 |
| Double-Stranded RNA Binding Motif, Inflammation, Obesity | Altered Intercellular Communication | While the relationship between obesity and SRBD is established, the causality between inflammation and SRBD remains unclear. | 26356577 |
| ARCN1 gene, Inflammation, Chronic Obstructive Airway Disease | Altered Intercellular Communication | Local and systemic inflammation often present in chronic obstructive pulmonary disease (COPD). | 26356719 |
| ARCN1 gene, Inflammation | Altered Intercellular Communication | In conclusion, circulating CTRP-5 was associated with the severity of airflow obstruction and systemic inflammation in patients with COPD, which suggests that it may be used as a potential novel inflammatory biomarker in COPD. | 26356719 |
| Inflammation, Depression, CTCAE, Psychiatric | Altered Intercellular Communication | Inflammation and depression: combined use of selective serotonin reuptake inhibitors and NSAIDs or paracetamol and psychiatric outcomes. | 26357585 |
| Arterial Stiffness, Inflammation, ETV3 wt Allele, Atherosclerosis | Altered Intercellular Communication | MetS may contribute to the development of atherosclerosis by significantly increasing inflammation levels and arterial stiffness and decreasing circulating EPCs. | 26359174 |
| Sarcopenia | Altered Intercellular Communication | Although the "anti-aging hormone" klotho is associated with sarcopenia in mice, the relationship between klotho and muscle strength in older adults is not well known. | 26359247 |
| Inflammation, Neuromyelitis Optica, Cerebral atrophy | Altered Intercellular Communication | However, severe intrathecal inflammation and massive destruction of neuroglia could cause a secondary progressive clinical course associated with cerebral atrophy in neuromyelitis optica patients. | 26359279 |
| Coughing | Altered Intercellular Communication | A 46-year-old woman presented with cough for over 20 days, unrelieved by anti-inflammation treatment. | 26359558 |
| Inflammation, Retractile Mesenteritis | Altered Intercellular Communication | Biopsy of the mesentery revealed xanthogranulomatous inflammation, consistent with sclerosing mesenteritis. | 26359565 |
| Degenerative polyarthritis, Inflammation, Obesity | Altered Intercellular Communication | These findings highlight an important link between obesity and inflammation in knee osteoarthritis. | 26359653 |
| Inflammatory Bowel Diseases, Gastrointestinal inflammation, Intestinal Diseases | Altered Intercellular Communication | Fecal calprotectin is a noninvasive marker of intestinal inflammation used to distinguish between functional and organic bowel diseases and to evaluate disease activity among patients with Inflammatory Bowel Disease (IBD). | 26359672 |
| Hyperthyroidism, Levator palpebrae superioris structure | Altered Intercellular Communication | A 78-year-old woman with quiescent hyperthyroidism had clinical and radiological evidence of levator palpebrae superioris inflammation without superior rectus involvement. | 26359702 |
| Inflammation, Loss of facial adipose tissue, muscle mass | Altered Intercellular Communication | Anti-Fn14 antibodies prevented tumor-induced inflammation and loss of fat and muscle mass. | 26359988 |
| Inflammatory Bowel Diseases, Inflammation, Increase | Altered Intercellular Communication | The chronic inflammation of the intestinal mucosa, the extra-intestinal manifestations of the disease and the immunosuppressive treatment of inflammatory bowel disease may increase cancer risk. | 26361018 |
| Inflammation | Altered Intercellular Communication | Histopathological analysis of the bioptic pericardium showed a specific chronic inflammation. | 26361701 |
| Inflammation, Traumatic injury | Altered Intercellular Communication | Both blood exposure and trauma are known to induce cell death and inflammation and to enhance proteoglycan release in cartilage. | 26362437 |
| Inflammation, Inflammatory disorder | Altered Intercellular Communication | 'Relapsing-remitting tumefactive inflammation' seems to have the features of a distinct inflammatory CNS disease. | 26362889 |
| Inflammation, Atherosclerosis | Altered Intercellular Communication | In conclusion, o-6-rHDL and o-3-rHDL show different physiological activities in atherosclerosis, inflammation, and cellular senescence. | 26363928 |
| Hyperglycemia, Inflammation | Altered Intercellular Communication | Our results showed the association of hyperglycemia with increased DNA damage and aberrant expression of miRNAs and genes related to several biological processes, such as inflammation, DNA repair, ROS production and antioxidant defense, highlighting the importance of proper glycemic control. | 26364207 |
| AATF wt Allele, Dry Eye Syndromes | Altered Intercellular Communication | Lifitegrast is an integrin antagonist that decreases T-cell-mediated inflammation associated with dry eye disease (DED). | 26365210 |
| Inflammation, Gastrointestinal dysfunction, Dysbiosis, Irritable Bowel Syndrome | Altered Intercellular Communication | Microbial dysbiosis and prolonged immune activation resulting in low-grade inflammation and intestinal barrier dysfunction have been suggested to be underlying causes of post-infectious irritable bowel syndrome (PI-IBS). | 26366730 |
| Epithelial hyperplasia, Pneumonitis | Altered Intercellular Communication | Importantly, pulmonary interstitial inflammation and epithelial hyperplasia that were significantly elevated in immunosuppressed animals were reduced by RI-002 administration. | 26367224 |
| Inflammation, Diabetes Mellitus | Altered Intercellular Communication | Main determinants for APD resistance were a worse control of the diabetes and higher baseline levels of inflammation (mean CRP 26.4 +- 56.0 vs. 9.3 +- 21.0; p < 0.01). | 26367525 |
| Inflammation, Cerebrovascular accident | Altered Intercellular Communication | However, the high frequency of APD resistance and its association with inflammation and stroke severity are confirmed. | 26367525 |
| Communicable Diseases, PLEURAL EFFUSION, BLOODY, Inflammation, Hemoptysis | Altered Intercellular Communication | Intravenous administration of antibiotics and thoracic drainage successfully controlled the infection and inflammation until day 16, when the patient began to exhibit hemoptysis and bloody pleural effusion. | 26369260 |
| Granulomatous inflammation | Altered Intercellular Communication | Biopsy samples obtained from the right upper and left lower paratracheal nodes by mediastinoscopy revealed granulomatous inflammation. | 26369493 |
| Inflammation, ETV3 wt Allele | Altered Intercellular Communication | The association of MetS with elevated IL-1beta level suggests that inflammation plays an important role in its pathogenesis. | 26370103 |
| Inflammation, Diabetes Mellitus, Non-Insulin-Dependent | Altered Intercellular Communication | We assessed associations among glycemic control, inflammation, and CP with cerebral structure on MRI and with cognitive performance in 268 high-risk African Americans with type 2 diabetes. | 26370382 |
| Cessation of life, Cyclophosphamide/Vincristine/Dacarbazine Regimen, Cardiovascular Diseases | Altered Intercellular Communication | The predictive value of HDL particle subclasses and inflammatory markers was studied for noncardiovascular, noncancer chronic inflammation-related death and hospitalization, and for incident cardiovascular disease (CVD). | 26370448 |
| Cessation of life | Altered Intercellular Communication | Small- plus medium-diameter HDL particles were inversely associated with diagnostic code-based noncardiovascular, noncancer chronic inflammation-related death and hospitalization (n=1054) independent of covariates: relative risk per SD 0.85 (95% CI: 0.79 to 0.91, P<0.0001). | 26370448 |
| Cessation of life, Coronary heart disease | Altered Intercellular Communication | Small- plus medium-diameter HDL particles are an independent predictor for noncardiovascular, noncancer chronic inflammation-related death and hospitalization and for coronary heart disease events in subjects initially free of overt CVD. | 26370448 |
| Inflammation | Altered Intercellular Communication | Corticosteroids may be able to successfully treat such inflammation or disruption of the blood ocular barrier. | 26370869 |
| Diego blood group system, Colitis | Altered Intercellular Communication | The hypothesis is that DI constituted a source of colonic inflammation, sending out bacterial antigenic stimuli that resulted in PG through deposition of circulating immune complexes. | 26372545 |
| Airway structure | Altered Intercellular Communication | Serum chitinases may be novel biomarkers of airway inflammation and remodeling, but less is known about factors regulating their levels. | 26372680 |
| Granulomatosis, Orofacial, Inflammation, Pathology | Altered Intercellular Communication | Orofacial granulomatosis represents a group of pathologies characterized by a granulomatous inflammation of the face and the oral mucosa. | 26372981 |
| Inflammation, Pathology | Altered Intercellular Communication | Since the macrocheilitis resulting from an inflammation could be associated to different pathologies, an accurate diagnosis has to be established. | 26372981 |
| Refractory anemias, Inflammation | Altered Intercellular Communication | Active RA (28-joint Disease Activity Score >= 2.6: OR 3.4, 95% CI 1.3-9.8) was an independent risk factor of HF, as well as systemic inflammation (erythrocyte sedimentation rate > 16 mm/h: OR 5.4, 95% CI 2.1-16; C-reactive protein > 10 mg/l: OR 2.6, 95% CI 0.8-8.0) and RA duration > 10 years (OR 2.6, 95% CI 1.2-5.8). | 26373561 |
| Refractory anemias, Inflammation | Altered Intercellular Communication | These results suggest that calprotectin might be superior to CRP for monitoring ultrasound-determined synovial inflammation in RA patients. | 26373925 |
| vascular inflammations | Altered Intercellular Communication | ERN/LRP reduces LDL-associated mediators of vascular inflammation, but has varied effects on HDL functionality and LDL quality, which may counter its HDL-C-raising effect. | 26374297 |
| Airway structure | Altered Intercellular Communication | She had additional airway inflammation leading to a TEF at the site of esophageal ulceration, requiring tracheostomy. | 26374667 |
| Inflammation, IgG4-Related Sclerosing Disease | Altered Intercellular Communication | Role of interleukin-32 in the mechanism of chronic inflammation in IgG4-related disease and as a predictive biomarker for drug-free remission. | 26375328 |
| Inflammation | Altered Intercellular Communication | In immunoglobulin (Ig) G4-related disease (IgG4-RD), the mechanism of chronic inflammation and predictive factors for drug-free remission is still unclear. | 26375328 |
| Inflammation | Altered Intercellular Communication | A characteristic pattern of symmetrical, extracapsular inflammation, adjacent to greater trochanter, acetabulum, ischial tuberosity and/or symphysis pubis, was observed in 14/22 of the PMR cases. | 26376658 |
| Inflammation | Altered Intercellular Communication | A subset of patients with rheumatologist-diagnosed PMR had a characteristic, extracapsular pattern of MRI inflammation, associated with elevated IL-6/CRP and with complete patient-reported glucocorticoid responsiveness. | 26376658 |
| Inflammation, Primary malignant neoplasm | Altered Intercellular Communication | Moreover, a LC-MS/MS approach revealed 49 serum proteins with different abundances between healthy donors and cancer patients (predominantly proteins associated with inflammation and acute phase response). | 26376850 |
| Inflammation, Periodontitis, Sleeplessness | Altered Intercellular Communication | Periodontitis causes chronic discomfort and inflammation, and little is known about its impact on insomnia. | 26377351 |
| Autoimmune Diseases, Inflammation | Altered Intercellular Communication | Regulatory B cells (Bregs) play a critical role in inflammation and autoimmune disease. | 26378021 |
| Inflammation, Social security number, Leukoplakia | Altered Intercellular Communication | Signs more frequent in OSSN included feeder vessels (odds ratio [OR], 5.8 [95% CI, 3.2-10.5]), moderate inflammation (OR, 3.5 [95% CI, 1.8-6.8]), corneal involvement (OR, 2.7 [95% CI, 1.8-4.0]), leukoplakia (OR, 2.6 [95% CI, 1.7-3.9]), papilliform surface (OR, 2.1 [95% CI, 1.3-3.5]), pigmentation (OR, 1.5 [95% CI, 1.0-2.2]), temporal location (OR, 2.0 [95% CI, 1.2-3.2]), circumlimbal location (6.7% vs 0.3%; P < .001), severe inflammation (6.7% vs 0.3%; P < .001), and larger mean (SD) diameter (6.8 [3.2] vs 4.8 [2.8] mm; P < .001). | 26378395 |
| Inflammation | Altered Intercellular Communication | As exercise is associated with reduced systemic inflammation, we hypothesized that suppression of the pro-inflammatory transcription factor nuclear factor k B (NFkB) may mediate this process. | 26378681 |
| IgG4-Related Sclerosing Disease, Scleritis | Altered Intercellular Communication | Recent investigation suggests that many cases of sclerosing orbital inflammation are a manifestation of IgG4-related disease; however, most patients reported have been Asian, and it is not clear whether the results of studies from the Far East can be reliably extrapolated to draw conclusions about Western patients. | 26379149 |
| Soft tissues of orbit, Chronic dacryoadenitis, Orbital Pseudotumor, Scleritis | Altered Intercellular Communication | We evaluated 38 cases previously diagnosed as orbital inflammatory pseudotumor or chronic dacryoadenitis to determine whether our cases fulfill the criteria for IgG4-RD (IgG4-related dacryoadenitis when involving the lacrimal gland, and IgG4-related sclerosing orbital inflammation when involving orbital soft tissue). | 26379149 |
| Dacryoadenitis, Orbital Pseudotumor | Altered Intercellular Communication | Fifteen patients had IgG4-related dacryoadenitis or orbital inflammation. | 26379149 |
| Inflammation, Granulomatosis, Fibrosis Assessment, Systemic Vasculitis, Disease | Altered Intercellular Communication | These patients had a variety of diseases, including granulomatosis with polyangiitis (3 cases), Rosai-Dorfman disease (1 case), nonspecific chronic inflammation and fibrosis involving lacrimal gland or soft tissue (12 cases), and others. | 26379149 |
| Inflammation, Periostitis, Vasculitis, CTCAE, Myositis, CTCAE 5.0 | Altered Intercellular Communication | Myositis, periostitis, (peri-) vasculitis and axillary inflammation were confirmed by magnetic resonance imaging. | 26379162 |
| Inflammation, Pneumonitis | Altered Intercellular Communication | However, MAp2009-induced lung inflammation was sustained until the end of the study (day 14), while there was no sign of inflammation in the PR8-infected group by day 10. | 26381265 |
| Inflammation, Tumor necrosis | Altered Intercellular Communication | Additionally, inflammation is associated with M1-polarizated macrophages, which secrete cytokines such as tumor necrosis factor-a, interleukin-1, and interleukin-12, and present antigens through phagocytosis. | 26382585 |
| Inflammation, Endothelial dysfunction | Altered Intercellular Communication | The glycoprotein YKL-40 is a new marker of early inflammation and endothelial dysfunction. | 26382922 |
| Stomach Carcinoma | Altered Intercellular Communication | It is involved in the regulation of inflammation-mediated carcinogenesis in human organs, including gastric cancer. | 26383107 |
| Inflammation | Altered Intercellular Communication | We diagnosed a broad, multiloculated mesenteric and retroperitoneal cyst, associated with intensive inflammation, in a 4-year-old girl. | 26384119 |
| Inflammation, Muscular Atrophy, Bipolar Disorder | Altered Intercellular Communication | Inflammation related to depressive symptoms may also contribute to muscle atrophy. | 26384322 |
| Inflammation, Breast Carcinoma | Altered Intercellular Communication | Links between inflammation, amygdala reactivity, and social support in breast cancer survivors. | 26384778 |
| Inflammation, Primary malignant neoplasm | Altered Intercellular Communication | To date, however, little is known about the upstream neural processes that may link psychosocial stressors and inflammation in cancer patients and survivors. | 26384778 |
| Inflammation, Breast Carcinoma | Altered Intercellular Communication | These data suggest the possibility of a stronger "neural-immune pipeline" among breast cancer survivors, such that peripheral inflammation is more strongly associated with neural activity in threat-related brain regions. | 26384778 |
| Inflammation, Cardiac Death, Atherosclerosis | Altered Intercellular Communication | A case of sudden cardiac death due to eosinophilic coronary periarteritis: possible significance of coexisting atherosclerosis and eosinophilic inflammation of the esophagus. | 26385173 |
| Inflammation, Atherosclerosis | Altered Intercellular Communication | A short segment of the left anterior descending artery had ECPA with dense eosinophilic inflammation of the adventitia and mild atherosclerosis. | 26385173 |
| Inflammation | Altered Intercellular Communication | In addition, eosinophilic inflammation of the esophagus without mucosal involvement was present. | 26385173 |
| Inflammation | Altered Intercellular Communication | The eosinophilic inflammation of the coronary artery and esophagus was accompanied by an increased number of mast cells. | 26385173 |
| Inflammation, Atherosclerosis | Altered Intercellular Communication | This case suggests that ECPA and atherosclerosis may act synergistically by induction of inflammation and vasa vasorum neovascularization. | 26385173 |
| Inflammation, Diabetes Mellitus | Altered Intercellular Communication | As low-grade inflammation predicts a poor outcome, the present study explored the potential associations between Type A and plasma levels of C-reactive protein (CRP) in diabetes. | 26385557 |
| Inflammation, Diabetes Mellitus | Altered Intercellular Communication | This lower level of inflammation might explain the better clinical outcomes associated with Type A personality in patients with diabetes. | 26385557 |
| Inflammation, Chronic Obstructive Airway Disease | Altered Intercellular Communication | Klotho Reduction in Alveolar Macrophages Contributes to Cigarette Smoke Extract-induced Inflammation in Chronic Obstructive Pulmonary Disease. | 26385922 |
| ARCN1 gene, Respiratory physiology, Abnormal inflammatory response, Chronic Obstructive Airway Disease | Altered Intercellular Communication | Abnormal inflammation and accelerated decline in lung function occur in patients with chronic obstructive pulmonary disease (COPD). | 26385922 |
| ARCN1 gene, Inflammation | Altered Intercellular Communication | Our findings suggest that Klotho plays a role in sustained inflammation of the lungs, which in turn may have therapeutic implications in COPD. | 26385922 |
| Inflammation, Frailty, HIV Infections, Aspects of mortality statistics | Altered Intercellular Communication | Frailty, Inflammation, and Mortality Among Persons Aging With HIV Infection and Injection Drug Use. | 26386010 |
| Inflammation | Altered Intercellular Communication | Serum markers of inflammation increase with age and have been strongly associated with adverse clinical outcomes among both HIV-infected and uninfected adults. | 26386010 |
| Inflammation | Altered Intercellular Communication | Cytokines play important roles in the inflammation pathways. | 26386715 |
| Refractory anemias, Inflammation, Pain Distress Question | Altered Intercellular Communication | PA can improve physical function in RA, decrease chronic inflammation and reduce pain, without adversely affecting disease activity. | 26386844 |
| Inflammation, Edema, Myositis, CTCAE 5.0, Neoplasms | Altered Intercellular Communication | Knowledge of the imaging features of intramuscular migration of hydroxyapatite deposits is important in order to avoid the erroneous diagnosis of other causes of muscle edema and inflammation such as myotendinous injury, myositis, subacute denervation, and neoplasm. | 26386846 |
| Sepsis, Inflammation, Hypoxia, Septic Shock | Altered Intercellular Communication | Our data suggest a possible role for CXCL12 as a prognostic marker in severe sepsis/septic shock and give background evidence for larger trials to evaluate the pathophysiologic and clinical role of CXCL12 in sepsis, with respect to other markers of inflammation and hypoxia. | 26387470 |
| Inflammation, Central pain | Altered Intercellular Communication | Since the choroid plexus can mediate interaction between peripheral and brain inflammation, our findings pinpoint the choroid plexus as an important target for future research of central pain mechanisms. | 26388497 |
| Inflammation, Coronary Arteriosclerosis | Altered Intercellular Communication | Coronary atherosclerosis in the young commonly shows an eccentric distribution with associated inflammation. | 26390307 |
| Inflammation, Pain Distress Question | Altered Intercellular Communication | The role of transient receptor potential vanilloid-1 (TRPV1) in the initiation of neurogenic inflammation and transduction of pain is well established. | 26390894 |
| Degenerative polyarthritis, Inflammation | Altered Intercellular Communication | Betulinic acid inhibits IL-1b-induced inflammation by activating PPAR-g in human osteoarthritis chondrocytes. | 26391061 |
| Degenerative polyarthritis, Inflammation | Altered Intercellular Communication | In conclusion, these results suggested that BA inhibited IL-1b-induced inflammation in osteoarthritis chondrocytes by activating PPAR-g. | 26391061 |
| Synovitis, Inflammation, Hoarseness, Cartilage injury | Altered Intercellular Communication | However, some patients with hoarseness due to mucosal inflammation of the larynx might have accompanying synovitis and subsequent cartilage injury in the CA joint. | 26391093 |
| Inflammation, Hypertension, CTCAE | Altered Intercellular Communication | Several cross-sectional, but few prospective, studies suggest that inflammation may be involved in the development of hypertension. | 26391130 |
| Inflammation, Atherosclerosis | Altered Intercellular Communication | High-sensitivity C-reactive protein (hsCRP), a marker of systemic inflammation, may promote atherosclerosis, particularly among adults with elevated blood pressure; however, data are sparse. | 26391131 |
| Inflammation, Neoplasms | Altered Intercellular Communication | Besides blocking inflammation, SOCS1 tumour suppressor activity involves Met receptor inhibition and enhancement of p53 tumour suppressor activity. | 26391193 |
| Refractory anemias, Rheumatoid Arthritis, destruction joint, Inflammation | Altered Intercellular Communication | Because MFG-E8 also controls bone metabolism, we investigated its role in rheumatoid arthritis (RA), focusing on inflammation and joint destruction. | 26391522 |
| Refractory anemias, Inflammation | Altered Intercellular Communication | The regulation of MFG-E8 by inflammation was assessed in vitro using osteoblasts, in arthritic mice and in patients with RA. | 26391522 |
| Inflammation, Liver carcinoma, Intrahepatic Cholangiocarcinoma, Malignant neoplasm of liver, FAM126A gene | Altered Intercellular Communication | Chronic inflammation plays a pivotal role in the pathogenesis of hepatocellular carcinoma (HCC) and intrahepatic cholangiocarcinoma (ICC), the two most common types of liver cancer. | 26391917 |
| Autoimmune Diseases, Inflammation, Primary malignant neoplasm | Altered Intercellular Communication | Th17 cells, a subset of IL-17-producing T cells distinct from Th1 or Th2 cells, have been described as key players in inflammation and autoimmune diseases as well as cancer development. | 26392085 |
| Inflammation, Immune System Diseases | Altered Intercellular Communication | Oxidative stress and chronic low-grade inflammation in the lungs are associated with aging and may contribute to age-related immune dysfunction. | 26392224 |
| Inflammation | Altered Intercellular Communication | To maintain lung homeostasis, chronic inflammation is countered by enhanced expression of proresolving/antiinflammatory factors. | 26392224 |
| Inflammation, Depression, CTCAE | Altered Intercellular Communication | Inflammation, Depression, and Slow Gait: A High Mortality Phenotype in Later Life. | 26392405 |
| Inflammation, Depression, CTCAE | Altered Intercellular Communication | Inflammation, slow gait, and depression individually are associated with mortality, yet little is known about the trajectories of these measures, their interrelationships, or their collective impact on mortality. | 26392405 |
| Inflammation, Impaired health, Depression, CTCAE | Altered Intercellular Communication | For each outcome, low-probability (n inflammation = 1,656, n slow gait = 1,471, n depression = 1,458), increasing-probability (n inflammation = 847, n slow gait = 880, n depression = 1,062), and consistently high-probability (n inflammation = 572, n slow gait = 724, n depression = 555) trajectories were identified, with 22% of all participants classified as having increasing or consistently high-probability trajectories on inflammation, slow gait, and depression (meaning probability of impairment on each outcome increased from low to moderate/high or remained high over 10 years). | 26392405 |
| Inflammation, Depression, CTCAE | Altered Intercellular Communication | Trajectories of slow gait were associated with inflammation (r = .40, p < .001) and depression (r = .49, p < .001). | 26392405 |
| Inflammation, Depression, CTCAE | Altered Intercellular Communication | Although worsening trajectories of inflammation were independently associated with mortality (p < .001), the association between worsening trajectories of slow gait and mortality was only present in participants with worsening depression trajectories (p < .01). | 26392405 |
| Inflammation, Depression, CTCAE | Altered Intercellular Communication | Participants with increasing/consistently high trajectories of depression and consistently high trajectories of inflammation and slow gait (n = 247) have an adjusted-morality rate of 85.2%, greater than all other classification permutations. | 26392405 |
| Inflammation, Depression, CTCAE | Altered Intercellular Communication | Comprehensive assessment of older adults is warranted for the development of treatment strategies targeting a high-mortality risk phenotype consisting of inflammation, depression, and slow gait speed. | 26392405 |
| Inflammation, Chronic Obstructive Airway Disease, Impairment of balance | Altered Intercellular Communication | Balance impairment and systemic inflammation in chronic obstructive pulmonary disease. | 26392759 |
| ARCN1 gene, Inflammation, Chronic Obstructive Airway Disease, Impairment of balance | Altered Intercellular Communication | Chronic obstructive pulmonary disease (COPD), especially in severe forms, is commonly associated with systemic inflammation and balance impairment. | 26392759 |
| ARCN1 gene, Inflammation, Lower Extremity Paresis, Impairment of balance | Altered Intercellular Communication | According to this study, COPD in advanced and acute stages is associated with an increased history of falls, systemic inflammation, balance impairment, and lower extremity muscle weakness. | 26392759 |
| Data types - Address | Altered Intercellular Communication | Inflammation would induce autophagy in the PBMCs of AD patients while an anti-inflammatory environment could inhibit their autophagic response. | 26393801 |
| Inflammation, GTF2A1L wt Allele, Bacterial Infections | Altered Intercellular Communication | While PCT appears to be a robust assay for detecting bacterial infection in the general population, there was poor discrimination between ALF patients with or without bacterial infection presumably because of the massive inflammation observed. | 26393924 |
| Inflammation, GTF2A1L wt Allele, Necrosis | Altered Intercellular Communication | Severe hepatocyte necrosis with inflammation results in elevated PCT levels, rendering this biomarker unreliable in the ALF setting. | 26393924 |
| Inflammation, Actual blood loss, Anemia, Kidney Failure | Altered Intercellular Communication | Several mechanisms have been implicated in the etiology of anemia in this setting, including inflammation, blood loss, and the presence of comorbidities such as renal failure. | 26394493 |
| Inflammation, Erythema, Fissure | Altered Intercellular Communication | We developed an Isotretinoin Cheilitis Grading Scale (ICGS) incorporating the following four characteristics: erythema, scale/crust, fissures and inflammation of the commissures. | 26395167 |
| Inflammation, Chronic Kidney Diseases | Altered Intercellular Communication | It is more predominant in patients with Chronic Kidney Disease in comparison to healthy subjects, which can also be diagnosed in non-elderly individuals and be associated with innumerous causes such as muscle strength, body composition and inflammation. | 26395776 |
| Inflammation, Kidney Failure, Acute | Altered Intercellular Communication | Processes unrelated to kidney function such as acute inflammation have a significant effect on post-CPB changes in these biomarkers, and may result in significant increases in serum cystatin C that could erroneously be interpreted as AKI. | 26396066 |
| Inflammation, Observation Method - Coagulation | Altered Intercellular Communication | While sequestration of parasitized erythrocytes is thought to be critical, the roles of inflammation and coagulation are controversial. | 26396242 |
| Inflammation, HIV Infections, Certified Midwife | Altered Intercellular Communication | Because HIV infection is associated with dysregulated inflammation and platelet activation, we performed immunohistochemistry analysis for monocytes, platelets, and neutrophils in brain tissue from HIV(+) and HIV-uninfected children with fatal CM. | 26396242 |
| Inflammation, Observation Method - Coagulation, Certified Midwife | Altered Intercellular Communication | Brain histopathology supports the hypotheses that inflammation and coagulation contribute to the pathogenesis of pediatric CM and that immune dysregulation in HIV(+) children exacerbates the pathological features associated with CM. | 26396242 |
| Inflammation, Malaria, Observation Method - Coagulation, Certified Midwife | Altered Intercellular Communication | Our findings raise the possibility that HIV(+) children at risk for malaria may benefit from targeted malaria prophylaxis and that adjunctive treatments targeting inflammation and/or coagulation may improve CM outcomes. | 26396242 |
| Hypercholesterolemia, Inflammation | Altered Intercellular Communication | We aimed to elucidate the underlying mechanism of NR4A1 expression in monocytes during hypercholesterolaemia, and reveal the potential role of NR4A1 in hypercholesterolaemia-induced circulating inflammation. | 26396259 |
| Hypercholesterolemia, Inflammation | Altered Intercellular Communication | Thus we conclude that histone acetylation contributes to the regulation of NR4A1 expression in hypercholesterolaemia, and that NR4A1 expression reduces hypercholesterolaemia-induced inflammation. | 26396259 |
| Inflammation, Metabolic Diseases | Altered Intercellular Communication | Our results demonstrate a higher circulating ANGPTL2 level in patients with HF, and the upregulating ANGPTL2 levels might be associated with metabolic derangements and inflammation. | 26397985 |
| Granulomatous inflammation, Crohn Disease | Altered Intercellular Communication | Granulomatous inflammation consistent with Crohn's disease was found on histopathological examination. | 26398073 |
| Inflammation, Chronic Kidney Diseases | Altered Intercellular Communication | Inflammation, Endothelial Dysfunction and Increased Left Ventricular Mass in Chronic Kidney Disease (CKD) Patients: A Longitudinal Study. | 26398099 |
| Inflammation, Endothelial dysfunction, Chronic Kidney Diseases | Altered Intercellular Communication | The results suggest that in predialysis CKD patients, inflammation as well as endothelial dysfunction may play an important role towards the increase in LVMI. | 26398099 |
| Inflammation, Coronary Artery Disease, Bipolar Disorder | Altered Intercellular Communication | It is well known that inflammation contributes to the development of coronary artery disease (CAD) and depressive symptoms. | 26398164 |
| Inflammation, Depression, CTCAE, Bipolar Disorder | Altered Intercellular Communication | We hypothesized that inflammation contributes to depression in patients with CAD and statin function as an anti-inflammation therapy for those depressive patients. | 26398164 |
| Inflammation, Depression, CTCAE | Altered Intercellular Communication | It suggested that depression in patients with CAD is associated with inflammation. | 26398164 |
| Depression, CTCAE | Altered Intercellular Communication | Statin may function as an anti-inflammation therapy for depression in patients with CAD by downregulation of IL-1b. | 26398164 |
| Inflammation, Coronary heart disease, Atrial Fibrillation by ECG Finding, Cerebrovascular accident | Altered Intercellular Communication | Inflammation and hemostasis in atrial fibrillation and coronary heart disease: The REasons for Geographic And Racial Differences in Stroke study. | 26398291 |
| Inflammation, Choline Dehydrogenase, Mitochondrial | Altered Intercellular Communication | To determine if alterations in hemostasis or inflammation explain the association between AF and CHD. | 26398291 |
| Inflammation, Atrial Fibrillation, Choline Dehydrogenase, Mitochondrial | Altered Intercellular Communication | Using a case-cohort approach, Cox models examined whether inflammation or hemostasis biomarkers explained the association between AF and CHD. | 26398291 |
| Inflammation, Pouchitis, Crohn Disease | Altered Intercellular Communication | Sixty-one percent of respondents had pouch inflammation (pouchitis, N = 35; cuffitis, N = 14; and Crohn's disease of the pouch, N = 35), 20% had IPS (N = 27) and 19% (N = 26) had asymptomatic normal pouches. | 26398708 |
| Inflammation, Malnutrition, Crohn Disease | Altered Intercellular Communication | Systemic inflammation and nutritional deficiencies are characteristics of Crohn's disease (CD) and have been suggested to influence cognitive performance. | 26398711 |
| Airway structure, Asthma | Altered Intercellular Communication | These results suggest that airway inflammation aggravated by ADS exposure may induce a decrease in pulmonary function in some adult patients with asthma. | 26399354 |
| Inflammation | Altered Intercellular Communication | Increased serum levels of CRP and serum and aqueous levels of TNF-a in DME suggest that inflammation is involved in the pathogenesis of DME. | 26400051 |
| Neurodegenerative Disorders, Primary malignant neoplasm, Inflammation, Autoimmune Diseases, Diabetes Mellitus | Altered Intercellular Communication | Chronic inflammation negatively impacts all physiological functions, causing an array of degenerative conditions including diabetes; cancer; cardiovascular, osteo-articular, and neurodegenerative diseases; autoimmunity disorders; and aging. | 26400428 |
| Inflammation | Altered Intercellular Communication | We attempted relief of symptoms by reducing scalp inflammation and eliminating hair follicles through radiation. | 26400479 |
| Inflammation, Diabetes Mellitus | Altered Intercellular Communication | The pro-inflammatory cytokine IL-17, which is produced by T-helper 17 (Th17) cells, has been reported to be involved in the glucose metabolism and pathogenesis of diabetes via the induction of low-grade inflammation. | 26400516 |
| Inflammation, Squamous cell carcinoma of esophagus | Altered Intercellular Communication | Diet and inflammation have been suggested to be important risk factors for esophageal squamous cell carcinoma (ESCC). | 26400625 |
| Inflammation | Altered Intercellular Communication | Similarly, vocal fold injection of silicone elastomer (Silastic) can result not only in a false-positive FDG uptake on PET/CT, but also in chronic inflammation. | 26401671 |
| Inflammation, "Alzheimers Disease", Data types - Address | Altered Intercellular Communication | Peripheral inflammation has been suggested to influence the development of Alzheimer's disease (AD). | 26402013 |
| Inflammation, atherosclerotic | Altered Intercellular Communication | Based on our in vivo and in vitro findings we suggest that NAMPT could contribute to systemic and plaque inflammation in atherosclerotic disorders at least partly through effect on macrophages. | 26402139 |
| Inflammation, Data types - Address | Altered Intercellular Communication | Inflammation is involved in AD and it is suggested that anti-inflammatory interleukin-10 (IL-10) may partly antagonize these processes. | 26402514 |
| Inflammation, Vasogenic Edema | Altered Intercellular Communication | Neuroradiological evidence of cerebral inflammation (vasogenic edema) and sulcal superficial siderosis or multiple areas of cortical/subcortical microhemorrhages (MHs) were evaluated based upon fluid-attenuated inversion recovery and T2 *-weighted gradient echo or susceptibility weighted imaging, respectively. | 26402633 |
| HIV Infections | Altered Intercellular Communication | We thus identified adipose tissue as a crucial cofactor in both viral persistence and chronic immune activation/inflammation during HIV infection. | 26402858 |
| Inflammation | Altered Intercellular Communication | These observations open up new therapeutic strategies for limiting the size of the viral reservoir and decreasing low-grade chronic inflammation via the modulation of adipose tissue-related pathways. | 26402858 |
| Inflammation | Altered Intercellular Communication | Collectively, results indicated that elevated serum FLCs reflects increased B cell activity in relation to inflammation. | 26402865 |
| Inflammation, Hematoma, Cerebral Hemorrhage | Altered Intercellular Communication | CD163/Hemoglobin Oxygenase-1 Pathway Regulates Inflammation in Hematoma Surrounding Tissues after Intracerebral Hemorrhage. | 26403367 |
| Inflammation, Hematoma, Hemorrhage | Altered Intercellular Communication | The highest inflammation level in tissues surrounding ICH hematomas occurred 2-3 days after bleeding onset, but was accompanied by an anti-inflammatory factor IL-10 expression enhancement. | 26403367 |
| Inflammation, Glucose Intolerance (disease), Obesity, Hyperlipidemia | Altered Intercellular Communication | Epidemiological evidence indicates an inverse association between nut consumption and obesity, inflammation, hyperlipidaemia and glucose intolerance. | 26404365 |
| Refractory anemias, Rheumatoid Arthritis, Inflammation | Altered Intercellular Communication | Rheumatoid arthritis (RA) is characterized by chronic synovial inflammation due to unknown causes. | 26404390 |
| Inflammation, Traumatic injury, Pruritus, Pain Distress Question | Altered Intercellular Communication | Keloids may follow local skin trauma or inflammation leading to pruritus, pain, restriction of movement or cosmetic disfigurement. | 26404425 |
| Inflammation | Altered Intercellular Communication | The DNA damage response induces inflammation and senescence by inhibiting autophagy of GATA4. | 26404840 |
| Inflammation | Altered Intercellular Communication | GATA4 accumulates in multiple tissues, including the aging brain, and could contribute to aging and its associated inflammation. | 26404840 |
| Upper Respiratory Infections, Congenital Abnormality, Communicable Diseases, Respiration Disorders, Lung diseases | Altered Intercellular Communication | We examined associations between FOT outcomes and the presence and progression of respiratory inflammation, infection and structural lung disease.Children with CF who had pronounced respiratory disease, including free neutrophil elastase activity, infection with pro-inflammatory pathogens and structural lung abnormalities had similar FOT outcomes to those children without detectable lung disease. | 26405283 |
| Inflammation, Chronic Kidney Diseases, Glomerulonephritis, Toxic nephropathy | Altered Intercellular Communication | Their increased risk of CKD may be attributed to glomerulonephritis, chronic inflammation, comorbidities, and renal toxicity of antirheumatic drugs. | 26406879 |
| Inflammation, Uveitis | Altered Intercellular Communication | Uveitis was classified based on the anatomic location of inflammation (IUSG classification). | 26408195 |
| Inflammation, Panuveitis, Scleritis, Uveitis, Retinal Vasculitis, Traumatic injury, Anterior uveitis, Endophthalmitis, CTCAE | Altered Intercellular Communication | Out of 980 patients with uveitis, 413 (42.14 %) patients had anterior uveitis, 131 (13.36 %) had intermediate uveitis, 165 (16.83 %) had posterior uveitis, 91 (9.2 %) had panuveitis, 47 (4.7 %) had retinal vasculitis, 22 (2.24 %) had scleritis, 17 (1.7 %) had masquerade syndromes, 8 (0.8 %) had keratouveitis, 22 (2.24 %) had sclerokeratouveitis, 19 (1.9 %) had endophthalmitis and 45 (4.5 %) had other causes of inflammation including trauma and intraocular surgery. | 26408195 |
| Inflammation | Altered Intercellular Communication | Receptor binding leads to activation of the vascular endothelium and increased inflammation in the vessel wall. | 26408307 |
| Arterial Stiffness, Inflammation, Choroidal and Ciliary Body Melanoma pT1d TNM Finding v8 | Altered Intercellular Communication | The results show a possible protective effect of high levels of sRAGE at baseline against inflammation 5 years later, but not on arterial stiffness or wall thickness, in this cohort of adolescents and young adults with T1D. | 26408307 |
| Inflammation, Chronic Obstructive Airway Disease | Altered Intercellular Communication | Nerve growth factor and its receptors, TrkA and p75NTR, are involved in inflammation and airways diseases, but their role in chronic obstructive pulmonary disease is still unclear and not well investigated. | 26408608 |
| Inflammation, Anemia | Altered Intercellular Communication | Fifty-four could not be classified: 12 were anaemic with findings, other than normal CRP values, indistinguishable from those with anaemia of inflammation and 42 were non-anaemic with reduced MCH values. | 26408651 |
| Dermatitis, Atopic, Data types - Address | Altered Intercellular Communication | Atopic dermatitis (AD) is defined as a chronic, highly pruritic inflammatory condition of skin. | 26408885 |
| Trismus, Inflammation | Altered Intercellular Communication | Clinical examination revealed palpable crepitus at the level of the head, neck and pre-sternal region but no inflammation, trismus or fluid collection was detected. | 26409565 |
| Inflammation, Angioedemas, Hereditary | Altered Intercellular Communication | C1 inhibitors are approved for hereditary angioedema but may show promise in alleviating inflammation associated with ACE inhibitor angioedema. | 26409672 |
| Degenerative polyarthritis, Inflammation | Altered Intercellular Communication | FLS via eotaxin-1 and its receptor CCR3 plays an important role in the pathogenesis of OA, which strengthen the concept that OA is likely an inflammation related disease. | 26409848 |
| Inflammation, Atrial Fibrillation by ECG Finding | Altered Intercellular Communication | Increasing evidence suggests that inflammation plays an important role in initiation and maintaining of atrial fibrillation (AF). | 26411136 |
| Atrial Fibrillation, Inflammation, Atrial Fibrillation by ECG Finding | Altered Intercellular Communication | A strong interdependence is known between atrial fibrillation (AF), inflammation and thrombogenesis. | 26411420 |
| Inflammation, Fatty degeneration, Cachexia, Pancreatic carcinoma | Altered Intercellular Communication | Patients with pancreatic cancer have a poor prognosis, are often cachectic, and frequently demonstrate features of systemic inflammation, which may contribute to the phenomenon of myosteatosis. | 26411749 |
| Atrial Fibrillation by ECG Finding | Altered Intercellular Communication | Atrial fibrillation is associated with hematopoietic tissue activation and arterial inflammation. | 26411879 |
| Inflammation, Atrial Fibrillation, Atrial Fibrillation by ECG Finding | Altered Intercellular Communication | Inflammation is associated with the development of atrial fibrillation (AF). | 26411879 |
| Inflammation, Arteritis | Altered Intercellular Communication | Activity in hematopoietic tissues, which produce inflammatory leukocytes, is closely related to systemic inflammation, arterial inflammation and cardiovascular events, but its relationship to AF is unknown. | 26411879 |
| vascular inflammations | Altered Intercellular Communication | Using 18F-fluorodeoxyglucose (FDG) positron emission tomography (PET) imaging, we examined the relationships between AF, splenic metabolic activity and vascular inflammation. | 26411879 |
| Vasculitis | Altered Intercellular Communication | Splenic metabolic activity and vascular aortic inflammation were measured by the mean FDG maximum standard uptake values (SUV Max) by PET. | 26411879 |
| Inflammation | Altered Intercellular Communication | Aortic inflammation was also higher in AF participants [2.22 (SD 0.44) vs. 1.91 (SD 0.44), p = 0.004], and remained significant on multivariable analysis. | 26411879 |
| Inflammation | Altered Intercellular Communication | Aortic inflammation and splenic activity were highly correlated (Pearson R = 0.61, p < 0.001). | 26411879 |
| Atrial Fibrillation by ECG Finding | Altered Intercellular Communication | Atrial fibrillation is associated with higher hematopoietic tissue activation and arterial inflammation. | 26411879 |
| Inflammation, Endothelial dysfunction, Vascular Alterations | Altered Intercellular Communication | They are caused by cardiovascular risk factors including low-grade inflammation process, endothelial dysfunction, oxidative stress, and hemodynamic and vascular alterations. | 26412411 |
| Inflammation, Nasal Polyps, Sinusitis | Altered Intercellular Communication | To analyze the differential expression of miRNAs in chronic sinusitis, with or without nasal polyps (nasal polyps, NP), seven miRNAs (miR- 181b, miR-26b, miR-155, miR-146a, miR-125b, miR-124 and miR-92a) that are associated with inflammation were selected to be quantifying by RT-qPCR in 40 clinical samples and 5 controls. | 26413631 |
| Inflammation, Craniosynostosis | Altered Intercellular Communication | The RT-qPCR results indicate that the miRNAs were differentially expressed in CRS patients and various inflammation severities could lead to this difference. | 26413631 |
| Inflammation | Altered Intercellular Communication | Chronic inflammation and risk of colorectal and other obesity-related cancers: The health, aging and body composition study. | 26413860 |
| Inflammation, Colorectal Carcinoma | Altered Intercellular Communication | Evidence of the association between chronic inflammation and the risk of colorectal cancer (CRC) and other obesity-related cancers (OBRC) remains inconsistent, possibly due to a paucity of studies examining repeated measures of inflammation. | 26413860 |
| Inflammation, Atherosclerosis | Altered Intercellular Communication | The relationship between inflammation and neoangiogenesis of epicardial adipose tissue and coronary atherosclerosis based on computed tomography analysis. | 26414208 |
| Inflammation, Atherosclerosis | Altered Intercellular Communication | We evaluated the relationship between EAT pathology, represented by inflammation and neoangiogenesis, and coronary atherosclerosis on computed tomography (CT) images. | 26414208 |
| Inflammation, Calcification of coronary artery, Coronary Arteriosclerosis, Eating | Altered Intercellular Communication | Inflammation and neoangiogenesis in EAT independently correlate with moderate coronary calcification and presence of NCP, suggesting that these two factors may have a role in promoting coronary atherosclerosis. | 26414208 |
| Degenerative polyarthritis, Inflammation, Superficial ulcer | Altered Intercellular Communication | Brief Report: Association of Inflammation With Development of Erosions in Patients With Hand Osteoarthritis: A Prospective Ultrasonography Study. | 26414489 |
| Degenerative polyarthritis, Inflammation | Altered Intercellular Communication | To investigate the association between features of ultrasound-detected inflammation and development of erosive disease in patients with hand osteoarthritis (OA) over 2.3 years of followup. | 26414489 |
| Inflammation, Superficial ulcer | Altered Intercellular Communication | Persistent inflammation was particularly associated with the development of erosions. | 26414489 |
| Degenerative polyarthritis, Inflammation, Superficial ulcer | Altered Intercellular Communication | Ultrasound-detected features of inflammation are associated with the development of erosions in patients with hand OA, suggesting that inflammation plays a role in the pathogenesis of hand OA and could be a therapeutic target. | 26414489 |
| Inflammation, Tumor necrosis, HIV Infections | Altered Intercellular Communication | Chronic inflammation marked by elevated interleukin (IL)-6, soluble tumor necrosis factor (TNF)-a receptor (sTNFR)-1, and sTNFR-2 levels may play a detrimental role in aging and HIV infection. | 26414536 |
| Inflammation, HIV Infections | Altered Intercellular Communication | These findings provide initial insight into the in vivo relationship between TNF-a activation and IL-6 and a basis for further investigations into potential mechanisms underlying chronic inflammation in aging and HIV infection. | 26414536 |
| Inflammation | Altered Intercellular Communication | When acting as allergens to induce type I responses, microscopic agents other than parasites in the intestinal tract could induce eosinophilic inflammation in the liver. | 26414822 |
| Inflammation, Brain Injury, Chronic, Fibrosis Assessment | Altered Intercellular Communication | It protects kidney against acute and chronic injury, inflammation and fibrosis. | 26415312 |
| Inflammation | Altered Intercellular Communication | A 71-year-old man was referred to our department due to inflammation in the right scrotum. | 26415366 |
| Inflammation, Inflammatory dermatosis | Altered Intercellular Communication | AA patients have a higher incidence of various T-cell-driven inflammatory skin diseases than the normal population, a phenomenon which might relate to over-activation of skin-homing T cells and to specific immune triggers as the primary cause of inflammation. | 26416203 |
| Inflammation | Altered Intercellular Communication | The results indicate that terrein has an alleviative function of age-related inflammation characterized as an anti-oxidant. | 26416516 |
| Cerebral Small Vessel Diseases, Inflammation | Altered Intercellular Communication | Perivascular spaces (PVS) are associated with ageing, cerebral small vessel disease, inflammation and increased blood brain barrier permeability. | 26416614 |
| Canaliculitis, Inflammation, Lacrimation | Altered Intercellular Communication | Among the 14 patients, lacrimal punctal granuloma formation occurred in 3 patients, tearing occurred in 6 patients, canaliculitis occurred in 3 patients, and chronic inflammation of the ocular surface occurred in 2 patients. | 26418430 |
| Inflammation | Altered Intercellular Communication | During wound healing after surgery, physiological inflammation leads to an increase in soft tissue perfusion. | 26419379 |
| Inflammation, Neurogenic Inflammation, Cirrhotic, Liver Failure | Altered Intercellular Communication | The expression levels of prolyl oligopeptidase responds not only to neuroinflammation but also to systemic inflammation upon liver failure in rat models and cirrhotic patients. | 26420028 |
| Inflammation, Cirrhotic | Altered Intercellular Communication | Levels of several pro-inflammatory cytokines and those of NO/cGMP homeostasis metabolites were measured in PCS rats and cirrhotic patients to conclude on the role of PREP in inflammation. | 26420028 |
| Inflammation | Altered Intercellular Communication | Low haemoglobin levels contribute to low grip strength independent of low-grade inflammation in Japanese elderly women. | 26420185 |
| Inflammation, Carcinogenesis, Infection caused by Helicobacter pylori | Altered Intercellular Communication | Chronic inflammation of gastric mucosa by Helicobacter pylori infection can initiate gastric carcinogenesis. | 26420253 |
| Inflammation, Carcinogenesis, Stomach Carcinoma | Altered Intercellular Communication | As angiopoietin-like protein 2 (ANGPTL2) mediates inflammation and inflammation-associated carcinogenesis, we investigated the functional and clinical significance of ANGPTL2 in human gastric cancer (GC). | 26420253 |
| Inflammation, Diabetic Retinopathy, GDC Disease Response Terminology | Altered Intercellular Communication | Inflammation is one important mechanism of diabetic retinopathy (DR). | 26420914 |
| Inflammation, Disorder characterized by fever | Altered Intercellular Communication | Inflammation can occur during the febrile illness or months later and can manifest in a variety of ways. | 26421893 |
| Chikungunya Fever, Inflammatory abnormality of the eye, Uveitis | Altered Intercellular Communication | Given the wide variety of presentations, chikungunya fever-related uveitis should be included in the differential diagnosis of all at-risk patients presenting with acute ocular inflammation, particularly those traveling from endemic regions. | 26421893 |
| Inflammation, Primary malignant neoplasm, Atrophic | Altered Intercellular Communication | Prevalences of cancer, HGPIN, atrophy, or inflammation posttreatment were similar; however, more extensive atrophy and less extensive HGPIN was more common in the lycopene group. | 26422197 |
| Inflammation, HIV Antigens | Altered Intercellular Communication | Whether the reported high risk of age-related diseases in HIV-infected people is caused by biological ageing or HIV-associated risk factors such as chronic immune activation and low-grade inflammation is unknown. | 26423253 |
| Inflammation, Squamous cell carcinoma of esophagus | Altered Intercellular Communication | The clinical significance of systemic inflammation score in esophageal squamous cell carcinoma. | 26423404 |
| Squamous cell carcinoma of esophagus | Altered Intercellular Communication | SIS was a novel and promising inflammation-based prognostic score than PNI in ESCC patients who underwent esophagectomy. | 26423404 |
| Inflammation, Folliculitis | Altered Intercellular Communication | The widespread dermis inflammation was more frequent in severe EPPEs and in patients treated with cetuximab, while the hair follicle inflammation was observed only in mild/moderate EPPEs. | 26423594 |
| Granulomatous inflammation, Tuberculosis | Altered Intercellular Communication | Therefore, we proceeded with laparoscopy which showed multiple nodular deposits on abdominal wall, bowel and omentum and peritoneal biopsy revealed granulomatous inflammation with caseous type necrosis compatible with mycobacterium tuberculosis infection. | 26423615 |
| Inflammation, Portal Vein Thrombosis, Tuberculosis | Altered Intercellular Communication | This was confirmed by tuberculosis genome identification on the biopsy sample confirming a diagnosis of peritoneal tuberculosis with secondary portal vein thrombosis and cavernous formation due to local inflammation. | 26423615 |
| Hepatic inflammation | Altered Intercellular Communication | Serum levels of hepatic inflammation enzymes along with fatty liver changes were significantly elevated by DEP exposure. | 26423653 |
| Inflammation, Dental Plaque, Ischemic stroke, Atherosclerosis | Altered Intercellular Communication | Cytochrome P450s (CYP450) enzymes regulate inflammation and atherosclerosis and can affect carotid plaque stability in patients with ischemic stroke (IS). | 26423716 |
| ARCN1 gene, Inflammation, Chronic Obstructive Airway Disease | Altered Intercellular Communication | Chronic Obstructive Pulmonary Disease (COPD) is characterized by lung and systemic inflammation as well as airway goblet cell hyperplasia (GCH). | 26424214 |
| Inflammation, Peri-Implantitis | Altered Intercellular Communication | The present data suggest that the increased levels of the selected PICF-derived biomarkers of periodontal tissue inflammation, matrix degradation/regulation, and alveolar bone turnover/resorption combined with site-specific microbial profiles may be associated with peri-implantitis and could have potential as predictors of peri-implant diseases. | 26424287 |
| Inflammation, Non-Small Cell Lung Carcinoma, Malignant Neoplasms | Altered Intercellular Communication | The immunological status, consisting of "inflammation status" and "nutritional condition," is important for the survival of patients with various cancers, including non-small cell lung cancer (NSCLC). | 26424708 |
| Inflammatory Bowel Diseases, Anxiety, CTCAE 3.0, Inflammation, Depression, CTCAE | Altered Intercellular Communication | Mind-body interventions, such as BBMW, which emphasize Voluntarily Regulated Breathing Practices, may have significant long-lasting benefits for IBD symptoms, anxiety, depression, quality of life, and inflammation. | 26426148 |
| Retinal Detachment, Oculovestibuloauditory syndrome, Choroiditis | Altered Intercellular Communication | This is the first known case of a serous neurosensory retinal detachment from suspected choroidal inflammation associated with Cogan syndrome. | 26426408 |
| Inflammatory Bowel Diseases, Inflammation | Altered Intercellular Communication | Among seven patients undergoing colonoscopy because of a suspicion of inflammatory bowel disease, five were free of pathological signs and two patients with pathological endoscopy findings had nonspecific inflammation as documented by histopathological examination. | 26426964 |
| Inflammation, Nephrogenic metaplasia | Altered Intercellular Communication | Nephrogenic adenoma, also referred to nephrogenic metaplasia, is a benign proliferative lesion of urothelium, usually associated with chronic physical stimuli or inflammation. | 26428868 |
| Inflammation, Vesico-Ureteral Reflux, Nephrogenic metaplasia | Altered Intercellular Communication | There is a possibility that control of inflammation caused by the surgery for vesicoureteral reflux in the local site didn't work well on the background of heterozygous mutation of MEFV gene, and as a result, nephrogenic adenoma appeared. | 26428868 |
| Inflammation | Altered Intercellular Communication | Regulation of HBV-specific CD8(+) T cell-mediated inflammation is diversified in different clinical presentations of HBV infection. | 26428923 |
| Malignant neoplasm of liver, Acute and chronic inflammation, Liver Cirrhosis | Altered Intercellular Communication | Chronic HBV infection is the leading cause of liver cirrhosis and hepatic cancer, but the individual responses toward HBV infection are highly variable, ranging from asymptomatic to chronic active hepatitis B inflammation. | 26428923 |
| Inflammation | Altered Intercellular Communication | In this study, we hypothesized that the different individual responses to HBV infection was associated with differences in HBV-specific CD8(+) T cell-mediated inflammation and cytotoxicity. | 26428923 |
| Inflammation, Molluscum Contagiosum | Altered Intercellular Communication | The microscopic examination revealed bud-like proliferation of the epidermis, molluscum bodies and moderate chronic inflammation of the dermis. | 26429183 |
| Inflammation, Smoking | Altered Intercellular Communication | Smoking is a well-known risk factor for inflammation. | 26429291 |
| Inflammation, HIV | Altered Intercellular Communication | Low zinc levels and chronic inflammation are common in individuals infected with human immunodeficiency virus (HIV). | 26429417 |
| Inflammation | Altered Intercellular Communication | Zinc deficiency may promote systemic inflammation, but research on the role of zinc in inflammation among HIV-positive individuals taking account of anti-retroviral therapy is lacking. | 26429417 |
| Degenerative polyarthritis | Altered Intercellular Communication | These include intra-articular structures (degenerative arthritis, and inflammatory conditions) as well as extra-articular structures (ligaments, muscles, etc. | 26431131 |
| Fever, CTCAE | Altered Intercellular Communication | Fever appeared to be aggravated by acetaminophen and more related to the elevation of hepatic enzymes than to the change in the inflammation-related cytokines. | 26431202 |
| Parkinson Disease, Inflammation, RNA Recognition Motif | Altered Intercellular Communication | Investigation on Abnormal Iron Metabolism and Related Inflammation in Parkinson Disease Patients with Probable RBD. | 26431210 |
| Parkinson Disease, Inflammation, palladium, REM Sleep Behavior Disorder | Altered Intercellular Communication | To investigate potential mechanisms involving abnormal iron metabolism and related inflammation in Parkinson disease (PD) patients with probable rapid eye movement sleep behavior disorder (PRBD). | 26431210 |
| Inflammation, Chronic Kidney Diseases, Metabolic Syndrome X | Altered Intercellular Communication | Chronic Kidney Disease in Non-Diabetic Older Adults: Associated Roles of the Metabolic Syndrome, Inflammation, and Insulin Resistance. | 26431218 |
| Inflammation, Metabolic Syndrome X, Chronic Kidney Diseases | Altered Intercellular Communication | We also explored two possible pathways linking the metabolic syndrome with CKD: inflammation as measured by high sensitivity C-Reactive Protein (hsCRP) and insulin resistance as measured by HOMA-IR. | 26431218 |
| Dyslipidemias, Metabolic Syndrome X | Altered Intercellular Communication | A Larger Body Mass Index is Associated with Increased Atherogenic Dyslipidemia, Insulin Resistance, and Low-Grade Inflammation in Individuals with Metabolic Syndrome. | 26431271 |
| ARCN1 gene, Inflammation, Hypoxia | Altered Intercellular Communication | Our study indicated that serum IMA, ox-LDL, and TOS may be increased as a result of chronic hypoxia, inflammation, and oxidative stress in patients with severe and very severe stable COPD. | 26431591 |
| Pain Distress Question, Peritoneal Diseases, Tenosynovitis | Altered Intercellular Communication | Peroneal tendon disorders, including the tendon sheath inflammatory condition tenosynovitis, are a major cause of chronic lateral ankle pain. | 26432083 |
| Inflammation, Neoplasm Metastasis, Neoplasms | Altered Intercellular Communication | Inflammation can promote tumor growth, invasion, angiogenesis and even metastasis. | 26432433 |
| Inflammation, Damage, Demyelination | Altered Intercellular Communication | Secondary outcomes were other CSF biomarkers of inflammation, axonal damage and demyelination; clinical scores; magnetic resonance imaging measures of disease activity, magnetization transfer ratio (MTR) and diffusion tensor imaging (DTI); motor evoked potentials; and bone density scans. | 26432857 |
| Inflammation, Chronic sinusitis, Craniosynostosis | Altered Intercellular Communication | Inflammation plays a central role in the pathogenesis of chronic rhinosinusitis (CRS), and TNFa is a key pro-inflammatory cytokine in the pathogenesis of this disease. | 26433033 |
| Inflammation | Altered Intercellular Communication | SCC/MCC is aggressive, arising within elderly patients' chronically ultraviolet-exposed skin, often in the setting of immunosuppression or inflammation. | 26433246 |
| Inflammation, CHOP regimen, Arthritis, Psoriatic | Altered Intercellular Communication | Effect of tight control of inflammation in early psoriatic arthritis (TICOPA): a UK multicentre, open-label, randomised controlled trial. | 26433318 |
| Inflammation, Rheumatoid Arthritis, Arthritis, Psoriatic | Altered Intercellular Communication | Early intervention and tight control of inflammation optimise outcomes in rheumatoid arthritis but these approaches have not yet been studied in psoriatic arthritis. | 26433318 |
| Airway structure, Asthma, Atopy | Altered Intercellular Communication | Meanwhile, fractional exhaled nitric oxide (FeNO) concentration, used in assessing airway inflammation in bronchial asthma, is known to be affected by atopic disposition. | 26433532 |
| Hyperplasia, Arteritis | Altered Intercellular Communication | These failures are primarily due to the development of neointimal hyperplasia, resulting from arterial wall inflammation. | 26433546 |
| Inflammation, Depression, CTCAE, Endothelial dysfunction | Altered Intercellular Communication | Association of Type D personality with increased vulnerability to depression: Is there a role for inflammation or endothelial dysfunction? | 26433759 |
| Inflammation, Depression, CTCAE, Endothelial dysfunction | Altered Intercellular Communication | We examined whether (1) Type D is a vulnerability factor for depression in general, (2) Type D is associated with inflammation or endothelial dysfunction, and (3) these biomarkers alter the possible association between Type D and depression. | 26433759 |
| Inflammation, Endothelial dysfunction | Altered Intercellular Communication | Multivariable regression analyses showed that Type D was associated with inflammation (b=0.228, p=0.014) and endothelial dysfunction (b=0.216, p=0.022). | 26433759 |
| Inflammation, Depression, CTCAE, Endothelial dysfunction | Altered Intercellular Communication | Type D personality may be a vulnerability factor for depression, irrespective of levels of inflammation or endothelial dysfunction. | 26433759 |
| Dyspnea, Inflammation | Altered Intercellular Communication | This study set out to examine the relative importance of potential contributors to dyspnea, ie, disease severity, inflammation and psychologic distress in a large prospective cohort of chronic HF patients. | 26435096 |
| ARCN1 gene, Inflammation, Anxiety, CTCAE 3.0, Chronic Obstructive Airway Disease, Depression, CTCAE, Dyspnea | Altered Intercellular Communication | Linear mixed modeling analysis with maximum likelihood estimation showed that when determinant clusters were entered separately, comorbid chronic obstructive pulmonary disease (COPD) was significantly associated with dyspnea complaints (P = .039), as were depression (P < .001) and anxiety (P < .001), whereas inflammation did not significantly affect dyspnea complaints. | 26435096 |
| Inflammation, Medically Unexplained Symptoms, hafnium, Dyspnea, Overweight | Altered Intercellular Communication | The experience and report of dyspnea in HF is determined foremost by somatic symptoms of psychologic distress, being of older age, being overweight, and having comorbid COPD, with disease severity and systemic inflammation levels playing an ancillary role. | 26435096 |
| Inflammation | Altered Intercellular Communication | Interleukin- (IL-) 37 is a novel anti-inflammatory cytokine that suppresses immune response and inflammation. | 26435567 |
| glycation, Inflammation | Altered Intercellular Communication | The S100 family and receptor for advanced glycation end products (RAGE) participate in regulating inflammation, even in the production of matrix metalloproteinases (MMPs). | 26436377 |
| Inflammation, Hyperkeratosis | Altered Intercellular Communication | No subungual debris, hyperkeratosis, or paronychial inflammation was present in the affected nail. | 26437286 |
| Inflammation, Chronic lung disease | Altered Intercellular Communication | It has gained interest as a biological marker in chronic lung diseases because of its presumed relationship to inflammation. | 26439880 |
| Inflammation | Altered Intercellular Communication | PRX5 elevation in MG could be related to the neuromuscular junction breakdown and plays a pivotal role in the pathogenic inflammation of MG. | 26439955 |
| T-Lymphocyte, Inflammation, Lupus Erythematosus, Lupus Erythematosus, Systemic | Altered Intercellular Communication | T lymphocyte hyperactivity and progressive inflammation in systemic lupus erythematosus (SLE) patients results in over-expression of human leucocyte antigen (HLA)-Ib on the surface of lymphocytes. | 26440212 |
| Inflammation | Altered Intercellular Communication | These are shed into the circulation upon inflammation, and may augment production of antibodies promoting pathogenicity of the disease. | 26440212 |
| Inflammation, Stanford Cancer Institute, Immune System Diseases, Infection | Altered Intercellular Communication | These data support additional functional studies of T cells isolated from individuals with chronic SCI, where alterations in T cell homeostasis may contribute to immune dysfunction, such as immunity against infections or the persistence of chronic inflammation. | 26440591 |
| Inflammation, Coronary microvascular dysfunction, Coronary Artery Disease, CAMPOMELIC DYSPLASIA, Chronic inflammatory disorder | Altered Intercellular Communication | Chronic inflammatory disease (CID) is a complex multisystem disease characterized by chronic inflammation, which can lead to coronary microvascular dysfunction (CMD) and can also predispose to coronary artery calcium deposition, even in the absence of obstructive coronary artery disease. | 26443046 |
| Airway structure | Altered Intercellular Communication | Fractional exhaled nitric oxide (FeNO) is a noninvasive biomarker of eosinophilic airway inflammation. | 26443435 |
| Prediabetes syndrome, Erectile dysfunction | Altered Intercellular Communication | Hormonal determinants of erectile dysfunction and lower urinary tract symptoms in middle-aged and elderly men with prediabetes. | 26444448 |
| Inflammation, Neoplasms | Altered Intercellular Communication | Inflammation is a critical component of tumor progression. | 26444485 |
| Stomach Carcinoma | Altered Intercellular Communication | It has been widely accepted that gastric cancer is an inflammation-driven cancer. | 26444485 |
| Inflammation, physiopathological | Altered Intercellular Communication | Potentially, the increase of SBPV will aggravate venous wall inflammation and may play a role in AVF dysfunction. | 26444591 |
| Inflammation, Lower Urinary Tract Symptoms, Depression, CTCAE | Altered Intercellular Communication | Inflammation has recently been identified as an independent risk factor for LUTS and depression. | 26445118 |
| Anxiety, CTCAE 3.0, Inflammation, Lower Urinary Tract Symptoms, Depression, CTCAE | Altered Intercellular Communication | This study aimed to assess the association between depression, anxiety and LUTS, and the moderating influence of systemic inflammation, in the presence of other biopsychosocial confounders. | 26445118 |
| Acute inflammation, Hemorrhagic diarrhea | Altered Intercellular Communication | It causes bouts of acute intestinal inflammation, in an unpredictable relapsing-remitting course, with bloody diarrhoea and extreme urgency to access a toilet. | 26445224 |
| Inflammation | Altered Intercellular Communication | We speculate that the former may be due to systemic inflammation and the latter to a higher socio-economic status. | 26446117 |
| Inflammation | Altered Intercellular Communication | BT alteration in these patients may be associated with brain perfusion and metabolism rather than other factors such as systemic inflammation and body temperature. | 26446147 |
| Retinitis | Altered Intercellular Communication | APOE Isoforms Control Pathogenic Subretinal Inflammation in Age-Related Macular Degeneration. | 26446211 |
| Inflammation, Hyperplastic Polyp | Altered Intercellular Communication | In the context of APOE-dependent subretinal inflammation in Cx3cr1(GFP/GFP) mice, the APOE4 allele led to diminished APOE and CCL2 levels and protected Cx3cr1(GFP/GFP) mice against harmful subretinal MP accumulation observed in Cx3cr1(GFP/GFP)TRE3 mice. | 26446211 |
| methyldopa, Inflammation, Abnormal degeneration | Altered Intercellular Communication | Our study is the first to show how APOE2 provokes and APOE4 inhibits the cardinal AMD features, inflammation, degeneration, and exaggerated neovascularization. | 26446211 |
| methyldopa, Inflammation | Altered Intercellular Communication | They emphasize the role of APOE in inflammation and inflammation in AMD. | 26446211 |
| Kimura Disease | Altered Intercellular Communication | Kimura's disease is a rare, chronic inflammatory condition of unknown etiology; with a predilection in the head and neck region. | 26446335 |
| Inflammation, Islet Cell Tumor | Altered Intercellular Communication | FP PET/CT results were due to unspecific liver uptake, post-surgical inflammation and pancreatic neuroendocrine tumour. | 26446694 |
| Pain Distress Question, Inflammation, hyperthermia treatment | Altered Intercellular Communication | However, we report the unusual aspect of the bone scan in a 3-year-old child who was referred to explore an isolated pain of his lower left limb, with hyperthermia and markers of inflammation. | 26447375 |
| Communicable Diseases, Aortitis | Altered Intercellular Communication | Aortitis is a generic term defined as an inflammatory condition involving the aortic wall, of infectious or noninfectious origin. | 26447376 |
| Inflammation, gastrointestinal, Granuloma | Altered Intercellular Communication | Anisakis can produce persistent local inflammation and granuloma, and larvae have been incidentally found in gastrointestinal (GI) tumors. | 26448021 |
| Bone Diseases, HD Term Type, Inflammation, Calcinosis | Altered Intercellular Communication | The markers studied here may be involved in the calcification of vessels seen in HD patients due to a combination of inflammation and bone disease. | 26448366 |
| Inflammation, Morbidity - disease rate | Altered Intercellular Communication | Mini-extracorporeal circulation (MECC) units were developed to reduce postoperative morbidity, transfusion requirements, and inflammation associated with conventional on-pump coronary artery bypass (ONCAB) surgery without the technical demands of the off-pump (OPCAB) technique. | 26448506 |
| Refractory anemias, Inflammation, Rheumatoid Arthritis | Altered Intercellular Communication | IL-1b is involved in the induction and maintenance of chronic inflammation in rheumatoid arthritis (RA). | 26448682 |
| Inflammation, Metabolic Syndrome X | Altered Intercellular Communication | We are first to observe a selective increase in monocyte p38 mitogen-activated protein kinase activity in metabolic syndrome and suggest it as a pivotal molecular target for ameliorating insulin resistance and inflammation. | 26449239 |
| Inflammation, Neoplasms, S100A4 protein, human, Communicable Diseases, Virus Diseases | Altered Intercellular Communication | It has been estimated that 15%-20% of human tumours are driven by infection and inflammation, and viral infections play an important role in malignant transformation. | 26449432 |
| Inflammation, Osteoporosis, Postmenopausal | Altered Intercellular Communication | Given the important role of IL-31 in inflammation, we measured its serum levels in postmenopausal osteoporotic patients. | 26449657 |
| Inflammation, Diabetes Mellitus | Altered Intercellular Communication | Adipose tissue inflammation contributes to the development of complications, such as insulin resistance and type 2 diabetes mellitus. | 26449750 |
| Inflammation, Myeloid Leukemia, Chronic | Altered Intercellular Communication | We previously reported that plasma levels of N(e)-(carboxymethyl)lysine (CML) were decreased in obese subjects resulting from CML accumulation in adipose tissue and that this CML accumulation plays an important role in adipose tissue inflammation. | 26449750 |
| Inflammation, Myeloid Leukemia, Chronic, Obesity, Abdominal, Obesity | Altered Intercellular Communication | Obesity, in particular central obesity, is characterized by greater levels of LGI but by lower levels of circulating CML; the latter significantly explaining a portion of the positive association between central obesity and inflammation. | 26449750 |
| Inflammation | Altered Intercellular Communication | The avb6 integrin is a cell surface adhesion molecule that plays critical roles in the injury and inflammation processes. | 26449830 |
| Inflammation | Altered Intercellular Communication | Elevated risperidone serum concentrations during acute inflammation, two cases. | 26449925 |
| Seizures, Inflammation, selenium, Status Epilepticus | Altered Intercellular Communication | Acute-phase proteins, such as procalcitonin (PCT), C-reactive protein (CRP) and albumin, may relate with course and outcome in status epilepticus (SE), as seizures bring about inflammation, changes of cytokine levels and blood-brain barrier breakdown. | 26450065 |
| Inflammation, Urinary tract infection | Altered Intercellular Communication | As urinary tract infection (UTI) represents a common source of inflammation during pregnancy, we tested whether presence of UTI during pregnancy increased the odds of developing PE. | 26450405 |
| Inflammation, hypertensive nephropathy | Altered Intercellular Communication | Inflammation mediated by nuclear factor-kB (NF-kB) plays a critical role in the pathogenesis of hypertensive nephropathy (HN). | 26450610 |
| Inflammation, Atherosclerosis | Altered Intercellular Communication | Convincing evidence has identified inflammation as an initiator of atherosclerosis, underpinning CVD. | 26450630 |
| Inflammation | Altered Intercellular Communication | We investigated (i) whether dietary inflammation, as measured by the 'dietary inflammatory index (DII)', was predictive of 5-year CVD in men and (ii) its predictive ability compared with that of SFA intake alone. | 26450630 |
| vascular inflammations | Altered Intercellular Communication | CVD clinical guidelines and public health recommendations may have to expand to include dietary patterns in the context of vascular inflammation. | 26450630 |
| Communicable Diseases, Noninfiltrating Intraductal Carcinoma, Inflammation | Altered Intercellular Communication | Development of DCI is multifactorial, and inflammation, with or without infection, is one of the factors independently associated with development of DCI and poor outcome. | 26450848 |
| Inflammation, Inflammatory disorder | Altered Intercellular Communication | Etiologies were divided into 3 prognostic categories: Group 1, chemical injuries (7 eyes); Group 2, immune-based inflammation (4 eyes); and Group 3, noninflammatory diseases (9 eyes). | 26451369 |
| Communicable Diseases, Inflammation, Parasitemia, Skeletal muscle structure | Altered Intercellular Communication | Consistent with these data, Gal-1 deficient (Lgals1-/-) mice showed increased parasitemia, reduced signs of inflammation in heart and skeletal muscle tissues, and lower survival rates as compared to wild-type (WT) mice in response to intraperitoneal infection with T. cruzi Tulahuen strain. | 26451839 |
| Takayasu Arteritis | Altered Intercellular Communication | Contrast-enhanced ultrasonography in Takayasu arteritis: watching and monitoring the arterial inflammation. | 26452525 |
| Vasculitis | Altered Intercellular Communication | This pathological enhancement indicates neovascularisation of the arterial wall, which is supposed to correlate with active vascular inflammation. | 26452525 |
| Refractory anemias, Rheumatoid Arthritis, Arthritis | Altered Intercellular Communication | In rheumatoid arthritis (RA), treat-to-target strategies require instruments for valid detection of joint inflammation. | 26452538 |
| Inflammation | Altered Intercellular Communication | We developed and validated within the same cohort an algorithm for detection of joint inflammation by OST with US as reference. | 26452538 |
| Refractory anemias, Inflammation | Altered Intercellular Communication | In this pilot study, OST performed moderately in the detection of joint inflammation in patients with RA. | 26452538 |
| Inflammation, Breast Carcinoma | Altered Intercellular Communication | Breast cancer risk reduction may be possible for U.S. women with dietary consumption of higher o-3, which has anti-inflammatory properties, in concert with lower o-6, which induces inflammation. | 26452606 |
| Inflammation, Fever, CTCAE, Anemia | Altered Intercellular Communication | We discuss the clinical and pathologic features of this lesion suggesting that its regressive changes may be associated with inflammation and can cause systemic symptoms such as fever and anemia. | 26453091 |
| Airway structure | Altered Intercellular Communication | Airway inflammation and proinflammatory mediators in lung tissue and BAL fluid were determined. | 26453516 |
| HD Term Type, Inflammation, Cardiovascular Diseases | Altered Intercellular Communication | Emerging evidence highlights the strong correlation of oxidative stress with chronic inflammation and cardiovascular disease, which are highly prevalent in most patients on maintenance haemodialysis (HD) and are a major risk factor for mortality in this population. | 26453922 |
| Nonalcoholic Steatohepatitis, Inflammation, Fibrosis Assessment, Diabetes Mellitus, Fatty Liver Disease | Altered Intercellular Communication | Nine hundred and thirty-nine participants in the Edinburgh Type 2 Diabetes Study underwent investigation including liver ultrasound and non-invasive measures of non-alcoholic steatohepatitis (NASH), hepatic fibrosis and systemic inflammation. | 26454513 |
| Inflammation, Fibrosis Assessment, Chronic liver disease, Fatty Liver Disease | Altered Intercellular Communication | Higher levels of systemic inflammation, NASH and hepatic fibrosis markers were associated with both unknown prevalent and incident clinically significant chronic liver disease (allP < 0.001). | 26454513 |
| Diabetes Mellitus | Altered Intercellular Communication | Brain-derived neurotrophic factor (BDNF) is associated with systemic inflammatory conditions, such as diabetes. | 26454822 |
| Cholangiocarcinoma, FBN2 wt Allele, Malignant Neoplasms, Inflammation | Altered Intercellular Communication | Cholangiocarcinoma (CCA), which is a poor prognosis malignancy that arises from the malignant transformation of cholangiocytes, is associated with chronic inflammation of the biliary epithelium. | 26455324 |
| Inflammation, FBN2 wt Allele | Altered Intercellular Communication | Thus far, the molecular mechanisms of the origin and neoplastic processes of CCA that are promoted by inflammation are still unclear and need to be fully elucidated. | 26455324 |
| Inflammation, Primary malignant neoplasm, FBN2 wt Allele | Altered Intercellular Communication | Surprisingly, let-7c/miR-99a/miR-125b cluster also significantly decreased the ability of CCA cells for cancer stem cell-like mammosphere generation by downregulating CD133 and CD44, which suggests the pivotal roles of let-7c, miR-99a and miR-125b in CCA by regulating both inflammation and stem-like properties. | 26455324 |
| Inflammation, Acute Coronary Syndrome | Altered Intercellular Communication | Levels of High-Density Lipoprotein Cholesterol are Associated With Biomarkers of Inflammation in Patients With Acute Coronary Syndrome. | 26456205 |
| Pain Distress Question, Inflammation | Altered Intercellular Communication | Emerging evidence proposes a link between immune changes and pain, which is consistent with the inflammation theory of aging and the increased incidence of age-related diseases. | 26456458 |
| Inflammation, Pain Distress Question | Altered Intercellular Communication | Sterile inflammation after intravitreal aflibercept injection typically presents without pain, and the visual outcomes are generally favorable. | 26457038 |
| Inflammation, Atherosclerosis | Altered Intercellular Communication | Circulating and coronary CTRP9 plays an important role in the inflammation and coronary atherosclerosis of CAD patients. | 26457306 |
| Inflammation | Altered Intercellular Communication | Distinct lymphocyte subpopulations have been implicated in the regulation of glucose homeostasis and obesity-associated inflammation in mouse models of insulin resistance. | 26458065 |
| vascular inflammations | Altered Intercellular Communication | [A case of MPO-ANCA positive hypertrophic pachymeningitis associated with vascular inflammation in the kidney biopsy]. | 26458570 |
| vascular inflammations | Altered Intercellular Communication | The presence of vascular inflammation in the kidney biopsy led us to consider that this patient may show progression to the systemic type of MPO-ANCA-positive hypertrophic pachymeningitis. | 26458570 |
| Inflammation, Rosacea | Altered Intercellular Communication | The intensity of perifollicular inflammation and the presence of follicular inflammatory reactions were dependent on the severity of rosacea in both subtype groups. | 26460622 |
| Mesenteric Panniculitis | Altered Intercellular Communication | Mesenteric panniculitis is an underdiagnosed inflammatory condition of unknown etiology that involves the mesenteric adipose tissue. | 26462046 |
| Inflammation, Ischemia | Altered Intercellular Communication | Inflammation is associated with a reduced number of pro-angiogenic Tie-2 monocytes and endothelial progenitor cells in patients with critical limb ischemia. | 26462497 |
| CLU protein, human, Ischemia, Inflammation | Altered Intercellular Communication | Critical limb ischemia (CLI) is characterized by a severe, chronic inflammatory response; thus, progression of the disease might be related to the deleterious effects of inflammation on pro-angiogenic cells. | 26462497 |
| CLU protein, human, Inflammation | Altered Intercellular Communication | We found a strong association of diverse inflammatory markers with a reduced proportion of pro-angiogenic TEM or EPC in patients with CLI, giving rise to the speculation that a severe chronic inflammation might lead to deleterious effects on TEM and EPC, possibly interfering with angiogenesis, thus promoting an aggravation of the disease. | 26462497 |
| Inflammation, Diverticulitis, Diverticulum | Altered Intercellular Communication | He was diagnosed with diverticular colitis based on findings of redness around diverticula in the sigmoid colon and biopsy findings of non-specific inflammation. | 26464173 |
| Interstitial inflammation, Swelling, Syphilis, Dermatitis, Acanthosis | Altered Intercellular Communication | Combinations of endothelial swelling, interstitial inflammation, irregular acanthosis, and elongated rete ridges should raise the possibility of syphilis, along with the presence of vacuolar interface dermatitis with a lymphocyte in nearly every vacuole and lymphocytes with visible cytoplasm. | 26464219 |
| Inflammation, Asthma | Altered Intercellular Communication | In asthma, inflammation affects both the proximal and distal airways and may induce significant hyperinflation (HI). | 26466328 |
| ARCN1 gene, Inflammation, Pancreatitis, Sarcoidosis, Chronic Obstructive Airway Disease, Inflammatory disorder, MS gene | Altered Intercellular Communication | To further discriminate between disease-specific and general inflammation we included miRNA expression data from other inflammatory diseases (inflammation controls (IC): 24 chronic obstructive pulmonary disease (COPD), 23 multiple sclerosis, 38 pancreatitis and 45 sarcoidosis cases) as well as 70 healthy controls from previous studies. | 26466382 |
| Inflammation, Cerebral Aneurysm, Rupture | Altered Intercellular Communication | A growing body of evidence suggests that inflammation plays a crucial role in cerebral aneurysm initiation, progression, and rupture. | 26466586 |
| Inflammation, Nephrosclerosis, Brucellosis | Altered Intercellular Communication | The present case demonstrates that persistent subclinical inflammation can lead to malignant nephrosclerosis in familial Mediterranean fever patients with this genotype. | 26466703 |
| Adult-Onset Still Disease, Orbital Pseudotumor | Altered Intercellular Communication | Orbital inflammation has been rarely associated with adult-onset Still's disease (AOSD). | 26466709 |
| Inflammation, Enlargement of lacrimal gland | Altered Intercellular Communication | We herein describe two AOSD patients who developed lacrimal gland enlargement with inflammation spreading to the contiguous tissues in the orbit. | 26466709 |
| Dacryoadenitis, Orbital Pseudotumor | Altered Intercellular Communication | We speculate that dacryoadenitis and orbital inflammation are manifestations of AOSD. | 26466709 |
| Autoimmune Diseases, Rheumatoid Arthritis, Inflammation | Altered Intercellular Communication | Rheumatoid arthritis is an autoimmune disease characterized by joint inflammation that affects approximately 1% of the general population. | 26466969 |
| Inflammation, Neoplasms | Altered Intercellular Communication | Comparisons of CD66b and the CD66b/CD3 ratio according to N status, tumour location, recurrence, inflammation grade, and histological grade did not reach statistical significance. | 26467671 |
| methyldopa, Inflammation | Altered Intercellular Communication | Our results show that SNPs associated with complement activation and inflammation significantly contribute to AMD risk, separately from the risk explained by the 19 known risk SNPs. | 26467978 |
| Inflammation | Altered Intercellular Communication | Tangeretin from Citrus reticulate Inhibits Respiratory Syncytial Virus Replication and Associated Inflammation in Vivo. | 26468759 |
| Pneumonitis | Altered Intercellular Communication | Moreover, a luminex assay indicated tangeretin relieved RSV-induced lung inflammation by attenuating interleukin (IL)-1b secretion. | 26468759 |
| Inflammation, Respiratory Syncytial Virus Infections, Pneumonitis | Altered Intercellular Communication | This study demonstrates that tangeretin inhibited RSV replication and RSV-induced lung inflammation in vivo and may be useful in preventing and treating RSV infections and inflammation. | 26468759 |
| Inflammation, Chronic Obstructive Airway Disease, Failure (biologic function) | Altered Intercellular Communication | Chronic obstructive pulmonary disease is characterized, in part, by chronic inflammation that persists even after smoking cessation, suggesting that a failure to resolve inflammation plays an important role in the pathogenesis of the disease. | 26468975 |
| Inflammation, Chronic Obstructive Airway Disease, Pulmonary Emphysema | Altered Intercellular Communication | Here, we report that proresolving signaling and metabolic pathways are disrupted in lung tissue from patients with chronic obstructive pulmonary disease, suggesting that supplementation with proresolving lipid mediators might reduce the development of emphysema by controlling chronic inflammation. | 26468975 |
| Cessation of life, Inflammation, Pulmonary Emphysema, Hypertrophy | Altered Intercellular Communication | Resolvin D1 was associated with a reduced development of cigarette smoke-induced emphysema and airspace enlargement, with concurrent reductions in inflammation, oxidative stress, and cell death. | 26468975 |
| Inflammation, Oral pain | Altered Intercellular Communication | ECC might negatively affect children's nutritional status, which might be mediated by the depth of decay, chronic inflammation, and mouth pain. | 26469655 |
| Diabetes Mellitus | Altered Intercellular Communication | Diabetes is already considered as an inflammatory condition with different cytokines being implicated in its physiopathology. | 26469782 |
| Inflammation, Dirofilariasis | Altered Intercellular Communication | The most frequent presentation of human dirofilariasis is a single submucosal nodule without signs of inflammation. | 26470974 |
| Inflammation, Scleritis | Altered Intercellular Communication | Bilateral posterior scleritis is an uncommon but severe inflammation of the posterior sclera. | 26471249 |
| Presenile dementia, Inflammation | Altered Intercellular Communication | Cerebral amyloid angiopathy-related inflammation: A potentially reversible cause of dementia with characteristic imaging findings. | 26471406 |
| Cerebral Amyloid Angiopathy, Inflammation | Altered Intercellular Communication | Cerebral amyloid angiopathy with inflammation (CAA-I) is a less well-recognized clinically and radiologically distinct subtype of CAA. | 26471406 |
| Inflammation | Altered Intercellular Communication | Contrast-enhancing MS lesions are important markers of active inflammation in the diagnostic work-up of MS and in disease monitoring with MR imaging. | 26471751 |
| Inflammation, Neoplasms | Altered Intercellular Communication | The occurrence of hyaluronan in smokers may have implications in the development of vocal fold inflammation and tumor initiation as hyaluronan is an important molecule in these processes. | 26471808 |
| Inflammation, Retinal Hemorrhage, Ocular Toxoplasmosis | Altered Intercellular Communication | To report a case with unilateral preexisting ocular toxoplasmosis (OT) and newly occurred active retinochoroidal inflammation associated with white-centered retinal hemorrhages (Roth spots) in the healthy eye. | 26472315 |
| Chorioretinitis | Altered Intercellular Communication | OT may be one differential diagnosis of patients suffering Roth spots in association with retinochoroidal inflammation. | 26472315 |
| Inflammation, Eosinophilic disorder, Communicable Diseases, Respiratory Syncytial Virus Infections, Respiratory Hypersensitivity | Altered Intercellular Communication | Blocking IL-33 with antibodies or using an IL-33 receptor knockout mouse during infection was sufficient to inhibit RSV immunopathogenesis (i.e., airway hyperresponsiveness, Th2 inflammation, eosinophilia, and mucus hyperproduction); whereas administration of IL-33 to adult mice during RSV infection was sufficient to induce RSV disease. | 26473724 |
| Refractory Cytopenia of Childhood, Inflammation, Pituitary Adenoma | Altered Intercellular Communication | Repeated chronic inflammation, such as under circumstances of ruptured Rathke's cleft cyst (RCC), is known as the fundamental basis of various pathological changes including neoplastic change, therefore to examine accurate incidence of pituitary adenomas is important for the preventive medicine. | 26473987 |
| Inflammation, Cyclophosphamide/Vincristine/Dacarbazine Regimen, Obesity, Cardiovascular Diseases | Altered Intercellular Communication | There is a complicated relationship between adipokines and low-grade inflammation in obesity and cardiovascular disease (CVD). | 26474157 |
| Inflammation, Diabetes Mellitus, Metabolic Syndrome X, Obesity | Altered Intercellular Communication | Health-Related Quality of Life in Relation to Obesity Grade, Type 2 Diabetes, Metabolic Syndrome and Inflammation. | 26474291 |
| Inflammation, Metabolic Syndrome X, ETV3 wt Allele, Obesity, Diabetes Mellitus, Non-Insulin-Dependent | Altered Intercellular Communication | These conditions are i) grade of obesity with and without type 2 diabetes (T2D), ii) metabolic syndrome (MetS), and iii) level of inflammation. | 26474291 |
| Inflammation, Diabetes Mellitus, Non-Insulin-Dependent, ETV3 wt Allele, Obesity | Altered Intercellular Communication | The impact of obesity on an individual's quality of life is enhanced by grade of obesity, T2D, MetS and inflammation and are mainly related to reduced physical health. | 26474291 |
| Inflammation, Pancreatic carcinoma | Altered Intercellular Communication | Impact of Intratumoral Inflammation on Survival After Pancreatic Cancer Resection. | 26474423 |
| Cessation of life, Inflammation, Neoplasms | Altered Intercellular Communication | We sought to evaluate whether inflammation in the primary tumor was associated with early death after surgical resection. | 26474423 |
| Inflammation, Neoplasms | Altered Intercellular Communication | Future studies evaluating the host response in multiple tumor compartments with advanced histologic techniques is needed to further elucidate the role of inflammation in PaC. | 26474423 |
| methyldopa, Retinitis | Altered Intercellular Communication | Wnt signaling may be disturbed in AMD patients, which could contribute to the retinal inflammation and increased A2E levels found in AMD. | 26476672 |
| Electrocardiogram: myocardial infarction (finding) | Altered Intercellular Communication | Complement activation contributes significantly to inflammation-related damage in the heart after acute myocardial infarction. | 26476955 |
| Inflammation, Exophthalmos | Altered Intercellular Communication | His right eye showed exophthalmos, inflammation in the anterior chamber and iris neovascularization. | 26477069 |
| Inflammation, Cardiac sarcoidosis | Altered Intercellular Communication | The present study investigated whether (18)F-fluorodeoxyglucose-positron emission tomography (FDG-PET) uptake as an index of active inflammation in patients with cardiac sarcoidosis (CS) is associated with BMIPP and TL findings, and whether dual single-photon emission computed tomography (SPECT) can facilitate diagnosis of CS. | 26477356 |
| Inflammation, Hemophilic arthropathy | Altered Intercellular Communication | Inflammation and degeneration play roles in the pathogenesis of hemophilic arthropathy. | 26479992 |
| Sleeplessness | Altered Intercellular Communication | [Expressions of neurotransmitters in patients of insomnia differentiated as liver stagnation transforming into fire treated with acupuncture]. | 26480548 |
| Inflammation, Anemia | Altered Intercellular Communication | Children living with HIV in India have a high prevalence of anemia mediated by iron deficiency, vitamin A deficiency and chronic inflammation. | 26482352 |
| Inflammation, Facial edema, Granuloma | Altered Intercellular Communication | Axial computed tomography (CT) scan of the paranasal sinuses showed a clear left facial swelling chronic inflammation and granulomata. | 26482354 |
| Inflammation, Obesity | Altered Intercellular Communication | These observations and the increasing global prevalence of obesity justify ongoing efforts to understand the role of obesity-induced inflammation in the pathogenesis and management of AP. | 26482857 |
| Inflammation | Altered Intercellular Communication | Inflammation resulted in the reduced colonic expression of ERBB2, GRB7, MIEN1, and PGAP3 (P = 1.0 x 10(-4)-1.0 x 10(-9)) and the increased colonic expression of IKZF3 and CSF3 (P = 2.4 x 10(-7)-3.5 x 10(-8)). | 26484354 |
| HD Term Type, Inflammation | Altered Intercellular Communication | Increased LIAT and inflammation were found to be closely associated with 2 years combined CV events and all-cause mortality in HD patients. | 26484658 |
| Gastrointestinal inflammation, Intestinal Diseases, Enterocytes | Altered Intercellular Communication | This study demonstrated enterocyte damage and intestinal inflammation in CF patients, and provides evidence for an inverse correlation between enteropathy and lung function. | 26484665 |
| vascular inflammations, Atherosclerosis | Altered Intercellular Communication | Increased MIF plasma levels promote vascular inflammation and development of atherosclerosis. | 26485680 |
| Proteinuria | Altered Intercellular Communication | TLR2-MyD88-NF-kB pathway is involved in tubulointerstitial inflammation caused by proteinuria. | 26485683 |
| Proteinuria | Altered Intercellular Communication | Several studies have suggested that proteinuria initiates tubulointerstitial inflammation, while the mechanisms have not been fully understood. | 26485683 |
| Proteinuria | Altered Intercellular Communication | In this study, we hypothesized whether the activation of the TLR2-MyD88-NF-kB pathway is involved in tubulointerstitial inflammation induced by proteinuria. | 26485683 |
| Proteinuria, Moist | Altered Intercellular Communication | In summary, we demonstrated that proteinuria may exhibit an endogenous danger-associated molecular pattern (DAMP) that induces tubulointerstitial inflammation via the TLR2-MyD88-NF-kB pathway activation. | 26485683 |
| Inflammation | Altered Intercellular Communication | However, the connection between this lysosomal storage and inflammation is not clear. | 26486234 |
| Parkinson Disease, Inflammation | Altered Intercellular Communication | Moreover, this link between lysosomal storage, impaired autophagy, and inflammation may have implications relevant to both Parkinson disease and the aging process. | 26486234 |
| Cholecystitis, Acute Cholecystitis | Altered Intercellular Communication | Does the Tokyo guidelines predict the extent of gallbladder inflammation in patients with acute cholecystitis? | 26486453 |
| Inflammation | Altered Intercellular Communication | The preoperative severity grades were compared with the histological extent of inflammation. | 26486453 |
| Cholecystitis | Altered Intercellular Communication | 43, p = 0.01) between the preoperative severity grade and the extent of gallbladder inflammation on histopathology. | 26486453 |
| Inflammation | Altered Intercellular Communication | However, the Tokyo guidelines may have a tendency to underestimate the extent of inflammation in male patients with severity grade I and over estimate the difficulty of dissection in severity grade II. | 26486453 |
| Inflammation, Fibrosis Assessment, Neoplasms | Altered Intercellular Communication | Accuracy of T-staging was significantly worse after CRT (0.16) than after CT (0.43), obviously due to difficulty in distinguishing residual tumor from treatment-associated fibrosis and inflammation. | 26487231 |
| Proteinuria, Inflammation, Kidney Failure, Chronic Kidney Diseases | Altered Intercellular Communication | Lact supplementation mitigated the systemic inflammation and proteinuria associated with renal failure, suggesting that in the gut microbiota, Lact plays a protective role against the progression of CKD. | 26487672 |
| Inflammation | Altered Intercellular Communication | It aids in delineating severe inflammation requiring surgery without substantial delay. | 26488396 |
| Airway structure, Tissue damage | Altered Intercellular Communication | Asthma is characterized by airway inflammation, and bronchial airways are particularly susceptible to oxidant-induced tissue damage. | 26490046 |
| Inflammation, Cholesteatoma | Altered Intercellular Communication | It might suggest that the higher the expression of MMP-9 the stronger the inflammation -accompanied cholesteatoma. | 26490574 |
| Inflammation, Neoplasms, Malignant Neoplasms | Altered Intercellular Communication | Inflammation and tumor immune microenviroment are critical factors for prognosis in numerous cancers. | 26490984 |
| Inflammation, Disease | Altered Intercellular Communication | The CFs from a published meta-analysis were appropriate for use in this population with a high prevalence of Hb disorders and inflammation. | 26491125 |
| Renal Insufficiency, Inflammation | Altered Intercellular Communication | Significance of Neutrophil Gelatinase-Associated Lipocalin Level-to-Serum Creatinine Ratio for Assessing Severity of Inflammation in Patients with Renal Dysfunction. | 26491688 |
| Renal Insufficiency, Inflammation | Altered Intercellular Communication | In short, the NGAL/sCr ratio may offer useful information when screening patients with both systemic inflammation and renal dysfunction. | 26491688 |
| Inflammation, Calcinosis | Altered Intercellular Communication | Tissue sections were stained with hematoxylin and eosin, Masson trichrome, and Movat pentachrome, and were graded for inflammation, tissue substitute degeneration, neointima formation, and calcification. | 26492092 |
| Inflammation | Altered Intercellular Communication | Inflammation and tissue degeneration were greater in PhotoFix pericardium compared to autologous pericardium but were no more than moderate. | 26492092 |
| Inflammation, Calcinosis, Abnormal degeneration | Altered Intercellular Communication | PhotoFix bovine pericardium is associated with more inflammation and material degeneration but calcification, and neointima formation are similar to autologous pericardium. | 26492092 |
| Coinfection, Inflammation, Ear Inflammation | Altered Intercellular Communication | External otitis is a diffuse inflammation around the external auditory canal and auricle, which is often occurred by microbial infection. | 26492256 |
| Inflammation, Metabolic Syndrome X, Carotid Intima-Media Thickness | Altered Intercellular Communication | Childhood metabolic syndrome, inflammation and carotid intima-media thickness. | 26492305 |
| Inflammation, ETV3 wt Allele, Atherosclerosis | Altered Intercellular Communication | MetS in childhood is associated with subclinical atherosclerosis in an Australian Aboriginal population and the effects appear to be mediated by increased inflammation. | 26492305 |
| Inflammation, Nasal Polyps, Chronic sinusitis | Altered Intercellular Communication | Chronic rhinosinusitis with nasal polyps (CRSwNP) is associated with Th2-dominant inflammation. | 26492334 |
| Parkinson Disease, Inflammation, Diabetes Mellitus, Non-Insulin-Dependent | Altered Intercellular Communication | Thiazolidinediones, a class of medications indicated for the treatment of type 2 diabetes mellitus, reduce inflammation and have been shown to provide a therapeutic benefit in animal models of Parkinson disease. | 26493264 |
| Inflammation, Neoplasms | Altered Intercellular Communication | NLR may reflect host immunity and systemic inflammation that facilitates tumor growth. | 26493696 |
| palladium, Vascular Diseases, Inflammation | Altered Intercellular Communication | We evaluated circulating S100A12 and sRAGE in relation to vascular disease, inflammation, nutritional status, and mortality risk in peritoneal dialysis (PD) patients. | 26493750 |
| palladium, Inflammation, Vascular Diseases | Altered Intercellular Communication | Soluble RAGE was inversely related to body mass indices while S100A12 associated with increased inflammation, PCVD, and mortality, suggesting that S100A12 may identify PD patients at high risk for vascular disease and increased mortality. | 26493750 |
| Primary malignant neoplasm | Altered Intercellular Communication | Incidental adrenal masses detected in the presence history of cancer should always be subjected to hormonal evaluation. | 26494041 |
| Inflammation, atherosclerotic | Altered Intercellular Communication | Rather, g' fibrinogen concentrations seem to reflect general inflammation that accompanies and may contribute to atherosclerotic CVD, instead of g' fibrinogen being a causal risk factor. | 26494231 |
| Sepsis, Inflammation, Observation Method - Coagulation, Communicable Diseases | Altered Intercellular Communication | Sepsis is characterized by systemic activation of inflammation and coagulation in response to infection. | 26494232 |
| Inflammation, hepcidin, Anemia | Altered Intercellular Communication | Hepcidin-25 production is stimulated by systemic inflammation, and it interferes with iron utilization, leading to anemia. | 26496240 |
| Inflammation, Hemorrhage, Neoplasms, Hookworm Infections, Lymphoma, Ulcer, Vascular anomaly, Crohn Disease | Altered Intercellular Communication | Patients who underwent single-balloon enteroscopy were found to have neoplasms (most common age group: 14-45 years, most common lesion location: jejunum), lymphoma (46-59 and 60-74 years, ileum), protuberant lesions (45-59 years, jejunum), inflammation (14-45 and 46-59 years, ileum), benign ulcers (14-45 years, jejunum), diverticulum (14-45 years, ileum), vascular malformations (60-74 years, jejunum), polyps (14-45 years, jejunum), Crohn's disease (14-45 years, jejunum), hookworm infection (14-45 years, jejunum), lipid pigmentation (14-45 and 46-59 years, jejunum), undetermined bleeding (46-59 years, ileum), or undetermined stenosis (31 years, duodenum). | 26496270 |
| Cessation of life, Inflammation, Malnutrition | Altered Intercellular Communication | The mortality rates and causes of death were analyzed.The analytic results demonstrated patients in the high BCL group had a significantly higher prevalence of malnutrition and inflammation than patients in the low and intermediate BCL groups. | 26496294 |
| Cancer of Urinary Tract, Inflammation | Altered Intercellular Communication | Recently, many studies explored the role of inflammation parameters in the prognosis of urinary cancers, but the results were not consistent. | 26496339 |
| Inflammation, Malignant Neoplasms | Altered Intercellular Communication | The modified Glasgow Prognostic Score (mGPS), a systemic inflammation marker, is a prognostic marker in various types of cancers. | 26496339 |
| Inflammation | Altered Intercellular Communication | An MRI score >= 4 indicated the best results, with sensitivity of 86%, specificity of 79%, positive predictive value of 80%, negative predictive value of 85%, and accuracy of 82% for pouch inflammation. | 26496569 |
| Inflammation | Altered Intercellular Communication | In patients who have undergone IPAA surgery, the MRE findings strongly correlate with the pouch endoscopic findings with high sensitivity and positive predictive value for pouch inflammation. | 26496569 |
| Inflammation, Hemorrhage, Vasculitis, CTCAE | Altered Intercellular Communication | The four subjects had manifestations of vasculitis including hemorrhage within the cochlea and vestibule, and inflammation and occlusion of vessels in the lateral cochlear wall and the vasa nervorum of the facial nerve. | 26496669 |
| Inflammation, Brain Injuries, Postoperative cognitive dysfunction | Altered Intercellular Communication | Postoperative cognitive dysfunction after inhalational anesthesia in elderly patients undergoing major surgery: the influence of anesthetic technique, cerebral injury and systemic inflammation. | 26497059 |
| Inflammatory Bowel Diseases, Inflammation | Altered Intercellular Communication | Estrogens have a complex role in inflammation and growing evidence suggests that these hormones may impact IBD pathogenesis. | 26497217 |
| Inflammatory Bowel Diseases, Inflammation | Altered Intercellular Communication | Estrogens have a complex role in inflammation and growing evidence suggests that these hormones may impact IBD pathogenesis. | 26497217 |
| Inflammation, Damage, Muscular Atrophy | Altered Intercellular Communication | Muscle atrophy results from a range of physiological conditions, including immobilization, spinal cord damage, inflammation and aging. | 26497270 |
| Degenerative polyarthritis, Inflammation | Altered Intercellular Communication | Synovial angiogenesis and inflammation are observed across the full range of OA severity. | 26497299 |
| Communicable Diseases, Inflammation | Altered Intercellular Communication | C-reactive protein (CRP) is a common marker of acute or chronic inflammation and infection. | 26497919 |
| Inflammation, Pain, Postoperative | Altered Intercellular Communication | The new robotic single-site platform might offer potential benefits on local inflammation and postoperative pain due to its technological advantages. | 26497946 |
| Myocarditis | Altered Intercellular Communication | Immunohistological examination revealed myocardial inflammation in 2 individuals (4%). | 26498214 |
| ARCN1 gene, Inflammation | Altered Intercellular Communication | Alternative treatment options such as combined theophylline with low-dose CsA, that inhibit these pro-inflammatory cells, may reduce systemic inflammation in COPD. | 26498345 |
| Inflammation, Squamous cell carcinoma of vulva | Altered Intercellular Communication | Chronic inflammation induced by lichen sclerosus (LS) or human papilloma virus (HPV) precedes vulvar squamous cell carcinoma (vulvar SCC). | 26499936 |
| Autoimmune Diseases, Inflammation, Cerebral Atherosclerosis, Atherosclerosis | Altered Intercellular Communication | Higher circulating anti-Hsp60 is associated with advanced cerebrovascular atherosclerosis as a consequence of the autoimmunity part of the inflammation and bursting of atherosclerosis. | 26500006 |
| Pancreatic carcinoma | Altered Intercellular Communication | Prognostication by inflammation-based score in patients with locally advanced pancreatic cancer treated with chemoradiotherapy. | 26500167 |
| Inflammation, Hypoxemia | Altered Intercellular Communication | Results Even though patients exhibited systemic inflammation and anemic hypoxemia, dCA was similar to healthy volunteers (gain: 1.24 [0.94-1.49] vs. 1.22 [1.06-1.34] cm mm Hg-1 s-1, p = 0.97; phase: 0.33 [0.15-0.56] vs. 0.69 [0.50-0.77] rad, p = 0.09). | 26501221 |
| Inflammation, Surgical incisions, Acute onset pain | Altered Intercellular Communication | Persistent incisional pain is common after cardiac surgery and is believed to be in part related to inflammation and poorly controlled acute pain. | 26501386 |
| Inflammation, Aortic Aneurysm, Abdominal | Altered Intercellular Communication | Abdominal aortic aneurysms are associated with chronic inflammation within the aortic wall, and previous studies have suggested that chronic inflammation may be a consequence of a dysregulated and persistent autoimmune response. | 26501863 |
| Inflammation, Postoperative Complications, GDC Comorbidity Terminology | Altered Intercellular Communication | These patients had similar comorbid conditions compared with patients without inflammation but significantly greater numbers of major postoperative complications after EVAR (23.5% vs 3.6%; P = .02) and overall postoperative complications after EVAR (27.5% vs 7.1%; P = .03). | 26501863 |
| Inflammatory abnormality of the eye, Vitreous strands | Altered Intercellular Communication | Scores obtained using the VHRF algorithm may be obtained from OCT images that include the vitreous and could provide a rapid, noninvasive clinical correlate for ocular inflammation. | 26502148 |
| Autoimmune Diseases, Myocarditis | Altered Intercellular Communication | In addition, the association of LVDD with myositis-specific or -associated autoantibodies and high cardiac (99m) Tc-PYP uptake supports the notion of underlying autoimmunity and myocardial inflammation in patients with PM/DM. | 26502301 |
| Inflammation, Malignant Neoplasms | Altered Intercellular Communication | Cancer-related inflammation affects many aspects of malignancy, including proliferation and survival of malignant cells, angiogenesis, and therapeutic response. | 26502851 |
| Inflammation, Primary malignant neoplasm | Altered Intercellular Communication | Some biomarkers representing the degree of systemic inflammation, such as the Glasgow prognostic score, NLR and PLR, have been shown to have prognostic value in many kinds of cancer patients. | 26502851 |
| Inflammation, Chronic disease | Altered Intercellular Communication | The red cell distribution width-platelet ratio (RPR), a novel inflammatory marker is currently used to predict inflammation in chronic diseases. | 26503078 |
| Inflammation, Carcinogenesis | Altered Intercellular Communication | As inflammation and androgen pathways are implicated in prostate carcinogenesis, additional studies of anti-inflammatory medications in relation to these PCa subtypes are warranted. | 26503111 |
| Inflammation | Altered Intercellular Communication | Such changes in other brain structures may explain gliosis, dendritic volume increase, or inflammation. | 26503297 |
| Acute inflammation | Altered Intercellular Communication | Patients undergoing lung resection and one-lung ventilation exhibited significant postoperative inflammation and oxidative damage. | 26503312 |
| Pneumonitis | Altered Intercellular Communication | Preoperative administration of N-acetylcysteine did not attenuate postoperative systemic or pulmonary inflammation or oxidative damage after lung resection. | 26503312 |
| Inflammation, Primary malignant neoplasm, Neoplasms | Altered Intercellular Communication | Inflammation is a hallmark of cancer, yet the mechanisms that regulate immune cell infiltration into tumors remain poorly characterized. | 26503598 |
| Inflammation, Neoplasms | Altered Intercellular Communication | However, because the passive accumulation of ICG could not be used to discriminate tumours with inflammation, tumour-targeted fluorescence should be developed to solve this problem in the future. | 26503731 |
| Inflammation, Eosinophilic esophagitis, Immune-mediated | Altered Intercellular Communication | Eosinophilic esophagitis is an immune-mediated disease resulting in inflammation of the esophagus. | 26505065 |
| Inflammation, Metabolic Syndrome X, Cardiovascular Diseases, ETV3 wt Allele, Diabetes Mellitus | Altered Intercellular Communication | Metabolic syndrome (MetS) predisposes to both diabetes and cardiovascular disease, and inflammation is pivotal in MetS. | 26505293 |
| osteitis pubis, Inflammation | Altered Intercellular Communication | Osteitis pubis or symphysitis pubis is a rare occurring non-infectious inflammation of the symphysis, the adjacent pubic bones and surrounding tissue. | 26506827 |
| Inflammation, Malignant neoplasm of endometrium | Altered Intercellular Communication | The relation between inflammation deriving from diet and endometrial cancer risk has not yet been investigated. | 26507451 |
| Inflammation, Lymphovascular | Altered Intercellular Communication | Delay in diagnosis, depth of invasion, marked inflammation, lymphovascular invasion, and regional lymph node status are important prognostic factors. | 26508372 |
| Inflammation, Progranulins | Altered Intercellular Communication | Whereas resistin represents a systemic marker of inflammation, CSF progranulin levels strongly depend on the underlying disease and dysfunction of blood-CSF barrier. | 26509463 |
| Inflammation, Communicable Diseases, Granulation finding, Scab, Mucous membrane edema | Altered Intercellular Communication | Objective data was obtained by blinded endoscopic scoring to rate mucosal edema, inflammation, granulation, crusting, infection, and synechiae formation on postoperative weeks 1, 3, and 6. | 26509639 |
| Scab, Inflammation | Altered Intercellular Communication | In objective measures, CMC gel nearly reaches significance for more postoperative debridement, with increased crusting and inflammation. | 26509639 |
| Crohn Disease, Abdominal symptom | Altered Intercellular Communication | Inflammation-related enteric dysmotility has been postulated as a cause for abdominal symptoms in Crohn's disease (CD). | 26509756 |
| Abdominal symptom | Altered Intercellular Communication | Reduced motility variance in morphologically normal SB is associated with patient symptoms and fecal calprotectin levels, supporting the hypothesis that inflammation-related enteric dysmotility may explain refractory abdominal symptoms in CD. | 26509756 |
| Inflammation, Data types - Address | Altered Intercellular Communication | We therefore conclude that S. aureus may cause and promote inflammation in the skin of AD children through concomitant Th2 activation and the silencing of resident Treg cells. | 26510097 |
| Inflammation, Lung Diseases, Interstitial, Fibrosis Assessment | Altered Intercellular Communication | Interstitial lung disease (ILD) includes a diverse group of respiratory conditions characterised by inflammation and fibrosis of the interstitium. | 26510140 |
| palladium, Inflammation | Altered Intercellular Communication | Incident PD patients treated with low GDP solution have less severe systemic inflammation but trends of less ultrafiltration, and more fluid accumulation. | 26510186 |
| Necrotizing granulomatous inflammation, Squamous cell carcinoma | Altered Intercellular Communication | Histological examination of a mass of few fused lymph nodes, isolated from left laterocervical lymphadenectomy, showed metastatic squamous cell carcinoma with concomitant granulomatous inflammation. | 26510425 |
| Inflammation, Neurogenic Inflammation, "Alzheimers Disease | Altered Intercellular Communication | Voxel-wise correlation analysis suggests that neuroinflammation is associated with localized amyloid deposition and glucose metabolism over time, however, the level of inflammation could also occur independently of amyloid pathology, especially in the later stages of Alzheimer's disease. | 26510952 |
| Inflammation, Ischemia, Guillain-Barre Syndrome, Familial, Acute Infective Polyneuritis | Altered Intercellular Communication | Both chronic inflammation and nerve ischaemia in DM may intervene in the disease course of GBS, which is a prototype of acute inflammatory neuropathy. | 26511168 |
| ARCN1 gene, Inflammation | Altered Intercellular Communication | As C/EBPb exerts pro-inflammatory effects in the context of cigarette smoke, the elevated C/EBPb in advanced COPD may be an indication of a breakdown of regulatory mechanisms and excessive inflammation. | 26511475 |
| Intraocular inflammation | Altered Intercellular Communication | A 78-year-old, immunocompetent woman presented with subacute intraocular inflammation with high intraocular pressure, mimicking phacolytic glaucoma. | 26511718 |
| Cataract, Inflammation | Altered Intercellular Communication | Even though the cataract extraction was uneventful and adequate anti-inflammatory drugs were given, the inflammation did not subside as expected. | 26511718 |
| Inflammation, Cyclophosphamide/Vincristine/Dacarbazine Regimen, Obesity, Cardiovascular Diseases | Altered Intercellular Communication | Obesity may contribute to cardiovascular disease (CVD) risk by eliciting chronic systemic inflammation and impairing the immune response to additional stressors. | 26511907 |
| Orbital Pseudotumor | Altered Intercellular Communication | Patients who were diagnosed with AAPOX at a French academic referral center for orbital inflammation between November 1996 and March 2013 were enrolled. | 26512617 |
| Acute Kidney Injury, CTCAE, Inflammation | Altered Intercellular Communication | Additional blood test showed inflammation and acute kidney injury Rifle category failure. | 26512791 |
| Granulomatous inflammation | Altered Intercellular Communication | A skin and kidney biopsy indicated a granulomatous inflammation. | 26512791 |
| Granulomatous inflammation | Altered Intercellular Communication | A complete workup for other causes of granulomatous inflammation was negative. | 26512791 |
| Inflammation, Primary malignant neoplasm, Electrocardiogram: myocardial infarction (finding) | Altered Intercellular Communication | The association between number of teeth and low-grade systemic inflammation deserves consideration within the European Prospective Investigation into Cancer and Nutrition (EPIC)-Potsdam since the association between number of teeth and myocardial infarction has been established. | 26513265 |
| Inflammation, Electrocardiogram: myocardial infarction (finding) | Altered Intercellular Communication | This study shows that number of teeth has a weak association with hsCRP, if any, thereby excluding this marker of low-grade systemic inflammation as a possible explanation for the association between number of teeth and myocardial infarction. | 26513265 |
| Inflammation, Fibrosis Assessment, Non-alcoholic Fatty Liver Disease | Altered Intercellular Communication | In NAFLD, serum b-trophin was related to liver fibrosis and inflammation. | 26513612 |
| Sepsis, Blood Coagulation Disorders | Altered Intercellular Communication | Sepsis is invariably accompanied by altered coagulation cascade; however, the precise role of phosphatidylserine (PS) in inflammation-associated coagulopathy in sepsis has not been well elucidated. | 26513704 |
| Inflammation, Gastrointestinal Neoplasms | Altered Intercellular Communication | Inflammation plays a major role in the development and progression of gastric and other gastrointestinal tumors. | 26514504 |
| Inflammation, Observation Method - Coagulation, Myocardial dysfunction, Immune dysregulation, Renal Insufficiency | Altered Intercellular Communication | In addition, blood markers potentially linked to frailty and related to the processes of inflammation, coagulation, hormonal dysregulation, nutrition, renal dysfunction, and heart dysfunction were determined. | 26514748 |
| Inflammation, Observation Method - Coagulation, Myocardial dysfunction, Immune dysregulation, Renal Insufficiency | Altered Intercellular Communication | In addition, blood markers potentially linked to frailty and related to the processes of inflammation, coagulation, hormonal dysregulation, nutrition, renal dysfunction, and heart dysfunction were determined. | 26514748 |
| Inflammation, Malignant Head and Neck Neoplasm, Fatigue | Altered Intercellular Communication | Fatigue is associated with inflammation in patients with head and neck cancer before and after intensity-modulated radiation therapy. | 26515035 |
| Inflammation, Primary malignant neoplasm, Fatigue | Altered Intercellular Communication | Although inflammation has been proposed as one of the potential mechanisms of fatigue in cancer patients, findings have not been consistent, and there is a dearth of longitudinal studies. | 26515035 |
| Inflammation, Fatigue, MMP8 wt Allele | Altered Intercellular Communication | In conclusion, our findings support the hypotheses that inflammation is associated with fatigue over time in HNC patients. | 26515035 |
| Inflammation, Fatigue | Altered Intercellular Communication | Future studies on how inflammation contributes to fatigue as well as strategies targeting inflammation to reduce fatigue are warranted. | 26515035 |
| Inflammation, Metabolic Syndrome X, Atherosclerosis | Altered Intercellular Communication | There is a widely approved influence of novel risk factors like the body fat distribution and the associated metabolic syndrome, subclinical inflammation, insulin resistance and prediabetic disturbances in glucose metabolism on the progression of atherosclerosis. | 26515221 |
| Inflammation | Altered Intercellular Communication | Inflammation induced by HBV infection presented a positive association with HPCs activation (P < 0.05). | 26515593 |
| Presenile dementia, Dementia, Vascular, VAD I protocol | Altered Intercellular Communication | Conversely, the involvement of central cholinergic neurotransmission in vascular dementia (VaD) is still under debate and data on Vascular Cognitive Impairment--No Dementia (VCI-ND) at risk for future VaD are lacking. | 26515786 |
| Gingivitis, Necrosis, Bothered by Vomiting, Diarrhea, Ulcer, Dental Plaque | Altered Intercellular Communication | As well as diarrhoea and vomiting, she had a very aggressive gingival inflammation with multiple ulcerations in both jaws and wide areas of necrotic bone, affecting the attached gingiva, and seemingly unrelated to dental plaque. | 26516027 |
| Inflammation, Infiltration, Monocytosis | Altered Intercellular Communication | Angiotensin II-infused Hmox1-/- mice had amplified endothelial inflammation in vivo, significantly increased aortic infiltration of pro-inflammatory CD11b+ Ly6C(hi) monocytes and Ly6G+ neutrophils and were marked by Ly6C(hi) monocytosis in the circulation and an increased blood pressure response. | 26516175 |
| Cushing Syndrome, hypothalamic-pituitary-adrenal axis | Altered Intercellular Communication | Hormonal assays were compatible with hypothalamic-pituitary-adrenal axis suppression, and iatrogenic Cushing's syndrome due to ritonavir-fluticasone interaction was considered. | 26516245 |
| Communicable Diseases, Inflammation | Altered Intercellular Communication | suspected infection, 2 or more criteria for systemic inflammation, and either systolic blood pressure <90 mmHg after a fluid bolus or lactate >4 mmol/liter. | 26517062 |
| ARCN1 gene, Inflammation, Exacerbation, Virus Diseases, Immune System Diseases | Altered Intercellular Communication | This study has established a signal of cytotoxic immune dysfunction and aberrant immune regulation in the COPD lung that may explain both the susceptibility to viral infection and the excessive inflammation associated with exacerbations. | 26517304 |
| Traumatic injury | Altered Intercellular Communication | Twenty-eight-day longitudinal HDAC leukocyte gene expression profiles in 172 blunt trauma patients were extracted from the Inflammation and the Host Response to Injury (Glue Grant) data set. | 26517778 |
| Waldenstrom Macroglobulinemia, Fibrosis Assessment | Altered Intercellular Communication | Histopathologic examination revealed marked lymphoplasmacytic inflammation and inter-lobular fibrosis, which were more severe in the superficial than deep portion of the affected glands. | 26518180 |
| N-formyl-13-dihydrocarminomycin, Inflammation | Altered Intercellular Communication | However, there are significant caveats associated with the idea that inflammation directly causes either a-synuclein pathology or neurofibrillary degeneration (NFD). | 26518296 |
| Inflammation | Altered Intercellular Communication | Telomerase Deficiency Causes Alveolar Stem Cell Senescence-associated Low-grade Inflammation in Lungs. | 26518879 |
| deficiency aspects, Inflammation | Altered Intercellular Communication | Our data demonstrate for the first time that telomerase deficiency triggers alveolar stem cell replicative senescence-associated low-grade inflammation, thereby driving pulmonary premature aging, alveolar sac formation, and fibrotic lesion. | 26518879 |
| Inflammation, Data types - Address, physiopathological | Altered Intercellular Communication | Most processes associated with AD pathogenesis, such as inflammation, synaptic dysfunction, and hyper-phosphorylation of tau are dependent on protein kinase activity. | 26519433 |
| Inflammation, Acute-On-Chronic Liver Failure | Altered Intercellular Communication | Treatment with non-selective beta blockers is associated with reduced severity of systemic inflammation and improved survival of patients with acute-on-chronic liver failure. | 26519600 |
| Inflammation, Acute-On-Chronic Liver Failure, CRNKL1 wt Allele | Altered Intercellular Communication | Acute-on-chronic liver failure (ACLF) is characterized by systemic inflammation and high mortality. | 26519600 |
| Inflammation, Cardiovascular Diseases | Altered Intercellular Communication | Haemodialysis patients suffer from chronic systemic inflammation and high incidence of cardiovascular disease. | 26519693 |
| Diabetes Mellitus, Non-Insulin-Dependent, Inflammation, Cyclophosphamide/Vincristine/Dacarbazine Regimen, Cardiovascular Diseases | Altered Intercellular Communication | Prediabetes is associated with low-grade chronic inflammation that increases the risk for developing type 2 diabetes (T2D) and cardiovascular disease (CVD). | 26520413 |
| Inflammation, physiopathological | Altered Intercellular Communication | Selective modulation of the intestinal microbiota with prebiotics reduces intestinal permeability and endotoxin concentrations, inflammation, and metabolic dysfunction in rodents. | 26520413 |
| Tissue damage, Inflammation | Altered Intercellular Communication | Chemokines and cytokines play a pivotal role in the regulation of mucosal inflammation by promoting leukocyte migration to sites of inflammation ultimately leading to tissue damage and destruction. | 26520877 |
| Tissue damage, Gastrointestinal inflammation, Inflammatory Bowel Diseases | Altered Intercellular Communication | These data clearly indicate an increase in circulating levels of specific chemokines and cytokines that are known to modulate systemic level through immune cells results in affecting local intestinal inflammation and tissue damage in IBD patients. | 26520877 |
| Inflammation, Metabolic Syndrome X, Bipolar Disorder | Altered Intercellular Communication | Low physical activity, inflammation, metabolic syndrome and vascular risk factors were associated with elevated depressive symptoms. | 26521086 |
| Inflammation, Impaired cognition, Diabetes Mellitus, Bipolar Disorder, Hypertension, CTCAE | Altered Intercellular Communication | Low physical activity (z=2.16, p=0.03) and inflammation (z=2.3, p=0.02) mediated the relationship between depressive symptoms and cognitive decline while hypertension, diabetes and smoking also contributed. | 26521086 |
| Inflammation, Impaired cognition, Bipolar Disorder | Altered Intercellular Communication | The relationship between depressive symptoms and cognitive decline in later life appears to be mediated by low physical activity, increased inflammation and vascular risk factors that may be amenable to modification. | 26521086 |
| Degenerative polyarthritis, Inflammation | Altered Intercellular Communication | This study will help identify new therapeutic strategies for OA, especially the targeting of IL-22 to decrease inflammation. | 26521730 |
| Degenerative polyarthritis, Inflammation | Altered Intercellular Communication | Associations of markers of matrix metabolism, inflammation markers, and adipokines with superior cam deformity of the hip and their relation with future hip osteoarthritis. | 26521735 |
| Rotator cuff syndrome, Inflammation, Congenital Abnormality | Altered Intercellular Communication | Some markers of inflammation (pLeptin, pAdiponectin, and erythrocyte sedimentation rate) were lower in presence of cam deformity and cam impingement, but high-sensitivity C-reactive protein was not. | 26521735 |
| Rotator cuff syndrome, Inflammation, Congenital Abnormality | Altered Intercellular Communication | Subjects with cam deformity and cam impingement surprisingly showed lower levels of inflammation markers and adipokines. | 26521735 |
| Degenerative polyarthritis, Inflammation, Erosion lesion | Altered Intercellular Communication | Ultrasound detected inflammation is associated with the development of new bone erosions in hand osteoarthritis: a longitudinal study over 3.9 years. | 26521738 |
| Degenerative polyarthritis, Inflammation, Erosion lesion, 4-hydroxy-2-oxovalerate aldolase activity | Altered Intercellular Communication | To evaluate the association between ultrasound (US) detected inflammation at baseline and the subsequent development of new bone erosions at follow-up in patients with hand osteoarthritis (HOA). | 26521738 |
| Inflammation | Altered Intercellular Communication | US detected synovial inflammation features were scored as present/absent. | 26521738 |
| Inflammation, Erosion lesion | Altered Intercellular Communication | Synovial inflammation as detected by PDS was associated with the appearance of new bone erosions. | 26521738 |
| Degenerative polyarthritis, Inflammation | Altered Intercellular Communication | Inflammation plays a major role in OA, particularly through the cytokine Interleukine-1b, promoting reactive oxygen species (ROS) generation and matrix metalloproteinases (MMP) synthesis by the chondrocytes, orchestrating matrix proteolysis. | 26521743 |
| Inflammation | Altered Intercellular Communication | Taken together, we propose that SIRT1 forms an anti-inflammatory complex with HMGB1, allowing cells to bypass the response to inflammation. | 26522327 |
| Inflammation, Squamous cell carcinoma | Altered Intercellular Communication | The association and prognostic relevance of cancerous inhibitor of protein phosphatase 2A and inflammation in tongue squamous cell carcinoma. | 26522733 |
| Inflammation, Primary malignant neoplasm, Hyperplasia | Altered Intercellular Communication | CIP2A was similarly detected in tongue cancer and tongue hyperplasia, whereas local inflammation was stronger in cancer (p = 0.000). | 26522733 |
| Inflammation, Primary malignant neoplasm | Altered Intercellular Communication | Cancer patients aged >=60 with increased inflammation predicted poor survival (p = 0.037). | 26522733 |
| Inflammation, Primary malignant neoplasm | Altered Intercellular Communication | CIP2A and inflammation might play a role in progression of tongue cancer. | 26522733 |
| Inflammation | Altered Intercellular Communication | Inflammation is a common link between metabolic dysregulation and aging. | 26522807 |
| allergic inflammation, Helminths | Altered Intercellular Communication | The Intestinal Microbiota Contributes to the Ability of Helminths to Modulate Allergic Inflammation. | 26522986 |
| Synovitis, Edema, Erosion of bone, Orchitis, Tenosynovitis | Altered Intercellular Communication | Images were scored blindly twice by 3 independent readers according to the PsAMRIS (for synovitis, tenosynovitis, periarticular inflammation, bone edema, bone erosion, and bone proliferation). | 26523032 |
| Orchitis, Tenosynovitis | Altered Intercellular Communication | Baseline interreader ICC were good (ICC 0.72-0.96) for all features, except periarticular inflammation and bone proliferation in the hand and tenosynovitis in the foot (ICC 0.25-0.44). | 26523032 |
| Parkinson Disease, palladium, MULTISYSTEM DISORDER | Altered Intercellular Communication | Parkinson's disease (PD) is a multisystem disorder, involving several monoaminergic neurotransmitter systems resulting in a broad range of motor and non-motor symptoms. | 26523794 |
| Postprandial Period, Chylomicrons | Altered Intercellular Communication | In vivo evidence for chylomicrons as mediators of postprandial inflammation. | 26523991 |
| Postprandial Period | Altered Intercellular Communication | The postprandial chylomicron response may be a stronger mediator of postprandial inflammation than postprandial triglyceridemia. | 26523991 |
| Atherosclerosis | Altered Intercellular Communication | The postprandial situation is a pro-inflammatory condition most likely linked to the development of atherosclerosis. | 26523991 |
| Inflammation, Asthma, AHR wt Allele | Altered Intercellular Communication | This study aims to determine whether in utero ETS exposure alters DNA methylation patterns and increases airway hyperreactivity (AHR) and inflammation. | 26525176 |
| AHR wt Allele, Pneumonitis | Altered Intercellular Communication | Collectively, these data suggest that in utero ETS exposure increases the risk of pulmonary inflammation and AHR through altered DNA methylation, but additional studies are needed to fully determine the causal link between changes in methylation and cytokines levels, as well as AHR. | 26525176 |
| Inflammation | Altered Intercellular Communication | Post-cardiac arrest syndrome (PCAS) is characterized by systemic inflammation, however data on the prognostic value of inflammatory markers is sparse. | 26525271 |
| Cardiac Arrest, Inflammation, Comatose | Altered Intercellular Communication | We sought to investigate the importance of systemic inflammation, assessed by interleukin-6 (IL-6) in comatose survivors of out-of-hospital cardiac arrest. | 26525271 |
| Inflammation, Injury wounds, Diabetes Mellitus, Non-Insulin-Dependent | Altered Intercellular Communication | Increased expression of TLR9 associated with pro-inflammatory S100A8 and IL-8 in diabetic wounds could lead to unresolved inflammation in type 2 diabetes mellitus (T2DM) cases with impaired wound healing. | 26525587 |
| Inflammation, Ulcer | Altered Intercellular Communication | Immune dys-regulation is the hallmark of T2DM that could contribute to prolonged inflammation causing transformation of wounds into non-healing chronic ulcers. | 26525587 |
| Inflammation | Altered Intercellular Communication | We hypothesized that pro-inflammatory S100A8 and IL-8 proteins could cause persistent inflammation in chronic wounds like diabetic foot ulcer (DFU) and may contribute to impaired wound healing in T2DM patients. | 26525587 |
| ARCN1 gene, Bacterial Infections, Airway structure | Altered Intercellular Communication | Smoking-induced COPD is characterized by chronic airway inflammation, which becomes enhanced by bacterial infections resulting in accelerated disease progression called exacerbation. | 26526351 |
| Inflammation, Progranulins, Subarachnoid Hemorrhage | Altered Intercellular Communication | Decreased progranulin levels in patients and rats with subarachnoid hemorrhage: a potential role in inhibiting inflammation by suppressing neutrophil recruitment. | 26527034 |
| Progranulins, GRN wt Allele | Altered Intercellular Communication | Progranulin (PGRN) is known to be involved in various biological functions, such as anti-inflammation and tissue repair. | 26527034 |
| Inflammation, Asthma | Altered Intercellular Communication | We demonstrate that eosinophil-dominant inflammation starts in ethmoidal sinus clinicopathogenetically in CRS with asthma. | 26527517 |
| Inflammatory abnormality of the eye | Altered Intercellular Communication | Quantifying Ocular Surface Inflammation and Correlating It With Inflammatory Cell Infiltration In Vivo: A Novel Method. | 26529042 |
| Inflammation, Malignant Neoplasms | Altered Intercellular Communication | C-reactive protein (CRP), an acute phase protein synthesized primarily in the liver, is a marker for inflammation and for the progression of many cancers. | 26529498 |
| Hemangioma, Cavernous | Altered Intercellular Communication | [Granulomatous inflammation in the bed of resected cerebral cavernoma in a child, caused by a hemostatic agent]. | 26529626 |
| Granuloma, Hemangioma, Cavernous, Inflammation | Altered Intercellular Communication | The study presents a clinical observation of foreign body granuloma, which is rare productive inflammation, developed on treatment with a hemostatic material upon removal of cerebral cavernoma. | 26529626 |
| Inflammation, Granuloma | Altered Intercellular Communication | Inflammation was accompanied by the formation of foreign body granulomas, and, in some areas, had immune nature with signs of focal destructive vasculitis, delayed maturation of the granulation tissue, and disturbance of the current organization and encapsulation processes. | 26529626 |
| Granulomatous inflammation, Neoplasms | Altered Intercellular Communication | It is worth noting that granulomatous inflammation around a hemostatic material in the brain has no specific features during introscopy and mimics an abscess or tumor recurrence. | 26529626 |
| Granulomatous inflammation | Altered Intercellular Communication | To prevent granulomatous inflammation, removal of a hemostatic material, if possible, from the surgical field is recommended when reliable hemostasis is achieved. | 26529626 |
| Inflammation, Muscle of pelvic diaphragm, Bacterial Infections, Brain Damage, Chronic | Altered Intercellular Communication | Pelvic floor muscle abnormalities, altered neuroendocrine pathways, chemically induced inflammation, bacterial infection, autoimmune processes, dysfunctional voiding as well intraprostatic ductal reflux mechanisms have all been identified in men with chronic pelvic pain syndrome. | 26529825 |
| Trachoma | Altered Intercellular Communication | The overall prevalence of active trachoma among children aged 1-9 years were 23.1 % (Trachomatous inflammation-Follicular, in 22.5 % (95 % CI: 22.3-22.69 %); Trachomatous inflammation-Intense, in 0.6 % (95 % CI: 0.4-0.79 %). | 26530131 |
| Inflammation, Rheumatoid Arthritis | Altered Intercellular Communication | Signs of immune activation and local inflammation are present in the bronchial tissue of patients with untreated early rheumatoid arthritis. | 26530319 |
| Primary malignant neoplasm | Altered Intercellular Communication | The Glasgow Prognostic Score (GPS), calculated from the serum levels of CRP and albumin, is well known to be a valuable inflammation-based prognostic system for several types of cancer. | 26530445 |
| Colorectal Carcinoma | Altered Intercellular Communication | CAR is as useful for predicting the postoperative survival of patients with CRC as previously reported inflammation-based prognostic systems, such as GPS and NLR. | 26530445 |
| Hereditary Autoinflammatory Diseases, Inflammation, NLRP3 gene | Altered Intercellular Communication | Muckle-Wells-syndrome (MWS) is an autoinflammatory disease characterized by systemic and organ-specific inflammation due to excessive interleukin (IL)-1 release. | 26531310 |
| Inflammation, Sensorineural Hearing Loss (disorder) | Altered Intercellular Communication | Inner ear inflammation results in irreversible sensorineural hearing loss, if untreated. | 26531310 |
| Inflammation, NLRP3 gene | Altered Intercellular Communication | Early inner ear inflammation in MWS primarily affects the high frequencies, beyond the range of standard otologic assessment tools. | 26531310 |
| Intraocular inflammation, Hemorrhagic | Altered Intercellular Communication | Examination disclosed intraocular inflammation, along with plain white peripheral non-exudative lesions with sparse haemorrhaging. | 26531739 |
| Inflammation, Atherosclerosis, Cardiovascular Diseases, Endothelial dysfunction, Ischemic stroke | Altered Intercellular Communication | Chronic inflammation that triggers endothelial dysfunction and atherosclerosis may promote the evolution of cardiovascular diseases, including acute ischemic stroke (AIS). | 26534741 |
| Inflammation, Cerebrovascular accident | Altered Intercellular Communication | We hypothesized that air pollution, an inflammation progenitor, can be associated with stroke incidence in young patients in whom the usual risk factors for stroke are less prevalent. | 26534971 |
| Inflammation | Altered Intercellular Communication | The inflammation results from the phagocytosis of monosodium urate crystals (MSU) and the release of inflammatory cytokines within the joint. | 26535601 |
| Inflammation | Altered Intercellular Communication | A biopsy identified chronic inflammation of the mucosa and tissue. | 26535832 |
| Inflammatory Bowel Diseases, Gastrointestinal inflammation | Altered Intercellular Communication | Fecal calprotectin is a reliable noninvasive marker for intestinal inflammation usable for monitoring patients with inflammatory bowel disease. | 26535869 |
| Inflammatory Bowel Diseases, Inflammation | Altered Intercellular Communication | The CalproSmart test performed by patients with inflammatory bowel disease for fast assessment of gut inflammation seems a reliable alternative to ELISA and presents a new way of monitoring patients by eHealth. | 26535869 |
| Inflammation, Ulcerative Colitis, Crohn Disease | Altered Intercellular Communication | CCL20 and CCR6 mRNA abundances were increased during active inflammation (CCL20 5.4-fold in ulcerative colitis and 4.2-fold in Crohn's disease; CCR6 1.8 and 2.0, respectively). | 26536229 |
| Inflammation | Altered Intercellular Communication | CCL20 and CCR6 mRNA positive immune cells in lamina propria were more numerous, and CCL20 immunoreactivity increased massively in the epithelial cells during active inflammation for both diseases. | 26536229 |
| Inflammation, Ulcerative Colitis, Crohn Disease | Altered Intercellular Communication | The CCL20-CCR6 axis is involved during active inflammation in both ulcerative colitis and Crohn's disease. | 26536229 |
| Inflammation, Rupture, Periodontal Diseases, Dental Plaque, Periodontal Ligament | Altered Intercellular Communication | Periodontal disease has been associated with cardio- and cerebrovascular events, and inflammation in the periodontium is suggested to increase the systemic inflammatory level of the host, which may in turn influence plaque composition and rupture. | 26536303 |
| Inflammatory abnormality of the eye | Altered Intercellular Communication | Visual acuity and ocular inflammation scores before and 6 months after surgery were compared. | 26536452 |
| Inflammation, Uveitis | Altered Intercellular Communication | In granulomatous uveitis, the mean inflammation scores decreased significantly both in the anterior segment and in the posterior segment. | 26536452 |
| Inflammation, Uveitis | Altered Intercellular Communication | In nongranulomatous uveitis, the mean inflammation score in the posterior segment decreased significantly, although it did not change in the anterior segment. | 26536452 |
| ARCN1 gene, Communicable Diseases, Tooth Loss, Inflammation | Altered Intercellular Communication | An increased understanding of causal mechanisms linking cigarette smoking, oral health, and COPD, particularly the role of tooth loss, infection, and subsequent inflammation, is essential to reduce the burden of COPD. | 26537367 |
| Inflammation, Hemorrhage, Trauma, Nervous System, Seizures, Cessation of life | Altered Intercellular Communication | The iCKO mice developed severe seizures accompanied by neuronal injury, multiple brain petechial hemorrhages, and central nervous system inflammation, and all had postictal death. | 26538583 |
| Seizures, Inflammation, physiopathological, Brain hemorrhage | Altered Intercellular Communication | The results suggest that BBB dysfunction secondary to defective b-catenin transcription activity is a key pathogenic factor in hemorrhagic stroke, seizure activity, and central nervous system inflammation. | 26538583 |
| Inflammation, Fibrosis Assessment, Hepatitis, Liver Dysfunction | Altered Intercellular Communication | For any degree of fibrosis, >= moderate inflammation on histology or HCV hepatitis accompanying with abnormal liver function, we treated with pegylated interferon and ribavirin. | 26539000 |
| Mediastinitis | Altered Intercellular Communication | Esophageal reconstruction was performed after controlling the mediastinal inflammation. | 26539019 |
| Aneurysm | Altered Intercellular Communication | Activation of Endocannabinoid System Is Associated with Persistent Inflammation in Human Aortic Aneurysm. | 26539497 |
| Inflammation, Aortic Aneurysm | Altered Intercellular Communication | Human aortic aneurysms have been associated with inflammation and vascular remodeling. | 26539497 |
| Inflammation, Aortic Aneurysm | Altered Intercellular Communication | Since the endocannabinoid system modulates inflammation and tissue remodeling, we investigated its components in human aortic aneurysms. | 26539497 |
| Inflammation, Aortic Aneurysm | Altered Intercellular Communication | Our data provides evidence for endocannabinoid system activation in human aortic aneurysms, associated with persistent low-level inflammation and vascular remodeling. | 26539497 |
| Inflammation | Altered Intercellular Communication | Hepcidin and neutrophil-gelatinase associated lipocalin (NGAL) are induced by inflammation and these proteins may take role in ESA resistance. | 26539647 |
| Inflammation, Respiratory Distress Syndrome, Newborn | Altered Intercellular Communication | Interleukin-17A Is Associated With Alveolar Inflammation and Poor Outcomes in Acute Respiratory Distress Syndrome. | 26540401 |
| Inflammation, Lung Injury | Altered Intercellular Communication | Interleukin-17A is a proinflammatory cytokine known to play a role in host defense and pathologic inflammation in murine models of lung injury. | 26540401 |
| Inflammation, Lung Injury | Altered Intercellular Communication | The relationship between interleukin-17A and inflammation in human lung injury is unknown. | 26540401 |
| Respiratory Distress Syndrome, Adult, Inflammation, Traumatic injury | Altered Intercellular Communication | Our primary objective was to determine whether interleukin-17A levels are associated with alveolar measures of inflammation and injury in patients with acute respiratory distress syndrome. | 26540401 |
| Peripheral Vascular Diseases, Inflammation, Myocardial Ischemia, Malignant Neoplasms | Altered Intercellular Communication | Neutrophil-lymphocyte ratio (NLR) is a marker of systemic inflammation that has been shown to predict mortality in patients with malignancies, ischemic heart disease and peripheral vascular disease. | 26540580 |
| Inflammation, AATF wt Allele | Altered Intercellular Communication | These changes, which reflect the degree of immune activation and inflammation in DED, can be used for clinical practice and endpoints in clinical trials. | 26540656 |
| Degenerative polyarthritis, Inflammation, physiopathological | Altered Intercellular Communication | However, there is no scientific evidence that regular swimming reduces vascular dysfunction and inflammation and elicits similar benefits compared with land-based exercises such as cycling in terms of reducing vascular dysfunction and inflammation in patients with OA. | 26541906 |
| Common Variable Immunodeficiency | Altered Intercellular Communication | Common variable immunodeficiency (CVID) is an antibody deficiency treated with immunoglobulin; however, patients can have noninfectious inflammatory conditions that lead to heightened morbidity and mortality. | 26542033 |
| Inflammation, Fibrosis Assessment, Neuronal loss in central nervous system | Altered Intercellular Communication | Pathology specimens were graded on degree of neuronal loss, inflammation, fibrosis, and muscle changes. | 26542087 |
| Inflammation, Fibrosis Assessment, Muscular Atrophy | Altered Intercellular Communication | On histopathology, complete ganglion cell loss occurred in 74% of specimens, inflammation in 17%, fibrosis in 11%, and muscle atrophy in 2%. | 26542087 |
| Achalasia, Inflammation, Pyloric Stenosis, Neuronal loss in central nervous system | Altered Intercellular Communication | The spectrum of histopathologic findings - from complete neuronal loss to lymphocytic inflammation to apparently normal histopathology - emphasizes that 'achalasia' represents a pathogenically heterogeneous patient group with the commonality being EGJ outflow obstruction. | 26542087 |
| Chronic disease | Altered Intercellular Communication | Increased oxidative stress (OS) has been implicated in a variety of chronic diseases, inflammatory conditions, aging, and even following intense physical exercise. | 26542596 |
| Inflammation, Thrombophilia | Altered Intercellular Communication | Correlation of Inflammation and Lipoprotein (a) with Hypercoagulability in Hemodialysis Patients. | 26543308 |
| Inflammation, ciliary vesicle | Altered Intercellular Communication | Classical CV disease risk factors were recorded and systemic inflammation was determined by the measurement of C-reactive protein (CRP) and erythrocyte sedimentation rate (ESR). | 26543327 |
| Inflammation, Necrosis | Altered Intercellular Communication | Pathological assessment of necrosis, inflammation and proliferation index was also performed. | 26544728 |
| Inflammation, Mesothelioma, Necrosis | Altered Intercellular Communication | Sarcomatoid/biphasic and epithelioid mesotheliomas showed different MDM2 and HIF1alpha expression levels and were characterized by different levels of necrosis, proliferation and inflammation. | 26544728 |
| Inflammation, Colorectal Carcinoma | Altered Intercellular Communication | The neutrophil-to-lymphocyte ratio (NLR) is considered an indicator of systemic inflammation and may predict prognosis in colorectal cancer. | 26544755 |
| Inflammation, Spinal Cord Injuries | Altered Intercellular Communication | Targeting inflammation to influence mood following spinal cord injury: a randomized clinical trial. | 26545369 |
| Inflammation, Depression, CTCAE | Altered Intercellular Communication | Due to the limited sample size, results should be interpreted with caution; however, they are worthy of further examination due to the potential impact of inflammation on depression. | 26545369 |
| Weight Gain | Altered Intercellular Communication | the hormonal decline that is characteristic of the menopause, in conjunction with the associated weight gain, is considered a determinant factor of cardiovascular risk. | 26545524 |
| Esophageal and Gastric Varices, Duodenal inflammation | Altered Intercellular Communication | Esophageal, gastric, and duodenal inflammation were detected in 21%, 74%, and 37% of patients, respectively. | 26545803 |
| Inflammation | Altered Intercellular Communication | Interleukin (IL)-17 has been shown to play an important role in tissue inflammation and in the pathogenesis of immune-related liver damage. | 26546176 |
| Inflammation, Heart failure | Altered Intercellular Communication | Patients with heart failure (HF) have evidence of chronic systemic inflammation. | 26546248 |
| Inflammation, hafnium, Impaired exercise tolerance | Altered Intercellular Communication | Whether inflammation contributes to the exercise intolerance in patients with HF is, however, not well established. | 26546248 |
| Inflammation, Myocardial Ischemia | Altered Intercellular Communication | In conclusion, the intensity of systemic inflammation, measured as CRP plasma levels, is associated with cardiopulmonary exercise performance, in patients with ischemic heart disease and chronic systolic HF. | 26546248 |
| Communicable Diseases, Chronic pulmonary aspergillosis, Inflammation | Altered Intercellular Communication | Response to vaccination has not been studied in chronic lung conditions characterised by ongoing infection or inflammation like chronic pulmonary aspergillosis (CPA). | 26546263 |
| Small cell carcinoma of lung, Inflammation, Sarcopenia | Altered Intercellular Communication | Sarcopenia and inflammation are independent predictors of survival in male patients newly diagnosed with small cell lung cancer. | 26546456 |
| Inflammation, Sarcopenia | Altered Intercellular Communication | Sarcopenia is suggested to be associated with cancer-related inflammation. | 26546456 |
| HD Term Type, Hypokinesia | Altered Intercellular Communication | These results identify impairment of cortico-striatal synaptic transmission and dopamine release as a potential basis of hypokinesia in HD. | 26546830 |
| Nasopharyngitis, Diarrhea, Folliculitis | Altered Intercellular Communication | The most common AE in the brodalumab groups were nasopharyngitis (12.4% vs. 7.9% for placebo), diarrhea (5.3% vs. 0%), upper respiratory tract inflammation (3.5% vs. 0%), and folliculitis (3.5% vs. 0%). | 26547109 |
| Inflammation, Malignant Neoplasms | Altered Intercellular Communication | Chronic inflammation increases the risk of development of human malignancies. | 26547585 |
| Inflammation, Diabetes Mellitus | Altered Intercellular Communication | GlycA is a recently developed glycoprotein biomarker of systemic inflammation that may be predictive of incident type 2 diabetes mellitus (T2DM). | 26549655 |
| Inflammation, Infectious Lung Disorder, Pulmonary Valve Insufficiency, Cystic Fibrosis | Altered Intercellular Communication | After repeated cycles of lung infection and inflammation, patients with cystic fibrosis (CF) evolve to respiratory insufficiency. | 26551917 |
| Inflammation, Aortitis, Granuloma | Altered Intercellular Communication | The final diagnosis of tuberculous aortitis was made on the basis of macroscopic appearance of inflammation and microscopic confirmation of caseating granuloma. | 26553119 |
| Inflammation, Asthma | Altered Intercellular Communication | The ADAM family is involved in some pathologic processes, such as inflammation and asthma. | 26553447 |
| Degenerative polyarthritis, Pain Distress Question | Altered Intercellular Communication | Association of Joint Inflammation With Pain Sensitization in Knee Osteoarthritis: The Multicenter Osteoarthritis Study. | 26554395 |
| Degenerative polyarthritis, Inflammation, Bone Marrow, Synovitis | Altered Intercellular Communication | We examined whether inflammation, assessed as synovitis and effusion on magnetic resonance imaging (MRI), or mechanical load, assessed as bone marrow lesions (BMLs), was associated with sensitization in knee OA. | 26554395 |
| Inflammation, Pain Distress Question, Synovitis, Degenerative polyarthritis, effusion | Altered Intercellular Communication | Inflammation, as evidenced by synovitis or effusion, is associated with pain sensitization in knee OA. | 26554395 |
| Degenerative polyarthritis, Inflammation, Pain Distress Question | Altered Intercellular Communication | Early targeting of inflammation is a reasonable strategy to test for prevention of sensitization and through this, reduction of pain severity, in knee OA. | 26554395 |
| Hepatic inflammation, Hepatitis B, Chronic | Altered Intercellular Communication | The macrophage activation marker CD163 is associated with IL28B genotype and hepatic inflammation in chronic hepatitis C virus infected patients. | 26554542 |
| Communicable Diseases, Fibrosis Assessment, Inflammation | Altered Intercellular Communication | Recent data highlighted the association of the macrophage activation marker CD163 with histological inflammation and fibrosis in chronic hepatitis C virus (HCV) infection. | 26554542 |
| Inflammation, Fibrosis Assessment | Altered Intercellular Communication | In the multivariate logistic regression analyses, sCD163 was independently associated with histologically determined inflammation (P = 0.043) but not with fibrosis (P = 0.091). | 26554542 |
| Inflammation, Clear-cell metastatic renal cell carcinoma | Altered Intercellular Communication | Interleukin-6 (IL-6) is the major cytokine that induces transcriptional acute and chronic inflammation responses, and was recently incorporated as a recurrence prognostication signature for localised clear-cell renal cell carcinoma (ccRCC). | 26554658 |
| Inflammation | Altered Intercellular Communication | As pelvic enthesitis indicates active inflammation, it may play a role in assessment of the inflammatory status. | 26554668 |
| Inflammation, Cardiovascular Diseases | Altered Intercellular Communication | Inflammation and hemostasis contribute to the etiology of cardiovascular disease. | 26554758 |
| Juvenile arthritis, Rheumatoid Arthritis, Inflammation | Altered Intercellular Communication | The purpose of this study was to investigate the presence of bacterial DNA in synovial fluid, and to compare this with clinical and immunological findings in children with JIA, adults with persistent JIA, and adults with rheumatoid arthritis, in order to detect whether bacteria contribute to inflammation in TMJ arthritis. | 26554824 |
| Inflammation | Altered Intercellular Communication | Finally, global knee inflammation (GKI) for each knee joint was calculated as the sum of cMVP mean in all segmented regions. | 26555103 |
| Inflammation, Degenerative disorder | Altered Intercellular Communication | As degenerative disease is age-related and inflammation is implicated in its pathogenesis, our findings further support this association. | 26555103 |
| Inflammation, Arthropathy | Altered Intercellular Communication | These preliminary data suggest that this approach can potentially provide a means to objectively quantify the degree of inflammation in various joint disorders, and possibly in other knee degenerative/inflammatory diseases. | 26555103 |
| Inflammation | Altered Intercellular Communication | Moreover, the possible causal relationship between calcifying vascular smooth muscle cells and inflammation was explored in vitro. | 26555788 |
| Inflammation, Calcinosis | Altered Intercellular Communication | In vitro experiments using human vascular smooth muscle cells (hVSMCs) were performed to evaluate causal relationships between calcification and inflammation. | 26555788 |
| Inflammation, Calcinosis, Failure (biologic function) | Altered Intercellular Communication | Our findings suggest that loss of calcification inhibitors and/or failure of inhibitory capacity is causative for the early precipitation of calcium, with concomitant increased inflammation followed by osteochondrogenic transdifferentiation of VSMCs. | 26555788 |
| Inflammation, De Quervain Disease | Altered Intercellular Communication | The greater the levels of ER-b expression, tissue inflammation, and angiogenesis are, the more severe de Quervain's disease is. | 26556342 |
| Malignant neoplasm of liver, Inflammation, FAM126A gene | Altered Intercellular Communication | Inflammation and diet have been suggested to be important risk factors for hepatocellular cancer (HCC). | 26556602 |
| Refractory anemias, Inflammation | Altered Intercellular Communication | The amelioration of inflammation, particularly via IL-17 antagonism, might be a new therapeutic approach for enhancing intrinsic cartilage repair mechanisms in RA patients. | 26558442 |
| Inflammation, Non-cirrhotic | Altered Intercellular Communication | Lobular inflammation was present in 63.6 % of non-cirrhotic patients. | 26558795 |
| Helicobacter pylori, Gastritis | Altered Intercellular Communication | Helicobacter pylori (H. pylori) -induced gastric inflammation impacts the functions of leptin- and ghrelin-producing cells in the gastroduodenum. | 26559190 |
| Inflammation, Primary malignant neoplasm, Blood Vessel | Altered Intercellular Communication | Cancer and its treatment may affect cognitive function through a number of direct and indirect pathways including inflammation, lipid metabolism, vascular damage, and changes in the blood-brain barrier. | 26559193 |
| Inflammation, Neoplasms | Altered Intercellular Communication | Increasing emphasis is put on the concept that inflammation is a key player in tumor progression. | 26560001 |
| Follicular conjunctivitis, Pseudolymphoma | Altered Intercellular Communication | When a chronic follicular conjunctivitis is refractory to treatment, it is essential to perform an incisional biopsy to establish the histopathological diagnosis that can range from chronic inflammation, reactive lymphoid hyperplasia to lymphoma. | 26560164 |
| Inflammation, Metabolic Syndrome X, ETV3 wt Allele | Altered Intercellular Communication | The metabolic syndrome (MetS) is associated with a chronic low-grade inflammatory state and may be affected by the ability to resolve inflammation, which is an active process that involves specialized proresolving lipid mediators (SPMs) derived from n-3 (o-3) fatty acids. | 26561623 |
| Malignant neoplasm of liver, Inflammation, Primary malignant neoplasm, Liver damage | Altered Intercellular Communication | The association of coffee intake with liver cancer risk is mediated by biomarkers of inflammation and hepatocellular injury: data from the European Prospective Investigation into Cancer and Nutrition. | 26561631 |
| Inflammation, Liver damage, FAM126A gene | Altered Intercellular Communication | These data suggest that the inverse association of coffee intake with HCC risk was partly accounted for by biomarkers of inflammation and hepatocellular injury. | 26561631 |
| Inflammation, Liver neoplasms | Altered Intercellular Communication | Exposure to fine particulate matter (PM2.5) may promote hepatic tumorgenesis through low-grade inflammation. | 26561636 |
| Malignant neoplasm of liver, Hepatitis | Altered Intercellular Communication | Long-term PM2.5 exposure increased the risk for liver cancer, and chronic inflammation of the liver may underlie the pathogenesis. | 26561636 |
| Fibrillation, Inflammation, Myopathy, Myositis | Altered Intercellular Communication | Electromyography revealed myopathy with fibrillation potentials; 78% of biopsies had active necrotizing myopathy with minimal inflammation, and 17% had inflammatory myopathy. | 26561982 |
| Intraocular inflammation, Unknown (origin) (qualifier value), Dermatitis, Atopic, Data types - Address, Congenital MeSH qualifier, Traumatic injury, Myopia | Altered Intercellular Communication | The most common aetiology for RRD was idiopathic (28.6%), followed by high myopia (24.5%), atopic dermatitis (AD) (18.4%), congenital and developmental abnormalities (16.3%), trauma (8.2%), and intraocular inflammation (4.1%). | 26563656 |
| Inflammation, Anemia | Altered Intercellular Communication | Therefore, we examined the association between frailty and a range of serum markers on inflammation, anaemia, the metabolic system, micronutrients and renal functioning. | 26563885 |
| Inflammation, Anemia | Altered Intercellular Communication | Frailty appears associated with inflammation (IL-6 and CRP), anaemia, metabolic markers (glucose, cholesterol and albumin) and renal functioning (cystatin-C and creatinine). | 26563885 |
| Inflammation, Dental Plaque | Altered Intercellular Communication | We hypothesised that patients with unstable carotid plaque have higher levels of circulating microparticles compared to patients with stable plaques, and may correlate with serum markers of plaque instability and inflammation. | 26564003 |
| Renal Insufficiency, Inflammation, Cognition Disorders, Data types - Address | Altered Intercellular Communication | J147 reduced cognitive deficits in old SAMP8 mice, while restoring multiple molecular markers associated with human AD, vascular pathology, impaired synaptic function, and inflammation to those approaching the young phenotype. | 26564964 |
| Inflammatory Bowel Diseases | Altered Intercellular Communication | Taken together, our GWAS-based analysis and in vitro and in vivo studies have demonstrated that Nur77 is an important regulator of TRAF6/TLR-IL-1R-initiated inflammatory signalling, and loss of Nur77 may contribute to the development of IBD, suggesting Nur77 as a potential target for the prevention and treatment of IBD. | 26564988 |
| Inflammation, Metabolic Syndrome X, ETV3 wt Allele | Altered Intercellular Communication | Metabolic syndrome (MetS) has been identified to be associated with a state of chronic, low-grade inflammation in adipose tissue. | 26565966 |
| Hyperglycemia, Inflammation, Diabetes Mellitus, Non-Insulin-Dependent | Altered Intercellular Communication | Type 2 diabetes and critical illness have phenotypical similarities, such as hyperglycaemia, insulin resistance and systemic inflammation. | 26567860 |
| Thrombotic Microangiopathies, Inflammation, Breast Carcinoma | Altered Intercellular Communication | The Potential Role of Inflammation Associated with Interaction between Osteopontin and CD44 in a Case of Pulmonary Tumor Thrombotic Microangiopathy Caused by Breast Cancer. | 26568002 |
| Inflammation | Altered Intercellular Communication | These findings suggest that inflammation associated with the interaction between osteopontin and CD44 may play an important role in PTTM. | 26568002 |
| Inflammation, Specimen Source Codes - Abscess | Altered Intercellular Communication | Recovery was uneventful until he experienced inflammation of the groin, and required open drainage three times for a refractory abscess in his right groin. | 26568391 |
| Inflammation | Altered Intercellular Communication | The mesh was successfully removed under general anesthesia, and the inflammation in the groin resolved. | 26568391 |
| Inflammation, Metabolic Diseases, Hyperuricemia, Gout | Altered Intercellular Communication | Gout is a common metabolic disorder characterized by hyperuricemia and chronic inflammation. | 26568484 |
| Inflammation | Altered Intercellular Communication | Inflammation, Oxidative Stress, and Antioxidants Contribute to Selected Sleep Quality and Cardiometabolic Health Relationships: A Cross-Sectional Study. | 26568665 |
| Inflammation | Altered Intercellular Communication | Our results provide initial evidence of a potential role for inflammation, oxidative stress, and antioxidants in the pathway between poor sleep quality-cardiometabolic decline. | 26568665 |
| Carcinoma of bladder | Altered Intercellular Communication | Predictive value of pretreatment inflammation-based prognostic scores (neutrophil-to-lymphocyte ratio, platelet-to-lymphocyte ratio, and lymphocyte-to-monocyte ratio) for invasive bladder carcinoma. | 26568792 |
| Inflammation | Altered Intercellular Communication | Psychological distress may contribute to chronic activation of acute-phase inflammation. | 26569541 |
| Inflammation, Colorectal Carcinoma, Ulcerative Colitis | Altered Intercellular Communication | Prolonged inflammation of colon in UC patients increases the risk of developing colorectal cancer. | 26569605 |
| Inflammation, Primary malignant neoplasm | Altered Intercellular Communication | MiRNA are reported as a connecting link between inflammation and cancer. | 26569605 |
| Airway structure, Asthma, Bronchial Hyperreactivity | Altered Intercellular Communication | The pathophysiology of asthma is multifaceted, and is characterized by restriction of airflow into and out of the lungs, airway inflammation with increased mucus production, and bronchial hyper-reactivity caused by exposure to environmental irritants and chemicals, often referred to as triggers, which in some cases are modifiable. | 26571284 |
| Hyperuricemia | Altered Intercellular Communication | Lowering Uric Acid With Allopurinol Improves Insulin Resistance and Systemic Inflammation in Asymptomatic Hyperuricemia. | 26571421 |
| Inflammation, Hyperuricemia | Altered Intercellular Communication | Allopurinol lowers uric acid and improves insulin resistance and systemic inflammation in asymptomatic hyperuricemia. | 26571421 |
| TNF protein, human, Tumor necrosis, Inflammation, Colorectal Carcinoma | Altered Intercellular Communication | Tumor necrosis factor-alpha (TNF-a) contributes in inflammation and has been implicated in the development of colorectal cancer (CRC). | 26572151 |
| Inflammation | Altered Intercellular Communication | Recent advances have highlighted the essential role of inflammation in the development of the disease. | 26572732 |
| Inflammation, Failure, Angular, Data types - Address | Altered Intercellular Communication | Multiple genes and molecular mechanisms have been implicated in AD, including ss-amyloid deposition in the brain, neurofibrillary tangle accumulation of hyper-phosphorylated Tau, synaptic failure, oxidative stress and inflammation. | 26573292 |
| Airway structure, Allergic asthma | Altered Intercellular Communication | Accordingly, knockdown of CCR2 in UCB-MSCs significantly improved their therapeutic ability to alleviate airway inflammation in an experimental allergic asthma model. | 26573462 |
| Peripheral arterial occlusive disease, Inflammation, Ulcer | Altered Intercellular Communication | For PEDIS single criteria, significantly lower overall complication rates were found for patients without signs of occlusive peripheral artery disease, an ulcer extent <0.9 cm(2), ulcer depth including erosion and inflammation of the skin and subcutaneous tissues only. | 26573860 |
| Inflammation | Altered Intercellular Communication | Inflammation and oxidative stress improved significantly in the liraglutide group compared to the placebo group. | 26573925 |
| Inflammation, Fibrosis Assessment | Altered Intercellular Communication | Fibrosis was more frequently classified as inflammation with MR-E compared with PET/MR-E [p = 0.019]. | 26574490 |
| Inflammation, Atherosclerosis | Altered Intercellular Communication | Associations Between Cardiovascular Risk Factors, Inflammation, and Progression of Carotid Atherosclerosis Among Smokers. | 26574552 |
| Inflammation | Altered Intercellular Communication | It also stimulates cell migration and structural support, provides moisture environment, decreases inflammation, and induces cell proliferation and cellular attachments. | 26574754 |
| Heredity, Inflammation, contagion | Altered Intercellular Communication | Ninety-six percent of the patients believed that there were also medical causes (such as an illness, brain insult, inflammation, heredity, contagion), and a similar proportion believed that there were also religious causes. | 26575254 |
| Inflammation, Insemination, Artificial, Homologous | Altered Intercellular Communication | By contrast, levels of circulating miR-21 showed a significant correlation with the histological grades of inflammation in AIH. | 26575387 |
| Inflammation, Diabetes Mellitus, Non-Insulin-Dependent, physiopathological, Bipolar Disorder | Altered Intercellular Communication | Elucidating the Biological Mechanisms Linking Depressive Symptoms With Type 2 Diabetes in Men: The Longitudinal Effects of Inflammation, Microvascular Dysfunction, and Testosterone. | 26575859 |
| Inflammation, Diabetes Mellitus, Non-Insulin-Dependent, physiopathological, Bipolar Disorder | Altered Intercellular Communication | This prospective cohort study sought to examine key biological measures linking depressive symptoms with Type 2 diabetes, specifically inflammation, microvascular dysfunction, and androgens. | 26575859 |
| Craniocerebral Trauma, Cognition Disorders | Altered Intercellular Communication | A single-nucleotide polymorphism in catechol-o-methyltransferase (COMT), an enzyme which degrades catecholamine neurotransmitters, may influence cognitive deficits following moderate and/or severe head trauma. | 26576546 |
| Macular Edema, Cystoid, Vitreous inflammatory cells | Altered Intercellular Communication | Best-corrected visual acuity (VA), complications, resolution of cystoid macular edema (CME), and anterior chamber and vitreous inflammation were assessed. | 26576712 |
| Vitreous inflammatory cells | Altered Intercellular Communication | There were no significant differences in baseline VA, anterior chamber and vitreous inflammation, presence of CME, and prior use of regional corticosteroid injections. | 26576712 |
| Inflammation | Altered Intercellular Communication | T cell inflammation plays pivotal roles in obesity-associated type 2 diabetes (T2DM). | 26576827 |
| Inflammation | Altered Intercellular Communication | The identification of dominant sources of T cell inflammation in humans remains a significant gap in understanding disease pathogenesis. | 26576827 |
| Inflammation | Altered Intercellular Communication | It was hypothesized that cytokine profiles from circulating T cells identify T cell subsets and T cell cytokines that define T2DM-associated inflammation. | 26576827 |
| Inflammation | Altered Intercellular Communication | Multivariate analyses indicated that B cells support Th17 inflammation in T2DM but not control samples, while monocytes supported Th17 inflammation regardless of T2DM status. | 26576827 |
| Inflammation, Hyperglycemia | Altered Intercellular Communication | Among various T cell subsets, Th17 cells are major contributors to inflammation and hyperglycemia and are uniquely supported by B cells in obesity-associated T2DM. | 26576827 |
| Mycosis Fungoides, Inflammation | Altered Intercellular Communication | Mycosis fungoides (MF) and parapsoriasis display increased inflammation, which may be associated with increased risk of arterial cardiovascular events. | 26576854 |
| Malabsorption Syndrome, physiopathological, Growth Disorders | Altered Intercellular Communication | Environmental enteric dysfunction (EED), a pervasive chronic subclinical inflammatory condition among children that develops when complementary foods are introduced, places them at high risk of stunting, malabsorption, and poor oral vaccine efficacy. | 26578308 |
| Granulomatosis, Scleritis, Sudden Visual Loss, Orbital Pseudotumor, Vasculitis, Systemic Vasculitis | Altered Intercellular Communication | A 24-year-old woman with a clinical history of granulomatosis with polyangiitis who presented with acute vision loss was found to have frosted branch angiitis with concurrent posterior scleritis and orbital inflammation. | 26579594 |
| MTA2 gene, Inflammation, Chronic pelvic pain of female, Pelvic Inflammatory Disease | Altered Intercellular Communication | Pelvic inflammatory disease (PID) has been investigated in Western countries and identified to be associated with chronic pelvic pain and inflammation. | 26579800 |
| Inflammation, Pelvic Pain | Altered Intercellular Communication | Chronic pelvic pain is a main symptom of BPS/IC, and chronic inflammation is a major etiology of BPS/IC. | 26579800 |
| Inflammation | Altered Intercellular Communication | KLIP should not be considered a variant of classical KFD, but rather as an elementary pattern of cutaneous inflammation, that might be the expression of the same cytotoxic process within skin infiltrates as that involved in KFD. | 26579818 |
| Critical Illness | Altered Intercellular Communication | In critically ill mechanically ventilated patients, in whom microbial colonization of the upper airways is constant, collection of aEBC could considerably add to the ability of monitoring alveolar inflammation. | 26581173 |
| Inflammation, Fibrosis Assessment, Leucocytic infiltrate | Altered Intercellular Communication | In sub-acute phase, 18F-fluorodeoxyglucose positron emission tomography showed no evidence of inflammation, and repeat EMB showed a significant decrease in the inflammatory infiltration and fibrosis, including absence of giant cells. | 26581394 |
| Chagas Disease, Myocarditis | Altered Intercellular Communication | On pathology Chagas' heart disease is characterized by chronic myocardial inflammation and extensive myocardial fibrosis. | 26581396 |
| Colorectal Carcinoma | Altered Intercellular Communication | A typical inflammation-related CRC mouse model was generated using azoxymethane-dextran sodium sulfate (AOM-DSS), and TIFs were collected from these mice in four stages during CRC development. | 26581642 |
| Inflammation, Primary malignant neoplasm, Cardiovascular Diseases, Depression, CTCAE, Asthma | Altered Intercellular Communication | Stress is strongly associated with several mental and physical health problems that involve inflammation, including asthma, cardiovascular disease, certain types of cancer, and depression. | 26581830 |
| Inflammation, SDSL gene | Altered Intercellular Communication | It is believed that aberrant angiogenesis and intracapsular inflammation contribute to the development of CSDH. | 26581842 |
| Chronic lymphocytic inflammation, Pontine structure, Hepatitis B, Clippers | Altered Intercellular Communication | Chronic hepatitis B infection presenting with chronic lymphocytic inflammation with pontine perivascular enhancement responsive to steroids (CLIPPERS): a case report. | 26582039 |
| Brain Stem, Diplopia, Pontine structure, Dysarthria, CTCAE, Facial paralysis, Chronic lymphocytic inflammation, Cerebellar Ataxia | Altered Intercellular Communication | Chronic lymphocytic inflammation with pontine perivascular enhancement responsive to steroids is a brainstem disorder characterized by perivascular pathologic reaction with lymphocyte infiltration and leading to diplopia, facial palsy, dysarthria, and gait ataxia. | 26582039 |
| Chronic lymphocytic inflammation, Pontine structure, Hepatitis B, Chronic | Altered Intercellular Communication | Patients with chronic hepatitis B infection may develop the syndrome of chronic lymphocytic inflammation with pontine perivascular enhancement responsive to steroids. | 26582039 |
| Chronic lymphocytic inflammation, Pontine structure, Hepatitis B | Altered Intercellular Communication | Chronic lymphocytic inflammation with pontine perivascular enhancement responsive to steroids was diagnosed, with increased hepatitis B viral load at the same time. | 26582039 |
| Chronic lymphocytic inflammation, Pontine structure, Hepatitis B | Altered Intercellular Communication | Hepatitis B virus infection may induce central nervous system autoimmune reactions, including chronic lymphocytic inflammation with pontine perivascular enhancement responsive to steroids. | 26582039 |
| Inflammation, Adenocarcinoma of lung (disorder) | Altered Intercellular Communication | Thus, we aimed to analyze whether chronic inflammation or immunosuppression predominates at the systemic level in lung adenocarcinoma patients, and several cytokines and Th17 and Treg cells were studied. | 26582240 |
| Inflammation | Altered Intercellular Communication | Conclusions The magnitude of acute exercise-induced inflammation following upper-body resistance exercise in women with BCRL does not vary between resistance exercise loads. | 26582633 |
| Tegumentary leishmaniasis susceptibility | Altered Intercellular Communication | Unfettered inflammation is thought to play critical role in the development of different clinical forms of tegumentary leishmaniasis. | 26582954 |
| Inflammation, Autoimmune Diseases, Fibrosis Assessment, Sample Size Calculation, Microcirculatory Bed | Altered Intercellular Communication | Systemic sclerosis (SSc) is a chronic autoimmune disease characterized by microvascular damage, inflammation, and fibrosis. | 26584613 |
| Inflammation | Altered Intercellular Communication | It has become increasingly evident that platelets, beyond regulating hemostasis, are important in inflammation and innate immunity. | 26584613 |
| Inflammation, neuron death | Altered Intercellular Communication | SOD1(G93A) mice treated with ASC-CM for 7 days showed reduced levels of phosphorylated p38 (pp38) in the spinal cord, a mitogen-activated protein kinase that is involved in both inflammation and neuronal death. | 26586020 |
| Inflammation, Cerebrovascular accident | Altered Intercellular Communication | Relationship between Inflammation and Aspirin and Clopidogrel Antiplatelet Responses in Acute Ischemic Stroke. | 26586373 |
| Inflammation, Pleuropneumonia | Altered Intercellular Communication | A CT angiography scan of the chest and abdomen showed intralumen emboli in medial lobe segmen of right pulmonary artery, right pleuropneumonia with segmental lession in segmen 10 right lobe and inflammation process along right lateral wall of the abdomen. | 26586389 |
| Inflammation, MDFIC gene | Altered Intercellular Communication | Substantial lymphoplasmacytic inflammation (>=200 cells/mm2) was observed in 93% of HIC specimens, whereas only 8% of NHIC specimens were inflamed. | 26587589 |
| Neurodegenerative Disorders, "Alzheimers Disease", Data types - Address | Altered Intercellular Communication | The critical role of neuro-inflammation and oxidative stress in the pathogenesis of neurodegenerative diseases such as Alzheimer's disease (AD) has become evident. | 26587902 |
| Inflammation, Hemorrhage, Edema, Dermatitis, Hypergranulosis, Solar elastosis | Altered Intercellular Communication | Major differences between LK and LE, respectively, included perivascular inflammation (11%, 90%), high Civatte bodies (44%, 7%), solar elastosis (84%, 33%), a predominate pattern of cell-poor vacuolar interface dermatitis (7%, 73%), compact follicular plugging (11%, 50%), hemorrhage (22%, 70%), mucin (0%, 77%), hypergranulosis (44%, 17%), and edema (7%, 60%). | 26588332 |
| Inflammation, Hemorrhage, Edema | Altered Intercellular Communication | Perivascular inflammation, cell-poor vacuolar interface, compact follicular plugging, mucin, hemorrhage, and edema favored LE. | 26588332 |
| Inflammation, Ulcerative Colitis | Altered Intercellular Communication | In patients with UC with endoscopic evidence of inflammation, more (86.9 %) had FC > 200 mcg/g (cut-off for disease activity in our laboratory) than had ESR >20 mm in the first hour (60.6 %) or positive CRP (65.6 %) (< 0.01); FC levels increased with increasing endoscopic Mayo score (p = 0.001) and Truelove-Witt's clinical severity score (p = 0.006), but did not correlate with disease extent (p = 0.7). | 26589229 |
| Inflammation, Ulcerative Colitis | Altered Intercellular Communication | In patients with UC with inflammation, FC > 200 mcg/g is more often positive than raised ESR or CRP; it also correlates with clinical and endoscopic activity but not with disease extent. | 26589229 |
| Pulmonary arterial hypertension, Inflammation, Polycyclic Hydrocarbons, Aromatic | Altered Intercellular Communication | A proliferative endothelial cell phenotype, inflammation, and pulmonary vascular remodeling are prominent features of pulmonary arterial hypertension (PAH). | 26589479 |
| Inflammation, Reperfusion Injury | Altered Intercellular Communication | [Effect of Shenxiong injection on inflammation injury of ischemia-reperfusion injury rats]. | 26591534 |
| Inflammation | Altered Intercellular Communication | Moreover, CRP, Complement-3 (C3), C4 IL-4, IL-5, IL-1b and IL-17A levels of serum were investigated as an apoptotic marker and a negative marker for inflammation. | 26592187 |
| Inflammation, Allergic | Altered Intercellular Communication | In contrast to STAT3-HIES, DOCK8-HIES patients showed more severe inflammation with regard to allergic manifestations, elevated activation markers (HLA-DR, CD69, CD86, and CD154), and significantly increased inflammatory cytokines (IL1-beta, IL4, IL6, and IFN-gamma). | 26592211 |
| Inflammation, Primary malignant neoplasm, Pathology, Benign prostatic hypertrophy, Acute retention of urine, Structure of posterior cerebral artery | Altered Intercellular Communication | To explore the spectrum of pathologies diagnosed in prostatic biopsies of Saudi men, and test whether the frequency of diagnosing the malignant fraction has been changed over the last 15 years, and assess the association between chronic inflammation (CI) with both benign prostatic hyperplasia (BPH) and cancer (PCa), and investigate the histological findings of cases presented with acute urinary retention (AUR) clinically. | 26593165 |
| Inflammation, Structure of posterior cerebral artery | Altered Intercellular Communication | Chronic inflammation is more related to BPH than to PCa. | 26593165 |
| Inflammation, Hypoxia | Altered Intercellular Communication | Adipose tissue hypoxia appears to play a role in promoting chronic inflammation and the development of obesity-related cardiovascular and metabolic diseases, yet the underlying mechanisms are not well understood. | 26593323 |
| Inflammation | Altered Intercellular Communication | Sirtuins are a class of proteins with important physiologic roles in metabolism and inflammation. | 26595549 |
| pathologic fistula, Complication, Inflammatory disease of mucous membrane, Ulcer | Altered Intercellular Communication | Denovo CD was diagnosed when mucosal inflammation (5 or more ulcers) involved the small bowel mucosa proximal to the ileal pouch any time after surgery and/or when a pouch fistula or other perianal complication developed more than 3 months after ileostomy closure. | 26595552 |
| Inflammation, Diarrhea | Altered Intercellular Communication | Patients who developed denovo CD had an increased incidence of nonbloody diarrhea (n = 12; 29%) compared with patients who had no evidence of pouch inflammation (n = 25; 16%) (P = 0.03). | 26595552 |
| Inflammation, Weight decreased | Altered Intercellular Communication | In contrast, the incidence of weight loss was not significantly increased in patients with denovo CD (n = 7; 17%) compared with patients who never had pouch inflammation (n = 16; 10%) (P = 0.12). | 26595552 |
| Inflammation, Atherosclerosis | Altered Intercellular Communication | Lower heart rate variability (HRV) is associated with the inflammation that is linked with the progression of atherosclerosis. | 26595902 |
| Inflammation, Abnormal sudomotor regulation | Altered Intercellular Communication | Lowered HRV, primarily due to parasympathetic dysfunction, was associated with elevated inflammation, independent of weight, insulin sensitivity, and other related factors. | 26595902 |
| Inflammation, Pancreatitis, Pancreatic carcinoma | Altered Intercellular Communication | Diffusion-weighted MR imaging of pancreatic cancer and inflammation: Prognostic significance of pancreatic inflammation in pancreatic cancer patients. | 26596539 |
| Poi serotype, Postoperative ileus, Inflammation | Altered Intercellular Communication | Postoperative ileus (POI) is a frequent complication after abdominal surgery, resulting from an inflammation of the muscularis externa (ME). | 26596561 |
| Autoimmune Diseases, Inflammation | Altered Intercellular Communication | These findings indicate that pathogenic memory T cell responses are controlled by both CD28 and CTLA-4/PD-L1 cosignals in vivo and that selectively targeting CD28 would help to promote remission of autoimmune diseases and control chronic inflammation. | 26597009 |
| Inflammation, Pancreatitis, Pancreatic carcinoma | Altered Intercellular Communication | Subclinical Inflammation and Endothelial Dysfunction in Patients with Chronic Pancreatitis and Newly Diagnosed Pancreatic Cancer. | 26597191 |
| Inflammation, Adenocarcinoma of pancreas, Endothelial dysfunction | Altered Intercellular Communication | We studied endothelial dysfunction and subclinical inflammation in patients with newly diagnosed pancreatic adenocarcinoma and CP. | 26597191 |
| Inflammation, Diverticulum | Altered Intercellular Communication | Two observers analyzed MR images for the presence, location, number, and size of diverticula, wall thickness, and mural and extramural patterns of inflammation. | 26597545 |
| Diverticulitis | Altered Intercellular Communication | Diverticulitis occurred in 3/7 patients (43 %) showing asymmetric bowel wall thickening and focal mesenteric inflammation. | 26597545 |
| Inflammation, Multiple diverticula | Altered Intercellular Communication | Asymmetric, focal mesenteric and mural inflammation and presence of multiple diverticula are keys to diagnosis. | 26597545 |
| Bowel diverticulosis, Diverticulitis, Diverticulum, Diverticulitis of small intestine | Altered Intercellular Communication | * Small bowel diverticulosis and diverticulitis is rare and often missed in imaging * Acquired small bowel diverticula are variable in size and number * Small bowel diverticulitis demonstrates characteristic features on MR enterography/enteroclysis * A focal or segmental asymmetric small bowel inflammation should prompt the search for diverticula. | 26597545 |
| Inflammation | Altered Intercellular Communication | Importantly, we found that the skewing of circulating Tfh toward the Th1/Th17-like cells was directly correlated with B cell inflammation and low density lipoprotein level in CAD patients. | 26597829 |
| Inflammation | Altered Intercellular Communication | Together, our data demonstrated a skewing of blood Tfh composition in CAD patients, which resulted in significant changes in B cell inflammation. | 26597829 |
| Inflammation, Uveitis | Altered Intercellular Communication | All patients underwent slit lamp examination by a uveitis specialist, and the degree of scleral inflammation was recorded. | 26597942 |
| Inflammation, Secondary malignant neoplasm of liver, Primary malignant neoplasm | Altered Intercellular Communication | A positive association between hepatic metastasis (P = 0.004), primary lung cancer (P = 0.021), PC only (P < 0.001), lower Karnofsky Performance Status (P < 0.001), and higher systemic inflammation (mGPS 1/2) was found. | 26598040 |
| Minimal Disseminated Disease, Inflammation | Altered Intercellular Communication | These data demonstrate that the AA/EPA+DHA ratio moderates the effect of poor sleep on risk for developing IFN-MDD and may have broader implications for predicting and preventing MDD associated with inflammation. | 26598106 |
| Arthralgia, Rheumatoid Arthritis, Functional Disability | Altered Intercellular Communication | Rheumatoid arthritis is a chronic inflammatory condition characterized by joint pain, stiffness, and functional disability. | 26598284 |
| Inflammation, Autoinflammatory disorder | Altered Intercellular Communication | Taken together, our data envision a novel role for adaptive immunity in the pathogenesis of TNFR-associated periodic syndrome involving both CD4(+) conventional T cells and Tregs, suggesting a novel mechanism of inflammation in the context of autoinflammatory disorders. | 26598380 |
| Inflammation, Non-alcoholic Fatty Liver Disease, Metabolic Syndrome X | Altered Intercellular Communication | In addition, the incidence of metabolic syndrome and non-alcoholic fatty liver disease (NAFLD) is closely linked with the increase in inflammation and the disorders of lipid metabolism. | 26598837 |
| Inflammation, Phylum Nematoda | Altered Intercellular Communication | Nematode carcasses may remain preserved in the human eye for extended periods without ongoing inflammation. | 26599254 |
| Acute Kidney Injury, CTCAE, Inflammation, Cardiac dysfunction, Sepsis | Altered Intercellular Communication | TLR2, associated with deleterious systemic inflammation, cardiac dysfunction, and acute kidney injury, acts synergistically in sepsis. | 26599367 |
| Inflammation, diabetic | Altered Intercellular Communication | Coronary inflammation and healing influence outcomes of diabetic patients treated with Percutaneous coronary revascularization (PCI). | 26599681 |
| Inflammation | Altered Intercellular Communication | Stents covered with biodegradable polymers (bp) may offer advantages over nonerodible polymer ones, because polymer reabsorption extinguish coronary inflammation and favours healing. | 26599681 |
| Airway structure, Bronchiolitis Obliterans | Altered Intercellular Communication | We found no statistically significant association with acute cellular rejection, airway inflammation, or bronchiolitis obliterans and the presence or absence of antibodies. | 26601715 |
| Acute Lung Injury, Alveolar damage | Altered Intercellular Communication | However, biopsy specimens with DSAs had a statistically significant difference vs NABs in the setting of acute lung injury, with or without diffuse alveolar damage (p = 0.0008), in the presence of capillary neutrophilic inflammation (p = 0.0014), and in samples with endotheliitis (p = 0.0155). | 26601715 |
| Acute Lung Injury, Inflammation | Altered Intercellular Communication | Capillary inflammation, acute lung injury, and endotheliitis significantly correlated with DSAs. | 26601715 |
| Inflammation | Altered Intercellular Communication | Coronary artery bypass grafting (CABG) with conventional cardiopulmonary bypass (CPB) induces systemic inflammation. | 26602006 |
| Inflammation, Ground Glass Opacity | Altered Intercellular Communication | The inflammation promptly decreased, and follow-up chest CT revealed the disappearance of the ground-glass opacities. | 26602404 |
| Inflammation, Cholecystitis | Altered Intercellular Communication | The endoscopic retrograde cholangiopancreatography findings revealed obstruction of the cystic duct and stenosis of the hilar bile duct due to inflammation of the cystic duct or inflammation of the clamping type by cholecystitis. | 26602408 |
| Inflammation, Swyer-James Syndrome, Fibrosis Assessment, Bronchiolitis Obliterans | Altered Intercellular Communication | Swyer-James syndrome is a complication of post-infectious bronchiolitis obliterans that causes inflammation and fibrosis of the bronchial walls. | 26603001 |
| Chronic granulomatous disease, Gastrointestinal inflammation | Altered Intercellular Communication | Subclinical intestinal inflammation in chronic granulomatous disease patients. | 26603166 |
| Gastrointestinal inflammation | Altered Intercellular Communication | Fecal calprotectin concentration is a marker for intestinal inflammation. | 26603166 |
| Chronic granulomatous disease, Gastrointestinal inflammation | Altered Intercellular Communication | We sought to determine whether subclinical intestinal inflammation occurs in asymptomatic chronic granulomatous disease patients. | 26603166 |
| Retinal Detachment, Inflammation, Macular Edema, Cystoid, Eye Hemorrhage | Altered Intercellular Communication | Postoperative complications included elevated intraocular pressure (13.8%), optic capture (12.3%), persistent anterior chamber inflammation (6.2%), IOL tilt (4.6%), cystoid macular edema (3.1%), recurrent ocular hemorrhage (3.1%), and retinal detachment (1.5%). | 26603392 |
| Inflammation, Impaired cognition | Altered Intercellular Communication | Despite significantly increased inflammation observed in the older group, none of the inflammatory markers were associated with neurocognitive impairment among older HIV+ individuals (p > 0.05). | 26603568 |
| Inflammation, Asthma, Atherosclerosis | Altered Intercellular Communication | ORMDL sphingolipid biosynthesis regulator 3 (ORMDL3) is a universally confirmed susceptibility gene for asthma and has recently emerged as a crucial modulator in lipid metabolism, inflammation and endoplasmic reticulum (ER) stress-the mechanisms also closely involved in atherosclerosis (AS). | 26603569 |
| Inflammation, Colitis | Altered Intercellular Communication | IL-9 antibody injection suppresses the inflammation in colitis mice. | 26603936 |
| Inflammation, Ulcerative Colitis | Altered Intercellular Communication | Diverse T help (Th) cells play a crucial role in the processing and maintaining of chronic inflammation as seen in ulcerative colitis (UC). | 26603936 |
| Inflammation, Colitis | Altered Intercellular Communication | Anti-IL-9 antibody injection for 2 weeks reduced the severity of inflammation in DSS induced colitis mice. | 26603936 |
| Colorectal Carcinoma | Altered Intercellular Communication | Comparison of selected inflammation-based prognostic markers in relapsed or refractory metastatic colorectal cancer patients. | 26604648 |
| Colorectal Carcinoma | Altered Intercellular Communication | To investigate the impact of systemic inflammation-based prognostic markers on overall survival in relapsed/refractory metastatic colorectal cancer (mCRC) patients. | 26604648 |
| Inflammation, Dryness (characteristic) | Altered Intercellular Communication | The occurrence of repetitive dry eye is accompanied by inflammation. | 26604661 |
| Inflammation | Altered Intercellular Communication | Erdosteine reduces inflammation and time to first exacerbation postdischarge in hospitalized patients with AECOPD. | 26604731 |
| Airway structure | Altered Intercellular Communication | ER significantly reduced airway inflammation, improved the symptoms of AECOPD, and prolonged time to first exacerbation. | 26604731 |
| ARCN1 gene, Inflammation | Altered Intercellular Communication | Chronic low-grade systemic inflammation and oxidative stress play a significant role in CAD and COPD. | 26605517 |
| Inflammation, hepcidin | Altered Intercellular Communication | In our observation, IV iron infusion does not induce more nontransferrin bound iron, lipid, or protein oxidation in patients compared with volunteers, despite higher inflammation, oxidative stress, and hepcidin levels and lower antioxidant at baseline. | 26605680 |
| Inflammation, Joint tenderness | Altered Intercellular Communication | Following rotation, loadings indicated that factor 1 comprised markers of peripheral inflammation: change in ESR, swollen joints, tender joints, and global health. | 26605992 |
| Inflammation | Altered Intercellular Communication | This distinct loading led to factor 1 being labeled peripheral inflammation. | 26605992 |
| Pain Distress Question, Inflammation, Fatigue | Altered Intercellular Communication | Conversely, factor 2 comprised change in pain, fatigue, and global health and an absence of peripheral inflammation markers and was therefore labeled central inflammation. | 26605992 |
| Pain Distress Question, Inflammation, Fatigue | Altered Intercellular Communication | Following anti-TNF therapies, reductions in fatigue and pain appear to reflect improvements in central, rather than peripheral, inflammation. | 26605992 |
| Inflammation | Altered Intercellular Communication | This may result in prolonged survival of P gingivalis, possibly driving autoantibody formation and a self-perpetuating loop of chronic inflammation. | 26606260 |
| Lymphoma | Altered Intercellular Communication | Cases were patients who developed lymphoma after diagnosis of primary SS and were mainly recruited through the Club Rhumatismes et Inflammation network. | 26606524 |
| Mucous Membrane, Inflammation | Altered Intercellular Communication | Short-chain fatty acids, mainly butyrate, are the major fuel source for the epithelium and their absence in the diverted tract may produce mucosal atrophy and inflammation. | 26607831 |
| Inflammation, Atrophic | Altered Intercellular Communication | To investigate whether the administration of sodium butyrate enemas (Naburen((c)), Promefarm, Italy) could prevent mucosal inflammation and atrophy and affect gene expression profiles after ileo/colostomy. | 26607831 |
| Osteoporosis | Altered Intercellular Communication | Age-related osteoporosis is thought to be determined by a number of intrinsic factors including genetics, hormonal changes, changes in levels of oxidative stress, or an inflammatory status associated with the aging process. | 26608808 |
| Refractory anemias, Inflammation | Altered Intercellular Communication | Thus, MBDA score may be a useful objective measure for identifying RA patients with active inflammation when CRP is low (1.0 mg/dl), including RA patients with concomitant FM. | 26608972 |
| ARCN1 gene, Inflammation | Altered Intercellular Communication | Increased serum TRAIL and DR5 levels correlated with lung function and inflammation in stable COPD patients. | 26609227 |
| ARCN1 gene, Inflammation, Chronic Obstructive Airway Disease | Altered Intercellular Communication | Chronic obstructive pulmonary disease (COPD) is associated with abnormal systemic inflammation, and apoptosis is one of the pathogenic mechanisms of COPD. | 26609227 |
| ARCN1 gene, Inflammation | Altered Intercellular Communication | Then, serum levels of TRAIL and DR5 in 57 COPD patients with 35 healthy controls were compared and correlated with lung function and systemic inflammation. | 26609227 |
| ARCN1 gene, Inflammation | Altered Intercellular Communication | Our results suggested that circulating TRAIL and DR5 increased in COPD patients and were associated with lung function and systemic inflammation in COPD. | 26609227 |
| Inflammation, Rheumatoid Arthritis | Altered Intercellular Communication | Increased inflammation in rheumatoid arthritis patients living where farm soils contain high levels of copper. | 26610397 |
| hearing impairment, Inflammation | Altered Intercellular Communication | Low-grade inflammation and microvessel pathology may be responsible for initiating or exacerbating some of the hearing loss associated with aging. | 26611434 |
| Inflammation | Altered Intercellular Communication | A shared etiological pathway may include a role of inflammation, alongside vascular determinants. | 26611434 |
| Inflammation, Acute appendicitis NOS (disorder) | Altered Intercellular Communication | CT of the abdomen and pelvis showed evidence of inflammation in the peritoneal soft tissues adjacent to an enlarged and thick-walled appendix, an appendicolith, no abscess formation and a slightly thickened caecum consistent with acute appendicitis. | 26611488 |
| Inflammation | Altered Intercellular Communication | The role of inflammation in the development of age-related diseases is widely recognized. | 26611787 |
| Inflammation | Altered Intercellular Communication | Our findings suggest that, in contrast to inflammation, immunosenescence appears to be highly dependent on HIV-infection and is only to a small extent associated with age-related parameters in well-treated HIV-infection. | 26611787 |
| Inflammation, Necrosis | Altered Intercellular Communication | The presence of zirconia particles results in frustrated digestion attempts by macrophages, liberation of inflammatory mediators, and necrosis leading to aseptic inflammation and osteolyses. | 26612414 |
| Cessation of life, Inflammation | Altered Intercellular Communication | Cellular inflammation, mainly consisting of functional cytotoxic T lymphocytes, was observed together with adipocyte cell death in human atria. | 26612579 |
| Inflammation | Altered Intercellular Communication | Murine IL-29 counterpart induces skin T-cell infiltration and inflammation in mice. | 26612594 |
| Inflammation, Fibrosis Assessment, Hallopeau-Siemens Disease | Altered Intercellular Communication | The purpose of this investigation was to elucidate the mechanisms of impaired wound healing and pseudosyndactyly occurring in RDEB patients by studying the role of known inflammation and fibrosis markers in RDEB pseudosyndactyly tissue. | 26612796 |
| Inflammation, Fibrosis Assessment, Epidermolysis Bullosa Dystrophica | Altered Intercellular Communication | Our results confirm inflammation and fibrosis in recessive dystrophic epidermolysis bullosa, especially in scars, suggesting major roles for these processes in pseudosyndactyly. | 26612796 |
| Necrotizing granulomatous inflammation, Tuberculosis | Altered Intercellular Communication | Open liver biopsy yielded chronic granulomatous inflammation compatible with pathological findings of tuberculosis infection. | 26613227 |
| Deficit, Neurodegenerative Disorders, Disease, Hypoperfusion | Altered Intercellular Communication | Both disorders appear to involve inflammation-related hyper-histaminemia, oxidative stress, autoimmune response, capsulothalamic hypoperfusion and BBB opening, and a deficit in melatonin metabolic availability; suggesting a risk of chronic neurodegenerative disease. | 26613326 |
| Inflammation, Joints | Altered Intercellular Communication | This study describes for the first time, in a large cohort of healthy subjects, the prevalence and location of US signs of joint inflammation and of structural damage in small joints of hands and feet. | 26613767 |
| Inflammation | Altered Intercellular Communication | This suggests that subclinical inflammation is present and that natural anticoagulant/thrombomodulin activity is important after transplant. | 26614396 |
| Inflammation, Depression, CTCAE | Altered Intercellular Communication | Coffee may reduce mortality risk by favorably affecting inflammation, lung function, insulin sensitivity, and depression. | 26614599 |
| Inflammatory abnormality of the eye, Dry Eye Syndromes, Congenital stationary cone dysfunction | Altered Intercellular Communication | Ocular surface inflammation is one of the primary mechanisms associated with dysfunctional tear syndrome (DTS), also known as dry eye disease. | 26615568 |
| Inflammation, Mental disorders, Traumatic injury | Altered Intercellular Communication | Particularly strong evidence indicates that childhood adversity and adulthood trauma exposure increase risk for physical and psychiatric disorders, and there is emerging evidence that inflammation may play a key role in these relationships. | 26616398 |
| Inflammation | Altered Intercellular Communication | Our study demonstrates the prevalence of trauma-related inflammation in the general population and suggests that childhood adversity and adulthood trauma are independently associated with elevated inflammation. | 26616398 |
| ARCN1 gene, Chronic Obstructive Airway Disease | Altered Intercellular Communication | Neutrophilic inflammation plays a causal role in Chronic Obstructive Pulmonary Disease (COPD). | 26616678 |
| ARCN1 gene, Inflammation | Altered Intercellular Communication | It was thus reasoned that doxycycline may attenuate neutrophil-mediated inflammation in COPD. | 26616678 |
| Inflammation | Altered Intercellular Communication | In order to exclude inflammation by bacterial colonisation patients must have 2 negative sputum cultures in the previous year. | 26616678 |
| Inflammation, Hypertension, CTCAE | Altered Intercellular Communication | It has been observed from the experiment which was designed on the basis of the correlation between inflammation reaction and essential hypertension that the content of urine UMOD protein of essential hypertension patients who is in stage I was (28.71 +- 10.53) mg/24 h and when compared with the control group's content (30.15 +- 14.10 mg/24 h), the difference was not obviously; The content of urine UMOD protein of essential hypertension patients who's in stage II and III was (18.24 +- 6.12) mg/24 h and (9.43 +- 3.16) mg/24 h, respectively, which were obviously lower than that of the control group (P<0.01). | 26617860 |
| Malignant neoplasm of urinary bladder, Inflammation, Carcinoma | Altered Intercellular Communication | Their bladder mucosal tissues were taken from the random biopsy of bladder cancer suspected patients without any finding such as inflammation or carcinoma in situ. | 26617941 |
| Inflammation, Acute Coronary Syndrome, GDC AJCC Clinical Stage Terminology | Altered Intercellular Communication | Inflammation has gained a pivotal role in the pathophysiology of Acute Coronary Syndrome (ACS). | 26618233 |
| Inflammation, Pancreatic carcinoma | Altered Intercellular Communication | Vagal nerve activity predicts overall survival in metastatic pancreatic cancer, mediated by inflammation. | 26618335 |
| Inflammation | Altered Intercellular Communication | Here we describe how different sialylation statuses of IgG autoantibodies contribute to the complex inflammatory network that regulates chronic inflammation. | 26618514 |
| Inflammation, Non-Small Cell Lung Carcinoma | Altered Intercellular Communication | Studies suggest that tumour-infiltrating lymphocytes (TILs) and inflammation markers have independent roles in non-small cell lung cancer (NSCLC), but the relationship between the two pronostic factors remains unclear. | 26619201 |
| Inflammation, Non-Small Cell Lung Carcinoma | Altered Intercellular Communication | Increased CD3+ and low CD5+ was observed in patients with poor prognosis; the two molecules were correlated with NLR, suggesting that inflammation might be used as improve therapeutic efficacy to immunotherapy for advanced NSCLC. | 26619201 |
| Inflammation, Immune System Diseases | Altered Intercellular Communication | Importantly, exercise did not exacerbate systemic inflammation or immune dysfunction; intradialytic exercise was well tolerated. | 26619202 |
| Inflammation, 4-hydroxy-2-oxovalerate aldolase activity, Joint tenderness | Altered Intercellular Communication | The higher frequency of joint tenderness in erosive HOA was at least partly explained more structural damage and inflammation. | 26620088 |
| hyperthermia treatment, Inflammation, Intracranial Hemorrhage, Intracranial Hypertension, Hypoxia, Cerebral Edema, Hypotension, CTCAE, Hypothermia due to exposure, Shock, Brain Injuries | Altered Intercellular Communication | Secondary brain injury occurs several hours or days after primary brain injury and is the result of factors including shock, systemic hypotension, hypoxia, hypothermia or hyperthermia, intracranial hypertension, cerebral oedema, intracranial bleeding or inflammation. | 26620118 |
| Inflammation | Altered Intercellular Communication | The study data indicate that inflammation is the most important cause of secondary insults. | 26620118 |
| Inflammation, Telangiectasis, Raynaud Phenomenon, CREST Syndrome, Sclerodactyly, Calcinosis, Laryngitis | Altered Intercellular Communication | The second patient was a 67-year-old woman with severe vocal fold inflammation related to laryngitis and calcinosis, Raynaud's phenomenon, esophagean dysmotility, sclerodactyly, and telangiectasia (CREST) syndrome. | 26620260 |
| Inflammation | Altered Intercellular Communication | YKL-40 is an extracellular matrix glycoprotein with a significant role in tissue inflammation and remodeling. | 26620310 |
| Airway structure | Altered Intercellular Communication | Airway inflammation was assessed with the fraction of exhaled nitric oxide (FeNO) and participants exhaled at various exhalation flows to determine alveolar and bronchial NO. | 26620577 |
| Airway structure, Obesity | Altered Intercellular Communication | Obesity does not influence airway inflammation as measured by FeNO. | 26620577 |
| Inflammation, Atherosclerosis | Altered Intercellular Communication | Positive association of plasma sCD36 with insulin resistance has been reported, and it has been proposed that sCD36 might represent a marker of macrophage activation and inflammation leading to atherosclerosis. | 26620683 |
| Inflammation | Altered Intercellular Communication | Our findings confirmed a central role for inflammation and proteases in plaque instability, and highlighted haemoglobin metabolism and bone resorption as important pathways. | 26620734 |
| Inflammation, Calcinosis | Altered Intercellular Communication | Subgroup analysis suggested prolonged inflammation following the symptoms of plaque instability and calcification as a possible stabilizing mechanism by statins. | 26620734 |
| Inflammation | Altered Intercellular Communication | HO-1 (3.91 vs. 5.67; p < 0.05) and HO-2 (1.06 vs. 1.37; p < 0.05) were significantly reduced in patients with high intra-prostatic inflammation (Irani score >=4). | 26621207 |
| Inflammation | Altered Intercellular Communication | MetS-induced inflammation may play a key role in BPH. | 26621207 |
| Osteomyelitis, Inflammation, Necrosis | Altered Intercellular Communication | Articular MRI showed inflammation and necrosis of both knees and ankles, and left hip and right elbow (compatible with osteomyelitis). | 26621903 |
| Inflammation, Neoplasms | Altered Intercellular Communication | Imaging findings of residual cervical tumor after chemoradiotherapy can closely resemble those of post-irradiation inflammation. | 26622060 |
| Inflammation | Altered Intercellular Communication | Eleven out of 41 (27%) patients showed inflammation with false positive post-chemoradiotherapy MRI and 1/41 (2%) had a false negative post-chemoradiotherapy MRI. | 26622060 |
| Inflammation, Neoplasms | Altered Intercellular Communication | The differentiation of residual tumor from post-irradiation inflammation with early post- chemoradiotherapy MRI (within 28-60 days) is difficult with a high risk of false positive results. | 26622060 |
| Inflammation, Kidney Diseases | Altered Intercellular Communication | The progression of kidney disease is significantly associated with inflammation, which could in the future be useful in prognostic and therapeutic purposes. | 26622082 |
| Inflammation, Chronic Kidney Diseases, Cardiovascular Diseases | Altered Intercellular Communication | Connection of CKD with inflammation and proven connection of inflammation with cardiovascular risk indicates the potential value of some biomarkers, which could in the future identify as predictors of outcome and could have the benefit in the early diagnosis and treatment of cardiovascular disease in CKD. | 26622082 |
| Granulomatous inflammation, Sarcoidosis, Non-necrotizing granulomatous inflammation | Altered Intercellular Communication | The biopsy specimen exhibited non-caseating, granulomatous inflammation and many multinucleated giant cells, strongly suggesting sarcoidosis. | 26624970 |
| Coinfection | Altered Intercellular Communication | HIV co-infection (aOR=3.44, p<0.001) and hormonal contraception (aOR=1.97, p=0.007) were associated with increased HPV prevalence. | 26625088 |
| Inflammation, Autoimmune hemolytic anemia | Altered Intercellular Communication | Laboratory tests show signs of autoimmune hemolytic anemia, elevated liver function tests, and moderate laboratory signs of inflammation. | 26625239 |
| Inflammation | Altered Intercellular Communication | Pathological changes due to inflammation were observed in the biopsy and esophagography. | 26625471 |
| Inflammation, Diabetic Retinopathy | Altered Intercellular Communication | Altered circulating mitochondrial DNA and increased inflammation in patients with diabetic retinopathy. | 26625720 |
| Diabetic Retinopathy, Inflammation | Altered Intercellular Communication | Our data show that circulating MtDNA levels are independently associated with diabetic retinopathy, showing an increase in DR-m and decrease in DR-s with a parallel increase in MtDNA damage and inflammation. | 26625720 |
| Inflammation, Diabetic Retinopathy, Diabetes Mellitus | Altered Intercellular Communication | Hyperglycemia-induced changes in MtDNA in early diabetes may contribute to inflammation and progression of diabetic retinopathy. | 26625720 |
| PROS1 gene, Inflammation | Altered Intercellular Communication | In addition, flare of joint inflammation in PsA patients has also been reported. | 26626908 |
| Inflammation, Chronic Kidney Diseases | Altered Intercellular Communication | In CKD, interleukin-6 and hypersensitive C-reactive protein are known to be used for the evaluation of inflammation and serum levels increase with decreased creatinine clearance. | 26627016 |
| Inflammation, hepcidin | Altered Intercellular Communication | Inflammation related hepcidin and NGAL weakly correlated with creatinine clearance. | 26627016 |
| Inflammation, hepcidin, Chronic Kidney Diseases | Altered Intercellular Communication | Our results demonstrated that serum NGAL and hepcidin levels might be valuable for the evaluation of inflammation in CKD, and these new inflammation parameters are not related through iron metabolism. | 26627016 |
| hepcidin | Altered Intercellular Communication | Neutrophil gelatinase-associated lipocalin (NGAL) and hepcidin are also considered to be effective in the assessment of inflammatory conditions. | 26627016 |
| Genus Axis, HIV Infections | Altered Intercellular Communication | Inflammation Perturbs the IL-7 Axis, Promoting Senescence and Exhaustion that Broadly Characterize Immune Failure in Treated HIV Infection. | 26627102 |
| Intestinal metaplasia, Inflammation, Atrophic | Altered Intercellular Communication | In histopathological evaluation of biopsy specimens according to Sydney criteria, chronic inflammation, activity, atrophy, intestinal metaplasia and helicobacter pylori parameters were used. | 26627512 |
| Inflammation | Altered Intercellular Communication | The degree of activation and severity of inflammation increased significantly with increasing helicobacter pylori positivity(r=0.459'p<0.0001; r=0.475'p<0.0001). | 26627512 |
| Inflammation | Altered Intercellular Communication | There was also a statistically significant correlation between severity of inflammation and activation and the number of eosinophils (r=0.313;p=0.002;r=0.245;p=0.016). | 26627512 |
| Respiratory Distress Syndrome, Adult, Inflammation, Respiratory Distress Syndrome, Newborn | Altered Intercellular Communication | The development of acute respiratory distress syndrome (ARDS) is associated with dys-regulated inflammation. | 26627982 |
| Interstitial inflammation | Altered Intercellular Communication | Specifically, hESC-MSC treatment prevented disease-associated interstitial inflammation, protein cast deposition, and infiltration of CD3(+) lymphocytes in the kidneys. | 26628350 |
| Inflammation, Liver carcinoma, Fibrosis Assessment, Fatty degeneration, Non-alcoholic Fatty Liver Disease, Liver Cirrhosis | Altered Intercellular Communication | Nonalcoholic fatty liver disease (NAFLD) represents a spectrum of disorders from simple steatosis to inflammation leading to fibrosis, cirrhosis, and even hepatocellular carcinoma. | 26629307 |
| Inflammation, Damage | Altered Intercellular Communication | No correlation was observed between the intensity and type of dermal inflammation and the degree of epidermal damage or the culprit drug. | 26630685 |
| Inflammation, Bladder Adenocarcinoma | Altered Intercellular Communication | Cystoscopy and biopsy revealed an adenocarcinoma of the anterior bladder and stoma with extensive associated mucin production and a background of acute and chronic inflammation. | 26630940 |
| Inflammation, Hypertension, CTCAE | Altered Intercellular Communication | High-dose omega-3 fatty acids did not reduce arterial PWV or markers of inflammation among patients within a Latino-predominant population with hypertension. | 26631058 |
| Inflammation, proIslet peptide, human | Altered Intercellular Communication | Apigenin Attenuates Inflammation in Experimentally Induced Acute Pancreatitis-Associated Lung Injury. | 26631908 |
| Conjunctivitis | Altered Intercellular Communication | Treatment with doxycyline, dapsone, and mycophenolate mofetil was unsuccessful and treatment with rituximab has led to partial remission of the conjunctival inflammation. | 26632795 |
| Inflammation, Neoplasms | Altered Intercellular Communication | Infiltrating neutrophils, lymphocytes, macrophages, and cytokines constitute a state of chronic inflammation within the tumor microenvironment. | 26632898 |
| Inflammation | Altered Intercellular Communication | Tartrate-resistant acid phosphatase 5a (TRACP5a) protein, a novel product of activated macrophage, is postulated to be a biomarker for systemic inflammatory burden in states of chronic inflammation. | 26632898 |
| Inflammation, Diabetes Mellitus, Non-Insulin-Dependent | Altered Intercellular Communication | High levels of serum long chain saturated fatty acids (LCSFAs) have been associated with inflammation in type 2 diabetes. | 26633920 |
| Gastrointestinal inflammation | Altered Intercellular Communication | Faecal (f-) calprotectin is a biomarker of intestinal inflammation. | 26634305 |
| ARCN1 gene, Chronic Obstructive Airway Disease, Carcinoma of lung, Airway structure | Altered Intercellular Communication | Asthma and COPD (chronic obstructive pulmonary disease) lead to persistent airway inflammation and are associated with lung cancer. | 26634452 |
| Inflammation, Fibrosis Assessment, Injury of liver | Altered Intercellular Communication | Primary outcome measures include change in hepatic injury (fibrosis and inflammation) and liver fat. | 26635079 |
| Inflammation, Atherosclerosis, Acute Coronary Syndrome, GDC AJCC Clinical Stage Terminology, vascular inflammations | Altered Intercellular Communication | Vascular inflammation plays a key role in the development of atherosclerosis and acute coronary syndrome (ACS), and pentraxin 3 (PTX3) is one of several novel, promising markers of inflammation. | 26635361 |
| atherosclerotic | Altered Intercellular Communication | Serum cyclin-dependent kinase 9 is a potential biomarker of atherosclerotic inflammation. | 26636538 |
| Inflammation, Atherosclerosis | Altered Intercellular Communication | Altogether, These findings indicate that CDK9 represent an important role for inflammation in the pathogenesis of atherosclerosis. | 26636538 |
| atherosclerotic | Altered Intercellular Communication | It may be a potential biomarker of atherosclerotic inflammation and offer insights into the pathophysiology and targeted therapy for atherosclerotic CAD. | 26636538 |
| Inflammation | Altered Intercellular Communication | Inflammation is a condition stemming from complex host defense and tissue repair mechanisms, often simply characterized by plasma levels of a single acute reactant. | 26636573 |
| HD Term Type, Inflammation | Altered Intercellular Communication | The role of inflammation and the significance of non-neuronal involvement in HD pathogenesis suggest anti-inflammatory therapeutics may offer important opportunities in treating HD. | 26636579 |
| Inflammation, Disease, Candida (fungus) | Altered Intercellular Communication | The proof of multiresistant pathogens or Candida, as well as the level of inflammation markers, have an impact on the prognosis of the underlying tumor disease. | 26637394 |
| Inflammation, Chronic sinusitis, Craniosynostosis | Altered Intercellular Communication | Fungus-driven inflammation is proposed to play an important role in the pathogenesis of chronic rhinosinusitis (CRS). | 26637583 |
| Inflammation, AHSP gene, Atrial Fibrillation by ECG Finding | Altered Intercellular Communication | Inflammation plays a prominent role in the etiology of the early recurrence of atrial fibrillation (ERAF). | 26638872 |
| Ischemia, Metabolic Diseases, Inflammation, Demyelination, Neoplasms, Communicable Diseases, Phenylketonurias | Altered Intercellular Communication | Cerebral white matter lesions (CWMLs), identified in magnetic resonance imaging (MRI), are related to various clinical conditions including ischemia, inflammation, demyelination, infection, a tumor, and metabolic disorders such as phenylketonuria. | 26639091 |
| Cholesteatoma, bone destruction, Inflammation | Altered Intercellular Communication | TLR4 drives the pathogenesis of acquired cholesteatoma by promoting local inflammation and bone destruction. | 26639190 |
| Inflammation, Acute-On-Chronic Liver Failure, CRNKL1 wt Allele | Altered Intercellular Communication | Activation of liver macrophages plays a key role in liver and systemic inflammation and may be involved in development and prognosis of acute-on-chronic liver failure (ACLF). | 26639396 |
| Cerebral Amyloid Angiopathy, Inflammation | Altered Intercellular Communication | We report a biomarker and genetic evaluation of four patients with cerebral amyloid angiopathy-related inflammation (CAA-ri) treated with corticosteroids. | 26639966 |
| Inflammation, Data types - Address, Memory impairment | Altered Intercellular Communication | These results suggest that OCGP may prevent memory impairment in AD by inhibiting Ab accumulation and inflammation in the brain. | 26639976 |
| Inflammation, Observation Method - Coagulation | Altered Intercellular Communication | Elevated Biomarkers of Inflammation and Coagulation in Patients with HIV Are Associated with Higher Framingham and VACS Risk Index Scores. | 26641655 |
| Inflammation, Observation Method - Coagulation, Psychological suppression | Altered Intercellular Communication | Despite viral suppression and immunological stability, biomarkers of inflammation and coagulation remain elevated in a significant number of patients with HIV and are associated with higher scores on risk stratification indices. | 26641655 |
| ARCN1 gene, Inflammation | Altered Intercellular Communication | Haemophilus influenzae frequently colonizes the airways of COPD patients, where it enhances inflammation. | 26642881 |
| Alzheimers Disease", Data types - Address | Altered Intercellular Communication | Alzheimer's disease (AD) affects many central nervous structures and neurotransmitter systems. | 26643357 |
| Inflammation, Atherosclerosis | Altered Intercellular Communication | Inflammation and leukocyte infiltration are hallmarks of atherosclerosis. | 26643521 |
| Mouth Diseases, Gingivitis, Periodontitis, bone destruction | Altered Intercellular Communication | Chronic periodontitis is an oral disorder characterized with gingival inflammation and bone destruction. | 26643602 |
| Inflammation, Units Of Measure - Siemens, Metabolic Syndrome X | Altered Intercellular Communication | Second, MHO was defined as being free of all metabolic syndrome criteria, insulin resistance and inflammation. | 26643813 |
| Inflammation, Units Of Measure - Siemens | Altered Intercellular Communication | Associations between dietary components and MHO were weak and inconsistent, while physical activity and inflammation were not associated with MHO in male and female adolescents for both definitions (p > 0.05). | 26643813 |
| Inflammation | Altered Intercellular Communication | Zinc dyshomeostasis may lead to an augmented production of proinflammatory cytokines promoting chronic inflammation and increasing the susceptibility to age-related diseases. | 26643924 |
| Inflammation, Malignant Neoplasms | Altered Intercellular Communication | C-reactive protein (CRP), a biomarker of inflammation, may correlate with prognosis in several malignancies. | 26643974 |
| FAM126A gene | Altered Intercellular Communication | Early postoperative serum CRP may serve as a useful inflammation-based biomarker of outcome in liver transplant patients with HCC. | 26643974 |
| Communicable Diseases, Carcinogenesis, Inflammation, Infective vaginitis | Altered Intercellular Communication | Vaginal infections may affect susceptibility to and clearance of human papillomavirus (HPV) infection and chronic inflammation has been linked to carcinogenesis. | 26644228 |
| Kidney Failure, Chronic, Inflammation, Malnutrition, Diabetes Mellitus, Systemic disease, Hypertension, CTCAE | Altered Intercellular Communication | In this cohort of incident end-stage renal disease patients with diabetes, poor glycemic control was independently associated with younger age, Native American race, Hispanic ethnicity, higher body mass index, and clinical risk factors including atherogenic lipoprotein profile, hypertension, inflammation, and markers indicative of malnutrition and a more serious systemic disease. | 26645204 |
| Sepsis, Inflammation | Altered Intercellular Communication | A Molecular Host Response Assay to Discriminate Between Sepsis and Infection-Negative Systemic Inflammation in Critically Ill Patients: Discovery and Validation in Independent Cohorts. | 26645559 |
| Sepsis, Inflammation | Altered Intercellular Communication | Systemic inflammation is a whole body reaction having an infection-positive (i.e., sepsis) or infection-negative origin. | 26645559 |
| Inflammation, Eating | Altered Intercellular Communication | EAT in CAD is characterized by changes in the regulation of metabolism and inflammation with miR-103-3p/CCL13 pair as novel putative actors in EAT function and CAD. | 26645979 |
| Necrotizing granulomatous inflammation | Altered Intercellular Communication | Detailed cytological examination revealed necrotizing granulomatous inflammation as most common pattern (43%). | 26646425 |
| Inflammation, anatomical bulb, conjunctiva | Altered Intercellular Communication | Conjunctival sensation was tested by Cochet-Bonnet aesthesiometer in four quadrants of the bulbar conjunctiva plus the area(s) of active or previously active inflammation; sensation was compared with the contralateral eye. | 26647348 |
| Inflammation, Scleritis, conjunctiva | Altered Intercellular Communication | Conjunctival sensation is decreased in areas of previously active inflammation from scleritis. | 26647348 |
| Inflammation, Herpetic Gastritis, conjunctiva | Altered Intercellular Communication | Eyes with herpetic scleritis had reduced conjunctival sensation, even in areas without previous active inflammation. | 26647348 |
| Inflammation, Inflammatory disorder | Altered Intercellular Communication | Asthma is a chronic inflammatory disorder of the airways where bacteria may act as protagonists of chronic inflammation. | 26647445 |
| Airway structure | Altered Intercellular Communication | Little is known about the relation of airway inflammation to the presence of specific bacterial taxa. | 26647445 |
| Crohn Disease, Inflammation, Spondylitis | Altered Intercellular Communication | Distinct immune signatures in the colon of Crohn's disease and ankylosing spondylitis patients in the absence of inflammation. | 26647966 |
| Inflammatory Bowel Diseases, Crohn Disease, Inflammation | Altered Intercellular Communication | Crohn's disease (CD) is an inflammatory bowel disease characterized by patchy inflammation of the gastrointestinal tract. | 26647966 |
| Inflammation, Spondylitis | Altered Intercellular Communication | Ankylosing spondylitis (AS) is primarily characterized by inflammation of the lower vertebral column, and many patients with AS present with inflammatory gut symptoms. | 26647966 |
| Bone Diseases, Inflammation, Acidosis | Altered Intercellular Communication | The evaluation of acid-basic status should be routinely implemented in dialysis patients by considering the negative effects of acidosis on the nutritional status, inflammation and bone disease. | 26648495 |
| Inflammation, thromboembolic, Necrotizing, Cerebrovascular accident | Altered Intercellular Communication | The release of necrotizing factor and interleukins may cause inflammation of the endothelial lining, creating a prothrombotic surface that triggers thromboembolic events, including stroke. | 26648966 |
| Inflammation, Sarcoidosis, Pulmonary | Altered Intercellular Communication | Pulmonary sarcoidosis is classically defined by T-helper (Th) cell type 1 inflammation (e.g., IFN-g production by CD4(+) effector T cells). | 26649486 |
| vascular inflammations | Altered Intercellular Communication | In all three patients receiving interleukin-6 blockade, laboratory markers and clinical scores normalized despite persistent vascular inflammation in one patient which was disclosed by MRI. | 26649990 |
| Inflammation, "Alzheimers Disease", Data types - Address | Altered Intercellular Communication | Inflammation in the brain is a prominent feature in Alzheimer's disease (AD). | 26650044 |
| Inflammation, Failure (biologic function) | Altered Intercellular Communication | Recent studies suggest that chronic inflammation can be a consequence of failure to resolve the inflammation. | 26650044 |
| levamisole, Inflammation, Data types - Address | Altered Intercellular Communication | Resolution of inflammation is mediated by a family of lipid mediators (LMs), and the levels of these specialized pro-resolving mediators (SPMs) are reduced in the hippocampus of those with AD. | 26650044 |
| Inflammation, Calcification of coronary artery, Cardiovascular Diseases, Microalbuminuria, Endothelial dysfunction, Diabetes Mellitus, Non-Insulin-Dependent | Altered Intercellular Communication | Markers of inflammation and endothelial dysfunction are associated with incident cardiovascular disease, all-cause mortality, and progression of coronary calcification in type 2 diabetic patients with microalbuminuria. | 26651261 |
| Inflammation, SLC25A20 gene, Cardiovascular Diseases, Microalbuminuria, Cyclophosphamide/Vincristine/Dacarbazine Regimen, Coronary Artery Disease, Endothelial dysfunction, Diabetes Mellitus, Non-Insulin-Dependent | Altered Intercellular Communication | We evaluated markers of inflammation and endothelial dysfunction and their associations with incident cardiovascular disease (CVD), all-cause mortality and progression of coronary artery calcium (CAC) in patients with type 2 diabetes (T2D) and microalbuminuria but without known coronary artery disease (CAD). | 26651261 |
| Inflammation, Endothelial dysfunction | Altered Intercellular Communication | Higher composite z-scores including all markers of inflammation and endothelial dysfunction were associated with CVD and all-cause mortality (p<=0.008). | 26651261 |
| Inflammation, SLC25A20 gene, Microalbuminuria, Endothelial dysfunction, Diabetes Mellitus, Non-Insulin-Dependent | Altered Intercellular Communication | In patients with T2D and microalbuminuria without known CAD and receiving multifactorial treatment, biomarkers of inflammation and endothelial dysfunction were independently associated with CVD, all-cause mortality and CAC progression. | 26651261 |
| Inflammation, Gastrointestinal symptom, Chronic Kidney Diseases, Hypoalbuminemia | Altered Intercellular Communication | Gastrointestinal symptoms, inflammation and hypoalbuminemia in chronic kidney disease patients: a cross-sectional study. | 26651991 |
| Inflammation, Chronic Kidney Diseases | Altered Intercellular Communication | Our goal in this paper is to study how GI symptoms relate to serum albumin levels in CKD, especially in the context of and compared with inflammation. | 26651991 |
| Inflammation, Chronic Kidney Diseases | Altered Intercellular Communication | But our data do not support GI symptoms/decreased protein intake or inflammation as being the main determinants of serum albumin level in CKD patients. | 26651991 |
| HMGCL gene, Inflammation, Appendicitis, CTCAE | Altered Intercellular Communication | A small increased risk of HL following appendicitis (rather than appendectomy per se) could reflect a true association, or shared susceptibility to infection/inflammation among individuals prone to develop HL. | 26652908 |
| Arthritis | Altered Intercellular Communication | Two types of self-reported symptoms, chronic joint inflammation and worn out joints, were used for the analyses. | 26653129 |
| Blindness, Communicable Diseases, Inflammation | Altered Intercellular Communication | The mass delivery of antibiotics is highly beneficial for the clearance of infection, inflammation and prevention of subsequent scarring, but needs to be supplemented with sustained reductions in transmission and surgery to consider realistically the elimination of blindness by the year 2020. | 26653262 |
| Inflammation, Rathke Cleft Cysts, Rupture, Aneurysm | Altered Intercellular Communication | The severe inflammation around the vasculature after rupture of the Rathke cleft cyst might have been involved in aneurysm formation. | 26654927 |
| Eye pain, Blurred vision, anatomical bulb, Intraocular inflammation | Altered Intercellular Communication | None of the patients complained of blurred vision, ocular pain, or bulbar injection at any of the follow-up visits, nor was intraocular inflammation noted. | 26655620 |
| Airway structure | Altered Intercellular Communication | Blocking b-catenin expression with a specific siRNA attenuated airway inflammation and airway remodeling. | 26655831 |
| Inflammation, Primary malignant neoplasm, Neoplasms | Altered Intercellular Communication | Growing evidence showed that inflammation response plays an important role in cancer development and progression, and absolute lymphocyte count (ALC), absolute monocyte count (AMC), and lymphocyte to monocyte ratio (LMR) have been used as parameters of systemic inflammation in several tumors. | 26656374 |
| Inflammation, Malignant Neoplasms | Altered Intercellular Communication | It has been reported nutritional status and systemic inflammation were associated with the outcome of patients with malignancies. | 26656866 |
| ARCN1 gene, Inflammation, Chronic Obstructive Airway Disease | Altered Intercellular Communication | Based on the knowledge that chronic obstructive pulmonary disease (COPD) starts in the small airway epithelium, we hypothesized that chronic inflammation modulates peripheral exhaled particle SP-A and albumin levels. | 26656890 |
| Inflammation, Observation Method - Coagulation, Injury of kidney | Altered Intercellular Communication | Acute kidney injury in high-risk cardiac surgery patients: roles of inflammation and coagulation. | 26657082 |
| Inflammation, Kidney Failure, Acute | Altered Intercellular Communication | Cardiopulmonary bypass elicits coagulation and inflammation activation and oxidative stress, all involved in AKI but never simultaneously assessed. | 26657082 |
| Communicable Diseases, FBN2 wt Allele, Inflammation | Altered Intercellular Communication | Chronic inflammation and oxidative stress induced by liver fluke, Opisthorchis viverrini, infection has been recognized as the major cause of CCA in this area. | 26657242 |
| Inflammation | Altered Intercellular Communication | Removal should be considered, however, if there is a risk of it becoming infected due to implantation-induced inflammation. | 26657524 |
| Electrocardiogram: myocardial infarction (finding) | Altered Intercellular Communication | Variants of the Coagulation and Inflammation Genes Are Replicably Associated with Myocardial Infarction and Epistatically Interact in Russians. | 26658659 |
| Inflammation | Altered Intercellular Communication | This applies as well to the genes involved in inflammation and coagulation processes, which play a crucial role in the disease etiopathogenesis. | 26658659 |
| Inflammation, Malignant Neoplasms | Altered Intercellular Communication | Simvastatin, an HMG-coA reductase inhibitor, is known to attenuate inflammation and prevent certain cancers. | 26658759 |
| Inflammation | Altered Intercellular Communication | Application of the proposed Consensus Conference grading revealed inflammatory activity in all patients with mild (33 %), moderate (44 %), or severe inflammation (23 %). | 26659079 |
| Communicable Diseases, Inflammation | Altered Intercellular Communication | Adequate suppression of cardiac glucose metabolism increases the interpretability and diagnostic reliability of (18)F-FDG PET studies performed to detect cardiac inflammation and infection. | 26659348 |
| Communicable Diseases, Inflammation | Altered Intercellular Communication | Group 1 included oncologic indications, and groups 2 and 3 infection or inflammation detection. | 26659348 |
| Communicable Diseases, Inflammation | Altered Intercellular Communication | Cardiac segments for which inflammation or infection foci had been confirmed on other imaging modalities were excluded from the analysis. | 26659348 |
| Inflammation, Kidney Diseases, Cardiovascular Diseases | Altered Intercellular Communication | Thus, IS may play an important role in the development of cardiovascular disorders in kidney diseases during inflammation by increasing endothelial expression of E-selectin. | 26659566 |
| Acute Kidney Injury, CTCAE, Kidney Failure, Acute, Kidney Diseases, Cardiovascular Diseases | Altered Intercellular Communication | Uremic toxins are considered a risk factor for cardiovascular disorders in kidney diseases, but it is not known whether, under inflammatory conditions, they affect adhesion molecule expression on endothelial cells, which may play a critical role in acute kidney injury (AKI). | 26659566 |
| ARCN1 gene, Inflammation, Pulmonary Emphysema | Altered Intercellular Communication | Long-term benefits of ICS on lung function decline in patients with moderate-to-severe COPD are most pronounced in patients with fewer packyears, and less severe emphysema and inflammation. | 26659582 |
| Inflammation | Altered Intercellular Communication | Systemic and intestinal levels of factor XIII-A: the impact of inflammation on expression in macrophage subtypes. | 26660730 |
| Gastrointestinal inflammation | Altered Intercellular Communication | The objective was to evaluate the consequences of intestinal inflammation on resident mucosal macrophages, focusing on the level and distribution of FXIII-A. | 26660730 |
| Gastrointestinal inflammation, Ulcerative Colitis | Altered Intercellular Communication | Intestinal inflammation in UC induces loss of M2 macrophages with subsequent loss of FXIII-A synthesis. | 26660730 |
| Sepsis | Altered Intercellular Communication | Loss of plasma FXIII-A has been reported after surgery, sepsis, and inflammatory conditions. | 26660730 |
| Inflammation, Calcified (qualifier), Cardiovascular Diseases | Altered Intercellular Communication | Lower levels of ES and OPN in physically active patients might be a sign of increased angiogenesis and decreased inflammation and calcifying activity and therefore contribute to the understanding of the damaging effect of physical inactivity in cardiovascular disease. | 26661073 |
| Inflammation, Sample Size Calculation, Systemic Scleroderma | Altered Intercellular Communication | Cathepsin L (CTSL) is a lysosomal proteolytic enzyme involved in inflammation and vascular and extracellular matrix remodelling, which are the three cardinal pathological events associated with systemic sclerosis (SSc). | 26661692 |
| Airway structure, Bronchial Hyperreactivity | Altered Intercellular Communication | (2) To assess the relationships between sputum clusterin levels and airway inflammation, pulmonary function, and bronchial hyperresponsiveness. | 26661728 |
| Airway structure, Asthma | Altered Intercellular Communication | Clusterin may be a marker that reflects airway inflammation and severity of symptoms, and it can be used in the assessment and management of childhood asthma. | 26661728 |
| Inflammation, GDC AJCC Clinical Stage Terminology, Atherosclerosis | Altered Intercellular Communication | These findings indicate that the decrease of the frequency of Treg cells in the peripheral blood of patients with ACS might destroy the balance of tolerance of the peripheral immune system and might activate inflammation, thus participating in the occurrence and development of the pathological processes of atherosclerosis. | 26662384 |
| Inflammation, Anemia, Chronic Kidney Diseases | Altered Intercellular Communication | After excluding 121 participants with three most common causes of anaemia (chronic kidney disease, inflammation, iron deficiency), anaemia was found in 4*7% of euthyroid participants. | 26662849 |
| Esophageal | Altered Intercellular Communication | No patient in histological remission showed symptom relapse, but half of patients with relapsing oesophageal inflammation were in clinical remission. | 26662868 |
| Inflammation, Acute Coronary Syndrome, GDC AJCC Clinical Stage Terminology | Altered Intercellular Communication | Inflammation in response to oxidized lipoproteins is thought to play a key role in acute coronary syndromes (ACS), but the pattern of immune activation has not been fully characterized. | 26663396 |
| Inflammation, Portal Vein Thrombosis | Altered Intercellular Communication | This case suggests that inflammation around the portal vein as a result of C. sinensis infection has the potential to evoke portal vein thrombosis. | 26663478 |
| Inflammation | Altered Intercellular Communication | Alteration of Urothelial Inflammation, Apoptosis, and Junction Protein in Patients with Various Bladder Conditions and Storage Bladder Symptoms Suggest Common Pathway Involved in Underlying Pathophysiology. | 26663690 |
| Inflammation, Urinary Tract Physiology, physiopathological | Altered Intercellular Communication | This study investigated urothelial dysfunction and chronic inflammation in the urothelium in different types of lower urinary tract dysfunction (LUTD), which causes bladder storage symptoms. | 26663690 |
| Inflammation | Altered Intercellular Communication | Increased urothelial inflammation and urothelial cell apoptosis seem to share common pathophysiologies of various LUTDs that cause similar bladder symptoms. | 26663690 |
| Prostate | Altered Intercellular Communication | Dramatic Enlargement of the Prostate due to Xanthogranulomatous Inflammation. | 26663733 |
| Adenocarcinoma, Inflammation, Prostate | Altered Intercellular Communication | Xanthogranulomatous inflammation of the prostate is a rare condition that can cause lower urinary tract symptoms and may be mistaken for adenocarcinoma. | 26663733 |
| Inflammation | Altered Intercellular Communication | We present a case of a 78-year-old man found to have a 318 g prostate secondary to xanthogranulomatous inflammation. | 26663733 |
| Complication Aspects, Keratitis, Uveitis | Altered Intercellular Communication | A diverse spectrum of ocular complications was observed with corneal inflammation and opacification in 77% followed by anterior uveitis in 65%. | 26663773 |
| Myocardial fibrosis, Inflammation | Altered Intercellular Communication | Tenascin-C (Tn-C) and matrix metalloproteinase-9 (MMP-9) are extracellular matrix proteins associated with myocardial fibrosis and wall remodeling because of inflammation. | 26663885 |
| ARCN1 gene, Inflammation | Altered Intercellular Communication | Severe COPD patients with LVDD showed a different inflammatory pattern, suggesting a link between low-grade inflammation and the presence of LVDD. | 26663885 |
| Exacerbation of asthma, Asthma, Inflammation, Respiratory Tract Infections | Altered Intercellular Communication | Respiratory infections are a major cause of asthma exacerbations where neutrophilic inflammation dominates and is associated with steroid refractory asthma. | 26663987 |
| Pachymeningitis, Inflammatory Myofibroblastic Tumor, Neurosarcoidosis | Altered Intercellular Communication | We report a case of a 55-year-old female who had probable isolated neurosarcoidosis based on magnetic resonance imaging findings of relapsing pachymeningitis with an inflammatory process in the apex of the right orbit and pseudotumor inflammation of the superior and lateral recti of the right eye. | 26666108 |
| Inflammation, Nasal Polyps, Chronic sinusitis | Altered Intercellular Communication | Toll-like receptor 3 (TLR3) is expressed in upper airways, however, little is known regarding whether Toll-like receptor 3 (TLR3) signals exert a regulatory effect on the pathogenesis of chronic rhinosinusitis with nasal polyps (CRSwNP), especially on eosinophilic inflammation. | 26666485 |
| Interstitial inflammation | Altered Intercellular Communication | An autopsy revealed diffuse interstitial inflammation of both lungs consistent with drug-induced inflammation. | 26666606 |
| Inflammation, Cardiovascular Diseases | Altered Intercellular Communication | Neutrophil to lymphocyte ratio (NLR) has emerged as a marker of inflammation in neoplastic and cardiovascular disorders. | 26666737 |
| Inflammation, Anorexia | Altered Intercellular Communication | Chronic inflammation of the stomach that results in the loss of appetite and, dysregulation of neuroendocrine hormones such as leptin, and ghrelin are the probable reasons of this negative association. | 26667121 |
| Inflammation, Anorexia | Altered Intercellular Communication | Chronic inflammation of the stomach that results in the loss of appetite and, dysregulation of neuroendocrine hormones such as leptin, and ghrelin are the probable reasons of this negative association. | 26667121 |
| Inflammation | Altered Intercellular Communication | We found a loss of CD4(+) T cell subset balance that was likely to promote a higher state of inflammation in IA, which may exacerbate the disease through a positive feedback loop. | 26667180 |
| Inflammation | Altered Intercellular Communication | Cryopyrin-associated periodic syndrome (CAPS) is a heterogeneous group of diseases characterized by excessive IL-1b release resulting in severe systemic and organ inflammation. | 26667214 |
| Inflammation, Atherosclerosis | Altered Intercellular Communication | Resistin is associated with inflammation, atherosclerosis and cardiovascular (CV) disease. | 26667298 |
| Inflammation, Malnutrition, Organ Dysfunction Scores | Altered Intercellular Communication | critical illness is characterized by a high degree of stress and accelerated degradation of proteins that cause malnutrition, systemic inflammation and organ dysfunction, with a significant association between albumin, ferritin and transferrin. | 26667743 |
| Inflammation, Ulcer | Altered Intercellular Communication | In fact, endoscopic, histological and endomicroscopic assessment demonstrated exacerbation of mucosal inflammation and ulcer formation upon anti-IL-6R therapy. | 26668517 |
| Ulcerative Colitis, Inflammatory disease of mucous membrane | Altered Intercellular Communication | Mechanistic studies revealed that tocilizumab treatment failed to suppress intestinal IL-6 production, impaired epithelial barrier function and induced production of pro-inflammatory cytokines such as TNF, IL-21 and IFN-g. Inhibition of IL-6 by tocilizumab had no clinical benefit in this patient with intractable ulcerative colitis and even led to exacerbation of mucosal inflammation. | 26668517 |
| Conjunctivitis, Strabismus | Altered Intercellular Communication | The MISS technique was similar to the fornix approach in the early postoperative period with respect to VA, conjunctival inflammation, and operating time in pediatric horizontal strabismus surgery. | 26669420 |
| Osteomyelitis, Inflammation, Fracture, Diabetes Mellitus | Altered Intercellular Communication | In this case report we present the dramatic course of a 64-year old female patient treated with five immediate post-extractive dental implants in the mandible, who developed osteomyelitis, which manifested initially as local peri-implant inflammation and progressed into a spontaneous jaw fracture, despite repeated surgical interventions and antibiotic courses over a 3-year period, until diabetes was diagnosed. | 26669550 |
| Pulmonary hemorrhage, Interstitial inflammation | Altered Intercellular Communication | Pulmonic interstitial inflammation gradually improved while resting the lung under ECMO support; however, effective ventilation volume decreased critically because a massive pulmonary hemorrhage occurred at 2 and 9 days after the initiation of ECMO. | 26670317 |
| Hematoxylin and eosin stain method, Inflammation, Synovitis | Altered Intercellular Communication | Two to three paraffin slides were used to quantify inflammation using haematoxylin and eosin (H&E) staining (synovitis score 0-9), and numbers of mast cells (per 10 high-power fields) using double immunofluorescence for CD117 and tryptase. | 26671522 |
| Autoimmune Diseases, Inflammation | Altered Intercellular Communication | Due to its crucial roles in inflammation and autoimmunity, STAT4 may have promise as an effective therapeutic target for axSpA. | 26671920 |
| Acute inflammation | Altered Intercellular Communication | It accurately differentiates patients who have chronic transmural (fibrotic) disease and thus may require an operation from those with acute inflammation, whose symptoms may improve with aggressive medical therapy alone. | 26672581 |
| Nephritis, Interstitial, Inflammation, Guinea (geographic area) | Altered Intercellular Communication | The granulomatous inflammation is rarely but often manifests as a form of a granulomatous interstitial nephritis (GIN) in the kidney. | 26674186 |
| Inflammation | Altered Intercellular Communication | Control of inflammation will inform the design of surface modification procedures to direct the immune response and enhance the success of implanted materials. | 26675126 |
| vascular inflammations, atherosclerotic | Altered Intercellular Communication | Chemokines appear to be involved in the development of these alterations given that they occur early in the atherosclerotic pathway as mediators of vascular inflammation. | 26675251 |
| Anemia, Sickle Cell, Inflammation, Thalassemia, Erythroblastosis, Fetal | Altered Intercellular Communication | Hemolytic diseases, such as sickle cell anemia and thalassemia, are characterized by enhanced release of hemoglobin and heme into the circulation, heme-iron loading of reticulo-endothelial system macrophages, and chronic inflammation. | 26675351 |
| Inflammation, Anemia, Sickle Cell | Altered Intercellular Communication | Taken together, our data suggest that therapeutic administration of hemopexin is beneficial to counteract heme-driven macrophage-mediated inflammation and its pathophysiologic consequences in sickle cell disease. | 26675351 |
| Inflammation, Hypomyelination, Neurologic Dysfunction | Altered Intercellular Communication | This leukodystrophy causes severe hypomyelination with progressive inflammation, leading to neurological dysfunctions and shortened life expectancy. | 26676415 |
| Sacroiliitis, Arthritis, Spondylitis, Enthesitis | Altered Intercellular Communication | Spondyloarthropathy (SpA) is a group of inflammatory conditions that include spondylitis, sacroiliitis, asymmetrical peripheral arthritis and enthesitis. | 26677159 |
| Inflammation, Asthma, Chronic sinusitis, Craniosynostosis | Altered Intercellular Communication | Chronic rhinosinusitis (CRS) and asthma describe inflammation of the upper and lower airway, respectively. | 26678021 |
| Inflammation | Altered Intercellular Communication | Our results suggest that NFkB, STAT1 and STAT3 underlie transcriptional changes and chronic inflammation in the aging human kidney. | 26678048 |
| Non-alcoholic Fatty Liver Disease | Altered Intercellular Communication | Follicle-stimulating hormone is associated with non-alcoholic fatty liver disease in Chinese women over 55 years old. | 26678239 |
| Inflammation, Atrial Fibrillation by ECG Finding, Cardiovascular Diseases | Altered Intercellular Communication | Inflammation has been associated with cardiovascular disease and the burden of atrial fibrillation (AF). | 26678637 |
| Inflammation, Chronic sinusitis, Craniosynostosis | Altered Intercellular Communication | Diagnostic nasal endoscopy is a routine measure of sinonasal inflammation in patients with chronic rhinosinusitis (CRS). | 26678860 |
| prostatitis | Altered Intercellular Communication | We sought to determine the influence of young adult-onset IM on the prostate by measuring prostate-specific antigen (PSA) as a marker of prostate inflammation/damage among U.S. military members. | 26678984 |
| Communicable Diseases, Inflammation, Prostate | Altered Intercellular Communication | To explore the specificity of our findings for prostate as opposed to systemic inflammation, we performed a post hoc comparison of other infectious disease cases without genitourinary involvement (n = 90) and controls (n = 220). | 26678984 |
| Inflammation, Prostatic Infection | Altered Intercellular Communication | These findings suggest that, in addition to rising because of prostate infection, PSA may also rise because of systemic inflammation, which could have implications for PSA interpretation in older men. | 26678984 |
| Inflammation, Necrosis | Altered Intercellular Communication | A previous oral biopsy described fibrinoid necrosis, mixed inflammation, and granulation tissue. | 26679365 |
| Saint Lucia | Altered Intercellular Communication | CC seems to be a more severe type of bowel inflammation and LC tends to occur earlier in life. | 26679722 |
| Architectural Distortion, Inflammation, Colitis | Altered Intercellular Communication | Histologic examination showed patchy chronic colitis with crypt architectural distortion and mild-moderate inflammation activity. | 26680092 |
| Inflammation, Primary malignant neoplasm, Malnutrition | Altered Intercellular Communication | Preoperative albumin-globulin ratio (AGR) reflects both malnutrition and systemic inflammation in cancer patients. | 26681341 |
| Inflammation, Neoplasms, Malignant Neoplasms | Altered Intercellular Communication | In particular, systemic inflammation has been reported to contribute to tumor progression and poor oncological outcome in various malignancies. | 26681341 |
| ARCN1 gene, Airway structure, Chronic Obstructive Airway Disease, Obstruction, Asthma | Altered Intercellular Communication | Chronic obstructive pulmonary disease (COPD) and asthma are both characterized by heterogeneous chronic airway inflammation and obstruction as well as oxidative stress (OS). | 26681451 |
| Barrett Esophagus, Esophagitis, Adenocarcinoma | Altered Intercellular Communication | Epidemiologic data regarding coffee and tea consumption and risk of esophageal inflammation, Barrett's esophagus (BE), and adenocarcinoma are sparse and inconclusive. | 26681488 |
| Inflammation, Chronic heart failure, Venous Engorgement, Congestive heart failure | Altered Intercellular Communication | The goal of this study was to measure the presence of pathogenic gut flora and intestinal permeability (IP) and their correlations with disease severity, venous blood congestion, and inflammation in patients with chronic heart failure (CHF). | 26682791 |
| Inflammation, Blood Circulation | Altered Intercellular Communication | Evidence suggests that translocation of gut flora and/or their toxins from the intestine to the bloodstream is a possible trigger of systemic CHF inflammation. | 26682791 |
| Inflammation, Venous Engorgement, Congestive heart failure | Altered Intercellular Communication | However, the relation between pathogenic gut flora and CHF severity, as well as IP, venous blood congestion as right atrial pressure (RAP), and/or systemic inflammation (C-reactive protein [CRP]), is still unknown. | 26682791 |
| Inflammation, Congestive heart failure, Yersinia , Campylobacter, Candida (fungus) | Altered Intercellular Communication | Compared with normal control subjects, the entire CHF population had massive quantities of pathogenic bacteria and Candida such as Campylobacter (85.3 +- 3.7 CFU/ml vs. 1.0 +- 0.3 CFU/ml; p < 0.001), Shigella (38.9 +- 12.3 CFU/ml vs. 1.6 +- 0.2 CFU/ml; p < 0.001), Salmonella (31.3 +- 9.1 CFU/ml vs 0 CFU/ml; p < 0.001), Yersinia enterocolitica (22.9 +- 6.3 CFU/ml vs. 0 CFU/ml; p < 0.0001), and Candida species (21.3 +- 1.6 CFU/ml vs. 0.8 +- 0.4 CFU/ml; p < 0.001); altered IP (10.2 +- 1.2 mg vs. 1.5 +- 0.8 mg; p < 0.001); and increased RAP (12.6 +- 0.6 mm Hg) and inflammation (12.5 +- 0.6 mg/dl). | 26682791 |
| Inflammation, Venous Engorgement, Congestive heart failure, Overgrowth, Candida (fungus) | Altered Intercellular Communication | This study showed that patients with CHF may have intestinal overgrowth of pathogenic bacteria and Candida species and increased IP associated with clinical disease severity, venous blood congestion, and inflammation. | 26682791 |
| Inflammation, Heart failure, Left ventricular diastolic dysfunction, Hypertrophy | Altered Intercellular Communication | The present study investigated whether systemic, low-grade inflammation of metabolic risk contributed to diastolic left ventricular (LV) dysfunction and heart failure with preseved ejection fraction (HFpEF) through coronary microvascular endothelial activation, which alters paracrine signalling to cardiomyocytes and predisposes them to hypertrophy and high diastolic stiffness. | 26682792 |
| Astrocytoma, Inflammation | Altered Intercellular Communication | Several microRNAs found to be up-regulated in pilocytic astrocytomas are predicted to target the ERK/MAPK and NF-kB signaling pathways as well as genes involved in senescence-associated inflammation and cell cycle control. | 26682910 |
| Inflammation, Signs and Symptoms, Respiratory, Failure (biologic function) | Altered Intercellular Communication | Reasons for failure to meet the diagnostic criteria in 75 cases were lack of radiographic evidence in 60/75; lack of evidence of inflammation in 42/75, and lack of respiratory signs or symptoms in 13/75; 35/75 (47%) of cases lacked evidence in two or more domains. | 26683049 |
| Inflammation, Periodontitis | Altered Intercellular Communication | The up-regulated genes in periodontitis were related to inflammation, wounding and defense response, and apoptosis, whereas down-regulated genes were related to extracellular matrix organization and structural support. | 26686060 |
| Periodontitis, Ulcerative Colitis, Cardiovascular Diseases, Refractory anemias, Cyclophosphamide/Vincristine/Dacarbazine Regimen, Rheumatoid Arthritis | Altered Intercellular Communication | Here, we analyzed the global transcriptome of periodontitis and compared its gene expression profile with those of other inflammatory conditions, including cardiovascular disease (CVD), rheumatoid arthritis (RA), and ulcerative colitis (UC). | 26686060 |
| Osteoporosis | Altered Intercellular Communication | Osteoporosis is a chronic inflammatory condition that is characterized by the loss of bone mineral density (BMD). | 26686359 |
| Gout, Inflammatory, Rheumatoid Arthritis, Hereditary Diseases, Diabetes Mellitus, Non-Insulin-Dependent | Altered Intercellular Communication | Interleukin-1b (IL-1b) is a key cytokine involved in inflammatory illnesses including rare hereditary diseases and common chronic inflammatory conditions as gout, rheumatoid arthritis, and type 2 diabetes mellitus, suggesting reduction of IL-1b activity as new treatment strategy. | 26686385 |
| Inflammation, Virus Diseases | Altered Intercellular Communication | Saffold virus was detected in the myocardium, lung tissue and blood of one child and was accompanied by histopathological inflammation in the heart and lungs, which was supportive of a viral infection. | 26687438 |
| Inflammation, Hypoxia | Altered Intercellular Communication | Comparable correlations were exhibited in the ex-vivo explant tissue between metabolism, p53, hypoxia, inflammation and angiogenesis (P < 0.05). | 26688097 |
| Inflammation, Decline in functional status, Renal mass | Altered Intercellular Communication | To investigate association of C-reactive protein (CRP), a marker of systemic inflammation, with renal functional decline patients undergoing partial nephrectomy (PN) for renal mass. | 26688138 |
| ARCN1 gene, Inflammation, Atherosclerosis | Altered Intercellular Communication | At the same time STEMI and COPD patients demonstrated higher CRP levels, which reflected the activity of inflammation--one of mechanisms of atherosclerosis development. | 26688922 |
| Inflammation, Biliary Fistula | Altered Intercellular Communication | The impacted stones and surrounding inflammation can lead to a biliobiliary fistula. | 26688996 |
| Inflammation, Squamous cell carcinoma of esophagus | Altered Intercellular Communication | Prognostic nomogram integrated systemic inflammation score for patients with esophageal squamous cell carcinoma undergoing radical esophagectomy. | 26689680 |
| Inflammation, Neoplasms | Altered Intercellular Communication | Growing evidence indicates that nomogram combined with the biomarkers of systemic inflammation response could provide more accurate prediction than conventional staging systems in tumors. | 26689680 |
| Inflammation, Spondylarthritis | Altered Intercellular Communication | At present, there are no studies that have established a microRNA (miRNA)-based signature profile in patients with radiographic axial spondyloarthritis (rad-axial SpA), and we hypothesized that these patients may have aberrantly expressed circulating miRNAs reflective of underlying disease and inflammation. | 26689798 |
| Inflammation, Cardiovascular Diseases | Altered Intercellular Communication | Ageing, inflammation, and oxidative stress: final common pathways of cardiovascular disease. | 26690751 |
| Inflammation, Preterm premature rupture of membranes (disorder), Rupture | Altered Intercellular Communication | In women with preterm premature rupture of the membranes (PPROM), increased oxidative stress may accelerate premature cellular senescence, senescence-associated inflammation and proteolysis, which may predispose them to rupture. | 26690900 |
| Communicable Diseases, Hepatic inflammation | Altered Intercellular Communication | Future research should focus on interventions to promote abstinence and on treatments that suppress the hepatic inflammation without increasing susceptibility to infection. | 26691209 |
| Inflammation, Hypercholesterolemia, Thrombus | Altered Intercellular Communication | We conclude that smoking exacerbated the chronic inflammation induced by hypercholesterolemia, causing changes in his erythrocyte morphology and platelet activation, and suggest that ultrastructure here explains the clinical manifestations of the thrombotic state of this patient. | 26691215 |
| Drug-induced uveitis, Inflammatory abnormality of the eye | Altered Intercellular Communication | Drug-induced uveitis is a well-known effect of ocular inflammation that has been reported with many medications. | 26692064 |
| Inflammatory abnormality of the eye, Uveitis | Altered Intercellular Communication | Ophthalmologists should keep in mind that drugs are always a possible cause of ocular inflammation in patients presenting with uveitis. | 26692064 |
| Gingivitis, Dental Plaque | Altered Intercellular Communication | The use of each of the three tested toothpastes caused a significant reduction in gingival inflammation and amount of plaque. | 26694786 |
| Inflammation, Cardiovascular Diseases | Altered Intercellular Communication | Both are associated with inflammation, which may be partially triggered by oxidative stress, especially in cardiovascular disease. | 26695510 |
| Fatty Liver | Altered Intercellular Communication | Oxidative reactions are thought to play a role in the inflammatory condition called fatty liver. | 26695550 |
| Vasculitis | Altered Intercellular Communication | Orbital incisional biopsy suggested necrotising small vessel inflammation. | 26695609 |
| Inflammation, Gastritis, Chronic gastritis, Atrophic | Altered Intercellular Communication | Appropriate biopsy sampling is important for the classification of gastritis, yet the extent of inflammation and atrophy of different regions of the stomach with chronic gastritis have been addressed only in a few studies. | 26697568 |
| Inflammation, Ulcerative Colitis, Crohn Disease | Altered Intercellular Communication | Non-Invasive Assessment of Inflammation and Treatment Response in Patients with Crohn's Disease and Ulcerative Colitis using Contrast-Enhanced Ultrasonography Quantification. | 26697572 |
| Crohn Disease, Inflammation, Ulcerative Colitis | Altered Intercellular Communication | Novel biological therapies in Crohn's disease (CD) or Ulcerative colitis (UC) require a proper follow-up for the assessment of bowel inflammation. | 26697572 |
| Inflammation, physiopathological, Obesity | Altered Intercellular Communication | Recent work has found that older adults with obesity and systemic inflammation have associated metabolic dysfunction but do not have associated lower lean mass or strength. | 26698153 |
| Inflammation, Fever, CTCAE | Altered Intercellular Communication | Pathological findings showed only non-specific inflammation ; however, fever persisted postoperatively and blood test results showed no improvement. | 26699892 |
| orbit (eye disorders), Orbital Pseudotumor | Altered Intercellular Communication | IgG4-related orbital disease is a recognised cause for orbital inflammation. | 26700191 |
| Inflammation, Heart failure | Altered Intercellular Communication | Heart failure (HF) is associated with inflammation characterized by the formation of the inflammasome, which triggers maturation of inflammatory cytokines. | 26700661 |
| Inflammation, Rheumatoid Factor, immunoglobulin A | Altered Intercellular Communication | A significant decrease in IgG, IgA, IgM (p < 0.001 each), anticardiolipin antibodies IgG and IgM (p = 0.02), and beta-2 microglobulin (p = 0.004) was observed post-LT. HCV patients had higher IgG (p = 0.005), rheumatoid factor (p = 0.044) before LT; elevated IgM was associated with increased inflammation in the explant (p = 0.007). | 26700965 |
| Inflammation | Altered Intercellular Communication | Some immunological markers are associated with HCV recurrence and advanced inflammation on explant. | 26700965 |
| Inflammation, Muscle of orbit | Altered Intercellular Communication | Risk factors for an incomplete treatment response were male sex (P = .01) and inflammation extending to extraocular muscle (P = .01). | 26701269 |
| Inflammation | Altered Intercellular Communication | However, it may compromise aesthetics and contribute to gingival inflammation. | 26701991 |
| Inflammation | Altered Intercellular Communication | Given that B7-H3 expression on human monocytes and dendritic cells is enhanced by inflammatory cytokines, its potential inmmunoregulatory role at sites of inflammation has been suggested. | 26702052 |
| Airway structure, Virus Diseases, Herpes Simplex Infections | Altered Intercellular Communication | Th2 biased upper airway inflammation is associated with an impaired response to viral infection with Herpes simplex virus 1. | 26702454 |
| Inflammation, Acute infectious disease | Altered Intercellular Communication | We demonstrate for the first time in a human ex-vivo mucosal model that the inadequate response of CRSwNP may be associated with a deeper intrusion of viruses into the mucosal tissue, and may contribute to more and longer symptoms upon acute infection, but also to the persistence of inflammation in CRSwNP tissue. | 26702454 |
| Inflammation | Altered Intercellular Communication | This implies that mtDNA content might be a potential biomarker associated with oxidative stress and inflammation. | 26702630 |
| Acute inflammation | Altered Intercellular Communication | The topical NSAIDs ketorolac 0.4%, bromfenac 0.09%, and nepafenac 0.1% were effective for the reduction of postoperative inflammation following phacoemulsification. | 26703278 |
| Cataract, Pain Distress Question, Inflammatory abnormality of the eye | Altered Intercellular Communication | Sustained-release dexamethasone for the treatment of ocular inflammation and pain after cataract surgery. | 26703279 |
| Cataract, Inflammation, Pain Distress Question | Altered Intercellular Communication | Sustained-release dexamethasone provided elution of drug for up to 1 month after cataract surgery, providing clinically significant reductions in inflammation and pain. | 26703279 |
| Intraocular inflammation, Corneal edema, Edema | Altered Intercellular Communication | Postoperative CDVA, IOP, corneal edema, persistent intraocular inflammation, macular edema, and need for additional surgery were analyzed for the first postoperative year. | 26703285 |
| Inflammation, Cyclophosphamide/Vincristine/Dacarbazine Regimen, Cardiovascular Diseases | Altered Intercellular Communication | Inflammation has shown to be an independent predictor of cardiovascular disease (CVD) and growing evidence suggests Non-Hispanic Blacks (NHBs) and certain Hispanic subgroups have higher inflammation burden compared to Non-Hispanic Whites (NHWs). | 26703686 |
| Inflammation, Psoriasis | Altered Intercellular Communication | Psoriasis has been shown to accompany systemic inflammation. | 26704718 |
| Psoriatic Juvenile Idiopathic Arthritis, Inflammation | Altered Intercellular Communication | In conclusion, serum CRP levels can be used to assess disease severity in Japanese psoriatic patients as a marker of systemic inflammation. | 26704718 |
| Communicable Diseases, Inflammation | Altered Intercellular Communication | It is potentially a better biomarker to follow post-operative inflammation or early infection after TKA. | 26704797 |
| Inflammation | Altered Intercellular Communication | Functional studies are warranted to understand how specific monocyte subsets and systemic inflammation may contribute to ADHF pathophysiology. | 26705751 |
| Inflammation, Disability or Permanent Damage, Ischemic stroke | Altered Intercellular Communication | Acute ischemic stroke, the most frequent cause of permanent disability in adults worldwide, results from transient or permanent reduction in regional cerebral blood flow and involves oxidative stress and inflammation. | 26706245 |
| Inflammation, Hypertension, CTCAE, Serum LDL cholesterol measurement, Obesity | Altered Intercellular Communication | In multivariate regression including male gender, hypertension, smoking status, HOMA score, obesity, LDL-cholesterol, lipoprotein (a) or markers of inflammation, serum PCSK9 remained an independent predictor of mean carotid IMT (P<0.001). | 26706651 |
| Conjunctivitis | Altered Intercellular Communication | The conjunctival inflammation was mild in most of the cases at postoperative day 4. | 26706777 |
| Pain Distress Question, Fibromyalgia | Altered Intercellular Communication | These findings provide further support for a disruption of dopaminergic neurotransmission in FMS and implicate DA as important neurochemical moderator of differences in pain perception in FMS patients with and without co-morbid depression. | 26708319 |
| Intraocular inflammation, Uveitis | Altered Intercellular Communication | Anterior uveitis is the most common type of intraocular inflammation. | 26708737 |
| Multiple Myeloma, PMF Regimen | Altered Intercellular Communication | The expression of fibrosis-, inflammation-, and angiogenesis-associated genes was analyzed in a total of 52 bone marrow biopsies: PMF patients (n = 14) before and after ASCT and, for control purposes, post-ASCT multiple myeloma patients (n = 14) and non-neoplastic hematopoiesis (n = 10). | 26708839 |
| Inflammation, Hypertrophy | Altered Intercellular Communication | Inflammation is associated with prostatic enlargement and resistance to 5a-reductase inhibitor (5ARI) therapy. | 26709083 |
| Inflammation, Prostate carcinoma | Altered Intercellular Communication | Activation of the nuclear factor-kappa B (NF-kB) pathway is linked to both inflammation and ligand-independent prostate cancer progression. | 26709083 |
| Waldenstrom Macroglobulinemia, Immunoglobulin G4-Related Disease | Altered Intercellular Communication | IgG4 disease has been characterised by lymphoplasmacytic inflammation, rich in IgG4 plasma cells, elevated serum IgG4 and clinical improvement with steroid therapy. | 26710480 |
| Refractory anemias, Rheumatoid Arthritis, Inflammation | Altered Intercellular Communication | Rheumatoid arthritis (RA) may influence not only abdominal fat, but also whole body adiposity, since it is associated with chronic inflammation and disability. | 26710499 |
| Coronary artery ectasia, Inflammation | Altered Intercellular Communication | Gamma glutamyltransferase, inflammation and cardiovascular risk factors in isolated coronary artery ectasia. | 26711537 |
| Pain Distress Question, Inflammation, Intervertebral Disc Degeneration | Altered Intercellular Communication | Our current study strongly supports the potential of thalidomide for the treatment of pain and inflammation in degenerative disc disease. | 26711561 |
| Parkinson Disease, Inflammation, palladium | Altered Intercellular Communication | Parkinson's disease (PD) is characterised by low-level systemic inflammation, which may be at least partly due to pathophysiological activation of immunity. | 26711571 |
| Inflammation | Altered Intercellular Communication | A high proportion of older people is infected with cytomegalovirus (CMV), which acts as a chronic antigenic stressor that could also contribute to increased inflammation. | 26711571 |
| Inflammation, Lesion of retina | Altered Intercellular Communication | Ophthalmic examination a month and a half later showed almost all retinal lesions had disappeared and inflammation markers had returned to normal. | 26711674 |
| Breast Carcinoma | Altered Intercellular Communication | Systemic Correlates of White Adipose Tissue Inflammation in Early-Stage Breast Cancer. | 26712688 |
| Mastitis | Altered Intercellular Communication | In cohorts 1 and 2, breast WAT inflammation was detected in 52 of 100 (52%) and 52 of 127 (41%) patients, respectively. | 26712688 |
| Mastitis, Hyperlipidemia, Hypertension, CTCAE, Diabetes Mellitus | Altered Intercellular Communication | In cohort 2, breast WAT inflammation was associated with hyperlipidemia, hypertension, and diabetes (P < 0.05). | 26712688 |
| Mastitis, Inflammation | Altered Intercellular Communication | Compared with patients without breast WAT inflammation, the adjusted HR for dRFS was 1.83 (95% CI, 1.07-3.13) for patients with inflammation. | 26712688 |
| Inflammation, Breast Carcinoma, Metabolic Syndrome X | Altered Intercellular Communication | WAT inflammation, a clinically occult process, helps to explain the relationship between metabolic syndrome and worse breast cancer prognosis. | 26712688 |
| Colorectal Carcinoma | Altered Intercellular Communication | Prognostic Inflammation Score in Surgical Patients with Colorectal Cancer. | 26713054 |
| Inflammation, HIV Infections | Altered Intercellular Communication | Recent studies suggest that increased immune activation and inflammation may contribute to excess risk for CVD in the context of HIV infection. | 26713505 |
| Inflammation, Demographics Domain, Degenerative polyarthritis, Obesity, Diabetes Mellitus, Non-Insulin-Dependent | Altered Intercellular Communication | Obesity is a state of chronic inflammation that is associated with insulin resistance and type 2 diabetes mellitus (DM), as well as an increased risk of osteoarthritis (OA). | 26713606 |
| Degenerative polyarthritis, Inflammation, Tumor necrosis | Altered Intercellular Communication | This study was undertaken to define the links between obesity-associated inflammation, insulin resistance, and OA, by testing the hypotheses that 1) tumor necrosis factor (TNF) is critical in mediating these pathologic changes in OA, and 2) insulin has direct effects on the synovial joint that are compromised by insulin resistance. | 26713606 |
| Inflammation, Endotoxemia, diabetic | Altered Intercellular Communication | Our data indicate that diabetic HD-patients are particularly prone to splanchnic ischemia and might therefore have an increased risk for bacterial translocation, endotoxemia and systemic inflammation. | 26713734 |
| Degenerative polyarthritis, Inflammation, Hypertension, CTCAE, Obesity | Altered Intercellular Communication | Participants with OA had more potential CVD risk factors, including obesity, hypertension, high levels of low-density lipoprotein, greater severity of inflammation, and worse renal function, than did those without OA. | 26714002 |
| Airway structure, Asthma | Altered Intercellular Communication | We sought to compare coagulation and fibrinolysis parameters between healthy subjects and patients with mild, severe, and prednisolone-dependent asthma under stable conditions and to investigate whether hemostatic markers correlate with airway inflammation. | 26714414 |
| Weight Gain, Inflammation, Coronary Artery Disease | Altered Intercellular Communication | Association of weight gain with coronary artery disease, inflammation and thrombogenicity. | 26714821 |
| Weight Gain, Inflammation, Coronary Artery Disease | Altered Intercellular Communication | Little is known about association of long-term weight gain to development of coronary artery disease (CAD), inflammation and thrombogenicity. | 26714821 |
| Weight Gain, Inflammation | Altered Intercellular Communication | Our data suggest that maximal weight gain since age 17 years is associated with heightened thrombogenicity, inflammation and a poorer lipid profile but not an increased risk for severe CAD development. | 26714821 |
| Necrotizing granulomatous inflammation, Lesion of breast | Altered Intercellular Communication | Histologic examination of the palatal and breast lesions showed chronic granulomatous inflammation. | 26714880 |
| Inflammation, Neoplasms | Altered Intercellular Communication | Moreover, supernatant from tumor B cells suppressed T cell inflammation. | 26715281 |
| Inflammation, Disease | Altered Intercellular Communication | Although both diseases have been linked with systemic inflammation, studies on their potential bidirectional association are lacking. | 26715401 |
| Inflammation | Altered Intercellular Communication | This case report describes a 16-month-old boy of Hispanic/African American ethnicity who had extensive inflammation of and discharge from his right ankle. | 26715611 |
| Inflammation, Refractory anemias, Rheumatoid Arthritis, Inflammatory disorder, Disability | Altered Intercellular Communication | Rheumatoid arthritis (RA) is a chronic systemic inflammatory disease characterized by synovial inflammation and joint disability. | 26716989 |
| Refractory anemias, Inflammation | Altered Intercellular Communication | Curcumin is known to be effective in ameliorating joint inflammation in RA. | 26716989 |
| Shock, Inflammation, Damage, Septic Shock | Altered Intercellular Communication | Plasma Nuclear and Mitochondrial DNA Levels, and Markers of Inflammation, Shock, and Organ Damage in Patients with Septic Shock. | 26717107 |
| Shock, Inflammation, Damage, Septic Shock | Altered Intercellular Communication | Our aim was to determine whether plasma levels of nDNA and mtDNA are related to the markers of inflammation, severity of shock, and organ damage in septic shock patients. | 26717107 |
| Sepsis, Inflammation, Endotoxemia | Altered Intercellular Communication | Moreover, we investigated the relationship between plasma levels of nDNA/mtDNA and inflammatory cytokines during experimental human endotoxemia, a model of systemic inflammation in humans in vivo mimicking some of the hallmarks of early sepsis. | 26717107 |
| methyldopa, Inflammation, Limited stage (cancer stage) | Altered Intercellular Communication | Consistent with other evidence supporting the role of inflammation and the immune system in AMD pathogenesis, AAbs were identified in AMD sera, including early-stage disease. | 26717306 |
| Inflammation, Periodontitis, Chronic Kidney Diseases | Altered Intercellular Communication | Sources of chronic systemic inflammation (including periodontitis) may be important contributors to mortality in patients with CKD. | 26717883 |
| Autoimmune Diseases, Inflammation, Malignant Peripheral Nerve Sheath Tumor, Atherosclerosis | Altered Intercellular Communication | It is discussed if chronic inflammation in relation to autoimmunity and atherosclerosis might elicit mutations in the hematopoietic stem cell resulting in MPNs, or whether this association actually reflects a long-lasting pre-MPN-diagnosis phase, in which the MPN-disease per se contributes to a chronic inflammatory state and immune deregulation. | 26718091 |
| Communicable Diseases, Inflammation | Altered Intercellular Communication | Non-typeable Haemophilus influenzae (NTHi) is a human restricted commensal and pathogen that elicits inflammation by adhering to and invading airway epithelia cells: transcytosis across these cells can result in systemic infection. | 26718097 |
| Intraocular inflammation | Altered Intercellular Communication | In this case, its inert nature did not cause any further intraocular inflammation. | 26718222 |
| Inflammation, FBN1 gene, Disease remission, Granulomatosis, Subglottic stenosis, Systemic Vasculitis | Altered Intercellular Communication | Subglottic stenosis (SGS) in granulomatosis with polyangiitis (GPA) may result from active disease or from chronic recurrent inflammation. | 26718390 |
| Inflammation, Diabetic Retinopathy, GDC Disease Response Terminology | Altered Intercellular Communication | Inflammation plays an important role in the pathogenesis of diabetic retinopathy (DR). | 26718887 |
| Weight Gain, Inflammation | Altered Intercellular Communication | The findings suggest that weight gain in adulthood is associated with low-grade inflammation in late midlife. | 26718895 |
| Airway structure, ARCN1 gene, Inflammation | Altered Intercellular Communication | Because airway inflammation is a hallmark of COPD, it has been proposed that measuring exhaled nitric oxide, a marker of inflammation, in exhaled breath condensate could prove to be an inexpensive and efficient method to detect COPD in outpatient settings. | 26718918 |
| ARCN1 gene, Inflammation | Altered Intercellular Communication | The findings of this study do not support use of eNO as a biomarker of inflammation in diagnosis and management of COPD. | 26718918 |
| Refractory anemias, Inflammation | Altered Intercellular Communication | These findings emphasise the adverse effects of chronic inflammation on the durability of PCI and provide further support for aggressive anti-inflammatory treatment in patients with RA. | 26719360 |
| Inflammation | Altered Intercellular Communication | The ION-enlarged group showed a higher percentage of the patients with diffuse inflammation (66.7%, p<0.001). | 26719493 |
| Inflammation, Hypertrophy | Altered Intercellular Communication | Repetitive inflammation (recurrence >=3) with steroid dependency was found only in 19.5% patients without ION enlargement but in 66.7% patients with ION enlargement. | 26719493 |
| Inflammation | Altered Intercellular Communication | Further insights in understanding their role in corneal wound inflammation may help design new therapeutic strategies. | 26720440 |
| Inflammation, Postoperative Hemorrhage | Altered Intercellular Communication | In conclusion, postoperative bleeding is reduced in patients who continued aspirin, likely due to a reduction in postoperative inflammation. | 26721653 |
| Ruptured behavior, Inflammation, Cholesteatoma | Altered Intercellular Communication | We sought to investigate if second-look procedures after endoscopic-assisted surgery could safely be performed only in children at a high risk of residual disease (extensive inflammation, spontaneously ruptured or fragmented cholesteatoma, residual disease intentionally left). | 26721891 |
| Inflammatory Bowel Diseases, Inflammation, Abdominal Pain | Altered Intercellular Communication | In a post hoc analysis of pooled data from two randomized controlled trials we assessed the association between demographic data (gender, age, smoking habits, family history of inflammatory bowel disease), clinical variables (duration of symptoms, mean number of stools/watery stools per day, abdominal pain, clinical remission) and histological data (thickness of the collagen band, inflammation of the lamina propria, total numbers of intraepithelial lymphocytes, degeneration). | 26721941 |
| Inflammation, Mood Disorders | Altered Intercellular Communication | The role of inflammation in mood disorders has received increased attention. | 26721949 |
| Depression, CTCAE | Altered Intercellular Communication | Glucocorticoid Receptors, Brain-Derived Neurotrophic Factor, Serotonin and Dopamine Neurotransmission are Associated with Interferon-Induced Depression. | 26721949 |
| Kidney Failure, Chronic, Inflammation | Altered Intercellular Communication | Patients with end stage renal failure (ESRD) report low quality of life and inflammation may be one of the contributing factors. | 26722560 |
| Inflammation, Metabolic Diseases | Altered Intercellular Communication | Further adjustment for metabolic disease slightly reduced the associations while adjustment for inflammation markedly reduced the associations. | 26724528 |
| Inflammation, Metabolic Diseases | Altered Intercellular Communication | In older adults, higher resistin levels are associated with CVD events independently of clinical risk factors and metabolic disease markers, but markedly attenuated by inflammation. | 26724528 |
| Inflammation, Calcinosis | Altered Intercellular Communication | These alterations correlated with oxidative stress, inflammation, senescence and calcification (all p < 0.05). | 26724531 |
| Inflammation, Calcinosis | Altered Intercellular Communication | ZMPSTE24 silencing in native VSMCs recapitulated the mutant LMNA- and PI-induced accumulation of farnesylated prelamin A, oxidative stress, inflammation, senescence and calcification. | 26724531 |
| Inflammation | Altered Intercellular Communication | In multivariate analysis, parameters that affected gastric emptying T 1/2 time were found as serum gastrin level (OR 1.002, 95 % CI 1.001-1.004, p < 0.001, chronic inflammation (OR 3.689, 95 % CI 1.44-9.39, p < 0.001), and increase in the degree of the atrophy of the gastric mucosa (OR 8.96, 95 % CI 2.98-26.93, p < 0.001). | 26725066 |
| Craniocerebral Trauma, Inflammation | Altered Intercellular Communication | However in animal models brain inflammation, which can be initiated by head trauma, has been shown to produce PD-like effects. | 26725141 |
| palladium, Inflammation | Altered Intercellular Communication | Furthermore, animal studies have found that early life inflammation in particular is of relevance for PD pathology. | 26725141 |
| Inflammation, Pulpitis | Altered Intercellular Communication | Differentiation between reversible pulpitis (savable pulp) and irreversible inflammation of the pulp tissue (nonsavable pulp) based only on clinical and radiographic diagnoses has proven to be difficult. | 26725178 |
| Inflammation, Depression, CTCAE, HIV Infections | Altered Intercellular Communication | These findings suggest that SSRI treatment, independent of depression status, downregulates HIV receptor and coreceptor expression and may reduce susceptibility of immune cells to HIV infection and decrease inflammation. | 26725193 |
| Inflammation, Impaired cognition, Cerebral Small Vessel Diseases, Atherosclerosis | Altered Intercellular Communication | Inflammation is implicated in atherosclerosis, cerebral small-vessel disease (SVD) as well as cognitive impairment. | 26725994 |
| Renal Insufficiency, Reperfusion Injury, Kidney Failure, Acute, Nephritis | Altered Intercellular Communication | When subjected to ischemia-reperfusion (IR)-induced AKI, AIM-deficient mice exhibited abrogated debris clearance and persistent renal inflammation, resulting in higher mortality than wild-type (WT) mice due to progressive renal dysfunction. | 26726878 |
| Sepsis, Inflammation, Traumatic injury | Altered Intercellular Communication | In severe trauma, overwhelming systemic inflammation can result in additional damage and the development of complications, including sepsis. | 26727089 |
| Sepsis, Inflammation | Altered Intercellular Communication | Transcriptome profiling of the discovery set revealed the strongest changes between patients with either systemic inflammation or sepsis in gene expression of the heme degradation pathway. | 26727089 |
| Sepsis, Inflammation | Altered Intercellular Communication | Upregulation of HP was associated with the severity of systemic inflammation and the development of sepsis. | 26727089 |
| palladium, Inflammation | Altered Intercellular Communication | Serum and drained dialysate concentrations of VEGF in PD patients were connected with poorer metabolic profile, while the role of inflammation and treatment agents should be studied further. | 26727866 |
| Chronic Kidney Diseases | Altered Intercellular Communication | Intact FGF23 and a-Klotho during acute inflammation/sepsis in CKD patients. | 26728476 |
| Inflammation, Chronic Kidney Diseases | Altered Intercellular Communication | High FGF23 and low a-Klotho levels associate with systemic inflammation and reduced nitric oxide (NO) bioavailability, but the dynamics of this relationship in patients with CKD has not been investigated. | 26728476 |
| Sepsis, Inflammation, Chronic kidney disease mineral and bone disorder, Chronic Kidney Diseases | Altered Intercellular Communication | We sequentially measured serum intact FGF23 and carboxyl-terminal (iFGF23, cFGF23), the iFGF23/cFGF23 ratio, aKlotho, biomarkers of inflammation (hs-CRP, IL-6 and TNF-a) and sepsis (procalcitonin), nitrotyrosine (reflecting NO synthesis and oxidative stress), serum iron and ferritin and CKD-MBD biomarkers, PTH, 25(OH)VD, 1,25(OH)2 VD at peak of intercurrent sepsis and after complete resolution in a series of 17 patients with CKD. | 26728476 |
| Communicable Diseases | Altered Intercellular Communication | At peak infection, biomarkers of inflammation/sepsis, ferritin and nitrotyrosine were all very high (all P < 0*01) and declined towards the normal range thereafter (P < 0*01). | 26728476 |
| Sepsis, Inflammation, Chronic Kidney Diseases | Altered Intercellular Communication | iFGF23 downregulation and a-Klotho upregulation during acute sepsis may participate into the counter-regulatory response to severe inflammation in CKD patients with sepsis. | 26728476 |
| Fibrosis Assessment, Interstitial inflammation | Altered Intercellular Communication | This was associated with less renal cortical fibrosis and interstitial inflammation compared to nontransplanted mice as shown by reduction in murine CD4, CD68, and CD45.2 cells. | 26728561 |
| Inflammation, Fibrosis Assessment | Altered Intercellular Communication | The cardiovascular magnetic resonance study (CMR) included evaluation of function, inflammation and fibrosis. | 26728774 |
| Inflammation, Metabolic Syndrome X, MS gene | Altered Intercellular Communication | Inflammation plays an important role in the pathogenesis of metabolic syndrome (MS). | 26728949 |
| Inflammation, FAM126A gene | Altered Intercellular Communication | Recently, neutrophil-to-lymphocyte ratio (NLR), a marker of systemic inflammation that is associated with tumor-associated macrophages (TAMs), was suggested to be a prognostic marker of HCC treated with RFA. | 26729319 |
| Inflammation, Mycobacterium Infections | Altered Intercellular Communication | Histology of his pleural biopsy identified multiple non-confluent necrotising granulomatous inflammation with very occasional acid-alcohol-fast bacilli-like organisms, highly suspicious for mycobacterial infection. | 26729824 |
| ARCN1 gene, Eosinophilic inflammation | Altered Intercellular Communication | COPD patients with increased airway eosinophilic inflammation show a favorable response to inhaled corticosteroids (ICS) in combination with a long-acting bronchodilator. | 26730185 |
| ARCN1 gene | Altered Intercellular Communication | Cigarette smoke-induced lung inflammation in COPD mediated via LTB4/BLT1/SOCS1 pathway. | 26730186 |
| Inflammation, Pulmonary Emphysema | Altered Intercellular Communication | Long-term cigarette smoke exposure induced SOCS1 degradation and LTB4 accumulation, which was associated with emphysema and inflammation. | 26730186 |
| Intraocular inflammation | Altered Intercellular Communication | No evidence of additional intraocular inflammation was present. | 26731215 |
| Fibrosis Assessment, Hepatitis, Chronic, Splenomegaly | Altered Intercellular Communication | Schistosoma eggs cause chronic liver inflammation and a complex disease characterized by hepatic fibrosis (HF) and splenomegaly (SplM). | 26731721 |
| Schistosomiasis, Inflammation | Altered Intercellular Communication | FOXP3+ Tregs could regulate inflammation, but it is unclear where these cells are produced and what roles they play in human schistosomiasis. | 26731721 |
| Schistosomiasis, Inflammation | Altered Intercellular Communication | In most cases, Tregs migrate to the Th1-infiltrated liver and the lower levels of CXCR3+ Tregs in the blood of patients with severe schistosomiasis suggest that decreases in Treg migration sites of inflammation may aggravate the disease. | 26731721 |
| Inflammation, Endothelial dysfunction | Altered Intercellular Communication | Fine particles, genetic pathways, and markers of inflammation and endothelial dysfunction: Analysis on particulate species and sources. | 26732377 |
| Inflammation, Endothelial dysfunction | Altered Intercellular Communication | Our findings suggest that particles derived from oil combustion may be associated with inflammation and endothelial dysfunction, and it is likely that oxidative stress plays a role in the associations. | 26732377 |
| methyldopa, Inflammation | Altered Intercellular Communication | Age-related macular degeneration (AMD) risk variants in the complement system point to the important role of immune response and inflammation in the pathogenesis of AMD. | 26733291 |
| Inflammation, Diabetes Mellitus | Altered Intercellular Communication | Adiponectin, markers of subclinical inflammation and nerve conduction in individuals with recently diagnosed type 1 and type 2 diabetes. | 26733478 |
| Endothelial dysfunction | Altered Intercellular Communication | These findings suggest that positive and negative psychological factors affect DNA methylation of selected genes involved in chronic immune/inflammatory processes and inflammation-related endothelial dysfunction. | 26733571 |
| Vaginitis | Altered Intercellular Communication | The cause of the adhesion was considered to be vaginal inflammation induced by anticancer agents themselves. | 26735150 |
| Inflammation, Cerebral dysfunction | Altered Intercellular Communication | Systemic inflammation on postnatal days 21 and 28 and indicators of brain dysfunction 2years later among children born before the 28th week of gestation. | 26735345 |
| Inflammation, Mental disorders | Altered Intercellular Communication | Systemic inflammation during the first two postnatal weeks in extremely preterm newborns (<28weeks gestation) has been associated with an increased risk of neurodevelopmental dysfunctions. | 26735345 |
| Inflammation | Altered Intercellular Communication | Little is known, however, about the relationship between systemic inflammation during the third and fourth postnatal weeks and subsequent development. | 26735345 |
| Inflammation, Cerebral ventriculomegaly, Microcephaly | Altered Intercellular Communication | Top quartile concentrations of CRP, SAA, IL-6, TNF-R2, IL-8, and ICAM-1 were associated with mental development index (MDI) of the Bayley-II<55, while top quartile concentrations of CRP, TNF-a (inversely), IL-8, and ICAM-1 were associated with psychomotor development index (PDI)<55 CONCLUSION: Extremely preterm newborns who had systemic inflammation during the third and fourth postnatal weeks were at increased risk of ventriculomegaly during the months after birth, and of microcephaly, and low Bayley Scale scores at 2years old. | 26735345 |
| Inflammation | Altered Intercellular Communication | A severe local inflammation with raised CRP levels, however, might affect accurate 18F-FDG quantification in CRC tumors. | 26735530 |
| Cessation of life, Inflammation | Altered Intercellular Communication | Pathway analysis demonstrated that these genes are involved in cell death, inflammation, cardiac remodeling and nervous system function. | 26735598 |
| Alzheimers Disease", Inflammation | Altered Intercellular Communication | Alzheimer disease, inflammation, and novel inflammatory marker: resistin. | 26738345 |
| Inflammation, "Alzheimers Disease", Data types - Address | Altered Intercellular Communication | Inflammation may play an important role in Alzheimer disease (AD) pathogenesis. | 26738345 |
| Inflammation | Altered Intercellular Communication | The fractional exhaled nitric oxide concentration (FENO) is used as a noninvasive biomarker for asthmatic inflammation. | 26738370 |
| nervous system disorder | Altered Intercellular Communication | This presynaptic high-voltage-gated channel couples neuronal excitation to the vesicular release of neurotransmitter and is implicated in several neurologic disorders. | 26739101 |
| Hepatitis, FAM126A gene | Altered Intercellular Communication | Our data suggest that CTGF could be involved in oncogenic pathways promoting non-viral HCC associated with metabolic risk factors via induction of liver inflammation and is expected to be a novel HCC risk biomarker and potential therapeutic target. | 26739296 |
| Inflammation, Lymphohistiocytosis, Hemophagocytic | Altered Intercellular Communication | Hemophagocytic lymphohistiocytosis (HLH) is a fatal clinical syndrome characterized by excessive immune activation and inflammation. | 26739581 |
| Inflammation, Malignant Neoplasms | Altered Intercellular Communication | As a surrogate marker of systemic inflammation, the lymphocyte-to-monocyte ratio (LMR) is an independent prognostic factor for various malignancies. | 26740116 |
| Inflammation, Encephalomyelitis, Acute Disseminated | Altered Intercellular Communication | Of 105,557 patients screened, 774 (0.7%) fulfilled entry criteria for CNS infection/inflammation, with 114 cases ascertained as ADEM. | 26741581 |
| Inflammation, Encephalomyelitis, Acute Disseminated | Altered Intercellular Communication | Parechoviruses were detected in 2.5% of patients with CNS infection/inflammation, including 1 case fulfilling ADEM case criteria with the highest level of diagnostic certainty. | 26741581 |
| Inflammation | Altered Intercellular Communication | Inflammation is an important reaction underlying lumbar disc herniation (LDH). | 26742440 |
| Autoimmune Diseases, Inflammation | Altered Intercellular Communication | It plays important roles in chronic inflammation and autoimmune diseases. | 26742440 |
| Inflammation, Pain Distress Question | Altered Intercellular Communication | Enhanced production of IL-21 in disc tissues of LDH patients was also confirmed using immunohistochemical analyses.We concluded that inflammation was responsible for the pain associated with LDH, and that increased IL-21 expression may be associated with the pathogenesis of LDH. | 26742440 |
| Inflammation, Hepatitis B | Altered Intercellular Communication | Pre-vaccination inflammation and B-cell signalling predict age-related hyporesponse to hepatitis B vaccination. | 26742691 |
| Inflammation, Fibrosis Assessment | Altered Intercellular Communication | Inflammation and fibrosis were analysed with histological criteria and SPK1 expression was determined by individual immunohistochemical staining. | 26742972 |
| Inflammatory abnormality of the eye | Altered Intercellular Communication | Despite the aggressive course of ocular inflammation, her visual acuity remained good. | 26743185 |
| Inflammation, Periodontal Diseases | Altered Intercellular Communication | Cyclooxygenase-2 and matrix metalloproteinase-9 expressions correlate with tissue inflammation degree in periodontal disease. | 26743292 |
| Gingivitis, Inflammation, Periodontitis, Periodontal Diseases, Chronic inflammatory disorder | Altered Intercellular Communication | The aim of our study was to correlate the intensity of inflammation with MMP-9 and Cox-2 expression in the periodontal tissue of patients with chronic inflammatory disease (gingivitis and chronic periodontitis) in order to determine the role of these two biomarkers in the progression of periodontal disease. | 26743292 |
| Inflammation | Altered Intercellular Communication | In these three groups, we graded the intensity of inflammation in the lamina propria and the immunohistochemical expression of MMP-9 and Cox-2. | 26743292 |
| Gingivitis, Inflammation, Periodontitis | Altered Intercellular Communication | The presence of a large number of inflammatory cells in the lamina propria in patients with gingivitis or chronic periodontitis (Groups II and III) correlated with the clinically diagnosed inflammation of the gingival tissue. | 26743292 |
| Gingivitis, Inflammation, Periodontitis | Altered Intercellular Communication | The expression of Cox-2 in periodontitis was also higher compared to gingivitis (p=0.05, Mann-Whitney U-test) and to controls (p=0.001, Mann-Whitney U-test).The inflammation score could be positively correlated to the MMP-9 and Cox-2 expression scores at the overall study group, but not separately on gingivitis and periodontitis patients. | 26743292 |
| Communicable Diseases, Inflammation | Altered Intercellular Communication | Infection or inflammation (a1-acid glycoprotein >1*2 g/l) was present in 30*2 % (n 184) of children. | 26743501 |
| Inflammation, Peritubular Capillaritis Assessment, Glomerulitis (disorder) | Altered Intercellular Communication | The key lesions in antibody-mediated kidney transplant rejection (ABMR) are microcirculation inflammation (peritubular capillaritis and/or glomerulitis lesions, abbreviated "pg") and glomerular double contours (cg lesions). | 26743766 |
| Inflammation, disc disorder | Altered Intercellular Communication | These findings suggest that LBP subjects have low-grade systemic inflammation, and biochemical profiling of circulating cytokines may assist in refining personalized diagnoses of disc diseases. | 26743937 |
| Autoimmune Diseases, Inflammation | Altered Intercellular Communication | Natural IgM antibodies (nIgM) are polyreactive autoantibodies that have diverse roles in regulating autoimmunity, systemic inflammation and removal of oxidized low-density lipoproteins (oxLDL). | 26744098 |
| Inflammation, Microalbuminuria, Cerebrovascular accident, Leukoencephalopathy, Chronic Kidney Diseases | Altered Intercellular Communication | The primary aim is to characterize the association between (1) baseline and incident stroke, white matter disease, estimated glomerular filtration rate (eGFR), inflammation, microalbuminuria, and dialysis initiation and (2) cognitive decline over 3 years in a CKD cohort with a mean eGFR<45 mL/min/1.73 m(2). | 26744128 |
| Inflammation, Endothelial dysfunction, Atherosclerosis | Altered Intercellular Communication | Baseline as well as cumulated values of markers reflecting systemic inflammation, lymphocyte activation, endothelial dysfunction and oxidative stress were not correlated with carotid subclinical atherosclerosis. | 26744355 |
| Amyotrophic Lateral Sclerosis, Inflammation, Pathology | Altered Intercellular Communication | In amyotrophic lateral sclerosis, we have shown that transplanted spinal neural stem cells (NSCs) integrate into the spinal cord, form synapses with the host, improve inflammation, and reduce disease-associated pathologies. | 26744412 |
| Thyroiditis | Altered Intercellular Communication | A correlation between globus pharyngeus and thyroid gland inflammation has been mentioned in previous studies. | 26744863 |
| Inflammation, Swelling, Contusions | Altered Intercellular Communication | Other injection site reactions included nodules (38%), swelling (28%), bruising (16%), scar tissue (8%) and inflammation (7%). | 26744896 |
| Inflammation, ETV3 wt Allele | Altered Intercellular Communication | Our results add to the evidence that chronic inflammation is a candidate mechanism at the crossroad between MetS and BPH/LUTS, and the presence of elevated MPV may serve as a predictor of MetS-induced inflammation in the progression of BPH/LUTS. | 26745140 |
| Inflammation | Altered Intercellular Communication | They are shed from nearly every activated or preapoptotic cell and may exhibit biologic activities in inflammation or apoptosis settings. | 26746017 |
| Inflammation, Arthritis | Altered Intercellular Communication | GPs mainly used classical signs of inflammation to diagnose inflammatory arthritis. | 26747844 |
| Inflammation | Altered Intercellular Communication | Background Endocan (endothelial cell-specific molecule-1) is a proteoglycan and plays an important role in angiogenesis and inflammation. | 26748103 |
| Gastroesophageal reflux disease, Inflammation, Autonomic neuropathy | Altered Intercellular Communication | The results are consistent with a growing body of evidence that cardiac autonomic neuropathy as measured by HRV is associated with gastro-esophageal reflux disease and also suggest that successful treatment of the inflammation can lead to reversal of the deterioration of autonomic tone associated with that inflammation. | 26748487 |
| Degenerative polyarthritis, Pain Distress Question, Inflammation | Altered Intercellular Communication | In patients with knee OA, serum hsCRP is associated with knee BML scores and, to a lesser extent, pain both cross-sectionally and longitudinally, suggesting that inflammation is linked with BMLs and their associated pain. | 26748954 |
| Inflammation, OED gene | Altered Intercellular Communication | Gene ontology enrichment revealed LAF in OEH was mostly due to changes in inflammation, cell cycle regulation and apoptosis, while in OED was due to inflammation, angiogenesis and extracellular matrix remodelling. | 26749103 |
| Inflammation, Coombs positive hemolytic anemia | Altered Intercellular Communication | The blood test shows Coombs-positive hemolytic anemia and inflammation. | 26749635 |
| ARCN1 gene, Chronic Obstructive Airway Disease, Pulmonary Emphysema, Airway structure | Altered Intercellular Communication | Chronic obstructive pulmonary disease (COPD) is a heterogeneous disease with small airway inflammation and emphysema. | 26749913 |
| Achondroplasia | Altered Intercellular Communication | Dwarfism may be due to achondroplasia or hormonal growth disorders. | 26750695 |
| Kidney Failure, Chronic, Inflammation, Chronic Kidney Diseases | Altered Intercellular Communication | To assess the contribution of TMAO to inflammation and mortality in chronic kidney disease (CKD) patients ranging from mild-moderate to end-stage disease and 1) associations with glomerular filtration rate (GFR) 2) effect of dialysis and renal transplantation (Rtx) 3) association with inflammatory biomarkers and 4) its predictive value for all-cause mortality. | 26751065 |
| Upper Respiratory Infections | Altered Intercellular Communication | Although respiratory reactions following ingestion of ASA and other nonsteroidal anti-inflammatory drugs (NSAIDs) are considered a hallmark of the condition, respiratory inflammation persists despite patients' avoidance of NSAIDs. | 26751262 |
| TNF protein, human, Tumor necrosis, Inflammation | Altered Intercellular Communication | The C-reactive protein (CRP) and the tumor necrosis factor-alpha (TNF-a) are considered markers of inflammation and have been shown to predict the risk of incident cardiovascular events. | 26751459 |
| Inflammation, Mean mid-expiratory flow rate, Anemia | Altered Intercellular Communication | MMFR combined with non-nutritional approaches addressing anemia and inflammation should be further investigated. | 26751473 |
| Pain in elbow | Altered Intercellular Communication | Humeral epicondylitis, a relatively common disease, is classified among inflammatory conditions of soft tissues and is frequently associated with elbow pain. | 26751747 |
| Autoimmune Diseases, Inflammation | Altered Intercellular Communication | Natural killer (NK) cells are swiftly mobilized to organs targeted by autoimmunity and typically undergo numerical contraction when inflammation wanes. | 26752157 |
| ARCN1 gene | Altered Intercellular Communication | The MIF Antagonist ISO-1 Attenuates Corticosteroid-Insensitive Inflammation and Airways Hyperresponsiveness in an Ozone-Induced Model of COPD. | 26752192 |
| ARCN1 gene, AHR wt Allele | Altered Intercellular Communication | MIF and HIF-1a levels are elevated in COPD BAL macrophages and inhibition of MIF function blocks corticosteroid-insensitive lung inflammation and AHR. | 26752192 |
| Inflammation, Centers for Disease Control and Prevention (U.S.) | Altered Intercellular Communication | Resolution of tendinoses reversed the inflammation causing the CDC. | 26752490 |
| Multiple Organ Failure, Inflammation, Pancreatitis, Organ dysfunction syndrome, Cessation of life | Altered Intercellular Communication | Acute pancreatitis (AP) is a common and devastating inflammatory condition of the pancreas that is considered to be a paradigm of sterile inflammation leading to systemic multiple organ dysfunction syndrome (MODS) and death. | 26752518 |
| Multiple Organ Failure, Inflammation, Pancreatitis, Organ dysfunction syndrome, Cessation of life | Altered Intercellular Communication | Acute pancreatitis (AP) is a common and devastating inflammatory condition of the pancreas that is considered to be a paradigm of sterile inflammation leading to systemic multiple organ dysfunction syndrome (MODS) and death. | 26752518 |
| ARCN1 gene, Lung Injury, Pneumonitis, Impaired | Altered Intercellular Communication | Mitochondrial iron chelation also alleviated CS-induced impairment of MCC, CS-induced pulmonary inflammation and CS-associated lung injury in mice with established COPD, suggesting a critical functional role and potential therapeutic intervention for the mitochondrial-iron axis in COPD. | 26752519 |
| Malignant Neoplasms | Altered Intercellular Communication | Modified inflammation-based score was identified as an independent predictor of malignancies in patients with pulmonary fGGOs. | 26752624 |
| Inflammation, Atherosclerosis | Altered Intercellular Communication | Inflammation plays a key role in the pathophysiology of atherosclerosis. | 26752692 |
| Multiple polyps, Rhinosinusitis, Airway structure, Asthma, Respiration Disorders | Altered Intercellular Communication | Aspirin-exacerbated respiratory disease (AERD), formerly known as Samter's Triad, is a syndrome of airway inflammation characterized by rhinosinusitis with polyposis, asthma, and nonsteroidal anti-inflammatory drug (NSAID) intolerance. | 26753248 |
| Pain Distress Question, Inflammation, Swelling, Lymphedema, Disability | Altered Intercellular Communication | Lymphedema, typically presents symptoms of swelling, pain, inflammation, and itching, and it can generate, over the years, acute disability in the affected limbs. | 26753640 |
| Photoreceptor degeneration, Inflammation | Altered Intercellular Communication | Here, we identify IL-33 as a key regulator of inflammation and photoreceptor degeneration after retina stress or injury. | 26755704 |
| Electrocardiogram: myocardial infarction (finding), Myocarditis | Altered Intercellular Communication | We report the case of a 62-year-old woman with a history of ST-elevation myocardial infarction who underwent 68Ga-Pentixafor PET/CT for characterization of postinfarct myocardial inflammation. | 26756098 |
| Inflammation, Fracture | Altered Intercellular Communication | The local enhanced activity was associated with the development of clinical complications such as chest wall inflammation and rib fracture. | 26756408 |
| Alzheimers Disease", Inflammation | Altered Intercellular Communication | Cerebrospinal Fluid Alzheimer's Disease Biomarkers in Cerebral Amyloid Angiopathy-Related Inflammation. | 26757185 |
| Respiratory Distress Syndrome, Adult, Pneumonitis, Respiratory Distress Syndrome, Newborn | Altered Intercellular Communication | Leukocyte-mediated pulmonary inflammation is a key pathophysiological mechanism involved in acute respiratory distress syndrome (ARDS). | 26757701 |
| Inflammation | Altered Intercellular Communication | Here, we approach this problem from an immunological perspective by examining CD19(+)CD24(hi)CD38(hi) B cells, an important participant in acute and chronic inflammation. | 26758063 |
| Inflammation, Acute Coronary Syndrome | Altered Intercellular Communication | Influence of pre-existing inflammation on the outcome of acute coronary syndrome: a cross-sectional study. | 26758266 |
| Inflammation, Acute Coronary Syndrome, Coronary Artery Disease, GDC AJCC Clinical Stage Terminology | Altered Intercellular Communication | Inflammation is a well-established risk factor for the development of coronary artery disease (CAD) and acute coronary syndrome (ACS). | 26758266 |
| Inflammation, Acute myocardial infarction, Angina, Unstable, GDC AJCC Clinical Stage Terminology | Altered Intercellular Communication | The aim of this study was to determine if blood biomarkers of inflammation were associated specifically with acute myocardial infarction (MI) or unstable angina (UA) in patients with ACS. | 26758266 |
| Inflammation, Chest Pain, GDC AJCC Clinical Stage Terminology | Altered Intercellular Communication | When adjusted for smoking, age, sex and duration of chest pain, concentrations of plasma biomarkers of inflammation (high-sensitivity C reactive protein>2 mg/L (OR=1.40 (1.00 to 1.96) and fibrinogen (p for trend=0.035)) analysed at admission were found to be associated with MI over UA, in an event of ACS. | 26758266 |
| Inflammation, GDC AJCC Clinical Stage Terminology | Altered Intercellular Communication | Our results show that, in patients with ACS, the blood cell profile and degree of inflammation at admission was associated with the outcome. | 26758266 |
| Inflammation | Altered Intercellular Communication | Furthermore, our data suggest that a pre-existing low-grade inflammation may dispose towards MI over UA. | 26758266 |
| Inflammation, Gastritis | Altered Intercellular Communication | Association between serum levels of high sensitive C-reactive protein and inflammation activity in chronic gastritis patients. | 26758551 |
| Inflammation, Gastritis | Altered Intercellular Communication | This study aimed to determine any relationship between high sensitive C-reactive protein (hs-CRP) and inflammation activity among patients with gastritis. | 26758551 |
| Inflammation | Altered Intercellular Communication | The relation between active inflammation and other variables was evaluated by logic link function model. | 26758551 |
| Inflammation | Altered Intercellular Communication | The prevalence of mild, moderate and severe inflammation activities was 66.5%, 23.8% and 9.6% respectively. | 26758551 |
| Inflammation | Altered Intercellular Communication | Relationship between hs-CRP and inflammation activities (p < 0.01) was significant. | 26758551 |
| Inflammation, Plaque, Amyloid, neuron death, Data types - Address | Altered Intercellular Communication | We aimed at deciphering the modifications occurring in vivo during the very early stages of AD, before the development of amyloid deposits, neurofibrillary tangles, neuronal death and inflammation. | 26759118 |
| Refractory anemias, Inflammation, Rheumatoid Arthritis, Infiltration | Altered Intercellular Communication | Synovial infiltration of monocytes is commonly associated with inflammation in rheumatoid arthritis (RA). | 26759164 |
| Refractory anemias, Inflammation | Altered Intercellular Communication | Toll-like receptors (TLRs) are innate sensors that recognize cell debris and microbial components in host, a process contributing to maintain chronic inflammation in RA. | 26759164 |
| Inflammation, Vascular Diseases, Muscle (organ) | Altered Intercellular Communication | In addition to being a fatal complication, clinicians should be aware of these complications, as immunosuppression used to control the muscular and cutaneous inflammation may not control the GI vasculopathy. | 26759443 |
| methyldopa, Inflammation, Apoptosis of neurons | Altered Intercellular Communication | Inflammation and oxidative stress are involved in age-related macular degeneration (AMD) and possibly associated with an activation of neuronal apoptosis inhibitor protein/class II transcription activator of the Major Histocompatibility Complex (MHC)/heterokaryon incompatibility/telomerase-associated protein 1, leucine-rich repeat or nucleotide-binding domain, leucine-rich repeat-containing family, and pyrin domain-containing 3 (NLRP3) inflammasome. | 26760997 |
| Inflammation, Toxic effect | Altered Intercellular Communication | RT can induce cytokine responses that could play a role in mediating radiation toxicity by increasing inflammation. | 26761561 |
| Inflammation, Bipolar Disorder | Altered Intercellular Communication | The Predictive Value of Depressive Symptoms for All-Cause Mortality: Findings From the PRIME Belfast Study Examining the Role of Inflammation and Cardiovascular Risk Markers. | 26761713 |
| Inflammation | Altered Intercellular Communication | The level of protein expression appears to be different between muscle, knee joint and serum, suggesting that inflammation is regulated differently within these tissues. | 26762130 |
| Degenerative polyarthritis, Inflammation | Altered Intercellular Communication | While IL-15 protein expression in the muscle was lower in the knee OA group, no correlation was found between the expression of IL-15 protein in the muscle, joint and serum, which suggests that inflammation is regulated differently within these tissues. | 26762130 |
| Sepsis, Respiratory Failure, diabetic | Altered Intercellular Communication | A case report of a 68-year-old male obese diabetic patient with an abscess of left femoral region, and diffuse inflammation of abdominal wall and genital region developing sepsis, respiratory and renal failure. | 26762496 |
| Inflammation, Ocular Motility Disorders | Altered Intercellular Communication | Blueberries have been recognized to possess protective properties from inflammation and various diseases, but not for eye and ocular disorders. | 26762881 |
| Inflammation, Dryness (characteristic) | Altered Intercellular Communication | Our findings demonstrate that PS protects human cornea from hyperosmolarity-induced inflammation and oxidative stress, suggesting protective effects of PS on dry eye. | 26762881 |
| Atrial Fibrillation, Inflammation | Altered Intercellular Communication | These results demonstrate for the first time a dependency of MPAs and CD11b expression on monocytes in the presence of AF and support the notion of a close relationship between AF, thrombogenesis and inflammation. | 26763077 |
| vascular inflammations, Vascular calcification | Altered Intercellular Communication | This study investigated noncoronary vascular calcification and its influence on changes in vascular inflammation. | 26764069 |
| vascular inflammations, Calcinosis | Altered Intercellular Communication | Finally, baseline calcification was related to changes in vascular inflammation. | 26764069 |
| vascular inflammations, Calcinosis, Vascular calcification | Altered Intercellular Communication | The presence of vascular calcification at baseline is associated with progressive calcification; in the carotid arteries, calcification appears to influence vascular inflammation. | 26764069 |
| Calcinosis, Atherosclerosis | Altered Intercellular Communication | Atherosclerosis is an inflammatory condition with calcification apparent late in the disease process. | 26764069 |
| Inflammation, Primary malignant neoplasm, vinyltriethoxysilane | Altered Intercellular Communication | In this prospective cohort study of 1,070 cancer patients, decreased serum albumin was a marker for risk of VTE and mortality, independent of kidney or liver function and inflammation markers. | 26764252 |
| Inflammation, Presenile dementia, Coronary heart disease, Cerebrovascular accident, Diabetes Mellitus, Non-Insulin-Dependent | Altered Intercellular Communication | Past research has linked low socio-economic status (SES) to inflammation, metabolic dysregulation, and various chronic and age-related diseases such as type 2 diabetes, coronary heart disease, stroke, and dementia. | 26765221 |
| Inflammation, Osage language, Cardiovascular Diseases, Hypoxia, Sleep Apnea, Obstructive | Altered Intercellular Communication | Obstructive sleep apnea (OSA), characterized by repetitive episodes of apnea/hypopnea and hypoxia, is associated with systemic inflammation and induces metabolic, endocrine, and cardiovascular diseases. | 26765405 |
| Neurodegenerative Disorders, Inflammation | Altered Intercellular Communication | Inflammation might have an impact on neurodegenerative diseases. | 26765405 |
| Inflammation, Primary malignant neoplasm, Neoplasms, Hypercalcemia, CTCAE, Weight decreased | Altered Intercellular Communication | Serum PTHrP Predicts Weight Loss in Cancer Patients Independent of Hypercalcemia, Inflammation, and Tumor Burden. | 26765580 |
| Inflammation, Hypercalcemia, CTCAE, Neoplasms | Altered Intercellular Communication | Serum PTHrP levels predicted cancer-associated WL independent of the presence of hypercalcemia, inflammation, tumor burden, and other comorbidities. | 26765580 |
| Arteritis | Altered Intercellular Communication | Brain large artery inflammation associated with HIV and large artery remodeling. | 26765935 |
| Inflammation | Altered Intercellular Communication | To test the hypothesis that brain arteries from HIV+ cases have a greater degree of inflammation than brain arteries from HIV- cases, and that inflammation is associated with brain arterial remodeling. | 26765935 |
| Inflammation, herpesvirus 3, human | Altered Intercellular Communication | Arteries from HIV+ cases had a higher inflammation score (B = 0.36, P = 0.05) compared with arteries from HIV- cases, although the association was attenuated after controlling for demographic variables, vascular risk factors, and latent VZV (B = 0.20, P = 0.18). | 26765935 |
| Inflammation | Altered Intercellular Communication | Although intimal inflammation was similar in cases with and without HIV, adventitial inflammation was associated with HIV. | 26765935 |
| Inflammation, Intracranial Atherosclerosis | Altered Intercellular Communication | Intimal inflammation was associated with intracranial atherosclerosis independent of HIV status, but adventitial inflammation was associated with HIV-associated dolichoectasia in arteries with a thin media. | 26765935 |
| Inflammation, Intracranial Atherosclerosis, Vertebrobasilar Dolichoectasia | Altered Intercellular Communication | Adventitial inflammation is associated with HIV and dolichoectasia independent of intracranial atherosclerosis. | 26765935 |
| Inflammation | Altered Intercellular Communication | Ly6C+ monocytes from old (18-22 mo) mice and CD14+CD16+ intermediate/inflammatory monocytes from older adults also contributed to this "age-associated inflammation" as they produced more of the inflammatory cytokines IL6 and TNF in the steady state and when stimulated with bacterial products. | 26766566 |
| Inflammation | Altered Intercellular Communication | Thus, with age TNF impairs inflammatory monocyte development, function and promotes premature egress, which contribute to systemic inflammation and is ultimately detrimental to anti-pneumococcal immunity. | 26766566 |
| Inflammation, Neoplasms | Altered Intercellular Communication | Tumour budding with and without admixed inflammation: two different sides of the same coin? | 26766735 |
| Inflammation, Primary malignant neoplasm | Altered Intercellular Communication | Marked overall peritumoural inflammation has been associated with favourable outcome and may lead to the presence of isolated cancer cells due to destruction of invading cancer cell islets. | 26766735 |
| Inflammation, Colorectal Carcinoma, Neoplasms | Altered Intercellular Communication | We assessed the prognostic significance of tumour budding and peritumoural inflammation in a cohort of 381 patients with CRC applying univariate and multivariate analyses. | 26766735 |
| Inflammation, Primary malignant neoplasm | Altered Intercellular Communication | Scattering of invading cancer cell islets by marked overall peritumoural inflammation seems to have a minor role. | 26766735 |
| Inflammation, septic, Cerebral dysfunction | Altered Intercellular Communication | We hypothesized that in non-severe septic patients, blood biomarkers of inflammation, endothelial activation, coagulation, and brain function would be different when compared to patients with and without brain dysfunction. | 26768428 |
| Steatohepatitis, Fibrosis Assessment, Inflammation | Altered Intercellular Communication | The Distribution of Liver Steatosis, Fibrosis, Steatohepatitis and Inflammation Activity in Alcoholics According to FibroMax Test. | 26768633 |
| Necrotizing granulomatous inflammation, Bone Tuberculosis | Altered Intercellular Communication | The diagnosis was confirmed as tubercular osteomyelitis after the biopsy, which showed chronic granulomatous inflammation, and the culture was positive for Mycobacterium tuberculosis. | 26768706 |
| Paresis, Myositis, CTCAE 5.0, Myositis | Altered Intercellular Communication | The inclusion body myositis is an inflammatory myopathy that leads to chronic muscle inflammation associated with muscle weakness. | 26768933 |
| Inflammation, Blood Clot, Hypoxia | Altered Intercellular Communication | This might be accounted for by factors such as hypoxia, thrombus formation, increased vasoendothelial growth factor release and inflammation affecting both the visible retinal and the unobserved cerebral microvasculature. | 26771382 |
| Inflammation, Diabetes Mellitus, Non-Insulin-Dependent | Altered Intercellular Communication | Therefore, our data reveal that PTB-DM or LTB-DM is characterized by alterations in the systemic levels of adipocytokines, indicating that altered adipose tissue inflammation underlying Type 2 diabetes potentially contributes to pathogenesis of TB disease. | 26771473 |
| Inflammation, Prostate carcinoma | Altered Intercellular Communication | Key genes involved in the immune response are generally not associated with intraprostatic inflammation in men without a prostate cancer diagnosis: Results from the prostate cancer prevention trial. | 26771888 |
| Inflammation, Prostate carcinoma | Altered Intercellular Communication | We previously reported that both intraprostatic inflammation and SNPs in genes involved in the immune response are associated with prostate cancer risk and disease grade. | 26771888 |
| Inflammation | Altered Intercellular Communication | After creating a genetic risk score from the three SNPs possibly associated with inflammation, the odds of inflammation increased with increasing number of risk alleles (P-trend = 0.008). | 26771888 |
| Inflammation, Prostate carcinoma | Altered Intercellular Communication | While our findings do not generally support a cross-sectional link between individual SNPs in key genes involved in the immune response and intraprostatic inflammation in men without a prostate cancer diagnosis, they do suggest that some of these variants when in combination may be associated with intraprostatic inflammation in benign tissue. | 26771888 |
| Inflammation, atherosclerotic | Altered Intercellular Communication | Inflammation is involved in all stages of development of atherosclerotic plaques. | 26771969 |
| Interstitial inflammation | Altered Intercellular Communication | Despite lack of active urinary tract infection, interstitial inflammation was more prevalent in struvite SFs compared to CaOx SFs (43.5% vs 7.3%, P = .0001). | 26772639 |
| Inflammation, Dental Plaque | Altered Intercellular Communication | Struvite SFs have less plaque formation than CaOx SFs, but demonstrate evidence of severe parenchymal inflammation compared to other SFs. | 26772639 |
| Interstitial inflammation | Altered Intercellular Communication | The role of this prominent interstitial inflammation requires further study. | 26772639 |
| Inflammation | Altered Intercellular Communication | The constitutive inflammation that characterizes advanced age is termed inflamm-aging. | 26772806 |
| Inflammation | Altered Intercellular Communication | The constitutive inflammation that characterizes advanced age is termed inflamm-aging. | 26772806 |
| Inflammation | Altered Intercellular Communication | Testosterone associated inversely with weight, the degree of inflammation (i.e. | 26772984 |
| Sepsis, Inflammation | Altered Intercellular Communication | The results of our study provide indirect hint that control of inflammation is a major therapeutic approach in sepsis, and may facilitate to ameliorate the progressive cardiovascular collapse. | 26772992 |
| Inflammation, Non-alcoholic Fatty Liver Disease | Altered Intercellular Communication | These results suggested that adzuki beans attenuate lipid accumulation and oxidative stress-induced inflammation by suppressing hepatic messenger RNA expression of lipogenic and inflammatory mediators in NAFLD. | 26773785 |
| Pneumonitis | Altered Intercellular Communication | Previously, in an experimental animal model, we found that simvastatin (Sv) pretreatment was effective in preventing ROFA induced lung inflammation. | 26773838 |
| Vasculitis, Dental Leakage | Altered Intercellular Communication | Microvascular inflammation in 5xFAD mice presented with sporadic FITC-albumin leakages at M4 becoming more prevalent at M9 and M12. | 26774030 |
| Cerebral Amyloid Angiopathy, Vasculitis, Dental Plaque | Altered Intercellular Communication | Cerebral amyloid angiopathy and microvascular inflammation occur in 5xFAD mice concomitantly to parenchymal plaque deposition. | 26774030 |
| Inflammation, Infection caused by Helicobacter pylori | Altered Intercellular Communication | Peptic ulceration connected with chronic inflammation in gastrointestinal mucosa could be induced by Helicobacter pylori infection. | 26774268 |
| Tumor necrosis, Inflammation | Altered Intercellular Communication | Tumor necrosis factor alpha (TNF-a) encoded by TNFA gene is a key mediator in the inflammation process. | 26774268 |
| Airway structure, Asthma | Altered Intercellular Communication | Bronchial asthma is characterised by airway inflammation and remodelling with a decline of lung function. | 26774356 |
| Inflammation, Obesity | Altered Intercellular Communication | Obesity is characterised by chronic, low-grade systemic inflammation. | 26774499 |
| Airway structure, Asthma, Lung diseases | Altered Intercellular Communication | Elevated FeNO levels reflect airway inflammation in various lung diseases including asthma. | 26774499 |
| Endocrine System Diseases, Traumatic injury, Hereditary | Altered Intercellular Communication | The exact etiology remains unclear, but trauma, hormonal disturbances, pregnancy, genetic and hereditary factors are postulated to be in association with its' development. | 26774632 |
| Inflammation, Malnutrition | Altered Intercellular Communication | Serum pregnancy-associated plasma protein A correlates with inflammation and malnutrition in patients treated with maintenance hemodialysis. | 26774806 |
| Bone Diseases, Anemia, Chronic Kidney Diseases | Altered Intercellular Communication | Advanced chronic kidney disease (CKD) leads to complications such as anemia, electrolyte abnormalities, bone and mineral disorder, and malnutrition-inflammation-atherosclerosis (MIA) syndrome, that result in high cardiovascu- lar mortality. | 26774806 |
| Inflammation | Altered Intercellular Communication | One of the biomarkers associated with inflammation and cardiovascular events is pregnancy-associated plasma protein A (PAPP-A). | 26774806 |
| Inflammation, Malnutrition | Altered Intercellular Communication | It positively correlated with N-terminal pro-brain natriuretic peptide (NT-proBNP), serum sodium, and the markers of inflammation and malnutrition. | 26774806 |
| Seizures, Acute inflammation, Rasmussen Syndrome | Altered Intercellular Communication | Absence of seizures in Rasmussen encephalitis with active inflammation. | 26775150 |
| Seizures, Inflammation, Neurologic Deficits, Epilepsy | Altered Intercellular Communication | Our patient's quite remarkable neurologic deficits along with active inflammation in the absence of epilepsy supports that, at least in some individuals, unilateral hemispheric progressive inflammation can occur without active seizure activity. | 26775150 |
| TNM Staging System, Rupture | Altered Intercellular Communication | Receipt of mitotane was associated with hormonal secretion (58% vs 32%; p = 0.001), advanced TNM stage (stage IV: 42% vs 23%; p = 0.021), adjuvant chemotherapy (37% vs 5%; p < 0.001), and adjuvant radiation (17% vs 5%; p = 0.01), but was not associated with tumor rupture, margin status, or N-stage. | 26775162 |
| Vascular Diseases, Inflammation | Altered Intercellular Communication | Furthermore, we tested whether (1) cognitive slowing and (risk factors for) vascular diseases, (2) a marker of chronic inflammation, and (3) specific somatic conditions could explain this association. | 26775581 |
| Inflammation, Degenerative polyarthritis, Chronic Obstructive Airway Disease, Chronic disease, Comorbidity | Altered Intercellular Communication | Specific somatic comorbidity (number of chronic diseases, chronic obstructive pulmonary disease, osteoarthritis) or inflammation influenced the odds ratio. | 26775581 |
| Inflammation, Asthma | Altered Intercellular Communication | Eosinophilic inflammation is frequently associated with increased asthma severity. | 26775606 |
| Inflammation | Altered Intercellular Communication | Association of synovial inflammation and inflammatory mediators with glenohumeral rotator cuff pathology. | 26775747 |
| Inflammation | Altered Intercellular Communication | We hypothesized that patients with full-thickness rotator cuff tears would have greater synovial inflammation compared with those without rotator cuff tear pathology, with gene expression relating to histologic findings. | 26775747 |
| Tears body substance, Inflammation | Altered Intercellular Communication | Patients with full-thickness rotator cuff tears have greater levels of synovial inflammation, angiogenesis, and MMP-3 upregulation compared with controls. | 26775747 |
| Iron deficiency anemia, Inflammation, Anemia, idarubicin | Altered Intercellular Communication | Of the 2401 participants, 18.9% had anaemia, 1.9% had anaemia related to inflammation (AI), and 1.3% had iron-deficiency anaemia (IDA). | 26775754 |
| Necrotizing granulomatous inflammation, Inflammation, Abscess, Pseudoepitheliomatous hyperplasia | Altered Intercellular Communication | The most common histopathological findings were chronic granulomatous inflammation, suppurative inflammation, sinus and abscess formation, pseudoepitheliomatous hyperplasia, transepidermal elimination and scarring. | 26776602 |
| Arterial Stiffness, Inflammation, Diabetes Mellitus | Altered Intercellular Communication | Low-Grade Inflammation and Increased Arterial Stiffness in Chinese Youth and Adolescents with Newly-Diagnosed Type 2 Diabetes Mellitus. | 26777037 |
| Arterial Stiffness, Inflammation, Diabetes Mellitus, Non-Insulin-Dependent | Altered Intercellular Communication | To investigate the relationship between low-grade inflammation (LI) and increased arterial stiffness in Chinese youth and adolescents with newly-diagnosed type 2 diabetes mellitus (T2DM). | 26777037 |
| Inflammation | Altered Intercellular Communication | Ninety-eight subjects aged 10 to 24 years with newly-diagnosed T2DM were investigated for findings of general inflammation. | 26777037 |
| Hypersensitivity | Altered Intercellular Communication | These findings suggest that Resveratrol as a therapeutic agent could inhibit PGD2-mediated inflammation but would be ineffective against histamine-mediated allergic reactions. | 26777630 |
| allergic inflammation | Altered Intercellular Communication | However, Resveratrol could potentially exacerbate or promote allergic inflammation by enhancing IgE-dependent TNF production from mast cells in human skin. | 26777630 |
| Inflammation, Pulmonary Hypertension | Altered Intercellular Communication | Serum levels of interleukin-18-binding protein isoform a: Clinical association with inflammation and pulmonary hypertension in systemic sclerosis. | 26777734 |
| Inflammation, Sample Size Calculation, Pulmonary Hypertension | Altered Intercellular Communication | These results suggest that the inhibition of IL-18 signaling by IL-18BPa may be involved in the development of pulmonary vascular involvement leading to pulmonary hypertension and modulate the systemic inflammation in SSc. | 26777734 |
| Communicable Diseases, Inflammation, Neoplasms, Paralysed | Altered Intercellular Communication | Acute flaccid paralysis is associated with inflammation, infection, or tumors in the spinal cord or peripheral nerves. | 26778096 |
| Inflammation, Nonarteritic anterior ischemic optic neuropathy (NAION), Thrombophilia, Atherosclerosis | Altered Intercellular Communication | Associations between thrombophilic risk factors and determinants of atherosclerosis and inflammation in patients with non-arteritic anterior ischaemic optic neuropathy. | 26778257 |
| Inflammation, Thrombophilia, Atherosclerosis | Altered Intercellular Communication | We analyzed thrombophilic risk factors and determinants of atherosclerosis and inflammation in 109 consecutive patients and 109 age- and sex-matched volunteers using a case-control design. | 26778257 |
| Inflammation | Altered Intercellular Communication | Inflammation influences cognitive development in infants and older adults, however, how inflammation may affect academic development during childhood and adolescence remains to be elucidated. | 26778777 |
| Degenerative polyarthritis, Inflammation | Altered Intercellular Communication | Latest data suggests that inflammation plays a critical role in the pathogenesis of OA. | 26780447 |
| Degenerative polyarthritis, Inflammation | Altered Intercellular Communication | Blood neutrophil-lymphocyte ratio (NLR) is a simple non-invasive and cost-effective marker of inflammation in various systemic diseases, but it has not been investigated in OA yet. | 26780447 |
| Refractory anemias, Inflammation, Osteoporosis | Altered Intercellular Communication | We herein assessed serum FGF23 and its relationship to inflammation and osteoporosis in patients with RA. | 26781009 |
| Refractory anemias, Inflammation | Altered Intercellular Communication | Conclusion In patients with RA, serum FGF23 is correlated with inflammation, the disease activity of RA, and bone absorption markers. | 26781009 |
| Inflammation | Altered Intercellular Communication | Serum FGF23 may be associated with abnormal bone absorption related to RA inflammation. | 26781009 |
| Inflammation, Necrosis, Fibrosis Assessment, Mesenteric Panniculitis, Hyperplastic Polyp | Altered Intercellular Communication | Mesenteric panniculitis (MP) is a benign fibroinflammatory process characterized by the presence of fat necrosis, chronic inflammation and fibrosis in the mesentery. | 26781011 |
| Malignant Neoplasms | Altered Intercellular Communication | Although various causal factors, such as malignancy, chronic inflammatory conditions and autoimmune processes, have been identified, the precise etiology remains unknown. | 26781011 |
| ARCN1 gene, Inflammation, Chronic Obstructive Airway Disease | Altered Intercellular Communication | Chronic obstructive pulmonary disease (COPD) is characterized by progressive airflow limitation and inflammation. | 26781464 |
| Diabetes Mellitus, Atherosclerosis | Altered Intercellular Communication | Parathyroid hormone is associated with incident diabetes in white, but not black adults: The Atherosclerosis Risk in Communities (ARIC) Study. | 26782010 |
| Refractory anemias, Rheumatoid Arthritis, destruction joint, Inflammation | Altered Intercellular Communication | Rheumatoid arthritis (RA) is characterized by chronic synovial inflammation and subsequent joint destruction. | 26782362 |
| Prostate carcinoma, prostatitis | Altered Intercellular Communication | Greater extent of prostate inflammation in negative biopsies is associated with lower risk of prostate cancer on repeat biopsy: results from the REDUCE study. | 26782712 |
| Prostate carcinoma, prostatitis, Structure of posterior cerebral artery | Altered Intercellular Communication | To evaluate whether the extent of baseline acute prostate inflammation (API) and chronic prostate inflammation (CPI) was associated with risk of prostate cancer (PCa) at 2-year repeat prostate biopsy in a clinical trial with systematic biopsies independent of PSA. | 26782712 |
| Inflammation, Chronic heart failure | Altered Intercellular Communication | Nutritional Status is Associated with Inflammation and Predicts a Poor Outcome in Patients with Chronic Heart Failure. | 26782970 |
| Inflammation, Atherosclerosis, Congestive heart failure | Altered Intercellular Communication | These data indicate that a poor nutritional status as assessed using the CONUT score and atherosclerosis as indicated by CIMT is significantly associated with inflammation and predicts poor outcomes in patients with CHF. | 26782970 |
| Inflammation, Colitis | Altered Intercellular Communication | Most colonoscopies showed ulcerations involving the rectum and sigmoid, 66% of patients had extensive colitis, 55% had patchy distribution and 20% had ileal inflammation. | 26783344 |
| Inflammation, FAM126A gene | Altered Intercellular Communication | Serum IL-10 and IL-12 were elevated significantly with disease progression (P < 0.0001) and a positive correlation coefficient was detected between IL-10, IL-12 (r = 0.785, P < 0.0001), and transaminase values suggesting their possible role in chronic inflammation progression leading to HCC. | 26783377 |
| Inflammation, FAM126A gene | Altered Intercellular Communication | IL-10 and IL-12 might be involved in chronic inflammation progression leading to HCC and their evaluation could be used as new biomarkers to reflect the degree of inflammation in HCC development. | 26783377 |
| Psoriasis | Altered Intercellular Communication | Consistently, in human psoriasis and in a mouse model of a psoriasis-like skin inflammation, epidermal vaspin expression was significantly down-regulated. | 26783881 |
| Psoriasis | Altered Intercellular Communication | Down-regulation of vaspin in KCs resulted in decreased expression of differentiation-associated genes and up-regulation of interferon-inducible and inflammation-associated psoriasis signature genes. | 26783881 |
| Myeloid Progenitor Cells | Altered Intercellular Communication | Consequently, the application of vaspin inhibited myeloid cell infiltration in a mouse model of a psoriasis-like skin inflammation. | 26783881 |
| Tissue damage, Inflammation | Altered Intercellular Communication | MIF reflects tissue damage rather than inflammation in post-cardiac arrest syndrome in a real life cohort. | 26784134 |
| Orbital Pseudotumor | Altered Intercellular Communication | The authors describe a case of a 61-year-old woman, initially diagnosed with idiopathic orbital inflammation refractory to multiple immunosuppressive agents. | 26784550 |
| Corneal epithelial defect, Inflammation, Xerophthalmia | Altered Intercellular Communication | He exhibited bilateral conjunctival xerosis with complete corneal melt in the right eye and a large corneal epithelial defect with underlying anterior chamber inflammation in the left eye. | 26785304 |
| Inflammation, Hypoxia | Altered Intercellular Communication | Furthermore, they delineate the relationship of measurable tissue hypoxia within the STK and markers of inflammation in human ARAS. | 26787779 |
| Inflammation, Hypertrophy | Altered Intercellular Communication | Increased expression of receptor for advanced glycation end products (RAGE) in adipose tissue has been associated with inflammation, adipocyte hypertrophy, and impaired insulin signal. | 26788516 |
| Airway structure, Allergic asthma, Exacerbation, Symptoms | Altered Intercellular Communication | Omalizumab, an anti-immunoglobulin E (IgE) monoclonal antibody, inhibits the binding of circulating IgE to mast cells and basophils, resulting in fewer episodes of airway inflammation, asthma symptoms and exacerbations in patients with severe allergic asthma. | 26790100 |
| Diabetes with coma (disorder), Inflammation | Altered Intercellular Communication | Laboratory data suggested acute inflammation and hyperosmolar hyperglycemic syndrome. | 26790763 |
| Inflammation | Altered Intercellular Communication | The patient was finally discharged after complete recovery from severe inflammation. | 26790763 |
| Inflammation, Hemoptysis | Altered Intercellular Communication | After 48 h, the patient became unwell with frank haemoptysis and features of systemic inflammation. | 26791127 |
| Diabetic Retinopathy, Inflammation | Altered Intercellular Communication | "Association between platelet activating factor acetylhydrolase and diabetic retinopathy: Does inflammation affect the retinal status?". | 26791393 |
| Degenerative polyarthritis, Inflammation | Altered Intercellular Communication | Galectin-1 Couples Glycobiology to Inflammation in Osteoarthritis through the Activation of an NF-kB-Regulated Gene Network. | 26792806 |
| Degenerative polyarthritis, Inflammation, Degenerative disorder of cartilage | Altered Intercellular Communication | Because inflammation is critical to cartilage degeneration in osteoarthritis, this report reveals an intimate relation of glycobiology to osteoarthritic cartilage degeneration. | 26792806 |
| Granulomatous inflammation, Focal necrosis, Vasculitis, CTCAE | Altered Intercellular Communication | A right nasal biopsy was performed which revealed granulomatous inflammation with focal necrosis and vasculitis. | 26793412 |
| Encephalitis, Inflammation | Altered Intercellular Communication | Encephalitis is a brain inflammation, which could involve also the meninges. | 26793848 |
| Lipogranuloma | Altered Intercellular Communication | Adult-onset xanthogranuloma (AOX) of the corneoscleral limbus is a rare inflammatory condition of unknown aetiology. | 26794218 |
| Inflammation, Chronic Kidney Diseases | Altered Intercellular Communication | In conclusion, higher mtDNA copy number associated with lower incidence of CKD independent of traditional risk factors and inflammation biomarker levels in this cohort. | 26794963 |
| Inflammation | Altered Intercellular Communication | As GDF-15 is a marker of chronic inflammation and oxidative stress, our finding of increased serum GDF-15 in patients with NP supports the hypothesis that its pathogenesis involves chronic inflammation and oxidative stress. | 26795264 |
| Inflammation, Cyclophosphamide/Vincristine/Dacarbazine Regimen, Cardiovascular Diseases | Altered Intercellular Communication | We sought to evaluate the relationship between (18)F-FDG uptake in supraclavicular BAT in relation to arterial inflammation and subsequent cardiovascular disease (CVD) events in humans. | 26795284 |
| Arteritis | Altered Intercellular Communication | BAT activity negatively correlated with arterial inflammation (r = -0.178, P < 0.01), a relationship that persisted after correcting for age and BMI (r = -0.147, P < 0.01). | 26795284 |
| Arteritis | Altered Intercellular Communication | Our results suggest that increased supraclavicular BAT activity is inversely associated with arterial inflammation, independently of age and BMI. | 26795284 |
| Communicable Diseases, Inflammation, Malignant Neoplasms | Altered Intercellular Communication | The most common large-bowel pathologies included malignancy (51%), inflammation (15%), and infection (15%). | 26795889 |
| Communicable Diseases, Inflammation | Altered Intercellular Communication | This might be that the antimicrobial PHMB component of the novel dressing played a role to reduce infection and inflammation reaction. | 26796543 |
| Vascular Diseases, Malignant Neoplasms | Altered Intercellular Communication | Specific note was made of cases with active malignancy, vascular disorders, or inflammatory conditions with an increased risk of vasculopathy. | 26797023 |
| Granulomatous inflammation | Altered Intercellular Communication | Histologically, numerous eggs of F. hepatica were noted with acute and chronic granulomatous inflammations in the subserosa and pericolic adipose tissues. | 26797440 |
| Inflammation, Diabetes, Autoimmune | Altered Intercellular Communication | Administration with SGAD65190-315 /IL-10 blocked the onset of autoimmune diabetes in NOD mice, significantly suppressed islet inflammation, inhibited the apoptosis of islet b cells, induced immune tolerance to autoantigen GAD65 and proinsulin and shifted the Th1/Th2 balance towards Th2. | 26797873 |
| Inflammation, Toxic effect | Altered Intercellular Communication | At 30 mg, a dose-limiting toxicity (grade III mucosal inflammation) was observed. | 26798966 |
| Inflammation, Neoplasms | Altered Intercellular Communication | Under different inflammation states, proinflammatory cytokine intensity, in addition to tumor stage, independently predicted PFSR in patients with CRP <5 mg/L, whereas tumor stage was the only independent predictor of PFSR in patients with CRP >=5 mg/L. | 26799163 |
| Inflammation, Polypoidal choroidal vasculopathy, Humor | Altered Intercellular Communication | The Features of Inflammation Factors Concentrations in Aqueous Humor of Polypoidal Choroidal Vasculopathy. | 26799405 |
| Inflammation, Necrosis | Altered Intercellular Communication | A necrotic background with paucity of inflammation was frequently seen in lung FNA. | 26800146 |
| Inflammation, Arthritis, Periodontitis | Altered Intercellular Communication | We examined the efficacy of ProCT and hsCRP as biomarkers of periodontitis in the saliva and serum of patients with arthritis, which is characterized by variable levels of systemic inflammation that potentially can confound the interpretation of inflammatory biomarkers. | 26800284 |
| Refractory anemias, Inflammation, Periodontitis, Degenerative polyarthritis | Altered Intercellular Communication | Any elevation in salivary and serum hsCRP due to periodontitis apparently was overshadowed by differences among these patients in factors that influence CRP, such as the extent of inflammation between RA and OA, the extent of adipose tissue, the use of anti- inflammatory medications and smoking status. | 26800284 |
| Inflammation, Glaucoma, CTCAE | Altered Intercellular Communication | Because no inflammation was present upon examination, we observed the patient without prescribing any additional medications except for the eye drop treatment for glaucoma. | 26800888 |
| Hepatobiliary Disorder | Altered Intercellular Communication | The liver disease (D) variable did not account for four patients with inflammation/cirrhosis. | 26801328 |
| Crohn Disease | Altered Intercellular Communication | MicroRNA-124 Promotes Intestinal Inflammation by Targeting Aryl Hydrocarbon Receptor in Crohn's Disease. | 26802080 |
| Gastrointestinal inflammation | Altered Intercellular Communication | These findings suggest that miR-124 induces intestinal inflammation by inhibiting AHR to modulate pro-inflammatory cytokine production and thereby promotes the pathogenesis of CD. | 26802080 |
| Inflammation, MS gene | Altered Intercellular Communication | Differences between adult white and grey matter miRNA expression included higher expression of pro-inflammatory miRNAs in the former, potentially contributing to differences in inflammation between grey and white matter plaques in multiple sclerosis. | 26802178 |
| Inflammation, Dyslipidemias, Atherosclerosis | Altered Intercellular Communication | Dyslipidemia and low-grade inflammation are integral in the pathogenesis of atherosclerosis. | 26803431 |
| Chronic laryngitis, Inflammation, Amyloidosis | Altered Intercellular Communication | Chronic subglottic laryngitis with inflammation or another condition such as amyloidosis was initially suspected. | 26803452 |
| Hemorrhage, Neoplasms, Epistaxis, Acute hemorrhage, Malignant Neoplasms | Altered Intercellular Communication | Altogether 27/52 patients were treated for malignant tumors, 25/52 were attributable to acute haemorrhage due to epistaxis, after tonsillectomy, benign tumors and bleeding attributable to inflammations. | 26803587 |
| Inflammation, Sleep Apnea, Obstructive, Obesity, Osage language | Altered Intercellular Communication | The effect of obesity and medication on the relationship between obstructive sleep apnoea (OSA) and lipidaemia and systemic inflammation is not fully understood for various reasons. | 26804247 |
| airway disease, Inflammation | Altered Intercellular Communication | Neutrophil extracellular traps are associated with inflammation in chronic airway disease. | 26804470 |
| Inflammation, Neoplasms, Gallbladder Carcinoma | Altered Intercellular Communication | The tumor was initially considered to be unresectable locally advanced gallbladder carcinoma with inflammation, and she received 6 courses of chemotherapy with gemcitabine plus cisplatin. | 26805152 |
| Inflammation, Secondary malignant neoplasm of liver, Neoplasms | Altered Intercellular Communication | Subsequently, the inflammation was extinguished, and CT showed the main tumor shrunk and the Glisson's sheath infiltration disappeared; however, a liver metastasis existed in segment 5. | 26805152 |
| Inflammation, Carcinoma | Altered Intercellular Communication | There was carcinoma in situ in the main pancreatic duct surrounding chronic inflammation. | 26805362 |
| Inflammation, Angiolymphoid hyperplasia | Altered Intercellular Communication | Multicentric Castleman disease (MCD) describes a heterogeneous group of disorders involving systemic inflammation, characteristic lymph node histopathology, and multi-organ dysfunction because of pathologic hypercytokinemia. | 26805758 |
| Inflammation, Thrombophilia, Atherosclerosis | Altered Intercellular Communication | We evaluated relationships between DefS, sub-clinical atherosclerosis, low-grade inflammation and hypercoagulation in a bi-ethnic sex cohort. | 26806201 |
| Inflammation, Dental Plaque | Altered Intercellular Communication | Ambulatory BP, vascular structure (left carotid cross-sectional wall area (L-CSWA) and plaque counts), and markers of coagulation and inflammation were quantified. | 26806201 |
| Inflammation, Hypertensive (finding), Dental Plaque, Thrombophilia | Altered Intercellular Communication | A hypertensive state, less plaque, low-grade inflammation, and hypercoagulation were more prevalent in DefS Africans (27-84%) than DefS Caucasians (18-41%). | 26806201 |
| Inflammation, Hyperkinetic, Thrombophilia | Altered Intercellular Communication | Novel findings revealed hypercoagulation, low-grade inflammation and hyperkinetic BP (physiological loss-of-control responses) in DefS African men. | 26806201 |
| Crohns disease of the ileum", Colitis | Altered Intercellular Communication | We report three cases of patients with isolated Crohn's ileitis associated with PSC and in whom colonic inflammation was never documented. | 26806276 |
| Inflammatory Bowel Diseases, Ileitis, Inflammatory disease of mucous membrane | Altered Intercellular Communication | Our three cases of PSC with isolated CD ileitis and long-term follow-up without any sign of colonic involvement argue against the concept that colonic mucosal inflammation is critical for the pathogenesis of PSC in inflammatory bowel disease. | 26806276 |
| Communicable Diseases, Orgasm induced epilepsy | Altered Intercellular Communication | We describe seizure-induced inflammation-like responses and discuss how these changes may be distinguished from those associated with infection. | 26806580 |
| Seizures, Communicable Diseases | Altered Intercellular Communication | We investigated the occurrence of inflammation-like responses, characteristics of the seizures, neurological status at the initial visit, outcomes, and clinical findings to determine the presence of infection. | 26806580 |
| Communicable Diseases | Altered Intercellular Communication | An inflammation-like response was observed in 56.3% of all visits and 19.3% were diagnosed with concurrent infection. | 26806580 |
| Communicable Diseases | Altered Intercellular Communication | Among the visits with inflammation-like response, 34.7% were shown to have an infection. | 26806580 |
| Inflammation, Fibrosis Assessment, Chronic Kidney Diseases, Pathology | Altered Intercellular Communication | Renal fibrosis is a common pathological consequence of chronic kidney disease (CKD) with tissue fibrosis closely associated with chronic inflammation in numerous pathologies. | 26806834 |
| Inflammation, Fibrosis Assessment, Chronic Kidney Diseases | Altered Intercellular Communication | Here, we determine whether there is a molecular link between chronic inflammation and tissue fibrosis in CKD progression. | 26806834 |
| Inflammation, Fibrosis Assessment, Chronic Kidney Diseases | Altered Intercellular Communication | Our study provides insight into molecular mechanisms underlying chronic inflammation and tissue fibrosis and identifies potential therapeutic targets for CKD treatment. | 26806834 |
| Granulomatous inflammation, Sarcoidosis | Altered Intercellular Communication | Microbial genes encoding enzymes that can be targeted by currently available antimycobacterial antibiotics are present in sarcoidosis specimens and localize to sites of granulomatous inflammation. | 26807608 |
| cervical cancer | Altered Intercellular Communication | Adherence to current cervical cancer screening guidelines should minimize the increased risk of CC associated with these hormonal risk factors. | 26808155 |
| Inflammation, Levator palpebrae superioris structure | Altered Intercellular Communication | Levator palpebrae superioris enlargement from inflammation or scar is a factor in thyroid eye disease-related ULR. | 26808176 |
| Inflammation, Fibrosis Assessment, Necrosis | Altered Intercellular Communication | In addition, specimens demonstrated varying degrees of fibrosis (8 cases, 66.7%), necrosis (6 cases, 50%), spongiosis (5 cases, 41.7%), and perifollicular inflammation (6 cases, 50%). | 26808178 |
| Inflammation, Fibrosis Assessment | Altered Intercellular Communication | The MFB has been indicated as a culprit in chronic inflammation and fibrosis. | 26808567 |
| Inflammation | Altered Intercellular Communication | The reduction of HDAC2 expression not only directly enhances the expression of inflammatory genes, but may account for the activation of NF-kB mediated inflammation. | 26809128 |
| Inflammation, Malnutrition, Hematological Disease | Altered Intercellular Communication | Erythrocyte morphology changes not only by primary hematological diseases but also by systemic inflammation, ineffective erythropoiesis and nutritional deficiencies. | 26809230 |
| Inflammation | Altered Intercellular Communication | PET scans indicated increased standardized uptake values, and 7/8 patients were correctly diagnosed with benign inflammation. | 26809651 |
| Vaginitis, Vaginal Diseases | Altered Intercellular Communication | Bacterial vaginosis, aerobic vaginitis, vaginal inflammation and major Pap smear abnormalities. | 26810061 |
| Inflammation, doxorubicin/vincristine protocol, Abnormality of the cervical spine | Altered Intercellular Communication | On the other hand, moderate or severe inflammation (msI) (41.0 % vs. 28.8 %, p = 0,04), moderate or severe AV (msAV) (16.9 % vs. 7.2 %, p = 0.009) and msAV/BV (37.3 % vs. 20.0 %, p = 0.001) were more common in women with such major cervical abnormalities. | 26810061 |
| Communicable Diseases, Dystrophic calcification, Inflammation, Traumatic injury | Altered Intercellular Communication | We present a case of dystrophic calcification occurring entirely within the parotid gland in a 7-year-old girl without apparent inciting inflammation, infection, or trauma. | 26810287 |
| Inflammation, Keratosis | Altered Intercellular Communication | Topical corticosteroid has no influence on inflammation or efficacy after ingenol mebutate treatment of grade I to III actinic keratoses (AK): A randomized clinical trial. | 26810403 |
| Inflammation, Sleep Apnea, Obstructive | Altered Intercellular Communication | Inflammation and oxidative stress play important roles in the pathogenesis of obstructive sleep apnoea syndrome (OSAS). | 26810494 |
| Inflammation | Altered Intercellular Communication | We investigate if Ado system, that plays an important role in central nervous system, in vascular system, and also in inflammation, is involved in pathophysiology of iNPH disease. | 26810542 |
| Inflammation, Pineal germinoma, Demyelinating Diseases | Altered Intercellular Communication | In this report, we describe the case of a 13-year-old boy with a bilateral thalamic germinoma which initially mimicked tumefactive demyelinating disease with inflammation, based on the clinical symptoms, imaging results and histology of a biopsy specimen obtained endoscopically. | 26811911 |
| Inflammation, Opportunistic Infections | Altered Intercellular Communication | These changes may impact clinical outcomes of HF with respect to inflammation, opportunistic infections and physical recovery. | 26812523 |
| Inflammation, Chlamydia trachomatis, Corneal pannus | Altered Intercellular Communication | Can corneal pannus with trachomatous inflammation--follicular be used in combination as an improved specific clinical sign for current ocular Chlamydia trachomatis infection? | 26812948 |
| Trachoma , Perifolliculitis | Altered Intercellular Communication | Mass drug administration (MDA) for trachoma control is administered based on the population prevalence of the clinical sign of trachomatis inflammation - follicular (TF). | 26812948 |
| Ulcerative Colitis, Colitis | Altered Intercellular Communication | IL-36a expression is elevated in ulcerative colitis and promotes colonic inflammation. | 26813344 |
| Inflammatory Bowel Diseases, Psoriasis, Gastrointestinal inflammation | Altered Intercellular Communication | Although significant mechanistic overlap can exist between psoriasis and inflammatory bowel disease (IBD), to date there have been no reports investigating the IL-36 family in gastrointestinal inflammation. | 26813344 |
| Inflammatory disease of mucous membrane | Altered Intercellular Communication | This elevated expression is mirrored in the inflamed colonic mucosa of mice, wherein IL-36 receptor deficiency confirmed this pathway as a mediator of mucosal inflammation. | 26813344 |
| Inflammatory Bowel Diseases, Colitis | Altered Intercellular Communication | These data identify a novel role for IL-36 signaling in colonic inflammation and indicate that the IL-36R pathway may represent a novel target for therapeutic intervention in IBD. | 26813344 |
| Inflammation, Adenocarcinoma, Clear Cell, Neoplasms | Altered Intercellular Communication | We reviewed 109 unselected ovarian clear cell carcinomas for specific tumor characteristics (architecture, nuclear atypia, signet ring cells, stromal hyalinization, background precursor) and inflammatory response (peritumoral lymphocytes found along the leading edge of the tumor, intratumoral stromal inflammation found within the tumor, percentage of plasma cells in the intratumoral stromal inflammation, tumor-infiltrating lymphocytes) and performed immunohistochemistry for all 4 MMR proteins. | 26813747 |
| Chronic lymphocytic inflammation, Pontine structure, Clippers, Inflammatory disorder | Altered Intercellular Communication | Chronic lymphocytic inflammation with pontine perivascular enhancement responsive to steroids (CLIPPERS) is a recently described inflammatory disease of the central nervous system, distinguished by brainstem- and spinal cord-centered lesions with a characteristic contrast enhancement on MRI, a lymphocytic perivascular infiltrate on pathological exam, and a dramatic response to and dependence on steroids therapy. | 26813773 |
| ARCN1 gene, Upper Respiratory Infections | Altered Intercellular Communication | Exhaled and non-exhaled non-invasive markers for assessment of respiratory inflammation in patients with stable COPD and healthy smokers. | 26814886 |
| ARCN1 gene, Chronic Obstructive Airway Disease, Upper Respiratory Infections | Altered Intercellular Communication | We aimed at comparing exhaled and non-exhaled non-invasive markers of respiratory inflammation in patients with chronic obstructive pulmonary disease (COPD) and healthy subjects and define their relationships with smoking habit. | 26814886 |
| ARCN1 gene, Upper Respiratory Infections | Altered Intercellular Communication | An approach combining different types of outcomes can be used for assessing respiratory inflammation in patients with COPD. | 26814886 |
| Inflammation, Metabolic Syndrome X, ETV3 wt Allele | Altered Intercellular Communication | We sought to characterize the relationship between fat radiodensity and quantity in subcutaneous, visceral, and intermuscular fat depots, and its role in inflammation, insulin resistance, and metabolic syndrome (MetS). | 26817938 |
| Inflammation, Ischemia | Altered Intercellular Communication | Similar electrophysiological findings were observed in our study and we propose that this may be due to oxidative stress, and inflammation that occurs secondary to chronic ischemia. | 26818163 |
| Inflammation | Altered Intercellular Communication | Specific members of the RING finger [RNF] protein family serve as E3 ubiquitin ligases and play important roles in the regulation of inflammation. | 26818663 |
| Gastrointestinal inflammation | Altered Intercellular Communication | RNF183 promoted intestinal inflammation via the activation of the NF-kB pathway by increasing the ubiquitination and degradation of IkBa. | 26818663 |
| Gastrointestinal inflammation | Altered Intercellular Communication | RNF183, which is negatively regulated by miR-7, is a novel regulator promoting intestinal inflammation by increasing the ubiquitination and degradation of IkBa, thereby inducing NF-kB activation. | 26818663 |
| Rheumatoid Arthritis, Inflammation | Altered Intercellular Communication | Co-morbidity in patients with early rheumatoid arthritis - inflammation matters. | 26818851 |
| Inflammation, Cardiovascular Diseases | Altered Intercellular Communication | Inflammation is important for the development of cardiovascular disease, but little is known on its relationship with other co-morbidities. | 26818851 |
| Refractory anemias, Inflammation | Altered Intercellular Communication | We investigated the role of inflammation for the development of new comorbidities in early RA. | 26818851 |
| Communicable Diseases, Primary malignant neoplasm, "Richters syndrome | Altered Intercellular Communication | After comprehensive evaluation, the etiology of neurological symptoms was: central nervous system chronic lymphocytic leukemia in 18 patients (10% evaluated by imaging and/or lumbar puncture, 0.4% overall cohort); central nervous system Richter Syndrome in 15 (9% evaluated, 0.3% overall); infection in 40 (23% evaluated, 1% overall); autoimmune/inflammatory conditions in 28 (16% evaluated, 0.7% overall); other cancer in 8 (5% evaluated, 0.2% overall); and another etiology in 63 (37% evaluated, 1.5% overall). | 26819053 |
| Inflammation, Pulmonary Emphysema | Altered Intercellular Communication | Mesenchymal stromal cells (MSCs) may reduce inflammation and promote tissue repair in pulmonary emphysema. | 26819296 |
| Inflammation, Damage | Altered Intercellular Communication | Early recognition is important as ongoing fibrosing inflammation may result in organ damage. | 26819361 |
| Bronchiectasis | Altered Intercellular Communication | Neutrophilic Bronchial Inflammation Correlates with Clinical and Functional Findings in Patients with Noncystic Fibrosis Bronchiectasis. | 26819500 |
| Bronchiectasis, Bronchitis | Altered Intercellular Communication | Neutrophilic bronchial inflammation is a main feature of bronchiectasis, but not much is known about its relationship with other disease features. | 26819500 |
| Inflammation, Colonization | Altered Intercellular Communication | Sputum neutrophilic inflammation and biomarkers of oxidative stress in EBC can be considered good biomarkers of disease severity in NCFB patients, as confirmed by pulmonary function, disease duration, bacterial colonization, BSI score, and exacerbation rate. | 26819500 |
| Anxiety, CTCAE 3.0, Perimenopausal state | Altered Intercellular Communication | Anxiety sensitivity (dimension of psychological concerns) might be an important vulnerability factor in the experience of perimenopausal distress among women closer to menopause, whereas the predisposition to an anxiety response might contribute to perimenopausal distress near the beginning of reproductive hormonal changes. | 26821968 |
| Inflammation, Cardiovascular Diseases, Diabetes Mellitus | Altered Intercellular Communication | Ingenuity pathway analysis and gene set enrichment analysis revealed that inflammation, cardiovascular disease and diabetes signal transduction pathways and amyloid b metabolism were major components of the neuronal response to glutamate excitotoxicity. | 26822027 |
| Diabetic peripheral neuropathy, Diabetes Mellitus, Non-Insulin-Dependent | Altered Intercellular Communication | A high thyroid stimulating hormone level is associated with diabetic peripheral neuropathy in type 2 diabetes patients. | 26822260 |
| Inflammation, Carcinoma | Altered Intercellular Communication | Histology of the resection specimen confirmed active inflammation in the colon and rectum and a carcinoma in situ was identified in the sigmoid colon without invasive growth. | 26822612 |
| Inflammation, MS gene, Cerebral atrophy | Altered Intercellular Communication | Laquinimod had beneficial effects on inflammation, brain atrophy and disease progression in multiple sclerosis (MS) in two phase III clinical trials. | 26823290 |
| Inflammation, Primary malignant neoplasm, Cardiovascular Diseases | Altered Intercellular Communication | Plasma Biomarkers of Inflammation, the Kynurenine Pathway, and Risks of All-Cause, Cancer, and Cardiovascular Disease Mortality: The Hordaland Health Study. | 26823439 |
| Inflammation, Primary malignant neoplasm | Altered Intercellular Communication | In this general population, plasma biomarkers of inflammation and kynurenines were associated with risk of all-cause, cancer, and CVD mortality. | 26823439 |
| Atrial Fibrillation by ECG Finding, Metabolic Syndrome X, Fibrosis Assessment, Rheumatic Heart Disease, Diabetes Mellitus, Obesity, Atrial Fibrillation | Altered Intercellular Communication | Fibroblast growth factor-21 (FGF-21) has been discovered as a strong hormone, plays an important role in lipid metabolism, glucose metabolism, associated with several diseases such as obesity, metabolic syndrome, diabetes mellitus, and cardiovascular events; however, no evidence is available concerning the relationship of FGF-21 and atrial fibrosis in patients with atrial fibrillation (AF) and rheumatic heart disease (RHD). | 26823820 |
| Inflammation, Hyperpigmentation | Altered Intercellular Communication | Biopsy showed groups of apoptotic keratinocytes, basal hyperpigmentation, and slight dermal inflammation. | 26825158 |
| Inflammation, Urticaria, Sweet Syndrome | Altered Intercellular Communication | These 2 histopathologic patterns of ND, early and late, resemble neutrophilic urticarial dermatitis (also known as neutrophilic dermatitis with systemic inflammation) and Sweet syndrome, respectively. | 26825166 |
| Inflammation, Cardiovascular Diseases | Altered Intercellular Communication | Association between diet-related inflammation, all-cause, all-cancer, and cardiovascular disease mortality, with special focus on prediabetics: findings from NHANES III. | 26825592 |
| Inflammation, Primary malignant neoplasm, Cardiovascular Diseases, Cyclophosphamide/Vincristine/Dacarbazine Regimen, Diabetes Mellitus | Altered Intercellular Communication | Chronic inflammation is associated with increased risk of cancer, cardiovascular disease (CVD), and diabetes. | 26825592 |
| Inflammation, Diabetic Ketoacidosis, Diabetes Mellitus | Altered Intercellular Communication | Diabetic ketoacidosis (DKA) is a life-threatening acute complication of diabetes mellitus and the novel systemic inflammation marker platelet-to-lymphocyte ratio (PLR) may be associated with clinical outcome in patients with DKA. | 26825908 |
| Inflammation, Atherosclerosis | Altered Intercellular Communication | Inflammation plays an important role in the pathogenesis of atherosclerosis. | 26825917 |
| Inflammation | Altered Intercellular Communication | Recent studies suggest that the neutrophil-lymphocyte ratio (NLR) as a marker of inflammation is associated with mortality in surgical patients. | 26825931 |
| Ulcerative Colitis | Altered Intercellular Communication | Cigarette smoke suppresses inflammation-induced apoptosis in intestinal epithelial cells (DLD-1), which may explain its protective effect in UC. | 26826017 |
| Inflammation, Liver Dysfunction, Heart Diseases, Systemic disease, Malignant Neoplasms | Altered Intercellular Communication | Patients with systemic diseases, including structural heart disease, hepatic or renal dysfunction, collagen disease, malignancy, and inflammation were excluded. | 26826137 |
| Inflammation | Altered Intercellular Communication | D-dimer is a manifestation of endogenous fibrinolytic activity and associated with inflammation process. | 26826394 |
| ARCN1 gene, Inflammation | Altered Intercellular Communication | D-dimer is increased in COPD patients, and could be considered as an inflammatory marker for the assessment of inflammation in the progression of COPD. | 26826394 |
| Inflammation, Liver Cirrhosis, FAM126A gene | Altered Intercellular Communication | HCV is suspected to induce HCC primarily through chronic inflammation and promotion of cirrhosis, a well-known pre-neoplastic condition. | 26827631 |
| Inflammation, Impaired cognition, Data types - Address, Nerve Degeneration | Altered Intercellular Communication | CSF YKL-40, a biomarker of glial inflammation, is associated with a cerebral structural signature distinct from that related to p-tau neurodegeneration at the earliest stages of cognitive decline due to AD. | 26827642 |
| Inflammation | Altered Intercellular Communication | Histological remission was defined as absence of active inflammation (Geboes score <3.1) and absence of basal plasmacytosis. | 26829408 |
| Inflammation, Hemolysis (biological function) | Altered Intercellular Communication | Multivariate logistic regression and receiver operating characteristics (ROC) analysis revealed a significant association between increased risk of breakthrough hemolysis and prolonged dosing intervals of 17 days or more and concomitant inflammation: odds ratios (OR) and 95% confidence intervals (CIs) were 1.6 (1.3-2.0, p<0.01) and 5.5 (1.3-22.8, p=0.02), respectively. | 26830487 |
| ARCN1 gene, Inflammation, Chronic Obstructive Airway Disease | Altered Intercellular Communication | Objective Although chronic obstructive pulmonary disease (COPD) is characterized by systemic inflammation, the association between the neutrophil to lymphocyte ratio (NLR; an indicator of inflammation) and the clinical status of COPD has not been well studied. | 26831014 |
| ARCN1 gene, Asthma, Airway structure | Altered Intercellular Communication | As patients with COPD and asthma already have a compromised respiratory function and chronic airway inflammation, they are expected to be at increased risk for adverse respiratory health effects. | 26831047 |
| Inflammation, Angiolymphoid hyperplasia, Lymphadenopathy | Altered Intercellular Communication | Multicentric Castleman's disease (MCD) is a pre-malignancy that presents with lymphadenopathy and features of systemic inflammation. | 26831502 |
| Ischemia, Inflammation | Altered Intercellular Communication | Magnetic resonance imaging showed diffusion restriction concerning for ischemia with areas of ring enhancement suggestive of inflammation. | 26831951 |
| fibroma, Inflammation, Granuloma | Altered Intercellular Communication | There was a significant correlation between mast cell count and the intensity of inflammation in the irritation fibroma and pyogenic granuloma groups. | 26832178 |
| Inflammation, Damage | Altered Intercellular Communication | Serum 14-3-3e protein is a joint-derived biomarker that up-regulates cytokines and enzymes that perpetuate local and systemic inflammation and may contribute to joint damage. | 26832367 |
| Inflammation, Psoriasis, Metabolic Syndrome X, Cardiovascular Abnormalities | Altered Intercellular Communication | The inexorable inflammation in patients of psoriasis predisposes to various disorders, notably, a cluster of cardiovascular and metabolic abnormalities christened 'metabolic syndrome'. | 26832843 |
| Granulomatous inflammation | Altered Intercellular Communication | Results showed a 2 mm-long whitish nematode spiralised in muscular layer of colon mucosa surrounded by granulomatous inflammation. | 26832924 |
| Dermatitis, Atopic, Inflammation | Altered Intercellular Communication | First-line treatments for atopic eczema focus on maintaining and repairing the skin barrier (emollients) and reducing inflammation (topical steroids); allergen and irritant avoidance are also important to achieve disease control. | 26833520 |
| Acute and chronic inflammation | Altered Intercellular Communication | The patients with chronic sinonasal inflammation were treated with fluticasone nasal spray for 14 days. | 26833624 |
| Communicable Diseases, Helicobacter pylori, Inflammation | Altered Intercellular Communication | Its development is closely linked to an infection with Helicobacter pylori and chronic, cytokine-driven inflammation. | 26835712 |
| Inflammation, Data types - Address | Altered Intercellular Communication | Inflammation interacted with AD pathology, such that greater MCP-1 and lower Ab42 was associated with altered microstructure in bilateral frontal and right temporal lobe and that greater MCP-1 and greater P-Tau181 was associated with altered microstructure in precuneus. | 26836182 |
| Inflammation, Damage, Data types - Address | Altered Intercellular Communication | Inflammation may play a role in neural damage in preclinical AD. | 26836182 |
| Airway structure | Altered Intercellular Communication | Antiviral type I IFN production is impaired in those with neutrophilic airway inflammation and in those prescribed high doses of inhaled corticosteroids. | 26836898 |
| allergic inflammation | Altered Intercellular Communication | SP-D also regulates allergic inflammation and promotes the removal of apoptotic cells. | 26836907 |
| Inflammation, Inflammatory disorder | Altered Intercellular Communication | However, associating inflammatory diseases with specific microbial members of the microbiota is challenging, because clinically detectable inflammation and its treatment can alter the microbiota's composition. | 26837003 |
| Inflammation, Chronic disease | Altered Intercellular Communication | Because low-grade inflammation may precede chronic diseases, following an overall healthy lifestyle may help lower risk of these diseases. | 26838054 |
| Inflammation, Atrial Fibrillation by ECG Finding | Altered Intercellular Communication | Biomarkers of inflammation and risk of cardiovascular events in anticoagulated patients with atrial fibrillation. | 26839066 |
| Atrial Fibrillation, Inflammation, Atrial Fibrillation by ECG Finding, Cerebrovascular accident | Altered Intercellular Communication | Atrial fibrillation (AF) is a risk factor for stroke and mortality and the prothrombotic state has been linked to inflammation. | 26839066 |
| Inflammation, Fibrous, Necrosis | Altered Intercellular Communication | Symptomatic patients had a larger volume of embolic debris, mean particle size, and the biomarkers associated with inflammation, necrotic core, and diminished fibrous cap. | 26839124 |
| Inflammation, Primary malignant neoplasm | Altered Intercellular Communication | The IL6/STAT3 axis promotes inflammation, angiogenesis, and cancer. | 26839145 |
| Inflammation, Atrial Fibrillation by ECG Finding, Coronary Artery Disease, Endothelial dysfunction, Atrial Fibrillation | Altered Intercellular Communication | Atrial fibrillation (AF) can be associated with an increased risk of developing coronary artery disease (CAD) due to mechanisms of inflammation, endothelial dysfunction and adverse atrial remodelling. | 26839165 |
| Creutzfeldt-Jakob disease | Altered Intercellular Communication | By contrast, human growth hormone-associated cases of iatrogenic CJD (iCJD) in the United Kingdom (UK) are associated with exposure to an exogenous source of PrP(Sc). | 26840342 |
| Inflammation, Chronic Kidney Insufficiency, Atrial Fibrillation, Chronic Kidney Diseases | Altered Intercellular Communication | In this study, we examined the association between inflammation and AF in 3,762 adults with CKD, enrolled in the Chronic Renal Insufficiency Cohort (CRIC) study. | 26840403 |
| Anemia of chronic disease, Anemia, Chronic disease | Altered Intercellular Communication | Its cause is multifactorial and mostly associated with absolute iron deficiency (iron deficiency anemia) and/or functional iron deficiency (inflammation anemia or anemia of chronic disease). | 26840464 |
| Intestinal metaplasia, Inflammation | Altered Intercellular Communication | A significant association was observed between s1m1cagA+ strains and a higher degree of inflammation, neutrophil activity and development of intestinal metaplasia. | 26840466 |
| Vasculitis, Communicable Diseases | Altered Intercellular Communication | We stress usefulness of this method in large vessel inflammation and infection. | 26841377 |
| vascular inflammations, Infection | Altered Intercellular Communication | The literature exploration was focusing on vascular inflammation and infections and 18-FDG PET. | 26841377 |
| Inflammation, Atherosclerosis, Plaque, Atherosclerotic | Altered Intercellular Communication | From this work inflammation associated with atheromatic process and vulnerable atherosclerotic plaque we excluded. | 26841377 |
| Inflammation, Infection | Altered Intercellular Communication | 18F-FGD PET/CT is a sensitive metabolic, reliable, non-invasive imaging modality suitable for diagnosis and follow-up of inflammation and infections in vascular system. | 26841377 |
| Inflammation | Altered Intercellular Communication | Toll-like receptors (TLRs) are important mediators of adipose tissue inflammation and they are able to recognize endogenous products released by damaged cells. | 26841679 |
| Inflammation, Hypertrophy | Altered Intercellular Communication | Our findings suggested that EAT hypertrophy in CAD promotes adipocyte degeneration and drives local inflammation through increased infiltration of macrophages which are mainly polarized towards an M1 state and express both TLR-2 and TLR-4. | 26841679 |
| Clinical Events Domain, Menstrual epilepsy, Epilepsy | Altered Intercellular Communication | Catamenial epilepsy (CE) is a commonly observed phenomenon among women with epilepsy, the management of which is both hormonal and non-hormonal. | 26841950 |
| Necrotizing granulomatous inflammation, Tuberculosis | Altered Intercellular Communication | A mediastinoscopy was diagnostic as histology revealed necrotizing granulomatous inflammation and the presence of acid-fast bacilli, indicating mediastinal tuberculosis. | 26842759 |
| Chlamydia trachomatis, Conjunctivitis | Altered Intercellular Communication | Inverse relationship between microRNA-155 and -184 expression with increasing conjunctival inflammation during ocular Chlamydia trachomatis infection. | 26842862 |
| Inflammation | Altered Intercellular Communication | Alternative p38 mitogen-activated kinases (p38g and p38d) have been shown to contribute to inflammation in different diseases. | 26843485 |
| Inflammation, Fatty degeneration, Neutrophil Infiltration | Altered Intercellular Communication | We further show that neutrophil infiltration in wild-type mice contributes to steatosis development by means of inflammation and liver metabolic changes. | 26843485 |
| Refractory anemias, Rheumatoid Arthritis, Arthritis | Altered Intercellular Communication | Rheumatoid arthritis (RA) is characterized by chronic joint inflammation and associates with HLA-DRB1*04. | 26844284 |
| Edema Limbs, CTCAE 5, Inflammation, Fever, CTCAE, Shock, Calusterone, Capillary Leak Syndrome | Altered Intercellular Communication | Because fever and raised inflammation parameters are not observed in idiopathic capillary leak syndrome (SCLS; Clarkson disease), a diagnosis of SCL-like syndrome was made.Albumin solution, high-dose methylprednisolone and intravenous immunoglobulins (IVIG) infusion were administered with a rapid improvement of her clinical condition.The prompt treatment with steroids and IVIG likely prevented the life-threatening shock syndrome that can occur in SCLS, with acute hypotensive attacks, and severe limbs edema requiring fasciotomy.All clinical and laboratory findings supported autoinflammation as the underlying pathogenic mechanism of the syndrome. | 26844485 |
| Inflammatory Bowel Diseases, Inflammation | Altered Intercellular Communication | Characterization of preclinical systemic inflammation could contribute to the understanding of the biology of IBD and, ultimately, facilitate development of strategies for early disease detection and intervention. | 26844874 |
| Inflammatory Bowel Diseases, Inflammation | Altered Intercellular Communication | Subclinical levels of systemic inflammation may be a feature of an early disease state that precedes the development of symptomatic IBD. | 26844874 |
| Airway structure, Allergic asthma | Altered Intercellular Communication | Inhaled allergen increases DCs in bone marrow and trafficking of DCs into the airway, which is associated with the development airway inflammation in subjects with allergic asthma. | 26844926 |
| Inflammatory abnormality of the eye, Cornea | Altered Intercellular Communication | Based on previous studies, RGTA seems to be a promising therapeutic agent for controlling ocular surface inflammation and promoting corneal healing. | 26845313 |
| Upper Respiratory Infections | Altered Intercellular Communication | Asthma is a heterogeneous multifactorial disease that is characterized in most cases by chronic respiratory tract inflammation. | 26845862 |
| Cataract, Inflammation, Uveitis | Altered Intercellular Communication | Absolute and long-lasting control of ocular, and possibly systemic, inflammation predisposes uveitis patients to satisfactory results after cataract extraction and intraocular lens implantation. | 26846356 |
| Granulomatosis, Autoimmune Diseases, Vasculitis of large artery, Necrotizing granulomatous inflammation, Systemic Vasculitis | Altered Intercellular Communication | Granulomatosis with polyangiitis (GPA) is a rare autoimmune disease characterized by necrotizing granulomatous inflammation and small vessel vasculitis that primarily involves the upper airways, lungs, and kidneys. | 26847102 |
| vascular inflammations | Altered Intercellular Communication | In 3 of the 12 patients occult areas of vascular inflammation were identified that were not previously appreciated on usual organ screening in GPA. | 26847102 |
| Inflammation, Chronic disease | Altered Intercellular Communication | Thus, in Molina risk factors typical of both under-developed and developed countries coexist, generating a unique profile associated with inflammation, oxidative stress and chronic diseases. | 26847446 |
| Diabetes Mellitus | Altered Intercellular Communication | Older Age, Higher Body Mass Index and Inflammation Increase the Risk for New-Onset Diabetes and Impaired Glucose Tolerance in Patients on Peritoneal Dialysis. | 26847585 |
| palladium, Inflammation, Diabetes Mellitus | Altered Intercellular Communication | Traditional and uremic-related risk factors, such as older age, higher BMI, and inflammation, contribute to new-onset diabetes and impaired glucose tolerance in PD patients. | 26847585 |
| Schizophrenia | Altered Intercellular Communication | g-aminobutyric acid (GABA), the major inhibitory neurotransmitter in adult mammalian brain, plays a major role in normal brain development, and has been strongly implicated in the pathobiology of schizophrenia. | 26848839 |
| Inflammation, Fibrosis Assessment | Altered Intercellular Communication | Pretreatment and follow up biopsies were scored for inflammation, fibrosis, bile ductal injury and ductular reaction. | 26849025 |
| Data types - Address, Inflammatory disorder | Altered Intercellular Communication | Sphingolipids are widely known to have roles in the pathogenesis of inflammatory diseases, where the precise roles for sphingolipids in inflammation-associated pathogenesis of AD are not well understood. | 26849355 |
| Inflammation, Data types - Address | Altered Intercellular Communication | The results of our analysis suggest the following two prospects about inflammation in AD: (1) ceramide could play important roles in both inflammatory and anti-inflammatory pathways of AD, and (2) several factors such as Sphingomyelinase and Siglec-11 may be associated with ceramide related inflammation and anti-inflammation pathways in AD. | 26849355 |
| Nasal Polyps | Altered Intercellular Communication | Age-Related Decline of Neutrophilic Inflammation Is Associated with Better Postoperative Prognosis in Non-eosinophilic Nasal Polyps. | 26849431 |
| Dermatomyositis, Polymyositis, Myositis | Altered Intercellular Communication | Background Dermatomyositis and polymyositis (DM/PM) are inflammatory myopathies characterized by muscle inflammation/weakness. | 26850074 |
| Cerebral Amyloid Angiopathy, Inflammation | Altered Intercellular Communication | Pseudotumoral presentation of cerebral amyloid angiopathy-related inflammation. | 26850981 |
| Cerebral Amyloid Angiopathy, Inflammation | Altered Intercellular Communication | To identify the clinical and radiologic features that should raise suspicion for the pseudotumoral presentation of cerebral amyloid angiopathy-related inflammation (CAA-I). | 26850981 |
| Mycosis Fungoides, Inflammation, Lymphoma, T-Cell, Cutaneous | Altered Intercellular Communication | Sustained inflammation is a key feature of mycosis fungoides (MF), the most common form of cutaneous T-cell lymphoma (CTCL). | 26851186 |
| Stiff-Person Syndrome, Autoimmune Diseases of the Nervous System, SMS gene | Altered Intercellular Communication | Stiff person syndrome (SPS) is a rare autoimmune neurological disorder with antibodies against antigens involved in neurotransmission of gamma-aminobutyric acid (GABA). | 26851693 |
| Inflammation, Asthma | Altered Intercellular Communication | Our data underline a disconnect between clinical features and underlying inflammation, suggest IL-5 production is relatively steroid insensitive, and highlight the expression of YKL-40 in patients with neutrophilic inflammation and the expression of MMPs in patients with severe asthma. | 26851968 |
| Inflammation, Perforation of nasal septum | Altered Intercellular Communication | This indicates that presence of different strains of S. aureus can maintain a chronic inflammation in symptomatic nasal septal perforations. | 26852671 |
| Allergic asthma, Inflammation, Kit Ligand, human | Altered Intercellular Communication | These findings suggest that both SCF and IL-31 play an important role in mediating inflammation and enhancing severity of atopic asthma. | 26853551 |
| Inflammation, Liver damage | Altered Intercellular Communication | In the course of the UVB phototherapy, spongiosis and pleomorphy as parameters of inflammation and cellular damage did not show significant changes. | 26853735 |
| Inflammatory Bowel Diseases, Inflammation | Altered Intercellular Communication | Electrolyte abnormalities, chronic inflammation, and medication use (such as Infliximab) that are associated with IBD are all independent risk factors for QT interval prolongation. | 26853794 |
| Crohn Disease, Gastrointestinal inflammation, Ulcerative Colitis | Altered Intercellular Communication | Fecal calprotectin (FC) and myeloperoxidase (MPO) indicate intestinal inflammation in ulcerative colitis (UC) and Crohn's disease (CD). | 26854205 |
| Inflammation, Primary malignant neoplasm | Altered Intercellular Communication | Increasing evidence supports an association between systemic inflammation and cancer development and progression. | 26854438 |
| Inflammation, Neoplasms | Altered Intercellular Communication | The neutrophil to lymphocyte ratio (NLR) is used as a basic parameter of systemic inflammation in some tumors. | 26854438 |
| Inflammatory abnormality of the eye | Altered Intercellular Communication | Severe Ocular Inflammation Following Ranibizumab or Aflibercept Injections for Age-Related Macular Degeneration: A Retrospective Claims Database Analysis. | 26855278 |
| Ocular Motility Disorders, Inflammatory abnormality of the eye | Altered Intercellular Communication | Intravitreal injections of anti-vascular endothelial growth factor (VEGF) agents including ranibizumab and aflibercept are used to treat patients with ocular disorders such as neovascular age-related macular degeneration (nAMD); however, the injections are associated with rare instances of severe ocular inflammation. | 26855278 |
| Inflammatory abnormality of the eye | Altered Intercellular Communication | This study compared severe ocular inflammation rates in patients treated with ranibizumab versus aflibercept. | 26855278 |
| Inflammatory abnormality of the eye | Altered Intercellular Communication | The primary analysis compared severe ocular inflammation event rates per 1000 injections. | 26855278 |
| Inflammatory abnormality of the eye | Altered Intercellular Communication | No significant change occurred in the rate of severe ocular inflammation claims over time following ranibizumab treatment. | 26855278 |
| Inflammation, Complete atrioventricular block, Disease remission | Altered Intercellular Communication | TGF-b signalling is activated in CHB patients with active disease, while SMAD7 is up-regulated during the resolution of inflammation after successful treatment. | 26856334 |
| Inflammation | Altered Intercellular Communication | AIH-induced spinal plasticity is inhibited by systemic inflammation in animal models. | 26856344 |
| Inflammation, Stanford Cancer Institute, Insemination, Artificial, Homologous | Altered Intercellular Communication | Since SCI is frequently associated with systemic inflammation in humans, we tested the hypothesis that pretreatment with the anti-inflammatory agent ibuprofen enhances the effects of AIH. | 26856344 |
| Inflammation, Acute Coronary Syndrome | Altered Intercellular Communication | Red cell distribution width (RDW) and mean platelet volume (MPV) are novel markers of inflammation and oxidative stress and were associated with poor clinical outcomes in acute coronary syndrome. | 26857117 |
| Inflammation, Overweight, Metabolic Syndrome X | Altered Intercellular Communication | Overweight and obese individuals have an increased risk of developing the metabolic syndrome because of subsequent chronic inflammation and oxidative stress, which the antioxidant nutrient lycopene can reduce. | 26857614 |
| Inflammation, Fibrosis Assessment | Altered Intercellular Communication | Peritoneal inflammation and fibrosis in C-reactive protein transgenic mice undergoing peritoneal dialysis solution treatment. | 26857687 |
| palladium, Inflammation, Fibrosis Assessment | Altered Intercellular Communication | Peritoneal dialysis (PD) is known to cause peritoneal inflammation and fibrosis. | 26857687 |
| palladium, Inflammation, Fibrosis Assessment | Altered Intercellular Communication | We compare the degree of peritoneal inflammation and fibrosis in wild-type (WT) and CRP-transgenic (Tg) mice after PD treatment. | 26857687 |
| Inflammation, Fibrosis Assessment | Altered Intercellular Communication | Parietal peritoneal and omental tissues were collected for the assessment of inflammation and fibrosis. | 26857687 |
| palladium, Inflammation, Fibrosis Assessment | Altered Intercellular Communication | CRP-Tg mice have significantly more inflammation and fibrosis than WT mice after PD treatment. | 26857687 |
| palladium, Inflammation, Fibrosis Assessment | Altered Intercellular Communication | Our results suggest that CRP play a role in inflammation and fibrosis induced by PD. | 26857687 |
| Inflammation, Primary malignant neoplasm | Altered Intercellular Communication | Inflammation is associated with cancer but there are conflicting reports on associations of biomarkers of inflammation with cancer risk and mortality. | 26860264 |
| Inflammation, Primary malignant neoplasm | Altered Intercellular Communication | Our study suggests that inflammation is associated with cancer risk and mortality, and combining inflammatory biomarkers into a score is a robust method of elucidating this association. | 26860264 |
| Intraocular inflammation, Disease, Uveitis | Altered Intercellular Communication | The uveitis masquerade syndromes (UMS) are a group of ocular diseases that may mimic chronic intraocular inflammation. | 26860883 |
| Acute and chronic inflammation | Altered Intercellular Communication | High-Potency Topical Steroids: An Effective Therapy for Chronic Scalp Inflammation in Rapp-Hodgkin Ectodermal Dysplasia. | 26861896 |
| Inflammation, Orf virus | Altered Intercellular Communication | We also note marked similarities between this scalp inflammation and "erosive pustular dermatosis of the scalp," a condition more typically found in elderly individuals with severe scalp sun damage, and speculate about possible shared pathogenetic mechanisms. | 26861896 |
| Airway structure, Inflammatory Bowel Diseases, Intestinal Diseases | Altered Intercellular Communication | FeNO level, a marker of airway inflammation, is elevated in children with inflammatory bowel diseases irrespective of their intestinal disease activity. | 26862933 |
| Prostate carcinoma, prostatitis | Altered Intercellular Communication | Serum Autoantibodies in Chronic Prostate Inflammation in Prostate Cancer Patients. | 26863016 |
| Inflammation, Non-Malignant | Altered Intercellular Communication | Chronic inflammation is frequently observed on histological analysis of malignant and non-malignant prostate specimens. | 26863016 |
| Prostate carcinoma, prostatitis | Altered Intercellular Communication | We aimed to identify and validate prostate inflammation associated serum autoantibodies in prostate cancer patients and evaluate the expression of corresponding autoantigens. | 26863016 |
| Inflammation, Prostate carcinoma | Altered Intercellular Communication | Radical prostatectomy specimens of prostate cancer patients (N = 70) were classified into high and low inflammation groups according to the amount of tissue infiltrating lymphocytes. | 26863016 |
| Prostatic Neoplasms | Altered Intercellular Communication | All three autoantigens were differentially expressed in primary and/or castration resistant prostate tumors when analyzed in an inflammation-independent tissue microarray. | 26863016 |
| prostatitis | Altered Intercellular Communication | This supports evaluation of autoantibodies as non-invasive markers for prostate inflammation. | 26863016 |
| Cessation of life, Inflammation | Altered Intercellular Communication | The long-term consequences of increased inflammation in DBD and increased cell death in DCD allografts are unknown and warrant further investigation. | 26863224 |
| Inflammatory abnormality of the eye, Stevens-Johnson Syndrome, CTCAE | Altered Intercellular Communication | A 61-year-old man developed bilateral symblephara and severe ocular surface inflammation from Stevens-Johnson syndrome/TEN secondary to allopurinol. | 26863497 |
| Ventricular Arrhythmia, CTCAE 5.0, Coronary Artery Disease, Metabolic Syndrome X | Altered Intercellular Communication | Inflammation markers are associated with metabolic syndrome and ventricular arrhythmia in patients with coronary artery disease. | 26864064 |
| Inflammation, Coronary Artery Disease, Atherosclerosis | Altered Intercellular Communication | Inflammation plays a major role in the development and progression of atherosclerosis and coronary artery disease (CAD). | 26864064 |
| Ventricular Arrhythmia, CTCAE 5.0, Inflammation | Altered Intercellular Communication | Their strong association with life-threatening ventricular arrhythmia emphasizes the proarrhythmic role of inflammation in the increased cardiovascular risk of CAD patients. | 26864064 |
| Crohn Disease, Opportunistic Infections | Altered Intercellular Communication | Since his paradoxical inflammations were not severe and opportunistic infections were excluded, IFX was cautiously continued for refractory Crohn's disease. | 26864464 |
| Inflammation, Blood Vessel | Altered Intercellular Communication | The coexistence of increased obesity-related subclinical inflammation and decreased antioxidant capacity can be observed even in prepubescence, and may eventually increase the risk of long-term vascular damage. | 26865084 |
| Inflammation, Tissue Congestion, Chronic heart failure, Anorexia, Ventricular Dysfunction, Cachexia | Altered Intercellular Communication | Intestinal congestion and right ventricular dysfunction: a link with appetite loss, inflammation, and cachexia in chronic heart failure. | 26865478 |
| Inflammation, Cachexia | Altered Intercellular Communication | Logistic regression analysis showed that BWT was associated with cachexia, even after adjusting for cardiac function, inflammation, and stages of HF (odds ratio 1.4, 95% CI: 1.0-1.8; P-value = 0.03). | 26865478 |
| Dermatitis, Atopic, Pruritus, Inflammation, physiopathological | Altered Intercellular Communication | Atopic dermatitis is a common pruritic skin disease in which barrier dysfunction and cutaneous inflammation contribute to pathogenesis. | 26865566 |
| Sialadenitis, Fibrosis Assessment | Altered Intercellular Communication | This dysfunction was associated with more pronounced labial salivary glandular inflammation but not fibrosis. | 26867144 |
| Inflammation, HIV Infections, Atherosclerosis, Cardiovascular Diseases, Cyclophosphamide/Vincristine/Dacarbazine Regimen | Altered Intercellular Communication | Persistent inflammation and immune activation has been hypothesized to contribute to increased prevalence of subclinical atherosclerosis and cardiovascular disease (CVD) risk in patients with chronic HIV infection. | 26867220 |
| Pain Distress Question, No ocular symptoms, Inflammatory abnormality of the eye, Lacrimation, Pruritus | Altered Intercellular Communication | The initial ocular symptoms prior to the use of TEM were mainly those of ocular surface inflammation: tearing (77.4%), redness (74.9%), itchiness (71.6%) and pain (70.3%). | 26867254 |
| Interstitial inflammation | Altered Intercellular Communication | A renal biopsy was performed and the pathology revealed viral cytopathic changes in the tubular epithelium with interstitial inflammation. | 26867385 |
| Vasculitis, Cyclophosphamide/Vincristine/Dacarbazine Regimen, Chronic disease | Altered Intercellular Communication | According to previous studies, sulodexide suppresses intravascular inflammation when used in patients with chronic venous disease (CVD). | 26868135 |
| APP gene, Inflammation, Asthma, Aortic Aneurysm, Abdominal | Altered Intercellular Communication | Both asthma and abdominal aortic aneurysms (AAA) involve inflammation. | 26868210 |
| Inflammation | Altered Intercellular Communication | Surgical intervention should be performed in a quiescent period of disease if possible given that biological inflammation at the time of intervention increases the complication rate. | 26870600 |
| Pneumonitis | Altered Intercellular Communication | Delayed clearance of the bacteria and stronger lung inflammation observed in infected CS-exposed mice were associated with an altered production of IL-17 and IL-22 by innate immune cells. | 26870795 |
| Microalbuminuria, Inflammation | Altered Intercellular Communication | Exposure to PM, VOCs and PAHs in indoor air and presence of urinary PAHs metabolites may lead to inflammation, which can cause microalbuminuria in kitchen workers, as observed in the present study. | 26871707 |
| Arterial Stiffness, HD Term Type, Inflammation | Altered Intercellular Communication | In HD, inflammation is one of the major causes of increased arterial stiffness. | 26871812 |
| Inflammation, peripheral blood | Altered Intercellular Communication | We analyzed clinical test data pertaining to peripheral blood T cells, antibodies, inflammation markers, and cerebral spinal fluid (CSF) completed during the disease onset phase and 5 years following diagnosis. | 26871820 |
| Intestinal metaplasia, Inflammation, Atrophic | Altered Intercellular Communication | Scores for chronic inflammation and activity declined significantly (P<0.001) 3 months after treatment, whereas those for atrophy and intestinal metaplasia showed no significant change. | 26871968 |
| Hyperlipidemia, Disorder of soft tissue, Diabetes Mellitus, Icterus, Acute Coronary Syndrome, Hepatobiliary Disorder, Traumatic injury, Malignant Neoplasms, Acute and chronic inflammation, Kidney Failure | Altered Intercellular Communication | Patients with any condition (diabetes, icterus, hyperlipidemia, physical, or surgical trauma, acute coronary syndrome, pregnancy, renal insufficiency, liver disease, malignancy, collagen tissue disease, chronic or acute inflammation, drug use affecting thrombocyte function) that could affect plasma VWF antigen or ADAMTS-13 levels were excluded. | 26872106 |
| Inflammation, Acute inflammation | Altered Intercellular Communication | A high-fat meal (HFM) induces an increase in blood lipids (postprandial lipemia; PPL), systemic inflammation, and acute airway inflammation. | 26872295 |
| Airway structure, Inflammation | Altered Intercellular Communication | Our purpose was to determine the effects of an acute bout of exercise on airway inflammation post-HFM and to identify whether any protective effect of exercise on airway inflammation was associated with a reduction in PPL or systemic inflammation. | 26872295 |
| Airway structure, Lipemia - observation | Altered Intercellular Communication | In summary, an acute bout of moderate-intensity exercise performed 12 h prior to an HFM did not change postprandial airway inflammation or lipemia in healthy, 18- to 29-year-old men. | 26872295 |
| Inflammation, Chronic disease | Altered Intercellular Communication | Both self-rated health (SRH) and inflammation are implicated in chronic diseases and premature mortality. | 26872420 |
| Uterine Fibroids | Altered Intercellular Communication | Traditional management with high-dose hormonal regimens may not be as effective when used in women with fibroids. | 26872761 |
| Inflammation, Pancreatic carcinoma | Altered Intercellular Communication | Basophil Recruitment into Tumor-Draining Lymph Nodes Correlates with Th2 Inflammation and Reduced Survival in Pancreatic Cancer Patients. | 26873846 |
| Inflammation, Neoplasms, Pancreatic carcinoma | Altered Intercellular Communication | Our results show how basophils recruited and activated in TDLNs under the influence of the tumor microenvironment regulate tumor-promoting Th2 inflammation in PDAC, helping in illuminating a key element of the immune milieu of pancreatic cancer. | 26873846 |
| Peripheral Vascular Diseases, Inflammation, Chronic Kidney Diseases | Altered Intercellular Communication | A low body-mass index, peripheral arterial disease, chronic kidney disease and inflammation were predictive for 3-year all-cause mortality. | 26874209 |
| Inflammation, Disease remission, Ulcerative Colitis | Altered Intercellular Communication | We evaluated the performance of blood and faecal biomarkers for differentiating between endoscopic inflammation and mucosal healing, and clinically active disease and sustained clinical remission, and determined the predictive value for a flare in patients with ulcerative colitis [UC]. | 26874351 |
| Inflammation, Disease remission | Altered Intercellular Communication | Median levels for active disease confirmed by EI [n = 35] vs clinical remission with endoscopic inflammation [n = 37] vs mucosal healing [n = 107] for FLA were 44/37/4 ug/g, CAL 25/20/10 ug/g [both p < 0.0001], PMN-e 0.06/0.03/0.02 ug/g, CRP 0.7/0.2/0.2mg/dl [both p < 0.001], and WBC 7.0/6.5/6.4/nl [p = 0.1]. | 26874351 |
| Histiocytes, Inflammation, Arteritis | Altered Intercellular Communication | T-lymphocytic inflammation with little neutrophil and histiocyte infiltration may be a pathological feature of necrotizing arteritis observed in pulmonary sequestration. | 26874730 |
| Inflammation, Impaired cognition | Altered Intercellular Communication | Dietary pattern, inflammation and cognitive decline: The Whitehall II prospective cohort study. | 26874911 |
| Inflammation, Impaired cognition | Altered Intercellular Communication | Low-grade inflammation appears to play an etiological role in cognitive decline. | 26874911 |
| Inflammation, Impaired cognition | Altered Intercellular Communication | We aimed to investigate dietary patterns associated with inflammation and whether such diet is associated with cognitive decline. | 26874911 |
| Steatohepatitis, Injury of liver, Inflammation | Altered Intercellular Communication | This, however, was more pronounced upon long-term ALA intake, leading to hepatic steatosis and liver injury, as indicated by increased inflammation and disruption of the general hepatic architecture. | 26876280 |
| Inflammation, Plaque, Atherosclerotic, Atherosclerosis | Altered Intercellular Communication | The presence of bacteria and other microorganisms in atherosclerotic plaque has long been known, however, the cause of chronic inflammation and the role of bacteria/viruses in atherosclerosis have not been studied in detail. | 26878370 |
| Inflammation, atherosclerotic | Altered Intercellular Communication | The objective of this study was to clarify the cause of the chronic inflammation within atherosclerotic plaques, and determine if any bacteria and/or viruses are involved in the inflammatory pathway. | 26878370 |
| Inflammation, Plaque, Atherosclerotic, Atherosclerosis | Altered Intercellular Communication | While the presence of bacterial biofilm structures in atherosclerotic plaque does not prove that biofilm is the proximate cause of atherosclerosis, it could contribute to the persistent inflammation associated with it. | 26878370 |
| Neuronal degeneration, Inflammation, palladium, Nerve Degeneration | Altered Intercellular Communication | CSF biomarkers reflecting Lewy body pathology and neurodegeneration (a-synuclein), neuronal degeneration (tau, phosphorylated tau, and neurofilament light), and inflammation (YKL-40) increase significantly over 2 years in PD. | 26878815 |
| Autoimmune Diseases, Inflammation, Juvenile Myelomonocytic Leukemia | Altered Intercellular Communication | Chronic inflammation and autoimmunity as risk factors for the development of chronic myelomonocytic leukemia? | 26879691 |
| Autoimmune Diseases, Inflammation, Juvenile Myelomonocytic Leukemia, Leukemia, Myelomonocytic, Chronic | Altered Intercellular Communication | In this study, we investigate if chronic inflammation and autoimmunity might be related to the development of chronic myelomonocytic leukemia (CMML). | 26879691 |
| Autoimmune Diseases, Inflammation | Altered Intercellular Communication | Subjects with a history of chronic inflammation or autoimmune disorders were retrieved and odds ratios (ORs) calculated. | 26879691 |
| Sepsis, Inflammation, Communicable Diseases | Altered Intercellular Communication | Sepsis induces inflammation in response to infection and is a major cause of mortality and hospitalization in children. | 26880005 |
| Inflammation, Obesity | Altered Intercellular Communication | Obesity induces chronic inflammation leading to many clinical manifestations. | 26880005 |
| Inflammation, Metabolic Syndrome X, Capsulitis | Altered Intercellular Communication | Adhesive capsulitis: An age related symptom of metabolic syndrome and chronic low-grade inflammation? | 26880627 |
| Inflammation, Primary malignant neoplasm, Pain Distress Question, Demographics Domain, Nervous System Physiological Phenomena, Metabolic Syndrome X, Cardiovascular Diseases, Cyclophosphamide/Vincristine/Dacarbazine Regimen, Diabetes Mellitus, Obesity | Altered Intercellular Communication | Obesity and metabolic syndrome, which are strongly associated with chronic low grade inflammation, are becoming increasingly understood to underlie a raft of morbid states including upper limb pain syndromes, diabetes (DM), cardiovascular disease (CVD), cancer and central nervous system dysfunction and degeneration. | 26880627 |
| Inflammation, Demographics Domain, Metabolic Syndrome X, Fibrosis Assessment, Cyclophosphamide/Vincristine/Dacarbazine Regimen | Altered Intercellular Communication | The hypothesis argues that similar to DM and CVD, the inflammation and capsular fibrosis seen in AC is precipitated by metabolic syndrome and chronic low grade inflammation. | 26880627 |
| Inflammation, polyps, Cutaneous Precancerous Condition, "Reinkes edema", Cyst, Leukoplakia | Altered Intercellular Communication | The fifty-two tissue specimens, including 10 samples of cancerous lesion, 10 adjacent normal tissue, 10 chronic inflammation, eight cyst, three leukoplakia, four polyp, and seven Reinke's edema, were obtained during laryngological procedures. | 26881757 |
| Inflammation | Altered Intercellular Communication | Our results reveal that more severe inflammation, based on high levels of IL-6, is associated with lower expression of VPAC1 (p<0.001) and conversely with increased expression of VPAC2 (p<0.001). | 26881970 |
| Inflammation | Altered Intercellular Communication | Patients with more severe inflammation and higher disease activity show lower levels of VPAC1 expression, which is associated with patient-reported impairment. | 26881970 |
| Inflammatory disease of mucous membrane | Altered Intercellular Communication | Of the 33 children, 28 (85%) had gut mucosal inflammation, mostly affecting the colon (80%). | 26882369 |
| Eosinophilic inflammation | Altered Intercellular Communication | There was a negative association with the use of immunomodulators and the presence of eosinophil inflammation. | 26882369 |
| Juvenile arthritis, Inflammation, Colitis | Altered Intercellular Communication | The majority of children with JIA and GI symptoms have histological evidence of mild nonspecific inflammation, but some having active colitis and prominent eosinophil infiltrate. | 26882369 |
| Cessation of life, Inflammation, Brain Injuries | Altered Intercellular Communication | Dysregulated inflammation post-TBI exacerbates secondary brain injury and contributes to unfavorable patient outcomes including death. | 26883121 |
| Multimorbidity, Inflammation, Chronic disease | Altered Intercellular Communication | Multimorbidity is the co-occurrence of chronic diseases associated with low-grade chronic inflammation of connective tissue. | 26883337 |
| Multimorbidity | Altered Intercellular Communication | The alterations in plasma FN molecular status were associated with micro-inflammation and micro-coagulation, as well as multimorbidity of subjects and their physiological aging. | 26883337 |
| Eosinophilic Granuloma, Systemic Vasculitis | Altered Intercellular Communication | Asthma Control and Airway Inflammation in Patients with Eosinophilic Granulomatosis with Polyangiitis. | 26883543 |
| Airway structure, Rhinosinusitis, Asthma | Altered Intercellular Communication | Although low systemic disease activity was documented in the large majority of patients, poorly controlled asthma and rhinosinusitis with eosinophilic airway inflammation were demonstrated in almost all patients. | 26883543 |
| Inflammation, Mycoses, oral fungal infection | Altered Intercellular Communication | Since fungal oral infections have not yet been studied in this respect, the aim of our study is to determine whether the local inflammation caused by oral fungal infection of the palatal tissue (denture stomatitis-DS) is associated with the systemic inflammatory response. | 26883670 |
| Inflammation, Diabetes Mellitus, Non-Insulin-Dependent | Altered Intercellular Communication | Chronic low-grade inflammation contributes to the pathology and complications of type 2 diabetes (T2D). | 26883847 |
| Inflammation, Diabetes Mellitus, Non-Insulin-Dependent | Altered Intercellular Communication | We examined the ability of IL10 to inhibit inflammation in human T2D immune cells and explored underlying mechanisms using macrophage models. | 26883847 |
| Inflammation, Diabetes Mellitus, Non-Insulin-Dependent | Altered Intercellular Communication | This data supports the idea that IL10 hyporesponsiveness may contribute to chronic inflammation in T2D. | 26883847 |
| Inflammation, Diabetes Mellitus, Non-Insulin-Dependent | Altered Intercellular Communication | These novel findings suggest that strategies aimed to overcome IL10 hyporesponsiveness may hold therapeutic potential for reducing inflammation in T2D. | 26883847 |
| Acute Kidney Injury, CTCAE, Inflammation, Kidney Failure, Acute | Altered Intercellular Communication | Systemic inflammation is involved in the development of acute kidney injury (AKI) after cardiac surgery with cardiopulmonary bypass (CPB). | 26884251 |
| Inflammation, Specimen Type - Fistula, Cellulitis | Altered Intercellular Communication | Dermoid cyts are often innocent, however complications such as inflammation of the fistula or preseptal cellulitis are occasionally seen. | 26885559 |
| Inflammation | Altered Intercellular Communication | Considering the important roles that SIRT6 plays in the cardiovascular system, inflammation, and lipid and cholesterol metabolism, genetic variants were hypothesized to contribute to MI development. | 26886147 |
| Blindness, Inflammation | Altered Intercellular Communication | Although not individually significant, transmural inflammation (p=0.11), luminal thrombus (p=0.17) and giant cells (p=0.20) were more frequent in patients who suffered blindness, whereas fragmentation of the internal elastic lamina (p=0.04), and intimal thickening (p=0.02) were more frequent in patients without blindness. | 26886472 |
| Inflammation | Altered Intercellular Communication | The presence of giant cells was associated with transmural inflammation (p=0.06), jaw claudication (p=0.02), and higher inflammatory markers. | 26886472 |
| Aggressive course, Inflammation | Altered Intercellular Communication | Giant cells are strongly associated with jaw claudication and systemic markers of inflammation, perhaps reflecting more acute and aggressive disease. | 26886472 |
| Inflammation, Abnormality of mitochondrial metabolism | Altered Intercellular Communication | Mitochondrial dysfunction may play an important role in abnormal glucose metabolism and systemic inflammation. | 26886611 |
| Ichthyosis Bullosa of Siemens, Liver carcinoma | Altered Intercellular Communication | A Novel and Validated Inflammation-Based Score (IBS) Predicts Survival in Patients With Hepatocellular Carcinoma Following Curative Surgical Resection: A STROBE-Compliant Article. | 26886627 |
| Inflammation, Ichthyosis Bullosa of Siemens, Liver carcinoma, FAM126A gene | Altered Intercellular Communication | As chronic inflammation is involved in the pathogenesis and progression of hepatocellular carcinoma (HCC), we investigated the prognostic accuracy of a cluster of inflammatory scores, including the Glasgow Prognostic Score, modified Glasgow Prognostic Score, platelet to lymphocyte ratio, Prognostic Nutritional Index, Prognostic Index, and a novel Inflammation-Based Score (IBS) integrated preoperative and postoperative neutrophil to lymphocyte ratio in 2 independent cohorts. | 26886627 |
| Chronic liver disease, Hepatitis | Altered Intercellular Communication | Natural killer (NK) cells are important mediators of liver inflammation in chronic liver disease. | 26887815 |
| Refractory anemias, Osteopenia | Altered Intercellular Communication | In conclusion, gene expression of human osteocyte-specific proteins and cytokines was affected by RA-serum, and exogenous recombinant cytokines treatment suggesting that osteocytes could provide a new target to prevent systemic inflammation-induced bone loss in RA. | 26887974 |
| Inflammation, Neuropathy | Altered Intercellular Communication | These data suggest that ML may contribute to TNF-mediated inflammation and focal demyelination by rendering SCs more sensitive to TNF within the nerves of patients with leprous neuropathy. | 26888306 |
| Inflammation, Gout | Altered Intercellular Communication | Although the genetic variants in IL-17 we studied in this research do not appear to be involved in the development of gout in male Chinese Han individuals, the IL-17 cytokine family may participate in gouty inflammation in an undefined way, which requires further validation. | 26890073 |
| Inflammation, Coronary heart disease | Altered Intercellular Communication | This study evaluates the relationship between locally activated PMCs and intracoronary inflammation in stable and unstable coronary disease. | 26890234 |
| Fibrosis Assessment, Hepatitis, FAM126A gene | Altered Intercellular Communication | The risk to develop HCC increases with the severity of liver inflammation and hepatic fibrosis. | 26890368 |
| Cessation of life, Encephalitis, Inflammation, Illness (finding) | Altered Intercellular Communication | Encephalitis, a brain inflammation leading to severe illness and often death, is caused by >100 pathogens. | 26890626 |
| Inflammation, Dry Eye Syndromes | Altered Intercellular Communication | Inflammation aggravated by vitamin D deficiency results in an altered epithelial profile, Bowman layer damage, recruitment of dendritic cells, and altered subbasal nerve plexus features in patients with chronic dry eye disease. | 26890669 |
| Inflammation | Altered Intercellular Communication | Inflammation, represented by CD8 T-cell levels, and persistent C-reactive protein elevation are independent predictors of angiographic restenosis and should therefore be closely monitored in HIV patients undergoing PCI. | 26891035 |
| Inflammation, Metabolic Syndrome X | Altered Intercellular Communication | The reciprocal links between synaptophysin serum levels and the prevalence of metabolic syndrome according to selected low-grade inflammation indices and age-related androgen serum level changes in men. | 26891429 |
| Celiac Disease | Altered Intercellular Communication | Coeliac disease is a chronic immune-mediated inflammation of the small intestine elicited by the gluten ingestion in genetically susceptible people. | 26891431 |
| Inflammation, Communicable Diseases, Chronic otitis, Prolonged, cyclophosphamide/methotrexate/vincristine protocol | Altered Intercellular Communication | Chronic otitis media (COM) describes a variety of symptoms and physical findings that result from prolonged damage to the middle ear by infection and inflammation. | 26891542 |
| vascular inflammations, Mucopolysaccharidosis I | Altered Intercellular Communication | In a model of vascular inflammation, mCRP induced endothelial shedding of MPs and was proinflammatory, while pCRP was anti-inflammatory. | 26891844 |
| Oropharyngeal, Inflammation, Squamous cell carcinoma of the head and neck | Altered Intercellular Communication | Systemic inflammation is an independent predictive marker of clinical outcomes in mucosal squamous cell carcinoma of the head and neck in oropharyngeal and non-oropharyngeal patients. | 26892430 |
| vascular inflammations, Calcification of coronary artery | Altered Intercellular Communication | Association of pooled cohort risk scores with vascular inflammation and coronary artery calcification in Korean adults. | 26892510 |
| vascular inflammations, Calcinosis | Altered Intercellular Communication | The relationship of this new risk scoring system with vascular inflammation and calcification has yet to be examined. | 26892510 |
| vascular inflammations, Calcinosis | Altered Intercellular Communication | The pooled cohort risk equation exhibited significant positive correlations with vascular inflammation but not with calcification in Asian subjects without CVD, suggesting that this novel risk equation may detect early inflammatory changes preceding the structural modification of vessel walls. | 26892510 |
| Inflammation, Fibrosis Assessment, Non-alcoholic Fatty Liver Disease, Metabolic Syndrome X | Altered Intercellular Communication | However, metabolic syndrome is often associated with non-alcoholic fatty liver disease, which leads to liver fibrosis and inflammation that may decrease VLDL production. | 26892520 |
| Inflammation, Impaired cognition, "Alzheimers Disease | Altered Intercellular Communication | The Independent Role of Inflammation in Physical Frailty among Older Adults with Mild Cognitive Impairment and Mild-to-Moderate Alzheimer's Disease. | 26892578 |
| Arterial Stiffness, Calcified (qualifier) | Altered Intercellular Communication | Influence of Thoracic Aortic Inflammation and Calcifications on Arterial Stiffness and Cardiac Function in Older Subjects. | 26892585 |
| Arterial Stiffness, Calcified (qualifier), Hypertensive (finding) | Altered Intercellular Communication | To determine the influence of thoracic aortic inflammation and calcifications on arterial stiffness and cardiac function in hypertensive and normotensive older subjects. | 26892585 |
| Calcinosis | Altered Intercellular Communication | Local thoracic aortic inflammation and calcification were measured by 18 F-fluorodeoxyglucose positron emission tomography/computed tomography imaging. | 26892585 |
| Calcified (qualifier), Inflammation | Altered Intercellular Communication | In the overall population, calcifications of the thoracic descending aorta and inflammation of the ascending aorta accounted for respectively 18.1% (p=0.01) and 9.6% (p=0.07) of AoPWV variation. | 26892585 |
| Calcified (qualifier), Inflammation | Altered Intercellular Communication | Individuals with high levels of calcifications and/or inflammation had higher AoPWV (p=0.003). | 26892585 |
| Inflammation, Hypertension, CTCAE, Calcified (qualifier) | Altered Intercellular Communication | This study highlights the importance of local ascending aortic inflammation as a potential major actor in the determination of PPA while calcifications and hypertension are more linked to AoPWV. | 26892585 |
| Inflammation | Altered Intercellular Communication | Assessment of PPA in the very elderly could provide complementary information to improve diagnostic and therapeutic strategies targeting ascending aortic inflammation. | 26892585 |
| ARCN1 gene, Inflammation | Altered Intercellular Communication | Chronic inflammation associated with COPD is thought to contribute to this risk. | 26893553 |
| ARCN1 gene, Inflammation, Cerebrovascular accident | Altered Intercellular Communication | Exacerbations of COPD are associated with a rise in inflammation, suggesting that there may be an association between exacerbation frequency and the risk of stroke. | 26893553 |
| Inflammation, Fibrosis Assessment, Lung diseases | Altered Intercellular Communication | Pulmonary disease is the main cause of morbidity and mortality in cystic fibrosis (CF) patients due to exacerbated inflammation. | 26894321 |
| Pneumonitis | Altered Intercellular Communication | Overall, sulindac decrease lung inflammation by a mechanism independent of cycolooxygenase. | 26894321 |
| Inflammation, Aspects of mortality statistics | Altered Intercellular Communication | Actigraphy- and Polysomnography-Measured Sleep Disturbances, Inflammation, and Mortality Among Older Men. | 26894325 |
| Inflammation | Altered Intercellular Communication | Medical and life-style factors also substantially attenuated most sleep-mortality associations, suggesting complex relations between sleep, inflammation, and disease. | 26894325 |
| Liver and Intrahepatic Biliary Tract Carcinoma | Altered Intercellular Communication | Preoperative biliary drainage-related inflammation is associated with shorter survival in biliary tract cancer patients. | 26894390 |
| Inflammation, Primary malignant neoplasm | Altered Intercellular Communication | An association between inflammation and patient prognosis has been reported in various types of cancer. | 26894390 |
| Liver and Intrahepatic Biliary Tract Carcinoma | Altered Intercellular Communication | Preoperative biliary drainage-related inflammation was an independent prognostic factor for shorter OS in biliary tract cancer patients. | 26894390 |
| Inflammation, Bell Palsy | Altered Intercellular Communication | Inflammation is thought to play an important role in the pathogenesis of Bell's palsy (BP). | 26894418 |
| Granulomatosis, Orofacial, Granulomatous inflammation | Altered Intercellular Communication | Orofacial granulomatosis (OFG) is characterized by granulomatous inflammation in the orofacial region. | 26894770 |
| Inflammation, Fibrosis Assessment, Fatty degeneration | Altered Intercellular Communication | Component steatosis, inflammation and ballooning scores, and fibrosis staging were correlated with SWV, and diagnostic accuracy of ARFI for fibrosis was assessed. | 26895403 |
| Inflammation, Fibrosis Assessment, Fatty degeneration, Non-alcoholic Fatty Liver Disease, Obesity | Altered Intercellular Communication | The mean SWV was neither significantly different nor correlating with the obesity classes based on body mass index (BMI), steatosis grades, inflammation grades, ballooning grades, and fibrosis stages of NAFLD. | 26895403 |
| Inflammation, Asthma | Altered Intercellular Communication | Periostin is considered to be a marker of eosinophilic inflammation in patients with asthma. | 26895432 |
| Inflammation, Aortic Stiffness | Altered Intercellular Communication | There appears to be no causal relationship between endothelial function and aortic stiffness, suggesting that they occur in parallel, although they may share common risk factors such as inflammation. | 26896473 |
| Rheumatoid Arthritis, Endothelial dysfunction | Altered Intercellular Communication | Rheumatoid arthritis is a systemic inflammatory condition associated with increased cardiovascular risk that may be due to underlying endothelial dysfunction and subsequent aortic stiffening. | 26896473 |
| Fibrosis Assessment, Hepatitis, Chronic, Lymphoproliferative Disorder of the Skin | Altered Intercellular Communication | Taken together, our results demonstrate that infiltrating monocytes may play a pathological role in exacerbating chronic liver inflammation and fibrosis in CLD. | 26896599 |
| Fibrosis Assessment, Hepatitis, Lymphoproliferative Disorder of the Skin | Altered Intercellular Communication | MCP-1 may be involved in the monocyte infiltration and progression of liver inflammation and fibrosis in CLD. | 26896599 |
| Inflammation, Fibrosis Assessment | Altered Intercellular Communication | Regarding the stage of fibrosis, patients with advanced fibrosis were older and had more insulin resistance and more inflammation compared with patients that had mild fibrosis. | 26896689 |
| Fibrosis of pancreas, Pancreatitis, Inflammation, Exocrine Pancreas Cell | Altered Intercellular Communication | Chronic pancreatitis (CP), a common background of PDAC occurrence, is morphologically defined as progressive pancreatic fibrosis and inflammation accompanied by pancreatic exocrine cell atrophy. | 26897254 |
| ANOPHTHALMIA AND PULMONARY HYPOPLASIA, Fibrosis Assessment, Inflammation | Altered Intercellular Communication | We recently found that inflammation and fibrosis are independent characteristic histological changes in noncancerous lesions in PDAC patients despite the absence of a past history of clinical CP. | 26897254 |
| Inflammation, Skin Infection, CTCAE, Cellulitis | Altered Intercellular Communication | Hence, AAT may have a role in the healing process in chronic and acute inflammation including skin infection, such as cellulitis. | 26897780 |
| Inflammation, Cellulitis | Altered Intercellular Communication | This possibly suggests a role AAT activity may have in the inflammation cascade in patients with cellulitis. | 26897780 |
| Inflammation, Dental caries, Pain Distress Question | Altered Intercellular Communication | Furthermore, when pathological processes such as caries affect teeth and produce inflammation of the pulp, the pain experienced can be quite intense and debilitating. | 26898566 |
| Inflammation, Squamous cell carcinoma of the head and neck, Neoplasms | Altered Intercellular Communication | In patients with HNSCC, reduced expression of ADO may contribute to excessive inflammation and tumor growth. | 26898925 |
| Inflammation, Periodontitis, Metabolic Syndrome X, palladium, MS gene | Altered Intercellular Communication | Metabolic Syndrome (MS) and chronic oral condition (periodontitis [PD]) are state of inflammation. | 26899213 |
| Inflammation, Neoplasms | Altered Intercellular Communication | Systemic inflammation is a key factor in tumor growth. | 26899471 |
| Inflammation | Altered Intercellular Communication | C-reactive protein and albumin are parameters of systemic inflammation from the Glasgow Prognostic Score (GPS). | 26899471 |
| Inflammation, "Alzheimers Disease", Data types - Address | Altered Intercellular Communication | Clusterin (CLU) is recognized as a secreted protein that is related to the processes of inflammation and immunity in the pathogenesis of Alzheimer's disease (AD). | 26899953 |
| Inflammation | Altered Intercellular Communication | This trend may be affected by the secular increase in height and the sharp upswing in adolescent overweight; these drive increased insulinlike growth factor 1 and chronic inflammation, which may play an etiologic role. | 26900677 |
| Inflammation, Acute-On-Chronic Liver Failure, Septicemia, CRNKL1 wt Allele, Bacterial peritonitis, Encephalopathy, CTCAE 5.0 | Altered Intercellular Communication | BactDNA was associated with spontaneous bacterial peritonitis and blood stream infections (SBP/BSI), acute-on-chronic liver failure (ACLF), encephalopathy and markers of inflammation. | 26901072 |
| Kidney Failure, Chronic, Inflammation | Altered Intercellular Communication | Increased inflammation might be a risk factor of AEMD and LA mechanical dysfunction in ESRD patients. | 26905405 |
| Inflammation, Pancreatic carcinoma, Diabetes Mellitus | Altered Intercellular Communication | Epidemiologic studies show strong associations between pancreatic cancer (PC) and inflammatory stimuli or conditions such as cigarette smoking and diabetes, suggesting that inflammation may play a key role in PC. | 26905587 |
| Inflammation, Primary malignant neoplasm | Altered Intercellular Communication | Studies of dietary patterns and cancer outcomes also suggest that diet might influence an individual's risk of PC by modulating inflammation. | 26905587 |
| Choroiditis | Altered Intercellular Communication | The L/S ratio measured by binarisation of EDI-OCT images was predictive factor for the progression of PPA, subsequent chronic recurrences and total dose of corticosteroid, and may serve as a marker for degree of choroidal inflammation in the VKH disease. | 26906951 |
| Colorectal Carcinoma | Altered Intercellular Communication | Usefulness of Inflammation-Based Prognostic Score in Patients Undergoing Lung Metastasectomy for Colorectal Carcinoma. | 26908239 |
| Acute Kidney Injury, CTCAE, Negative Regulation of Cell Cycle | Altered Intercellular Communication | These divergent patterns of inflammatory signals are consistent with cell cycle arrest (TIMP-2, IGFBP7) and relative protection from acute kidney injury after imaging and stenting. | 26908767 |
| Inflammation, Acute lymphocytic leukemia | Altered Intercellular Communication | ERG is a key regulator of cell proliferation, differentiation, angiogenesis, inflammation, and apoptosis and has recently been found to be overexpressed in acute myeloid and lymphoblastic leukemia. | 26909589 |
| Sialadenitis, Inflammation | Altered Intercellular Communication | During intraoperative consultation, the lesions were identified as benign, atrophic salivary gland with chronic inflammation, or sialadenitis with atypical glands. | 26909791 |
| Chronic sclerosing sialadenitis | Altered Intercellular Communication | Chronic sclerosing sialadenitis (CSS) is a benign chronic inflammatory condition of the salivary gland. | 26909791 |
| Inflammation, Fibrosis Assessment, Neurogenic arthropathy, Ulcer | Altered Intercellular Communication | Three significant local conditions influencing selection and transfer of the flap include (1) distally located forefoot ulcers, (2) extensive subcutaneous fibrosis secondary to frequent inflammation, and (3) Charcot arthropathy. | 26910652 |
| Inflammation, Cardiovascular Diseases | Altered Intercellular Communication | In middle-aged and older samples, perceived subjective socioeconomic status (SSS) is a marker of social rank that is associated with elevated inflammation and cardiovascular disease risk independent of objective indicators of SES (oSES). | 26910797 |
| Inflammation, Stenosis Morphology, Necrosis | Altered Intercellular Communication | Biliary vessel pathology due to alveolar echicococcosis (AE) results in variable combinations of stenosis, necrosis and inflammation. | 26910822 |
| Inflammation, Intervertebral Disc Degeneration, DGCR2 gene | Altered Intercellular Communication | P38MAPK mediates cytokine induced inflammation in nucleus pulposus (NP) cells and involves in multiple cellular processes which are related to intervertebral disc degeneration (IDD). | 26911458 |
| Inflammation, DGCR2 gene | Altered Intercellular Communication | Hence, Our study suggests that selectively targeting p38 isoforms could ameliorate the inflammation in IDD and regard IDD progression. | 26911458 |
| Granulomatous inflammation | Altered Intercellular Communication | However, among nodes with granulomatous inflammation, ca-TBFB exhibited higher sensitivity (90%) than TBNA (33%). | 26912301 |
| Inflammation, Amyloidosis, Data types - Address | Altered Intercellular Communication | This activation, correlating positively with the amyloid load, implies a relationship between amyloidosis and inflammation in the PS2APP AD mouse model. | 26912428 |
| Inflammation | Altered Intercellular Communication | Administration of the adjuvants led to an influx of activated inflammatory cells into the muscle but to little systemic inflammation measured by serum cytokine levels. | 26912628 |
| Communicable Diseases, Inflammation, cell injury | Altered Intercellular Communication | We chose to target the inflammasome, a molecular complex capable of detecting infection and cell damage and of triggering IL-1b-driven inflammation. | 26912628 |
| Inflammation | Altered Intercellular Communication | The most common benign diagnosis was chronic inflammation (94 patients) by pericardial biopsy. | 26913680 |
| Chronic pain, Chronic inflammation | Altered Intercellular Communication | We did not experience any other mesh-related complications, such as protrusion, chronic pain, or chronic inflammation, during the follow-up period. | 26913817 |
| Inflammation, Fibrosis Assessment | Altered Intercellular Communication | The authors conclude that CK-903 is a useful adjunctive tool that will allow for a quicker, less costly, and more accurate diagnosis of LPP given its ability identify colloid bodies even in the setting of significant inflammation and fibrosis and its advantages over direct immunofluorescence of low cost, short preparation time, and lack of need for a specialized fluorescent microscope. | 26913845 |
| Inflammation, "Alzheimers Disease", Data types - Address | Altered Intercellular Communication | Chronic activation of the complement system and induced inflammation are associated with neuropathology in Alzheimer's disease (AD). | 26914463 |
| Inflammation, Malignant Neoplasms | Altered Intercellular Communication | Final diagnosis was IgG4-RD in 28, malignancy in 29, IgG4-unrelated inflammation in 35, and undetermined cause in 2 subjects. | 26914555 |
| Inflammation, T-Cell Receptors delta-Chain | Altered Intercellular Communication | The MCP-1 concentration was markedly elevated at the second vitrectomy, implying an association between the prolonged inflammation after vitrectomy and complications, especially TRD. | 26915745 |
| Inflammation, Breast Carcinoma | Altered Intercellular Communication | Results suggest that targeting emotion regulation may help to break the cycle between inflammation and sickness symptoms in women with breast cancer. | 26916219 |
| ARCN1 gene, Inflammation | Altered Intercellular Communication | Increased daily movement associates with reduced mortality among COPD patients having systemic inflammation. | 26916560 |
| ARCN1 gene, Inflammation, Chronic Obstructive Airway Disease | Altered Intercellular Communication | Emerging research demonstrates an interrelationship between systemic inflammation, physical activity and premature all-cause mortality among chronic obstructive pulmonary disease (COPD) patients. | 26916560 |
| ARCN1 gene, Inflammation | Altered Intercellular Communication | Physical activity may help to promote survival among COPD patients, particularly those with elevated inflammation. | 26916560 |
| Inflammation | Altered Intercellular Communication | The inflammatory responses evoked by artificial organs and implantation of devices like biosensors and guide wires can lead to acute and chronic inflammation, largely limiting the functionality and longevity of the devices with negative effects on patients. | 26916758 |
| Inflammation | Altered Intercellular Communication | Increased peripheral inflammation in asymptomatic leucine-rich repeat kinase 2 mutation carriers. | 26917005 |
| Inflammation | Altered Intercellular Communication | The results suggest that peripheral inflammation is higher in a percentage of subjects carrying the LRRK2 G2019S mutation. | 26917005 |
| Inflammation, Asthma | Altered Intercellular Communication | Serum periostin is a potential biomarker of response to therapies that target type 2 inflammation in asthma. | 26917610 |
| Inflammation, Neoplasm Metastasis, Appendiceal Neoplasms | Altered Intercellular Communication | Chronic inflammation masquerading as an appendiceal tumour with peritoneal metastasis: the challenge of diagnosis and the lessons learnt. | 26917796 |
| Communicable Diseases, Neoplasms | Altered Intercellular Communication | The differential diagnosis includes neoplasms, inflammatory conditions, infectious conditions, and scar. | 26918968 |
| Pain Distress Question, Pleurisy, Pneumothorax | Altered Intercellular Communication | Specifically, 0.6% was pneumothorax, 0.3% was cytotoxic agent-induced pleural inflammation, 0.5% was pain at puncture location, and 0.3% was failure of HIPEC procedure. | 26919243 |
| Parkinson Disease, Inflammation, palladium | Altered Intercellular Communication | Previous studies have suggested that chronic systemic inflammation increases the risk of Parkinson's disease (PD). | 26919462 |
| Aortic Aneurysm, Abdominal | Altered Intercellular Communication | Positron Emission Tomography and Magnetic Resonance Imaging of Cellular Inflammation in Patients with Abdominal Aortic Aneurysms. | 26919936 |
| APP gene, Inflammation, Aortic Aneurysm, Abdominal | Altered Intercellular Communication | Inflammation is critical in the pathogenesis of abdominal aortic aneurysm (AAA) disease. | 26919936 |
| APP gene, vascular inflammations | Altered Intercellular Communication | Both (18)F-FDG PET-CT and USPIO-MRI uptake identify vascular inflammation associated with AAA. | 26919936 |
| Inflammation, Fatigue | Altered Intercellular Communication | Thus, extracellular HSPs, particularly HSP90a, may signal fatigue in chronic inflammation. | 26921255 |
| Inflammation | Altered Intercellular Communication | In summary, our results suggest that IFN-a-driven, early regulatory T cell depletion contributes to the development of antiviral immunity, ultimately resulting in the resolution of type 1 inflammation. | 26921346 |
| Inflammation, Cytomegalovirus Infections, Refractory anemias, Arthritis, Immunosenescence | Altered Intercellular Communication | Considering the signs of premature T-cell immunosenescence in arthritis patients, the known effect of CMV latency on speeding up many of these signs in an age-dependent manner and the role of CMV on IFNg-mediated inflammation in healthy elderly and RA, we hypothesized that latent CMV infection accelerates TCR repertoire restriction, loss of CD28, peripheral T-cell proliferation and aberrant IFNg responses in arthritis patients. | 26921739 |
| Inflammation | Altered Intercellular Communication | Serum free light chains are reduced in endurance trained older adults: Evidence that exercise training may reduce basal inflammation in older adults. | 26921802 |
| Inflammation | Altered Intercellular Communication | These findings suggest that long-term endurance training may be beneficial in reducing basal inflammation in older adults as well as elevated FLCs present in inflammatory and autoimmune conditions, often associated with ageing. | 26921802 |
| Chronic Obstructive Airway Disease | Altered Intercellular Communication | Lack of Correlation Between Pulmonary and Systemic Inflammation Markers in Patients with Chronic Obstructive Pulmonary Disease: A Simultaneous, Two-Compartmental Analysis. | 26921918 |
| ARCN1 gene, Inflammation, Chronic Obstructive Airway Disease | Altered Intercellular Communication | The origin of systemic inflammation in chronic obstructive pulmonary disease (COPD) patients remains to be defined, but one of the most widely accepted hypothesis is the 'spill over' of inflammatory mediators from the lung to the circulation. | 26921918 |
| ARCN1 gene, Inflammation | Altered Intercellular Communication | To evaluate the relationship between pulmonary and systemic inflammation in COPD quantifying several inflammatory markers in sputum and serum determined simultaneously. | 26921918 |
| ARCN1 gene, Inflammation | Altered Intercellular Communication | We found no correlation between pulmonary and systemic inflammation in patients with stable COPD, suggesting different pathogenic mechanisms. | 26921918 |
| Pain Distress Question, Exophthalmos, Binocular diplopia, Inflammation | Altered Intercellular Communication | A case is presented of a right frontoethmoidal osteoma with intraorbital invasion in a 43-year-old male, who was seen in the clinic with a proptosis, retro-orbital pain, peri-palpebral inflammation, and binocular diplopia due to muscular route limitation. | 26922136 |
| Inflammation, Cholecystitis, Acute Cholecystitis | Altered Intercellular Communication | Because acute cholecystitis has a different prognosis according to the degree of inflammation, early detection and prompt operation of severe cholecystitis are critical to the success of treatment. | 26922627 |
| Diabetic Nephropathy, Inflammation, Diabetes Mellitus, Non-Insulin-Dependent | Altered Intercellular Communication | Determinants of visfatin in type 2 diabetes patients with diabetic kidney disease: Relationship to inflammation, adiposity and undercarboxylated osteocalcin. | 26922969 |
| Inflammation, Diabetes Mellitus, Non-Insulin-Dependent | Altered Intercellular Communication | The main determinant of visfatin in T2D patients with DKD is inflammation; in normoalbuminuric patients, a positive link to adiposity and altered glycemic control and a trend towards a negative correlation to uOC was observable; the latter relationship was evident in patients without DKD. | 26922969 |
| Depression, CTCAE | Altered Intercellular Communication | Inflammation mediates the association between fatty acid intake and depression in older men and women. | 26923510 |
| Inflammation, Depression, CTCAE | Altered Intercellular Communication | Antioxidants and fatty acids are associated with depression and inflammation, and inflammation appears to predict depression risk; hence, the associations between these nutrients and depression may be mediated by inflammation. | 26923510 |
| Inflammation, Osteoporosis, Postmenopausal | Altered Intercellular Communication | Postmenopausal osteoporosis may be caused, in part, by oxidative stress and inflammation. | 26923532 |
| Inflammation, Venous Engorgement, Abnormality of coagulation, Liver Failure | Altered Intercellular Communication | Increased INR is an independent predictor of all-cause mortality in ADHF patients without anticoagulation, reflecting coagulation abnormalities and hepatic insufficiency, possibly through systemic inflammation, neurohormonal activation and venous congestion. | 26924077 |
| Inflammation, Neoplasm Metastasis, Neoplasms | Altered Intercellular Communication | This pathway is known to play a role in inflammation, tumor growth, invasiveness and metastasis, inhibition of apoptosis and angiogenesis. | 26925639 |
| Vascular Diseases, Inflammation, Somatic dysfunction of lower limb, Acute lymphocytic leukemia, Renal Insufficiency, Dyspnea | Altered Intercellular Communication | Heart and vascular disease (H), objectively measured lower extremity dysfunction (O), systemic inflammation (S), dyspnea (P), impaired renal function (I), and tobacco exposure (T) were independent predictors for all-cause hospitalization (ALL). | 26926337 |
| ARCN1 gene, Inflammation | Altered Intercellular Communication | In the airways of COPD subjects, fibroblast-derived PGE2 may regulate angiogenesis and inflammation through the production of VEGF and IL-8 respectively, suggesting that the increase in expression of COX-2, EP2 and EP4 observed in COPD fibroblasts may contribute to steering the role of PGE2 from homeostatic to pro-inflammatory. | 26926362 |
| Pneumonitis | Altered Intercellular Communication | CD81 and CD48 show different expression on blood eosinophils in systemic sclerosis: new markers for disease and pulmonary inflammation? | 26926492 |
| Inflammation, Fibrosis Assessment | Altered Intercellular Communication | We hypothesized that eosinophils may be activated in the peripheral circulation, thereby increasing their recruitment to affected tissues and contributing to inflammation and fibrosis. | 26926492 |
| Inflammation | Altered Intercellular Communication | In patients with short disease duration, increased CD48 expression was associated with alveolar inflammation as measured by an increased concentration of alveolar nitric oxide (r = 0.76, p = 0.003). | 26926492 |
| Sample Size Calculation, Pneumonitis | Altered Intercellular Communication | Blood eosinophils change phenotype during disease evolution in SSc, and CD48 expression may be used as a biomarker for pulmonary inflammation. | 26926492 |
| Inflammation, Coronary Arteriosclerosis | Altered Intercellular Communication | Here, we report that in monocytes and macrophages of patients with atherosclerotic coronary artery disease (CAD), overutilization of glucose promotes excessive and prolonged production of the cytokines IL-6 and IL-1b, driving systemic and tissue inflammation. | 26926996 |
| Inflammation, physiopathological, Cardiovascular Diseases | Altered Intercellular Communication | In essence, PKM2 serves a previously unidentified role as a molecular integrator of metabolic dysfunction, oxidative stress and tissue inflammation and represents a novel therapeutic target in cardiovascular disease. | 26926996 |
| Cardiovascular Diseases | Altered Intercellular Communication | Abnormal glucose metabolism and enhanced oxidative stress accelerate cardiovascular disease, a chronic inflammatory condition causing high morbidity and mortality. | 26926996 |
| Intracerebral, Inflammation, Ischemic stroke | Altered Intercellular Communication | In summary, we provide the first histologic description of mechanically retrieved intracerebral thrombi regarding biomarkers relevant for inflammation in ischemic stroke. | 26927082 |
| Inflammation, diabetic | Altered Intercellular Communication | Associations between Vitamin B-12 Status and Oxidative Stress and Inflammation in Diabetic Vegetarians and Omnivores. | 26927168 |
| Inflammation, Crypt abscess, Superficial ulcer, Cryptitis, Exacerbation of cGVHD | Altered Intercellular Communication | In contrast, patients with any of 5 histologic features of active inflammation (erosions, cryptitis, crypt abscess, increased neutrophils, or increased eosinophils in the lamina propria) had more flares than patients without those changes (P<0.05). | 26927490 |
| Inflammatory abnormality of the eye | Altered Intercellular Communication | Syphilis, although an uncommon cause of ocular inflammation, is a highly contagious, but curable disease. | 26927522 |
| Inflammation, Idiopathic pulmonary hypertension | Altered Intercellular Communication | Chemokine CXC ligand 13 (CXCL13) has been implicated in perivascular inflammation and pulmonary vascular remodeling in patients with idiopathic pulmonary artery hypertension (IPAH). | 26927848 |
| Crohn Disease | Altered Intercellular Communication | Eosinophils Contribute to Intestinal Inflammation via Chemoattractant Receptor-homologous Molecule Expressed on Th2 Cells, CRTH2, in Experimental Crohn's Disease. | 26928963 |
| Inflammation | Altered Intercellular Communication | Eosinophils contribute to the severity of the inflammation, which is improved by a selective CRTH2 antagonist. | 26928963 |
| HD Term Type, Inflammation | Altered Intercellular Communication | One of the most important causes of ESA resistance is chronic inflammation in hemodialysis (HD) patients. | 26929254 |
| HD Term Type, Inflammation | Altered Intercellular Communication | Neutrophil/lymphocyte (NLR) ratio and platelet/lymphocyte ratio (PLR) were also found to be associated with inflammation in HD patients. | 26929254 |
| ARCN1 gene, Inflammation | Altered Intercellular Communication | This provides further evidence that COPD is a multicomponent disease, involving both airway and systemic inflammation. | 26929615 |
| physiopathological, Bladder neck obstruction | Altered Intercellular Communication | Urothelial Dysfunction, Suburothelial Inflammation and Altered Sensory Protein Expression in Men with Bladder Outlet Obstruction and Various Bladder Dysfunctions: Correlation with Urodynamics. | 26930253 |
| Inflammation, Bladder dysfunction, Bladder neck obstruction | Altered Intercellular Communication | We investigated urothelial integrity, suburothelial inflammation and the expression of sensory proteins in the bladder urothelium of male patients with bladder outlet obstruction and various bladder dysfunctions. | 26930253 |
| Inflammation, Bladder dysfunction, Bladder neck obstruction, physiopathological | Altered Intercellular Communication | Urothelial dysfunction, suburothelial inflammation, cellular apoptosis and alterations in sensory proteins are prominent in bladder dysfunction secondary to bladder outlet obstruction. | 26930253 |
| Inflammation, Diabetes Mellitus, Non-Insulin-Dependent | Altered Intercellular Communication | Evidence suggests that chronic subclinical inflammation plays an important role in the pathogenesis of type 2 diabetes (T2DM). | 26930607 |
| Inflammation, Bile Ducts, Extrahepatic | Altered Intercellular Communication | Differential diagnosis between inflammation and cancer of the extrahepatic biliary tract is a complex task. | 26931011 |
| methyldopa, Inflammation | Altered Intercellular Communication | Inflammation has been implicated in age-related macular degeneration (AMD). | 26931413 |
| Acanthamoeba | Altered Intercellular Communication | Acanthamoeba and their proteins can elicit severe allergic airway inflammation in experimental mice. | 26932171 |
| Acute Kidney Tubular Necrosis, Interstitial inflammation | Altered Intercellular Communication | A relapse in the AAV was suspected but a diagnostic kidney biopsy showed acute tubular necrosis, patchy interstitial inflammation, and calcium phosphate deposits. | 26932179 |
| Cholecystitis, Chronic cholecystitis | Altered Intercellular Communication | Gall stones (GS) cause inflammation of the gall bladder (GB) i.e., chronic cholecystitis (CC) and xantho-granulomatous cholecystitis (XGC) which can result in a thick walled GB (TWGB). | 26932432 |
| Inflammation | Altered Intercellular Communication | Increasing evidence indicates that inflammation plays a vital role in tumorigenesis and progression. | 26933932 |
| Airway structure | Altered Intercellular Communication | Obstructive Sleep Apnoea Modulates Airway Inflammation and Remodelling in Severe Asthma. | 26934051 |
| Asthma | Altered Intercellular Communication | The role of OSA-related systemic and airway neutrophilic inflammation in asthma bronchial inflammation or remodelling has been rarely investigated. | 26934051 |
| Inflammation, Asthma, Osage language | Altered Intercellular Communication | The aim of this study was to compare hallmarks of inflammation in induced sputum and features of airway remodelling in bronchial biopsies from adult patients with severe asthma with and without OSA. | 26934051 |
| Critical Illness, Pneumonitis | Altered Intercellular Communication | These may suggest subtle pulmonary inflammation and support application of real time breath analysis for molecular monitoring in critically ill patients. | 26934167 |
| Inflammation, Nasopharyngeal carcinoma, Neoplasms | Altered Intercellular Communication | Primary tumor inflammation in gross tumor volume as a prognostic factor for nasopharyngeal carcinoma patients. | 26934649 |
| Pneumonitis | Altered Intercellular Communication | A double immunization of Fluzone(r) adjuvanted with CpG elicited the highest level of protection in young adult mice which was associated with increases in influenza specific IgG, elevated HAI titres, reduced viral titres and lung inflammation. | 26934728 |
| Communicable Diseases, Helicobacter pylori, Inflammation, Cognition Disorders | Altered Intercellular Communication | Helicobacter pylori (H. pylori) infection is associated with cognitive deficits in humans, an association potentially mediated or moderated by folate concentration or inflammation. | 26935014 |
| Inflammation, Liver Dysfunction, Arthritis, Pain of right shoulder joint, septic | Altered Intercellular Communication | A 43-year-old Japanese man presented with severe right shoulder pain and a body temperature of 38degC.Blood tests showed inflammation and liver dysfunction, although magnetic resonance imaging did not indicate septic shoulder arthritis. | 26935440 |
| Inflammation, Fibrosis Assessment, Fatty degeneration, Fatty Liver Disease | Altered Intercellular Communication | Simple steatosis (SS) was found in 18 subjects (54.5%), in another 15 (45.5%) signs of inflammation and fibrosis (NASH) were observed. | 26935501 |
| Inflammation | Altered Intercellular Communication | However, the function of group V phospholipase A2 in human M2 activation and T-helper-2 inflammation is ill-defined. | 26936936 |
| Transglutaminases, Nasal Polyps, Eosinophilic inflammation | Altered Intercellular Communication | We report that group V phospholipase A2 and transglutaminase-2 colocalized in macrophages of human nasal polyp tissue obtained from patients with T-helper-2 eosinophilic inflammation, and their coexpression positively correlated with the number of eosinophils in each tissue specimen. | 26936936 |
| Inflammation, Hypoxemia | Altered Intercellular Communication | Prolonged intradialytic hypoxemia was associated with laboratory indicators of inflammation, higher erythropoietin requirements, and higher all-cause hospitalization and mortality. | 26936946 |
| Inflammation, Arthritis | Altered Intercellular Communication | A secondary outcome was an assessment of knee function by Western Ontario and McMaster Universities Arthritis Index and Lequesne Index, knee ROM, and two inflammation markers (C-reactive protein and erythrocyte sedimentation rate). | 26937646 |
| Inflammation | Altered Intercellular Communication | Patterns of inflammation were defined according to the extent and distribution of inflammatory infiltrates within the artery. | 26937893 |
| Inflammation, Cerebrovascular accident, Mental disorders, Atherosclerosis | Altered Intercellular Communication | Neuropsychiatric diseases might enhance stroke development, possibly through inflammation and atherosclerosis. | 26937918 |
| Vitreous inflammatory cells | Altered Intercellular Communication | To compare anterior chamber and vitreous inflammation after intravitreal injection of ranibizumab or aflibercept. | 26938579 |
| Vitreous inflammatory cells, Uveitis | Altered Intercellular Communication | An examiner masked to medication graded anterior chamber and vitreous inflammation 1-2 and 5-7 days after injection according to the Standardization of Uveitis Nomenclature grading scheme. | 26938579 |
| Vasculitis | Altered Intercellular Communication | Biopsy enables early histological proof of a dermal vasculitic inflammation pattern and PCR analysis before subsequent serological controls and proofs. | 26939104 |
| Inflammatory Bowel Diseases | Altered Intercellular Communication | Vitamin D deficiency has been reported in patients with chronic inflammatory conditions, such as rheumatic and inflammatory bowel diseases (IBD). | 26939587 |
| Acute inflammation | Altered Intercellular Communication | Thus, we hypothesized that urinary sCD163 shed by crescent macrophages correlates with active glomerular inflammation. | 26940094 |
| Inflammation | Altered Intercellular Communication | Here we describe the crucial role of SIRT6 in aging and inflammation. | 26940461 |
| Inflammation | Altered Intercellular Communication | These findings confirm the key status of CR and disclose the critical role of SIRT6 on aging and inflammation. | 26940461 |
| Inflammation, Diabetic Retinopathy, GDC Disease Response Terminology | Altered Intercellular Communication | The role of inflammation in pathogenesis of diabetic retinopathy (DR) is getting increasingly recognized. | 26940815 |
| vascular inflammations | Altered Intercellular Communication | Macrophages are key players in atherogenesis, promoting vascular inflammation and arterial remodeling through cysteine cathepsin proteases. | 26941255 |
| HD Term Type, Inflammation, Bone Mineralization | Altered Intercellular Communication | Gelsolin is an actin-binding protein that can modulate inflammation, correlated inversely with hemodialysis (HD) mortality and involved in bone calcification homeostasis. | 26941566 |
| Inflammation, Endothelial dysfunction | Altered Intercellular Communication | Here, some markers of oxidative stress, systemic inflammation, and endothelial dysfunction are analysed in men younger and older than 45 years and in pre- and postmenopausal women. | 26941571 |
| Primary malignant neoplasm | Altered Intercellular Communication | Endothelial cell senescence is characterized by acquisition of senescence-associated secretory phenotype (SASP), able to promote inflammaging and cancer progression. | 26943583 |
| Inflammation, MS gene | Altered Intercellular Communication | YKL-40 is a CSF biomarker of intrathecal inflammation in secondary progressive multiple sclerosis. | 26943959 |
| Inflammation, Atherosclerosis | Altered Intercellular Communication | Hp-induced inflammation may be a risk factor for atherosclerosis in patients with VD. | 26944122 |
| Inflammation, Rupture, Plaque, Atherosclerotic | Altered Intercellular Communication | Progressive inflammation may contribute to the rupture of an atherosclerotic plaque. | 26944327 |
| Inflammation, Traumatic injury | Altered Intercellular Communication | Plasma galectin-3 concentrations have close relation to inflammation, trauma severity and clinical outcome, suggesting that galectin-3 should have the potential to be a good prognostic biomarker after STBI. | 26944570 |
| Inflammation, Atherosclerosis | Altered Intercellular Communication | BACKGROUND Regulated upon activation, normal T cells expressed and secreted (RANTES) is associated with inflammation and atherosclerosis. | 26944934 |
| Malignant Neoplasms | Altered Intercellular Communication | F-fluorodeoxyglucose positron emission tomography--an established modality for evaluating malignancies--exhibits increased uptake under inflammatory conditions. | 26945389 |
| Fever, CTCAE | Altered Intercellular Communication | No statistically significant difference in patients' characteristics, or in incidence of inflammation- or infection-related symptoms was seen between the two groups; nor any significant difference among those who developed fever and those who did not. | 26945658 |
| Pain Distress Question, Inflammation | Altered Intercellular Communication | DNA was genotyped for a priori selected genes involved with pain modulation (ADRB2, OPRM1, AVPR1A, GCH1, and KCNS1) and inflammation (IL1B, TNF/LTA, and IL6). | 26945673 |
| Inflammation, Helicobacter pylori, Carcinogenesis, S100A4 protein, human | Altered Intercellular Communication | Helicobacter pylori cause chronic inflammation favouring gastric carcinogenesis, and its eradication may prevent malignant transformation. | 26945693 |
| Inflammation, Visual Impairment, Atherosclerosis | Altered Intercellular Communication | Hearing and visual impairment were not associated with mortality after adjusting for subclinical atherosclerosis and inflammation. | 26946102 |
| Inflammation, Tooth Loss | Altered Intercellular Communication | We determined anthropometric measures, attachment loss, tooth loss and markers of systemic inflammation. | 26946142 |
| Inflammation, Tooth Loss | Altered Intercellular Communication | Systemic inflammation was associated with tooth loss in men but not in women even in women with wide girth. | 26946142 |
| Delirium | Altered Intercellular Communication | Accumulating evidences suggest that the pathophysiology of delirium results from multiple neurotransmitter system dysfunctions. | 26946964 |
| Delirium | Altered Intercellular Communication | Altogether, these results suggest that delirium rats induced by scopolamine may be correlated with an increased cerebral concentration of 5-HT and dopamine neurotransmitters system; the selective 5-HT(1A) antagoniszts can reverse the delirium symptoms at some extent through tendering PI3K/Akt/mammalian target of rapamycin complex 1 (mTOR) activation-induced NLRP3 activity and then reducing IL-1b release. | 26946964 |
| Muscle Spasticity, Cerebrovascular accident | Altered Intercellular Communication | However, 200-Hz TENS led to plasticity of synaptic transmission from the antagonist to spastic muscles in stroke survivors. | 26949041 |
| Inflammation, Basal cell hyperplasia | Altered Intercellular Communication | The biopsies illustrated significant eosinophilic inflammation, eosinophilic microabscesses and basal cell hyperplasia. | 26949147 |
| Inflammation, Virus Diseases, Impaired T cell function | Altered Intercellular Communication | Persistent viral infections are characterized by the simultaneous presence of chronic inflammation and T cell dysfunction. | 26950238 |
| Inflammation, Virus Diseases, Impaired T cell function | Altered Intercellular Communication | Targeted immunological interventions to disrupt the TNF-mediated link between chronic inflammation and T cell dysfunction might therefore lead to therapies to overcome persistent viral infection. | 26950238 |
| Inflammation | Altered Intercellular Communication | Metformin may play a role in reducing the FGF-21 levels in patients with T2DM, likely through the amelioration of glucose-lipid metabolism and inflammation. | 26950284 |
| Inflammatory Bowel Diseases | Altered Intercellular Communication | Inflammatory bowel disease (IBD) is a heterogeneous chronic inflammatory condition requiring significant healthcare expenditure. | 26950309 |
| Inflammation, Anemia, Chronic disease | Altered Intercellular Communication | Chronic inflammation can lead to anaemia of chronic disease due to the sequestration of iron caused by inflammatory cytokines and the protein hepcidin. | 26950401 |
| Inflammation, Arthritis | Altered Intercellular Communication | There is a link between joint and gut inflammation of unknown etiology in arthritis. | 26950480 |
| Refractory anemias, Arthritis | Altered Intercellular Communication | In separate studies, the accumulation of advanced glycation end-products has been associated with joint inflammation in RA. | 26950480 |
| Swollen Lymph Node, Inflammation | Altered Intercellular Communication | There were no signs of inflammation, no grip on the penile shaft, and no urethral discharge or enlargement of lymph nodes. | 26951088 |
| Ischemia, Inflammation, hearing impairment, Sleep Apnea, CTCAE, AKAP4 protein, human | Altered Intercellular Communication | Sleep apnea (SA) may promote hearing impairment (HI) through ischemia and inflammation of the cochlea. | 26951413 |
| Malignant neoplasm of urinary bladder, Inflammation, Carcinoma, Transitional Cell | Altered Intercellular Communication | Proteins involved in immunity, negative regulation of endopeptidase activity, and inflammation were more prevalent in UGS patients with bladder cancer, whereas proteins with roles in renal system process, sensory perception, and gas and oxygen transport were more abundant in subjects with urothelial carcinoma not associated with UGS. | 26951512 |
| Myocarditis | Altered Intercellular Communication | Cardiac Magnetic Resonance Reveals Signs of Subclinical Myocardial Inflammation in Asymptomatic HIV-Infected Patients. | 26951603 |
| Myocardial fibrosis, Myocarditis, Aortic Stiffness | Altered Intercellular Communication | CMR protocol allowed for the determination of cardiac function, myocardial inflammation, myocardial fibrosis, aortic stiffness, and pericardial fat volume. | 26951603 |
| Myocarditis | Altered Intercellular Communication | CMR parameters indicating myocardial inflammation were elevated in HIV-infected patients (native T1 relaxation times, 1128.3+-53.4 ms versus 1086.5+-54.5 ms; P=0.009; relative T2 signal intensity ratio, 1.6+-0.3 versus 1.4+-0.3; P=0.046; early gadolinium enhancement ratio, 3.1+-1.2 versus 2.1+-0.6; P=0.003). | 26951603 |
| Cardiovascular morbidity, Myocarditis, HIV Infections | Altered Intercellular Communication | Subclinical myocardial inflammation as detected by CMR may be a potential precursor of the increased cardiovascular morbidity and mortality observed in patients with chronic HIV infection. | 26951603 |
| Tissue damage, Inflammation | Altered Intercellular Communication | MST1R is predominantly expressed in the tissue-resident macrophages and is critical for innate immunity that protects organs from tissue damage and inflammation. | 26951679 |
| HD Term Type, Inflammation | Altered Intercellular Communication | Neutrophil-lymphocyte ratio (NLR), defined as the neutrophil count divided by lymphocyte count, is increasingly recognized as a marker of systemic inflammation, but its prognostic value in HD patients is unknown. | 26951970 |
| Ulcer, Vasculitis of large artery, Granulomatous inflammation | Altered Intercellular Communication | Histology of tissue biopsied from the ulcer indicated small vessel vasculitis and granulomatous inflammation. | 26952849 |
| vascular inflammations, Endothelial dysfunction, Diabetes Mellitus, Non-Insulin-Dependent, Cardiovascular Diseases | Altered Intercellular Communication | Endothelial dysfunction, vascular inflammation and oxidative stress have been integrally linked to the pathogenesis of both type 2 diabetes and cardiovascular disease. | 26954484 |
| vascular inflammations, Diabetes Mellitus, Non-Insulin-Dependent | Altered Intercellular Communication | This study tested the hypothesis that AGE may improve endothelial function, oxidative stress, vascular inflammation and insulin resistance in high risk cardiovascular subjects with type 2 diabetes. | 26954484 |
| Depressed mood, Dyssomnias | Altered Intercellular Communication | Preexisting mild sleep disturbance as a vulnerability factor for inflammation-induced depressed mood: a human experimental study. | 26954978 |
| Inflammation | Altered Intercellular Communication | Systemic inflammation has been suggested as a potential mechanism of this association. | 26954978 |
| Dyssomnias, Depressed mood, Depression, CTCAE, Disease susceptibility | Altered Intercellular Communication | Inflammation-induced depressed mood was considerably more severe among females reporting mild sleep disturbance compared with those reporting no sleep disturbance, suggesting that even mild sleep disturbance may increase vulnerability for inflammation-induced depression in females. | 26954978 |
| Inflammation, Atherosclerosis | Altered Intercellular Communication | In silico pathway analysis on PM2.5-associated evmiRNAs identified several key CVD-related pathways including oxidative stress, inflammation, and atherosclerosis. | 26956024 |
| IgG4-Related Sclerosing Disease | Altered Intercellular Communication | IgG4-related disease (IgG4-RD) is a newly recognized fibro-inflammatory condition which disrupts the TJ associated epithelial barrier. | 26956365 |
| Refractory anemias, Inflammation | Altered Intercellular Communication | DcR3 and IL-23 may interact in a feedback loop that aggravates local inflammation in patients with RA. | 26956410 |
| Inflammation, Tuberculosis, Myelolipoma, Genus Histoplasma | Altered Intercellular Communication | There were total of 15 cases comprising of 5 tuberculosis, 5 Histoplasma, 2 acute inflammation, 2 granulomatous inflammation, and 1 myelolipoma. | 26956774 |
| septic | Altered Intercellular Communication | The C-reactive protein to albumin (CRP/Alb) ratio, a novel inflammation-based prognostic score, is associated with outcomes in septic patients. | 26956901 |
| Tissue damage, Inflammation | Altered Intercellular Communication | Neutrophil/lymphocyte ratio (NLR) is shown as a good prognostic marker for inflammation due to tissue damage in recent clinical trials. | 26957274 |
| Inflammation, Sarcopenia | Altered Intercellular Communication | Together, these effects contribute to limit the onset and the progression of sarcopenia, due to the major role played by inflammation in the pathophysiology of this disease. | 26957282 |
| Inflammation, Illness Behavior, Fatigue | Altered Intercellular Communication | Our analyses revealed that inflammation, neurotransmitter regulation, and energy metabolism are likely mechanisms associated with evening fatigue severity; that CTX may contribute to fatigue seen in oncology patients; and that the patterns of gene expression may be shared with other models of fatigue (e.g., physical exercise and pathogen-induced sickness behavior). | 26957308 |
| Inflammation, Illness Behavior, Fatigue | Altered Intercellular Communication | Our analyses revealed that inflammation, neurotransmitter regulation, and energy metabolism are likely mechanisms associated with evening fatigue severity; that CTX may contribute to fatigue seen in oncology patients; and that the patterns of gene expression may be shared with other models of fatigue (e.g., physical exercise and pathogen-induced sickness behavior). | 26957308 |
| Inflammation, Pain Distress Question | Altered Intercellular Communication | Experimental and clinical data suggest a close relationship between inflammation and pain perception. | 26958751 |
| Inflammation, Sepsis, BDI - Functional Impairment, Chronic pain, septic | Altered Intercellular Communication | Since sepsis is the most severe form of systemic inflammation, the primary objective was to evaluate chronic pain states and functional impairment of septic and nonseptic patients 6 months after discharge from ICU. | 26958751 |
| Sepsis, Hyperglycemia, Inflammation, Diabetes Mellitus | Altered Intercellular Communication | Admission hyperglycemia is associated with adverse outcome of sepsis irrespective of the presence or absence of preexisting diabetes by a mechanism unrelated to exaggerated inflammation or coagulation. | 26958752 |
| Ischemia, Inflammation, Diarrhea | Altered Intercellular Communication | It is hypothesized that the diarrhea might be due to ischemia in bowel mucosa or inflammation, but the exact underlying pathophysiological mechanism of the diarrhea is still unknown. | 26959411 |
| Inflammation, Colitis, Ischemic | Altered Intercellular Communication | The results showed endoscopically normal mucosa in the lower GI tract in seven patients without signs of ischemic colitis or inflammation. | 26959411 |
| Hepatocellular Adenoma | Altered Intercellular Communication | Hepatocellular adenomas may enlarge during pregnancy due to marked hormonal stimulation. | 26959805 |
| Inflammation, metabolic disturbance | Altered Intercellular Communication | This first GWAS on CUP provide preliminary evidence that germline genes relating to inflammation (LTA4H), metastatic promotion (TIAM1) in association with lipid metabolic disturbance (chromosome 11 cluster) may contribute to the risk of CUP. | 26959888 |
| Uveal melanoma, Inflammation, Edema | Altered Intercellular Communication | Hyperreflective spots increase in number with increasing central subfield thickness and could be considered as a new clinical biomarker of intraretinal inflammation in patients affected by macular edema secondary to irradiation for uveal melanoma. | 26960014 |
| glycation, vascular inflammations, Diabetes Mellitus, Non-Insulin-Dependent, Atherosclerosis | Altered Intercellular Communication | The receptor for advanced glycation end products (RAGE) plays a key role in the development of vascular inflammation and acceleration of atherosclerosis in type 2 diabetes. | 26960737 |
| methyldopa, Inflammation | Altered Intercellular Communication | Inflammation and immune-mediated processes are pivotal to the pathogenic progression of age-related macular degeneration (AMD). | 26961257 |
| methyldopa, Inflammatory abnormality of the eye | Altered Intercellular Communication | Although plasma levels of C-reactive protein (CRP) have been shown to be associated with an increased risk for AMD, the pathophysiological importance of the prototypical acute-phase reactant in the etiology of the disease is unknown, and data regarding the exact role of CRP in ocular inflammation are limited. | 26961257 |
| Inflammation, Abdominal Pain | Altered Intercellular Communication | The patient was discharged from the hospital on day 4 after the procedure, with no abdominal pain and no peritoneal signs of inflammation. | 26961561 |
| Inflammation, Respiratory Syncytial Virus Infections | Altered Intercellular Communication | The pathological features induced by RSV infection in HIS mice included peribronchiolar inflammation, neutrophil predominance in the bronchioalveolar lavage fluid, and enhanced airway mucus production. | 26962219 |
| Presenile dementia, Inflammation, Depression, CTCAE, Cardiovascular Diseases | Altered Intercellular Communication | Several studies have indicated that early inflammation, cardiovascular disease, and depression in patients were associated with a considerably increased risk of dementia. | 26962833 |
| Inflammation, Swelling | Altered Intercellular Communication | NSAIDs facilitate alleviating RA-associated chronic pain, inflammation, and swelling. | 26962833 |
| Alzheimers Disease", Periodontitis, Impaired cognition, Inflammation | Altered Intercellular Communication | Our data showed that periodontitis is associated with an increase in cognitive decline in Alzheimer's Disease, independent to baseline cognitive state, which may be mediated through effects on systemic inflammation. | 26963387 |
| Inflammation, Data types - Address | Altered Intercellular Communication | Inflammation in AD mice was alleviated by CLN treatment, including the accumulation of GFAP positive cells and the inflammatory cytokines. | 26964005 |
| Fibrosis Assessment, Calcinosis | Altered Intercellular Communication | Microscopic examination of the mass revealed a nodular focus of calcification and fibrosis with focal chronic inflammation of the atrial endocardium. | 26964029 |
| HSPG2 wt Allele, Inflammatory disease of mucous membrane | Altered Intercellular Communication | In patients receiving chemoradiotherapy showing severe oral mucosal inflammation outside the irradiation area or oral mucosal inflammation associated with skin lesions throughout the body, it is necessary to bear in mind the possibility of SJS. | 26964396 |
| ARCN1 gene, Inflammation, Chronic Obstructive Airway Disease | Altered Intercellular Communication | Chronic obstructive pulmonary disease (COPD) patients exhibit chronic inflammation, both in the lung parenchyma and the airways, which is characterised by an increased infiltration of macrophages and T-lymphocytes, particularly CD8+ cells. | 26965295 |
| Inflammation | Altered Intercellular Communication | Resolvin E1 may play a key role in the resolution of acute inflammation when immunonutrition is supplemented with EPA. | 26965712 |
| Cholecystitis | Altered Intercellular Communication | The IR correlated significantly with the presence of acute gallbladder inflammation (p = 0.043). | 26965715 |
| Malnutrition | Altered Intercellular Communication | Dialysis Malnutrition and Malnutrition Inflammation Scores: screening tools for prediction of dialysis-related protein-energy wasting in Malaysia. | 26965758 |
| Plaque, Atherosclerotic | Altered Intercellular Communication | Apolipoprotein B-100 Antibody Interaction With Atherosclerotic Plaque Inflammation and Repair Processes. | 26965851 |
| Inflammation, Cardiovascular Diseases | Altered Intercellular Communication | This study investigated the association between p45 IgG autoantibodies and plaque inflammation in subjects with advanced cardiovascular disease. | 26965851 |
| Inflammation, Dental Plaque | Altered Intercellular Communication | In a subcohort of 195 subjects, endarterectomy samples were analyzed by immunohistochemistry and ELISA to determine plaque constituents and inflammation. | 26965851 |
| Dental Plaque, Plaque, Atherosclerotic | Altered Intercellular Communication | This study confirms previous experimental findings of anti-inflammatory properties of apolipoprotein B-100 p45 antibodies and provides the first clinical evidence of associations between p45 IgG autoantibody levels and atherosclerotic plaque inflammation, plaque repair as well as prevalent and incident cardiovascular events in carotid endarterectomy patients. | 26965851 |
| Malignant tumor of colon, Inflammation, Acute and chronic inflammation | Altered Intercellular Communication | Chronic intestinal inflammation is closely associated with colon cancer development and STAT3 seems to take center stage in bridging chronic inflammation to colon cancer progress. | 26965998 |
| Malignant tumor of colon | Altered Intercellular Communication | Consequently, this study proposes that inflammation-induced Jak-STAT3 signaling leads to colon cancer development through proteasomal degradation of DICER1 by ubiquitin ligase complex of CUL4A(DCAF1), which suggests a novel therapeutic opportunity for colon cancer. | 26965998 |
| Inflammation, Uveal Effusion Syndrome | Altered Intercellular Communication | Presence of uveal effusion and increased number of recurrences of inflammation are significant risk factors. | 26967258 |
| Inflammation, Cardiovascular Diseases | Altered Intercellular Communication | Systemic inflammation may play a role in the link between particulate matter and cardiovascular disease. | 26967353 |
| Breast Carcinoma, Bipolar Disorder | Altered Intercellular Communication | Val66Met BDNF polymorphism as a vulnerability factor for inflammation-associated depressive symptoms in women with breast cancer. | 26967918 |
| Depression, CTCAE | Altered Intercellular Communication | Inflammation contributes to the development of depression in a subset of individuals, but risk factors that render certain individuals particularly vulnerable to inflammation-associated depression are undetermined. | 26967918 |
| Breast Carcinoma, Cognitive | Altered Intercellular Communication | The BDNF Met allele may be a risk factor for inflammation-associated cognitive depressive symptoms among breast cancer survivors. | 26967918 |
| Inflammation, Fibrosis Assessment | Altered Intercellular Communication | Histologically, it showed a chronic inflammation and fibrosis. | 26968047 |
| Congenital cataract | Altered Intercellular Communication | An inflammatory condition may occur in eyes with congenital cataract. | 26968721 |
| Inflammation, Breast Carcinoma | Altered Intercellular Communication | In brief, our results suggested that resveratrol chemosensitizes doxorubicin in combination, through inhibiting breast cancer cells proliferation and invasion, and inducing apoptosis via suppression of chronic inflammation and autophagy. | 26969377 |
| Airway structure, Coughing, Acute upper respiratory infection | Altered Intercellular Communication | Eosinophilic airway inflammation is common in subacute cough following acute upper respiratory tract infection. | 26969485 |
| Coughing, Eosinophilic inflammation | Altered Intercellular Communication | Patients presenting with refractory postinfectious cough may respond to glucocorticosteroids but it is unclear whether airway eosinophilic inflammation exists in those patients. | 26969485 |
| Airway structure, Coughing, Acute upper respiratory infection | Altered Intercellular Communication | We aimed to determine the airway inflammation and causes of subacute cough following acute upper respiratory tract infection (AURTI). | 26969485 |
| Coughing, Airway structure | Altered Intercellular Communication | Subacute cough following AURTI can be attributed to different entities, eosinophilic airway inflammation is common. | 26969485 |
| Inflammation | Altered Intercellular Communication | The activity of the vaccine involves boosting the immune system through the stimulation of the inflammation in the bladder. | 26969570 |
| Inflammation, Endothelial dysfunction, Depression, CTCAE | Altered Intercellular Communication | Associations of low grade inflammation and endothelial dysfunction with depression - The Maastricht Study. | 26970354 |
| Inflammation, Depression, CTCAE, Endothelial dysfunction | Altered Intercellular Communication | The pathogenesis of depression may involve low-grade inflammation and endothelial dysfunction. | 26970354 |
| Inflammation, Endothelial dysfunction, Depressive disorder, Depressive Symptoms | Altered Intercellular Communication | We aimed to evaluate the independent associations of inflammation and endothelial dysfunction with depressive symptoms and depressive disorder, and the role of lifestyle factors in this association. | 26970354 |
| Inflammation, Endothelial dysfunction, Depressive disorder, Depressive Symptoms | Altered Intercellular Communication | Biomarkers of inflammation (hsCRP, TNF-a, SAA, sICAM-1) and endothelial dysfunction (sICAM-1, sE-Selectin) were univariately associated with depressive symptoms and depressive disorder. | 26970354 |
| Inflammation, Endothelial dysfunction, Depressive disorder, Cardiovascular Diseases | Altered Intercellular Communication | The sum scores of inflammation and endothelial dysfunction were associated with depressive disorder after adjustment for age, sex, type 2 diabetes, kidney function and prior cardiovascular disease (OR 1.54, p=0.001 and 1.40, p=0.006). | 26970354 |
| Inflammation, Endothelial dysfunction, Depressive Symptoms | Altered Intercellular Communication | The sum score of inflammation was also independently associated with depressive symptoms, while the sum score of endothelial dysfunction was not. | 26970354 |
| Inflammation, Endothelial dysfunction, Depressive disorder | Altered Intercellular Communication | Inflammation and endothelial dysfunction are both associated with depressive disorder, independent of lifestyle factors. | 26970354 |
| Inflammation, Endothelial dysfunction, Depression, CTCAE | Altered Intercellular Communication | Our results might suggest that inflammation and endothelial dysfunction are involved in depression. | 26970354 |
| ARCN1 gene, Airway structure, mucus secretion, Chronic Obstructive Airway Disease, Lung diseases | Altered Intercellular Communication | Chronic Obstructive Pulmonary Disease (COPD) is a chronic and progressive lung disease characterized by irreversible airflow obstruction, airway inflammation, oxidative stress and, often, mucus hypersecretion. | 26970503 |
| Cytomegalovirus Infections, Inflammation, Ulcerative Colitis | Altered Intercellular Communication | Cytomegalovirus Infection in Ulcerative Colitis is Related to Severe Inflammation and a High Count of Cytomegalovirus-positive Cells in Biopsy Is a Risk Factor for Colectomy. | 26971053 |
| Inflammation | Altered Intercellular Communication | The course and severity of the disease were analysed, with inflammation graded histologically across the range 0-3. | 26971053 |
| Inflammation | Altered Intercellular Communication | The CMV IHC-positive patients had lower haemoglobin [median 11.0g/dl vs 12.0; p = 0.028] and albumin [median 29.5g/l vs 33.1; p = 0.038] levels and more intense histological inflammation [p = 0.020] compared with CMV IHC-negative patients. | 26971053 |
| Cytomegalovirus Infections, Inflammation | Altered Intercellular Communication | CMV infection was related to more severe inflammation. | 26971053 |
| Inflammation, Fibrosis Assessment, Disease | Altered Intercellular Communication | These active, terminally differentiated, cytokine-secreting effector CD4(+) T cells are now linked to a human disease characterized by chronic inflammation and fibrosis. | 26971690 |
| Granulomatous inflammation, Tuberculosis, Pulmonary | Altered Intercellular Communication | An immunosuppressive condition might inhibit air-space pneumonia to become granulomatous inflammation as an initial stage of pulmonary tuberculosis. | 26972247 |
| Inflammation, Swelling, Bulla, ACTH Deficiency, Isolated | Altered Intercellular Communication | Typically IAD presents as inflammation of the skin surface characterised by redness, and in extreme cases, swelling and blister formation. | 26972998 |
| Coughing | Altered Intercellular Communication | Objective Cough Frequency, Airway Inflammation, and Disease Control in Asthma. | 26973014 |
| Airway structure, Coughing, Bronchial Hyperreactivity | Altered Intercellular Communication | Asthma control is thought to be determined by the degree of airway inflammation and hyperresponsiveness but how these factors relate to cough frequency is unclear. | 26973014 |
| Coughing, Asthma, Airway structure | Altered Intercellular Communication | The goal of this study was to investigate the relationships between objective cough frequency, disease control, airflow obstruction, and airway inflammation in asthma. | 26973014 |
| Coughing, Symptoms, Asthma, Airway structure | Altered Intercellular Communication | Ambulatory cough frequency monitoring provides an objective assessment of asthma symptoms that correlates with standard measures of asthma control but not airflow obstruction or airway inflammation. | 26973014 |
| Inflammation, Valve Device, Abnormal degeneration | Altered Intercellular Communication | The etiologic relation of SS to the valve lesions is not clear pathologically in this case, however, chronic inflammation related to immunologic reactions in SS could have some effect on exacerbation for degeneration of the valve tissue. | 26973276 |
| Inflammation | Altered Intercellular Communication | Platelet-to-lymphocyte ratio (PLR) was proposed as a novel indirect marker of inflammation. | 26974393 |
| Inflammatory disease of mucous membrane | Altered Intercellular Communication | Histopathologic findings were chronic mucosal inflammation (87.3%), ulceration (74.5%), lymphocytic aggregation (69.1%), and granulomatous fusion (58.2%). | 26974755 |
| Inflammation, Hepatobiliary Disorder, Malnutrition | Altered Intercellular Communication | Predictors of mortality included the following: functional status (odds ratio [OR] = 2.87), liver disease (OR = 3.61), malnutrition (OR = 1.43), age greater than 65 years (OR = 2.39), American Society of Anesthesiologists 4 or higher (OR = 2.90), systemic inflammation (OR = 1.99), and contamination (OR = 2.15). | 26975662 |
| Communicable Diseases, Inflammation | Altered Intercellular Communication | These data suggest roles for tryptophan metabolism, infectious burden, activation of host defense, and detoxification through CYP1A-mediated pathways in mechanisms related to elevated inflammation, whereas CYP-mediated o-oxidation and PPAR-a activation may be related to decreased inflammation in older adults. | 26975982 |
| Inflammation, Primary malignant neoplasm | Altered Intercellular Communication | Inflammation has been reported to play an important role in cancer progression, and several inflammatory markers, such as the neutrophil to lymphocyte ratio (NLR) and modified Glasgow prognostic score (mGPS), have been reported to be prognostic markers. | 26976989 |
| Chronic Obstructive Airway Disease | Altered Intercellular Communication | Controlled Mechanical Ventilation Attenuates the Systemic Inflammation of Severe Chronic Obstructive Pulmonary Disease Exacerbations. | 26977971 |
| Eosinophilic inflammation | Altered Intercellular Communication | The airway eosinophilic inflammation markers (FeNO more than 25 ppb and eosinophil counts of more than 150 cells/u) were elevated in 63% of the patients. | 26978414 |
| Eosinophilic inflammation | Altered Intercellular Communication | Traditional treatment is not always effective, as many patients, despite their treatment, have uncontrolled SA and continuously increased markers of airways eosinophilic inflammation. | 26978414 |
| Cessation of life, Inflammation | Altered Intercellular Communication | Despite complex treatment inflammation progressed in 5 of 8 patients followed by death. | 26978620 |
| Inflammation, Community | Altered Intercellular Communication | Psychological Resources Are Independently Associated with Markers of Inflammation in a Middle-Aged Community Sample. | 26979423 |
| Inflammation, Granuloma | Altered Intercellular Communication | High airway-centered FF score was associated with airway-centered acute inflammation (P=.028) and peribronchiolar granulomas (P=.042). | 26980038 |
| Metabolic Syndrome X | Altered Intercellular Communication | Intracellular metabolism of glucocorticoid hormones plays an important role in the pathogenesis of metabolic syndrome and regulates, among many physiological processes, collagen metabolism in skin. | 26980090 |
| Inflammation | Altered Intercellular Communication | The inflammatory involvement of vital organs may represent a dangerous and life-threatening situation: in particular, the inflammation of the myocardial tissue of the heart may lead to severe consequences since the clinical history of the disease may be completely asymptomatic, any clinical sign may be lacking, thus preventing correct diagnosis and treatment. | 26980245 |
| Inflammation | Altered Intercellular Communication | Patients with AFRS experienced a more-prolonged QoL benefit from surgical and targeted medical intervention compared with those with CRSsNP, which may reflect the severity of inflammation that they presented with compared with other CRS subtypes. | 26980383 |
| Smoking, Diabetes Mellitus | Altered Intercellular Communication | Smoking, diabetes mellitus and inflammatory conditions did not influence the results. | 26980433 |
| Inflammation | Altered Intercellular Communication | Our data suggest that the immune cell composition of the synovium and the IFP is similar, and includes activated cells that could contribute to inflammation through secretion of proinflammatory cytokines. | 26980579 |
| Inflammation, Pathology, Atherosclerosis | Altered Intercellular Communication | Endocan is a marker for vascular pathologies and an important mediator of angiogenesis, strongly associated with inflammation, vascular endothelial dysfunction, and atherosclerosis. | 26980772 |
| Inflammation, Neoplasms | Altered Intercellular Communication | However, IDO expression associated with poor survival in the sub-groups with primary tumor stage T2-T4 and in the sub-group with strong inflammation in tumors' invasive front. | 26982018 |
| Refractory anemias, Inflammation, Pain Distress Question | Altered Intercellular Communication | Previous studies have suggested a link between inflammation and central sensitization of pain in patients with RA. | 26983452 |
| Airway structure, Nephrotic Syndrome, Hypertension, CTCAE | Altered Intercellular Communication | We herein report the case of an 18-year-old boy who developed nephrotic syndrome and hypertension after upper airway inflammation. | 26984084 |
| Inflammation, Chronic disease | Altered Intercellular Communication | Diets rich in fruits and vegetables (FV), which contain (poly)phenols, protect against age-related inflammation and chronic diseases. | 26984113 |
| Inflammation | Altered Intercellular Communication | These results suggest that (poly)phenols derived from onions, turmeric, red grapes, green tea and acai berries may help reduce the release of pro-inflammatory mediators in people at risk of chronic inflammation. | 26984113 |
| Data types - Address | Altered Intercellular Communication | Our findings provide evidence for a modulatory role of inflammation-induced Ab phagocytosis and degradation by newly recruited peripheral immune cells in the pathophysiology of AD. | 26984535 |
| Inflammation, Primary malignant neoplasm, Diabetes Mellitus, Heart Diseases, Lung diseases | Altered Intercellular Communication | Protein S-glutathionylation, the formation of a mixed disulfide between glutathione and protein thiols, is an oxidative modification that has emerged as a new signaling paradigm, potentially linking oxidative stress to chronic inflammation associated with heart disease, diabetes, cancer, lung disease, and aging. | 26984580 |
| Inflammation, Fibrosis Assessment, Hypertrophy | Altered Intercellular Communication | However, transforming growth factor b and bone morphogenetic protein receptor II signaling, and hypertrophy, apoptosis, fibrosis, capillary density, inflammation, and cardiac metabolism, as well, were similar between mutation carriers and noncarriers. | 26984938 |
| Diabetes Mellitus, Non-Insulin-Dependent, Inflammation, Polycystic Ovary Syndrome | Altered Intercellular Communication | Soluble CD163, which is identified as a marker of inflammation and type II diabetes, is elevated in polycystic ovary syndrome. | 26985764 |
| Inflammation, Impaired cognition, Immune System Diseases, HIV Infections | Altered Intercellular Communication | Microbial translocation from the gut is associated with immune dysfunction, persistent inflammation, and likely plays a role in the pathogenesis of neurocognitive dysfunction during HIV infection. | 26986173 |
| Inflammation, MUCOPURULENT CERVICITIS, Infertility, Prostate Cancer Outcomes Study, Endometriosis, Polycystic Ovary Syndrome | Altered Intercellular Communication | Our data showed that genital C. trachomatis infection was associated with infertility issues, inflammation in the reproductive tract (mucopurulent cervicitis or endometriosis), irregular menstrual cycles and polycystic ovarian syndrome (PCOS). | 26987367 |
| Cerebral Angiitis, Inflammation, Ischemic stroke, Structure of intracranial artery | Altered Intercellular Communication | In patients with ischemic stroke of unknown cause cerebral vasculitis is a rare but relevant differential diagnosis, especially when signs of intracranial artery stenosis are found and laboratory findings show systemic inflammation. | 26988083 |
| Giant Cell Arteritis, Arteritis | Altered Intercellular Communication | Temporal artery biopsy confirmed the suspected diagnosis of a giant cell arteritis and dedicated vessel wall MRI performed later supported the suspected intracranial large artery inflammation. | 26988083 |
| Inflammation | Altered Intercellular Communication | Inflammation has been suggested to play a vital role in the pathogenesis. | 26988292 |
| allergic inflammation, Craniosynostosis, Chronic sinusitis | Altered Intercellular Communication | Interleukin (IL)-9 and IL-17C have been known to play a role in allergic inflammation, yet, their roles in chronic rhinosinusitis (CRS) are not well defined. | 26989880 |
| Carcinoma, Tuberculosis, Xanthogranulomatous cholecystitis, Acute suppurative inflammation, Adenocarcinoma | Altered Intercellular Communication | The lesions diagnosed on FNA cytology included carcinoma (predominantly adenocarcinoma), xanthogranulomatous cholecystitis (XGC), acute suppurative inflammation and tuberculosis. | 26990137 |
| Granulomatous inflammation, Fibrosis Assessment, Granuloma, Necrosis | Altered Intercellular Communication | A skin biopsy specimen showed dermal fibrosis and patchy granulomatous inflammation in the upper-to-mid dermis that was associated with a perivascular, lymphohistiocytic infiltrate along with granulomas and necrosis in the subcutaneous fat. | 26990341 |
| Communicable Diseases, Inflammation, Enterobius vermicularis, Acute appendicitis NOS (disorder) | Altered Intercellular Communication | vermicularis in acute appendicitis has previously been questioned, with some studies identifying infection as a precursor for inflammation of the appendix, with others refuting such a link. | 26990375 |
| Inflammation, Infestation | Altered Intercellular Communication | Appendices were categorized by degree of inflammation and infestation with E . | 26990375 |
| Inflammation, Enterobius vermicularis | Altered Intercellular Communication | vermicularis did not have concurrent acute inflammation of the appendix on histological examination. | 26990375 |
| Appendicular colic, Inflammation, Infestation, Acute appendicitis NOS (disorder) | Altered Intercellular Communication | The question remains as to whether infestation is protective of inflammation or whether infestation causes appendiceal colic and subsequent appendicectomy of a non-inflamed appendix, thereby protective of the morbidity of acute appendicitis. | 26990375 |
| Inflammation, Fibrosis Assessment | Altered Intercellular Communication | Additionally, CK18 showed a significant correlation with the presence and the degree of hepatic fibrosis (p = 0.003) and inflammation (p<0.001) in liver histology. | 26990427 |
| Polyomavirus, Renal tubular disorder, Interstitial inflammation, Tubulitis Assessment | Altered Intercellular Communication | Polyomavirus nephropathy is characterized histopathologically by evidence of viral replication and acute tubular injury with interstitial inflammation, tubulitis, and intranuclear inclusions. | 26992480 |
| Inflammation, Perfusion (biological), Vascular occlusion, Amniotic Fluid | Altered Intercellular Communication | Placentas were analyzed for gross and histologic variables including maternal malperfusion, amniotic fluid infection sequence, chronic inflammation, and fetal vascular obstruction. | 26992676 |
| MS gene, Inflammation, Atrophic retina, Optic Nerve | Altered Intercellular Communication | Retinal atrophy in multiple sclerosis (MS) is secondary to optic nerve focal inflammation and to injury of the posterior visual pathway. | 26993116 |
| Inflammation, Microvascular Angina | Altered Intercellular Communication | Sex differences in the impact of CYP2C19 polymorphisms and low-grade inflammation on coronary microvascular disorder. | 26993229 |
| Inflammation, Microvascular Angina | Altered Intercellular Communication | We examined sex differences in the impact of the CYP2C19 genotype and low-grade inflammation on coronary microvascular disorder (CMVD). | 26993229 |
| Inflammation | Altered Intercellular Communication | CYP2C19 PM genotype may be a new candidate risk factor for CMVD via inflammation exclusively in the female population. | 26993229 |
| Inflammation, Prostate carcinoma | Altered Intercellular Communication | It remains to be established whether the link between inflammation and BPH progression supported by our findings reflects a progressive failure of the immune system leading to decreased immune surveillance and development of prostate cancer. | 26993768 |
| Inflammation, Pain Distress Question | Altered Intercellular Communication | While a myriad of chemical factors in the cytokine network stimulate local joint inflammation and pain, Interleukin 1 (IL-1) is widely recognized as a key offender and a potential therapeutic target. | 26994310 |
| Inflammation, Nerve Degeneration | Altered Intercellular Communication | These findings indicate an important role of ferritin light chains in neurodegeneration, that is linked to chronic inflammation processes and the associated activation of the microglia rich of L chains. | 26994418 |
| Colitis | Altered Intercellular Communication | All forms of colonic inflammation presented a dramatic decrease in apoptosis compared with healthy colon. | 26995182 |
| Gastrointestinal inflammation | Altered Intercellular Communication | Care has to be taken when analysing immune response in intestinal inflammation, as location-specific differences may be relevant. | 26995182 |
| Inflammation | Altered Intercellular Communication | Oligoclonal immunoglobulin G bands (OCBs) restricted to the cerebrospinal fluid indicate intrathecal inflammation. | 26995358 |
| Gastrointestinal inflammation | Altered Intercellular Communication | Fecal calprotectin (CPT) has been widely used in gastrointestinal inflammation, but comprehensive data in GI-GVHD are lacking. | 26995779 |
| Inflammation | Altered Intercellular Communication | Because hsCRP was related to FGF-21 and TNF-a was associated with leptin, these findings suggest a link between increased levels of these adipokines and hepatokines and chronic inflammation. | 26996723 |
| Inflammation, Migraine Disorders | Altered Intercellular Communication | Increased levels of C-reactive protein (CRP) have been considered as a marker in assessing neurogenic inflammation of migraine patients. | 26996761 |
| Inflammation, Nasal Polyps, Chronic sinusitis | Altered Intercellular Communication | CXCL12 and its receptor CXCR7 may contribute to eosinophilic inflammation in patients with chronic sinusitis and nasal polyps. | 26996902 |
| Inflammation, Helicobacter pylori Positive | Altered Intercellular Communication | For Helicobacter pylori-positive patients, acute inflammation was more severe in the lesser curvature of the antrum compared with the greater curvature. | 26997223 |
| Intestinal metaplasia, Inflammation | Altered Intercellular Communication | Inflammation is most severe in the lesser curvature of the antrum, which corresponds to a higher predilection to develop intestinal metaplasia at this site. | 26997223 |
| Pneumonitis | Altered Intercellular Communication | Chemokine CCL18, which has been linked to pulmonary inflammation, is an interesting candidate, but data have not been consistent. | 26997242 |
| Inflammation, Hypertension, CTCAE | Altered Intercellular Communication | The outcome was favorable with corticosteroids alone with regression of the clinical signs, disappearance of inflammation, and control of hypertension. | 26997400 |
| Inflammation, Malnutrition | Altered Intercellular Communication | Inflammation seems to affect prognosis more than malnutrition in this setting and may therefore guide clinicians' attitude towards therapeutic choices. | 26999249 |
| Inflammation, Traumatic injury | Altered Intercellular Communication | The relative size of the MPh populations differed between kidneys: the pDC population was bi-modally distributed being less than 2% of DC in two kidneys without severe injury and over 35% in the remaining three with low grade injury in the absence of morphological evidence of inflammation. | 26999595 |
| Inflammation | Altered Intercellular Communication | Systemic inflammation may be responsible for the rise in endocan levels following CPB. | 26999704 |
| Inflammation | Altered Intercellular Communication | Circulating levels of thioredoxin (Trx), a potent anti-oxidant that modulates inflammation, cell growth and apoptosis, are increased in various critical care conditions. | 27000227 |
| ARCN1 gene, Inflammation, Chronic Obstructive Airway Disease, Arterial Stiffness | Altered Intercellular Communication | We tested the hypothesis that in elderly COPD patients airflow limitation is associated with arterial stiffness and the relationship, if any, is related to endothelial function and systemic inflammation. | 27000864 |
| Inflammation, Thrombosis, Avian ventriculitis, Infarction, Cerebral Hemorrhage, Cerebritis | Altered Intercellular Communication | Observed pathological processes were inflammation of medium-large arteries in 30 brains (97 %), cerebral haemorrhage in 24 (77 %), cerebritis in 24 (77 %), thrombosis in 21 (68 %), infarction in 19 (61 %) and ventriculitis in 19 (of 28 cases, 68 %). | 27001057 |
| Vascular occlusion | Altered Intercellular Communication | Inflammation of medium-large arteries led to obstruction of the vascular lumen in 14 (of 31 cases, 45 %). | 27001057 |
| Infarction, vascular inflammations, Thrombosis | Altered Intercellular Communication | Vascular inflammation was associated with infarction and thrombosis of brain parenchymal vessels. | 27001057 |
| Airway structure | Altered Intercellular Communication | Asthma is a complex disease with heterogeneous features of airway inflammation and remodeling. | 27001157 |
| Airway structure, Hypertrophy | Altered Intercellular Communication | ASM enlargement occurred independently of features of airway inflammation and remodeling, whereas it was associated with PAR-2 overexpression and higher alveolar tryptase (P <= .02) and KLK14 (P <= .03) levels. | 27001157 |
| Hemorrhage, Neoplasms, Necrosis, Neurilemmoma, Osteogenesis, Intravascular papillary endothelial hyperplasia, Adrenal Cortical Adenoma | Altered Intercellular Communication | The adrenocortical adenomas (size, 1-13 cm; 25%-95% hemorrhage) showed clear cell change in the neoplastic area (10%-80% of the tumor), 19 showed focal calcification (1 with ossification), 11 showed areas of papillary endothelial hyperplasia, 10 showed scattered lymphoplasmacytic inflammation, 6 showed benign cortical tissue extending beyond the adrenal capsule into soft tissue, 1 showed necrosis in the form of ghost cells, 2 showed lipomatous change, and 6 were associated with incidental benign lesions (1 cortical cyst, 1 schwannoma, and 4 myelolipomas). | 27001431 |
| Inflammation | Altered Intercellular Communication | Findings suggest that mediation pathways for the overall association between chronic inflammation and QoL may differ markedly across particular outcome constructs. | 27001461 |
| Disability, Inflammation, Pain Distress Question | Altered Intercellular Communication | Pain and disability linked to chronic inflammation appear to play a small but significant mediating role in the overall reduction in QoL observed among older adults with biomarker evidence of chronic inflammation. | 27001461 |
| Deficit, Acute lymphocytic leukemia | Altered Intercellular Communication | The findings suggest that survivors of ALL should receive counseling regarding lifestyle and undergo screening for hormonal deficits to minimize the risk of low BMD and frailty. | 27001572 |
| Pancreatitis | Altered Intercellular Communication | Duct obliteration can lead to recurrent episodes of pancreatic inflammation mimicking acute and chronic pancreatitis. | 27001600 |
| ARCN1 gene, Chronic Obstructive Airway Disease, Inflammatory disorder | Altered Intercellular Communication | Chronic Obstructive Pulmonary Disease (COPD) is a chronic inflammation disease of the respiratory tract. | 27001650 |
| Inflammation, Asthma | Altered Intercellular Communication | The study of gene-environment interactions enables us to further understand the pathogenesis of asthma and inflammation. | 27001655 |
| Delirium, Inflammation | Altered Intercellular Communication | Unadjusted and adjusted odds ratios (95% CI) of delirium for residents exposed to at least one inflammation antagonist medication were 0.53 (0.34, 0.81) and 0.60 (0.38, 0.92), respectively. | 27001903 |
| Inflammation, Vestibular Diseases | Altered Intercellular Communication | The inflammatory responses and possible resolution obstacles of inflammation participated in persistent vestibular function disorders after irradiation. | 27002826 |
| Inflammation, Heart failure | Altered Intercellular Communication | Relationships Among Cognitive Function and Cerebral Blood Flow, Oxidative Stress, and Inflammation in Older Heart Failure Patients. | 27002943 |
| Inflammation, Impaired cognition | Altered Intercellular Communication | We investigated the relative contributions of cerebral blood flow velocity (BFV), oxidative stress, and inflammation to HF-associated cognitive impairment. | 27002943 |
| Inflammation, Serous, Traumatic injury, Hereditary | Altered Intercellular Communication | No differences in tubal injury or inflammation were seen when comparing the sporadic serous cancer group and the control group or within the hereditary group. | 27003156 |
| Inflammation, Brain Injury, Chronic | Altered Intercellular Communication | This small study, no correlation with chronic tubal injury or inflammation was identified. | 27003156 |
| Inflammation, Calcinosis, Abnormal degeneration, Aortic valve disorder | Altered Intercellular Communication | Calcific aortic valve disease is associated with inflammation and calcification, thus the osteoprotegerin (OPG), receptor activator of nuclear factor kB (RANK) and its ligand (RANKL) system involved in osteoclastogenesis and inflammation may play a significant role in valve degeneration. | 27003233 |
| Inflammatory abnormality of the eye | Altered Intercellular Communication | In total, 32 patients with ocular inflammation were treated with adalimumab. | 27003323 |
| Inflammation, Inflammatory disorder | Altered Intercellular Communication | Adalimumab was moderately effective in controlling inflammation in a group of highly pre-treated cases of ocular inflammatory disease. | 27003323 |
| Inflammation, Hypertensive (finding), Aneurysm | Altered Intercellular Communication | NLR as a marker of chronic low-grade inflammation may play a role in the pathogenesis of aneurysm of the ascending aorta in hypertensive patients. | 27003944 |
| Inflammation, Dysplasia, Squamous cell carcinoma, Parasitic Diseases, Pemphigus Vulgaris, Lichen Planus, Keratosis | Altered Intercellular Communication | Histologically Lichen Planus was the most common lesion (32.5%), followed by chronic nonspecific inflammation in (22.5%), keratosis without dysplasia (10%), keratosis with dysplasia (8.8%), Pemphigus vulgaris (7.5%), fungal infestation (5%) and Squamous cell carcinoma (3.8%). | 27004341 |
| Inflammation, Endothelium | Altered Intercellular Communication | In conclusion, among patients with low-grade systemic inflammation, an oral NC significantly improved cholesterol profile and attenuated the degree of systemic inflammation and endothelial injury. | 27004462 |
| Inflammation, Metabolic Diseases, Diabetes Mellitus, Non-Insulin-Dependent | Altered Intercellular Communication | Type 2 diabetes mellitus (T2D) is a metabolic disease with inflammation as an important pathogenic background. | 27007651 |
| Inflammation, Coin lesion of lung | Altered Intercellular Communication | We examined Aspergillus-specific IgG levels in patients who met the following criteria: (i) chronic (duration of >3 months) pulmonary or systemic symptoms, (ii) radiological evidence of a progressive (over months or years) pulmonary lesion with surrounding inflammation, and (iii) no major discernible immunocompromising factors. | 27008878 |
| ARCN1 gene, Inflammation, Cardiovascular Diseases, Atherosclerosis, Pulmonary Emphysema, Arterial Stiffness, Cardiovascular system | Altered Intercellular Communication | In an independent cohort of 186 patients with COPD and 110 control subjects, pDES levels were higher in COPD patients with cardiovascular disease and correlated with arterial stiffness (p<0.05).In COPD, excess elastin degradation relates to cardiovascular comorbidities, atherosclerosis, arterial stiffness, systemic inflammation and mortality, but not to emphysema or emphysema progression. | 27009168 |
| Acute Coronary Syndrome, Observation Method - Coagulation, Inflammation, GDC AJCC Clinical Stage Terminology | Altered Intercellular Communication | The aim of this study was to determine whether markers of inflammation and coagulation are associated with short-term particulate matter exposure and predict major adverse cardiovascular events at 360 d in patients with acute coronary syndrome (ACS). | 27009348 |
| Inflammation, Scleritis, Necrotizing, Non-necrotizing granulomatous inflammation | Altered Intercellular Communication | Serum IL-22 levels from patients with active scleritis were correlated with type of scleritis (non-necrotizing and necrotizing), degree of inflammation (0-4+ :<=2+ and >2+), and associated systemic disease. | 27009382 |
| Inflammation, Scleritis | Altered Intercellular Communication | There was no statistical association with scleritis type, degree of inflammation, or associated systemic disease. | 27009382 |
| Inflammation, Laminar necrosis, Necrosis, Calcified (qualifier), Intimal proliferation | Altered Intercellular Communication | Histopathologic features evaluated were: the severity of inflammation and intimal hyperplasia, both graded on a semiquantitative scale (mild = 1, moderate = 2, severe = 3), the presence of intraluminal acute thrombosis, calcifications, giant cells, fibrinoid necrosis and laminar necrosis. | 27009904 |
| Nasal inflammation, Necrosis | Altered Intercellular Communication | Additionally, they often coexist with nasal inflammation and mucosal necrosis. | 27010643 |
| Alzheimers Disease", Inflammation, Data types - Address | Altered Intercellular Communication | One of the factors that contribute to Alzheimer's disease (AD) is the DNA damage caused by oxidative stress and inflammation that occurs in nerve cells. | 27010693 |
| Inflammation, Liver carcinoma | Altered Intercellular Communication | Dynamic change of the systemic immune inflammation index predicts the prognosis of patients with hepatocellular carcinoma after curative resection. | 27010778 |
| Inflammation, Gout, Spondylarthritis, Rheumatoid Arthritis, Inflammatory disorder | Altered Intercellular Communication | In our study, we analyzed power Doppler signals in inflammatory joint diseases including gout, calcium pyrophosphate deposition disease, rheumatoid arthritis, spondyloarthritis and others and correlated power Doppler signals with synovial white blood count and with serologic markers of inflammation. | 27010839 |
| Inflammation, Parasitic Diseases, Septicemia, Boundary Shift Integral | Altered Intercellular Communication | An association between blood stream infections (BSI) and HTLV-1 seropositivity in Indigenous Australians might result from HTLV-1 mediated inflammation and parasite coinfections that provide portals of entry for bacteria. | 27011343 |
| Inflammation | Altered Intercellular Communication | We hypothesize that airway LXA4 levels increase to compensate bronchoconstriction and suppress acute inflammation, and that spontaneous bronchodilatation after EIB may be due to LXA4. | 27012012 |
| Cogan-Reese syndrome, Inflammation, Anemia | Altered Intercellular Communication | Anemia Due to Inflammation in an Anti-Coagulated Patient with Blue Rubber Bleb Nevus Syndrome. | 27012056 |
| Inflammation, Fever, CTCAE | Altered Intercellular Communication | At admission, the patient also presented fever and increased laboratory parameters of systemic inflammation (ferritin 308 mcg/L, C-reactive protein (CRP) 244 mg/L). | 27012056 |
| Inflammation, Anemia | Altered Intercellular Communication | Unexpectedly, chronic severe anemia due to systemic inflammation was diagnosed in an old anticoagulated patient with BRNBS. | 27012056 |
| Inflammation, Fever, CTCAE, Gastrointestinal Hemorrhage | Altered Intercellular Communication | Fever and inflammation disappeared without any acute gastrointestinal bleeding and improvement of hemoglobin levels at three-month follow up. | 27012056 |
| Inflammation, Anemia, Gastrointestinal Hemorrhage | Altered Intercellular Communication | Surprisingly, anemia was mainly caused by systemic inflammation instead of chronic gastrointestinal bleeding. | 27012056 |
| Inflammation, Heart failure, Depression, CTCAE | Altered Intercellular Communication | Depression and markers of inflammation as predictors of all-cause mortality in heart failure. | 27013355 |
| Inflammation, Heart failure | Altered Intercellular Communication | In patients with heart failure (HF) depressive symptoms have been associated with mortality, as well as biological risk factors, including inflammation, nitric oxide (NO) regulation, and oxidative stress. | 27013355 |
| Inflammation, Bipolar Disorder | Altered Intercellular Communication | We investigated the joint predictive value of depressive symptoms, inflammation and NO regulation on all-cause mortality in patients with HF, adjusted for covariates. | 27013355 |
| Inflammation, Bipolar Disorder | Altered Intercellular Communication | When combined, both depressive symptoms and markers of inflammation and NO regulation remained significantly associated with all-cause mortality. | 27013355 |
| Inflammation, Heart failure, Bipolar Disorder | Altered Intercellular Communication | Depressive symptoms and markers of inflammation and NO regulation are codominant risk factors for all-cause mortality in heart failure. | 27013355 |
| Inflammation | Altered Intercellular Communication | Our findings suggest that inflammation has the potential to influence expression of genes, and potentially intestinal proteins, important to drug disposition and response. | 27013401 |
| Inflammation, Hypoxia | Altered Intercellular Communication | Angiotensinogen expression is down regulated in human ileal CD, particularly in the presence of inflammation and current cigarette smoking, implicating the mesenteric vasculature and mucosal hypoxia as co-factors in ileal CD pathogenesis. | 27014752 |
| Inflammation, Atrial Fibrillation, Chronic Kidney Diseases | Altered Intercellular Communication | Inflammation plays a role in increased incidence of AF in patients with chronic kidney disease (CKD); reactive oxygen species and inflammatory markers which are increased in patients with CKD were found to affect the proper functioning of the intracellular ion channels, connexions (transmembrane proteins found in intercellular gap junctions), and electrical homogeneity of the extracellular matrix which are essential for electrical stability and proper conduction of electrical impulses in the atrium. | 27015175 |
| Hepatitis | Altered Intercellular Communication | The serum BAFF levels were significantly stratified in each 2 liver inflammation stage. | 27015216 |
| Hepatitis | Altered Intercellular Communication | Similarly, the serum IP-10 levels were significantly stratified in each 2 liver inflammation stage. | 27015216 |
| Fibrosis Assessment, Hepatitis, Insemination, Artificial, Homologous | Altered Intercellular Communication | In patients without advanced fibrosis (F3 or more), the serum BAFF level significantly correlated with serum IP-10 level (rs = 0.658, P < 0.001), whereas in patients with advanced fibrosis, the serum BAFF level significantly correlated with serum IP-10 level (rs = 0.542, P < 0.001).In conclusion, both BAFF and IP-10 are useful for predicting the degree of liver inflammation activity in AIH. | 27015216 |
| Hepatitis, Insemination, Artificial, Homologous | Altered Intercellular Communication | BAFF and IP-10 may have the common clinical implication for liver inflammation activity for AIH patients. | 27015216 |
| Inflammation | Altered Intercellular Communication | PCSK9 in relation to coronary plaque inflammation: Results of the ATHEROREMO-IVUS study. | 27015246 |
| Inflammation, physiopathological | Altered Intercellular Communication | The receptor of AGEs (RAGE) has an essential contribution to cellular dysfunction driven by chronic inflammatory responses while TGF-b1 is critical in both dermal homeostasis and inflammation. | 27015414 |
| Psoriasis | Altered Intercellular Communication | Psoriasis Skin Inflammation-Induced microRNA-26b Targets NCEH1 in Underlying Subcutaneous Adipose Tissue. | 27015452 |
| Dermatitis | Altered Intercellular Communication | However, the mechanistic links between psoriatic skin inflammation and systemic comorbidities remain largely unknown. | 27015452 |
| Psoriasis | Altered Intercellular Communication | MicroRNAs (miRNAs) are recently discovered gene regulators that play important roles in psoriasis skin inflammation. | 27015452 |
| Dermatitis | Altered Intercellular Communication | We conclude that this miRNA may serve as a mechanistic link between psoriatic skin inflammation and its systemic comorbidities. | 27015452 |
| Inflammation, Primary malignant neoplasm | Altered Intercellular Communication | To summarize, the inflammatory cytokines and steroid hormones may reflect the degree of inflammation in betel nut-chewing males and the oral cancer subjects. | 27016129 |
| Inflammation, Primary malignant neoplasm | Altered Intercellular Communication | To summarize, the inflammatory cytokines and steroid hormones may reflect the degree of inflammation in betel nut-chewing males and the oral cancer subjects. | 27016129 |
| Granulomatous inflammation, Carcinoma | Altered Intercellular Communication | EBUS-TBNA provided a definitive diagnosis (predominantly carcinoma and granulomatous inflammation) in 71%. | 27016425 |
| Inflammation, Atherosclerosis | Altered Intercellular Communication | Peroxisome proliferator-activated receptor-g (PPARg), liver X receptor-a (LXRa), and PPARg co-activator-1a (PGC-1a) are nuclear factors that regulate lipid metabolism and inflammation implicated in atherosclerosis. | 27016616 |
| Aneurysm, Dissecting, Vasculitis | Altered Intercellular Communication | Although vessel wall inflammation is suspected as one of the causes of cerebral arterial dissection, there have been few reports regarding the application of HRMR-VWI to arterial dissection. | 27017283 |
| Inflammation, Hemorrhage, Disease | Altered Intercellular Communication | In markers of periodontal inflammation, bleeding on probing was correlated with disease activity score 28 (r = 0.128, p = 0.041), RA disease duration (r = 0.211, p = 0.001), erythrocyte sedimentation rate (ESR; r = 0.141, p = 0.023), anti-cyclic citrullinated peptide antibody (r = 0.183, p = 0.009), and anti-citrullinated a-enolase peptide-1 antibody (r = 0.143, p = 0.025). | 27017391 |
| Inflammation, Disease | Altered Intercellular Communication | Periodontal inflammation was correlated with RA disease duration, ESR, and anti-citrullinated protein antibodies. | 27017391 |
| Inflammation | Altered Intercellular Communication | Serum androgens and inflammation might not contribute to insulin resistance in these women. | 27018331 |
| Inflammation, Hyperplasia, Neoplasms | Altered Intercellular Communication | Microscopic findings showed that the tumor consisted of inflammation of a lymph node, lymphoid follicles with hyperplasia of germ center and granulomatous inflammation with giant cells, and there was no malignant finding. | 27018406 |
| Inflammation, Atherosclerosis | Altered Intercellular Communication | Self-reported experiences of discrimination and inflammation among men and women: The multi-ethnic study of atherosclerosis. | 27018725 |
| Overactive, physiopathological, diabetic | Altered Intercellular Communication | Urothelial Dysfunction and Chronic Inflammation in Diabetic Patients with Overactive Bladder. | 27018971 |
| Inflammation, diabetic, physiopathological, Overactive Bladder | Altered Intercellular Communication | To investigate urothelial dysfunction, suburothelial inflammation, and muscarinic receptor expression in diabetic patients with overactive bladder (OAB). | 27018971 |
| Inflammation, physiopathological | Altered Intercellular Communication | Urothelial dysfunction and chronic suburothelial inflammation may contribute to the pathogeneses of OAB. | 27018971 |
| Inflammation | Altered Intercellular Communication | However, DM does not aggravate the severity of urothelial inflammation in OAB patients. | 27018971 |
| Inflammation, Cholangitis | Altered Intercellular Communication | Liver sclerostin was associated with the severity of cholangitis (p = 0.02) and indirectly with the degree of lobular inflammation (p = 0.03). | 27019303 |
| ARCN1 gene, Airway structure | Altered Intercellular Communication | The airways of COPD patients are often colonized with bacteria leading to increased airway inflammation. | 27019597 |
| Post-Traumatic Stress Disorder, Inflammation | Altered Intercellular Communication | An investigation of vago-regulatory and health-behavior accounts for increased inflammation in posttraumatic stress disorder. | 27020074 |
| Post-Traumatic Stress Disorder, Inflammation, Cardiovascular Diseases | Altered Intercellular Communication | Posttraumatic stress disorder (PTSD) has been linked to chronic inflammation, a condition that poses a risk for cardiovascular disease. | 27020074 |
| Post-Traumatic Stress Disorder, Inflammation | Altered Intercellular Communication | Attenuated vagal activity has been proposed as a potential mediator of PTSD and inflammation, although associated behavioral health risks-namely cigarette smoking and alcohol dependence-might also account for that link. | 27020074 |
| Post-Traumatic Stress Disorder, Inflammation, Tumor necrosis | Altered Intercellular Communication | Inflammation was quantified by fasting serum concentrations of C-reactive protein (CRP), tumor necrosis factor (TNF)-a, interleukin (IL)-10, and thymus- and activation-regulated chemokine (TARC)/CCL17 collected from 85 participants with PTSD and 82 without PTSD. | 27020074 |
| Post-Traumatic Stress Disorder, Inflammation | Altered Intercellular Communication | PTSD symptom severity was associated with increased inflammation (b=.18, p=.02). | 27020074 |
| Post-Traumatic Stress Disorder, Inflammation | Altered Intercellular Communication | Together, RSA, smoking status, and lifetime alcohol dependence accounted for 95% of the effect of PTSD symptom severity on inflammation. | 27020074 |
| Inflammation, Depression, CTCAE | Altered Intercellular Communication | Since major depression is associated with inflammation, we examined whether GDF-15 levels are elevated in patients with late-life depression. | 27020076 |
| Inflammation, Seminoma | Altered Intercellular Communication | OCT4 staining increases the detection of lymphatic/vascular invasion in pure seminoma of the testis obscured by prominent lymphohistiocytic inflammation. | 27020494 |
| Inflammation, Neoplasms, Testis, Seminoma, Lymphovascular Invasion 1 | Altered Intercellular Communication | Lymphatic/vascular invasion (LVI) is an important prognostic feature in pure seminoma of the testis, a tumour that may be associated with lymphohistiocytic inflammation (LHI). | 27020494 |
| Autoimmune Diseases, Dermatitis, Atopic, Nephritis, Interstitial, Autoimmune Thyroid Disease Pathway | Altered Intercellular Communication | This particular pattern has not been associated with systemic autoimmune rheumatic disorders (SARD) but has been associated with other inflammatory conditions such as interstitial nephritis, autoimmune thyroid disease and atopic eczema as well as being found in healthy individuals. | 27020500 |
| Inflammation, Fibrosis Assessment | Altered Intercellular Communication | One-hundred and twenty-four KAs were characterized with respect to age of the lesions both clinically and histopathologically, in addition to phenotypic characteristics such as cellular atypia, infiltration, inflammation and fibrosis. | 27020606 |
| Sepsis, Inflammation, Heat-Shock Proteins 70, Aplastic | Altered Intercellular Communication | Neither radiochemotherapy, nor inflammation or sepsis during aplasia induced HSP70 release into the serum. | 27020764 |
| Pain Distress Question, Inflammation | Altered Intercellular Communication | An abrupt onset was a consistent feature, with pain, complete loss of function, and local evidence of inflammation. | 27020953 |
| Inflammation, Fever, CTCAE | Altered Intercellular Communication | A single patient had a fever and 6 patients had laboratory evidence of systemic inflammation. | 27020953 |
| Inflammation | Altered Intercellular Communication | However, the clinical roles of plaque-related vulnerability and inflammation remain unclear. | 27021042 |
| Inflammation, Dental Plaque | Altered Intercellular Communication | Plaque inflammation and neovascularization have both been shown as important characteristics in vulnerable plaque. | 27021564 |
| Inflammation, Cerebral Infarction, Dental Plaque | Altered Intercellular Communication | Acute cerebral infarction patients showed intense contrast enhancement and inflammation in carotid plaque, and different types of plaque had various degrees of enhancement, suggesting that contrast-enhanced ultrasound and hs-CRP might be used for plaque risk stratification. | 27021564 |
| Inflammation, Wheezing, Pulmonary Dysfunction | Altered Intercellular Communication | Airways inflammation may precede pulmonary dysfunction in wheezing individuals. | 27021575 |
| Degenerative polyarthritis | Altered Intercellular Communication | The lincRNA p50-associated cyclooxygenase 2-extragenic RNA (PACER) and 2 novel chondrocyte inflammation-associated lincRNAs (CILinc01 and CILinc02) were differentially expressed in both knee and hip OA cartilage compared to non-OA cartilage. | 27023358 |
| Degenerative polyarthritis, Degenerative disorder of cartilage | Altered Intercellular Communication | Differential expression of CILinc01 and CIinc02 in hip and knee OA cartilage, and their role in modulating cytokine production during the chondrocyte inflammatory response, suggest that they may play an important role in mediating inflammation-driven cartilage degeneration in OA. | 27023358 |
| Inflammation, Venous Thromboembolism | Altered Intercellular Communication | Increased inflammation as reflected by higher circulating IL-6 and increased homocysteine concentrations may represent mechanisms linking 25(OH)D deficiency to greater risks of CVD and perhaps venous thromboembolism. | 27023449 |
| Degenerative polyarthritis, Inflammation | Altered Intercellular Communication | We further showed histone deacetylase 4 (HDAC4) is a direct target of miR-365, which mediates mechanical stress and inflammation in OA pathogenesis. | 27023516 |
| Inflammation, Pneumonia, Interstitial, Idiopathic Pulmonary Fibrosis | Altered Intercellular Communication | IPF is a form of chronic, progressive fibrosing interstitial pneumonia and has more scarring, less inflammation, and poorer prognosis than most other ILD forms. | 27023695 |
| Thrombus, Inflammation | Altered Intercellular Communication | Most of the cutaneous manifestations of APS have been found to be thrombotic on histopathology without evidence of perivascular inflammation. | 27024977 |
| Inflammation, Atherosclerosis, Coronary heart disease, Choline Dehydrogenase, Mitochondrial | Altered Intercellular Communication | The arachidonate 5-lipoxygenase enzyme plays a crucial role in mediating inflammation to maintain homeostasis, yet certain allelic variants of the 5-lipoxygenase gene, ALOX5, may increase risk of atherosclerosis and coronary heart disease (CHD). | 27025886 |
| Inflammation, Endometriosis, Female Genital Diseases, Coronary heart disease, Choline Dehydrogenase, Mitochondrial | Altered Intercellular Communication | Endometriosis is a prevalent gynecologic disease associated with systemic chronic inflammation, heightened oxidative stress, and atherogenic lipid profile that may increase women's risk for coronary heart disease (CHD). | 27025928 |
| nervous system disorder | Altered Intercellular Communication | The present case illustrates a possible link between auto-inflammation and auto-antibody-mediated neurological diseases. | 27026266 |
| Adenocarcinoma | Altered Intercellular Communication | Many adenocarcinomas and inflammatory conditions exhibit increased expression of ADAMs, 'a disintegrin and metalloproteinases'. | 27026568 |
| Inflammation | Altered Intercellular Communication | This is important because older adults regularly experience acute increases in systemic inflammation that may predispose older adults to cardiovascular events through dysregulation of blood pressure. | 27027865 |
| Arterial Stiffness, Inflammation, Endothelial dysfunction | Altered Intercellular Communication | Ageing is characterized by chronic, low-grade inflammation that is related to endothelial dysfunction and arterial stiffness. | 27027865 |
| Inflammation, Cardiovascular Physiological Phenomena | Altered Intercellular Communication | Physical activity can protect older adults (OAs) from cardiovascular dysfunction and increased inflammation. | 27027865 |
| Inflammation, Endothelial dysfunction | Altered Intercellular Communication | Acute inflammation causes transient endothelial dysfunction and arterial stiffening in younger adults (YAs), but may not have the same effect in OAs. | 27027865 |
| Inflammation, Impaired | Altered Intercellular Communication | We hypothesized that acute inflammation would increase blood pressure (BP) and endothelial impairment to a greater extent in OAs versus YAs, but that physical activity would be protective. | 27027865 |
| Inflammation, FRONTOMETAPHYSEAL DYSPLASIA 1 | Altered Intercellular Communication | We conclude that acute inflammation reduced FMD only in YAs and reduced BP only in OAs. | 27027865 |
| Cardiac complication, Inflammation Mediators | Altered Intercellular Communication | Clinicians should be aware that all OAs are vulnerable to inflammation-mediated reductions in BP and cardiovascular complications. | 27027865 |
| Inflammation, Diabetes Mellitus, Non-Insulin-Dependent | Altered Intercellular Communication | Improvement of insulin resistance and inflammation is a basic strategy in the management of type 2 diabetes. | 27028002 |
| Inflammation, Diabetes Mellitus, Non-Insulin-Dependent | Altered Intercellular Communication | In conclusion, resistant dextrin supplementation can modulate inflammation and improve insulin resistance in women with type 2 diabetes. | 27028002 |
| Esophageal carcinoma | Altered Intercellular Communication | Chronic inflammation-associated genomic instability paves the way for human esophageal carcinogenesis. | 27028857 |
| Inflammation, Primary malignant neoplasm, Esophageal carcinoma | Altered Intercellular Communication | Chronic inflammation is associated with increased risk of cancer development, whereas the link between chronic inflammation and esophageal carcinogenesis is still obscure heretofore. | 27028857 |
| Inflammation, Squamous cell carcinoma of esophagus | Altered Intercellular Communication | Endoscopic esophageal biopsies from 109 individuals from Chaoshan littoral, a high-risk region for esophageal squamous cell carcinoma (ESCC), were examined to evaluate the association between chronic inflammation and histological severity, while additional 204 esophageal non-tumor samples from patients with ESCC were collected. | 27028857 |
| Inflammation | Altered Intercellular Communication | Significantly positive correlation was observed between degree of chronic inflammation and esophageal precursor lesions (rs = 0.37, P < 0.01). | 27028857 |
| Inflammation | Altered Intercellular Communication | Immunohistochemical analysis showed that oxidative DNA damage level was positively correlated with the degree of chronic inflammation (rs = 0.21, P < 0.05). | 27028857 |
| Inflammation, precancerous lesions | Altered Intercellular Communication | We found that the extent of DSBs was progressively increased with inflammation degree (P < 0.01) and the progression of precancerous lesions (P < 0.001). | 27028857 |
| Esophageal carcinoma | Altered Intercellular Communication | Collectively, these findings provide evidence linking chronic inflammation-associated genomic instability with esophageal carcinogenesis and suggest possibilities for early detection and intervention of esophageal carcinogenesis. | 27028857 |
| Inflammatory abnormality of the eye | Altered Intercellular Communication | Thus, we demonstrated that CNV lesions trigger a systemic immune response, augmenting local ocular inflammation via the infiltration of IL-17-producing gdT-cells, which are presumably recruited to the eye in a C5a-dependent manner. | 27029558 |
| Refractory anemias, Inflammation | Altered Intercellular Communication | Therefore, the precise cellular distribution of PDPN and it's relationships with inflammation was studied in RA treated with biologic disease-modifying anti-rheumatic drugs (DMARD) or conventional DMARDs (cDMARD). | 27030253 |
| Refractory anemias, Inflammation, Degenerative polyarthritis | Altered Intercellular Communication | PDPN+ cells were immunostained by NZ-1 mAb, and scored (3+; >50%/ area, 2+; 20%- 50%, 1+; 5%-20%, 0: <5%) in synovial tissues from RA treated with biologic DMARDs (BIO, n=20) or cDMARD (n=20) for comparison with osteoarthritis (OA, n=5), followed by cell grading of inflammation and cell-typing. | 27030253 |
| Refractory anemias, Arthritis, Joints | Altered Intercellular Communication | PDPN may have potential of a new marker of residual arthritis in local joints for inflammation-associated severe RA. | 27030253 |
| Intraocular inflammation | Altered Intercellular Communication | There were no signs of intraocular inflammation, or change in lens status or increase in intraocular pressure throughout the study. | 27030277 |
| Inflammation | Altered Intercellular Communication | Xanthogranulomatous inflammation, which is known to occur in several viscera, is rarely found to affect the pancreas. | 27030447 |
| Pneumonitis | Altered Intercellular Communication | Conversely, immunization with a formalin-inactivated RSV (FI-RSV) vaccine induced high levels of inflammatory chemokines and cytokines of the Th2- and Th17-mediated types of immune responses, as well as severe lung inflammation and histopathology. | 27030590 |
| Inflammation, Uterine Fibroids, Hamartoma, Granuloma | Altered Intercellular Communication | Seven (3.8%) cases had significant lesions, including leiomyoma (n=2), endobronchial tuberculosis (n=2), chronic inflammation (n=1), hamartoma (n=1) and benign granuloma (n=1). | 27030677 |
| Dental Plaque | Altered Intercellular Communication | Our results suggest the possible existence of a new mechanism of intercellular communication in the plaque milieu. | 27031176 |
| Viral myocarditis, Myocarditis, Erectile dysfunction | Altered Intercellular Communication | Based on studies pointing to a role for the proinflammatory cytokine interleukin-1 in myocardial inflammation and contractile dysfunction, we treated a patient with fulminant viral myocarditis with the interleukin-1 receptor blocking agent anakinra. | 27031379 |
| Heart failure, Myocarditis, Erectile dysfunction | Altered Intercellular Communication | Clinical and experimental evidence suggests that interleukin-1 blockade is effective against myocardial inflammation and contractile dysfunction, thus representing a promising candidate for the treatment of inflammatory heart failure. | 27031379 |
| Inflammation, Physiologic Intraocular Pressure | Altered Intercellular Communication | Graft and nongraft-associated complications such as graft detachment, graft failure, graft rejection, anterior chamber inflammation, and intraocular pressure decompensation did not differ significantly between first and fellow eyes (P > 0.05, respectively). | 27032023 |
| Inflammation, Impaired cognition | Altered Intercellular Communication | Inflammation, Oxidation, Caloric Expenditure and Cognitive Impairment in Brazilian Elderly Assisted at Primary Care. | 27033057 |
| Inflammation, Specimen Type - Fistula, Diverticulitis | Altered Intercellular Communication | The fistula was of a primary vascular enteric type and was accentuated by the inflammation arising from the diverticulitis. | 27033287 |
| Inflammation, Fasciitis, Myositis, CTCAE 5.0 | Altered Intercellular Communication | CT scan revealed fasciitis and myositis of the right rectus abdominis muscle with subcutaneous inflammation involving the fasciae and muscle. | 27033292 |
| Inflammation, Arthritis | Altered Intercellular Communication | Specialised pro-resolving mediators of inflammation in inflammatory arthritis. | 27033423 |
| Inflammation, Arthritis | Altered Intercellular Communication | They promote resolution of inflammation and may contribute to the beneficial effects of n-3FA in patients with arthritis. | 27033423 |
| Pain Distress Question, Arthritis, Inflammation, SCAPULOPERONEAL MYOPATHY, X-LINKED DOMINANT | Altered Intercellular Communication | SPM are present in chronic knee effusions and although the levels are lower than in plasma, the association between synovial fluid RvE2 and reduced pain scores suggests that synthesis of SPM at the site of inflammation is a relevant mechanism by which n-3FA alleviate the symptoms of arthritis. | 27033423 |
| Gastrointestinal inflammation | Altered Intercellular Communication | Little is known about the mechanisms that cause persistent intestinal inflammation in these patients. | 27033429 |
| Inflammation, Fibrosis Assessment | Altered Intercellular Communication | Immunoglobulin G4-related disease (IgG4-RD) represents a group of disorders that share features of inflammation, plasma cell infiltrates, and fibrosis. | 27033871 |
| Cholangitis, Sclerosing, Inflammation, Cholestasis, Cicatrization | Altered Intercellular Communication | Sclerosing cholangitis is a disorder involving inflammation, scarring, and destruction of the bile ducts. | 27033871 |
| Cardiac sarcoidosis, Myocarditis, Atherosclerosis | Altered Intercellular Communication | Patients with cardiac sarcoidosis (CS) suffer from myocardial inflammation, but atherosclerosis is not infrequent in these patients. | 27035112 |
| Airway structure, ARCN1 gene, Chronic Obstructive Airway Disease | Altered Intercellular Communication | Chronic airway inflammation and airway remodeling are the major pathophysiological characteristics of chronic obstructive pulmonary disease (COPD). | 27035424 |
| vascular inflammations, Thrombosis, Cardiovascular Diseases | Altered Intercellular Communication | The function of platelets have extended way beyond the horizon of haemostasis and thrombosis, and are recognised as active participants in vascular inflammation, as well as in prothrombotic complications of cardiovascular diseases. | 27036108 |
| Inflammation, Primary malignant neoplasm | Altered Intercellular Communication | Visfatin is an adipocytokine involved in cellular metabolism, inflammation, and cancer. | 27036136 |
| Inflammation | Altered Intercellular Communication | Moreover, CD16-triggered cytokine production by CD56(dim) NK cells may contribute to systemic inflammation as seen in SP arthralgia and SP RA. | 27036380 |
| Inflammation, Atherosclerosis | Altered Intercellular Communication | Protein-Protein interaction analysis evidenced a network among differentially expressed proteins in which vitronectin seems to represent a potentially pivotal node among fibrinolysis, complement dependent immune responses and inflammation in accordance with a number of in vitro and in vivo evidences for a contributory role of these proteins to the development of diabetic atherosclerosis. | 27037039 |
| Have Autoimmune or Inflammatory Condition | Altered Intercellular Communication | Clinical and paraclinical criteria were used to blindly determine evidence for autoimmune inflammation in both groups. | 27037230 |
| Have Autoimmune or Inflammatory Condition, LGI1 protein, human | Altered Intercellular Communication | Evidence for autoimmune inflammation was present in 7 (28%) of the VGKC-positive patients lacking LGI1 and Caspr2, compared to 9 (18%) of the VGKC-negative controls (p = 0.38). | 27037230 |
| Encephalomyelitis, Have Autoimmune or Inflammatory Condition | Altered Intercellular Communication | Evidence for autoimmune inflammation was mainly found in patients with limbic encephalitis/encephalomyelitis (57%), but not in other clinical phenotypes (5%, p < 0.01). | 27037230 |
| Have Autoimmune or Inflammatory Condition | Altered Intercellular Communication | However, antibodies to Caspr2 could also be detected in patients with inconclusive low VGKC titer, while many VGKC-positive patients had no evidence for autoimmune inflammation. | 27037230 |
| Have Autoimmune or Inflammatory Condition, LGI1 protein, human | Altered Intercellular Communication | VGKC positivity in the absence of antibodies to LGI1 and Caspr2 is not a clear marker for autoimmune inflammation and seems not to contribute in clinical practice. | 27037230 |
| Have Autoimmune or Inflammatory Condition | Altered Intercellular Communication | No cutoff value for the VGKC titer was appropriate to discriminate between patients with and without autoimmune inflammation. | 27037230 |
| Inflammation, Psoriasis, Inflammatory dermatosis | Altered Intercellular Communication | Psoriasis is a common inflammatory skin disease, and inflammation may affect suicidal behaviour. | 27038335 |
| Granulomatous inflammation, Necrosis | Altered Intercellular Communication | Histological examination of spinal biopsy samples revealed lesions of necrosis, granulomatous inflammation and septate hyphae with acute-angle branching. | 27038797 |
| Inflammation | Altered Intercellular Communication | Recent findings suggest that increased visceral fat deposition is a modifier of inflammation. | 27038807 |
| Inflammation, Endothelial dysfunction, Atherosclerosis | Altered Intercellular Communication | They are associated with adverse clinical conditions such as atherosclerosis, endothelial dysfunction, inflammation and abnormal blood pressure variability. | 27039198 |
| Communicable Diseases, Inflammation | Altered Intercellular Communication | It is difficult to make a distinction between inflammation and infection. | 27039298 |
| Degenerative polyarthritis, Inflammation | Altered Intercellular Communication | Association between biomarkers of tissue inflammation and progression of osteoarthritis: evidence from the Rotterdam study cohort. | 27039382 |
| Gastrointestinal inflammation | Altered Intercellular Communication | Consumption of milk containing A1 b-casein was associated with increased gastrointestinal inflammation, worsening of PD3 symptoms, delayed transit, and decreased cognitive processing speed and accuracy. | 27039383 |
| Inflammatory abnormality of the eye | Altered Intercellular Communication | The ocular inflammation is usually temporary and resolves with topical ocular steroids. | 27039491 |
| Inflammation, Epithelial metaplasia | Altered Intercellular Communication | The histological features of AILI sought were lobule-based alveolar wall thickening (myxomatous or fibrous) with epithelial metaplasia and negligible inflammation. | 27040641 |
| Communicable Diseases, Inflammation, Infection | Altered Intercellular Communication | Different markers of inflammation and/or infection in joint fluid have been proposed for diagnosis of these infections. | 27040804 |
| Inflammation, Rheumatic Heart Disease | Altered Intercellular Communication | Pathohistological Evidence of Smoldering Inflammation in Rheumatic Heart Disease with Massive Left Atrial Calcification. | 27041159 |
| Adaptive Immunity, Liver damage, Chronic inflammation | Altered Intercellular Communication | This may be due to accumulated cellular damage, decreases in adaptive immunity, and chronic inflammation. | 27042933 |
| Inflammation, Chronic Kidney Diseases | Altered Intercellular Communication | GDF-15, iron, and inflammation in early chronic kidney disease among elderly patients. | 27043030 |
| Inflammation, Electrocardiogram: myocardial infarction (finding), Dental Plaque | Altered Intercellular Communication | p38 Mitogen-activated protein kinase (MAPK)-stimulated inflammation is implicated in atherogenesis, plaque destabilization, and maladaptive processes in myocardial infarction (MI). | 27043082 |
| Chronic Lymphocytic Leukemia | Altered Intercellular Communication | Biopsies of these nodules did not reveal the usual Th2 milieu of chronic lymphocytic leukemia but instead exhibited a Th1-rich lymphocytic infiltrate with resultant neutrophil and granulomatous inflammation. | 27043332 |
| Inflammation, Ulcerative Colitis | Altered Intercellular Communication | Colonoscopy, performed on the 40th day after termination of drug therapy, revealed diffuse inflammation in the distal aspect of the colon, with histologic findings consistent with ulcerative colitis. | 27043835 |
| Inflammation, Asthma | Altered Intercellular Communication | Detailed analysis of sputum and systemic inflammation in asthma phenotypes: are paucigranulocytic asthmatics really non-inflammatory? | 27044366 |
| Inflammation, Asthma, Inflammatory disorder | Altered Intercellular Communication | This study demonstrates that a significant eosinophilic inflammation is present across all categories of asthma, and that paucigranulocytic asthma may be seen as a low grade inflammatory disease. | 27044366 |
| Inflammation | Altered Intercellular Communication | Lifetime very high LTPA is associated with increased lowgrade inflammation and may, therefore, exert an atherogenic effect. | 27044376 |
| Inflammation, Primary malignant neoplasm, Cardiovascular Diseases, Hepatobiliary Disorder, Obesity, Diabetes Mellitus, Non-Insulin-Dependent | Altered Intercellular Communication | Obesity is a global health problem presenting serious risk of disease fuelled by chronic inflammation, including type 2 diabetes mellitus, cardiovascular disease, liver disease and cancer. | 27046081 |
| Inflammation | Altered Intercellular Communication | We propose that chemokine-mediated trafficking of pro-inflammatory cells to the omentum and liver contributes to local and subsequent systemic inflammation. | 27046081 |
| Inflammation, Primary malignant neoplasm, Gastroesophageal Junction Adenocarcinoma, Obesity | Altered Intercellular Communication | Oesophagogastric adenocarcinoma (OAC) is an exemplar model of obesity and inflammation driven cancer. | 27046081 |
| Inflammation, Leucocytic infiltrate, Omentum, Obesity, Obesity-Associated Insulin Resistance | Altered Intercellular Communication | These novel data suggest that chemokine receptor antagonism may have therapeutic potential to reduce inflammatory T cell infiltration to the omentum and liver and in doing so, may ameliorate pathological inflammation in obesity and obesity-associated cancer. | 27046081 |
| Airway structure, ARCN1 gene, Chronic Obstructive Airway Disease | Altered Intercellular Communication | Mechanisms driving persistent airway inflammation in chronic obstructive pulmonary disease (COPD) are incompletely understood. | 27046438 |
| ARCN1 gene, Airway structure | Altered Intercellular Communication | As secretory immunoglobulin A (SIgA) deficiency in small airways has been reported in COPD patients, we hypothesized that immunobarrier dysfunction resulting from reduced SIgA contributes to chronic airway inflammation and disease progression. | 27046438 |
| Inflammation | Altered Intercellular Communication | The pathologic report revealed chronic inflammation due to the presence of a foreign body. | 27048126 |
| Asthma | Altered Intercellular Communication | In children with asthma, web-based monitoring and inflammation-driven therapy may lead to improved asthma control and reduction in medications. | 27048197 |
| Inflammation | Altered Intercellular Communication | The inflammation in gastric mucosa was analyzed with histology. | 27048452 |
| Inflammation | Altered Intercellular Communication | The H. pylori-infected gastric mucosa had more severe inflammation than uninfected samples. | 27048452 |
| Inflammatory abnormality of the eye | Altered Intercellular Communication | Chronic recurrent or persisting ocular inflammation was present in 15 of 19 patients (78.9%). | 27048999 |
| Obesity | Altered Intercellular Communication | Its etiology is unknown but in analogy to central obesity, chronic low-level inflammation in adipose tissue has been suggested. | 27049087 |
| ARCN1 gene, Inflammation, Chronic Obstructive Airway Disease | Altered Intercellular Communication | Chronic Obstructive Pulmonary Disease (COPD) is characterised by increased neutrophilic inflammation. | 27049289 |
| Inflammation, Cirrhotic | Altered Intercellular Communication | This study did not find indications for oxidative stress and low-grade inflammation in the small and large intestine of stable compensated cirrhotic patients. | 27049494 |
| Inflammation, Cholestasis | Altered Intercellular Communication | Ursodeoxycholic acid (UDCA) is the first choice medication for most cholestatic hepatopathies, due to its capability to counteract inflammation and bile-acid-induced liver damage, two common features in cholestasis. | 27049500 |
| Stomach Carcinoma | Altered Intercellular Communication | The interleukin-6 (IL-6)/JAK/STAT3 signaling pathway plays a central role in inflammation-mediated cancers, including gastric cancer (GCa). | 27049718 |
| Inflammation, Graft dysfunction, Hyperglycemia | Altered Intercellular Communication | Severe inflammation leads to increased graft immunogenicity and risk of graft dysfunction; while acute hyperglycemia aggravates the inflammatory response and increases the risk of morbidity and mortality. | 27050068 |
| Refractory anemias, Inflammation, Fibrosis Assessment | Altered Intercellular Communication | In active RA, myocardial T1 relaxation times are prolonged suggesting diffuse inflammation or fibrosis. | 27050802 |
| Inflammation | Altered Intercellular Communication | Local myocardial scars and inflammation, visible as LGE, are also common, as are impairments of LV systo-diastolic function. | 27050802 |
| Refractory anemias, Inflammation, Rheumatoid Arthritis, Disease | Altered Intercellular Communication | To investigate the presence of biomechanical abnormalities and ultrasound (US)-detected inflammation and damage in low disease or remission status rheumatoid arthritis (RA) patients with foot complaints. | 27050868 |
| Inflammation, Acute onset pain, Postsurgical Stage I | Altered Intercellular Communication | Poor acute pain control and inflammation are important risk factors for Persistent Postsurgical Pain (PPSP). | 27051077 |
| Inflammation, Atherosclerosis | Altered Intercellular Communication | Linking CD11b (+) Dendritic Cells and Natural Killer T Cells to Plaque Inflammation in Atherosclerosis. | 27051078 |
| Inflammation, Atherosclerosis | Altered Intercellular Communication | To investigate whether the dynamics of leukocyte (sub)populations could be predictive for plaque inflammation during atherosclerosis, we analyzed innate and adaptive immune cell distributions in blood, plaques, and lymphoid tissue reservoirs in apolipoprotein E-deficient (ApoE(-/-)) mice and in blood and plaques from patients undergoing endarterectomy. | 27051078 |
| Inflammation, Dental Plaque | Altered Intercellular Communication | Secondly, a strong inverse correlation was observed between CD11b(+) cDC or natural killer T (NKT) cells in blood and markers of inflammation in the plaque (including CD3, T-bet, CCR5, and CCR7). | 27051078 |
| Inflammation, Obesity | Altered Intercellular Communication | Obesity stimulates chronic inflammation in adipose tissue, which is associated with insulin resistance, although the underlying mechanism remains largely unknown. | 27051864 |
| Intradermal Route of Drug Administration, Inflammation, Anemia | Altered Intercellular Communication | Correction for inflammation based on CRP and AGP did not markedly change the overall prevalence of ID and ID anemia. | 27052301 |
| Inflammation, Diabetes Mellitus, Hepatic Complication | Altered Intercellular Communication | Intake of polyphenols and polyphenol-rich fruit extracts has been shown to reduce markers of inflammation, diabetes, and hepatic complications that result from the consumption of a high-fat (HF) diet. | 27052533 |
| Inflammation | Altered Intercellular Communication | However, training at high external load also increased anti-inflammatory IL-1ra in male participants, which might be beneficial in combating low-grade inflammation. | 27052561 |
| Inflammation, Colitis | Altered Intercellular Communication | Hematoxylin and eosin stained tissue sections from colonic biopsies were classified histologically as normal or colitis (active/inactive), and scored for the degree of inflammation present (0-3, inactive/absent to severe). | 27053850 |
| Inflammatory Bowel Diseases, Inflammation, Crohn Disease | Altered Intercellular Communication | Histologic inflammation was significantly higher in visually diseased mucosa from IBD patients (1.95 +- 0.25) than in normal-appearing mucosa from control patients (0.25 +- 0.08, P < 0.01) and from IBD patients (0.65 +- 0.36, P < 0.05) and correlated inversely with VDR expression in visually diseased colonic tissue from IBD patients (r = -0.44, P < 0.05) and from IBD patients with Crohn's disease (r = -0.69, P < 0.05), but not in normal-appearing colonic tissue from control patients or IBD patients. | 27053850 |
| Vitreous inflammatory cells | Altered Intercellular Communication | At baseline, anterior chamber and vitreous inflammation were present in 6 (50%) and 7 (58.3%) of the eyes. | 27054359 |
| Vitreous inflammatory cells | Altered Intercellular Communication | Besides reduction anterior chamber and vitreous inflammation, we observed a reduction of OCT values, from 330.4+-58.5 mm at the onset of the biological agent to 273+-50 mm at month 12 (p=0.06). | 27054359 |
| Ruptured behavior, Cyst, Inflammation, Pain Distress Question | Altered Intercellular Communication | If ruptured, an inflammatory response can occur in the area surrounding the cyst, which can also induce pain, while the locations around intracranial and intraspinal extensions have a higher risk of inflammation; therefore, a definitive diagnosis is important. | 27054417 |
| Inflammation, Hemorrhage, Solitary diverticulum of cecum, Perforation (observation) | Altered Intercellular Communication | Solitary cecum diverticulum is a benign formation, but it can be complicated with inflammation, perforation and bleeding. | 27054646 |
| Inflammation, Atrial Fibrillation by ECG Finding | Altered Intercellular Communication | Systemic inflammation plays an important role in the pathogenesis of atrial fibrillation (AF). | 27055157 |
| Neoplasms, Necrosis | Altered Intercellular Communication | Inflammation of the liver occurs after treatment as a result of radiation doses from the ion beam, and the tumor reaches a state of necrosis. | 27055451 |
| Inflammation | Altered Intercellular Communication | This study shows for the first time that sphingolipids and particularly glucosylceramide are associated with and are possible inducers of plaque inflammation and instability, pointing to sphingolipid metabolic pathways as possible novel therapeutic targets. | 27055903 |
| Inflammation | Altered Intercellular Communication | High MBL may contribute to low cIMT, whereas the association of MBL with low-grade inflammation was nonlinear. | 27055907 |
| Inflammation, Metabolic Diseases, Data types - Address | Altered Intercellular Communication | FABP5 is a biomarker of adiposity-associated metabolic derangements that include AD thus underscoring the concomitant presence of inflammation. | 27055964 |
| ARCN1 gene, Inflammation, Hypoalbuminemia | Altered Intercellular Communication | We demonstrated that poor periodontal health was associated with hypoalbuminemia, suggesting poor nutritional status and inflammation in COPD. | 27056058 |
| Inflammation, Primary malignant neoplasm, Demographics Domain, Atherosclerosis, Diabetes Mellitus | Altered Intercellular Communication | Growth differentiation factor 15 (GDF-15) is a member of the transforming growth factor ss family and has been associated with inflammation, cancer, aging, diabetes mellitus (DM) and atherosclerosis. | 27056183 |
| Hyperglycemia, Inflammation, Chronic Kidney Diseases | Altered Intercellular Communication | In patients with CAD undergoing PCI with stent implantation, GDF-15 is determined by advanced age, acute and chronic hyperglycemia, inflammation and CKD. | 27056183 |
| Anemia, Syndrome | Altered Intercellular Communication | Furthermore, low T3 syndrome is closely associated with both malnutrition-inflammation complex syndrome (MICS) and anemia. | 27056188 |
| ARCN1 gene, Chronic Obstructive Airway Disease | Altered Intercellular Communication | Chronic obstructive pulmonary disease (COPD) is a nonreversible inflammatory condition of the lungs. | 27056359 |
| Hyperplasia, Parathyroid Adenoma, Hyperparathyroidism, Primary, Malignant Neoplasms | Altered Intercellular Communication | Primary hyperparathyroidism is a rare disease characterized by excessive secretion of parathyroid hormone from parathyroid adenoma, hyperplasia, or malignancy. | 27056365 |
| Chorioretinitis, Glaucoma, CTCAE | Altered Intercellular Communication | Rare causes of neovascular glaucoma are multiple and are due to VEGF synthesis associated with chorioretinal inflammations or degenerations. | 27057253 |
| Crohn Disease, Inflammatory disorder | Altered Intercellular Communication | Can Dynamic Contrast-Enhanced MRI (DCE-MRI) and Diffusion-Weighted MRI (DW-MRI) Evaluate Inflammation Disease: A Preliminary Study of Crohn's Disease. | 27057860 |
| Inflammation, Neoplasms | Altered Intercellular Communication | Systemic inflammation and immune response were associated with prognosis of tumors. | 27057867 |
| Mycobacterium Infections, Lymphoid hyperplasia, Inflammation, Carcinoma of lung | Altered Intercellular Communication | Lung cancer was diagnosed in 12 lesions, nontuberculous mycobacterial disease in 1 lesion, lymphoid hyperplasia in 1 lesion, and inflammation in 3 lesions. | 27058710 |
| Inflammation | Altered Intercellular Communication | It has been suggested that chronic inflammation may be involved in the pathogenesis of frailty. | 27058767 |
| Nerve palsy, Inflammation, Seizures, Neuroleptic Malignant Syndrome, Cerebral Hemorrhage, malignant syndrome nos, Meningoencephalitis | Altered Intercellular Communication | Of the 31 patients with altered sensorium, 15 (40%) had meningoencephalitis, three (8%) had seizures, two (5%) had cerebral haemorrhages, one (2%) had a presentation likened to neuroleptic malignant syndrome (NMS) and one (2%) had a 6th nerve palsy with inflammation of the right cavernous sinus. | 27059055 |
| Inflammation Mediators, Neuropathy | Altered Intercellular Communication | Many cases of CTP are thought to be associated with neuropathy and recent data suggest an inflammation-mediated process is more common among patients with CTP. | 27059628 |
| Refractory anemias, Inflammation | Altered Intercellular Communication | The differential citrullinated proteins identified in RA SFs suggested potential autoantigens were targeted for ACPAs response and might contribute to the induction and perpetuation of complement activation and joint inflammation in RA. | 27060082 |
| Inflammation | Altered Intercellular Communication | In the false-positive cases, the number of tumor-infiltrating inflammatory cells at the primary skin site was highest among the four groups, suggesting that inflammation contributed to the false-positive uptake of FDG. | 27060693 |
| Inflammation, Neutrophil Infiltration | Altered Intercellular Communication | Neutrophil elastase plays an important role in skin inflammation induced by neutrophil infiltration. | 27060697 |
| Fibrosis Assessment, Hepatic inflammation, Hypertension, CTCAE, Liver Cirrhosis | Altered Intercellular Communication | To investigate whether the combination of sCD163 as a hepatic inflammation marker and the fibrosis markers of the Enhanced Liver Fibrosis score (ELF) can predict portal hypertension in patients with cirrhosis. | 27061098 |
| Refractory anemias, Inflammation | Altered Intercellular Communication | Hence, impaired CBG-mediated delivery of endogenous cortisol may perpetuate chronic inflammation in RA. | 27061835 |
| Inflammation, Hemochromatosis | Altered Intercellular Communication | The associations were not explained by inflammation and haemochromatosis genotype was not associated with QT interval length. | 27062493 |
| Inflammation, Hemochromatosis | Altered Intercellular Communication | In conclusion, increased iron stores, independent of haemochromatosis genotype and inflammation, are associated with prolongation of the QTc interval in men. | 27062493 |
| Acute Kidney Injury, CTCAE, Inflammation, Kidney Failure, Acute | Altered Intercellular Communication | Plasma Neutrophil Gelatinase Associated-Lipocalin (NGAL) is a promising biomarker for acute kidney injury (AKI) detection; however, it is also increased with inflammation and few studies have been conducted in non-Caucasian populations and/or in developing economies. | 27062515 |
| Inflammation, glycation, diabetic | Altered Intercellular Communication | Pioglitazone alleviates inflammation in diabetic mice fed a high-fat diet via inhibiting advanced glycation end-product-induced classical macrophage activation. | 27062545 |
| Inflammation, diabetic | Altered Intercellular Communication | Classically activated macrophages (M1) are associated with inflammation in diabetic patients. | 27062545 |
| Inflammation, Diabetes Mellitus | Altered Intercellular Communication | Inflammation is a known risk factor in diabetes. | 27062545 |
| Inflammation, glycation, diabetic | Altered Intercellular Communication | The present study tested the hypothesis that pioglitazone (PIO) alleviates inflammation in diabetic mice fed a high-fat diet by inhibiting advanced glycation end-product (AGE)-induced classical macrophage activation. | 27062545 |
| Inflammation, Diabetes Mellitus | Altered Intercellular Communication | Therefore, we conclude that PIO blocks classical activation of macrophages and attenuates inflammation in mouse models of diabetes. | 27062545 |
| Inflammation, Primary malignant neoplasm | Altered Intercellular Communication | Inflammation plays a pivotal role in cancer development and progression. | 27062567 |
| Inflammation, Carcinogenesis | Altered Intercellular Communication | HMGB1 is an extracellular signalling molecule that plays a role both in inflammation and carcinogenesis. | 27062570 |
| ARCN1 gene, Respiratory physiology, Chronic Obstructive Airway Disease, Inflammation | Altered Intercellular Communication | Chronic obstructive pulmonary disease (COPD) is characterized by progressive loss of lung function and local and systemic inflammation, in which CD8+ T-cells are believed to play a key role. | 27064034 |
| ARCN1 gene, Inflammation | Altered Intercellular Communication | Peripheral Tc17 cells are increased and more likely to convert to Tc17/IFN-g cells in COPD, suggesting that Tc17 cell plasticity may be involved in persistent inflammation of the disease. | 27064034 |
| Inflammation, Diabetic Foot, Ulcer | Altered Intercellular Communication | To verify the reliability and validity of FLIR ONE, a device connected to a smartphone, for the assessment of inflammation based on relative temperature increase compared with the thermography routinely used in pressure ulcer (PU) and diabetic foot assessment. | 27064366 |
| Inflammation, Diabetic Foot | Altered Intercellular Communication | This pilot study suggests that FLIR ONE can work as an alternative device for assessing subclinical inflammation in PUs and the diabetic foot in clinical settings. | 27064366 |
| Inflammation, Non-Small Cell Lung Carcinoma, Necrotizing | Altered Intercellular Communication | Does Every Necrotizing Granulomatous Inflammation Identified by NSCLC Resection Material Require Treatment? | 27064420 |
| Necrotizing granulomatous inflammation, Non-Small Cell Lung Carcinoma | Altered Intercellular Communication | Patients who had NSCLC surgery between 2009 and 2013 were included and patient records were reviewed for the presence of necrotizing granulomatous inflammation (NGI) in resected specimens. | 27064420 |
| Granulomatosis, Granulomatous inflammation, Necrotizing vasculitis, Systemic Vasculitis | Altered Intercellular Communication | Granulomatosis with polyangiitis (GPA), extremely rare in children, is a disease characterized by granulomatous inflammation and necrotizing vasculitis that involves medium and small vessels. | 27066798 |
| RECIL MR, Sinusitis | Altered Intercellular Communication | MR in the last episode indicated bilateral sphenoid sinus inflammation adjacent to the left optical nerve. | 27066798 |
| Refractory anemias, Inflammation | Altered Intercellular Communication | RA and CVD both have inflammation as part of the underlying biology. | 27067270 |
| Refractory anemias, Inflammation | Altered Intercellular Communication | In RA, greater GlycA associated with disease activity (DAS-28; RDAS-28 = 0.5) and inflammation (RESR = 0.7, RhsCRP = 0.7, RIL-6 = 0.3: P < 0.05 for all); in BMI-matched controls, these inflammatory associations were absent or weaker (hsCRP), but GlycA was related to IL-18 (RhsCRP = 0.3, RIL-18 = 0.4: P < 0.05). | 27067270 |
| Celiac Disease, Malabsorption Syndrome, Atrophic | Altered Intercellular Communication | Coeliac disease (CD) is a gluten-induced autoimmune inflammation of small bowel villi, leading to atrophy and malabsorption. | 27067921 |
| Inflammation, Vasculitis, CTCAE | Altered Intercellular Communication | (18)F-FDG PET/CT has a promising role in grading inflammation in patients with large arteries vasculitis. | 27068039 |
| Inflammation, Chronic Kidney Diseases | Altered Intercellular Communication | Future studies should focus on social and genetic determinants of inflammation and their association with CKD in this ethnicity. | 27068267 |
| Inflammation, Malignant Pleural Mesothelioma, 1-methyl-1-piperidinomethane sulfonate | Altered Intercellular Communication | Inflammation plays a role in malignant pleural mesothelioma (MPM) prognosis and symptoms. | 27068290 |
| Inflammation, Carcinogenesis, Ovarian Carcinoma | Altered Intercellular Communication | Our data suggest that TNF-a expression in ovarian carcinoma varies by histologic subtype and provides some support for the role of inflammation in ovarian carcinogenesis. | 27068525 |
| Barrett Esophagus, Acid reflux, "Barretts Adenocarcinoma | Altered Intercellular Communication | Barrett's esophagus (BE) caused by gastroesophageal reflux is a major risk factor of Barrett's esophageal adenocarcinoma (BEA), an inflammation-related cancer. | 27069317 |
| Tissue damage, Inflammation | Altered Intercellular Communication | Chronic inflammation and following tissue damage may activate progenitor cells under reactive oxygen/nitrogen species-rich environment. | 27069317 |
| Primary malignant neoplasm, Inflammation Mediators | Altered Intercellular Communication | Our results suggest that BE columnar epithelial cells with CD133 expression in apical surface undergo inflammation-mediated DNA damage, and mutated cells acquire the property of cancer stem cells with cytoplasmic CD133 expression. | 27069317 |
| Inflammation, Platelet aggregation test result | Altered Intercellular Communication | However, mediators of inflammation (C-reactive protein, Txnip) did not correlate significantly with LASp nor did extent of ADP-induced platelet aggregation or platelet NO response. | 27069318 |
| Inflammation, Platelet aggregation | Altered Intercellular Communication | These results suggest that the thrombogenic risk associated with LA stasis is independent of secondary effects on platelet aggregability or inflammation. | 27069318 |
| Intraocular inflammation, Uveitis | Altered Intercellular Communication | Uveitis reactivation was ascribed to clinically quiescent patients who developed reactivation of intraocular inflammation within 6 months. | 27070110 |
| Inflammation, Uveitis | Altered Intercellular Communication | A total of 606 consecutive patients with uveitis were screened for etiologies and classified according to the anatomic sites of inflammation. | 27070829 |
| Inflammation | Altered Intercellular Communication | However, little is known about the biomarker role of telomere length (TL) for predicting inflammation and glucose alterations. | 27071798 |
| Obesity | Altered Intercellular Communication | Relationship Between Measures of Adiposity, Arterial Inflammation, and Subsequent Cardiovascular Events. | 27072302 |
| Arteritis | Altered Intercellular Communication | VAT volume (r=0.290; P<0.001) and VAT/SAT ratio (r=0.208; P<0.001) were positively correlated with arterial inflammation. | 27072302 |
| Inflammation | Altered Intercellular Communication | The findings suggest that arterial inflammation may explain some of the CVD risk associated with adiposity. | 27072302 |
| Refractory anemias, Arthritis | Altered Intercellular Communication | Ultrasound-detected joint inflammation and B cell count: related variables for rituximab-treated RA patients? | 27072348 |
| Inflammation | Altered Intercellular Communication | The age-dependent increase in CSF-[KYNA] may reflect a compensatory response to age-related inflammation, which may be deficient in KATII-TT-carriers. | 27072370 |
| Inflammation | Altered Intercellular Communication | The lesion was biopsied in the outpatient setting and demonstrated ulceration with marked acute and chronic inflammation in addition to granulation tissue. | 27072732 |
| Inflammation, Apocrine sweat gland structure, Chronic disease | Altered Intercellular Communication | Fox-Fordyce disease (FFD) is a rare chronic disorder characterised by persistent inflammation because of the obstruction of apocrine sweat glands, which is a key factor of pathogenesis. | 27072751 |
| Inflammation, Stenosis of lacrimal punctum | Altered Intercellular Communication | Recent studies have highlighted inflammation in punctoplasty specimens in patients with punctal stenosis. | 27073206 |
| Cerebrovascular accident | Altered Intercellular Communication | Obstructive Sleep Apnea in Acute Stroke: A Role for Systemic Inflammation. | 27073238 |
| Inflammation, Osage language, Thrombophilia, Cerebrovascular accident | Altered Intercellular Communication | We prospectively evaluated clinical characteristics and laboratory markers of inflammation and coagulability associated with OSA severity during the acute post stroke period. | 27073238 |
| Inflammation, diabetic | Altered Intercellular Communication | Insulin Resistance in Relation to Lipids and Inflammation in Type-2 Diabetic Patients and Non-Diabetic People. | 27073920 |
| Airway structure, Asthma, Bronchial Hyperreactivity | Altered Intercellular Communication | Previous studies on association between level of asthma control, markers of airway inflammation and the degree of bronchial hyperresponsiveness (BHR) have yielded conflicting results. | 27074221 |
| Inflammation, Fatty degeneration | Altered Intercellular Communication | Serum miR-122 levels (calibrated relative to the median levels of patients) partly affected severity of steatosis, ballooning, lobular inflammation, and stage. | 27074850 |
| Fibrosis Assessment, Hepatitis | Altered Intercellular Communication | However, whereas VB-201 inhibited the development of fibrosis and, to some extent, liver inflammation, VB-703 significantly lessened both liver inflammation and fibrosis. | 27074921 |
| Inflammation, Blood Coagulation Disorders | Altered Intercellular Communication | Blood examination showed inflammation reaction and slight disseminated intravascular coagulopathy. | 27075151 |
| Inflammation, Acute appendicitis NOS (disorder) | Altered Intercellular Communication | Evaluation of mediators of oxidative stress and inflammation in patients with acute appendicitis. | 27075266 |
| Inflammation, Primary malignant neoplasm | Altered Intercellular Communication | Plasma variation and reproducibility of oxidized LDL-cholesterol and low-grade inflammation biomarkers among participants of the Malmo Diet and Cancer cohort. | 27075407 |
| Inflammation, Hypertriglyceridemia, Obesity | Altered Intercellular Communication | The Association Between Obesity and Cognitive Function in Older Persons: How Much Is Mediated by Inflammation, Fasting Plasma Glucose, and Hypertriglyceridemia? | 27075896 |
| Inflammation, Hypertriglyceridemia, Obesity | Altered Intercellular Communication | There is a weak positive association between obesity and cognitive performance in older persons, which is partially antagonized by inflammation and elevated fasting plasma glucose, but not hypertriglyceridemia. | 27075896 |
| Gastrointestinal inflammation, Ulcerative Colitis | Altered Intercellular Communication | Role of noninvasive biomarkers of intestinal inflammation in evaluation of patients with UC is not well understood. | 27076259 |
| Inflammatory disease of mucous membrane | Altered Intercellular Communication | Although it is well-recognized that SJS/TEN is associated with severe ocular mucosal inflammation and cicatrizing, potentially blinding, sequelae, this association has not been described in relation to other SCARs. | 27078005 |
| Inflammatory abnormality of the eye | Altered Intercellular Communication | The ocular surface inflammation was addressed with intensive topical corticosteroid ointment. | 27078005 |
| Inflammatory disease of mucous membrane | Altered Intercellular Communication | The development of severe ocular surface mucosal inflammation and denudation with cicatrizing sequelae in a patient carrying a diagnosis of DRESS/DIHS has diagnostic and therapeutic implications for the ophthalmologist. | 27078005 |
| Parkinson Disease, Inflammation | Altered Intercellular Communication | The levels of IL-8 and TNF-a were significantly lower in serum of Parkinson's disease patients, which suggested that inflammatory factors might exert their effect and more specifically, inflammation might play crucial role in Parkinson's disease. | 27078697 |
| Inflammation, Atherosclerosis | Altered Intercellular Communication | Autophagy dysfunction in mouse atherosclerosis models has been associated with increased lipid accumulation, apoptosis and inflammation. | 27079462 |
| Granulomatous inflammation | Altered Intercellular Communication | These findings on LSFG and ICGA clearly demonstrated subclinical involvement as well as post-treatment improvement of choroidal circulation impairment due to granulomatous inflammation in eyes with the anterior recurrence of VKH disease. | 27079805 |
| Meningioma | Altered Intercellular Communication | Meningiomas can present during pregnancy as the result of hormonal as well as fluid changes. | 27080233 |
| Inflammation, Toxic effect, Communicable Diseases, Leukopenia, Anaphylactoid Reaction | Altered Intercellular Communication | Subjects will receive a 2- to 6-week course of anakinra by daily subcutaneous injection and will be assessed for resolution of inflammation and dose limiting toxicities (leukopenia, anaphylactoid reaction, or severe infection). | 27080929 |
| Middle Age, Inflammation, Cardiovascular Diseases | Altered Intercellular Communication | In middle-age group, a multivariate-forward logistic regression analysis showed that male sex (2.169 [1.029, 4.574], P = 0.042), inflammation (4.167 [2.043, 8.498], P < 0.001), cardiovascular disease (2.92 [1.019, 8.402], P = 0.046), serum creatinine level (0.639 [0.538, 0.758], P < 0.001), and cholesterol level (0.984 [0.975, 0.993], P = 0.001) were associated with serum albumin level <3.6 g/dL. | 27082584 |
| Inflammation, Arteriovenous fistula, Hepatitis C | Altered Intercellular Communication | Hepatitis C virus infection (1.911 [1.186, 3.077], P = 0.008), HDF (2.143 [1.298, 3.540], P = 0.003), inflammation (2.309 [1.549, 3.440], P < 0.001), use of arterio-venous fistula (0.518 [0.327, 0.820], P = 0.005), Kt/V (0.395 [0.193, 0.809], P = 0.011), nonanuria (0.542 [0.337, 0.870], P = 0.011), serum creatinine level (0.744 [0.669, 0.828], P < 0.001), and cholesterol level (0.993 [0.987, 0.998], P = 0.013) were associated with serum albumin level <4 g/dL. | 27082584 |
| Airway structure, ARCN1 gene, Asthma | Altered Intercellular Communication | Exhaled nitric oxide (eNO) has been documented as a marker of airway inflammation in asthma, but not in COPD. | 27082615 |
| ARCN1 gene, Inflammation, Asthma | Altered Intercellular Communication | We conclude that asthma with FAO may represent residual inflammation in the airways, while dynamic hyperinflation in COPD may retain NO in the distal airspace. | 27082615 |
| ARCN1 gene | Altered Intercellular Communication | In this study, we sought to differentiate an IL-1b-associated sputum signature from other inflammation-associated COPD phenotypes. | 27083436 |
| Inflammation | Altered Intercellular Communication | Sputum IL-1b levels showed no significant association (p > 0.05, spearman) with known markers of other major COPD inflammation phenotypes. | 27083436 |
| Tissue damage, Inflammation, Organ Dysfunction Scores | Altered Intercellular Communication | Tissue damage volume predicts organ dysfunction and inflammation after injury. | 27083966 |
| Multiple Organ Failure, Inflammation, Systemic Inflammatory Response Syndrome | Altered Intercellular Communication | Multiply injured patients (MIPs) are at risk to develop multiple-organ failure (MOF) and prolonged systemic inflammation response syndrome (SIRS). | 27083966 |
| Inflammation, Squamous cell carcinoma, Malignant Neoplasms | Altered Intercellular Communication | Squamous cell carcinomas are malignant tumours of epithelial origin that can appear on sites subjected to chronic inflammation after a period of several years. | 27083971 |
| Inflammation, Juvenile rheumatoid arthritis, Uveitis | Altered Intercellular Communication | To describe the clinical and visual outcomes of juvenile idiopathic arthritis (JIA)-associated uveitis in adults and to examine risk factors for ongoing inflammation in adulthood. | 27084082 |
| Cataract, Inflammation | Altered Intercellular Communication | The presence of posterior synechiae, hypotony, cataract at presentation, and a history of cataract surgery prior to presentation were predictive of ongoing inflammation in adulthood in univariate analysis. | 27084082 |
| Inflammation, Visual Impairment, Complication Aspects, Uveitis | Altered Intercellular Communication | JIA-associated uveitis may be associated with ongoing inflammation, ocular complications, and severe visual impairment in adulthood. | 27084082 |
| Inflammation, Peripheral demyelinating neuropathy, Edema | Altered Intercellular Communication | Sonography of peripheral nerves can depict alteration of nerve sizes that could reflect inflammation and edema in inflammatory and demyelinating neuropathies. | 27084237 |
| Arterial Stiffness, Inflammation, Metabolic Diseases | Altered Intercellular Communication | The mechanisms linking air pollution and cardio-metabolic disorders may be associated with the increased systemic inflammation and oxidative stress, reduced insulin sensitivity and elevated arterial stiffness and blood pressure. | 27084335 |
| Inflammation, Myocarditis, CTCAE 5.0 | Altered Intercellular Communication | Acute myocarditis in its arrhythmic phenotype is probably characterized by a significant inflammation of conduction tissue. | 27084370 |
| Inflammation, Inflammatory disorder | Altered Intercellular Communication | Oral lichen planus (OLP) is a common T-cell-dominated oral chronic inflammatory disease occurring in periods of remission, quiescence, activity with pronounced inflammation, and acute ulceration. | 27084447 |
| Inflammation | Altered Intercellular Communication | These findings suggest that inflammation may be important for understanding mortality disparities by socioeconomic status. | 27085072 |
| Inflammation, Perforation (observation), Peritonitis | Altered Intercellular Communication | In patients with perforation, absence of CT findings suggestive of surrounding inflammation or peritonitis would help in choosing non-surgical management. | 27085213 |
| Pancreatitis, Acute, Inflammation | Altered Intercellular Communication | In this study, we show that B10 cells can inhibit inflammation of severe acute pancreatitis (SAP). | 27085321 |
| Inflammation, Cardiac complication | Altered Intercellular Communication | Gender difference in obesity-associated cardiovascular complication could be derived from divergent chronic inflammation. | 27086574 |
| Inflammation | Altered Intercellular Communication | In conclusion, Innate signals were differentially expressed in male and female adipose tissues, suggesting that the depot- and gender-specific signals could be related to gender difference in chronic inflammation. | 27086574 |
| Inflammation, Structure of right colic lymph node, Gallbladder | Altered Intercellular Communication | Eosinophilic inflammation was present through this rigid wall of the descending duodenum, accompanied by perienteric inflammation, which infiltrated the anterior pararenal space, gall bladder, and right colic flexure. | 27086704 |
| Inflammation, Primary malignant neoplasm | Altered Intercellular Communication | Thus, in order to prevent cancer from developing, appropriate medical therapy aiming not only to relieve the clinical symptoms, but also to suppress chronic inflammation appears to be necessary. | 27086804 |
| Inflammation | Altered Intercellular Communication | In patients without complete resolution of mucosal inflammation, careful surveillance colonoscopy should be initiated in the early phase. | 27086804 |
| Inflammation | Altered Intercellular Communication | This case suggests the possibility that eosinophilic inflammation can occur concomitantly in the central airway and distal airway. | 27086960 |
| Cessation of life, Inflammation | Altered Intercellular Communication | The objective of this study is to characterize the cell death and cell survival response of the prostatic epithelium in response to inflammation. | 27088546 |
| Inflammation, Psoriasis | Altered Intercellular Communication | Meanwhile, the expression of IL-8 significantly decreases with clinically more severe psoriasis, perhaps making these factors candidate prognostic factors for psoriatic inflammation. | 27088930 |
| Inflammation, Arthritis | Altered Intercellular Communication | Sclerostin effectively blocked TNFa- but not interleukin-1-induced activation of p38, a key step in arthritis development, pointing to a previously unrealized protective role of sclerostin in TNF-mediated chronic inflammation. | 27089204 |
| Refractory anemias, Inflammatory | Altered Intercellular Communication | The possibility of anti-sclerostin antibody treatment worsening clinical RA outcome under chronic TNFa-dependent inflammatory conditions in mice means that caution should be taken both when considering such treatment for inflammatory bone loss in RA and when using anti-sclerostin antibodies in patients with TNFa-dependent comorbidities. | 27089204 |
| Inflammation, Cardiovascular Diseases | Altered Intercellular Communication | Recently, lymphocyte-to-monocyte ratio (LMR) has emerged as a new indirect marker of inflammation which is associated with adverse outcomes in oncology and cardiovascular diseases. | 27089433 |
| Inflammation, Asthma, Respiratory Hypersensitivity | Altered Intercellular Communication | A semisynthetic diterpenoid lactone inhibits NF-kB signalling to ameliorate inflammation and airway hyperresponsiveness in a mouse asthma model. | 27089844 |
| Inflammation, Asthma, Respiratory Hypersensitivity | Altered Intercellular Communication | SRS27 is the first known DDAG analogue effective in ameliorating inflammation and airway hyperresponsiveness in the ovalbumin-induced mouse asthma model. | 27089844 |
| Inflammation, Chronic heart failure, Congestive heart failure | Altered Intercellular Communication | Immunity and inflammation processes are known to be of central importance in chronic heart failure (CHF). | 27090038 |
| Inflammation, Tauopathies, Dental Plaque, Trauma, Nervous System | Altered Intercellular Communication | RGNs are areas of concentrated neuronal injury, inflammation, and tauopathy and display unique features around b-amyloid plaque types. | 27090093 |
| Data types - Address | Altered Intercellular Communication | Leptin did not seem to be associated with IgE-mediated inflammation in AD. | 27090367 |
| Sleep Apnea, Obstructive | Altered Intercellular Communication | Oxidative Stress and Inflammation Differentially Elevated in Objective Versus Habitual Subjective Reduced Sleep Duration in Obstructive Sleep Apnea. | 27091532 |
| Inflammation | Altered Intercellular Communication | We postulate that oxidative stress and systemic inflammation biomarkers will be elevated in relation to short-term and long-term sleep duration reduction. | 27091532 |
| Inflammation, Obesity, Osage language | Altered Intercellular Communication | Even after consideration of obesity and OSA severity, inverse significant findings were observed such that reduced PSG-TST was associated with elevated MPO levels and SR-HSD with ox-LDL, suggesting differential up-regulation of oxidative stress and pathways of inflammation in acute versus chronic sleep curtailment. | 27091532 |
| Fever, CTCAE, Allergy - Charge Type Reason, Dyssomnias, Asthma, allergic inflammation, Speech Disorders | Altered Intercellular Communication | Children with asthma, hay fever, and food allergy may have several factors that increase their risk of speech disorder, including allergic inflammation, ADD/ADHD, and sleep disturbance. | 27091599 |
| Muscle tenderness, Inflammation, Certified Midwife | Altered Intercellular Communication | Expression of proinflammatory genes (eg, CCL8, TLR2) in the calvarial periosteum significantly increased in CM patients attesting to muscle tenderness, whereas expression of genes that suppress inflammation and immune cell differentiation (eg, IL10RA, CSF1R) decreased. | 27091721 |
| Inflammation, Sarcopenia | Altered Intercellular Communication | Sarcopenia, sarcopenic obesity and inflammation: Results from the 1999-2004 National Health and Nutrition Examination Survey. | 27091774 |
| PROS1 gene, Inflammation, Arthritis, Psoriatic | Altered Intercellular Communication | To investigate the association between clinical and ultrasonographic (US) evidence of inflammation in psoriatic arthritis (PsA), as well as to compare clinical and US remission criteria. | 27091837 |
| Inflammation | Altered Intercellular Communication | IL-15 is known to play an important role in neutrophil migration during inflammation. | 27093372 |
| Lymphoma | Altered Intercellular Communication | EBV-associated Peripheral T-Cell Lymphoma of Gastrointestinal Tract Presented With Widespread Chronic Inflammation: A Case Report. | 27093448 |
| Gastric Obstruction, Gastrointestinal tract structure, Gastrointestinal inflammation | Altered Intercellular Communication | We report a case of Epstein-Barr virus (EBV)-associated T-cell lymphoma of gastrointestinal (GI) tract from a 70-year-old white woman who initially presented with a widespread GI inflammation and gastric obstruction. | 27093448 |
| Inflammation | Altered Intercellular Communication | Initial biopsies of the GI tract showed severe chronic inflammation in the esophagus, stomach, and the small intestine. | 27093448 |
| T-Cell Lymphoma, Inflammation | Altered Intercellular Communication | Age-related immune senescence may have contributed to the uncontrolled GI inflammation and subsequent transformation to T-cell lymphoma. | 27093448 |
| Gingivitis, Inflammation | Altered Intercellular Communication | The gingival scores showed a mild inflammation and the prevalence of gingivitis was 91%. | 27093564 |
| Asthma, allergic inflammation | Altered Intercellular Communication | The mechanism of air pollution is not a classic allergic inflammation and could have differential effect on late-onset and early-onset asthma. | 27094099 |
| Psoriasis | Altered Intercellular Communication | Interleukins are involved in the development of psoriasis lesions through Th-17-associated inflammation. | 27094154 |
| Inflammation | Altered Intercellular Communication | Peripheral inflammation has been associated with adverse effects on cognition and brain structure in late life, a process called 'inflammaging.' | 27094339 |
| Inflammation | Altered Intercellular Communication | Peripheral inflammation related to lower fMRI activation during a working memory task and resting functional connectivity among older adults: a preliminary study. | 27094339 |
| Inflammation | Altered Intercellular Communication | Peripheral inflammation has been associated with adverse effects on cognition and brain structure in late life, a process called 'inflammaging.' | 27094339 |
| Inflammation, Impaired cognition | Altered Intercellular Communication | Identifying biomarkers of preclinical cognitive decline is critical in the development of preventative therapies, and peripheral inflammation may be able to serve as an indicator of cognitive decline. | 27094339 |
| Inflammation | Altered Intercellular Communication | However, little is known regarding the relationship between peripheral inflammation and brain structure and function among older adults. | 27094339 |
| Inflammation | Altered Intercellular Communication | Long-term subclinical inflammation may be the mechanism of this extraordinary aggressive clinical course. | 27094461 |
| Inflammation, Malnutrition, Hyponatremia | Altered Intercellular Communication | Unraveling the relationship between mortality, hyponatremia, inflammation and malnutrition in hemodialysis patients: results from the international MONDO initiative. | 27094625 |
| Inflammation, Malnutrition, Fluid imbalance, Hyponatremia | Altered Intercellular Communication | It is not well known to which extent the comorbidities, malnutrition, fluid status imbalance and inflammation are related to hyponatremia and affect outcomes. | 27094625 |
| Inflammation, Hyponatremia | Altered Intercellular Communication | Hyponatremia and inflammation were defined as serum sodium levels <135 mEq/l and C-reactive protein levels>6.0 mg/l, respectively. | 27094625 |
| Hypernatremia, Inflammation, Malnutrition, Hyponatremia | Altered Intercellular Communication | Hyponatremia was predicted by the presence of malnutrition (odds ratio (OR)=1.49 (95% confidence interval (CI)=1.30-1.70), inflammation (OR=1.44 (95% CI=1.26-1.64)) and fluid overload ((>+1.1 l to +2.5 l) OR=0.73 (95% CI=0.62-0.85)) but not by fluid depletion (OR=1.34 (95% CI=0.92-1.96)). | 27094625 |
| Hypernatremia, Inflammation, Malnutrition, Hyponatremia | Altered Intercellular Communication | Malnutrition, inflammation, fluid overload, fluid depletion and hyponatremia (hazard ratio=1.70 (95% CI=1.46-1.99)) were independent predictors for all-cause mortality. | 27094625 |
| Hypernatremia, Inflammation, Malnutrition, HD Term Type, Hyponatremia | Altered Intercellular Communication | In HD patients, hyponatremia is associated with malnutrition, inflammation and fluid overload. | 27094625 |
| Inflammation, Malnutrition, Hyponatremia, Congenital Abnormality | Altered Intercellular Communication | Hyponatremia maintained predictive for all-cause mortality after adjustment for malnutrition, inflammation and fluid status abnormalities. | 27094625 |
| Thyroid Diseases, Diabetes, Autoimmune, Diabetes Mellitus, Non-Insulin-Dependent | Altered Intercellular Communication | Common autoimmune biomarkers, thyroid hormonal abnormalities, and beta cells dysfunction in patients with latent autoimmune diabetes in adults with type II diabetes mellitus. | 27094870 |
| Inflammatory, Inflammatory abnormality of the eye, Behcet Syndrome | Altered Intercellular Communication | Behcet's disease is a progressive diffuse inflammatory vasculitis characterized by recurrent oral and genital ulceration and ocular inflammation. | 27095010 |
| Inflammatory abnormality of the eye, Diarrhea | Altered Intercellular Communication | She also had a history of recurrent diarrhea with a single episode of ocular inflammation in the recent past. | 27095010 |
| Inflammation, Injury of gastrointestinal tract, immunoglobulin A, Colitis | Altered Intercellular Communication | Adult mice colonized with LGG showed increased IgA production and decreased susceptibility to intestinal injury and inflammation induced in the dextran sodium sulfate model of colitis. | 27095077 |
| Inflammation, Injury of gastrointestinal tract, immunoglobulin A | Altered Intercellular Communication | Thus, neonatal colonization of mice with LGG enhances intestinal functional maturation and IgA production and confers lifelong health consequences on protection from intestinal injury and inflammation. | 27095077 |
| Respiratory Distress Syndrome, Adult, Inflammation, Lung Injury, Respiratory Distress Syndrome, Newborn, Pneumonia | Altered Intercellular Communication | Acute respiratory distress syndrome (ARDS) is a heterogeneous syndrome that occurs as a result of various risk factors, including either direct or indirect lung injury, and systemic inflammation triggered also by severe pneumonia (SP). | 27095254 |
| Diabetes Mellitus, Non-Insulin-Dependent, Inflammation, Complications of Diabetes Mellitus | Altered Intercellular Communication | Low-grade systemic inflammation is considered to participate in the progression of type 2 diabetes (T2D) and in diabetic complications. | 27095356 |
| Inflammation, Histologic type, Pain Distress Question | Altered Intercellular Communication | No significant correlations between the degree of inflammation, the histotype or invasiveness of SCCs, and the intensity of pain were found. | 27096539 |
| Inflammation, Dentition, Mixed, Granulomatous disorder, Vasculitis, CTCAE, Orbital Pseudotumor | Altered Intercellular Communication | Thirty-three (47.1%) had specific inflammation of the following subtypes: idiopathic sclerosing inflammation (n = 9), granulomatous disorders (n = 8), transitional lesions (n = 5), vasculitis (n = 4), and others (n = 7). | 27097061 |
| Granulation procedure, Neoplasms, Common wart, Granulomatous inflammation, Squamous cell carcinoma, Cutaneous Fibrous Histiocytoma | Altered Intercellular Communication | The changes of CPH overly traumatized neoplasms [ie, a poroma, squamous cell carcinoma (2), dermatofibroma], verruca vulgaris (3), inflammatory processes (lichen amyloid and granulomatous inflammation secondary to a ruptured infundibular cyst), and scar and fibrosing granulation tissue from previous procedures. | 27097239 |
| Hidradenitis Suppurativa, Abscess, Inflammation | Altered Intercellular Communication | Hidradenitis suppurativa (HS) is characterized by chronic inflammation, recurrent abscesses, and scarring. | 27097631 |
| Inflammation, Hypertension, CTCAE, Dyssomnias | Altered Intercellular Communication | Linking childhood abuse and hypertension: sleep disturbance and inflammation as mediators. | 27098168 |
| Inflammation, Hypertension, CTCAE, Dyssomnias | Altered Intercellular Communication | Childhood abuse was significantly related to both body mass index and sleep disturbance, which, both in turn, were significantly associated with inflammation, which was subsequently associated with hypertension status. | 27098168 |
| Inflammation, Hypertension, CTCAE, Dyssomnias | Altered Intercellular Communication | Sleep disturbance, body mass, and inflammation may be independent, intermediate steps between childhood abuse and subsequent hypertension that may be amenable to biobehavioral interventions. | 27098168 |
| Inflammation | Altered Intercellular Communication | Paleolithic and Mediterranean Diet Pattern Scores Are Inversely Associated with Biomarkers of Inflammation and Oxidative Balance in Adults. | 27099230 |
| Inflammation, Primary malignant neoplasm, Chronic disease | Altered Intercellular Communication | Chronic inflammation and oxidative balance are associated with poor diet quality and risk of cancer and other chronic diseases. | 27099230 |
| Discordance | Altered Intercellular Communication | A diet-inflammation/oxidative balance association may relate to evolutionary discordance. | 27099230 |
| Inflammation | Altered Intercellular Communication | These findings suggest that diets that are more Paleolithic- or Mediterranean-like may be associated with lower levels of systemic inflammation and oxidative stress in humans. | 27099230 |
| Chronic Kidney Diseases, Cardiovascular Diseases | Altered Intercellular Communication | Elevated serum fibroblast growth factor-23 (FGF23), an endogenous hormone, is associated with disturbed mineral homeostasis, cardiovascular disease, and chronic kidney disease. | 27100793 |
| glycation, Myeloid Leukemia, Chronic, Inflammation | Altered Intercellular Communication | Receptor for advanced glycation end products (RAGE) expressed on adipocytes and immune cells can bind to ligand N(e)-(carboxymethyl)-lysine (CML) and trigger dysregulation of adipokines and chronic inflammation. | 27100837 |
| Inflammation, Coronary Artery Disease, Atherosclerosis | Altered Intercellular Communication | Chronic inflammation promotes atherosclerosis and is a prognostic factor in coronary artery disease (CAD). | 27101443 |
| Inflammation, Metabolic Syndrome X | Altered Intercellular Communication | Increased oxidative stress and inflammation may play an important role in the high mortality of individuals with metabolic syndrome. | 27101758 |
| Inflammation, Diabetes Mellitus | Altered Intercellular Communication | Lifecourse socioeconomic status and type 2 diabetes: the role of chronic inflammation in the English Longitudinal Study of Ageing. | 27101929 |
| Inflammation, Ulceration, CTCAE, Dental Plaque, Cerebrovascular accident | Altered Intercellular Communication | Carotid intraplaque hemorrhage is associated with stroke, plaque thickness, stenosis, ulceration, and adventitial inflammation. | 27102316 |
| Inflammation, Eating | Altered Intercellular Communication | Change in serum lipids and markers of inflammation did not predict EAT progression. | 27102490 |
| Autoimmune Diseases, Vasculitis, AAVS1 gene | Altered Intercellular Communication | Anti-neutrophil cytoplasmic antibodies associated vasculitides (AAV) is a group of autoimmune diseases, characterized by small vessel inflammation. | 27102815 |
| Inflammation | Altered Intercellular Communication | During inflammation, P-selectin expressed on activated endothelial cells and platelets mediates rolling adhesion of leukocytes. | 27102967 |
| Inflammation, Damage | Altered Intercellular Communication | Soluble CD14 in cerebrospinal fluid is associated with markers of inflammation and axonal damage in untreated HIV-infected patients: a retrospective cross-sectional study. | 27103116 |
| Inflammation, Impaired cognition | Altered Intercellular Communication | Inflammation in the cerebrospinal fluid (CSF) has been associated with cognitive impairment, and CSF neurofilament light chain protein (NFL) and CSF neopterin concentrations are increased in those patients. | 27103116 |
| Inflammation, HIV Infections | Altered Intercellular Communication | Microbial translocation in HIV infection has been suggested to contribute to chronic inflammation, and lipopolysaccharide (LPS) and soluble CD14 (sCD14) are markers of microbial translocation and the resulting monocyte activation, respectively. | 27103116 |
| Inflammation, Damage, HIV Infections | Altered Intercellular Communication | We hypothesised that microbial translocation contributes to inflammation and axonal damage in the central nervous system (CNS) in untreated HIV infection. | 27103116 |
| Inflammation, Damage | Altered Intercellular Communication | CSF sCD14 were associated with markers of CNS inflammation and axonal damage. | 27103116 |
| Inflammation | Altered Intercellular Communication | This suggest that microbial translocation might be a driver of systemic and CNS inflammation. | 27103116 |
| Inflammation, Bothered by Vomiting, Diarrhea, Nausea, Dysgeusia, CTCAE, Fatigue | Altered Intercellular Communication | The most common treatment-related adverse events associated with gedatolisib were nausea (53%), mucosal inflammation (50%), decreased appetite (40%), diarrhea (38%), fatigue (35%), and dysgeusia and vomiting (each 30%). | 27103175 |
| Inflammation, Metabolic Syndrome X, Hyperglycemia, Hypertriglyceridemia, Hypertension, CTCAE | Altered Intercellular Communication | This association was robust to adjustments for other components of the metabolic syndrome (hypertriglyceridaemia, hypertension, hyperglycaemia and systemic inflammation). | 27103388 |
| Inflammation, Weight decreased, Obesity | Altered Intercellular Communication | Continued research into racial and sex differences in the relationship between obesity, inflammation, and health risks may ultimately lead to more personalized weight loss recommendations. | 27103770 |
| Granuloma, Swelling, Foreign-Body Reaction, Inflammation | Altered Intercellular Communication | In our opinion the painful swelling of the knee was due to a displacement of the pin that had been accidentally lodged in the soft tissues instead of the bone causing a foreign-body reaction resulting in granuloma formation with local inflammation. | 27104331 |
| ARCN1 gene, Inflammation, Chronic Obstructive Airway Disease | Altered Intercellular Communication | Vitamin D is suggested to play a role in airway and systemic inflammation in chronic obstructive pulmonary disease (COPD). | 27105006 |
| Inflammation | Altered Intercellular Communication | In addition, the increased expression of two major inflammatory cytokines in the EF in the L group may indicate that SEL is causally related to chronic inflammation. | 27105459 |
| Communicable Diseases, Gastrointestinal tract vascular insufficiency, Inflammation, Non-obstructive | Altered Intercellular Communication | The most frequent cause of PI was intestinal ischemia (n = 80,53.7 %), followed by infection (n = 18,12.1 %), obstructive (n = 12,8.1 %) and non-obstructive (n = 10,6.7 %) bowel dilatation, unknown aetiologies (n = 8,5.4 %), drugs (n = 8,5.4 %), inflammation (n = 7,4.7 %), and others (n = 6,4 %). | 27106233 |
| Malignant neoplasm of esophagus, Inflammation | Altered Intercellular Communication | Endoscopic ultrasonography suggested esophageal cancer, and chest computed tomography showed a mass in the lower esophagus surrounded by inflammation. | 27106429 |
| Inflammation, Metabolic Diseases, "Alzheimers Disease", Data types - Address | Altered Intercellular Communication | Epidemiological and genetic studies have identified metabolic disorders and inflammation as risk factors for Alzheimer's disease (AD). | 27106634 |
| Inflammation, Obesity, Diabetes Mellitus | Altered Intercellular Communication | Evidence in obesity and type-2 diabetes suggests a role for a metabolic inflammasome ("metaflammasome") in mediating chronic inflammation in peripheral organs implicating IKKb (inhibitor of nuclear factor kappa-B kinase subunit beta), IRS1 (insulin receptor substrate 1), JNK (c-jun N-terminal kinase), and PKR (double-stranded RNA protein kinase). | 27106634 |
| Inflammation | Altered Intercellular Communication | Inhibition of both TLR and IL signaling pathways may prevent joint inflammation and destruction. | 27108590 |
| Inflammation, Glaucoma, CTCAE | Altered Intercellular Communication | CONCLUSIONS In treating persistent inflammation in the course of glaucoma, antiglaucoma drugs may increase the permeability of the blood-ocular barrier, which may be connected with the lower concentration of serum ceruloplasmin in the glaucoma patients group. | 27109647 |
| ARCN1 gene, Inflammation, Lung diseases | Altered Intercellular Communication | The German COPD cohort study COSYCONET ("COPD and SYstemic consequences-COmorbidities NETwork") investigates the interaction of lung disease, comorbidities and systemic inflammation. | 27109808 |
| methyldopa, Inflammation | Altered Intercellular Communication | Chronic oxidative stress and subacute inflammation have been implicated as causes of age-related macular degeneration (AMD). | 27110092 |
| Inflammation, Malignant Neoplasms | Altered Intercellular Communication | Angiopoietins (Angs) play a pivotal role in angiogenesis and inflammation, and are associated with prognosis in malignancies. | 27111031 |
| Inflammation | Altered Intercellular Communication | Background Previous studies proposed that inflammation, oxidative stress, and impaired endothelial dysfunction have a crucial role in occurrence of saphenous vein graft (SVG) disease (SVGD). | 27111497 |
| Refractory anemias, Inflammation | Altered Intercellular Communication | Since SNS and HPA axis are activated in RA, inflammation might be accompanied by water retention. | 27112146 |
| Orbital Pseudotumor | Altered Intercellular Communication | Idiopathic orbital inflammation or orbital pseudotumor is rare in the pediatric population and may present with ocular findings not normally seen in the adult population. | 27112170 |
| Panuveitis, Orbital Pseudotumor | Altered Intercellular Communication | The authors report the case of a 14-year-old boy with idiopathic orbital inflammation who presented with bilateral panuveitis to highlight the features that make this diagnosis more difficult in the pediatric population. | 27112170 |
| Inflammation, Ischemic stroke | Altered Intercellular Communication | Low triiodothyronine: A new facet of inflammation in acute ischemic stroke. | 27112304 |
| Inflammation, Cerebrovascular accident | Altered Intercellular Communication | Inflammation is recognized as a key contributor to the pathophysiology of stroke. | 27112304 |
| Inflammation, Cerebrovascular accident | Altered Intercellular Communication | Low fT3 concentrations may be involved in the pathogenic pathway linking inflammation to stroke severity in AIS patients. | 27112304 |
| Inflammation, Asthma | Altered Intercellular Communication | We have shown that simultaneously increased local (Feno) and systemic (blood eosinophil) markers of type 2 inflammation related to a higher likelihood of BHR and uncontrolled asthma in a large cohort of young asthmatic patients. | 27113848 |
| Inflammation, vascular inflammations, SLC16A1 wt Allele | Altered Intercellular Communication | Serum hs-CRP, a systemic inflammation marker, and sVCAM-1, a vascular inflammation marker, reduced significantly in the flaxseed oil group at the end of week 8 compared to baseline (P < 0.05), and the reductions were significant in comparison with the MCT oil group (P < 0.05). | 27115157 |
| methyldopa, Age related macular degeneration, Chronic inflammation | Altered Intercellular Communication | Our previous study indicated that Ab-induced Retinal Pigment Epithelial (RPE) cell senescence may be associated with chronic inflammation in age-related macular degeneration (AMD). | 27115165 |
| methyldopa, Inflammation | Altered Intercellular Communication | In this AMD mouse model, Ab deposition and RPE senescence may be associated with AMD development, and RPE senescence is likely a mechanistic link between Ab deposition and inflammation. | 27115165 |
| Cessation of life, Chagas Disease, Cerebrovascular accident | Altered Intercellular Communication | Inflammation Enhances the Risks of Stroke and Death in Chronic Chagas Disease Patients. | 27115869 |
| Inflammation, Brain Injuries | Altered Intercellular Communication | Inflammation has been recognized as a key component in all ischemic processes, including the intravascular events triggered by vessel interruption, brain damage and repair. | 27115869 |
| Communicable Diseases, Inflammation | Altered Intercellular Communication | Given this, it is of particular importance to control intraoperative and postoperative intraocular pressure, infection, and inflammation which will contribute to decrease in the incidence of vitreoretinal complications after PK. | 27115992 |
| Inflammation | Altered Intercellular Communication | Its dysfunction associated with inflammation also binds to systemic complications. | 27116855 |
| Breast Carcinoma, Metabolic Syndrome X, Obesity | Altered Intercellular Communication | Obesity and metabolic syndrome are risk and prognostic factors for breast cancer (BC) and are associated with chronic inflammation. | 27117160 |
| Inflammation, Triple Negative Breast Neoplasms, Obesity | Altered Intercellular Communication | Before menopause, triple-negative cancers were related to obesity and chronic inflammation, and aggressive luminal subtypes to abdominal adiposity. | 27117160 |
| Inflammation, Cardiovascular Diseases | Altered Intercellular Communication | Systemic inflammation is an important risk factor for cardiovascular diseases and inequalities by race/ethnicity, gender, and education have been documented. | 27117593 |
| ARCN1 gene, Airway structure, Pulmonary Emphysema, Chronic Obstructive Airway Disease, Chronic lung disease | Altered Intercellular Communication | Chronic obstructive pulmonary disease (COPD) is a chronic lung disease characterized by chronic airway inflammation and emphysema, and is caused by exposure to noxious particles or gases, e.g. | 27117828 |
| Inflammation, Trichinellosis | Altered Intercellular Communication | Matrix metalloproteinase (MMP)-9: A realiable marker for inflammation in early human trichinellosis. | 27117947 |
| Inflammation | Altered Intercellular Communication | In conclusion, MMP-9 might be considered as a marker of inflammation in T. britovi patients. | 27117947 |
| Inflammation, Anti-Neutrophil Cytoplasmic Antibody-Associated Vasculitis, Autoimmune reaction, Necrosis | Altered Intercellular Communication | ANCA-associated vasculitis are severe autoimmune pathologies that are characterized by inflammation and necrosis of the small vessels. | 27118022 |
| Degenerative polyarthritis, Inflammation | Altered Intercellular Communication | In collagenase-induced OA knees, analyses of CatWalk, 2-deoxyglucose-probed fluorescence imaging, and mCT revealed that affected knees of TgHSP60 mice showed minor footprint irregularity, joint inflammation, and osteophyte formation. | 27118120 |
| Coronary Artery Disease, GDC AJCC Clinical Stage Terminology | Altered Intercellular Communication | MHR as a novel inflammation-based marker seemed to be an independent predictor of severity of coronary artery disease and future cardiovascular events in patients with ACS. | 27118231 |
| Inflammation | Altered Intercellular Communication | As a result of the relapsing B. cereus peritonitis diagnosis and a CT scan showing contraction of the peritoneum after longstanding inflammation, the peritoneal catheter was removed and the patient converted to haemodialysis. | 27118739 |
| Communicable Diseases, Inflammation | Altered Intercellular Communication | We aimed to explore the contribution of persisting inflammation to recovery, and investigated the potential role of human cytomegalovirus (HCMV) infection in its pathogenesis. | 27118812 |
| Renal Insufficiency, Inflammation, Chronic heart failure | Altered Intercellular Communication | Galectin-3 in patients with chronic heart failure: association with oxidative stress, inflammation, renal dysfunction and prognosis. | 27119370 |
| Abnormal renal function, Inflammation | Altered Intercellular Communication | Galectin-3 shows positive correlation with markers of oxidative stress, inflammation and kidney dysfunction. | 27119370 |
| Cessation of life, Inflammation | Altered Intercellular Communication | The patients had increased levels of most inflammatory biomarkers, albeit not all statistically significant, both at study entry and close to death, indicating ongoing inflammation. | 27119533 |
| Inflammation, Fibrosis Assessment, Heart failure | Altered Intercellular Communication | Galectin-3 (Gal-3) is involved in cardiac inflammation and fibrosis, and is in use as a biomarker that indicates increased risk in heart failure. | 27120522 |
| ARCN1 gene, Chronic Obstructive Airway Disease, Pneumonitis | Altered Intercellular Communication | Chronic obstructive pulmonary disease (COPD) is characterized by slowly progressive airflow limitaion, chronic lung inflammation and associated systemic manifestations. | 27121518 |
| ARCN1 gene, Tumor necrosis, Inflammation, Cardiovascular Diseases | Altered Intercellular Communication | The objective of this preliminary study was to investigate the levels of high sensitivity C reactive protein (hs CRP) and tumour necrosis factor-a (TNF-a) as markers of systemic inflammation and assessment of systemic vascular reactivity that may play an important role in development of cardiovascular disease in COPD patients. | 27121518 |
| Tumor necrosis, Inflammation | Altered Intercellular Communication | Tumour necrosis factor-a (TNF-a) and hs CRP were measured as markers of inflammation. | 27121518 |
| Inflammation, Impaired cognition | Altered Intercellular Communication | Pro-inflammatory markers like matrix metalloproteinases (MMPs) and their inhibitors (TIMPs) and S-100 Beta (S100B) may have a role in the early inflammation and cognitive decline following CEA. | 27121520 |
| Inflammation, Coronary Artery Disease | Altered Intercellular Communication | Inflammation in arterial walls leads to coronary artery disease (CAD). | 27121596 |
| Vasculitis, Coronary Arteriosclerosis, Coronary Artery Disease | Altered Intercellular Communication | Together, they suggest that low vascular SPMs may enable progression of chronic vascular inflammation predisposing to coronary atherosclerosis and to thrombosis.-Elajami, T. K., Colas, R. A., Dalli, J., Chiang, N., Serhan, C. N., Welty, F. K. Specialized proresolving lipid mediators in patients with coronary artery disease and their potential for clot remodeling. | 27121596 |
| Neurodegenerative Disorders, Inflammation, Presenile dementia, "Alzheimers Disease", Data types - Address | Altered Intercellular Communication | Notably, inflammation, MMPs, and AMPs are also involved in the etiopathogenesis of neurodegenerative disorders including certain forms of dementia such as Alzheimer disease (AD). | 27121663 |
| Refractory anemias, Arthritis | Altered Intercellular Communication | Early RA management should address psychosocial factors and comorbidities, as well as joint inflammation. | 27121777 |
| Pyogenic granuloma, Injury of nose | Altered Intercellular Communication | Our data further supports prior studies, suggesting that altered hormonal activity and nasal injury may increase the risk of developing nasal pyogenic granuloma. | 27122134 |
| methyldopa, Inflammation, Humor | Altered Intercellular Communication | Elevated levels of inflammation-related chemokines, including CXCL10, CCL14, CXCL16, CXCL7, and CCL22, in the aqueous humor of AMD patients may suggest a pathogenic role for inflammation. | 27122966 |
| Pituitary Neoplasms, OXSM gene, Acromegaly | Altered Intercellular Communication | As the simultaneous occurrence of KS and acromegaly is rare, and the association between them remains unclear, we suggest that complete pituitary hormonal screening and conventional pituitary MRI should be essential for patients with KS to screen for pituitary tumor. | 27124035 |
| Metastatic Gastric Adenocarcinoma | Altered Intercellular Communication | A Prognostic Model Using Inflammation- and Nutrition-Based Scores in Patients With Metastatic Gastric Adenocarcinoma Treated With Chemotherapy. | 27124056 |
| Sepsis, Inflammation, Bacterial Infections | Altered Intercellular Communication | Concentrations of TWEAK (but not GITRL) were further decreased in patients with sepsis and correlated with routinely used markers of inflammation and bacterial infection such as C-reactive protein, procalcitonin and Interleukin-6. | 27124414 |
| Retinal Detachment, Inflammation | Altered Intercellular Communication | On examination, anterior segment examination was quiet without any inflammation, anterior vitreous face showed 1+ cells, and dilated funduscopy revealed bilateral symmetrical serous retinal detachments along the posterior pole. | 27124790 |
| Inflammation, Fibrosis Assessment, Cutaneous Small Vessel Vasculitis | Altered Intercellular Communication | Histopathologic findings of small-vessel vasculitis, dermal fibrosis, and plasma cell infiltrates were uniformly present, and eosinophilic inflammation was frequent. | 27124923 |
| Inflammation | Altered Intercellular Communication | The evolving disease shows chronic inflammation of the synovium, which is a self-maintained process and an immunologically induced phenomenon. | 27125075 |
| Inflammation, Damage, Peripheral | Altered Intercellular Communication | The chronic inflammation of the synovium forms granulation tissue that invades peripheral joints towards the center and causes ligament cartilage and bone damage. | 27125075 |
| Rheumatoid Arthritis, Inflammation | Altered Intercellular Communication | In atlas and axis joints, rheumatoid arthritis causes the inflammation of bursa, synovium and joint capsule and leads to synovial pannus formation. | 27125075 |
| Hyponatremia | Altered Intercellular Communication | This study provides data supporting the view that mild hyponatremia during acute illnesses is related to a systemic inflammatory condition. | 27125438 |
| Arthritis | Altered Intercellular Communication | There was marked reduction in gut and peripheral joint inflammation, and less IFNg-producing and IL-17-producing CD8+ T cells, in Tbx21-/- compared with wild-type SKG mice. | 27125523 |
| APP gene, Aortic Aneurysm, Abdominal | Altered Intercellular Communication | Inflammation of the aortic wall is recognised as a key pathogenesis of abdominal aortic aneurysm (AAA). | 27126477 |
| Necrotizing granulomatous inflammation, B-Cell Lymphomas | Altered Intercellular Communication | Diffuse large B cell lymphoma with chronic granulomatous inflammation. | 27126666 |
| Granuloma, Neoplasms, Necrotizing granulomatous inflammation, Lymphoma, B-Cell Lymphomas | Altered Intercellular Communication | We report a case of diffuse large B cell lymphoma with chronic granulomatous inflammation to highlight awareness of obscure tumour cells within the granuloma, to avoid delay in diagnosis and management of lymphoma. | 27126666 |
| Necrotizing granulomatous inflammation, Tuberculosis | Altered Intercellular Communication | Chest X-ray showed an anterior mediastinal mass and computed tomography (CT)-guided biopsy was reported as chronic granulomatous inflammation suggestive of tuberculosis. | 27126666 |
| ARCN1 gene, Chronic Obstructive Airway Disease, Pneumonitis | Altered Intercellular Communication | Wingless/integrase-1 (WNT) signalling is associated with lung inflammation and repair, but its role in chronic obstructive pulmonary disease (COPD) pathogenesis is unclear. | 27126693 |
| vascular inflammations | Altered Intercellular Communication | Reduced miR-126 expression was accompanied by increased vascular inflammation as evident from the levels of vascular adhesion molecule-1 and fibrinogen, as well as leukocyte counts. | 27127202 |
| Airway structure, ARCN1 gene | Altered Intercellular Communication | Erythromycin was beneficial and reduced airway inflammation in COPD patients. | 27127346 |
| Airway structure | Altered Intercellular Communication | Underlying mechanisms may involve inhibition of IL-17 and IL-23 mediated airway inflammation. | 27127346 |
| Inflammation, Injury of kidney | Altered Intercellular Communication | So we hypothesized that the infiltration of neutrophils, inflammation factors, and aging markers , which were modulated by functional networks, induced the immune response and renal injury. | 27127888 |
| Inflammation | Altered Intercellular Communication | Inflammasome activation, with subsequent release of pro-inflammatory cytokines interleukin-1b (IL-1b) and IL-18, has recently been implicated in atherosclerosis-associated inflammation. | 27129183 |
| Inflammation | Altered Intercellular Communication | An immune phenotype characterized by increased immune activation, systemic inflammation, and accumulation of late-differentiated memory CD57(+) CD28(-) T cells has been associated with comorbidities in the elderly. | 27129782 |
| Inflammation | Altered Intercellular Communication | Periostin levels and eosinophilic inflammation in poorly-controlled asthma. | 27130294 |
| Inflammation, dupilumab | Altered Intercellular Communication | Dupilumab, a fully human anti-interleukin-4 receptor a monoclonal antibody, inhibits interleukin-4 and interleukin-13 signalling, key drivers of type-2-mediated inflammation. | 27130691 |
| Inflammation | Altered Intercellular Communication | Broccoli sprouts (BS) are the richest source of sulforaphane (SFN), which is a potent inducer of phase II enzymes, which play a critical role in preventing oxidative stress (OS) and inflammation. | 27130714 |
| Asthma, Pneumonitis, Atopy | Altered Intercellular Communication | Ingestion of whole BS for 3 days does not appear to improve eosinophilic pulmonary inflammation, inflammatory and OS biomarkers, or clinical features of asthma among atopic adults with asthma despite resulting in a marked increase in serum SFN levels. | 27130714 |
| Autoimmune Diseases, Inflammation, Thickening of left ventricular wall, Mitral Valve | Altered Intercellular Communication | Immunological and inflammatory processes in systemic autoimmune disease may not only cause pericardium inflammation, but may also cause mitral valve deterioration and left ventricular wall thickening. | 27131766 |
| Sandawe language, Inflammation | Altered Intercellular Communication | Immunological and inflammatory processes in SAD may not only cause pericardium inflammation, but may also cause MV deterioration and LV wall thickening. | 27131766 |
| Vascular Diseases, Dysplasia, Inflammation, Brain Neoplasms | Altered Intercellular Communication | Physiological (11)C-Met uptake, anatomical variations, vascular disorders, non-tumorous lesions such as inflammation or dysplasia, benign brain tumors and patient condition during (11)C-Met PET examination can potentially affect the image interpretation and cause false positives and negatives. | 27134530 |
| Acute and chronic inflammation | Altered Intercellular Communication | Chronic active mucosal inflammation accompanied 37.5% of the cases. | 27136106 |
| Inflammation, Ulceration, CTCAE, Distortion, Congestion | Altered Intercellular Communication | No statistically significant difference was found between parasite subspecies regarding presence of inflammation, lymphoid aggregates, architectural distortion, congestion, ulceration and increase of eosinophils. | 27136106 |
| Inflammation, Granuloma | Altered Intercellular Communication | Parasites induce nonspecific inflammation, slight mucosal architectural changes, mild eosinophilic infiltrate or granuloma formation. | 27136106 |
| Lichen - organism, Inflammation, Tinea Capitis | Altered Intercellular Communication | Endothrix tinea capitis owing to Trichophyton tonsurans commonly produces generalized scaling and localized perifollicular inflammation reminiscent of lichen planopilaris. | 27136624 |
| Inflammation, Transplant glomerulopathy, graft loss | Altered Intercellular Communication | Human leukocyte antigens (HLA) class II donor-specific antibodies (DSAs) are associated with microcirculation inflammation, transplant glomerulopathy and ultimately graft loss. | 27137749 |
| Inflammation, Radiculopathy, Polyneuropathy | Altered Intercellular Communication | On multivariate logistic regression analysis duration of symptoms since the onset (OR 1.007; 95 % CI 1-28, p = 0.01), polyneuropathy and radiculopathy (OR 5.4; 95 % CI 1.002-1.013, p = 0.044), cerebrospinal fluid (CSF)/serum glucose rate (OR 0.001; 95 % CI 000-0.067, p = 0.001), and CSF protein (OR 2.5; 95 % CI 2.3-2.7, p = 0.0001) were associated with diffuse inflammation. | 27138335 |
| Inflammatory abnormality of the eye, metabolic deficiency | Altered Intercellular Communication | Metabolic deficiency of o-3 tear film lipids may be a driver of chronic ocular surface inflammation in DE. | 27138739 |
| Inflammation, Thrombosis | Altered Intercellular Communication | Recently, platelet-to-lymphocyte ratio (PLR) has emerged as a new marker of worse outcomes linking inflammation and thrombosis. | 27138871 |
| Inflammation, Non-Small Cell Lung Carcinoma, Hypoxia, Neoplasms | Altered Intercellular Communication | Prognostic value of blood-biomarkers related to hypoxia, inflammation, immune response and tumour load in non-small cell lung cancer - A survival model with external validation. | 27139126 |
| Inflammation, Non-Small Cell Lung Carcinoma, Hypoxia, Neoplasms | Altered Intercellular Communication | Improve the prognostic prediction of clinical variables for non-small cell lung cancer (NSCLC), by selecting from blood-biomarkers, non-invasively describing hypoxia, inflammation and tumour load. | 27139126 |
| Diabetic Nephropathy, Inflammation, Cardiovascular Diseases | Altered Intercellular Communication | Common risk predictors included increasing age, cardiovascular disease history, primary diabetic nephropathy, low blood pressure, and inflammation. | 27140339 |
| Inflammation | Altered Intercellular Communication | Our study demonstrates that the targeted increase of gland permeability not only resulted in the restoration of secretory gland function but also resolved the hallmark salivary gland inflammation and systemic inflammation associated with disease. | 27140635 |
| Thrombosis | Altered Intercellular Communication | In contrast to patients without device thrombosis, all patients with device thrombosis had a pre-existing systemic inflammatory condition. | 27140700 |
| Thrombosis | Altered Intercellular Communication | Patients with pre-existing systemic inflammatory conditions are at risk of device thrombosis during DT. | 27140700 |
| Inflammation, Hypoglycemia, Obesity | Altered Intercellular Communication | Significant correlations were found between E-selectin and age, markers of glycaemia and inflammation, central obesity and lipid variables. | 27141013 |
| Inflammation, Corneal edema | Altered Intercellular Communication | Clinical improvement of coin-shaped lesions, other types of keratic precipitates, corneal oedema, and anterior chamber inflammation was confirmed at the 4-week visit in all seven eyes. | 27142389 |
| Inflammation, Friedreich Ataxia | Altered Intercellular Communication | Dorsal root ganglia in Friedreich ataxia: satellite cell proliferation and inflammation. | 27142428 |
| Multiple Organ Failure | Altered Intercellular Communication | Immunoglobulin G4-related disease (IgG4-RD) is a recently recognized inflammatory condition with single- or multi-organ involvement. | 27142509 |
| Inflammation, Shock, Cardiogenic | Altered Intercellular Communication | Extracellular peroxiredoxin 1 (Prdx1) has been implicated to play a pivotal role in regulating inflammation; however, its function in tissue hypoxia-induced inflammation, such as severe cardiogenic shock patients, has not yet been defined. | 27142532 |
| Inflammation, Rheumatoid Arthritis | Altered Intercellular Communication | Increased Kappa/Lambda Hybrid Antibody in Serum Is a Novel Biomarker Related to Disease Activity and Inflammation in Rheumatoid Arthritis. | 27143816 |
| Refractory anemias | Altered Intercellular Communication | The increased k/l hybrid antibodies were associated with inflammatory conditions in RA. | 27143816 |
| Inflammation, Lymphoma | Altered Intercellular Communication | In five of seven patients with multiple biopsies at different time-intervals, the lymphoma was misinterpreted as representing chronic inflammation on an earlier biopsy. | 27144366 |
| Inflammation, Hyperplasia | Altered Intercellular Communication | In sinonasal biopsies with predominantly small lymphocytic infiltrates with admixed chronic inflammation, focal hypercellularity, focal surface ulceration or microscopic bone invasion by small lymphoid cells should alert pathologists to the possibility of small-cell predominant ENKTCL. | 27144366 |
| Inflammation, Obesity | Altered Intercellular Communication | Bisphenol A Promotes Adiposity and Inflammation in a Nonmonotonic Dose-response Way in 5-week-old Male and Female C57BL/6J Mice Fed a Low-calorie Diet. | 27145005 |
| Inflammation | Altered Intercellular Communication | BPA exposure increased circulating inflammatory factors and the local inflammation in white adipose tissues in both genders fed a chow diet, but not under high-fat diet. | 27145005 |
| Inflammation, Obesity | Altered Intercellular Communication | Obesity and Age-Related Changes in Markers of Oxidative Stress and Inflammation Across Four Generations. | 27145150 |
| ARCN1 gene, Inflammation, Chronic Obstructive Airway Disease | Altered Intercellular Communication | Chronic obstructive pulmonary disease (COPD) is a condition characterized by systemic low-grade inflammation that could increase the production of nitric oxide (NO), of which arginine is the sole precursor. | 27146652 |
| Inflammation, Neoplasms | Altered Intercellular Communication | Inflammation is a critical component involved in tumor progression. | 27146881 |
| Massive Osteolyses, Inflammation, Prostate carcinoma, Gall Bladder Diseases | Altered Intercellular Communication | Chronic inflammation and abnormal cholesterol metabolism are involved in the pathogenesis of gallbladder stone disease (GSD) and that of prostate cancer in experimental studies. | 27147576 |
| Communicable Diseases, Fibrosis Assessment, Inflammation, Primary malignant neoplasm | Altered Intercellular Communication | Profiling analyses indicated that HCV infection differentially regulated the expression of 72 miRNAs by at least 2-fold, including miRNAs that were previously described to target genes associated with inflammation, fibrosis, and cancer development. | 27147737 |
| Colorectal Carcinoma | Altered Intercellular Communication | Relationship Between Chronic Inflammation and the Stage and Histopathological Size of Colorectal Carcinoma. | 27147782 |
| Inflammation, Primary malignant neoplasm, Neoplasms | Altered Intercellular Communication | The association of inflammatory reactions with almost all types of cancer supports the concept that inflammation is a critical component of tumor progression. | 27147782 |
| Inflammation, Colorectal Carcinoma | Altered Intercellular Communication | The present study aimed to evaluate the relationship of serum markers of chronic inflammation with the stage of and histopathological size of colorectal carcinoma (CRC). | 27147782 |
| Inflammation, Colorectal Carcinoma, Neoplasms | Altered Intercellular Communication | It was confirmed that increasing markers of inflammation followed increasing stages of colorectal cancer, depth of tumor invasion and the occurrence of metastatic disease. | 27147782 |
| Inflammation, Colorectal Carcinoma | Altered Intercellular Communication | The study results point to an increase in the degree of chronic inflammation throughout the progression of colorectal cancer. | 27147782 |
| Inflammation, Colorectal Carcinoma | Altered Intercellular Communication | The most consistent marker of chronic inflammation that accompanies the progression of colorectal carcinoma is CRP. | 27147782 |
| Pancreatic carcinoma | Altered Intercellular Communication | Clinical Implication of Inflammation-Based Prognostic Score in Pancreatic Cancer: Glasgow Prognostic Score Is the Most Reliable Parameter. | 27149487 |
| Pancreatic carcinoma | Altered Intercellular Communication | A variety of systemic inflammation-based prognostic scores have been explored; however, there has been no study to clarify which score could best reflect survival in resected pancreatic cancer patients.Between 2002 and 2014, 379 consecutive patients who underwent curative resection of pancreatic cancer were enrolled. | 27149487 |
| Duodenum, Neoplasms, Tumor Cell Invasion, Pancreatic carcinoma | Altered Intercellular Communication | There was also statistically significant correlation between the GPS score and tumor location (head), tumor size (>=2.0 cm), bile duct invasion, and duodenal invasion.Our study demonstrated that the GPS could be an independent predictive marker and was superior to other inflammation-based prognostic scores in patients with resected pancreatic cancer. | 27149487 |
| Inflammation | Altered Intercellular Communication | The patients with adult-onset inflammation of the middle ear, inner ear or both should undergo careful examinations, and they should be closely followed even if the diagnosis is uncertain. | 27149708 |
| Inflammation, Chronic Obstructive Airway Disease | Altered Intercellular Communication | We studied activation of hemostatic reactions together with mechanisms of systemic inflammation and genetic factors responsible for thrombogenic risk in 65 patients suffering exacerbation of chronic obstructive pulmonary disease with 2 or 3 positive criteria proposed by N.Anthonisen at al. | 27149808 |
| Inflammation, Tumor necrosis, Thrombin Time Test Device | Altered Intercellular Communication | The levels of indicators of systemic inflammation, such as C-reactive protein and tumour necrosis factor-alpha, increased concurrently with those of homocysteine, endothelin-1, Willebrand factor plasminogen activator inhibitor type 1, and thrombin-antithrombin complex (marker of thrombinemia). | 27149808 |
| Colorectal Carcinoma, peripheral blood, Colitis | Altered Intercellular Communication | CES-2 expression was analyzed by immunohistochemistry in colorectal cancer (CRC) compared to colonic inflammation as well as in liver and peripheral blood. | 27149931 |
| Primary malignant neoplasm, Gastrointestinal inflammation | Altered Intercellular Communication | Further studies should elucidate the role of CES-2(+) plasma cells in intestinal inflammation and cancer. | 27149931 |
| Inflammation, Necrosis, Eosinophilic Granuloma, Vasculitis, CTCAE, Systemic Vasculitis | Altered Intercellular Communication | A biopsy of the left peroneus brevis muscle showed active vasculitis with inflammation extending into muscle fascicles and fibrinoid necrosis of the vessel wall, consistent with eosinophilic granulomatosis with polyangiitis (EGPA). | 27150880 |
| Eosinophilic Granuloma, Systemic Vasculitis, Inappropriate ADH Syndrome | Altered Intercellular Communication | Syndrome of Inappropriate Antidiuretic Hormone Associated with Eosinophilic Granulomatosis with Polyangiitis. | 27150880 |
| Squamous cell carcinoma, Esophageal carcinoma | Altered Intercellular Communication | Inflammation-based prognostic system predicts postoperative survival of esophageal carcinoma patients with normal preoperative serum carcinoembryonic antigen and squamous cell carcinoma antigen levels. | 27151090 |
| Malignant Neoplasms | Altered Intercellular Communication | The Glasgow Prognostic Score (GPS) is an established inflammation-based system that is used to predict the prognosis for several types of malignancies. | 27151090 |
| Inflammation, multiorgan injury, Disease | Altered Intercellular Communication | Systemic inflammation has emerged as a key pathophysiological process that induces multiorgan injury and causes serious human diseases. | 27151398 |
| Inflammation, Inflammatory disorder | Altered Intercellular Communication | Endothelium is critical in maintaining cellular and inflammatory homeostasis, controlling systemic inflammation, and progression of inflammatory diseases. | 27151398 |
| Inflammation, physiopathological | Altered Intercellular Communication | To identify endothelial cell-released soluble factors that protect against endothelial barrier dysfunction and systemic inflammation. | 27151398 |
| Inflammatory | Altered Intercellular Communication | Candida-associated denture stomatitis is an infectious inflammatory condition of the oral mucosa, with frequent recurrences. | 27151707 |
| Inflammation, Fibrosis Assessment | Altered Intercellular Communication | CpG methylation at novel genes sheds light on new molecular pathways, which can be potentially exploited as a biomarker or targeted to attenuate inflammation and fibrosis. | 27152124 |
| Inflammation, Pancreatic carcinoma | Altered Intercellular Communication | A novel systemic inflammation response index (SIRI) for predicting the survival of patients with pancreatic cancer after chemotherapy. | 27152949 |
| Inflammation, Diabetic foot ulcer | Altered Intercellular Communication | Studies have emerged to demonstrate bidirectional changes in circulating cytokines of inflammation in active diabetic foot ulcers (DFU). | 27153203 |
| Inflammation, Colorectal Carcinoma, Neoplasms | Altered Intercellular Communication | Colorectal cancer (CRC) is one of the most common solid tumors worldwide, often associated with inflammation. | 27153562 |
| Colorectal Carcinoma | Altered Intercellular Communication | The microbes in the human intestine have a key role in inflammations and CRC. | 27153562 |
| chitotriose | Altered Intercellular Communication | Chitotriose renders growth advantage to some bacteria, especially some pathogens, and thus has a role in inflammations. | 27153562 |
| Epilepsy | Altered Intercellular Communication | Glutamate transporters manage glutamate levels and excitatory neurotransmission, and they have been associated with both epilepsy and TBI. | 27153812 |
| Inflammation, Skeletal muscle structure, Demographics Domain, Dermatomyositis, Disease | Altered Intercellular Communication | Dermatomyositis (DM) is a polygenic disorder characterized by inflammation of skeletal muscle and skin. | 27153935 |
| Airway structure, Asthma | Altered Intercellular Communication | Expression of miR-223-3p, miR-142-3p, and miR-629-3p is increased in sputum of patients with severe asthma and is linked to neutrophilic airway inflammation, suggesting that these miRNAs contribute to this asthma inflammatory phenotype. | 27155035 |
| Inflammation, Traumatic injury | Altered Intercellular Communication | Increased plasma nesfatin-1 concentrations are associated closely with inflammation, trauma severity and clinical outcomes, indicating that nesfatin-1 might be involved in inflammation and become a good prognostic biomarker following TBI. | 27155585 |
| Airway structure, SFC (Brand Name) | Altered Intercellular Communication | The use of SFC step-down resulted in somewhat better respiratory function, with no worsening of airway inflammation. | 27155753 |
| Inflammation | Altered Intercellular Communication | Adventitial inflammation was increased in CA IX-positive samples as compared with CA IX-negative ones (p < 0.01). | 27157093 |
| APP gene, Inflammation | Altered Intercellular Communication | This study demonstrates differential expression of transcripts in peripheral blood of individuals with AAA, with functional roles in proteolysis, inflammation, and apoptotic processes. | 27157464 |
| Intraocular inflammation, Uveitis | Altered Intercellular Communication | Uveitis is an intraocular inflammation affecting the highly vascularized uveal tissue. | 27159029 |
| Idiopathic Pulmonary Fibrosis | Altered Intercellular Communication | Immune Inflammation and Disease Progression in Idiopathic Pulmonary Fibrosis. | 27159038 |
| Inflammation, Idiopathic Pulmonary Fibrosis | Altered Intercellular Communication | In conclusion an innate and adaptive inflammation appears to be a prominent feature in the lung of patients with IPF and could contribute to determining of the rate of disease progression. | 27159038 |
| Inflammation, Primary malignant neoplasm | Altered Intercellular Communication | Activating transcription factor 3 (Atf3) has been implicated in the pathogenesis of various diseases, including cancer and inflammation, as well as in the regulation of cell proliferation and differentiation. | 27159257 |
| Inflammation, Foreign-Body Reaction | Altered Intercellular Communication | Histologic examination of the failed graft revealed skin with surface ulceration, focal abscess formation, deep penetrating acute and chronic inflammation with numerous eosinophils, and granulomatous changes demonstrating a foreign body-type reaction to fungal hyphae (highlighted by periodic acid-Schiff staining, Figures 1A-E). | 27159513 |
| vascular inflammations, Fibrosis Assessment | Altered Intercellular Communication | The profibrotic mediator Galectin-3 (Gal-3) has been associated with aldosterone-mediated vascular inflammation, fibrosis, and stiffness. | 27159890 |
| Airway structure, Asthma | Altered Intercellular Communication | A key therapeutic approach to asthma, which is characterized by chronic airway inflammation, is inhaled corticosteroid (ICS). | 27160342 |
| Airway structure, Symptoms | Altered Intercellular Communication | BHR to AMP may better reflect the relationship between improved airway inflammation due to ICS treatment and asthma symptoms. | 27160342 |
| Hyperplastic Polyp, Waldenstrom Macroglobulinemia | Altered Intercellular Communication | Compared with the hyperplastic polyps that lack the organisms, H pylori associated hyperplastic polyps more commonly had dense lymphoplasmacytic inflammation (P = .0001) and neutrophils within gastric epithelium (P = .036). | 27160432 |
| Acute Lung Injury, Inflammation | Altered Intercellular Communication | Acute lung injury (ALI) is characterized by rapid induction of inflammation at the alveolar-capillary membrane, and immunosuppressive mechanisms were shown to contribute to its resolution. | 27161112 |
| Inflammation, Ectogenesis, Epilepsy | Altered Intercellular Communication | Inflammation may be involved in the ictogenesis and development of some partial epilepsies. | 27161531 |
| Inflammation | Altered Intercellular Communication | Neutrophil-mediated inflammation may be important in the aetiopathogenesis of CSE. | 27161531 |
| Tremor | Altered Intercellular Communication | Mechanisms underlying VPA-induced tremors may involve abnormalities of DA and NE neurotransmitters. | 27161592 |
| Chronic Obstructive Airway Disease | Altered Intercellular Communication | Sarcopenic Obesity, Functional Outcomes, and Systemic Inflammation in Patients With Chronic Obstructive Pulmonary Disease. | 27161848 |
| Inflammation, Cardiac Hypertrophy | Altered Intercellular Communication | Recent studies have suggested that serum uric acid (SUA) induces oxidative stress and inflammation, which are involved in the mechanism of cardiac hypertrophy. | 27162100 |
| Inflammation, Arterial aneurysm, Intestinal necrosis | Altered Intercellular Communication | Mesenteric lesions involved intense arterial remodeling, progressive inflammation, occluded lumens, and less frequently intestinal necrosis and multiple visceral arterial aneurysms. | 27162120 |
| Atheroma, Atherosclerosis | Altered Intercellular Communication | Imaging Intraplaque Inflammation in Carotid Atherosclerosis With 18F-Fluorocholine Positron Emission Tomography-Computed Tomography: Prospective Study on Vulnerable Atheroma With Immunohistochemical Validation. | 27162131 |
| Atheroma | Altered Intercellular Communication | We hypothesized that (18)F-FCH could similarly be a valuable imaging tool to identify vulnerable plaques and associated intraplaque inflammation and atheroma cell proliferation. | 27162131 |
| Chronic tubulointerstitial nephritis, Inflammation, Fibrosis Assessment | Altered Intercellular Communication | Inflammation in Early Kidney Allograft Surveillance Biopsies With and Without Associated Tubulointerstitial Chronic Damage as a Predictor of Fibrosis Progression and Development of De Novo Donor Specific Antibodies. | 27163535 |
| Inflammation, Fibrosis Assessment, Tubular atrophy, Interstitial inflammation | Altered Intercellular Communication | Interstitial fibrosis and tubular atrophy (IFTA) associated with interstitial inflammation in nonscarred areas (IFTA+i) is associated with poorer graft outcome than inflammation without IFTA or IFTA without inflammation. | 27163535 |
| Inflammation | Altered Intercellular Communication | The histological diagnosis at 6 weeks was: normal (n = 206), inflammation (n = 29), IFTA (n = 255), and IFTA+i (n = 108). | 27163535 |
| Inflammation, Fibrosis Assessment | Altered Intercellular Communication | Moderate/severe interstitial fibrosis (ci>=2) at 1 year was observed in 4.2% of patients with prior (6 weeks) normal histology, in 3.4% with inflammation, in 13.8% with IFTA, and in 24.5% with IFTA+i (P = 0.0001). | 27163535 |
| Chronic tubulointerstitial nephritis, Inflammation | Altered Intercellular Communication | Early subclinical inflammation in surveillance biopsies with or without tubulointerstitial chronic lesions is associated with an increased risk of dnDSA development. | 27163535 |
| Inflammation, Diabetes Mellitus | Altered Intercellular Communication | Amylin from humans (but not rodents) has an increased propensity to aggregate into pancreatic islet amyloid deposits that contribute to b-cell mass depletion and development of type-2 diabetes by inducing oxidative stress and inflammation. | 27163815 |
| Celiac Disease, Inflammation, Hypertransaminasaemia, immunoglobulin A | Altered Intercellular Communication | According to ESPGHAN guidelines the finding of hypertransaminasemia as sign of celiac hepatic inflammation, a more than 10-fold increase of tTG IgA and a high-risk HLA would permit diagnosis of celiac disease but histological examination done due to mismatch between paucity of clinical sings and a "multiple risk combination" excluded it, allowing diagnosis of potential celiac disease. | 27163902 |
| Gastrointestinal inflammation | Altered Intercellular Communication | Upon recovery, fecal calprotectin, a marker of intestinal inflammation, was lower. | 27163928 |
| Inflammation, Primary malignant neoplasm | Altered Intercellular Communication | As observed in cancer immunotherapy, MDSCs could be a novel component in multimodality immunotherapy targeting detrimental inflammation and immunosuppression after SS/SS to improve currently observed dismal long-term outcomes. | 27163951 |
| Retinal Vasculitis, Vitreous inflammatory cells | Altered Intercellular Communication | Vision improved to 20/20 1 month postoperatively with complete resolution of vitreous inflammation and retinal vasculitis. | 27164507 |
| Pain Distress Question, vascular inflammations, Arthritis | Altered Intercellular Communication | Transient receptor potential canonical 5 (TRPC5) protects against pain and vascular inflammation in arthritis and joint inflammation. | 27165180 |
| Inflammation | Altered Intercellular Communication | A role for TRPC5 in inflammation has not been previously shown in vivo. | 27165180 |
| Inflammation, Hyperalgesia | Altered Intercellular Communication | Genetic deletion or pharmacological blockade of TRPC5 results in an enhancement in joint inflammation and hyperalgesia. | 27165180 |
| Rheumatoid Arthritis | Altered Intercellular Communication | Fibroblast-like synoviocytes (FLS) in rheumatoid arthritis (RA-FLS) contribute to joint inflammation and damage characteristic of the disease. | 27165430 |
| Psoriatic Juvenile Idiopathic Arthritis, Inflammation, Psoriasis | Altered Intercellular Communication | Lipocalin-2 might be a marker of psoriasis and convey cardiovascular or metabolic risk in psoriatic patients, but may not be a reliable indicator of inflammation, severity of psoriasis nor efficacy of antipsoriatic treatment. | 27165470 |
| Inflammation, Traumatic injury | Altered Intercellular Communication | He had no noteworthy medical or family history, and was not aware of any history of trauma or inflammation in his head or neck area. | 27165640 |
| Communicable Diseases, Inflammation | Altered Intercellular Communication | We administered antibiotics and non-steroidal anti-inflammatory drugs because we suspected that his symptoms were the result of inflammation caused by an infection. | 27165640 |
| Inflammation, chronic inflammatory response | Altered Intercellular Communication | HLA-DR/DQ testing revealed a multisusceptible haplotype for development of chronic inflammation, and serum chronic inflammatory response syndrome (CIRS) biomarker testing was positive for highly elevated TGF-beta and a clinically undetectable level of vasoactive intestinal peptide (VIP). | 27165859 |
| Inflammation, Coronary Artery Disease, Collagen Diseases | Altered Intercellular Communication | Rheumatologic disorders are characterised by inflammation and an increased risk of coronary artery disease (CAD). | 27166320 |
| Inflammation, Antiphospholipid Antibodies, Lupus Erythematosus, Systemic, Corneal Endothelial Cell Loss | Altered Intercellular Communication | Changes to fibrinolysis in patients with systemic lupus erythematosus are associated with endothelial cell damage and inflammation, but not antiphospholipid antibodies. | 27167859 |
| Inflammation, Lupus Erythematosus, Systemic, Antiphospholipid Antibodies, ATRICHIA WITH PAPULAR LESIONS, Lupus Erythematosus | Altered Intercellular Communication | We investigated whether changes to fibrinolysis were associated with other manifestations of systemic lupus erythematosus (SLE), including antiphospholipid (APL) antibody status, endothelial damage, and inflammation. | 27167859 |
| Inflammation, Lupus Erythematosus, Systemic, Corneal Endothelial Cell Loss | Altered Intercellular Communication | This study has demonstrated that fibrinolysis is significantly altered in patients with SLE compared to controls, and associated with endothelial cell damage and inflammation, but not APL antibody status. | 27167859 |
| Kidney Failure, Acute | Altered Intercellular Communication | Generally AKI is not induced by MCNS in youth, but it may occur under severe inflammatory conditions. | 27169260 |
| Inflammation, Ochronosis, Autosomal Recessive Disorder, Calcinosis, Alkaptonuria | Altered Intercellular Communication | Alkaptonuria, or ochronosis, a rare autosomal recessive metabolic disorder, causes an excess of homogentisic acid that results in dark pigmentation, calcification, and inflammation of cartilaginous and other tissues. | 27169295 |
| Inflammation | Altered Intercellular Communication | Inflammation may contribute to an increase in cardiac wall stress through pathways related to cardiac remodeling. | 27169396 |
| Inflammation, Myocytes, Cardiac | Altered Intercellular Communication | We sought to explore associations among cardiac remodeling, inflammation and myocardial cell injury in a bi-ethnic cohort of South African men and women. | 27169396 |
| Inflammation, Heart Ventricle | Altered Intercellular Communication | The susceptibility for cardiac wall remodeling appears to increase with hyperpulsatile pressure, low-grade systemic inflammation and ventricular stress, and may lead to the development of future cardiovascular events in African men. | 27169396 |
| Inflammation, Endothelial dysfunction, Atherosclerosis, Erectile dysfunction | Altered Intercellular Communication | Chronic inflammation may cause endothelial dysfunction and atherosclerosis, resulting in subsequent erectile dysfunction (ED). | 27169492 |
| Inflammation, Communicable Diseases, Local-Regional anatomy, Cacosmia Plant, Headache | Altered Intercellular Communication | The clinical signs of infection were: headache, locoregional pain, cacosmia, inflammation of the oral buccal mucosa and rhinorrhea or unilateral nasal discharge. | 27169511 |
| Inflammation, Coronary Artery Disease | Altered Intercellular Communication | Low vitamin B-6 status has been related to increased risk of coronary artery disease (CAD), which is a condition that is associated with inflammation. | 27169836 |
| Inflammation, Non-alcoholic Fatty Liver Disease, Prediabetes syndrome | Altered Intercellular Communication | Subclinical inflammation in relation to insulin resistance in prediabetic subjects with nonalcoholic fatty liver disease. | 27169860 |
| Metabolic Diseases, Non-alcoholic Fatty Liver Disease, Diabetes Mellitus, Non-Insulin-Dependent, Obesity | Altered Intercellular Communication | Nonalcoholic fatty liver disease (NAFLD) is a metabolic disease commonly associated with obesity, type 2 diabetes, and inflammation-all features of insulin resistant syndrome. | 27169860 |
| Inflammation, Non-alcoholic Fatty Liver Disease | Altered Intercellular Communication | However, very limited data are available regarding the association of subclinical inflammation and insulin resistance with NAFLD in a prediabetic state. | 27169860 |
| Inflammation, Non-alcoholic Fatty Liver Disease, Prediabetes syndrome | Altered Intercellular Communication | Subclinical chronic inflammation and insulin resistance seem to be independent mediators of the association between NAFLD and prediabetes. | 27169860 |
| Dyslipidemias, Prediabetes syndrome | Altered Intercellular Communication | The data also indicate that the inflammatory condition and insulin resistance are associated with each other and these, in turn, are affected by adiposity and dyslipidemia in prediabetic subjects. | 27169860 |
| Tumor necrosis, Inflammation | Altered Intercellular Communication | Tumor necrosis factor alpha (TNF-a), a multifunctional cytokine, is involved in apoptosis, cell proliferation, cell survival, and inflammation. | 27170003 |
| Inflammation | Altered Intercellular Communication | This process is mainly driven by chronic inflammation and an altered activity of a multitude of different chemokines and cytokines, resulting in the infiltration by immune cells (especially macrophages) and increase of matrix-expressing cell types. | 27170396 |
| Inflammation, Brain Damage, Chronic | Altered Intercellular Communication | The hepatic capacity to remodel scar tissue and to revert into a normal liver follows specific mechanistic principles that include the termination of chronic tissue damage, shifting the cellular bias from inflammation to resolution, initiation of myofibroblast apoptosis or senescence and, finally, fibrinolysis of excess scar tissue. | 27170396 |
| Inflammation | Altered Intercellular Communication | Another target is galectin-3 that acts at various stages along the continuum from acute to chronic inflammation. | 27170396 |
| methyldopa, vascular inflammations | Altered Intercellular Communication | Moreover, lipoprotein-associated phospholipase A2 activity, a marker of vascular inflammation, was decreased in AMD subjects (MD -24.1, p<0.01). | 27171197 |
| Bronchiectasis, Pulmonary Emphysema, Thickening of pleura, Calcinosis, Pneumonitis, Pneumonia, Interstitial | Altered Intercellular Communication | Preoperative chest CT was retrospectively reviewed to assess pleural thickening or calcification, pulmonary calcified nodules, active pulmonary inflammation, extent of emphysema, interstitial pneumonitis, and bronchiectasis in the operated thorax. | 27171235 |
| Calcinosis, Pneumonitis | Altered Intercellular Communication | Localized pleural thickening was found in 8 patients (6.5%), localized pleural calcification in 8 (6.5%), pulmonary calcified nodules in 28 (22.6%), and active pulmonary inflammation in 22 (17.7%). | 27171235 |
| allergic inflammation, Fever, CTCAE | Altered Intercellular Communication | Lower Tregs and increased SOCS3 in combined heterozygotes and minor allele homozygotes may be relevant for hay fever development, pointing towards dysbalanced immune regulation and insufficient control of allergic inflammation. | 27171815 |
| Inflammation, Thrombosis, Coronary Artery Disease | Altered Intercellular Communication | Involvement of soluble CD40 ligand (sCD40L) in thrombosis and inflammation on the context of coronary artery disease is currently being revised. | 27172386 |
| Inflammation, Primary malignant neoplasm, Cardiovascular event, Cessation of life, Cardiovascular system | Altered Intercellular Communication | Comparison of the Predictive Value of GlycA and Other Biomarkers of Inflammation for Total Death, Incident Cardiovascular Events, Noncardiovascular and Noncancer Inflammatory-Related Events, and Total Cancer Events. | 27173011 |
| Inflammation, Chronic Kidney Diseases, Cerebrovascular accident | Altered Intercellular Communication | There are hypotheses that novel non-traditional risk factors, like chronic inflammation and oxidative stress, are involved in chronic kidney disease, affecting the cerebral microvasculature that would in turn lead to stroke. | 27173119 |
| Inflammation, Herpes encephalitis | Altered Intercellular Communication | A study on viral CNS inflammation beyond herpes encephalitis. | 27173398 |
| Inflammation, Malignant neoplasm of gallbladder, Biliary calculi | Altered Intercellular Communication | Most gallbladder cancer (GBC) cases arise in the context of gallstones, which cause inflammation, but few gallstone patients develop GBC. | 27173614 |
| Biliary calculi | Altered Intercellular Communication | We explored inflammation/immune-related markers measured in bile and serum in GBC cases compared to gallstone patients to better understand how inflammatory patterns in these two conditions differ. | 27173614 |
| Inflammation, Biliary calculi | Altered Intercellular Communication | GBC is associated with inflammation above and beyond that generated by gallstones alone. | 27173614 |
| Intestinal metaplasia, Inflammation | Altered Intercellular Communication | Telomere shortening in non-neoplastic mucosa was associated with chronic inflammation (P = 0.0018) and intestinal metaplasia (P < 0.0001). | 27173780 |
| Pneumonitis | Altered Intercellular Communication | Secondary outcomes included patient activation, prescribing, adherence, spirometry, lung inflammation and health service contacts after 12 weeks. | 27173807 |
| Inflammation, Hormone refractory prostate cancer | Altered Intercellular Communication | As an acute-phase protein synthesized in response to systemic inflammation, the C-reactive protein (CRP) has been shown to be an independent prognostic factor for patients with castration-resistant prostate cancer (CRPC). | 27174032 |
| Inflammation | Altered Intercellular Communication | Our data suggest that both low and high birth weights are associated with greater visceral adiposity and biomarkers implicated in insulin resistance and inflammation in adolescents. | 27174144 |
| Inflammation, Primary malignant neoplasm | Altered Intercellular Communication | In addition to its classical endocrine character known for hemodynamic regulation, the renin-angiotensin system (RAS) can be associated with inflammation, wound healing, and cancer. | 27174460 |
| Inflammation, Cardiovascular Diseases | Altered Intercellular Communication | Influences on plasminogen activator inhibitor-2 polymorphism-associated recurrent cardiovascular disease risk in patients with high HDL cholesterol and inflammation. | 27174532 |
| Inflammation, Electrocardiogram: myocardial infarction (finding) | Altered Intercellular Communication | To investigate this issue, we have studied a group of post-myocardial infarction patients with high levels of C-reactive protein as an indicator of chronic inflammation and with concurrently high levels of HDL cholesterol. | 27174532 |
| Inflammation, emotional dependency | Altered Intercellular Communication | These included racial dependency, platelet clot initiation and propagation, oxidative stress, inflammation effects on HDL metabolism and coagulation, and induction and termination of fibrinolysis. | 27174532 |
| Airway structure, MS4A2 wt Allele | Altered Intercellular Communication | In the active asthma model, the percentage of mediation was 28.6% for pulmonary function, 18.1% for atopy and 5.7% for airway inflammation. | 27174886 |
| Fibrosis Assessment, Interstitial inflammation, Neoplasms | Altered Intercellular Communication | The reasons for frozen section errors and deferrals included larger tumour volume, tumour located close to the visceral pleura, interstitial inflammation or fibrosis, absence of prominent atypia and differential morphology in the deeper levels of the paraffin block. | 27174927 |
| Inflammation, Fever, CTCAE, Exacerbation of cGVHD | Altered Intercellular Communication | Fever at diagnosis and severity of inflammation at TAB appear to predict the development of disease flares. | 27175649 |
| APP gene, Aortic Aneurysm, Abdominal | Altered Intercellular Communication | Although the precise mechanisms underlying the pathogenesis of abdominal aortic aneurysm (AAA) remain unclear, aortic wall inflammation has been implicated in AAA development. | 27175690 |
| Rupture | Altered Intercellular Communication | The scans revealed chronological changes in aortic wall inflammation leading to progress and eventual rupture.This case supports a notion that aortic wall inflammation plays a role in AAA progression and rupture. | 27175690 |
| Gingivitis, VWF wt Allele, Gingival Hemorrhage, von Willebrand Disease, Type 3 | Altered Intercellular Communication | Gingival bleeding in VWD patients may be triggered by gingival inflammation, but it is not a genuine symptom of mild type 1 VWD. | 27177144 |
| Inflammation, Toxic effect | Altered Intercellular Communication | Aerosol IL-2 selectively increased infiltration, retention, and proliferation of infused NK cells in the lung, and there was no local inflammation or toxicity in the lungs or any other organ. | 27177675 |
| Varices of ovary, Endometriosis | Altered Intercellular Communication | Ovarian varices may evolve with oxidative stress in the function of the ovary, provoking an imbalance in its genetic, hormonal, and immunologic aspects and provoking the chronic inflammatory process particular to endometriosis. | 27177709 |
| Inflammation, FAM126A gene | Altered Intercellular Communication | Survivin deficiency results in mitosis defect-associated senescence in HCC cells, which triggers local inflammation and increased TNFa. | 27177758 |
| Cholecystitis | Altered Intercellular Communication | Surgical outcomes depend among other factors on the extent of gallbladder inflammation. | 27177953 |
| Inflammation, Sleep Disorders | Altered Intercellular Communication | Sleep disorders (SDs), particularly sleep deprivation, may alter the immune system and induce systemic inflammation. | 27178314 |
| RANGAP1 wt Allele, Inflammation, Cardiovascular Diseases | Altered Intercellular Communication | SD individuals with moderate-to-high gingival inflammation showed a significantly increased risk of cardiovascular disease (1.39 [1.04-1.84]) compared to SD individuals with low or no gingival inflammation. | 27178314 |
| Gingivitis | Altered Intercellular Communication | Individuals with self-report SDs are at increased risk of gingival inflammation. | 27178314 |
| Inflammation, Cardiovascular Diseases | Altered Intercellular Communication | The coexistence of SDs and gingival inflammation is associated with an increased risk of cardiovascular diseases. | 27178314 |
| Airway structure, Asthma | Altered Intercellular Communication | Periostin may be a useful biomarker of T-helper type 2 eosinophilic airway inflammation and has been linked to remodeling in asthma. | 27178891 |
| Inflammation, Asthma | Altered Intercellular Communication | Serum periostin may be a candidate for a novel biomarker for not only eosinophilic inflammation but as a marker for airway remodeling in asthma. | 27178891 |
| Inflammation | Altered Intercellular Communication | Re-transfusion of lipid particles and activated leucocytes with shed mediastinal blood (SMB) can aggravate cardiopulmonary bypass-associated inflammation and increase the embolic load. | 27178989 |
| Diabetes Mellitus, Non-Insulin-Dependent | Altered Intercellular Communication | Inflammation biomarkers and mortality prediction in patients with type 2 diabetes (ZODIAC-27). | 27179179 |
| Inflammation, Venous stasis, International Classification of Disease, Ninth Revision | Altered Intercellular Communication | The National Inpatient Sample was queried to identify all Caucasian and African-American patients with a primary International Classification of Diseases, Ninth Revision (ICD-9) diagnosis code for venous stasis with ulceration (454.0), inflammation (454.1), or complications (454.2) from 1998 to 2011. | 27179983 |
| Communicable Diseases, vascular inflammations | Altered Intercellular Communication | Although interferon (IFN)-g-induced protein 10 (IP-10)/CXCL10 is induced during vascular inflammation, data on CXCL10 in R. conorii infection is scarce. | 27180202 |
| Inflammation | Altered Intercellular Communication | Two had histological features of chronic non specific inflammation. | 27180374 |
| Inflammation, Primary malignant neoplasm | Altered Intercellular Communication | Epigenetics is now considered to be crucially involved in normal genetics and differentiation and in pathological conditions, such as cancer, aging, and inflammation. | 27180790 |
| Inflammation | Altered Intercellular Communication | Our results suggest that epigenetic changes participate in chronic inflammation and aging in the palatine tonsils. | 27180790 |
| Inflammation, Infection, Kidney Diseases | Altered Intercellular Communication | Although the results do not lead to a direct treatment, the epigenetic pathogenesis of chronic inflammation, such as immunoglobulin A nephropathy, by focal infections will be described in greater detail in future studies, which will lead to new treatments being developed. | 27180790 |
| Inflammation, Acne, Synovitis, Osteitis, Sapho, Hyperostosis, Pustulosis of Palms and Soles | Altered Intercellular Communication | In consideration of subcutaneous humps in the sterno-clavicular area and palmoplantar pustulosis, we diagnosed him as having synovitis, acne, pustulosis, hyperostosis, osteitis (SAPHO) syndrome and speculated that it induced peri-osteal chronic inflammation in the sterno-clavicular area, resulting in occlusion of the adjacent bilateral subclavian veins. | 27181039 |
| Inflammation, Inflammatory disorder | Altered Intercellular Communication | T cell immunoglobulin and mucin domain-containing molecule 3 (Tim-3) has been reported as an important regulatory inflammation molecule, and plays a pivotal role in several inflammation-related diseases. | 27182056 |
| Diabetes Mellitus, Non-Insulin-Dependent, Disease | Altered Intercellular Communication | Obesity-associated insulin resistance in type 2 diabetes is a disorder in the balance between pro-inflammatory and anti-inflammatory signals. | 27182056 |
| Inflammation, Hepatobiliary Disorder, Fibrosis Assessment | Altered Intercellular Communication | Significant predictors of liver disease (stage >=2 fibrosis or stage 1 fibrosis plus grade >=2 inflammation), including demographic, clinical, and laboratory variables, were evaluated by means of univariate and multivariate logistic regression analyses. | 27182648 |
| Inflammation, Fibrosis Assessment | Altered Intercellular Communication | Among the patients, 75.5% (77/102) had grade 0-1 inflammation and 77.5% (79/102) had stage 0-1 fibrosis. | 27182648 |
| Inflammation, Diabetes Mellitus, Non-Insulin-Dependent, Obesity | Altered Intercellular Communication | Lately, low-grade inflammation is recognized as accompanying obesity, a known risk factor for type 2 diabetes. | 27182718 |
| Inflammation, Autonomic nervous system disorders | Altered Intercellular Communication | Chronic low-grade inflammation, insulin resistance, and autonomic dysfunction are present at an early age in obese youths; early detection of inflammation may facilitate meaningful lifestyle changes in this high-risk group. | 27182718 |
| Vascular Diseases | Altered Intercellular Communication | Furthermore, the high frequency of the small-vessel stroke subtype in AS patients indicates that small-vessel inflammation may be involved in the pathogenesis of vascular diseases in AS patients. | 27182728 |
| TNF protein, human, Airway structure | Altered Intercellular Communication | Hyperoxia-exposed RV-infected mice showed further increases in IL-12 and increased expression of IFN-g, TNF-a, CCL2, CCL3, and CCL4, as well as increased airway inflammation and responsiveness. | 27183577 |
| Inflammation, Respiratory Hypersensitivity, Hyperoxia, Residual volume | Altered Intercellular Communication | Hyperoxic exposure increases the activation of CD103(+), Clec9a(+) DCs, leading to increased inflammation and airway hyperresponsiveness upon RV infection. | 27183577 |
| Communicable Diseases, Inflammation, Venous Engorgement | Altered Intercellular Communication | The underlying etiology may be inflammation, infection, and associated venous congestion within the spinal canal. | 27184560 |
| Inflammation, Liver Cirrhosis | Altered Intercellular Communication | However, further exploration of areas regarding therapeutic strategy might be possible to support metabolic activity, decrease inflammation, or enhance regeneration for liver cirrhosis. | 27185598 |
| Hemorrhage, Urethritis | Altered Intercellular Communication | Cystoscopy was done in all patients which revealed bulbar urethral inflammation and hemorrhage in all. | 27186701 |
| Inflammation, Destruction (action) | Altered Intercellular Communication | The mechanism underlying the CNS pathology causing sequelae in TBE appears related to the grade of inflammation in CNS, rather than to direct neuronal destruction. | 27187756 |
| Aggressive Periodontitis | Altered Intercellular Communication | Gingival Inflammation and Aggressive Periodontitis in a Child with a Specific Antibody Deficiency. | 27188128 |
| Inflammation, Periodontitis | Altered Intercellular Communication | Exuberant gingival inflammation accompanied by periodontitis is a rare finding in a very young child and may indicate a defect in the host response. | 27188128 |
| Inflammation, Periodontal Route of Administration | Altered Intercellular Communication | A 5-year-old girl presented with persistent gingival inflammation and periodontal destruction. | 27188128 |
| Inflammation, Periodontitis | Altered Intercellular Communication | CPD/Clinical Relevance: This article describes a rare case of gingival inflammation accompanied by periodontitis in a very young child secondary to an underlying host antibody deficiency and details the investigation, management and clinical outcomes. | 27188128 |
| Stomatitis, Inflammation, Exanthema | Altered Intercellular Communication | The most frequent grade 3 adverse events were rash (59%), mucosal inflammation (26%), and stomatitis (18%). | 27188206 |
| Pancreatitis | Altered Intercellular Communication | They may be seen in patients with pancreatic inflammation or pancreatitis. | 27188399 |
| Inflammation | Altered Intercellular Communication | Comparing the diagnosis and alterations in lichenoid and sclerotic patterns and in chronic inflammation, we found statistically significant differences. | 27188744 |
| Sepsis, Communicable Diseases | Altered Intercellular Communication | Sepsis was associated with a 22.1% (95% confidence interval 17.5% to 26.7%) absolute increase in late mortality relative to adults not in hospital, a 10.4% (5.4% to 15.4%) absolute increase relative to patients admitted with non-sepsis infection, and a 16.2% (10.2% to 22.2%) absolute increase relative to patients admitted with sterile inflammatory conditions (P<0.001 for each comparison). | 27189000 |
| Inflammation, Fibrosis Assessment, Traumatic injury | Altered Intercellular Communication | Association of Urinary Biomarkers of Inflammation, Injury, and Fibrosis with Renal Function Decline: The ACCORD Trial. | 27189318 |
| Injury of gastrointestinal tract, Gastrointestinal inflammation | Altered Intercellular Communication | These findings suggest that dietary anemonin attenuates LPS-induced intestinal injury by improving mucosa restoration, alleviating intestinal inflammation and influencing TGF-b1 canonical Smads and EGFR signaling pathways. | 27189428 |
| Inflammation, Necrosis | Altered Intercellular Communication | Nevertheless, heart Fe in FA contributes to cardiomyocyte necrosis, inflammation, and scarring as the disease progresses. | 27189813 |
| Inflammatory Bowel Diseases, Inflammation, Psychologic, Somatization | Altered Intercellular Communication | Levels of psychological comorbidity and somatization were significantly higher among patients with true IBS-type symptoms than patients with quiescent IBD or occult inflammation. | 27189912 |
| ARCN1 gene, Chronic Obstructive Airway Disease | Altered Intercellular Communication | Macrophage migration inhibitor factor (MIF) is a pluripotent cytokine associated with several different inflammatory conditions, but its role within lung inflammation and chronic obstructive pulmonary disease (COPD) is unclear. | 27190066 |
| ARCN1 gene, Chronic Obstructive Airway Disease | Altered Intercellular Communication | Macrophage migration inhibitor factor (MIF) is a pluripotent cytokine associated with several different inflammatory conditions, but its role within lung inflammation and chronic obstructive pulmonary disease (COPD) is unclear. | 27190066 |
| Inflammation, Diabetes Mellitus, Non-Insulin-Dependent | Altered Intercellular Communication | Central arterial stiffness is associated with systemic inflammation among Asians with type 2 diabetes. | 27190079 |
| Inflammation, Diabetes Mellitus, Non-Insulin-Dependent | Altered Intercellular Communication | To examine the relationship between inflammation and central arterial stiffness in a type 2 diabetes Asian cohort. | 27190079 |
| Arterial Stiffness, glycation, Inflammation, Diabetes Mellitus, Non-Insulin-Dependent | Altered Intercellular Communication | Elevated high-sensitivity C-reactive protein and decreased soluble receptor for advanced glycation end products are associated with augmentation index and pulse wave velocity, respectively, suggesting the potential role of systemic inflammation in the pathogenesis of central arterial stiffness in type 2 diabetes. | 27190079 |
| Hereditary Autoinflammatory Diseases, Inflammation, Exanthema, Autosomal recessive inheritance, Cervical lymphadenopathy, Intermittent, Hyperimmunoglobulinemia D, Job Syndrome, Gastrointestinal symptom, Arthritis | Altered Intercellular Communication | Hyperimmunoglobulinaemia D syndrome (HIDS) is an autosomal recessive, autoinflammatory disease that is characterised with intermittent febrile episodes, cervical lymphadenopathy, rashes, arthritis and gastrointestinal symptoms associated with synovial or serosal inflammation. | 27190114 |
| Inflammation | Altered Intercellular Communication | While immunosuppression is the major determinant of poor outcomes during ART, baseline inflammation is an additional important factor, identifying a subgroup of young children with similar mortality. | 27190179 |
| Inflammation, Chronic Kidney Diseases | Altered Intercellular Communication | Genotypic and phenotypic predictors of inflammation in patients with chronic kidney disease. | 27190335 |
| Inflammation, Chronic Kidney Diseases | Altered Intercellular Communication | Here, it is applied to identify risk factors for inflammation in CKD. | 27190335 |
| Inflammation, Hereditary | Altered Intercellular Communication | These results indicate a larger involvement of hereditary factors in inflammation than might have been expected and suggest that inclusion of genotype features in risk assessment studies is critical. | 27190335 |
| Inflammation, Restless Legs Syndrome, Chronic Kidney Diseases | Altered Intercellular Communication | The RLS model demonstrates that inflammation in CKD is determined by an extensive panel of factors and may prove to be a suitable tool that could enable a much-needed multifactorial approach as opposed to the commonly utilized single-factor analysis. | 27190335 |
| Inflammation, Dyslipidemias, Chronic Kidney Diseases, Diabetes Mellitus | Altered Intercellular Communication | Diabetes, dyslipidaemia, inflammation and mineral-bone disorders play a role in the appearance of PAD in CKD. | 27190385 |
| Panuveitis, Ocular sarcoidosis, Skin structure of eyelid, Uveitis, conjunctiva, Orbital Pseudotumor | Altered Intercellular Communication | Ocular sarcoidosis was present in 32 patients (36.4% of all) and included: eyelid skin lesions (2.3%); orbital inflammation (2.3%); conjunctival lesions (7.9%); anterior uveitis (2.3%); intermediate uveitis (1.1%); posterior uveitis (15.9%); panuveitis (5.7%), and neuro-ophthalmologic manifestations (9.1%). | 27191355 |
| Inflammation, Dental Plaque | Altered Intercellular Communication | Consequently, ALDH2 gene silencing led to an increased en face plaque area, more unstable plaque with heavier accumulation of lipids, more macrophages, less smooth muscle cells and collagen, which were associated with aggravated inflammation. | 27191745 |
| Inflammation, Dental Plaque | Altered Intercellular Communication | These findings suggested that ALDH2 can influence plaque development and vulnerability, and inflammation via MAPK, NF-kB and AP-1 signaling pathways. | 27191745 |
| Refractory anemias, Inflammation, Erosion lesion, Rheumatoid Arthritis | Altered Intercellular Communication | The main aim of this study was to investigate the relationship between ultrasound (US) findings indicative of joint inflammation and US features characterising bone erosions at joint level in patients with rheumatoid arthritis (RA) in clinical remission. | 27192221 |
| Inflammation, Erosion lesion | Altered Intercellular Communication | An experienced sonographer blind to the clinical data performed the US examinations to detect and score signs of joint inflammation and bone erosions from second to fifth metacarpophalangeal (MCP) joints of both hands. | 27192221 |
| Refractory anemias, Inflammation, Erosion lesion | Altered Intercellular Communication | This is the first study providing evidence supporting the association between US bone erosions and the persistence of subclinical inflammation in RA patients in clinical remission. | 27192221 |
| melanoma, Inflammation, Neoplasms, Eczema | Altered Intercellular Communication | Case report of a 48-year-old woman with no significant medical history who first presented with an eczematous dermatitis on her torso, extremities, and buttocks and who subsequently developed thousands of pinpoint, histologically atypical melanocytic tumors and invasive melanoma within the areas of inflammation. | 27192392 |
| Carcinogenesis | Altered Intercellular Communication | In recent years, the relevance of the two diseases has drawn attention in terms of the close epidemiological connection and chronic inflammation-associated carcinogenesis. | 27192776 |
| Inflammation, Hyponatremia, Lupus Erythematosus, Systemic | Altered Intercellular Communication | Our study firstly showed that hyponatremia could reflect a disease activity and severe inflammation of SLE. | 27193532 |
| Inflammation, Primary malignant neoplasm | Altered Intercellular Communication | Cancer as a promoter of inflammation may be more likely to account for our findings than low-grade inflammation promoting cancer development. | 27194008 |
| Degenerative polyarthritis, Inflammation | Altered Intercellular Communication | Recent efforts in osteoarthritis (OA) research have highlighted synovial inflammation and involvement of immune cells in disease onset and progression. | 27194025 |
| Inflammation, Nerve Degeneration | Altered Intercellular Communication | We do this by evaluating mRNA and protein (immunohistochemical) markers of regeneration, neurodegeneration, myogenesis, cell cycle regulation, and inflammation. | 27195289 |
| Infection, Chronic inflammation, Chronic otitis | Altered Intercellular Communication | Surgical site infections after chronic otitis media surgery seem to be associated with factors related to the inflammatory state of the middle ear at the time of surgery in early infections and with chronic inflammation in late infections. | 27196077 |
| Inflammation, Coronary heart disease | Altered Intercellular Communication | Chronic inflammation may promote development of coronary heart disease. | 27196450 |
| Cerebral Amyloid Angiopathy, Vasculitis, Inflammation | Altered Intercellular Communication | Imaging Findings of Cerebral Amyloid Angiopathy, Ab-Related Angiitis (ABRA), and Cerebral Amyloid Angiopathy-Related Inflammation: A Single-Institution 25-Year Experience. | 27196463 |
| Cerebral Amyloid Angiopathy, vascular inflammations | Altered Intercellular Communication | Vascular inflammation is present in a subset of patients with cerebral amyloid angiopathy (CAA) and has a major influence in determining the disease manifestations. | 27196463 |
| Vasculitis, vascular inflammations, Inflammation | Altered Intercellular Communication | Patients were grouped into CAA alone (no vascular inflammation), Ab-related angiitis or ABRA (angiodestructive inflammation), and CAA-related inflammation or CAA-RI (perivascular inflammation). | 27196463 |
| Inflammation, Hemorrhage | Altered Intercellular Communication | In conclusion, leptomeningeal enhancement and lobar hemorrhage at presentation may enable differentiation between CAA with and without inflammation. | 27196463 |
| Inflammation, Lymphoma | Altered Intercellular Communication | However, the SUVmax ratio of the spleen/bone marrow of the lymphoma patients was significantly different from that of the inflammation patients (t = 2.426, P = 0.021 < 0.05). | 27196500 |
| Inflammation, Fatty degeneration | Altered Intercellular Communication | In the nontumoral liver, significant steatosis (>=5% of hepatocytes) was generally present (in 10/11 patients), with mild lobular inflammation and absence of ballooning in most cases. | 27196679 |
| Malignant neoplasm of urinary bladder | Altered Intercellular Communication | We evaluated the association of SNPs in inflammation-related genes with non-muscle-invasive bladder cancer (NMIBC) risk-of-recurrence and risk-of-progression. | 27197286 |
| Excessive tearing, Blepharitis | Altered Intercellular Communication | Ocular discomfort occurred in 43 of 49 patients in the fluorouracil group versus 36 of 49 in the placebo group, epiphora occurred in 24 versus five, and eyelid skin inflammation occurred in seven versus none. | 27198842 |
| Inflammation, Cerebrovascular accident | Altered Intercellular Communication | Inflammation and platelets at the acute event do not forecast long-term survival of stroke sufferers. | 27199199 |
| Inflammation | Altered Intercellular Communication | Correlation of A2bAR and KLF4/KLF15 with Obesity-Dyslipidemia Induced Inflammation in Uygur Population. | 27199507 |
| Inflammation | Altered Intercellular Communication | In vitro modeling of COPD inflammation and limitation of p38 inhibitor - SB203580. | 27199554 |
| ARCN1 gene, Inflammation | Altered Intercellular Communication | Systemic inflammation and steroid resistance are the hallmarks of COPD. | 27199554 |
| ARCN1 gene, Inflammation | Altered Intercellular Communication | Inhibition of p38 phoshorylation had a limited effect in restoring impaired lymphocyte function and suppressing inflammation induced by COPD serum, implying important p38-independent inflammatory mechanisms in COPD. | 27199554 |
| Inflammation | Altered Intercellular Communication | While it presents as cutaneous inflammation with painful and erythematous nodules which demonstrate ulceration, imaging features of this pathology are seldom described. | 27200166 |
| Inflammation, Necrosis | Altered Intercellular Communication | MR imaging with its excellent soft tissue contrast can be helpful in confirming the diagnosis, demonstrating imaging features of fat necrosis with surrounding inflammation as demonstrated in our patient. | 27200166 |
| Inflammation | Altered Intercellular Communication | Endoscopic inflammatory features show a weak correlation with histopathology but should not replace histologic indices of inflammation. | 27200524 |
| Inflammation, Dermatitis | Altered Intercellular Communication | The results demonstrate that genetic variations in genes related to inflammation and skin homeostasis can influence responses to irritants and may explain inter-individual variation in the development of subsequent contact dermatitis. | 27206134 |
| Inflammation, Sleep Apnea, Obstructive | Altered Intercellular Communication | Systemic inflammation in patients with compromised upper airway anatomy and primary snoring or mild obstructive sleep apnea. | 27207142 |
| Inflammation, Airway Compromise, Sleep Apnea, Obstructive, Snoring | Altered Intercellular Communication | Systemic inflammation is strongly associated with average and lowest SpO2, RDI and AI (and with HI) in snorers with compromised upper airway anatomy and is present even in patients with primary snoring and mild obstructive sleep apnea. | 27207142 |
| nervous system disorder | Altered Intercellular Communication | Metabolic and inflammatory conditions may lead to neurological disorders. | 27207447 |
| vascular inflammations | Altered Intercellular Communication | In all subjects, it decreased vascular inflammation marker soluble intercellular adhesion molecule-1 (-10%, P < 0.01). | 27207552 |
| Exanthema, Leukocytosis, Fever, CTCAE, Arthralgia, Hyperferritinaemia, Juvenile-Onset Still Disease | Altered Intercellular Communication | Adult-onset Still's disease (AOSD) is a systemic inflammatory condition of unknown aetiology characterized by typical episodes of spiking fever, evanescent rash, arthralgia, leukocytosis and hyperferritinemia. | 27207567 |
| Inflammation, Cervical dysplasia | Altered Intercellular Communication | Decreased RARb expression induces abundant inflammation and cervical precancerous lesions. | 27207583 |
| Inflammation, Carcinogenesis | Altered Intercellular Communication | Importantly, our results suggest that the low expression of RARb, may induce the down regulation of p16(INK4a), chronic inflammation and decreased apoptosis and may be involved in vulnerability to HR-HPV and early stage cervical carcinogenesis. | 27207583 |
| Inflammation, Chronic sinusitis, Craniosynostosis, Acute and chronic inflammation | Altered Intercellular Communication | This work sampled four different anatomical regions within the human nasal passage across a large cohort of individuals (n = 79) comprising individuals suffering from chronic nasal inflammation clinically known as chronic rhinosinusitis (CRS) and individuals not suffering from inflammation (CRS-free). | 27207744 |
| Inflammation, Necrosis, Cardiovascular system | Altered Intercellular Communication | In patients with STEMI, a multimarker strategy that combines biomarkers across pathobiological axes of myocardial stress, myocyte necrosis, and inflammation provides incremental prognostic information for prediction of cardiovascular death or HF. | 27207959 |
| Inflammatory Bowel Diseases | Altered Intercellular Communication | Its pathogenesis remains largely unknown, although frequent concomitant IBD hints towards common factors underlying gut and bile duct inflammation. | 27207975 |
| Inflammation, Complications of Diabetes Mellitus, Cardiac Arrhythmia | Altered Intercellular Communication | A1C is associated with diabetes complications but does not reflect glycemic variability (GV), which may worsen outcomes by inducing inflammation, oxidative stress, and cardiac arrhythmias. | 27208320 |
| Inflammation, Venous Thromboembolism, Electrocardiogram: myocardial infarction (finding), Obesity, vinyltriethoxysilane | Altered Intercellular Communication | Background Low-grade inflammation in obesity may be a shared pathway for the risk of venous thromboembolism (VTE) and myocardial infarction (MI). | 27208592 |
| Inflammation, vinyltriethoxysilane, Obesity | Altered Intercellular Communication | Conclusions Our findings suggest that low-grade inflammation, assessed by measurement of CRP, is associated with the risks of MI and VTE, and may be a shared pathway for MI and VTE in obesity. | 27208592 |
| Airway structure, Signs and Symptoms, Respiratory, Chronic Obstructive Airway Disease | Altered Intercellular Communication | Short-term exposure to high ambient air pollution increases airway inflammation and respiratory symptoms in chronic obstructive pulmonary disease patients in Beijing, China. | 27209003 |
| Refractory anemias, Inflammation | Altered Intercellular Communication | Arterial wall inflammation, bone marrow and splenic activity (index of progenitor cell activity) was assessed with (18)F-fluorodeoxyglucose ((18)F-FDG) positron emission tomography/computed tomography (PET/CT) in RA patients in remission (disease activity score (DAS28) <2.6 for >6 months) and healthy controls. | 27209093 |
| Refractory anemias | Altered Intercellular Communication | Overall, arterial wall inflammation was comparable in RA patients (n = 23) in long-term remission and controls (n = 17). | 27209093 |
| Disease, Arteritis | Altered Intercellular Communication | In these subjects, RA disease duration was the most important contributor to the level of arterial wall inflammation. | 27209093 |
| Inflammation, Experimental Organism Basal Cell Carcinoma, Neoplasms | Altered Intercellular Communication | The data analysis showed that inflammation in patients with basal cell carcinoma (BCC) positively correlated with advanced age (p < 0.01), tumor diameter (p < 0.05), and the appearance of ulceration (p < 0.001). | 27209420 |
| Aggressive course, Inflammation | Altered Intercellular Communication | The comparison between premalignant and malignant conditions showed that inflammation probability increases as we move toward the more aggressive tumor phenotypes. | 27209420 |
| Endocrine System Diseases, Neoplasms | Altered Intercellular Communication | Most reports have focused on the various hormonal combinations in double tumors rather than on any potential increased risk for residual mass or endocrinopathy. | 27209585 |
| Congenital bilateral aplasia of vas deferens | Altered Intercellular Communication | Rapamycin may alleviate inflammation-induced initiation and progression of CAVD. | 27209607 |
| Squamous cell carcinoma of esophagus | Altered Intercellular Communication | A Novel Inflammation-Based Stage (I Stage) in Patients with Resectable Esophageal Squamous Cell Carcinoma. | 27212808 |
| Squamous cell carcinoma of esophagus | Altered Intercellular Communication | In the current study, we proposed a novel inflammation-based stage, named I stage, for patients with resectable esophageal squamous cell carcinoma (ESCC). | 27212808 |
| Squamous cell carcinoma of esophagus | Altered Intercellular Communication | The inflammation-based stage (I stage) is a novel and useful predictive factor for CSS in patients with resectable ESCC. | 27212808 |
| Inflammation, Superficial ulcer | Altered Intercellular Communication | Magnetic Resonance Imaging-Detected Features of Inflammation and Erosions in Symptom-Free Persons From the General Population. | 27213695 |
| Inflammation, Damage, Rheumatoid Arthritis | Altered Intercellular Communication | The use of magnetic resonance imaging (MRI)-detected inflammation and joint damage in the diagnosis of rheumatoid arthritis is recommended by a European League Against Rheumatism imaging task force. | 27213695 |
| Inflammation | Altered Intercellular Communication | For analyses at the joint level, MRI-detected inflammation was considered present if both readers scored the image as positive. | 27213695 |
| Inflammation, Superficial ulcer | Altered Intercellular Communication | MRI-detected inflammation and erosions are prevalent in symptom-free persons from the general population, especially at older ages and at preferential locations. | 27213695 |
| Inflammation, Uveitis, Intermediate | Altered Intercellular Communication | The new combination surgery for wet age-related macular degeneration and concurrent chronic peripheral uveitis provides rapid reduction of inflammation in the extreme periphery of the fundus and a 1.5 times faster (as compared to traditional methods) primary restoration of topographic anatomy of the retina in the macular region. | 27213803 |
| Inflammation | Altered Intercellular Communication | Evaluation of a novel point-of-care test for active matrix metalloproteinase-8: agreement between qualitative and quantitative measurements and relation to periodontal inflammation. | 27214099 |
| Inflammation, Dental Plaque | Altered Intercellular Communication | Beside clinical variables for plaque and inflammation, aMMP-8 concentrations were determined in oral rinsing specimens by the enzyme-linked immunosorbent assay (ELISA) and by POC. | 27214099 |
| Inflammation, Dental Plaque | Altered Intercellular Communication | Patients who had positive aMMP-8 test results (POC) showed higher scores for plaque and inflammation. | 27214099 |
| Respiratory physiology, Pomalidomide-Cyclophosphamide-Dexamethasone Regimen, Ciliary Dyskinesia, Primary, 1, With Or Without Situs Inversus, Pneumonitis | Altered Intercellular Communication | Primary Cilia Dyskinesia (PCD) is a rare, genetically heterogeneous disease that causes chronic pulmonary inflammation and progressive loss of lung function due to the dysfunction of cilia. | 27214451 |
| Inflammation, Psoriasis, Obesity, Chronic inflammatory disorder | Altered Intercellular Communication | Since obesity is associated with increased and/or delayed resolution of inflammation observed in various chronic inflammatory diseases such as psoriasis, we investigated the impact of FFAs on human monocyte-derived and mouse bone marrow-derived dendritic cell (DCs) functions relevant for the pathogenesis of chronic inflammation. | 27214608 |
| Obesity | Altered Intercellular Communication | Interestingly, obesity in mice worsened a TH1/TH17-driven psoriasis-like skin inflammation. | 27214608 |
| Degenerative polyarthritis, Dermatitis | Altered Intercellular Communication | Strong correlation of the amount of total FFA, PA, and OA in serum with the severity of skin inflammation points to a critical role of FFA in obesity-mediated exacerbation of skin inflammation. | 27214608 |
| Inflammation, Psoriasis | Altered Intercellular Communication | Our data suggest that increased levels of FFAs might be a predisposing factor promoting a TH1/TH17-mediated inflammation such as psoriasis in response to an inflammatory danger signal. | 27214608 |
| Inflammation | Altered Intercellular Communication | Association Between Genetic Variation in FOXO3 and Reductions in Inflammation and Disease Activity in Inflammatory Polyarthritis. | 27214848 |
| Refractory anemias, Rheumatoid Arthritis, Inflammation | Altered Intercellular Communication | Genetic variation in FOXO3 (tagged by rs12212067) has been associated with a milder course of rheumatoid arthritis (RA) and shown to limit monocyte-driven inflammation through a transforming growth factor b1-dependent pathway. | 27214848 |
| Refractory anemias, Inflammation | Altered Intercellular Communication | Similarly, rs12212067 (a single-nucleotide polymorphism that increases FOXO3 transcription) was associated with reduced inflammation, both biochemically and clinically, and with lower RA activity scores. | 27214848 |
| Refractory anemias, Inflammation, Arthritis | Altered Intercellular Communication | Consistent with its known role in restraining inflammatory responses, FOXO3 limits the severity of in vivo arthritis and, through genetic variation that increases its transcription, is associated with reduced inflammation and disease activity in RA patients, effects that result in less radiographic damage. | 27214848 |
| Anemia | Altered Intercellular Communication | The Hema-Plot illustrated the dynamic character of Ret-He and Delta-He, notably in inflammation-based types of anemia like ACD or ACD/ IDA. | 27215087 |
| Inflammation, Friedreich Ataxia | Altered Intercellular Communication | For the first time in a genetic condition, we have also shown a disease-related increase in the frequency of Purkinje cell fusion and heterokaryon formation in Friedreich's ataxia cases; with evidence that underlying levels of cerebellar inflammation influence heterokaryon formation. | 27215193 |
| Refractory anemias, Inflammation, Rheumatoid Arthritis | Altered Intercellular Communication | A possible association between mucosal immunization and inflammation, as well as the initiation and propagation of rheumatoid arthritis (RA), is attracting renewed interest. | 27215344 |
| Airway structure | Altered Intercellular Communication | However, the role of the alarmin protein high-mobility group box 1 (HMGB1) in upper airway inflammation is unclear. | 27216346 |
| Airway structure | Altered Intercellular Communication | To determine if HMGB1 is present in the nasal mucosa and, if so, to elucidate its role in upper airway inflammation. | 27216346 |
| Airway structure | Altered Intercellular Communication | TNF-a stimulates the production of HMGB1, which, in turn, upregulates the production and secretion of IL-6 and IL-8 by nasal epithelial cells via toll-like receptor 4, which indicated that HMGB1 plays an important role in the pathogenesis of upper airway inflammation. | 27216346 |
| Rickettsia conorii, vascular inflammations, Boutonneuse Fever | Altered Intercellular Communication | Mediterranean spotted fever caused by Rickettsia conorii is a potentially lethal disease characterized by vascular inflammation affecting multiple organs. | 27217049 |
| Inflammation, Cartilage damage, Pain Distress Question | Altered Intercellular Communication | It leads to cartilage damage associated with subchondral bone changes and synovial inflammation, causing pain and disability. | 27217345 |
| Inflammation | Altered Intercellular Communication | These proteins are involved in inflammation, immune as well as in the proteasome activation occurring in situations of endoplasmic reticulum stress. | 27217411 |
| Inflammation, Chronic sinusitis, Craniosynostosis | Altered Intercellular Communication | Abnormal olfaction is common with chronic rhinosinusitis (CRS) and associates with various measures of sinonasal inflammation. | 27218483 |
| Inflammation, Aortitis | Altered Intercellular Communication | The higher frequency of active aortitis in patients with dissection suggests that active inflammation may play a role. | 27219304 |
| Inflammation, Arthritis | Altered Intercellular Communication | There was a brief period of migratory arthritis, followed by persistent, severe inflammation in 1 knee. | 27219308 |
| Cyst, Inflammation | Altered Intercellular Communication | The most common benign diagnoses were cysts (33%) and inflammation (22%). | 27220040 |
| Gastrointestinal inflammation, Ulcerative Colitis | Altered Intercellular Communication | Fecal Human Neutrophil Peptide Levels Correlate with Intestinal Inflammation in Ulcerative Colitis. | 27220673 |
| Inflammatory Bowel Diseases, Gastrointestinal inflammation | Altered Intercellular Communication | Fecal markers have recently been found to provide convenient and noninvasive assessment of intestinal inflammation in inflammatory bowel disease (IBD). | 27220673 |
| Inflammation, Cardiac complication | Altered Intercellular Communication | Inflammation is a common feature in dialysis patients and is associated with cardiovascular complications and poor outcome. | 27220753 |
| Inflammation | Altered Intercellular Communication | Measuring the variability of inflammatory markers may help in understanding underlying factors triggering inflammation. | 27220753 |
| palladium, HD Term Type, Inflammation | Altered Intercellular Communication | Here we explored factors associated with the magnitude and variability of inflammation markers in HD and PD patients. | 27220753 |
| Inflammation, Comorbidity | Altered Intercellular Communication | Information on comorbidity, protein-energy wasting (PEW) and medications was gathered at baseline, and information on symptoms potentially related to inflammation was gathered weekly. | 27220753 |
| Inflammation | Altered Intercellular Communication | PEW predicted increased inflammation variability after correcting for age, sex, dialysis vintage, modality and comorbidity. | 27220753 |
| Parkinson Disease, Inflammation, palladium | Altered Intercellular Communication | There is evidence for a relevant role of inflammation in the pathogenesis of Parkinson's disease (PD). | 27220776 |
| palladium, Unknown (origin) (qualifier value), Inflammation | Altered Intercellular Communication | Concomitant inflammation seems to be associated with idiopathic and LRRK2-associated PD. | 27220776 |
| Inflammation, Periodontitis | Altered Intercellular Communication | The prevalence of TTMV-222 in the periodontitis group (n = 150) was significantly higher than that in the healthy group (n = 150) (p = 0.032), suggesting that the new virus may be associated with inflammation in chronic periodontitis patients. | 27221159 |
| Intravascular thrombosis, Acute pulmonary embolism, Inflammation, APEX1 protein, human | Altered Intercellular Communication | In some patients, the disease is preceded by acute pulmonary embolism (APE), and is characterised by intravascular thrombosis, vasoconstriction, inflammation and remodelling of pulmonary arteries. | 27221958 |
| Inflammation, Malignant Neoplasms | Altered Intercellular Communication | Exclusion criteria included malignancy, inflammation, and recent operation. | 27221958 |
| Inflammation, muscle mass | Altered Intercellular Communication | Our results suggested that major contributing factors to PEW were reduced muscle mass, unintentional low dietary energy intake, lower amount of exercise, insulin resistance, and chronic inflammation. | 27222412 |
| Hyperglycemia, Fatty degeneration | Altered Intercellular Communication | At multivariate analysis, PCSK9 was associated with steatosis grade (p = 0.012), older age and lower BMI, independently of sex, hyperglycemia, and fibrosis/inflammation. | 27222915 |
| Proctitis, Ulcerative Colitis | Altered Intercellular Communication | Evaluation of biomarkers for ulcerative colitis comparing two sampling methods: fecal markers reflect colorectal inflammation both macroscopically and on a cellular level. | 27223407 |
| Inflammation, Ulcerative Colitis | Altered Intercellular Communication | Simple, objective and inexpensive tools for the assessment of mucosal inflammation in ulcerative colitis (UC) are highly desirable. | 27223407 |
| Inflammation, Ulcerative Colitis | Altered Intercellular Communication | The levels of inflammation markers in feces and patch fluid distinctly reflected active inflammation in UC. | 27223407 |
| Proctitis, Inflammation | Altered Intercellular Communication | Fecal markers reflect colorectal inflammation both macroscopically and on a cellular level, and may be useful for the evaluation of subclinical inflammation. | 27223407 |
| ACSM3 gene, Inflammation, Subarachnoid Hemorrhage, Ruptured cerebral aneurysm | Altered Intercellular Communication | Toll-like receptor (TLR) signalling begins early in subarachnoid haemorrhage (SAH), and plays a key role in inflammation following cerebral aneurysm rupture. | 27223696 |
| Inflammation | Altered Intercellular Communication | The pathogenesis of PCME remains unclear, but most authors agree that inflammation plays a major role in its development. | 27224076 |
| Inflammation, Secondary immune deficiency disorder | Altered Intercellular Communication | Laboratory tests showed no signs of inflammation but showed persistent low protein- and IgG- levels, indicating a secondary immunodeficiency. | 27224999 |
| Inflammation, Lower Urinary Tract Symptoms | Altered Intercellular Communication | These findings suggested the presence of a correlation between chronic inflammation and lower urinary tract symptoms (LUTS). | 27225056 |
| Inflammation | Altered Intercellular Communication | There was also evidence of increased inflammation (C-reactive protein) in current smokers, suggesting a potential mechanism for these relationships. | 27225196 |
| Hyperammonemia, Inflammation, Dysbiosis | Altered Intercellular Communication | The mechanisms behind HE are unclear although hyperammonemia and systemic inflammation through gut dysbiosis have been proposed. | 27225869 |
| helium, Inflammation, Dysbiosis, Hyperammonemia | Altered Intercellular Communication | We found that HE patients had a significantly worse cognitive performance, systemic inflammation, dysbiosis and hyperammonemia compared to controls and cirrhotics without HE. | 27225869 |
| Inflammation, Metabolic Syndrome X, MS gene | Altered Intercellular Communication | The study was aimed to compare the release of incretins and some of early markers of inflammation at the fasting and postprandial period induced by functional oral glucose as well as lipid load in healthy controls and patients with metabolic syndrome (MS) to see if functional tests may be helpful in searching for the inflammatory status of patients. | 27226181 |
| Inflammation, Metabolic Syndrome X, Obesity | Altered Intercellular Communication | The fat containing meals stimulate the long-lasting release of incretins, mainly GIP, parallel to the increase of the markers of low grade inflammation associating obesity in metabolic syndrome. | 27226181 |
| Inflammation, Psoriasis, Drug-Induced Ototoxicity | Altered Intercellular Communication | In severe psoriasis, liver impacting comorbidities and/or specific psoriatic inflammation, the latter mostly in PP cases, more than drug-related liver toxicity, appears to predominantly account for LTA. | 27226222 |
| Communicable Diseases, Inflammation | Altered Intercellular Communication | After 4 weeks of treatment, the inflammation and infection resolved, and the patient returned to best-corrected preinjection visual acuity. | 27227391 |
| Inflammation, White Spot Lesion | Altered Intercellular Communication | However, the white lesions reappeared, and the inflammation in the anterior chambers worsened. | 27227394 |
| Inflammation, Pseudotumor | Altered Intercellular Communication | Flow cytometry analysis showed that the peri-implant pseudotumor tissue expressed two principal phenotypes, namely macrophage-dominated and T-lymphocyte-dominated response; the average portions being 54% (macrophages) and 25% (T-lymphocytes) in macrophage-dominated inflammation and 20% (macrophages) and 54% (T-lymphocytes) in T-lymphocyte-dominated response. | 27227536 |
| Inflammation | Altered Intercellular Communication | Modification of fat metabolism may alter inflammation and disease severity. | 27227540 |
| Pain Distress Question, Inflammation | Altered Intercellular Communication | Palmitoylethanolamide (PEA), a fatty acid amide that is produced in many cells in the body, is thought to potentiate the action of endocannabinoids and to reduce pain and inflammation. | 27227691 |
| Triglycerides, Inflammation, Hypertension, CTCAE, Obesity | Altered Intercellular Communication | Cardiometabolic abnormalities were defined as 3 or more cardiometabolic risk factors (hypertension, impaired glycemic control, systemic inflammation, low high-density lipoprotein cholesterol, high triglycerides, and central obesity). | 27227974 |
| Inflammation, Prostate Cancer Outcomes Study, Endocrine System Diseases, Polycystic Ovary Syndrome | Altered Intercellular Communication | Polycystic ovarian syndrome (PCOS), the most common endocrine disorder of reproductive-aged women, is associated with systemic low-grade inflammation. | 27228368 |
| Papillary thyroid carcinoma | Altered Intercellular Communication | Papillary thyroid cancer is a disease that has been associated with chronic inflammation. | 27229482 |
| Inflammation | Altered Intercellular Communication | Histopathologically, perineural inflammation was not an uncommon feature of LS and thus may serve as a clue in the differentiation of LS from its mimickers. | 27229659 |
| Inflammation | Altered Intercellular Communication | Choroidal thickness was greater in ERM eyes with than without VMT possibly due to direct anteroposterior traction on the retina and choroid, increased vascular endothelial growth factor associated with stress on retinal pigment epithelial cells and inflammation. | 27229756 |
| Fibrosis Assessment, Necrosis with inflammation | Altered Intercellular Communication | In HBeAg-positive patients, AUCs of serum HBcrAg for predicting severe necro-inflammation and advanced fibrosis were greater than 0.70; using serum HBcrAg<=4.81x10(4)kUmL(-1) and <=2.45x10(4)kUmL(-1) as cutoffs, the sensitivities, specificities, accuracies for predicting severe necro-inflammation and advanced fbrosis were 0.697, 0.716, 0.711 and 0.818, 0.778, 0.785, respectively. | 27230224 |
| Fibrosis Assessment, Necrosis with inflammation | Altered Intercellular Communication | These results indicated favorable performances of serum HBcrAg for predicting severe necro-inflammation and advanced fibrosis in HBeAg-positive patients and significant necro-inflammation and significant fibrosis in negative patients. | 27230224 |
| Hepatitis C, Hepatitis | Altered Intercellular Communication | Hepatitis C virus (HCV) is one of the major causes of liver inflammation. | 27230511 |
| Refractory anemias | Altered Intercellular Communication | Tenascin-C, which is expressed during inflammatory conditions including RA, was seen in the articular cartilage of the incudomalleolar joints and the head of the stapes. | 27230945 |
| Inflammation, Chronic Kidney Diseases | Altered Intercellular Communication | Inflammation could be a causal factor in the progression of chronic kidney disease. | 27234728 |
| Inflammation, Acute epididymo-orchitis | Altered Intercellular Communication | The aim of this study was to assess the effect of systemic inflammation associated with acute epididymo-orchitis on testis steroidogenesis. | 27234858 |
| Inflammation, Bacterial Infections | Altered Intercellular Communication | There is a strong influence of ongoing systemic inflammation caused by bacterial infection on steroidogenesis in testis in acute epididymo-orchitis patients. | 27234858 |
| Colorectal Carcinoma, Gastrointestinal inflammation | Altered Intercellular Communication | IL-17 and IL-22 are linked to the development of intestinal inflammation and colorectal cancer (CRC). | 27235120 |
| Inflammation | Altered Intercellular Communication | Our results conclude that the complement system is activated in CNS during HSE in the acute phase, and interestingly also in later stages supporting previous reports of prolonged inflammation. | 27235358 |
| Inflammation | Altered Intercellular Communication | Local and chronic inflammation may be the driver of low-grade systemic inflammation. | 27235406 |
| Autoimmune Chronic Hepatitis, Insemination, Artificial, Homologous | Altered Intercellular Communication | Autoimmune hepatitis (AIH) is a chronic inflammatory condition of the liver in which the immunological mechanisms involved in tissue destruction and/or repair are still unclear. | 27236154 |
| Inflammation, Primary malignant neoplasm | Altered Intercellular Communication | The fibers are similar in size and morphology to some amphibolic asbestos fibers, whose inhalation can cause chronic inflammation and cancer. | 27236568 |
| Inflammation, Viral keratitis | Altered Intercellular Communication | Among clinically defined viral keratitis cases, a negative viral swab was predominantly (93 %) observed in cases with subepithelial inflammation and was significantly associated with an increased duration of symptoms (p = 0.003). | 27236644 |
| Intestinal metaplasia, Inflammation | Altered Intercellular Communication | Five patients were found to have associated intestinal metaplasia, and all but two had chronic inflammation. | 27237135 |
| Inflammation, Atherosclerotic lesion | Altered Intercellular Communication | Inflammation is highlighted in the pathogenesis and destabilization of atherosclerotic lesions. | 27237221 |
| Inflammation, Atherosclerotic lesion | Altered Intercellular Communication | Noninvasive identification of inflammation of atherosclerotic lesions has been challenging. | 27237221 |
| Inflammation, atherosclerotic | Altered Intercellular Communication | Therefore, we investigated the relationship between levels of circulating inflammatory markers and the degree of inflammation of atherosclerotic plaques shown by 18F-FDG uptake. | 27237221 |
| Inflammation, MS gene | Altered Intercellular Communication | In multiple sclerosis (MS) lesions blood-brain-barrier (BBB) breakdown is a common phenomenon delineating the phase of focal inflammation in developing MS lesions. | 27237759 |
| Inflammation | Altered Intercellular Communication | Although their association seems to be fortuitous, both can induce an important inflammation state that could lead to AA amyloidosis and require a close monitoring of clinical signs and acute-phase reactants. | 27238193 |
| Autoimmune Diseases, Inflammation, Systemic Vasculitis | Altered Intercellular Communication | On the other hand, microscopic polyangiitis (MPA) is a systemic autoimmune disease characterized by the inflammation of small vessels (arterioles, capillaries, and venules) mainly affecting the lung and kidney. | 27238624 |
| Inflammation, Diffuse alveolar hemorrhage, Scleroderma , Myositis, CTCAE 5.0, Pneumonia, Interstitial | Altered Intercellular Communication | The patient developed interstitial pneumonia with alveolar hemorrhage accompanied by myositis, scleroderma, and elevated anti-U1-RNP antibody and MPO-ANCA levels with substantial systemic inflammation. | 27238624 |
| Inflammation, Lung Diseases, Interstitial, Complication Aspects, Myositis, CTCAE 5.0 | Altered Intercellular Communication | Strong immunosuppressive therapy (corticosteroid, intravenous immunoglobulin, and cyclosporine A) ameliorated the myositis, interstitial lung disease, and inflammation, with the decrease of MPO-ANCA levels, despite that severe lung complications are often associated with poor outcomes. | 27238624 |
| Acute suppurative inflammation | Altered Intercellular Communication | Fine-needle aspiration cytology smears showed acute suppurative inflammation with presence of fluffy basophilic colonies on Hematoxylin and Eosin staining and branched, Gram positive filamentous bacilli on Gram staining. | 27238823 |
| Arthralgia, Inflammation, Fever, CTCAE | Altered Intercellular Communication | Four patients displayed an association of fever and arthralgia, and all nine patients consistently showed laboratory markers of inflammation. | 27238847 |
| Inflammation, Fracture, Osteopenia, Diabetes Mellitus | Altered Intercellular Communication | The underlying mechanisms for increased osteopenia and fracture rates in patients with diabetes are not well understood, but may relate to chronic systemic inflammation. | 27238921 |
| Inflammation, Periodontal Diseases, Diabetes Mellitus | Altered Intercellular Communication | We assessed the effect of treating periodontal disease (POD), a cause of chronic inflammation, on inflammatory and bone turnover markers in patients with diabetes. | 27238921 |
| Anorexia Nervosa | Altered Intercellular Communication | Chronic undernourishment in the course of anorexia nervosa leads to various metabolic and hormonal changes, which translates to the impaired functioning of the majority of systems and internal organs. | 27240513 |
| ARCN1 gene, Inflammation | Altered Intercellular Communication | Despite our hypothesis suggesting that the prevalence of RLS/WED in COPD is related with systemic inflammation, we did not find a significant association between hs-CRP and COPD cases with RLS/WED. | 27240804 |
| Inflammation | Altered Intercellular Communication | Different measures of body fat composition may vary in their relations to parameters of chronic inflammation. | 27241125 |
| Inflammation | Altered Intercellular Communication | VAT, SAT, BMI, and WC show distinct associations with parameters of chronic inflammation. | 27241125 |
| Refractory anemias, Rheumatoid Arthritis, Autoimmune Diseases | Altered Intercellular Communication | Rheumatoid arthritis (RA) is a systemic autoimmune disease characterized by a chronic relapsing-remitting joint inflammation. | 27241313 |
| Inflammation, Structure of posterior cerebral artery | Altered Intercellular Communication | Dietary interventions aimed at decreasing inflammation may be considered to improve survival of men with PCa. | 27242333 |
| Inflammation, Lupus Nephritis | Altered Intercellular Communication | Urinary soluble CD163 level reflects glomerular inflammation in human lupus nephritis. | 27242373 |
| Inflammation, Tissue injury, Kidney Diseases | Altered Intercellular Communication | In addition to classically activated macrophages that have effector roles in tissue injury, alternatively activated M2 macrophages are involved in the resolution of inflammation in animal models of kidney disease. | 27242373 |
| Inflammation | Altered Intercellular Communication | These findings indicate that the u-sCD163 level can serve as a biomarker for macrophage-dependent glomerular inflammation in human LN. | 27242373 |
| Inflammation, Lower Urinary Tract Symptoms | Altered Intercellular Communication | These findings provide new insights into the TLR4-amplified EMT process and the association between TLR4 levels and storage LUTS, suggesting chronic inflammation as vital to the pathogenesis of BPH. | 27243216 |
| Inflammation | Altered Intercellular Communication | Triggering receptor expressed on myeloid cells 1 (TREM-1) is a potent amplifier of inflammation. | 27243593 |
| Communicable Diseases, Inflammation | Altered Intercellular Communication | Medical imaging techniques are required to make a differential diagnosis and biological markers for inflammation and infection should be evaluated. | 27243805 |
| Seizures, vascular inflammations | Altered Intercellular Communication | A young female subject with ineffective pharmacological regulation of chronic vasoconstrictive-induced epilectic-like seizures was effectively treated with a dietary regimen targeted to promote vasodilatation and attenuate vascular inflammation. | 27245208 |
| Inflammation | Altered Intercellular Communication | Chemokines induce leukocyte chemotaxis and contribute to chronic inflammation. | 27245471 |
| Airway structure | Altered Intercellular Communication | Recent animal studies indicated that metformin can reduce airway inflammation. | 27245632 |
| Fibrosis Assessment, Interstitial inflammation, Kidney Diseases | Altered Intercellular Communication | Distribution and components of interstitial inflammation and fibrosis in IgG4-related kidney disease: analysis of autopsy specimens. | 27246178 |
| Fibrosis Assessment, Interstitial inflammation | Altered Intercellular Communication | Using 5 autopsy specimens, the present study histologically characterized the distribution and components of interstitial inflammation and fibrosis in IgG4-RKD. | 27246178 |
| Inflammation, Fibrosis Assessment | Altered Intercellular Communication | In conclusion, perivascular inflammation or fibrosis of medium- and small-sized vessels is a newly identified pathologic feature of IgG4-RKD. | 27246178 |
| Inflammation, Stanford Cancer Institute | Altered Intercellular Communication | However, urothelial inflammation and apoptosis after SCI were not significantly improved after three repeated BoNT-A injections. | 27249005 |
| Trachoma , Inflammation | Altered Intercellular Communication | These data indicate that the innate immune system is active in the immunopathology of trachoma, even in the absence of clinical inflammation. | 27249027 |
| Inflammation, Fibrosis Assessment | Altered Intercellular Communication | CTGF might provide a direct link between inflammation and fibrosis and could be a suitable target for therapeutic treatment to halt the progression of trachomatous scarring. | 27249027 |
| Human papilloma virus infection, Uterine Cervicitis | Altered Intercellular Communication | CONCLUSIONS Older age (41-66 years), presence of HPV infection, postmenopause, cervical inflammation, and smoking are strong risk factors for cervical lesions among women in rural areas of Henan province, China. | 27249229 |
| Inflammation, Endothelial dysfunction | Altered Intercellular Communication | SIRT6 is an important member of sirtuin family that represses inflammation, aging and DNA damage, three of which are causing factors for endothelial dysfunction. | 27249230 |
| Inflammation, Primary malignant neoplasm, Neoplasm Metastasis | Altered Intercellular Communication | Chronic inflammation is known to facilitate cancer progression and metastasis. | 27249999 |
| Inflammation, Neoplasms | Altered Intercellular Communication | Less is known about the effect of acute inflammation within the tumor microenvironment, resulting from standard invasive procedures. | 27249999 |
| Inflammation, Neoplasm Metastasis, Breast Carcinoma, Neoplasms | Altered Intercellular Communication | Therefore, biopsy-induced inflammation could have an impact on residual tumor cell progression and/or metastasis in human breast cancer. | 27249999 |
| Chronic thromboembolic pulmonary hypertension | Altered Intercellular Communication | Chronic Thromboembolic Pulmonary Hypertension Associated with Chronic Inflammation. | 27250055 |
| Inflammation | Altered Intercellular Communication | This case suggests that a relationship exists between chronic inflammation and CTEPH, and furthermore, may contribute towards elucidating the pathophysiology of CTEPH. | 27250055 |
| Inflammation, Infiltration, Psoriasis, Inflammatory dermatosis, Peeling of skin | Altered Intercellular Communication | Psoriasis is a chronic inflammatory skin disease characterized by plaques with inflammation, infiltration, hyper-/parakeratosis and desquamation. | 27250651 |
| Calcification of coronary artery, Chronic Kidney Diseases | Altered Intercellular Communication | Systemic Inflammation Is Associated With Coronary Artery Calcification and All-Cause Mortality in Chronic Kidney Disease. | 27251163 |
| Inflammation, Calcification of coronary artery, Chronic Kidney Diseases, SLC25A20 gene | Altered Intercellular Communication | Presence of systemic inflammation in chronic kidney disease (CKD) is associated with advanced coronary artery calcification (CAC). | 27251163 |
| Inflammation, SLC25A20 gene | Altered Intercellular Communication | We evaluated the associations between CAC, estimated glomerular filtration rate (eGFR) and all-cause mortality, to determine whether the associations differ according to the presence of systemic inflammation. | 27251163 |
| Inflammation, Cardiotoxicity, Takotsubo Cardiomyopathy, Colorectal Carcinoma, Coronary Artery Vasospasm | Altered Intercellular Communication | Despite the high therapeutic efficacy of 5-FU in treatment of colorectal cancer, it is associated with undesired cardiac toxicities including coronary spasms, toxic inflammation and takotsubo cardiomyopathy. | 27251602 |
| Granulomatous inflammation | Altered Intercellular Communication | Several punch biopsies exhibited non-specific granulomatous inflammation without demonstrable fungi or mycobacteria in histochemical stains. | 27251900 |
| Inflammation | Altered Intercellular Communication | It usually occurs in the setting of chronic inflammation. | 27252231 |
| Depression, CTCAE, Erectile dysfunction | Altered Intercellular Communication | Similarly, change in erectile dysfunction over time was associated with mortality over 7 years in univariate (odds ratio: 1.69, 95% CI: 1.34-2.14) and multivariate analysis, including hormones, but not after adjusting for depression (odds ratio: 1.24, 95% CI: 0.95-1.62). | 27252309 |
| Inflammation, Malignant Neoplasms, Cyst | Altered Intercellular Communication | The final diagnoses were malignant or premalignant tumors in 10 patients (29.4%), stones in nine patients (26.5%), inflammation in 14 patients (41.2%), and cyst in one patient (2.9%). | 27254755 |
| Inflammation, Neoplasms | Altered Intercellular Communication | The diagnostic accuracies of stones, inflammation, and AOV tumors were 100.0%, 94.1%, and 91.1%, respectively. | 27254755 |
| Inflammation, Fever, CTCAE | Altered Intercellular Communication | Clinically, most patients presented with fever and local inflammation. | 27255172 |
| Inflammation, Structure of beta Cell of islet, Diabetes Mellitus, Non-Insulin-Dependent | Altered Intercellular Communication | Pancreatic b-cell dysfunction resulting from inflammation has been recognized to contribute to type 2 diabetes mellitus (T2DM). | 27255377 |
| Inflammation, Carcinogenesis, Neoplasms | Altered Intercellular Communication | Emerging evidences indicate that inflammation plays a crucial role in carcinogenesis and tumor progression. | 27255479 |
| Inflammation, Fibrosis Assessment | Altered Intercellular Communication | iMAP depicted fibrosis in the vessel (green areas) and nonfibrotic tissue change suggestive of inflammation outside the vessel (yellow/red areas). | 27255645 |
| Arthralgia, Inflammation, Fever, CTCAE | Altered Intercellular Communication | A 4.5-year-old Caucasian boy presented with fever of 4 days' duration followed by debilitating migratory arthralgia and inflammation. | 27255933 |
| Granulomatous inflammation, Necrosis | Altered Intercellular Communication | Histological samples of affected organs taken from seven patients showed granulomatous inflammation in six, with caseating necrosis in five. | 27256154 |
| Inflammation | Altered Intercellular Communication | The stroma exhibited extensive desmoplasia and chronic inflammation. | 27256178 |
| Communicable Diseases, Inflammation | Altered Intercellular Communication | An attempt was made to find a diagnostic test capable of identifying the infectious process underway, but clinical scales and biomarkers of inflammation helped us to achieve acceptable results. | 27256282 |
| Alzheimers Disease", Inflammation | Altered Intercellular Communication | Genetic risk factors for Alzheimer's disease imply that inflammation plays a causal role in development of the disease. | 27256292 |
| Inflammation, Sleep Apnea, Obstructive, Blood Vessel, Osage language | Altered Intercellular Communication | Oxidative stress and inflammation are assumed as the main pathological triggers for vascular damage in hypersomnolent obstructive sleep apnoea (OSA) patients, whereas their exact role in less symptomatic population is currently unknown. | 27256793 |
| Inflammation, Blood Vessel, Osage language | Altered Intercellular Communication | To determine whether oxidative stress (urinary 8-isoprostane concentration) and inflammation (plasma resistin levels) are associated with vascular damage in non-hypersomnolent (Epworth Sleep Score <11) OSA patients. | 27256793 |
| Myocarditis | Altered Intercellular Communication | Endocardial inflammation is more common in left atrial appendage irrespective of rhythm. | 27256970 |
| Inflammation, Ischemic stroke, Brain Infarction | Altered Intercellular Communication | Although plasma C-reactive protein (CRP) is elevated in response to inflammation caused by brain infarction, the association of CRP with clinical outcomes after acute ischemic stroke remains uncertain. | 27258004 |
| Airway structure, Asthma, Bronchoconstriction | Altered Intercellular Communication | In asthma, FENO50 increases with bronchodilation and decreases with bronchoconstriction, the latter potentially causing an underestimate of the degree of airway inflammation when asthma worsens. | 27258087 |
| methyldopa, Inflammation | Altered Intercellular Communication | Age-related macular degeneration (AMD) is a multifactorial disease, in which complement-mediated inflammation plays a pivotal role. | 27258093 |
| Polyuria, Polydipsia, Nephrogenic Diabetes Insipidus, Nephrogenic Diabetes Insipidus, Type I | Altered Intercellular Communication | Nephrogenic diabetes insipidus (NDI) is a condition resulting from the kidney's impaired response to circulating antidiuretic hormone (ADH), leading to polydipsia and polyuria. | 27258490 |
| Dermatitis | Altered Intercellular Communication | He was found to have significant skin inflammation, predominantly involving areas of tattoos. | 27258541 |
| Inflammation | Altered Intercellular Communication | Skin biopsy demonstrated granulomatous inflammation of the dermis with tattoo pigment evident in numerous histiocytes. | 27258541 |
| Inflammation, Uveitis | Altered Intercellular Communication | The authors report another rare case of tattoo-associated uveitis, in which inflammation is limited to tattooed skin and the uvea. | 27258541 |
| Inflammation, Coronary Artery Disease | Altered Intercellular Communication | Aerobic, resistance and combined training and detraining on body composition, muscle strength, lipid profile and inflammation in coronary artery disease patients. | 27258806 |
| Inflammation | Altered Intercellular Communication | lipid and apolipoprotein profile and inflammation status) parameters, while the return to baseline values during the detraining period was slower compared to the other exercise modalities. | 27258806 |
| Allergic sensitization | Altered Intercellular Communication | The results are of interest as they demonstrate that genetic variations in inflammation-related genes within the MHC can influence chemical-induced skin irritation and may explain the connection between inflamed skin and propensity to subsequent allergic contact sensitization. | 27258892 |
| Inflammation, Primary malignant neoplasm | Altered Intercellular Communication | Conditioned medium derived from rat amniotic epithelial cells confers protection against inflammation, cancer, and senescence. | 27259996 |
| IL13 gene, Rhinitis | Altered Intercellular Communication | Allergic rhinitis (AR) occurs when the symptoms of rhinitis arise as a result of allergen-induced nasal mucosal inflammation. | 27260602 |
| Pleural Tuberculosis | Altered Intercellular Communication | It can result from diverse inflammatory conditions, especially tuberculous pleurisy. | 27261452 |
| Inflammation, Diabetes Mellitus | Altered Intercellular Communication | Executive functioning and diabetes: The role of anxious arousal and inflammation. | 27261922 |
| Inflammation, Diabetes Mellitus, Non-Insulin-Dependent | Altered Intercellular Communication | Chronically high anxious arousal and inflammation increase one's risk of developing type 2 diabetes. | 27261922 |
| Inflammation, Diabetes Mellitus | Altered Intercellular Communication | We sought to evaluate anxious arousal and inflammation as underlying mechanisms linking inhibition with diabetes incidence. | 27261922 |
| Inflammation, Carcinogenesis, ovarian neoplasm | Altered Intercellular Communication | While inflammation has been shown to play an important etiologic role in ovarian carcinogenesis, little is known about the association between inflammatory properties of diet and ovarian cancer risk. | 27262447 |
| Inflammation, Panuveitis, Uveitis | Altered Intercellular Communication | Volunteers with histories of unilateral or bilateral anterior segment inflammation (anterior, intermediate, or panuveitis); included were 52 patients (84 eyes with uveitis). | 27262766 |
| Cerebrovascular accident | Altered Intercellular Communication | Correlation of the L-Arginine Pathway with Thrombo-Inflammation May Contribute to the Outcome of Acute Ischemic Stroke. | 27263035 |
| Ischemic stroke | Altered Intercellular Communication | Concentration of L-arginine and ADMA/SDMA differentially correlates with thrombo-inflammation in the hyperacute phase of ischemic stroke. | 27263035 |
| Inflammation, Disorder of tendon | Altered Intercellular Communication | We sought evidence of interleukin 17A (IL-17A) expression in early human tendinopathy and thereafter, explored mechanisms whereby IL-17A mediated inflammation and tissue remodeling in human tenocytes. | 27263531 |
| Communicable Diseases, Inflammation | Altered Intercellular Communication | Oncology (67%) and neurology/psychiatry (66%) were the most frequent target indications pursued by companies followed by inflammation (48%), cardiovascular (43%), metabolic (39%), infectious (37%), orphan (32%) and respiratory (29%) diseases. | 27263834 |
| Communicable Diseases, Inflammation, Fever, CTCAE | Altered Intercellular Communication | Fever in the intensive care unit (ICU) is usually an adaptive response to infection or inflammation. | 27264198 |
| ARCN1 gene, Inflammation, Asthma, Occupational | Altered Intercellular Communication | The aim of this study was to compare the sputum and serum markers of inflammation in patients with occupational asthma and COPD. | 27265531 |
| Renal Insufficiency, Inflammation, Chronic Kidney Diseases, Uremia | Altered Intercellular Communication | Chronic renal failure patients suffer from chronic inflammation that results from factors such as impaired renal function, accumulation of uremic toxins and bio incompatibility of dialyzer membranes. | 27267129 |
| Inflammation, Retinitis Pigmentosa, polychondritis, Collagen Diseases | Altered Intercellular Communication | Relapsing polychondritis (RP) is a rare rheumatologic disorder in which recurrent episodes of inflammation result in destruction of cartilage of the ears and nose. | 27267190 |
| Uremia, Inflammation | Altered Intercellular Communication | The response of erythropoietic stimulating agents (ESA) in uremic patients may be associated with the changes of biochemical parameters, metal elements and inflammation status during the shift from one ESA to another. | 27267426 |
| Inflammation | Altered Intercellular Communication | IRs had a significantly lower initial T-CHOL (p=0.03) and initial CRP (p=0.012) than non-responders, which may be related to lower inflammation. | 27267426 |
| Inflammatory abnormality of the eye | Altered Intercellular Communication | It seems to be safe to use 100% autologous serum despite earlier suspicions regarding immune complex accumulations and exacerbation of ocular surface inflammation. | 27267447 |
| Inflammation, Demyelination, Edema, Encephalomyelitis, Acute Disseminated | Altered Intercellular Communication | The underlying pathogenesis of ADEM may include perivascular inflammation, oedema and demyelination in the central nervous system. | 27268491 |
| Gingivitis, Inflammation, ETV3 wt Allele | Altered Intercellular Communication | Elevated levels of GCF RANTES in MetS patients with gingivitis might associate with the presence of increased gingival inflammation by MetS. | 27270225 |
| Inflammation, ETV3 wt Allele | Altered Intercellular Communication | Low-grade systemic inflammation associated with MetS and adipose tissue-derived RANTES might lead to altered GCF RANTES levels in the presence of gingival inflammation. | 27270225 |
| Heart Diseases, Inflammation | Altered Intercellular Communication | Adipose-derived adipokines have been demonstrated to be associated with the development of experimental heart disease through chronic inflammation and cardiac cell apoptosis. | 27270246 |
| Inflammation, Hostility | Altered Intercellular Communication | Hostility has been associated with higher basal levels of inflammation. | 27270459 |
| Inflammation | Altered Intercellular Communication | Such models would improve the ranking of candidates for liver transplantation by differentiating the severe patients with persistent systemic inflammation and intermediate MELD scores. | 27271159 |
| Degenerative polyarthritis | Altered Intercellular Communication | Our data support an anti-senescence and anti-inflammatory role for the C-terminal moiety of PTHrP with potential applications in chronic inflammatory conditions such as OA. | 27271252 |
| Inflammation, Myocardial, Atrial Fibrillation by ECG Finding | Altered Intercellular Communication | Radiofrequency catheter ablation versus balloon cryoablation of atrial fibrillation: markers of myocardial damage, inflammation, and thrombogenesis. | 27271554 |
| Inflammation, Chronic sinusitis | Altered Intercellular Communication | Natural killer cells regulate eosinophilic inflammation in chronic rhinosinusitis. | 27271931 |
| Inflammation, Impaired T cell function | Altered Intercellular Communication | This decrease was associated with NK cell dysfunction and eosinophilic inflammation. | 27271931 |
| eosinophil, Inflammation, Craniosynostosis | Altered Intercellular Communication | In a murine model of CRS, NK cell depletion caused an exacerbation of blood eosinophilia and eosinophilic inflammation in the sinonasal tissue. | 27271931 |
| Inflammation, Craniosynostosis | Altered Intercellular Communication | Thus, our results suggest decreased NK cell-mediated eosinophil regulation, possibly through an increased level of PGD2, as a previously unrecognized link between PG dysregulation and eosinophilic inflammation in CRS. | 27271931 |
| Myocarditis | Altered Intercellular Communication | Pericardial inflammation with reversible constriction: prediction of recovery with cardiovascular magnetic resonance. | 27271935 |
| Acne, Hyperandrogenism | Altered Intercellular Communication | As androgenic hormones play a very important role in the acne pathogenesis, the early diagnosis of hyperandrogenic states is very useful for the proper evaluation of each patient and for a better choice of therapeutic management. | 27272708 |
| Inflammation, Pain Distress Question | Altered Intercellular Communication | A new finding in the present work is a significant correlation in the NRS scale versus plasma concentrations of anti-inflammatory cytokine IL-10 and pro-inflammatory cytokine IL-1b postoperatively suggesting that inflammation and pain are related. | 27272818 |
| Inflammation, Neoplasms | Altered Intercellular Communication | In addition to their unfavorable role as mediators of evasion from antitumor immune response, Tregs might also have a beneficial role by reducing inflammation thereby limiting early tumor growth and spreading. | 27272839 |
| Inflammation, Peripheral Arterial Diseases | Altered Intercellular Communication | Association between gait characteristics and endothelial oxidative stress and inflammation in patients with symptomatic peripheral artery disease. | 27273077 |
| Inflammation | Altered Intercellular Communication | Abnormalities of mineral metabolism and inflammation may affect the cardiovascular system. | 27273357 |
| Left Ventricular Hypertrophy, Inflammation, Ventricular hypertrophy | Altered Intercellular Communication | We have assessed the relationship of left ventricular hypertrophy (LVH) with inflammation and mineral metabolism. | 27273357 |
| Inflammation, Asthma | Altered Intercellular Communication | AEs of cold, upper respiratory inflammation and asthmatic attack occurred in each of the 3 patients (8.6%); however, these were not regarded as treatment-related AEs. | 27273710 |
| Inflammation | Altered Intercellular Communication | The mechanism of action is unknown, but it may be mediated by inflammation. | 27274008 |
| Refractory anemias, Inflammation | Altered Intercellular Communication | Genetic markers of RA susceptibility located within HLA-DRB1 determine the levels of clinical and systemic inflammation independently, and also determine all objective measures of disease activity and outcome. | 27274008 |
| ARCN1 gene, Inflammation | Altered Intercellular Communication | Extracellular cadmium in the bronchoalveolar space of long-term tobacco smokers with and without COPD and its association with inflammation. | 27274222 |
| Steatohepatitis, Fibrosis Assessment, Inflammation | Altered Intercellular Communication | The degrees of liver steatosis, lobular inflammation and fibrosis were determined based on the non-alcoholic fatty liver activity score (NAS) by a single expert pathologist. | 27275102 |
| Steatohepatitis, Fibrosis Assessment, Inflammation | Altered Intercellular Communication | Receiver operating characteristic (ROC) analysis was employed to determine cut-off values of serum adipokines to discriminate the grades of liver steatosis, lobular inflammation and fibrosis. | 27275102 |
| Inflammation | Altered Intercellular Communication | Elevated serum IL-6 and IL-8 levels were associated independently with advanced lobular inflammation [b = 1.4 (95%CI: 1.09-1.8), 1.07 (95%CI: 1.003-1.15), P < 0.05]. | 27275102 |
| Inflammation | Altered Intercellular Communication | Xanthogranulomatous inflammation in the spinal epidural space is extremely rare. | 27276211 |
| Inflammation, Lymphoma | Altered Intercellular Communication | We report a case of a 62-year-old man with a xanthogranulomatous inflammation in the spinal epidural space mistaken for lymphoma because of its avid F FDG uptake on PET/CT. | 27276211 |
| Xanthogranulomatous inflammation | Altered Intercellular Communication | This case emphasizes the need for caution when evaluating a spinal epidural mass using F FDG PET/CT as xanthogranulomatous inflammation can induce a false-positive reading on F-FDG PET/CT. | 27276211 |
| Inflammation, Unspecified visual loss | Altered Intercellular Communication | A 75-year-old Asian male with bilateral phacoemulsification and intraocular lens implantation developed severe inflammation with sharp vision loss in both eyes after the surgeries. | 27277218 |
| Inflammation | Altered Intercellular Communication | After 5 days of medication, the inflammation was markedly relieved, and no recurrence was observed 2 weeks later. | 27277218 |
| Inflammation | Altered Intercellular Communication | These effects were attenuated following treatment with exogenous IGF1, thus indicating that the miR-206/IGF1 signaling pathway may be considered a novel therapeutic target for the treatment of AD-associated microglial inflammation. | 27277332 |
| Inflammation | Altered Intercellular Communication | Many chemical agents are tried to induce inflammation and damage of the pleural mesothelial layer to achieve this symphysis. | 27277376 |
| Inflammation, Immunocompromised Host, Necrotizing herpetic retinopathy | Altered Intercellular Communication | Necrotizing herpetic retinopathy in an immune-compromised pediatric patient with minimal signs of inflammation: case report. | 27277425 |
| Inflammation, Bronchopleural Fistula | Altered Intercellular Communication | Postoperative pyothorax (PP) following development of a bronchopleural fistula (BPF) after lung surgery induces continuous inflammation and may affect the occurrence of AE. | 27277761 |
| Cessation of life, Inflammation | Altered Intercellular Communication | Our second goal was to determine whether traumatic deaths with different survival times, septic deaths, and deaths in individuals suffering from diseases with significant systemic inflammation are systematically characterized by increased concentrations of total IgE in postmortem serum from femoral blood. | 27277898 |
| Inflammation, Fibrosis Assessment, Edema, Acute hepatitis, Cholestasis | Altered Intercellular Communication | Acoustic radiation force impulse (ARFI) imaging techniques were recently developed to measure liver fibrosis, but their specificity is impaired by cholestasis, inflammation, or edema in acute hepatitis. | 27277904 |
| Inflammation, Primary malignant neoplasm | Altered Intercellular Communication | Pentraxin 3 (PTX3) is an inflammatory molecule that is involved in immune responses, inflammation, and cancer. | 27278519 |
| Myositis, Edema, Fatty infiltration | Altered Intercellular Communication | It may identify muscle inflammation (edema) and fatty infiltration for evaluation of disease activity and damage. | 27279002 |
| Vasculitis, Prediabetes syndrome | Altered Intercellular Communication | The results support the beneficial effects of RO extract on the control of glycemia and vascular inflammation in prediabetic patients. | 27279471 |
| Inflammation | Altered Intercellular Communication | The typical histopathology is that of necrotizing granulomatous inflammation with palisading histiocytes, neutrophils, and lymphocytes. | 27279517 |
| Inflammation | Altered Intercellular Communication | LLRs are associated with a vaccine-specific IgE response and IP-10, whereas SRs demonstrate increased systemic inflammation without a skewed cytokine profile. | 27280620 |
| Inflammation, Malnutrition, Chronic Kidney Diseases | Altered Intercellular Communication | From 1994 to 2014, 543 patients with stage 5 CKD (median age =56 years old; 63% men; 199 patients had CVD) took part in our study on malnutrition, inflammation, and CVD in incident dialysis patients. | 27281698 |
| Inflammation, Cachexia | Altered Intercellular Communication | Protein energy wasting and systemic inflammation are prevalent in maintenance hemodialysis (MHD) patients. | 27281699 |
| Inflammation, Inflammatory disorder | Altered Intercellular Communication | Primary inclusion criteria included signs of chronic inflammation (average C-reactive protein of >=5 mg/L over three consecutive measurements), lack of active infectious or inflammatory disease, no hospitalization within 1 month prior to the study, and not receiving steroids (>5 mg/d) and/or immunosuppressive agents. | 27281699 |
| Inflammation | Altered Intercellular Communication | High-dose o-3 supplementation over 12 weeks in MHD patients with systemic inflammation was associated with attenuation of forearm muscle protein breakdown but did not influence skeletal muscle protein synthesis, skeletal muscle net protein balance or any component of the whole-body protein balance. | 27281699 |
| Diabetes Mellitus | Altered Intercellular Communication | Arterial Stiffness Is Positively Associated With 18F-fluorodeoxyglucose Positron Emission Tomography-Assessed Subclinical Vascular Inflammation in People With Early Type 2 Diabetes. | 27281773 |
| Arterial Stiffness, Inflammation, Diabetes Mellitus, Non-Insulin-Dependent | Altered Intercellular Communication | The possible relationship between subclinical arterial inflammation assessed by (18)F-fluorodeoxyglucose (FDG) positron emission tomography/computed tomography (PET/CT) and arterial stiffness was investigated in patients with early type 2 diabetes. | 27281773 |
| Arterial Stiffness, Diabetes Mellitus, Non-Insulin-Dependent, Arteritis | Altered Intercellular Communication | In patients with type 2 diabetes, FDG-PET/CT-imaged subclinical arterial inflammation is positively associated with determinants of arterial stiffness. | 27281773 |
| Conn Adenoma | Altered Intercellular Communication | Expression of inflammation-related genes in aldosterone-producing adenomas with KCNJ5 mutation. | 27282482 |
| Inflammation, Non-Small Cell Lung Carcinoma | Altered Intercellular Communication | Cytokine-mediated inflammation is important in the pathogenesis of non-small cell lung cancer (NSCLC). | 27282611 |
| Inflammation, Asthma | Altered Intercellular Communication | The presence of eosinophilic (type 2) inflammation in some but not all patients with severe asthma predicts responsiveness to current treatments, but new treatment approaches will require a better understanding of non-type 2 mechanisms of severe asthma. | 27283230 |
| Inflammation, Asthma | Altered Intercellular Communication | We considered the possibility that systemic inflammation, which arises in subgroups of obese and older patients, increases the severity of asthma. | 27283230 |
| Inflammation, Asthma, physiopathological | Altered Intercellular Communication | Interleukin-6 (IL-6) is a biomarker of systemic inflammation and metabolic dysfunction, and we aimed to explore the association between IL-6 concentrations, metabolic dysfunction, and asthma severity. | 27283230 |
| Inflammation, Asthma, physiopathological | Altered Intercellular Communication | Systemic IL-6 inflammation and clinical features of metabolic dysfunction, which occur most commonly in a subset of obese asthma patients but also in a small subset of non-obese patients, are associated with more severe asthma. | 27283230 |
| Inflammation | Altered Intercellular Communication | Lipid accumulation and chronic inflammation occur in the sIA wall. | 27283327 |
| PROS1 gene, Arthritis, Psoriatic, Psoriasis | Altered Intercellular Communication | Psoriatic arthritis (PsA) is a potentially severe inflammatory condition (entheso-arthro-osteopathy), and early diagnosis is important to guide treatment choices in patients with psoriasis. | 27283499 |
| Stomach Carcinoma | Altered Intercellular Communication | Systemic immune-inflammation index, thymidine phosphorylase and survival of localized gastric cancer patients after curative resection. | 27283904 |
| Inflammation, Calcinosis | Altered Intercellular Communication | Osteopontin (OPN) is a secreted glycophosphoprotein that has a role in inflammation, immune response and calcification. | 27284698 |
| Inflammation | Altered Intercellular Communication | In addition the decreased IGF-I serum levels may affect the modulation of inflammation and lesion healing in chronic phase. | 27286813 |
| Inflammation, Menopause | Altered Intercellular Communication | Exploring Black-White Differences in the Relationship Between Inflammation and Timing of Menopause. | 27287275 |
| Inflammation | Altered Intercellular Communication | Prior research on inflammatory chronic conditions suggests that inflammation may predict how early women experience menopause. | 27287275 |
| Communicable Diseases, Inflammation | Altered Intercellular Communication | The hs-CRP levels associated with HS appear to be intermediate (2.2-5.1 mg/l), implying systemic inflammation rather than infection. | 27287331 |
| Inflammation, Tuberculosis, Pulmonary | Altered Intercellular Communication | They were analysed for response to DLCP in terms of IOP control, vision-related complications, increased inflammation, post-trabeculectomy hypotony and chances of phthisis and ciliary shutdown. | 27287344 |
| Inflammation, Ocular Hypotension, Suprachoroidal hemorrhage | Altered Intercellular Communication | There were no other complications like increased inflammation, prolonged hypotony or suprachoroidal haemorrhage. | 27287344 |
| Diverticulosis, Inflammation, Diverticulitis, Malignant Neoplasms | Altered Intercellular Communication | Of the patients with CT scans suggestive of diverticulitis, follow-up colonoscopy showed 3 with diverticulosis, 2 with malignancies, and 1 with nonspecific inflammation. | 27287835 |
| Inflammation, Injury of liver | Altered Intercellular Communication | Lipocalin 2 (LCN2) is induced in the injured liver and associated with inflammation. | 27288631 |
| Inflammation, Cardiovascular Diseases | Altered Intercellular Communication | Characteristics of daily social interactions among midlife and older adults associate with markers of systemic inflammation that are known to predict risk for cardiovascular disease. | 27288715 |
| Inflammation, Infection by Cryptococcus neoformans, Nocardia Infections, Tuberculosis, Zygomycosis, Mycobacterium Infections | Altered Intercellular Communication | The most common cytological diagnosis was mucormycosis (n = 13) followed by nocardiosis (n = 8) and necrotising inflammation (n = 7), tuberculosis (n = 6), cryptococcosis (n = 2), aspergillosis(n = 2), histoplasmosis(n = 1) and atypical mycobacterial infection (n = 1). | 27292015 |
| Inflammatory cardiomyopathy, Myocarditis | Altered Intercellular Communication | Endomyocardial miR-133a levels correlate with myocardial inflammation, improved left ventricular function, and clinical outcome in patients with inflammatory cardiomyopathy. | 27292200 |
| Inflammation, Heart failure | Altered Intercellular Communication | A set of six microRNAs implicated in inflammation (miR-155 and miR-146b), heart failure (miR-21 and miR-133a), and endothelial cell (miR-126) and skeletal muscle function (miR-206) was pre-defined. | 27292200 |
| Inflammation, Pneumoconiosis | Altered Intercellular Communication | The association between pneumoconiosis and coal mine dust contiguity is thought to be due to the effect of coal dust by producing chronic inflammation. | 27292375 |
| Inflammation | Altered Intercellular Communication | In this study, ocular findings suggest that systemic levels of trace elements and chronic inflammation may not reach to a level that influences ocular structures. | 27292375 |
| AUTOIMMUNE DISEASE, MULTISYSTEM, INFANTILE-ONSET, 1, Retinitis Pigmentosa, polychondritis, Inflammation | Altered Intercellular Communication | Relapsing polychondritis (RP) is a rare, multisystem autoimmune disease characterized by inflammation, structural damage, and impaired function of cartilaginous tissues throughout the body. | 27292528 |
| Refractory anemias, Rheumatoid Arthritis, Arthritis, Autoimmune Diseases | Altered Intercellular Communication | Rheumatoid arthritis (RA) is a systemic autoimmune disease with chronic joint inflammation characterized by activated T cells. | 27294146 |
| Inflammation | Altered Intercellular Communication | Coenzyme Q10 (CoQ10) deficiency has been associated with statin-induced myopathy, and supplementation with CoQ10 may reduce inflammation markers. | 27294339 |
| Vascular Diseases, Inflammation | Altered Intercellular Communication | Relationships between CoQ10, subclinical vascular disease, and biomarkers of inflammation and immune activation were explored using Spearman correlations and multivariable regression models. | 27294339 |
| Inflammatory Bowel Diseases, Rheumatoid Arthritis, Lymphoproliferative Disorders, "wegeners granuloma", vascular inflammations, Lupus Erythematosus | Altered Intercellular Communication | There are reported cases of coexistence with systemic lupus erythematosus, rheumatoid arthritis, Wegener's granuloma, inflammatory bowel disease, generalized vascular inflammation, and lymphoproliferative disorders. | 27294654 |
| Vasculitis, Leukocytoclastic, Cutaneous, Granulomatous inflammation | Altered Intercellular Communication | It is probable that the deposition of immune complexes in blood vessels leads to cutaneus leukocytoclastic vasculitis, degeneration of collagen fibres and palisaded granulomatous inflammation. | 27294654 |
| Inflammation, Breast Carcinoma | Altered Intercellular Communication | Inflammation may play a role in breast cancer, but evidence in the general population is lacking. | 27294662 |
| Inflammation, Primary malignant neoplasm, Obesity | Altered Intercellular Communication | Our findings support a role of inflammation in BCa mortality which may involve mechanisms apart from obesity, and potential usefulness of GLR as a marker in assessing inflammation and cancer. | 27294662 |
| Inflammation, Malabsorption Syndrome, physiopathological, Growth Disorders | Altered Intercellular Communication | Environmental enteric dysfunction, an asymptomatic condition characterized by inflammation of the small bowel mucosa, villous atrophy, malabsorption, and increased intestinal permeability, is a major contributor to childhood stunting in low-income countries. | 27294788 |
| Inflammation, Carotid Atherosclerosis | Altered Intercellular Communication | Galectin-3 binding protein (Gal-3BP) is a secreted protein associated with inflammation and carotid atherosclerosis. | 27295060 |
| Inflammation, Thrombosis, diabetic | Altered Intercellular Communication | The cold effects on circulatory inflammation, thrombosis and vasoconstriction in type 2 diabetic patients. | 27295598 |
| Inflammation, Observation Method - Coagulation | Altered Intercellular Communication | We aimed to examine the associations between ambient temperature and circulating biomarkers of inflammation, coagulation and vasoconstriction. | 27295598 |
| Inflammation, Observation Method - Coagulation | Altered Intercellular Communication | Sixteen biomarkers of inflammation, coagulation and vasoconstriction were repeatedly measured over six follow-ups. | 27295598 |
| Inflammation | Altered Intercellular Communication | Chronic systemic inflammation contributes to the development of adverse health conditions, yet the influence of fixed and modifiable risk factors on many serologic biomarkers of inflammation remains largely unknown. | 27295613 |
| Inflammation, "Alzheimers Disease | Altered Intercellular Communication | Oxidative stress and inflammation are associated with physical frailty in patients with Alzheimer's disease. | 27296166 |
| Inflammation, Data types - Address | Altered Intercellular Communication | The present results strongly suggest that oxidative stress and inflammation are involved in the pathophysiology of frailty status in individuals with AD. | 27296166 |
| Inflammation, Malignant Neoplasms | Altered Intercellular Communication | All lesions were histologically or clinically confirmed (malignancy: inflammation = 24:20). | 27298058 |
| Liver carcinoma | Altered Intercellular Communication | Preoperative inflammation-based markers predict early and late recurrence of hepatocellular carcinoma after curative hepatectomy. | 27298102 |
| FAM126A gene | Altered Intercellular Communication | Preoperative inflammation-based prognostic factors predict early and late recurrence of HCC after curative resection. | 27298102 |
| Malaria, Falciparum, Prediabetes syndrome, Obesity, diabetic | Altered Intercellular Communication | Increased Oxidative Stress and Inflammation Independent of Body Adiposity in Diabetic and Nondiabetic Controls in falciparum Malaria. | 27298824 |
| Malaria, Falciparum, Inflammation, Diabetes Mellitus, Non-Insulin-Dependent | Altered Intercellular Communication | Information on the extent to which oxidative stress and inflammation occur in the presence of falciparum malaria and type 2 diabetes mellitus in the same individual is limited. | 27298824 |
| Malaria, Falciparum, Inflammation | Altered Intercellular Communication | Uncomplicated falciparum malaria elevated inflammation and peroxidation but decreased antioxidant power independent of adiposity. | 27298824 |
| Inflammation, Thrombocytopenia, Extravasation, Puumala virus | Altered Intercellular Communication | Thrombocytopenia associates with the severity of inflammation and variables reflecting capillary leakage in Puumala Hantavirus infection, an analysis of 546 Finnish patients. | 27299174 |
| Acute Kidney Injury, CTCAE, Inflammation, Extravasation, Thrombocytopenia | Altered Intercellular Communication | The severity of thrombocytopenia associates with the degree of inflammation and variables reflecting capillary leakage, but not with the severity of acute kidney injury in PUUV infected Finnish patients. | 27299174 |
| Inflammatory disease of mucous membrane | Altered Intercellular Communication | Viscous formulation increases mucosal contact time resulting in a greater decrease in mucosal inflammation. | 27299595 |
| Primary malignant neoplasm | Altered Intercellular Communication | Systemic and local inflammations have been described as relevant prognostic factors in patients with cancer. | 27300446 |
| Inflammation, Ulcerative Colitis, Hepatobiliary Disorder, Fibrosis, Liver, Carcinogenic Chlorinated Hydrocarbon, How Much Bothered by Arm Heaviness in Affected Arm | Altered Intercellular Communication | Determining the level of TNFa allows to evaluate the severity of liver disease, heaviness and progression of liver fibrosis speed in CHC, and the severity of inflammation in the intestinal mucosa in UC. | 27301136 |
| Fibrosis Assessment, Heart failure, Myocarditis | Altered Intercellular Communication | Galectin-3 is a marker of myocardial inflammation and fibrosis shown to correlate with morbidity and mortality in heart failure (HF). | 27301475 |
| Leukoencephalopathy, Inflammation, Leukoencephalopathy, Progressive Multifocal | Altered Intercellular Communication | We diagnosed progressive multifocal leukoencephalopathy (PML) with controlled inflammation. | 27301518 |
| Inflammation, Fibrosis Assessment, Liver Cirrhosis | Altered Intercellular Communication | Biopsy specimens with less fibrosis and/or mild portal inflammation showed significantly more staining than those with cirrhosis (P < 0.001), or at least moderate inflammatory activity (P < 0.001). | 27302660 |
| Inflammation | Altered Intercellular Communication | There was no significant association between lobular inflammation (P = 0.06), bilirubin levels or viral load and immunohistochemical staining for serum amyloid A. | 27302660 |
| Small cell carcinoma of lung, Adrenal cortical hypofunction | Altered Intercellular Communication | According to low levels of serum cortisol, elevated adrenocorticotropic hormone (ACTH) and rapid ACTH test, the diagnosis of adrenal insufficiency associated with SCLC was made. | 27302729 |
| Myelofibrosis, Inflammation, Molecular Abnormality | Altered Intercellular Communication | Along with molecular abnormalities (mutations in JAK2, Calreticulin (CALR) and MPL genes), chronic inflammation is the major hallmark of Myelofibrosis (MF). | 27304059 |
| Inflammation, Dysplasia | Altered Intercellular Communication | However, severe inflammation may induce reactive epithelial cell changes and hence mimic histologic dysplasia. | 27305938 |
| Communicable Diseases, Inflammation, Craniosynostosis | Altered Intercellular Communication | In a population of CRS patients with active infection or inflammation, we sought to determine if a correlation between T2R38 phenotype and in vitro biofilm formation existed. | 27309535 |
| Inflammation, Hyperintensity of cerebral white matter on MRI | Altered Intercellular Communication | To examine associations between inflammation and physical function and potential mediation by white matter hyperintensities (WMHs) in African Americans (AAs) and European Americans (EAs). | 27310030 |
| Inflammation, Microvascular Angina | Altered Intercellular Communication | Inflammation may contribute to physical function impairments through pathways other than brain microvascular disease, particularly in AAs. | 27310030 |
| Inflammation | Altered Intercellular Communication | This implied that leukocyte migration and inflammation cascade activation might contribute to frailty, in addition to monocyte/macrophage-mediated immuno-inflammation. | 27310835 |
| Inflammation, Metabolic Syndrome X | Altered Intercellular Communication | Adjustment for left ventricular morphology, metabolic syndrome, and systemic inflammation was also performed. | 27311062 |
| Inflammation, Metabolic Syndrome X | Altered Intercellular Communication | Associations were unchanged when accounting for health behaviors, markers of systemic inflammation, and the metabolic syndrome. | 27311062 |
| Inflammation, Fibrosis Assessment | Altered Intercellular Communication | However, currently ST2 (member of the interleukin 1 receptor family) has emerged as marker of inflammation, fibrosis and cardiac stress. | 27311068 |
| Chorioretinitis, Inflammation, Toxoplasmosis | Altered Intercellular Communication | Inflammation due to retinal neuroepithelial necrotic granulomas of toxoplasmosis can extend to neighbor areas and may develop focal adhesions of the posterior hyaloid, to the surface vessels, and the margins or adjoining areas of retinochoroiditis plaques. | 27312206 |
| Inflammation, Chronic Kidney Diseases | Altered Intercellular Communication | Further research is needed to understand the roles that CRP and systemic inflammation play in CKD risk. | 27312245 |
| Airway structure | Altered Intercellular Communication | Eighty-seven subjects (9.6%) had incidental findings that required further investigation, 42 (4.6%) from lower airways inflammation. | 27312516 |
| Upper Respiratory Infections | Altered Intercellular Communication | Clinically important incidental findings were found in 9.4%, predominantly related to lower respiratory tract inflammation. | 27312516 |
| Inflammation, Atherosclerosis | Altered Intercellular Communication | High-density lipoprotein (HDL)-bound paraoxonase-1 (PON-1) is mechanistically related to oxidative stress, inflammation and atherosclerosis and this multirole nature positions the enzyme as potential pathogenic player and candidate biomarker for many diseases. | 27312742 |
| Inflammation, Unipolar Depression | Altered Intercellular Communication | There is mixed evidence in the literature on the role of inflammation in major depressive disorder. | 27313138 |
| Depressive disorder, Inflammation | Altered Intercellular Communication | Our well-characterized examination of cytokine plasma levels did not support the association of major depressive disorder with systemic inflammation. | 27313138 |
| Gastrointestinal inflammation | Altered Intercellular Communication | Platelet interaction with lymphatics aggravates intestinal inflammation by suppressing lymphangiogenesis. | 27313177 |
| Inflammation, Colitis | Altered Intercellular Communication | Our data suggest that despite elevated lymphangiogenic factors during colonic inflammation, platelet migration to LVs resulted in suppressed lymphangiogenesis, leading to aggravation of colitis by blocking the clearance of inflammatory cells. | 27313177 |
| Inflammation | Altered Intercellular Communication | Sensory evoked potentials suggested proximal demyelination and lumbosacral plexus imaging suggested inflammation. | 27313227 |
| TG gene, Inflammation | Altered Intercellular Communication | Plasma periostin levels were strongly associated with plasma TG, chronic inflammation, and insulin resistance. | 27313402 |
| ARCN1 gene, Inflammation, Chronic Obstructive Airway Disease | Altered Intercellular Communication | Chronic obstructive pulmonary disease (COPD) is characterized by chronic inflammation in the airway and lung. | 27313452 |
| Inflammation, Stomach Carcinoma, Malignant Neoplasms | Altered Intercellular Communication | Inflammation and hormonal signalling induce the cyclooxygenase-2 (COX-2) expression in various human cancers including Gastric Cancer (GC). | 27314294 |
| Inflammation, Stomach Carcinoma, Malignant Neoplasms | Altered Intercellular Communication | Inflammation and hormonal signalling induce the cyclooxygenase-2 (COX-2) expression in various human cancers including Gastric Cancer (GC). | 27314294 |
| Inflammation, Stomach Carcinoma, Malignant Neoplasms | Altered Intercellular Communication | Inflammation and hormonal signalling induce the cyclooxygenase-2 (COX-2) expression in various human cancers including Gastric Cancer (GC). | 27314294 |
| Alzheimers Disease", Data types - Address, Penile Diseases | Altered Intercellular Communication | Moreover, current knowledge on brain monoaminergic neurotransmitter deficiencies in this presenile disorder is scarce, particularly with reference to changes in Alzheimer's disease (AD). | 27314528 |
| Inflammation, Microbial Biofilms, Presenile dementia, Chronic infectious disease, Data types - Address | Altered Intercellular Communication | Spirochetes evade host defenses, locate intracellularly, form more resistant atypical forms and notably biofilms, which contribute to sustain chronic infection and inflammation and explain the slowly progressive course of dementia in AD. | 27314530 |
| Psoriatic Juvenile Idiopathic Arthritis, Inflammation, Psoriasis | Altered Intercellular Communication | Treatment with phototherapy in patients with psoriasis may affect systemic inflammation by downregulation of the expression of genes encoding proinflammatory cytokines in PBMCs, implicated in the development of psoriasis and psoriatic comorbidities. | 27314537 |
| Atherosclerosis | Altered Intercellular Communication | Atherosclerosis is a pro-inflammatory condition, in which leucocyte activation plays an important role. | 27314629 |
| Inflammation | Altered Intercellular Communication | Based on these results, CIRP mediates inflammation and is a potential marker for synovial inflammation. | 27315340 |
| Pneumonitis, Eosinophilic inflammation | Altered Intercellular Communication | In mice inhalation of SplD without adjuvant induced lung inflammation characterized by TH2 cytokines and eosinophil infiltration. | 27315768 |
| Inflammation, Spinal Cord Injuries, Neuralgia | Altered Intercellular Communication | Targeting inflammation as a treatment modality for neuropathic pain in spinal cord injury: a randomized clinical trial. | 27316678 |
| Inflammation, Biliary calculi | Altered Intercellular Communication | However, on review by two different multidisciplinary teams, the final conclusion was probable residual gallstones with associated inflammation. | 27317757 |
| Inflammation, Malnutrition, Congestive heart failure | Altered Intercellular Communication | These observations support the complex involvement of malnutrition and inflammation in the pathogenesis of CHF. | 27317841 |
| Inflammation, Brain Injuries | Altered Intercellular Communication | Resveratrol attenuates peripheral and brain inflammation and reduces ischemic brain injury in aged female mice. | 27318135 |
| Infarction, Inflammation, Ischemic stroke | Altered Intercellular Communication | Mice treated with resveratrol demonstrated smaller infarct size, improved neurological function, and blunted peripheral inflammation at 3 days postischemic stroke. | 27318135 |
| Inflammation, Brain Injuries | Altered Intercellular Communication | These results showed that resveratrol counteracted inflammation in visceral adipose tissue and in the brain and reduced stroke-induced brain injury and peripheral inflammation in aged female mice. | 27318135 |
| Inflammation, AAVS1 gene, Vasculitis, CTCAE | Altered Intercellular Communication | Anti-neutrophil cytoplasmic antibody (ANCA) -associated vasculitis (AAV) is a disease characterized by inflammation of small vessels and detectable ANCA in the circulation. | 27318367 |
| Inflammation, Primary malignant neoplasm | Altered Intercellular Communication | Stromal spindle cells such as fibroblasts are major components of tissue inflammation and tertiary lymphoid structures within the microenvironment that contribute to the survival and growth of cancer cells. | 27318497 |
| Inflammatory Bowel Diseases, Inflammation, gastrointestinal | Altered Intercellular Communication | Gastrointestinal and extraintestinal malignancies are long-term complications in patients with inflammatory bowel disease (IBD), likely as a result of chronic inflammation and the use of immunosuppressive medications used to control inflammation. | 27318857 |
| Inflammation | Altered Intercellular Communication | The impact of TREM-1-mediated inflammation was investigated in different inflammatory settings. | 27319606 |
| Sepsis, Communicable Diseases, Inflammation, Systemic Inflammatory Response Syndrome | Altered Intercellular Communication | Systemic inflammation in humans may be triggered by infection, termed sepsis, or non-infective processes, termed non-infective systemic inflammatory response syndrome (SIRS). | 27320175 |
| Sepsis, Systemic Inflammatory Response Syndrome | Altered Intercellular Communication | Levels of these 'circulating inflammation-related microRNAs' (CIR-miRNAs) were 2.64 (IQR: 2.10-3.29) and 1.52 (IQR: 1.15-1.92) fold higher for non-infective SIRS and sepsis respectively (p < 0.0001), hence CIR-miRNAs appeared less abundant in sepsis than in SIRS. | 27320175 |
| Inflammation | Altered Intercellular Communication | CIR-miRNAs may be regulators of inflammation and warrant thorough evaluation as diagnostic and therapeutic targets. | 27320175 |
| Gingivitis, Chief complaint (finding) | Altered Intercellular Communication | The patient was a 66-year-old man who presented with the chief complaint of gingival inflammation and mobile teeth in the molar region. | 27320299 |
| Inflammation, Dental Plaque | Altered Intercellular Communication | Baseline examination revealed generalized plaque deposition and gingival inflammation. | 27320300 |
| palladium, Inflammation | Altered Intercellular Communication | After reducing inflammation and subgingival bacteria, open flap debridement was performed for teeth with a PD of >=4 mm. | 27320300 |
| ARCN1 gene, Inflammation | Altered Intercellular Communication | Acute exercise amplifies inflammation in obese patients with COPD. | 27320704 |
| ARCN1 gene, Inflammation, Chronic Obstructive Airway Disease | Altered Intercellular Communication | Systemic inflammation has been implicated in the pathogenesis of chronic obstructive pulmonary disease (COPD) systemic effects. | 27320704 |
| ARCN1 gene, Inflammation, Exacerbation | Altered Intercellular Communication | However, most COPD patients do not suffer from persistent systemic inflammation even after exacerbations and exercise and scientific evidence has provided conflicting results. | 27320704 |
| ARCN1 gene, Inflammation, Obesity | Altered Intercellular Communication | This preliminary study did not show an enhanced inflammatory gene expression from rest to 1h and 24h after short-term exercise, but did show an increased inflammatory gene expression in both BMI extremes, both at rest and after exercise, suggesting not only malnourishment, but also obesity as potential links between COPD and systemic inflammation. | 27320704 |
| Inflammation, Atherosclerosis | Altered Intercellular Communication | The biochemical parameters for glucose metabolism, inflammation and atherosclerosis were determined. | 27321876 |
| Inflammation, physiopathological | Altered Intercellular Communication | Environmental enteric dysfunction (EED), a clinically asymptomatic condition characterized by inflammation of the small bowel mucosa, villous atrophy, and increased gut permeability, is common among children in developing countries. | 27322559 |
| Myositis | Altered Intercellular Communication | Our results indicate that osmolyte pathways may contribute to normal muscle functioning, and that activation of AR, TauT, and SMIT in muscle inflammation possibly contributes to the tissue's failing program of damage control. | 27322952 |
| Neoplasms, Cardiovascular Diseases | Altered Intercellular Communication | Final cytological and histological diagnoses were divided into 6 main diagnostic groups: normal, neoplasms (benign and malignant), inflammatory conditions, adaptive processes, degeneration, and cardiovascular disorders. | 27322966 |
| Chronic liver disease, Lymphoproliferative Disorder of the Skin, Necrosis with inflammation | Altered Intercellular Communication | Angiogenesis is generally induced in the process of necro-inflammation and regeneration in chronic liver diseases (CLD). | 27323788 |
| Inflammation, Colorectal Carcinoma, Dysbiosis | Altered Intercellular Communication | In conclusion, F. nucleatum, B. fragilis and F. prausnitzii can be identified as useful prognostic biomarkers for CRC, and dysbiosis might worsen the patients' prognosis by up-regulating gut inflammation level. | 27323816 |
| Malignant neoplasm of urinary bladder | Altered Intercellular Communication | Hormonal factors may play a role in bladder cancer (BCa). | 27324053 |
| Inflammation, Spinal Cord Injuries | Altered Intercellular Communication | Targeting inflammation to influence cognitive function following spinal cord injury: a randomized clinical trial. | 27324320 |
| Inflammation, Hippocampus (Brain) | Altered Intercellular Communication | Alternatively, as these participants likely underwent years of previous chronic inflammation, the underlying hippocampal damage may have negated potential improvements induced by acute reductions in inflammation. | 27324320 |
| Inflammation, Arthritis, Rheumatoid Arthritis | Altered Intercellular Communication | Ultrasound-detected subclinical inflammation was better reflected by the disease activity score (DAS-28) in patients with suspicion of inflammatory arthritis compared to established rheumatoid arthritis. | 27325125 |
| Refractory anemias, Inflammation, palladium, Superficial ulcer | Altered Intercellular Communication | Patients with RA in clinical remission had significantly more active inflammation and erosions on US when compared with patients with S-IA with similar disease scores (p = 0.03 and p = 0.01, respectively); however, RA patients with different disease activity score (DAS-28) scores had similar PD scores (p = 0.058). | 27325125 |
| Refractory anemias, Inflammation, Disease | Altered Intercellular Communication | Subclinical inflammation is more common in patients with RA in clinical remission or with low disease activity than in patients with S-IA; therefore, US was more useful in assessing for true remission in RA rather than diagnosing IA in patients with low disease activity scores. | 27325125 |
| Inflammation | Altered Intercellular Communication | Further research into validating this model can minimise the risk of underdiagnosing subclinical inflammation. | 27325125 |
| Peripheral zone of prostate, Prostate carcinoma | Altered Intercellular Communication | Peripheral Zone Inflammation Is Not Strongly Associated With Lower Urinary Tract Symptom Incidence and Progression in the Placebo Arm of the Prostate Cancer Prevention Trial . | 27325488 |
| Inflammation, Lower Urinary Tract Symptoms | Altered Intercellular Communication | Intraprostatic inflammation has been associated with lower urinary tract symptom (LUTS) progression. | 27325488 |
| Inflammation, Lower Urinary Tract Symptoms | Altered Intercellular Communication | We, therefore, evaluated inflammation and LUTS incidence and progression in men who underwent biopsy of the prostate peripheral zone irrespective of indication. | 27325488 |
| Inflammation | Altered Intercellular Communication | Inflammation prevalence in low cases (64%) was similar to controls (66%), but higher in moderate (69%) and high (73%) cases (P-trend = 0.4). | 27325488 |
| Inflammation, Lower Urinary Tract Symptoms | Altered Intercellular Communication | Peripheral zone intraprostatic inflammation is not strongly associated with LUTS incidence or progression. | 27325488 |
| Inflammation, Thrombophilia | Altered Intercellular Communication | Associations were not mediated by circulating levels of studied biomarkers suggesting that body size relates to VT because of physical factors associated with blood flow, not the hypercoagulability or inflammation associated with adiposity. | 27328432 |
| Inflammation, Hepatic Infection | Altered Intercellular Communication | The roles of TREM1 and sTREM1 in liver infection and inflammation are not clear. | 27328755 |
| Hepatitis | Altered Intercellular Communication | Trem1-/- mice showed accelerated clearance of LCMV-WE and manifested attenuated liver inflammation and injury. | 27328755 |
| Inflammation, Fibrosis Assessment, Complete atrioventricular block, Hepatitis B | Altered Intercellular Communication | A retrospective study to determine the relationships between platelet parameters and inflammation and fibrosis of the liver in patients with chronic hepatitis B virus infection (CHB). | 27329384 |
| Inflammation, Fibrosis Assessment | Altered Intercellular Communication | Liver fibrosis and inflammation were assessed by histopathology of biopsied liver tissue. | 27329384 |
| Inflammation, Fibrosis Assessment | Altered Intercellular Communication | The relationship between inflammation and fibrosis and platelet parameters were analysed by multiple linear regression. | 27329384 |
| Hepatitis | Altered Intercellular Communication | PLT and PDW accounted for 20.5% of liver inflammation. | 27329384 |
| Fibrosis Assessment, Hepatic inflammation | Altered Intercellular Communication | Platelet parameters can provide valuable information for the assessment of hepatic inflammation and fibrosis. | 27329384 |
| Rheumatoid Arthritis, Arteritis | Altered Intercellular Communication | Influence of triple disease modifying anti-rheumatic drug therapy on carotid artery inflammation in drug-naive patients with recent onset of rheumatoid arthritis. | 27330160 |
| Refractory anemias, vascular inflammations, Atherosclerosis | Altered Intercellular Communication | Increased atherosclerosis in RA is not fully explained by the ordinary risk factors, but it may be related to vascular inflammation. | 27330160 |
| Refractory anemias, Arteritis | Altered Intercellular Communication | (18)F-FDG-PET/CT revealed that drug-naive patients with early RA show carotid artery inflammation that can be efficiently reduced by 1-month DMARD triple therapy. | 27330160 |
| Inflammation | Altered Intercellular Communication | Inflammation plays a major role in RD development after KPro implantation. | 27330474 |
| Inflammation | Altered Intercellular Communication | An association between gender, oxidative stress, and inflammation signaling exists, leading to a renewed interest in the neonate's sex as a potential risk factor to several alterations. | 27331351 |
| Immunologic Deficiency Syndromes, Granulomatous inflammation, Chronic granulomatous disease, Infection | Altered Intercellular Communication | Chronic granulomatous disease is a rare, inherited immunodeficiency disorder that reduces the superoxide generation ability of phagocytes, leading to recurrent infections and granulomatous inflammation. | 27331854 |
| Sjogrens Syndrome | Altered Intercellular Communication | Epigenetic Signatures of Salivary Gland Inflammation in Sjogren's Syndrome. | 27332624 |
| Inflammation, Atrophic | Altered Intercellular Communication | Histological neutrophil activity, chronic inflammation and atrophy scores were lower in group A' than in other groups. | 27332718 |
| Sepsis, Communicable Diseases | Altered Intercellular Communication | It also distinguished infection from trauma-related inflammation in the same patient cohorts with a higher specificity than the clinical sepsis biomarker, C-reactive Protein. | 27333027 |
| Arthritis, Dysbiosis | Altered Intercellular Communication | Autoreactive SKG mouse T cells are activated by dysbiotic microbiota in the intestine, causing joint inflammation. | 27333153 |
| Dermatitis, Atopic, Eyelid malposition, Inflammation, Lacrimation | Altered Intercellular Communication | Allergic dermatitis is a common but often misdiagnosed condition that can present with a variety of findings including inflammation, eyelid malposition, and tearing. | 27333449 |
| Inflammation | Altered Intercellular Communication | Topical corticosteroids often facilitate resolution of the associated inflammation. | 27333449 |
| ARCN1 gene, Inflammation, Chronic Obstructive Airway Disease, Lung diseases | Altered Intercellular Communication | Chronic obstructive pulmonary disease (COPD) is a progressive pulmonary disease characterized by systemic inflammation. | 27333717 |
| Inflammation, neurological disability, Nerve Degeneration | Altered Intercellular Communication | Inflammation is tightly linked with neurodegeneration, and it is the accumulation of neurodegeneration that underlies increasing neurological disability in progressive MS. | 27333900 |
| Infection caused by Helicobacter pylori, Duodenal Diseases | Altered Intercellular Communication | Polymorphisms in inflammation-related genes are factors associated with the development of gastroduodenal diseases in Helicobacter pylori-infected individuals. | 27334226 |
| Inflammation, Metabolic Syndrome X, ETV3 wt Allele | Altered Intercellular Communication | The impact of metabolic syndrome (MetS) associated systemic inflammation on the male reproductive tract requires further investigation. | 27334450 |
| Inflammation, ETV3 wt Allele | Altered Intercellular Communication | The results suggest that MetS is associated with decreased fertility parameters in males, as well as local reproductive tract inflammation, in the absence of leukocytospermia. | 27334450 |
| Inflammatory Bowel Diseases, Bacterial Infections, Gastrointestinal inflammation | Altered Intercellular Communication | Fecal calprotectin (fc) is a sensitive marker of intestinal inflammation, found to be associated with enteric bacterial infections and inflammatory bowel disease. | 27334992 |
| Inflammation | Altered Intercellular Communication | Our results suggest that exposure to pollutants with high oxidative potential (traffic-related pollutants, ultrafine particles, and transition metals) may lead to increased airway oxidative stress and inflammation in elderly adults. | 27336235 |
| Obesity | Altered Intercellular Communication | Does Inflammation Mediate the Obesity and BPH Relationship? | 27336586 |
| Obesity, prostatitis | Altered Intercellular Communication | Our objective was to investigate biomarkers of systemic and prostate tissue inflammation as potential mediators of the obesity and BPH association. | 27336586 |
| Inflammation, Lower Urinary Tract Symptoms, prostatitis | Altered Intercellular Communication | In contrast, the severity of prostate tissue inflammation was significantly associated with LUTS, such that there was a 7 point difference in AUA-SI between men with mild vs. severe inflammation (p = 0.004). | 27336586 |
| Lower Urinary Tract Symptoms, prostatitis | Altered Intercellular Communication | Additionally, men with a greater waist-hip ratio (WHR) were significantly more likely to have severe prostate tissue inflammation (p = 0.02), and a high WHR was significantly associated with moderate/severe LUTS (OR = 2.56, p = 0.03) among those participants with prostate tissue inflammation. | 27336586 |
| Inflammation, Lower Urinary Tract Symptoms, Obesity | Altered Intercellular Communication | The WHR, an estimate of centralized obesity, was associated with the severity of inflammatory regions in prostate tissue and with LUTS severity among men with inflammation. | 27336586 |
| Inflammation, Increase, Obesity | Altered Intercellular Communication | Our results suggest centralized obesity advances prostate tissue inflammation to increase LUTS severity. | 27336586 |
| Inflammation, altretamine/doxorubicin/melphalan protocol, Tropical Spastic Paraparesis | Altered Intercellular Communication | Five to ten million persons, are infected by HTLV-1 of which 3% will develop HTLV-1-associated myelopathy (HAM) a chronic, disabling inflammation of the spinal cord. | 27336911 |
| Airway structure, Inflammation | Altered Intercellular Communication | Nitric oxide (NO) is marker of inflammation, and fractional exhaled NO (FeNO) is a marker of airway inflammation. | 27337107 |
| Ichthyosis Bullosa of Siemens, Viscero-Visceral Reflex, Urinary Calculi, Irritable Bowel Syndrome | Altered Intercellular Communication | The neurotransmitter pathways in irritable bowel syndrome (IBS) and urinary stone attacks are both related to serotonin, and each disease may be influenced by viscero-visceral hyperalgesia. | 27337114 |
| Inflammation | Altered Intercellular Communication | Median ferritin concentrations (adjusted for inflammation) ranged between 48 and 91 mg/L among Cambodian women and between 54 and 55 mg/L among Congolese children. | 27337742 |
| Central Serous Chorioretinopathy | Altered Intercellular Communication | The results revealed signs of Central Serous Chorioretinopathy in both eyes which may have been due to various hormonal changes in pregnancy with resultant changes in refractive error. | 27337860 |
| Inflammation, Fibrosis Assessment, Hypoxia | Altered Intercellular Communication | Compared to IMA-PVAT, C-PVAT exhibited more pronounced angiogenesis and inflammation, as indicated by significantly higher numbers of PECAM1-positive vessels and CD68-positive macrophages, and was characterized by a greater extent of fibrosis and hypoxia. | 27337945 |
| Inflammation, Fibrosis Assessment, Hypoxia, Plaque, Atherosclerotic | Altered Intercellular Communication | A higher degree of local tissue hypoxia and up-regulation of leptin expression in the perivascular adipose tissue, along with increased vascularization, inflammation, and fibrosis, may contribute to the increased atherosclerotic plaque burden in the coronary arteries compared to the IMA. | 27337945 |
| Refractory anemias, Inflammation, Obesity | Altered Intercellular Communication | The dominance of obesity in females and the different behaviour of disease activity markers in relation to the BMI in females indicate that additional parameters need to be considered when analysing the impact of obesity on inflammation in RA. | 27338263 |
| Inflammation, Cerebral Edema | Altered Intercellular Communication | Substance P (SP), a member of tachykinin family, is involved in the inflammation of the central nervous system and in the appearance of cerebral edema. | 27338372 |
| Airway structure | Altered Intercellular Communication | PMcoarse was associated with an increase in FENO, indicating sub-clinical airway inflammation in healthy children. | 27338437 |
| Neurodegenerative Disorders, Inflammation | Altered Intercellular Communication | Emerging studies suggest that in neurodegenerative diseases, aggregation of one protein species can promote other proteinopathies and that inflammation plays an important role in this process. | 27339073 |
| Inflammation | Altered Intercellular Communication | Histopathology of the lung tissue revealed acute and chronic inflammation. | 27339583 |
| Peptide Hydrolases, Inflammation | Altered Intercellular Communication | Proteolytic damage or inflammation of the vessels may also play a significant part. | 27339635 |
| Multiple polyps, Inflammation, Superficial ulcer, Pathology, Ulcer | Altered Intercellular Communication | Ulcers, inflammation and erosions (13%), polyposis syndromes (9.8%) and vascular pathologies (7.4%) were the most common endoscopic findings. | 27339642 |
| Inflammation, Chronic Kidney Diseases | Altered Intercellular Communication | Inflammation and Progression of CKD: The CRIC Study. | 27340285 |
| Alzheimers Disease | Altered Intercellular Communication | Folic Acid Supplementation Mitigates Alzheimer's Disease by Reducing Inflammation: A Randomized Controlled Trial. | 27340344 |
| Inflammation, Data types - Address | Altered Intercellular Communication | Inflammation may play an important role in the interaction between folic acid and AD. | 27340344 |
| Inflammation, Fibrosis Assessment | Altered Intercellular Communication | Biopsies were also assessed for inflammation and fibrosis, and for the association of SM levels with liver volume, liver function tests, and lipid profiles. | 27340749 |
| Inflammation, Myeloproliferative disease, Hematologic Neoplasms | Altered Intercellular Communication | It has been shown that angiogenesis and inflammation play an important role in development of most hematological malignancies including the myeloproliferative neoplasm (MPN). | 27341002 |
| Inflammation, Intracranial Aneurysm | Altered Intercellular Communication | Aneurysmal wall enhancement (AWE) has emerged as a new possible biomarker for depicting inflammation of the intracranial aneurysm (IA). | 27341856 |
| Inflammation, Pain Distress Question | Altered Intercellular Communication | BACKGROUND Inflammation is considered as one of the main pathogeneses in OA-induced pain. | 27342658 |
| Inflammation, Refractory anemias, Autoimmune Diseases, Rheumatoid Arthritis, Erosion of bone | Altered Intercellular Communication | Rheumatoid arthritis (RA) is a systemic autoimmune disease resulting in chronic inflammation of the synovium and consequent cartilage and bone erosion. | 27342690 |
| Refractory anemias, Hyperplasia | Altered Intercellular Communication | PGK1, a glycolytic enzyme catalyzing the conversion of 3-phosphoglycerate into 2-phosphoglycerate, has increased expression in synovial tissues and blood of RA, which may be involved in pro-inflammation and synovial hyperplasia of the disease. | 27342824 |
| Inflammation | Altered Intercellular Communication | The early inflammation reaction to rhBMP-2 manifesting with radicular symptoms has been previously reported in patients undergoing transforaminal lumbar interbody fusion (TLIF). | 27343729 |
| Inflammation | Altered Intercellular Communication | Inflammation-associated lymphangiogenesis (IAL) has been identified as part of several acute and chronic inflammation. | 27344132 |
| Inflammation, Observation Method - Coagulation | Altered Intercellular Communication | Association of novel metrics of particulate matter with vascular markers of inflammation and coagulation in susceptible populations -results from a panel study. | 27344265 |
| Inflammation | Altered Intercellular Communication | Epidemiological studies have shown adverse effects of ambient air pollutants on health with inflammation and oxidative stress playing an important role. | 27344265 |
| Diabetic Nephropathy, Diabetes Mellitus, Non-Insulin-Dependent, Cardiovascular Diseases | Altered Intercellular Communication | Greater renal function decline (RFD) in type 2 diabetes (T2DM) has been suggested in men compared with women, and imbalances in estrogen/androgen levels have been associated with cardiovascular disease mortality in elderly men, but it remains unclear whether sex hormone disequilibrium is related to diabetic nephropathy (DN) in men with T2DM. | 27344412 |
| ARCN1 gene, Inflammation, AHR wt Allele, Chronic Obstructive Airway Disease, Asthma | Altered Intercellular Communication | The impact of airway hyperreactivity (AHR) on respiratory mortality and systemic inflammation among patients with chronic obstructive pulmonary disease (COPD) is largely unknown. | 27345171 |
| Inflammation, Malnutrition | Altered Intercellular Communication | The predictive value of malnutrition - inflammation score on 1-year mortality in Turkish maintenance hemodialysis patients. | 27345184 |
| Inflammation, Hemorrhage, Meckel Diverticulum, Obstruction | Altered Intercellular Communication | The most common complications of Meckel's diverticulum are inflammation, bleeding and obstruction. | 27345602 |
| Diabetes Mellitus, Non-Insulin-Dependent | Altered Intercellular Communication | Hormonal milieu has long been known to play an important role in the development of type 2 diabetes (T2D). | 27345735 |
| Fibrous, Fibrous stenosis | Altered Intercellular Communication | Inflammation-dominant stenosis (type 1) was found in 8.9% of the patients, web-associated fibrous stenosis (type 2) in 19.5%, and fibrous (type 3) in 71.6%. | 27346484 |
| Inflammation, Pseudoaneurysm | Altered Intercellular Communication | In some cases, infected pseudoaneurysms can be masked by the excessive inflammation of surrounding tissues. | 27346681 |
| Inflammation, Infection, Anemia | Altered Intercellular Communication | High RBC EPA status, inflammation and infections, and lower education levels may contribute to the prevalence of anaemia in this population, which is not related to iron status. | 27348115 |
| Inflammation | Altered Intercellular Communication | The serum TB may play a crucial role in inflammatory by contributing to inhibit the inflammation effect. | 27349017 |
| Inflammation, Kit Ligand, human, Atherosclerosis | Altered Intercellular Communication | Several lines of evidence suggest that slow coronary flow (SCF) phenomenon seems to be an early form of atherosclerosis and low-grade inflammation plays a role in the development of SCF. | 27349023 |
| Inflammation, Plaque, Atherosclerotic | Altered Intercellular Communication | The formation of monocyte-platelet aggregates and neutrophil-platelet aggregates (MPA and NPA, respectively) is influenced by inflammation, but also might contribute to an exacerbation of inflammatory responses in atherosclerotic plaque. | 27352829 |
| Mastitis, Inflammation, Edema | Altered Intercellular Communication | In cases of mastitis with abscess formation, there is a characteristic appearance, with a central very soft area (abscess cavity) and a very stiff outer rim (edema and inflammation). | 27353071 |
| Inflammation, Calcified (qualifier), Calcinosis, Diabetes Mellitus | Altered Intercellular Communication | Histopathological assessment of calcification and inflammation of calcific aortic valves from patients with and without diabetes mellitus. | 27353274 |
| Inflammation, Calcinosis | Altered Intercellular Communication | Inflammation and calcification were assessed by immunohistochemistry and immunofluorescence staining. | 27353274 |
| Inflammation, Calcinosis, diabetic | Altered Intercellular Communication | Aortic valves from diabetic patients show more calcification, while inflammation is similar in both patient populations. | 27353274 |
| Calcinosis, Congenital bilateral aplasia of vas deferens, diabetic | Altered Intercellular Communication | Considering the generally accepted theory of an inflammation-dependent mechanism of calcification, these data suggest that in patients with CAVD requiring valve replacement, diabetic patients could be molecularly in a more advanced disease stage with a higher grade of mineralization than non-diabetic patients. | 27353274 |
| helium, Inflammation | Altered Intercellular Communication | Electrolyte abnormalities and mild inflammation are involved in the pathogenesis of HE. | 27353278 |
| Inflammation, Stomach ache, Diarrhea, Dyspepsia, Digestive System Disorders, Constipation | Altered Intercellular Communication | These medicinal plant species were used commonly as an ethno medicine against 26 various digestive disorders out of which most frequently occurred are; stomach ache, diarrhea, indigestion, constipation and inflammation etc. | 27353866 |
| Inflammation, Ulcerative Colitis | Altered Intercellular Communication | Appendiceal orifice inflammation is associated with proximal extension of disease in patients with ulcerative colitis. | 27354363 |
| Inflammation, Ulcerative Colitis | Altered Intercellular Communication | Ulcerative colitis (UC) is considered to be a disease of continuous mucosal inflammation extending proximally from the rectum. | 27354363 |
| Inflammation | Altered Intercellular Communication | However, appendiceal orifice inflammation (AOI) is a skip lesion with segments of continuous involvement from the rectum. | 27354363 |
| Inflammation, Edema | Altered Intercellular Communication | The degree of AOI was graded endoscopically as follows: 0 (no inflammation); 1 (slight oedema); 2 (moderate inflammation); and 3 (marked inflammation). | 27354363 |
| Proctitis, Inflammatory disease of mucous membrane | Altered Intercellular Communication | Our results showed correlations between AOI and subsequent proximal extension of mucosal inflammation in patients with proctitis. | 27354363 |
| Inflammation | Altered Intercellular Communication | Increasing mGPS (systemic inflammation) and deteriorating PS were associated with deterioration in quality-of-life parameters (P < .001). | 27354484 |
| Inflammation, Primary malignant neoplasm | Altered Intercellular Communication | Systemic inflammation was associated with quality-of-life parameters independent of PS in patients with advanced cancer. | 27354484 |
| Inflammation, Observation Method - Coagulation, Blood Coagulation Disorders, platelet dysfunction | Altered Intercellular Communication | Trauma-associated coagulopathy is a complex process involving inflammation, coagulation, and platelet dysfunction. | 27355402 |
| Hypermetabolism, Burn Specimen Source Codes, Inflammation, Hyperglycemia | Altered Intercellular Communication | Inflammation and hypermetabolism post burn predisposes to hyperglycemia and insulin resistance. | 27355659 |
| Inflammation, Subarachnoid Hemorrhage, Cerebral Ischemia | Altered Intercellular Communication | Considering the important role of inflammation in the pathogenesis of delayed cerebral ischaemia, we investigated whether matrix metalloproteinase-9 (MMP-9) may be an efficient biomarker for predicting elayed cerebral ischaemia after subarachnoid haemorrhage. | 27355865 |
| Thrombosis | Altered Intercellular Communication | Humoral autoimmune-mediated inflammation plays a role in atherogenesis, and potentially in arterial thrombosis. | 27356567 |
| Inflammation | Altered Intercellular Communication | Bacteria of leg atheromatous arteries responsible for inflammation. | 27356591 |
| Ischemia, Inflammation, Necrosis | Altered Intercellular Communication | Ischaemia of the lower limbs is frequently followed by inflammation and, in advanced cases, necrosis of peripheral tissues. | 27356591 |
| Inflammation, Ischemic | Altered Intercellular Communication | They may predispose to inflammation secondary to ischaemic changes. | 27356591 |
| Inflammation, Hepatitis, Alcoholic | Altered Intercellular Communication | The damage-associated molecular pattern HMGB1 is elevated in human alcoholic hepatitis, but does not seem to be a primary driver of inflammation. | 27357188 |
| Inflammation, Moist, Hepatitis, Alcoholic | Altered Intercellular Communication | The role of sterile inflammation caused by release of damage-associated molecular patterns (DAMP) remains unclear in human alcoholic hepatitis (AH). | 27357188 |
| Tissue damage, Inflammation, Moist | Altered Intercellular Communication | The DAMP, high mobility group box-1 protein (HMGB1) is released by tissue damage and inflammation. | 27357188 |
| Inflammation | Altered Intercellular Communication | This combined with an increased TLR4 expression, but an unaffected cytokine response to HMGB1 suggest that HMGB1 is not the primary driver of inflammation in AH. | 27357188 |
| Inflammation, "Alzheimers Disease", Data types - Address | Altered Intercellular Communication | Inflammation is becoming increasingly recognized as an important contributor to Alzheimer's disease (AD) pathogenesis. | 27357286 |
| APP gene, Inflammation | Altered Intercellular Communication | AAA is caused by segmental weakening of the aortic walls and progressive aortic dilation leading to the eventual rupture of the aorta, accompanied by intense inflammation. | 27358138 |
| IgG4-Related Sclerosing Disease | Altered Intercellular Communication | IgG4-related disease (IgG4-RD) is a chronic, systemic, inflammatory condition of unknown aetiology. | 27358392 |
| Inflammation | Altered Intercellular Communication | Metabolic inflammation contributes to the development of insulin resistance (IR), but the roles of different inflammatory and other cytokines in this process remain unclear. | 27362289 |
| Pain Distress Question, Conjunctivitis | Altered Intercellular Communication | Pain was significantly relieved, conjunctival inflammation was markedly resolved, and the central descemetocele area became thicker with scar formation in all patients. | 27362878 |
| Scleritis, Orbital Pseudotumor, Exacerbation of cGVHD | Altered Intercellular Communication | Two of 11 (18%) patients on rituximab had flares of scleritis and orbital inflammation but not PUK. | 27362884 |
| Inflammation, Fibrosis Assessment, Intrahepatic bile duct | Altered Intercellular Communication | Compared with the malignant group, patients in the benign group were more likely to show severe periportal inflammation in noninvolved liver (P < 0.001), fibrosis around intrahepatic bile duct (P < 0.001), and more IgG4-positive plasma cells (P < 0.001) on liver pathology. | 27363632 |
| Inflammation, Electrocardiogram: myocardial infarction (finding) | Altered Intercellular Communication | Immune cell-mediated inflammation is an essential process for mounting a repair response after myocardial infarction (MI). | 27364164 |
| Inflammation, Fibrosis Assessment, Hyperplastic Polyp, muscle hyperplasia, Hypertrophy | Altered Intercellular Communication | For each layer of bowel wall (mucosa including muscularis mucosae [MU], submucosa [SM], muscularis propria [MP], subserosal adventitia [SS]), histological abnormalities were evaluated individually, including active and chronic inflammation, fibrosis, smooth muscle hyperplasia or hypertrophy, neuronal hypertrophy and adipocyte proliferation. | 27364949 |
| Inflammation, Subject Disease Milestones Domain, Hyperplastic Polyp, muscle hyperplasia, Hypertrophy | Altered Intercellular Communication | The most significant histopathological features characterizing the stricturing intestines were smooth muscle hyperplasia of SM, hypertrophy of MP and chronic inflammation. | 27364949 |
| Fibrosis Assessment, Hypertrophy and Hyperplasia, Chronic inflammation, Fibromuscular Dysplasia | Altered Intercellular Communication | The overall muscular hyperplasia/hypertrophy was positively correlated with chronic inflammation and negatively correlated with fibrosis, whereas SM muscular hyperplasia was also associated with MU active inflammation. | 27364949 |
| Crohn Disease, muscle hyperplasia | Altered Intercellular Communication | The 'inflammation-smooth muscle hyperplasia axis' may be the most important in the pathogenesis of Crohn's strictures. | 27364949 |
| Inflammation, Metabolic Diseases | Altered Intercellular Communication | This association is partially mediated by metabolic disorders and inflammation. | 27365403 |
| Hepatitis, Obesity | Altered Intercellular Communication | The role of NK cells in visceral adipose tissue (VAT) and liver inflammation in obesity is not fully understood. | 27365528 |
| Inflammation, physiopathological, ETV3 wt Allele, Metabolic Syndrome X | Altered Intercellular Communication | One of the pathophysiologies in the development of DES is inflammation, and metabolic syndrome (MetS), which is highly prevalent in the general population, is a well-known chronic and systemic inflammatory condition. | 27366012 |
| Inflammation, physiopathological, ETV3 wt Allele, Metabolic Syndrome X | Altered Intercellular Communication | One of the pathophysiologies in the development of DES is inflammation, and metabolic syndrome (MetS), which is highly prevalent in the general population, is a well-known chronic and systemic inflammatory condition. | 27366012 |
| Inflammation, Dryness of eye, PEELING SKIN SYNDROME | Altered Intercellular Communication | HCQ at 300 mg daily for 12 weeks has no apparent clinical benefit for dry eye and systemic inflammation in pSS (ClinicalTrials.gov. | 27366013 |
| Inflammation, Primary malignant neoplasm, Hypersensitivity | Altered Intercellular Communication | Despite its important role in allergies and inflammation, little is known about how extracellular TCTP affects cancer progression. | 27367023 |
| Inflammation, Loneliness, Depression, CTCAE, Atherosclerosis | Altered Intercellular Communication | Loneliness, Depression, and Inflammation: Evidence from the Multi-Ethnic Study of Atherosclerosis. | 27367428 |
| Degenerative polyarthritis, Inflammation | Altered Intercellular Communication | Since Sirt1 activity is known to be affected by several stresses, including inflammation and oxidative stress, as well as aging, SIRT may be involved in the development of OA. | 27367673 |
| Inflammation, Acute otitis media | Altered Intercellular Communication | Conventional treatment for acute otitis media mainly targets bacteria with antibiotics, neglecting to control for mediators of inflammation. | 27368439 |
| Inflammation, Acute otitis media, Otitis Media with Effusion, Infectious Otitis Media | Altered Intercellular Communication | Mediators of inflammation, such as leukotrienes, have been identified in patients with acute otitis media (AOM) or subsequent secretory otitis media (SOM). | 27368439 |
| Inflammation, Infectious Otitis Media | Altered Intercellular Communication | The results indicate that combined treatment of AOM with antibiotics and a leukotriene antagonist to control inflammation is useful for preventing progression to persistent SOM. | 27368439 |
| Pelvic Inflammatory Disease | Altered Intercellular Communication | We presume that-in the present case-the expansive capacity of the uterine wall may have been reduced after the series of severe pelvic inflammations. | 27370269 |
| Inflammation | Altered Intercellular Communication | Inflammation induced by the activation of cytokines and neuropeptides is implied in its pathophysiology. | 27371188 |
| Inflammation, Migraine Disorders, Atherosclerosis | Altered Intercellular Communication | There is an association between inflammation and atherosclerosis in patients with migraine. | 27371188 |
| Migraine Disorders, Inflammation, Atherosclerosis | Altered Intercellular Communication | In children with migraine, an evaluation of CIMT can be used as a non-invasive imaging modality to detect atherosclerosis, which develops in the context of chronic inflammation. | 27371188 |
| Hyperglycemia, Inflammation, Impaired cognition | Altered Intercellular Communication | Hyperglycemia, inflammation, and oxidative stress are thought to be involved in the pathogenesis of cognitive decline. | 27371673 |
| Inflammation | Altered Intercellular Communication | The mechanisms might be partly explained by the effect of DPP4 on inflammation and oxidative stress. | 27371673 |
| Inflammation, Vasculitis, CTCAE | Altered Intercellular Communication | It is a systemic vasculitis characterized by diffuse inflammation of medium and small blood vessels. | 27371760 |
| Inflammation | Altered Intercellular Communication | There was no association between inflammation and rate of hip BMD loss. | 27371811 |
| Inflammation, Fracture | Altered Intercellular Communication | We conclude that inflammation may play an important role in the etiology of fractures in older men. | 27371811 |
| Inflammation, Fibrosis Assessment, Traumatic injury | Altered Intercellular Communication | Delayed changes include a tissue response consisting of inflammation, fibrosis and neo-osteogenesis induced by trauma and an immunologic reaction to a foreign body. | 27371868 |
| Inflammation, Kidney Failure, Acute, Endothelial dysfunction | Altered Intercellular Communication | All biomarkers of inflammation and endothelial dysfunction were associated with AKI. | 27372077 |
| Inflammation, Kidney Failure, Acute, Critical Illness | Altered Intercellular Communication | In critically ill patients, plasma concentration of the endothelial growth factors Ang-1 and Ang-2 are associated with AKI, independently of inflammation. | 27372077 |
| Inflammation, Arthritis, Psoriatic | Altered Intercellular Communication | Active peripheral inflammation is associated with pro-atherogenic lipid profile in psoriatic arthritis. | 27373499 |
| Arthritis | Altered Intercellular Communication | Our findings suggest an association between peripheral joint inflammation and lipid dysregulation in PsA. | 27373499 |
| Glaucoma, CTCAE, Optic Neuritis | Altered Intercellular Communication | Optic neuritis (ON) is unilateral painful optic nerve inflammation in a young healthy female diagnosed by excluding glaucoma. | 27373939 |
| Inflammation, Malnutrition | Altered Intercellular Communication | It reduces burden of inflammation and malnutrition and this effect may cause beneficial effect on HR-QoL. | 27374393 |
| Neuromyelitis Optica, N-nitrosomorpholine | Altered Intercellular Communication | Neuromyelitis optica (NMO) is a rare neuro-inflammatory condition characterized by acute relapses causing severe visual or physical disability. | 27374494 |
| Inflammation, Communicable Diseases, Diabetic Foot, Ulcer, Empyema, Pleural | Altered Intercellular Communication | NPWT has a fixed role in the treatment of stage IV pressure ulcers at sacrum or ischium, pyothorax, infection and inflammation because of internal joint prosthesis or an internal fixation device and diabetic foot syndrome. | 27374835 |
| Infection | Altered Intercellular Communication | Every fourth to fifth case hospitalised for disruption of surgical wounds or infections following a procedure (24*1%), as well as for infections and inflammations because of internal joint prosthesis or because of an internal fixation device was treated with NPWT (22*9%). | 27374835 |
| Adrenal mass, Malignant Neoplasms | Altered Intercellular Communication | Discovery of an adrenal mass needs further evaluation in order to exclude malignancy and hormonal secretion. | 27376430 |
| Inflammation, Pituitary Gland | Altered Intercellular Communication | Significant pituitary mass reduction with regression of the inflammation to the cavernous sinuses was documented. | 27376431 |
| Inflammation | Altered Intercellular Communication | Faecolith is an extremely rare cause of acute inflammation of the caecum presenting as a mass which is usually treated by limited right hemicolectomy. | 27377227 |
| Inflammation, Neoplasms | Altered Intercellular Communication | This suggests an environmental field effect that promotes multiple tumours likely in the background of inflammation. | 27377421 |
| Inflammation | Altered Intercellular Communication | We may say that the improvement of the above parameters could reduce inflammation and oxidative stress and vascular damages what would extend life expectancy and quality of life of this group of patients. | 27377683 |
| Airway structure, Pseudomonas aeruginosa, Colonization | Altered Intercellular Communication | Colonization of CF patients' upper airways with S. aureus contributes more decisively to upper airway inflammation than P. aeruginosa. | 27377929 |
| Benign prostatic hypertrophy, prostatitis | Altered Intercellular Communication | Chronic Prostate Inflammation is Associated with Severity and Progression of Benign Prostatic Hyperplasia, Lower Urinary Tract Symptoms and Risk of Acute Urinary Retention. | 27378134 |
| Inflammation, Prostate carcinoma, Benign prostatic hypertrophy | Altered Intercellular Communication | The association of acute and chronic inflammation detected on baseline biopsies and benign prostatic hyperplasia related parameters, including I-PSS (International Prostate Symptom Score) and prostate volume, at multiple time points during 4 years in men randomized to placebo enrolled in the REDUCE prostate cancer prevention study was analyzed with the Student t-test. | 27378134 |
| Inflammation, Benign prostatic hypertrophy | Altered Intercellular Communication | The association of inflammation with newly developed benign prostatic hyperplasia/lower urinary tract symptoms and benign prostatic hyperplasia progression in patients with existing benign prostatic hyperplasia/lower urinary tract symptoms was analyzed with univariable and multivariable Cox models. | 27378134 |
| Inflammation | Altered Intercellular Communication | Acute and chronic inflammation was seen in baseline negative biopsies of 641 (15.6%) and 3,216 (78.3%) of the 4,109 men in the study. | 27378134 |
| Inflammation, Benign prostatic hypertrophy | Altered Intercellular Communication | The presence of acute and chronic inflammation was not associated with the incidence of benign prostatic hyperplasia/lower urinary tract symptoms in men without those conditions at baseline or the progression of symptomatic benign prostatic hyperplasia in men with benign prostatic hyperplasia/lower urinary tract symptoms at baseline. | 27378134 |
| Inflammation | Altered Intercellular Communication | Chronic inflammation at baseline was associated with an increased risk of acute urinary retention (HR 1.6-1.8, p = 0.001). | 27378134 |
| Inflammation, Benign prostatic hypertrophy | Altered Intercellular Communication | Our longitudinal evaluation of REDUCE patients randomized to placebo for 4 years confirmed that chronic inflammation is associated with severity and the progression of benign prostatic hyperplasia and benign prostatic hyperplasia/lower urinary tract symptom outcomes. | 27378134 |
| Inflammation, Atherosclerosis | Altered Intercellular Communication | Increasing evidence suggests that inflammation and increased macrophage activity have a central role in pathogenesis of atherosclerosis. | 27378685 |
| Amyotrophic Lateral Sclerosis, Inflammation | Altered Intercellular Communication | Altogether, our data indicate that IP3R2 protects against the negative effects of inflammation, suggesting that the increase in IP3R2 expression in ALS patients is a protective response. | 27378687 |
| Inflammation, Rheumatic Fever, Coronary Artery Disease | Altered Intercellular Communication | Plasma vitamin D levels and inflammation in the aortic wall of patients with coronary artery disease with and without inflammatory rheumatic disease. | 27379927 |
| Inflammation, Interferon-Related DNA Damage Resistance Gene Signature, Coronary Artery Disease, Inflammatory disorder | Altered Intercellular Communication | Vitamin D modulates inflammation, and this may explain the observed associations between vitamin D status and disorders driven by systemic inflammation, such as coronary artery disease (CAD) and inflammatory rheumatic diseases (IRDs). | 27379927 |
| Inflammation, Malignant neoplasm of larynx | Altered Intercellular Communication | Besides tobacco and alcohol, diet and inflammation have been suggested to be important risk factors for laryngeal cancer. | 27379989 |
| Inflammation, Malignant neoplasm of larynx | Altered Intercellular Communication | In this study, we examined the role of diet-associated inflammation, as estimated by dietary inflammatory index (DII) scores, in laryngeal cancer in a multicentre case-control study conducted between 1992 and 2000 in Italy. | 27379989 |
| Intraocular inflammation | Altered Intercellular Communication | Main outcome measures were changes in visual acuity, intraocular inflammation, concomitant immunosuppressive drug or intravitreal steroid, and adverse events. | 27380253 |
| Intraocular inflammation | Altered Intercellular Communication | Intraocular inflammation was controlled in 10 of 14 patients (71%) at 1 year, with a mean dose of 6.2 mg/day prednisone. | 27380253 |
| Viremia | Altered Intercellular Communication | Cytomegalovirus viremia was detected in 16 (72.7%) of the 22 patients with inflammation-associated complications. | 27380428 |
| Inflammation, Heart failure | Altered Intercellular Communication | Heart failure is associated with low-grade inflammation. | 27380510 |
| Inflammation, Heart failure | Altered Intercellular Communication | In the present study we sought to assess the prognostic impact of orosomucoid, a marker of inflammation, in outpatients with heart failure. | 27380510 |
| Low Back Pain, Inflammation | Altered Intercellular Communication | Inflammation in low back pain may be detected from the peripheral blood: suggestions for biomarker. | 27380953 |
| Inflammation, Neurogenic Inflammation, Pain Distress Question | Altered Intercellular Communication | In the present study, we examined evidence of inflammation in the peripheral blood and demonstrated significant changes in neuroinflammation markers in subjects with chronic low back pain in comparison with control subjects. | 27380953 |
| Intraocular inflammation, Primary intraocular non-Hodgkin malignant lymphoma, Uveitis | Altered Intercellular Communication | To present challenging cases of vitreoretinal lymphoma (VRL) that was misdiagnosed as uveitis because of the apparent intraocular inflammation. | 27380976 |
| Idiopathic Inflammatory Myopathies | Altered Intercellular Communication | VRLs are severe diseases with a poor prognosis that may be misdiagnosed as idiopathic inflammatory conditions of the eye. | 27380976 |
| Tears body substance, Pain Distress Question, Inflammation, Calcific tendinitis | Altered Intercellular Communication | The lifetime prevalence of shoulder pain approaches 70%, which is mostly attributable to rotator cuff lesions such as inflammation, calcific tendinitis and tears. | 27381057 |
| Tears body substance, Inflammation, Calcific tendinitis | Altered Intercellular Communication | The collected cases included 43 cases of inflammation, 30 cases of calcific tendinitis and 26 tears. | 27381057 |
| Tears body substance, Inflammation, Calcific tendinitis | Altered Intercellular Communication | The individual accuracy of this CAD system was 88.4% for inflammation, 83.3% for calcific tendinitis and 92.3% for tears. | 27381057 |
| Inflammation, Toxicity Tests, Acute | Altered Intercellular Communication | Thus, a proportion of acute urinary toxicity in men with an intact prostate may be attributable to inflammation of the prostatic gland or urethra. | 27381895 |
| Inflammation, Middle-aged men, Fatigue | Altered Intercellular Communication | Relationship of Objectively-Measured Habitual Physical Activity to Chronic Inflammation and Fatigue in Middle-Aged and Older Adults. | 27382039 |
| Inflammation, Fatigue | Altered Intercellular Communication | Habitual (non-exercise) physical activity (PA) declines with age, and aging-related increases in inflammation and fatigue may be important contributors to variability in PA. | 27382039 |
| Inflammation, Weight decreased, Fatigue | Altered Intercellular Communication | At the 18-month follow-up, inflammation was lower in both weight loss groups, fatigue was reduced in all three groups with larger decreases in the combined group, and mean levels of habitual PA were not changed in any group. | 27382039 |
| Inflammation, Fatigue | Altered Intercellular Communication | Levels of habitual PA are lower in middle-aged and older adults with higher levels of chronic inflammation and greater self-reported fatigue. | 27382039 |
| Inflammation, Fatigue | Altered Intercellular Communication | In addition, participants who experienced greater declines in inflammation during the interventions had greater declines in fatigue and larger increases in PA. | 27382039 |
| Inflammation | Altered Intercellular Communication | Together, these results establish that vagus nerve stimulation targeting the inflammatory reflex modulates TNF production and reduces inflammation in humans. | 27382171 |
| Arthritis | Altered Intercellular Communication | One well-characterized cytokine-inhibiting mechanism, termed the "inflammatory reflex," is dependent upon vagus nerve signals that inhibit cytokine production and attenuate experimental arthritis severity in mice and rats. | 27382171 |
| Inflammation | Altered Intercellular Communication | Vaspin is a novel adipocytokine associated with glucose tolerance and chronic inflammation. | 27383120 |
| Inflammation, Malignant Neoplasms | Altered Intercellular Communication | After treatment, the sinonasal skull base is predisposed to prolonged inflammation that may render this time-point inappropriate for initial posttreatment imaging surveillance for sinonasal malignancies. | 27383662 |
| Granulomatous inflammation | Altered Intercellular Communication | To determine the proportional distribution of endobronchial tuberculosis (EBTB) subtypes and to evaluate the types of bronchoscopic diagnostic procedures that can prove granulomatous inflammation. | 27383932 |
| Granulomatous inflammation | Altered Intercellular Communication | Among the 18 patients with EBTB, granulomatous inflammation was proven by the following bronchoscopic diagnostic procedures: bronchial mucosal biopsy, in 8 (44.4%); bronchial brushing, in 7 (38.8%); fine-needle aspiration biopsy, in 2 (11.1%); and BAL, in 2 (11.1%). | 27383932 |
| Inflammation, hafnium, Depression, CTCAE | Altered Intercellular Communication | In addition, it examined whether there was a mediating relationship between social support and marital status and whether depression and inflammation influenced one another to predict mortality of HF patients. | 27384414 |
| Inflammation | Altered Intercellular Communication | Monitoring chronic HF patients who are unmarried, with elevated inflammation, or in higher NYHA class may help identify those at greater mortality risk to implement targeted intervention. | 27384414 |
| Inflammation, Gastric Cardia Carcinoma | Altered Intercellular Communication | These findings provide pathological evidence that H. pylori infectionis a driving force of gastric cardia carcinogenesis by upregulating CDX2 and inducing inflammation. | 27384681 |
| Autoimmune Diseases, Inflammation | Altered Intercellular Communication | Thrombin generation assay: interactions between chronic inflammation and haemostasis in patients with autoimmune diseases. | 27385196 |
| Inflammation, Anemia | Altered Intercellular Communication | Fixed dose of long-acting erythropoietic stimulating agents at higher frequency improves appetite, reduces inflammation and corrects anaemia in patients on haemodialysis. | 27385380 |
| Inflammation, Anemia | Altered Intercellular Communication | We demonstrate that a fixed monthly dose of CERA at a twice monthly dosing schedule improves nutrition, reduces the inflammation and corrects anaemia in patients on haemodialysis. | 27385380 |
| vascular inflammations, Endothelial dysfunction | Altered Intercellular Communication | However, involvement of vascular inflammation in endothelial dysfunction is not fully investigated in humans because of the lack of diagnostic modality to noninvasively evaluate vascular inflammation. | 27386941 |
| Inflammation, Neuropathy | Altered Intercellular Communication | Neuropathy per se may lead to skin inflammation. | 27387067 |
| Inflammation, Orbital Fractures | Altered Intercellular Communication | Delayed onset porous polyethylene implant-related inflammation after orbital blowout fracture repair: four case reports. | 27387333 |
| Inflammation | Altered Intercellular Communication | Delayed inflammation related to porous polyethylene sheet implants is very rare and no case series of this condition have been reported. | 27387333 |
| Inflammatory | Altered Intercellular Communication | Chronic and subacute orbital inflammatory signs were noted in two patients and acute fulminant orbital inflammation was found in two patients. | 27387333 |
| Inflammation | Altered Intercellular Communication | Low-grade or fulminant inflammation could complicate blowout fracture repair related with the implant. | 27387333 |
| Inflammation, Pain Distress Question | Altered Intercellular Communication | Aseptic loosening (AL) of hip prosthesis presents inflammation and pain as sign and symptom similarly to arthritis pathologies. | 27387445 |
| Degenerative polyarthritis, Inflammation | Altered Intercellular Communication | In OA, inflammation is mostly confined to the vicinity of synovial membrane while in AL macrophages infiltrated throughout the tissue. | 27387445 |
| Inflammation, Pathology | Altered Intercellular Communication | Nevertheless, in both pathologies, TGF-b1 expression was prominent in sites where the inflammation is occurring. | 27387445 |
| Diabetic Nephropathy, Inflammation | Altered Intercellular Communication | Serum and Plasma Levels of Vascular Endothelial Growth Factors in Relation to Quality of Glucose Control, Biomarkers of Inflammation, and Diabetic Nephropathy. | 27388431 |
| Inflammation, Endothelial dysfunction | Altered Intercellular Communication | Levels of vascular endothelial growth factors (VEGF) are regulated in a complex network of adipokines, glucose control, and low grade inflammation together with activated platelets, leucocytes, and endothelial dysfunction. | 27388431 |
| Diabetic Nephropathy, Inflammation, Diabetes Mellitus | Altered Intercellular Communication | Little is known about the interaction of systemic VEGF levels with quality of diabetes control, biomarkers of inflammation, and diabetic nephropathy. | 27388431 |
| Diabetic Nephropathy, Inflammation | Altered Intercellular Communication | Correlation analysis revealed a significant relationship between VEGF-A, HbA1c, inflammation, and diabetic nephropathy. | 27388431 |
| Diabetic Nephropathy, Inflammation | Altered Intercellular Communication | Mechanistic studies are needed to explore links to inflammation and diabetic nephropathy. | 27388431 |
| nervous system disorder, Inflammation | Altered Intercellular Communication | This indicates that recurrent episodes of inflammation in the CNS, as well as age, contribute to progressive neurological disease. | 27388634 |
| Inflammation | Altered Intercellular Communication | In contrast, dual (18)F-NaF bone PET/CT with early-phase scan demonstrated focal active inflammation at the surgical site of T11 spine. | 27388912 |
| Dermatitis | Altered Intercellular Communication | We showed that as a consequence, AP1S3-deficient cells up-regulate IL-1 signaling and overexpress IL-36a, a cytokine that is emerging as an important mediator of skin inflammation. | 27388993 |
| Inflammation, Rheumatism | Altered Intercellular Communication | Power Doppler ultrasonography (PDUS) is a useful method for detection of inflammation and vascularity in rheumatic diseases. | 27390300 |
| Inflammation, Fasciitis, Demographics Domain | Altered Intercellular Communication | In the remaining 3 patients with DM, significant fasciitis was not evident histologically, but mild proliferation of capillaries and mild inflammation were notable in the area of the fascia. | 27390300 |
| Inflammation | Altered Intercellular Communication | Persistent activation of NF-kB signaling is closely related to chronic inflammation and tumorigenesis. | 27391066 |
| Inflammation, Fibrosis Assessment | Altered Intercellular Communication | The lesion was totally resected, and final findings of a histopathologic examination revealed extensive fibrosis with subsiding inflammation within the tympanic membrane. | 27391508 |
| Nerve palsy, Compression, Brachial Plexus Neuritis, Optic Neuritis | Altered Intercellular Communication | Different hypotheses have been proposed for the pathophysiology of anterior interosseous nerve palsy: compression, fascicular constriction, or nerve inflammation (Parsonage-Turner syndrome). | 27391838 |
| Inflammation, Malignant Neoplasms | Altered Intercellular Communication | Histopathology from all prostate chips was assessed for inflammation and malignancy. | 27391962 |
| Inflammation, Acute myocardial ischemia | Altered Intercellular Communication | Increasing evidence suggests that inflammation and apoptosis are involved in the development of acute myocardial ischemia (AMI). | 27393910 |
| Inflammation, Atrophy of pancreas, Neoplasms | Altered Intercellular Communication | The association of serum pancreatic enzymes with pathological pancreatic atrophy and inflammation in areas adjacent to or distant from the tumor was also evaluated. | 27394653 |
| Inflammation, Neoplasms | Altered Intercellular Communication | Furthermore, low serum pancreatic amylase and lipase levels were associated with higher grade inflammation in areas distant from the tumor (P < 0.0001 and P = 0.001, respectively). | 27394653 |
| Inflammation | Altered Intercellular Communication | Nutrient patterns and chronic inflammation in a cohort of community dwelling middle-aged men. | 27395328 |
| Inflammation, Sleep Apnea, Obstructive | Altered Intercellular Communication | While an animal-sourced pattern may enhance inflammation level, a plant-sourced pattern may reduce inflammation particularly in people with less healthy lifestyles and severe obstructive apnoea. | 27395328 |
| Infarction, Inflammation, Fibrosis Assessment | Altered Intercellular Communication | Compared with PBS, vasostatin-2 treatment prevented ischemic HF in MI rats, accompanied with reduction of infarct size, remodeling, fibrosis and inflammation, mainly through inhibition of Rho, Wnt and TLR-4 pathways and modulation of renin-angiotensin system. | 27395818 |
| Bone Diseases, Inflammation, HD Term Type, Endothelial dysfunction | Altered Intercellular Communication | Inflammation, endothelial dysfunction, and mineral bone disease are critical factors contributing to morbidity and mortality in hemodialysis (HD) patients. | 27399127 |
| HD Term Type, Inflammation | Altered Intercellular Communication | Intradialytic aerobic cycling exercise programs can effectively alleviate inflammation and improve nutrition, bone mineral density, and exercise tolerance in HD patients. | 27399127 |
| Sjogrens Syndrome", Parotitis, Inflammation | Altered Intercellular Communication | A 65-year-old female patient with recurrent parotitis due to Sjogren syndrome was referred to us, complaining of weekly bouts of inflammation. | 27400144 |
| Degenerative polyarthritis, Inflammation | Altered Intercellular Communication | Our findings demonstrated that HA+PRP effectively diminished IFP adipocyte-promoted inflammation in articular chondrocytes, indicating that the IFP could be a potential therapeutic target for OA therapy. | 27400716 |
| Alzheimers Disease", Data types - Address | Altered Intercellular Communication | A neuro-inflammatory response is evident in Alzheimer's disease (AD), yet the precise mechanisms by which neuro-inflammation influences the progression of Alzheimer's disease (AD) remain poorly understood. | 27400725 |
| Myositis | Altered Intercellular Communication | The correlation between the SR and the pathologic grading suggests that SSE could be an important tool in not only the diagnosis of but also in measuring the degree of muscular inflammation. | 27401595 |
| Inflammation, Liver carcinoma, FAM126A gene | Altered Intercellular Communication | The systemic inflammation biomarker, Neutrophil-to-Lymphocyte Ratio (NLR), has been reported as one of the adverse prognostic factors for hepatocellular carcinoma (HCC) patient. | 27401641 |
| Inflammation, Pelvic Pain | Altered Intercellular Communication | Adverse events, such as pelvic pain, inflammation, or de novo urgency, were not observed in any case during follow-up. | 27401646 |
| Disease | Altered Intercellular Communication | We postulate that acupuncture may reduce inflammation/swelling of the synovial membrane of the tendon sheath, which predominates when the disorder is of short duration. | 27401746 |
| Inflammatory Bowel Diseases, Inflammation | Altered Intercellular Communication | Faecal calprotectin, an established biomarker used to assess mucosal inflammation, has been shown to correlate with endoscopic activity in inflammatory bowel disease (IBD). | 27402063 |
| Pain Distress Question, Inflammation | Altered Intercellular Communication | The cause of pain in the course of calcaneal spur is inflammation of the attachment of the plantar fascia, which plays an important role in the process of walking and is seriously strained during different types of movement. | 27402210 |
| Inflammation, Primary malignant neoplasm, Lithiasis | Altered Intercellular Communication | Although ADMG is benign in nature, lithiasis, and chronic inflammation secondary to it may lead to dysplastic changes and cancer. | 27403774 |
| Inflammation, Fibrosis Assessment, Non-alcoholic Fatty Liver Disease, Fatty degeneration | Altered Intercellular Communication | Clinical characteristics, biochemical profile, and histopathological data [steatosis, NAFLD activity score (NAS), hepatocyte ballooning, lobular inflammation, and degree of fibrosis] were obtained at each time point. | 27405478 |
| Inflammation | Altered Intercellular Communication | The changes in lobular inflammation and hepatocyte ballooning were not statistically significant on follow-up. | 27405478 |
| Inflammation | Altered Intercellular Communication | Considering patient preferences, drugs with daily or less frequent dosing that protect against bowel inflammation from gluten cross contamination would be best accepted. | 27405659 |
| Inflammation | Altered Intercellular Communication | It involves multiple mechanisms such as physiological risk factors, chronic inflammation, oxidant-antioxidant imbalance and proteolytic attack on extracellular matrix by matrix metalloproteinases (MMP). | 27405842 |
| Malignant tumor of colon, Inflammation, Adenoma, Ulcerative Colitis | Altered Intercellular Communication | The crude incidence rate of developing colon cancer in patients with UC was 2.45 (95 % CI 1.06-4.83) per 1000 PYD and in those with UC and polypoid adenomas within the extent of inflammation was 11.07 (95 % CI 3.59-25.83) per 1000 PYD. | 27405991 |
| Inflammation, Colorectal Carcinoma, Ulcerative Colitis | Altered Intercellular Communication | Adjusted hazards ratio of developing CRC on follow-up in UC patients with polypoid dysplastic adenomatous lesions within the extent of inflammation was 4.0 (95 % CI 1.3-12.4). | 27405991 |
| Inflammation, Colorectal Carcinoma, Ulcerative Colitis, Adenomatous Polyps | Altered Intercellular Communication | The risk of developing CRC is significantly higher in UC patients with polypoid adenomatous lesions, within the extent of inflammation, despite endoscopic resection. | 27405991 |
| ARCN1 gene, Inflammation | Altered Intercellular Communication | Perturbation experiments with a miR-218-5p mimic or inhibitor demonstrated a protective role of miR-218-5p in cigarette smoke-induced inflammation and COPD. | 27409149 |
| Renal Cell Carcinoma | Altered Intercellular Communication | Systemic immune-inflammation index predicts the clinical outcome in patients with metastatic renal cell cancer treated with sunitinib. | 27409344 |
| Refractory Cytopenia of Childhood, Renal Cell Carcinoma | Altered Intercellular Communication | In this retrospective analysis, we explored the prognostic and predictive value of the systemic immune-inflammation index (SII), based on lymphocyte, neutrophil, and platelet counts, at baseline and changes at week 6 during first-line sunitinib in patients with metastatic renal cell cancer (RCC). | 27409344 |
| Inflammation, Malnutrition | Altered Intercellular Communication | In conclusion, long-term moderate CR without malnutrition induces a significant and persistent inhibition of inflammation without impairing key in vivo indicators of cell-mediated immunity. | 27410480 |
| Inflammation, Overweight | Altered Intercellular Communication | Insulin resistance was increased in metabolically healthy overweight or obese participants (median HOMA-IR 2.63, 95% CI: 1.79-3.65, P<0.001) relative to normal-weight participants (median HOMA-IR 1.67, 95% CI: 1.08-2.67, P<0.001) as was sub-clinical inflammation but metabolically healthy overweight or obese individuals were not at increased risk of cardiovascular mortality compared with the metabolically healthy normal-weight individuals (hazard ratio 1.13, 95% CI: 0.34-3.72, P=0.8). | 27412654 |
| Sepsis, Inflammation, Acute inflammation | Altered Intercellular Communication | Consecutive ICU patients were allocated to: sepsis (n = 15), postoperative inflammation (n = 23) and intoxication without inflammation (n = 7) groups. | 27414210 |
| Chronic Kidney Diseases | Altered Intercellular Communication | Inflammation, vitamin D and dendritic cell precursors in chronic kidney disease. | 27414487 |
| Inflammation, Chronic Kidney Diseases, Diabetes Mellitus | Altered Intercellular Communication | Instead, inflammation as a common phenomenon in CKD and diabetes mellitus had the main influence on the decrease in DCP. | 27414487 |
| Diabetic Nephropathy, Inflammation, Diabetes Mellitus, Non-Insulin-Dependent | Altered Intercellular Communication | Inflammation plays a role in the development of diabetic nephropathy (DN) in type 2 diabetes. | 27416772 |
| Inflammation, Cirrhotic, Dysbiosis | Altered Intercellular Communication | HCV eradication does not impact gut dysbiosis or systemic inflammation in cirrhotic patients. | 27417456 |
| Inflammation, Liver Cirrhosis, Dysbiosis | Altered Intercellular Communication | To define the impact of sustained virological response (SVR) on gut dysbiosis and systemic inflammation in HCV cirrhosis patients. | 27417456 |
| Inflammation | Altered Intercellular Communication | Significant epithelial inflammation was present in 130 (16%) Cytosponge samples, 32 of which had ulcer slough. | 27417524 |
| Herpes Esophagitis, Inflammation, Esophagitis, Candida (fungus) | Altered Intercellular Communication | Candida and significant inflammation was detected in a further 22 (2.3%) cases; epithelial infiltration with >15 eosinophils/high-power field reflecting possible eosinophilic oesophagitis (EOE) in five (0.6%); and viral inclusions suggestive of herpes oesophagitis in one (0.1%). | 27417524 |
| Inflammation, Candida (fungus), Viral esophagitis | Altered Intercellular Communication | Eighteen cases with severe inflammation, six with candida and two with EOE were detected only at endoscopy, while 18 with candida and significant inflammation, 13 with ulcer slough, one probable EOE and one viral oesophagitis were identified on the Cytosponge only. | 27417524 |
| Malaria, Falciparum, Inflammation, Bacteremia | Altered Intercellular Communication | Reduced Parasite Burden in Children with Falciparum Malaria and Bacteremia Coinfections: Role of Mediators of Inflammation. | 27418744 |
| Psoriatic Juvenile Idiopathic Arthritis, Inflammatory abnormality of the eye, Psoriasis, Uveitis | Altered Intercellular Communication | Psoriasis and Psoriatic Arthritis-Related Uveitis: Different Ophthalmological Manifestations and Ocular Inflammation Features. | 27419848 |
| Inflammation, Diabetic Retinopathy | Altered Intercellular Communication | Because inflammation contributes to diabetic retinopathy, it is plausible that neutrophil extracellular trap formation actively occurs in diabetic retinopathy. | 27420129 |
| Inflammation, Cardiovascular Diseases, Atherosclerosis, Cyclophosphamide/Vincristine/Dacarbazine Regimen, Cessation of life | Altered Intercellular Communication | Introduction Cardiovascular disease (CVD) is the leading cause of death in post menopausal women, and inflammation is involved in the atherosclerosis process. | 27420776 |
| Inflammation | Altered Intercellular Communication | Conclusions sedentary lifestyle and high-carbohydrate intake were associated with low-grade chronic inflammation and cardiovascular risk in postmenopause. | 27420776 |
| Refractory anemias, Rheumatoid Arthritis, Have Autoimmune or Inflammatory Condition, Autoimmune Diseases | Altered Intercellular Communication | Since dendritic cells (DC) are involved in the development of autoimmune inflammation, researchers consider DC both as target cells for specific therapy of rheumatoid arthritis (RA) and as candidate cells for the development of cell-based methods to treat autoimmune diseases. | 27421624 |
| Inflammation, Impaired T cell function, Diabetes Mellitus, Non-Insulin-Dependent | Altered Intercellular Communication | LIGHT/TNFSF14 is increased in patients with type 2 diabetes mellitus and promotes islet cell dysfunction and endothelial cell inflammation in vitro. | 27421726 |
| vascular inflammations, Metabolic Diseases, Diabetes Mellitus, Non-Insulin-Dependent | Altered Intercellular Communication | On the basis of its role in vascular inflammation and in metabolic disorders, we hypothesised that the TNF superfamily (TNFSF) member 14 (LIGHT/TNFSF14) could be involved in the pathogenesis of type 2 diabetes mellitus. | 27421726 |
| vascular inflammations, Diabetes Mellitus, Non-Insulin-Dependent | Altered Intercellular Communication | Our in vitro findings suggest that LIGHT may contribute to the progression of type 2 diabetes mellitus by attenuating insulin secretion in pancreatic islet cells and by contributing to vascular inflammation. | 27421726 |
| Inflammation, Cerebellar Ataxia | Altered Intercellular Communication | One month after IL-7 therapy, he developed worsening ataxia and CSF inflammation, which raised suspicion for immune reconstitution inflammatory syndrome. | 27421731 |
| Inflammation, Autoimmune Thyroid Disease Pathway, Edema | Altered Intercellular Communication | The human orbit is an environment that is vulnerable to inflammation and edema in the setting of autoimmune thyroid disease. | 27423310 |
| Inflammation, Malignant Neoplasms, Ulcer | Altered Intercellular Communication | A surgical biopsy of the ulcer showed inflammation with no evidence of malignancy. | 27423333 |
| Inflammation, Carcinogenesis, Obesity | Altered Intercellular Communication | Obesity is a known generator of chronic inflammation but has an uncertain role in ovarian carcinogenesis and survival. | 27423378 |
| Inflammation, Atherosclerosis, Sleep disturbances, Endothelial dysfunction, Hypertension, CTCAE | Altered Intercellular Communication | Numerous biological pathways linking sleep disturbances to atherosclerosis have been identified, such as insulin resistance, inflammation, hypertension, and endothelial dysfunction. | 27423537 |
| Inflammation | Altered Intercellular Communication | Idiopathic hypertrophic cranial pachymeningitis (IHCP) is an uncommon disease of unknown etiology characterized by thickening of the cerebral dura mater with possible associated inflammation. | 27423594 |
| Unknown (origin) (qualifier value), Inflammation | Altered Intercellular Communication | Hypertrophic Pachymeningitis (HP) denotes inflammation and thickening of the dura mater that can be idiopathic or secondary to a wide variety of conditions. | 27423604 |
| Refractory anemias, Inflammation, Rheumatoid Arthritis, Degenerative polyarthritis | Altered Intercellular Communication | Inhomogeneity of immune cell distribution in the synovial sublining layer was analyzed in order to improve our mechanistic understanding of synovial inflammation and explore potential refinements for histological biomarkers in rheumatoid arthritis (RA) and osteoarthritis (OA). | 27424032 |
| Inflammation, Atelectasis, Pneumonia, Acute Lung Injury, Respiratory Failure | Altered Intercellular Communication | The fact that patients without effusion, atelectasis, or pneumonia may develop respiratory failure, suggests that acute lung injury, possibly associated with systemic inflammation, may be important. | 27424478 |
| Occluded, Bacterial resistance, Inflammation | Altered Intercellular Communication | These conditions share common pathophysiologic features, including follicle occlusion, bacterial overgrowth, severe suppurative inflammation, scarring, and sinus tract formation. | 27425163 |
| Cerebrovascular accident | Altered Intercellular Communication | A previous animal study demonstrated an increased expression of the endocannabinoid receptor 1 (CB1R) in the penumbra area surrounding the ischemic core, suggesting a crucial role in inflammation/reperfusion after stroke. | 27425766 |
| Inflammation | Altered Intercellular Communication | Macrophage Migration Inhibitory Factor (MIF) is important to trigger inflammation processes. | 27426952 |
| Inflammation, anaphylaxis | Altered Intercellular Communication | This toxin and others can lead to reactions ranging from local inflammation to anaphylaxis. | 27427329 |
| Inflammation, Fibrosis Assessment | Altered Intercellular Communication | The right dura mater was thickened due to fibrosis and inflammation. | 27427341 |
| Inflammation, Traumatic injury, Atherosclerosis | Altered Intercellular Communication | The likely etiology of VAAs is uncertain, which includes atherosclerosis, trauma, and inflammation. | 27427351 |
| Inflammation, Osteochondritis Dissecans, Acute postoperative pain, Traumatic injury | Altered Intercellular Communication | No significant difference in the plasma CRP level was found between groups P and C. Parecoxib sodium decreases POCD incidence after total knee arthroplasty in elderly patients and may explain how this drug suppresses inflammation and acute postoperative pain caused by surgical trauma. | 27428192 |
| Inflammation, Hypertensive (finding) | Altered Intercellular Communication | Both sex groups showed a mean hypertensive state and low-grade inflammation (C-reactive protein > 3 mg/L). | 27428354 |
| ARCN1 gene, Bacterial Infections | Altered Intercellular Communication | The pathogenesis of COPD is thought to involve bacterial infections and inflammations. | 27428540 |
| Inflammation, Skin Erosion | Altered Intercellular Communication | In 9 patients, the severity of wound complications such as inflammation or skin erosion decreased both in frequency and magnitude (eg, affected area). | 27428564 |
| Rheumatoid Arthritis | Altered Intercellular Communication | Reciprocal Relationship Between Sleep Macrostructure and Evening and Morning Cellular Inflammation in Rheumatoid Arthritis. | 27428854 |
| Refractory anemias, Inflammation, Rheumatoid Arthritis | Altered Intercellular Communication | This study examined the reciprocal associations between sleep macrostructure and levels of cellular inflammation in rheumatoid arthritis (RA) patients and controls. | 27428854 |
| Refractory anemias, Inflammation | Altered Intercellular Communication | RA patients show evidence of sleep fragmentation, greater sleep depth, and higher levels of cellular inflammation. | 27428854 |
| Pain Distress Question, Inflammation, Hypersensitivity, Necrosis | Altered Intercellular Communication | Adverse reactions related to ethanolamine oleate (EO) include pain during injection, redness, inflammation, tissue necrosis, and allergic reaction. | 27428925 |
| Inflammation, Traumatic injury | Altered Intercellular Communication | Recent studies have demonstrated that surgical trauma leads to inflammation of the pancreatic remnant, which precedes PPDC. | 27429037 |
| Inflammation | Altered Intercellular Communication | Inflammation may be an important mediator of PPDC. | 27429037 |
| Inflammation, Erythema, Edema | Altered Intercellular Communication | Persistent inflammation was defined as the presence of edema, erythema, and discomfort for at least 28 days. | 27429223 |
| Inflammation, Ruptured simple cyst | Altered Intercellular Communication | Persistent inflammation was found in 1 spontaneous cyst rupture case (50%) and 1 surgically ruptured cyst (3.7%). | 27429223 |
| Inflammation, Dermoid Cyst, Rupture | Altered Intercellular Communication | Persistent inflammation is uncommon after surgical rupture of dermoid cysts, but likely after spontaneous rupture. | 27429223 |
| Inflammation | Altered Intercellular Communication | Chronic inflammation in the middle ear may result in functional impairment of the chorda tympani nerve, which carries taste from the anterior two-thirds of the tongue. | 27430226 |
| Inflammation, Brain Injuries, Subarachnoid Hemorrhage | Altered Intercellular Communication | The Role of Platelet Activation and Inflammation in Early Brain Injury Following Subarachnoid Hemorrhage. | 27430874 |
| Inflammation, Microthrombosis, Ischemia | Altered Intercellular Communication | Animal studies suggest that platelet activation and inflammation with subsequent microthrombosis and ischemia may be a mechanism of EBI. | 27430874 |
| ACSM3 gene, Inflammation | Altered Intercellular Communication | Platelet activation [thromboelastography maximum amplitude (MA)] and inflammation [C-reactive protein (CRP)] were measured serially over time during the first 72 h following SAH onset. | 27430874 |
| ACSM3 gene, Inflammation, Noninfiltrating Intraductal Carcinoma | Altered Intercellular Communication | Platelet activation and inflammation occur acutely after SAH and are associated with worse EBI, DCI and poor 3-month functional outcomes. | 27430874 |
| Nonulcer dyspepsia, Dysautonomia, Familial, Inflammation, physiopathological | Altered Intercellular Communication | Functional dyspepsia (FD) susceptibility might be influenced by polymorphisms of genes related to inflammation (CD14, macrophage migration inhibitory factor [MIF]), motor (GNB3), and sensory dysfunction (GNB3, TRPV1). | 27430937 |
| Inflammation | Altered Intercellular Communication | Polymorphonuclear neutrophils play a pivotal role in inflammation and atherogenesis. | 27430968 |
| Inflammation, Vascular Diseases | Altered Intercellular Communication | Human neutrophil peptides (HNPs) or alpha (a)-defensins are cysteine-rich cation polypeptides that are produced and released from activated polymorphonuclear neutrophil granules during septic inflammation and acute coronary vascular disorders. | 27430968 |
| Inflammation, Observation Method - Coagulation | Altered Intercellular Communication | Mediators of inflammation, coagulation and fibrinolysis were compared by a univariate analysis. | 27432091 |
| Inflammation | Altered Intercellular Communication | The complement cascade terminates in the cell-surface assembly of membrane attack complexes (MACs), which promote inflammation by causing aberrant signal transduction. | 27432952 |
| Degenerative polyarthritis, Inflammation | Altered Intercellular Communication | Interleukin-29 Enhances Synovial Inflammation and Cartilage Degradation in Osteoarthritis. | 27433031 |
| Degenerative polyarthritis, Inflammation | Altered Intercellular Communication | Inflammation also contributes to the pathogenesis of osteoarthritis (OA). | 27433031 |
| Degenerative polyarthritis, Inflammation | Altered Intercellular Communication | In conclusion, IL-29 stimulates inflammation and cartilage degradation by OA FLS, indicating that this cytokine is likely involved in the pathogenesis of OA. | 27433031 |
| Arterial Stiffness, Inflammation, Damage, Coronary Artery Disease | Altered Intercellular Communication | Early Biomarkers of Renal Damage in Relation to Arterial Stiffness and Inflammation in Male Coronary Artery Disease Patients. | 27433796 |
| Arterial Stiffness, Inflammation, Coronary Artery Disease | Altered Intercellular Communication | Our aim was to evaluate their relationships with arterial stiffness and inflammation in coronary artery disease (CAD) patients and in clinically healthy controls. | 27433796 |
| Inflammation, Inflammatory disorder | Altered Intercellular Communication | MMPs play a role in modulating inflammation and their impact in many inflammatory diseases has been investigated. | 27434116 |
| smooth muscle contraction, Inflammation, Fibrosis Assessment, Lower Urinary Tract Symptoms | Altered Intercellular Communication | Although inflammation and abnormal smooth muscle contractions are known to play key roles in the development of LUTS, tissue fibrosis may also be an important and previously unrecognized contributing factor. | 27434301 |
| Inflammation, Pain Distress Question | Altered Intercellular Communication | Although lubricin plays a role in controlling inflammation and pain as well as being a mechanical lubricant, clinical relevance of lubricin concentration in synovial fluid (SF) is unknown. | 27435056 |
| Myocarditis, CTCAE 5.0, Myocarditis | Altered Intercellular Communication | In patients with acute myocarditis, CMR markers of myocardial inflammation demonstrated a rapid and continuous decrease over several follow-up examinations. | 27436306 |
| Myocarditis, CTCAE 5.0 | Altered Intercellular Communication | Myocardial T1 and T2 relaxation times were the only parameters of active inflammation/edema that could discriminate between myocarditis patients and control subjects even at a convalescent stage of the disease. | 27436306 |
| Inflammation, Urinary Bladder, Underactive | Altered Intercellular Communication | We investigated urothelial barrier deficits, suburothelial inflammation and sensory proteins expressed in the bladder mucosa of patients with detrusor underactivity. | 27436428 |
| Inflammation, physiopathological, Urinary Bladder, Underactive | Altered Intercellular Communication | Urothelial dysfunction, increased suburothelial inflammation and altered sensory protein expressions in bladder mucosa were prominent in patients with detrusor underactivity. | 27436428 |
| Inflammation, Peripheral Arterial Diseases | Altered Intercellular Communication | Inflammation plays a pivotal role in peripheral artery disease (PAD). | 27436494 |
| Inflammation, diabetic | Altered Intercellular Communication | PTX-3 was not correlated with other markers of inflammation (IL-1, TNF-a and hsCRP) and diabetic metabolic parameters (hbA1c, C-peptide, insulin and HOMA-IR). | 27436699 |
| Inflammation | Altered Intercellular Communication | PTX-3 that increases similar to other markers of inflammation (IL-1, TNF-a) is a better inflammatory marker than hsCRP. | 27436699 |
| Inflammation, Endothelial dysfunction | Altered Intercellular Communication | Activated platelets are enlarged, and contain vasoactive and prothrombic factors that aggravate systemic inflammation and endothelial dysfunction. | 27437641 |
| Ischemia, Inflammation, Hypertrophy | Altered Intercellular Communication | After orthotopic heart transplantation (OHT), the allograft undergoes characteristic alterations in myocardial structure, including hypertrophy, increased ventricular stiffness, ischemia, and inflammation, all of which may decrease overall graft survival. | 27437924 |
| Inflammation, Diabetes Mellitus, Obesity, Cardiovascular Diseases | Altered Intercellular Communication | Inflammation may contribute to pathological associations among obesity, diabetes mellitus, and cardiovascular disease. | 27438317 |
| Airway structure | Altered Intercellular Communication | Fractional exhaled nitric oxide (FeNO) has been used as a marker for airway inflammation. | 27438353 |
| Abnormal degeneration | Altered Intercellular Communication | Using human and mouse MPs in vitro and inflammation-prone Cx3cr1(GFP/GFP) mice in vivo, we demonstrate that MP-derived IL-1b leads to severe CS degeneration. | 27438413 |
| Retinitis, methyldopa, Hyperplastic Polyp, Daytime, Retinitis Pigmentosa | Altered Intercellular Communication | Inhibiting subretinal MP accumulation or Il-1b might protect the CS and help preserve high acuity daytime vision in conditions characterized by subretinal inflammation, such as AMD and RP. | 27438413 |
| Inflammation, Fibrosis Assessment, Capsulitis | Altered Intercellular Communication | As such, TNC, FN1 and TGFb1 receptor I may also play roles in adhesive capsulitis by contributing to capsule inflammation and fibrosis. | 27438566 |
| Intraocular inflammation, Intraocular Lymphoma | Altered Intercellular Communication | Intraocular lymphoma often masquerades as intraocular inflammation, resulting in delayed or misdiagnosis with subsequent inappropriate management. | 27438792 |
| Aneurysm, Behavior, Inflammation | Altered Intercellular Communication | We used high-resolution magnetic resonance imaging (HRMRI) to investigate the aneurysm wall in an effort to identify evidence of inflammation invasion and define its relationship with aneurysm behavior. | 27438805 |
| Aneurysm, Inflammation | Altered Intercellular Communication | The aneurysm's wall enhancement and evidence of inflammation invasion were determined. | 27438805 |
| Inflammation, Fibrosis Assessment | Altered Intercellular Communication | In rats, both T1 and ADC correlated well with fibrosis and inflammation showing a difference between normal and diseased kidneys. | 27439482 |
| Interstitial inflammation | Altered Intercellular Communication | In KARs, MRI indices were not sensitive to interstitial inflammation. | 27439482 |
| Granulomatous inflammation, Pyelitis | Altered Intercellular Communication | Pseudotuberculous granulomatous pyelitis is a rarely reported entity, characterized by severe granulomatous inflammation limited predominantly to the renal pelvis. | 27440812 |
| allergic inflammation | Altered Intercellular Communication | Several changes in miRNA expression have been found as a result of the buildup phase of wasp VIT, with lower expression of some miRNAs involved in allergic inflammation and higher expression of those possibly involved in tolerance induction. | 27441833 |
| Inflammation, Obstructive Ureterocele, Hyperplasia | Altered Intercellular Communication | Histological investigations have confirmed the neointimal venous hyperplasia as a major pathological finding in stenotic lesions of AVF failure, due to local inflammation, oxidative stress and migration and proliferation of myofibroblasts, fibroblasts and endothelial cells. | 27442395 |
| Inflammation | Altered Intercellular Communication | The absence of TGFb expression in majority of our patients could suggest that inflammation and oxidative stress are developing later, after vascular access surgery. | 27442395 |
| Inflammation | Altered Intercellular Communication | Presence of dermal inflammation and melanoderma may contribute to atypical clinical appearance leading to biopsy despite their small clinical size. | 27442449 |
| Hepatic inflammation, Non-alcoholic Fatty Liver Disease | Altered Intercellular Communication | In a murine model for hepatic inflammation during non-alcoholic fatty liver disease (NAFLD), increased antibody levels targeting OSE were found to be protective. | 27443391 |
| Inflammation, Liver damage, Obesity | Altered Intercellular Communication | Plasma IgM titers towards the P1 mimotope demonstrated an inverse correlation with markers for obesity, systemic inflammation, and liver damage. | 27443391 |
| vascular inflammations, Pulmonary Emphysema, Diabetes Mellitus | Altered Intercellular Communication | Leukocyte-endothelial adhesion is a critical early step in chronic vascular inflammation associated with diabetes, emphysema, and aging. | 27444067 |
| Inflammation, Temporal Arteritis | Altered Intercellular Communication | Is all inflammation within temporal artery biopsies temporal arteritis? | 27445262 |
| Inflammation, vascular inflammations | Altered Intercellular Communication | As ischemic events occur in patients with non-temporal artery--based inflammation, it has been recommended that any vascular inflammation within TABs be treated with corticosteroids. | 27445262 |
| Inflammation, Temporal Arteritis | Altered Intercellular Communication | TABs without transmural temporal arteritic damage accessioned between 2002 and 2012 were reviewed for inflammation (>15 perivascular lymphocytes) involving small blood vessels and/or temporal artery adventitia. | 27445262 |
| Sleep Apnea, Obstructive | Altered Intercellular Communication | Effect of Continuous Positive Airway Pressure on Airway Inflammation and Oxidative Stress in Patients with Obstructive Sleep Apnea. | 27445526 |
| Airway structure, Sleep Apnea, Obstructive, Osage language | Altered Intercellular Communication | Airway inflammation and oxidative stress may be linked in obstructive sleep apnea (OSA) patients. | 27445526 |
| Airway structure, Osage language | Altered Intercellular Communication | Our study demonstrates that CPAP therapy yields clinical benefits by reducing upper airway inflammation and oxidative stress in OSA patients. | 27445526 |
| Pain Distress Question, Damage, Inflammation | Altered Intercellular Communication | Paroxysmal pain was more severe, suggesting that neural damage might be aggravated by obesity-associated inflammation. | 27445603 |
| Chronic pain | Altered Intercellular Communication | Individuals with chronic pain had a greater risk factor composite than individuals without chronic pain controlling for covariates and after excluding inflammation-related health conditions (p < 0.001). | 27445627 |
| ARCN1 gene, Inflammation, Chronic Obstructive Airway Disease | Altered Intercellular Communication | About 20% of cigarette smokers develop chronic obstructive pulmonary disease (COPD) due to smoke-induced irreversible damage and sustained inflammation of the airway epithelium. | 27447246 |
| Inflammation, Diabetes Mellitus, Non-Insulin-Dependent | Altered Intercellular Communication | Type 2 diabetes patients (T2D) have a considerably higher cardiovascular risk, which is closely associated with systemic inflammation, and an accompanying pathologic coagulation system. | 27447972 |
| Inflammation, Damage | Altered Intercellular Communication | Biomarker levels indicative of inflammation and renal damage were lower in the young, although they exhibited higher BNP levels than older patients. | 27448534 |
| Inflammation | Altered Intercellular Communication | Inflammation mediated through TNF alpha and TGF beta 1 may represent an important component of an inflammatory response that partially drives the pathophysiology of HFpEF. | 27448535 |
| Exanthema, Discoloration of skin, Inflammatory disease of mucous membrane, Xerostomia, Palmar-plantar erythrodysesthesia syndrome, Photosensitivity of skin, Hypothyroidism, Alopecia, CTCAE, Erythema, Dyspepsia, Anorexia, Dry skin, Peripheral edema, Dysgeusia, CTCAE, Hypertension, CTCAE, Fatigue | Altered Intercellular Communication | The most common AEs in patients taking sunitinib were fatigue (70 %), hand-foot syndrome (62 %), skin rash (58 %), mucosal inflammation (58 %), anorexia (42 %), skin discoloration (42 %), followed by dry mouth, dysgeusia, dyspepsia, dry skin, dry mouth, hair color changes, hypothyroidism, alopecia, oral pain/stomatitis, hypertension, decreased weight, photosensitivity, peripheral edema, erythema, and others. | 27448573 |
| Inflammation, Cerebrovascular accident | Altered Intercellular Communication | Background Although the role of microparticles was recently implicated in stroke pathophysiology, the association between microparticles and inflammation is still not fully understood. | 27448592 |
| Degenerative polyarthritis, Inflammation | Altered Intercellular Communication | Current description of osteoarthritis includes the involvement of synovial inflammation. | 27449198 |
| Degenerative polyarthritis, Inflammation, Tissue damage | Altered Intercellular Communication | During osteoarthritis, synovial fibroblasts exposed to anomalous mechanical forces and an inflammatory microenvironment release factors such as a disintegrin and metalloproteinase with thrombospondin motifs (ADAMTS) metalloproteinases that mediate tissue damage and perpetuate inflammation. | 27449198 |
| Refractory anemias, Inflammation | Altered Intercellular Communication | The color fraction tends to be increased in wrist and MCP3 joints which indicate the increased blood flow pattern and color Doppler activity as part of inflammation in hand joints of RA. | 27449351 |
| Inflammation, Peripheral Arterial Diseases | Altered Intercellular Communication | Biochemical indices of oxidative stress and inflammation in the evaluation of peripheral artery disease. | 27449545 |
| Deficit, Inflammation, Excitation, Neurotoxicity Syndromes | Altered Intercellular Communication | Related pathophysiological processes reflected by these metabolites are energy deficit, inflammation, nervous excitation and neurotoxicity. | 27450370 |
| Autoimmune Diseases, Vasculitis, AAVS1 gene, Inflammation | Altered Intercellular Communication | The ANCA-associated vasculitides (AAV) are systemic autoimmune inflammatory disorders characterised by necrotising inflammation affecting small to medium-sized blood vessels. | 27450392 |
| Inflammation, Primary malignant neoplasm | Altered Intercellular Communication | The neutrophil-to-lymphocyte ratio (neutrophil count divided by lymphocyte count) is a marker of inflammation associated with poor cancer outcomes. | 27450715 |
| Inflammation, Obesity, Coronary heart disease | Altered Intercellular Communication | The impact of inflammation on the obesity paradox in coronary heart disease. | 27453423 |
| Inflammation, Metabolic Diseases, Primary malignant neoplasm, Nerve Degeneration, Muscular Atrophy, Disease | Altered Intercellular Communication | These pathways are deregulated in human diseases, including cancer, neurodegeneration, metabolic disorders, muscle atrophy, ageing, and inflammation, reflecting the importance of mitophagy as a cellular housekeeping function. | 27453450 |
| Inflammation | Altered Intercellular Communication | The consequent progressive formation of ochronotic aggregates generate a severe condition of oxidative stress and inflammation in all the affected areas. | 27454006 |
| Inflammation, Neoplasms | Altered Intercellular Communication | Some of these findings were due to inflammation, whereas in most cases, uptake was seen in benign tumors of the brain or in the endocrine or exocrine glands. | 27454592 |
| Rheumatoid Arthritis, Inflammation, Inflammatory disorder | Altered Intercellular Communication | In autoinflammatory diseases, such as rheumatoid arthritis, characterized by inflammation and joint involvement, autoantibodies against oxidative post-translationally modified (oxPTM) collagen type I (CI) and type II (CII) were detected. | 27454862 |
| Inflammation, Congestion | Altered Intercellular Communication | Endoscopic findings ranged from normal gastric mucosa to severe inflammation, congestion, and friability. | 27454942 |
| Inflammation, Chronic disease of ear, Erosion of bone | Altered Intercellular Communication | Inflammation due to chronic ear disease can cause bony erosion of the carotid artery and Fallopian canals, making them more vulnerable during surgery. | 27455393 |
| Inflammation, Dysglycemia, ETV3 wt Allele, diabetic | Altered Intercellular Communication | Inflammation, matrix metalloproteinases and dysglycemia markers are not expressed in isolation but rather concurrently and are continuously interacting with each other, in MetS and diabetics patients. | 27455450 |
| Inflammation, Arthritis, Psoriatic | Altered Intercellular Communication | These findings have important implications for understanding the role of MHC alleles in directing the adaptive immune response to mediate the inflammation responsible for psoriatic arthritis. | 27455857 |
| Granulomatous inflammation | Altered Intercellular Communication | Two skin biopsies and a biopsy of the olecranon bursa revealed granulomatous inflammation. | 27456320 |
| Diabetes Mellitus, Insulin-Dependent, Inflammation, IGHD1-7 gene | Altered Intercellular Communication | Patients with type 1 diabetes (DM1) have distinct gut microbiota in comparison to non-diabetic individuals, and it has been linked to changes in intestinal permeability, inflammation and insulin resistance. | 27456494 |
| Inflammation, IGHD1-7 gene | Altered Intercellular Communication | Prebiotics are a potentially novel, inexpensive, low-risk treatment addition for DM1 that may improve glycemic control by changes in gut microbiota, gut permeability and inflammation. | 27456494 |
| Inflammation, Heat-Shock Proteins 70, Chronic sinusitis | Altered Intercellular Communication | HSP70 is associated with the severity of inflammation in chronic rhinosinusitis. | 27456583 |
| Airway structure | Altered Intercellular Communication | Nasal secretions include cytokines and inflammatory mediators that are involved in the pathogenesis of upper airway inflammation. | 27456583 |
| Inflammation, Myelosuppression | Altered Intercellular Communication | The observed myelosuppression was not driven by inflammation and thus other mechanisms are at play. | 27456951 |
| Acute inflammation, Neoplasms | Altered Intercellular Communication | Restaging computed tomography at the time of referral showed findings in the hepatoduodenal ligament and gallbladder fossa concerning residual tumor versus postoperative inflammation. | 27456958 |
| Inflammation, Venous Thrombosis | Altered Intercellular Communication | In BD, the inflammation on vessel walls causes venous thrombosis. | 27457028 |
| Inflammation, Primary malignant neoplasm, Cardiovascular Diseases, Infection, Cerebrovascular accident | Altered Intercellular Communication | A leading hypothesis proposes that increased human life span since 1850 has resulted from decreased exposure to childhood infections, which has reduced chronic inflammation and later-life mortality rates, particularly from cardiovascular disease, stroke, and cancer. | 27457937 |
| Communicable Diseases, Inflammation | Altered Intercellular Communication | Our results do not support the prevailing assertion that exposure to infectious diseases in early life has long-lasting associations with later-life all-cause mortality risk or mortality putatively linked to chronic inflammation. | 27457937 |
| Lower Urinary Tract Symptoms, Benign prostatic hypertrophy, prostatitis | Altered Intercellular Communication | The prevalence of prostatic inflammation (PI) is very frequent in patients affected by benign prostatic hyperplasia (BPH) and lower urinary tract symptoms (LUTS). | 27458062 |
| Non-alcoholic Fatty Liver Disease, ETV3 wt Allele, prostatitis | Altered Intercellular Communication | To investigate the relationship between prostatic inflammation (PI) and the presence of MetS and non-alcoholic fatty liver disease (NAFLD) in a cohort of patients affected by BPH/LUTS. | 27458062 |
| Inflammation, Non-alcoholic Fatty Liver Disease, ETV3 wt Allele | Altered Intercellular Communication | The coexistence of MetS and NAFLD exerted a greater detrimental effect on prostate gland by increasing severity of inflammation. | 27458062 |
| Inflammation | Altered Intercellular Communication | Adipose tissue (AT) inflammation leads to increased free fatty acid (FFA) efflux and ectopic fat deposition, but whether AT dysfunction drives selective fat accumulation in specific sites remains unknown. | 27458255 |
| Orchitis | Altered Intercellular Communication | Most cases of diverticular inflammation are mild and require only medical treatment with liquid diet and antibiotics. | 27458848 |
| Plaque, Atherosclerotic | Altered Intercellular Communication | Similar Impact of Clopidogrel or Ticagrelor on Carotid Atherosclerotic Plaque Inflammation. | 27459273 |
| Plaque, Atherosclerotic | Altered Intercellular Communication | Inhibitors of the P2Y12 receptor, which is involved in platelet activation, may have a direct effect on carotid atherosclerotic plaque inflammation. | 27459273 |
| Inflammation | Altered Intercellular Communication | The initiation and progression of GC are associated with inappropriate immune responses caused by chronic inflammation of the gastric mucosa. | 27459504 |
| Inflammation, Immune System Diseases | Altered Intercellular Communication | Impaired Zn status promotes immune dysfunction, and it has been associated with enhanced chronic inflammation during aging. | 27459881 |
| Inflammation, Cerebrovascular accident | Altered Intercellular Communication | Though the pathophysiological mechanisms are not exactly known, increased inflammation and platelet reactivity could play an important role in the occurrence of stroke during AMI. | 27459905 |
| Inflammation, Cerebrovascular accident | Altered Intercellular Communication | Moreover, these results provide new insights into the potential role played by increased inflammation and platelet reactivity in the occurrence of stroke after AMI. | 27459905 |
| Coronary heart disease | Altered Intercellular Communication | Association of six CpG-SNPs in the inflammation-related genes with coronary heart disease. | 27461004 |
| Inflammation, Coronary heart disease, Choline Dehydrogenase, Mitochondrial | Altered Intercellular Communication | Chronic inflammation has been widely considered to be the major risk factor of coronary heart disease (CHD). | 27461004 |
| Inflammation, Choline Dehydrogenase, Mitochondrial | Altered Intercellular Communication | In conclusion, all the six inflammation-related CpG-SNPs (rs16944, rs2071008, rs12732361, rs2065666, rs9395208, and rs1800686) were associated with CHD in the combined or subgroup tests, suggesting an important role of inflammation in the risk of CHD. | 27461004 |
| Non-necrotizing granulomatous inflammation | Altered Intercellular Communication | It is characterized by a slow onset and invasive organisms with non-granulomatous inflammation seen on histopathology. | 27463614 |
| Inflammation, Benign prostatic hypertrophy, Metabolic Syndrome X | Altered Intercellular Communication | Association between Benign Prostatic Hyperplasia and Neutrophil-Lymphocyte Ratio, an Indicator of Inflammation and Metabolic Syndrome. | 27464069 |
| Inflammation, Lower Urinary Tract Symptoms, ETV3 wt Allele | Altered Intercellular Communication | Here, we aimed at evaluating the role of neutrophil-lymphocyte ratio (NLR), an indicator of inflammation and MetS, in the pathogenesis of LUTS and other BPH-related parameters. | 27464069 |
| Inflammation, fibrogenesis | Altered Intercellular Communication | Galectin-3 (Gal-3), a novel biomarker involved in inflammation, tissue repair and fibrogenesis, might be a valuable predictor of LVR. | 27465055 |
| Inflammation | Altered Intercellular Communication | Patients who have undergone allogeneic stem cell transplantation represent a unique population that may offer novel insight into the pathways involved in radiation-related inflammation. | 27465468 |
| Inflammation, Weight decreased, Hypertension, CTCAE | Altered Intercellular Communication | Heightened surveillance for risk, and adoption of healthy living recommendations specifically directed toward weight reduction, hypertension management, and inflammation control, should be incorporated as a priority for disease prevention and management. | 27465752 |
| Crohn Disease, Fibrosis Assessment, Inflammation, Granuloma | Altered Intercellular Communication | The Lennard-Jones criteria are considered the gold standard for diagnosing Crohn's disease (CD) and include the items granuloma, macroscopic discontinuity, transmural inflammation, fibrosis, lymphoid aggregates and discontinuous inflammation on histology. | 27466047 |
| Granuloma, Fibrosis Assessment, Inflammation | Altered Intercellular Communication | A new index was derived from granuloma, fibrosis, transmural inflammation and macroscopic discontinuity, but excluded lymphoid aggregates and discontinuous inflammation on histology. | 27466047 |
| Inflammation, Ulcerative Colitis | Altered Intercellular Communication | Serum LRG is a novel biomarker for detecting MH during disease course in patients with UC and a surrogate marker of endoscopic inflammation in patients with normal CRP levels. | 27466171 |
| Inflammation, Fibrosis Assessment, Albuminuria, Glomerulosclerosis (disorder) | Altered Intercellular Communication | Instead, accumulation of lipid-containing lamellar bodies in renal tubuli was detected in P4h-tm-/- mice with aging, resulting in inflammation and fibrosis, and later glomerular sclerosis and albuminuria. | 27466183 |
| Inflammation, Breast Carcinoma, Cancer Pain | Altered Intercellular Communication | Poor breast cancer-related quality of life is associated with flattened cortisol rhythms and inflammation in breast cancer survivors and women with advanced disease. | 27466289 |
| Inflammation | Altered Intercellular Communication | Co-existing biliary inflammation was detected in 8 patients. | 27466492 |
| Inflammation, Lobe of liver, Type 1 Autoimmune Pancreatitis, Sclerosis, Damage, Cholestasis | Altered Intercellular Communication | Immunoglobulin G4-hepatopathy, which includes various histopathological lesions encountered in the liver of patients with type I autoimmune pancreatitis, is classified into five histological categories: portal inflammation, large bile duct damage, portal sclerosis, lobular hepatitis, and cholestasis. | 27466793 |
| Inflammation, Diabetes Mellitus, Insulin-Dependent, Choroidal and Ciliary Body Melanoma pT1d TNM Finding v8 | Altered Intercellular Communication | Several studies have evaluated the role of inflammation in type 1 diabetes (T1D). | 27467009 |
| Inflammation, Blood coagulation | Altered Intercellular Communication | This is a significant polypeptide released in pretty much all cells and important for the regulation of cellular events, epithelium formation, inflammation, blood coagulation, and collagen synthesis. | 27467498 |
| Inflammation, Dental Plaque, GDC AJCC Clinical Stage Terminology | Altered Intercellular Communication | ACS is associated with a pan-inflammatory state, and intraplaque features of inflammation correlate with coronary plaque progression. | 27468140 |
| Inflammation | Altered Intercellular Communication | After platelet transfusion, we observed a transient and slight increase in inflammation parameters. | 27468945 |
| Gingivitis | Altered Intercellular Communication | Longitudinal analysis of 6,316 Kuwaiti children revealed that shorter sleep duration and higher salivary glucose levels were both associated with increased gingival inflammation. | 27470068 |
| Inflammation, Depressed mood | Altered Intercellular Communication | This study suggests that stressful events in childhood are associated with shorter TL in middle-aged men and that part of this relation is explained by depressive mood and low grade inflammation. | 27470228 |
| Inflammation, Osteochondritis Dissecans | Altered Intercellular Communication | The pathophysiology of POCD remains elusive, but previous work showed that intravenous lidocaine may be protective against POCD, possibly by modulating cerebral inflammation. | 27470233 |
| Inflammation | Altered Intercellular Communication | This may be a manifestation of reduced cerebral inflammation during cardiopulmonary bypass in response to treatment with lidocaine. | 27470233 |
| Myopia, Inflammation | Altered Intercellular Communication | Role of Chronic Inflammation in Myopia Progression: Clinical Evidence and Experimental Validation. | 27470424 |
| Inflammation, Memory for Designs Test | Altered Intercellular Communication | We found atropine downregulated inflammation in MFD eyes. | 27470424 |
| Myopia, Inflammation | Altered Intercellular Communication | These findings provide clinical and experimental evidence that inflammation plays a crucial role in the development of myopia. | 27470424 |
| Inflammation, "Alzheimers Disease", Data types - Address | Altered Intercellular Communication | It is increasingly becoming accepted that inflammation may play an important role in the pathogenesis of Alzheimer's disease (AD), as several immune-related genes have been associated with AD. | 27470609 |
| Aortic Aneurysm, Aortitis | Altered Intercellular Communication | BACKGROUND Inflammation of the aortic wall, known as aortitis, is a rare clinical entity which is frequently asymptomatic, or identified when the patient presents with an aortic aneurysm or dissection. | 27471062 |
| Inflammation, Fibrosis Assessment, Lung Diseases, Interstitial, Lung Injury | Altered Intercellular Communication | Evidence suggests that lung injury, inflammation and extracellular matrix remodelling precede lung fibrosis in interstitial lung disease (ILD). | 27471206 |
| Liver carcinoma, FAM126A gene | Altered Intercellular Communication | Various inflammation-based prognostic scores have been associated with poor survival in patients with hepatocellular carcinoma (HCC), and neutrophils display important roles. | 27472390 |
| Inflammation, Diabetes Mellitus, Non-Insulin-Dependent, Metabolic Syndrome X, Atherosclerosis | Altered Intercellular Communication | Since changes in some immune system indicators such as leukocyte count and neutrophil to lymphocyte ratio in the blood and Inflammation is directly in relation with the pathogenesis of type 2 diabetes, metabolic syndrome and atherosclerosis, measuring these indicators in patients with type 2 diabetes and comparing them with control group can be a suitable indicator of Inflammation and prognosis of the disease. | 27472870 |
| Inflammation, Diabetes Mellitus, Non-Insulin-Dependent | Altered Intercellular Communication | Considering the findings of current study, we showed the inflammation and the pathogenesis caused by type 2 diabetes can be attributed to neutrophil to lymphocyte ratio. | 27472870 |
| Degenerative polyarthritis, Inflammation, Musculoskeletal Diseases | Altered Intercellular Communication | Osteoarthritis (OA) is a chronic systemic musculoskeletal disorder involving inflammation, immunity, and metabolic alterations. | 27472907 |
| Degenerative polyarthritis, Inflammation, Inflammatory disorder | Altered Intercellular Communication | OA is commonly regarded as non-inflammatory disease; still inflammation is recognized as contributing to the symptoms and progression of OA. | 27472907 |
| Pneumonitis | Altered Intercellular Communication | Low tidal volume ventilation with low PEEP during surgery may induce lung inflammation. | 27473050 |
| Pneumonitis | Altered Intercellular Communication | Low tidal-volume ventilation with low positive end-expiratory pressure may lead to pulmonary inflammation during major surgery such as hepatectomy. | 27473050 |
| Inflammation, Bacterial Infections | Altered Intercellular Communication | Its homeostasis is tightly linked to oxidative stress, bacterial infections and systemic inflammation. | 27473364 |
| Single organ dysfunction, Inflammation, Alcoholic Intoxication, Chronic | Altered Intercellular Communication | Transferrin, TSAT and ferritin differentially correlated with the severity of organ failure, active alcoholism and surrogates of systemic inflammation and macrophage activation. | 27473364 |
| Single organ dysfunction, Inflammation | Altered Intercellular Communication | Lower transferrin (continuous or dichotomized at 87 mg/dL) and consecutively higher TSAT (continuous or dichotomized >41%) indicated increased mortality within 30 days and remained significant after adjustment for organ failure and inflammation in multivariate regression models and across subgroups of patients. | 27473364 |
| Excessive tearing, Inflammation | Altered Intercellular Communication | Clinical symptoms of epiphora settled with topical steroid drops, but the clinical signs of chronic tarsal inflammation persisted until withdrawal of the facial wipes thought to contain the inciting agent, though the exact nature of this remains unclear. | 27473439 |
| Cardiovascular morbidity, Psoriasis | Altered Intercellular Communication | Inflammation of systemic and vascular tissues besides the skin in psoriasis is associated with cardiovascular morbidity and mortality. | 27473449 |
| Inflammation, neuron death, Cerebrovascular accident | Altered Intercellular Communication | Ischemic stroke (IS) usually initiates inflammation and oxidative stress leading to neuronal death. | 27474112 |
| Inflammation, diabetic | Altered Intercellular Communication | Finally, fasting glucose and HbA1c may also be useful indicators for cerebrovascular risk in diabetic patients that may be mediated by low levels of antioxidative defense markers and high inflammation status. | 27474112 |
| Inflammation, Atherosclerotic renal artery stenosis, renal hypoxia | Altered Intercellular Communication | Atherosclerotic renal artery stenosis (ARAS) reduces renal blood flow (RBF), ultimately leading to kidney hypoxia and inflammation. | 27474749 |
| Perihilar Cholangiocarcinoma | Altered Intercellular Communication | Appraisal of inflammation-based prognostic scores in patients with unresectable perihilar cholangiocarcinoma. | 27474781 |
| Primary malignant neoplasm | Altered Intercellular Communication | Inflammation-based prognostic scores are useful prognostic indicators for several types of cancer. | 27474781 |
| Inflammation, Neoplasms | Altered Intercellular Communication | Tumor size greater than 2 mm and inflammation were risks for false-positives. | 27475968 |
| Autoimmune Diseases, Vasculitis, AAVS1 gene, Inflammation | Altered Intercellular Communication | Anti-neutrophil cytoplasmic antibodies (ANCA)-associated vasculitides (AAV) are a group of systemic autoimmune disorders characterized by necrotizing inflammation of small- to medium-sized blood vessels. | 27476166 |
| Inflammation, Osteoporosis, Postmenopausal | Altered Intercellular Communication | Serum FKN concentrations were negatively associated with BMD at femoral neck (r = -0.394, p = 0.004), total hip(r = -0.374, p = 0.006), internal trochanter(r = -0.340, p = 0.013), greater trochanter(r = -0.376, p = 0.006), Ward's triangle(r = -0.343, p = 0.012), L1-L4 lumbar spine(r = -0.339, p = 0.013) and positively associated with VAS (r = 0.321, p = 0.019) and ODI (r = 0.377, p = 0.005) scores, bone turnover makers (TRACP-5b:r = 0.341, p = 0.012; NTX:r = 0.364, p = 0.007)as well as inflammation markers (IL-1b: r = 0.396, p = 0.003; IL-6:r = 0.355, p = 0.009) in postmenopausal osteoporotic patients. | 27476376 |
| Fear (Mental Process), Inflammation, Alopecia, CTCAE, Peeling of skin | Altered Intercellular Communication | Dermatological examination of the capillitium found a zone of incomplete alopecia in the frontoparietal and parietotemporal area, without inflammation, desquamation, and scaring. | 27477178 |
| Inflammation | Altered Intercellular Communication | On histologic examination, there are typically increased numbers of catagen and telogen hairs without evidence of inflammation. | 27477178 |
| Airway structure, mucus secretion | Altered Intercellular Communication | Cold-inducible RNA-binding protein mediates airway inflammation and mucus hypersecretion through a post-transcriptional regulatory mechanism under cold stress. | 27477308 |
| ARCN1 gene, Airway structure | Altered Intercellular Communication | In this study, we showed that CIRP gene and protein levels were significantly increased in patients with COPD and in rats with chronic airway inflammation compared with healthy subjects. | 27477308 |
| Fever, Acute inflammation, Neoplasms, Back Pain | Altered Intercellular Communication | A 63-year-old man with a jugular tumor in the skull base was referred to our hospital for an evaluation of pyrexia, back pain, and acute inflammation. | 27477424 |
| Steatohepatitis, Non-alcoholic Fatty Liver Disease, Inflammation | Altered Intercellular Communication | The complement component C5 promotes liver steatosis and inflammation in murine non-alcoholic liver disease model. | 27477770 |
| Inflammation, Adrenoleukodystrophy | Altered Intercellular Communication | Considering that component C5 is a central mediator of inflammation, we investigated the role of C5 in the establishment of NALD. | 27477770 |
| Fatty degeneration | Altered Intercellular Communication | Again, B6 C5(+) HFDG-fed mice developed more steatosis, liver centro-lobular inflammation and presented higher levels of liver IL-1b, IL-12p70, IL-17 and TFG-b than B6 C5(-) mice under the same conditions. | 27477770 |
| Steatohepatitis, Inflammation, Adrenoleukodystrophy | Altered Intercellular Communication | We concluded that murine C5 contributes effectively to liver steatosis and inflammation in NALD pathogenesis. | 27477770 |
| Inflammation, Rheumatoid Arthritis | Altered Intercellular Communication | Increased inflammation and disease activity among current cigarette smokers with rheumatoid arthritis: a cross-sectional analysis of US veterans. | 27477806 |
| Maxillary Sinusitis, Inflammatory abnormality of the eye, Ethmoid Sinusitis | Altered Intercellular Communication | Thirty-nine (17.8%) of 218 patients showed either maxillary sinusitis or ethmoidal sinusitis and 32 (14.7%) of 218 patients presented with periocular inflammation. | 27478350 |
| Intraocular inflammation | Altered Intercellular Communication | The records of consecutive patients with intraocular inflammation of unknown etiology were reviewed. | 27478352 |
| Intraocular inflammation | Altered Intercellular Communication | OT is a common cause of intraocular inflammation in the tertiary hospital setting. | 27478352 |
| Inflammation, Overweight | Altered Intercellular Communication | The Presence and Duration of Overweight Are Associated with Low-Grade Inflammation in Prepubertal Chilean Children. | 27478998 |
| Inflammation, Overweight | Altered Intercellular Communication | Overweight is associated with low-grade inflammation, but it is under debate whether the effect of fat mass accumulation is acute or chronic. | 27478998 |
| Necrotizing granulomatous inflammation, Carcinoma, Thoracic lymphadenopathy | Altered Intercellular Communication | The Intranodal Presence of Coexisting Granulomatous Inflammation and Carcinoma During Transbronchial Needle Aspiration of Intrathoracic Lymphadenopathy. | 27479015 |
| Inflammation, Malignant Neoplasms | Altered Intercellular Communication | The presence of nodal granulomatous inflammation in patients with underlying malignancy is well reported. | 27479015 |
| Granulomatous inflammation, Malignant Neoplasms | Altered Intercellular Communication | However, review of 3 recent large trials of endobronchial ultrasound-guided transbronchial needle aspiration in patients with granulomatous inflammation and malignancy did not identify the presence of coexisting, intranodal malignancy, and granulomatous inflammation, rather these diagnoses remained nodally exclusive. | 27479015 |
| Inflammation, Carcinoma | Altered Intercellular Communication | We present a case of coexisting granulomatous inflammation and metastatic carcinoma within the same lymph node aspirates, reviewing the potential diagnostic pitfalls and implications of this rare occurrence. | 27479015 |
| Communicable Diseases, Inflammation, Disease | Altered Intercellular Communication | When it is carried out in cases of stone disease, however, it is frequently not a "simple" technique owing to the presence of significant inflammation and infection. | 27479686 |
| Inflammation | Altered Intercellular Communication | In young patients, the authors observed multiple, small calcified bodies within the dermis surrounded by chronic inflammation and granulomatous foreign body reaction. | 27479867 |
| Fibrous, Chronic inflammation | Altered Intercellular Communication | On the other hand, in elderly patients, lesions were characterized by a single, large, well-demarcated amorphous calcified deposit surrounded by fibrous tissue, without chronic inflammation or foreign body reaction. | 27479867 |
| Inflammation, "Alzheimers Disease", Data types - Address | Altered Intercellular Communication | We aimed to characterize endoplasmic reticulum stress, inflammation, and Alzheimer's disease (AD) related markers in peripheral blood mononuclear cells (PBMCs) from males with varied BMI; and to explore whether high glucose and fatty acids (FFAs) might be critical factors for inducing metabolic alterations in PBMCs under obese condition. | 27481183 |
| Sepsis, Inflammation, Lymphohistiocytosis, Hemophagocytic | Altered Intercellular Communication | Hemophagocytic lymphohistiocytosis (HLH) is a life-threatening condition characterized by uncontrolled inflammation and has common clinical and laboratory features with sepsis. | 27481757 |
| Inflammation, Autonomic nervous system disorders, Diabetes Mellitus | Altered Intercellular Communication | Associations between cardiovascular autonomic dysfunction and subclinical inflammation, both risk factors of diabetic comorbidities and mortality, have been proposed in non-diabetic populations, while data for type 1 and type 2 diabetes are conflicting. | 27481890 |
| Autonomic nervous system disorders, Diabetes Mellitus | Altered Intercellular Communication | Our aim was to investigate associations between inflammation-related biomarkers and cardiac autonomic dysfunction in patients with diabetes. | 27481890 |
| Inflammation, Diabetes Mellitus, Non-Insulin-Dependent, Autonomic nervous system disorders, Diabetes Mellitus | Altered Intercellular Communication | We characterised the associations between seven biomarkers of subclinical inflammation and cardiac autonomic dysfunction based on heart rate variability and cardiovascular autonomic reflex tests (CARTs) in 161 individuals with type 1 and 352 individuals with type 2 diabetes (time since diagnosis of diabetes <1 year). | 27481890 |
| Inflammation, Diabetes Mellitus, Non-Insulin-Dependent, Autonomic nervous system disorders | Altered Intercellular Communication | Biomarkers of inflammation were differentially associated with diminished cardiac autonomic dysfunction in recent-onset type 2 diabetes. | 27481890 |
| Myocardial fibrosis, vascular inflammations | Altered Intercellular Communication | In addition, patients in the omega-3 fatty acid arm underwent significant reductions in serum biomarkers of systemic and vascular inflammation and myocardial fibrosis. | 27482002 |
| Inflammation, Fibrosis Assessment, Ventricular Remodeling, Acute myocardial infarction, Infarction | Altered Intercellular Communication | Treatment of patients with acute myocardial infarction with high-dose omega-3 fatty acids was associated with reduction of adverse left ventricular remodeling, noninfarct myocardial fibrosis, and serum biomarkers of systemic inflammation beyond current guideline-based standard of care. | 27482002 |
| Inflammation, Colorectal Carcinoma | Altered Intercellular Communication | The role of diet-associated inflammation in colorectal cancer is of interest. | 27483316 |
| Inflammation, Colorectal Carcinoma | Altered Intercellular Communication | Results from this study suggest that diet-associated inflammation may increase the risk of colorectal cancer, and this effect may differ by certain factors, such as anatomical site, age, sex, and lifestyle. | 27483316 |
| Suicidal behavior, Inflammation, Depression, CTCAE | Altered Intercellular Communication | Emerging evidence suggests that inflammation has a key role in depression and suicidal behavior. | 27483383 |
| Gingivitis | Altered Intercellular Communication | Most of the participants presented with gingival inflammation, which was less in 12-year-old females. | 27484595 |
| Refractory anemias, Rheumatoid Arthritis, Periodontitis | Altered Intercellular Communication | Rheumatoid arthritis (RA) and periodontitis are common chronic inflammatory conditions. | 27484603 |
| hormone deficiency, Immune System Diseases | Altered Intercellular Communication | Growth hormone is important for the development and function of the immune system, but there is controversy on whether growth hormone deficiency is associated to immune disorders. | 27484773 |
| Inflammation | Altered Intercellular Communication | Chronic inflammation has been associated with the development of MM in rare instances and these three cases suggest that CD with transmural inflammation may also be a precursor. | 27484913 |
| Inflammation, Carcinogenesis | Altered Intercellular Communication | The precise role of CD-related transmural inflammation in the carcinogenesis of peritoneal MM remains to be determined. | 27484913 |
| Synovitis, Inflammation, Rheumatoid Factor, Tenosynovitis | Altered Intercellular Communication | We performed cross-sectional analysis of the association of ACPA, rheumatoid factor (RF) and anti-carbamylated protein (anti-CarP) antibodies with BME and other types of inflammation (synovitis, tenosynovitis) detected by magnetic resonance imaging (MRI). | 27485323 |
| Barrett Esophagus | Altered Intercellular Communication | Germline variation in inflammation-related pathways and risk of Barrett's oesophagus and oesophageal adenocarcinoma. | 27486097 |
| Degenerative polyarthritis, Inflammation | Altered Intercellular Communication | Local and systemic inflammation is considered an important contributor to OA pathogenesis. | 27486097 |
| ARCN1 gene, Pulmonary Emphysema, Pneumonitis, Exacerbation | Altered Intercellular Communication | Azithromycin (AZM) reduces pulmonary inflammation and exacerbations in patients with COPD having emphysema. | 27486204 |
| Inflammation | Altered Intercellular Communication | These data suggest that the activation of the innate immune system and inflammation via TLR activation might have an essential role in the pathogenesis of PTDM in renal transplantation. | 27486667 |
| Pain Distress Question, Inflammation, Obesity | Altered Intercellular Communication | We examined whether the obesity and pain relationship is mediated by the high-sensitivity C-reactive protein (hsCRP), a nonspecific marker of systemic inflammation, and whether this relationship differs by sex. | 27486843 |
| Neoplasms, Primary malignant neoplasm, Obesity, prostatitis | Altered Intercellular Communication | The aim of this pilot study was to examine prostatic inflammation via tumor infiltrating lymphocytes and macrophages characterized by obesity and cancer severity. | 27487262 |
| Inflammation, Prostate carcinoma | Altered Intercellular Communication | However, these inflammation markers were associated with poor prostate cancer outcomes. | 27487262 |
| Inflammation, Atherosclerosis | Altered Intercellular Communication | In addition, the relationship between CRP, atherosclerosis, and inflammation remains controversial. | 27487299 |
| Inflammation, Lymphoid hyperplasia, Appendicitis, CTCAE | Altered Intercellular Communication | Acute inflammation was seen in 69 (48.9%) patients, lymphoid hyperplasia in 39 (27.7%) patients while parasitic appendicitis was seen in one (0.7%) patient. | 27487611 |
| Vascular Diseases, Inflammation, Fibrosis Assessment, Blood Clot, Hyperplasia | Altered Intercellular Communication | On the basis of a systematic clinicopathologic review of these 11 cases identified between 1982 and 2014, we describe a distinct mesenteric vasculopathy that involves both arteries and veins [mesenteric arteriovenous dysplasia/vasculopathy (MAVD/V)] and is characterized by (1) concentric/eccentric smooth muscle collarette around the tunica media of both the artery and the vein in >=2 foci, (2) varying degrees of intimal and medial hyperplasia and adventitial fibrosis, and (3) lack of inflammation or thrombi. | 27487739 |
| Chronic purulent otitis media, Otitis Media, Ear discharge | Altered Intercellular Communication | Chronic suppurative otitis media (CSOM) presents with purulent otorrhea (ear discharge), is characterized by chronic inflammation of the middle ear and mastoid cavity, and contributes to a significant disease burden worldwide. | 27487953 |
| Inflammation, Thrombosis, Disseminated Intravascular Coagulation, SLC25A10 gene | Altered Intercellular Communication | Neutrophils extracellular traps (NETs) have recently emerged as a new potential link between inflammation, immunity, and thrombosis and could play a key role in septic shock-induced disseminated intravascular coagulation (DIC) pathogenesis. | 27488091 |
| Inflammation, Tuberculosis | Altered Intercellular Communication | The commonest diagnosis seen was granulomatous inflammation consistent with tuberculosis (33.3%). | 27489015 |
| Rheumatoid Arthritis, Autonomic neuropathy, Chronic inflammation | Altered Intercellular Communication | Rheumatoid arthritis can cause cardiac autonomic neuropathy from chronic inflammation. | 27489064 |
| Degenerative polyarthritis, Inflammation, Degenerative disorder of cartilage | Altered Intercellular Communication | In particular, chronic inflammation may contribute to stress-induced senescence of chondrocytes and cartilage degeneration during OA progression. | 27490266 |
| Inflammation, Diabetes Mellitus, Non-Insulin-Dependent, atherosclerotic | Altered Intercellular Communication | Matrix metalloproteinases -2 and -9 (MMP-2 and MMP-9), which degrade collagen type IV of the vascular basement membrane, are responsible for vascular remodeling, inflammation, and atherosclerotic complications, including in type 2 diabetes (T2D). | 27490532 |
| Inflammation | Altered Intercellular Communication | However, the interaction between interviewer-rated acute stress and chronic family stress was significantly associated with adolescent inflammation markers (IL-6, IL-1ra). | 27490853 |
| Inflammation, selenium | Altered Intercellular Communication | Specifically, as chronic family stress increased, the association between acute stressor impact (interviewer-rated) and inflammation markers became more positive (IL-6 (B = .054, SE = .023, p = .022); IL-1ra (B = .030, SE = .014, p = .034)). | 27490853 |
| Inflammation | Altered Intercellular Communication | Among adolescents, interviewer-based ratings of acute stressor impact may allow for better prediction of health-relevant inflammation markers than adolescents' own ratings. | 27490853 |
| Inflammation | Altered Intercellular Communication | Subclinical inflammation is associated with development of increased glycaemia, insulin resistance and beta-cell function in non-diabetic individuals. | 27491375 |
| Inflammation, Hyperplasia | Altered Intercellular Communication | Mimickers of well-differentiated PC on mpMRI were inflammation, adenosis, HG-PIN and post-atrophic hyperplasia. | 27491874 |
| Sepsis, Communicable Diseases, Inflammation | Altered Intercellular Communication | The pathogen also needs to be considered in the challenging case of doubtful infection, where perhaps the only sign is inflammation, for a more accurate prediction of progression to either sepsis or healing. | 27492065 |
| Inflammation, Ulcerative Colitis | Altered Intercellular Communication | A long noncoding RNA signature for ulcerative colitis identifies IFNG-AS1 as an enhancer of inflammation. | 27492330 |
| Inflammation | Altered Intercellular Communication | Increased pulmonary vascular permeability and inflammation due to Ang-2 may play a role in the pathogenesis of AE-IIPs. | 27492510 |
| Inflammation, Heart failure | Altered Intercellular Communication | The chronic inflammation plays an important role in heart failure and complement components might be useful markers of the prognosis. | 27492980 |
| Inflammation, Diabetes Mellitus, Non-Insulin-Dependent | Altered Intercellular Communication | Emotion Dysregulation and Inflammation in African-American Women with Type 2 Diabetes. | 27493807 |
| Minimal Disseminated Disease, Inflammation, Post-Traumatic Stress Disorder, Unipolar Depression | Altered Intercellular Communication | C-reactive protein (CRP), a marker of systemic inflammation, has been associated with major depressive disorder (MDD) and posttraumatic stress disorder (PTSD). | 27493807 |
| Inflammation, Immune dysregulation, Diabetes Mellitus, Non-Insulin-Dependent | Altered Intercellular Communication | The objective of this study was to determine whether inflammation is associated with emotion dysregulation in women with type 2 diabetes mellitus (T2DM). | 27493807 |
| Inflammation | Altered Intercellular Communication | These findings suggest that emotion dysregulation may be an important risk factor for chronic inflammation beyond already known risk factors among women with T2DM, though a causal relationship cannot be determined from this study. | 27493807 |
| Inflammation, Coronary Artery Disease | Altered Intercellular Communication | Stress and inflammation are both important risk factors for coronary artery disease (CAD). | 27494070 |
| Inflammation, cervical cancer, cervical abnormality, Cervical Intraepithelial Neoplasia | Altered Intercellular Communication | These samples contained cervical abnormalities enriched with inflammation (n = 107), cervical intraepithelial neoplasia (CIN) I (n = 19), CINII-III (n = 9) and cervical cancer (n = 31). | 27494179 |
| Inflammation, Primary malignant neoplasm | Altered Intercellular Communication | Fucosylation is an important oligosaccharide modification associated with cancer and inflammation. | 27494861 |
| Inflammation, Cancer of Digestive System | Altered Intercellular Communication | The association between biliary tract inflammation and risk of digestive system cancers: A population-based cohort study. | 27495065 |
| Inflammation, Cancer of Digestive System | Altered Intercellular Communication | The relationship between biliary tract inflammation (BTI) and digestive system cancers is unclear. | 27495065 |
| Cholecystitis, Malignant neoplasm of stomach | Altered Intercellular Communication | The aHR of stomach cancer was also found to be increased (2.73; 95% CI: 1.28-5.81) in patients with gallbladder inflammation only. | 27495065 |
| Refractory anemias, Rheumatoid Arthritis, Damage | Altered Intercellular Communication | It is recognized that CC chemokine receptor 3 (CCR3) is associated with numerous inflammatory conditions and fibroblast-like synoviocyte (FLS) invasiveness correlates with articular damage in rheumatoid arthritis (RA). | 27495116 |
| Sepsis, Inflammation, Diabetes Mellitus | Altered Intercellular Communication | Diabetes is associated with chronic inflammation and activation of the vascular endothelium and the coagulation system, which in a more acute manner are also observed in sepsis. | 27495247 |
| Sepsis, Inflammation, Diabetes Mellitus | Altered Intercellular Communication | Plasma biomarker measurements revealed signs of systemic inflammation, and strong endothelial and coagulation activation in patients with sepsis, none of which were altered in those with diabetes. | 27495247 |
| Lupus Erythematosus | Altered Intercellular Communication | Chronic inflammatory conditions such as systemic lupus erythematosus considered as a recognize cause. | 27495304 |
| Mediastinitis | Altered Intercellular Communication | MIE was completed laparoscopically in 93 % of patients; two patients required conversion to an open procedure due to mediastinal inflammation following neoadjuvant chemoradiation. | 27495339 |
| Inflammation, Atherosclerosis | Altered Intercellular Communication | Increasing evidence points to the inflammatory character of atherosclerosis and several parameters of inflammation have been proposed as cerebrovascular risk markers. | 27498442 |
| Inflammation, Obstruction | Altered Intercellular Communication | Inflammation and obstruction of channel of sweat glands used to be thought to be the basis of this disease. | 27498534 |
| Dermatitis, Atopic, Inflammation | Altered Intercellular Communication | The patient was treated with Dr Michaels(r) (Eczitinex(r) and Itchinex(r)) ointment and herbal supplements and presented total resolution of the atopic eczema and underlying inflammation within 6 weeks. | 27498656 |
| Inflammation, Depression, CTCAE | Altered Intercellular Communication | Dietary factors and inflammation markers have been shown to play a role in the development of depression. | 27498949 |
| APP gene, Inflammation | Altered Intercellular Communication | It has been reported that development of AAA is associated with inflammation of the vascular wall; however, the mechanism of AAA rupture is not fully understood. | 27499372 |
| Inflammation | Altered Intercellular Communication | In the acute setting there is inflammation and an additional protein deficiency. | 27499393 |
| Communicable Diseases, Pneumonitis | Altered Intercellular Communication | Matrix metalloproteinases-9 (MMP-9) is considered significant in the pathogenesis of lung inflammation and infection. | 27499696 |
| Neoplasms, Ulcerative Colitis, Colitis | Altered Intercellular Communication | Effect of appendicectomy on colonic inflammation and neoplasia in experimental ulcerative colitis. | 27500367 |
| Inflammation, Lesion of liver, Necrosis, Fibrosis Assessment, Hepatotoxicity | Altered Intercellular Communication | Histopathological liver lesions were different depending on the onset of hepatotoxicity (acute or subacute): acinar zone 3 necrosis in case of acute symptoms, and portal tract inflammation with porto-central bridging and fibrosis in the delayed presentation. | 27500989 |
| Inflammation, physiopathological | Altered Intercellular Communication | The key metabolites and pathways may be possibly correlated with smooth muscle tone changes, increased collagen content, and inflammation, which have been identified as potential contributors to urinary dysfunction in humans and rodents. | 27502322 |
| Inflammation | Altered Intercellular Communication | IL-22 is an IL-10-family cytokine that regulates chronic inflammation. | 27502468 |
| Inflammation, Endothelial dysfunction, atherosclerotic | Altered Intercellular Communication | Here, we showed that adeno-associated viruses-GDF11 and recombinant GDF11 protein improve endothelial dysfunction, decrease endothelial apoptosis, and reduce inflammation, consequently decrease atherosclerotic plaques area in apolipoprotein E-/- mice. | 27502608 |
| Gastrointestinal Hemorrhage, Obstruction, Inflammation | Altered Intercellular Communication | Most often is asymptomatic but it may give a number of complications including gastrointestinal bleeding, obstruction and inflammation. | 27502885 |
| Refractory anemias, Inflammation, Lymphoma | Altered Intercellular Communication | However, since the excess risk of lymphoma in RA is related to the cumulative burden of inflammation, TNFi may conversely reduce the risk of lymphoma by decreasing the burden of inflammation. | 27502891 |
| Inflammation | Altered Intercellular Communication | Since Japanese dialysis patients are generally less inflamed than those in Western countries, inflammation may modify the association between serum ferritin and the adverse outcomes. | 27503345 |
| Inflammation, Depression, CTCAE, Sleep disturbances | Altered Intercellular Communication | An increasing body of evidence links the occurrence of sleep continuity disturbances with increased inflammation and both sleep disturbances and inflammation are associated with clinical depression. | 27503474 |
| Inflammation, Carcinogenesis | Altered Intercellular Communication | Chronic inflammation has been implicated in colorectal carcinogenesis. | 27504605 |
| Inflammatory abnormality of the eye, Epithelial | Altered Intercellular Communication | A successful clinical outcome, defined as a stable ocular surface without epithelial defects, a clear cornea without fibrovascular tissue invasion at the pupillary area, and no or mild ocular surface inflammation, was obtained in 15 of 20 eyes (75 %). | 27507558 |
| Inflammation, Pruritus | Altered Intercellular Communication | Air pollution-induced inflammation could occur in the skin and aggravate skin symptoms such as pruritus or impair epidermal barrier function. | 27507591 |
| Inflammation, Squamous cell carcinoma | Altered Intercellular Communication | White adipose tissue inflammation and cancer-specific survival in patients with squamous cell carcinoma of the oral tongue. | 27508351 |
| Inflammation, Squamous cell carcinoma | Altered Intercellular Communication | We investigated whether WAT inflammation in the tongue impacts survival in patients with squamous cell carcinoma (SCC) of the oral tongue. | 27508351 |
| Inflammation, Vascular Invasion Assessment, Neoplasms | Altered Intercellular Communication | Overall, 49 of 125 patients (39%) had tongue WAT inflammation, which was associated with higher body mass index, increased tumor thickness, and vascular invasion (P < .05). | 27508351 |
| Inflammation, Tissue Adhesions | Altered Intercellular Communication | In the LCBDE group, 4 (6.6%) patients were converted due to heavy inflammation and severe adhesions. | 27509535 |
| Inflammation | Altered Intercellular Communication | Neutrophil-lymphocyte ratio (NLR), an indicator of inflammation, has been lately demonstrated as a prognostic factor and an indicator of disease activity in various diseases. | 27510180 |
| Inflammation | Altered Intercellular Communication | * T1w-3D mVISTA visualized CWT/CCW as correlates of mural inflammation in LVV. | 27510630 |
| Trauma, Nervous System | Altered Intercellular Communication | It has been well established that inflammatory signaling pathways in ALS converge at NF-kB to promote neuronal damage. | 27512062 |
| Inflammation, Obesity, Abdominal, Hypertension, CTCAE | Altered Intercellular Communication | Vegetarian diet reduces the risk of hypertension independent of abdominal obesity and inflammation: a prospective study. | 27512965 |
| Inflammation, Hypertension, CTCAE, Obesity | Altered Intercellular Communication | A vegetarian diet may prevent elevation of blood pressures and lower the risk for hypertension through lower degrees of obesity, inflammation, and insulin resistance. | 27512965 |
| Inflammation, Obesity, Abdominal, Hypertension, CTCAE | Altered Intercellular Communication | Vegetarian diets may protect against hypertension beyond lower abdominal obesity, inflammation, and insulin resistance. | 27512965 |
| Inflammation, Metabolic Syndrome X | Altered Intercellular Communication | Elevated estimated arterial age is associated with metabolic syndrome and low-grade inflammation. | 27512974 |
| Cataract, Inflammation, Pain Distress Question | Altered Intercellular Communication | Topical nonsteroidal anti-inflammatory drugs (NSAIDs) are widely used for the prevention and treatment of inflammation and pain following cataract surgery. | 27513223 |
| Inflammation, ovarian neoplasm | Altered Intercellular Communication | Thus, excessive inflammation and oxidative stress caused an increase in DNA damage and enhanced Hcy content, leading to development of ovarian cancer. | 27513230 |
| Inflammation, Asthma, Exacerbation | Altered Intercellular Communication | This indicates that there is a value in measuring both FeNO and systemic eosinophilic inflammation in patients with asthma to identify individuals at high risk of exacerbations. | 27513280 |
| Inflammation, Asthma | Altered Intercellular Communication | FeNO and S-ECP are markers for inflammation in asthma, but are dependent on different inflammatory pathways and weakly correlated. | 27513280 |
| Airway structure, Asthma | Altered Intercellular Communication | Rhinovirus (RV) infection in asthma induces varying degrees of airway inflammation (e.g. | 27513438 |
| Pyroglyphidae, Pneumonitis | Altered Intercellular Communication | Tollip knockout and wild-type mice were challenged with house dust mite (HDM) and infected with RV1B to determine lung inflammation and antiviral response. | 27513438 |
| Pneumonitis | Altered Intercellular Communication | Upon HDM and RV1B, Tollip knockout (vs. wild-type) mice demonstrated higher levels of lung neutrophilic inflammation and viral load, but lower levels of antiviral gene expression. | 27513438 |
| Inflammation | Altered Intercellular Communication | The inadvertent application on the thin skin of the cheekbones led to a pronounced inflammation. | 27513756 |
| Inflammation, Conjunctivitis | Altered Intercellular Communication | With topical steroids followed by fusidic acid, both conjunctivitis and skin inflammation resolved within a few days. | 27513756 |
| Inflammation | Altered Intercellular Communication | BMI and fat distribution showed expected associations to inflammation biomarkers, but paradoxical relations between fat indices, and MetSyn components and biomarkers were seen. | 27513810 |
| Inflammation, Obesity | Altered Intercellular Communication | Effect of Obesity on Acute Ozone-Induced Changes in Airway Function, Reactivity, and Inflammation in Adult Females. | 27513854 |
| Inflammation, Obesity | Altered Intercellular Communication | Animal models suggest that obesity enhances ozone-induced airway reactivity and inflammation. | 27513854 |
| Airway structure, Obesity | Altered Intercellular Communication | However, acute ozone-induced airway reactivity to methacholine and airway inflammation did not differ by obesity at the exposure and exercise levels used. | 27513854 |
| Keratitis, Peroneal Neuropathies | Altered Intercellular Communication | We hypothesize that poor Ex-PRESS shunt positioning can act as a nidus for corneal inflammation, resulting in corneal neuropathy and lowering of the nociception threshold. | 27513904 |
| Inflammation | Altered Intercellular Communication | Knowledge of sepsis-related end-organ inflammation in vivo is limited. | 27514616 |
| palladium, Inflammation | Altered Intercellular Communication | An easy and inexpensive test of an NLR greater than 3 could be used as a measure of inflammation instead of HSCRP in both PD and hemodialysis patients. | 27514767 |
| Kidney Failure, Chronic, Inflammation, Electrocardiogram: left ventricle hypertrophy (finding) | Altered Intercellular Communication | Inflammation, Left Ventricular Hypertrophy, and Mortality in End-stage Renal Disease. | 27514769 |
| Inflammation, Ventricular hypertrophy, Cardiovascular system | Altered Intercellular Communication | Inflammation, pulse pressure, and left ventricular hypertrophy are interrelated and all contribute to mortality and cardiovascular death risk among dialysis patients. | 27514769 |
| Inflammation, "Alzheimers Disease | Altered Intercellular Communication | Neuroprotective effects of apigenin against inflammation, neuronal excitability and apoptosis in an induced pluripotent stem cell model of Alzheimer's disease. | 27514990 |
| Refractory anemias, Pain Distress Question, Inflammation | Altered Intercellular Communication | Pain persists in people with treated RA, even in those for whom inflammation responds to treatment. | 27515300 |
| Communicable Diseases, Inflammation, septic, Granulomatous inflammation | Altered Intercellular Communication | Granulomatous inflammations are a particular type of chronic septic or aseptic inflammation, in which infectious or non-infectious agents are difficult to eliminate by the immune system. | 27516029 |
| Inflammation, Granulomatous, Granuloma | Altered Intercellular Communication | At cutaneous level, this pattern of granulomatous reaction is characterized by a chronic inflammation with formation of granulomas consisting of a variable number of histiocytes, multinucleated giant cells and lymphocytes. | 27516029 |
| Granulomatous dermatitis, Inflammation, Neoplasms | Altered Intercellular Communication | Granulomatous dermatoses should be differentiated from other primary or secondary lesions affecting the skin such as inflammation or tumors. | 27516029 |
| Communicable Diseases, Inflammation, septic, Granulomatous inflammation | Altered Intercellular Communication | Granulomatous inflammations are a particular type of chronic septic or aseptic inflammation, in which infectious or non-infectious agents are difficult to eliminate by the immune system. | 27516029 |
| Arteritis | Altered Intercellular Communication | Blood supply blockage can occur with or without arterial inflammation. | 27516038 |
| Airway structure, Asthma, Obstruction | Altered Intercellular Communication | Computer-aided lung sound analysis (LSA) has been reported to be useful for evaluating airway inflammation and obstruction in asthma patients. | 27516132 |
| Chronic kidney disease mineral and bone disorder, Inflammation | Altered Intercellular Communication | Metabolic and inflammation biomarkers potentially linked to CKD-MBD were also analysed. | 27519971 |
| bleomycin/cisplatin/vinblastine protocol, Inflammation, SLC25A20 gene, Cyclophosphamide/Vincristine/Dacarbazine Regimen, Diabetes Mellitus | Altered Intercellular Communication | Low VBD was independently associated with higher CAC score (>100 AUs) after adjustment for age, gender, diabetes, CVD, inflammation and cohorts. | 27519971 |
| bleomycin/cisplatin/vinblastine protocol, Inflammation, Cyclophosphamide/Vincristine/Dacarbazine Regimen, Diabetes Mellitus | Altered Intercellular Communication | In Cox proportional hazards analysis, low VBD was independently associated with all-cause mortality after adjustment for age, gender, diabetes, CVD, inflammation and subjective global assessment (SGA). | 27519971 |
| Malignant neoplasm of larynx, Palsy | Altered Intercellular Communication | The participants (N = 80 larynx cancer, N = 32 recurrent palsy, N = 23 dysfunctional, N = 75 degenerative/inflammation, N = 19 various) were included consecutively at the laryngology clinic at Haukeland University Hospital. | 27520510 |
| Inflammation, MYELODYSPLASTIC SYNDROME, Miller Dieker syndrome | Altered Intercellular Communication | Inflammation has an essential role in the pathogenesis of myelodysplastic syndromes (MDS). | 27521329 |
| Inflammation, Fibrosis Assessment | Altered Intercellular Communication | We measured HTGC, body composition, circulating markers of inflammation, fibrosis, and glucose tolerance at baseline and at 12 weeks. | 27521509 |
| Inflammation, Maternal infection | Altered Intercellular Communication | Our objective was to identify risk factors associated with maternal infections and placental inflammation in pregnant adolescents attending an urban adolescent maternity clinic. | 27521899 |
| Inflammation, Infection | Altered Intercellular Communication | The prevalence of maternal infections and placental inflammation was determined and potential risk factors were identified. | 27521899 |
| Presenile dementia, Inflammation | Altered Intercellular Communication | Vascular risk factors, including inflammation, may contribute to dementia development. | 27522059 |
| Inflammation | Altered Intercellular Communication | The combined inflammation z-score was significantly associated with memory and psychomotor speed (p < .01). | 27522059 |
| Inflammation | Altered Intercellular Communication | Our results suggest that total inflammation is associated with memory and psychomotor speed. | 27522059 |
| Inflammation, vascular inflammations | Altered Intercellular Communication | In particular, systemic inflammation, vascular inflammation, and altered endothelial function may play roles in domain-specific cognitive decline of nondemented individuals. | 27522059 |
| Inflammation | Altered Intercellular Communication | Thus, induction of the immunoproteasome was identified as a pathomechanism underlying inflammation in IIMs. | 27522114 |
| Inflammation, Fibrosis Assessment | Altered Intercellular Communication | The mean tissue concentrations of all 10 metals and non-metal were significantly lower in NP patients than in healthy controls (P < 0.05).TEM and SEM revealed changes in the mucosal ultrastructure in NP with progressive fibrosis, devascularisation, and inflammation. | 27522207 |
| Inflammation, Atherosclerosis | Altered Intercellular Communication | The objective of the study was to determine if the association between airflow obstruction and markers of atherosclerosis is mediated by systemic inflammation. | 27522264 |
| Inflammation, Calcification of the aorta, Leukocytes | Altered Intercellular Communication | After adjusting for population characteristics, Framingham cardiovascular risk factors and markers of systemic inflammation (WBC and CRP), there was a significantly increased aortic arch and distal aorta calcification and higher CIMT measurement in individuals with airflow obstruction compared to individuals without airflow obstruction. | 27522264 |
| Inflammation, Calcification of the aorta, Leukocytes | Altered Intercellular Communication | After adjusting for population characteristics, Framingham cardiovascular risk factors and markers of systemic inflammation (WBC and CRP), there was a significantly increased aortic arch and distal aorta calcification and higher CIMT measurement in individuals with airflow obstruction compared to individuals without airflow obstruction. | 27522264 |
| Inflammation, Leukocytes, Atherosclerosis | Altered Intercellular Communication | Systemic inflammation (WBC and CRP) does not appear to mediate the association between airflow limitation and atherosclerosis. | 27522264 |
| Inflammation, Leukocytes, Atherosclerosis | Altered Intercellular Communication | Only airflow limitation and not systemic inflammation (WBC and CRP) appears to be an independent predictor of atherosclerosis. | 27522264 |
| Diabetic Nephropathy, Inflammation, Fibrosis Assessment | Altered Intercellular Communication | Serum microRNA-217 may be involved in the development of diabetic kidney disease by promoting chronic inflammation, renal fibrosis, and angiogenesis. | 27522360 |
| Inflammation, Rheumatoid Arthritis | Altered Intercellular Communication | Calcium supplementation and inflammation increase mortality in rheumatoid arthritis: A 15-year cohort study in 609 patients from the Oslo Rheumatoid Arthritis Register. | 27522465 |
| Inflammation, Hemorrhage | Altered Intercellular Communication | Massive amyloid deposits were present in the vessels, and collapsed internal elastic laminae with lymphocyte infiltration were observed at the site of amyloid deposits in the bronchial artery, suggesting that deposits with inflammation might cause the collapse of the bronchial artery and lead to hemorrhage. | 27522614 |
| Inflammation, Amyloidosis, Heart failure | Altered Intercellular Communication | In amyloidosis patients who suffer heart failure, there is the potential for vascular collapse caused by the accumulation of amyloid deposits with inflammation. | 27522614 |
| Inflammation, Metabolic Diseases, pathologic cytolysis, Arthritis, Cholestasis | Altered Intercellular Communication | High activity of hepatocytes cytolysis, cholestasis, inflammation, metabolic disorders let us considerpsoriatic arthritis as a severe clinical stage psoriatic disease when the hepatobiliary system, in turn, is one of the main target organs in systemic psoriatic process. | 27522710 |
| Inflammation, Neoplasms | Altered Intercellular Communication | The mRNA expression of specific biomarkers (SGLT1, SGLT5, GIP, GLP, LAT1, LAT2, and NPC1L1) in the mucosa was compared among three patient groups: Inflammation, Tumor, and Control. | 27522989 |
| Inflammation | Altered Intercellular Communication | Premenopausal women were at an increased risk of lobular inflammation, hepatocyte ballooning, and Mallory-Denk bodies than men and also at an increased risk of lobular inflammation and Mallory-Denk bodies than postmenopausal women (P < .01). | 27523635 |
| Ischemia, Inflammation | Altered Intercellular Communication | Post-cardiac arrest syndrome (PCAS) is characterized by whole-body ischemia triggering systemic inflammation and damage of the endothelium. | 27523954 |
| Cardiac Arrest, Inflammation, Corneal Endothelial Cell Loss | Altered Intercellular Communication | This study investigated the relationship between systemic inflammation, endothelial damage and severity of PCAS and the association between endothelial damage and outcome after out-of-hospital cardiac arrest (OHCA). | 27523954 |
| Inflammation, Comatose, SLITRK1 wt Allele | Altered Intercellular Communication | In comatose survivors after OHCA treated with TTM, systemic inflammation was associated with endothelial activation and endothelial damage. | 27523954 |
| ARCN1 gene, Inflammation | Altered Intercellular Communication | Certain individual circulating cytokines (particularly TNFa and IL-1b) were significantly elevated in concentration in the serum of particular COPD patients (and some current/ex-smokers without COPD) and may serve as markers of particularly significant systemic inflammation. | 27524865 |
| Facilitation | Altered Intercellular Communication | Unlike VD, the hyperfacilitation found at baseline in VCI-ND patients suggests enhanced glutamatergic neurotransmission that might contribute to the preservation of cognitive functioning. | 27525127 |
| Granulomatous inflammation | Altered Intercellular Communication | and usually presents as a chronic, suppurative and granulomatous inflammation with a propensity to mimic malignant conditions. | 27526941 |
| Dental caries, Pulpitis | Altered Intercellular Communication | Moreover, complete removal of carious dentin in deep carious lesions often leads to pulp exposure and root canal treatment, despite the absence of irreversible pulp inflammation. | 27527342 |
| ovarian neoplasm, Inflammation, Malignant Neoplasms, Neoplasms | Altered Intercellular Communication | Ovarian cancer is a highly complex heterogeneous malignancy in respect of tumor anatomy, tumor microenvironment including pro-/antitumor immunity and inflammation; still, it is generally treated as single disease. | 27527602 |
| Inflammation, Atherosclerosis, Marfan Syndrome, Traumatic injury, Hypertension, CTCAE | Altered Intercellular Communication | It is most commonly associated with trauma or surgery, less commonly with atherosclerosis, inflammation, hypertension or Marfan's syndrome. | 27527829 |
| Inflammation | Altered Intercellular Communication | Critically, hormesis could improve mitochondrial quantum efficiency, improving the ATP/ROS ratio, whereas inflammation, which is tightly associated with the aging process, might do the opposite. | 27528758 |
| Inflammation, Uterine Cervicitis, Mucous retention cyst of cervix uteri | Altered Intercellular Communication | According to our study, among misdiagnosed patients, nabothian cysts and cervicitis were the most common histological findings; FDPs were more often symptomatic (p < 0.001) and coexisted more frequently with inflammation or ulceration (p < 0.001). | 27529156 |
| Inflammation, Ulceration, CTCAE, Ulcerative Colitis | Altered Intercellular Communication | Colonoscopy revealed inflammation and ulceration with biopsy consistent with ulcerative colitis (UC). | 27530224 |
| Anti-Neutrophil Cytoplasmic Antibody-Associated Vasculitis, AAVS1 gene | Altered Intercellular Communication | In recent literature, antineutrophil cytoplasmic autoantibodies (ANCA) positivity has been reported in various inflammatory conditions other than ANCA-associated vasculitis (AAV). | 27530224 |
| Inflammation, Mitochondria | Altered Intercellular Communication | Inflammation in adult women with a history of child maltreatment: The involvement of mitochondrial alterations and oxidative stress. | 27530300 |
| Inflammation | Altered Intercellular Communication | The experience of maltreatment during childhood is associated with chronic low-grade inflammation in adulthood. | 27530300 |
| Inflammation | Altered Intercellular Communication | To this end, we hypothesized that alterations in immune cell mitochondrial functioning and oxidative stress might be at the interface between the association of maltreatment experiences during childhood and inflammation. | 27530300 |
| Inflammation, Thrombosis, ASAH1 gene, Anemia | Altered Intercellular Communication | Further evaluation of this association is warranted as it may shed light on mechanistic relations between anemia, inflammation, and thrombosis after aSAH. | 27530692 |
| Inflammation, Primary malignant neoplasm | Altered Intercellular Communication | Chronic adventitial inflammation, vasa vasorum expansion, and 5-lipoxygenase up-regulation in irradiated arteries from cancer survivors. | 27530979 |
| Inflammation, Primary malignant neoplasm | Altered Intercellular Communication | These results point to targeting the 5-LO/leukotriene pathway as a therapeutic adjunct to prevent late adverse vascular effects of radiotherapy.-Halle, M., Christersdottir, T., Back, M. Chronic adventitial inflammation, vasa vasorum expansion, and 5-lipoxygenase up-regulation in irradiated arteries from cancer survivors. | 27530979 |
| Inflammation, Takayasu Arteritis | Altered Intercellular Communication | These processes may influence arterial inflammation and remodelling in Takayasu arteritis (TA). | 27531191 |
| Inflammation, Hypertensive (finding) | Altered Intercellular Communication | Markers of systemic or local inflammation correlated with higher CgA-FRs and VS-1 in normotensive patients and with higher CgA439 in hypertensive patients. | 27531191 |
| Inflammation, Obesity | Altered Intercellular Communication | The n-3 polyunsaturated fatty acids (PUFAs) eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA) may reduce low-grade inflammation associated with obesity. | 27531277 |
| Inflammation | Altered Intercellular Communication | Administration of anti-tuberculosis chemotherapy caused: (a) diminution of inflammation, (b) diminution of the size of local fusiform injury, and (c) clinical improvement. | 27531321 |
| Inflammation, Bronchiolitis | Altered Intercellular Communication | cDCs accumulate in the lower airways during RSV bronchiolitis, are activated systemically and may, through activation of T cells, NK T cells and NK cells, contribute to RSV-induced inflammation and disease. | 27531529 |
| Swelling | Altered Intercellular Communication | Differences of weight between right and left ears were measured by ear swelling method and anti-inflammation experiment. | 27534086 |
| Viremia, Hepatitis | Altered Intercellular Communication | All Bama miniature swine that were infected with HEV genotypes 3 and 4 exhibited significant HEV viremia, shedding, anti-HEV antibody responses and partial liver inflammation. | 27534702 |
| Mucous Membrane, Inflammation | Altered Intercellular Communication | Most studies show a relatively high prevalence of mucosal atrophy and inflammation in treated patients, a finding which have led to a concept of non-responsive CD. | 27534885 |
| Inflammation, Cardiovascular morbidity | Altered Intercellular Communication | Heart rate (HR), heart rate variability (HRV), and inflammation are all associated with cardiovascular morbidity and mortality. | 27534940 |
| Inflammation, Necrosis | Altered Intercellular Communication | High-mobility group box 1 (HMGB1) is a nuclear protein that triggers inflammation when released from activated immune or necrotic cells and drives the pathogenesis of various infectious agents. | 27535058 |
| Airway structure, Inflammatory disorder | Altered Intercellular Communication | Although HMGB1 has been implicated in many inflammatory diseases, its role in RSV-induced airway inflammation has not been investigated. | 27535058 |
| Airway structure | Altered Intercellular Communication | HMGB1 is a ubiquitous redox-sensitive multifunctional protein that serves as both a DNA regulatory protein and an extracellular cytokine signaling molecule that promotes airway inflammation as a damage-associated molecular pattern. | 27535058 |
| Inflammation, Antiphospholipid Syndrome, atherosclerotic | Altered Intercellular Communication | NTPV-associated aPL might be distinct from classic antiphospholipid syndrome and should be considered in aPL-positive patients who present with vascular occlusions of medium-sized vessels in the absence of atherosclerotic risk factors and systemic or local inflammation. | 27535710 |
| Inflammatory Bowel Diseases, Gastrointestinal inflammation | Altered Intercellular Communication | Our aim was to assess mucosal miRNA expression in IBD and the correlation with intestinal inflammation. | 27536783 |
| Inflammatory abnormality of the eye | Altered Intercellular Communication | New Zealand has a multicultural population with a wide spectrum of ocular inflammation that varies with ethnicity and age. | 27537334 |
| Inflammation, Pulmonary Hypertension | Altered Intercellular Communication | The granulomatous inflammation found in the histology supports a sarcoid-like reaction due to pulmonary hypertension in the context of the BMPR2 mutation. | 27537724 |
| Inflammation, Brain Injuries, Cerebral Hemorrhage | Altered Intercellular Communication | Inflammation is involved in pathophysiological mechanisms underlying secondary brain injury after intracerebral hemorrhage. | 27538613 |
| Inflammation, Cerebral Hemorrhage | Altered Intercellular Communication | This study was designed to investigate whether plasma galectin-3 levels are related to the inflammation, severity and prognosis following intracerebral hemorrhage. | 27538613 |
| Inflammation, Brain hemorrhage, Cerebral Hemorrhage | Altered Intercellular Communication | Elevated plasma galectin-3 levels are strongly associated with the inflammation, severity and poor prognosis after intracerebral hemorrhage, indicating galectin-3, involved in brain inflammation, might have the potential to be a prognostic biomarker for hemorrhagic stroke. | 27538613 |
| Inflammation | Altered Intercellular Communication | By clarifying joint inflammation in an IA cohort with overall low ESR, ultrasonography of physician-selected joints can improve clinical assessment, resulting in treatment modification. | 27538766 |
| Diffuse Large B-Cell Lymphoma, Chronic inflammation | Altered Intercellular Communication | We report an 80 year old female patient who developed a DLBCL with chronic inflammation in association to a metallic implant in the left knee. | 27539226 |
| Diffuse Large B-Cell Lymphoma, Chronic inflammation | Altered Intercellular Communication | This report challenges the concept of DLBCL associated with chronic inflammation and raises the question of other pathogenetic factors involved in the pathogenesis of this rare disease. | 27539226 |
| Pain Distress Question | Altered Intercellular Communication | Chronic elevation of the pain neurotransmitter substance P (SP) sensitizes pain nociceptors. | 27539682 |
| Unknown (origin) (qualifier value), Inflammation, Pain Distress Question | Altered Intercellular Communication | Hence, the burning sign may be associated with pain and inflammation in idiopathic FS. | 27539943 |
| Inflammation, Asthma | Altered Intercellular Communication | Patients with both systemic inflammation and comorbidities showed poorest outcome of asthma. | 27540019 |
| Renal Insufficiency, Inflammation, Choline Dehydrogenase, Mitochondrial, myocardial injury | Altered Intercellular Communication | Galectin-3 does not independently predict recurrent cardiovascular events in patients with established CHD after adjustment for markers of hemodynamic stress, myocardial injury, inflammation, and renal dysfunction. | 27540030 |
| Inflammation, Diabetes Mellitus, Non-Insulin-Dependent | Altered Intercellular Communication | Our findings indicate that mechanisms related to inflammation, including macrophage activation and adipocyte metabolism, may play a role in changes in glucose homeostasis in individuals at high risk of type 2 diabetes mellitus. | 27541014 |
| Inflammation, Astigmatism | Altered Intercellular Communication | The gold weight was removed in four patients (10.5%), due to chronic inflammation in three and due to mild astigmatism in one. | 27541938 |
| Inflammation, Traumatic injury | Altered Intercellular Communication | Marjolin ulcers (MU) classically present as an aggressive SCC in area of chronic inflammation, which has been previously correlated to constant pressure, repetitive trauma, or non-healing wounds in other areas of the body. | 27541940 |
| Colitis | Altered Intercellular Communication | Finally, the colonic cytokine levels and disease scores of the AdTr model indicated reduced levels of colonic inflammation in liraglutide-dosed animals. | 27542128 |
| Inflammation | Altered Intercellular Communication | Non-infectious uveitis is a potentially sight-threatening ocular disorder caused by chronic inflammation and its complications. | 27542302 |
| Inflammation, Hodgkin Disease | Altered Intercellular Communication | The presence of CD30-expressing Hodgkin-like cells with a background of inflammation and eosinophils in a young adolescent is usually diagnostic of classical Hodgkin lymphoma. | 27543511 |
| PROS1 gene, Inflammation, Psoriasis, Tumor necrosis, Arthritis, Psoriatic | Altered Intercellular Communication | Cytokines such as tumour necrosis factor (TNF)-a, interleukin (IL)-12, interferon (IFN)-g, IL-23 and, more recently, IL-9, have been implicated in the initiation/maintenance of inflammation in psoriasis and psoriatic arthritis (PsA). | 27543964 |
| Inflammation, Atherosclerosis | Altered Intercellular Communication | Inflammation plays an important role on every stage of atherosclerosis. | 27544604 |
| nervous system disorder, Inflammation, Autonomic nervous system | Altered Intercellular Communication | CONCLUSIONS Chronic inflammation in the course of CD may lead to autonomic nervous system impairment and development of neurologic disorders. | 27545437 |
| Heart failure | Altered Intercellular Communication | Parathyroid hormone is associated with heart failure with preserved ejection fraction. | 27546695 |
| Inflammation, Vertebrobasilar Insufficiency, Atherosclerosis | Altered Intercellular Communication | Vertebrobasilar insufficiency and gamma-glutamyltransferase: An emerging relationship demonstrating inflammation and atherosclerosis. | 27546696 |
| Inflammation, Vertebrobasilar Insufficiency, eVLP CMV gB-pp65 Plus GM-CSF VBI-1901, Atherosclerosis | Altered Intercellular Communication | Vertebrobasilar insufficiency (VBI) is a pathology arising from the reduction in flow rate of vertebral arteries and mainly caused by inflammation and atherosclerosis. | 27546696 |
| Inflammation, Atherosclerosis | Altered Intercellular Communication | Gamma-glutamyltransferase (GGT) is a marker which has been recently recognized as a marker of inflammation and atherosclerosis. | 27546696 |
| Atherosclerosis | Altered Intercellular Communication | In addition, higher GGT level was an independent risk factor for the presence of vertebrobasilar system inflammation and atherosclerosis (Tab. | 27546696 |
| Degenerative polyarthritis, Inflammation | Altered Intercellular Communication | Systemic inflammation and painful joint burden in osteoarthritis: a matter of sex? | 27546883 |
| Degenerative polyarthritis, Inflammation | Altered Intercellular Communication | There may be a dose-response association between painful joint burden in OA and systemic inflammation, and it appears the association is sex-specific, which may in part explain inconsistent findings in the literature. | 27546883 |
| Degenerative polyarthritis, Inflammation | Altered Intercellular Communication | Our results underline the importance of showing sex-specific associations in OA, especially when studying the influence of inflammation. | 27546883 |
| Nonalcoholic Steatohepatitis, Inflammation, Non-alcoholic Fatty Liver Disease, Fatty Liver Disease | Altered Intercellular Communication | The progression of non-alcoholic fatty liver disease (NAFLD) to non-alcoholic steatohepatitis (NASH) is associated with inflammation. | 27548138 |
| Inflammation, Fibrosis Assessment, Fatty Liver Disease | Altered Intercellular Communication | In male patients weak positive correlations with inflammation, fibrosis and NASH score were identified. | 27548138 |
| Inflammation, Aortic valve calcification | Altered Intercellular Communication | Inflammation is an important factor in the pathogenesis of calcific aortic stenosis (AS). | 27548384 |
| Sepsis, Inflammation | Altered Intercellular Communication | ANG1 is a Tie2 agonist that promotes vascular stabilization in inflammation and sepsis, whereas ANG2 is a context-dependent Tie2 agonist or antagonist. | 27548530 |
| Inflammation, Periodontitis | Altered Intercellular Communication | However, many of these potential OSCC salivary biomarkers are also involved in chronic inflammation, and whether the levels of these biomarkers could be affected by the presence of chronic periodontitis was not known. | 27549383 |
| Inflammation, pyloric region | Altered Intercellular Communication | Because of the corrosive effect, he developed severe inflammation of the upper gastro intestinal tract with narrowing of esophagus and pyloric region, requiring feeding jejunostomy. | 27549430 |
| Gestational Diabetes, Inflammation | Altered Intercellular Communication | Elevated GCF IL-10 levels may be a consequence of higher levels of inflammation as indicated by higher PI and BOP in the GDM group. | 27552375 |
| Inflammation, Albuminuria, Diabetes Mellitus, Non-Insulin-Dependent | Altered Intercellular Communication | Inflammation plays an important role in albuminuria in type 2 diabetes mellitus (T2DM). | 27552538 |
| Inflammation | Altered Intercellular Communication | Aging, not age-associated inflammation, determines blood pressure and endothelial responses to acute inflammation. | 27552645 |
| Inflammation | Altered Intercellular Communication | Aging is characterized by a state of chronic, low-grade inflammation that impairs vascular function. | 27552645 |
| Inflammation | Altered Intercellular Communication | Acute inflammation causes additional decrements in vascular function, but these responses are not uniform in older compared with younger adults. | 27552645 |
| Inflammation | Altered Intercellular Communication | We hypothesized age-related differences in the vascular responses to acute inflammation, but that older adults with low baseline inflammation would respond similarly to younger adults. | 27552645 |
| Inflammation | Altered Intercellular Communication | Aging, not age-related chronic, low-grade inflammation, determines the vascular responses to acute inflammation. | 27552645 |
| Communicable Diseases, Inflammation, Lung diseases, Lung Injury | Altered Intercellular Communication | Treatment of lung disease to reduce the impact of infection, inflammation and subsequent lung injury is therefore of major importance. | 27552791 |
| Neoplasms | Altered Intercellular Communication | The Glasgow prognostic score (GPS) is an inflammation-based score based on albuminemia and C-reactive protein concentration proved to be associated with cancer-specific survival in several neoplasms. | 27553499 |
| Inflammation | Altered Intercellular Communication | Weight discrimination was associated with lipid/metabolic dysregulation (1.56; 95 % CI 1.02, 2.40), glucose metabolism (1.99; 95 % CI 1.34, 2.95), and inflammation (1.76; 95 % CI 1.22, 2.54), but no other systems. | 27553775 |
| Inflammation, Arthritis, Gouty, Synovial Neoplasm | Altered Intercellular Communication | Pathology +- microbiology findings for these 107 conclusive biopsies comprised synovial tumour (n = 30, 28 %), synovial infection (n = 18, 17 %), synovial inflammation (n = 45, 42 %), including gouty arthritis (n = 3), and no abnormality (n = 14, 13 %). | 27553941 |
| atherosclerotic | Altered Intercellular Communication | This possible contribution of immune mediators to an atherosclerotic process probably relates to the inflammaging process. | 27554076 |
| Airway structure, Steroid-resistant nephrotic syndrome | Altered Intercellular Communication | Our findings reveal age differences in LT and Wnt pathways during airway inflammation and identify a steroid-resistant cascade of Wnt5a, Tgm2, and LTs, which might represent a therapeutic target for airway inflammation and remodeling. | 27554815 |
| Inflammation | Altered Intercellular Communication | We sought to characterize molecularly cutaneous inflammation and its correlation with clinical and barrier characteristics. | 27554821 |
| Inflammation, Ichthyoses, Dehydration | Altered Intercellular Communication | These markers also significantly correlated with transepidermal water loss, suggesting a link between the barrier defect and inflammation in patients with ichthyosis. | 27554821 |
| Inflammation, Periodontal Diseases | Altered Intercellular Communication | Periodontal disease is associated with increased systemic inflammation in stable cardiovascular patients. | 27556206 |
| Inflammation | Altered Intercellular Communication | The pharmacological activities of many Punica granatum L. components suggest a wide range of clinical applications for the prevention and treatment of diseases where chronic inflammation is believed to play an essential etiologic role. | 27556440 |
| Inflammation, Malignant Neoplasms | Altered Intercellular Communication | Hematological biomarkers of inflammation such as the neutrophil-to-lymphocytic rate have been reported as predictors of survival in a variety of cancers. | 27556669 |
| Inflammation | Altered Intercellular Communication | AI correlates with CLE markers of acute and chronic inflammation. | 27557471 |
| Inflammation | Altered Intercellular Communication | Normal level of apoptosis and DNase I activity simultaneously reduce the level of acute inflammation in CLE. | 27557471 |
| Squamous cell carcinoma of esophagus | Altered Intercellular Communication | A novel inflammation-based prognostic score for patients with esophageal squamous cell carcinoma: the c-reactive protein/prognostic nutritional index ratio. | 27557504 |
| Inflammation, Primary malignant neoplasm | Altered Intercellular Communication | Inflammation plays a critical role in cancer prognosis. | 27557504 |
| Squamous cell carcinoma of esophagus | Altered Intercellular Communication | In the current study, we proposed a novel inflammation-based prognostic score, named c-reactive protein/prognostic nutritional index ratio (CRP/PNI ratio), for predicting the prognosis for patients with resectable esophageal squamous cell carcinoma (ESCC). | 27557504 |
| Inflammation | Altered Intercellular Communication | Both adipose tissue and monocyte/macrophages contribute to the increased inflammation in MetS. | 27557909 |
| Necrotizing granulomatous inflammation, Squamous cell carcinoma | Altered Intercellular Communication | Initially this was thought to be an invasive squamous cell carcinoma but a biopsy showed histological features consistent with necrotizing granulomatous inflammation. | 27558192 |
| Inflammatory Bowel Diseases, Crohn Disease, Inflammation, Ulcerative Colitis | Altered Intercellular Communication | Inflammatory bowel disease (IBD), manifesting as Crohn's disease (CD) and ulcerative colitis (UC), is characterized by recurring episodes of inflammation in gastrointestinal tract, in which aberrant production of regulatory cytokine interleukin-10 (IL-10) presumably plays important role. | 27558476 |
| Pain Distress Question, Inflammation | Altered Intercellular Communication | There is limited evidence that ginger powder consumption can relieve pain and inflammation due to specific anti-inflammatory phytochemical constitutents. | 27559855 |
| Sarcoma, Inflammation | Altered Intercellular Communication | Moreover, it provides further indications regarding the potential association between foreign body reaction on the basis of chronic inflammation and sarcoma development. | 27559958 |
| Inflammation, Osteoporotic Fractures | Altered Intercellular Communication | There is still debate on whether high uric acid increases bone mineral density (BMD) against osteoporotic fracture or bone resorption caused by gout inflammation. | 27559970 |
| Inflammation, Asthma | Altered Intercellular Communication | Peroxisome proliferator-activated receptor gamma (PPAR-g) is a nuclear receptor that modulates inflammation in models of asthma. | 27560168 |
| Inflammation, Sample Size Calculation | Altered Intercellular Communication | CD8 + T cells may significantly contribute to inflammation in SSc. | 27560622 |
| Inflammation | Altered Intercellular Communication | In obese individuals, visceral adipose tissue (VAT) is the seat of chronic low-grade inflammation (metaflammation), but the mechanistic link between increased adiposity and metaflammation largely remains unclear. | 27561727 |
| Inflammation, Obesity | Altered Intercellular Communication | Thus, this study reveals a pathway that drives adipose tissue inflammation and consequent IR in obesity. | 27561727 |
| Inflammation, Pain Distress Question | Altered Intercellular Communication | Inflammation and pain were determined using serum high sensitivity C-reactive protein (hs-CRP) and a visual analogue scale (VAS), respectively. | 27561790 |
| Refractory anemias, Rheumatoid Arthritis | Altered Intercellular Communication | Rheumatoid arthritis (RA) is a chronic inflammatory condition associated with an increased risk of cardiovascular mortality. | 27561790 |
| Refractory anemias, Rheumatoid Arthritis | Altered Intercellular Communication | Rheumatoid arthritis (RA) is a chronic inflammatory condition associated with increased cardiovascular morbidity/mortality and an incompletely understood pathophysiology. | 27561790 |
| Dermatomyositis, Paresis, Autoimmune myopathy, Myositis | Altered Intercellular Communication | Dermatomyositis is an autoimmune myopathy characterized by proximal muscle weakness, muscle inflammation, and typical skin findings. | 27561848 |
| ARCN1 gene, Inflammation | Altered Intercellular Communication | Reducing ADAM17 and EGFR activity could therefore be a therapeutic approach for the tissue remodeling and inflammation observed in COPD. | 27561911 |
| Inflammation, Fibrosis Assessment | Altered Intercellular Communication | The role of sphingosine 1-phosphate (S1P) in liver fibrosis or inflammation was not fully examined in human. | 27562371 |
| Inflammation, Fibrosis Assessment | Altered Intercellular Communication | In conclusion, S1P may be actively generated, transported to outside the cells, and bind to its specific receptor in human liver to play a role in fibrosis or inflammation. | 27562371 |
| Inflammation, Depression, CTCAE | Altered Intercellular Communication | Association of inflammation with specific symptoms of depression in a general population of older people: The English Longitudinal Study of Ageing. | 27562420 |
| Inflammation, Malignant Neoplasms | Altered Intercellular Communication | In this context, inflammation has an important role in the development and progression of many malignancies. | 27564278 |
| Inflammation, Nasopharyngeal carcinoma | Altered Intercellular Communication | Increased Risk of Nasopharyngeal Carcinoma with Increasing Levels of Diet-Associated Inflammation in an Italian Case-Control Study. | 27564524 |
| Inflammation, Nasopharyngeal carcinoma | Altered Intercellular Communication | Components of diet can modulate inflammation and therefore may have an important role in the development of nasopharyngeal carcinoma (NPC). | 27564524 |
| Injury of integument | Altered Intercellular Communication | Furthermore, we show that on acute skin injury in both human and murine settings, this transition occurs quickly, consistent with a response to inflammatory signaling. | 27565038 |
| Pancreatitis | Altered Intercellular Communication | A follow-up MRCP revealed a swollen pancreas and pancreatic inflammation. | 27565931 |
| Inflammation, Primary malignant neoplasm | Altered Intercellular Communication | Connections exist between inflammation and cancer, for example with regard to disease progression and prognosis. | 27566075 |
| Inflammation | Altered Intercellular Communication | Nitric oxide (NO) pathway plays a major role in the development and advancement of inflammation. | 27566088 |
| Inflammation, Neoplasms | Altered Intercellular Communication | Deep study of RUNX3 inflammation signaling could help in understanding inflammation and immune activation in the tumor microenvironment. | 27566570 |
| Communicable Diseases | Altered Intercellular Communication | CD57+ T cells have been associated with inflammatory conditions, but their potential role in the response against infectious disease and vaccination should now be investigated. | 27566833 |
| Optimism, Inflammation, Fracture, Hostility | Altered Intercellular Communication | Traits of optimism and cynical hostility are features of personality that could influence the risk of falls and fractures by influencing risk-taking behaviors, health behaviors, or inflammation. | 27566996 |
| Sjogrens Syndrome | Altered Intercellular Communication | Interleukin-15 as a potential new target in Sjogren's syndrome-associated inflammation. | 27567226 |
| allergic inflammation | Altered Intercellular Communication | Pentraxin 3 deletion aggravates allergic inflammation through a TH17-dominant phenotype and enhanced CD4 T-cell survival. | 27567326 |
| Communicable Diseases, Inflammation | Altered Intercellular Communication | It is produced at sites of infection and inflammation by both structural and inflammatory cells. | 27567326 |
| Asthma, allergic inflammation | Altered Intercellular Communication | We sought to determine the effect of Ptx3 deletion on ovalbumin (OVA)-induced allergic inflammation in a murine model of asthma. | 27567326 |
| Respiratory Hypersensitivity, Eosinophilic inflammation | Altered Intercellular Communication | Mice lacking PTX3 have exaggerated neutrophilic/eosinophilic lung inflammation, mucus production, and airway hyperresponsiveness in an experimental model of OVA-induced asthma. | 27567326 |
| Respiratory Hypersensitivity, allergic inflammation, Pneumonitis | Altered Intercellular Communication | Altogether, PTX3 deficiency results in augmented airway hyperresponsiveness, mucus production, and IL-17A-dominant pulmonary inflammation, suggesting a regulatory role of PTX3 in the development of allergic inflammation. | 27567326 |
| Inflammation, Data types - Address | Altered Intercellular Communication | The growing appreciation of the importance of inflammation in early AD has focused attention on inflammatory biomarkers in cerebrospinal fluid or plasma; however, non-specific inflammation markers have disappointed to date. | 27567854 |
| Inflammation, Data types - Address | Altered Intercellular Communication | Complement, a core system in innate immune defense and potent driver of inflammation, has been implicated in pathogenesis of AD based on a confluence of genetic, histochemical, and model data. | 27567854 |
| Inflammation, Malignant Neoplasms | Altered Intercellular Communication | Increasing evidence indicates that inflammation may play important roles in tumorigenesis and progression, and an elevated peripheral monocyte count predicts a poor prognosis in various types of malignancies. | 27569002 |
| Inflammation, Cardiovascular Diseases, Dyslipidemias, Decreased renal function, Hypophosphatemia | Altered Intercellular Communication | In addition to decreased renal function, dyslipidemia, inflammation, and continuing hypophosphatemia were also accompanied by decreased BMD as in cardiovascular disease in KTrs. | 27569941 |
| Inflammation, osteoclast activating factor, Atrial Fibrillation by ECG Finding | Altered Intercellular Communication | POAF may represent a propensity for recurrent paroxysmal atrial fibrillation, and not simply a transient consequence of postoperative stress and inflammation. | 27570120 |
| Inflammation, Arthritis, Cerebrovascular accident | Altered Intercellular Communication | However, the least prevalent diseases were stroke (17.2%), joint inflammation (17.2%), and arthritis (9.0%). | 27570449 |
| Retinal Detachment, Inflammation | Altered Intercellular Communication | Clinical examination of the patient revealed anterior and posterior inflammation and bilateral serous retinal detachments. | 27571426 |
| Inflammation, Serous retinal detachment | Altered Intercellular Communication | Subsequent 6-month follow-up demonstrated complete resolution of the inflammation and bilateral serous detachments after completion of the prednisone taper over a 3-month period. | 27571426 |
| Have Autoimmune or Inflammatory Condition | Altered Intercellular Communication | This form of autoimmune inflammation may occur after the recovery of T-cell activity within the donor graft targeting the host. | 27571426 |
| Inflammation, Sarcopenia | Altered Intercellular Communication | Serum markers of inflammation and oxidative stress in sarcopenia. | 27571781 |
| Inflammatory Bowel Diseases, Inflammation | Altered Intercellular Communication | Relationship of clinical symptoms with biomarkers of inflammation in pediatric inflammatory bowel disease. | 27573259 |
| Inflammatory Bowel Diseases, Inflammation | Altered Intercellular Communication | In adult inflammatory bowel disease (IBD) patients, there is a strong discrepancy between symptoms and biomarkers of inflammation. | 27573259 |
| Inflammatory Bowel Diseases, Inflammation | Altered Intercellular Communication | Therefore, we aimed to investigate the relationship between clinical symptoms and biomarkers of inflammation in pediatric IBD. | 27573259 |
| Inflammatory Bowel Diseases, Inflammation | Altered Intercellular Communication | There is a strong discrepancy between clinical symptoms and biomarkers of inflammation in children with IBD. | 27573259 |
| Inflammatory Bowel Diseases, Inflammation | Altered Intercellular Communication | * A substantial proportion of asymptomatic pediatric inflammatory bowel disease (IBD) patients have elevated biomarkers of inflammation. | 27573259 |
| Inflammatory Bowel Diseases, Inflammation | Altered Intercellular Communication | * There is a strong discrepancy between symptoms and biomarkers of inflammation in adults with IBD. | 27573259 |
| Inflammatory Bowel Diseases, Inflammation | Altered Intercellular Communication | * Similarly to adult IBD patients, there is a strong discrepancy between clinical symptoms and biomarkers of inflammation in children with IBD. | 27573259 |
| Inflammation, Impaired T cell function, Intimal proliferation | Altered Intercellular Communication | PKCe mediates resistin-induced NADPH oxidase activation and inflammation leading to smooth muscle cell dysfunction and intimal hyperplasia. | 27573736 |
| Airway structure | Altered Intercellular Communication | BHR is mediated via airway smooth muscle tone and is modulated by the autonomic nervous system, nitric oxide, and airway inflammation. | 27574738 |
| Inflammation, Bronchopulmonary Dysplasia | Altered Intercellular Communication | No associations with systemic soluble markers of inflammation were observed for Met-BHR, birth, or BPD status. | 27574738 |
| Asthma | Altered Intercellular Communication | Airway neutrophilic inflammation is a pathological feature in some patients with severe asthma. | 27574788 |
| Inflammation | Altered Intercellular Communication | H pylori organisms were prospectively identified in 23 (7%) patients, all of whom had superficial dense lymphoplasmacytic inflammation expanding the lamina propria. | 27574809 |
| Hematoxylin and eosin stain method, Inflammation | Altered Intercellular Communication | One patient diagnosed as having normal gastric mucosa was retrospectively found to have inflammation with rare H pylori organisms originally overlooked on both H&E and Diff-Quik but later identified on immunostain (0.5%). | 27574809 |
| Inflammation, Gastritis | Altered Intercellular Communication | No patients with chemical gastritis (16%) or chronic inflammation (27%) were found to have H pylori. | 27574809 |
| Hematoxylin and eosin stain method, Inflammation | Altered Intercellular Communication | The organisms can be seen on routine H&E; when suspicious superficial or active inflammation is present without visible organisms, immunohistochemical stains will confirm presence or absence within a day. | 27574809 |
| Inflammation, Thrombosis, Cerebrovascular accident | Altered Intercellular Communication | Endothelial Function, Inflammation, Thrombosis, and Basal Ganglia Perivascular Spaces in Patients with Stroke. | 27576214 |
| ACSM3 gene, Inflammation, Neurologic Deficits | Altered Intercellular Communication | Dynamic changes in the levels of these cytokines may induce inflammation and may be closely associated with the development of delayed ischemic neurological deficits after SAH. | 27576738 |
| Inflammation, Appendicitis, CTCAE, Rupture | Altered Intercellular Communication | Appendicitis was defined as acute inflammation, rupture or abscess of the appendix on pathologic evaluation. | 27577252 |
| Acute Kidney Injury, CTCAE, Inflammation, Obesity | Altered Intercellular Communication | The Influence of Thyroid Function, Inflammation, and Obesity on Risk Prediction of Acute Kidney Injury by Cystatin C in the Emergency Department. | 27578194 |
| Inflammation, Obesity | Altered Intercellular Communication | Cystatin C (CysC), a newer renal biomarker, is influenced by thyroid function, inflammation and obesity. | 27578194 |
| Inflammation, Kidney Failure, Acute, Obesity | Altered Intercellular Communication | CysC is known to be influenced by thyroid function, inflammation and obesity, but in our large ED population there was no significant impact of these factors on the diagnostic accuracy of CysC to detect AKI in ED patients. | 27578194 |
| Inflammation, Myopathy, Myositis | Altered Intercellular Communication | Glucocorticoids (GCs), although effective at suppressing inflammation and inflammatory muscle loss, also cause myopathy with prolonged administration. | 27578244 |
| Inflammation, Tumor necrosis | Altered Intercellular Communication | The expression of 11b-HSD1 in response to proinflammatory stimuli was determined in a transgenic murine model of chronic inflammation (TNF-Tg) driven by overexpression of tumour necrosis factor (TNF)-a within tissues, including muscle. | 27578244 |
| Cachexia, Myositis | Altered Intercellular Communication | The contributions of 11b-HSD1 to muscle inflammation and wasting were assessed in vivo with the TNF-Tg mouse on an 11b-HSD1 null background. | 27578244 |
| Inflammation, Carcinogenesis, Neoplasms | Altered Intercellular Communication | TNFAIP8L2 (TIPE2 or tumor necrosis-alpha-induced protein-8 like 2) is a negative regulator for inflammation and an inhibitor for carcinogenesis. | 27578327 |
| Inflammation, Asthma | Altered Intercellular Communication | In 1042 subjects with refractory asthma recruited to the British Thoracic Society Severe Asthma Registry, we compared patient demographics, disease characteristics and biomarkers of inflammation in patients aged <65 years (n = 896) versus >=65 years (n = 146) and onset at age <18 years (n = 430) versus >=18 years (n = 526). | 27578470 |
| Shock, Inflammation, Sepsis | Altered Intercellular Communication | sST2 might have a role as a biomarker of shock or inflammation, but it cannot reflect echocardiographic findings of LV ejection fraction or diastolic filling in sepsis. | 27578513 |
| Inflammation | Altered Intercellular Communication | This may be related to increased uveoscleral outflow and intraocular inflammation after RRD, and it may be concluded that vitrectomy does not affect choroidal thickness. | 27579730 |
| Inflammation, Obesity | Altered Intercellular Communication | Angiogenesis in inflammation are hallmarks for adipose tissue expansion in obesity. | 27581034 |
| Proctitis | Altered Intercellular Communication | However, the effect of chronic EtOH consumption on CYP2E1, etheno-DNA adducts as well as anti-apoptotic proteins in the colorectal mucosa of heavy drinkers without colorectal inflammation is still not known. | 27581253 |
| Inflammation, Adenoma | Altered Intercellular Communication | The positive rates in conventional adenomas (24.0%, n = 146) and hyperplastic nodules (100%, n = 17) were each different from that found in inflammation (70.8%, n = 24), and spiral organisms were seen more frequently in the right-side large intestine than in the left (within mucus, 100%, n = 104 versus 95.0%, n = 119; within crypts, 65.4%, n = 104 versus 49.6%, n = 119). | 27581381 |
| Inflammation, hepcidin | Altered Intercellular Communication | Inflammation was present at delivery, which limited the utility of ferritin or hepcidin as iron-status indicators at delivery. | 27581469 |
| Inflammatory abnormality of the eye | Altered Intercellular Communication | Of 10 eyes, 5 showed moderate to severe ocular inflammation within a few days of injection. | 27582674 |
| Inflammation, Diabetes Mellitus, Non-Insulin-Dependent | Altered Intercellular Communication | This study demonstrates that linagliptin tends to improve endothelial and neurovascular microvascular function and is associated with decreased markers of inflammation in patients with type 2 diabetes. | 27583476 |
| Tip of appendix, Enterobiasis | Altered Intercellular Communication | Enterobius vermicularis infestation of the appendix can cause symptoms of appendiceal pain, independent of microscopic evidence of acute inflammation. | 27585284 |
| Inflammation, Appendicitis, CTCAE, Enterobiasis | Altered Intercellular Communication | We highlight that the symptoms of appendicitis can be due to Enterobius vermicularis infestation also without any histological evidence of acute inflammation. | 27585284 |
| Intraocular inflammation, Tularemia | Altered Intercellular Communication | In this paper, we report a case of intraocular inflammation during tularemia infection. | 27585457 |
| Communicable Diseases, Uveitis, Tularemia, Intraocular inflammation | Altered Intercellular Communication | Posterior uveitis may be an infrequent manifestation of tularemia infection, and therefore this infection should be considered in the differential diagnosis of intraocular inflammation in areas where F. tularensis is endemic. | 27585457 |
| Inflammation | Altered Intercellular Communication | Network analysis combined with a novel technique for biomarker computation allowed the identification of an alteration in aging-associated processes such as inflammation, oxidative stress and metabolic pathways, indicating that APOE4 possibly accelerates pathological processes physiologically induced by aging. | 27585646 |
| Inflammation, "Alzheimers Disease | Altered Intercellular Communication | In conclusion, APOE4 role on inflammation and oxidation through the Notch signaling pathway could be crucial in elucidating the risk factors of Alzheimer's disease. | 27585646 |
| Inflammation, Hepatocarcinogenesis | Altered Intercellular Communication | Sympathetic nervous system promotes hepatocarcinogenesis by modulating inflammation through activation of alpha1-adrenergic receptors of Kupffer cells. | 27585737 |
| Inflammation, Liver carcinoma, FAM126A gene, Hyperactive behavior, Liver Cirrhosis | Altered Intercellular Communication | Hepatocellular carcinoma (HCC) frequently occurs in cirrhotic livers after chronic inflammation, and the SNS is hyperactive in advanced liver cirrhosis. | 27585737 |
| Hepatitis, Chronic, Hepatocarcinogenesis | Altered Intercellular Communication | However, it remains unclear whether the SNS promotes hepatocarcinogenesis by modulating chronic liver inflammation. | 27585737 |
| Degenerative polyarthritis, Inflammation, Atherosclerosis | Altered Intercellular Communication | Recent studies have reported that osteoarthritis (OA) is related to inflammation and atherosclerosis. | 27585925 |
| Inflammation, Infection | Altered Intercellular Communication | Increasing the ceftaroline fosamil dose beyond 600 mg every 12 h may provide additional benefit for patients with complicated skin and soft tissue infections (cSSTIs) with severe inflammation and/or reduced pathogen susceptibility. | 27585969 |
| Inflammation | Altered Intercellular Communication | This suggests that hBD-1 has a more constitutive role in host defense in the vocal cords, whereas hBD-2 expression may be a result of local inflammation or the presence of invading pathogens. | 27586391 |
| Inflammation, Depression, CTCAE | Altered Intercellular Communication | Not only is depression associated with increased inflammation but inflammation is a risk factor for the genesis of depression. | 27587328 |
| Inflammation, Depression, CTCAE | Altered Intercellular Communication | ASPREE-D may not only define novel therapy but will provide mechanistic proof of concept of the role of inflammation in depression. | 27587328 |
| Tumor necrosis, Inflammation | Altered Intercellular Communication | M2BP abrogated the suppressive effects of APN on tumour necrosis factor (TNF)-a-induced inflammation in vascular endothelial cells. | 27588936 |
| Inflammation, Fracture, Hyperuricemia, Gout | Altered Intercellular Communication | This prospective study was undertaken to examine the relationship between gout, a disease characterized by hyperuricemia and inflammation, and risk of hip or wrist fracture in women. | 27589491 |
| Inflammation, Liver carcinoma, Communicable Diseases, Hepatitis B, Hepatitis C, FAM126A gene | Altered Intercellular Communication | Hepatocellular carcinoma (HCC) is associated with inflammation, and roughly 30 % of the global population shows serological evidence of current or past infection with hepatitis B or hepatitis C virus. | 27589954 |
| Inflammation, Leucocytic infiltrate | Altered Intercellular Communication | In mice with selective IL-6 ablation in monocytes/KCs, we observed decreased toxic liver injury, inflammatory infiltration, and systemic inflammation. | 27589954 |
| Pyelonephritis, Xanthogranulomatous, Inflammation, Fever, CTCAE | Altered Intercellular Communication | A 70-year-old male patient underwent left-sided nephrectomy for signs and symptoms that were suggestive of xanthogranulomatous pyelonephritis (recurrent fever, swollen malfunctioning kidney, granulomatous inflammation in renal biopsy). | 27590254 |
| Inflammation, Alkaptonuria | Altered Intercellular Communication | Comparative proteomics in alkaptonuria provides insights into inflammation and oxidative stress. | 27590860 |
| Inflammation, Rheumatism | Altered Intercellular Communication | Interesting similarities with proteomic studies on other rheumatic diseases were highlighted together with proteome alterations supporting the existence of oxidative stress and inflammation in AKU. | 27590860 |
| Inflammation | Altered Intercellular Communication | In contrast, the endogenous opioid system has an important analgesic action during chronic inflammation. | 27590998 |
| Inflammatory Bowel Diseases, Pain Distress Question, Inflammatory disorder | Altered Intercellular Communication | Psychological stress accompanies chronic inflammatory diseases such as IBD, and stress hormones can exacerbate pain signalling. | 27590998 |
| Inflammation, Fatigue | Altered Intercellular Communication | Systemic inflammation was not associated with perception of fatigue but surfactant protein D was connected to some dimensions of the impact of fatigue. | 27591046 |
| Crohns disease of the ileum", Inflammation, Ileitis | Altered Intercellular Communication | In summary, Crohn's disease ileitis is often associated with inflammation elsewhere in the gastrointestinal tract while non-specific ileitis was infrequently associated with inflammation elsewhere for both paediatric and adult patients. | 27591764 |
| Cholangitis, Primary Biliary Cholangitis | Altered Intercellular Communication | Hydrophobic bile acids suppress expression of AE2 in biliary epithelial cells and induce bile duct inflammation in primary biliary cholangitis. | 27592379 |
| Inflammation, Primary Biliary Cholangitis | Altered Intercellular Communication | Understanding the mechanisms of chronic inflammation in primary biliary cholangitis (PBC) is essential for successful treatment. | 27592379 |
| Inflammation, Thrombosis | Altered Intercellular Communication | Platelets are major players in haemostasis and thrombosis and are involved in inflammation. | 27593518 |
| Inflammation, Incontinence | Altered Intercellular Communication | Impact of Periurethral Inflammation on Continence Status Early After Robot-Assisted Radical Prostatectomy. | 27597311 |
| Bronchopulmonary Dysplasia, Pneumonitis, Hypertrophy | Altered Intercellular Communication | Heterozygous Crispld2+/- mice display features of BPD, including distal airspace enlargement, disruption of elastin, and neonatal lung inflammation. | 27597766 |
| Inflammation | Altered Intercellular Communication | RNA sequencing results from HLF-CRISPLD2(knockdown) suggest roles for CRISPLD2 in extracellular matrix and in inflammation. | 27597766 |
| Pneumonitis | Altered Intercellular Communication | Our data suggest that suppression of CRISPLD2 increases the risk of lung inflammation in early life and adulthood. | 27597766 |
| Inflammation, Demographics Domain, Diabetes Mellitus, Microcirculation disorders, Intestinal Motility | Altered Intercellular Communication | Clinical and experimental research has revealed that diabetes mellitus (DM) is characterized by intestinal hypomotility, gut microbial dysbiosis, increased gut permeability, microcirculation disorders, circulatory changes, and dysfunction of intestinal stem cells, which may be linked to inflammation of intestinal mucosa. | 27598308 |
| Inflammation, Appendicitis, CTCAE, Obstruction | Altered Intercellular Communication | Obstruction and inflammation of the appendix lumen is the leading physiopathological process during acute appendicitis (AA). | 27598605 |
| Inflammation, Congenital Abnormality | Altered Intercellular Communication | Several alternative reasons including congenital malformations and chronic inflammation have been identified as a cause of CAE. | 27598894 |
| Coronary artery ectasia, Inflammation | Altered Intercellular Communication | We also elucidate the recently proposed markers of chronic inflammation that might be associated with coronary artery ectasia. | 27598894 |
| Inflammation | Altered Intercellular Communication | Infiltration of inflammatory cells, most of which were lymphocytes, was also observed in the dermis and the epidermis in all cases, even though there were no clinical signs of inflammation. | 27599121 |
| Inflammation | Altered Intercellular Communication | Choroidal lesions were associated with clinical signs of inflammation, suggesting that they represent foci of disease activity. | 27599125 |
| Inflammation | Altered Intercellular Communication | Long-term barrier impairment might lead to chronic inflammation. | 27599552 |
| Inflammation, Atrophic nonunion of fracture | Altered Intercellular Communication | Biomarkers of inflammation and innate immunity in atrophic nonunion fracture. | 27599571 |
| Inflammation, Atrial Fibrillation by ECG Finding | Altered Intercellular Communication | Many studies have found that systemic inflammation plays an important role in the pathogenesis of atrial fibrillation (AF). | 27599578 |
| palladium, Inflammation, Metabolic Syndrome X, MS gene | Altered Intercellular Communication | Low-grade chronic inflammation is present in patients on peritoneal dialysis (PD) and in metabolic syndrome (MS). | 27600388 |
| palladium, Inflammation, Metabolic Diseases | Altered Intercellular Communication | In patients on PD, inflammatory reaction is higher than in patients with MS. On the contrary, patients with MS have stronger oxidative stress response and adipose tissue activity caused probably by the chronic low level of inflammation and underlying metabolic disorders. | 27600388 |
| Inflammation, Obesity, Abdominal, Microalbuminuria, Hypertriglyceridemia, Endothelial dysfunction, Hypertension, CTCAE | Altered Intercellular Communication | Patients with MS had increased abdominal obesity, hypertension, hypertriglyceridemia, inflammation factors, IR, homocysteine and microalbuminuria as markers of endothelial dysfunction. | 27600468 |
| Infarction, Inflammation | Altered Intercellular Communication | Multiplex immunoassay characterization and species comparison of inflammation in acute and non-acute ischemic infarcts in human and mouse brain tissue. | 27600707 |
| Presenile dementia, Inflammation | Altered Intercellular Communication | The study goal was to address the hypothesis that chronic inflammation may contribute to stroke-related dementia. | 27600707 |
| Inflammation, Renal Cell Carcinoma Pathway, Sarcopenia | Altered Intercellular Communication | Sarcopenia, or the degenerative loss of skeletal muscle mass, develops as a consequence of cancer-host interactions, including systemic inflammation and poor nutritional status, and is associated with a poor prognosis in patients with metastatic renal cell carcinoma (mRCC). | 27601279 |
| Communicable Diseases, Inflammation | Altered Intercellular Communication | During an infection or inflammation, several drug-metabolizing enzymes in the liver are down-regulated, including cytochrome P450 iso-enzymes. | 27601292 |
| Inflammation, Necrosis | Altered Intercellular Communication | Wound necrosis was distinctly associated with pathogenic fungal species, while taxa identified as allergenic filamentous fungi were associated with low levels of systemic inflammation. | 27601572 |
| Inflammation, Electrocardiogram: myocardial infarction (finding), Cardiac Death, Cerebrovascular accident | Altered Intercellular Communication | Gamma-glutamyl transferase (gamma-GT) is an enzyme present in the cell membranes, which is used as a new biomarker in prediction of inflammation, myocardial infarction, stroke, and cardiac death. | 27601721 |
| Inflammation | Altered Intercellular Communication | Our data suggest that the same dose of UV radiation induces significantly more inflammation in the morning than in the afternoon. | 27602977 |
| Communicable Diseases, pustule, Ki-1+ Anaplastic Large Cell Lymphoma | Altered Intercellular Communication | It is also important that clinicians recognize atypical clinical morphologies of cutaneous ALCL, including pustular lesions, which may masquerade as infectious or other inflammatory conditions, thereby delaying the onset of treatment. | 27602978 |
| Perifolliculitis | Altered Intercellular Communication | Recent surveys across the Solomon Islands indicated that whilst trachomatous inflammation-follicular (TF) was present at levels warranting intervention, the prevalence of trachomatous trichiasis (TT) was low. | 27603015 |
| Communicable Diseases, Tissue Factor | Altered Intercellular Communication | We observed a moderate prevalence of TF in children aged 1-9 years (n = 296/1135, 26.1%) but low prevalence of trachomatous inflammation-intense (TI) (n = 2/1135, 0.2%) and current Ct infection (n = 13/1002, 1.3%) in children aged 1-9 years, and TT in those aged 15+ years (n = 2/2061, 0.1%). | 27603015 |
| Inflammation, HIV-1 Infection Pathway | Altered Intercellular Communication | Oxidized lipoproteins are associated with markers of inflammation and immune activation in HIV-1 infection. | 27603288 |
| Inflammation | Altered Intercellular Communication | Surgical findings and pathologic results confirmed the diagnosis of small intestinal heterotopic pancreas with active chronic inflammation. | 27603341 |
| Inflammation, Coronary heart disease, Choline Dehydrogenase, Mitochondrial | Altered Intercellular Communication | Given both smoking and vitamin D are associated with coronary heart disease (CHD) via inflammation and smoking may interfere with the local antiinflammatory effects of vitamin D. We hypothesized that the relationship between smoking and severity of CHD may be modified by vitamin D.A cross-sectional study was conducted. | 27603397 |
| Inflammation, Cerebrovascular accident | Altered Intercellular Communication | Lifestyle, including dietary patterns, could involve specific factors participating in inflammation that confer a higher risk of suffering a stroke. | 27603597 |
| Inflammation | Altered Intercellular Communication | Increased 18F-FDG uptake was seen in the myocardial wall in three patients, indicating active inflammation. | 27604109 |
| Inflammation | Altered Intercellular Communication | Eventually, a facial skin biopsy was performed showing nonspecific chronic inflammation only. | 27604462 |
| Inflammation, Hematoma, Inguinal pain, Seroma, Testis | Altered Intercellular Communication | Secondary outcomes were short and long-term complications: hematoma and seroma formation, inflammation of the testis, chronic inguinal pain, reoperation, 30 days mortality. | 27604667 |
| Inflammation, Critical Illness, Liver Dysfunction, Hypoperfusion, Kidney Diseases | Altered Intercellular Communication | Herein, urinary neutrophil gelatinase-associated lipocalin (NGAL), L-type fatty acid-binding protein (L-FABP) and nonrenal disorders, including inflammation, hypoperfusion and liver dysfunction, were evaluated in 249 critically ill patients treated at our intensive care unit. | 27605390 |
| Inflammation, Heart failure | Altered Intercellular Communication | Salivary Biomarkers, Oral Inflammation, and Functional Status in Patients With Heart Failure. | 27605566 |
| Immunologic Deficiency Syndromes, Inflammation, Sinusitis, Malignant Head and Neck Neoplasm | Altered Intercellular Communication | Chronic sinusitis may be involved in the etiology of certain head and neck cancers (HNCs), due to immunodeficiency or inflammation. | 27606895 |
| Inflammation | Altered Intercellular Communication | Clearance of autophagy-associated dying retinal pigment epithelial cells - a possible source for inflammation in age-related macular degeneration. | 27607582 |
| Cessation of life, Inflammation, methyldopa | Altered Intercellular Communication | Our data suggest that cells undergoing autophagy-associated cell death engage in clearance mechanisms guided by professional and non-professional phagocytes, which is accompanied by inflammation as part of an in vitro modeling of AMD pathogenesis. | 27607582 |
| Lichen Planus, Inflammation, Dyslipidemias | Altered Intercellular Communication | Epicardial fat tissue thickness is increased in patients with lichen planus and is linked to inflammation and dyslipidemia. | 27609552 |
| Inflammation, Atherosclerosis | Altered Intercellular Communication | Inflammation plays a major role in the progression of atherosclerosis. | 27609552 |
| Inflammation, Non-alcoholic Fatty Liver Disease | Altered Intercellular Communication | Sitting time was positively associated with the prevalence of NAFLD, and this association might be affected by inflammation. | 27609847 |
| CLU protein, human | Altered Intercellular Communication | Compared to IC, CLI is a systemic inflammatory condition, which may explain the extremely poor outcome associated with it. | 27611073 |
| Respiratory Distress Syndrome, Adult, Inflammation | Altered Intercellular Communication | To assess whether sevoflurane would improve gas exchange and inflammation in ARDS. | 27611637 |
| Inflammation, COL4A2 wt Allele | Altered Intercellular Communication | Herby we assessed the relevance of systemic inflammation in patients suffering ICH. | 27611984 |
| Granulomatous Mastitis, Primary malignant neoplasm, Immunoglobulin M | Altered Intercellular Communication | Idiopathic granulomatous mastitis (IGM) is a chronic inflammatory condition that is confused with cancer. | 27612044 |
| ARCN1 gene, Inflammation | Altered Intercellular Communication | Susceptibility for cigarette smoke-induced DAMP release and DAMP-induced inflammation in COPD. | 27612964 |
| ARCN1 gene, Inflammation, Moist | Altered Intercellular Communication | We investigated whether CS-induced damage-associated molecular pattern (DAMP) release or DAMP-mediated inflammation contributes to susceptibility for COPD. | 27612964 |
| Airway structure | Altered Intercellular Communication | LL-37 and mtDAMPs induced neutrophilic airway inflammation, exclusively in mice susceptible for CS-induced airway inflammation. | 27612964 |
| ARCN1 gene, Inflammation | Altered Intercellular Communication | Furthermore, our studies indicate that a predisposition to release DAMPs and subsequent induction of inflammation may contribute to the development of COPD. | 27612964 |
| Inflammation | Altered Intercellular Communication | To examine whether patients with a mature normal pouch [> 1 year post ileostomy closure] have microbial stool characteristics that can predict pouch inflammation. | 27613294 |
| Inflammation, Exanthema, Skin irritation | Altered Intercellular Communication | Moulded orthoses can have defects after manufacturing that can lead to localised skin irritation, inflammation and subsequent rash formation. | 27613591 |
| Inflammation, Liver carcinoma | Altered Intercellular Communication | Immune inflammation indicators and implication for immune modulation strategies in advanced hepatocellular carcinoma patients receiving sorafenib. | 27613839 |
| ARCN1 gene, Inflammation, Chronic Obstructive Airway Disease | Altered Intercellular Communication | Chronic obstructive pulmonary disease (COPD) is characterized by chronic inflammation that leads to excessive remodeling of the lung extracellular matrix (ECM), resulting in release of protein fragments (neo-epitopes) to the blood. | 27614218 |
| Perforation (observation), Necrosis, Infertility, Stenosis Morphology, Pelvic Inflammatory Disease | Altered Intercellular Communication | Early removal of foreign objects prevents ulceration, necrosis, stenosis, perforations, and late serious sequelae such as pelvic inflammation and infertility. | 27614288 |
| Inflammation, Hypercholesterolemia, atherosclerotic | Altered Intercellular Communication | Background Inflammation and hypercholesterolaemia contribute to atherosclerotic changes which can start in childhood. | 27614353 |
| Inflammation, Primary malignant neoplasm | Altered Intercellular Communication | The neutrophil-to-lymphocyte ratio (NLR) is a marker of systemic inflammation associated with recurrence and poor prognosis in numerous cancer types. | 27614622 |
| Inflammation, Cerebrovascular accident | Altered Intercellular Communication | This brain-spleen cell cycling after stroke affects systemic inflammation and the brain inflammatory milieu and may be a target for emerging therapeutic studies. | 27615448 |
| Glomerulonephritis, Glomerular capillaries structure | Altered Intercellular Communication | Glomerular endocapillary inflammation may result in crescent formation and exuded protein leakage, which may induce TII in antineutrophil cytoplasmic antibody-associated glomerulonephritis (ANCAGN). | 27616759 |
| Inflammation | Altered Intercellular Communication | Sterile inflammation leads to the formation of ANCA-mediated neutrophil extracellular traps (NETs), which may stimulate macrophages and dendritic cells via TLR4 and induce NF-kB-dependent mRNA expression and translation of pro-IL-1b. | 27616759 |
| Inflammation | Altered Intercellular Communication | Sterile inflammation utilizing the NLRP3 inflammasome might be a characteristic reaction limited to the tubulointerstitium. | 27616759 |
| Inflammation, Fever, CTCAE | Altered Intercellular Communication | The diagnostic strategy in patients with fever or inflammation of unknown origin remains a major clinical challenge. | 27617327 |
| Inflammation | Altered Intercellular Communication | 18F-FDG-PET/CT is a useful method in the diagnostic workup of patients with inflammation of unknown origin. | 27617327 |
| Inflammation, Fever, CTCAE | Altered Intercellular Communication | Regarding 18F-FDG-PET/CT-imaging inflammation of unknown origin and unexplained fever can be joined to one entity. | 27617327 |
| Necrotizing granulomatous inflammation, Fat necrosis, Fibrosis Assessment | Altered Intercellular Communication | Biopsy demonstrated focal lobular and septal granulomatous inflammation admixed with septal fibrosis and lobular lymphohistiocytic infiltrate associated with fat necrosis. | 27617607 |
| Inflammation, Observation Method - Coagulation | Altered Intercellular Communication | Neutrophil extracellular traps (NETs) are found to trigger inflammation and coagulation. | 27617671 |
| Inflammation, vinyltriethoxysilane | Altered Intercellular Communication | The NETs formation correlated positively with the VTE risk, rather than the parameters of inflammation or disease severity. | 27617671 |
| Sepsis, Inflammation, vinyltriethoxysilane | Altered Intercellular Communication | The systemic inflammation during sepsis primes neutrophils to release NETs with increased risk of VTE. | 27617671 |
| Orchitis, Diverticulosis, Diverticular Diseases | Altered Intercellular Communication | Diverticular inflammation and complication assessment (DICA) endoscopic classification has been recently developed for patients suffering from diverticulosis and diverticular disease. | 27622352 |
| Inflammation, Diverticular Diseases | Altered Intercellular Communication | Also, the criteria for symptomatic uncomplicated diverticular disease in the absence of macroscopic inflammation are not clearly defined. | 27622376 |
| Inflammation | Altered Intercellular Communication | Musculoskeletal ultrasound: an effective tool to help medical students improve joint inflammation detection? | 27622404 |
| Inflammation | Altered Intercellular Communication | MSUS may be an effective technique for helping students to acquire the ability to detect joint inflammation. | 27622404 |
| Gingivitis, Periodontitis, Bacteremia, Diabetes Mellitus | Altered Intercellular Communication | This would be the case of patients with diabetes mellitus and periodontitis, who exhibit exacerbated gingival inflammation and may be more prone to developing oral-derived bacteremia. | 27622449 |
| Inflammation, Ulcerative Colitis | Altered Intercellular Communication | Ulcerative colitis (UC), a chronic inflammation of the colon, is often more severe in children than adults. | 27622899 |
| Inflammation | Altered Intercellular Communication | These data suggest a function for NK cells in the pathogenesis and/or modulation of inflammation in GPA. | 27624647 |
| Arthritis, Inflammatory abnormality of the eye, Fever, CTCAE | Altered Intercellular Communication | Interestingly, the ocular inflammation resolved completely following therapeutic vitrectomy in both eyes whereas the systemic symptoms of fever and arthritis continued to wax and wane while on treatment with oral methotrexate and corticosteroids. | 27625029 |
| Inflammation, Pre-Eclampsia | Altered Intercellular Communication | Preeclampsia reflects an unusual increase in systemic inflammation during pregnancy. | 27626972 |
| Communicable Diseases, Inflammation | Altered Intercellular Communication | Treatment of the cells with antioxidant agents just after infection completely abolished TNF secretion, indicating an involvement of ROS in inflammation induced during MAYV infection. | 27627069 |
| Inflammation, Obesity | Altered Intercellular Communication | Alterations in endocrine functions and low-grade systemic inflammation represent fundamental characteristics of obesity. | 27627133 |
| Fatigue | Altered Intercellular Communication | The possibility that inflammation-induced alterations in tryptophan metabolism relates to specific dimensions of fatigue was also investigated in a subsample of patients. | 27627133 |
| Refractory anemias, Inflammation, Rheumatoid Arthritis, Infiltration | Altered Intercellular Communication | Multiple lymphocyte subsets like T and B cells have been connected to joint infiltration and inflammation in rheumatoid arthritis (RA). | 27629388 |
| Weight decreased, Gastrointestinal inflammation | Altered Intercellular Communication | Ingestion of 2'-FL by mice reduced C. jejuni colonization by 80%, weight loss by 5%, histologic features of intestinal inflammation by 50-70%, and induction of inflammatory signaling molecules of the acute-phase mucosal immune response by 50-60% (P < 0.05). | 27629573 |
| Weight decreased, Gastrointestinal inflammation | Altered Intercellular Communication | Ingestion of 2'-FL by mice reduced C. jejuni colonization by 80%, weight loss by 5%, histologic features of intestinal inflammation by 50-70%, and induction of inflammatory signaling molecules of the acute-phase mucosal immune response by 50-60% (P < 0.05). | 27629573 |
| Inflammation, Fibrosis Assessment, Heart failure | Altered Intercellular Communication | Galectin-3 (Gal-3) as a biomarker of fibrosis and inflammation has been implicated in the development and progression of heart failure (HF) and may predict increased morbidity and mortality in society. | 27629834 |
| Inflammation, Hemorrhage, Structure of porta hepatis, Neoplasms, Aneurysm | Altered Intercellular Communication | A 66-year-old man, with an abnormal porta hepatis, consistent with tumor or inflammation, developed massive bleeding from one of numerous hepatic artery aneurysms, and coil embolization achieved control of bleeding. | 27630223 |
| Inflammation, Liver carcinoma, Hepatitis C | Altered Intercellular Communication | The study population was 82 adult Japanese patients who had chronic inflammation due to HCV infection diagnosed by pathological examination of liver biopsy specimens, including 21 patients with early hepatocellular carcinoma (eHCC) and HCV-related LC. | 27630292 |
| Gallbladder Carcinoma | Altered Intercellular Communication | Preoperative Systemic Inflammation and Complications Affect Long-term Gallbladder Carcinoma Outcomes Following Surgery with Curative Intent. | 27630345 |
| Inflammation, Prostatic Intraepithelial Neoplasias, Hyperplasia, Prostate carcinoma | Altered Intercellular Communication | Patients were stratified by final pathology reports of RARP specimens: Group I: Prostate cancer, N=22 (40%); group II: abnormal (prostate intraepithelial neoplasia; atypical small acinar proliferation), N=18 (32.7%); and group III: benign (nodular hyperplasia or inflammation), N=15 (27.3%). | 27630346 |
| Inflammation, Bipolar Disorder, Cardiovascular Diseases | Altered Intercellular Communication | Low vitamin D and depressive symptoms are associated with inflammation activation that predicts cardiovascular disease. | 27631120 |
| Hepatic inflammation, Complete atrioventricular block, Hepatitis B, fibrogenesis | Altered Intercellular Communication | The mechanisms underlying hepatic inflammation and fibrogenesis in chronic hepatitis B (CHB) are complex and several cytokines are involved. | 27631226 |
| Temporomandibular Joint Disorders, Pain Distress Question, Inflammation | Altered Intercellular Communication | In the eyes with presumed TMD, patients denied pain or inflammation. | 27631347 |
| Inflammation, Hyperemia, Pain Distress Question | Altered Intercellular Communication | In the 4 patients with a clinical history of inflammation (bulbar hyperemia and pain), and in the 1 patient with active inflammation at the time of HR-OCT imaging, HR-OCT also demonstrated thinning with an intact epithelium. | 27631347 |
| Temporomandibular Joint Disorders, Inflammation | Altered Intercellular Communication | In contrast to the TMD group, in the group with signs of inflammation, a dense hyperreflective band was noted in the stroma directly below the epithelium in the area of thinning, suggestive of scarring and/or cellular infiltration. | 27631347 |
| Inflammation, Fibrosis Assessment, Hemorrhage | Altered Intercellular Communication | We interpreted these displaced small nests to be the result of mechanical implantation occurring during the ureteroscopic procedure on the basis of the finding of associated linear fibrosis, inflammation, hemorrhage, and foreign body giant cells. | 27631511 |
| Inflammation | Altered Intercellular Communication | Apart from individual effects of structural damage or inflammation, genetic factors are suggested to influence HP. | 27631659 |
| Communicable Diseases | Altered Intercellular Communication | Inflammation-related anorexic response has been observed in systemic diseases as well as in localized infection and is an important issue in patient care. | 27631979 |
| Myeloid | Altered Intercellular Communication | We show that in infected mice, splenic extramedullary erythropoiesis could compensate for the chronic low-grade type I inflammation-induced phagocytosis of senescent red blood cells (RBCs) in spleen and liver myeloid cells, as well as for the impaired maturation of RBCs occurring in the bone marrow and spleen. | 27632207 |
| Inflammation, Liver damage, Hypoxia | Altered Intercellular Communication | In the intratracheal lipopolysaccharide model, 1,500 IU of intraperitoneal cholecalciferol treatment 6 hours postinjury reduced alveolar inflammation, cellular damage, and hypoxia. | 27632669 |
| Sepsis | Altered Intercellular Communication | Sepsis Pathophysiology, Chronic Critical Illness, and Persistent Inflammation-Immunosuppression and Catabolism Syndrome. | 27632674 |
| Sepsis | Altered Intercellular Communication | Once thought to be predominantly a syndrome of over exuberant inflammation, sepsis is now recognized as a syndrome of aberrant host protective immunity. | 27632674 |
| Inflammation | Altered Intercellular Communication | Patients with chronic critical illness often exhibit "a persistent inflammation-immunosuppression and catabolism syndrome," and it is proposed here that this state of persisting inflammation, immunosuppression and catabolism contributes to many of these adverse clinical outcomes. | 27632674 |
| septic | Altered Intercellular Communication | Although newer therapeutic interventions are targeting the inflammatory, the immunosuppressive, and the protein catabolic responses individually, successful treatment of the septic patient with chronic critical illness and persistent inflammation-immunosuppression and catabolism syndrome may require a more complementary approach. | 27632674 |
| Inflammation | Altered Intercellular Communication | The physical stress placed on the tendon results in microtrauma, which leads to subsequent inflammation and degeneration. | 27632817 |
| Inflammation, Corneal Endothelial Cell Loss | Altered Intercellular Communication | Markers of endothelial damage, inflammation, and cellular aging were completely attenuated by red wine consumption. | 27633722 |
| Inflammation, Corneal Endothelial Cell Loss | Altered Intercellular Communication | Cigarette smoke results in acute endothelial damage, vascular and systemic inflammation, and indicators of the cellular aging processes in otherwise healthy nonsmokers. | 27633722 |
| Inflammation | Altered Intercellular Communication | Periostin, an extracellular matrix protein produced by fibroblasts, induces chronic inflammation by stimulating TSLP production. | 27634769 |
| Inflammation | Altered Intercellular Communication | No participants had clinical evidence of joint inflammation at the time of scanning. | 27635596 |
| Inflammation, Hyperuricemia | Altered Intercellular Communication | Although individuals with asymptomatic hyperuricemia lack ultrasound features of inflammation or structural joint changes, they demonstrate a similar frequency of urate deposition. | 27635596 |
| Inflammation | Altered Intercellular Communication | Poor psychological well-being and increased serum cytokine levels, but not colonic low-grade inflammation, were associated with IBS-like symptoms. | 27636379 |
| Inflammatory Bowel Diseases, Inflammation | Altered Intercellular Communication | Inflammatory bowel disease (IBD) is characterized by a chronic inflammation of the gut, partly driven by defects in the expression and function of pattern recognition receptors, including the IFI16 protein. | 27636380 |
| Data types - Address, physiopathological | Altered Intercellular Communication | We hypothesize that such changes may result in disturbed cellular clearance and a perturbed cell-to-cell communication that may contribute to neuronal dysfunction and cell death in AD. | 27636840 |
| Inflammation, Malignant neoplasm of gastrointestinal tract, Neoplasms | Altered Intercellular Communication | Several NADPH oxidase family members, including dual oxidase 2 [DUOX2], are expressed in human tumors, particularly gastrointestinal cancers associated with long-standing chronic inflammation. | 27637085 |
| Cessation of life, Sepsis, Multiple Organ Failure, Inflammation | Altered Intercellular Communication | Death from sepsis in the intensive therapy unit (ITU) is frequently preceded by the development of multiple organ failure as a result of uncontrolled inflammation. | 27637335 |
| Inflammation, Cartilage damage, BDI - Functional Impairment, Erosion of bone, Arthritis | Altered Intercellular Communication | Cartilage damage and bone erosion are more prominent determinants of functional impairment in longstanding experimental arthritis than synovial inflammation. | 27638666 |
| Inflammation, Joints, Refractory anemias, Rheumatoid Arthritis, BDI - Functional Impairment | Altered Intercellular Communication | Chronic inflammation of articular joints causing bone and cartilage destruction consequently leads to functional impairment or loss of mobility in affected joints from individuals affected by rheumatoid arthritis (RA). | 27638666 |
| Inflammation, Cartilage damage, Refractory anemias, Tumor necrosis, BDI - Functional Impairment, Acute and chronic inflammation, Erosion of bone | Altered Intercellular Communication | In this context, we investigated the impact of the distinct components, including synovial inflammation, bone erosion or cartilage damage, as well as the effect of blocking tumor necrosis factor (TNF) on functional impairment in human-TNF transgenic (hTNFtg) mice, a chronic inflammatory erosive animal model of RA. | 27638666 |
| Erosion lesion, Cartilage damage, Synovitis | Altered Intercellular Communication | By investigating the association of gait parameters with inflammation-mediated joint pathologies at different time points of the disease course, we found a relationship between gait parameters and the extent of cartilage damage and bone erosions, but not with the extent of synovitis in this chronic model. | 27638666 |
| Inflammation | Altered Intercellular Communication | However, blocking TNF did not restore full functionality owing to remaining subclinical inflammation and structural microdamage. | 27638666 |
| Inflammation, Cartilage damage, BDI - Functional Impairment, Erosion of bone, Arthritis | Altered Intercellular Communication | Our findings indicate that cartilage damage and bone erosion, but not synovial inflammation, are the most important determinants for progressive functional impairment in this chronic erosive arthritis model. | 27638666 |
| Inflammation | Altered Intercellular Communication | Recent longitudinal work suggests that weight change is an important risk factor for inflammation across the full range of BMI. | 27638785 |
| Weight Gain, Inflammation | Altered Intercellular Communication | However, few studies have examined whether the risk of inflammation differs by patterns of weight gain over time. | 27638785 |
| Weight Gain, Inflammation, Metabolic Diseases | Altered Intercellular Communication | These results suggest that trajectories of weight gain are an important clinical concern and may identify those at risk for inflammation and the development of cardiometabolic disease. | 27638785 |
| Inflammation | Altered Intercellular Communication | 18F-FDG positron emission tomography (PET) can identify plaque inflammation as a surrogate endpoint for vascular interventional drug trials. | 27639759 |
| Coronary Arteriosclerosis | Altered Intercellular Communication | (Vascular Inflammation in Patients at Risk for Atherosclerotic Disease; NTR5006). | 27639759 |
| Dysplasia, Gastrointestinal inflammation | Altered Intercellular Communication | Fx-/- mice receiving control bone marrow cells had intestinal inflammation and dysplasia, and reduced expression of cytokines produced by cytotoxic T cells. | 27639802 |
| Colitis | Altered Intercellular Communication | Mini-endoscopic images revealed that hgd40 and anti-TNF reduced colon inflammation over 3 days; hgd40 reduced colitis in TNFR double-knockout mice. | 27639807 |
| Inflammation, Aortic Valve Stenosis | Altered Intercellular Communication | Aortic valve stenosis is characterized by inflammation and extracellular matrix remodelling. | 27643581 |
| Inflammation, Prostate carcinoma, Benign prostatic hypertrophy, Structure of posterior cerebral artery | Altered Intercellular Communication | The human papilloma viruses (HPVs) are a family of sexually transmitted viruses which have may have roles in the etiology of inflammation in the prostate leading to benign prostatic hyperplasia (BPH) and prostate cancer (PCa). | 27644644 |
| Cessation of life, Communicable Diseases, Inflammation | Altered Intercellular Communication | We identified numerous proteins that provide evidence of activation of the innate immunity system in two of the mummies, one of which also contained proteins indicating severe tissue inflammation, possibly indicative of an infection that we can speculate may have been related to the cause of death.This article is part of the themed issue 'Quantitative mass spectrometry'. | 27644972 |
| Inflammation, Autoimmune Disorder, CTCAE | Altered Intercellular Communication | Multiple Sclerosis (MS) is an autoimmune disorder leading to central nervous system inflammation. | 27645349 |
| Autoimmune Diseases, Sarcoidosis, Myelitis, Lupus Erythematosus | Altered Intercellular Communication | According to the new extended definition, NMOSD is closely associated with extensive spinal cord inflammation occurring in the course of systemic autoimmune diseases as sarcoidosis or lupus erythematodes. | 27645353 |
| Inflammatory Bowel Diseases, Inflammation | Altered Intercellular Communication | A subset of patients with inflammatory bowel diseases (IBD) have continuously active inflammation, leading to a high number of complications and high direct health care costs (diagnostic tests, medications, and surgeries) and indirect costs (reduced employment and productivity and fewer opportunities for activities). | 27645518 |
| Inflammation, Malnutrition, Chronic Kidney Diseases | Altered Intercellular Communication | Associations among Serum Beta 2 Microglobulin, Malnutrition, Inflammation, and Advanced Cardiovascular Event in Patients with Chronic Kidney Disease. | 27645611 |
| Inflammation, Malnutrition, Chronic Kidney Diseases, Atherosclerosis | Altered Intercellular Communication | This study examines the associations among serum b2 microglobulin (B2M), malnutrition, inflammation, and atherosclerosis (MIA) in those with chronic kidney disease (CKD). | 27645611 |
| Inflammation, Neuralgia, Pain Distress Question | Altered Intercellular Communication | Recent data provided proof that neuropathic pain patients exhibit increased numbers of immunosuppressive regulatory T cells (Tregs), which may represent an endogenous attempt to limit inflammation and to reduce pain levels. | 27646435 |
| Inflammation, Neuralgia | Altered Intercellular Communication | Our findings suggest that in neuropathic pain, enhanced targeting of SIRT1 by miR-124a and miR-155 induces a bias of CD4(+) T cell differentiation towards Tregs, thereby limiting pain-evoking inflammation. | 27646435 |
| Carcinoma of lung | Altered Intercellular Communication | Significance of coexistent granulomatous inflammation and lung cancer. | 27646525 |
| Granulomatous inflammation | Altered Intercellular Communication | Coexistence of lung cancer and granulomatous inflammation in the same patient confuses clinicians. | 27646525 |
| Necrotizing granulomatous inflammation, Primary malignant neoplasm | Altered Intercellular Communication | One hundred and twenty-seven patients underwent lung resection for cancer, out of which 19 (14.9%) had coexistent granulomatous inflammation in the resected specimen. | 27646525 |
| Granulomatous inflammation, Primary malignant neoplasm | Altered Intercellular Communication | Incidental detection of granulomatous inflammation in patients undergoing lung resection for cancer, even in a TB-endemic country, may not require any intervention. | 27646525 |
| Airway structure, Sleep-Disordered Breathing, Signs and Symptoms, Respiratory | Altered Intercellular Communication | We aimed to investigate the association between nGER and respiratory symptoms, exacerbations of respiratory symptoms, SDB and airway inflammation. | 27646537 |
| Inflammation | Altered Intercellular Communication | In patients with NMIBC, markers of systemic inflammation response are associated with disease recurrence and progression. | 27646875 |
| Inflammation, Pain Distress Question | Altered Intercellular Communication | SPECT-CT showed increased radiotracer uptake and inflammation at the level of pain generation indicated by history and physical examination. | 27647036 |
| Intraocular inflammation, Endophthalmitis, CTCAE, Traumatic injury | Altered Intercellular Communication | Endophthalmitis is potentially devastating intraocular inflammation following eye trauma or surgery. | 27647122 |
| Diabetic Nephropathy, Inflammation | Altered Intercellular Communication | The effects of selenium supplementation on biomarkers of inflammation and oxidative stress in patients with diabetic nephropathy: a randomised, double-blind, placebo-controlled trial. | 27647263 |
| Inflammation | Altered Intercellular Communication | Osteopontin (OPN) is an essential cytokine involved in immune cell recruitment and an important regulator of inflammation. | 27647996 |
| Inflammation, Prostate carcinoma | Altered Intercellular Communication | Backgroud: Increasing evidence suggests the involvement of chronic inflammation in the progression of prostate cancer, and prostaglandin-endoperoxide synthase 2 (PTGS2), also known as cyclooxygenase-2, catalyzes the rate-limiting steps of the pathway. | 27647999 |
| Inflammation, Calcification of coronary artery, Rheumatoid Arthritis | Altered Intercellular Communication | Coronary Artery Calcification Is Related to Inflammation in Rheumatoid Arthritis: A Long-Term Follow-Up Study. | 27648442 |
| Refractory anemias, Inflammation, SLC25A20 gene | Altered Intercellular Communication | CAC is related to inflammation in patients with RA. | 27648442 |
| Communicable Diseases, Inflammation | Altered Intercellular Communication | Distinction between inflammation secondary to surgery, especially coronary artery bypass graft with cardiopulmonary bypass (CPB), and inflammation due to infection is difficult in surgical intensive care unit (ICU) patients. | 27648690 |
| Communicable Diseases, Inflammation | Altered Intercellular Communication | In conclusion, CD64 index only in combination with CRP concentrations could be used to discriminate inflammation due to surgery from that due to infection in this particular population. | 27648690 |
| Inflammation, Lymphoma | Altered Intercellular Communication | Lymphoma and inflammation in the orbit: Diagnostic performance with diffusion-weighted imaging and dynamic contrast-enhanced MRI. | 27649521 |
| Orbital lymphoma, Orbital Pseudotumor | Altered Intercellular Communication | Parameters of DWI and DCE MRI were evaluated in these 30 patients with orbital lymphoma and 23 patients with orbital inflammation. | 27649521 |
| Orbital lymphoma, Orbital Pseudotumor | Altered Intercellular Communication | The combination of both was significantly superior to DWI for differentiation of orbital lymphoma from orbital inflammation (P = 0.016 for reviewer 1; P = 0.001 for reviewer 2). | 27649521 |
| Inflammation, Lymphoma | Altered Intercellular Communication | The combination of DWI and DCE MRI can improve diagnostic performance in differentiating lymphoma from inflammation in the orbit compared with DWI alone. | 27649521 |
| Inflammation, Atrophic, Adenocarcinoma of prostate | Altered Intercellular Communication | Inflammation and focal atrophy in prostate needle biopsy cores and association to prostatic adenocarcinoma. | 27649956 |
| Proliferative Inflammatory Atrophy, Inflammation, Traumatic injury, Adenocarcinoma of prostate | Altered Intercellular Communication | The possible origin of proliferative inflammatory atrophy in the regenerative proliferation of prostate epithelial cells in response to injury caused by inflammation, and their relation to prostate adenocarcinoma have not been defined. | 27649956 |
| Inflammation, Atrophic | Altered Intercellular Communication | Inflammation and focal atrophy are common pathological findings in prostate biopsies, currently not routinely included in surgical pathology reports. | 27649956 |
| Inflammation, Focal atrophy, Adenocarcinoma, Malignant Neoplasms, Intraepithelial Neoplasia | Altered Intercellular Communication | Prostate needle biopsies from 203 patients with clinical parameters suspicious for malignancy were evaluated for the presence and extent of chronic inflammation, type and grade of focal atrophy, high-grade intraepithelial neoplasia, and adenocarcinoma. | 27649956 |
| Adenocarcinoma, Inflammation | Altered Intercellular Communication | Chronic inflammation was observed in 77.3% of the biopsies, significantly associated to adenocarcinoma (P = .031). | 27649956 |
| Inflammation, Adenocarcinoma of prostate | Altered Intercellular Communication | Moderate/severe inflammation in at least 1 biopsy core increased the risk of prostate adenocarcinoma (odds ratio, 2.94; 95% confidence interval, 1.27-6.8), whereas glandular localization of inflammation decreased the risk. | 27649956 |
| Proliferative Inflammatory Atrophy, Inflammation, Atrophic | Altered Intercellular Communication | Focal atrophy was present in 72.9% of the biopsies, proliferative inflammatory atrophy was the most common type, and its grade was significantly associated to inflammation (P < .0001) and inflammation intensity (P = .003). | 27649956 |
| Adenocarcinoma of prostate, Inflammation | Altered Intercellular Communication | An association between prostate adenocarcinoma and inflammation was found, with higher odds in presence of moderate/severe inflammation in at least 1 biopsy core. | 27649956 |
| Proliferative Inflammatory Atrophy, Inflammation | Altered Intercellular Communication | Increasing grades of proliferative inflammatory atrophy were associated to high levels of inflammation, supporting its previously proposed inflammatory nature. | 27649956 |
| Chronic Infantile Neurological, Cutaneous, and Articular Syndrome, NLRP3 gene, Chronic Urticaria | Altered Intercellular Communication | This is despite almost all MWS patients having family members with similar symptoms and children with NOMID presenting with chronic infantile urticaria associated with multi-system inflammation. | 27650144 |
| Chronic Infantile Neurological, Cutaneous, and Articular Syndrome, Familial cold urticaria, NLRP3 gene, Muckle-Wells Syndrome | Altered Intercellular Communication | Cryopyrin-associated periodic syndromes (CAPS) encapsulate three auto-inflammatory conditions, ranging in severity from mild (familial cold auto-inflammatory syndrome: FCAS), moderate (Muckle-Wells syndrome: MWS) and severe (neonatal onset multi-inflammatory disorder: NOMID). | 27650144 |
| Atherosclerosis of renal artery, HLA Class IA Histocompatibility Antigen Measurement, Cerebrovascular accident | Altered Intercellular Communication | Inflammation comprises important aspects of large-artery atherosclerosis (LAA) stroke pathophysiology. | 27650381 |
| Inflammation, Aortic Aneurysm, Abdominal | Altered Intercellular Communication | Age-Associated Sirtuin 1 Reduction in Vascular Smooth Muscle Links Vascular Senescence and Inflammation to Abdominal Aortic Aneurysm. | 27650558 |
| Old age, Inflammation | Altered Intercellular Communication | In this study, we investigated the role of SIRT1 (Sirtuin 1), a class III histone deacetylase, in AAA formation and the underlying mechanisms linking vascular senescence and inflammation. | 27650558 |
| vascular inflammations | Altered Intercellular Communication | Mechanistically, the reduction of SIRT1 was shown to increase vascular cell senescence and upregulate p21 expression, as well as enhance vascular inflammation. | 27650558 |
| Inflammation, Glucocorticoid deficiency with achalasia, Muscle, Smooth, Vascular | Altered Intercellular Communication | These findings provide evidence that SIRT1 reduction links vascular senescence and inflammation to AAAs and that SIRT1 in vascular smooth muscle cells provides a therapeutic target for the prevention of AAA formation. | 27650558 |
| Pancreatic carcinoma | Altered Intercellular Communication | Prognostic Value of the CRP/Alb Ratio, a Novel Inflammation-Based Score in Pancreatic Cancer. | 27650825 |
| Primary malignant neoplasm | Altered Intercellular Communication | However, as an inflammation-based score, its prognostic value for cancer has scarcely been investigated. | 27650825 |
| Inflammation, Dental Plaque | Altered Intercellular Communication | Repeated carotid measurements showed that inflammation was involved in novel plaque formation, while HDL-C was protective. | 27650831 |
| Hypertension, CTCAE | Altered Intercellular Communication | In addition, it was demonstrated in animal models that TREGs may prevent angiotensin II-induced hypertension and vascular injury/inflammation. | 27653031 |
| Laryngitis | Altered Intercellular Communication | Our findings indicate that laryngeal inflammation is not directly mediated by loss of Treg cells in response to smoking and reflux in local tissue and increased ImmunoCRIT values in smokers implicate a role for this environmental exposure in modulating laryngeal immune homeostasis. | 27653511 |
| Pneumonitis | Altered Intercellular Communication | Atherogenic high cholesterol/high fat diet induces TLRs-associated pulmonary inflammation in C57BL/6J mice. | 27653962 |
| Hypercholesterolemia, Pneumonitis | Altered Intercellular Communication | These findings suggested that high cholesterol/high fat diet-induced hypercholesterolemia could result in TLRs/NFkB pathway-associated low-grade pulmonary inflammation in C57BL/6J mice, which might alter the lung's immune responsiveness to a variety of environmental exposures. | 27653962 |
| Acute inflammation | Altered Intercellular Communication | Comparison of the safety and efficacy of single injection of subtenon triamcinolone and topical dexamethasone in reducing postoperative inflammation after phacoemulsification and intraocular lens implantation. | 27654733 |
| Inflammation, Folliculitis | Altered Intercellular Communication | Folliculitis is defined as the inflammation of the follicles. | 27655127 |
| Inflammation, Malnutrition | Altered Intercellular Communication | Mortality in children with complicated severe acute malnutrition is related to intestinal and systemic inflammation: an observational cohort study. | 27655441 |
| Diarrhea, Gastrointestinal inflammation | Altered Intercellular Communication | We investigated diarrhea, enteropathogens, and systemic and intestinal inflammation for their interrelation and their associations with mortality in children with SAM. | 27655441 |
| Cessation of life, Inflammation, Diarrhea | Altered Intercellular Communication | Mortality was directly related to high systemic inflammation (path coefficient = 0.49), whereas diarrhea, high calprotectin, and low SCFA production related to death indirectly via their more direct association with systemic inflammation. | 27655441 |
| Inflammation, Diarrhea, Gastrointestinal inflammation | Altered Intercellular Communication | Diarrhea, high intestinal inflammation, low concentrations of fecal SCFAs, and high systemic inflammation are significantly related to mortality in SAM. | 27655441 |
| Inflammation, Blood Clot, Kidney Failure, Acute | Altered Intercellular Communication | Excessive platelet activation contributes to AKI through the formation of microthrombi and amplification of systemic inflammation. | 27656709 |
| Airway structure | Altered Intercellular Communication | However, the two groups did not differ in airway inflammation, which indicated that a synergistic effect of the LABA on enhancing the anti-inflammatory action of the ICS was not clinically apparent. | 27657522 |
| Inflammation, Airway structure, Smoking, Obstruction, Obesity | Altered Intercellular Communication | Smoking, obesity, physical inactivity, airway inflammation and obstruction, and adipose tissue and inflammatory marker activation are related in systemic inflammation. | 27658459 |
| Inflammation, Schizophrenia | Altered Intercellular Communication | Low-grade inflammation is also associated with schizophrenia. | 27658459 |
| Inflammation, Schizophrenia | Altered Intercellular Communication | Resistin is a biomarker of systemic inflammation associated with smoking among patients with schizophrenia on clozapine treatment. | 27658459 |
| Inflammation, Impaired cognition | Altered Intercellular Communication | Body mass and cognitive decline are indirectly associated via inflammation among aging adults. | 27658542 |
| Inflammation, Impaired cognition, Nerve Degeneration | Altered Intercellular Communication | Inflammatory models of neurodegeneration suggest that higher circulating levels of inflammation can lead to cognitive decline. | 27658542 |
| Inflammation, Impaired cognition | Altered Intercellular Communication | Despite established independent associations between greater body mass, increased inflammation, and cognitive decline, no prior research has explored whether markers of systemic inflammation might mediate the association between body mass and changes in cognitive functioning. | 27658542 |
| Inflammation | Altered Intercellular Communication | Our results suggest that systemic inflammation is one biologically plausible mechanism through which differences in body mass might influence changes in cognitive functioning among aging adults. | 27658542 |
| Inflammation, Calcified (qualifier), Traumatic injury, Vascular lesions | Altered Intercellular Communication | Inflammation, trauma, debris acting as nidus and vascular lesions have been attributed as principal causes for occurrence of calcifications within the oral mucosa. | 27659092 |
| Refractory anemias, Inflammation, Rheumatoid Arthritis, Osteoporosis | Altered Intercellular Communication | This study aimed to investigate the efficacy of denosumab (compared with that of bisphosphonates) for preventing secondary osteoporosis and inflammation caused by excessive bone resorption in Japanese rheumatoid arthritis (RA) patients never previously treated for osteoporosis. | 27659808 |
| Refractory anemias, Inflammation, Osteoporosis | Altered Intercellular Communication | Neither denosumab nor bisphosphonates could suppress inflammation or RA disease activity, but denosumab significantly suppressed a marker of bone metabolism in Japanese RA patients never previously treated for osteoporosis. | 27659808 |
| Inflammation | Altered Intercellular Communication | Pentraxin 3 (PTX3), an essential component of the innate immunity system that plays a non-redundant role in controlling inflammation, regulates complement by interacting with complement components. | 27659908 |
| Inflammation, Diabetes Mellitus | Altered Intercellular Communication | The goal was to identify active compounds in hot aqueous extracts of BL (HAE-BL) that are consistent with a role in reducing inflammation and reducing the vascular pathology associated with diabetes. | 27660013 |
| Inflammation, Blood Vessel | Altered Intercellular Communication | All of these properties are consistent with a role in reducing inflammation and reducing vascular leak. | 27660013 |
| Inflammation, Liver damage, Acute-On-Chronic Liver Failure | Altered Intercellular Communication | Patients with HBV-related acute-on-chronic liver failure have increased concentrations of extracellular histones aggravating cellular damage and systemic inflammation. | 27660136 |
| Inflammation, Hepatitis B, Chronic, CRNKL1 wt Allele, Liver Cirrhosis | Altered Intercellular Communication | We found that plasma histone H4 levels were greatly increased in patients with ACLF as compared with chronic hepatitis B, liver cirrhosis and healthy control subjects and were significantly associated with disease severity, systemic inflammation and outcome. | 27660136 |
| Inflammation, Liver damage, CRNKL1 wt Allele | Altered Intercellular Communication | The data support the hypothesis that the increased extracellular histone levels in ACLF patients may aggravate disease severity by inducing cellular injury and systemic inflammation. | 27660136 |
| cell injury | Altered Intercellular Communication | Recently, extracellular histones, especially H4, have been recognized as important mediators of cell damage in various inflammatory conditions. | 27660136 |
| Extrinsic allergic alveolitis, Pneumonia, Granulomatous inflammation, Drug toxicity, Sarcoidosis | Altered Intercellular Communication | The most frequent histopathologic patterns were granulomatous inflammation (12 patients) and organizing pneumonia (OP) (11 patients), resulting in the final diagnoses of hypersensitivity pneumonitis (six patients), cryptogenic OP (six patients), connective tissue disease-associated OP (three patients), drug toxicity (three patients), infection-related OP (two patients), sarcoidosis (two patients), and aspiration (one patient). | 27660154 |
| Malignant neoplasm of urinary bladder, Inflammation, Aggressive behavior | Altered Intercellular Communication | We speculated that a heterogeneous population of non-muscle invasive bladder cancer (NMIBC) patients with a previous history of smoking may be more precisely stratified by a biomarker associated with tumor aggressiveness and then focused on the preoperative neutrophil-to-lymphocyte ratio (pre-NLR), which is a simple index of systemic inflammation. | 27660257 |
| Inflammation, Chlamydia trachomatis, Pelvic adhesions | Altered Intercellular Communication | Elevated titers of anti-Chlamydia trachomatis antibodies are frequently associated with laparoscopic evidence of pelvic adhesions and inflammation. | 27660878 |
| Degenerative polyarthritis, Inflammation | Altered Intercellular Communication | The identification of calcium crystals in synovial fluid (SF) of patients with osteoarthritis (OA) represents an important step in understanding the role of these crystals in synovial inflammation and disease progression. | 27660935 |
| Inflammation, Primary malignant neoplasm | Altered Intercellular Communication | The PTEN/Akt pathway is a plausible candidate as it may play a role in mediating inflammation via COX-2, and has been associated with cancer progression. | 27661110 |
| Communicable Diseases, Necrotizing fasciitis, Inflammation, Necrosis | Altered Intercellular Communication | Necrotizing fasciitis is an infection of the soft tissue that is characterized by rapidly spreading inflammation and subsequent necrosis. | 27662064 |
| Inflammation | Altered Intercellular Communication | Our findings suggest that TREM2 not only plays a critical role in inflammation, but is also involved in neuronal cell survival and in neurogenesis. | 27662313 |
| Neurodegenerative Disorders, Inflammation | Altered Intercellular Communication | As inflammation plays a major role in neurodegenerative diseases, a lack of TREM2 could be a missing link between immunomodulation and neuroprotection. | 27662313 |
| Inflammation, "Alzheimers Disease", Amyloidosis | Altered Intercellular Communication | Acceleration of Amyloidosis by Inflammation in the Amyloid-Beta Marmoset Monkey Model of Alzheimer's Disease. | 27662314 |
| Inflammation | Altered Intercellular Communication | The effect of inflammation on amyloidopathy was also investigated in an additional monkey that suffered from chronic inflammatory wasting syndrome. | 27662314 |
| Inflammation | Altered Intercellular Communication | Two out of three monkeys injected with Ab and LPS and the additional monkey, suffering from chronic inflammation, developed plaques. | 27662314 |
| Inflammation, Scleritis, Surgical reduction | Altered Intercellular Communication | The primary outcome was at least a 2-step reduction or reduction to grade 0 in scleral inflammation on a 0 to +4 scale according to a standardized photographic scleritis grading system by 16 weeks in the study eye compared to baseline. | 27663070 |
| Inflammation, Deep thrombophlebitis | Altered Intercellular Communication | These findings favor the hypothesis that inflammation is a cause and not merely a consequence of acute DVT. | 27663463 |
| Inflammation, Psoriasis | Altered Intercellular Communication | The evidence that psoriasis is associated with systemic inflammation and significantly higher incidence of cardiovascular risk factors has already been described. | 27663919 |
| Inflammation, Glioblastoma Multiforme Pathway | Altered Intercellular Communication | Our findings suggest that radiation induces a rapid enhancement of the prevailing inflammation in high-grade glioma tissue. | 27664151 |
| Inflammation, Stomach Carcinoma, Neoplasms | Altered Intercellular Communication | Systemic inflammation is associated with the density of immune cells in the tumor microenvironment of gastric cancer. | 27665104 |
| Inflammation, Malignant Neoplasms | Altered Intercellular Communication | The neutrophil-lymphocyte ratio (NLR) and the prognostic nutritional index (PNI) are markers of systemic inflammation known to be useful prognostic indicators of malignancy. | 27665104 |
| Inflammation, Neoplasms | Altered Intercellular Communication | However, little evidence has defined the influence of inflammation on the tumor microenvironment. | 27665104 |
| Inflammation, Stomach Carcinoma, Neoplasms | Altered Intercellular Communication | The NLR and PNI are associated with the density of CD4+ immune cells in the tumor microenvironment, which leads to prognostic values of systemic inflammation in gastric cancer. | 27665104 |
| Pancreatic carcinoma | Altered Intercellular Communication | The combination of systemic inflammation-based marker NLR and circulating regulatory T cells predicts the prognosis of resectable pancreatic cancer patients. | 27665172 |
| Inflammation, Neoplasms, Pancreatic carcinoma, Impaired | Altered Intercellular Communication | The systemic inflammation response and immune impairment are closely related to the development and progression of various tumours, such as pancreatic cancer. | 27665172 |
| Inflammation, Dryness (characteristic) | Altered Intercellular Communication | Thus, the MMP-9 results indicated a clinically significant inflammation in 40% of dry eye patients. | 27665213 |
| Dryness (characteristic), Inflammatory abnormality of the eye, Dryness of eye | Altered Intercellular Communication | It correlated well with other dry eye tests and identified the presence of ocular surface inflammation in 40% of confirmed dry eye patients. | 27665213 |
| Autoimmune Diseases, Inflammatory abnormality of the eye | Altered Intercellular Communication | It may be especially helpful to identify patients with ocular surface inflammation and autoimmune disease and may facilitate the decision to institute anti-inflammatory treatment in these patients. | 27665213 |
| Inflammation, Disorder of mineral metabolism, Endothelial dysfunction, Ventricular Dysfunction, Chronic Kidney Diseases | Altered Intercellular Communication | CKD can contribute to the development and progression of right ventricle dysfunction with endothelial dysfunction, inflammation and mineral metabolism disorders. | 27665506 |
| Inflammation, Vascular System Injuries | Altered Intercellular Communication | CXCL16 is both a cholesterol receptor and a chemokine with a potential role in vascular injury and inflammation. | 27665581 |
| Communicable Diseases, Inflammation | Altered Intercellular Communication | It should not be reported as a pathological finding on MRI unless clinical findings support regional infection or inflammation. | 27666183 |
| HD Term Type, Inflammation, Obesity | Altered Intercellular Communication | Obesity is becoming increasingly common in hemodialysis (HD) patients and is associated with inflammation and increased mortality. | 27666944 |
| Inflammation, Atherosclerosis | Altered Intercellular Communication | Many studies have revealed a role of YKL-40 as a new inflammatory biomarker in angiogenesis, inflammation, atherosclerosis and cardiovascular events. | 27668705 |
| Communicable Diseases, Inflammation | Altered Intercellular Communication | No pathologic evidence was seen of microorganisms, acute or chronic inflammation, or infection. | 27669046 |
| Inflammation | Altered Intercellular Communication | Our data revealed that the variation in Th1, Th17, CXCL16 and homocysteine in peripheral blood of patients with stenting may be implicated in inflammation after intracranial and cervical stent implantation. | 27669631 |
| Inflammation | Altered Intercellular Communication | It is mostly difficult to determine the causative agent that causes inflammation in the joints. | 27671189 |
| Inflammation, Primary malignant neoplasm | Altered Intercellular Communication | Regulatory T Cells (Tregs) and Myeloid-Derived Suppressor Cells (MDSCs) are two main regulatory cells modulating the immune responses in inflammation and cancer. | 27671508 |
| Inflammation | Altered Intercellular Communication | MSC-SKL-GFP attenuated monocrotaline-induced inflammation, as evidenced by decreased macrophage infiltration around PAs. | 27672025 |
| Inflammation | Altered Intercellular Communication | SKL attenuates monocrotaline-induced PA remodeling and PA smooth muscle cell proliferation, likely by reducing inflammation and restoring SIRT1 levels and eNOS activity. | 27672025 |
| Inflammation, Traumatic, Spinal Cord Injuries, Stanford Cancer Institute | Altered Intercellular Communication | Inflammation in traumatic spinal cord injury (SCI) has been proposed to promote damage acutely and oppose functional recovery chronically. | 27673428 |
| Inflammation, Stanford Cancer Institute | Altered Intercellular Communication | However, we do not yet understand the signals that initiate or prolong inflammation in persons with SCI. | 27673428 |
| Inflammation, Stanford Cancer Institute | Altered Intercellular Communication | Together, these data suggest that HMGB1 may be a common, early, and persistent danger signal promoting inflammation in individuals with SCI. | 27673428 |
| Inflammation | Altered Intercellular Communication | Highly suggestive cyst wall features are an acellular hyaline lining surrounded by focally calcific fibrous tissue and chronic inflammation. | 27673549 |
| Stable chronic Graft vs Host Disease, Inflammation, Fibrosis Assessment, Chronic graft-versus-host disease | Altered Intercellular Communication | Chronic graft-versus-host disease (cGvHD), characterized by inflammation and fibrosis of multiple target organs, considerably contributes to the morbidity and mortality even years after allo-HSCT. | 27677743 |
| Inflammation, MTA2 gene, Infertility, Salpingitis, Pelvic Inflammatory Disease | Altered Intercellular Communication | Pelvic inflammatory disease (PID) and more specifically salpingitis (visually confirmed inflammation) is the primary cause of tubal factor infertility and is an important risk factor for ectopic pregnancy. | 27678278 |
| Inflammation, Fibrosis Assessment, Fatty degeneration | Altered Intercellular Communication | The results showed a clear association between severe liver pathological conditions (inflammation, steatosis and fibrosis) and (GA + AA) genotypes (P = 0.035, 0.03, 0.04 respectively). | 27678360 |
| Fibrosis Assessment, Fatty degeneration, Hepatitis | Altered Intercellular Communication | The stepwise logistic regression analysis showed that the TNFa genotypes (GA + AA) were significantly associated with liver inflammation (OR = 3.776, 95%CI: 1.399-10.194, P = 0.009), severe steatosis (OR = 4.49, 95%CI: 1.441-14.0, P = 0.010) and fibrosis progression (OR = 2.84, 95%CI: 1.080-7.472, P = 0.034). | 27678360 |
| Fibrosis Assessment, Fatty degeneration, Hepatitis | Altered Intercellular Communication | Also, the A allele was an independent risk factor for liver inflammation (P = 0.003), steatosis (P = 0.003) and fibrosis (P = 0.014). | 27678360 |
| Inflammation, Complication Aspects | Altered Intercellular Communication | Inflammation is one of the primary mechanisms in the development of metabolic complications. | 27678438 |
| Autoimmune Chronic Hepatitis, Hepatitis, Insemination, Artificial, Homologous | Altered Intercellular Communication | Autoimmune hepatitis (AIH) is characterised by liver inflammation with reversibility upon anti-inflammatory treatment. | 27679428 |
| Inflammation, Liver diseases, Insemination, Artificial, Homologous | Altered Intercellular Communication | Soluble (s)CD163, a specific macrophage activation marker, is associated with inflammation in other liver diseases, but never investigated in AIH. | 27679428 |
| Inflammation, Erythema | Altered Intercellular Communication | Keloid redness is due to angiogenesis and chronic inflammation and is an important indicator of the severity of the lesion and the effectiveness of treatment. | 27680482 |
| Inflammation, Peripheral Vascular Insufficiency, Blood Coagulation Disorders | Altered Intercellular Communication | Recently, serum lactate level rather than systolic blood pressure (sBP) has been widely used to diagnose peripheral circulatory insufficiency, which often leads to coagulopathy with systemic inflammation. | 27680483 |
| Inflammation, Takotsubo Cardiomyopathy | Altered Intercellular Communication | Systemic inflammation has been hypothesized as a possible mechanism of Takotsubo cardiomyopathy (TTC). | 27680775 |
| Vasculitis, Leukocytoclastic, Cutaneous, Inflammation, Cutaneous Small Vessel Vasculitis | Altered Intercellular Communication | Leukocytoclastic vasculitis (LCV) is a rare small-vessel vasculitis characterised by neutrophilic inflammation of post-capillary venules. | 27681337 |
| Inflammation, Tooth Loss | Altered Intercellular Communication | To examine the impact of tooth loss on walking speed over time and explore whether inflammation may account for this association. | 27682433 |
| Inflammation, Tooth Loss, Chronic disease, Behavior Disorders | Altered Intercellular Communication | Mixed-effects models showed that tooth loss was associated with a greater decline in walking speed over time after adjustment for lifestyle-related factors and chronic diseases (p = 0.001 for interaction between time and tooth loss on walking speed decline); however, when further adjusting for inflammation (CRP), the association was attenuated and no longer significant. | 27682433 |
| Inflammation, Tooth Loss | Altered Intercellular Communication | Inflammation may play a role in the association between tooth loss and walking speed decline. | 27682433 |
| Rheumatoid Arthritis, Inflammation | Altered Intercellular Communication | Investigation of a multi-biomarker disease activity score in rheumatoid arthritis by comparison with magnetic resonance imaging, computed tomography, ultrasonography, and radiography parameters of inflammation and damage. | 27682742 |
| Inflammation | Altered Intercellular Communication | In the 15 patients who had achieved a Disease Activity Score based on C-reactive protein (DAS28-CRP) < 2.6 at week 26, MRI and/or US detected subclinical inflammation and 13 (87%) had a moderate/high MBDA score. | 27682742 |
| Inflammation | Altered Intercellular Communication | In this cohort, the MBDA score correlated poorly with MRI/US inflammation. | 27682742 |
| Inflammation, Necrosis | Altered Intercellular Communication | However, the MBDA score and MRI/US were generally concordant in showing signs of inflammation in most patients in clinical remission during anti-tumour necrosis factor (anti-TNF) therapy. | 27682742 |
| Inflammation | Altered Intercellular Communication | Markers of inflammation and endothelial activation contributed significantly to CV events, but the limited number of events prevents further analysis. | 27682808 |
| Inflammation, Dental Plaque, Endothelial dysfunction, Atherosclerosis | Altered Intercellular Communication | The findings of the present study suggest that cigarette smoking may interfere with several essential parts of the atherosclerosis process, as evidenced by associations with protein markers representing endothelial dysfunction, inflammation, neointimal formation, foam cell formation and plaque instability. | 27684606 |
| Inflammation, Fibrosis Assessment, Vasculitis, CTCAE, Waldenstrom Macroglobulinemia | Altered Intercellular Communication | Histology suggested chronic inflammation in spinal dura mater with extensive fibrosis, dense lymphoplasmacytic infiltrate, and focal vasculitis. | 27684799 |
| Inflammation, Liver Failure, Acute, Liver damage | Altered Intercellular Communication | Circulating histones are major mediators of systemic inflammation and cellular injury in patients with acute liver failure. | 27685635 |
| Inflammation, GTF2A1L wt Allele, Injury of liver | Altered Intercellular Communication | Here we investigated the impact of circulating histones, recently identified inflammatory mediators, on systemic inflammation and liver injury in murine models and patients with ALF. | 27685635 |
| Inflammation, GTF2A1L wt Allele | Altered Intercellular Communication | Significant systemic inflammation was also pronounced in ALF patients, which were associated with histone levels. | 27685635 |
| Inflammation, Liver damage, Injury of liver | Altered Intercellular Communication | Heparin reduced systemic inflammation and liver damage in mice, suggesting that it could interfere with histone-associated liver injury. | 27685635 |
| Inflammation, GTF2A1L wt Allele, Liver damage | Altered Intercellular Communication | Collectively, these findings demonstrate that circulating histones are critical mediators of systemic inflammation and cellular damage in ALF, which may be potentially translatable for clinical use. | 27685635 |
| Compact Disk Interactive, Inflammation | Altered Intercellular Communication | CXCL13 is a well-known CXC chemokine involved in inflammation, but its role in CDI remains unknown. | 27685937 |
| Inflammation, Foot joint structure | Altered Intercellular Communication | Older age is associated with more MRI-detected inflammation in hand and foot joints. | 27686099 |
| Inflammation | Altered Intercellular Communication | Although MRI is recommended for diagnostic use in detecting joint inflammation, its value in clinical practice has not been settled. | 27686099 |
| Inflammation | Altered Intercellular Communication | Older symptom-free persons show more MRI-detected inflammation in their hands and feet. | 27686099 |
| Refractory anemias, Arthritis, Age of Onset | Altered Intercellular Communication | Because both effects could have diagnostic consequences, we evaluated the association between age-at-onset and MRI-detected inflammation in early arthritis and RA. | 27686099 |
| Synovitis, Inflammation, Tenosynovitis | Altered Intercellular Communication | Bone marrow oedema, synovitis and tenosynovitis were summed, yielding the MRI inflammation score. | 27686099 |
| Inflammation, Arthritis | Altered Intercellular Communication | Early arthritis and RA-patients had, respectively, 2.6 (95% CI: 2.3, 3.0, P < 0.001) and 3.7 times (95% CI: 3.2, 4.3, P < 0.001) higher MRI inflammation scores than controls (adjusted for age). | 27686099 |
| Refractory anemias, Inflammation, Arthritis | Altered Intercellular Communication | At higher age of onset, early arthritis and RA patients had higher MRI inflammation scores (1.03/year, P < 0.001). | 27686099 |
| Refractory anemias, Inflammation | Altered Intercellular Communication | At the joint level, older RA patients had more extended MRI inflammation, but the preferential locations were similar. | 27686099 |
| Arthritis | Altered Intercellular Communication | Older age is associated with more MRI-detected inflammation, and the effect was similar in arthritis and controls. | 27686099 |
| Inflammation, Swelling, With intensity | Altered Intercellular Communication | Spinal magnetic resonance imaging (MRI) revealed longitudinal hyperintensity with cord swelling and hypointensity on T2-weighted images, suggesting severe inflammation and microbleeding change, respectively. | 27686688 |
| Prurigo pigmentosa, Inflammation, Sycosis barbae | Altered Intercellular Communication | The frequent presence of bacterial colonies along with sequelae of inflammatory changes on biopsy provides new evidence to support the theory that prurigo pigmentosa is a reactive inflammation associated with bacterial folliculitis. | 27686778 |
| Inflammation, Colorectal Carcinoma | Altered Intercellular Communication | Inflammation plays an important role in the development and progression of CRC. | 27686880 |
| Inflammation, Fatigue, Endothelial dysfunction, Lupus Erythematosus, Systemic | Altered Intercellular Communication | Fatigue and cognitive function were assessed and related to SLE activity, clinical data and plasma biomarkers of inflammation and endothelial dysfunction. | 27687026 |
| Weight decreased, Pneumonitis | Altered Intercellular Communication | After challenged intranasally with RSV Long, the vaccinated mice showed both decreased lung RSV titers, pulmonary inflammation and body weight loss. | 27688078 |
| Inflammation, melanoma | Altered Intercellular Communication | IgG4-related intraocular inflammation masquerading as ciliary body melanoma in a young girl. | 27688285 |
| Barrett Esophagus, Inflammation, Adenocarcinoma Of Esophagus | Altered Intercellular Communication | Inflammation plays an important role in the development of esophageal adenocarcinoma and its metaplastic precursor lesion, Barrett's esophagus. | 27689189 |
| Carcinogenesis | Altered Intercellular Communication | Toll-like receptor (TLR) 2 signalling and lysosomal function have been linked to inflammation-associated carcinogenesis. | 27689189 |
| Avitaminosis, Neurotransmitters, "5-O-(4,4-dimethoxytrityl)thymidine-3-O-(2,4-dinitrophenyl) succinate | Altered Intercellular Communication | Hereditary dopamine transporter deficiency syndrome (DTDS) is a neurotransmitter disorder caused by a defect in the neuronal uptake of dopamine. | 27690368 |
| Biological Relative | Altered Intercellular Communication | Both patients had consanguineous parents and similar cerebrospinal fluid (CSF) neurotransmitter profiles with elevated homovanillic acid and increased the ratio of homovanillic acid to 5-hydroxyindoleacetic acid. | 27690368 |
| Muscle hypotonia, Oculogyric crisis, Infantile onset, Dystonia Disorders | Altered Intercellular Communication | Early infantile-onset progressive dystonia with oculogyric crises, hypotonia, developmental delay, and CSF neurotransmitter profile led to a diagnosis of DTDS in these two patients. | 27690368 |
| Inflammatory abnormality of the eye | Altered Intercellular Communication | Intravitreal sirolimus 440 mg demonstrated a significant improvement in ocular inflammation with preservation of BCVA in subjects with active NIU of the posterior segment. | 27692526 |
| Inflammation | Altered Intercellular Communication | Clinical evaluation included assessment of changes in visual acuity, degree of inflammation in the anterior chamber and vitreous cavity, central macular thickness, and retinal angiographic leakage. | 27692527 |
| Inflammation, Neoplasms | Altered Intercellular Communication | In recent years, the role of inflammation in the promotion of tumor growth is supported by a broad range of experimental and clinical evidence. | 27693669 |
| Bipolar, Pain Distress Question, Inflammation | Altered Intercellular Communication | Concordant pain could be triggered by touching the inflammation with the bipolar radiofrequency probe. | 27693825 |
| Inflammation, Granuloma | Altered Intercellular Communication | Old mice (18-21 mo) infected with M. avium had attenuated HO-1 response with diffuse inflammation, high burden of mycobacteria, poor granuloma formation, and decreased survival (45%), while young mice (4-6 mo) showed tight, well-defined granuloma, increased HO-1 expression, and increased survival (95%). | 27694475 |
| Inflammation, myocardial injury | Altered Intercellular Communication | Neither additional laboratory parameters for inflammation and myocardial injury nor lung functional measurements differed significantly between the groups. | 27695304 |
| Tumor necrosis, Inflammation | Altered Intercellular Communication | Tumor necrosis factor-a-induced protein 8-like 2 (TIPE2), a new negative regulator of immunity, plays significant roles in modulating inflammation and tumorigenesis. | 27696294 |
| Inflammation, Secondary malignant neoplasm of liver | Altered Intercellular Communication | The prognostic role of systemic inflammation in patients undergoing resection of colorectal liver metastases: C-reactive protein (CRP) is a strong negative prognostic biomarker. | 27696432 |
| Inflammation, Neoplasms | Altered Intercellular Communication | Systemic inflammation has been associated with poor survival in several tumor types, but has been less extensively studied in resectable metastatic disease. | 27696432 |
| Inflammation, IL13 gene | Altered Intercellular Communication | Effects of leukotriene D4 and histamine nasal challenge on airway responsiveness and inflammation in persistent allergic rhinitis patients. | 27696764 |
| Renal Insufficiency, Inflammation | Altered Intercellular Communication | TLT size was associated with impaired renal function and increased expression of proinflammatory cytokines and homeostatic chemokines, indicating a possible contribution of TLTs to sustained inflammation after injury. | 27699223 |
| Inflammation, Cytopenia | Altered Intercellular Communication | Shortly after engraftment with UCB, these mice develop a severe, fatal macrophage activation syndrome (MAS) characterized by a progressive drop in rbc numbers, increased reticulocyte counts, decreased rbc half-life, progressive cytopenias, and evidence of chronic inflammation, including elevated human IL-6. | 27699249 |
| Inflammation, Fibrosis Assessment, Muscular Atrophy | Altered Intercellular Communication | Hematoxylin Eosin and Azan-Mallory staining were used to detect muscle atrophy, inflammation, and fibrosis, respectively. | 27699951 |
| Eosinophilic infiltration of the esophagus, Inflammation, Jersey Island | Altered Intercellular Communication | Four of five patients with JE and NE had severe inflammation with eosinophilic infiltration of the esophageal muscle layer (73.8+-50.3 eosinophils/HPF) with no epithelial eosinophils. | 27699951 |
| Heart Diseases, Inflammation, Rheumatoid Arthritis, Degenerative polyarthritis | Altered Intercellular Communication | The administration of krill oil is reported to mitigate inflammation in patients with cardiac disease, rheumatoid arthritis, or osteoarthritis. | 27701428 |
| Inflammation, Chronic Kidney Diseases | Altered Intercellular Communication | Plasma pentosidine is markedly elevated in CKD and associates with low GFR, oxidative stress and inflammation, and is an independent predictor of mortality in CKD patients. | 27701453 |
| Communicable Diseases, Lower gastrointestinal hemorrhage, Inflammation | Altered Intercellular Communication | The aim of this study was to examine whether low-grade inflammation (LGI) is associated with a subsequently increased risk of infection. | 27701463 |
| Cholecystitis, Diverticulitis | Altered Intercellular Communication | We report the case of a patient with evidence of duodenal diverticulitis in association with gallbladder inflammation by contiguity, as well as his diagnosis and management. | 27701888 |
| Inflammation, TRPV6 gene | Altered Intercellular Communication | Our data demonstrate that propolis pretreatment shows immunomodulatory effects on both healthy donors and ATL patients adherent cells, increasing IL-4 and IL-17 and decreasing IL-10, in either the presence or absence of the L. braziliensis infection, demonstrating that propolis contributes with the decrease of the inflammation and could also contribute with parasite control. | 27702443 |
| Pain Distress Question, Photophobia, Inflammation, Epithelial | Altered Intercellular Communication | Patients with limbal stem cell deficiency (LSCD) often experience pain and photophobia due to recurrent epithelial defects and chronic inflammation of the cornea. | 27702552 |
| Inflammation, Data types - Address | Altered Intercellular Communication | Similar to human AD, robust TH1, TH2, and also TH17 activation are seen in IL-23-injected and NC/Nga mice, with similar but weaker inflammation in ovalbumin-challenged mice. | 27702671 |
| Inflammation, Psychiatry Specialty, Endothelial dysfunction | Altered Intercellular Communication | All patients underwent brain magnetic resonance imaging; had blood samples taken for markers of inflammation, endothelial dysfunction, cholesterol, and autoantibodies; and underwent cognitive and psychiatric testing. | 27703087 |
| Inflammation, Mycoses, Pneumonia | Altered Intercellular Communication | Invasive fungal infection was diagnosed in four patients, idiopathic acute fibrinous and organising pneumonia in three patients, and a granulomatous inflammation of undetermined origin in one patient. | 27704258 |
| Acute Lung Injury, Primary malignant neoplasm, Small cell carcinoma of lung | Altered Intercellular Communication | Prognostic Significance of Modified Advanced Lung Cancer Inflammation Index (ALI) in Patients with Small Cell Lung Cancer_ Comparison with Original ALI. | 27706243 |
| Acute Lung Injury, Pneumonitis, Small cell carcinoma of lung | Altered Intercellular Communication | Advanced lung cancer inflammation index (ALI, body mass index [BMI] x serum albumin/neutrophil-lymphocyte ratio [NLR]) has been shown to predict overall survival (OS) in small cell lung cancer (SCLC). | 27706243 |
| Inflammation, Dryness (characteristic), Autoimmune Disorder, CTCAE | Altered Intercellular Communication | Because TO is a disorder of autoimmune origin, we assumed that the association between TO and dry eye is related to inflammation. | 27706674 |
| Inflammation, Neoplasms | Altered Intercellular Communication | Strong evidence suggests that cancer-associated inflammation promotes tumor growth and progression, and interleukin-6 (IL6) is an important modulator of inflammation. | 27706719 |
| Hepatitis, Liver Cirrhosis | Altered Intercellular Communication | Macrophages play a key role in liver inflammation and are involved in the pathogenesis of cirrhosis and complications. | 27706896 |
| Airway structure, Rhinitis | Altered Intercellular Communication | The incompletely controlled group was older (P < .05), and had more airflow limitation, more airway inflammation, and more severe rhinitis symptoms (all P < .001). | 27707660 |
| Inflammation, Primary malignant neoplasm, Hepatitis B | Altered Intercellular Communication | Hepatitis B virus X induces inflammation and cancer in mice liver through dysregulation of cytoskeletal remodeling and lipid metabolism. | 27708241 |
| Inflammation, Endothelial dysfunction | Altered Intercellular Communication | A cross-sectional comparison of circulating resistin, sCD40L, as a marker of platelet-mediated inflammation, asymmetric dimethylarginine (ADMA), endothelial dysfunction marker, Dickkopf (DKK)-1, reflecting the inflammatory interaction between platelets and endothelial cells, and urinary 8-iso-PGF2a and 11-dehydro-TxB2, reflecting in vivo lipid peroxidation and platelet activation, respectively, was performed between 79 T2DM patients and 30 healthy subjects. | 27709225 |
| Diastolic dysfunction, ETV3 wt Allele | Altered Intercellular Communication | This suggests the important role of sex hormonal effects in the development of LV diastolic dysfunction in relation to MetS in this population. | 27710153 |
| Inflammation | Altered Intercellular Communication | Serum and AF LBP levels showed a positive correlation with surrogate markers of inflammation. | 27712029 |
| Inflammation, Obesity | Altered Intercellular Communication | The relationship between circulating visfatin/nicotinamide phosphoribosyltransferase, obesity, inflammation and lipids profile in elderly population, determined by structural equation modeling. | 27712122 |
| Inflammation | Altered Intercellular Communication | This indicates that circulating visfatin/NAMPT can be considered as a novel surrogate marker of systemic inflammation associated with fat depot, especially visceral, in the elderly population. | 27712122 |
| Inflammation, Atrial Fibrillation, Atrial Fibrillation by ECG Finding | Altered Intercellular Communication | The relation between inflammation and prothrombotic state in atrial fibrillation (AF) is well recognized. | 27712649 |
| Inflammation, Cerebrovascular accident | Altered Intercellular Communication | This suggests a potential role for high-sensitivity C-reactive protein (hs-CRP), a marker of systemic inflammation, in improving prediction of stroke in participants with AF. | 27712649 |
| Inflammation, Chronic Obstructive Airway Disease, Airway Obstruction | Altered Intercellular Communication | Elevated circulating PAI-1 levels are related to lung function decline, systemic inflammation, and small airway obstruction in chronic obstructive pulmonary disease. | 27713627 |
| ARCN1 gene, Inflammation, Chronic Obstructive Airway Disease | Altered Intercellular Communication | Plasminogen activator inhibitor-1 (PAI-1) and soluble urokinase-type plasminogen activator receptor (suPAR) participate in inflammation and tissue remolding in various diseases, but their roles in chronic obstructive pulmonary disease (COPD) are not yet clear. | 27713627 |
| ARCN1 gene, Inflammation, Airway Obstruction, Ovalocytosis, Malaysian-Melanesian-Filipino Type | Altered Intercellular Communication | This study aimed to investigate if PAI-1 and suPAR were involved in systemic inflammation and small airway obstruction (SAO) in COPD. | 27713627 |
| ARCN1 gene, Inflammation, Ovalocytosis, Malaysian-Melanesian-Filipino Type | Altered Intercellular Communication | Our findings first illustrate that elevated serum PAI-1 levels are related to the lung function decline, systemic inflammation, and SAO in COPD, suggesting that PAI-1 may play critical roles in the pathogenesis of COPD. | 27713627 |
| Airway structure | Altered Intercellular Communication | Fractional exhaled nitric oxide (FeNO) is an easy, sensitive, reproducible, and noninvasive marker of eosinophilic airway inflammation. | 27713629 |
| Celiac Disease, Inflammation | Altered Intercellular Communication | Celiac disease (CD) is an autoimmune condition, characterized by inflammation of the small intestine. | 27714440 |
| Hypogammaglobulinemia | Altered Intercellular Communication | Asthma and Hypogammaglobulinemia: an Asthma Phenotype with Low Type 2 Inflammation. | 27714565 |
| Inflammation | Altered Intercellular Communication | These patients have low type-2 inflammation markers. | 27714565 |
| Inflammation, Obesity | Altered Intercellular Communication | Correlation of TLR4 and KLF7 in Inflammation Induced by Obesity. | 27714571 |
| Inflammation, Obesity | Altered Intercellular Communication | Objective Recent studies have revealed a link between toll-like receptors (TLRs), Kruppel-like factors (KLFs), and the adipose tissue inflammation associated with obesity. | 27714571 |
| Inflammation, Obesity | Altered Intercellular Communication | TLR4 is associated with chronic inflammation in obesity. | 27714571 |
| Inflammation | Altered Intercellular Communication | KLF7 is known to play an important role in the differentiation of adipocytes, but its role in visceral adipose tissue inflammation has not yet been investigated. | 27714571 |
| Inflammation, Obesity | Altered Intercellular Communication | Thus, the objective of this study was to determine the correlation of TLR4 and KLF7 in inflammation induced by obesity. | 27714571 |
| Inflammation, Obesity | Altered Intercellular Communication | Conclusion Higher expression of TLR4 and KLF7 may play a vital role in the process of inflammation induced by obesity in visceral adipose tissue. | 27714571 |
| palladium, Inflammation, Congestive heart failure | Altered Intercellular Communication | The study hypothesis stated that elimination of chronic inflammation caused by PD has a significant impact on inflammation markers and, secondarily, also on the course and prognosis of CHF. | 27714722 |
| Inflammation, Overweight | Altered Intercellular Communication | Yeast b-Glucan Modulates Inflammation and Waist Circumference in Overweight and Obese Subjects. | 27715351 |
| Inflammation | Altered Intercellular Communication | Increased inflammation occurs with excessive adiposity and yeast b-glucan modulates immune responses. | 27715351 |
| Inflammatory abnormality of the eye, Ulcer | Altered Intercellular Communication | Clinically, the ulcers presented as non-infiltrated lesions with a modicum of other ocular inflammation. | 27715362 |
| Inflammation, Akkermansia | Altered Intercellular Communication | The link between Akkermansia, gut inflammation and C. difficile colonisation merits further investigations. | 27716140 |
| Inflammation, Liver carcinoma, FAM126A gene | Altered Intercellular Communication | It has been reported that higher levels of oxidative stress and inflammation play a key role in the progression of hepatocellular carcinoma (HCC) after surgery. | 27716246 |
| Inflammation, FAM126A gene | Altered Intercellular Communication | In conclusion, we demonstrated that a dose of 300 mg/d of coenzyme Q10 supplementation significantly increased the antioxidant capacity and reduced the oxidative stress and inflammation levels in HCC patients after surgery. | 27716246 |
| Destruction of tissue, Inflammation | Altered Intercellular Communication | In part A, sarilumab 150 and 200 mg every 2 weeks (q2w) significantly reduced biomarkers of tissue destruction, cartilage degradation, and synovial inflammation at both 2 and 12 weeks posttreatment (p < 0.05 vs placebo). | 27716324 |
| Knee Injuries, Inflammation, Fracture | Altered Intercellular Communication | Following knee injury, this activation is instant and associated with inflammation as well as with the presence of osteochondral fractures. | 27716448 |
| Inflammation, Observation Method - Coagulation, Ischemia | Altered Intercellular Communication | Classification according to their main function showed alterations related to coagulation, inflammation, oxidative stress, response to ischemia and lipid metabolism, defining 4 different molecular panels that characterize AS with high specificity and sensitivity. | 27716559 |
| Inflammatory abnormality of the eye, Uveitis | Altered Intercellular Communication | Pembrolizumab has been associated with rapid onset of ocular inflammation and uveitis. | 27716999 |
| Inflammation | Altered Intercellular Communication | Tuberculosis-diabetes co-morbidity (TB-DM) is characterized by increased inflammation with elevated circulating levels of inflammatory cytokines and other factors. | 27717783 |
| Inflammation | Altered Intercellular Communication | Our data demonstrate that TB-DM is associated with heightened levels of circulating angiogenic factors, possibly reflecting both dysregulated angiogenesis and exaggerated inflammation. | 27717783 |
| Inflammation | Altered Intercellular Communication | Inflammation can be acute or chronic based on clinical history, and it can be suppurative based on the presence of micro or macro abscess formation within the substance of the gland. | 27717819 |
| Fibrous histiocytoma of tendon sheath | Altered Intercellular Communication | Coexisting sarcoidal granulomatous inflammation and diffuse tenosynovial giant cell tumor of the knee after a total knee replacement: a case report. | 27717976 |
| Granulomatous inflammation, Fibrous histiocytoma of tendon sheath | Altered Intercellular Communication | Histologically, the mass from the posterior joint space showed characteristic features of diffuse tenosynovial giant cell tumor, while the synovium from the anterior compartment demonstrated sarcoidal granulomatous inflammation. | 27717976 |
| Abnormal renal function, Inflammation, Cardiovascular Diseases | Altered Intercellular Communication | Individuals with a combination of elevated cathepsin L and increased inflammation, kidney dysfunction, or prevalent cardiovascular disease had a markedly increased risk, while no increased risk was associated with elevated cathepsin L, in the absence of these disease states. | 27718373 |
| Asthma, allergic inflammation, Rhinitis, Allergy - Charge Type Reason | Altered Intercellular Communication | Five clusters (designated A through E) were distinguished by indicators of asthma and rhinitis severity, pulmonary physiology, allergy (sensitization and total serum IgE), and allergic inflammation. | 27720016 |
| Asthma, Rhinitis | Altered Intercellular Communication | In comparison to other clusters, cluster A was distinguished by lower allergy/inflammation, minimally symptomatic asthma and rhinitis, and normal pulmonary physiology. | 27720016 |
| Cluster, Asthma, Inflammation, Allergy - Charge Type Reason | Altered Intercellular Communication | Cluster B had highly symptomatic asthma despite high step-level treatment, lower allergy and inflammation, and mildly altered pulmonary physiology. | 27720016 |
| Inflammation, Asthma, Rhinitis, Allergy - Charge Type Reason | Altered Intercellular Communication | Cluster C had minimally symptomatic asthma and rhinitis, intermediate allergy and inflammation, and mildly impaired pulmonary physiology. | 27720016 |
| Asthma, Rhinitis | Altered Intercellular Communication | Clusters D and E exhibited progressively higher asthma and rhinitis symptoms and allergy/inflammation. | 27720016 |
| allergic inflammation, Allergy - Charge Type Reason | Altered Intercellular Communication | However, a symptomatic phenotype with little allergy or allergic inflammation was identified. | 27720016 |
| Obesity, Allergic sensitization, Asthma, allergic inflammation, Rhinitis | Altered Intercellular Communication | On the basis of medical evidence in the published literature, we developed a conceptual model to describe how 8 risk-factor domains (allergen sensitization, allergic inflammation, pulmonary physiology, stress, obesity, vitamin D, environmental tobacco smoke [ETS] exposure, and rhinitis severity) are linked to asthma severity. | 27720018 |
| Allergy - Charge Type Reason, Allergic sensitization, Asthma, allergic inflammation, Rhinitis | Altered Intercellular Communication | An allergy pathway (linking allergen sensitization, allergic inflammation, pulmonary physiology, and rhinitis severity domains to asthma severity) and the ETS exposure pathway (linking ETS exposure and pulmonary physiology domains to asthma severity) exerted significant effects on asthma severity. | 27720018 |
| Burn Specimen Source Codes, Gastrointestinal inflammation | Altered Intercellular Communication | While the most obvious impact of burn is on the skin, systemic responses also occur after burn, including intestinal inflammation. | 27720266 |
| Inflammation, Dental Plaque | Altered Intercellular Communication | Inflammation and angiogenesis play major roles in carotid plaque vulnerability. | 27720278 |
| Inflammation, Dental Plaque | Altered Intercellular Communication | Presence of an ultrasound DWA was associated with more plaque hemosiderin (p = 0.0005) and inflammation (p = 0.019) on histopathology examination. | 27720278 |
| Uremia, Inflammation, Chronic Kidney Diseases | Altered Intercellular Communication | Cardiac changes observed in chronic kidney disease patients are of multifactorial origin including chronic uremia, hemodynamics or inflammation. | 27721315 |
| Inflammation, Dysbiosis | Altered Intercellular Communication | CONCLUSIONS Results suggest dysfunctional immune activation in ILL following exercise and that prokaryotic viruses may contribute to mucosal inflammation and bacterial dysbiosis. | 27721367 |
| Refractory anemias, Inflammation, Proteus mirabilis | Altered Intercellular Communication | These results indicate that P. mirabilis through the molecular mimicry mechanism leads to inflammation and damage of the joints in RA. | 27722971 |
| Inflammation, Fever, CTCAE | Altered Intercellular Communication | Periodic fever syndrome (PFS) conditions are characterized by recurrent attacks of fever and localized inflammation. | 27723279 |
| Airway structure, Asthma | Altered Intercellular Communication | We sought to compare airway inflammation and its relationship to asthma control in aged versus younger patients and determine whether differences are asthma specific or caused by "inflamm-aging." | 27725186 |
| Airway structure, Asthma | Altered Intercellular Communication | Knowledge of the aging effect on airway inflammation and asthma control is limited. | 27725186 |
| Airway structure, Asthma | Altered Intercellular Communication | We sought to compare airway inflammation and its relationship to asthma control in aged versus younger patients and determine whether differences are asthma specific or caused by "inflamm-aging." | 27725186 |
| Airway structure, Asthma | Altered Intercellular Communication | Differences in airway inflammation can contribute to diminished asthma control in the aged. | 27725186 |
| Inflammation | Altered Intercellular Communication | The condition is characterized by epithelial proliferation, fibrovascular growth, chronic inflammation, and prominent extracellular matrix remodeling. | 27725197 |
| Endophthalmitis, CTCAE, Hypopyon | Altered Intercellular Communication | All presented with aggressive inflammation (hypopyon in two cases) and two were treated for suspected endophthalmitis. | 27726461 |
| Keratitis, Episcleritis, Orbital Pseudotumor, Traumatic iritis, Endophthalmitis, CTCAE | Altered Intercellular Communication | Patients with keratitis, episcleritis, orbital inflammation, post-surgical endophthalmitis, traumatic iritis, and corneal graft rejection were excluded. | 27726522 |
| Inflammation, Epithelial ovarian cancer | Altered Intercellular Communication | Chronic inflammation has been implicated in the development of epithelial ovarian cancer (EOC); yet the contribution of inflammatory foods and nutrients to EOC risk has been understudied. | 27727481 |
| Inflammation, Acute pulmonary embolism, APEX1 protein, human | Altered Intercellular Communication | The relationship between inflammation and mortality after acute pulmonary embolism (APE) has previously been investigated with different variables (platelet/lymphocyte ratio, etc). | 27727508 |
| Inflammation | Altered Intercellular Communication | LMR as a novel marker of inflammation seemed to be an independent predictor of short-term mortality in patients with APE. | 27727508 |
| Inflammation, Treatment/Psychosocial Effects | Altered Intercellular Communication | Psychosocial distress and inflammation: Which way does causality flow? | 27728857 |
| Inflammation, Treatment/Psychosocial Effects | Altered Intercellular Communication | This study queried causal direction in linkages of inflammation with psychosocial distress. | 27728857 |
| Inflammation, Anxiety, CTCAE 3.0, Depression, CTCAE | Altered Intercellular Communication | Inflammation was indicated by C-reactive protein, and distress by depression, anxiety, as well as stress. | 27728857 |
| Inflammation, Treatment/Psychosocial Effects | Altered Intercellular Communication | Rather than being an outcome of psychosocial distress, inflammation was a predictor of it. | 27728857 |
| Inflammation, Depression, CTCAE | Altered Intercellular Communication | Linkages were gender differentiated, with inflammation seeming to induce depression among men but stress among women. | 27728857 |
| Inflammation | Altered Intercellular Communication | Contrary to previous literature, inflammation may not be a mechanism through which psychosocial distress gets "under the skin" to cause cardiovascular and metabolic issues. | 27728857 |
| Inflammation, Interferon-Related DNA Damage Resistance Gene Signature, Coronary Artery Disease, Vasculitis of large artery | Altered Intercellular Communication | As inflammation may play a role, we wanted to compare the occurrence and extent of inflammatory cell infiltrates (ICIs), small vessel vasculitis, and the amount of adipose tissue and collagen in cardiac biopsies taken from patients with coronary artery disease with and without IRDs. | 27729056 |
| Inflammation | Altered Intercellular Communication | Our results do not support the notion that inflammation in cardiac peri-, epi-, and myocardium plays a more important role in CVD of patients with IRD than non-IRD patients. | 27729056 |
| Idiopathic Inflammatory Myopathies, IgG4-Related Sclerosing Disease, Pseudotumor | Altered Intercellular Communication | IgG4-related disease (IgG4-RD) is an idiopathic inflammatory condition that causes pseudotumor formation in single or multiple organs, including those of the head and neck. | 27729479 |
| Intraocular inflammation | Altered Intercellular Communication | The included cases were all non-HIV-infected patients presenting with intraocular inflammation from 2002 to 2014 at Kyung Hee University Hospital. | 27729756 |
| Inflammation, Heart failure | Altered Intercellular Communication | A score composed by these factors (denominated HIS [Heart Failure, Inflammation, and female Sex]) showed a sensitivity of 79% and a specificity of 60% (area under receiver operating characteristic curve 0.695, P = 0.002) in identifying patients with a positive transesophageal echo; traditional risk scores did not perform as well. | 27730663 |
| Inflammation, Pathology | Altered Intercellular Communication | Our results suggest that aneuploid cells that accumulate during aging in some mammalian tissues potentially contribute to age-related pathologies and inflammation through SASP secretion. | 27731420 |
| Shock, Inflammation, Organ Dysfunction Scores | Altered Intercellular Communication | However, animal studies demonstrate that calcium administration during critical illness heightens inflammation and leads to shock, organ dysfunction, and mortality. | 27732742 |
| Diarrhea, Inflammation, Dermatitis acneiform, Fatigue | Altered Intercellular Communication | The most common treatment-related adverse events in the 71 patients who received treatment across five dose levels were diarrhea (59.2%), mucosal inflammation (47.9%), and fatigue and acneiform dermatitis (45.1% each). | 27733479 |
| Toxic effect, Inflammatory disease of mucous membrane | Altered Intercellular Communication | The most common dose-limiting toxicity was mucosal inflammation. | 27733479 |
| Communicable Diseases, Inflammation, Deglutition Disorders | Altered Intercellular Communication | We aimed to confirm that stroke-induced immunodepression syndrome is associated with stroke-associated pneumonia independently from dysphagia by investigating the predictive properties of monocytic HLA-DR expression as a marker of immunodepression as well as biomarkers for inflammation (interleukin-6) and infection (lipopolysaccharide-binding protein). | 27733675 |
| Inflammation, Pancreatitis | Altered Intercellular Communication | The disease course of acute pancreatitis (AP) ranges from mild and self-limiting to severe inflammation, associated with significant morbidity and mortality. | 27734249 |
| Single organ dysfunction, Inflammation | Altered Intercellular Communication | The a1-microglobulin/creatinine ratio upon presentation with AP is related to inflammation and predicts development of organ failure. | 27734249 |
| Inflammation | Altered Intercellular Communication | Abdominal fat has been recognized as the most hormonally active tissue secreting a variety of adipocytokines and, therefore, potentially contributing to inflammation. | 27734324 |
| Inflammation, Fibrosis Assessment | Altered Intercellular Communication | Inflammation, regeneration and fibrosis are observed at the whole organ level, both in dystrophin-negative and dystrophin-positive portions of the chimeric tissues. | 27734557 |
| Inflammation, Crohn Disease | Altered Intercellular Communication | Monitoring mucosal inflammation is crucial to prevent complications and disease progression in Crohn's disease (CD). | 27734914 |
| Inflammatory disease of mucous membrane | Altered Intercellular Communication | Clinical activity scores and non-invasive biochemical markers do not correlate well with mucosal inflammation. | 27734914 |
| Inflammation, Noncommunicable Diseases | Altered Intercellular Communication | n-3-polyunsaturated fatty acids and polyphenols are potential key factors for the treatment and prevention of chronic inflammation associated to ageing and non-communicable diseases. | 27735833 |
| Inflammation, Pain Distress Question | Altered Intercellular Communication | Consecutive nonsteroidal anti-inflammatory-drugs (NSAIDs) poor responders with chronic inflammation and pain due to knee arthrosis were assessed (15 subjects, age: 67.2 +- 7.9, body mass index: 30.6 +- 7.1, men/women:2/13). | 27737573 |
| Inflammation, Synovitis | Altered Intercellular Communication | Only the DCE-MRI variable MExNvoxel (surrogate of the volume and degree of synovitis) and the macroscopic score showed correlations above the pre-specified threshold for acceptance with histological inflammation. | 27737813 |
| NCI CTEP SDC Myelodysplastic Syndrome Sub-Category Terminology | Altered Intercellular Communication | She had no identifiable inflammatory condition and did not meet the criteria for myelodysplastic syndrome. | 27737867 |
| Inflammation, FAM126A gene | Altered Intercellular Communication | Inflammation is closely related to the initiation and development of HCC. | 27739418 |
| Inflammation, Liver carcinoma, Liver Cirrhosis, FAM126A gene | Altered Intercellular Communication | However, a long period of elevated systemic venous pressure and low cardiac output after the procedure result in chronic inflammation and liver cirrhosis, which may eventually lead to the occurrence of hepatocellular carcinoma (HCC). | 27741102 |
| Inflammation, Sleep Apnea, Obstructive, Impaired cognition, Osage language | Altered Intercellular Communication | Pediatric obstructive sleep apnea (OSA) is associated with chronic systemic inflammation and with cognitive impairments. | 27741107 |
| Airway structure | Altered Intercellular Communication | Genetic susceptibility for air pollution-induced airway inflammation in the SALIA study. | 27741447 |
| Inflammation | Altered Intercellular Communication | Long-term air pollution exposure has been associated with chronic inflammation providing a link to the development of chronic health effects. | 27741447 |
| Airway structure, Inflammatory disorder | Altered Intercellular Communication | Furthermore, there is evidence that pathways activated by endoplasmatic reticulum (ER) stress induce airway inflammation and thereby play an important role in the pathogenesis of inflammatory diseases. | 27741447 |
| Inflammation | Altered Intercellular Communication | These results indicate that genetic variation in the ER stress pathway might play a role in air pollution induced inflammation in the lung. | 27741447 |
| Inflammation, Pyoderma Gangrenosum | Altered Intercellular Communication | Speed of healing, IGA, and resolution of inflammation were all shown to be good predictors of eventual healing of pyoderma gangrenosum. | 27742168 |
| Cell Death, Inflammation | Altered Intercellular Communication | Notably, there is no altered expression in proteins associated with cell death, ubiquitin or inflammation. | 27742266 |
| Communicable Diseases, Inflammation | Altered Intercellular Communication | The bronchoalveolar lavage showed marked signs of acute inflammation without recovering any infectious agent. | 27742338 |
| Inflammation | Altered Intercellular Communication | Immune aging manifests with a combination of failing adaptive immunity and insufficiently restrained inflammation. | 27742546 |
| Refractory anemias, Rheumatoid Arthritis, Inflammation | Altered Intercellular Communication | In patients with rheumatoid arthritis (RA), T cell aging occurs prematurely, but the mechanisms involved and their contribution to tissue-destructive inflammation remain unclear. | 27742546 |
| Inflammation, Degenerative disorder | Altered Intercellular Communication | Low-grade inflammation is associated with an increased risk of chronic degenerative disease, but its relationship with mortality is less well explored. | 27742767 |
| Inflammation, Health-Related Behavior, Chronic disease | Altered Intercellular Communication | As compared to subjects in the lowest quartile of the low-grade inflammation score, those in the highest category had a significantly increased risk in overall mortality (HR=1.44; 1.17-1.77), independently of possible confounders, including the presence of chronic diseases and a number of health-related behaviors. | 27742767 |
| Inflammation, diabetic, Cardiovascular Diseases | Altered Intercellular Communication | The magnitude of the association of low-grade inflammation with mortality was relatively higher in type 2 diabetic patients (HR=2.90; 1.74-4.84) and in individuals with a history of cardiovascular disease (HR=2.48; 1.50-4.11) as compared to their counterparts who were free from the disease. | 27742767 |
| Inflammation, Organ Dysfunction Scores | Altered Intercellular Communication | The neutrophil-to-lymphocyte ratio (NLR) is a marker that reflects systemic inflammation and organ dysfunction. | 27743125 |
| Inflammation, Cardiovascular Diseases | Altered Intercellular Communication | Observational associations between inflammation and cardiovascular disease are interesting, but randomised experimental data are lacking. | 27744141 |
| Inflammation, Primary malignant neoplasm | Altered Intercellular Communication | The effect inflammation has on cancer prognosis is marked by the presence of cytokines and chemokines. | 27744625 |
| Primary malignant neoplasm, Acute inflammation, Cardiovascular Diseases | Altered Intercellular Communication | A total of 23 233 middle-aged participants (8862 men and 14 371 women) who were free from cardiovascular disease, cancer, and acute inflammation (defined by a CRP level >=10 mg/L) were drawn from 11 rural communities in Korea between 2005 and 2011. | 27744669 |
| FTO protein, human, Inflammation | Altered Intercellular Communication | Relationships between the intestinal microbiota, intestinal permeability and inflammation in the context of risk for obesity-associated disease continue to be of interest. | 27745826 |
| Chronic inflammation | Altered Intercellular Communication | Defective Signaling in the JAK-STAT Pathway Tracks with Chronic Inflammation and Cardiovascular Risk in Aging Humans. | 27746093 |
| Inflammation | Altered Intercellular Communication | Chronic inflammation, a decline in immune responsiveness, and reduced cardiovascular function are all associated with aging, but the relationships among these phenomena remain unclear. | 27746093 |
| Inflammation | Altered Intercellular Communication | Targeting chronic inflammation may ameliorate this deficiency in cellular responsiveness and improve cardiovascular function. | 27746093 |
| nervous system disorder, Communicable Diseases, Inflammation, Systemic disease | Altered Intercellular Communication | The reference standard was the diagnosis classified into five categories: 1) CNS infection; 2) CNS inflammation without infection; 3) other neurological disorder; 4) non-neurological infection; and 5) other systemic disorder. | 27746160 |
| ARCN1 gene, Inflammation | Altered Intercellular Communication | A subset of patients with COPD demonstrates eosinophilic inflammation either in their sputum or blood. | 27746201 |
| Inflammation, Bacterial Infections | Altered Intercellular Communication | Dusquetide, a novel Innate Defense Regulator, modulates the innate immune system at a key convergence point in intracellular signaling pathways and has demonstrated activity in both reducing inflammation and increasing clearance of bacterial infection. | 27746305 |
| Inflammation | Altered Intercellular Communication | However, KCOTs with intense inflammation showed higher Ki-67 expression (p < 0.001). | 27747382 |
| Granulomatous inflammation, Sarcoidosis, Granulomatous disorder | Altered Intercellular Communication | Given the multisystem involvement with significant chest findings, tissue findings of granulomatous disease, and negative workup for other causes of granulomatous inflammation, both cases were diagnosed with active disseminated sarcoidosis, and treated with corticosteroids. | 27748327 |
| Gastrointestinal inflammation | Altered Intercellular Communication | The role of IL-33 in intestinal inflammation is incompletely understood, with both pro-inflammatory and regulatory properties described. | 27748438 |
| Inflammatory Bowel Diseases, Tumor necrosis, Rheumatoid Arthritis | Altered Intercellular Communication | Tumor necrosis factor alpha (TNF alpha) antagonists are biologic agents used in the management of inflammatory conditions such as rheumatoid arthritis, seronegative spondyloarthropathies and inflammatory bowel disease. | 27748629 |
| Refractory anemias, Inflammation, PROS1 gene, Synovitis | Altered Intercellular Communication | Polyarticular PsA patients in remission had lower levels of local (US synovitis) and systemic inflammation than RA patients in remission, even though a significantly higher percentage of PsA patients were on tapered doses of anti-TNF, mainly in monotherapy. | 27749227 |
| Musculoskeletal, Inflammation, Psoriasis | Altered Intercellular Communication | Part of the psoriasis patients with musculoskeletal complaints will have inflammation of the entheses. | 27749228 |
| Inflammation | Altered Intercellular Communication | Active ultrasound inflammation contained positive power Doppler signal or in case of the plantar aponeurosis increased thickness. | 27749228 |
| Inflammation, Sore to touch, Pain Distress Question | Altered Intercellular Communication | Active ultrasound inflammation accompanied with pain or tenderness at the enthesis was found in 36% of the patients (n=40). | 27749228 |
| Inflammation, Synovitis | Altered Intercellular Communication | MRI synovitis was not correlated with radiological scores, clinical or biologic markers of inflammation. | 27749237 |
| Ischemia, Inflammation, Ulcer | Altered Intercellular Communication | Ischaemia was defined as lower blood flow or skin temperature (and inflammation as higher) within the ulcer, compared to a non-affected site. | 27749241 |
| Inflammation, Ulcer | Altered Intercellular Communication | Inflammation in the surrounding area was identified for all ulcers by LDI but not thermography. | 27749241 |
| Inflammation, Acute Coronary Syndrome, GDC AJCC Clinical Stage Terminology | Altered Intercellular Communication | We examined relationships between psychological constructs and markers of inflammation, endothelial function, and myocardial strain in a cohort of post-acute coronary syndrome (ACS) patients. | 27749683 |
| Inflammation, Anxiety, CTCAE 3.0, Amino-terminal pro-brain natriuretic peptide, Endothelial dysfunction, Bipolar Disorder | Altered Intercellular Communication | In concurrent analyses, depressive symptoms were associated with elevated markers of inflammation (interleukin-17: b = .047; 95% confidence interval [CI] = .010-.083]), endothelial dysfunction (endothelin-1: b = .020; 95% [CI] = .004-.037]), and myocardial strain (N-terminal pro-B-type natriuretic peptide: b = .045; 95% [CI] = .008-.083]), independent of age, sex, medical variables, and anxiety, whereas anxiety was not associated with these markers in multivariable adjusted models. | 27749683 |
| Inflammation, Bipolar Disorder, Myocardial, Endothelial dysfunction, GDC AJCC Clinical Stage Terminology | Altered Intercellular Communication | Depressive symptoms were associated with more inflammation, myocardial strain, and endothelial dysfunction in the 6 months after ACS, whereas positive psychological constructs were linked to better endothelial function. | 27749683 |
| Inflammation, Fibrosis Assessment | Altered Intercellular Communication | Histologic fibrosis was staged and inflammation activity was graded based on the METAVIR scoring system on liver biopsy specimens. | 27750231 |
| Inflammation, Fibrosis Assessment, Liver Stiffness | Altered Intercellular Communication | The liver stiffness values by using 2D SWE and RTE both increased in parallel with the degree of liver fibrosis and the grade of inflammation. | 27750231 |
| Inflammation, Cyclophosphamide/Vincristine/Dacarbazine Regimen, Cardiovascular Diseases | Altered Intercellular Communication | These toxins induce inflammation and are associated with cardiovascular disease (CVD). | 27751361 |
| Inflammation, Dental Plaque, Atherosclerosis | Altered Intercellular Communication | Monocytes are known to play a key role in the initiation and progression of atherosclerosis and contribute to plaque destabilization through the generation of signals that promote inflammation and neoangiogenesis. | 27751505 |
| Inflammation, Thrombophilia | Altered Intercellular Communication | The coincidence of hyper-coagulation, cell senescence, and inflammation suggests the existence of a common underlying mechanism. | 27752126 |
| Inflammation, Sore to touch | Altered Intercellular Communication | He presented with normal vital signs, tenderness in upper abdominal quadrants, elevated lipase (909 units/L), lactate dehydrogenase (193 units/L), and an enlarged pancreas with surrounding inflammation on computed tomography. | 27753588 |
| Inflammation | Altered Intercellular Communication | Activated monocytes induce almost all tissue factor (TF) expression contributing to inflammation and coagulation. | 27753793 |
| Acute inflammation | Altered Intercellular Communication | In MH and ERM, topical diclofenac and betamethasone equally suppressed postoperative inflammation after the combined surgery, although diclofenac better controlled postoperative IOP. | 27754737 |
| Inflammation | Altered Intercellular Communication | In DME and RRD, both drugs were equally effective in suppressing inflammation and controlling IOP, but diclofenac showed weaker suppression following longer operation. | 27754737 |
| Inflammatory Bowel Diseases | Altered Intercellular Communication | Fecal HMGB1 Reveals Microscopic Inflammation in Adult and Pediatric Patients with Inflammatory Bowel Disease in Clinical and Endoscopic Remission. | 27755215 |
| Inflammation | Altered Intercellular Communication | Fecal high mobility group box 1 (HMGB1) has been suggested to be a novel noninvasive biomarker of gut inflammation. | 27755215 |
| Inflammatory Bowel Diseases, Inflammation, Gastrointestinal inflammation | Altered Intercellular Communication | We aimed to assess the reliability of fecal HMGB1, compared with fecal calprotectin (FC), in detecting intestinal inflammation in pediatric and adult patients with inflammatory bowel disease (IBD) and to evaluate the accuracy of HMGB1 in identifying patients with IBD in clinical and endoscopic remission who still have histologic features of inflammation. | 27755215 |
| Inflammation, Ulcerative Colitis, Crohn Disease | Altered Intercellular Communication | Moreover, in patients with clinical and endoscopic remission only fecal HMGB1 showed a strong match with the degree of histological scores of inflammation (CGHAS/IGHAS for Crohn's disease and Geboes Score for ulcerative colitis). | 27755215 |
| Inflammatory Bowel Diseases, Gastrointestinal inflammation | Altered Intercellular Communication | Fecal HMGB1 is confirmed to be a reliable biomarker of intestinal inflammation; indeed, it significantly correlates with fecal calprotectin in pediatric and adult IBD patients. | 27755215 |
| Inflammatory Bowel Diseases, Inflammation | Altered Intercellular Communication | Moreover, only fecal HMGB1 identifies histologic inflammation in subjects with IBD in clinical and endoscopic remission. | 27755215 |
| malignant disease, Inflammation, Traumatic injury, Communicable Diseases | Altered Intercellular Communication | Six older than 60 years old volunteers in both genders, 40 young female volunteers (no contraceptive drug, n = 18, contraceptive drug, n = 9, lactation, n = 9, pregnant, n = 4) were collected with following exclusion criteria, malignant disease, inflammation, infection, trauma and taking non-steroid anti-inflammatory drugs and antibiotics. | 27755396 |
| Symphysis Pubis Dysfunction | Altered Intercellular Communication | Decreases in PTH level can result from medical intervention (MPD) and surgical parathyroidectomy (PTX), or may occur spontaneously, usually associated with an underlying malnutrition-inflammation syndrome (SPD). | 27756251 |
| Inflammation, Stomach Neoplasms, Infection caused by Helicobacter pylori, Gastritis, Atrophic | Altered Intercellular Communication | Assessment of 18F-FDG uptake in the stomach reflecting active inflammation is useful in predicting patients with H. pylori infection and subsequent chronic atrophic gastritis which is closely associated with the risk of gastric neoplasms. | 27756255 |
| Papilledema, Vitreous inflammatory cells, Retinal Vasculitis, Retinal Hemorrhage, Unspecified visual loss, Infiltration | Altered Intercellular Communication | Acute Multifocal Hemorrhagic Retinal Vasculitis (AMHRV) is a rare disease with unknown incidence that presents with abrupt onset of visual loss associated with retinal vasculitis, retinal hemorrhage, non-confluent posterior retinal infiltrates, vitreous cellular inflammation and papillitis in, otherwise, healthy adult individuals. | 27756269 |
| Osteolysis | Altered Intercellular Communication | Lentivirus-mediated short hairpin RNA interference targeting TNF-alpha in macrophages inhibits particle-induced inflammation and osteolysis in vitro and in vivo. | 27756280 |
| Inflammation, PPP3CB wt Allele | Altered Intercellular Communication | Although it is known that immune reaction of LNB patients is dominated by Th1 and Th2 responses and patients have elevated numbers of B cells in their cerebrospinal fluid (CSF), not all the cells involved in inflammation and cytokine secretion have been characterized. | 27756335 |
| Airway structure, ARCN1 gene, Asthma | Altered Intercellular Communication | In conclusion, sputum biomarkers reflecting both airway inflammation and remodeling of the tissue show potential in differentiation between asthma, COPD, and ACOS. | 27757028 |
| Inflammation, hepcidin, Metabolic Syndrome X | Altered Intercellular Communication | This association persisted within strata defined by markers of the metabolic syndrome, markers of inflammation, or other markers of iron homeostasis, including hepcidin. | 27758018 |
| Autoimmune Diseases, Fibrosis Assessment, Lupus Erythematosus | Altered Intercellular Communication | Pristane-Accelerated Autoimmune Disease in (SWR X NZB) F1 Mice Leads to Prominent Tubulointerstitial Inflammation and Human Lupus Nephritis-Like Fibrosis. | 27760209 |
| Fibrosis Assessment, Interstitial inflammation, Disease | Altered Intercellular Communication | These include i) a stronger upregulation of the cytosolic nucleic acid sensing pathway, which is thought to be key component of the pathogenesis of the human disease, and ii) more prominent kidney interstitial inflammation and fibrosis, which have been both associated with poor prognosis in human LN. | 27760209 |
| Fibrosis Assessment, Conjunctivitis | Altered Intercellular Communication | Fifty-seven patients with OcMMP underwent detailed examination of conjunctival inflammation and fibrosis using fornix depth measurement. | 27760272 |
| Conjunctival shrinkage, Inflammation | Altered Intercellular Communication | Notably, eyes with no visible inflammation and raised conjunctival neutrophils were more likely to progress and have a greater degree of conjunctival shrinkage compared to those without raised neutrophils. | 27760272 |
| Inflammation, Malignant Neoplasms | Altered Intercellular Communication | FDG and F-2-fluorodeoxysorbitol (F-FDS) PET were performed to differentiate malignancy from inflammation. | 27764039 |
| Inflammation, Injury of liver | Altered Intercellular Communication | Hyperfibrinolysis may occur due to systemic inflammation or hepatic injury that occurs during liver resection. | 27765582 |
| Inflammation, Disease | Altered Intercellular Communication | Such an epigenetic signature may increase risk for diseases exacerbated by inflammation, and may contribute to health disparity. | 27765646 |
| Post-Traumatic Stress Disorder, Inflammation | Altered Intercellular Communication | Current posttraumatic stress disorder and exaggerated threat sensitivity associated with elevated inflammation in the Mind Your Heart Study. | 27765647 |
| Post-Traumatic Stress Disorder, Inflammation, Psychiatric | Altered Intercellular Communication | Elevated inflammation has been repeatedly observed in posttraumatic stress disorder (PTSD), and it may drive the development of both psychiatric symptoms and physical comorbidities. | 27765647 |
| Post-Traumatic Stress Disorder, Inflammation | Altered Intercellular Communication | However, it is not clear if elevated inflammation is a feature of both remitted and current PTSD, and little is known about relationships between specific clusters of PTSD symptoms and inflammation. | 27765647 |
| Inflammation | Altered Intercellular Communication | Exaggerated threat sensitivity, as indexed by threat reactivity and avoidance of perceived threats, may be particularly closely associated with inflammation. | 27765647 |
| Post-Traumatic Stress Disorder, Inflammation | Altered Intercellular Communication | Our data indicate that elevated inflammation may be a feature of current, but not remitted, PTSD. | 27765647 |
| Post-Traumatic Stress Disorder, Inflammation | Altered Intercellular Communication | Within patients with PTSD, higher threat reactivity was also associated with elevated inflammation. | 27765647 |
| Post-Traumatic Stress Disorder, Inflammation | Altered Intercellular Communication | A better understanding of the relationship between threat sensitivity and inflammation may inform interventions for patients with PTSD. | 27765647 |
| Inflammation, Diabetes Mellitus, Non-Insulin-Dependent | Altered Intercellular Communication | Isocaloric Diets High in Animal or Plant Protein Reduce Liver Fat and Inflammation in Individuals With Type 2 Diabetes. | 27765690 |
| Inflammation, Obesity | Altered Intercellular Communication | Ceramides are molecular lipids implicated in apoptosis, inflammation, obesity, and insulin resistance. | 27765765 |
| Inflammation, Anemia, Liver Dysfunction | Altered Intercellular Communication | They were characterized by anemia (low hemoglobin and hematocrit levels), inflammation (high leukocyte count, neutrophil count, C-reactive protein level, and body temperature), and hepatic and renal dysfunction (high aspartate aminotransferase, alanine aminotransferase and blood urea nitrogen levels). | 27766023 |
| Inflammation | Altered Intercellular Communication | Structural brain changes and all-cause mortality in the elderly population-the mediating role of inflammation. | 27766478 |
| Inflammation | Altered Intercellular Communication | While MRI brain changes have been related to mortality during ageing, the role of inflammation in this relationship remains poorly understood. | 27766478 |
| Inflammation, Atrophic | Altered Intercellular Communication | Our study supports a possible role for inflammation in the atrophy pathogenesis. | 27766478 |
| Necrotizing granulomatous inflammation | Altered Intercellular Communication | A combination of TB PCR, mycobacterial culture, and finding of necrotizing granulomatous inflammation provided the best diagnostic performance (sensitivity, specificity, positive predictive value, negative predictive value, and AUC of 75.0%, 100.0%, 100.0%, 95.6%, and 0.88, respectively). | 27766918 |
| Inflammation, Aortic Aneurysm, Atherosclerosis | Altered Intercellular Communication | Angiogenesis and inflammation are implicated in aortic aneurysm and atherosclerosis and regulated by angiopoietin-2 (Angpt2). | 27767064 |
| Inflammation, Aortic Aneurysm, Atherosclerosis | Altered Intercellular Communication | In conclusion, administration of rAngpt2 attenuated angiotensin II-induced aortic aneurysm and atherosclerosis in ApoE-/- mice associated with reduced aortic inflammation and angiogenesis. | 27767064 |
| Inflammation | Altered Intercellular Communication | The prognostic value of oxidative stress and inflammation in Chinese hemodialysis patients. | 27767372 |
| Inflammation | Altered Intercellular Communication | There is limited information about oxidative stress and inflammation on the mortality of Chinese hemodialysis (HD) patients. | 27767372 |
| Sepsis, Inflammation, Thrombosis | Altered Intercellular Communication | Soluble CD40 ligand (sCD40L) has been considered as a marker of thrombosis and inflammation in several diseases, including sepsis. | 27767979 |
| Inflammation, Septic Shock | Altered Intercellular Communication | Therefore, herein we evaluated association between sCD40L and markers of hemorheology and inflammation on context of septic shock. | 27767979 |
| Inflammation, Septic Shock | Altered Intercellular Communication | These results seem to highlight a possible association of sCD40L to endothelial function and inflammation in septic shock context. | 27767979 |
| Inflammation | Altered Intercellular Communication | FDG uptake in some of these lesions is suggestive of chronic inflammation. | 27768632 |
| Periorbital Infection, Orbital Pseudotumor | Altered Intercellular Communication | Transient episodes of orbital inflammation were noted after retrobulbar injections, but progression of orbital infection was halted and visual acuity restored with eventual hospital discharge. | 27768642 |
| Orbital Pseudotumor | Altered Intercellular Communication | However, physicians should be aware of the risk of transient orbital inflammation secondary to retrobulbar amphotericin B deoxycholate. | 27768642 |
| Inflammation, Neoplasms | Altered Intercellular Communication | In summary, loss of ASC driven tumor development is counterbalanced in the identical cell by the inhibition of pro-tumorigenic inflammation in the tumor cell itself. | 27768771 |
| ARCN1 gene, Inflammation | Altered Intercellular Communication | Combination prednisolone and low-dose cyclosporine A therapy inhibits these pro-inflammatory cells and may reduce systemic inflammation in COPD. | 27769261 |
| Inflammation, Malnutrition | Altered Intercellular Communication | The pathophysiology of individuals, considered to be malnourished in rich countries and in areas with endemic malnutrition, results predominantly from deficient nutrition combined with infection/inflammation. | 27769782 |
| Inflammation, Malnutrition | Altered Intercellular Communication | We therefore advise to consider the pathophysiology of malnourished individuals leading to inclusion of the following elements in the definition of malnutrition: a disordered nutritional state resulting from a combination of inflammation and a negative nutrient balance, leading to changes in body composition, function and outcome. | 27769782 |
| Inflammation, Cholangiocarcinoma, Tissue damage, Hepatobiliary Disorder, FBN2 wt Allele | Altered Intercellular Communication | The carcinogenic liver fluke Opisthorchis viverrini causes chronic inflammation in the bile duct and resulting in unremitting tissue damage that lead to hepatobiliary diseases, including cholangiocarcinoma (CCA). | 27769807 |
| atherosclerotic | Altered Intercellular Communication | Objectives Platelet-to-lymphocyte ratio is a novel biomarker, recently shown to be correlated with atherosclerotic inflammation. | 27770030 |
| Fracture | Altered Intercellular Communication | Inflammation surrounding such fractures may destroy tissue planes, making dissection more technically difficult. | 27770081 |
| Inflammation, Coronary Arteriosclerosis, Myocardium | Altered Intercellular Communication | PZ deficiency is found in AMI patients and could potentially reflect the myocardium injury, local coagulation activation and inflammation response during the acute phase of coronary atherosclerosis disease. | 27770663 |
| Inflammation, Blood Vessel | Altered Intercellular Communication | The main outcomes will be markers of lipid and DNA oxidation, inflammation, and vascular damage. | 27770787 |
| Inflammation, Rheumatoid Arthritis, Arthritis | Altered Intercellular Communication | Body mass index and extent of MRI-detected inflammation: opposite effects in rheumatoid arthritis versus other arthritides and asymptomatic persons. | 27770823 |
| Refractory anemias, Inflammation, Foot joint structure | Altered Intercellular Communication | We hypothesized that the phenomenon is caused by an inverse relationship between BMI and inflammation in hand and foot joints with RA. | 27770823 |
| Refractory anemias, Inflammation, Arthritis | Altered Intercellular Communication | To explore this hypothesis, local inflammation was measured using magnetic resonance imaging (MRI) in early arthritis patients presenting with RA or other arthritides and in asymptomatic volunteers. | 27770823 |
| Synovitis, Inflammation, Tenosynovitis, Edema of bone marrow | Altered Intercellular Communication | Each MRI scan was scored by two readers on synovitis, bone marrow edema (BME), and tenosynovitis; the sum yielded the total MRI inflammation score. | 27770823 |
| Refractory anemias, Inflammation, Arthritis | Altered Intercellular Communication | A higher BMI was associated with higher MRI inflammation scores in arthritides other than RA (b = 1.082, p < 0.001) and in asymptomatic volunteers (b = 1.029, p = 0.040), whereas it was associated with lower MRI inflammation scores in RA (b = 0.97, p = 0.005). | 27770823 |
| Inflammation, Synovitis, Refractory anemias, Arthritis, Tenosynovitis | Altered Intercellular Communication | Evaluating the different types of inflammation, a higher BMI was associated with higher synovitis, BME, and tenosynovitis scores in arthritides other than RA (respectively b = 1.084, p < 0.001, b = 1.021, p = 0.24, and b = 1.054, p = 0.003), but with lower synovitis and BME scores in RA (respectively b = 0.98, p = 0.047 and b = 0.95, p = 0.002). | 27770823 |
| Thrombotic Microangiopathies, Inflammation | Altered Intercellular Communication | Complement activation, inflammation and relative ADAMTS13 deficiency in secondary thrombotic microangiopathies. | 27771173 |
| Inflammation, 5-Trimethoxyamphetamine | Altered Intercellular Communication | Our results indicate that the secondary TMA syndrome and its poor outcome is characterized by relative ADAMTS13 deficiency, inflammation, and complement activation with consumption via the classical and alternative pathways. | 27771173 |
| Inflammation, Dental Plaque | Altered Intercellular Communication | Randomized Trial of Plaque-Identifying Toothpaste: Decreasing Plaque and Inflammation. | 27771276 |
| Inflammation, Dental Plaque | Altered Intercellular Communication | Randomized data are sparse about whether a plaque-identifying toothpaste reduces dental plaque and nonexistent for inflammation. | 27771276 |
| Inflammation, Atherosclerosis, Cardiovascular Diseases | Altered Intercellular Communication | Inflammation is intimately involved in the pathogenesis of atherosclerosis and is accurately measured by high-sensitivity C-reactive protein (hs-CRP), a sensitive marker for cardiovascular disease. | 27771276 |
| Inflammation, Cardiovascular Diseases | Altered Intercellular Communication | The observed reduction in inflammation supports the hypothesis of a reduction in risks of cardiovascular disease. | 27771276 |
| Inflammation | Altered Intercellular Communication | Histology revealed that invasive H pylori were more commonly associated with chronic inflammation, in both the antrum (15/15 chronic, 8/15 acute) and fundus (17/18 chronic, 8/18 acute). | 27771376 |
| Malnutrition, Comorbidity | Altered Intercellular Communication | Frailty Score significantly correlated with Charlson's comorbidity score (r = 0.40, p < 0.0001), Malnutrition Inflammation Score (r = 0.59, p < 0.0001), and inversely with Subjective Global Assessment score (r = -0.44, p < 0.0001). | 27771713 |
| Inflammation, Psychiatric, Data types - Address | Altered Intercellular Communication | Although we failed to find a direct relationship between AD and the genetic variants investigated, possible connections with inflammation and psychiatric symptoms were suggested. | 27772752 |
| Inflammation, Ischemic stroke | Altered Intercellular Communication | Association of TLR8 gene rs3764880 polymorphisms with susceptibility and lipid metabolism- and inflammation response-related quantitative traits of ischemic stroke in southern Chinese Han male population. | 27772795 |
| Inflammation | Altered Intercellular Communication | TLRs have an important function in inflammation and lipid metabolism. | 27772795 |
| Inflammation, Blood Clot | Altered Intercellular Communication | There were no differences in patient comorbidities; however, symptomatic patients more frequently presented with thrombus (n = 10; 67% vs n = 1; 10%; P = .01) and inflammation (n = 8; 53% vs n = 1; 10%; P = .04), and trended toward increased stenosis (n = 12; 80% vs n = 4; 40%; P = .09) compared with asymptomatic patients. | 27773728 |
| Inflammation | Altered Intercellular Communication | Among patients treated nonoperatively, no patients complained of symptoms at follow-up, and 50% of those with inflammation on initial imaging had resolution. | 27773728 |
| Inflammation, Hypertension, CTCAE | Altered Intercellular Communication | Low birth weight (LBW) has been considered as a risk factor for adult hypertension that is associated with deterioration of autonomic functions and low-grade inflammation. | 27773909 |
| Inflammation | Altered Intercellular Communication | We propose that LBW leads to blunted autonomic responses and low-grade inflammation in seemingly healthy Mongolian adults. | 27773909 |
| Amyotrophic Lateral Sclerosis, Inflammation, Nerve Degeneration | Altered Intercellular Communication | Pathophysiological mechanisms that contribute to neurodegeneration in Amyotrophic Lateral Sclerosis (ALS) include oxidative stress and inflammation. | 27774920 |
| Amyotrophic Lateral Sclerosis, Inflammation | Altered Intercellular Communication | We confirmed the systemic alteration of both the redox and the inflammation status in ALS patients, and we observed a link with some clinical parameters. | 27774920 |
| Laryngitis | Altered Intercellular Communication | Prolonged diffuse laryngeal inflammation from smoking and/or reflux is commonly diagnosed as chronic laryngitis and treated empirically with expensive drugs that have not proven effective. | 27775059 |
| Hour | Altered Intercellular Communication | Higher number of HRS, larger area of IFAF and presence of SND may indicate a prevalent inflammatory condition in DME with specific response to targeted treatment. | 27775223 |
| Inflammatory abnormality of the eye | Altered Intercellular Communication | The primary endpoint was the control of ocular inflammation. | 27775458 |
| Inflammatory abnormality of the eye | Altered Intercellular Communication | Ocular inflammation was controlled at 3 months for 80.9% of patients, at 6 months for 94.7%, at 12 months for 83.3%, and at >12 months for 86.7%. | 27775458 |
| Inflammation, Malignant Neoplasms, Diffuse Idiopathic Pulmonary Neuroendocrine Cell Hyperplasia | Altered Intercellular Communication | Diffuse Idiopathic Pulmonary Neuroendocrine Cell Hyperplasia and Granulomatous Inflammation Mimicking High-Grade Malignancy on FDG-PET/CT. | 27775945 |
| Necrotizing granulomatous inflammation, Aggressive course | Altered Intercellular Communication | We report an unusual case of DIPNECH colocalizing with necrotizing granulomatous inflammation mimicking high-grade aggressive malignancy on FDG-PET and a typical case of DIPNECH for comparison with low FDG avidity. | 27775945 |
| Inflammation, Impaired cognition, Postoperative delirium | Altered Intercellular Communication | Inflammation after cardiopulmonary bypass may contribute to postoperative delirium and cognitive dysfunction. | 27775998 |
| Inflammation, Obesity | Altered Intercellular Communication | It is also associated with markers of obesity and inflammation. | 27776152 |
| methyldopa, Inflammation, Drusen | Altered Intercellular Communication | It is established that inflammation contributes to the pathogenesis of drusen and AMD. | 27776188 |
| Inflammation, Drusen | Altered Intercellular Communication | Systemic inflammation may contribute to drusen formation in monkeys. | 27776188 |
| Inflammation, Amyloidosis | Altered Intercellular Communication | Association of brain amyloidosis with pro-inflammatory gut bacterial taxa and peripheral inflammation markers in cognitively impaired elderly. | 27776263 |
| Inflammation | Altered Intercellular Communication | AD brains feature an inflammatory reaction around amyloid plaques, and a specific subset of the gut microbiota (GMB) may promote brain inflammation. | 27776263 |
| Inflammation, Amyloidosis, Data types - Address | Altered Intercellular Communication | We investigated the possible role of the GMB in AD pathogenesis by studying the association of brain amyloidosis with (1) GMB taxa with pro- and anti-inflammatory activity; and (2) peripheral inflammation in cognitively impaired patients. | 27776263 |
| Inflammation, Amyloidosis | Altered Intercellular Communication | A possible causal relation between GMB-related inflammation and amyloidosis deserves further investigation. | 27776263 |
| Inflammation, Axonal loss, Edema | Altered Intercellular Communication | A nerve biopsy showed lymphocyte infiltration (including cytotoxic CD8 cells), oedema, marked axonal loss and myelin-positive macrophages, indicating florid inflammation. | 27776522 |
| Inflammation, Injury of kidney, Chronic Kidney Diseases, Atherosclerosis | Altered Intercellular Communication | Elevated mass and activity of Lp-PLA2 related to inflammation and atherosclerosis may take part in the development of kidney injury and atherosclerosis in patients with CKD. | 27776715 |
| Inflammation, Obesity, Diverticular Diseases | Altered Intercellular Communication | Adipose tissue secretes inflammatory cytokines, and chronic inflammation may account for the link between obesity and a more severe presentation of diverticular disease. | 27778168 |
| Inflammation, Fatty degeneration | Altered Intercellular Communication | The analysis of association with the disease severity showed that carriers of the A-allele had lower degree of histological steatosis (1.76 +- 0.83 vs. 2.19 +- 0.78, P = 0.03) and lower scores of lobular inflammation (0.54 +- 0.65 vs. 0.95 +- 0.92, P = 0.02) and NAFLD-Activity Score (2.9 +- 1.4 vs. 3.7 +- 1.4, P = 0.015) compared with noncarriers. | 27778410 |
| Fibrosis Assessment, Hepatitis | Altered Intercellular Communication | Magnetic resonance data were used to define the liver inflammation and fibrosis score (LIF 0-4). | 27778429 |
| Nonalcoholic Steatohepatitis, Inflammation, Fibrosis Assessment, Fatty degeneration, Non-alcoholic Fatty Liver Disease | Altered Intercellular Communication | Biopsies were assessed for steatosis, lobular inflammation, ballooning and fibrosis and classified as non-alcoholic steatohepatitis or simple steatosis, and mild or significant (Activity >=2 and/or Fibrosis >=2 as defined by the Fatty Liver Inhibition of Progression consortium) non-alcoholic fatty liver disease. | 27778429 |
| Fibrosis Assessment, Hepatitis | Altered Intercellular Communication | Fibrosis stage on biopsy correlated with liver inflammation and fibrosis (rs =.51, P<.0001). | 27778429 |
| Fibrosis Assessment, Hepatitis, Liver Cirrhosis | Altered Intercellular Communication | The area under the receiver operating curve using liver inflammation and fibrosis for the diagnosis of cirrhosis was 0.85. | 27778429 |
| Fibrosis Assessment, Hepatitis | Altered Intercellular Communication | Liver inflammation and fibrosis score for ballooning grades 0, 1 and 2 was 1.2, 2.7 and 3.5 respectively (P<.05) with an area under the receiver operating characteristic curve of 0.83 for the diagnosis of ballooning. | 27778429 |
| Nonalcoholic Steatohepatitis, Fibrosis Assessment, Fatty degeneration, Hepatitis | Altered Intercellular Communication | Patients with steatosis had lower liver inflammation and fibrosis (1.3) compared to patients with non-alcoholic steatohepatitis (3.0) (P<.0001); area under the receiver operating characteristic curve for the diagnosis of non-alcoholic steatohepatitis was 0.80. | 27778429 |
| Fibrosis Assessment, Non-alcoholic Fatty Liver Disease, Hepatitis | Altered Intercellular Communication | Liver inflammation and fibrosis scores for patients with mild and significant non-alcoholic fatty liver disease were 1.2 and 2.9 respectively (P<.0001). | 27778429 |
| Fibrosis Assessment, Non-alcoholic Fatty Liver Disease, Hepatitis | Altered Intercellular Communication | The area under the receiver operating characteristic curve of liver inflammation and fibrosis for the diagnosis of significant non-alcoholic fatty liver disease was 0.89. | 27778429 |
| Inflammation, Blood Vessel, Necrosis | Altered Intercellular Communication | The benefits of this treatment, however, are often accompanied with a higher risk of major complications and blood vessel damage because of radiation-induced inflammation and necrosis of the vessel wall. | 27778451 |
| Inflammation, melanoma | Altered Intercellular Communication | The molecular and cellular mechanisms behind the involvement of inflammation in melanoma have not been fully elucidated. | 27779100 |
| Inflammation, Meibomian gland dysfunction, Fibrosis Assessment, Dual-affinity B7-H3/CD3-targeted Protein MGD009, Dryness of eye | Altered Intercellular Communication | IVCM application provides a strong support to differentiate dry eye patients with different symptoms: meibomian gland dysfunction (MGD) plays a pivotal role in dry eye aggravation, and using IVCM to observe MG fibrosis, changes in size and density of MG as well as status of inflammation cells can help not only correctly diagnose the type and severity of dry eye, but also possibly prognosticate in routine eye examination in the occurrence of MGD. | 27779170 |
| Airway structure | Altered Intercellular Communication | The preservation of EPIs may have a therapeutic benefit in intractable airway inflammation, such as eosinophilic CRS. | 27779422 |
| Inflammation, Endotoxemia, Irritable Bowel Syndrome | Altered Intercellular Communication | Systemic symptoms in irritable bowel syndrome: An investigative study on the role of enterocyte disintegrity, endotoxemia and inflammation. | 27779674 |
| Inflammation, Traumatic injury | Altered Intercellular Communication | Bone marrow (BM) residing stem cells are mobilized from their BM niches into peripheral blood (PB) in several pathological situations including tissue organ injury and systemic inflammation. | 27779706 |
| Inflammation, Data types - Address | Altered Intercellular Communication | Inflammation occurs in the brains of patients with AD, and is critical for disease progression. | 27779711 |
| HD Term Type | Altered Intercellular Communication | Low lean body mass (LBM) is an indicator of malnutrition inflammation syndrome, which is common in hemodialysis (HD) patients. | 27780214 |
| Inflammatory Bowel Diseases, Gastrointestinal inflammation | Altered Intercellular Communication | These results show that microbial signals enhance the TGFb-activating ability of human DC via regulation of integrin avb8 expression, and that intestinal inflammation may drive this pathway in patients with IBD. | 27782111 |
| Inflammatory Bowel Diseases | Altered Intercellular Communication | Expression was significantly upregulated on intestinal DC from IBD patients, indicating that inflammatory signals may upregulate expression of this key TGFb-activating molecule. | 27782111 |
| Pneumonitis, Pneumonia | Altered Intercellular Communication | YKL-40, CCL18 and SP-D levels were higher in patients with more severe pneumonia, possibly reflecting the extent of pulmonary inflammation. | 27782361 |
| Intraocular inflammation, Uveitis | Altered Intercellular Communication | Clinical Patterns and Causes of Intraocular Inflammation in a Uveitis Patient Cohort from Egypt. | 27782772 |
| Intraocular inflammation, Uveitis | Altered Intercellular Communication | To analyze the patterns and causes of intraocular inflammation in patients attending uveitis referral clinics in Egypt. | 27782772 |
| Inflammation, Ulcerative Colitis | Altered Intercellular Communication | Diagnostic evaluation of appendiceal orifice inflammation in ulcerative colitis. | 27782893 |
| Inflammation, Ulcerative Colitis | Altered Intercellular Communication | To evaluate the diagnostic significance of appendiceal orifice inflammation (AOI) in ulcerative colitis (UC) patients. | 27782893 |
| Pain Distress Question, Inflammation | Altered Intercellular Communication | Overall, conditions characterised by pain and inflammation tended to show stronger associations with MDE. | 27784343 |
| Inflammation, 3,4-methylenedioxyethamphetamine, Pain Distress Question | Altered Intercellular Communication | The prevalence of MDE is elevated in association with most chronic conditions, but especially those characterised by inflammation and pain. | 27784343 |
| Inflammation, Cartilage damage | Altered Intercellular Communication | In the AIA model, cartilage damage and inflammation were also reduced in CD9-/- mice. | 27784871 |
| Inflammation, Infection | Altered Intercellular Communication | Cholinergic PET imaging in infections and inflammation using 11C-donepezil and 18F-FEOBV. | 27785538 |
| Inflammation, Carcinoma of lung, Infection | Altered Intercellular Communication | Finally, we present initial data from human patients with infections, inflammation, and renal and lung cancer. | 27785538 |
| Inflammation, Non-Small Cell Lung Carcinoma, Pneumonia | Altered Intercellular Communication | In humans, very high 11C-donepezil uptake was seen in a lobar pneumonia and in peri-tumoral inflammation surrounding a non-small cell lung carcinoma, markedly superseding the 18F-FDG uptake in the inflammation. | 27785538 |
| Inflammation | Altered Intercellular Communication | Preliminary data in humans strongly suggest that 11C-donepezil can exhibit more intense accumulation than 18F-FDG at sites of chronic inflammation. | 27785538 |
| Inflammation, Infection, Inflammatory disorder | Altered Intercellular Communication | Cholinergic PET imaging may therefore have potential applications for basic research into cholinergic mechanisms of immune modulation, but also clinical applications for diagnosing infections, inflammatory disorders, and cancer inflammation. | 27785538 |
| Inflammation, Primary malignant neoplasm, Traumatic injury, Neoplasms | Altered Intercellular Communication | Recent studies suggest that systemic inflammation induced by surgical trauma can accelerate the adhesion of circulating tumor cells to the vascular endothelium of distant organs, resulting in early cancer recurrence. | 27785660 |
| Inflammation, Disease | Altered Intercellular Communication | The inflammation markers and RA disease activity were also assessed. | 27785938 |
| Inflammation, Synovitis | Altered Intercellular Communication | The detection of synovitis by imaging was more important than disease activity and inflammation markers for assessing the progression of shoulder joint destruction. | 27785938 |
| Psoriatic Juvenile Idiopathic Arthritis, Inflammation, Psoriasis | Altered Intercellular Communication | Irisin might be a marker of inflammation in psoriatic patients, but may not be a reliable indicator of metabolic conditions, severity of psoriasis nor efficacy of antipsoriatic treatment. | 27786588 |
| Inflammatory Bowel Diseases, Crohn Disease, Gastrointestinal inflammation, Ulcerative Colitis | Altered Intercellular Communication | Crohn's disease and ulcerative colitis, collectively known as inflammatory bowel disease (IBD), are characterized by chronic inflammation of the gastrointestinal tract (1). | 27787492 |
| Inflammation, Primary malignant neoplasm, Acidosis, Fever, CTCAE | Altered Intercellular Communication | These results suggest that acting together fever and local acidosis might drive the differentiation of neutrophils into a profile able to promote both cancer progression and tissue repair during the late phase of inflammation, two processes that are strongly dependent on the local production of angiogenic factors by infiltrating immune cells. | 27787523 |
| selenium, Fibrosis Assessment, Hepatitis | Altered Intercellular Communication | SE could estimate advanced liver fibrosis without influence of liver inflammation unlike other serological liver fibrosis markers. | 27787686 |
| Inflammation, Psoriasis | Altered Intercellular Communication | Increased global arterial and subcutaneous adipose tissue inflammation in patients with moderate-to-severe psoriasis. | 27787888 |
| Inflammation, Psoriasis, Cardiovascular Diseases | Altered Intercellular Communication | Psoriasis is associated with cardiovascular disease; it has been proposed that increased cardiovascular risk is caused by low-grade systemic inflammation involving organs and tissues other than the skin and joints. | 27787888 |
| vascular inflammations, Psoriasis | Altered Intercellular Communication | To investigate signs of vascular inflammation in untreated patients with moderate-to-severe psoriasis assessed by 18 F-fluorodeoxyglucose (FDG) positron emission tomography-computed tomography. | 27787888 |
| Inflammation, Psoriasis | Altered Intercellular Communication | Arterial inflammation was increased in patients with psoriasis vs. controls (mean +- SD whole vessel TBRmax 2*46 +- 0*31 vs. 2*09 +- 0*36; P = 0*005). | 27787888 |
| Inflammation, Psoriasis | Altered Intercellular Communication | Global arterial inflammation and subcutaneous inflammation were significantly increased in patients with moderate-to-severe psoriasis compared with controls. | 27787888 |
| Inflammation, Fibrosis Assessment, Fatty degeneration, Chronic liver disease | Altered Intercellular Communication | Hepatic Fibrosis, Inflammation, and Steatosis: Influence on the MR Viscoelastic and Diffusion Parameters in Patients with Chronic Liver Disease. | 27788034 |
| Inflammation, Fibrosis Assessment, Fatty degeneration, Chronic liver disease | Altered Intercellular Communication | Purpose To determine the relationship of liver fibrosis, inflammation, and steatosis with the magnetic resonance (MR) viscoelastic and diffusion parameters in patients with chronic liver disease and to compare the diagnostic accuracy of the imaging parameters in staging liver fibrosis. | 27788034 |
| Inflammation, Fibrosis Assessment, Fatty degeneration | Altered Intercellular Communication | Fibrosis, inflammation, and steatosis were assessed with the METAVIR and steatosis, activity, and fibrosis (or SAF) scoring systems. | 27788034 |
| Inflammation, Fibrosis Assessment, Fatty degeneration | Altered Intercellular Communication | Spearman correlation and multiple regression analyses were performed to determine the relationship between liver fibrosis, inflammation, steatosis, and alanine aminotransferase (ALT) levels and viscoelastic and diffusion parameters. | 27788034 |
| Inflammation | Altered Intercellular Communication | Inflammation and ALT level were not associated with the viscoelastic or diffusion parameters. | 27788034 |
| Inflammation, Heart failure | Altered Intercellular Communication | Heart failure can be associated with inflammation but it is unclear if inflammation is directly related to hemodynamic worsening or is an independent pathway. | 27788390 |
| Inflammation, Heart failure, F8 wt Allele, Congestive heart failure | Altered Intercellular Communication | Our aim was to investigate inflammation and mechanical stress using serial measurements of biomarkers in acute and chronic heart failure with reduced ejection fraction (AHF and CHF). | 27788390 |
| Inflammation, Traumatic injury | Altered Intercellular Communication | Reg family proteins (Reg1A, 1B, 3A/G, 4) are a group of calcium-dependent lectins that promote islet growth in response to inflammation and/or injuries. | 27788482 |
| Inflammation, Retinal Artery Occlusion, Susac Syndrome, hearing impairment, Encephalopathy, CTCAE 5.0 | Altered Intercellular Communication | Susac's syndrome is characterized by inflammation and occlusion of pre-capillary arterioles with the clinical triad of branch retinal artery occlusion (BRAO), encephalopathy and hearing loss. | 27788613 |
| Idiopathic disease, Necrotizing, Sialometaplasia, Necrotizing | Altered Intercellular Communication | Necrotising sialometaplasia is a benign, necrotising, self-healing inflammatory condition categorised as idiopathic disease of salivary glands. | 27789544 |
| Inflammation | Altered Intercellular Communication | Histological examination was consistent with acute inflammation of the appendiceal stump. | 27789546 |
| Fracture, Myositis | Altered Intercellular Communication | Together, our pilot data support that exercise training alters skeletal muscle inflammation and ceramide metabolism associated with TLR signaling in older adults recovering from hip fracture surgery and may be related to improvements in muscle function recovery. | 27789770 |
| Inflammation, Fracture | Altered Intercellular Communication | These pilot data demonstrate that 3 mo of exercise training in older adults recovering from hip fracture surgery was able to mitigate skeletal muscle gene expression related to inflammation and ceramide metabolism while also improving surgical limb lean tissue, strength, and physical function. | 27789770 |
| Inflammation | Altered Intercellular Communication | Oxidative/carbonyl stress via protein carbonylation is an important factor in causing inflammation and DNA damage. | 27791204 |
| Inflammation, Disease | Altered Intercellular Communication | This results in stress-induced premature senescence (a state of irreversible growth arrest which re-enforces chronic inflammation) in gingival epithelium, which may contribute to the pathogenesis of oral diseases. | 27791204 |
| Inflammation, Communicable Diseases, Glaucoma, CTCAE, Optic Atrophy, Lens dislocation, Diabetic Retinopathy, Traumatic injury, Corneal Diseases, Exfoliation Syndrome | Altered Intercellular Communication | Exclusion criteria were history of ocular trauma or intraocular surgery, any sign of inflammation or infection, pseudoexfoliation syndrome, glaucoma, optic atrophy, diabetic retinopathy, lens dislocation, cataracta intumescens, cataracta matura, and corneal diseases. | 27791246 |
| Atherosclerotic lesion | Altered Intercellular Communication | Several studies have indicated that EVs may play a potential role in cell-to-cell communication between macrophage foam cells and vascular smooth muscle cells (VSMCs) in atherosclerotic lesion. | 27792649 |
| Inflammation, Cardiovascular Diseases | Altered Intercellular Communication | Cadmium exposure is associated with soluble urokinase plasminogen activator receptor, a circulating marker of inflammation and future cardiovascular disease. | 27792942 |
| Inflammation, Cardiovascular Diseases | Altered Intercellular Communication | Cadmium increases the risk of cardiovascular diseases, and experimental studies show that it induces inflammation. | 27792942 |
| Inflammation, atherosclerotic | Altered Intercellular Communication | Soluble urokinase-type plasminogen activator receptor (suPAR) is an emerging biomarker for cardiovascular events related to inflammation and atherosclerotic plaques. | 27792942 |
| Inflammation, Lymphohistiocytosis, Hemophagocytic, Hematological Disease | Altered Intercellular Communication | Hemophagocytic lymphohistiocytosis (HLH) is a life threatening hematological disorder associated with severe systemic inflammation caused by an uncontrolled and ineffective immune response resulting in cytokine storm. | 27793118 |
| Inflammation, Lymphoproliferative Disorders | Altered Intercellular Communication | The presence of foreign material can cause chronic inflammation that could be the stimulus for the development of a lymphoproliferative disorder. | 27793489 |
| Inflammation, Saint Lucia | Altered Intercellular Communication | Inflammation should not be targeted systematically in all patients with LC. | 27793775 |
| Inflammation, Renal tubular disorder, Atherosclerosis, MPV17 gene, Heart failure | Altered Intercellular Communication | Conclusions We discovered and replicated associations between ACR and five cardiovascular proteins involved in tubular injury, atherosclerosis, endothelial function, heart failure, inflammation, glomerulosclerosis and podocyte injury. | 27794105 |
| Rupture, Acute abdominal pain, Inflammation | Altered Intercellular Communication | The rupture occurred on the right lateral wall of the ileocecal pouch in 4 out of 5 cases and led to acute abdominal pain and inflammation. | 27794573 |
| vascular inflammations | Altered Intercellular Communication | In recent years, platelets are known to have a large variety of functions in many pathophysiological processes and their interaction with endothelial cells and leukocytes is known to play an important role in the pathophysiology of vascular inflammation. | 27795782 |
| Inflammation, physical illness, Depression, CTCAE | Altered Intercellular Communication | There is evidence that inflammation may play a role in the association between physical illness and depression. | 27796262 |
| Inflammation, Depression, CTCAE | Altered Intercellular Communication | Our aim was to compare the impact of chronic medical conditions on incidence of depression and to examine if risk of depression varies in terms of the presence and degree of inflammation. | 27796262 |
| Inflammation, Depression, CTCAE | Altered Intercellular Communication | Inflammation may be part of the pathway by which chronic physical illness leads to depression. | 27796262 |
| Inflammation, Depression, CTCAE | Altered Intercellular Communication | Future studies should examine the role of inflammation in the prevention and management of depression. | 27796262 |
| Inflammation, Thoracic aorta calcification, Cardiovascular Diseases | Altered Intercellular Communication | Thoracic aorta calcification but not inflammation is associated with increased cardiovascular disease risk: results of the CAMONA study. | 27796543 |
| Inflammation, Cyclophosphamide/Vincristine/Dacarbazine Regimen, Vascular calcification, Cardiovascular Diseases | Altered Intercellular Communication | Arterial inflammation and vascular calcification are regarded as early prognostic markers of cardiovascular disease (CVD). | 27796543 |
| Vascular calcification, Arteritis | Altered Intercellular Communication | Our findings indicate that an unfavourable CVD risk profile is associated with marked increases in vascular calcification metabolism and vascular calcium burden of the thoracic aorta, but not with arterial inflammation. | 27796543 |
| Inflammation, Cardiovascular Diseases, Collagen Diseases, Cyclophosphamide/Vincristine/Dacarbazine Regimen, Obesity | Altered Intercellular Communication | In the general population, low-grade inflammation of adipose tissue accompanies obesity and contributes to cardiovascular disease (CVD) development, but the implication of this tissue in rheumatic disease pathology is unclear. | 27796618 |
| Inflammation, Refractory anemias, Degenerative polyarthritis, Rheumatoid Arthritis, Comorbidity | Altered Intercellular Communication | Therefore, we characterized the secretory activity of subcutaneous abdominal adipose tissue (SAAT) of females with rheumatoid arthritis (RA) and osteoarthritis (OA) and searched for its relationship with intensity of systemic inflammation, body composition and comorbidity. | 27796618 |
| Degenerative polyarthritis, Inflammation | Altered Intercellular Communication | In OA, secretion of leptin and HGF positively, while adiponectin inversely, correlated with systemic inflammation markers, and the release of MIF was an independent risk factor for CVD. | 27796618 |
| Refractory anemias, Inflammation, Degenerative polyarthritis | Altered Intercellular Communication | This study reveals differences between RA and OA patients in SAAT secretory activity and suggests its different clinical impact in these diseases, characterized by high- and low-grade systemic inflammation, respectively. | 27796618 |
| Inflammation, Refractory anemias, Degenerative polyarthritis, Amyloidosis, Cachexia | Altered Intercellular Communication | In RA, SAAT may directly or via an effect on body composition contribute to amyloidosis, cachexia or CVD co-occurring, while in OA SAAT-derived adipocytokines may rather regulate intensity of systemic inflammation and redound to CVD emergence. | 27796618 |
| Sexually Transmitted Diseases, Sense of Inadequacy Scale | Altered Intercellular Communication | Sexually transmitted disease (STD), hormonal usage, previous cryotherapy and smears collected by staff were associated with inadequacy of TZ. | 27797219 |
| Hodgkin Disease | Altered Intercellular Communication | Hepatitis C Virus Associations with Non Hodgkin's Lymphoma: Insights on Inflammation/Angiogenesis and CD Markers. | 27797254 |
"
| Lymphoma, Non-Hodgkin, Communicable Diseases, Hepatitis C, RTEL1 gene | Altered Intercellular Communication | We aimed to investigate any association between hepatitis C virus (HCV) infection and non-Hodgkin's
lymphoma (NHL) in the view of cytokines that control inflammation/angiogenesis and their correlation with
certain CD markers. | 27797254 | "
| Nonalcoholic Steatohepatitis, Inflammation, Fibrosis Assessment, Fatty degeneration, Fatty Liver Disease | Altered Intercellular Communication | Chemerin mRNA did not correlate with steatosis and was negatively associated with inflammation, fibrosis and nonalcoholic steatohepatitis (NASH) score. | 27797398 |
| Inflammation, Arteriovenous fistula, Restenosis, Atherosclerosis | Altered Intercellular Communication | Inflammation is relevant in restenosis of atherosclerotic vascular diseases, but its role in dialysis arteriovenous fistula remains unknown. | 27797894 |
| Inflammation, Hypoxia | Altered Intercellular Communication | Although tissue hypoxia and inflammation are recognized as central drivers of vessel growth, relatively little is known about the process that bridges the two. | 27797960 |
| Inflammation, ovarian neoplasm, Neoplasms | Altered Intercellular Communication | Patients with low glycerophospholipids presented with more systemic inflammation (C-reactive protein and fibrinogen negatively and albumin positively correlated) but less adaptive immune cell tumor infiltration (lower tumor and immune cell PD-L1 expression), less oxygenic respiration and increased triglyceride biosynthesis in tumor cells, and lower histone expressions, correlating with higher numbers of expressed genes and more transcriptional noise, a putative neo-pluripotent tumor cell phenotype.Conclusions: Low serum phospholipids and essential amino acids are correlated with worse outcome in ovarian cancer, accompanied by a specific tumor cell phenotype. | 27797973 |
| Tumor necrosis | Altered Intercellular Communication | Plasma Inflammation Markers of the Tumor Necrosis Factor Pathway but Not C-Reactive Protein Are Associated with Processed Meat and Unprocessed Red Meat Consumption in Bavarian Adults. | 27798340 |
| Inflammation | Altered Intercellular Communication | Further research on the role of TNF pathway markers in chronic inflammation is warranted. | 27798340 |
| Inflammation, Cardiovascular Diseases | Altered Intercellular Communication | Increased levels of TNF-a and IL6 are associated with inflammation and cardiovascular disease among patients with normal kidney function. | 27798514 |
| Axonal degeneration, Inflammation, POEMS Syndrome, Polyradiculoneuropathy, Chronic Inflammatory Demyelinating | Altered Intercellular Communication | We hypothesized that nerve biopsies from patients with POEMS syndrome would have more small vessels and axonal degeneration but less inflammation than CIDP.We performed a retrospective analysis of nerve biopsies performed on "classic" CIDP and POEMS cases. | 27799073 |
| Axonal degeneration, Polyradiculoneuropathy, Chronic Inflammatory Demyelinating, Inflammation | Altered Intercellular Communication | POEMS syndrome demonstrates more axonal degeneration and epineurial neovascularization whereas CIDP has greater endoneurial inflammation and onion-bulb formation. | 27799073 |
| Inflammation, Autonomic nervous system disorders | Altered Intercellular Communication | It has been reported that sleep deprivation is associated with cardiac autonomic disorder, inflammation, and oxidative stress. | 27799236 |
| Inflammation, HIV Infections | Altered Intercellular Communication | Inflammation, Immune Activation, Immunosenescence, and Hormonal Biomarkers in the Frailty-Related Phenotype of Men With or at Risk for HIV Infection. | 27799351 |
| Hormone abnormality, Inflammation, HIV | Altered Intercellular Communication | The extent to which inflammation, immune activation/immunosenescence, and hormonal abnormalities are driven by human immunodeficiency virus (HIV) or frailty is not clear. | 27799351 |
| Inflammation, HIV Infections | Altered Intercellular Communication | Inflammation, Immune Activation, Immunosenescence, and Hormonal Biomarkers in the Frailty-Related Phenotype of Men With or at Risk for HIV Infection. | 27799351 |
| Hormone abnormality, Inflammation, HIV | Altered Intercellular Communication | The extent to which inflammation, immune activation/immunosenescence, and hormonal abnormalities are driven by human immunodeficiency virus (HIV) or frailty is not clear. | 27799351 |
| Orbital Pseudotumor | Altered Intercellular Communication | Orbital biopsy of nonspecific orbital inflammation, commonly referred to as "orbital pseudotumor," typically shows a combination of polyclonal lymphocytes, plasmocytes, leukocytes, macrophages, and variable degrees of collagen deposition. | 27799649 |
| Mucocutaneous leishmaniasis, Orbital Pseudotumor | Altered Intercellular Communication | Herein, we report a patient with a positive history of mucocutaneous leishmaniasis who presented with an orbital mass with a histological profile of idiopathic orbital inflammation. | 27799649 |
| Leishmania viannia, Orbital Pseudotumor | Altered Intercellular Communication | Immunohistochemical and molecular analysis of the orbital specimens demonstrated that the orbital inflammation was associated with the presence of antigens of Leishmania braziliensis and DNA from the parasite. | 27799649 |
| ARCN1 gene, Toxic effect, Disease | Altered Intercellular Communication | Due to the low toxicity and known compatibility of the substance, an inhalative application as an intervention strategy for humans suffering from diseases caused by neutrophilic inflammation, like COPD, had been suggested. | 27799756 |
| ARCN1 gene, Upper Respiratory Infections | Altered Intercellular Communication | The results indicate that there is a link present between upper and lower respiratory inflammation in NIR and COPD. | 27799760 |
| Inflammation | Altered Intercellular Communication | Neutrophil-lymphocyte ratio greater than 5 at diagnosis represented systemic inflammation. | 27800646 |
| Inflammation, Necrosis | Altered Intercellular Communication | The vascular media showed scant lymphocytic inflammation without necrosis. | 27801754 |
| Inflammation, Uterine Fibroids | Altered Intercellular Communication | Vessels outside of the leiomyoma showed neither fibrinoid changes nor inflammation. | 27801754 |
| Anxiety, CTCAE 3.0, Prostate Cancer Outcomes Study, Mood Disorders, Depression, CTCAE | Altered Intercellular Communication | Also, decrease in neurotransmitters, mainly NE, serotonin and dopamine (DA) attributes to mood disorders like depression and anxiety in PCOS. | 27802175 |
| Inflammation | Altered Intercellular Communication | We identified that oxygen exchange and CRP, a marker of acute inflammation, were the most important predictors of safe discharge. | 27803369 |
| Inflammation, Myocardial, Cardiac sarcoidosis | Altered Intercellular Communication | Regional myocardial damage and active inflammation in patients with cardiac sarcoidosis detected by non-invasive multi-modal imaging. | 27804054 |
| Myocarditis | Altered Intercellular Communication | Regions with a higher SUVmax indicating active myocardial inflammation were mainly located in areas with LGE, where BMIPP and TL mismatches were evident in patients with CS. | 27804054 |
| Inflammation, Coronary heart disease | Altered Intercellular Communication | The development of several life-long diseases, such as coronary heart disease, is affected by low-grade systemic inflammation. | 27804311 |
| Typhlitis, Malignant Neoplasms | Altered Intercellular Communication | These PET/CT findings are most consistent with methotrexate-induced thecal inflammation, which needs to be distinguished from intrathecal malignancy. | 27805919 |
| Aneuploidy, Inflammation, FBN2 wt Allele | Altered Intercellular Communication | Advanced ERC findings, male gender, suspicious BC, aneuploidy in flow cytometry, inflammation, and elevation of ALP, bilirubin, ALT, AST, GGT, CEA and CA19-9 represented significant risk factors for CCA in univariate analysis. | 27806633 |
| Bile Duct Diseases, Inflammation, FBN2 wt Allele, Elevated liver enzymes | Altered Intercellular Communication | PSC patients with advanced bile duct disease and elevated liver enzymes, CEA or CA19-9, inflammation or suspicious BC are most likely to develop CCA. | 27806633 |
| Inflammation, Dysplasia, Primary malignant neoplasm | Altered Intercellular Communication | We identified four potential biomarkers from an inflammation (IL1b)-dependent mouse model of Barrett esophagus and tested them in 189 patients with Barrett esophagus with and without high-grade dysplasia (HGD)/early cancer (T1). | 27807078 |
| Stomach Carcinoma | Altered Intercellular Communication | The Preoperative Frailty Versus Inflammation-Based Prognostic Score: Which is Better as an Objective Predictor for Gastric Cancer Patients 80 Years and Older? | 27807726 |
| Inflammation | Altered Intercellular Communication | Activin A is a pleiotropic cytokine holding a fundamental role in inflammation and tissue remodelling. | 27807906 |
| Inflammation | Altered Intercellular Communication | The inflammation of neurons causes release of various inflammatory mediators (IFNs, EGF, IL5, IL6, HGF, LIF and BMP2). | 27808010 |
| airway disease, Inflammation, Asthma | Altered Intercellular Communication | We conclude that variations in ASM ER expression profiles occur with inflammation and that ER variants could contribute to estrogen signaling in airway diseases such as asthma. | 27808402 |
| Kidney Failure, Chronic, Inflammation, Dysautonomia, Familial | Altered Intercellular Communication | Association between autonomic nervous dysfunction and cellular inflammation in end-stage renal disease. | 27809785 |
| HD Term Type, Inflammation | Altered Intercellular Communication | We intended to confirm a role of autonomous dysregulation for inflammation in HD patients. | 27809785 |
| Inflammation | Altered Intercellular Communication | Patients suffered from chronic inflammation (CRP 9.4 [12.9] mg/l, controls 1.6 [2.4] mg/l, p < 0.001) and expanded proinflammatory monocyte subpopulations (CD14++/CD16+ cells: patients 41 [27]/ml, controls 24 [18]/ml, p < 0.01). | 27809785 |
| Inflammation, Muscle damage | Altered Intercellular Communication | Independent predictors of elevation in the levels of markers of inflammation and muscle damage were determined by a multivariate linear regression model. | 27810151 |
| Inflammation | Altered Intercellular Communication | In the absence of cerebrospinal fluid (CSF) abnormality, systemic inflammation did not affect the CSF/serum albumin ratio. | 27810376 |
| Inflammation, Abnormality of the cerebrospinal fluid | Altered Intercellular Communication | When CSF abnormality was present, systemic inflammation significantly predicted the CSF/serum albumin ratio. | 27810376 |
| Inflammation | Altered Intercellular Communication | In conclusion, the diseased BBB has an increased susceptibility to systemic inflammation. | 27810376 |
| Bladder polyp, Inflammation, Schistosomiasis | Altered Intercellular Communication | Bladder polyps due to schistosomiasis represent a rare condition in developed countries and have to be ruled out in the case of any intense unexplained inflammation. | 27810520 |
| Inflammation, diabetic | Altered Intercellular Communication | The mitochondria-targeted antioxidant MitoQ modulates oxidative stress, inflammation and leukocyte-endothelium interactions in leukocytes isolated from type 2 diabetic patients. | 27810734 |
| Inflammation | Altered Intercellular Communication | Clinical significance of GCF sIL-6R and calprotectin to evaluate the periodontal inflammation. | 27810997 |
| Inflammation | Altered Intercellular Communication | Conclusions Both gingival crevicular fluid sIL-6R and calprotectin concentrations are significant biomarkers in the evaluation of periodontal inflammation. | 27810997 |
| Inflammation, S100A4 protein, human | Altered Intercellular Communication | IL-1b is an essential factor of inflammation initiation, and it also promotes malignant transformation, indicating its tumorigenic property. | 27811377 |
| Inflammation, Cardiomyopathies | Altered Intercellular Communication | Macrophage migration inhibitory factor (MIF) promotes inflammation and is an important factor in uremic cardiomyopathy. | 27811451 |
| methyldopa, Inflammation | Altered Intercellular Communication | Although the exact pathogenic mechanism of AMD is still unknown, clinical observations such as the high accumulation of oxidative products and macrophages in retina suggest the importance of oxidative stress and inflammation in AMD. | 27812755 |
| Inflammation, Tacca leontopetaloides, Cerebrovascular accident | Altered Intercellular Communication | Background History of stroke symptoms in the absence of prior diagnosed stroke or transient ischemic attack (TIA) is associated with future stroke risk, as are biomarkers of inflammation, cardiac function and hemostasis. | 27813265 |
| Rheumatoid Arthritis, Fibrosis Assessment, Myocarditis | Altered Intercellular Communication | Magnetic Resonance Imaging-Detected Myocardial Inflammation and Fibrosis in Rheumatoid Arthritis: Associations With Disease Characteristics and N-Terminal Pro-Brain Natriuretic Peptide Levels. | 27813364 |
| Disease | Altered Intercellular Communication | These data suggest that cardiac MRI findings indicating myocardial inflammation/fibrosis are correlated with RA disease activity and alterations in myocardial structure known to precede clinical HF. | 27813364 |
| Pancreatitis, Choroidal and Ciliary Body Melanoma pT1d TNM Finding v8 | Altered Intercellular Communication | PDG cell replication was increased in T1D (6.3% +- 1.6% vs 0.6% +- 0.1%, P < 0.001, T1D vs nondiabetic), most prominently in association with pancreatic inflammation. | 27813705 |
| Inflammation, Pancreatitis due to pancreatic duct obstruction, Intraductal Hyperplasia, Atrophy of pancreas, Choroidal and Ciliary Body Melanoma pT1d TNM Finding v8 | Altered Intercellular Communication | The PDG compartment is activated in T1D consistent with a response to ongoing inflammation, and via resulting ductal hyperplasia may contribute to local obstructive pancreatitis and eventual pancreatic atrophy characteristic of T1D. | 27813705 |
| Inflammation, Neoplasms | Altered Intercellular Communication | Other biomarkers reflect the inflammation and tumor burden like high-sensitivity C-reactive protein(hs-CRP) and urine free light chain were also detected. | 27814274 |
| Multiple Myeloma, Inflammation, Injury of kidney, Neoplasms | Altered Intercellular Communication | And it could be considered an independent predictor of renal injury from multiple myeloma reflecting active kidney damage, tumor burden, and inflammation. | 27814274 |
| Inflammation, Endothelial dysfunction, Atherosclerosis | Altered Intercellular Communication | Human cartilage glycoprotein-39 (YKL-40) has been suggested to be a new marker of inflammation, atherosclerosis, and endothelial dysfunction. | 27815265 |
| Inflammation, Uveitis | Altered Intercellular Communication | The construct "uveitis inflammatory activity" was defined as any intraocular inflammation that included external structures (cornea) in addition to uvea. | 27815703 |
| Inflammation, Papilledema, Edema, Vitreous haze, Hypopyon, vascular inflammations | Altered Intercellular Communication | Seven domains and 15 items were identified: best-corrected visual acuity, inflammation of the anterior chamber (anterior chamber cells, hypopyon, the presence of fibrin, active posterior keratic precipitates and iris nodules), intraocular pressure, inflammation of the vitreous cavity (vitreous haze, snowballs and snowbanks), central macular edema, inflammation of the posterior pole (the presence and number of choroidal/retinal lesions, vascular inflammation and papillitis), and global assessment from both (patient and physician). | 27815703 |
| Delirium, Inflammation, Ischemic stroke | Altered Intercellular Communication | Our aim was to determine whether there is an entity relationship between delirium, inflammation and acute ischemic stroke (AIS). | 27816188 |
| Inflammation | Altered Intercellular Communication | As early as 1-week post-ischemia, an increased number of newborn cells in the subventricular zone and a reduced number of activated microglial cells in the peri-infarct area were observed in the UCB-PL group, suggesting that enhanced neurogenesis and/or the suppression of inflammation may have contributed to functional protection/recovery. | 27816964 |
| Inflammation, Neoplasms | Altered Intercellular Communication | Late compared with early imaging was better able to distinguish between malignant and benign tissue [W3, SUVmean: tumour vs. BPH 2.5 vs. 2.0 (p<0.001), tumour vs. inflammation 2.5 vs. 1.7 (p<0.001), tumour vs. healthy tissue 2.5 vs. 2.0 (p<0.001); W1, SUVmean: tumour vs. BPH 3.1 vs. 3.1 (p=0.771), tumour vs inflammation 3.1 vs. 2.2 (p=0.021), tumour vs. healthy tissue 3.1 vs. 2.5 (p<0.001)] as well as between high-grade and low/intermediate-grade tumours (W3, SUVmean: 2.6 vs. 2.1 (p=0.040); W1, SUVmean: 3.1 vs. 2.8 (p=0.173)). | 27817158 |
| Inflammation, Neoplastic Cell Transformation | Altered Intercellular Communication | Rac1-Mediated DNA Damage and Inflammation Promote Nf2 Tumorigenesis but Also Limit Cell-Cycle Progression. | 27818180 |
| Inflammation, Colorectal Carcinoma | Altered Intercellular Communication | Decreased preoperative serum 25-Hydroxyvitamin D levels in colorectal cancer are associated with systemic inflammation and serrated morphology. | 27819306 |
| Inflammation, Atherosclerosis, Communicable Diseases, Chlamydia, HIV | Altered Intercellular Communication | In the last decade, several infectious agents rather than any single pathogen, including Chlamydia pneumoniae and human immunodeficiency virus (HIV), have been shown to contribute to the development of atherosclerosis and subsequent cardiovascular events by inducing systemic inflammation and/or acting directly on the vascular wall. | 27819396 |
| Uremia, Inflammation, Malnutrition, Infection | Altered Intercellular Communication | Haemodialysis patients are at greater risk of infections than individuals not on dialysis due to their immunosuppressive state caused by several factors (uraemia, vascular access, inflammation, malnutrition). | 27819399 |
| Inflammation, Schizophrenia | Altered Intercellular Communication | Since growing evidence suggests a significant role of chronic low-grade inflammation in the physiopathology of schizophrenia, we have hypothesized that functional genetic variant of the IFN gamma (IFN-g; +874A/T; rs2430561) gene may be involved in the predisposition to schizophrenia. | 27819519 |
| Inflammation | Altered Intercellular Communication | 18F-FDG Imaging of Chronic Inflammation Associated With Promontofixation of the Uterus. | 27819855 |
| Inflammation | Altered Intercellular Communication | Promontofixation can be associated with complications due to chronic inflammation. | 27819855 |
| Inflammation | Altered Intercellular Communication | F-FDG-PET may diagnose chronic inflammation of the mesh. | 27819855 |
| Trachoma , Perifolliculitis | Altered Intercellular Communication | To complete the baseline trachoma map in Oromia, Ethiopia, by determining prevalences of trichiasis and trachomatous inflammation - follicular (TF) at evaluation unit (EU) level, covering all districts (woredas) without current prevalence data or active control programs, and to identify factors associated with disease. | 27820657 |
| Inflammation, Fibrosis Assessment | Altered Intercellular Communication | It is assosiciated with two step hit scenario; the first step is fat accumulationin liver and in the second step inflammation and fibrosis are the major compenents. | 27821024 |
| Allergic sensitization, Inflammation, "Extra-osseous Ewings sarcoma | Altered Intercellular Communication | Although its pathogenesis remains poorly understood, there is strong evidence that the eosinophilic inflammation in EoE is primarily triggered by immune dysregulation secondary to allergic sensitization to dietary or aero-allergens. | 27821174 |
| Inflammation, ETV3 wt Allele | Altered Intercellular Communication | Serum HDL-c levels were the major determinant of the associations between serum hs-CRP levels and MetS and the key link between inflammation and MetS. | 27822025 |
| Refractory anemias, Rheumatoid Arthritis, destruction joint, Inflammation | Altered Intercellular Communication | Rheumatoid arthritis (RA) appears as inflammation of synovial tissue and joint destruction. | 27822475 |
| Inflammation, Chronic heart failure, Congestive heart failure | Altered Intercellular Communication | Inflammation plays a crucial role in the progression of chronic heart failure (CHF). | 27822484 |
| Colorectal Carcinoma | Altered Intercellular Communication | A Postoperative Systemic Inflammation Score Predicts Short- and Long-Term Outcomes in Patients Undergoing Surgery for Colorectal Cancer. | 27822634 |
| Systemic Inflammatory Response Syndrome, Communicable Diseases, Inflammation | Altered Intercellular Communication | Our aim was to compare the area under the receiver operating curve (AUROC), sensitivity, specificity, and likelihood ratios of qSOFA vs. systemic inflammation response syndrome (SIRS) in predicting in-hospital mortality among emergency department (ED) patients with suspected infection admitted to intensive care units (ICUs). | 27823893 |
| Inflammation, Prostate carcinoma | Altered Intercellular Communication | Systemic inflammation and immune responses are reported to be associated with progressive prostate cancer. | 27823973 |
| Non-Small Cell Lung Carcinoma | Altered Intercellular Communication | To investigate the association between C-reactive protein/albumin ratio (CAR), an inflammation-based prognostic score, and clinicopathological factors, as well as its association with long-term outcomes in patients with operable non-small cell lung cancer (NSCLC). | 27823974 |
| Inflammatory Bowel Diseases, Inflammation, Ulcerative Colitis | Altered Intercellular Communication | We aimed to search new probiotic candidates for inflammatory bowel disease through translational research by analysis of ulcerative colitis (UC) patients' intestinal microbiota and clarify the effects of them on inflammation. | 27824645 |
| Inflammation, Ulcerative Colitis | Altered Intercellular Communication | We analyzed the association of F. saccharivorans to UC patients' activity and inflammation for the first time. | 27824645 |
| Gastrointestinal inflammation, Ulcerative Colitis | Altered Intercellular Communication | F. saccharivorans decreased in correlation to UC activity and suppresses intestinal inflammation. | 27824645 |
| Inflammation, HIV Infections | Altered Intercellular Communication | Do Biomarkers of Inflammation, Monocyte Activation, and Altered Coagulation Explain Excess Mortality Between HIV Infected and Uninfected People? | 27824677 |
| Inflammation, HIV Infections | Altered Intercellular Communication | HIV infection and biomarkers of inflammation [measured by interleukin-6 (IL-6)], monocyte activation [soluble CD14 (sCD14)], and coagulation (D-dimer) are associated with morbidity and mortality. | 27824677 |
| Inflammation, Intestinal Diseases | Altered Intercellular Communication | Environmental enteropathy (EE) is a poorly understood condition that refers to chronic alterations in intestinal permeability, absorption, and inflammation, which mainly affects young children in resource-limited settings. | 27824883 |
| Inflammation, Cocaine-Related Disorders | Altered Intercellular Communication | Elevated levels of C-reactive protein (CRP, determined by a high-sensitivity assay) indicate low-grade inflammation which is implicated in many age-related disorders. | 27824951 |
| Inflammation, Colorectal Carcinoma | Altered Intercellular Communication | inflammation), while ten had polyps/adenomas and seven a hitherto undiagnosed colorectal cancer. | 27824964 |
| Communicable Diseases, Unknown (origin) (qualifier value), Pericarditis, CTCAE, Inflammation | Altered Intercellular Communication | Historically the most common causes of pericarditis necessitating pericardiectomy are infection, radiation, idiopathic causes, and inflammation. | 27825685 |
| Inflammation | Altered Intercellular Communication | Patients with moderate to severe plaque-type psoriasis had active systemic inflammation, which was demonstrated by increased levels of C-reactive protein. | 27828628 |
| Inflammation, Skin lesion | Altered Intercellular Communication | Phototherapy healed the psoriatic skin lesions and reduced inflammation, while decreasing C-reactive protein levels. | 27828628 |
| Neoplasms | Altered Intercellular Communication | Nine courses resulted in a total radiological tumour shrinkage and hormonal normalisation. | 27828691 |
| Pheochromocytoma, Inflammation, Swelling, Orbital Fractures | Altered Intercellular Communication | We report on a 68-year-old survivor of pheochromocytoma multisystem crisis, whose clinical course was triggered inadvertently by a short innocuous course of oral dexamethasone to suppress inflammation and swelling after a left orbital floor fracture repair. | 27828782 |
| Inflammation | Altered Intercellular Communication | Red cell distribution width (RDW) is linked to cardiovascular risk in the general population, an association that might be driven by inflammation. | 27828877 |
| Inflammatory infiltrate, Thyroid associated opthalmopathies, Myositis, CTCAE 5.0, Orbital Pseudotumor, Vascular anomaly, Central neuroblastoma | Altered Intercellular Communication | An evaluation for thyroid eye disease, idiopathic orbital inflammation, myositis, inflammatory and neoplastic infiltration of the muscle, vascular anomalies, and metastatic neuroblastoma was unrevealing. | 27828922 |
| Inflammation, Fibrosis Assessment, Infiltration | Altered Intercellular Communication | Biopsy of the muscle revealed normal architecture with an absence of inflammation, infiltration, or fibrosis. | 27828922 |
| Sepsis, Inflammation | Altered Intercellular Communication | Epidural block decreases inflammation and oxidative stress in experimental models of sepsis as well as after surgery. | 27829181 |
| Inflammation, Coronary heart disease | Altered Intercellular Communication | These findings suggest that, in the context of severe adversity, a trait-like tendency towards greater relative right prefrontal activity may predispose to low-grade inflammation, a risk factor for conditions with inflammatory underpinnings such as coronary heart disease. | 27829190 |
| Intraocular inflammation, Irritation, Traumatic aniridia | Altered Intercellular Communication | In this case report, we describe the case of a 49 year old, male construction worker with traumatic aniridia who experienced chronic, recurrent low-grade intraocular inflammation and irritation for months after implantation of the Ophtec 311 prosthetic iris. | 27829389 |
| Intraocular inflammation, Endophthalmitis, CTCAE, Traumatic aniridia | Altered Intercellular Communication | Chronic, post-operative endophthalmitis may be a difficult to identify in the context of traumatic aniridia and iris prosthesis implantation due to other potential etiologies of chronic intraocular inflammation such as implant-induced chafing. | 27829389 |
| Intraocular inflammation, Endophthalmitis, CTCAE | Altered Intercellular Communication | Clinicians should suspect chronic, post-operative endophthalmitis in any case of recurrent, low-grade intraocular inflammation. | 27829389 |
| Refractory anemias, Inflammation | Altered Intercellular Communication | In conclusion, YY1 plays a critical role in promoting IL-6 transcription in RA which contribute to the inflammation of RA via stimulation of Th17 differentiation. | 27829535 |
| Refractory anemias, Inflammation | Altered Intercellular Communication | Thus, YY1 is likely a key molecule involved in the inflammation process of RA. | 27829535 |
| Inflammation, Coronary Artery Disease, Diabetes Mellitus, Non-Insulin-Dependent | Altered Intercellular Communication | Type 2 diabetes mellitus (T2DM) and coronary artery disease (CAD) are both characterized by chronic low-grade inflammation. | 27829708 |
| Hyperglycemia, Inflammation, Diabetes Mellitus | Altered Intercellular Communication | Hyperglycaemia inhibits REG3A expression to exacerbate TLR3-mediated skin inflammation in diabetes. | 27830702 |
| Inflammation, Injury of integument | Altered Intercellular Communication | Here we show that the antimicrobial protein REG3A controls TLR3-mediated inflammation after skin injury. | 27830702 |
| Inflammation | Altered Intercellular Communication | To our knowledge, these findings show for the first time that REG3A can modulate specific cutaneous inflammatory responses and that the decrease in cutaneous REG3A exacerbates inflammation in diabetic skin wounds. | 27830702 |
| Airway structure, Asthma | Altered Intercellular Communication | Sphingolipid (SL) metabolites have been suggested to be important inflammatory mediators in airway inflammation and asthma. | 27830727 |
| Shock, Inflammation, Chronic prostatitis, Erectile dysfunction | Altered Intercellular Communication | Heat shock protein 9-mediated inflammation reaction in patients with chronic prostatitis with erectile dysfunction. | 27831659 |
| Inflammation, Heat-Shock Response, Chronic prostatitis, Erectile dysfunction | Altered Intercellular Communication | To investigate the role of heat shock protein (HSP)-9 on the inflammation reaction present in patients with chronic prostatitis with erectile dysfunction (ED). | 27831659 |
| Inflammation, Chronic prostatitis | Altered Intercellular Communication | Furthermore, the IIEF-5 scores in the group A were also significantly higher than those in the group C. The serum levels of HSP-9, CRP, TNF-a, IL-6 and CD3 in the sera of patients with chronic prostatitis with ED were clearly increased, reflecting a high degree of inflammation which may be related to the clinical manifestations in patients with chronic prostatitis and ED. | 27831659 |
| Airway structure | Altered Intercellular Communication | Secondary outcomes included measures of oxidative stress and airway inflammation, and pulmonary function tests. | 27832073 |
| Refractory anemias, Rheumatoid Arthritis, Inflammation | Altered Intercellular Communication | Clinical remission in some patients with rheumatoid arthritis (RA) may be associated with ongoing synovial inflammation that is not always detectable on clinical examination or reflected by laboratory tests but can be visualized by musculoskeletal ultrasound. | 27832086 |
| Inflammation | Altered Intercellular Communication | Residual synovial inflammation was found in 58-67% of the patients who fulfilled at least one set of clinical remission criteria. | 27832086 |
| Inflammation | Altered Intercellular Communication | Calprotectin levels were significantly higher in patients with residual synovial inflammation than in those with ultrasound-defined remission (mean 2.5+-1.3 vs. 1.7+-0.8 mg/mL, p<0.005). | 27832086 |
| Inflammation, Congenital Abnormality | Altered Intercellular Communication | We report a case of a 39-year-old man in whom an extensive MRI with fluid-sensitive imaging sequences covering the whole of the scapula was beneficial in diagnosing the inflammation adjacent to the bony deformity, which confirmed the etiology of scapular dyskinesis. | 27832291 |
| Inflammation | Altered Intercellular Communication | Furthermore, in a 41-year old man without any anatomical variances, a similar MRI showed inflammation at the subscapular fossa that suggested altered scapular kinematics. | 27832291 |
| Inflammation | Altered Intercellular Communication | Fluid-sensitive MR images are important in defining the presence of inflammation, and are beneficial in determining the pathological significance of findings through other diagnostic measures. | 27832291 |
| Inflammation, Dysplasia, Stomach Carcinoma, Infection caused by Helicobacter pylori, Bile Reflux, Gastritis, Atrophic, Gastric Ulcer, CTCAE 5, Intestinal metaplasia | Altered Intercellular Communication | The incidence of intestinal metaplasia differed significantly in 17 municipal areas ranging from 16.79 to 38.56% and was positively correlated with the age range of 40-70 years, male gender, gastric ulcer, bile reflux, Helicobacter pylori infection, atrophic gastritis, dysplasia, gastric cancer, degree of chronic and acute inflammation, and gross domestic product per capita (P < 0.01). | 27832356 |
| Inflammation, Infection caused by Helicobacter pylori, Bile Reflux, Gastric Ulcer, CTCAE 5, Intestinal metaplasia | Altered Intercellular Communication | This study confirms age, male gender, gastric ulcer, bile reflux, H. pylori infection, severe degree of chronic and acute inflammation to be the risk factors for intestinal metaplasia. | 27832356 |
| Inflammation, Hypoxia, Atherosclerosis | Altered Intercellular Communication | CD73 (also known as ecto-5'-nucleotidase) is a key regulator of cell signaling in response to inflammation and hypoxia, and may be important in the development of atherosclerosis. | 27832456 |
| Inflammation, Bacterial resistance, Obstruction, Stasis | Altered Intercellular Communication | Obstruction in these patients may lead to bacterial overgrowth with stasis and inflammation of the colon. | 27832696 |
| Inflammation, Chronic Kidney Diseases | Altered Intercellular Communication | Tryptophan metabolism, its relation to inflammation and stress markers and association with psychological and cognitive functioning: Tasmanian Chronic Kidney Disease pilot study. | 27832762 |
| Inflammation, Chronic Kidney Diseases | Altered Intercellular Communication | Adults with chronic kidney disease (CKD) exhibit alterations in tryptophan metabolism, mainly via the kynurenine pathway, due to higher enzymatic activity induced mainly by inflammation. | 27832762 |
| Inflammation, Chronic Kidney Diseases | Altered Intercellular Communication | Indoles produced by gut-microflora are another group of tryptophan metabolites related to inflammation and conditions accompanying CKD. | 27832762 |
| Inflammation | Altered Intercellular Communication | These organized collections of immune cells have important pathophysiologic action including cytokine production leading to inflammation as well as enzymatic conversion of cholecalciferol to calcitriol via 1-a hydroxylase. | 27832822 |
| Inflammation, Fibrosis Assessment, Hepatitis | Altered Intercellular Communication | We found that the severity degree of the portal inflammation was in direct relation to the hepatitis activity index (HAI) and to the degree of fibrosis. | 27833969 |
| Inflammation, Fibrosis Assessment | Altered Intercellular Communication | The portal inflammation is dependent to the degree of fibrosis. | 27833969 |
| Inflammation, Fibrosis Assessment | Altered Intercellular Communication | The degree of inflammation significantly changes the distribution of cases with different degrees of fibrosis (chi-square p=0.00011 <0.001). | 27833969 |
| Inflammation, Fibrosis Assessment, Necrosis | Altered Intercellular Communication | Periportal inflammation, periportal necrosis and focal necrosis are the morphological aspects of the necroinflammatory process best correlated to the occurrence and development of fibrosis. | 27833969 |
| Gastrointestinal inflammation | Altered Intercellular Communication | FC directly reflects the intestinal inflammation status of a patient, and can aid in interpreting the current guidelines, which requires the integration of indirect laboratory parameters. | 27834066 |
| Inflammation, Refractory anemias, Spondylarthritis, Tooth Loss, Tooth structure | Altered Intercellular Communication | Tooth loss was common, but actual number of teeth lost, cavity occurrence, average and maximum lingual and buccal depth of space between tooth and bone, periosteal reaction, serpentine grooving surrounding teeth (considered a sign of inflammation), abscess formation, and root exposure (penetration of bone surface) were indistinguishable among controls and individuals with RA, spondyloarthropathy, and CPPD. | 27834119 |
| Inflammation, Prostate carcinoma | Altered Intercellular Communication | Intraprostatic chronic inflammation is associated with a reduced risk of prostate cancer in patients elected to a first random biopsy set. | 27834470 |
| Inflammation, Structure of posterior cerebral artery | Altered Intercellular Communication | Advanced basic science research is warranted to investigate and develop the controversial topic of intraprostatic chronic inflammation in relation to PCa. | 27834470 |
| Degenerative polyarthritis, Inflammation | Altered Intercellular Communication | Serum IL-17F and IL-23 predicted increased knee BML scores in females only, suggesting that inflammation is involved in BML pathogenesis in knee OA, especially in women. | 27836676 |
| Inflammation | Altered Intercellular Communication | These cells could contribute to inflammation by induction of T cell responses and the production of proinflammatory cytokines. | 27837111 |
| Inflammation, Synovitis, palladium, Refractory anemias, Lupus Erythematosus, Systemic | Altered Intercellular Communication | When we investigated the intensity of US findings, the joint synovitis score (GS + PD) per affected joint was lower in SLE than RA (2.0 versus 2.6, p = 0.019), while tendon inflammation score was not significantly different (2.1 versus 2.2, p = 0.738). | 27837198 |
| Refractory anemias, Inflammation, Arthropathy, Synovitis | Altered Intercellular Communication | Thus, as compared with RA, SLE arthropathy is characterized by the predominance of tenosynovitis/periextensor tendon inflammation, which is likely to develop independently from joint synovitis. | 27837198 |
| Parkinson Disease, Inflammation, Nerve Degeneration | Altered Intercellular Communication | It has been hypothesized that chronic inflammation may play an important role in the development and progression of the neurodegeneration of Idiopathic Parkinson's disease (IPD). | 27837368 |
| Inflammation | Altered Intercellular Communication | Neutrophil-lymphocyte ratio (NLR) is a marker that indicates the peripheral inflammation. | 27837368 |
| Inflammation, Nerve Degeneration | Altered Intercellular Communication | This result suggests that cerebral inflammation is in the forefront in the development of neurodegeneration in IPD, and that more evidence is needed for the role of peripheral inflammation in the development progression of disease. | 27837368 |
| Airway structure, Sleep Apnea, Obstructive | Altered Intercellular Communication | Nasal nitric oxide improved by continuous positive airway pressure therapy for upper airway inflammation in obstructive sleep apnea. | 27837378 |
| Airway structure, Sleep Apnea, Obstructive, Osage language | Altered Intercellular Communication | In this report, we examined the association between obstructive sleep apnea (OSA) and upper and lower airway inflammation based on nitric oxide (NO) measurements. | 27837378 |
| Airway structure | Altered Intercellular Communication | Airway inflammation was noninvasively analyzed by the measurement of nasally and orally exhaled NO; nasal value was presented as nasally exhaled NO minus orally exhaled NO. | 27837378 |
| Airway structure, Osage language | Altered Intercellular Communication | In OSA, upper but not lower airway inflammation can be increased by repetitive collapse of the upper airway. | 27837378 |
| vascular inflammations, Obesity, Cardiovascular Diseases | Altered Intercellular Communication | Obesity may increase susceptibility to the adverse effects of PM exposure, exacerbating the effects on cardiovascular diseases and altering the biomarkers of vascular inflammation. | 27838013 |
| Proteinuria, Arteriolar hyalinosis | Altered Intercellular Communication | Multivariate Cox proportional hazard analysis showed that the glomerular lesions, proteinuria and serum creatinine were independent risk factors for renal outcomes, while interstitial fibrosis/inflammation and arteriolar hyalinosis were not independently associated with renal outcomes in the DN group. | 27838100 |
| Inflammation, Sleep-Disordered Breathing | Altered Intercellular Communication | Markers of inflammation and oxidative stress also increased as SDB became more severe. | 27838124 |
| Inflammation, Familial Mediterranean Fever, Infection | Altered Intercellular Communication | Consecutive FMF patients in attack-free period and no other cause of intermittent inflammation including infections were recruited during their regular visits in the French reference center for FMF. | 27838405 |
| Inflammation, Dental Plaque, Atherosclerosis | Altered Intercellular Communication | The architectural transcription factor high-mobility-group AT-hook 1 (HMGA1) has been involved in atherosclerosis, plaque formation, inflammation, and in the pathogenesis of insulin resistance and T2DM. | 27839822 |
| Inflammation, Primary malignant neoplasm, Neoplasms | Altered Intercellular Communication | Inflammation accelerates tumor growth followed by reduced survival in patients with cancer. | 27839896 |
| Inflammation, Primary malignant neoplasm | Altered Intercellular Communication | Our study indicates that extraosseous Gaucheromas are comprised of cellular elements with characteristics of tumor-associated macrophages, the major players in cancer related inflammation. | 27839983 |
| Inflammation, Schizophrenia | Altered Intercellular Communication | Inflammation in Schizophrenia: Cytokine Levels and Their Relationships to Demographic and Clinical Variables. | 27840055 |
| Inflammation, Schizophrenia | Altered Intercellular Communication | Inflammation may play a role in the accelerated physical aging reported in schizophrenia, though biomarker findings and associations with demographic and clinical factors are inconsistent. | 27840055 |
| Inflammation | Altered Intercellular Communication | In addition, functional group analysis demonstrated that the up-regulated genes in smaller RIAs mainly participated in the cellular response to metal ions and inorganic substances, while most of the up-regulated genes in larger UIAs were involved in inflammation and extracellular matrix (ECM) organization. | 27841008 |
| Inflammation | Altered Intercellular Communication | Moreover, compared with control arteries, inflammation was up-regulated and muscle-related biological processes were down-regulated in both smaller RIAs and larger UIAs. | 27841008 |
| Inflammation, Rupture | Altered Intercellular Communication | In addition, the healing process, involving inflammation and ECM organization, may protect IAs from rupture. | 27841008 |
| Lymphoid hyperplasia | Altered Intercellular Communication | Approximately 93.5% (29/31) of lymphoid hyperplasia appeared as the type II microvessel pattern under NBI endoscopy, whereas 96.2% (51/53) of nasopharyngeal radiation-induced inflammation exhibited the type III or IV microvessel pattern. | 27841051 |
| Intraocular inflammation | Altered Intercellular Communication | After a course of systemic therapy, intraocular inflammation subsided but visual acuity remained poor. | 27842200 |
| Inflammation, Sleep Apnea, Obstructive, Chronic Kidney Diseases | Altered Intercellular Communication | Obstructive sleep apnea syndrome (OSAS) is associated with systemic inflammation and increased risk of cardiovascular and chronic kidney disease. | 27843647 |
| Arthralgia, Inflammation, Fever, CTCAE, Infection | Altered Intercellular Communication | The affected pathways in our study correlate well with the clinical manifestation like fever, inflammation, energy deprivation and joint pain during the infections. | 27845374 |
| nervous system disorder, Inflammation | Altered Intercellular Communication | Furthermore, several neurological diseases which cause central nervous system inflammation or degeneration were related to BP, and the association was strongest between MS and BP. | 27845416 |
| Inflammation | Altered Intercellular Communication | Interestingly, the Sod1-/- mice showed higher levels of circulating cytokines than WT mice, suggesting that the accelerated aging phenotype shown by the Sod1-/- mice could result from increased inflammation arising from an accelerated accumulation of senescent cells. | 27846439 |
| Inflammation | Altered Intercellular Communication | The accumulation of senescent cells in turn leads to increased inflammation, which plays a major role in the loss of function and increased pathology that are hallmark features of aging. | 27846439 |
| Inflammation, Fibrosis Assessment, Necrosis | Altered Intercellular Communication | Findings which predicted fibrosis progression, were baseline total inflammation (odds ratio 1.7, 95% CI 1.01-2.8), cumulative total inflammation (1.8, 95% CI 1.01-3.2, rosette formation (2.8, 95% CI 1.1-7.1), absence of pericholangitis (0.4, 95% CI 0.1-1.0) and necrosis (1.4, 95% CI 1.0-2.0). | 27846740 |
| Inflammation, Cholestasis, Liver Cirrhosis, Necrosis | Altered Intercellular Communication | Risk factors for the development of cirrhosis were cholestasis (4.6, 95% CI 1.2-16.9), interphase inflammation (3.4, 95% CI 1.1-10.4), and necrosis (3.3, 95% CI 1.2-9.7). | 27846740 |
| Inflammation, Necrosis | Altered Intercellular Communication | In a cumulative model, cumulative total inflammation (4.5, 95% CI 1.4-15.0), necrosis (6.7, 95% CI 1.3-34.6), or cumulative immunoglobulin G load (61.8, 95% CI 2.0-1954.3) were risk factors. | 27846740 |
| Inflammation, Necrosis, Fibrosis Assessment, Cholestasis, Liver Cirrhosis | Altered Intercellular Communication | The total cumulative inflammatory activity predicts the progression of fibrosis, whereas baseline fibrosis, interphase inflammation, cholestasis, necrosis, as well as the cumulative total inflammation and cumulative immunoglobulin G, are risk factors for cirrhosis. | 27846740 |
| Alopecia Areata, Inflammation | Altered Intercellular Communication | Alopecia areata is characterized by perifollicular/intrafollicular lymphocyte infiltration of the lower bulb and inflammation in the upper dermis. | 27846747 |
| Acute inflammation, Hypoalbuminemia | Altered Intercellular Communication | A 50 % elevated de-novo albumin synthesis rate was seen in patients with acute inflammation and marked hypoalbuminemia, while patients with marginal hypoalbuminemia before the start of surgery had a normal albumin synthesis rate. | 27846908 |
| Inflammation, Hypoalbuminemia | Altered Intercellular Communication | In acute inflammation with marked hypoalbuminemia, the transcapillary escape rate was no different from normal. | 27846908 |
| Hyperparathyroidism, Primary | Altered Intercellular Communication | Primary hyperparathyroidism is characterized by increased levels of serum calcium and parathyroid hormone. | 27847113 |
| Dental Plaque | Altered Intercellular Communication | Cap inflammation leads to higher plaque cap strain and lower cap stress: An MRI-PET/CT-based FSI modeling approach. | 27847118 |
| Inflammation, Dental Plaque | Altered Intercellular Communication | The impact of cap inflammation on plaque stress/strain and flow shear stress were investigated. | 27847118 |
| Inflammation, Dental Plaque | Altered Intercellular Communication | 18FDG-PET/CT and MRI data were acquired from 4 male patients (average age: 66) to assess plaque characteristics and inflammation. | 27847118 |
| Fibrous, Inflammation | Altered Intercellular Communication | Material stiffness for the fibrous cap was adjusted lower to reflect cap weakening causing by inflammation. | 27847118 |
| Hypertension, CTCAE | Altered Intercellular Communication | Cap inflammation may lead to large cap strain conditions when combined with thin cap and hypertension. | 27847118 |
| Inflammation, Dental Plaque | Altered Intercellular Communication | This shows the influence of inflammation on stress/strain calculations which are closely related to plaque assessment. | 27847118 |
| Inflammation | Altered Intercellular Communication | BACKGROUND Serum albumin (ALB) may be low during acute inflammation, but it is also affected by nutritional status. | 27848931 |
| Inflammation | Altered Intercellular Communication | These results suggest that, in addition to inflammation, assessment of patient nutritional status could also aid in identifying CD activity. | 27848931 |
| Inflammation, Myeloid | Altered Intercellular Communication | Interplay of Toll-Like Receptor 9, Myeloid Cells, and Deubiquitinase A20 in Periodontal Inflammation. | 27849177 |
| Inflammation, Periodontitis | Altered Intercellular Communication | Clinically, A20 was modestly upregulated in human gingival tissue specimens from chronic periodontitis patients, further confirming the biological relevance of A20 in periodontal inflammation. | 27849177 |
| Inflammation, Periodontal Diseases | Altered Intercellular Communication | We conclude that TLR9 modulates periodontal disease progression at both the cellular and molecular level and identify A20 as a novel downstream signaling molecule in the course of periodontal inflammation. | 27849177 |
| Inflammation, Periodontitis, Chronic inflammatory disorder | Altered Intercellular Communication | Understanding the regulation of the TLR9 signaling pathway and the involvement of A20 as a limiting factor of inflammation will uncover alternative therapeutic targets to treat periodontitis and other chronic inflammatory diseases. | 27849177 |
| Inflammation, Diabetic Retinopathy | Altered Intercellular Communication | Myeloid-Related Protein-14/MRP-14/S100A9/Calgranulin B is Associated with Inflammation in Proliferative Diabetic Retinopathy. | 27849448 |
| Inflammation, PDR gene | Altered Intercellular Communication | Increased MRP-14 levels are associated with inflammation in PDR. | 27849448 |
| Nasopharyngeal carcinoma | Altered Intercellular Communication | A Novel Inflammation-Based Stage (I Stage) Predicts Overall Survival of Patients with Nasopharyngeal Carcinoma. | 27854304 |
| Inflammation, hepcidin | Altered Intercellular Communication | Hepcidin-25 serves as a key peptide in the regulation of iron homeostasis and inflammation. | 27855289 |
| Inflammation, Anemia, Sickle Cell, Hemolysis (biological function), Albuminuria | Altered Intercellular Communication | Albuminuria, serum antioxidant enzyme levels and markers of hemolysis and inflammation in steady state children with sickle cell anemia. | 27855647 |
| Inflammation, Albuminuria, Hemolysis (biological function) | Altered Intercellular Communication | Albuminuria is associated with decreased antioxidant capacity and increased levels of markers of hemolysis and inflammation. | 27855647 |
| Cardiac Arrest, Inflammation, Hemolysis (biological function), Kidney Diseases | Altered Intercellular Communication | Therefore, strategies targeting the reduction of sickling and subsequent hemolysis, oxidative stress and inflammation could help preventing or at least delaying the progression of kidney disease in SCA children. | 27855647 |
| Refractory anemias, Sarcoidosis, Pulmonary, Dysbiosis | Altered Intercellular Communication | Distal airway dysbiosis is present in untreated early RA and similar to that detected in sarcoidosis lung inflammation. | 27855721 |
| Inflammation, Dehydration | Altered Intercellular Communication | Studies are necessary to understand whether correcting underlying dehydration and inflammation further improves patients' outcomes. | 27856199 |
| Cutaneous Radiation Injury, TRAF3IP2 gene, Inflammation, Granulation finding | Altered Intercellular Communication | aCT1 is a Cx43 mimetic peptide that in preclinical studies accelerated wound closure, decreased inflammation and granulation tissue area, and normalized mechanical properties after cutaneous injury. | 27856288 |
| Inflammation, Obesity | Altered Intercellular Communication | The prevalence of obesity or equivalent was 65%, of which 30% did not have inflammation. | 27856456 |
| Inflammation, Chronic heart failure | Altered Intercellular Communication | Myocardial 123I-mIBG scintigraphy in relation to markers of inflammation and long-term clinical outcome in patients with stable chronic heart failure. | 27858345 |
| Chronic heart failure, Myocarditis, Congestive heart failure | Altered Intercellular Communication | Chronic heart failure (CHF) results in both increased cardiac sympathetic activity and myocardial inflammation. | 27858345 |
| Inflammation, Congestive heart failure | Altered Intercellular Communication | Inflammation and cardiac sympathetic activity seem not to be related in stable CHF patients. | 27858345 |
| Papillary, Inflammation, palladium | Altered Intercellular Communication | Dental examination included: 1) dental findings (decayed, missing, and/or filled adult teeth [DMF-T] index); 2) gingival inflammation (papillary bleeding index [PBI]); and 3) periodontal status (probing depth [PD], attachment loss [AL]). | 27858553 |
| Tumor necrosis, Immune-mediated | Altered Intercellular Communication | Repeat imaging demonstrated increased size of the lesion, reflecting immune-mediated inflammation and tumor necrosis. | 27858578 |
| Inflammation | Altered Intercellular Communication | The patient underwent partial hepatectomy for the cystic mass of the liver and a final diagnosis of chronic inflammation of an intrahepatically located accessory GB was made. | 27858902 |
| Airway structure, Allergy - Charge Type Reason | Altered Intercellular Communication | Double-blind placebo-controlled challenge showed that peanut oral immunotherapy was effective for severe allergy without negative effects on airway inflammation. | 27859599 |
| Airway structure, Hypersensitivity | Altered Intercellular Communication | Peanut OIT was efficacious in severe allergies without negative effects on airway inflammation, but unpredictable long-term reactions might occur. | 27859599 |
| Inflammation | Altered Intercellular Communication | We tested the hypothesis that birthweight was inversely associated with serum high sensitivity C reactive protein assay (hsCRP), a measure of both innate immunity and systemic inflammation. | 27859847 |
| Inflammation, Cardiovascular Diseases, Osage language, Hypoxia, Endothelial dysfunction | Altered Intercellular Communication | Intermittent hypoxia, endothelial dysfunction and adipose tissue-mediated inflammation have all been linked to cardiovascular disease in OSA. | 27860068 |
| Inflammation, Traumatic injury | Altered Intercellular Communication | For various reasons, including trauma and inflammation, it may become elongated. | 27860211 |
| Inflammation, Neoplasms | Altered Intercellular Communication | Chronic inflammation plays an important role in tumor progression. | 27860387 |
| Chronic lymphocytic inflammation, Pontine structure, Clippers, Epstein-Barr Virus Infections | Altered Intercellular Communication | Chronic lymphocytic inflammation with pontine perivascular enhancement responsive to steroids (CLIPPERS) with intracranial Epstein-Barr virus infection: A Case Report. | 27861371 |
| Chronic lymphocytic inflammation, Pontine structure, Clippers, Inflammatory disorder | Altered Intercellular Communication | Chronic lymphocytic inflammation with pontine perivascular enhancement responsive to steroids (CLIPPERS) is an inflammatory disorder in the central nervous system (CNS) with distinct clinical, radiological, and pathological features. | 27861371 |
| Inflammation | Altered Intercellular Communication | In the same group, increased non-classical monocyte subset up-regulated TLR4-NFkB-iNOS and p38MAPK pathway, stimulated TNFa/nitrite production and elicited systemic inflammation. | 27861595 |
| Periodontal Diseases, Inflammation, RTEL1 gene | Altered Intercellular Communication | Whether periodontal disease is a direct or indirect cause of NHL, or is a marker of underlying systemic inflammation and/or immune dysregulation, warrants further investigation. | 27861844 |
| Primary malignant neoplasm, Periodontal Diseases, Chronic disease | Altered Intercellular Communication | Periodontal disease is a chronic inflammatory condition that has been associated with chronic diseases, including cancer. | 27861844 |
| Inflammation, Chronic disease, MS gene | Altered Intercellular Communication | After CIS, a chronic disease course with ongoing inflammation and relapses might occur, resulting in a diagnosis of multiple sclerosis (MS). | 27862730 |
| Inflammation, Tubulitis Assessment | Altered Intercellular Communication | At 1 year, subclinical inflammation occurred more frequently in group A than group B (inflammation score [i] >0: 21.4% vs. 8.8%, p = 0.047; tubulitis score [t] >0: 19.6% vs. 8.7%, p = 0.076; i + t: 1.14 +- 1.21 vs. 0.72 +- 1.01, p = 0.038). | 27862923 |
| Unknown (origin) (qualifier value), Pericarditis, CTCAE, Inflammation | Altered Intercellular Communication | Pericarditis is an inflammation of the pericardium and 90% of isolated cases of acute pericarditis are idiopathic or viral. | 27863892 |
| Psoriatic Juvenile Idiopathic Arthritis, Inflammation, Psoriasis, Liver diseases | Altered Intercellular Communication | FABP4 may be a marker of psoriasis, and FABP3 may be associated with inflammation or liver disorders in psoriatic patients. | 27864793 |
| Inflammation, Pseudoaneurysm, Bacterial Endocarditis | Altered Intercellular Communication | At autopsy, destruction of the noncoronary cusp of the aortic valve by bacterial endocarditis was found with extension of the inflammation into a pseudoaneurysm of the SoV with surrounding abscess formation involving the atrioventricular node. | 27864952 |
| Sepsis, Inflammation, Hypoxia | Altered Intercellular Communication | Adrenomedullin is released by different tissues in hypoxia, oxidative stress, and inflammation and is found in general and medical patients and, recently, in sepsis patients in emergency departments. | 27865148 |
| Refractory anemias, Inflammation, Erosion lesion | Altered Intercellular Communication | These cytokines, as upstream inhibitors of IL-34, may thus contribute to antagonize inflammation and bone erosions in RA. | 27865758 |
| Inflammation, Osseous metaplasia, Fibrosis Assessment, Metaplasia, Calcified (qualifier), Cartilaginous metaplasia | Altered Intercellular Communication | AVS cusps showed structural remodeling as severe fibrosis (100%), calcific nodules (100%), neoangiogenesis (81%), inflammation (71%), bone metaplasia with or without hematopoiesis (6% and 53%, respectively), adipose metaplasia (16%), and cartilaginous metaplasia (7%). | 27866029 |
| Inflammation, Atherosclerosis | Altered Intercellular Communication | Improvements in inflammation and insulin resistance seem to be mechanisms involved in the mitigation of atherosclerosis by empagliflozin. | 27866224 |
| Inflammation | Altered Intercellular Communication | Accumulation of tissue macrophages is a significant characteristic of disease-associated chronic inflammation, and facilitates the progression of disease pathology. | 27866511 |
| Dysplasia, Lichenoid inflammation | Altered Intercellular Communication | Disease-free status was less likely for erythroleukoplakia (P=0.022), 'high-grade' dysplasia (P<0.0001), and with lichenoid inflammation (P=0.028). | 27866683 |
| Inflammation, Tubulointerstitial nephritis and uveitis | Altered Intercellular Communication | In TINU syndrome, inflammation affects the renal tubules, interstitial tissue, and uveal tract. | 27867184 |
| Inflammation, Fibrosis Assessment, Hepatomegaly, FAM126A gene | Altered Intercellular Communication | After 30 months of follow-up, the liver pathology of the mice fell into four groups: G1, chronic inflammation solely; G2, chronic inflammation and fibrosis; G3, inflammation, fibrosis, and hepatomegaly accompanied by rectal prolapse (4-12%); and G4, hepatomegaly and spontaneous HCC (12-15%). | 27868197 |
| Inflammation, Leukopenia | Altered Intercellular Communication | The lack of massive tissue inflammation, probably due to the neutropenia in our patient, has not been described by other authors. | 27869489 |
| Inflammation, Anemia | Altered Intercellular Communication | Further studies in patients with more severe anaemia and patients with inflammation are warranted. | 27870058 |
| Inflammation, Malnutrition, Overhydration, HD Term Type, Cardiac dysfunction, Muscle Tissue | Altered Intercellular Communication | NT-proBNP may be an independent biomarker for malnutrition in HD patients, especially in patients with muscles loss, regardless of chronic inflammation, cardiac dysfunction, or overhydration. | 27870908 |
| Inflammation, Edema | Altered Intercellular Communication | The muscles showed edema and scattered inflammation at the very beginning, and then gradually formed mature bone tissue. | 27871317 |
| Inflammation | Altered Intercellular Communication | Our results suggest that age and virus mediated inflammation are correlated with disease phenotypes while additional factors such as host or HTLV-1 genetics and gender may influence disease susceptibility. | 27871430 |
| Gingivitis | Altered Intercellular Communication | During a review of her medical history, the patient reported using cannabis frequently during a 3-year period, which coincided with the occurrence of gingival inflammation. | 27871617 |
| Inflammation, Data types - Address | Altered Intercellular Communication | A large body of evidence suggests that inflammation is closely associated with AD pathogenesis and may be a promising target pathway for such interventions. | 27872486 |
| Inflammation, Data types - Address | Altered Intercellular Communication | However, little is known about the association between systemic inflammation and preclinical AD pathophysiology. | 27872486 |
| Nausea, Diarrhea, Inflammatory disease of mucous membrane, Fatigue | Altered Intercellular Communication | Frequent (any grade) treatment-related adverse events (AEs) included diarrhea (83%), rash/acne (83%), fatigue (79%), mucosal inflammation (59%), and nausea (59%). | 27872953 |
| Inflammation, Rectal Carcinoma | Altered Intercellular Communication | The current study examined the association between systemic inflammation and nCRT in patients with rectal cancer. | 27873100 |
| Aneurysm, Inflammation | Altered Intercellular Communication | In the light of recent reports of the association of wall enhancement with unstable aneurysms, we considered wall enhancement to be a marker of inflammation and remodeling of the aneurysm wall, resulting in chronic hemorrhagic suffusion in the subarachnoid spaces. | 27873743 |
| Communicable Diseases, Traumatic injury | Altered Intercellular Communication | Oral PG is often caused by constant low-grade infection, minor trauma, poor oral hygiene, and due to hormonal disturbances. | 27874157 |
| Acromegaly, Neoplasms | Altered Intercellular Communication | We present data from the PRIMARYS study on the impact of the SSA lanreotide, associated with tumour volume and hormonal improvements, on glucose and other metabolic parameters in acromegaly. | 27874199 |
| Short Bowel Syndrome, antimony, Chronic intestinal failure | Altered Intercellular Communication | An impaired hormonal "ileo-colonic brake" may contribute to rapid gastric emptying, gastric hypersecretion, high ostomy losses, and the need for parenteral support in end-jejunostomy short bowel syndrome (SBS) patients with intestinal failure (IF). | 27875281 |
| Inflammation, Chronic heart failure | Altered Intercellular Communication | Orosomucoid as prognosis factor associated with inflammation in acute or nutritional status in chronic heart failure. | 27875723 |
| Inflammation, Heart failure | Altered Intercellular Communication | Inflammation and nutritional state are involved in the pathogenesis of heart failure (HF). | 27875723 |
| Inflammation, Injury of musculoskeletal system, abdominal adhesions, Tissue Adhesions | Altered Intercellular Communication | The etiology for this phenomenon was thought to be abdominal adhesions caused by inflammation and viscero-somatic reflexes caused by adhesions or injury to visceral or musculoskeletal system structures. | 27876238 |
| Inflammation, trauma to the abdomen, Digestive Epilepsy, Tissue Adhesions, Epilepsy | Altered Intercellular Communication | If substantiated in further research, present study results will require further examination of the mechanisms of action for epilepsy, and suggest the need for re-examination of older formulations of abdominal epilepsy, including the place of abdominal injury, inflammation, and adhesions in epileptic pathology. | 27876238 |
| Kidney Failure, Chronic, Atherosclerosis | Altered Intercellular Communication | Activation of the CXCL16/CXCR6 Pathway by Inflammation Contributes to Atherosclerosis in Patients with End-stage Renal Disease. | 27877078 |
| Inflammation, Atherosclerosis | Altered Intercellular Communication | Background: Chronic inflammation plays a critical role in the progression of atherosclerosis (AS). | 27877078 |
| Kidney Failure, Chronic, Inflammation | Altered Intercellular Communication | Conclusions: Inflammation contributed to foam cell formation in the radial arteries of ESRD patients via activation of the CXCL16/CXCR6 pathway, which may be regulated by P2X7R. | 27877078 |
| Inflammation | Altered Intercellular Communication | These results are consistent with the hypothesis that diet-associated inflammation determines LTL. | 27878970 |
| Respiratory Distress Syndrome, Adult, Inflammation | Altered Intercellular Communication | Expression of miRNA is increased in blood leukocytes of patients with ARDS at day 0 and day 3 and rises further by day 7, when systemic inflammation is subsiding. | 27879560 |
| Cellulitis | Altered Intercellular Communication | Recurrent Orbital Inflammation Mimicking Orbital Cellulitis Associated With Orbitopalpebral Venous Lymphatic Malformation. | 27879620 |
| Orbital Pseudotumor | Altered Intercellular Communication | Over 8 months of follow up, he had 2 acute episodes of severe orbital inflammation that warranted hospitalization and treatment with intravenous antibiotic, steroids and surgical debulking. | 27879620 |
| ARCN1 gene, Inflammation, Chronic Obstructive Airway Disease | Altered Intercellular Communication | Chronic obstructive pulmonary disease (COPD) is characterised by progressive and irreversible airflow limitation associated with chronic inflammation involving cytokines and metalloproteinases (MMPs). | 27880043 |
| Airway structure, Inflammation, Chest tightness | Altered Intercellular Communication | We propose that the chest tightness relieved with bronchodilator use was attributed to airway constriction resulting from inflammation with lymphocytes and macrophages and/or that the chest tightness was directly attributed to airway inflammation. | 27880056 |
| Inflammation | Altered Intercellular Communication | The underlying pathogenesis was postulated to be localised inflammation and pathological aberrant vessels formation. | 27881024 |
| Inflammation, SDSL gene | Altered Intercellular Communication | It was found to inhibit inflammation and promote vascular maturation at the neomembrane of CSDH. | 27881024 |
| Arterial Stiffness, Inflammation | Altered Intercellular Communication | Patients with peritoneal dialysis are in the persistent inflammation state and have elevated arterial stiffness. | 27881094 |
| Non-alcoholic Fatty Liver Disease, Somatotropin deficiency | Altered Intercellular Communication | Growth hormone deficiency (GHD) is associated with non-alcoholic fatty liver disease (NAFLD). | 27881164 |
| Prediabetes syndrome, diabetic | Altered Intercellular Communication | Assessment of Carotid Plaque Inflammation in Diabetic and Nondiabetic Patients-An Exploratory Ultrasmall Superparamagnetic Iron Oxide-Enhanced Magnetic Resonance Imaging Study. | 27881291 |
| Inflammation, Atheroma, atherosclerotic | Altered Intercellular Communication | Ultrasmall superparamagnetic iron oxide (USPIO)-enhanced magnetic resonance (MR) imaging enables the identification of inflammation within the atheroma, predominantly by USPIO uptake by macrophages present in atherosclerotic tissue. | 27881291 |
| Inflammation, diabetic | Altered Intercellular Communication | Diabetic patients, however, may have dysfunctional macrophage activity, which may affect utilization of USPIO in identifying plaque inflammation in this patient cohort. | 27881291 |
| Inflammation, Malnutrition | Altered Intercellular Communication | Assessment of Regression Models for Adjustment of Iron Status Biomarkers for Inflammation in Children with Moderate Acute Malnutrition in Burkina Faso. | 27881597 |
| Inflammation | Altered Intercellular Communication | Regression analysis is an alternative to adjust SF and may be preferable in research settings, because it can take morbidity and severity of inflammation into account. | 27881597 |
| Inflammation | Altered Intercellular Communication | The levels of systemic inflammation markers increased with the involvement of larger and/or more joints. | 27882446 |
| Inflammation | Altered Intercellular Communication | Combined treatment might be particularly relevant in those conditions where increased inflammasome activation may lead to GR degradation and steroid-unresponsive inflammation. | 27883019 |
| Inflammation, Atherosclerosis | Altered Intercellular Communication | Inflammation has a key role in the process of atherosclerosis. | 27883201 |
| Inflammation, Foot Ulcer, diabetic | Altered Intercellular Communication | Negative pressure wound therapy inhibits inflammation and upregulates activating transcription factor-3 and downregulates nuclear factor-kB in diabetic patients with foot ulcerations. | 27883358 |
| Inflammation, diabetic | Altered Intercellular Communication | After 7 days of treatment, NPWT could obviously promote diabetic wound healing because of the mild inflammation and the dense cell-deposited matrix. | 27883358 |
| Uremia, Inflammation, Bacterial Infections, Vascular calcification | Altered Intercellular Communication | The ensuing impairment of neutrophil function can contribute to the chronic inflammation state of uremic patients, and the increased risk of bacterial infections or vascular calcifications. | 27884120 |
| Infectious gastroenteritis, Gastroenteritis | Altered Intercellular Communication | increased adult burden of infectious gastroenteritis and genetic diversity of circulating rotaviruses; adults infected with rotavirus developed more severe gastroenteritis symptoms (p<0.01) accompanied with mild intestinal and blood inflammations. | 27884652 |
| Inflammation, Crohn Disease | Altered Intercellular Communication | Rectal inflammation was present in 29 patients with Crohn's disease (29.2%) and in 2 without Crohn's (6.7%). | 27885389 |
| Inflammation, Crohn Disease | Altered Intercellular Communication | Our study demonstrates that while both groups can have similar MR imaging features, accompanying rectal inflammation was more commonly seen in Crohn's disease. | 27885389 |
| Inflammation, Neoplasms, Fibrosis Assessment, FAM126A gene, ABR gene | Altered Intercellular Communication | The presence of MDB in tumours was associated with the steatohepatitic variant of HCC, which also showed fatty change, ballooning of tumour cells, MDBs, inflammation and pericellular fibrosis (P<.001). | 27885796 |
| Inflammation | Altered Intercellular Communication | Inflammation plays an important role in development of coronary collateral circulation (CCC). | 27885839 |
| Inflammation, Stomach Carcinoma, Atrophic | Altered Intercellular Communication | Patients with cagA- and vacA-positive H. pylori have a higher risk of severe inflammation and atrophy and should therefore be monitored for the development of gastric cancer. | 27886029 |
| Inflammation, Impaired cognition, Atherosclerosis | Altered Intercellular Communication | Our findings suggest that systemic chronic inflammation, potentially associated with underlying atherosclerosis, is related to cognitive impairment and decline two decades later, in elderly individuals with pre-existing CVD. | 27886564 |
| Airway structure, Asthma | Altered Intercellular Communication | Fractional exhaled nitric oxide (FeNO) is considered an alternative marker of eosinophilic airway inflammation and is sometimes incorporated in the diagnosis of asthma. | 27886852 |
| Cancer-related fatigue | Altered Intercellular Communication | Corticotropin-releasing factor (CRF) is a neurohormone released from the paraventricular nucleus of the hypothalamus into the median eminence to elicit release of adrenocorticotrophin from the anterior pituitary. | 27887910 |
| Communicable Diseases, Inflammation | Altered Intercellular Communication | There was evidence of CBG cleavage in early infection both in patients with and without systemic inflammation and regardless of culture status. | 27887960 |
| Inflammation, Leukocytosis, Hepatitis, Cachexia | Altered Intercellular Communication | Skin carcinogenesis was associated with progressive, severe, systemic inflammation (leukocytosis, hepatitis, splenitis), significant mortality and cachexia. | 27888116 |
| Hepatic inflammation, muscle mass | Altered Intercellular Communication | Preservation of muscle mass and reduced hepatic inflammation were associated with down-regulation of the NF-kB canonical pathway and with reduced oxidative stress, respectively. | 27888116 |
| Inflammation, Fibromyalgia, Federated States of Micronesia | Altered Intercellular Communication | Chronic inflammation, which changes the neurotransmitter metabolism and kindles neuroendocrine system dysfunction in the central nervous system, might cause fibromyalgia (FM) formation. | 27888118 |
| Inflammation, cyclophosphamide/methotrexate/vincristine protocol, Chronic osteomyelitis | Altered Intercellular Communication | Thus, we investigated whether chronic osteomyelitis (COM), a disease characterized by chronic inflammation, increases FM risk. | 27888118 |
| Inflammation, Fibromyalgia, Federated States of Micronesia | Altered Intercellular Communication | Chronic inflammation, which changes the neurotransmitter metabolism and kindles neuroendocrine system dysfunction in the central nervous system, might cause fibromyalgia (FM) formation. | 27888118 |
| Parkinson Disease, Inflammation, palladium, Neurodegenerative Disorders | Altered Intercellular Communication | Inflammation is likely a key contributor to the pathogenesis of Parkinson's disease (PD), a progressively debilitating neurodegenerative disease that is accompanied by a pathological accumulation of the a-synuclein protein in a staged manner through the brain. | 27888296 |
| palladium, Inflammation | Altered Intercellular Communication | Toll-like receptor (TLR) signaling is a major pathway mediating inflammation and, in particular, TLR2 is increasingly being implicated in PD. | 27888296 |
| Inflammation, Chronic sinusitis, Craniosynostosis, Chronic infectious disease | Altered Intercellular Communication | Eosinophilic chronic rhinosinusitis (eCRS) has recently been recognized as a CRS subtype characterized by inflammation rather than chronic infection. | 27888519 |
| Inflammation, Axial spondyloarthritis | Altered Intercellular Communication | Prevalence and topographic distribution of spinal inflammation on MR imaging in patients recently diagnosed with axial spondyloarthritis. | 27889235 |
| HSPG2 wt Allele | Altered Intercellular Communication | Recombinant serotype 2 adeno-associated viral (rAAV2) vectors expressing either OB-R shRNA (rAAV2-shOB-R) or none (rAAV2-null) were injected into 4 or 16 week-old BALB/c NOD/LtJ (NOD) mice and resulted in a modest reduction in glandular inflammation in the SjS model. | 27889607 |
| Communicable Diseases, Inflammation, Impaired cognition, Breast Carcinoma | Altered Intercellular Communication | Although the pathophysiology of the condition is complex, alterations in systemic cytokines, signaling molecules activated in response to infection or injury that trigger inflammation, are a possible mechanism linked to cognitive dysfunction in breast cancer and other conditions. | 27890459 |
| Inflammation, Neoplasms, Glioblastoma Multiforme Pathway | Altered Intercellular Communication | Functional analysis performed on each group reveals sub-networks related to neoplasia for group 1, glioma with inflammation for group 2 and neurogenesis for group 3. | 27890679 |
| Inflammation, Primary malignant neoplasm | Altered Intercellular Communication | Purpose The sequelae of cancer treatment may increase systemic inflammation and create a phenotype at increased risk of functional decline and comorbidities, leading to premature mortality. | 27893337 |
| Pain Distress Question, Primary malignant neoplasm, Inflammation, GDC Comorbidity Terminology | Altered Intercellular Communication | Survivors treated with surgery, radiation, and chemotherapy accumulated a significantly greater burden of comorbid conditions and suffered greater pain associated with inflammation over time after cancer treatment than did the control group. | 27893337 |
| Sepsis, Inflammation | Altered Intercellular Communication | The downregulation of blood monocyte HLA-DR expression also occurs in tissue infiltrative cells in a context of acute clinical inflammation, especially sepsis. | 27893741 |
| Inflammation, Telangiectasis, Pulmonary Fibrosis | Altered Intercellular Communication | Dysbiosis was more severe in patients with skin telangiectasias (p = 0.020), pitting scars (p = 0.023), pulmonary fibrosis (p = 0.009), and elevated serum markers of inflammation (p < 0.001). | 27894337 |
| Inflammation, Lupus Erythematosus | Altered Intercellular Communication | Association between the cytotoxic T-lymphocyte antigen-4 mutations and the susceptibility to systemic lupus erythematosus; Contribution markers of inflammation and oxidative stress. | 27894401 |
| Inflammation, Intraepithelial Neoplasia | Altered Intercellular Communication | Fifty-four lesions (65%) were histologically diagnosed as SESCCs and the others as low-grade intraepithelial neoplasia or inflammation. | 27895406 |
| Communicable Diseases, Acute inflammation | Altered Intercellular Communication | It characteristically presents with acute inflammation, resulting in demyelination, often following an infectious disease. | 27896893 |
| Inflammation, Sleep Apnea, Obstructive, Carotid Intima-Media Thickness, Metabolic Syndrome X | Altered Intercellular Communication | Impact of inflammation and oxidative stress on carotid intima-media thickness in obstructive sleep apnea patients without metabolic syndrome. | 27896929 |
| Inflammation, Osage language | Altered Intercellular Communication | This study tested the hypothesis that inflammation and oxidative stress determined carotid IMT in patients with OSA. | 27896929 |
| Inflammation, Chronic Kidney Diseases | Altered Intercellular Communication | Toll-like receptor 4 signalling mediates inflammation in skeletal muscle of patients with chronic kidney disease. | 27897392 |
| Uremia, Inflammation, Skeletal muscle structure, Cachexia | Altered Intercellular Communication | Inflammation in skeletal muscle is implicated in the pathogenesis of insulin resistance and cachexia but why uremia up-regulates pro-inflammatory cytokines is unknown. | 27897392 |
| Chronic Kidney Diseases, Myositis | Altered Intercellular Communication | CKD promotes muscle inflammation through an up-regulation of TLR4, which may activate downward inflammatory signals such as TNF-a and NFkB-regulated genes. | 27897392 |
| Chronic Kidney Diseases, Myositis | Altered Intercellular Communication | CKD promotes muscle inflammation through an up-regulation of TLR4, which may activate downward inflammatory signals such as TNF-a and NFkB-regulated genes. | 27897392 |
| Inflammation, Carcinoma of lung | Altered Intercellular Communication | Cancer anorexia: hypothalamic activity and its association with inflammation and appetite-regulating peptides in lung cancer. | 27897393 |
| Primary malignant neoplasm, Anorexia | Altered Intercellular Communication | Energy homeostasis is mediated by the hypothalamus, whose inflammation-induced functional derangements contribute to the onset of anorexia in cancer. | 27897393 |
| Inflammation | Altered Intercellular Communication | Low SMD appears to correlate with fat accumulation in muscle and is associated with inflammation. | 27897411 |
| Inflammation | Altered Intercellular Communication | Chronic inflammation, changes in body composition, and declining physical function are hallmarks of the ageing process. | 27897412 |
| Inflammation | Altered Intercellular Communication | Interleukin-4 (IL-4) together with interleukin-13 (IL-13) play an important role in inflammation and wound repair, and are known to be upregulated in human skeletal muscle after strenuous physical exercise. | 27897439 |
| Inflammation | Altered Intercellular Communication | Quercetin (Qe) plays an important role in inflammation, antibacterial, anticancer, and aging. | 27898345 |
| Inflammation, Pain Distress Question | Altered Intercellular Communication | Our findings showed a relationship between inflammation and LBP by establishing that low IL-6 plasma levels preceded outcome (LBP recovery), supporting the concept that proinflammatory cytokines promote pain. | 27898478 |
| Inflammation, Idiopathic osteoarthritis | Altered Intercellular Communication | Chronic synovial inflammation causes primary osteoarthritis, but it is unknown whether chronic systemic inflammation does, too. | 27898694 |
| Inflammation, Idiopathic osteoarthritis, Liver Cirrhosis | Altered Intercellular Communication | Patients with cirrhosis have chronic systemic inflammation and therefore we examined the association between cirrhosis and primary osteoarthritis of the hip and knee. | 27898694 |
| Inflammation, Idiopathic osteoarthritis, Liver Cirrhosis | Altered Intercellular Communication | Cirrhosis, and thus chronic systemic inflammation, is not a risk factor for primary osteoarthritis. | 27898694 |
| Airway structure, Communicable Diseases, ARCN1 gene | Altered Intercellular Communication | Relationships between Mucosal Antibodies, Non-Typeable Haemophilus influenzae (NTHi) Infection and Airway Inflammation in COPD. | 27898728 |
| ARCN1 gene, Airway structure | Altered Intercellular Communication | Non-typeable Haemophilus influenzae (NTHi) is a key pathogen in COPD, being associated with airway inflammation and risk of exacerbation. | 27898728 |
| ARCN1 gene, Communicable Diseases, Inflammation | Altered Intercellular Communication | The aim of our study (NCT01701869) was to quantify the amount and specificity of antibodies against NTHi in the lungs and the associated risk of infection and inflammation in health and COPD. | 27898728 |
| ARCN1 gene, Inflammation, Exacerbation | Altered Intercellular Communication | NTHi was detected in the lungs of 7 of the COPD patients (NTHi+ve-29%) and these patients had a higher median number of previous exacerbations than NTHi-ve patients as well as evidence of increased systemic inflammation. | 27898728 |
| Airway structure, ARCN1 gene | Altered Intercellular Communication | This decrease in total and NTHI-specific IgG1 was associated with greater systemic and airway inflammation and a history of more frequent exacerbations and may explain the susceptibility of some COPD patients to the impacts of NTHi. | 27898728 |
| Inflammation, Knee pain | Altered Intercellular Communication | Dietary fiber may reduce knee pain, in part by lowering body weight and reducing inflammation. | 27899003 |
| Inflammation | Altered Intercellular Communication | Gene ontology analysis showed higher prevalence of VFA-associated genes than that of SFA-associated genes, among the genes associated with inflammation, oxidative stress, immune response, lipid metabolism, and glucose metabolism. | 27899146 |
| Inflammation, Edema | Altered Intercellular Communication | He was treated with topical ganciclovir and ketorolac, and the inflammation and oedema resolved. | 27899387 |
| Inflammation, Observation Method - Coagulation | Altered Intercellular Communication | Secondary outcome parameters included biomarkers for inflammation, coagulation and endothelial function and lipid profiles. | 27899529 |
| Inflammation, Primary malignant neoplasm | Altered Intercellular Communication | Cancer causes systemic inflammation which interrupts iron metabolism leading to a functional iron deficiency (FID). | 27900547 |
| Inflammation, Hypochromatism | Altered Intercellular Communication | We assessed the numbers of patients with abnormal values for haemoglobin, % hypochromic red cells (>5% indicates iron-restricted erythropoiesis) and CRP (>10 indicates systemic inflammation). | 27900547 |
| Ischemia, Inflammation | Altered Intercellular Communication | Diabetic hyperglycemia damages peripheral nerves by triggering ischemia, oxidative stress, and inflammation. | 27901334 |
| Inflammation | Altered Intercellular Communication | Cardiac Troponin Release is Associated with Biomarkers of Inflammation and Ventricular Dilatation During Critical Illness. | 27902530 |
| Troponin T, Cardiac Muscle, Inflammation, Ventricular dilatation (disorder) | Altered Intercellular Communication | We hypothesized that there was an association between cardiac troponin T (cTnT) and biomarkers of systemic inflammation and ventricular dilatation. | 27902530 |
| Inflammation, Superinfection | Altered Intercellular Communication | Skin overlying the typical subcutaneous inflammation may appear normal, and bacterial superinfections of the skin sometimes mask the underlying LP. | 27902603 |
| Hyperglycemia | Altered Intercellular Communication | A state of obesity-related inflammation plus hyperglycemia may trigger increased alloreactivity and should call for adequate immunosuppression. | 27903445 |
| APP gene, Inflammation, Aortic Aneurysm, Abdominal, Rupture | Altered Intercellular Communication | Abdominal aortic aneurysm (AAA) wall inflammation and mechanical structural stress may influence AAA expansion and lead to rupture. | 27903534 |
| Inflammation, Blood Clot | Altered Intercellular Communication | Compared with other factors, structural stress was the best predictor of inflammation (receiver-operating characteristic curve area under the curve =0.59), with higher accuracy seen in regions with high thrombus burden (area under the curve =0.80). | 27903534 |
| Inflammation, Blood Clot | Altered Intercellular Communication | Increased aortic wall inflammation, demonstrated by 18F-FDG positron emission tomography, was observed in AAA regions with thick intraluminal thrombus subjected to high mechanical stress, suggesting a potential mechanistic link underlying aneurysm inflammation. | 27903534 |
| Inflammation, Electrocardiogram: myocardial infarction (finding), Atrial Fibrillation by ECG Finding | Altered Intercellular Communication | The association of plasma oxidative status and inflammation with the development of atrial fibrillation in patients presenting with ST elevation myocardial infarction. | 27905214 |
| Inflammation | Altered Intercellular Communication | Oxidative stress and inflammation may cause structural and electrical remodeling in the atria making these critical processes in the pathology of AF. | 27905214 |
| Inflammation, Atrial Fibrillation | Altered Intercellular Communication | The main finding of this study is that oxidative stress and inflammation parameters were associated with the development of AF in patients presenting with STEMI. | 27905214 |
| Cartilage destruction, Inflammation | Altered Intercellular Communication | IFP may trigger both cartilage destruction and inflammation of the synovium, but not through leptin or adiponectin. | 27908299 |
| Vascular Diseases, Inflammation, Impaired cognition, Myocardial dysfunction, Data types - Address | Altered Intercellular Communication | Whereas cognitive impairment has been linked to HF through perfusion defects, angiopathy, and inflammation, whether patients with AD present with myocardial dysfunction, and if the 2 conditions bear a common pathogenesis as neglected siblings are unknown. | 27908343 |
| FGFR1OP gene | Altered Intercellular Communication | We hypothesized that FOP patients develop characteristic deficiencies in inflammation-related trace elements and display a chronically increased inflammatory cytokine level, collectively aggravating disease course and flare-up risk. | 27908413 |
| Inflammation | Altered Intercellular Communication | Chronic systematic inflammation has been suggested to be associated with the occurrence and development of cardiovascular events. | 27908556 |
| Inflammation, Diabetes Mellitus, Non-Insulin-Dependent | Altered Intercellular Communication | Low-grade systematic inflammation persists in type 2 diabetes mellitus (T2DM) patients. | 27908556 |
| Inflammation, Cerebral Hemorrhage | Altered Intercellular Communication | NLR >2.58 might be useful in predicting the threshold value of cerebral hemorrhage risk in newly diagnosed T2DM patients (area under the curve: .72, 95% CI: .659-.780, P < .001) CONCLUSION: As an indicator of the degree of systematic inflammation, NLR is an independent risk factor of cerebral hemorrhage in T2DM patients. | 27908556 |
| APP gene, Inflammation, Aortic Aneurysm, Abdominal, Atherosclerotic lesion | Altered Intercellular Communication | High-mobility group box 1 (HMGB-1) is a key substance mediating inflammation and development of atherosclerotic lesions (ALs), including abdominal aortic aneurysms (AAA). | 27908811 |
| Inflammation, Specimen Type - Fistula, Digestive System Fistula | Altered Intercellular Communication | Effect of Oral o3-Polyunsaturated Fatty Acids as a Complement Management to Control Fistula Output and Inflammation in Patients With Digestive Fistula. | 27909869 |
| Digestive System Fistula, Fibrosis Assessment, Inflammation | Altered Intercellular Communication | The presence of digestive fistula involves chronic inflammation and fibrosis. | 27909869 |
| Inflammation, Aortic Aneurysm, Abdominal, Leukocytes, APP gene, Muscle, Smooth, Vascular | Altered Intercellular Communication | Inflammation with leukocytic infiltration, degradation of extracellular matrix (ECM), and depletion of vascular smooth muscle cells (VSMC) are pathological hallmarks of abdominal aortic aneurysm (AAA). | 27910812 |
| Inflammation, Depression, CTCAE, Bipolar Disorder | Altered Intercellular Communication | Depression with inflammation: longitudinal analysis of a proposed depressive subtype in community dwelling older adults. | 27911015 |
| Inflammation, Depression, CTCAE | Altered Intercellular Communication | It has been proposed that inflammation may be causally related to depression. | 27911015 |
| Inflammation, Depression, CTCAE | Altered Intercellular Communication | Participants with depression and inflammation (C Reactive Protein > 3 mg/l) were compared to those with depression alone. | 27911015 |
| Inflammation, Depression, CTCAE | Altered Intercellular Communication | In a longitudinal analysis, depression with associated inflammation was more likely to persist over time. | 27911015 |
| Inflammation, Depression, CTCAE | Altered Intercellular Communication | Inflammation either partially or completely mediated the association between medical co-morbidity, body mass index and depression at follow-up. | 27911015 |
| Inflammation, Depression, CTCAE | Altered Intercellular Communication | Depression with inflammation was associated with more amotivation, less sadness, greater medical co-morbidity and higher body mass index. | 27911015 |
| Immunoglobulin A deficiency (disorder) | Altered Intercellular Communication | Secretory IgA Deficiency in Individual Small Airways Is Associated with Persistent Inflammation and Remodeling. | 27911098 |
| ARCN1 gene, Inflammation, Chronic Obstructive Airway Disease | Altered Intercellular Communication | We examined the relationship between secretory IgA (SIgA) on the mucosal surface of small airways and parameters of inflammation and airway wall remodeling in chronic obstructive pulmonary disease (COPD). | 27911098 |
| ARCN1 gene, Immunoglobulin A deficiency (disorder), Inflammation | Altered Intercellular Communication | Our findings support the concept that localized, acquired SIgA deficiency in individual small airways of patients with COPD allows colonizing bacteria to cross the epithelial barrier and drive persistent inflammation and airway wall remodeling, even after smoking cessation. | 27911098 |
| Alzheimers Disease | Altered Intercellular Communication | These findings suggest that nitrosylation of VAChT and VGLUT1 may be associated with dysfunctional acetylcholinergic and glutamatergic neurotransmission in Alzheimer's disease. | 27911305 |
| Inflammation, Carcinogenesis, Liver and Intrahepatic Biliary Tract Carcinoma | Altered Intercellular Communication | Systemic inflammation is known to promote carcinogenesis in biliary tract cancer (BTC). | 27911876 |
| Inflammation | Altered Intercellular Communication | Neutrophil-to-lymphocyte ratio (NLR) and platelet-to-lymphocyte ratio (PLR) are indicative of systemic inflammation. | 27911876 |
| Inflammation, Neoplasms | Altered Intercellular Communication | Higher systemic inflammation status also had relation with a primary tumor site (p = 0.003) and higher levels of CEA (p = 0.038). | 27911876 |
| Inflammation | Altered Intercellular Communication | Systemic inflammation represented by NLR and PLR, predicts the OS of patients with advanced BTC who are receiving palliative chemotherapy. | 27911876 |
| Inflammation | Altered Intercellular Communication | Acute phase Hp level might reflect the severity of oxidative stress during inflammation process. | 27913007 |
| Inflammation, Fatigue | Altered Intercellular Communication | Fatigue has been linked to chronic inflammation, and diets high in antioxidant nutrients have been associated with lesser prevalence and severity of fatigue. | 27913933 |
| Degenerative polyarthritis | Altered Intercellular Communication | Inflammation of synovial membrane and degeneration of articular cartilage in osteoarthritis (OA) lead to major changes in joint space width (JSW) and biochemical components such as collagen-II telopeptide (CTX-II) and matrix metallo protineases (MMP-3, 8, and 13). | 27913970 |
| HD Term Type, Inflammation, Diabetes Mellitus | Altered Intercellular Communication | Plasma sRAGE and S100A12 may be weak surrogate markers for predicting all-cause mortality in patients undergoing HD, although S100A12 was partly related to diabetes and inflammation. | 27914132 |
| Inflammation, Meningitis | Altered Intercellular Communication | Mediators and Biomarkers of Inflammation in Meningitis: Cytokine and Peptidome Profiling of Cerebrospinal Fluid. | 27914455 |
| ARCN1 gene, Inflammation | Altered Intercellular Communication | The purpose of this analysis was to determine if patients with COPD have distinctive symptom profiles and to examine the association of symptom profiles with systemic biomarkers of inflammation. | 27914470 |
| Inflammation, Vasculitis, CTCAE | Altered Intercellular Communication | During vasculitis, activation of the kinin system induces inflammation, whereby the kinin B1-receptor is expressed and activated after ligand binding. | 27914700 |
| Inflammation, Vasculitis, CTCAE | Altered Intercellular Communication | Here we determined whether leukocyte-derived microvesicles bear B1-kinin receptors during vasculitis, and if microvesicles transfer functional B1-receptors to recipient cells, thus promoting inflammation. | 27914700 |
| Inflammation | Altered Intercellular Communication | Thus, we found a novel mechanism by which microvesicles transfer functional receptors and promote kinin-associated inflammation. | 27914700 |
| Inflammation | Altered Intercellular Communication | Patients presented inflammation syndrome and high levels of CXCL12, soluble stem cell factor and granulocyte colony-stimulating factor, whereas granulocyte macrophage colony-stimulating factor was low. | 27914820 |
| Inflammation, Uveitis | Altered Intercellular Communication | For patients with uveitis, disease activity (active vs. inactive) and grade of inflammation were recorded according to Standardization of Uveitis Nomenclature criteria. | 27914832 |
| Inflammation, Infection | Altered Intercellular Communication | Soluble urokinase-type plasminogen activator receptor (suPAR) is a glycoprotein secreted during inflammation and infections. | 27914940 |
| Inflammation, Neoplasms | Altered Intercellular Communication | High levels of inflammation in the tumour centre, but not the periphery were associated with better patient survival (p = 0.001), similar to high counts of intratumoural FoxP3+, CD3+, CD8+ TILs (p = 0.001; p = 0.027; p = 0.038) and a combination of CD3+/CD8+/FoxP3+ TILs, the latter displaying three different prognostic groups (triple high/mixed/triple low; p=0.003). | 27916317 |
| Inflammation, Neoplasms | Altered Intercellular Communication | In summary, both high grade total inflammation and high TIL counts in the tumour centre, but not the tumour periphery, show a beneficial prognostic impact on EAC. | 27916317 |
| Inflammation, Wounds and Injuries | Altered Intercellular Communication | Inflammation and activation of the innate immune system are often associated with traumatic injury and may involve alterations in toll-like receptor (TLR)-mediated responses. | 27916353 |
| Inflammation, Carcinoma of lung, HIV Infections | Altered Intercellular Communication | In our large HIV cohort in the antiretroviral therapy era, we found evidence that dysfunctional immune activation and chronic inflammation contribute to the development of lung cancer in the setting of HIV infection. | 27916584 |
| Inflammation | Altered Intercellular Communication | Acetylcholine (ACh) contributes to the modulation of central and peripheral inflammation. | 27916909 |
| Inflammation, Brain Injuries, COL4A2 wt Allele, Cerebral Hemorrhage | Altered Intercellular Communication | Inflammation plays a role in secondary brain injury after intracerebral hemorrhage (ICH). | 27917647 |
| Inflammatory abnormality of the eye | Altered Intercellular Communication | To report the epidemiology and classification of ocular inflammation at a tertiary eye care center in Singapore. | 27918224 |
| Inflammatory abnormality of the eye | Altered Intercellular Communication | The pattern of ocular inflammation in Singapore has similarities with both Western and Asian populations. | 27918224 |
| Inflammation, Tissue Factor | Altered Intercellular Communication | The prevalence of trachomatous inflammation - follicular (TF) in children aged 1-9 years was between 0.03% and 8% across the LGAs, with only one LGA (Igabi) having a TF prevalence >=5%. | 27918227 |
| Communicable Diseases, Inflammation | Altered Intercellular Communication | Thirty-five age-matched subjects without any infectious diseases or inflammation were selected as controls. | 27918431 |
| Renal Insufficiency, Inflammation, Abnormal renal function | Altered Intercellular Communication | Renal dysfunction in HFrEF was associated with both NLR and NGAL levels, but systemic inflammation reflected by NLR seemed to be a more important determinant of progression of kidney dysfunction. | 27918494 |
| Pancreatitis, Acute, Inflammation, Metabolic Diseases | Altered Intercellular Communication | Low-grade inflammation persists in patients with acute pancreatitis (AP) after hospital discharge, and is linked to metabolic disorders. | 27918953 |
| Inflammation | Altered Intercellular Communication | It may, however, induce complement activation and downstream inflammation due to bio-incompatibility. | 27919366 |
| Refractory anemias, Inflammation, Microabscess, Communicable Diseases | Altered Intercellular Communication | Except for microabscess found in one RA patient, all pathological sections showed mild chronic inflammation but no infection. | 27919672 |
| Inflammation, Fibrosis Assessment, Heart failure, Atherosclerosis | Altered Intercellular Communication | Heart failure and atherosclerosis share the underlying mechanisms of chronic inflammation followed by fibrosis. | 27920122 |
| Inflammation, Atherosclerosis | Altered Intercellular Communication | A highly conserved microRNA (miR), miR-33, is considered as a potential therapeutic target for atherosclerosis because it regulates lipid metabolism and inflammation. | 27920122 |
| Inflammation, "Extra-osseous Ewings sarcoma | Altered Intercellular Communication | We hypothesized that one function of eosinophils in EoE might be to regulate the T cell-driven inflammation in the oesophagus. | 27921303 |
| Cirrhotic | Altered Intercellular Communication | We conclude that gut-brain axis alterations may be associated with the type of neurobehavioral decline or inflamm-aging in elderly cirrhotic subjects. | 27922089 |
| Anomia, Inflammation | Altered Intercellular Communication | Cirrhotics were impaired on non-amnestic and selected amnestic tests, HRQOL and systemic inflammation compared to non-cirrhotics. | 27922089 |
| Inflammation, Fibrosis Assessment, Lung diseases | Altered Intercellular Communication | Inflammation is a central contributor to the pathogenesis of cystic fibrosis (CF) pulmonary disease; so limiting the excessive production of inflammatory mediators represents a major therapeutic strategy for slowing the decline in lung function and improving survival. | 27922234 |
| Inflammation, Corneal edema, Unspecified visual loss | Altered Intercellular Communication | Diffuse corneal edema and anterior chamber inflammation prohibited any view to the posterior segment to identify the cause of her profound vision loss. | 27922461 |
| Inflammation, Primary malignant neoplasm, Neoplasm Metastasis | Altered Intercellular Communication | Matrix metalloproteinase-2 (gelatinase A) is a well-known mediator of cancer metastasis, but it is also thought to be involved in several aspects of cancer development, including cell growth and inflammation. | 27922483 |
| Myositis | Altered Intercellular Communication | LDK multifidus specimens revealed diffuse, nonuniform muscular fibers and growth of the interstitium and adipose tissue, with no muscular inflammation. | 27922574 |
| Inflammation | Altered Intercellular Communication | The rate of systemic inflammation in FG was 30.71%, which was the highest among three groups (P = 0.042). | 27923057 |
| Pain Distress Question, Inflammation, Neoplasms | Altered Intercellular Communication | The authors report the case of a 64-year-old male with a soft tissue mass in his right gluteal area that presented initially with right leg pain, then later with signs of inflammation on the tumor area. | 27923374 |
| Menopause | Altered Intercellular Communication | Does Inflammation Mediate Relationships Between Racial Identity and Onset of Menopause Among US Adults? | 27924623 |
| Inflammation | Altered Intercellular Communication | The advanced patient age, MCC, PSA, and chronic inflammation may be the important clinical predictors of persistent IDC. | 27924790 |
| Cerebral Amyloid Angiopathy, Inflammation | Altered Intercellular Communication | Histopathological examination demonstrated cerebral amyloid angiopathy with perivascular inflammation. | 27925301 |
| Inflammation, septic | Altered Intercellular Communication | The declined levels of serum inflammatory cytokines, especially IL-6, improved inflammation status might be one factor of successfully weaning during septic patients on ventilators. | 27925446 |
| Inflammation | Altered Intercellular Communication | This result may extend previous knowledge on close interactions between inflammation and arterial stiffening. | 27927628 |
| Infarction, Inflammation | Altered Intercellular Communication | Importantly, although there was no correlation with infarct size (r=0.03, p=0.90) or inflammation (C reactive protein, r=-0.20, p=0.38), 18F-fluciclatide uptake was increased in segments displaying functional recovery (TBRmean 0.95+-0.33 vs 0.81+-0.27, p=0.002) and associated with increase in probability of regional recovery. | 27927700 |
| Hepatic inflammation, Diabetes Mellitus, Kidney Diseases, Cardiovascular Diseases | Altered Intercellular Communication | HIV/HCV coinfection and elevated interleukin (IL)-18 levels are both associated with enhanced progression of hepatic inflammation and increased risk of diabetes, kidney disease, and cardiovascular disease. | 27927859 |
| Inflammation | Altered Intercellular Communication | Regulatory receptors expressed on monocytes and macrophages act to suppress cytokine production, and reduced expression of regulatory receptors may thus promote tissue inflammation. | 27929051 |
| Inflammation, Arachnoiditis, Pain Distress Question | Altered Intercellular Communication | Patterns of chronic inflammation in extensively treated patients with arachnoiditis and chronic intractable pain. | 27929717 |
| Inflammation, Chronic pain | Altered Intercellular Communication | To use biomarkers to gain insight into and gauge the residual (post-treatment) level of inflammation in two groups of intensively treated patients with severe chronic pain. | 27929717 |
| Inflammation, Astrocytoma, Toxoplasmosis | Altered Intercellular Communication | All patients were successfully sampled, and the histological results showed inflammation in 4 cases, toxoplasma gondii infection in 1 case, astrocytoma in 1 case, and abscess in 1 case. | 27930545 |
| Dilated Cardiomyopathy Pathway, Myocarditis | Altered Intercellular Communication | Comparison of Ventricular Inducibility with Late Gadolinium Enhancement and Myocardial Inflammation in Endomyocardial Biopsy in Patients with Dilated Cardiomyopathy. | 27930686 |
| Inflammation, Fibrosis Assessment | Altered Intercellular Communication | We could not find a significant association between inducibility and the degree of cardiac inflammation and fibrosis in non-site directed routine right ventricular endomyocardial biopsy. | 27930686 |
| Inflammation, Fibrosis Assessment, Ventricular arrhythmia | Altered Intercellular Communication | The presence of myocardial fibrosis or inflammation in undirected endomyocardial biopsy does not seem to be sufficient to predict future ventricular arrhythmias. | 27930686 |
| Inflammation | Altered Intercellular Communication | Endogenous hydrogen sulfide (H2S) has recently been shown to play an important role in inflammation, but the role of endogenous H2S in the human gingival tissue is unknown. | 27930932 |
| Chronic liver disease, Fibrosis Assessment, Inflammation | Altered Intercellular Communication | Overall 20 (87%) featured chronic liver disease characterized by a chronic inflammation and/or a significant portal fibrosis on histology. | 27931086 |
| Inflammation, Invasive Malignant Neoplasm, Neoplasm Metastasis, Neoplasms | Altered Intercellular Communication | Metalloproteinases (MMPs) are relevant modulators of inflammation, tumor microenvironment, cancer invasion and metastasis. | 27931798 |
| Axonal degeneration, Inflammation, Sensory neuropathy | Altered Intercellular Communication | Electrophysiological studies indicated primary axonal degeneration of peripheral motor and sensory fibers without inflammation. | 27932182 |
| Pain Distress Question, Inflammation | Altered Intercellular Communication | Overall both topical treatments were effective in alleviating pain and inflammation, as evidenced by decreases in pain and inflammation scores within 3 days after treatment initiation. | 27933598 |
| Pain Distress Question, Inflammation | Altered Intercellular Communication | DHEP mouthwash was at least as effective as diclofenac mouth-wash at alleviating pain and inflammation symptoms and is well tolerated in patients with painful inflammatory conditions of the oral cavity. | 27933598 |
| Pain Distress Question, Inflammation | Altered Intercellular Communication | DHEP mouthwash was at least as effective as diclofenac mouth-wash at alleviating pain and inflammation symptoms and is well tolerated in patients with painful inflammatory conditions of the oral cavity. | 27933598 |
| Inflammation, Chlamydia, Hypertrophy | Altered Intercellular Communication | Role of Chlamydia pneumoniae in the pathogenesis of hypertrophy and adenoid tissue inflammation in children. | 27935539 |
| Inflammation, Chlamydia, Hypertrophy of adenoids | Altered Intercellular Communication | A tropism to epithelial cells and lymphocytes, an inhibition of apoptosis in host cells, an ability to occurrence in persistent form resistant to antibiotic treatment are the features of Chlamydia pneumoniae, which can have connection with chronic inflammation of an adenoid tissue and adenoid hypertrophy. | 27935539 |
| Inflammation, Epithelial cyst | Altered Intercellular Communication | The histopathological findings confirm the diagnosis of an epidermoid cyst, characterized by the presence of: (I) a cyst cavity lined by stratified squamous epithelium with keratinization on the surface; and (II) connective tissue with a mild inflammation. | 27935912 |
| ARCN1 gene, Pneumonitis | Altered Intercellular Communication | MAP3K19 Is Overexpressed in COPD and Is a Central Mediator of Cigarette Smoke-Induced Pulmonary Inflammation and Lower Airway Destruction. | 27935962 |
| ARCN1 gene, Respiratory physiology, Chronic Obstructive Airway Disease | Altered Intercellular Communication | Chronic obstructive pulmonary disease (COPD) is characterized by persistent airflow limitation and lung inflammation resulting in a progressive decline in lung function whose principle cause is cigarette smoke. | 27935962 |
| Inflammation, Impaired cognition, ETV3 wt Allele | Altered Intercellular Communication | MetS patients had high levels of inflammation and a 3.542-fold increased odds ratio (OR) for cognitive impairment [95% confidence interval (CI): 1.972-6.361]. | 27936074 |
| Acute inflammation | Altered Intercellular Communication | This suggests that, if disturbances in melatonin secretion occur, these might occur after surgery due to postoperative inflammation. | 27936113 |
| Inflammation, Burn injury | Altered Intercellular Communication | Microvesicles are cell-derived signaling particles emerging as important mediators and biomarkers of systemic inflammation, but their production in severe burn injury patients has not been described. | 27936199 |
| Inflammation, Prostate carcinoma | Altered Intercellular Communication | Comparison of different contouring definitions of the rectum as organ at risk (OAR) and dose-volume parameters predicting rectal inflammation in radiotherapy of prostate cancer: which definition to use? | 27936891 |
| Inflammation | Altered Intercellular Communication | Acute or subacute rectal inflammation occurred in 69 (71.9%) patients in Cohort 1 and in 43 (70.5%) in Cohort 2. | 27936891 |
| Peripheral Vascular Diseases, Inflammation, Coronary Arteriosclerosis | Altered Intercellular Communication | Strong evidence implicates inflammation in the development of atherosclerotic heart disease but less is known about peripheral arterial disease (PAD). | 27938334 |
| Crohn Disease, Specimen Type - Fistula, Inflammation | Altered Intercellular Communication | Crohn's disease (CD) is characterized by transmural inflammation of the gastrointestinal tract, which predisposes to the formation of fistula. | 27939339 |
| Inflammation, Arthritis, Hypocalcemia | Altered Intercellular Communication | After 5 days, she had arthritis of the right wrist, laboratory evidence of systemic inflammation, and hypocalcemia. | 27939801 |
| Inflammation, Hypocalcemia | Altered Intercellular Communication | The features were similar to those in our patients, with a short time to onset, systemic inflammation in many cases, a tendency toward hypocalcemia, and radiographs that often showed evidence of CPDD. | 27939801 |
| Inflammation, Primary malignant neoplasm | Altered Intercellular Communication | The relationship between systemic inflammation and stoma formation following anterior resection for rectal cancer: A cross-sectional study. | 27940290 |
| Keratitis, Corneal edema | Altered Intercellular Communication | Because corneal inflammation and corneal edema improved, the protruding structures and high-intensity regions of posterior corneal images were resolved after a course of antiviral treatment. | 27941387 |
| ARCN1 gene, Inflammation, Chronic Obstructive Airway Disease | Altered Intercellular Communication | Chronic obstructive pulmonary disease (COPD) is more prevalent in HIV-infected individuals and is associated with persistent inflammation. | 27941393 |
| Cyst, Inflammation, Fibrous | Altered Intercellular Communication | Following excision, histology showed a cyst that contained keratin and lanugo hairs in its lumen with sebaceous glands and chronic inflammation in its fibrous wall. | 27941469 |
| Inflammation | Altered Intercellular Communication | iTRAQ-based proteomic profiling reveals that complement and coagulation cascades and inflammation may play important roles in the pathogenesis of RRDCD. | 27941623 |
| Inflammation, Demyelination, N-nitrosomorpholine | Altered Intercellular Communication | Hydroxycholesterols (OHCs), metabolites of CNS cholesterol, are involved in diverse cellular responses to inflammation and demyelination, and may also be involved in the pathogenesis of NMO. | 27942009 |
| Inflammation, Endothelial dysfunction, Chronic Kidney Diseases | Altered Intercellular Communication | Chorioretinal thinning in chronic kidney disease links to inflammation and endothelial dysfunction. | 27942587 |
| Arterial Stiffness, Inflammation | Altered Intercellular Communication | Finally, choroidal thinning was associated with renal histological inflammation and arterial stiffness. | 27942587 |
| Arterial Stiffness, Inflammation, Endothelial dysfunction | Altered Intercellular Communication | Similarly, the associations with arterial stiffness, inflammation, and endothelial dysfunction warrant further examination. | 27942587 |
| Inflammation, Malnutrition | Altered Intercellular Communication | Low circulating coenzyme Q10 during acute phase is associated with inflammation, malnutrition, and in-hospital mortality in patients admitted to the coronary care unit. | 27942805 |
| Poi serotype, Inflammation | Altered Intercellular Communication | The aim of this study was to investigate the relation of POI with inflammation and AL after colorectal resection. | 27943617 |
| Inflammation | Altered Intercellular Communication | The SASP secreted by accumulated senescent cells during old age has been related to local inflammation that leads to cellular transformation and therefore may be supporting the inflammaging process. | 27951455 |
| Inflammation | Altered Intercellular Communication | The SASP secreted by accumulated senescent cells during old age has been related to local inflammation that leads to cellular transformation and therefore may be supporting the inflammaging process. | 27951455 |
| Inflammation, Fatty degeneration | Altered Intercellular Communication | There were significant and strong associations between serum miR-122 ratio (ratio of level at second biopsy to that at first biopsy) and changes in histopathological scores (of steatosis, lobular inflammation, and stage). | 27955628 |
| Refractory anemias, Rheumatoid Arthritis, Inflammation, Degenerative polyarthritis | Altered Intercellular Communication | Diseases associated with human cartilage, including rheumatoid arthritis (RA) and osteoarthritis (OA) have manifested age, mechanical stresses and inflammation as the leading risk factors. | 27955675 |
| Chronic cerebrovascular accident, Inflammation | Altered Intercellular Communication | RT in chronic stroke induces changes in key skeletal muscle regulators of metabolism, without effecting circulating inflammation. | 27955950 |
| Arteritis | Altered Intercellular Communication | Coronary arterial inflammation (18F-fluorodeoxyglucose uptake, expressed as target-to-background ratio) was assessed in the left main coronary artery (LMCA). | 27956407 |
| Inflammation, Sympathetic Nervous System, Hypertension, CTCAE | Altered Intercellular Communication | Overactivation of renal sympathetic nervous system and low-grade systemic inflammation are common features of hypertension. | 27956575 |
| Inflammation, Endothelial dysfunction | Altered Intercellular Communication | However, we propose that keloids and hypertrophic scars are simply manifestations of the same skin FPD and differ only in the degree of endothelial dysfunction and therefore inflammation. | 27959277 |
| Schizophrenia | Altered Intercellular Communication | Cortical grey matter volume reduction in people with schizophrenia is associated with neuro-inflammation. | 27959331 |
| Deficit, Schizophrenia, negative regulation of urine volume | Altered Intercellular Communication | Cortical grey matter volume deficits and neuro-inflammation exist in patients with schizophrenia, although it is not clear whether elevated cytokines contribute to the cortical volume reduction. | 27959331 |
| Inflammation, Rheumatoid Arthritis, Pain Distress Question | Altered Intercellular Communication | Discordant inflammation and pain in early and established rheumatoid arthritis: Latent Class Analysis of Early Rheumatoid Arthritis Network and British Society for Rheumatology Biologics Register data. | 27964757 |
| Pain Distress Question, Central pain, Inflammation | Altered Intercellular Communication | In latent class analysis, we used variables related to pain, central pain mechanisms or inflammation (pain, vitality, mental health, erythrocyte sedimentation rate, swollen joint count, tender joint count, visual analogue scale of general health). | 27964757 |
| Inflammation, Primary malignant neoplasm | Altered Intercellular Communication | A high neutrophil-to-lymphocyte ratio (NLR) is a marker of systemic inflammation and is associated with poor survival in localized or metastatic cancer. | 27964892 |
| Primary malignant neoplasm | Altered Intercellular Communication | DNA Methylation-Derived Neutrophil-to-Lymphocyte Ratio: An Epigenetic Tool to Explore Cancer Inflammation and Outcomes. | 27965295 |
| Inflammation | Altered Intercellular Communication | Although high-mobility group box 1 (HMGB1) is involved in many aspects of inflammation, its role in sepsis-induced immune suppression remains unclear. | 27965385 |
| Inflammation | Altered Intercellular Communication | Vitamin D supplementation may contribute to reduced inflammation and improved lung function in CF. | 27966575 |
| Communicable Diseases, Inflammation | Altered Intercellular Communication | Furthermore, S2V was less virulent than the prototype strain VACV-Western Reserve (WR) in a murine model of intradermal infection, producing a tiny lesion with virtually no surrounding inflammation. | 27973399 |
| Inflammation, Atherosclerotic lesion | Altered Intercellular Communication | Vascularization was also increased in the upstream regions of advanced atherosclerotic lesions compared with downstream regions (4.6 vs. 1.4 vessels/mm2, p = 0.001) and was associated with intra-plaque hemorrhage and inflammation. | 27973542 |
| Inflammation | Altered Intercellular Communication | Vascularization is increased in the upstream regions of both early and advanced plaques and is in advanced lesions mainly driven by inflammation. | 27973542 |
| Airway structure | Altered Intercellular Communication | Fractional concentration of exhaled nitric oxide (FeNO) is recommended by the American Thoracic Society (ATS) as a noninvasive biomarker of airway inflammation. | 27973944 |
| Cessation of life | Altered Intercellular Communication | Tunneling nanotubes (TNTs) are intercellular communication structures involved in transport of cellular contents and pathogens, also demonstrated to play a role in both cell death modulation and chemoresistance. | 27974700 |
| Delirium | Altered Intercellular Communication | Simple enhancement of cholinergic neurotransmission may not be sufficient to treat delirium. | 27974719 |
| Prolactin Release-Inhibiting Hormone, Inflammation, Hyperpigmentation | Altered Intercellular Communication | Postinflammatory hyperpigmentation (PIH) is an acquired hyperpigmentation that involves areas of prior cutaneous inflammation. | 27976510 |
| Refractory anemias, Rheumatoid Arthritis | Altered Intercellular Communication | Rheumatoid arthritis (RA) is characterized by autoimmune chronic joint inflammation, which is worsened by mechanical stress. | 27976695 |
| Inflammation, Fibrosis Assessment, Pneumoconiosis | Altered Intercellular Communication | Inhaled dust leads to inflammation and fibrosis in the lungs, and coal workers' pneumoconiosis can be a debilitating disease. | 27977638 |
| Inflammation, Proteobacteria, Actinobacteria phylum | Altered Intercellular Communication | Inflammation explained 30-98% of the observed associations between levels of Actinobacteria, Proteobacteria or Firmicutes and insulin resistance (p-values < 0.05). | 27978598 |
| Inflammation | Altered Intercellular Communication | Eighteen individual taxa were associated with inflammation (p < 0.05) and 22 with insulin resistance (p < 0.05). | 27978598 |
| Multiple Organ Failure, Inflammation, Sepsis, Dyslipidemias, Liver Dysfunction, Diabetes Mellitus, Hypocalcemia, Hypokalemia, Systemic Inflammatory Response Syndrome, Chronic Kidney Diseases | Altered Intercellular Communication | In this study, systemic inflammation, sepsis, systemic inflammatory response syndrome (SIRS), multiple organic failure (MOF), chronic renal failure, liver dysfunction, mechanical ventilation, diabetes, dyslipidemia and impaired ion homeostasis (hypocalcaemia, hypokalemia) were associated with CIP. | 27978832 |
| Inflammation, Heart failure | Altered Intercellular Communication | Although heightened inflammation and autoimmune responses have been well described in patients with heart failure, the role of cell-mediated immune function in the pathogenesis and progression of heart failure is unclear. | 27979039 |
| Inflammation, Psoriasis, Inflammatory dermatosis | Altered Intercellular Communication | Psoriasis is a chronic inflammatory skin disease characterized by epidermal hyperproliferation and altered keratinocyte differentiation and inflammation and is caused by the interplay of genetic and environmental factors. | 27980695 |
| Inflammatory Bowel Diseases, Inflammation, Malignant Neoplasms | Altered Intercellular Communication | Both chronic inflammation and reduced immunosurveillance contribute to malignancy development in inflammatory bowel disease (IBD). | 27981298 |
| Inflammation, Hepatobiliary Disorder, Fibrosis Assessment | Altered Intercellular Communication | Histological severity of liver disease (inflammation, ballooning, and fibrosis) was not associated with the amount of IHTG content. | 27981615 |
| physiopathological, Decreased Libido | Altered Intercellular Communication | The "older" vignette's dysfunction was more likely to be attributed to hormonal changes, health problems and decreased sexual desire. | 27981728 |
| Juvenile-Onset Still Disease | Altered Intercellular Communication | Adult-onset Still's disease (AOSD) is an uncommon inflammatory condition of unknown origin. | 27981819 |
| Cereals, Having administered, Inflammation | Altered Intercellular Communication | Administered concurrently with a glucose bolus, the source of whole grains did not attenuate the post-prandial response of markers of glucoregulation and insulin sensitivity, inflammation, nor vascular remodeling compared to the refined grain control. | 27983687 |
| ARCN1 gene, neutrophilic, Asthma, Inflammation | Altered Intercellular Communication | The aim of this study was to analyze the neutrophilic and eosinophilic airway and systemic inflammation as the phenotypic characterization of patients with asthma and COPD. | 27983888 |
| ARCN1 gene, Airway structure | Altered Intercellular Communication | Asthma and COPD can be differentiated based on eosinophilic/neutrophilic systemic or airway inflammation with unsatisfactory efficiency. | 27983888 |
| Community acquired pneumonia | Altered Intercellular Communication | Community-acquired pneumonia (CAP) is characterized as an acute inflammation of the lung associated with the activation of macrophages and neutrophils. | 27983998 |
| Pneumonitis | Altered Intercellular Communication | Intercellular adhesion molecule-1 (ICAM-1) is an essential adhesion molecule involved in immune cell recruitment in lung inflammation. | 27983998 |
| vascular inflammations, Atherosclerosis | Altered Intercellular Communication | NADPH oxidase 4 regulates vascular inflammation in aging and atherosclerosis. | 27986445 |
| vascular inflammations, physiopathological, Atherosclerosis | Altered Intercellular Communication | We recently reported that increased NADPH oxidase 4 (NOX4) expression and activity during aging results in enhanced cellular and mitochondrial oxidative stress, vascular inflammation, dysfunction, and atherosclerosis. | 27986445 |
| Radiculitis, Palsy | Altered Intercellular Communication | Different hypotheses have been proposed for the pathophysiology of posterior interosseous nerve (PIN) palsy, namely compression, nerve inflammation, and fascicular constriction. | 27986526 |
| Inflammation, COL4A2 wt Allele, Cerebral Hemorrhage | Altered Intercellular Communication | Reducing excessive inflammation is beneficial for the recovery from intracerebral hemorrhage (ICH). | 27986908 |
| Inflammatory, Inflammation | Altered Intercellular Communication | These results suggested that A20 is involved in regulating ICH-induced inflammatory injury in both the central and peripheral system and that A20 reduces ICH-induced inflammation by regulating TRAF6 polyubiquitination. | 27986908 |
| Inflammation, Prostate Imaging-Reporting and Data System | Altered Intercellular Communication | Inflammation was found in 36 (58%) PIRADS 3 lesions, 24 (39%) PIRADS 4 lesions and 2 (3%) PIRADS 5 lesions on pre biopsy MRI evaluation. | 27987276 |
| Inflammation, Prostate Imaging-Reporting and Data System | Altered Intercellular Communication | In our series, biopsies which showed inflammation had a radiological appearance on mpMRI more likely of a PIRADS 3 or 4 lesions with only 3% of PIRADS 5 biopsies showing inflammation. | 27987276 |
| Inflammation, Electrocardiogram: myocardial infarction (finding), Blood Clot | Altered Intercellular Communication | To compare angiographic and optical coherence tomography (OCT) data pertinent to thrombi, along with the histologic characteristics of aspirated thrombi in patients presenting with ST elevation myocardial infarction (STEMI) with or without inflammation, as assessed by C-reactive protein (CRP) and myeloperoxidase (MPO). | 27988513 |
| Inflammation, Psoriasis, Arthritis, Psoriatic | Altered Intercellular Communication | Among patients with psoriasis no significant correlations with the disease activity and inflammation markers were observed and only patients with psoriatic arthritis had significantly higher CER total concentration. | 27988894 |
| Inflammatory disease of mucous membrane | Altered Intercellular Communication | Surgery should be as close as possible to displacement in order to minimise mucosal inflammation and to prevent unnecessary manipulation during surgical removal. | 27990509 |
| Malignant Peripheral Nerve Sheath Tumor, Inflammation, Myeloproliferative disease | Altered Intercellular Communication | It has been reported that chronic inflammation may be an important driving force for myeloproliferative neoplasms (MPNs). | 27990849 |
| Inflammation, Thrombocytosis | Altered Intercellular Communication | Therefore, we hypothesized that as an important inflammation regulator, TIM-3 may be involved in essential thrombocythaemia (ET). | 27990849 |
| Edema | Altered Intercellular Communication | Muscle oedema on fat-suppressed MRI sequences is thought to represent active inflammation. | 27991408 |
| Inflammation | Altered Intercellular Communication | Systemic inflammation has been linked to suppressed CYP3A(4) activity. | 27991741 |
| Inflammation, Comorbidity | Altered Intercellular Communication | There were no differences in nutrition, comorbidity, and inflammation indices among the patients with different non-HDL groups. | 27992532 |
| Nephritis | Altered Intercellular Communication | These results suggest that urine OPN N-half concentration reflects renal inflammation. | 27992535 |
| Uremia, Inflammation, Atherosclerosis | Altered Intercellular Communication | In this study, we investigated the expression of Lp-PLA2 on leucocytes and different monocyte subpopulations and their possible role in uremia, inflammation, and atherosclerosis. | 27992874 |
| Allergic sensitization, Inflammation, Noncommunicable Diseases | Altered Intercellular Communication | Systemic low-grade inflammation has been demonstrated in a range of the frequent noncommunicable diseases (NCDs) proposing a shared mechanism, but is largely unexplored in relation to allergic sensitization. | 27992959 |
| Allergic sensitization, Inflammation | Altered Intercellular Communication | Elevated hs-CRP is associated with allergic sensitization in school-aged children suggesting systemic low-grade inflammation as a phenotypic characteristic of this early-onset NCD. | 27992959 |
| Myeloid | Altered Intercellular Communication | Nutritional Wheat Amylase-Trypsin Inhibitors Promote Intestinal Inflammation via Activation of Myeloid Cells. | 27993525 |
| Pancreatitis | Altered Intercellular Communication | Orally ingested ATIs are largely resistant to proteases and heat, and increase intestinal inflammation by activating gut and mesenteric lymph node myeloid cells. | 27993525 |
| Inflammation, HDL Phospholipid Measurement, ETV3 wt Allele | Altered Intercellular Communication | Low HDL-P is independently associated with incident MetS after adjustment for traditional risk factors, lipid parameters, adiposity, inflammation, and markers of insulin resistance. | 27993539 |
| Pigmentation, Retinitis Pigmentosa, Vitreous inflammatory cells | Altered Intercellular Communication | Twenty-five patients were identified by characteristic symptoms (abrupt onset of photopsias, followed by large scotomata at or connected to the blind spot), ocular findings (paucity of pigmentary changes with no sign of vitreous inflammation and abnormal electroretinogram in at least 1 eye), and a negative family history for retinitis pigmentosa. | 27993590 |
| Inflammation, Calcification of coronary artery, Carotid Intima-Media Thickness, Atherosclerosis, Peripheral Vascular Diseases | Altered Intercellular Communication | This study assesses the impact of SHS on inflammation and atherosclerosis (carotid intima-media thickness, coronary artery calcification, and peripheral arterial disease). | 27993830 |
| Inflammation, Carotid Intima-Media Thickness | Altered Intercellular Communication | Urinary cotinine was not associated with inflammation or carotid intima-media thickness. | 27993830 |
| Peripheral Vascular Diseases, Inflammation | Altered Intercellular Communication | Despite limited exposure assessment, this study supports the association of SHS exposure with inflammation and peripheral arterial disease. | 27993830 |
| Adenomatous polyp of colon, Chronic Kidney Diseases, Diabetes Mellitus | Altered Intercellular Communication | Adenomatous Colon Polyps in Diabetes: Increased Prevalence in Patients with Chronic Kidney Disease and Its Association with Parathyroid Hormone. | 27993873 |
| Inflammation, Coronary microvascular dysfunction | Altered Intercellular Communication | Uric Acid Is Associated With Inflammation, Coronary Microvascular Dysfunction, and Adverse Outcomes in Postmenopausal Women. | 27993955 |
| Inflammation, Hyperlipidemia | Altered Intercellular Communication | Association of Beta-2 Microglobulin with Inflammation and Dislipidemia in High-Flux Membrane Hemodialysis Patients. | 27994294 |
| Bone Diseases, Inflammation, Dyslipidemias | Altered Intercellular Communication | In high-flux membrane hemodialysis patients, we observed a significant relationship of b2M with dyslipidemia and mineral bone disorders, but there was no correlation with inflammation. | 27994294 |
| Inflammatory abnormality of the eye, Dislocations | Altered Intercellular Communication | Five weeks later, ocular inflammation subsided following posterior dislocation of the cataractous lens, thus revealing the error in our initial diagnosis. | 27994397 |
| Refractory anemias, vascular inflammations | Altered Intercellular Communication | Accordingly, resistive index (RI) on spectral Doppler (sD) US provides a quantitative analysis of vascular inflammation, but its utility in the evaluation of RA activity has not been established. | 27995383 |
| Inflammation | Altered Intercellular Communication | The pixel-based CEUS assessment is a truly measure synovial inflammation, as a useful tool to develop quantitative imaging biomarker for monitoring target therapeutics in PsA. | 27995384 |
| Inflammation | Altered Intercellular Communication | In summary, our results demonstrate the role of inflammation and oxidative stress in age-related changes of immune cell survival factors in the BM, suggesting that antioxidants may be beneficial in counteracting immunosenescence by improving immunological memory in old age. | 27995612 |
| Airway structure | Altered Intercellular Communication | Fractional exhaled nitric oxide (FENO) levels were measured to assess airway inflammation. | 27996287 |
| Inflammation, Biliary calculi, Mirizzi Syndrome, Cholecystolithiasis, MS gene | Altered Intercellular Communication | Mirizzi syndrome (MS) is a rare complication of cholecystolithiasis that causes compacted gallstones and is often accompanied by severe inflammation of Calot's triangle. | 27996365 |
| Neoplasms | Altered Intercellular Communication | DAAs Rapidly Reduce Inflammation but Increase Serum VEGF Level: A Rationale for Tumor Risk during Anti-HCV Treatment. | 27997563 |
| Inflammation, Muscular Dystrophy | Altered Intercellular Communication | The results indicate that genetic reduction of p65 levels diminished chronic inflammation in dystrophic muscle, thus leading to amelioration of muscle pathology and improved muscle physiological function. | 27997693 |
| Degenerative polyarthritis, Inflammation, Synovitis | Altered Intercellular Communication | Associations Between Clinical Evidence of Inflammation and Synovitis in Symptomatic Knee Osteoarthritis: A Cross-Sectional Substudy. | 27998036 |
| Degenerative polyarthritis, Arthritis | Altered Intercellular Communication | Painful knee osteoarthritis (KOA) has been associated with joint inflammation. | 27998036 |
| Inflammation, Clinical Events Domain | Altered Intercellular Communication | This study examined the relationship between clinical and functional markers of localized knee inflammation and CE MRI-based synovial scores. | 27998036 |
| Inflammation, Pain Distress Question, Stiffness, Sore to touch, effusion | Altered Intercellular Communication | In this cross-sectional substudy, associations between validated MRI-based semiquantitative synovial scores of the knee and the following markers of inflammation were investigated: self-reported pain and stiffness, effusion, warmth, joint line tenderness, erythrocyte sedimentation rate, radiographic severity, and functional ability tests. | 27998036 |
| Suppuration, Pain Distress Question, Inflammation, Ulceration, CTCAE | Altered Intercellular Communication | A 78-year-old woman of African descent presented with pain, inflammation, suppuration, ulceration, and deformation of digits of all four limbs. | 27998311 |
| Inflammation, Periprosthetic osteolysis | Altered Intercellular Communication | Evidence suggests that wear particles induce inflammation causing periprosthetic osteolysis contributing to implant loosening with wear rates of 0.05 mm/y were considered safe. | 27998657 |
| Osteoblastoma, Bone lesion, Inflammation, Malignant Neoplasms | Altered Intercellular Communication | The final diagnosis was established by CT-guided biopsy of both the bone lesion and the paraspinal soft tissue, which excluded malignancy and revealed an osteoblastoma surrounded by plasma cell-rich chronic inflammation. | 27999873 |
| Cerebral Amyloid Angiopathy, "Alzheimers Disease", Inflammation, Cerebral microbleeds | Altered Intercellular Communication | Comparison of cerebrospinal fluid profiles in Alzheimer's disease with multiple cerebral microbleeds and cerebral amyloid angiopathy-related inflammation. | 28000005 |
| Cerebral Amyloid Angiopathy, Inflammation, "Alzheimers Disease", Hyperintensity of cerebral white matter on MRI, Data types - Address, Cerebral microbleeds | Altered Intercellular Communication | Brain magnetic resonance imaging (MRI) of patients with Alzheimer's disease (AD) sometimes reveals multiple cerebral microbleeds (CMBs) and confluent white matter hyperintensities (WMHs) similar to those observed in cerebral amyloid angiopathy-related inflammation (CAA-I). | 28000005 |
| Gastrointestinal inflammation | Altered Intercellular Communication | These drugs have led to prolonged survival but can also result in autoimmune-type side effects, including gastrointestinal inflammation. | 28000302 |
| Inflammation, Electrocardiogram: myocardial infarction (finding) | Altered Intercellular Communication | Dipeptidyl peptidase-4 (DPP4) is an important regulator of incretins and inflammation, and it is involved in the pathophysiological process of myocardial infarction (MI). | 28000723 |
| Squamous cell carcinoma of esophagus | Altered Intercellular Communication | Systemic Immune-Inflammation Index Predicts Prognosis of Patients with Esophageal Squamous Cell Carcinoma: A Propensity Score-matched Analysis. | 28000729 |
| Neoplasms | Altered Intercellular Communication | Systemic immune-inflammation index (SII), based on peripheral lymphocyte, neutrophil, and platelet counts, was recently investigated as a prognostic marker in several tumors. | 28000729 |
| Inflammation, Fibrosis Assessment | Altered Intercellular Communication | These findings suggest that long-term lymphatic volume overload can induce chronic tissue inflammation, progressive fibrosis, impaired homeostasis, altered remodelling of adipose tissue, impaired regenerative capacity and immunological dysfunction. | 28000916 |
| Inflammation | Altered Intercellular Communication | As eosinophils typically accumulate at sites that are relatively hypoxic, particularly during periods of inflammation, these findings may have important implications to understanding the behaviour of these cells in vivo. | 28000962 |
| Morphology Findings Domain, Inflammation | Altered Intercellular Communication | This case enlights intriguing links between adipogenesis, inflammation and dysmorphology. | 28002528 |
| Inflammation, Hamartoma | Altered Intercellular Communication | From a practical point of view, finding and treating an over-imposed inflammation could help limit damage in a hamartomatous syndrome. | 28002528 |
| Inflammatory disorder | Altered Intercellular Communication | Toll-like receptor 4 (TLR4) is a key modulator in many inflammation-related diseases. | 28002812 |
| Inflammation | Altered Intercellular Communication | Our data provide evidence that polySia avDP20 ameliorates laser-induced damage in the retina and thus is a promising candidate to prevent AMD-related inflammation and angiogenesis. | 28003336 |
| Inflammation, Cerebrovascular accident | Altered Intercellular Communication | Inflammation plays a crucial role in the pathogenesis of stroke. | 28004340 |
| methyldopa, Inflammation | Altered Intercellular Communication | Amyloid b (Ab)-induced chronic inflammation is believed to be a key pathogenic process in early-stage age-related macular degeneration (AMD). | 28004443 |
| ARCN1 gene, Inflammation | Altered Intercellular Communication | As COPD is associated with systemic inflammation, we determined whether smoking status is related to serum levels of matrix metalloproteinase-9 (pro- and active MMP-9), neutrophil gelatinase-associated lipocalin (NGAL) and the proMMP-9/NGAL complex in patients with COPD. | 28004483 |
| ARCN1 gene, Inflammation | Altered Intercellular Communication | Our results suggest that associated serum levels of proMMP-9, NGAL, proMMP-9/NGAL and NE may reflect the state of systemic inflammation in COPD related to cigarette smoking. | 28004483 |
| Coughing, Acid reflux, Bronchial Hyperreactivity, Airway structure | Altered Intercellular Communication | Chronic cough is one of the most common clinical problems and it may be secondary to different stimuli and diseases, including low-level physical and chemical stimulation of the esophageal-bronchial reflex, suggestive of cough-reflex hyperresponsiveness, in patients with gastroesophageal reflux; however, it is still debated whether gastroesophageal reflux could induce airway inflammation and acidification. | 28004646 |
| Coughing, Inflammation, Acid reflux | Altered Intercellular Communication | This study adds knowledge on possible mechanisms related to chronic cough associated with gastroesophageal reflux, which seems to be strictly dependent on airway acidification and the production of Cys-LTs, therefore suggesting an underlying neurogenic inflammation with tachykinins involvement. | 28004646 |
| Autoimmune Diseases, Inflammation, Rheumatoid Arthritis, Refractory anemias | Altered Intercellular Communication | Th17 and TfH cells are thought to promote tissue inflammation and autoantibody production, respectively, in autoimmune diseases including rheumatoid arthritis (RA). | 28004828 |
| Inflammation, Intervertebral Disc Degeneration | Altered Intercellular Communication | Inflammation is thought to have a major role in the pathogenesis of disc degeneration. | 28005398 |
| Airway structure, Fibrosis Assessment | Altered Intercellular Communication | Digitoxin for Airway Inflammation in Cystic Fibrosis: Preliminary Assessment of Safety, Pharmacokinetics, and Dose Finding. | 28006108 |
| Airway structure, Communicable Diseases, Fibrosis Assessment, Colonization | Altered Intercellular Communication | Cystic fibrosis (CF) lung disease progresses by a combination of airway inflammation, bacterial colonization, and infection. | 28006108 |
| Sepsis, Cessation of life, Cardio-Renal Syndrome, Inflammation | Altered Intercellular Communication | Cardiorenal Syndrome Type 5 in Sepsis: Role of Endotoxin in Cell Death Pathways and Inflammation. | 28006779 |
| Cell Death, Inflammation, septic | Altered Intercellular Communication | In this study, we investigated the possible relationship between endotoxin levels, renal cell death and inflammation in septic patients with CRS Type 5. | 28006779 |
| Inflammation, Apoptosis | Altered Intercellular Communication | Furthermore, this study highlights the presence of renal apoptosis, the immune deregulation and the strong inflammation in CRS Type 5 patients, especially in those with high endotoxin activity. | 28006779 |
| Pancreatitis, Acute, Pancreatitis | Altered Intercellular Communication | The predictive accuracy of individual markers, extrapancreatic inflammation on computed tomography (EPIC), acute physiology and chronic health evaluation II (APACHE II), and bedside index for severity in acute pancreatitis (BISAP) scores were measured using the area under the receiver operating characteristic curve (AUROC). | 28007685 |
| Kidney Failure, Chronic, vascular inflammations | Altered Intercellular Communication | Effect of omega-3 fatty acid supplementation on serum lipids and vascular inflammation in patients with end-stage renal disease: a meta-analysis. | 28008943 |
| Kidney Failure, Chronic, vascular inflammations | Altered Intercellular Communication | However, this association in patients with end-stage renal disease (ESRD) remains controversial prompting the need for investigation into the role of O3FAs on serum lipids and vascular inflammation markers. | 28008943 |
| Kidney Failure, Chronic, vascular inflammations | Altered Intercellular Communication | PubMed, EmBase, and the Cochrane Library were searched to identify randomized controlled trials (RCTs) focused on serum lipids and vascular inflammation markers in patients with ESRD. | 28008943 |
| Kidney Failure, Chronic, vascular inflammations | Altered Intercellular Communication | O3FA supplementation is associated with lower several serum lipids and vascular inflammation markers in patients with ESRD. | 28008943 |
| Inflammation | Altered Intercellular Communication | The Toll-like receptor plays an essential role in controlling immunity and inflammation. | 28009434 |
| Pneumonitis | Altered Intercellular Communication | We aimed to identify the role of the enzyme acid sphingomyelinase in the aging of stored units of packed red blood cells (pRBCs) and subsequent lung inflammation after transfusion. | 28009749 |
| Pneumonitis | Altered Intercellular Communication | Large volume pRBC transfusions are associated with multiple adverse clinical sequelae, including lung inflammation. | 28009749 |
| Pneumonitis | Altered Intercellular Communication | Microparticles are formed in stored pRBCs over time and have been shown to contribute to lung inflammation after transfusion. | 28009749 |
| Pneumonitis | Altered Intercellular Communication | Transfusion of aged pRBCs or microparticles isolated from aged blood into mice caused lung inflammation. | 28009749 |
| Inflammation, Carcinogenesis | Altered Intercellular Communication | INTRODUCTION Myeloid-derived suppressor cells (MDSCs) have the potent ability to suppress T-cell function, and are important in the regulation of chronic inflammation and carcinogenesis. | 28009997 |
| ARCN1 gene, Inflammation | Altered Intercellular Communication | CONCLUSIONS MDSCs are present in human lung microenvironment and may be involved in local inflammation in COPD. | 28009997 |
| ARCN1 gene, Inflammation | Altered Intercellular Communication | Future studies should focus on a detailed assessment of MDSCs in local and systemic inflammation in COPD. | 28009997 |
| Carcinogenesis, Hepatitis, fibrogenesis | Altered Intercellular Communication | During liver inflammation, triggering fibrogenesis and carcinogenesis immune cells play a pivotal role. | 28011329 |
| Liver carcinoma, Hepatitis, Chronic, FAM126A gene | Altered Intercellular Communication | In the present study we investigated the role of CCL5 in human and in murine models of chronic liver inflammation leading to hepatocellular carcinoma (HCC) development. | 28011329 |
| Chronic liver disease, Inflammation, Lymphoproliferative Disorder of the Skin, FAM126A gene | Altered Intercellular Communication | CCL5 expression and its receptors were studied in well-defined patients with chronic liver disease (CLD) and in two murine inflammation based HCC models. | 28011329 |
| Inflammation, Fibrosis Assessment, Neoplasms | Altered Intercellular Communication | The role of CCL5 in inflammation, fibrosis, tumor initiation and progression was analyzed in different cell populations of NEMODhepa/CCL5-/- animals and after bone marrow transplantation (BMT). | 28011329 |
| Cardiac Hypertrophy, Fibrosis Assessment, Inflammation | Altered Intercellular Communication | Transgenic overexpression of macrophage matrix metalloproteinase-9 exacerbates age-related cardiac hypertrophy, vessel rarefaction, inflammation, and fibrosis. | 28011588 |
| Inflammation | Altered Intercellular Communication | This led to a mismatch in the muscle-to-vessel ratio and resulted in increased cardiac inflammation. | 28011588 |
| TG gene, Inflammation | Altered Intercellular Communication | The increase in cardiac inflammation resulted in greater accumulation of interstitial collagen in TG (P < 0.05). | 28011588 |
| Cardiac Hypertrophy, Fibrosis Assessment, Inflammation | Altered Intercellular Communication | In conclusion, overexpression of MMP-9 in macrophages resulted in exacerbated cardiac hypertrophy in the setting of vessel rarefaction, which resulted in enhanced inflammation and fibrosis to augment the cardiac-aging phenotype. | 28011588 |
| Cardiac Hypertrophy, Fibrosis Assessment, Inflammation | Altered Intercellular Communication | We found that an elevation in macrophage-derived MMP-9 induced a greater age-dependent cardiac hypertrophy and vessel rarefaction phenotype, which enhanced cardiac inflammation and fibrosis. | 28011588 |
| Inflammation | Altered Intercellular Communication | In 21 patients undergoing carotid endarterectomy, carotid inflammation was evaluated by both FDG positron emission/computed tomography (FDG-PET/CT) imaging and MWR measurements. | 28011672 |
| Inflammation | Altered Intercellular Communication | Carotid inflammation was assessed by PET/CT as target-to-background ratio (TBR) by obtaining measurements in consecutive axial slices 2 cm below to 2 cm above the carotid bifurcation. | 28011672 |
| Ischemia, vascular inflammations, Endothelial dysfunction | Altered Intercellular Communication | We hypothesised that patterns of circulating biomarkers that reflect the various pathophysiological components of CAD, such as distorted lipid metabolism, vascular inflammation, endothelial dysfunction, increased thrombogenicity and ischaemia, diverge in the days to weeks before a coronary event. | 28011810 |
| Inflammation, Fibrosis Assessment, Atrial Fibrillation by ECG Finding | Altered Intercellular Communication | Chronic inflammation in the atrial myocardium was shown to play an important role in the development of atrial fibrosis in patients with atrial fibrillation (AF). | 28011843 |
| Inflammation, Fibrosis Assessment, Cardiovascular system | Altered Intercellular Communication | Histological signs of chronic inflammation affecting ventricular myocardium are strongly associated with AF and demonstrate significant correlation with fibrosis extent that cannot be explained by cardiovascular comorbidities otherwise. | 28011843 |
| Inflammation, Non-alcoholic Fatty Liver Disease, Obesity | Altered Intercellular Communication | Low-grade chronic inflammation emerges as a potent driver of insulin resistance and glucose dysregulation in obesity and associated non-alcoholic fatty liver disease (NAFLD). | 28011892 |
| Inflammation, Fatty degeneration | Altered Intercellular Communication | Hepatocyte-specific, but not adipose tissue-specific deletion of Ifnar1 worsened steatosis and inflammation induced by the MCD diet. | 28011892 |
| Inflammation, Organomegaly, Gaucher Disease | Altered Intercellular Communication | These factors contribute to defective deposition and clearance of apoptotic cells in phagolysosomes, which may have an impact on the inflammatory response and contribute to the organomegaly and inflammation seen in patients with Gaucher disease. | 28011901 |
| Inflammation, HIV | Altered Intercellular Communication | Cytomegalovirus Acquisition and Inflammation in Human Immunodeficiency Virus-Exposed Uninfected Zimbabwean Infants. | 28011912 |
| Inflammation, HIV | Altered Intercellular Communication | Cytomegalovirus (CMV) acquisition and inflammation were evaluated in 231 human immunodeficiency virus (HIV)-exposed uninfected (HEU) and 100 HIV-unexposed Zimbabwean infants aged 6 weeks. | 28011912 |
| Inflammation, Diabetes Mellitus, Cyclophosphamide/Vincristine/Dacarbazine Regimen, Cardiovascular Diseases | Altered Intercellular Communication | Low-grade inflammation is involved in the development of diabetes and cardiovascular disease (CVD). | 28012280 |
| Inflammation | Altered Intercellular Communication | Generally, the available data suggest a neutral role of dairy product consumption on inflammation. | 28012280 |
| Pneumonitis, Pneumonia | Altered Intercellular Communication | Organizing pneumonia (OP) is a histopathological response pattern to lung inflammation. | 28012487 |
| Inflammation, Retinitis Pigmentosa, polychondritis | Altered Intercellular Communication | Relapsing polychondritis (RP) is characterized by recurrent systemic inflammation of the cartilages and is accompanied by central airway collapse. | 28012498 |
| Fibrosis Assessment, Gastrointestinal inflammation, Intestinal Diseases | Altered Intercellular Communication | Fecal calprotectin (FC) is used to asses the presence of intestinal inflammation also in patients with Cystic Fibrosis (CF) and recent studies showed a correlation between bowel and lung disease in these patients. | 28012584 |
| Inflammation, Tissue damage, Inflammatory disorder, Choline Dehydrogenase, Mitochondrial, Dental Plaque | Altered Intercellular Communication | It is now widely accepted that CHD is an inflammatory disease and that macrophages within plaque together with tissue damage contribute to this inflammation. | 28012609 |
| Inflammation, Primary malignant neoplasm, FAM126A gene | Altered Intercellular Communication | The gene expression of FNDC5/Irisin, associated to key regulators of DNL, inflammation and cancer progression was evaluated in liver tissue of 18 patients with HCC undergoing liver transplantation and of 18 deceased donors. | 28012856 |
| Endothelial dysfunction | Altered Intercellular Communication | Here, we suggest that acute DEP exposure produces intracellular reactive oxygen species (ROS) leading to induction of DEP internalization, endothelial dysfunction, and pro-inflammation in an in vitro human umbilical vein endothelial cells (HUVEC) model. | 28013216 |
| Inflammation, TMPRSS11D gene, Trypanosomiasis | Altered Intercellular Communication | Inhibition of this pathway ameliorates CNS inflammation in rodent models of the late (meningoencephalitic) stage of human African trypanosomiasis (HAT). | 28013248 |
| Inflammation, Atherosclerosis | Altered Intercellular Communication | Chronic low grade inflammation is a common background for atherosclerosis development; however, increased plaque inflammation may predispose by itself to PR. | 28013285 |
| Inflammation | Altered Intercellular Communication | In the last decade, studies performed by optical coherence tomography (OCT) have allowed to establish the severity of plaque inflammation by assessing macrophage infiltration (MOI). | 28013285 |
| Pain Distress Question, Inflammation | Altered Intercellular Communication | Opiorphin is a pentapeptide isolated from human saliva that suppresses pain from chemically induced inflammation and acute physical pain. | 28013436 |
| Inflammation, Cardiovascular Diseases | Altered Intercellular Communication | Monocyte and monocyte to high-density lipoprotein ratio (MHR) recently emerged as markers of inflammation and have been reported to be novel prognostic indicators of cardiovascular diseases. | 28017204 |
| Inflammation, Diabetes Mellitus | Altered Intercellular Communication | Chronic inflammation plays a central role in the development and progression of diabetes, and in the pathogenesis of its complications. | 28017281 |
| Inflammation | Altered Intercellular Communication | The neutrophil-lymphocyte ratio (NLR) and platelet-lymphocyte ratio (PLR) are indicators of subclinical inflammation. | 28017281 |
| Prediabetes syndrome, diabetic | Altered Intercellular Communication | Inflammation marker NLR significantly increases in prediabetic and diabetic patients. | 28017281 |
| Cessation of life, Inflammation, Chronic Kidney Diseases | Altered Intercellular Communication | Inflammation and elevated levels of fibroblast growth factor 23 are independent risk factors for death in chronic kidney disease. | 28017325 |
| Inflammation, Chronic Kidney Diseases | Altered Intercellular Communication | Inflammation is a consequence of chronic kidney disease (CKD) and is associated with adverse outcomes in many clinical settings. | 28017325 |
| Chronic Kidney Diseases | Altered Intercellular Communication | Inflammation stimulates production of fibroblast growth factor 23 (FGF23), high levels of which are independently associated with mortality in CKD. | 28017325 |
| Cessation of life, Inflammation, Chronic Kidney Diseases | Altered Intercellular Communication | Few large-scale prospective studies have examined inflammation and mortality in patients with CKD, and none tested the interrelationships among inflammation, FGF23, and risk of death. | 28017325 |
| Traditional Serrated Adenoma, Inflammation, Dysplasia, Duodenal Cancer, Ulcer, Hyperplastic Polyp, Serrated Nodule | Altered Intercellular Communication | Serrated lesions were found in different mucosal lesions, with 14 lesions were detected in polyps (8 hyperplastic polyps and 6 serrated adenomas with low grade dysplasia), 3 detected in Menetrier gastropathy, 3 detected in an area of inflammation or ulcer, and 1 detected in the intramucosal carcinoma of the duodenum. | 28018111 |
| Inflammation, Impaired cognition, Dental Plaque | Altered Intercellular Communication | In summary, deficient daily oral hygiene, evidenced by greater bacterial dental plaque accumulation and gingival inflammation, is independently associated with cognitive impairment, even at its earliest stage. | 28024093 |
| Inflammation | Altered Intercellular Communication | Moreover, we compared inflammation in the EMB sampling area of the LVPW to the remaining myocardium of the LVPW and observed a significant increase of CD45+CD68 cells per mm2 in patients with LM. | 28025077 |
| Pain Distress Question, Breast Implant-Related Lesion | Altered Intercellular Communication | Two patients (one with inflammation-induced pain, one with implant-related pain) developed prolonged postoperative allodynia requiring pain-relief medication. | 28025370 |
| High Density Lipoproteins, Loss, Trauma, Nervous System | Altered Intercellular Communication | In HDLS cases, MRS revealed decreased NAA and Glu concentrations, which probably reflected neuronal damage and/or loss, and a subsequent reduction of neurotransmitters. | 28025469 |
| Granulomatous inflammation, Tuberculosis | Altered Intercellular Communication | The histologic examination revealed granulomatous inflammation consistent with tuberculosis. | 28025474 |
| Craniosynostosis | Altered Intercellular Communication | The sino-nasal disease chronic rhinosinusitis (CRS) is primarily an inflammatory condition that manifests in several ways. | 28025987 |
| Encephalitis, Inflammation, LGI1 protein, human | Altered Intercellular Communication | Leucine-rich glioma-inactivated1 (LGI1) encephalitis is an antibody-associated inflammation of the limbic area. | 28026046 |
| Prostate carcinoma, Neoplasms | Altered Intercellular Communication | Further supporting a role of inflammation-induced immune-suppression in the development of early-onset prostate cancer, we observed significant up-regulation of CTLA4 and IDO1/TDO2 pathways in tumors of the young cohort. | 28027300 |
| Carcinogenic Chlorinated Hydrocarbon, Fibrosis Assessment, Inflammation | Altered Intercellular Communication | Ang2 levels were significantly higher in the liver of CHC patients compared to controls and significantly correlated with inflammation and fibrosis. | 28027429 |
| Inflammation, Nodular lymphoid hyperplasia, Irritable Bowel Syndrome | Altered Intercellular Communication | Nodular lymphoid hyperplasia: A marker of low-grade inflammation in irritable bowel syndrome? | 28028368 |
| Abdominal bloating, Inflammation, Lactose Intolerance, Diarrhea, Abdominal Pain, Dermatitis, Ichthyosis Bullosa of Siemens | Altered Intercellular Communication | NLH cases shared some distinctive clinical features among IBS patients: they were younger, more often female, and had a higher frequency of abdominal pain, bloating, diarrhoea, unspecific inflammation, self-reported lactose intolerance and metal contact dermatitis. | 28028368 |
| Inflammatory Bowel Diseases, Inflammation, Ichthyosis Bullosa of Siemens | Altered Intercellular Communication | About 1/3 of patients with IBS-type symptoms or suspected IBD presented diffuse colonic NLH, which could be a marker of low-grade inflammation in a conspicuous subset of IBS patients. | 28028368 |
| Inflammation, Thrombosis, Cerebrovascular accident, ASAH1 gene, Subarachnoid Hemorrhage, Aneurysmal | Altered Intercellular Communication | Inflammation and thrombosis are associated with the pathogenesis of aneurysmal subarachnoid hemorrhage (aSAH) and neutrophil to lymphocyte ratio (NLR) and platelet to lymphocyte ratio (PLR) are emerging as novel inflammatory markers in stroke. | 28028791 |
| Thrombosis | Altered Intercellular Communication | This risk is apparent in patients with imminent GCA unexposed to oral glucocorticoids, suggesting a role for inflammation-associated thrombosis that is independent of glucocorticoid use. | 28029234 |
| Inflammation, Asthma, Sinusitis | Altered Intercellular Communication | In adults with asthma, CT imaging evidence of severe sinusitis indicates intense Th2-related inflammation, regardless of smoking status. | 28029801 |
| Inflammation, Perforation (observation) | Altered Intercellular Communication | A 24-year-old male with a left conchal inflammation and perforation visited our plastic surgery department after receiving augmentation rhinoplasty and tip plasty using a conchal cartilage graft. | 28032171 |
| Inflammation, Coronary Artery Disease | Altered Intercellular Communication | These data indicate that genetic variation within the CR1 gene is associated with inflammation and the risk of incident coronary artery disease. | 28033544 |
| Late onset asthma, selenium, Inflammation | Altered Intercellular Communication | SE sensitization contributes to TH2 inflammation in nonatopic and/or late-onset asthma. | 28034578 |
| Inflammation, Failure (biologic function), Uveitis | Altered Intercellular Communication | Main outcome measures were failure of complete resolution of uveitis or recurrence of inflammation. | 28035499 |
| Inflammation, Fibrosis Assessment, Injury of liver | Altered Intercellular Communication | Importantly, neddylation inhibition, by using the pharmacological inhibitor, MLN4924, reduced liver injury, apoptosis, inflammation, and fibrosis by targeting different hepatic cell types. | 28035772 |
| Cessation of life, Inflammation, hepatic stellate cell activation | Altered Intercellular Communication | Under these circumstances, decreased hepatocyte cell death and inflammation after neddylation inhibition could partly account for reduction of hepatic stellate cell (HSC) activation. | 28035772 |
| Refractory anemias, Inflammation, Rheumatoid Arthritis | Altered Intercellular Communication | Recently, IL-34 was found to be associated with chronic inflammation, such as in rheumatoid arthritis (RA). | 28036035 |
| Kidney Failure, Chronic, Inflammation, Calcification of coronary artery, SLC25A20 gene, Cardiovascular Diseases, Cyclophosphamide/Vincristine/Dacarbazine Regimen | Altered Intercellular Communication | In end-stage renal disease (ESRD), coronary artery calcification (CAC) and inflammation contribute to cardiovascular disease (CVD). | 28036114 |
| Inflammation, SLC25A20 gene, Cyclophosphamide/Vincristine/Dacarbazine Regimen, Diabetes Mellitus | Altered Intercellular Communication | The association between CAC score and mortality remained significant after adjustment for age, gender, diabetes, CVD, use of statins, protein-energy wasting and inflammation. | 28036114 |
| Kidney Failure, Chronic, Inflammation, SLC25A20 gene | Altered Intercellular Communication | Elevated CAC score is a mortality risk factor in ESRD independent of inflammation. | 28036114 |
| Inflammation, Comorbidity | Altered Intercellular Communication | As the HIV-infected population ages, the role of cellular senescence and inflammation on co-morbid conditions and pharmacotherapy is increasingly of interest. | 28036343 |
| Inflammation | Altered Intercellular Communication | While inflammation is known to play a role in this population, it is not a major contributor to the p16INK4a association with decreased IM/EN exposures in these HIV-infected participants. | 28036343 |
| Inflammation, Primary malignant neoplasm | Altered Intercellular Communication | Serum or plasma proteases have been associated with various diseases including cancer, inflammation, or reno-cardiovascular diseases. | 28038565 |
| HD Term Type | Altered Intercellular Communication | Malnutrition-Inflammation-Atherosclerosis (MIA) factors significantly and independently affect life prognosis of hemodialysis (HD) patients. | 28038804 |
| Cystitis | Altered Intercellular Communication | The urinary tract inflammation rate (21%) was higher than that reported anecdotally. | 28038931 |
| Inflammation, Lung | Altered Intercellular Communication | The role of IL-17B in regulating pulmonary immunity and inflammation is unknown. | 28039016 |
| Inflammation, Lung, Pneumonia | Altered Intercellular Communication | In conclusion, human pneumonia was associated with enhanced release of IL-17B, which might regulate pulmonary immunity and inflammation through the induction of IL-8 in bronchial epithelial cells. | 28039016 |
| Granulomatosis, Systemic Vasculitis | Altered Intercellular Communication | Environmental factor and inflammation-driven alteration of the total peripheral T-cell compartment in granulomatosis with polyangiitis. | 28040323 |
| Autoimmune Diseases, Inflammation, Tissue damage | Altered Intercellular Communication | Autoimmune diseases are initiated by a combination of predisposing genetic and environmental factors resulting in self-perpetuating chronic inflammation and tissue damage. | 28040323 |
| Communicable Diseases, Inflammation, Cytomegalovirus | Altered Intercellular Communication | Altogether, on a genetic and cellular basis, here we show that alterations of the peripheral T-cell compartment are driven by inflammation and various environmental factors including concomitant CMV and EBV infection. | 28040323 |
| Inflammation, Nodular lesions | Altered Intercellular Communication | This patient had two 2-cm diameter chronic nodular lesions over the right mandible with no local inflammation and no other clinical findings of systemic disease. | 28040460 |
| Acute GVH disease | Altered Intercellular Communication | In multivariate analysis, growth hormone (GH) deficiency (hazard ratio [HR], 8.6; 95% confidence interval [CI], 2.1 to 34.4; P = .002), history of cranial radiation (HR, 4.0; 95% CI, 1.7 to 9.6; P = .002), and grade II-IV acute graft-versus-host disease GVHD (HR, 4.2; 95% CI, 1.5 to 12.2; P = .008) were associated with the risk of developing a CVRF cluster. | 28040534 |
| Inflammation | Altered Intercellular Communication | The monocyte to high-density lipoprotein ratio has recently emerged as an indicator of inflammation and oxidative stress. | 28040764 |
| Inflammatory Bowel Diseases, Inflammation | Altered Intercellular Communication | Plasma TWEAK levels do not reflect disease activity or the grade of inflammation in patients with newly diagnosed inflammatory bowel disease. | 28040992 |
| Hidradenitis Suppurativa, Inflammation | Altered Intercellular Communication | Biologics seem to offer a promising nonsurgical approach in hidradenitis suppurativa (HS), especially in disease with highly pronounced inflammation. | 28041632 |
| Renal Insufficiency, Atrial Fibrillation, Inflammation, Atrial Fibrillation by ECG Finding | Altered Intercellular Communication | D-dimer and vWF were significantly and positively associated with NT-proBNP (a marker of neurohormonal activation and left ventricular wall stress) even after adjustment for age, lifestyle characteristics, renal dysfunction, atrial fibrillation (AF) and inflammation (C-reactive protein). | 28043678 |
| Disruption, Trauma, Nervous System | Altered Intercellular Communication | We hypothesise that vascular disruption and concomitant release of monomeric-C-reactive protein within the brain tissue could exacerbate ongoing neurological damage via stimulation of neuro-inflammation and from direct consequences of its action on both neuronal and vascular cells. | 28044308 |
| Inflammation, Negative Regulation of Cell Cycle | Altered Intercellular Communication | Cellular senescence is characterized by a permanent cell-cycle arrest and a pro-inflammatory secretory phenotype, and can be induced by a variety of stimuli, including ionizing radiation, oxidative stress, and inflammation. | 28045034 |
| Inflammation, Thymus Hyperplasia | Altered Intercellular Communication | MG pathophysiology includes a strong component of inflammation, and a large proportion of patients with early onset MG additionally present thymus hyperplasia. | 28045063 |
| Communicable Diseases, Inflammation | Altered Intercellular Communication | Inflammaging is defined as low-grade, chronic, systemic inflammation in aging, in the absence of overt infection. | 28045067 |
| Communicable Diseases, Inflammation | Altered Intercellular Communication | Inflammaging is defined as low-grade, chronic, systemic inflammation in aging, in the absence of overt infection. | 28045067 |
| Inflammation | Altered Intercellular Communication | It was concluded that antigenic burdens encountered in intestine throughout life create the condition of chronic stage of inflammation, which accumulates M2-like macrophages expressing TNF-a. | 28045067 |
| Granulomatosis, Orofacial, Granulomatous inflammation, Swelling | Altered Intercellular Communication | Orofacial granulomatosis (OFG) is a controversial entity mainly characterised by recurrent or permanent soft tissue swelling of sudden onset in the orofacial area with a histologic appearance of granulomatous inflammation. | 28045322 |
| Granulomatous inflammation | Altered Intercellular Communication | A biopsy of the lower labial mucosa revealed granulomatous inflammation consistent with OFG. | 28045322 |
| Inflammation | Altered Intercellular Communication | Colonoscopy showed inflammation without clear evidence of CD. | 28045322 |
| Granulomatous inflammation, Swelling | Altered Intercellular Communication | The differential diagnosis in cases of orofacial swellings with histological granulomatous inflammation includes a variety of local and systemic diseases, diagnosis and management of which require full investigation and cooperation by a team of healthcare providers. | 28045322 |
| Inflammation, Lymphoma | Altered Intercellular Communication | This rare case of lymphoma in a patient with a history of foreign body injection indicated that practitioners must be aware that long-standing chronic inflammation resulting from dermal filler injections can trigger lymphoma development. | 28045813 |
| Airway structure, ARCN1 gene | Altered Intercellular Communication | Airway inflammation in COPD after long-term withdrawal of inhaled corticosteroids. | 28049170 |
| Airway structure, ARCN1 gene, Chronic Obstructive Airway Disease | Altered Intercellular Communication | Long-term treatment with inhaled corticosteroids (ICS) might attenuate lung function decline and decrease airway inflammation in a subset of patients with chronic obstructive pulmonary disease (COPD), and discontinuing ICS treatment could result in further lung function decline. | 28049170 |
| Airway structure, ARCN1 gene | Altered Intercellular Communication | The sputum total cell counts increased significantly in GL2 (1.90, 95% CI 1.42-2.54), as did counts of macrophages (2.10, 95% CI 1.55-2.86), neutrophils (1.92, 95% CI 1.39-2.65) and lymphocytes (2.01, 95% CI 1.46-2.78).ICS discontinuation increases airway inflammation in patients with moderate-severe COPD, suggesting that the anti-inflammatory effects of ICS in COPD are not maintained after ICS discontinuation. | 28049170 |
| Inflammation | Altered Intercellular Communication | Those who concurrently had PEW, inflammation, and CVD were a small proportion (0.4%). | 28049236 |
| Inflammation, Cholangiocarcinoma, Angiomyolipoma, Ovarian Cystadenocarcinoma, Bile duct adenoma, Cortical adenoma of kidney, Hepatoblastoma, Dysplastic nodule, Hemangioma, Malignant Neoplasms, Stage IV Nasopharyngeal Carcinoma, Lymphoepithelial carcinoma, Non-Neoplastic Disorder | Altered Intercellular Communication | Of the 18 patients, 7 patients (0.8%) were diagnosed with benign conditions (one each of hemangioma, inflammation, cortical adenoma, dysplastic nodule, angiomyolipoma, bile duct adenoma, and non-neoplastic liver parenchyme) and 11 patients (1.3%) were diagnosed with malignancies (cholangiocarcinoma [n = 6], hepatoblastoma [n = 2], and one each of lymphoepithelioma-like carcinoma, ovarian cystadenocarcinoma, and nasopharynx carcinoma metastasis). | 28049244 |
| Inflammation, Malnutrition, Diabetes Mellitus | Altered Intercellular Communication | This simple and readily available tool allows estimation of patient survival independently of other well-known key parameters such as age, gender, the presence of diabetes and markers of malnutrition and inflammation. | 28049587 |
| Inflammation, Neuropathology | Altered Intercellular Communication | Inflammation is targeted as responsible for the development of many neurologic pathologies. | 28050702 |
| Inflammation, Carcinoid Tumor | Altered Intercellular Communication | A better understanding of how inflammation induces cytological changes leading to development of a carcinoid from a cellular and molecular perspective could provide potential therapeutic strategies for preventing these lesions. | 28050998 |
| Inflammatory disease of mucous membrane | Altered Intercellular Communication | Lacrimal gland-derived IL-22 regulates IL-17-mediated ocular mucosal inflammation. | 28051088 |
| Inflammation, Ulcer | Altered Intercellular Communication | Barium esophagography, gastroesophageal endoscopy, and biopsy suggested esophageal-related chronic inflammation and ulcer, which probably caused the repeated esophagobronchial fistulas observed. | 28051197 |
| Inflammation, Chronic infectious disease, Atherosclerosis | Altered Intercellular Communication | To test if circulating levels of markers of inflammation, endothelial function, and chronic infections, as well as association between these markers and carotid intima media thickness (CIMT), depend on the stage of atherosclerosis expressed as a history of a major vascular event. | 28051279 |
| Inflammation, Carcinogenesis | Altered Intercellular Communication | Genetic variation in PPARGC1A may affect the role of diet-associated inflammation in colorectal carcinogenesis. | 28051997 |
| Inflammation, Carcinogenesis | Altered Intercellular Communication | The role of inflammation in colorectal carcinogenesis may differ according to individuals' genetic variations. | 28051997 |
| Inflammatory Bowel Diseases, Inflammation, Carcinogenesis | Altered Intercellular Communication | Inflammation is the driving force in inflammatory bowel disease (IBD) and its link to oxidative stress and carcinogenesis has long been accepted. | 28052094 |
| Inflammation | Altered Intercellular Communication | They might reduce Qmax rate and lead to reduction of the f/t PSA ratio and produce more severe inflammation causing increased seminal concentration of IL-1b and IL-8. | 28052296 |
| indurated, Scleroderma , Abnormal color | Altered Intercellular Communication | Morphoea (localized scleroderma) is a cutaneous inflammatory condition characterized by the development of indurated and discoloured plaques. | 28052367 |
| Liver carcinoma, Hepatitis, Chronic, Liver Cirrhosis, FAM126A gene | Altered Intercellular Communication | Most patients with a hepatocellular carcinoma (HCC) have an underlying chronic liver inflammation, which causes a continuous damage leading to liver cirrhosis and eventually HCC. | 28052383 |
| Inflammation, Neoplasms | Altered Intercellular Communication | CD8+ T cells that express retinoic acid-related orphan receptor (ROR)gt (TC17 cells) have been shown to promote procarcinogenic inflammation and contribute to a tolerogenic microenvironment in tumors. | 28053236 |
| Squamous cell carcinoma | Altered Intercellular Communication | Immunosuppression Induced by Chronic Inflammation and the Progression to Oral Squamous Cell Carcinoma. | 28053372 |
| Inflammation, SERPINB3 wt Allele | Altered Intercellular Communication | The results suggested that the immunosuppression induced by chronic inflammation promotes tumorigenesis in OSCC, rather than initiating it. | 28053372 |
| Degenerative polyarthritis, Inflammation | Altered Intercellular Communication | The aim of this study was to describe the histological features of erosive hand osteoarthritis (EHOA), which is considered an aggressive subset of hand osteoarthritis (OA) characterized by severe local inflammation and degeneration of the distal and proximal interphalangeal joints. | 28054155 |
| Liver carcinoma | Altered Intercellular Communication | Coenzyme Q10 and Oxidative Stress: Inflammation Status in Hepatocellular Carcinoma Patients after Surgery. | 28054958 |
| Inflammation, Hepatocarcinogenesis, FAM126A gene | Altered Intercellular Communication | The level of coenzyme Q10 was significantly positively correlated with antioxidant capacity (vitamin E and glutathione peroxidase activity) and negatively correlated with inflammation markers after surgery; (4) Conclusion: Hepatocarcinogenesis is associated with oxidative stress, and coenzyme Q10 may be considered an antioxidant therapy for patients with HCC, particularly those with higher inflammation after surgery. | 28054958 |
| Inflammation, Endophthalmitis, CTCAE, Panophthalmitis | Altered Intercellular Communication | Panophthalmitis is the most extensive ocular involvement in endophthalmitis with inflammation in periocular tissues. | 28056067 |
| Inflammation, Rupture, Scleral abscess, Perforation (observation), Corneal Opacity | Altered Intercellular Communication | Severe inflammation of the anterior and posterior segments is frequently accompanied by corneal opacity, scleral abscess, and perforation or rupture. | 28056067 |
| Autoimmune Chronic Hepatitis, Hepatitis, Liver Stiffness | Altered Intercellular Communication | Influence of Liver Inflammation on Liver Stiffness Measurement in Patients with Autoimmune Hepatitis Evaluation by Combinational Elastography. | 28056459 |
| Fibrosis Assessment, Hepatitis, Insemination, Artificial, Homologous | Altered Intercellular Communication | Combinational elastography was useful in evaluating not only the degree of liver fibrosis, but also the degree of liver inflammation in AIH. | 28056459 |
| Inflammation, Fibrosis Assessment, Idiopathic Pulmonary Fibrosis | Altered Intercellular Communication | Idiopathic pulmonary fibrosis (IPF) is characterized by the complex interaction of cells involved in chronic inflammation and fibrosis. | 28057004 |
| Renal Insufficiency, Inflammation, Nephrotoxic, Bacterial Endocarditis | Altered Intercellular Communication | Patients with infective endocarditis (IE) have an elevated risk of renal dysfunction because of extensive systemic inflammation and use of nephrotoxic antibiotics. | 28057030 |
| Inflammation, Vitamin B 12 Deficiency | Altered Intercellular Communication | Cobalamin deficiency was caused by asymptomatic chronic atrophic inflammation of the stomach with a lack of intrinsic factor producing gland cells. | 28057043 |
| Inflammation, Aneurysm | Altered Intercellular Communication | Hub protein of IKBKG in protein-protein interaction network was probably involved in the inflammation process in aneurysms. | 28057588 |
| Inflammation, Liver diseases | Altered Intercellular Communication | Oxidative stress and altered levels of different trace elements in serum have been documented for different diseases including inflammation and many liver diseases. | 28058664 |
| Inflammation, Chronic disease, Cardiovascular Diseases | Altered Intercellular Communication | Oxidative stress and inflammation are central to the development of a number of chronic diseases including cardiovascular disease and previous research suggests that blueberry consumption may attenuate these processes. | 28059417 |
| Temporomandibular Joint Disorders, Inflammation, Psychiatric, Chronic neck pain | Altered Intercellular Communication | Analysis of comorbidities revealed temporomandibular joint disorder, chronic cervical pain, depression/anxiety, and psychiatric medication use to be negatively associated with objective inflammation on CT or endoscopy. | 28059446 |
| Inflammation, Sinusitis, Headache Disorders, Primary | Altered Intercellular Communication | Given the high prevalence of sinusitis, improved clinical diagnostic criteria may assist primary care providers in more accurately predicting the presence of inflammation, thereby reducing inappropriate antibiotic use or delayed referral for evaluation of primary headache syndromes. | 28059446 |
| Pain Distress Question, Inflammation | Altered Intercellular Communication | None of the patients complained of worsening vision or pain after the intravitreal injections and no intraocular inflammation was seen. | 28060148 |
| Inflammation, Sternoclavicular joint structure, Hyperostosis | Altered Intercellular Communication | Further evaluation revealed hyperostosis of the sacroiliac joint and inflammation of the bilateral sternoclavicular joints and right sternocostal joint. | 28060551 |
| Inflammation, Necrosis | Altered Intercellular Communication | Abdominal computed tomography (10 days after admission) demonstrated a thickened pancreas in connection with inflammation and two small hypodense foci in the anterior part of the pancreas body, translating small foci of necrosis. | 28060696 |
| Chronic sclerosing sialadenitis | Altered Intercellular Communication | Chronic sclerosing sialadenitis is a benign inflammatory condition that most commonly affects the submandibular gland in elderly individuals. | 28060780 |
| Inflammation, Primary malignant neoplasm, Neoplasms | Altered Intercellular Communication | Tumor plasma contained a substantial tumor lysis signature, most prominent in Em-myc plasma, whereas Em-TCL1 plasma contained signatures of immune-response, inflammation and microenvironment interactions, with putative biomarkers in early-stage cancer. | 28062796 |
| Inflammation, Asthma | Altered Intercellular Communication | Inhaled corticosteroid dose response in asthma: Should we measure inflammation? | 28065396 |
| Airway structure | Altered Intercellular Communication | ICSs may not be increased on this basis despite residual airway inflammation. | 28065396 |
| Inflammation, Asthma | Altered Intercellular Communication | To compare the dose-response relationships of ICSs on measures of pulmonary function, symptoms, and inflammation in patients with persistent asthma. | 28065396 |
| Inflammation, AHR wt Allele | Altered Intercellular Communication | ICS dose response may extend beyond low dose for inflammation and AHR but not symptoms or spirometry. | 28065396 |
| Inflammation, Acute myocardial infarction, Reperfusion Injury | Altered Intercellular Communication | Inflammation is involved during acute myocardial infarction, and could be an interesting target to prevent ischaemia-reperfusion injuries. | 28065445 |
| Inflammation, Electrocardiogram: myocardial infarction (finding) | Altered Intercellular Communication | To evaluate the impact of colchicine on inflammation in patients admitted for ST-segment elevation myocardial infarction (STEMI). | 28065445 |
| Inflammation, Diabetes Mellitus, Non-Insulin-Dependent, Obesity | Altered Intercellular Communication | Inflammation is the most important link between obesity and type 2 diabetes (T2D). | 28067023 |
| Inflammation, Primary malignant neoplasm | Altered Intercellular Communication | Traditional Chinese herbal medicine (TCM) has been used in Chinese society for more than 5,000 years to treat diseases from inflammation to cancer. | 28067535 |
| NUMBL gene, Central neuroblastoma, Inflammation | Altered Intercellular Communication | The aim of this study was to analyze the prevalence of frailty and physical health limitations among long-term survivors of high-risk neuroblastoma (HR NBL) and to investigate whether frail health is associated with variables of cardiovascular function, markers of inflammation and telomere length. | 28067869 |
| Autoimmune Diseases, Inflammation, Prohepcidin, Refractory anemias | Altered Intercellular Communication | Prohepcidin positively correlated with the parameters of inflammation (CRP, ESR) and with the parameters for evaluation of autoimmune disorders (DAS 28 and RF) in the RA group. | 28068286 |
| Inflammation, Prohepcidin | Altered Intercellular Communication | The increase of both parameters provides information for tissue iron deficiency (assessed by the level of sTfR), caused by the inflammation when prohepcidin is expressed. | 28068286 |
| Hidradenitis Suppurativa, Inflammation, Chronic disease, Specimen Source Codes - Abscess | Altered Intercellular Communication | Hidradenitis suppurativa (HS) is a debilitating chronic disease that leads to inflammation and abscess formation in the involved skin, along with a malodorous discharge. | 28068657 |
| Symptoms, Inflammation, Exacerbation | Altered Intercellular Communication | This often leads to over-reliance on short-acting b2-agonist (SABA) reliever medication and under-treatment of the underlying inflammation, with poor control of asthma symptoms and increased risk of exacerbations. | 28069068 |
| Bacteremia, Inflammation | Altered Intercellular Communication | Transient bacteraemia, following urinary catheterisation, with seeding of existing sites of inflammation is the proposed explanation. | 28069785 |
| Inflammation, Phenylketonurias | Altered Intercellular Communication | Phenylketonuria is not a risk factor for changes of inflammation status as assessed by interleukin 6 and interleukin 8 concentrations. | 28071012 |
| Inflammation, Phenylketonurias | Altered Intercellular Communication | High oxidative stress and a reduced potential for free radical scavenging in phenylketonuria (PKU) patients, a phenomenon confirmed in a few studies, may lead to systemic chronic inflammation. | 28071012 |
| Inflammation, Phenylketonurias | Altered Intercellular Communication | Phenylketonuria is not a risk factor for changes of inflammation status as assessed by IL-6 and IL-8 concentrations. | 28071012 |
| Inflammation, Metabolic Syndrome X | Altered Intercellular Communication | Chemerin levels are significantly linked to inflammation and metabolic syndrome. | 28071854 |
| Inflammation, Adenocarcinoma Of Esophagus | Altered Intercellular Communication | Preoperative markers of systemic inflammation predict poor outcome in patients undergoing curative treatment for locally advanced oesophageal and gastro-oesophageal adenocarcinoma. | 28072456 |
| Inflammation | Altered Intercellular Communication | Inflammation is a key factor contributing to alterations in aerobic capacity, and interleukin (IL)-1 cytokines are implicated in this process. | 28072632 |
| Leydig Cell Tumor, Inflammation, Neoplasms, Fibrosis Assessment, Sertoli Cell Tumor, Angiofibroma, Malignant Neoplasms, Tubular atrophy, Seminoma, Adenomatoid Tumor | Altered Intercellular Communication | Definitive pathological results were: malignant tumor in 6 cases (seminoma), benign tumor in 10 cases (5 Leydig tumors, 2 Sertoli tumors, 1 epidermoid cyst, 1 adenomatoid tumor, 1 angiofibroma), benign disease in 11 (8 inflammation with haemorragic infiltration, 2 tubular atrophy, 1 fibrosis), and normal parenchyma in 1 case. | 28073203 |
| Inflammation, Primary malignant neoplasm, Patient Satisfaction with Cancer Care Questionnaire | Altered Intercellular Communication | However, altered gene expression in PSCC affects canonical pathways and cellular and biological processes, such as inflammation and DNA damage response, which are highly consistent with hallmarks of cancer. | 28073359 |
| Airway structure, Progranulins, Asthma | Altered Intercellular Communication | Serum progranulin as an indicator of neutrophilic airway inflammation and asthma severity. | 28073702 |
| Inflammation, Progranulins | Altered Intercellular Communication | Progranulin, a protein secreted from the airway epithelium, is known to attenuate the downstream cascade of neutrophilic inflammation in particular. | 28073702 |
| Refractory anemias, Rheumatoid Arthritis, Electrocardiogram: myocardial infarction (finding), Inflammation | Altered Intercellular Communication | Patients with rheumatoid arthritis (RA) are at increased risk of myocardial infarction (MI) compared with subjects without RA, with the increased risk driven potentially by inflammation. | 28073800 |
| Inflammation, Gastrointestinal Diseases | Altered Intercellular Communication | More recently, it has been shown that H. pylori cytotoxin CagA expression induces cellular senescence of human gastric nonpolarized epithelial cells that may lead to gastrointestinal disorders and systemic inflammation. | 28074309 |
| Inflammation | Altered Intercellular Communication | The manifestations of the present case suggest that a systemic inflammation might occur in the unicentric form of the disease possibly due to cytokine hypersecretion. | 28074445 |
| Inflammation, Angiolymphoid hyperplasia | Altered Intercellular Communication | Unicentric disease is a surgical condition and warrants a follow-up based on the systemic inflammation that might occur. | 28074445 |
| Helicobacter cinaedi, atherosclerotic | Altered Intercellular Communication | The Helicobacter cinaedi antigen CAIP participates in atherosclerotic inflammation by promoting the differentiation of macrophages in foam cells. | 28074932 |
| Coinfection, Inflammation, Atherosclerosis | Altered Intercellular Communication | Recent studies have shown that certain specific microbial infections participate in atherosclerosis by inducing inflammation and immune reactions, but how the pathogens implicated in this pathology trigger the host responses remains unknown. | 28074932 |
| Inflammation, atherosclerotic, Atherosclerosis | Altered Intercellular Communication | CAIP appears to be implicated in this pathology because atheromatous plaques isolated from atherosclerotic patients are enriched in CAIP-specific T cells (10%) which, in turn, we show to drive a Th1 inflammation, an immunopathological response typically associated to atherosclerosis. | 28074932 |
| Communicable Diseases, Atherosclerosis | Altered Intercellular Communication | This study identifies CAIP as a relevant factor in atherosclerosis inflammation linked to Hc infection and suggests that preventing and eradicating Hc infection could reduce the incidence of atherosclerosis. | 28074932 |
| Inflammation, Fibrosis Assessment, Liver Stiffness | Altered Intercellular Communication | Coffee consumption decreases liver stiffness, which may indicate less fibrosis and inflammation, independent of disease state. | 28075394 |
| Inflammation, Prostate carcinoma | Altered Intercellular Communication | Inflammation, cardiometabolic markers, and functional changes in men with prostate cancer. | 28075422 |
| Communicable Diseases, Inflammation | Altered Intercellular Communication | We studied their association with inflammation (C-reactive protein), infection (procalcitonin) and clinical outcome. | 28076309 |
| Sepsis, Communicable Diseases, Inflammation | Altered Intercellular Communication | IDO and kynurenine showed a strong positive correlation with markers of infection (procalcitonin) and inflammation (C-reactive protein) as well as sepsis and CAP severity scores. | 28076309 |
| Neoplasms | Altered Intercellular Communication | The predictive performance of AGR was compared with other inflammation-based scores and serological tumor markers in terms of concordance index (C-index). | 28076328 |
| Neoplasms | Altered Intercellular Communication | The C-index of AGR was superior to other inflammation-based scores and serological tumor markers in OS and RFS prediction. | 28076328 |
| Metastatic urothelial carcinoma | Altered Intercellular Communication | Novel Inflammation-Based Prognostic Score for Predicting Survival in Patients with Metastatic Urothelial Carcinoma. | 28076369 |
| Nail-Patella Syndrome, Carcinoma, Transitional Cell, Ulcerative Colitis | Altered Intercellular Communication | We developed a novel inflammation-based model (NPS), which consisted of a neutrophil to lymphocyte ratio (NLR) and platelet count (PC), for assessing the prognostic role in patients with metastatic urothelial carcinoma (UC). | 28076369 |
| Communicable Diseases, Arthritis, Inflammation | Altered Intercellular Communication | During active infection, miRNA expression in SF reflected an immune response associated with bacterial killing, while in postinfectious LA, miRNA expression in SF and synovial tissue reflected chronic inflammation, synovial proliferation, and breakdown of wound repair processes, showing that the nature of the arthritis was altered after spirochetal killing. | 28076897 |
| Inflammation, Coronary heart disease, Choline Dehydrogenase, Mitochondrial | Altered Intercellular Communication | With such combined changes in lipids, lipid sub-fractions, and inflammation, which are considered among the most effective means of reducing coronary heart disease (CHD), this PMILLS represents a new addition to safe and effective lipid-modifying strategies. | 28078862 |
| Inflammation, AATF wt Allele, Dry Eye Syndromes | Altered Intercellular Communication | Lifitegrast is a lymphocyte function-associated antigen-1 antagonist developed to reduce inflammation in dry eye disease (DED). | 28079022 |
| Inflammation | Altered Intercellular Communication | TRIM22 is constitutively expressed at high levels in monocytes and plays important roles in the antiviral response and inflammation. | 28079123 |
| Inflammation, Pleural effusion disorder | Altered Intercellular Communication | Exudative pleural effusions may arise secondary to inflammation of intra-abdominal structures. | 28079399 |
| Inflammation, Hyperplasia, Internal, Cyst | Altered Intercellular Communication | CBA cysts typically lacked epithelium and inflammation; cyst walls had an inner, dense cicatricial layer associated with myofibroblastic (MF) hyperplasia that often delaminated producing a grossly visible inner cyst wall. | 28079575 |
| Inflammation, Observation Method - Coagulation, Hypoxia, Septic Shock | Altered Intercellular Communication | In patients with septic shock, alterations in inflammation, coagulation, oxidative stress, and tissue hypoxia are common and associated with adverse outcomes but are not influenced by protocol-based resuscitation compared with usual care. | 28079606 |
| Gastric mucosa | Altered Intercellular Communication | To investigate the value of quantitative analysis in dual energy spectral computed tomography (DESCT) for differentiating malignant gastric mucosal lesions from benign gastric mucosal lesions (including gastric inflammation [GI] and normal gastric mucosa [NGM]). | 28079827 |
| Inflammation | Altered Intercellular Communication | In BD patients, choroidal thickness decreased over time, which was associated with length of active inflammation. | 28080153 |
| Intraocular inflammation | Altered Intercellular Communication | It suggests intraocular inflammation in BD affects the choroid as well as the retina. | 28080153 |
| Inflammation, Hepatitis | Altered Intercellular Communication | A liver biopsy demonstrated portal inflammation and hepatitis with apoptotic hepatocytes. | 28081586 |
| Autoimmune Diseases, Lichen Sclerosus et Atrophicus, Infection, Traumatic injury | Altered Intercellular Communication | Several factors such as genetic susceptibility, autoimmunity, hormones, infections, local trauma, urine, and occlusion have been speculated to play a role in the pathogenesis of lichen sclerosus. | 28081682 |
| Abnormal renal function, Inflammation, Electrocardiogram: myocardial infarction (finding) | Altered Intercellular Communication | Kidney dysfunction, systemic inflammation and mental well-being in elderly post-myocardial infarction patients. | 28081723 |
| Abnormal renal function, Inflammation, Electrocardiogram: myocardial infarction (finding) | Altered Intercellular Communication | The aim was to investigate whether mild kidney dysfunction and low-grade inflammation in post-myocardial infarction patients are independently associated with markers of mental well-being (i.e. | 28081723 |
| Inflammation, Electrocardiogram: myocardial infarction (finding), Bipolar Disorder, Renal function, Apathy | Altered Intercellular Communication | In post-myocardial infarction patients, impaired kidney function and systemic inflammation showed a stronger association with apathy than with depressive symptoms and dispositional optimism. | 28081723 |
| Pneumonitis | Altered Intercellular Communication | Previously, we described that protein arginine methyltransferase 1 (PRMT1) participates in airway remodeling in pulmonary inflammation in E3 rats. | 28081849 |
| Inflammation, Myocardial, CEL gene | Altered Intercellular Communication | A greater decline of circulating FAP concentrations in the first 5days after STEMI is associated with increased myocardial damage and inflammation. | 28082091 |
| Atrial Fibrillation, Inflammation, Atrial Fibrillation by ECG Finding | Altered Intercellular Communication | Right ventricular (RV) morphology has been associated with drivers of atrial fibrillation (AF) risk, including left ventricular and pulmonary pathology, systemic inflammation, and neurohormonal activation. | 28082528 |
| Inflammation, Vitreous humor, Diabetic Retinopathy | Altered Intercellular Communication | Inflammation and N-formyl peptide receptors mediate the angiogenic activity of human vitreous humour in proliferative diabetic retinopathy. | 28083635 |
| Inflammation, PDR gene, Diabetic Retinopathy, Diabetes Mellitus | Altered Intercellular Communication | Angiogenesis and inflammation characterise proliferative diabetic retinopathy (PDR), a major complication of diabetes mellitus. | 28083635 |
| Inflammation, Pathologic Neovascularization | Altered Intercellular Communication | However, the impact of inflammation on the pathogenesis of PDR neovascularisation has not been elucidated. | 28083635 |
| Tinea profunda (disorder), Granulomatous inflammation, Arthrodermataceae | Altered Intercellular Communication | Majocchi's granuloma is an intracutaneous or subcutaneous granulomatous inflammation caused by invasion of dermatophytic fungus, especially Trichophyton rubrum. | 28083794 |
| Inflammation, Sleep Apnea, Obstructive | Altered Intercellular Communication | Shorter telomere length and obstructive sleep apnea are associated with increased oxidative stress and chronic inflammation, which are both considered leading causes of age-related diseases. | 28083855 |
| Hematoma, Swelling | Altered Intercellular Communication | Noninfectious prevertebral soft-tissue inflammation and hematoma eliciting swelling after anterior cervical discectomy and fusion. | 28084931 |
| Communicable Diseases, Inflammation, Esophageal Perforation | Altered Intercellular Communication | When it coincides with prevertebral space enlargement and inflammation, surgical site infection and pharyngoesophageal perforation must be considered. | 28084931 |
| Deglutition Disorders, Spondylitis | Altered Intercellular Communication | The association between dysphagia and prevertebral inflammation has not been reported. | 28084931 |
| Deglutition Disorders, Spondylitis | Altered Intercellular Communication | The authors investigated factors eliciting severe dysphagia and its relationship with prevertebral inflammation in patients who had undergone ACDF. | 28084931 |
| Inflammation, Hematoma, teratologic | Altered Intercellular Communication | In other cases these anomalies are elicited by hematoma not associated with inflammation. | 28084931 |
| Metabolic Diseases, Keratoconus | Altered Intercellular Communication | Therefore, metabolic disorder and hormonal balance may both have an impact on keratoconus development. | 28085502 |
| Inflammation, Biliary calculi | Altered Intercellular Communication | Acute acalculous cholecystitis (AAC) is an inflammation of the gallbladder without the presence of gallstones. | 28085529 |
| Neurodegenerative Disorders, Inflammation, Brain Injuries | Altered Intercellular Communication | Increased expression of translocator protein (TSPO) has been observed after brain injury and inflammation in neurodegenerative diseases. | 28086916 |
| Inflammation, Rheumatoid Arthritis, Physical disability, Synovitis | Altered Intercellular Communication | The relationship between synovitis quantified by an ultrasound 7-joint inflammation score and physical disability in rheumatoid arthritis - a cohort study. | 28086960 |
| Inflammation | Altered Intercellular Communication | It is unknown, whether the extent of synovial inflammation quantified by musculoskeletal ultrasound (US) can predict current or future capacity for physical functioning. | 28086960 |
| Inflammation, Hemorrhage, Electrocardiogram: myocardial infarction (finding), Coronary Arteriosclerosis, Myocarditis, CTCAE 5.0 | Altered Intercellular Communication | Lymphocytic myocarditis occurs with myocardial infarction and coincides with increased inflammation, hemorrhage and instability in coronary artery atherosclerotic plaques. | 28087177 |
| Inflammation, Dental Plaque, Coronary Artery Vasospasm, atherosclerotic | Altered Intercellular Communication | Moreover, LM was associated with remodeling and inflammation of atherosclerotic plaques indicative of plaque destabilization pointing to coronary spasm, suggesting that preexistent LM, or its causes, may facilitate the development of MI. | 28087177 |
| Inflammation, Vesicoureteral Reflux 1, Hydronephrosis, Renal scarring | Altered Intercellular Communication | The following clinical variables were compared: age at diagnosis of primary VUR (months), sex, VUR grade, hydronephrosis grade, presence of renal scarring, surgical treatment, and degree of inflammation during fUTI. | 28087230 |
| Autoimmune Diseases, Acute and chronic inflammation | Altered Intercellular Communication | Populations of CD4+CD28null T cells, with apparently contradictory physiological roles, have recently been reported, along with the co-expression of the NK activating receptor NKG2D, in autoimmune diseases and chronic viral inflammation. | 28087292 |
| septic | Altered Intercellular Communication | Thioredoxin (TRX), an endogenous anti-oxidant protein induced in inflammatory conditions, has been shown to increase in plasma and to be associated with outcome in septic patients. | 28087409 |
| Celiac Disease, Gastrointestinal inflammation | Altered Intercellular Communication | While the pathophysiological link between the oral and gut microbiomes in CD needs further exploration, the presented data suggest that oral microbe-derived enzyme activities are elevated in subjects with CD, which may impact gluten processing and the presentation of immunogenic gluten epitopes to the immune system in the small intestine.IMPORTANCE Ingested gluten proteins are the triggers of intestinal inflammation in celiac disease (CD). | 28087531 |
| Inflammation, Impaired cognition, "Alzheimers Disease | Altered Intercellular Communication | Iso-a-acids, Bitter Components of Beer, Prevent Inflammation and Cognitive Decline Induced in a Mouse Model of Alzheimer's Disease. | 28087694 |
| Inflammation | Altered Intercellular Communication | Here we found that iso-a-acids, hop-derived bitter compounds in beer, enhance microglial phagocytosis and suppress inflammation via activation of the peroxisome proliferator-activated receptor g. In normal mice, oral administration of iso-a-acids led to a significant increase both in CD11b and CD206 double-positive anti-inflammatory type microglia (p < 0.05) and in microglial phagocytosis in the brain. | 28087694 |
| Inflammation, "Alzheimers Disease | Altered Intercellular Communication | The present study is the first to report that amyloid b deposition and inflammation are suppressed in a mouse model of Alzheimer's disease by a single component, iso-a-acids, via the regulation of microglial activation. | 28087694 |
| Granuloma, Inflammation, Crohn Disease | Altered Intercellular Communication | Association of granulomas in mesenteric lymph nodes in Crohn's disease with younger age and transmural inflammation. | 28087973 |
| Granuloma, Inflammation, Abscess, Fibrosis Assessment, Hypertrophy, Intestines, Small | Altered Intercellular Communication | The presence of MLN granuloma was associated with mural granuloma, transmural inflammation, mural abscess, hypertrophy of the muscularis propria, fibrosis of the muscularis propria, and serosal fibrosis in the small bowel. | 28087973 |
| Granuloma, Inflammation | Altered Intercellular Communication | The multivariable analysis confirms that MLN granuloma was associated with age and transmural inflammation. | 28087973 |
| Granuloma, Inflammation | Altered Intercellular Communication | In CD patients who underwent the index ICR, the presence of MLN granuloma was associated with younger age and transmural inflammation. | 28087973 |
| Granuloma, Inflammation | Altered Intercellular Communication | Our current results suggest that the detection of MLN granulomas may be enhanced in patients at higher risk, that is, younger patients or those with transmural inflammation on imaging or histopathology. | 28087973 |
| Inflammation | Altered Intercellular Communication | However, the effect of SCE on inflammation in animals is still obscure. | 28088324 |
| Colitis | Altered Intercellular Communication | Mice in DSS and DSS+SCE groups were also given a 4% DSS solution from 7-week to 8-week-old via drinking water to induce colonic inflammation. | 28088324 |
| Damage, physiopathological, Colitis | Altered Intercellular Communication | The results showed that dietary SCE alleviated DSS induced growth suppression, splenic damage, colonic histological changes, colonic inflammation, oxidative stress, and colonic dysfunction of tight junctions. | 28088324 |
| Inflammation | Altered Intercellular Communication | In conclusion, SCE conferred a protective role in the DSS-induced inflammation and the mechanism might be associated with the activated signals of the nuclear factor kappa B p65 and Nrf2. | 28088324 |
| Inflammation, Cardiovascular Diseases | Altered Intercellular Communication | Amygdalar activity was associated with increased bone-marrow activity (r=0*47; p<0*0001), arterial inflammation (r=0*49; p<0*0001), and risk of cardiovascular disease events (standardised hazard ratio 1*59, 95% CI 1*27-1*98; p<0*0001), a finding that remained significant after multivariate adjustments. | 28088338 |
| Inflammation, Cardiovascular Diseases | Altered Intercellular Communication | The association between amygdalar activity and cardiovascular disease events seemed to be mediated by increased bone-marrow activity and arterial inflammation in series. | 28088338 |
| Arteritis | Altered Intercellular Communication | In the separate cross-sectional study of patients who underwent psychometric analysis (n=13), amygdalar activity was significantly associated with arterial inflammation (r=0*70; p=0*0083). | 28088338 |
| Inflammation | Altered Intercellular Communication | Perceived stress was associated with amygdalar activity (r=0*56; p=0*0485), arterial inflammation (r=0*59; p=0*0345), and C-reactive protein (r=0*83; p=0*0210). | 28088338 |
| Inflammation, Traumatic injury | Altered Intercellular Communication | Increased understanding of factors associated with inflammation after trauma and PRBC transfusion is needed. | 28088436 |
| Chronic prostatitis, prostatitis | Altered Intercellular Communication | Chronic Prostate Inflammation Predicts Symptom Progression in Patients with Chronic Prostatitis/Chronic Pelvic Pain. | 28089730 |
| prostatitis | Altered Intercellular Communication | We examined the 4-year longitudinal association between histological prostate inflammation and chronic prostatitis/chronic pelvic pain syndrome. | 28089730 |
| Inflammation, Pain Distress Question | Altered Intercellular Communication | At multiple time points during 4 years univariable and multivariable analyses were performed between acute and chronic inflammation detected on baseline biopsies and the incidence of chronic pelvic pain syndrome-like symptoms, defined as a positive response to CPSI (Chronic Prostatitis Symptom Index) question 1a-perineal pain and/or question 2b-ejaculatory pain and a total pain subscore of at least 4, and progression of chronic prostatitis/chronic pelvic pain syndrome, defined as a 4-point or greater increase from baseline in total CPSI score, in patients with a baseline categorization of chronic prostatitis/chronic pelvic pain syndrome. | 28089730 |
| Inflammation | Altered Intercellular Communication | Of the 4,109 men in the study acute and chronic inflammation was detected in 641 (15.6%) and 3,216 (78.3%), respectively. | 28089730 |
| Inflammation | Altered Intercellular Communication | Acute and chronic inflammation was not associated with the incidence of the symptoms (p >0.1). | 28089730 |
| Inflammation | Altered Intercellular Communication | Chronic but not acute inflammation was significantly associated with shorter time to progression on univariable and multivariable analyses (p = 0.029 and 0.018, respectively). | 28089730 |
| Inflammation | Altered Intercellular Communication | Inflammation is not associated with an increased risk of chronic prostatitis/chronic pelvic pain syndrome. | 28089730 |
| Inflammation | Altered Intercellular Communication | However, chronic inflammation predicts the risk of symptomatic progression in men in whom chronic prostatitis/chronic pelvic pain syndrome symptoms have been identified. | 28089730 |
| Inflammation, Primary malignant neoplasm, Carcinogenesis | Altered Intercellular Communication | Network analysis of known and putative mRNA targets of these miRs was enriched with cancer and inflammation pathways, consistent with known roles of stroma and of vitamin D in carcinogenesis. | 28089917 |
| Myocarditis, CTCAE 5.0, Myocarditis | Altered Intercellular Communication | Eosinophilic myocarditis is a rare form of myocardial inflammation that is characterized by the infiltration of eosinophilic cells into the myocardium. | 28090045 |
| Inflammation, Primary malignant neoplasm | Altered Intercellular Communication | Impact of celecoxib on inflammation during cancer surgery: a randomized clinical trial. | 28092065 |
| Inflammation, Primary malignant neoplasm, Neoplasm Metastasis | Altered Intercellular Communication | During cancer surgery, prostaglandin-mediated inflammation may promote and activate micrometastatic disease with a consequent increase in long-term cancer recurrence. | 28092065 |
| Inflammation, Obesity | Altered Intercellular Communication | High-sensitivity C-reactive protein is increased and negatively associated with anti-oxidation in pre-pubertal obese boys, suggesting that childhood obesity is associated with aseptic inflammation and oxidative stress. | 28092067 |
| Inflammation | Altered Intercellular Communication | Low-grade, chronic inflammation has been associated with many diseases of aging, but the mechanisms responsible for producing this inflammation remain unclear. | 28092664 |
| Communicable Diseases, Inflammation | Altered Intercellular Communication | Inflammasomes can drive chronic inflammation in the context of an infectious disease or cellular stress, and they trigger the maturation of interleukin-1b (IL-1b). | 28092664 |
| Inflammation | Altered Intercellular Communication | Thus, targeting inflammasome components may ameliorate chronic inflammation and various other age-associated conditions. | 28092664 |
| Inflammation, Disease | Altered Intercellular Communication | Whilst C-reactive protein (CRP) is an established serum marker of inflammation, its use in gastroenterology has been limited by its poor sensitivity and specificity for GI disease. | 28093196 |
| Gastrointestinal inflammation | Altered Intercellular Communication | Faecal calprotectin (FC) has been adopted into mainstream GI practice as a sensitive but non-specific marker of intestinal inflammation. | 28093196 |
| Gastrointestinal inflammation | Altered Intercellular Communication | Therefore, as a serum biomarker for intestinal inflammation, SC is unlikely to be of clinical utility and the search for an appropriate serum GI biomarker continues. | 28093196 |
| Unresectable, Weight decreased, Inflammation | Altered Intercellular Communication | Eligible patients for the double-blind phase of this ongoing, placebo-controlled, randomised, phase 3 trial, had metastatic or unresectable disease, Eastern Cooperative Oncology Group performance status score 1 or 2, systemic inflammation, weight loss, and other disease-related morbidities associated with poor prognosis, and were refractory to oxaliplatin and irinotecan. | 28094194 |
| methyldopa, Inflammation | Altered Intercellular Communication | There is evidence that nutrition, inflammation and genetic risk factors play an important role in the development of AMD. | 28094305 |
| Inflammation, Metabolic Diseases | Altered Intercellular Communication | Recent studies suggest that the composition of the intestinal microbiome is associated with metabolic diseases through modulation of inflammation and host metabolism. | 28094305 |
| Inflammation, musculoskeletal regeneration | Altered Intercellular Communication | Overall this work demonstrates a novel method for modulating cell response to inflammatory signaling that has applications in engineering cells delivered to inflammatory environments, and as a direct gene therapy to protect endogenous cells exposed to chronic inflammation, as observed in a broad spectrum of degenerative musculoskeletal pathology. | 28095751 |
| Inflammation, musculoskeletal regeneration | Altered Intercellular Communication | Overall this work demonstrates a novel method for modulating cell response to inflammatory signaling that has applications in engineering cells delivered to inflammatory environments, and as a direct gene therapy to protect endogenous cells exposed to chronic inflammation, as observed in a broad spectrum of degenerative musculoskeletal pathology. | 28095751 |
| Inflammation Mediators | Altered Intercellular Communication | Here we show that microenvironmental cues, including inflammation-mediated resistance to adoptive T-cell immunotherapy, transcriptionally repress MITF via ATF4 in response to inhibition of translation initiation factor eIF2B. | 28096186 |
| Malignant Neoplasms | Altered Intercellular Communication | Of the 181 cases, histopathology was positive for malignancy in 166 (92%) patients and showed benign inflammation/fibrosis in 15 (8%) patients. | 28097388 |
| Hormone abnormality, Hypertrophy | Altered Intercellular Communication | Due to non-specific hormonal disorders and enlargement of the lesion, a right-sided laparoscopic adrenalectomy was performed. | 28097642 |
| Proteinuria, Inflammation, Chronic Kidney Diseases | Altered Intercellular Communication | The relationship between mean platelet volume and neutrophil/lymphocyte ratio with inflammation and proteinuria in chronic kidney disease. | 28098108 |
| Inflammation, Chronic Kidney Diseases, Atherosclerosis | Altered Intercellular Communication | Atherosclerosis, which develops as a result of inflammation, is the most important cause of morbidity and mortality in chronic kidney disease (CKD). | 28098108 |
| Proteinuria, Inflammation, Chronic Kidney Diseases | Altered Intercellular Communication | In this study, we investigated the relationship of mean platelet volume (MPV) and neutrophil/lymphocyte ratio (NLR) with inflammation and proteinuria in patients with CKD Stage 3-4. | 28098108 |
| Inflammation, Chronic Kidney Diseases, Atherosclerosis | Altered Intercellular Communication | NLR may be a determinant of inflammation and atherosclerosis in patients with CKD. | 28098108 |
| Necrosis, Necrotizing granulomatous inflammation, Abscess, Suppuration, Hyperplasia | Altered Intercellular Communication | The histopathology in immunocompetent patients was characterized by pseudoepitheliomatous epidermal hyperplasia, intraepithelial abscesses, transepidermal elimination and dermal granulomatous inflammation accompanied by necrosis and suppuration. | 28098393 |
| Inflammation, Immunocompromised Host, Granuloma | Altered Intercellular Communication | The immunocompromised patients showed suppurative inflammation with little granuloma formation and numerous acid-fast bacilli. | 28098393 |
| Jaundice, Obstructive | Altered Intercellular Communication | Prognostic value of inflammation-based markers in patients with recurrent malignant obstructive jaundice treated by reimplantation of biliary metal stents: A retrospective observational study. | 28099348 |
| Inflammation, Communicable Diseases, Injury of lens, Hyphema, Hypopyon | Altered Intercellular Communication | No serious complications such as infection, hyphema, lens trauma or severe inflammation including hypopyon and AC fibrin formation were observed. | 28100481 |
| Inflammation, Necrosis | Altered Intercellular Communication | The IPA suggested that increased inflammation, immune activation with decreased necrosis and apoptosis preceded poor outcome. | 28100627 |
| Inflammation | Altered Intercellular Communication | BACKGROUND Increasing evidence suggests that cancer-associated inflammation is associated with poorer outcomes. | 28100902 |
| Inflammation, Colorectal Carcinoma | Altered Intercellular Communication | The neutrophil-to-lymphocyte ratio (NLR), considered as a systemic inflammation marker, is thought to predict prognoses in colorectal cancer. | 28100902 |
| Congenital pericardial cyst, Inflammation, Rupture, Chest Pain | Altered Intercellular Communication | Inflammation and Rupture of a Congenital Pericardial Cyst Manifesting Itself as an Acute Chest Pain Syndrome. | 28100978 |
| Congenital pericardial cyst, Inflammation, Chest Pain, Rupture | Altered Intercellular Communication | The suspected cause of the patient's chest pain was acute inflammation of a congenital pericardial cyst with subsequent rupture and resolution of symptoms. | 28100978 |
| Inflammation | Altered Intercellular Communication | Inflammation seems to be associated with the presence of a specific clinical subtype in PDLRRK2 that is characterized by a broad and more severely affected spectrum of motor and non-motor symptoms. | 28102045 |
| Amyotrophic Lateral Sclerosis, Inflammation | Altered Intercellular Communication | Hence, given the role of inflammation in the development of ALS, the high translational impact of the model, the known anti-inflammatory properties of these extracts, and the viability of their clinical use, these results suggest that the application of Wse and Mpe might represent a valuable pharmacological strategy to counteract the progression of ALS and related symptoms. | 28102336 |
| Inflammation | Altered Intercellular Communication | The pathological findings confirmed diverticulum penetration into the mesentery and severe inflammation at the site, with surrounding ectopic pancreas. | 28102481 |
| Diabetes Mellitus, Insulin-Dependent, Inflammation, Endothelial dysfunction | Altered Intercellular Communication | Cardiovascular risk in type 1 diabetes mellitus (T1DM) is associated with endothelial dysfunction, inflammation, and altered immunity. | 28102614 |
| Inflammation, Weight decreased | Altered Intercellular Communication | Systemic inflammation is suggested to be associated with weight loss. | 28102709 |
| Inflammation, Pre-Eclampsia | Altered Intercellular Communication | South African (SA) Black women have a high prevalence of preeclampsia and HIV, both conditions associated with increased inflammation. | 28103790 |
| Inflammation, Electrocardiogram: myocardial infarction (finding), Obesity, Visceral | Altered Intercellular Communication | Relationship key factor of inflammation and the development of complications in the late period of myocardial infarction in patients with visceral obesity. | 28103807 |
| Inflammation, Pulmonary Emphysema | Altered Intercellular Communication | These data suggest that type VI collagen turnover and elastin degradation by neutrophil elastase are associated with COPD-induced inflammation (eosinophil-bronchitis) and emphysema. | 28103932 |
| Necrotizing granulomatous inflammation, Aspergillus, Fungal | Altered Intercellular Communication | Biopsy of the transplanted kidney showed severe necrotizing granulomatous inflammation and fungal elements consistent with aspergillus species. | 28104135 |
| Autoimmune Diseases, Inflammation, Axonal degeneration | Altered Intercellular Communication | Multiple sclerosis (MS) is an autoimmune disease characterized by inflammation and axonal degeneration of the central nervous system and a leading cause of disability in young adults. | 28104261 |
| Celiac Disease, Have Autoimmune or Inflammatory Condition, Lymphoma, Gastrointestinal Stromal Sarcoma | Altered Intercellular Communication | Celiac disease (CD), an autoimmune inflammation of small intestine, has increasing prevalence in the elderly and may lead to lymphomas and gastrointestinal malignancies. | 28104447 |
| Inflammation | Altered Intercellular Communication | Participants had some natural teeth, periodontal inflammation, non-aggressive behaviour, no communicable diseases, were non-smokers and non-comatose. | 28105737 |
| Inflammation, Hemorrhage, Dental Plaque | Altered Intercellular Communication | Outcomes were measured at baseline and 6 weeks, which included: inflammation (MGI, Lobene), bleeding (PBI, Loesche) and Plaque (Turesky). | 28105737 |
| Inflammation, Pneumonia | Altered Intercellular Communication | 25-Hydroxy-Vitamin D Concentration Is Not Affected by Severe or Non-Severe Pneumonia, or Inflammation, in Young Children. | 28106720 |
| Communicable Diseases, Inflammation | Altered Intercellular Communication | Infection and inflammation did not alter the 25(OH)D concentration in young children with acute lower respiratory tract infections. | 28106720 |
| Refractory anemias, Rheumatoid Arthritis, Arthritis, Autoimmune Diseases | Altered Intercellular Communication | Rheumatoid Arthritis (RA) is a progressive autoimmune disease characterized by chronic joint inflammation and structural damage. | 28107378 |
| Crohn Disease, Inflammatory disease of mucous membrane | Altered Intercellular Communication | Crohn's disease (CD) is a chronic mucosal inflammation that affects the intestinal barrier function, for example, by altering the intestinal permeability. | 28107568 |
| Inflammatory disease of mucous membrane | Altered Intercellular Communication | OHIG and EEN resulted in virtually similar reductions in the signs and symptoms of mucosal inflammation. | 28107568 |
| Inflammation, Intratumoral | Altered Intercellular Communication | GKRS-induced complications (intratumoral bleeding and tumoral tissue inflammation) occurred in 6% of the patients, of whom 4% were in the delayed group and 2% in the adjuvant group. | 28108427 |
| Inflammation, Arthritis, Atherosclerosis | Altered Intercellular Communication | Traditional cardiovascular risk factors or inflammation: Which factors accelerate atherosclerosis in arthritis patients? | 28109577 |
| Airway structure, Asthma | Altered Intercellular Communication | Exhaled nitric oxide (eNO) is a biomarker of airway inflammation and seems to precede respiratory symptoms, such as asthma, in childhood. | 28109725 |
| Airway structure | Altered Intercellular Communication | Identifying genetic determinants of postnatal eNO levels might aid in unraveling the role of eNO in epithelial function or airway inflammation and disease. | 28109725 |
| Inflammation, Atherosclerosis | Altered Intercellular Communication | 18F-FDG PET imaging has become established for imaging inflammation in atherosclerosis in the aorta and carotid arteries. | 28109921 |
| Inflammation | Altered Intercellular Communication | The authors provide the first demonstration of successful, low-radiation (7.2 mSv) PET/MR imaging of inflammation and microcalcification activity in the coronary arteries. | 28109921 |
| Communicable Diseases, Inflammation | Altered Intercellular Communication | There are indications from experimental and observational studies that aspirin may reduce inflammation associated with infection. | 28110287 |
| Steatohepatitis, Fibrosis Assessment, Inflammation, Siderosis | Altered Intercellular Communication | Biopsy was obtained in all cases, grading liver steatosis, siderosis, inflammation, and fibrosis. | 28110367 |
| Inflammation, Fibrosis Assessment, Fatty degeneration | Altered Intercellular Communication | Calculated fat fraction measurements showed significant differences (p < 0.001) among steatosis grades, being unaffected by the presence of inflammation or fibrosis (p >= 0.05). | 28110367 |
| Inflammation, Fibrosis Assessment, Fatty degeneration | Altered Intercellular Communication | Calculated R2* values were not different across grades of steatosis, inflammation, and fibrosis (p >= 0.05). | 28110367 |
| Hepatitis, Liver diseases, Steatohepatitis, Fibrosis Assessment, Siderosis | Altered Intercellular Communication | A MECSE-MR sequence simultaneously quantifies liver steatosis and siderosis, regardless coexisting liver inflammation or fibrosis, with high accuracy in a wide spectrum of diffuse liver disorders. | 28110367 |
| Inflammation, Chronic disease | Altered Intercellular Communication | To test the association of low-grade inflammation with socioeconomic status (SES) and determine the relative contribution of prevalent chronic diseases and health-related behaviours in explaining such association. | 28110395 |
| Inflammation, Chronic disease | Altered Intercellular Communication | Adiposity and body mass index showed a prominent role, while prevalent chronic diseases and conditions only marginally attenuated SES inequalities in inflammation. | 28110395 |
| Chronic lymphocytic inflammation, Pontine structure, Clippers, Chronic inflammatory disorder | Altered Intercellular Communication | Chronic Lymphocytic Inflammation with Pontine Perivascular Enhancement Responsive to Steroids (CLIPPERS) is a rare chronic inflammatory disorder of the central nervous system. | 28110629 |
| Deficit, Inflammation, Neurotoxicity Syndromes | Altered Intercellular Communication | The differential metabolites reflect pathophysiological processes of inflammation, energy deficit, oxidative stress, neurotoxicity, neuro excitation and injury. | 28111353 |
| Seroconversion, Hepatic inflammation, Hepatitis B | Altered Intercellular Communication | Hepatitis B e seroconversion, associated with preceding hepatic inflammation, marks the transition from immune active to residual phase in the natural disease history of chronic hepatitis B. | 28111892 |
| Hepatic inflammation, Hepatitis B | Altered Intercellular Communication | Recently, interleukin-27 has been reported to be associated with hepatic inflammation in hepatitis B infection. | 28111892 |
| Fibrosis Assessment, Hepatitis, VHL protein, human | Altered Intercellular Communication | Overexpression of VHL attenuated liver fibrosis, downregulated fibrogenic genes, and inhibited liver inflammation, apoptosis, and angiogenesis. | 28112200 |
| Inflammation | Altered Intercellular Communication | Myokines have anti-inflammatory properties and thereby reduce low-grade inflammation. | 28112528 |
| Inflammation, Toxic effect | Altered Intercellular Communication | Two dietary polyphenols, fisetin and luteolin, reduce inflammation but augment DNA damage-induced toxicity in human RPE cells. | 28113103 |
| methyldopa, Inflammation, Chronic disease | Altered Intercellular Communication | In recent years, several studies have investigated their potential benefits for treating chronic diseases associated with prolonged inflammation and excessive oxidative stress, such as age-related macular degeneration (AMD). | 28113103 |
| Inflammation, Mortality, Premature | Altered Intercellular Communication | Our study suggests that inflammation pathways reported by these biomarkers only have a limited role in causing premature RBC death. | 28114136 |
| Pain Distress Question, Inflammation | Altered Intercellular Communication | Pain perception, intraoral inflammation (InIn), and extraoral inflammation (ExIn) data were collected 3, 7, and 14 days after surgery. | 28114265 |
| Inflammation, Metabolic Syndrome X, Neurotoxicity Syndromes, Chronic Polyneuropathy | Altered Intercellular Communication | Metabolic Syndrome, Neurotoxic 1-Deoxysphingolipids and Nervous Tissue Inflammation in Chronic Idiopathic Axonal Polyneuropathy (CIAP). | 28114358 |
| Inflammation, Neurotoxicity Syndromes, Disease of capillaries, Metabolic Syndrome X | Altered Intercellular Communication | We studied the potential role of the metabolic syndrome, neurotoxic 1-deoxysphingolipids (1-deoxySLs), microangiopathy and inflammation in sural nerve biopsies. | 28114358 |
| prostatitis | Altered Intercellular Communication | Prevalence of chronic prostatic inflammation based on clinical diagnostic criteria in a real-practice setting: a nation-wide observational study. | 28114753 |
| Benign prostatic hypertrophy, prostatitis | Altered Intercellular Communication | Chronic prostatic inflammation has a key role in the pathogenesis and progression of benign prostatic hyperplasia (BPH). | 28114753 |
| Inflammation | Altered Intercellular Communication | Thus, the identification of patients with chronic inflammation is mandatory for Urologists. | 28114753 |
| Lower Urinary Tract Symptoms, prostatitis | Altered Intercellular Communication | Patients were allocated into four diagnosis group: patients with BPH; patients with BPH and chronic prostate inflammation; patients with chronic prostate inflammation alone; and patients with lower urinary tract symptoms (LUTS) due to other causes. | 28114753 |
| Inflammation, prostatitis | Altered Intercellular Communication | BPH diagnosis with or without concomitant prostate inflammation was more frequent in older patients, while inflammation alone was prevalent in younger patients. | 28114753 |
| Communicable Diseases, Inflammation, Calcified (qualifier), Acute and chronic inflammation | Altered Intercellular Communication | Predictive factors for diagnosis of inflammation in all patients, regardless of age, were normal urinary flow (OR=2.73) and proved in-fection (OR=5.90), while in older patients (>61 years) diagnosis of chronic prostatic inflammation was specifically predicted by higher PSA values (>=4 ng/mL; OR=2.91), normal prostate volume (OR=10.23), mild symptoms (IPSS <8; OR=1.84), presence of intraprostatic calcifications (OR=4.55), and the combination of both infection and calcifications (OR=10.79). | 28114753 |
| prostatitis | Altered Intercellular Communication | In daily practice, the presence of chronic prostatic inflammation is underestimated. | 28114753 |
| Lower Urinary Tract Symptoms, prostatitis | Altered Intercellular Communication | A stricter application of established diagnostic criteria suggested would increase the detection rate of chronic prostatic inflammation and potentially change the therapeutic approach in many patients with LUTS. | 28114753 |
| Granulomatous inflammation | Altered Intercellular Communication | Samples sent from material curetted from sinus yielded no organism but histopathology reported granulomatous inflammation. | 28114858 |
| Blindness, GCA gene, Giant Cell Arteritis, Cerebrovascular accident, Have Autoimmune or Inflammatory Condition, Aortic Arch Syndromes | Altered Intercellular Communication | Giant cell arteritis (GCA) causes autoimmune inflammation of the aorta and its large branches, resulting in aortic arch syndrome, blindness, and stroke. | 28115719 |
| ARCN1 gene, Inflammation | Altered Intercellular Communication | B-IMT was significantly associated with systemic inflammation (interleukin-6 [IL-6]; r=0.365, P=0.006) and ADMA (r=0.331, P=0.013) in COPD. | 28115840 |
| ARCN1 gene, Inflammation | Altered Intercellular Communication | B-IMT is significantly increased in patients with COPD and is associated with systemic inflammation and ADMA levels. | 28115840 |
| Overweight | Altered Intercellular Communication | Ferritin Is a Marker of Inflammation rather than Iron Deficiency in Overweight and Obese People. | 28116148 |
| Inflammation, Overweight | Altered Intercellular Communication | To investigate the role of ferritin in overweight and obese people, either as a marker of inflammation or iron deficiency. | 28116148 |
| Inflammation, Ferritin, Overweight | Altered Intercellular Communication | Ferritin is a marker of inflammation rather than iron status in overweight and obese people. | 28116148 |
| Inflammation | Altered Intercellular Communication | Platelet endothelial cell adhesion molecule-1 (PECAM-1) plays a key role in the transendothelial migration of circulating leukocytes during inflammation and in the maintenance of vascular endothelial integrity. | 28116228 |
| Arthritis | Altered Intercellular Communication | * DCE-MRI biomarkers are feasible in large multicentre studies of joint inflammation. | 28116513 |
| Neurogenic Inflammation, Pruritus | Altered Intercellular Communication | This vehicle-controlled, double-blinded study investigated the effect of topical capsaicin 8% after 1- and 24-h application on evoked itch, neurogenic inflammation and itch-associated dysaesthesia. | 28117875 |
| Neurogenic Inflammation | Altered Intercellular Communication | Furthermore, 24-h capsaicin pretreatment abolished punctuate hyperknesis and lowered histamine-induced neurogenic inflammation but did not affect weal reactions. | 28117875 |
| PROS1 gene, Inflammation, Refractory anemias | Altered Intercellular Communication | However, patients with PsA in remission are characterised by a higher degree of residual synovial inflammation than patients with RA in remission, despite PDUS negativity under TNF inhibition. | 28119289 |
| Inflammation, Thrombosis, Stasis, Heart failure | Altered Intercellular Communication | Thrombosis within the vascular system in relation to inflammation and stasis is potentially associated with poor prognosis in patients with heart failure. | 28120034 |
| Inflammation, Congenital Disorders, Neoplasms, Bone Marrow Diseases, Infection, Post-Traumatic Stress Disorder | Altered Intercellular Communication | These include congenital disorders, chronic inflammation, neoplasms, infections, and posttraumatic conditions that could all result in CVJ compression and myelopathy Endoscopic-assisted procedures have been further developed for CVJ decompression and they have now become conventional approaches. | 28120062 |
| Esophagogastric Junction, Primary malignant neoplasm | Altered Intercellular Communication | Bisphosphonate, tetracycline and spironolactone use has been shown to increase gastro-oesophageal inflammation, an accepted risk factor for cancer. | 28120338 |
| Inflammation, Dermatitis | Altered Intercellular Communication | Topical cosmetic agents may play a role in the management of facial seborrheic dermatitis by reducing inflammation and scale production. | 28121079 |
| Inflammation, Osteoporosis | Altered Intercellular Communication | Inflammation as a contributing factor among postmenopausal Saudi women with osteoporosis. | 28121926 |
| Inflammation, Osteoporosis | Altered Intercellular Communication | Findings of the present study implicate a role for cytokine pattern-mediated inflammation in patients with osteoporosis. | 28121926 |
| Osteoporosis, Osteopenia | Altered Intercellular Communication | Recently, the most prevalent form of clinically significant osteopenia and osteoporosis involves various inflammatory conditions. | 28121926 |
| Inflammation, Fracture, Diabetes Mellitus | Altered Intercellular Communication | Not only aging, low bone mineral density and history of previous fracture, but also diabetes mellitus and inflammation are regarded as risk factors for fracture. | 28122172 |
| Autoimmune Diseases, Inflammation, Bone Diseases, Hyperostosis, Sternocostoclavicular | Altered Intercellular Communication | The high prevalence of autoimmune disease in patients with sternocostoclavicular hyperostosis and their first-degree relatives suggests that autoimmunity may play a role in the still elusive pathophysiology of the intriguing osteogenic response to inflammation observed in this rare bone disorder. | 28122596 |
| Cartilage destruction, Inflammation | Altered Intercellular Communication | Inflammation is a major cause of cartilage destruction and leads to the imbalance of metabolic activities in the arthritic joint. | 28122611 |
| Inflammation | Altered Intercellular Communication | This is the first study identifying a specific role for PEDF in joint inflammation and highlights the multi-faceted activities of PEDF. | 28122611 |
| Inflammation, Disorder of tendon | Altered Intercellular Communication | Growing evidence supports a key role for inflammation in the onset and progression of tendinopathy. | 28122639 |
| Inflammation, Disorder of tendon | Altered Intercellular Communication | Persistent stromal fibroblast activation may be implicated in the development of chronic inflammation and recurrent tendinopathy. | 28122639 |
| Inflammation, Periodontitis | Altered Intercellular Communication | Periodontitis is a chronic oral pathology caused by impaired immune response against oral bacteria resulting in tissue inflammation and damage. | 28122660 |
| Enteritis, physiopathological | Altered Intercellular Communication | Environmental enteric dysfunction (EED), a condition characterized by small intestine inflammation and abnormal gut permeability, is widespread in children in developing countries and a major cause of growth failure. | 28122695 |
| Inflammation, Primary malignant neoplasm | Altered Intercellular Communication | Recent studies have demonstrated the role of systemic inflammation in the development and progression of cancer. | 28124528 |
| Inflammation, Rheumatoid Arthritis | Altered Intercellular Communication | Monitoring total-body inflammation and damage in joints and entheses: the first follow-up study of whole-body magnetic resonance imaging in rheumatoid arthritis. | 28125360 |
| Inflammation, Edema of bone marrow, Synovitis, Erosion of bone, Enthesitis | Altered Intercellular Communication | The intrareader agreement was high for bone marrow oedema (BMO), bone erosion (80-100%), and enthesitis (77-100%), and slightly lower for synovitis and soft tissue inflammation (50-100%). | 28125360 |
| Inflammation, Synovitis | Altered Intercellular Communication | All synovitis, BMO, and soft tissue inflammation counts decreased numerically during treatment. | 28125360 |
| MTA2 gene, Inflammation, Pelvic Inflammatory Disease | Altered Intercellular Communication | Pelvic inflammatory disease (PID) is a clinical syndrome of the female reproductive tract characterized by inflammation of the endometrium, fallopian tubes, or peritoneum (1). | 28125569 |
| Pneumonitis | Altered Intercellular Communication | We have previously shown that mice lacking the ability to generate Vasoactive Intestinal Peptide (VIP) develop spontaneous PH, pulmonary arterial remodeling and lung inflammation. | 28125639 |
| Inflammation, Helicobacter pylori, Stomach Carcinoma, Communicable Diseases, precancerous lesions | Altered Intercellular Communication | Helicobacter pylori (H. pylori) infection induces inflammation of the gastric mucosa, which may progress to precancerous lesions leading to gastric cancer. | 28125638 |
| Presenile dementia, Inflammation, Mental disorders | Altered Intercellular Communication | DMN brain systems have been implicated in diverse social, cognitive, and affective processes, as well as risk for forms of dementia and psychiatric disorders that associate with systemic inflammation. | 28126500 |
| Inflammation | Altered Intercellular Communication | These novel findings offer evidence for a unique association between a marker of systemic inflammation (IL-6) and ACC and mPFC functional connectivity within the DMN, a network that may be important for linking aspects of immune function to psychological and behavioral states in health and disease. | 28126500 |
| Anemia | Altered Intercellular Communication | Elevated Plasma Neutrophil Gelatinase-Associated Lipocalin Level as a Risk Factor for Anemia in Patients with Systemic Inflammation. | 28127551 |
| Inflammation, Anemia | Altered Intercellular Communication | This study investigated the relationships between plasma NGAL levels and indices of anemia in 187 patients with systemic inflammation. | 28127551 |
| Inflammation, Anemia | Altered Intercellular Communication | In conclusion, enhanced NGAL production may contribute to the development of anemia in patients with systemic inflammation. | 28127551 |
| Inflammation, Nasal Polyps, Chronic sinusitis | Altered Intercellular Communication | T2 inflammation of chronic rhinosinusitis with nasal polyps (CRSwNP) may be influenced by epithelial cytokines release (TSLP, IL-25, and IL-33). | 28127565 |
| Inflammation, Organ Dysfunction Scores, Acute Cholecystitis | Altered Intercellular Communication | According to the Tokyo Guidelines, severity of acute cholecystitis is divided into three grades based on the degree of inflammation and the presence of organ dysfunction. | 28127715 |
| Liver carcinoma | Altered Intercellular Communication | Lymphocyte to monocyte ratio and neutrophil to lymphocyte ratio are superior inflammation-based predictors of recurrence in patients with hepatocellular carcinoma after hepatic resection. | 28127774 |
| Liver carcinoma, FAM126A gene | Altered Intercellular Communication | The purpose of this study was to investigate which inflammation-based marker more accurately predict recurrence in patients receiving hepatectomy for hepatocellular carcinoma (HCC). | 28127774 |
| Inflammation, muscle mass, Skeletal muscle hypertrophy | Altered Intercellular Communication | Resistance training during hospitalization increases skeletal muscle mass, and patients with high levels of systemic inflammation demonstrate less ability to increase or preserve muscle mass in response to resistance training during illness. | 28129234 |
| Inflammation, Ulceration, CTCAE, Granuloma, Crohn Disease | Altered Intercellular Communication | Both patients had evidence of inflammation, ulceration, and granulomas consistent with Crohn's disease, and responded well to immunosuppression. | 28129697 |
| Inflammation | Altered Intercellular Communication | Abnormal parameters associated with systemic inflammation, such as higher plateletcrit level, may facilitate the development of TASS. | 28130690 |
| Inflammation | Altered Intercellular Communication | Low-grade chronic inflammation is associated with several chronic conditions, and diet is known to play a role in chronic inflammation. | 28130829 |
| Inflammation, Malignant Neoplasms, Neoplasms | Altered Intercellular Communication | Deleted in malignant brain tumours 1 (DMBT1) exerts functions in the regulation of epithelial differentiation and inflammation and has been proposed as a tumour suppressor. | 28130841 |
| Inflammation, Fibrosis Assessment, Hypoxia | Altered Intercellular Communication | Markers of hypoxia, adipo- and angiogenesis, inflammation and fibrosis were analysed in AT and serum. | 28131740 |
| Inflammation, Sleep Apnea, Obstructive | Altered Intercellular Communication | Resting AT blood flow was higher in OSAS compared to controls (108.5+-22.7 vs. 78.9+-24.9au, P<0.005) and strongly associated with inflammation markers IL-6 and MCP-1. | 28131740 |
| Inflammation, Fibrosis Assessment, Sleep Apnea, Obstructive | Altered Intercellular Communication | AT of OSAS subjects showed increased inflammation (TNFA P=0.049) and fibrosis (COL3A1 P=0.02), a trend of higher HIF1A expression (P=0.06) and reduced adipogenesis (PPARG P=0.006). | 28131740 |
| Inflammation, Fibrosis Assessment, Structure of bronchial artery | Altered Intercellular Communication | In contrast, both lungs showed clear signs of chronic inflammation and fibrosis that could be the cause of bronchial artery hypertrophy. | 28132091 |
| Inflammation, Subretinal deposits | Altered Intercellular Communication | There are no disease-altering therapies for dry AMD, which is characterized by accumulation of subretinal drusen deposits and complement-driven inflammation. | 28132833 |
| Inflammation, Heart failure | Altered Intercellular Communication | Background In patients with heart failure, inflammation has been associated with worse functional capacity, but it is uncertain whether it could affect their response to exercise training. | 28134562 |
| Drug Eruptions, Inflammation, Parakeratosis, Spongiosis | Altered Intercellular Communication | In several skin biopsies, histologic features supporting a lichenoid drug eruption were present, including parakeratosis, spongiosis, periadnexal/perivascular inflammation, and eosinophils. | 28134729 |
| Inflammation, Dental Plaque | Altered Intercellular Communication | Free PAI-1 and TAFI stabilize active plaque area by inhibition of fibrinolysis and inflammation. | 28135035 |
| Inflammation | Altered Intercellular Communication | CD68 was highly associated with VWF, PAI-1 and especially TAFI, underlining the role of macrophages in fibrinolytic activity and inflammation. | 28135035 |
| Inflammation, Dental Plaque | Altered Intercellular Communication | Conclusion The abundance of free PAI-1 and TAFI in the plaque may inhibit plasmin generation and thereby counteract plaque destabilization by fibrinolysis, cell migration and inflammation. | 28135035 |
| Lymphedema, Cellulitis | Altered Intercellular Communication | Lymphedema is an irreversible inflammatory condition caused by accumulated lymph fluid and is associated with chronic swelling and increased risk of cellulitis. | 28135124 |
| Inflammation, Chronic pain | Altered Intercellular Communication | They can result in chronic inflammation, reduced mobility, and chronic pain. | 28135201 |
| Inflammation, Attempt | Altered Intercellular Communication | Blunted HPA axis activity prior to suicide attempt and increased inflammation in attempters. | 28135675 |
| Inflammation, Gain, Colorectal Carcinoma | Altered Intercellular Communication | The current study is designed to gain a better understanding of the role of a healthy diet aimed at dampening inflammation and oxidative stress on long-term disease outcomes and survival in colorectal cancer patients. | 28137255 |
| allergic inflammation, Eosinophilic inflammation | Altered Intercellular Communication | Recently, the innate Th2 response is revealed to induce eosinophil infiltration in allergic inflammation, however the role of the innate Th2 response has not been studies in AERD. | 28137499 |
| palladium, Inflammation, Depression, CTCAE | Altered Intercellular Communication | Given that inflammation plays a role in both PD and depression, it is intriguing that peripheral p11 levels are altered in immune cells in both conditions. | 28137881 |
| Inflammation, Fibrosis Assessment | Altered Intercellular Communication | Thus, MPO-ANCA may promote inflammation by reducing the secretion of antiinflammatory IL-10 from monocytes, and MPO-ANCA can alter the development of macrophages and T cells to potentially promote fibrosis. | 28138552 |
| Inflammation, Neck Pain | Altered Intercellular Communication | The neck pain is due to inflammation caused by calcium hydroxyapatite crystal deposition in the tendons on the longus colli muscles. | 28139306 |
| Inflammation, Glaucoma, CTCAE | Altered Intercellular Communication | Oxidized low-density lipoprotein, lipid and calcium aggregates reveal oxidative stress and inflammation in the conjunctiva of glaucoma patients. | 28139882 |
| Inflammation, Glaucoma, CTCAE | Altered Intercellular Communication | The lipid-mediated alterations suggested the presence of oxidative stress and inflammation in the conjunctiva of glaucoma patients. | 28139882 |
| Inflammation, Failure (biologic function) | Altered Intercellular Communication | The present data further support the role of oxidative stress and inflammation in the wound healing process leading to excessive scarring and failure in DS surgery. | 28139882 |
| Portal vein structure, Inflammation | Altered Intercellular Communication | Portal vein stenosis develops due to different causes including postoperative inflammation and oncological processes. | 28143477 |
| Inflammation, B-Cell Lymphomas | Altered Intercellular Communication | Epstein-Barr virus (EBV) is associated with B-cell lymphoma in various conditions, such as immunodeficiency and chronic inflammation. | 28143608 |
| Inflammation, Asthma | Altered Intercellular Communication | Cluster 2 was composed of patients with a mix of patients with nonsevere and severe asthma with marginal inflammation who exhibited airway luminal narrowing without wall thickening. | 28143694 |
| Adverse reaction to drug, Acute inflammation, Edema | Altered Intercellular Communication | When sodium aescinate is given to surgical inpatients to treat postoperative inflammation and oedema, adverse drug reactions and drug-drug interactions must be closely monitored. | 28144968 |
| Degenerative polyarthritis, Inflammation | Altered Intercellular Communication | Smoking was associated with less radiographic hand OA whereas alcohol consumption was associated with present joint inflammation in hand OA. | 28145147 |
| Pneumonitis | Altered Intercellular Communication | Elevated GDF-15 contributes to pulmonary inflammation upon cigarette smoke exposure. | 28145442 |
| Inflammation, Cachexia | Altered Intercellular Communication | Growth differentiation factor (GDF)-15, a member of the TGF-b superfamily, is involved in inflammation, mucus secretion, and cachexia. | 28145442 |
| Pneumonitis | Altered Intercellular Communication | Importantly, GDF-15 deficiency attenuated the CS-induced pulmonary inflammation. | 28145442 |
| Pneumonitis | Altered Intercellular Communication | These results suggest that increased GDF-15-as observed in lungs of smokers and patients with COPD-contributes to CS-induced pulmonary inflammation. | 28145442 |
| Acute Kidney Injury, CTCAE, Inflammation, Kidney Failure, Acute | Altered Intercellular Communication | Serum prealbumin is a clinically relevant indicator of nutritional status and inflammation in patients with acute kidney injury (AKI). | 28145481 |
| Inflammation, Muscular Atrophy, Abnormal degeneration | Altered Intercellular Communication | Markers of vascularity; inflammation; fat distribution; and muscle atrophy, degeneration, and regeneration were quantified. | 28145949 |
| Inflammation, Atrophic, Muscle (organ) | Altered Intercellular Communication | Dramatic degeneration and inflammation of the rotator cuff muscles are characteristics of the most chronic and severe rotator cuff disease states, suggesting that muscle loss is more complicated than, and distinct from, the simple atrophy found in less severe cases. | 28145949 |
| Inflammation, Myocardial dysfunction | Altered Intercellular Communication | Up-regulation of miR-135a could aggravate sepsis-induced inflammation and myocardial dysfunction via activation of p38 MAPK/NF-kB pathway. | 28147298 |
| Inflammatory Bowel Diseases, Inflammation, Infectious colitis, Ulcerative Colitis | Altered Intercellular Communication | Histological evaluation revealed acute inflammation without architectural distortion consistent with either acute infectious colitis or new inflammatory bowel disease, favoring UC. | 28147350 |
| Kidney Failure, Chronic | Altered Intercellular Communication | Further evaluation of novel hormonal agents in end-stage renal disease patients should be encouraged as this population is typically excluded from clinical trials. | 28147927 |
| F11 gene, vascular inflammations | Altered Intercellular Communication | The resulting vascular inflammation and dysfunction was mediated by activation of thrombin-driven factor XI (FXI) feedback, independent of factor XII. | 28148841 |
| Hypertension, CTCAE, physiopathological, Cardiovascular Diseases | Altered Intercellular Communication | Our results outline a coagulation-inflammation circuit that promotes vascular dysfunction, and highlight the possible utility of FXI-targeted anticoagulants in treating hypertension, beyond their application as antithrombotic agents in cardiovascular disease. | 28148841 |
| Inflammation, cervical cancer | Altered Intercellular Communication | Predictive value of hematological markers of systemic inflammation for managing cervical cancer. | 28148894 |
| Inflammation, Malignant Neoplasms | Altered Intercellular Communication | The neutrophil/lymphocyte ratio (NLR), platelet/lymphocyte ratio (PLR), and red cell distribution width (RDW) are markers of systemic inflammation with prognostic significance for cancers. | 28148894 |
| Inflammation Mediators, IL13 gene, Chronic disease | Altered Intercellular Communication | Allergic rhinitis is a common chronic disorder characterized by immunoglobulin E-mediated inflammation. | 28149331 |
| Inflammation, Blood Clot, Hypoxia | Altered Intercellular Communication | The aim of this study was to allocate distinct cellular processes playing a role in thrombus resolution, such as inflammation, hypoxia, proliferation, apoptosis and angiogenesis, to different stages of thrombofibrotic remodelling. | 28150849 |
| Inflammation, Primary malignant neoplasm | Altered Intercellular Communication | Hematologic parameters of systemic inflammation are receiving attention as promising prognostic indicators in cancer patients. | 28151879 |
| Inflammation, Cardiovascular Diseases | Altered Intercellular Communication | In recent years, the predictive and prognostic value of the red cell distribution width (RDW) as an indicator of inflammation has been shown in many cardiovascular diseases. | 28151892 |
| vascular inflammations | Altered Intercellular Communication | Enhanced vascular inflammation is also implicated as one of the pathophysiologic mechanisms in CAD. | 28153212 |
| Sleep-Disordered Breathing, Inflammation | Altered Intercellular Communication | Nocturnal intermittent hypoxia and short sleep duration were independently associated with elevated serum CRP level in CAD patients, suggesting that both SDB and sleep shortage are associated with enhanced inflammation in CAD patients. | 28153212 |
| Inflammation, Anemia | Altered Intercellular Communication | Approximately two-thirds of anemia in American elderly is caused by chronic inflammation or is unexplained. | 28153527 |
| Inflammation | Altered Intercellular Communication | A potential contributing factor may include air pollution exposures, which have been shown to increase systemic inflammation and affect erythropoiesis. | 28153527 |
| Inflammatory abnormality of the eye | Altered Intercellular Communication | Remission was defined as absence of progressive scarring and active ocular inflammation for >= 2 months. | 28154932 |
| Inflammation | Altered Intercellular Communication | Systemic inflammation was suggested as an important prognostic factor for outcomes. | 28154994 |
| Heart failure, myocardial injury | Altered Intercellular Communication | Acute Effects of Implantable Cardioverter-Defibrillator Shocks on Biomarkers of Myocardial Injury, Apoptosis, Heart Failure, and Systemic Inflammation. | 28156007 |
| Inflammation, myocardial injury | Altered Intercellular Communication | Biomarkers indicative of myocardial injury, inflammation, and apoptosis were measured before and after implantation, and compared between patients receiving DFT (DFT+) to those not (DFT-). | 28156007 |
| myocardial injury | Altered Intercellular Communication | Implantable cardioverter-defibrillator (ICD) shocks are potentially associated with myocardial injury, altered hemodynamics, apoptosis, and inflammatory signaling. | 28156007 |
| Inflammation, Neoplasms | Altered Intercellular Communication | This may be secondary to other processes such as tumor biology and inflammation. | 28156177 |
| Inflammation, Carcinogenesis | Altered Intercellular Communication | Single-nucleotide polymorphisms (SNPs) in cytokine genes can affect gene expression and thereby modulate inflammation and carcinogenesis. | 28157220 |
| Inflammation, Uveitis | Altered Intercellular Communication | Anterior and non-granulomatous uveitis was the most common types of inflammation. | 28157425 |
| Cataract, Inflammation | Altered Intercellular Communication | A longer duration of symptoms as well as anterior inflammation demonstrated an increased risk for cataract formation. | 28157425 |
| Inflammation | Altered Intercellular Communication | In addition, patients suffering from CF display chronic inflammation that contributes to the pathogenesis of CF. | 28158236 |
| Inflammation | Altered Intercellular Communication | Recent work suggests that CF patients have a reduced capacity to biosynthesize specialized pro-resolving lipid mediators (SPMs), which contributes to the development and duration of the unwanted inflammation. | 28158236 |
| Airway structure | Altered Intercellular Communication | Alterations in the metabolism of arachidonic acid (AA) and docosahexaenoic acid (DHA) to specialized pro-resolving mediators (SPMs), like lipoxins (LXs), maresins (MaRs), protectins (PDs) and resolvins (Rvs), may play a major role on clinical impact of airway inflammation in CF. | 28158236 |
| Parakeratosis, Intraepithelial Lymphocytosis, Acute inflammation, Bacterial resistance | Altered Intercellular Communication | Important histologic clues included superficial and detached fragments of desquamated and hyper-pink parakeratosis, acute inflammation, intraepithelial lymphocytosis, dead keratinocytes, and bacterial overgrowth. | 28158394 |
| Inflammation, Nerve Degeneration | Altered Intercellular Communication | Regional Gene Expression of Inflammation and Oxidative Stress Responses Does Not Predict Neurodegeneration in Aging. | 28158670 |
| Airway structure | Altered Intercellular Communication | Arsenic exposure alters lung function and airway inflammation in children: A cohort study in rural Bangladesh. | 28159392 |
| Airway structure, Reduced Device Function | Altered Intercellular Communication | We aim to examine whether prenatal and childhood arsenic exposure is associated with reduced lung function and increased airway inflammation in school-aged children. | 28159392 |
| Airway structure, Impaired lung function | Altered Intercellular Communication | In conclusion, our findings suggest that prenatal arsenic exposure is related to impaired lung function, while childhood exposure may increase airway inflammation, particularly in boys. | 28159392 |
| Inflammation, Thrombosis, Cardiovascular Diseases | Altered Intercellular Communication | Particulate and gaseous pollutants on inflammation, thrombosis, and autonomic imbalance in subjects at risk for cardiovascular disease. | 28159399 |
| Presenile dementia, Inflammation | Altered Intercellular Communication | Many studies have investigated the association between markers for peripheral inflammation and risk of dementia, but the results have been conflicting. | 28159467 |
| Cessation of life, Inflammation, Presenile dementia, Cerebrovascular accident | Altered Intercellular Communication | A Cox proportional hazard model and Fine and Grays model were adjusted for stroke and competing risk of death to estimate the association between inflammation and development of dementia. | 28159467 |
| Inflammation, Neoplasms, Fibrosis Assessment, Hepatitis C, FAM126A gene | Altered Intercellular Communication | We demonstrate that tumour suppressor protein tyrosine phosphatase receptor delta (PTPRD) is impaired by HCV infection in vivo and in HCC lesions of paired liver biopsies independent from tissue inflammation or fibrosis. | 28159835 |
| Inflammation, Chronic Kidney Diseases, Obesity | Altered Intercellular Communication | Metabolically healthy obesity and incident chronic kidney disease: The role of systemic inflammation in a prospective study. | 28160438 |
| Inflammation, Units Of Measure - Siemens, Chronic Kidney Diseases, Obesity | Altered Intercellular Communication | To investigate the association between the metabolically healthy obesity (MHO) phenotype and incident chronic kidney disease (CKD) in a Chinese population and whether systemic inflammation affects this association. | 28160438 |
| Inflammation, Units Of Measure - Siemens, Chronic Kidney Diseases | Altered Intercellular Communication | MHO was significantly associated with incident CKD, and the level of systemic inflammation partially explained this association. | 28160438 |
| Inflammation | Altered Intercellular Communication | Aging is associated with a decline in autophagy and a state of low-grade inflammation which further affects apoptosis and autophagy. | 28160545 |
| Inflammation, Prostate carcinoma | Altered Intercellular Communication | Importantly, we found no correlation between serum ferritin levels and the inflammation marker C-reactive protein (CRP) in prostate cancer patients. | 28160568 |
| Inflammation, Traumatic injury | Altered Intercellular Communication | Triester glycerol oxide gel (Protefix(r) Queisser Pharma, Germany) is a new topical agent that has the property of adherence to the oral mucosa by forming a lipid film which protects against mechanical trauma and may help to reduce oral tissue moisture loss and inflammation. | 28160585 |
| Inflammation | Altered Intercellular Communication | These results show new possible mechanisms connecting androgens to insulin resistance and chronic inflammation. | 28161330 |
| Cerebral Amyloid Angiopathy, Inflammation, Granulomatous, Vasculitis, CTCAE, Vasculitis, Abra (invertebrate) | Altered Intercellular Communication | Amyloid-b-related angiitis (ABRA) is a rare complication of cerebral amyloid angiopathy in which amyloid-b deposition in the leptomeningeal and cortical vessels is associated with vasculitis characterized by transmural lymphohistiocytic, often granulomatous, inflammation. | 28161339 |
| Presenile dementia, Inflammation, Impaired cognition | Altered Intercellular Communication | Studies on markers of inflammation in subjects with mild cognitive impairment or AD dementia provided inconsistent results. | 28161476 |
| Inflammation, Data types - Address, Trauma, Nervous System | Altered Intercellular Communication | an AD CSF biomarker profile) and to investigate associations of inflammation markers with CSF biomarkers of amyloid, tau pathology, and neuronal injury. | 28161476 |
| Inflammation, Vascular System Injuries | Altered Intercellular Communication | The best predictive models included 8 serum or 3 CSF neuroinflammatory markers related to cytokine mediated inflammation, vascular injury, and angiogenesis. | 28161476 |
| Inflammation, Vascular System Injuries | Altered Intercellular Communication | Our results suggest that inflammation, vascular injury, and angiogenesis as reflected by CSF markers are closely related to cerebral tau pathology. | 28161476 |
| Inflammation, Traumatic injury | Altered Intercellular Communication | Gender and a proxy of menopause were associated with various features of inflammation and injury in DILI. | 28161910 |
| Communicable Diseases, Inflammation | Altered Intercellular Communication | Although no infection or inflammation occurred at the surgical site, the patient requested removal of the PPE implant for aesthetic reasons alone at 1 year after the surgery. | 28162855 |
| Inflammation | Altered Intercellular Communication | Maltodextrin/ascorbic acid stimulates wound closure by increasing collagen turnover and TGF-b1 expression in vitro and changing the stage of inflammation from chronic to acute in vivo. | 28162862 |
| Inflammation, artery calcification | Altered Intercellular Communication | Inflammation plays a central role in atherogenesis and artery calcification. | 28162903 |
| Heart failure | Altered Intercellular Communication | Plasma Zonulin and its Association with Kidney Function, Severity of Heart Failure, and Metabolic Inflammation. | 28164545 |
| Inflammation | Altered Intercellular Communication | Recent work also suggests zonulin to represent a general regulator of tissue barriers and a player in metabolic inflammation. | 28164545 |
| Inflammation, Chronic heart failure, Congestive heart failure | Altered Intercellular Communication | Here, we investigated the associations of zonulin with chronic heart failure (CHF), kidney function, and metabolic inflammation. | 28164545 |
| Inflammation, Diabetes Mellitus, Non-Insulin-Dependent, Congestive heart failure | Altered Intercellular Communication | Our study indicates zonulin involvement in metabolic inflammation in T2D, but no association with disease status in CHF. | 28164545 |
| Pneumonitis | Altered Intercellular Communication | In this study, we investigated potential changes in BTLA expression on lymphocytes in patients with severe CAP and determined how BTLA expression affects a model of LPS-induced acute lung inflammation. | 28164546 |
| Pneumonitis | Altered Intercellular Communication | The percentages of circulating BTLA+CD4+ lymphocytes were determined in patients with severe CAP and in an LPS-induced acute lung inflammation model. | 28164546 |
| Pneumonitis | Altered Intercellular Communication | The percentages of circulating BTLA+CD4+ lymphocytes were significantly higher in patients with severe CAP and in mice with LPS-induced acute lung inflammation than in the control groups. | 28164546 |
| Pneumonitis | Altered Intercellular Communication | After treatment with either dexamethasone or the agonistic anti-BTLA antibody 6A6, BTLA expression was significantly higher than that in the control mice with LPS-induced acute lung inflammation. | 28164546 |
| Sepsis, Cessation of life | Altered Intercellular Communication | Prognostic Value of Dynamic Monitoring of Cellular Immunity and HMGB1 in Severe Sepsis: Delayed Chronic Inflammation may be the Leading Cause of Death in Late Severe Sepsis. | 28164547 |
| Sepsis, Inflammation, Immune System Diseases, Cessation of life | Altered Intercellular Communication | Patients with severe sepsis present with cellular immune dysfunction and persistent chronic inflammation, both of which may lead to death in the late phase of severe sepsis. | 28164547 |
| Sepsis, Inflammation | Altered Intercellular Communication | Dynamic monitoring of indicators of cellular immunity and HMGB1 is useful for evaluating the immune status, chronic inflammation processes, and prognoses of patients with severe sepsis. | 28164547 |
| Thoracic Injuries | Altered Intercellular Communication | Modulation of the Redox Expression and Inflammation Response in the Critically Ill Polytrauma Patient with Thoracic Injury. | 28164593 |
| Primary malignant neoplasm | Altered Intercellular Communication | Platelet to lymphocyte ratio (PLR) is widely used as an inflammation-related cancer biomarker. | 28164624 |
| Gastrointestinal inflammation | Altered Intercellular Communication | Fecal calprotectin is a noninvasive screening marker for intestinal inflammation. | 28164652 |
| airway disease, Inflammation, Smooth muscle (tissue), mucus secretion | Altered Intercellular Communication | Asthma is a chronic airway disease characterized by inflammation, mucus hypersecretion and abnormal airway smooth muscle (ASM) contraction. | 28165446 |
| Cessation of life, Crohn Disease-like Reaction | Altered Intercellular Communication | Moderate/severe peritumoral diffuse lymphoid inflammation and Crohn's disease-like reaction were associated with significantly reduced risks of CRC-specific death [adjusted hazard ratio (HR) 0.48, 95% confidence interval (CI) 0.31-0.76, and HR 0.60, 95% CI 0.42-0.84, respectively]. | 28165633 |
| Inflammation | Altered Intercellular Communication | Postoperative management with sinonasal debridement and combined saline/corticosteroid nasal irrigation may help to improve surgical success in patients with increased post-radiotherapy mucosal inflammation. | 28165837 |
| Inflammation, Appendicitis, CTCAE | Altered Intercellular Communication | Objective To assess the level of C-reactive protein in acute appendicitis and to relate the quantitative measurement with degree of inflammation of appendix. | 28166068 |
| Inflammation, Electrocardiogram: myocardial infarction (finding), Cerebrovascular accident | Altered Intercellular Communication | Secondary outcomes include: (1) mean change in systolic BP; (2) control of other vascular risk factors including lipids and hemoglobin A1c, (3) inflammation (C reactive protein [CRP]), (4) medication adherence, (5) lifestyle factors (smoking, diet, and physical activity), (6) estimated relative reduction in risk for recurrent stroke or myocardial infarction (MI), and (7) cost-effectiveness of the intervention versus usual care. | 28166784 |
| Inflammation, Primary malignant neoplasm, Cyclophosphamide/Vincristine/Dacarbazine Regimen, Chronic disease | Altered Intercellular Communication | Chronic low-grade inflammation has been recognised as a key underlying mechanism for several chronic diseases, including cancer and CVD. | 28166841 |
| Inflammation | Altered Intercellular Communication | Nutrition represents a host of key modifiable factors that influence chronic inflammation. | 28166841 |
| Inflammation, Observation Method - Coagulation, Thrombosis | Altered Intercellular Communication | Associations between ambient wood smoke and other particulate pollutants and biomarkers of systemic inflammation, coagulation and thrombosis in cardiac patients. | 28167447 |
| Inflammation, Observation Method - Coagulation, Thrombosis | Altered Intercellular Communication | Our study examined associations between ambient levels of a marker of wood smoke (Delta-C) and other particulate air pollutants and biomarkers of inflammation, coagulation and thrombosis. | 28167447 |
| Inflammation, Observation Method - Coagulation, Impaired T cell function | Altered Intercellular Communication | Increases in PM2.5, BC, AMP, and UFP concentrations in the previous 96h were also associated with adverse changes in markers of systemic inflammation and coagulation, but not with markers of endothelial cell dysfunction or platelet activation. | 28167447 |
| Have Autoimmune or Inflammatory Condition | Altered Intercellular Communication | However, it is known that Th17 cells exhibit considerable plasticity, particularly at sites of autoimmune inflammation. | 28167631 |
| Inflammation, Nonocclusive coronary artery atherosclerosis | Altered Intercellular Communication | We aimed to investigate whether markers of lipid metabolism, inflammation and kidney function could predict non-obstructive coronary artery disease (CAD) determined by coronary CTA, in a low-to-intermediate-risk group. | 28168796 |
| Tears body substance, Inflammation, Glaucoma, CTCAE, Dryness of eye | Altered Intercellular Communication | Determination of inmune response and inflammation mediators in tears: Changes in dry eye and glaucoma as compared to healthy controls. | 28169068 |
| Inflammation, Pain Distress Question, Structure of articular cartilage, Traumatic injury, Degenerative disorder | Altered Intercellular Communication | Loss of articular cartilage from ageing, injury or degenerative disease is commonly associated with inflammation, causing pain and accelerating degradation of the cartilage matrix. | 28170076 |
| Inflammation, Ocular surface disease | Altered Intercellular Communication | Rosacea-related cutaneous inflammation is a common cause of ocular surface disease. | 28170535 |
| vascular inflammations, Calcinosis, Chronic Kidney Diseases | Altered Intercellular Communication | Vascular inflammation and media calcification are already present in early stages of chronic kidney disease. | 28171827 |
| Calcinosis, vascular inflammations, Calcification of the aorta, Chronic Kidney Diseases | Altered Intercellular Communication | Thereby, aortic wall thickness and calcification score of aortic intima and of V. saphena were significantly higher in advanced CKD patients than in nonrenal control patients, whereas significant vascular inflammation and proosteogenic dedifferentiation of VSMC and calcification of the aortic media were already present in early CKD. | 28171827 |
| Inflammation, Calcinosis | Altered Intercellular Communication | Of note, calcium-phosphate product correlated well with markers of inflammation, but not with calcification itself. | 28171827 |
| Inflammation, Liver carcinoma, Liver Cirrhosis | Altered Intercellular Communication | Hepatocellular carcinoma usually develops in the setting of cirrhosis or chronic inflammation. | 28173830 |
| Inflammation, Colorectal Carcinoma | Altered Intercellular Communication | While the role of the gut microbiome in inflammation and colorectal cancers has received much recent attention, there are few data to support an association between the oral microbiome and head and neck squamous cell carcinomas. | 28173873 |
| Airway structure | Altered Intercellular Communication | Phthalate-induced oxidative stress and association with asthma-related airway inflammation in adolescents. | 28174042 |
| Inflammation | Altered Intercellular Communication | We hypothesized that biomarkers of inflammation predict the development and progression of DSPN in a population-based cohort. | 28174259 |
| Inflammation | Altered Intercellular Communication | The predictive value of systemic levels of eight biomarkers of inflammation was assessed for incident DSPN in 133 incident case subjects and 397 individuals without incident DSPN, and for DSPN progression in 57 patients with prevalent DSPN at both time points. | 28174259 |
| vascular inflammations | Altered Intercellular Communication | Systemic subclinical and vascular inflammation predicted both the onset and progression of DSPN over 6.5 years in an older general population. | 28174259 |
| Mycosis Fungoides, Lymphoma, T-Cell, Cutaneous, Inflammation | Altered Intercellular Communication | Cutaneous T-cell lymphomas (CTCL), especially mycosis fungoides, can be considered as a state of longstanding low-grade systemic inflammation. | 28175924 |
| Inflammation, Primary bone lymphoma | Altered Intercellular Communication | This case suggests that chronic inflammation induced by prolonged IUD insertion may contribute to the development of primary uterine lymphoma. | 28176228 |
| Inflammation | Altered Intercellular Communication | Downregulation of tricellulin causes increased permeability to macromolecules and subsequent microbial translocation contributes to systemic inflammation. | 28176790 |
| Inflammation | Altered Intercellular Communication | Interleukin (IL)-33 promotes T helper (Th)2 immunity and systemic inflammation. | 28176939 |
| Inflammation, Fibrosis Assessment | Altered Intercellular Communication | C-reactive protein (CRP) is a systemic marker of inflammation that correlates with disease status in cystic fibrosis (CF). | 28178305 |
| Inflammation, Diabetes Mellitus, Non-Insulin-Dependent | Altered Intercellular Communication | The liver-derived C-reactive protein (CRP) is a sensitive and systemic biomarker of inflammation, and has been associated with increased risk of developing type 2 diabetes in populations other than Chinese. | 28178951 |
| Inflammation | Altered Intercellular Communication | Background: Observational studies suggest an inverse association between whole-grain (WG) consumption and inflammation. | 28179226 |
| Inflammation, Asthma, Tumor necrosis | Altered Intercellular Communication | Our objective was to determine molecular phenotypes of asthma by analysing sputum cell transcriptomics from 104 moderate-to-severe asthmatic subjects and 16 nonasthmatic subjects.After filtering on the differentially expressed genes between eosinophil- and noneosinophil-associated sputum inflammation, we used unbiased hierarchical clustering on 508 differentially expressed genes and gene set variation analysis of specific gene sets.We defined three transcriptome-associated clusters (TACs): TAC1 (characterised by immune receptors IL33R, CCR3 and TSLPR), TAC2 (characterised by interferon-, tumour necrosis factor-a- and inflammasome-associated genes) and TAC3 (characterised by genes of metabolic pathways, ubiquitination and mitochondrial function). | 28179442 |
| Inflammation, Colorectal Carcinoma | Altered Intercellular Communication | Background: Diet is known to influence systemic inflammation, a recognized risk factor for colorectal cancer (CRC). | 28179489 |
| Inflammation, Cyclophosphamide/Vincristine/Dacarbazine Regimen, Cardiovascular Diseases | Altered Intercellular Communication | Background: During development of cardiovascular disease (CVD), interferon-g-mediated inflammation accelerates degradation of tryptophan into downstream metabolites. | 28179491 |
| Inflammation, Lung Injury, Idiopathic Pulmonary Fibrosis | Altered Intercellular Communication | Twist1 may shape the IPF phenotype and regulate inflammation in fibrotic lung injury. | 28179498 |
| Vasculitis, Takayasu Arteritis | Altered Intercellular Communication | 18F-FDG PET reveals unique features of large vessel inflammation in patients with Takayasu's arteritis. | 28180963 |
| Inflammation | Altered Intercellular Communication | PET/CT may be useful in the assessment of local inflammatory and vascular remodelling events independent of systemic inflammation during follow-up, even in lesions in which the arterial wall is <4 mm. | 28180963 |
| Inflammation, Fibrosis Assessment | Altered Intercellular Communication | We conclude that the transition of fibroblast to myofibroblasts via TGF-b pathway is a key linker between inflammation and fibrosis in LFH mechanism. | 28180980 |
| Inflammation | Altered Intercellular Communication | This report is apparently the first showing that adherence to MedDiet is associated with the methylation of the reported genes related to inflammation with a potential regulatory impact. | 28181167 |
| Inflammation, Ischemic stroke | Altered Intercellular Communication | Increasing evidences have demonstrated that inflammation is involved in the mechanisms of acute ischemic stroke (AIS). | 28181171 |
| Inflammation | Altered Intercellular Communication | Systemic inflammation may contribute to disability independently of clinical vascular events. | 28181636 |
| Lower Urinary Tract Symptoms, Benign prostatic hypertrophy, prostatitis | Altered Intercellular Communication | Chronic prostatic inflammation is implicated in the pathogenesis of benign prostatic hyperplasia (BPH)-associated lower urinary tract symptoms (LUTS). | 28181681 |
| prostatitis | Altered Intercellular Communication | Previous studies evaluated the degree of chronic prostatic inflammation based on histological scores, which may contain subjective factors. | 28181681 |
| Inflammation, Gastrointestinal inflammation | Altered Intercellular Communication | We previously demonstrated that the number of high endothelial venule (HEV)-like vessels correlates positively with the magnitude of inflammation in chronic inflammatory gastrointestinal diseases. | 28181681 |
| Inflammation, Lower Urinary Tract Symptoms, prostatitis | Altered Intercellular Communication | Here, we evaluated the degree of BPH-associated chronic prostate inflammation based on appearance of HEV-like vessels and determined whether the extent of inflammation correlated with LUTS severity, as evaluated by a urodynamic study. | 28181681 |
| Lower Urinary Tract Symptoms, prostatitis | Altered Intercellular Communication | We also determined whether the magnitude of chronic prostatic inflammation, as assessed by HEV-like vessel number, correlated with the degree of LUTS. | 28181681 |
| Lower Urinary Tract Symptoms, prostatitis | Altered Intercellular Communication | The number of HEV-like vessels positively correlated not only with the magnitude of chronic prostatic inflammation but also with the degree of LUTS, particularly with symptoms associated with voiding function, which was measured objectively in a pressure flow study. | 28181681 |
| Dysfunctional voiding of urine, prostatitis | Altered Intercellular Communication | Chronic prostate inflammation may promote BPH and resulting voiding dysfunction. | 28181681 |
| prostatitis | Altered Intercellular Communication | Assessment of the number of HEV-like vessels could be a surrogate for identifying the degree of chronic prostatic inflammation. | 28181681 |
| Trachoma , Inflammation | Altered Intercellular Communication | We fit the four different mechanistic models of trachoma transmission to cross-sectional age-specific Polymerase Chain Reaction (PCR) and Trachomatous inflammation, follicular (TF) prevalence data. | 28182664 |
| Inflammation, ETV3 wt Allele, Metabolic Syndrome X, Obesity | Altered Intercellular Communication | Low-grade inflammation is associated with obesity and the metabolic syndrome (MetS). | 28182820 |
| Airway structure, Refractory anemias | Altered Intercellular Communication | The association of anti-CCP with elevated cell counts and NET levels in FDRs supports a hypothesis that local airway inflammation and NET formation may drive anti-CCP production in the lung and may promote the early stages of RA development. | 28182854 |
| Inflammation, Bursitis | Altered Intercellular Communication | LCA revealed four groups: (1) bursitis with limited inflammation elsewhere (n = 1280), (2) bursitis with extensive inflammation (n = 595), (3) rotator cuff tears (n = 558) and (4) limited pathology (n = 567). | 28183338 |
| Rheumatoid Arthritis, Endothelium, Inflammation | Altered Intercellular Communication | Endothelial injury in rheumatoid arthritis: a crosstalk between dimethylarginines and systemic inflammation. | 28183353 |
| Arterial Stiffness, Inflammation | Altered Intercellular Communication | Significant interactions with inflammation were detected in the associations between ACh and both SDMA (p = 0.014) and ADMA:SDMA ratio (p = 0.027), as well as between SNP and SDMA (p = 0.042) and between arterial stiffness and ADMA:SDMA (p = 0.036), with the associations being stronger in the patients with high inflammatory markers in each case. | 28183353 |
| Refractory anemias, Inflammation, Endothelium, Disease remission | Altered Intercellular Communication | Besides their emerging role as markers of endothelial dysfunction SDMA and ADMA may promote endothelial injury in RA as mediators of the adverse effects of systemic inflammation on micro- and macrovasculature respectively in patients with active disease. | 28183353 |
| Inflammation | Altered Intercellular Communication | Nevertheless, dietary saturated fatty acids increased LCn-3PUFA in plasma and tissue lipids compared with n-6PUFA, potentially reducing other cardiovascular risk factors such as inflammation and clotting tendency. | 28183443 |
| Inflammatory disease of mucous membrane, Osteopenia | Altered Intercellular Communication | All patients reported with mucosa inflammation and bone loss and/or implant failures to the first annual examination were identified. | 28185409 |
| Inflammation | Altered Intercellular Communication | Highest risk for early inflammation was observed for patients at an age of 50-55 years at surgery (P < .05). | 28185409 |
| ARCN1 gene, Inflammation, Chronic Obstructive Airway Disease, Communicable Diseases | Altered Intercellular Communication | This study investigated the importance of neutrophil/lymphocyte ratio (NLR) and other new inflammatory markers including CD64 expression in patients with chronic obstructive pulmonary disease (COPD) for identifying the severity of inflammation and recognition of acute exacerbation and infection. | 28185443 |
| ARCN1 gene, Inflammation | Altered Intercellular Communication | Elevated NLR can be used as a marker similar to CRP, and RDW, in the determination of increased inflammation in acutely exacerbated COPD. | 28185443 |
| Pneumonitis, CTCAE, Inflammation | Altered Intercellular Communication | Fluorodeoxyglucose PET/CT scanning can reveal inflammation secondary to pneumonitis but is not sufficiently specific for diagnosis. | 28185527 |
| Disorder of the optic nerve, Orbital Pseudotumor | Altered Intercellular Communication | The patients had a Mourits' score greater than three after treatment with corticosteroids and/or a severe NOSPECS score and/or orbital inflammation resistant to maximal treatment with intravenous injections of methylprednisolone and an optic neuropathy. | 28185649 |
| Inflammation, Hemorrhage, Traumatic injury | Altered Intercellular Communication | A number of pathophysiological descriptions involving aberrant angiogenic responses following trauma, hemorrhage, or inflammation have been proposed, although the exact etiology of these lesions remains to be elucidated. | 28186446 |
| Inflammation, Malnutrition | Altered Intercellular Communication | In models adjusted for iron dose, malnutrition and inflammation, mean ferritin levels increased over time in the overall cohort and across the three lower baseline ferritin strata. | 28186572 |
| Inflammation, Obesity | Altered Intercellular Communication | A direct link between development of insulin resistance and the presence of chronic inflammation, in case of obesity exists, with cytokines playing an important role in glucose metabolism. | 28186649 |
| Inflammation | Altered Intercellular Communication | However, local inflammation may result and can contribute to worsening of clinical status in these patients. | 28186686 |
| Osteosclerosis, Fracture, Inflammation, Osteolysis | Altered Intercellular Communication | We investigated the CT and dental panoramic radiograph (DPR) images for osteolysis, osteosclerosis, sequestration, periosteal reaction, pathological fracture and spread of soft tissue inflammation around the jaws. | 28186845 |
| Osteosclerosis, Inflammation, Osteolysis | Altered Intercellular Communication | Osteolysis, osteosclerosis, sequestration and spread of soft tissue inflammation around the jaws were common radiological features in both BRONJ and ORN. | 28186845 |
| Osteosclerosis, Inflammation, Osteolysis | Altered Intercellular Communication | Osteolysis and spreading of soft tissue inflammation around the jaws were predominant in ORN, and by contrast osteosclerosis was predominant in BRONJ. | 28186845 |
| Inflammation, Osteolysis | Altered Intercellular Communication | Image findings of BRONJ were characterized as a severe sclerotic change combined with osteolysis, sequestration, periosteal reaction and spread of soft tissue inflammation around the jaws. | 28186845 |
| Inflammation, Prosopagnosia | Altered Intercellular Communication | Tumoral Presentation of Homonymous Hemianopia and Prosopagnosia in Cerebral Amyloid Angiopathy-Related Inflammation. | 28187081 |
| Cerebral Amyloid Angiopathy, Inflammation | Altered Intercellular Communication | Found to have cerebral amyloid angiopathy-related inflammation proven by brain biopsy, she was treated successfully with immunosuppression. | 28187081 |
| Refractory anemias, Inflammation | Altered Intercellular Communication | Concentrations of small LDL (LDL-P) and HDL (HDL-P) particles are also reduced with increased inflammation and disease activity in RA patients. | 28187765 |
| Inflammation | Altered Intercellular Communication | Here we sought to identify which measure(s) of inflammation, disease activity and cardiometabolic risk contribute most to the RA-associated lipoprotein profile. | 28187765 |
| Refractory anemias, Pain Distress Question, Inflammation | Altered Intercellular Communication | Among RA patients, relationships were determined for lipoprotein parameters with measures of disease activity, disability, pain, inflammation, body composition, insulin sensitivity and exercise. | 28187765 |
| Endothelial dysfunction | Altered Intercellular Communication | Inflammation-induced caveolin-1 and BMPRII depletion promotes endothelial dysfunction and TGF-b-driven pulmonary vascular remodeling. | 28188225 |
| Granulomatous inflammation | Altered Intercellular Communication | * Pathological diagnosis of granulomatous inflammation is a robust indicator for 'true-negatives'. | 28188426 |
| Ascites | Altered Intercellular Communication | The glycome of ascites shows typical features of inflammatory conditions, what was also found in the serum of patients suffering from EOC when compared to healthy serum. | 28188862 |
| Inflammation, Milk, Human | Altered Intercellular Communication | Based on the role of calprotectin in inflammation, its higher levels in exclusively breastfed infants is contrary to breast milk benefits and may be a sign of enhanced mucosal immune maturity in them. | 28188944 |
| Degenerative polyarthritis, Inflammation | Altered Intercellular Communication | The role of inflammation in the pathogenesis of osteoarthritis is being given major interest, and inflammation is closely linked with vascularization. | 28189197 |
| Inflammation, Coronary Artery Disease, Atherosclerosis, Coronary Thrombosis | Altered Intercellular Communication | Inflammation plays an important role in atherosclerosis formation, coronary artery disease progression, acute coronary thrombosis and occlusion. | 28189264 |
| Vascular System Injuries | Altered Intercellular Communication | Chemokines are inflammatory mediators disposing several bio-functions, as leukocyte migration towards inflammatory signals and vascular injuries. | 28189264 |
| Lichen Planus | Altered Intercellular Communication | Increased melatonin in oral mucosal tissue of oral lichen planus (OLP) patients: A possible link between melatonin and its role in oral mucosal inflammation. | 28189880 |
| Inflammation | Altered Intercellular Communication | Increased levels of AANAT, melatonin, and MT1 in the inflamed oral mucosal tissue of OLP patients imply that chronic inflammation may induce the local biosynthesis of melatonin via AANAT, and may enhance the action of melatonin via MT1. | 28189880 |
| Inflammation, Blood Vessel, Antihypertensive Agents | Altered Intercellular Communication | We investigated whether Southern Italy resistant hypertensives presented an association between the presence of I and/or D alleles and early vascular damage, inflammation, and insulin resistance. | 28190172 |
| Inflammation, ETV3 wt Allele | Altered Intercellular Communication | DD genotype appeared to be associated with AS and HOMA index, but not with inflammation, independently from blood pressure values and the presence of other MetS factors, confirming D allele as an independent risk marker. | 28190172 |
| ARCN1 gene, Inflammation | Altered Intercellular Communication | Overall, chronic inflammation may expand sub-populations of T cells expressing CTLA-4 in COPD patients and therefore impair T-cell function. | 28190271 |
| Hyperpyrexia | Altered Intercellular Communication | Glutamate is an excitatory neurotransmitter that is utilized by the organum vasculosum laminae terminalis through the neuronal excitatory system and causes an increase in body temperature which can lead to hyperpyrexia. | 28190402 |
| Inflammation, Cardiovascular morbidity | Altered Intercellular Communication | Systemic inflammation biomarkers have been associated with risk of cardiovascular morbidity and mortality. | 28190687 |
| Inflammation, Primary malignant neoplasm, Allergy - Charge Type Reason, Autoimmune Diseases, Immune System Diseases | Altered Intercellular Communication | It is known that PIDs can also predispose to cancer and immune diseases, including allergy, autoimmunity, and inflammation. | 28192146 |
| Autoimmune Diseases, Inflammation | Altered Intercellular Communication | We aimed at determining the incidence of autoimmunity and inflammation in patients with PIDs. | 28192146 |
| MTA2 gene, Inflammation, Autoimmune Diseases | Altered Intercellular Communication | We have retrospectively screened 2183 consecutive cases of PID in the Centre de Reference Deficits Immunitaires Hereditaires registry (CEREDIH; the French national PID registry) for the occurrence of autoimmunity and inflammation. | 28192146 |
| Inflammation, Primary Biliary Cholangitis | Altered Intercellular Communication | In this study, four microRNAs were identified as being decreased in PBC patients, leading to activation of T cell receptor signalling pathways, involved in inflammation. | 28192189 |
| Craniocerebral Trauma, Hyperlipidemia, Primary malignant neoplasm, Malnutrition, Atrial Fibrillation by ECG Finding, Presenile dementia, Autoimmune Diseases, Diabetes Mellitus, Cerebrovascular accident, Congestive heart failure, Chronic Obstructive Airway Disease, Hepatobiliary Disorder, Coronary Artery Disease, Depression, CTCAE, Acute and chronic inflammation, Hypertension, CTCAE | Altered Intercellular Communication | A 1.88-fold increased risk of dementia (95% confidence interval, 1.76-2.01) was observed after adjustment for age, sex, and several comorbidities (diabetes, hypertension, hyperlipidemia, head injury, depression, stroke, chronic obstructive pulmonary disease, coronary artery disease, congestive heart failure, atrial fibrillation, cancer, liver disease, chronic infection/inflammation, autoimmune disease, malnutrition). | 28192452 |
| Cartilage destruction, Inflammation, Arthritis | Altered Intercellular Communication | In vivo, A77 1726 reduced the clinical arthritis severity of histological inflammation and cartilage destruction. | 28193225 |
| Arthritis, Autoimmune arthritis | Altered Intercellular Communication | The inhibitory effects of A77 1726 on joint inflammation and oxidative stress in autoimmune arthritis may be associated with HO-1 induction in CD4+ T cells. | 28193225 |
| Inflammation, Bipolar Disorder, Breast Carcinoma, Fatigue | Altered Intercellular Communication | Depressive symptoms and inflammation are independent risk factors of fatigue in breast cancer survivors. | 28193310 |
| Inflammation, Bipolar Disorder, Dyssomnias, Fatigue | Altered Intercellular Communication | A post-hoc mediation model using PROCESS SPSS was conducted to examine the association among depressive symptoms, sleep problems, stress, inflammation and fatigue. | 28193310 |
| Primary malignant neoplasm | Altered Intercellular Communication | MicroRNA 301A Promotes Intestinal Inflammation and Colitis-Associated Cancer Development by Inhibiting BTG1. | 28193514 |
| Primary malignant neoplasm | Altered Intercellular Communication | Transforming growth factor (TGF)-b-activated kinase 1 (TAK1) is one of the major regulators of inflammation-induced cancer cell growth and progression. | 28194669 |
| Inflammation, AT-Hook Motifs, Atherosclerosis | Altered Intercellular Communication | Inflammation plays a pivotal role in the initiation and progression of atherosclerosis (ATH). | 28194905 |
| Neoplasms | Altered Intercellular Communication | High CR expression was associated with tumors of high grade (P < 0.0001), high locoregional recurrence (P = 0.005), hormonal receptors negative, and high Ki-67 indices. | 28195084 |
| Inflammation, neuropeptide hormone activity | Altered Intercellular Communication | Our main findings were: (i) Compared to controls, patients with HF had significantly increased levels of factor D and TCC, and decreased levels of properdin, particularly patients with advanced clinical disorder (i.e., NYHA functional class IV), (ii) Levels of factor D and properdin in HF patients were correlated with measures of systemic inflammation (i.e., C-reactive protein), neurohormonal deterioration (i.e., Nt-proBNP), cardiac function, and deteriorated diastolic function, (iii) Low levels of factor H and properdin were associated with adverse outcome in univariate analysis and for factor H, this was also seen in an adjusted model. | 28195242 |
| Inflammation, Fibrosis Assessment | Altered Intercellular Communication | Analysis of the histologic features showed that the concomitant presence of inflammation, nerve bundles, and fibrosis (often mild) is prevalent in VD. | 28195255 |
| Inflammation, Fibrosis Assessment, Federated States of Micronesia | Altered Intercellular Communication | Fibrosis is highly frequent and often moderate/severe in FM and it is rarely associated to inflammation and nerve bundles. | 28195255 |
| vascular inflammations | Altered Intercellular Communication | Low salivary resolvin D1 to leukotriene B4 ratio predicts carotid intima media thickness: A novel biomarker of non-resolving vascular inflammation. | 28195518 |
| vascular inflammations | Altered Intercellular Communication | Background Different lipid mediators may have opposing effects on vascular inflammation. | 28195518 |
| Inflammation, Cardiovascular Diseases | Altered Intercellular Communication | Conclusions The ratio between the proresolving and proinflammatory salivary lipid mediators RvD1 and LTB4 may serve as a biomarker of non-resolving inflammation and its relation to intima media thickness in cardiovascular disease. | 28195518 |
| Lymphoma, Chronic inflammation, Neoplasms | Altered Intercellular Communication | Fibrin-associated EBV-positive Large B-Cell Lymphoma: An Indolent Neoplasm With Features Distinct From Diffuse Large B-Cell Lymphoma Associated With Chronic Inflammation. | 28195879 |
| Inflammation | Altered Intercellular Communication | Incidental cases of localized fibrin-associated Epstein-Barr virus (EBV)+ large B-cell proliferations have been described at unusual anatomic sites and have been included in the category of diffuse large B-cell lymphoma associated with chronic inflammation (DLBCL-CI) in the WHO Classification. | 28195879 |
| AURKAIP1 gene, Carcinogenesis | Altered Intercellular Communication | AIP's inflammatory condition may be related to carcinogenesis. | 28196014 |
| Inflammation, Myocarditis, CTCAE 5.0 | Altered Intercellular Communication | BACKGROUND Myocarditis, defined as inflammation of myocardial tissue of the heart, is an uncommon cardiac presentation and is due to a variety of causes. | 28196967 |
| Inflammation, Liver carcinoma, FAM126A gene | Altered Intercellular Communication | The Glasgow Prognostic Score (GPS), a simple assessment of systemic inflammation status, could be useful to predict the prognosis of hepatocellular carcinoma (HCC) patients after hepatectomy. | 28197709 |
| Non-necrotizing granulomatous inflammation | Altered Intercellular Communication | Lymph node biopsies revealed non-caseating granulomatous inflammation. | 28199763 |
| Inflammation, HIV | Altered Intercellular Communication | Genital inflammation is a key determinant of human immunodeficiency virus (HIV) transmission, and may increase HIV-susceptible target cells and alter epithelial integrity. | 28201724 |
| Inflammation | Altered Intercellular Communication | Chronic inflammation of the peritoneum causes peritoneal injury in patients on peritoneal dialysis. | 28201944 |
| Inflammation | Altered Intercellular Communication | Intercellular adhesion molecule-1 and its circulating form, soluble intercellular adhesion molecule-1, play pivotal roles in inflammation. | 28201944 |
| Inflammation, Cholangitis | Altered Intercellular Communication | The pathological report showed severe acute and chronic inflammation of the bile duct with morphology and immunohistochemistry suggestive of IgG4-related sclerosing cholangitis. | 28202062 |
| Inflammation, Asthma, Deep thrombophlebitis | Altered Intercellular Communication | Asthma was associated with an increased risk of PE, DVT and combined PE and DVT.Thus, the inflammation conferred by asthma seems to have systemic (and not just local) prothrombotic effects with increased risk of both DVT and PE. | 28202551 |
| Inflammation, Sleep Apnea, Obstructive, Metabolic Syndrome X | Altered Intercellular Communication | Concurrent presence of inflammation and obstructive sleep apnea exacerbates the risk of metabolic syndrome: A KoGES 6-year follow-up study. | 28207497 |
| Inflammation, Sleep Apnea, Obstructive, Osage language | Altered Intercellular Communication | Obstructive sleep apnea (OSA) leads to multiple end-organ morbidities that are mediated by the cumulative burden of oxidative stress and inflammation. | 28207497 |
| Inflammation, Osage language, Cyclophosphamide/Vincristine/Dacarbazine Regimen, Cardiovascular Diseases | Altered Intercellular Communication | Both OSA and inflammation play key roles in increased risk of cardiovascular disease (CVD). | 28207497 |
| Inflammation, Metabolic Syndrome X, ETV3 wt Allele, Osage language | Altered Intercellular Communication | Thus, we hypothesized that the combination of inflammation and OSA could accelerate the development of metabolic syndrome (MetS) in a large cohort study.A total of 1835 participants were randomly selected from the ongoing Korean Genome and Epidemiology Study for the years between 2007 and 2015. | 28207497 |
| Inflammation, ETV3 wt Allele, Osage language | Altered Intercellular Communication | The incidence of MetS among the 4 groups stratified by OSA and inflammation status at the 6-year follow-up was 11.8%, 19.9%, 25.8%, and 36.0% (HsCRP[-]/OSA[-] vs HsCRP[+]/OSA[-] vs HsCRP[-]/OSA[+] vs HsCRP[+]/OSA[+], P < 0.01). | 28207497 |
| Inflammation, ETV3 wt Allele, Osage language | Altered Intercellular Communication | Additional research is needed to help further define the significance of the combined effect of OSA and subclinical inflammation on the development of MetS in the context of reduction of CVD risk. | 28207497 |
| Inflammation, Spinal Cord Injuries, Traumatic, Cardiac Arrest, Communicable Diseases, Cerebrovascular accident, Status Epilepticus, Hydrocephalus | Altered Intercellular Communication | Children 7 days to 17 years old admitted to the ICU with new traumatic brain injury, stroke, cardiac arrest, CNS infection or inflammation, status epilepticus, spinal cord injury, hydrocephalus, or brain mass. | 28207570 |
| Cardiac Arrest, Inflammation | Altered Intercellular Communication | The most common neurologic insult was infection/inflammation in South America, Asia, and the single African site but cardiac arrest in the remaining regions. | 28207570 |
| Inflammation, Overweight, Chronic disease | Altered Intercellular Communication | This study examined the effects of an encapsulated fruit and vegetable (F&V) juice concentrate on systemic inflammation and other risk factors for chronic disease in overweight and obese adults. | 28208713 |
| Inflammation | Altered Intercellular Communication | Therefore, F&V juice concentrate improves the metabolic profile, by reducing systemic inflammation and blood lipid profiles and, thus, may be useful in reducing the risk of obesity-induced chronic disease. | 28208713 |
| Inflammation, Primary malignant neoplasm, Cachexia, Neoplasms | Altered Intercellular Communication | A high neutrophil/lymphocyte ratio (NLR) at baseline and at follow-up is associated with shorter survival in cancer patients and may be a surrogate for ongoing inflammation, implicated in cancer cachexia and tumor progression. | 28209123 |
| Non-Small Cell Lung Carcinoma, Cachexia, Neoplasms | Altered Intercellular Communication | In addition to having prognostic significance, these observations suggest that studying molecular mediators of cachexia/inflammation and their relationships to tumor progression may identify new therapeutic targets in the large subset of NSCLC patients who have cancer cachexia. | 28209123 |
| Inflammation, Lip and Oral Cavity Carcinoma | Altered Intercellular Communication | C-reactive protein (CRP) is an early marker for inflammation, and a relationship between serum CRP levels and survival in oral cancer has been demonstrated previously. | 28209200 |
| Hypernatremia, Inflammation | Altered Intercellular Communication | In hemodialysis patients extracellular fluid overload is a predictor of all-cause and cardiovascular mortality, and a relation with inflammation has been reported in previous studies. | 28209335 |
| Hypernatremia, Inflammation, Cessation of life | Altered Intercellular Communication | The concurrent presence of fluid overload and inflammation was associated with the highest risk of death. | 28209335 |
| Hypernatremia, Inflammation | Altered Intercellular Communication | Thus, while pre-dialysis fluid overload was associated with inflammation, even in the absence of inflammation, fluid overload remained a significant risk factor for short-term mortality, even following improvement of fluid status. | 28209335 |
| Airway structure, Asthma | Altered Intercellular Communication | Blood eosinophil count is a marker of eosinophilic airway inflammation and disease severity in asthma. | 28209625 |
| Communicable Diseases, Inflammation, Traumatic injury, Neoplasms | Altered Intercellular Communication | Trauma, infection, inflammation, neoplasia, and mechanical obstruction are secondary one. | 28210015 |
| Inflammation, Periodontitis, Bacterial Infections | Altered Intercellular Communication | Due to its potential to influence systemic inflammation and oxidative stress, and to predispose to bacterial infections, sleep duration could potentially be a risk factor for periodontitis. | 28211083 |
| Inflammation | Altered Intercellular Communication | In particular, increased levels of inflammation markers as well as DNA damage are observed. | 28211642 |
| Inflammation | Altered Intercellular Communication | Pharmacological intervention reverses the strain-induced damage by shifting gene expression profile away from inflammation. | 28211642 |
| Loss of myelin, Inflammation, Blood Vessel | Altered Intercellular Communication | Deep frontal white matter showed increased gliosis in HIV+ subjects vs. HIV- controls (p = 0.09), but no significant differences in myelin loss, blood vessel thickening, or inflammation. | 28212619 |
| Inflammation, Fatty degeneration | Altered Intercellular Communication | Liver showed more severe fibrosis/cirrhosis (p = 0.02) and less steatosis (p = 0.03) in HIV+ subjects, but no significant differences in inflammation, blood vessel thickness, or pigment deposition. | 28212619 |
| Inflammation, Coronary Artery Disease | Altered Intercellular Communication | Inflammation is a key process underlying the clinical course of coronary artery disease (CAD). | 28212870 |
| Degenerative polyarthritis, Inflammation | Altered Intercellular Communication | Osteoarthritis (OA) is a degenerative joint disease characterized by cartilage degradation and inflammation. | 28213268 |
| Fragile X Syndrome | Altered Intercellular Communication | The behavioral and anatomical deficits seen in fragile X syndrome (FXS) are widely believed to result from imbalances in the relative strengths of excitatory and inhibitory neurotransmission. | 28213518 |
| Deficit, Fragile X Syndrome | Altered Intercellular Communication | Significantly, this deficit contributes to the pathophysiology of FXS as the GABABR agonist (R)-baclofen rescued the imbalances between excitatory and inhibitory neurotransmission evident in Fmr1-KO mice. | 28213518 |
| Inflammation, Demyelination, MS gene, Pathology | Altered Intercellular Communication | The presence of inflammation and demyelination in a central nervous system (CNS) biopsy points towards a limited, yet heterogeneous group of pathologies, of which multiple sclerosis (MS) represents one of the principal considerations. | 28213912 |
| Inflammation, Have Autoimmune or Inflammatory Condition | Altered Intercellular Communication | Our data indicate that in the presence of extensive inflammation and incomplete, inhomogeneous demyelination, the neuropathologist should refrain from primarily considering autoimmune inflammatory demyelination and, even in the absence of lymphoma cells, instigate close clinical follow-up of the patient to detect recurrent lymphoma. | 28213912 |
| Vasculitis, Heart failure | Altered Intercellular Communication | Comorbidity-driven microvascular inflammation is postulated to play a key role in heart failure with preserved ejection fraction (HFpEF) pathophysiology, but data on how sST2 relates to clinical characteristics or inflammatory conditions or biomarkers in HFpEF are limited. | 28214792 |
| Inflammation, Fibrosis Assessment, Myocardial Infarction | Altered Intercellular Communication | Clinical characteristics; cardiac structure and function; exercise performance; and biomarkers of neurohumoral activation, systemic inflammation and fibrosis, and myocardial necrosis were assessed in relation to sST2 levels. | 28214792 |
| Inflammation, Atrial Fibrillation by ECG Finding, Fibrosis Assessment, Myocardial Infarction, Diabetes Mellitus, Tissue Congestion, physiopathological, Impaired exercise tolerance, Renal Insufficiency | Altered Intercellular Communication | Among HFpEF patients, higher sST2 levels were associated with the presence of diabetes mellitus; atrial fibrillation; renal dysfunction; right ventricular pressure overload and dysfunction; systemic congestion; exercise intolerance; and biomarkers of systemic inflammation and fibrosis, neurohumoral activation, and myocardial necrosis (P<0.05 for all). | 28214792 |
| Inflammation | Altered Intercellular Communication | These data suggest that ST2 may be a marker of systemic inflammation in HFpEF and potentially of extracardiac origin. | 28214792 |
| Vasculitis, Heart failure | Altered Intercellular Communication | Comorbidity-driven microvascular inflammation is postulated to play a key role in heart failure with preserved ejection fraction (HFpEF) pathophysiology, but data on how sST2 relates to clinical characteristics or inflammatory conditions or biomarkers in HFpEF are limited. | 28214792 |
| Inflammation, Fatty degeneration, Non-alcoholic Fatty Liver Disease, Liver damage, Obesity | Altered Intercellular Communication | The incidence of nonalcoholic fatty liver disease (NAFLD), ranging from mild steatosis to hepatocellular injury and inflammation, increases with the rise of obesity. | 28214827 |
| Cessation of life, Inflammation, Fever, CTCAE | Altered Intercellular Communication | Eryptosis, the suicidal erythrocyte death characterized by cell shrinkage and phosphatidylserine-translocation, is triggered by fever and inflammation. | 28214863 |
| Communicable Diseases, Inflammation, Collagen Diseases | Altered Intercellular Communication | Urinary free light chains may help to identify infection in patients with elevated systemic inflammation due to rheumatic disease. | 28214923 |
| Communicable Diseases, Inflammation, Rheumatism | Altered Intercellular Communication | The risk of infection in patients with rheumatic diseases is elevated, but a clear marker to differentiate the cause of the systemic inflammation is missing. | 28214923 |
| Communicable Diseases, Inflammation, Collagen Diseases | Altered Intercellular Communication | Of the 382 patients with rheumatic disease, 172 (45%) displayed no systemic inflammation, 162 (42%) had inflammation due to the underlying disease activity, and 48 (13%) had inflammation due to a confirmed infection. | 28214923 |
| Communicable Diseases, Inflammation, Rheumatism, Collagen Diseases | Altered Intercellular Communication | Urinary FLC concentrations were much higher in patients with rheumatic diseases and infection (k 68.8 +- 81.8 mg/L, l 31.4 +- 53.5 mg/L) compared to those with inflammation due to rheumatic disease activity (k 22.7 +- 26.3 mg/L, l 8.1 +- 9.1 mg/L, k p < 0.001, l p = 0.004). | 28214923 |
| Communicable Diseases, Inflammation, Collagen Diseases | Altered Intercellular Communication | FLCs may be useful for distinguishing inflammation due to rheumatic disease activity from that due to the additional presence of infection. | 28214923 |
| Inflammatory Bowel Diseases, Inflammation, MS gene | Altered Intercellular Communication | Fibronectin connecting segment-1 (FNCS1), an alternatively spliced fibronectin variant expressed by microvascular endothelial cells at sites of inflammation in vitro and in situ, is a counterligand for leukocyte a4 integrin (also known as CD49d) implicated in pathogenic leukocyte trafficking in multiple sclerosis and inflammatory bowel disease. | 28215575 |
| Inflammation | Altered Intercellular Communication | Additionally, extensor tendon inflammation (ETI) (0-3) was scored. | 28216312 |
| Airway structure | Altered Intercellular Communication | Extracellular eosinophilic traps in association with Staphylococcus aureus at the site of epithelial barrier defects in patients with severe airway inflammation. | 28216437 |
| Inflammation, Nasal Polyps, Chronic sinusitis | Altered Intercellular Communication | Chronic rhinosinusitis with nasal polyps is characterized by TH2-biased eosinophilic inflammation. | 28216437 |
| Inflammation, Cardiovascular Diseases | Altered Intercellular Communication | These results support the role of complement-dependent inflammation in the pathophysiology of cardiovascular disease. | 28216633 |
| Nonalcoholic Steatohepatitis, Inflammation, Fibrosis Assessment, Fatty degeneration, Non-alcoholic Fatty Liver Disease, Fatty Liver Disease | Altered Intercellular Communication | Serum LBP concentration was significantly increased in nonalcoholic steatohepatitis (NASH) patients as compared with nonalcoholic fatty liver (NAFL) subjects and was correlated with steatosis (r = 0.38, P < 0.0001) and ballooning scores (r = 0.23, P = 0.01), but not with the severity of lobular inflammation or fibrosis. | 28216979 |
| Inflammation, Fibrosis Assessment | Altered Intercellular Communication | LBP/EndoCab IgG were not correlated with lobular inflammation or fibrosis. | 28216979 |
| Myocarditis | Altered Intercellular Communication | The mechanisms underlying the disease process have not been precisely identified, but recent evidence has suggested that the activation of myocardial inflammation is involved in the deterioration associated with the condition. | 28217949 |
| Inflammation, Carcinogenesis | Altered Intercellular Communication | Inflammation plays a major role in colon carcinogenesis. | 28218420 |
| Inflammation, Carcinogenesis | Altered Intercellular Communication | Endogenously produced specialized proresolving lipid mediators (SPMs) play a central role in inflammation and tissue homeostasis, and have been implicated in carcinogenesis. | 28218420 |
| Inflammation, Cardiovascular Diseases | Altered Intercellular Communication | Defensive coping (DefS), oxidative stress, inflammation, and related amino acids (phenylalanine [Phe] and tyrosine [Tyr]) have been implicated in cardiovascular disease. | 28218795 |
| Inflammation, Obesity, Abdominal, Alcohol abuse | Altered Intercellular Communication | African men had poorer health than Caucasian men, including higher alcohol abuse, elevated BP, abdominal obesity, physical inactivity, and elevated inflammation. | 28218795 |
| Inflammation, Abnormality of the vasculature | Altered Intercellular Communication | African males presented with elevated Phe and Phe/Tyr ratio, catecholamine precursors, worsening during DefS-possibly driven by inflammation and BP contributing to structural vascular abnormalities. | 28218795 |
| Inflammation, Cervical Intraepithelial Neoplasia | Altered Intercellular Communication | In conclusion, ATIII appears to attenuate CIN through inhibiting inflammation, oxidative stress, apoptosis and improving renal blood flow. | 28219627 |
| Inflammation, Pruritus | Altered Intercellular Communication | Substance P (SP) is linked to itch and inflammation through activation of receptors on mast cells and sensory neurons. | 28219706 |
| Inflammation, Pruritus | Altered Intercellular Communication | Because Mrgprs mediate some aspects of inflammation that had been considered mediated by neurokinin-1 receptor (NK-1R), we sought to determine whether itch induced by SP can also be mediated by Mrgprs. | 28219706 |
| Inflammation, Atherosclerosis | Altered Intercellular Communication | DKK3 expression in macrophages is involved in the pathogenesis of atherosclerosis through modulation of inflammation and inactivation of the Wnt/b-catenin pathway. | 28219919 |
| Inflammation, Tissue Adhesions | Altered Intercellular Communication | In certain situations visualization of the Callot triangle can become difficult due to inflammation, adhesions, and sclerosing of the anatomy. | 28220035 |
| Neuromuscular Junction Diseases, Myasthenic Syndromes, Congenital, CD2AP gene | Altered Intercellular Communication | Congenital myasthenic syndromes (CMS) are a heterogeneous group of diseases of the neuromuscular junction caused by compromised synaptic transmission. | 28221305 |
| Inflammation | Altered Intercellular Communication | There was no inflammation or ciliary body detachment. | 28221333 |
| Inflammation, Pain Distress Question | Altered Intercellular Communication | The infrapatellar fat pad (IPFP) represents intra-articular adipose tissue that may contribute to intra-articular inflammation and pain by secretion of proinflammatory cytokines. | 28222422 |
| Inflammation, MS gene | Altered Intercellular Communication | Increased cortical lesion load and intrathecal inflammation is associated with oligoclonal bands in multiple sclerosis patients: a combined CSF and MRI study. | 28222766 |
| Cerebral cortex, Inflammation, MS gene | Altered Intercellular Communication | Although IgG oligoclonal bands (OCBs) in the cerebrospinal fluid (CSF) are a frequent phenomenon in multiple sclerosis (MS) patients, their relationship with grey matter lesions, intrathecal/meningeal inflammation and clinical evolution has not been clarified yet. | 28222766 |
| Inflammation, Pancreatic Ductal Adenocarcinoma | Altered Intercellular Communication | There is strong evidence linking inflammation and the development of pancreatic ductal adenocarcinoma. | 28222855 |
| Inflammation | Altered Intercellular Communication | Performance of subjective global assessment and malnutrition inflammation score for monitoring the nutritional status of older adults on hemodialysis. | 28222963 |
| Inflammation, Reperfusion Injury | Altered Intercellular Communication | Monocyte chemotactic protein-1 (MCP-1; chemokine C-C ligand-2 [CCL-2]) is upregulated in ischemia-reperfusion injury and is a promising biomarker of inflammation in cardiac operations. | 28223055 |
| Inflammation, Fibrosis Assessment, Pneumonia, Interstitial, Granuloma | Altered Intercellular Communication | Patients with a fibrotic nonspecific interstitial pneumonia (f-NSIP) pattern, bronchiolocentric fibrosis (BF) pattern, or usual interstitial pneumonia (UIP) pattern had significantly worse transplant-free survival than did those with a cellular NSIP (c-NSIP) pattern or peribronchiolar inflammation with poorly formed granulomas (PI-PFG) pattern. | 28223152 |
| Inflammation, Adult Glioblastoma | Altered Intercellular Communication | Preoperative inflammation markers and IDH mutation status predict glioblastoma patient survival. | 28223536 |
| Inflammation, Neoplasms | Altered Intercellular Communication | Recent studies suggest that inflammation response biomarkers are prognostic indicators of solid tumor outcomes. | 28223536 |
| Epithelial ovarian cancer | Altered Intercellular Communication | Several parameters of preoperative complete blood count (CBC) and inflammation-associated blood cell markers derived from them have been reported to correlate with prognosis in patients with epithelial ovarian cancer (EOC), but their prognostic importance and optimal cutoffs are still needed be elucidated. | 28223716 |
| Inflammation, Fibrosis Assessment, Liver Stiffness | Altered Intercellular Communication | Liver stiffness (LS) with MRE was calculated by a radiologist, and inflammation grade and fibrosis stage in liver biopsy was assessed by a pathologist in a blinded fashion. | 28223730 |
| Inflammation, Fibrosis Assessment | Altered Intercellular Communication | There were no significant differences in distribution of fibrosis stage and inflammation grade between treated and untreated patient groups. | 28223730 |
| Inflammation, Acquired Immunodeficiency Syndrome, Frailty | Altered Intercellular Communication | Frailty and Circulating Markers of Inflammation in HIV+ and HIV- Men in the Multicenter AIDS Cohort Study. | 28225718 |
| Inflammation, Frailty | Altered Intercellular Communication | Frailty is associated with immune activation and inflammation in the elderly general population, but whether this is true in the younger HIV-infected (HIV+) population is not known. | 28225718 |
| Inflammation, Interferon-Related DNA Damage Resistance Gene Signature, Inflammatory disorder | Altered Intercellular Communication | Pentraxin 3 is proposed to be a marker of inflammation and cardiovascular risk, but its role in inflammatory rheumatic diseases (IRDs) is still uncertain. | 28225768 |
| Interferon-Related DNA Damage Resistance Gene Signature, Inflammation | Altered Intercellular Communication | Therefore, we wanted to examine if anti-rheumatic treatment reduced serum PTX3 (s-PTX3) levels in IRDs, and if s-PTX3 levels were related to other markers of inflammation and to endothelial function (EF). | 28225768 |
| Inflammation | Altered Intercellular Communication | Thus, s-PTX3 might reflect a persisting immune process, even a causal factor of inflammation, not inhibited by the standard anti-rheumatic treatment. | 28225768 |
| Inflammation, Atrial Fibrillation | Altered Intercellular Communication | A relation between inflammation and AF has been suggested by findings of increased inflammatory markers in AF patients. | 28225836 |
| Mitral Valve Insufficiency, Inflammation, Hypertension, CTCAE, Diabetes Mellitus | Altered Intercellular Communication | Immune cell infiltration of LA was related to the rhythm, but not to age, body size, LA size, mitral regurgitation grade, type of surgery, systemic markers of inflammation or presence of diabetes or hypertension. | 28225836 |
| Inflammation | Altered Intercellular Communication | Knowledge of these variants in T2DM might contribute to a better understanding of the role of inflammation in the etiology and progression of this disease. | 28225860 |
| Inflammatory Bowel Diseases, Crohn Disease, Inflammation, Ulcerative Colitis | Altered Intercellular Communication | Inflammatory bowel diseases (IBD), including Crohn's disease (CD) and ulcerative colitis (UC), are characterized by chronic inflammation of the intestine that can reduce the absorption of nutrients such as vitamin D and calcium. | 28225873 |
| Communicable Diseases, Inflammation | Altered Intercellular Communication | Due to inflammation, it may be difficult to diagnose infection when it occurs, but measurement of C-reactive protein could facilitate this diagnosis. | 28226029 |
| Malignant Peripheral Nerve Sheath Tumor, JAK2 NP_004963.1:p.V617F, Inflammation, Myeloproliferative disease | Altered Intercellular Communication | The driver mutations JAK2V617F, MPLW515L/K and CALR influence disease phenotype of myeloproliferative neoplasms (MPNs) and might sustain a condition of chronic inflammation. | 28228104 |
| JAK2 NP_004963.1:p.V617F, Inflammation | Altered Intercellular Communication | These results provide evidence that JAK2V617F mutation influences MPN-associated inflammation with a strong correlation between allele burden and PTX3 levels. | 28228104 |
| Inflammation, Endothelial dysfunction, Vascular Diseases | Altered Intercellular Communication | Endothelial dysfunction and inflammation are key mechanisms of vascular disease. | 28229168 |
| ACSM3 gene, Inflammation | Altered Intercellular Communication | This study showed an early increased sTREM-1 CSF level in SAH patients, which correlated with inflammation intensity post-SAH and clinical severity, indicating that TREM-1 may participate in the inflammatory mechanisms of EBI. | 28229304 |
| Inflammation, Atrial Fibrillation by ECG Finding | Altered Intercellular Communication | Routine 18F-FDG PET/CT does not detect inflammation in the left atrium in patients with atrial fibrillation. | 28229312 |
| Inflammation, Atrial Fibrillation, Atrial Fibrillation by ECG Finding | Altered Intercellular Communication | Increasing evidence supports a role of inflammation in the development of atrial fibrillation (AF). | 28229312 |
| Inflammation | Altered Intercellular Communication | Contrary to previous reports, these results therefore do not clearly support a role for ongoing atrial inflammation in patients with AF. | 28229312 |
| PROS1 gene, Arthritis, Psoriatic | Altered Intercellular Communication | Psoriatic arthritis (PsA) is a variable and complex inflammatory condition. | 28229377 |
| Inflammation | Altered Intercellular Communication | Honokiol protects skin cells against inflammation, collagenolysis, apoptosis, and senescence caused by cigarette smoke damage. | 28229451 |
| Inflammation | Altered Intercellular Communication | Honokiol protects both HFF-1 and HaCat against cigarette smoke-induced inflammation, collagenolysis, apoptosis, and senescence. | 28229451 |
| Inflammation | Altered Intercellular Communication | SHARPIN, SHANK-associated RH domain interacting protein, associates with a linear ubiquitin chain assembly complex (LUBAC) to regulate inflammation and immunity. | 28230260 |
| Cardiovascular system | Altered Intercellular Communication | Basigin (BSG) promotes cardiovascular inflammation and myocardial remodeling processes by induction of extracellular matrix metalloproteinases and inflammatory cytokines. | 28230811 |
| Airway structure | Altered Intercellular Communication | Asthma is characterized by a heterogeneous inflammatory profile and can be subdivided into T(h)2-high and T(h)2-low airway inflammation. | 28231834 |
| Inflammation, FBN2 wt Allele | Altered Intercellular Communication | Ov-associated CCA is the culmination of chronic Ov-infection, with the persistent production of the growth factors and cytokines associated with persistent inflammation, which can endure for years in Ov-infected individuals prior to transitioning to CCA. | 28232516 |
| Primary malignant neoplasm, FBN2 wt Allele | Altered Intercellular Communication | The profile of protein dysregulation observed during chronic Ovinfection and then in Ov-induced CCA provides insight into the etiology of an infection-induced inflammation-related cancer. | 28232516 |
| atherosclerotic | Altered Intercellular Communication | 18F-FDG is the most widely validated PET tracer for the evaluation of atherosclerotic inflammation. | 28232606 |
| Inflammation, Atherosclerosis | Altered Intercellular Communication | We aimed to analyze the association between inflammation and osteogenesis at different stages of atherosclerosis, as well as the interrelationship between these 2 processes during disease progression. | 28232606 |
| Inflammation, Atherosclerosis | Altered Intercellular Communication | The association between inflammation and osteogenesis during atherosclerosis progression was evaluated in 19 patients who had at least 2 examinations with both tracers. | 28232606 |
| vascular inflammations | Altered Intercellular Communication | Most noncalcified (86%) and mildly calcified (81%) lesions and 47% of severely calcified lesions had concordant development of both vascular inflammation and osteogenesis. | 28232606 |
| Communicable Diseases, Hemorrhage, Inflammation, Extravasation | Altered Intercellular Communication | Wound healing was achieved in all patients, with no case of wound infection, bleeding, leakage or inflammation. | 28233056 |
| Inflammation, Malnutrition, Edema, Fracture | Altered Intercellular Communication | In addition, (S) had higher state of inflammation (erythrocyte sedimentation rate: p < 0.05 and C-reactive protein: p < 0.01), and an increase of risk of fractures (FRAX: OR 1.07; p < 0.001), risk of malnutrition (mini nutritional assessment: p < 0.001), and risk of edema (extra cellular water: p < 0.001). | 28233283 |
| Inflammation, Sarcopenia, Malnutrition, Edema | Altered Intercellular Communication | Sarcopenia is closely linked to an increase in the risk of hip-femur fractures, inflammation, edema, and malnutrition. | 28233283 |
| Allergic sensitization, Sinusitis | Altered Intercellular Communication | Allergic sensitization does not predispose to sinus inflammation in externalized paranasal sinuses. | 28234140 |
| Inflammation, Hypersensitivity, Neoplasms | Altered Intercellular Communication | Externalization of the sinuses in patients with inhalant allergy did not bring about significant additional inflammation in patients after tumor surgery. | 28234140 |
| Inflammation, MS4A2 wt Allele | Altered Intercellular Communication | The patients with CRSwNP and with atopy but not the patients with CRSsNP and with atopy demonstrated systemic eosinophilic inflammation. | 28234143 |
| Inflammation, Adenolymphoma | Altered Intercellular Communication | Inflammation following invasive procedures for Warthin's tumour: A retrospective case series. | 28235157 |
| Inflammation, Adenolymphoma | Altered Intercellular Communication | To determine the risk of inflammation associated with fine-needle aspiration during evaluation of Warthin's tumour. | 28235157 |
| Parotid Neoplasms, Adenolymphoma, Inflammation | Altered Intercellular Communication | Warthin's tumour is associated with a tenfold higher risk of inflammation compared to other parotid tumours following invasive procedures. | 28235157 |
| Inflammation, Depression, CTCAE | Altered Intercellular Communication | The association between DGLA and depression was not dependent on inflammation (P-interaction=0.618). | 28235735 |
| Inflammation, Calcified (qualifier) | Altered Intercellular Communication | The side-specific progression of the disease is characterized by inflammation, calcific lesions, and extracellular matrix (ECM) degradation. | 28236165 |
| Inflammation, Toxic effect | Altered Intercellular Communication | Neither toxicity nor inflammation from RGD.Flt23k.NP was detected. | 28236576 |
| PEX19 gene, Inflammation, Zonular dehiscence | Altered Intercellular Communication | The following complications occurred more frequently in PXF cases: zonular dehiscence without vitrectomy (4 [3.3%] PXF cases vs 40 [0.8%] non-PXF cases p = 0.02), persistent inflammation (28 [24.1%] vs 668 [14.5%]; p = 0.007), and persistent intraocular pressure elevation (5 [4.3%] vs 68 [1.5%]; p = 0.03). | 28237151 |
| PROS1 gene, Inflammation, Arthritis, Psoriatic, Psoriasis | Altered Intercellular Communication | The factors that contribute to the development of psoriatic arthritis (PsA) among patients with psoriasis are not well known; however, systemic inflammation is believed to be important. | 28237512 |
| Minimal Disseminated Disease, Depressive disorder, Inflammation, Psoriasis | Altered Intercellular Communication | On the basis of recent laboratory work demonstrating that major depressive disorder (MDD) is associated with increased systemic inflammation, we hypothesized that patients with psoriasis who develop MDD are at increased risk of subsequently developing PsA. | 28237512 |
| Schizophrenia | Altered Intercellular Communication | Chronic low-grade peripheral inflammation is associated with severe nicotine dependence in schizophrenia: results from the national multicentric FACE-SZ cohort. | 28238173 |
| Seizures, Inflammation, Impaired cognition, Schizophrenia | Altered Intercellular Communication | Chronic peripheral inflammation (CPI) has been associated with cognitive impairment in schizophrenia (SZ). | 28238173 |
| Chronic hemolytic anemia, Inflammation, SLC22A5 gene | Altered Intercellular Communication | Manifestations of SCD include chronic hemolytic anemia, inflammation, painful vaso-occlusive crises, multisystem organ damage, and reduced life expectancy. | 28238805 |
| Inflammation, Malignant Neoplasms | Altered Intercellular Communication | The initial mucosal biopsy finding was chronic inflammation, but we were highly suspicion of malignancy; we performed an endoscopic mucosal resection. | 28239083 |
| Ulcerative Colitis, Inflammatory disease of mucous membrane | Altered Intercellular Communication | To optimise treatment of ulcerative colitis (UC), patients need repeated assessment of mucosal inflammation. | 28239876 |
| Inflammation, Ulcerative Colitis | Altered Intercellular Communication | VOCs have demonstrated potential as new non-invasive biomarker to monitor inflammation in UC. | 28239876 |
| Inflammation, Fasciitis, Contracture, Polyarthritis | Altered Intercellular Communication | Palmar fasciitis and polyarthritis syndrome (PFPAS) is an uncommon disorder characterized by diffuse inflammation of the palmar fascia, tendon sheaths, and joints of the fingers and wrists, which rapidly progresses to flexion contracture of the hands. | 28239882 |
| palladium, Inflammation | Altered Intercellular Communication | Our study indicates a state of systemic inflammation and oxidative stress in PD patients coupled with alterations in Fe metabolism. | 28240188 |
| palladium, Inflammation | Altered Intercellular Communication | Chronic inflammation and oxidative pathways in PD may in part determine changes in iron metabolism. | 28240188 |
| Endothelial dysfunction | Altered Intercellular Communication | In conclusion, as GFR declines Cat-S and markers of inflammation-related endothelial dysfunction increase. | 28240259 |
| Chronobiology Disorders, Migraine with Aura, physiopathological | Altered Intercellular Communication | The neurological disturbances of migraine aura are caused by transient cortical dysfunction due to waves of spreading depolarization that disrupt neuronal signaling. | 28240389 |
| Respiratory Distress Syndrome, Adult, Pneumonitis | Altered Intercellular Communication | Early treatment with inhaled corticosteroids and beta agonists may reduce progression to acute respiratory distress syndrome by reducing lung inflammation and enhancing alveolar fluid clearance. | 28240689 |
| Inflammation, Fibrosis Assessment, Heart failure | Altered Intercellular Communication | Galectin-3, a novel binding-lectin involved in inflammation and fibrosis, is elevated in heart failure and is independently predictive of mortality in this condition. | 28242288 |
| Communicable Diseases, Inflammation | Altered Intercellular Communication | The surgical exploration revealed no signs of inflammation or infection and excluded any endoleak, confirming the term "endotension". | 28242401 |
| ARCN1 gene, Inflammation | Altered Intercellular Communication | The major characteristic of COPD is systemic inflammation. | 28243079 |
| Inflammation, Non-alcoholic Fatty Liver Disease | Altered Intercellular Communication | Obesity increases the risk for non-alcoholic fatty liver disease through adipokine dysregulation and inflammation. | 28244519 |
| Inflammation | Altered Intercellular Communication | It plays a central role in many biological processes, including protein folding, host-pathogen interactions, immune response, and inflammation. | 28244758 |
| ARCN1 gene, Inflammation | Altered Intercellular Communication | This association was maintained after additionally adjusting for baseline CVD risk, for co-morbidities and descriptors of COPD severity and impact, markers of cardiac stress (N-terminal pro-B-type natriuretic peptide, troponin T) and of inflammation (Interleukin-6), and in subgroup analysis excluding men, diabetics, current smokers or those with limited ambulation. | 28245821 |
| Inflammation, Sample Size Calculation, Epstein-Barr Virus Infections | Altered Intercellular Communication | Immunogenicity of infectious EBV suggests a novel mechanism mediating monocyte inflammation in SSc, by which EBV triggers the innate immune response in infected cells. | 28245863 |
| Inflammation, Metabolic Diseases | Altered Intercellular Communication | Assessment of the comprehensive relationship among apolipoprotein CIII (apoCIII) levels, inflammation, and metabolic disorders is rare. | 28245894 |
| Inflammation, Metabolic Syndrome X, ETV3 wt Allele | Altered Intercellular Communication | A mediation analysis was used to detect the underlying role of apoCIII in the association of inflammation with metabolic syndrome (MetS). | 28245894 |
| Inflammation | Altered Intercellular Communication | To collaborate in the understanding of the biochemical mechanisms involved in the synovial inflammation process. | 28245911 |
| Inflammation, Malignant Neoplasms, Cerebrovascular accident | Altered Intercellular Communication | Our analysis suggests that a multiple algorithm combining the number of territories involved and laboratory signs of inflammation and cell turnover might identify patients with stroke suffering from previously unknown malignancy. | 28247043 |
| Inflammation, Respiratory Distress Syndrome, Newborn | Altered Intercellular Communication | Incorporating Inflammation into Mortality Risk in Pediatric Acute Respiratory Distress Syndrome. | 28248715 |
| Inflammation, Lung Injury, Respiratory Distress Syndrome, Newborn | Altered Intercellular Communication | In pediatric acute respiratory distress syndrome, lung injury is mediated by immune activation and severe inflammation. | 28248715 |
| Inflammation, Liver damage | Altered Intercellular Communication | The Role of Inflammation in the Mechanisms of Bile Acid-Induced Liver Damage. | 28249287 |
| Inflammation, Primary malignant neoplasm | Altered Intercellular Communication | The role of inflammation has been established in cancer biology and the neutrophil to lymphocyte ratio postulated as a marker of systemic inflammatory response. | 28249912 |
| Inflammation, Metabolic Syndrome X, Atherosclerosis | Altered Intercellular Communication | Semaphorin-3E, provoking inflammation and insulin resistance which leads to metabolic syndrome, exerts obscure effects on carotid atherosclerosis in metabolic syndrome. | 28249916 |
| Inflammation, Primary malignant neoplasm | Altered Intercellular Communication | Although many studies have examined the role of chronic inflammation in cancer development, few studies discuss the patterns of acute inflammation prior to cancer diagnosis. | 28250427 |
| Inflammation, Postoperative Complications, Saint Lucia | Altered Intercellular Communication | Patients with more severe inflammation according to Tokyo Criteria grade were more likely to undergo PC, were more likely to be readmitted while waiting for LC, and also had more postoperative complications. | 28251270 |
| allergic inflammation | Altered Intercellular Communication | Haemopoietic progenitor cells (HPC) migrate to sites of allergic inflammation where, upon stimulation with epithelial cytokines, they produce Th2 cytokines and differentiate into mature eosinophils and basophils. | 28252235 |
| Inflammation | Altered Intercellular Communication | Thus, implementation and maintenance of similar exercise programs can contribute to reduce chronic inflammation among obese postmenopausal women. | 28253046 |
| Inflammation, Fibrosis Assessment, Fatty degeneration, Fatty Liver Disease | Altered Intercellular Communication | Despite having more steatosis and inflammation, progression of fibrosis was slower in NASH compared with ALD recipients. | 28253211 |
| Diabetes Mellitus, Non-Insulin-Dependent | Altered Intercellular Communication | Our data suggest that luseogliflozin could reduce the EFV in parallel with the improvement of systemic micro-inflammation and the reduction of body weight in Japanese patients with type 2 diabetes. | 28253918 |
| Inflammation, Neurogenic arthropathy, Osteolysis | Altered Intercellular Communication | Persistent inflammation with pedal osteolysis 1year after Charcot neuropathic osteoarthropathy. | 28254346 |
| Inflammation, Neurogenic arthropathy, Peripheral Neuropathy, Diabetes Mellitus | Altered Intercellular Communication | To determine local and systemic markers of inflammation and bone mineral density (BMD) in the foot and central sites in participants with diabetes mellitus and peripheral neuropathy (DMPN) with and without acute Charcot neuropathic osteoarthropathy (CN). | 28254346 |
| Inflammation, Foot Deformities, Osteolysis | Altered Intercellular Communication | Local and systemic inflammation persists 1 year after CN with an accompanying pedal osteolysis that may contribute to mid foot deformity which is the hallmark of the chronic Charcot foot. | 28254346 |
| Electrocardiogram: myocardial infarction (finding) | Altered Intercellular Communication | Improvement of myocardial infarction risk prediction via inflammation-associated metabolite biomarkers. | 28255100 |
| Traumatic injury, Paralysed | Altered Intercellular Communication | Impaired expression of TLRs and HLA-DR in acute inflammatory conditions may be responsible for the well-described monocyte paralysis after severe trauma. | 28255201 |
| ARCN1 gene, Inflammation, Muscular Atrophy | Altered Intercellular Communication | Muscle wasting and chronic inflammation are predominant features of patients with COPD. | 28255238 |
| Inflammation | Altered Intercellular Communication | Systemic inflammation is associated with an accelerated decline in lung function. | 28255238 |
| ARCN1 gene, Inflammation, Sarcopenia | Altered Intercellular Communication | Systemic inflammation could be an important contributor to sarcopenia in the stable COPD population. | 28255238 |
| ARCN1 gene, Sarcopenia | Altered Intercellular Communication | In this study, the prevalence of sarcopenia and the relationships between sarcopenia and systemic inflammations in patients with stable COPD were investigated. | 28255238 |
| Inflammation, Diabetes Mellitus, Non-Insulin-Dependent, Cardiovascular Diseases | Altered Intercellular Communication | Systemic inflammation is involved in the development of several diseases, including cardiovascular disease and type 2 diabetes. | 28255731 |
| Coma, Post-Head Injury, Inflammation | Altered Intercellular Communication | Treatment of critical-sized, post-traumatic, acute wounds with OASIS resulted in decreased inflammation, and potentially more advanced wound healing, compared to SOC. | 28256051 |
| Autoimmune Diseases, Inflammation | Altered Intercellular Communication | These results, albeit preliminary and involving a small number of patients, are consistent with reports showing the presence of susceptibility loci within the HLA gene region for several inflammatory and autoimmune diseases, and with our previous findings indicating that the increased sensitivity to DOX cardiotoxicity was associated with dysregulation of genes implicated both in inflammation and autoimmune disorders. | 28256194 |
| Inflammation, Rheumatoid Arthritis | Altered Intercellular Communication | Its etiology and pathogenesis appear to be related to chronic inflammation in the affected area, prior surgery, or systemic disease, particularly rheumatoid arthritis. | 28256202 |
| Inflammation, Coronary Arteriosclerosis, atherosclerotic | Altered Intercellular Communication | Given the body of evidence implicating inflammation in atherosclerotic process, we hypothesized that procalcitonin (PCT) as an inflammatory marker may be related to coronary atherosclerotic burden. | 28256322 |
| Inflammation, Atherosclerosis | Altered Intercellular Communication | Treatment of local inflammation and reduction of systemic inflammatory markers are believed to lower the diagnostic criteria for atherosclerosis as well. | 28256493 |
| Giant Cell Arteritis, vascular inflammations | Altered Intercellular Communication | Although clinical signs and symptoms of giant cell arteritis improve promptly after starting glucocorticoid therapy, reports have suggested that the vascular inflammation may persist. | 28256573 |
| Granulomatous inflammation | Altered Intercellular Communication | Granulomatous inflammation decreased in a time-dependent manner from 78 to 100% at initial biopsy to 50% at 9 months and 25% at 12 months. | 28256573 |
| Inflammation, Secondary glaucoma, Lens Opacities | Altered Intercellular Communication | To report a case of conjunctival tattooing for cosmetic purposes with inadvertent globe penetration resulting in severe inflammation, capsular lens opacity, and secondary glaucoma. | 28257383 |
| Inflammatory abnormality of the eye | Altered Intercellular Communication | The patient underwent clinical and surgical treatments to control ocular inflammation and intraocular pressure. | 28257383 |
| Inflammation, Secondary glaucoma, Lens Opacities | Altered Intercellular Communication | An unusual case of conjunctival tattooing resulted in severe inflammation, capsular lens opacity, and secondary glaucoma. | 28257383 |
| Cardiac Arrest, Inflammation | Altered Intercellular Communication | Two mechanisms may explain that iron deposition largely spares the heart in SCA: the high level of erythropoiesis recycles the iron and the chronic inflammation retains iron within the macrophages. | 28257476 |
| Inflammation, Miller Dieker syndrome | Altered Intercellular Communication | Iron accumulation varies widely in MDS syndromes due to the competing influences of abnormal erythropoiesis, excess iron supply, and inflammation. | 28257476 |
| Antisynthetase syndrome, Arthritis, Lung Diseases, Interstitial, Myositis | Altered Intercellular Communication | Antisynthetase syndrome is a rare and debilitating multiorgan disease characterized by inflammatory myopathy, interstitial lung disease, cutaneous involvement, and frequent chronic inflammation of the joints. | 28257650 |
| Diabetes Mellitus | Altered Intercellular Communication | The association of vitamin D status and inflammation prediabetes mellitus (PreDM) individuals has not been investigated. | 28259644 |
| Inflammation, Impaired cognition, ETV3 wt Allele | Altered Intercellular Communication | This longitudinal study investigates whether MetS or its components affect cognitive decline in aging men and whether any interaction with inflammation exists. | 28259698 |
| Inflammation, Impaired cognition, ETV3 wt Allele | Altered Intercellular Communication | No evidence was found for a relationship between MetS or inflammation and cognitive decline in this sample of aging men. | 28259698 |
| Inflammation | Altered Intercellular Communication | Inflammation in the retinal pigment epithelium is an important contributor to the pathogenesis of age-related macular degeneration. | 28260013 |
| Inflammation, Aortic valve calcification, Congenital bilateral aplasia of vas deferens, Aortic valve disorder | Altered Intercellular Communication | Chronic inflammation and the calcification of aortic valve interstitial cells (AVICs) are the primary etiologies of calcific aortic valve disease (CAVD). | 28260034 |
| Inflammation, Calcinosis | Altered Intercellular Communication | The present study investigated the importance of high mobility group box 1 (HMGB1) via toll-like receptor 4 (TLR4) for the regulation of inflammation and calcification in AVICs. | 28260034 |
| Inflammation, Obesity | Altered Intercellular Communication | Obesity is associated with chronic, low grade, systemic inflammation. | 28260748 |
| Airway structure, Craniosynostosis | Altered Intercellular Communication | CRS was associated with COPD-Bx and this was probably due to increased airway inflammation. | 28260873 |
| Inflammation, Appendicitis, CTCAE | Altered Intercellular Communication | Should Alvarado and Ohmann scores be real indicators for diagnosis of appendicitis and severity of inflammation? | 28261767 |
| Inflammation, Appendicitis, CTCAE | Altered Intercellular Communication | Alvarado score is better able to predict acute appendicitis and provide an idea of severity of inflammation. | 28261767 |
| Inflammation, Fibrosis Assessment | Altered Intercellular Communication | Galectin 3 (Gal 3) is a b-galactoside-binding lectin known to play a part in inflammation, adverse remodeling and fibrosis. | 28262193 |
| Mastocytosis, Allergy - Charge Type Reason | Altered Intercellular Communication | Mast cell activation syndrome (MCAS), a recently recognized nonneoplastic mast cell disease driving chronic multisystem inflammation and allergy, appears prevalent and thus important. | 28262205 |
| Inflammation | Altered Intercellular Communication | Even though it has been suggested that low doses of radiation may attenuate chronic inflammation, the underlying mechanisms remain elusive. | 28263099 |
| Autoimmune Diseases, Inflammation | Altered Intercellular Communication | Its deficiency results in accumulation of self-DNA, which in turn may induce inflammation and autoimmunity. | 28263100 |
| Myocarditis | Altered Intercellular Communication | Uptake of the radiopharmaceutical F-FDG visualized by PET imaging can reflect abnormal myocardial inflammation. | 28263213 |
| Inflammatory Bowel Diseases, Non-alcoholic Fatty Liver Disease | Altered Intercellular Communication | Intestinal Inflammation Does Not Predict Nonalcoholic Fatty Liver Disease Severity in Inflammatory Bowel Disease Patients. | 28265826 |
| Non-alcoholic Fatty Liver Disease, Metabolic Syndrome X, Gastrointestinal inflammation, ETV3 wt Allele | Altered Intercellular Communication | Both metabolic syndrome (MetS) and intestinal inflammation are implicated in NAFLD pathogenesis. | 28265826 |
| Inflammation, Myelitis, Transverse | Altered Intercellular Communication | Its key features include transverse myelitis, commonly associated with extensive inflammation spanning three or more consecutive vertebral segments. | 28266199 |
| Inflammation | Altered Intercellular Communication | The inflammation seems self-limited, while the role of anti-inflammatory drugs remains obscure. | 28266289 |
| Inflammation | Altered Intercellular Communication | When present in the setting of hypervascularity and/or evidence of active inflammation, the risk increased further to 15-fold. | 28267043 |
| Inflammation | Altered Intercellular Communication | Cases had more evidence of inflammation based on higher Harvey Bradshaw Index values and inflammatory biomarkers and lower hemoglobin values. | 28267043 |
| AURKAIP1 gene, Pancreatitis | Altered Intercellular Communication | Although CP and type 1 AIP are both characterized by the presence of sustained pancreatic inflammation, they are different in terms of the density and hypertrophy of intrapancreatic nerve fibers. | 28270361 |
| Inflammation, Fibrosis Assessment, Abrasion | Altered Intercellular Communication | Pleurodesis is commonly accomplished by draining the pleural fluid, if present, followed by either a mechanical procedure, such as abrasion, pleurectomy, or instillation of a chemical irritant into the pleural space, which results in inflammation and fibrosis which obliterates the pleural space. | 28271362 |
| Inflammation, Cancer-related Cognitive Dysfunction, Memory difficulties | Altered Intercellular Communication | Results suggest that high levels of inflammation alone are not sufficient to account for cognitive difficulties, but may interact with other factors in at-risk populations like LLD, to contribute to memory difficulties. | 28271543 |
| Inflammation, Spondylitis | Altered Intercellular Communication | Successful adalimumab treatment and usefulness of capsule endoscopy for gut inflammation concomitant with ankylosing spondylitis. | 28271948 |
| Inflammation, Spondylitis | Altered Intercellular Communication | Here we describe a 20-year-old man with ankylosing spondylitis and gut inflammation, who was successfully treated with adalimumab. | 28271948 |
| Inflammation, Spondylitis | Altered Intercellular Communication | Adalimumab might be an effective treatment for gut inflammation related to ankylosing spondylitis. | 28271948 |
| Inflammation | Altered Intercellular Communication | Mediators of Inflammation in Asthma: A Forensic Perspective. | 28272089 |
| Inflammation, Asthma | Altered Intercellular Communication | In the clinical setting, the role of systemic inflammation in patients with asthma has attracted increased attention, and some authors showed that increased IL-6 and high-sensitivity C-reactive protein characterized a group of asthmatic patients. | 28272089 |
| Cessation of life, Inflammation, Asthma | Altered Intercellular Communication | A total of 35 autopsy cases were retrospectively selected and included deaths in asthmatic subjects (related and unrelated to severe acute bronchial asthma, in situations characterized or not by systemic inflammation) as well as deaths in nonasthmatic individuals (in situations characterized or not by systemic inflammation). | 28272089 |
| Cessation of life, Inflammation, Asthma | Altered Intercellular Communication | Accordingly, postmortem serum IL-6 values in cases of death during severe acute bronchial asthma can be measured and considered of diagnostic relevance to estimate the magnitude of the systemic inflammation responses characterizing the disease. | 28272089 |
| Inflammation, Granuloma | Altered Intercellular Communication | In spite of a good safety profile, biologic TNF antagonists may induce paradoxical inflammation, which can manifest as sarcoid-like granulomatosis, consisting of noncaseating granulomas in the affected organs. | 28272203 |
| Inflammation, Primary malignant neoplasm | Altered Intercellular Communication | This study suggests an association between frailty and inflammation in older adults with cancer. | 28273043 |
| Inflammation, Asthma, Allergic | Altered Intercellular Communication | IL-33 is a tissue-derived cytokine that induces and amplifies eosinophilic inflammation and has emerged as a promising new drug target for asthma and allergic disease. | 28273074 |
| Inflammation, Transitional cell carcinoma of bladder | Altered Intercellular Communication | Role of Inflammation in the Perioperative Management of Urothelial Bladder Cancer With Squamous-Cell Features: Impact of Neutrophil-to-Lymphocyte Ratio on Outcomes and Response to Neoadjuvant Chemotherapy. | 28274590 |
| Inflammation, Epithelioma | Altered Intercellular Communication | Neutrophil-to-lymphocyte ratio (NLR) might reflect an increased neutrophilic inflammatory response, and urothelial tumors with squamous-cell features (SqD) have been linked to inflammation. | 28274590 |
| Inflammation, Colorectal Carcinoma | Altered Intercellular Communication | We calculated relative and absolute risks of CRC for PLP and the ratios 3-hydroxykynurenine:XA (HK:XA), an inverse marker of functional vitamin B-6 status, and PA:(PLP + pyridoxal) (PAr), a marker of inflammation and oxidative stress and an inverse marker of vitamin B-6 status.Results: Plasma PLP concentrations were associated with a reduced CRC risk for the third compared with the first quartile and for PLP sufficiency compared with deficiency [OR: 0.60 (95% CI: 0.44, 0.81) and OR: 0.55 (95% CI: 0.37, 0.81), respectively]. | 28275126 |
| Inflammation, Neoplasms | Altered Intercellular Communication | Furthermore, our analyses of novel markers of functional vitamin B-6 status and vitamin B-6-associated oxidative stress and inflammation suggest a role in tumor progression rather than initiation. | 28275126 |
| Inflammation, Atrial Fibrillation by ECG Finding | Altered Intercellular Communication | Inflammation has further been linked to atrial fibrillation (AF). | 28276729 |
| Perifolliculitis | Altered Intercellular Communication | All consenting household residents aged 1 year and above were examined for trachomatous inflammation-follicular (TF), trachomatous inflammation-intense (TI) and trichiasis. | 28276755 |
| amyloid-beta binding, Inflammation, Cognition Disorders, Blood Circulation | Altered Intercellular Communication | In the brain, amyloid-beta generation participates in the pathophysiology of cognitive disorders; in the bloodstream, the role of amyloid-beta is uncertain but may be linked to sterile inflammation and senescence. | 28279654 |
| Inflammation, physiopathological | Altered Intercellular Communication | These findings indicate that circulating levels of LCN-2 in patients after AP may play a role in chronic low grade inflammation associated with abdominal adiposity and that alcohol consumption may further exacerbate adipose tissue dysfunction. | 28279688 |
| Inflammation | Altered Intercellular Communication | Kcne2 deletion also caused extensive pancreatic transcriptome changes consistent with facets of T2DM, including endoplasmic reticulum stress, inflammation, and hyperproliferation. | 28280005 |
| Inflammation, Neoplasms | Altered Intercellular Communication | Emerging evidence suggests that p53 dysfunction also fuels inflammation and supports tumor immune evasion, thereby serving as an immunological driver of tumorigenesis. | 28280037 |
| Inflammation, Observation Method - Coagulation, Atherosclerosis | Altered Intercellular Communication | Inflammation, coagulation, and cell stress contribute to atherosclerosis and its adverse events. | 28280039 |
| Airway structure, Inflammation, Fibrosis Assessment | Altered Intercellular Communication | In infants and young children with cystic fibrosis, lower airway infection and inflammation are associated with adverse respiratory outcomes. | 28280235 |
| Airway structure, Fibrosis Assessment | Altered Intercellular Communication | Detection of recognised cystic fibrosis bacterial pathogens was associated with reduced microbial diversity and greater lower airway inflammation. | 28280235 |
| Airway structure, Fibrosis Assessment | Altered Intercellular Communication | Dominance of the microbiota by recognised cystic fibrosis bacterial pathogens is associated with increased lower airway inflammation, however early microbial diversity is not associated with pulmonary function at 6 years of age. | 28280235 |
| Inflammation, acetate-CoA ligase activity, Calcification of coronary artery | Altered Intercellular Communication | In the present study, we explored the relationship between the NLR and CACS in terms of subclinical inflammation and coronary artery calcification. | 28280728 |
| Inflammation, Choroiditis | Altered Intercellular Communication | Multimodal imaging shows that inflammation of the choriocapillaris is a main pathology of serpiginous choroiditis. | 28281863 |
| Chronic kidney disease stage 5, Inflammation, Kidney Failure, Chronic | Altered Intercellular Communication | Additionally, it is known that peritoneal inflammation can be correlated with systemic inflammation and this could contribute to the compromised rHuEPO required dose in anemic patients with end stage renal disease (ESRD). | 28282547 |
| Kidney Failure, Chronic, Inflammation, Anemia | Altered Intercellular Communication | Our study found increased IL-17 and IFN-g plasma, but no dialysate levels, in patients receiving higher doses of rHuEPO, suggesting may exist a relationship between systemic inflammation of ESRD, and the necessary levels of rHuEPO for the correction of anemia in these patients. | 28282547 |
| Fibrosis Assessment, Hepatitis | Altered Intercellular Communication | Het OTC-KO female mice showed evidence of liver inflammation and the eventual development of significant fibrosis. | 28283349 |
| Impaired cognition, Zebrafish | Altered Intercellular Communication | The present results: a. reveal regional differences in de-regulated gene expression between the anterior horn of the spinal cord and frontal cortex area 8 in the same individuals suffering from sALS; b. validate and extend our knowledge about the complexity of the inflammatory response in the anterior horn of the spinal cord; and c. identify for the first time extensive gene up-regulation of neurotransmission and synaptic-related genes, together with significant down-regulation of oligodendrocyte- and myelin-related genes, as important contributors to the pathogenesis of frontal cortex alterations in the sALS/frontotemporal lobar degeneration spectrum complex at stages with no apparent cognitive impairment. | 28283675 |
| Gastrointestinal inflammation | Altered Intercellular Communication | It is suggested that AIM may contribute to intestinal inflammation by inhibiting the apoptosis of macrophages. | 28284201 |
| Inflammation, Neuromyelitis Optica, MS gene | Altered Intercellular Communication | Soluble CD40 ligand contributes to blood-brain barrier breakdown and central nervous system inflammation in multiple sclerosis and neuromyelitis optica spectrum disorder. | 28284329 |
| Inflammation | Altered Intercellular Communication | sCD40L could be involved in BBB disruption in MS, whereas it may contribute to CNS inflammation in NMOSD. | 28284329 |
| Inflammation, Axonal neuropathy, Demyelination, Inflammatory disorder | Altered Intercellular Communication | Multiple sclerosis (MS) is an inflammatory disease of the central nervous system (CNS), where inflammation, demyelination together with the axonopathy are the cardinal features on pathologic ground, with a combined genetic and environmental background. | 28284331 |
| Chronic lymphocytic inflammation, Pontine structure, Clippers | Altered Intercellular Communication | Chronic lymphocytic inflammation with pontine perivascular enhancement responsive to steroids (CLIPPERS): A lymphocytic reactive response of the central nervous system? | 28284348 |
| Chronic lymphocytic inflammation, Pontine structure, Clippers | Altered Intercellular Communication | Chronic lymphocytic inflammation with pontine perivascular enhancement responsive to steroid (CLIPPERS) was first described in 2010. | 28284348 |
| Acute myocardial infarction, Left ventricular systolic dysfunction | Altered Intercellular Communication | Increased levels of neuro-hormonal biomarkers predict poor prognosis in patients with acute myocardial infarction (AMI) complicated by left ventricular systolic dysfunction (LVSD). | 28284500 |
| Structure of suprasellar region, Impaired cognition, Pituitary Adenoma | Altered Intercellular Communication | Patients suffering from pituitary adenomas may experience cognitive dysfunctions due to hormonal imbalance or suprasellar tumor extension displacing neural structures. | 28284581 |
| Inflammation, Empyema | Altered Intercellular Communication | Acute inflammation with empyema and peripancreatic liquid collection was observed in 14 patients (12 in Group 1, 2 in Group 2), and conversion to OS was statistically significantly higher in Group 1 (p=0.016). | 28284749 |
| Inflammation, Periodontitis, "Alzheimers Disease", Data types - Address, Periodontal Diseases | Altered Intercellular Communication | Although the pathogeneses of Alzheimer's disease (AD) and periodontal diseases have overlapping features, including ageing and chronic inflammation, the association between AD and periodontitis remains unclear. | 28285126 |
| Enteritis | Altered Intercellular Communication | Patients with increased permeability (n = 39) and randomly selected subjects with normal permeability (n = 59) were then examined by VCE for signs of small bowel inflammation and subclinical CD. | 28286191 |
| Inflammation, Ulcerative Colitis | Altered Intercellular Communication | Severity of inflammation in patients with UC was assessed by Mayo score and in patients with CD by 4-grade system. | 28286192 |
| Inflammation, Crypt abscess, Ulceration, CTCAE, Superficial ulcer | Altered Intercellular Communication | Biopsies were assessed for signs of active inflammation, erosion or ulceration, and crypt abscesses and assigned a histologic score. | 28286192 |
| Superficial ulcer, Inflammation, Ulcer | Altered Intercellular Communication | At Week 52, a total of 38 patients (54.3%) were still in clinical remission or still had a clinical response; 29 patients (41.4%) had mucosal healing, defined as complete healing of erosions or ulcerations, and 20 patients (27.7%) had histologic healing, defined as complete absence of markers of inflammation. | 28286192 |
| Inflammation, Lupus Erythematosus, Bacterial Infections, Lupus Erythematosus, Systemic | Altered Intercellular Communication | C-reactive protein (CRP), a marker for inflammation, indicates bacterial infection in systemic lupus erythematosus (SLE) when markedly elevated. | 28286229 |
| Inflammation | Altered Intercellular Communication | PKC-epsilon and TLR4 synergistically regulate resistin-mediated inflammation in human macrophages. | 28286252 |
| Cardiac complication, atherosclerotic | Altered Intercellular Communication | Resistin has been associated with atherosclerotic inflammation and cardiovascular complications. | 28286252 |
| Inflammation | Altered Intercellular Communication | PKCe is a key upstream mediator in resistin-induced inflammation that may interact synergistically with TLR4 to promote NF-kB activation, while TRAM is an important signal. | 28286252 |
| atherosclerotic | Altered Intercellular Communication | PKCe and TRAM may represent novel molecular targets for resistin-associated chronic atherosclerotic inflammation. | 28286252 |
| Sepsis, Inflammation | Altered Intercellular Communication | Natural killer (NK) cells play a crucial role in the pathophysiology of sepsis, leading to exaggerated inflammation due their rapid response and production of pro-inflammatory cytokines such as interferon gamma (IFN-g). | 28287491 |
| Malnutrition, Inflammation, Atrophy of thymus gland | Altered Intercellular Communication | Malnutrition and inflammation are associated with thymus atrophy, and thymus area seems positively associated with plasma phosphate. | 28288591 |
| Inflammation, Vasculitis, CTCAE | Altered Intercellular Communication | The kinin system is activated during vasculitis and may contribute to chronic inflammation. | 28289183 |
| Inflammation, Hormone Receptor Positive Breast Carcinoma | Altered Intercellular Communication | Thus, B1 receptor-positive endothelial microvesicles may contribute to chronic inflammation by inducing neutrophil chemotaxis, and the reduction of these microvesicles by C1-inhibitor should be explored as a potential treatment for neutrophil-induced inflammation. | 28289183 |
| Inflammation, diabetic ulcer | Altered Intercellular Communication | In particular, defective transition from pro-inflammatory (M1) to anti-inflammatory (M2) behavior has been implicated as a potential source of sustained inflammation that prevents healing of chronic wounds such as diabetic ulcers. | 28290581 |
| Acute Kidney Injury, CTCAE, Inflammation, Pneumonia | Altered Intercellular Communication | Because pneumonia and acute kidney injury are in part mediated by inflammation, we hypothesized that when acute kidney injury complicates pneumonia, major adverse kidney events outcomes would be exacerbated. | 28291091 |
| skin damage, Inflammation | Altered Intercellular Communication | As the number of Langerhans cells was not reduced in the undisturbed neighboring skin, the depletion of epidermal Langerhans cells did not precede skin damage but was a cause of prolonged severe inflammation. | 28291135 |
| hepcidin, Anemia | Altered Intercellular Communication | Excessive hepcidin signaling causes anemia in chronic inflammatory conditions by restricting iron delivery to the bone marrow. | 28291504 |
| Inflammatory Bowel Diseases, Acute inflammation | Altered Intercellular Communication | Caution is warranted in patients with active IBD, since the exact impact of active bowel inflammation could not be determined retrospectively. | 28291546 |
| Aggressive course, Inflammation | Altered Intercellular Communication | Intratumoral inflammation was found to be associated with aggressive prostate cancer. | 28292923 |
| Inflammation, Prostatic Neoplasms | Altered Intercellular Communication | We and others have shown that prostate tumors in African-American (AA) patients harbor a distinct immune and inflammation signature when compared with European-American (EA) patients. | 28292923 |
| Inflammation | Altered Intercellular Communication | Our findings could not be accounted for by psychological distress and suggest that non-CNS cancer may directly and/or indirectly affect the brain via mechanisms such as tumor-induced neurogenesis, inflammation, and/or vascular changes, for example. | 28293478 |
| Rheumatoid Arthritis | Altered Intercellular Communication | Semiquantitative Evaluation of Extrasynovial Soft Tissue Inflammation in the Shoulders of Patients with Polymyalgia Rheumatica and Elderly-Onset Rheumatoid Arthritis by Power Doppler Ultrasound. | 28293635 |
| Inflammation, Rheumatoid Arthritis, Musculoskeletal Pain | Altered Intercellular Communication | To develop a scoring system for evaluating the extrasynovial soft tissue inflammation of the shoulders in patients with polymyalgia rheumatica (PMR) and elderly-onset rheumatoid arthritis with PMR-like onset (pm-EORA) using ultrasound. | 28293635 |
| Inflammation, Endothelial dysfunction | Altered Intercellular Communication | Target prediction and network analyses identified several interactions between miRNA targets and biomarkers related to inflammation, angiogenesis and endothelial dysfunction. | 28293796 |
| Inflammation, Primary malignant neoplasm, Neoplasms, Obesity | Altered Intercellular Communication | Obesity is associated with tumor promoting pathways related to insulin resistance and chronic low-grade inflammation which have been linked to various disease states, including cancer. | 28293912 |
| Gingivitis, Calculi, Dental Plaque | Altered Intercellular Communication | A full-mouth clinical examination was performed in order to assess dental plaque, dental calculus and gingival inflammation. | 28294149 |
| Gingivitis, Dental Plaque | Altered Intercellular Communication | All-cause mortality risk were raised with dental plaque, gingival inflammation, >10 missing teeth and functional masticatory units <5. | 28294149 |
| Gingivitis, Dental Plaque | Altered Intercellular Communication | All-cancer mortality was positively associated with dental plaque and gingival inflammation. | 28294149 |
| Gingivitis, Dental Plaque, Non-Cancer Related Death | Altered Intercellular Communication | Non-cardiovascular and non-cancer mortality were also positively associated with high dental plaque (HR = 3.30, [95% CI: 1.76-6.17]), high gingival inflammation (HR = 2.86, [95% CI: 1.71-4.79]), >10 missing teeth (HR = 2.31, [95% CI: 1.40-3.82]) and functional masticatory units <5 (HR = 2.40 [95% CI 1.55-3.73]). | 28294149 |
| Inflammation, Neurotoxicity Syndromes | Altered Intercellular Communication | Our findings propose neuronal microtubule instability as a novel mechanism of HIV neurotoxicity, without evidence of enhanced inflammation. | 28295345 |
| Uremia, Inflammation, Malnutrition, Infection | Altered Intercellular Communication | Infections in hemodialysis patients are mainly caused by venous catheters, uremia, malnutrition and inflammation. | 28296195 |
| Inflammation, "Extra-osseous Ewings sarcoma | Altered Intercellular Communication | Given that GCTs occur at sites of scarring and inflammation, we sought to determine the prevalence of EoE in patients with esophageal GCTs. | 28296675 |
| ACSM3 gene, Inflammation, Subarachnoid Hemorrhage, Aneurysmal | Altered Intercellular Communication | Reduction of inflammation after administration of interleukin-1 receptor antagonist following aneurysmal subarachnoid hemorrhage: results of the Subcutaneous Interleukin-1Ra in SAH (SCIL-SAH) study. | 28298024 |
| Inflammation, Brain Injuries, ASAH1 gene, Cerebral Ischemia | Altered Intercellular Communication | Inflammation, mediated by the cytokine interleukin-1 (IL-1), is an important contributor to cerebral ischemia after diverse forms of brain injury, including aSAH. | 28298024 |
| Inflammation, ASAH1 gene | Altered Intercellular Communication | The authors hypothesized that administration of additional subcutaneous IL-1Ra would reduce inflammation and associated plasma markers associated with poor outcome following aSAH. | 28298024 |
| Inflammation, Abnormality of carotid artery | Altered Intercellular Communication | Further imaging with computed tomography and positron emission tomography demonstrated resolution of her left carotid artery abnormality, but new wall thickening and inflammation in her right carotid artery, abdominal aorta, and superior mesenteric artery. | 28298242 |
| Myelodysplasia, Vasculitis of large artery, Sore to touch, Inflammation | Altered Intercellular Communication | Large vessel vasculitis in older individuals presenting with atypical clinical features, such as a migratory pattern of affected vessels, vessel wall tenderness, and marked systemic inflammation, should prompt a search for underlying myelodysplasia. | 28298242 |
| Airway structure, Chronic Obstructive Airway Disease, Exacerbation | Altered Intercellular Communication | Antimicrobial peptide levels are linked to airway inflammation, bacterial colonisation and exacerbations in chronic obstructive pulmonary disease. | 28298400 |
| Communicable Diseases, Inflammation | Altered Intercellular Communication | Antimicrobial peptides (AMPs) are effectors of host defence against infection, inflammation and wound repair. | 28298400 |
| ARCN1 gene, Communicable Diseases, Airway structure | Altered Intercellular Communication | In stable COPD, high sputum hCAP18/LL-37 levels were associated with increased risk of AECOPD, non-typeable Haemophilus influenzae colonisation, higher age, ex-smoking and higher levels of inflammatory markers.Altered levels of selected AMPs are linked to airway inflammation, infection and AECOPD, suggesting a role for these peptides in airway defence mechanisms in COPD. | 28298400 |
| Herpes Simplex Infections, Inflammation, Communicable Diseases | Altered Intercellular Communication | The absence of markers of inflammation in the cerebrospinal fluid (CSF) commonly predicts the absence of herpes simplex virus (HSV) central nervous system (CNS) infection. | 28298450 |
| Inflammation, Obesity, Abdominal, Miller Dieker syndrome | Altered Intercellular Communication | Furthermore, the association between MDS and fasting glucose was fully mediated by adiposity, especially by WC in men aged <45 y and in premenopausal women.Conclusion: Our results suggest that reducing abdominal obesity may play an important role in the pathway through which Med-diet consumption reduces insulin resistance and inflammation. | 28298537 |
| Inflammation, Atrial Fibrillation by ECG Finding, osteoclast activating factor | Altered Intercellular Communication | It has been shown that inflammation and oxidative stress are important factors in postoperative atrial fibrillation (POAF). | 28299332 |
| Inflammation, Uveomeningoencephalitic Syndrome | Altered Intercellular Communication | The origin of inflammation was primarily in the choroid in VKH and in both the choroid and retina in BRC. | 28299496 |
| Inflammation | Altered Intercellular Communication | They constitute chronic low-grade inflammation environment to adjacent cells and tissues. | 28299617 |
| Inflammation, Degenerative disorder | Altered Intercellular Communication | Therefore, this compound might be effective in alleviating chronic low-grade inflammation linked to age-related degenerative disorders. | 28299617 |
| Suppuration, Inflammation, Hidradenitis | Altered Intercellular Communication | When associated with inflammation, resembling hidradenitis, it is called steatocystoma multiplex suppurativa, a condition rarely reported. | 28300893 |
| Kidney Failure, Chronic, Hypothyroidism | Altered Intercellular Communication | End-stage renal disease (ESRD) is associated with perturbations in thyroid hormone concentrations and an increased prevalence of hypothyroidism. | 28301073 |
| Community acquired pneumonia | Altered Intercellular Communication | Inflammation biomarkers in blood as mortality predictors in community-acquired pneumonia admitted patients: Importance of comparison with neutrophil count percentage or neutrophil-lymphocyte ratio. | 28301543 |
| Inflammation, Community acquired pneumonia | Altered Intercellular Communication | The increase and persistence of inflammation in community-acquired pneumonia (CAP) patients can lead to higher mortality. | 28301543 |
| Inflammation, MS gene | Altered Intercellular Communication | MicroRNA-142 regulates inflammation and T cell differentiation in an animal model of multiple sclerosis. | 28302134 |
| Inflammation, Squamous cell carcinoma, S100A4 protein, human | Altered Intercellular Communication | Rarely, chronic inflammation and recurrent disease leads to malignant transformation, most commonly to squamous cell carcinoma (SCC). | 28302173 |
| Inflammation, Symphysis Pubis Dysfunction | Altered Intercellular Communication | Malignant transformation should be suspected in chronic SPD with recurrent episodes of inflammation, repeated purulent discharge, poor healing, and chronic complex fistulas. | 28302173 |
| vascular inflammations, Ischemic stroke, Cerebrovascular accident | Altered Intercellular Communication | In non-cardiogenic ischemic stroke, pravastatin treatment may reduce vascular inflammation as assessed by Hs-CRP, and higher Hs-CRP levels appeared to increase the risk of recurrent stroke and vascular events. | 28302952 |
| Inflammation, Pulmonary Hypertension | Altered Intercellular Communication | Inflammation is an increasingly recognized hallmark of pulmonary hypertension (PH). | 28303379 |
| Inflammation, Thrombosis | Altered Intercellular Communication | Mean platelets volume (MPV) is a marker, which indicates platelet function, and is a potential link between inflammation and thrombosis. | 28303662 |
| Granulomatous inflammation, Necrosis | Altered Intercellular Communication | Lacrimal gland biopsy revealed a perivascular granulomatous inflammation with necrotic foci. | 28306365 |
| Inflammation | Altered Intercellular Communication | High physical fitness is associated with reduction in basal- and exercise-induced inflammation. | 28314078 |
| Duodenal Adenoma, Inflammation, polyps, Adenocarcinoma of duodenum | Altered Intercellular Communication | Eighteen patients had preoperative diagnosis of duodenal adenomatosis, three patients had preoperative diagnosis of duodenal adenocarcinoma, one had a bleeding polyp and two had localized inflammation. | 28314316 |
| Dual-probe in Situ Hybridization, Hyperostosis, Diffuse Idiopathic Skeletal, Calcinosis, Osteogenesis | Altered Intercellular Communication | Diffuse idiopathic skeletal hyperostosis (DISH) is a non-inflammatory condition characterised by calcification and ossification of the vertebral ligaments. | 28314808 |
| Stomach Carcinoma, Neoplasms | Altered Intercellular Communication | Inflammation-based indexes and clinicopathologic features are strong predictive values of preoperative circulating tumor cell detection in gastric cancer patients. | 28315180 |
| Ulcerative Colitis, Inflammatory disease of mucous membrane | Altered Intercellular Communication | Conclusion In UC, the new I-SCAN OE technology accurately identified mucosal inflammation, and correlated well with histological scores of chronic and acute changes. | 28315280 |
| Inflammation, Primary malignant neoplasm, Esophagitis | Altered Intercellular Communication | HLA-DR expression increased early in the inflammation to cancer progression sequence; with higher expression detected in esophagitis and BE compared to normal tissue. | 28315927 |
| TNF protein, human, Inflammation, Degenerative polyarthritis, Refractory anemias | Altered Intercellular Communication | Interestingly, parallel to the severity of inflammation, proinflammatory mediators IL-1b, TNF-a, and 5-LOX specific mRNA as well as immunoreactive (IR) cells were significantly more abundant in patients with RA and JT than in those with OA. | 28316377 |
| Refractory anemias, Inflammation, Degenerative polyarthritis | Altered Intercellular Communication | These findings show that upregulation of proinflammatory mediators contributes to the predominantly catabolic inflammatory process in JT and RA synovium, whereas upregulation of anabolic anti-inflammatory mediators counteracts inflammation resulting in the inferior inflammatory process in OA synovium. | 28316377 |
| Presenile dementia, Inflammation, Impaired cognition | Altered Intercellular Communication | We hypothesized that poor periodontal health status may be associated with cognitive impairment and dementia via the exacerbation of systemic inflammation. | 28317488 |
| Inflammation, Psychiatric | Altered Intercellular Communication | Based on the periodontal and psychiatric examinations and the cytokine levels produced by unstimulated and LPS-stimulated PBL isolated from 128 participants, we have examined if the coexisting of these two clinically described conditions may have influence on the systemic inflammation. | 28317488 |
| Inflammation, Impaired cognition | Altered Intercellular Communication | These results confirm that the presence of cognitive decline and the additional source of proinflammatory mediators, like periodontal health problems, aggravate the systemic inflammation. | 28317488 |
| Ocular Hypotension, Panuveitis, Inflammatory abnormality of the eye, Uveitis, Tuberculosis, Ocular | Altered Intercellular Communication | Most common type of ocular inflammation causing hypotony was panuveitis (14, 46.6%), and ocular tuberculosis (5; 23.8%) was the most common cause of uveitis in these patients. | 28318342 |
| Macular Edema, Cystoid, Inflammation, Uveitis | Altered Intercellular Communication | Clinical Outcomes of Intravitreal Preservative-Free Triamcinolone Preparation (Triesence(r)) for Cystoid Macular Oedema and Inflammation in Patients with Uveitis. | 28318344 |
| Inflammation, Fibrosis Assessment | Altered Intercellular Communication | CS patients with LGE alone or in association with FDG were at similar risk of future events, which suggests that outcomes may be driven by the presence of LGE (myocardial fibrosis) and not FDG (inflammation). | 28318664 |
| Inflammation, Hemorrhage | Altered Intercellular Communication | This is followed by the proliferation of mesenchymal elements with angiogenesis and inflammation, which in turn becomes a substrate for repeated hemorrhage and expansion of the lesion. | 28319470 |
| Hypertensive disease, Inflammation | Altered Intercellular Communication | Finally, mice were exposed to HBP with and without heparin derivatives and the kidneys examined for signs of inflammation. | 28319494 |
| Inflammation | Altered Intercellular Communication | MicroRNA-155, which has been shown to play a central role in inflammation and neovascularization, was upregulated with long-term LVAD support. | 28319523 |
| Inflammation, Obesity | Altered Intercellular Communication | Obesity is characterized by chronic low-grade inflammation driven by activation and tissue infiltration of circulating leukocytes. | 28319586 |
| Inflammation | Altered Intercellular Communication | Oxidative lipid damage is associated with inflammation and the ANS. | 28319849 |
| Inflammation, Sample Size Calculation | Altered Intercellular Communication | This signature may provide novel insights linking endothelial inflammation and defective repair processes in the pathogenesis of SSc. | 28320472 |
| Chronic Obstructive Airway Disease, Pneumonitis | Altered Intercellular Communication | There is preclinical evidence that consumption of berryfruit extract may reduce chronic airways inflammation and modify airway remodelling in allergen-induced models of lung inflammation. | 28320793 |
| Asthma, Eosinophilic inflammation | Altered Intercellular Communication | In steroid-naive participants with mild asthma and elevated FeNO, there was no effect of BFPE on FeNO, a biomarker of eosinophilic airways inflammation. | 28320793 |
| Lung Diseases, Interstitial, Pneumonitis | Altered Intercellular Communication | Arterial Carboxyhemoglobin Measurement Is Useful for Evaluating Pulmonary Inflammation in Subjects with Interstitial Lung Disease. | 28321059 |
| Pneumonitis | Altered Intercellular Communication | Conclusion The CO-Hb levels of subjects with ILD were increased, particularly during an exacerbation, and were correlated with the parameters that reflect pulmonary inflammation. | 28321059 |
| Inflammation, Venous Thromboembolism, vinyltriethoxysilane | Altered Intercellular Communication | Recent gene knockout studies on mice have shown the role of toll-like receptor 9 (TLR9) in resolution of venous thromboembolism (VTE) through sterile inflammation. | 28321710 |
| Microalbuminuria, Inflammation | Altered Intercellular Communication | In addition, elevated hs-CRP increased the risk of developing microalbuminuria in subjects with CVD risk factors, indicating that chronic inflammation could amplify the deterioration of kidney by effect of CVD risk factors. | 28322017 |
| allergic inflammation | Altered Intercellular Communication | This study shows that IgE levels are associated with DNA methylation levels at numerous CpG sites, which might provide new leads for investigating the links between IgE and allergic inflammation. | 28322575 |
| Nephritis | Altered Intercellular Communication | PPARa activation by MHY908 attenuates age-related renal inflammation through modulation of the ROS/Akt/FoxO1 pathway. | 28323024 |
| Nephritis | Altered Intercellular Communication | However, the mechanism underlying MHY908-mediated amelioration of renal inflammation with insulin resistance during aging remains unknown. | 28323024 |
| Inflammation | Altered Intercellular Communication | One group of thiol containing proteins, peroxiredoxins, in particular, have been associated with inflammation. | 28323130 |
| Degenerative polyarthritis, Inflammation | Altered Intercellular Communication | Inflammation is part of osteoarthritis' pathophysiology, and surgery induces a marked inflammatory response. | 28323139 |
| Inflammation, Pain Distress Question | Altered Intercellular Communication | We aimed to investigate whether (1) inflammation is associated with functional performance, knee-extension strength, and knee pain before TKA; (2) PST affects inflammation, and the inflammatory state over time; (3) baseline or surgery-induced inflammation modifies the effect of rehabilitation +- PST on change in 6-min walk test (D6MWT); and (4) baseline or surgery-induced inflammation is associated with D6MWT following TKA. | 28323139 |
| Vaginitis | Altered Intercellular Communication | The safety was compared through the results of vaginal findings and vaginal inflammation markers before and after treatment. | 28323291 |
| Refractory anemias, Inflammation, Rheumatoid Arthritis | Altered Intercellular Communication | Inflammation and angiogenesis are a significant element of pathogenesis in rheumatoid arthritis (RA). | 28323906 |
| Refractory anemias, Inflammation | Altered Intercellular Communication | The FLT-1- triggering factor for production of proinflammatory cytokines-might contributes to inflammation in patients with RA. | 28323906 |
| Inflammation, Diabetes Mellitus, Non-Insulin-Dependent | Altered Intercellular Communication | Postprandial dysmetabolism in type 2 diabetes (T2D) is exacerbated by prolonged sitting and may trigger inflammation and oxidative stress. | 28323950 |
| Inflammation | Altered Intercellular Communication | Compared with SIT, LW and SRA were associated with reductions in lipids associated with inflammation; increased concentrations of lipids associated with antioxidant capacity; and differential changes in species associated with platelet activation. | 28323950 |
| Inflammation | Altered Intercellular Communication | Low-dose aspirin (LDA) may improve reproductive success in women with chronic, low-grade inflammation. | 28323989 |
| Inflammation, Pregnancy loss | Altered Intercellular Communication | In women attempting conception with elevated hsCRP and prior pregnancy loss, LDA may increase clinical pregnancy and live birth rates compared with women without inflammation and reduce hsCRP elevation during pregnancy. | 28323989 |
| Inflammation | Altered Intercellular Communication | The expression of genes specific for T1D inflammation was associated with the abundance of specific bacteria in the duodenum. | 28324102 |
| Inflammation, Carcinogenesis, Malignant Neoplasms | Altered Intercellular Communication | Interaction between inflammation, immunity and carcinogenesis occurs in different cancers; however, the potential roles of different molecules involved in these processes in relation to ovarian carcinogenesis were not fully investigated. | 28325363 |
| Inflammation | Altered Intercellular Communication | In addition, GG genotype of IL4RA rs8832 was associated with type-2 endotype, whereas A allele of ADAM33 T_2 was associated with mixed type of eosinophilic/type-2 and neutrophilic inflammations. | 28326636 |
| ARCN1 gene | Altered Intercellular Communication | These unique data indicate that the current model for airway wall inflammation in COPD is oversimplified, and contrast with innate inflammatory activation in the lumen, at least in mild-moderate disease. | 28326668 |
| Inflammation, Chronic pain | Altered Intercellular Communication | We sought to investigate the relationship between inflammation and chronic pain in PLWH. | 28328552 |
| Inflammatory abnormality of the eye | Altered Intercellular Communication | Over 1 month, an 81-year-old man developed progressive left periocular inflammation unresponsive to treatment. | 28328558 |
| Angiectasis, Inflammation, Thrombosis, Hemorrhage, Necrosis | Altered Intercellular Communication | Conjunctival biopsy showed acute inflammation with necrosis, vascular ectasia with thrombosis and hemorrhage. | 28328595 |
| Inflammation | Altered Intercellular Communication | Only in patients with a confirmed eGFR less than 60 ml/min per 1.73 m at inclusion, a higher soluble-CIADIS weighted score (increased inflammation) was associated with a steeper decrease of renal function of -2.3 (ml/min per 1.73 m) per year (95% CI -3.6 to -1.0). | 28328797 |
| Inflammation, Fever, CTCAE, Thromboembolism | Altered Intercellular Communication | Eculizumab allowed the resolution of fever and inflammation, and prevented further thromboembolism. | 28328837 |
| Inflammation, Fever, CTCAE | Altered Intercellular Communication | Thromboses, as observed in our case, may be associated with fever and marked inflammation. | 28328837 |
| Myocarditis, Myocarditis, CTCAE 5.0 | Altered Intercellular Communication | Tissue characterization by T1 and T2 mapping cardiovascular magnetic resonance imaging to monitor myocardial inflammation in healing myocarditis. | 28329275 |
| Myocarditis, Myocarditis, CTCAE 5.0 | Altered Intercellular Communication | This study evaluated the ability of T1 and T2 mapping cardiovascular magnetic resonance (CMR) to monitor the course of myocardial inflammation in healing myocarditis. | 28329275 |
| deficiency aspects, Inflammation, physiopathological, Neoplasms | Altered Intercellular Communication | Sleep deficiency is linked to metabolic dysfunction and chronic inflammation, which may contribute to higher mortality from cardiometabolic conditions and promote tumor progression. | 28329353 |
| Inflammation, Necrosis | Altered Intercellular Communication | A skin biopsy revealedgranulomatous inflammation in the deep dermisand the subcutaneous fat with foci of necrosis.Within the foci of necrosis were large histiocytoidstructures with prominent nuclei. | 28329521 |
| Inflammation, Swelling, FBN1 gene, Facial paralysis | Altered Intercellular Communication | A 56-year-old male patient with Marfan syndrome presented with swelling and inflammation of the left parotid gland associated with progressively complete facial nerve paralysis. | 28330578 |
| Inflammation, Squamous metaplasia, Necrosis | Altered Intercellular Communication | The histological examination of a biopsy showed a lobulocentric process with necrosis, squamous metaplasia, and inflammation. | 28330578 |
| Inflammation, Brain Diseases, Cognition Disorders, Neuronal loss in central nervous system | Altered Intercellular Communication | TMEM106B risk variants are associated with inflammation, neuronal loss, and cognitive deficits, even in the absence of known brain disease, and their impact is highly selective for the frontal cerebral cortex of older individuals (>65 years). | 28330615 |
| Inflammation, Dyslipidemias, Dysglycemia, Hypertension, CTCAE | Altered Intercellular Communication | MESA study participants with higher pericardial and hepatic fat were more likely to be older, were more frequently men, and had a higher prevalence of cardiometabolic risk factors (including dysglycemia, dyslipidemia, hypertension), as well as adiposity-associated inflammation. | 28330662 |
| Inflammation, Acute Kidney Tubular Necrosis, Fibrosis Assessment | Altered Intercellular Communication | In contrast, expression of the NTT-MMP-2 isoform resulted in a dramatic increase in tubular cell necrosis, inflammation, and fibrosis. | 28331061 |
| ARCN1 gene, Deficiency of butyryl-CoA dehydrogenase, Inflammation, Endothelial dysfunction | Altered Intercellular Communication | Patients with SCAD and concomitant COPD are at high risk of cardiovascular adverse events, due to chronic inflammation, responsible of endothelial dysfunction, oxidative stress and heightened platelet reactivity (PR). | 28331925 |
| Chronic Kidney Diseases | Altered Intercellular Communication | Elevated intact parathyroid hormone (iPTH) levels can contribute to morbidity and mortality in children with chronic kidney disease (CKD). | 28332096 |
| Parkinson Disease, Impaired cognition | Altered Intercellular Communication | Phenotype of postural instability/gait difficulty in Parkinson disease: relevance to cognitive impairment and mechanism relating pathological proteins and neurotransmitters. | 28332604 |
| Impaired cognition | Altered Intercellular Communication | The relationships between motor phenotypes and cognitive impairment and the underlying mechanisms relating pathological proteins and neurotransmitters in cerebrospinal fluid (CSF) are unknown. | 28332604 |
| Inflammation, Periodontitis | Altered Intercellular Communication | Additionally, whether this association was independent of periodontitis, and a systemic marker of inflammation, serum C-reactive protein (CRP) was examined. | 28332718 |
| Airway structure, Asthma | Altered Intercellular Communication | In addition, age at asthma onset appears to influence airway inflammation in patients with CAL. | 28332897 |
| Parkinson Disease, Inflammation | Altered Intercellular Communication | The study suggested that there may be a reduced capacity for the IgG to inhibit Fcg-RIIIa binding, which would allow an increased ability for the IgG to cause antibody-dependent cell cytotoxicity and a possible state of low-grade inflammation in individuals with Parkinson's disease. | 28334832 |
| Inflammation, Gait impairment | Altered Intercellular Communication | A 68-year-old Hispanic female with a previous history of bilateral knee arthroplasty presented with acute right-knee inflammation and gait impairment. | 28335753 |
| Inflammation, Traumatic injury, Allergy - Charge Type Reason | Altered Intercellular Communication | Acquired limbal stem cell deficiency (LSCD) describes a condition in which the corneal limbal stem cells are altered or destroyed, typically due to ocular trauma, chronic allergy or inflammation. | 28336223 |
| Inflammation, Chronic disease | Altered Intercellular Communication | Serum high-sensitivity CRP is a marker of inflammation and an independent predictor of chronic diseases. | 28336391 |
| Inflammation | Altered Intercellular Communication | Remnant particles accumulate in the arterial wall, potentially propagating local and systemic inflammation. | 28336558 |
| Inflammation, Dysautonomia, Familial, Hyperlipoproteinemia Type III | Altered Intercellular Communication | We evaluated the impact of remnant cholesterol on arterial wall inflammation, circulating monocytes, and bone marrow in patients with familial dysbetalipoproteinemia (FD). | 28336558 |
| Inflammation | Altered Intercellular Communication | Arterial wall inflammation and bone marrow activity were measured using 18F-FDG PET/CT. | 28336558 |
| Inflammation, Dysautonomia, Familial | Altered Intercellular Communication | Patients with FD have increased arterial wall and cellular inflammation. | 28336558 |
| Communicable Diseases, Pneumonitis | Altered Intercellular Communication | Specific depletion of neutrophils in vivo using a mAb and simultaneous infection with HMPV exhibited higher levels of inflammatory cytokines, pulmonary inflammation, and severe clinical disease compared with HMPV-infected, competent mice. | 28336678 |
| Communicable Diseases, Pneumonitis | Altered Intercellular Communication | The absence of gd T cells during HMPV infection led to reduced pulmonary inflammation. | 28336678 |
| Inflammation | Altered Intercellular Communication | ER has been shown to be beneficial in disease prevention and it reduces chronic inflammation. | 28337029 |
| Neurodegenerative Disorders, Inflammation | Altered Intercellular Communication | Chronic inflammation significantly contributes to the pathogenesis of several neurodegenerative disorders. | 28337659 |
| Neurodegenerative Disorders, Inflammation, MS gene | Altered Intercellular Communication | Similar results have also been demonstrated in patients of multiple sclerosis (MS), a neurodegenerative disease characterized by persisting inflammation. | 28337659 |
| Inflammation | Altered Intercellular Communication | The dysregulation of the A20 pathway could then contribute to the persistence of inflammation in these disorders. | 28337659 |
| Delirium, Cognitive problems | Altered Intercellular Communication | Long-Term Self-Reported Cognitive Problems After Delirium in the Intensive Care Unit and the Effect of Systemic Inflammation. | 28338222 |
| Delirium, Inflammation, Cognitive problems | Altered Intercellular Communication | To describe the association between intensive care unit (ICU) delirium and self-reported cognitive problems in 1-year ICU survivors, and investigate whether this association was altered by exposure to systemic inflammation during ICU stay. | 28338222 |
| Delirium, Inflammation | Altered Intercellular Communication | The cumulative exposure to systemic inflammation did not alter this association, suggesting that delirium in the context of little inflammation is also detrimental. | 28338222 |
| Inflammation, Cystitis, Bladder pain | Altered Intercellular Communication | However, absolute cessation of ketamine is the key to success in KC treatment.Key words: Ketamine-induced cystitis, augmentation enterocystoplasty, bladder pain, contracted bladder, inflammation, surgery. | 28339443 |
| Inflammation, Bipolar Disorder | Altered Intercellular Communication | Telomere Length, Oxidative Stress, Inflammation and BDNF Levels in Siblings of Patients with Bipolar Disorder: Implications for Accelerated Cellular Aging. | 28339618 |
| Inflammation, Pain Distress Question | Altered Intercellular Communication | Associations were not attenuated with adjustment for systemic inflammation or pain. | 28340012 |
| Refractory anemias, Inflammation | Altered Intercellular Communication | mtDNA in RA SF was correlated with systemic inflammation as assessed by CRP concentrations. | 28340056 |
| Granulomatous inflammation, Myositis | Altered Intercellular Communication | Three cases of inflammatory myopathy with abundant macrophages (IMAM), 8 cases of granulomatous inflammation and 23 other deltoid muscle biopsies used as controls were all negative. | 28340105 |
| Pharyngeal Carcinoma, Inflammation | Altered Intercellular Communication | Diet and inflammation have been suggested to be important risk factors for oral and pharyngeal cancer. | 28340515 |
| Inflammation, Asthma | Altered Intercellular Communication | Association of systemic inflammation, adiposity, and metabolic dysregulation with asthma burden among Hispanic adults. | 28340865 |
| Inflammation, Obesity | Altered Intercellular Communication | Adiposity, metabolic dysregulation, and inflammation are all implicated in pathogenesis of obesity-related asthma, but their independent contributions are poorly understood. | 28340865 |
| Symptoms, Inflammation, No metabolic abnormalities | Altered Intercellular Communication | To examine the independent contributions of body fat distribution, metabolic abnormalities and inflammation on asthma symptoms and pulmonary function among Hispanics. | 28340865 |
| Hemorrhage | Altered Intercellular Communication | Indications for conversion included severe inflammation/adhesion (n = 31, 46.3%), difficult anatomy (n = 14, 20.9%) and bleeding (n = 6, 9.0%). | 28340928 |
| Hepatitis C, Hepatitis, FAM126A gene | Altered Intercellular Communication | The HCC risk increases with the severity of liver inflammation, and the clinical course of HCV infection depends on a balance between pro- and anti-inflammatory cytokines. | 28340949 |
| Inflammation, Lymphohistiocytosis, Hemophagocytic, Post-transplant lymphoproliferative disorder | Altered Intercellular Communication | Anti-CD20-based chemo-immunotherapeutic regimens have been suggested to assist in the management of Epstein-Barr virus (EBV)-induced hemophagocytic lymphohistiocytosis (HLH) and EBV-associated post-transplant lymphoproliferative disorders (EBV-PTLD), by reducing EBV viral load and EBV-induced inflammation. | 28340951 |
| Airway structure, Respiratory Hypersensitivity, Eosinophilic inflammation | Altered Intercellular Communication | Asthma is the chronic inflammation of airways characterized by eosinophilic infiltration, mucus overproduction, airway hyper-responsiveness and airway remodeling. | 28341820 |
| Post-Traumatic Stress Disorder | Altered Intercellular Communication | Exploring the Link Between Posttraumatic Stress Disorder and inflammation-Related Medical Conditions: An Epidemiological Examination. | 28342139 |
| Post-Traumatic Stress Disorder | Altered Intercellular Communication | These findings suggest a complex link between PTSD and inflammation-related medical conditions. | 28342139 |
| Pancreatitis, Acute, Inflammation | Altered Intercellular Communication | The expression and activation of the AIM2 inflammasome correlates with inflammation and disease severity in patients with acute pancreatitis. | 28342645 |
| Single organ dysfunction, Inflammation, Pancreatitis | Altered Intercellular Communication | Our data demonstrates that AIM2 inflammasome expression and activation is increased early during the course of acute pancreatitis, and suggests that AIM2 activation may affect systemic inflammation and organ failure in these patients. | 28342645 |
| Inflammation, Primary malignant neoplasm | Altered Intercellular Communication | Nutritional interventions aimed at reducing inflammation (INF) may contribute to reduced cancer recurrence risk, but studies have been limited to animal models. | 28342988 |
| Inflammation | Altered Intercellular Communication | Furthermore, their expression of FcRL4 and their enrichment in the IgA isotype points towards a potential role for these cells in the link between mucosal and joint inflammation. | 28343748 |
| Dilated Cardiomyopathy Pathway, Myocarditis, Hypertrophy | Altered Intercellular Communication | Neural cell adhesion molecule expression in dilated cardiomyopathy is associated with intramyocardial inflammation and hypertrophy. | 28343767 |
| Doctor of Chiropractic, Dilated Cardiomyopathy Pathway | Altered Intercellular Communication | Chronic intramyocardial inflammation (inflammatory cardiomyopathy/DCMi) is linked to the pathogenesis of dilated cardiomyopathy (DCM). | 28343767 |
| Inflammation, Venous Thromboembolism, Thrombophilia, Endothelial dysfunction, vinyltriethoxysilane | Altered Intercellular Communication | Polyunsaturated fatty acids (PUFAs) take part in various biological events linked to the pathogenesis of venous thromboembolism (VTE), including inflammation, endothelial dysfunction, and hypercoagulability. | 28344195 |
| Inflammation, Liver Cirrhosis | Altered Intercellular Communication | Inflammation plays a vital role in liver cirrhosis progression and prognosis. | 28345155 |
| Primary malignant neoplasm | Altered Intercellular Communication | The Dietary Inflammatory Index (DII)TM, which was developed to characterize the inflammatory potential of a person's diet, has been shown to be associated with inflammatory conditions such as cancer. | 28345504 |
| Inflammation | Altered Intercellular Communication | We found that old monkeys have greater systemic inflammation and poor intestinal barrier function as compared to young monkeys. | 28346561 |
| Inflammatory disorder, Acute appendicitis NOS (disorder), Ulcerative Colitis, Pelvic Inflammatory Disease | Altered Intercellular Communication | Patrinia scabiosifolia Link (PS), a member of the Patrinia genus (Caprifoliaceae family), has traditionally been used in folk medicines to treat various inflammatory diseases such as acute appendicitis, ulcerative colitis, and pelvic inflammation in Korea and other parts of East Asia. | 28347830 |
| Inflammation, Cardiovascular Diseases | Altered Intercellular Communication | Chronic inflammation associates with increased senescence, which is a strong predictor for cardiovascular disease. | 28347991 |
| Inflammation, Cardiovascular Diseases, Gout | Altered Intercellular Communication | We hypothesised that inflammation accelerates senescence and thereby enhances the risk of cardiovascular disease in gout. | 28347991 |
| Inflammation, Endothelial dysfunction | Altered Intercellular Communication | Alcohol and red wine consumption, but not fruit, vegetables, fish or dairy products, are associated with less endothelial dysfunction and less low-grade inflammation: the Hoorn Study. | 28349255 |
| Inflammation, Endothelial dysfunction, Cyclophosphamide/Vincristine/Dacarbazine Regimen, Cardiovascular Diseases | Altered Intercellular Communication | Endothelial dysfunction and low-grade inflammation are key phenomena in the pathobiology of cardiovascular disease (CVD). | 28349255 |
| Inflammation, Endothelial dysfunction | Altered Intercellular Communication | We investigated the associations between the above food groups and endothelial dysfunction and low-grade inflammation in a population-based cohort of Dutch elderly individuals. | 28349255 |
| Inflammation | Altered Intercellular Communication | Only red wine consumption was associated with a lower low-grade inflammation biomarker score [-0.18 (-0.33; -0.04)]. | 28349255 |
| Inflammation, Dyslipidemias, Myocardial Ischemia, Diabetes Mellitus, Hypertension, CTCAE | Altered Intercellular Communication | Age 62 (range 56-66) cardiometabolic outcomes included hypertension, diabetes, dyslipidemia, inflammation, and ischemic heart disease. | 28349665 |
| Inflammation, Hypertension, CTCAE, Dyslipidemias, Diabetes Mellitus | Altered Intercellular Communication | Accelerated (quadratic) BMI slope was significantly associated with greater risk for hypertension, diabetes, dyslipidemia, and inflammation; odds ratios ranged from 1.93 (diabetes) to 3.15 (dyslipidemia). | 28349665 |
| Inflammation, Colorectal Carcinoma, Malignant Neoplasms | Altered Intercellular Communication | Chronic inflammation increases the risk of development of various cancers, including colorectal cancer. | 28349833 |
| Inflammation, Colorectal Neoplasms, Colorectal Carcinoma | Altered Intercellular Communication | Interleukin-6 has been described as a key regulator of colorectal cancer development and is important in the process of colorectal tumorigenesis largely through the regulation of tumor-promoting inflammation. | 28349833 |
| Inflammation | Altered Intercellular Communication | Systemic inflammation is increased in patients who develop ICU-acquired weakness compared with patients who do not develop ICU-acquired weakness in the first 4 days after ICU admission. | 28350642 |
| Achalasia, Inflammation, Weight decreased, Ulcer | Altered Intercellular Communication | Severe inflammation, ulcers, achalasia, and neoplasias were considered clinically significant endoscopic findings (CSEF) that could explain weight loss. | 28350752 |
| Sepsis, Inflammation, Obstruction of biliary tree, Neoplasms | Altered Intercellular Communication | The aetiology of the neuroendocrine tumors is unclear; in most cases, inflammation of the bile ducts may be the underlying cause and for this reason, the initial patient's evaluation should be focused on the different aspects concerning the oncological one and the possible sequelae of the biliary obstructions that can evolve in biliary sepsis. | 28350976 |
| Adenocarcinoma of prostate, Benign prostatic hypertrophy | Altered Intercellular Communication | Dying for love: Perimenopausal degeneration of vaginal microbiome drives the chronic inflammation-malignant transformation of benign prostatic hyperplasia to prostatic adenocarcinoma. | 28351489 |
| Inflammation, Prostate carcinoma, Benign prostatic hypertrophy | Altered Intercellular Communication | The recent demonstration that far from being benign, "benign" prostatic hypertrophy is a likely a reaction of the prostate to chronic untreated lower genital tract infection, and that this chronic inflammation is likely the usual precursor to the frequent occurrence of prostatic carcinoma has far reaching implications. | 28351489 |
| Inflammation, Malignant neoplasm of prostate | Altered Intercellular Communication | Hence the major hypothesis is that prostatic cancer may arise due to chronic infection and inflammation in the prostate gland consequent upon the altered microbiome of the menopausal female genital tract. | 28351489 |
| Painful intercourse female, Inflammation | Altered Intercellular Communication | It suggests that male dyspareunia, although almost never encountered in clinical practice may in fact be relatively common in older males, and in particular if diagnosed, represents a critical opportunity for therapeutic intervention to interrupt the chronic inflammation - cancer transformation and progression which has been well documented in other tissues. | 28351489 |
| Inflammation, Cardiovascular Diseases | Altered Intercellular Communication | Numerous studies have found that risk of cardiovascular diseases is associated with increased blood levels of circulating markers of systemic inflammation. | 28351806 |
| Unknown (origin) (qualifier value) | Altered Intercellular Communication | Clinical information and histology were reviewed and cases were classified into three groups: Group 1: IgG4-RD orbital inflammation (n=43); Group 2: idiopathic OID (n=12) and Group 3: autoimmune OID (n=14). | 28351925 |
| Unknown (origin) (qualifier value) | Altered Intercellular Communication | Significant elevations of serum IgG2 and tissue IgG2 plasma cells are present in orbital IgG4-RD in comparison with non-IgG4 orbital inflammation (idiopathic and autoimmune OID), suggesting that IgG2 may play a role in IgG4-RD. | 28351925 |
| Communicable Diseases, Eosinophilic peritonitis, Inflammation, Irritation | Altered Intercellular Communication | Eosinophilic peritonitis in a continuous ambulatory peritoneal dialysis patient: Inflammation and irritation without infection. | 28352028 |
| ARCN1 gene, Inflammation | Altered Intercellular Communication | Positive correlation of airway resistance and serum asymmetric dimethylarginine level in COPD patients with systemic markers of low-grade inflammation. | 28352168 |
| ARCN1 gene, Chronic Obstructive Airway Disease, Airway structure | Altered Intercellular Communication | The major feature of COPD is a progressive airflow limitation caused by chronic airway inflammation and consequent airway remodeling. | 28352168 |
| Inflammation, Fibrosis Assessment | Altered Intercellular Communication | Modified arginase and nitric oxide synthase (NOS) pathways are presumed to contribute to the inflammation and fibrosis. | 28352168 |
| ARCN1 gene, Inflammation | Altered Intercellular Communication | Positive correlation of Raw with ADMA in COPD patients showing evidence of a systemic low-grade inflammation implies that ADMA contributes to the progression of COPD, probably by shunting L-arginine from the NOS pathway to the arginase one. | 28352168 |
| TNF protein, human, Inflammation | Altered Intercellular Communication | VP patients had a systemic inflammation response involving IL-6, TNF-a, and MCP-1 which may be due to virus-induced activation of macrophages. | 28352642 |
| hepcidin | Altered Intercellular Communication | HFR achieved a greater reduction in Hepcidin-25 levels than both LFBD [-72% (95% CI: -11 to -133), p = 0.022] and HFBD [-137% (95% CI: -2 to -272), p = 0.047], conceivably due to both a greater removal (because of its convective/adsorptive component) and a lower inflammation-related Hepcidin-25 production. | 28353202 |
| Inflammation, Endothelial dysfunction | Altered Intercellular Communication | Furthermore, endothelial dysfunction appears inversely related to the degree of inflammation in HIV+ patients as measured by IL-6. | 28353539 |
| ANOPHTHALMIA AND PULMONARY HYPOPLASIA, Pancreatic carcinoma | Altered Intercellular Communication | Different inflammation-based scores such as the neutrophil/lymphocyte ratio (NLR), the Odonera Prognostic Nutritional Index (PNI), the Glasgow Prognostic Score, the platelet/lymphocyte ratio, and the C-reactive protein/albumin ratio have been found to be significantly associated with pancreatic cancer (PDAC) prognosis. | 28353661 |
| Inflammation, Bacterial Infections | Altered Intercellular Communication | Recently, a number of diseases were found to be attributed to bacterial infections, resulting in low-grade inflammation and progressive matrix disturbance. | 28355086 |
| Bone necrosis, Myositis | Altered Intercellular Communication | In addition to displaying muscle inflammation, STIR-WBMRI can efficiently detect early multifocal osteonecrosis in the whole bodies of patients with PM/DM. | 28355130 |
| Inflammation, Damage, Chronic Kidney Diseases | Altered Intercellular Communication | Especially in the early phase, CKD is associated with silently ongoing renal damage and inflammation. | 28355260 |
| Liver carcinoma | Altered Intercellular Communication | Inflammation scores predict the survival of patients with hepatocellular carcinoma who were treated with transarterial chemoembolization and recombinant human type-5 adenovirus H101. | 28355305 |
| FAM126A gene | Altered Intercellular Communication | The NLR-PLR score is a more powerful predictive system than the other inflammation-based scores for patients with HCC who were treated with TACE and H101. | 28355305 |
| Inflammation, Atrial Fibrillation by ECG Finding | Altered Intercellular Communication | Accumulating evidence links inflammation and atrial fibrillation (AF). | 28355442 |
| Inflammation | Altered Intercellular Communication | To assess whether markers of systemic and atrial inflammation are associated with incident AF in the general population. | 28355442 |
| Inflammation, Chronic disease | Altered Intercellular Communication | It is assumed that both social stress and chronological age increase the risk of chronic illness, in part, through their effect on systemic inflammation. | 28356188 |
| Inflammation | Altered Intercellular Communication | Limited Presence of IL-22 Binding Protein, a Natural IL-22 Inhibitor, Strengthens Psoriatic Skin Inflammation. | 28356382 |
| Inflammation | Altered Intercellular Communication | Among them, IL-22 largely contributes to epithelial remodeling and inflammation through inhibiting the terminal differentiation of keratinocytes and inducing antimicrobial peptides and selected chemokines. | 28356382 |
| Inflammation, Inflammatory disorder | Altered Intercellular Communication | In chronic inflammatory disorders, unabated inflammation has been associated with a break in innate immune tolerance to self-DNA. | 28356384 |
| Cessation of life, Inflammation | Altered Intercellular Communication | IL-26 expressed in inflammatory lesions confers proinflammatory properties to DNA released by dying cells, setting up a positive amplification loop between extensive cell death and unabated inflammation. | 28356384 |
| Inflammation, Depression, CTCAE, Bipolar Disorder | Altered Intercellular Communication | Background: Low-grade chronic inflammation, which can be modulated by diet, has been suggested as an important risk factor for depression, but few studies have investigated the association between the inflammatory potential of the diet and depression.Objective: We investigated the prospective association between the inflammatory potential of the diet, measured by the Dietary Inflammatory Index (DII), and incident depressive symptoms and tested the potential modulating effect of sex, age, physical activity, and smoking status.Methods: This study included 3523 participants (aged 35-60 y) from the SU.VI.MAX (Supplementation en Vitamines et Mineraux Antioxydants) cohort, who were initially free of depressive symptoms. | 28356432 |
| Inflammation, Tissue injury | Altered Intercellular Communication | The resolution of inflammation is an active process orchestrated by specialized proresolving lipid mediators (SPM) that limit the host response within the affected tissue; failure of effective resolution may lead to tissue injury. | 28356517 |
| Inflammatory Bowel Diseases, CDISC Integrated Basic Data Structure Dataset, SCAPULOPERONEAL MYOPATHY, X-LINKED DOMINANT, Gastrointestinal inflammation | Altered Intercellular Communication | Because persistence of inflammatory signals is a main feature of chronic inflammatory conditions, including inflammatory bowel diseases (IBDs), herein we investigate expression and functions of SPM in intestinal inflammation. | 28356517 |
| Colitis | Altered Intercellular Communication | Systemic treatment with protectin (PD)1n-3 DPA or resolvin (Rv)D5n-3 DPA protected against colitis and intestinal ischemia/reperfusion-induced inflammation in mice. | 28356517 |
| Gastrointestinal inflammation, Colitis | Altered Intercellular Communication | Inhibition of 15-lipoxygenase activity reduced PD1n-3 DPA and augmented intestinal inflammation in experimental colitis. | 28356517 |
| Inflammatory Bowel Diseases, CDISC Integrated Basic Data Structure Dataset, SCAPULOPERONEAL MYOPATHY, X-LINKED DOMINANT, Gastrointestinal inflammation | Altered Intercellular Communication | Because persistence of inflammatory signals is a main feature of chronic inflammatory conditions, including inflammatory bowel diseases (IBDs), herein we investigate expression and functions of SPM in intestinal inflammation. | 28356517 |
| Inflammatory Bowel Diseases, CDISC Integrated Basic Data Structure Dataset, SCAPULOPERONEAL MYOPATHY, X-LINKED DOMINANT, Gastrointestinal inflammation | Altered Intercellular Communication | Because persistence of inflammatory signals is a main feature of chronic inflammatory conditions, including inflammatory bowel diseases (IBDs), herein we investigate expression and functions of SPM in intestinal inflammation. | 28356517 |
| ARCN1 gene, Inflammation, Hypertriglyceridemia | Altered Intercellular Communication | The data from the present study showed that the serum levels of PAI-1 are higher in patients with COPD and that moderate-to-severe airflow limitation, hypertriglyceridemia, and systemic inflammation are independent predictors of an elevated PAI-1 level. | 28356730 |
| Cardiac Hypertrophy, Fibrosis Assessment, Inflammation, Heart failure | Altered Intercellular Communication | Wnt signaling is dysregulated in heart failure (HF) and may promote cardiac hypertrophy, fibrosis, and inflammation. | 28357477 |
| Fibrosis Assessment, Myocarditis | Altered Intercellular Communication | Wnt5a induces IL-6 and TIMP-1 in cardiac fibroblasts, which might promote myocardial inflammation and fibrosis, and thereby contribute to HF progression. | 28357477 |
| Fibrosis Assessment, Myocarditis | Altered Intercellular Communication | * Wnt5a-mediated effects might promote myocardial inflammation and fibrosis, and thereby contribute to HF progression. | 28357477 |
| Inflammation, Malignant Neoplasms | Altered Intercellular Communication | Histopathological analysis revealed malignancy in three cases, non-specific inflammation in two cases, and normal bone in two cases. | 28357575 |
| Inflammation, Obstruction, Traumatic injury, Irritation | Altered Intercellular Communication | Vallecular cysts are formed when the duct of a mucous gland or lingual tonsillar crypt is dilated owing to obstruction from inflammation, irritation, or trauma. | 28357610 |
| Inflammation, Pneumonia | Altered Intercellular Communication | Pneumonia and inflammation in acute decompensated heart failure: a registry-based analysis of 1939 patients. | 28357890 |
| Inflammation, Pneumonia | Altered Intercellular Communication | The prognostic impact of pneumonia and signs of systemic inflammation in patients with acute decompensated heart failure (ADHF) has not been fully elucidated yet. | 28357890 |
| Inflammation, Pneumonia | Altered Intercellular Communication | The aim of the present study was thus to investigate the association of pneumonia and the inflammation surrogate C-reactive protein with all-cause mortality in patients admitted for ADHF. | 28357890 |
| Inflammation, Pneumonia | Altered Intercellular Communication | However, inflammation in general seems to be more important than pneumonia itself for long-term prognosis. | 28357890 |
| Inflammation | Altered Intercellular Communication | Simple and cheap anthropometric indices such as BAI and WHR may be better predictors of low-grade inflammation than VAI in elderly women with SO. | 28358295 |
| Sepsis, Inflammation | Altered Intercellular Communication | In particular, Gram-negative bacilli (GNB), which induce significant inflammation and consequent multiple organ failure, are the etiological bacterial agent in 40% of severe sepsis cases. | 28358803 |
| Inflammation, Stomach Carcinoma | Altered Intercellular Communication | Impact of systemic inflammation on gastric cancer outcomes. | 28358923 |
| Inflammatory abnormality of the eye, Visual disturbance | Altered Intercellular Communication | Ocular inflammation is occasionally observed after vaccinations, and most of them resolve without permanent visual disturbances. | 28358967 |
| palladium, Inflammation, Peyronie Disease | Altered Intercellular Communication | Inflammation is mechanistically involved in the development of Peyronie's disease (PD). | 28359407 |
| palladium, Inflammation | Altered Intercellular Communication | IL-6 trans-signaling and PTX3 amplification at the site of inflammation could have a role in pathophysiological mechanisms of PD. | 28359407 |
| Inflammation, Congestive heart failure | Altered Intercellular Communication | As inflammation plays a crucial role in the complex pathophysiology of CHF, we hypothesized that suPAR might be a suitable prognostic biomarker in patients with CHF. | 28359415 |
| Inflammation, Chronic disease | Altered Intercellular Communication | Albumin level is regulated by nutritional intake and inflammation due to chronic disease, which make it a useful part of a preoperative frailty assessment. | 28359793 |
| Hypernatremia, Inflammation, Fibrosis Assessment, Cardiac dysfunction, Aortic Valve Stenosis | Altered Intercellular Communication | Aortic stenosis (AS) is characterized by pressure overload and causes left ventricular (LV) fibrosis and inflammation, two mechanisms that eventually lead to cardiac dysfunction. | 28360193 |
| Inflammation, Fibrosis Assessment | Altered Intercellular Communication | Gal-3 directly correlated with parameters assessing myocardial fibrosis and inflammation in AS patients. | 28360193 |
| Myocardial fibrosis, Inflammation | Altered Intercellular Communication | AS animals presented enhanced cardiac Gal-3 expression, which paralleled higher myocardial fibrosis and inflammation. | 28360193 |
| Inflammation, Cardiac fibrosis | Altered Intercellular Communication | In short-term AS, the increase in myocardial Gal-3 expression was associated with cardiac fibrosis and inflammation, alterations that were prevented by Gal-3 blockade. | 28360193 |
| Inflammation, Arteriosclerosis | Altered Intercellular Communication | We retrospectively analyzed 33 biomarkers from different pathophysiological domains (inflammation, oxidative stress, remodeling, cardiac stretch, angiogenesis, arteriosclerosis, and renal function) in 460 HF patients (21% HFpEF, left ventricular ejection fraction >=45%) measured at discharge after hospitalization for acute HF. | 28360225 |
| Inflammation | Altered Intercellular Communication | Linear regression followed by network analyses revealed prominent inflammation and angiogenesis-associated interactions in HFpEF and mainly cardiac stretch-associated interactions in HFrEF. | 28360225 |
| Inflammation | Altered Intercellular Communication | In HFpEF, inflammation and angiogenesis-mediated interactions are predominantly observed, while stretch-mediated interactions are found in HFrEF. | 28360225 |
| Inflammation | Altered Intercellular Communication | Erythrocyte concentrations of B1, B2, B6 but not plasma C and E are reliable indicators of nutrition status in the presence of systemic inflammation. | 28361748 |
| Inflammation, Malnutrition | Altered Intercellular Communication | Malnutrition is a strong predictor of mortality on hemodialysis patients, especially when it is associated with inflammation. | 28361749 |
| Inflammation, Malnutrition | Altered Intercellular Communication | Malnutrition Inflammation Score (MIS) is a simple and low cost tool which assesses the presence of malnutrition associated with inflammation. | 28361749 |
| Inflammation, Diabetes Mellitus, Non-Insulin-Dependent | Altered Intercellular Communication | Systemic inflammation and family history in relation to the prevalence of type 2 diabetes based on an alternating decision tree. | 28361994 |
| Inflammation, Diabetes Mellitus, Non-Insulin-Dependent, Diabetes Mellitus | Altered Intercellular Communication | Our study demonstrates that systemic inflammation was proportionally associated with increased prevalence of type 2 diabetes even after adjusting for body mass index, especially in subjects without a family history of diabetes. | 28361994 |
| Inflammatory abnormality of the eye | Altered Intercellular Communication | Plasmapheresis and IVIg may be life-saving and contribute to reduce ocular surface inflammation in TEN. | 28362052 |
| Vasculitis, Coronary Artery Disease, Rheumatism | Altered Intercellular Communication | Inflammatory rheumatic diseases (IRD) are associated with accelerated coronary artery disease (CAD), which may result from both systemic and vascular wall inflammation. | 28362874 |
| Inflammation | Altered Intercellular Communication | Nuclear factor-kappa B (NF-kB) induces the production of inflammatory cytokines and adhesion molecules, which play an essential role in angiogenesis and inflammation. | 28362919 |
| Inflammation, Asthma, Wheezing | Altered Intercellular Communication | Inflammation pathway of asthma and recurrent wheeze are related to eosinophil cells in older children and neutrophil cells in younger children. | 28363401 |
| Inflammation | Altered Intercellular Communication | Systemic inflammation is associated with survival after second-line mTT. | 28363437 |
| Dual-probe in Situ Hybridization, Hyperostosis, Diffuse Idiopathic Skeletal, Calcinosis, Osteogenesis | Altered Intercellular Communication | Diffuse idiopathic skeletal hyperostosis (DISH) is a non-inflammatory condition that involves calcification and ossification of the spinal ligaments and entheses. | 28364275 |
| Inflammation | Altered Intercellular Communication | Ubiquitin-specific protease 14 regulates LPS-induced inflammation by increasing ERK1/2 phosphorylation and NF-kB activation. | 28364380 |
| Inflammation, Cyclophosphamide/Vincristine/Dacarbazine Regimen, Cardiovascular Diseases | Altered Intercellular Communication | To determine whether interdependence in couples' sleep (sleep-wake concordance i.e., whether couples are awake or asleep at the same time throughout the night) is associated with two markers of cardiovascular disease (CVD) risk, ambulatory blood pressure (BP) and systemic inflammation. | 28364457 |
| Inflammation, Sleep Apnea, CTCAE | Altered Intercellular Communication | Objective, but Not Subjective, Sleepiness is Associated With Inflammation in Sleep Apnea. | 28364485 |
| Inflammation, Disease, Osage language | Altered Intercellular Communication | Our findings suggest that OSA with objective EDS is the more severe phenotype of the disorder associated with low-grade inflammation, a link to cardiometabolic morbidity and mortality. | 28364485 |
| Communicable Diseases, Inflammation, Bronchiolitis | Altered Intercellular Communication | Secondary outcomes included overall survival, prevalence of acute rejection, lymphocytic bronchiolitis and infection, lung function, pulmonary and systemic inflammation, and bone mineral density. | 28365177 |
| Orofacial neuropathic pain, Pain Distress Question | Altered Intercellular Communication | 41 patients (73%) of orofacial neuropathic pain patients had a history of pain compatible with an inflammatory condition; 4% (n=2) did not report any prior pain and 23% (n=13) could not remember. | 28365394 |
| Degenerative polyarthritis | Altered Intercellular Communication | Validation of a Knowledge Transfer Tool for the Knee Inflammation MRI Scoring System for Bone Marrow Lesions According to the OMERACT Filter: Data from the Osteoarthritis Initiative. | 28365581 |
| Inflammation, Arthritis | Altered Intercellular Communication | The Relationship Between Cardiac Conduction Times, Cardiovascular Risk Factors, and Inflammation in Patients with Early Arthritis. | 28365582 |
| Inflammation, Arthritis, Conduction disorder of the heart | Altered Intercellular Communication | To investigate the prevalence of conduction disorders in patients with early arthritis and the relationship with inflammation and traditional cardiovascular (CV) risk factors. | 28365582 |
| Inflammation, Arthritis, Conduction disorder of the heart | Altered Intercellular Communication | The prevalence of conduction disorders in patients with early arthritis was 12.5%, which is similar to the general population and was not associated with changes in inflammation markers. | 28365582 |
| Inflammation, Spanish Language, Spondylarthritis | Altered Intercellular Communication | Spondyloarthritis (SpA) is characterized by inflammation and new bone formation and can be treated by inhibition of the proinflammatory cytokines TNF-a and IL-17A. | 28365787 |
| Vitreous Hemorrhage, Inflammation | Altered Intercellular Communication | After treatment, the inflammation subsided but it took 3 months for the vitreous hemorrhage to totally resorb. | 28365853 |
| Inflammation, Chronic Kidney Diseases, Critical Illness, Kidney Diseases | Altered Intercellular Communication | GLP-1 plasma levels were determined in 3 different patient cohorts: 1) critically ill patients admitted to our intensive care unit (n = 215); 2) patients with chronic kidney disease on hemodialysis (n = 173); and 3) a control group (no kidney disease, no acute inflammation, n = 105). | 28366423 |
| Inflammation, Malnutrition, Vascular calcification, Analysis, Chronic Kidney Diseases | Altered Intercellular Communication | Cross-sectional analysis with all men included the Malnutrition, Inflammation and Vascular Calcification cohort, which enrolled consecutive nondialyzed patients with CKD stages 3-5. | 28366446 |
| Inflammation, Rheumatoid Arthritis | Altered Intercellular Communication | The dual regulation of substance P-mediated inflammation via human synovial mast cells in rheumatoid arthritis. | 28366675 |
| Refractory anemias, Inflammation | Altered Intercellular Communication | On the other hand, SP activates MCs to induce inflammatory mediators, suggesting the dual regulation of SP-mediated inflammation by MCs in RA. | 28366675 |
| Inflammation, Cerebral Infarction, Acute Lung Injury, Hemorrhagic, Blood Coagulation Disorders | Altered Intercellular Communication | We determined whether serum MIF concentrations are associated with inflammation, severity, in-hospital major adverse events (IMAEs) (i.e., in-hospital mortality, acute lung injury, acute traumatic coagulopathy, progressive hemorrhagic injury and posttraumatic cerebral infarction) and long-term clinical outcome (i.e., 6-month functional outcome) after TBI. | 28366792 |
| Inflammation, Traumatic injury | Altered Intercellular Communication | Increased serum MIF concentrations have close relation to inflammation, trauma severity and clinical outcomes, substantializing MIF as a good prognostic biomarker after TBI. | 28366792 |
| Inflammation, Heart failure, Diabetes Mellitus | Altered Intercellular Communication | Inflammation plays an important role in heart failure and diabetes mellitus. | 28367848 |
| Inflammation, Pancreatitis, Endothelial dysfunction | Altered Intercellular Communication | In severe acute pancreatitis (SAP), systemic inflammation leads to endothelial dysfunction and activation of coagulation. | 28368336 |
| Postprandial Period, Endotoxemia, Cardiovascular Diseases | Altered Intercellular Communication | Postprandial inflammation and endotoxaemia are determinants of cardiovascular and metabolic disease risk which are amplified by high fat meals. | 28368340 |
| Postprandial Period, Endotoxemia | Altered Intercellular Communication | We aimed to examine the determinants of postprandial inflammation and endotoxaemia in older and younger adults following a high fat mixed meal. | 28368340 |
| Inflammatory Bowel Diseases, Tumor necrosis, Gastrointestinal inflammation | Altered Intercellular Communication | Oncostatin M drives intestinal inflammation and predicts response to tumor necrosis factor-neutralizing therapy in patients with inflammatory bowel disease. | 28368383 |
| Gastrointestinal inflammation, Colitis | Altered Intercellular Communication | In an animal model of anti-TNF-resistant intestinal inflammation, genetic deletion or pharmacological blockade of OSM significantly attenuates colitis. | 28368383 |
| Inflammatory Bowel Diseases, Crohn Disease, Ulcerative Colitis | Altered Intercellular Communication | Inflammatory bowel diseases (IBD), including Crohn's disease (CD) and ulcerative colitis (UC), are complex chronic inflammatory conditions of the gastrointestinal tract that are driven by perturbed cytokine pathways. | 28368383 |
| Inflammation, Biliary calculi | Altered Intercellular Communication | A total of 149 patients (120 female and 29 male) diagnosed with gallstones who underwent cholecystectomy and who did not have symptoms of acute inflammation were included. | 28368860 |
| Communicable Diseases, Inflammation, Calculi | Altered Intercellular Communication | The presence of gingival inflammation, calculus, and infectious dental diseases did not significantly differ between groups. | 28369398 |
| ARCN1 gene, Chronic Obstructive Airway Disease | Altered Intercellular Communication | Chronic obstructive pulmonary disease (COPD) is a corticosteroid-resistant airway inflammatory condition. | 28369685 |
| Immune thrombocytopenic purpura, Bronchiectasis, Granulomatous inflammation, Splenomegaly, Lymphadenopathy, Grade 1 Non-Infectious Wound Complication, CTCAE | Altered Intercellular Communication | The prevalence of non-infectious complications was similar to that of previously reported cohorts: bronchiectasis (35.8%), splenomegaly (22.4%), lymphadenopathy (26.3%), granulomatous inflammation (3.9%) and idiopathic thrombocytopenic purpura (14.5%). | 28370285 |
| Inflammation | Altered Intercellular Communication | The innate immune system, which includes toll-like receptor (TLR) signaling, plays an important role in inflammation and oncogenesis. | 28370778 |
| Inflammation, Bacteriuria | Altered Intercellular Communication | Asymptomatic bacteriuria is not a modifiable risk factor for chronic inflammation in the MHD population. | 28370973 |
| Inflammation, Joint Subluxations, Communicable Diseases, ACAA1 gene, Brain Concussion | Altered Intercellular Communication | Primary teeth with concussion or subluxation injury carry a low risk of PN and infection with periapical inflammation, root resorption, and PTL. | 28371334 |
| physiopathological | Altered Intercellular Communication | These results could explain some of the mechanisms of vascular dysfunction reported in inflammatory conditions. | 28373136 |
| Inflammation | Altered Intercellular Communication | In conclusion, IL-4 signaling plays a crucial role in the regulatory functions of SOCS1 in apoptosis and inflammation in human osteoarthritic chondrocytes. | 28373981 |
| Inflammation | Altered Intercellular Communication | Macrophages, chondrocytes, osteoblasts and osteoclasts express inducible NOS (iNOS) at the site of synovial inflammation. | 28374504 |
| Inflammation, White matter | Altered Intercellular Communication | PRDX2 was found to be upregulated in white matter MS lesions mainly in astrocytes, and its expression level was positively correlated with the degree of inflammation and oxidative stress. | 28375164 |
| Inflammation, Chronic Kidney Diseases | Altered Intercellular Communication | Chronic kidney disease (CKD) is a progressive disease with an inverse relationship between kidney function and levels of inflammation and oxidative stress. | 28375641 |
| Inflammation, Chronic Kidney Diseases | Altered Intercellular Communication | Further studies are needed to determine whether curcumin and B. serrata may be effective means to reduce inflammation in patients with CKD. | 28375641 |
| Inflammation, Malignant Neoplasms | Altered Intercellular Communication | Inflammation has been linked with development of some cancers. | 28376082 |
| Inflammation, Colorectal Carcinoma | Altered Intercellular Communication | Prediagnostic systemic inflammation may impact colorectal cancer incidence and survival; therefore, prompting investigations linking inflammatory pathways preceding colorectal cancer with disease severity and progression. | 28376082 |
| Inflammation, Autonomic nervous system disorders, Atherosclerosis | Altered Intercellular Communication | The association between autonomic dysfunction, inflammation and atherosclerosis in men under investigation for carotid plaques. | 28376102 |
| Inflammation, Autonomic nervous system disorders, Atherosclerosis | Altered Intercellular Communication | In this study we hypothesized that autonomic dysfunction increases inflammation, which subsequently accelerates atherosclerosis. | 28376102 |
| Inflammation, Atherosclerosis | Altered Intercellular Communication | The aim of the current study was to investigate the association between autonomic tone, inflammation and atherosclerosis. | 28376102 |
| Inflammation, Atherosclerosis | Altered Intercellular Communication | To investigate if inflammation could provide a link between autonomic function and carotid atherosclerosis we adjusted the associations accordingly. | 28376102 |
| Inflammation, Dental Plaque, Atherosclerosis | Altered Intercellular Communication | After adjusting for WBCC and CRP the inverse association between BRS and carotid plaque area was attenuated and did not remain significant, while both WBCC and CRP remained significantly associated with carotid plaque area, indicating that low-grade inflammation can possibly link BRS to atherosclerosis. | 28376102 |
| Inflammation, Autonomic nervous system disorders, Atherosclerosis | Altered Intercellular Communication | We demonstrate that autonomic dysfunction is associated with atherosclerosis and that inflammation could play an important role in mediating this relationship. | 28376102 |
| Inflammation, Chronic sinusitis | Altered Intercellular Communication | Correlation of Symptoms, Clinical Signs, and Biomarkers of Inflammation in Postsurgical Chronic Rhinosinusitis. | 28376637 |
| Inflammation, Pain Distress Question | Altered Intercellular Communication | Mucosal inflammation identified on nasal endoscopy was positively correlated with congestion ( P < .028), runny nose ( P < .002), and ear pain ( P < .007). | 28376637 |
| Inflammation, Rhinorrhea, Craniosynostosis | Altered Intercellular Communication | Nasal endoscopy, not CT imaging, has the strongest correlation with the 2 cardinal symptoms of congestion and runny nose in CRS patients; these correlate with biomarkers of eosinophilic inflammation. | 28376637 |
| Hemangioma, Cavernous, Inflammation, Microbleeds, Malignant Neoplasms | Altered Intercellular Communication | We conclude that, although rare, rapid expansion of an existing cavernoma should be considered suspicious for the development of other malignant tumors, and propose adding chronic inflammation in the surrounding brain caused by microbleeds and hemosiderin deposition from the cavernoma to the list of possible causes. | 28377258 |
| Inflammation, Chronic Kidney Diseases | Altered Intercellular Communication | CONCLUSIONS We postulate that PTX3 might be an early marker of CV mortality in patients with advanced CKD yet before the increase of specific marker for systemic inflammation like hsCRP. | 28377558 |
| Inflammation | Altered Intercellular Communication | The biopsy slides showed suppurative granulomatous inflammation affecting greater than 50% of the parenchymal lung surface. | 28377567 |
| Inflammation, Chronic disease | Altered Intercellular Communication | Apigenin can attenuate inflammation, which is associated with many chronic diseases of aging. | 28378188 |
| Inflammation, Injury of liver | Altered Intercellular Communication | Acute-phase inflammation plays a critical role in liver graft injury. | 28378341 |
| Inflammation, Injury of liver | Altered Intercellular Communication | Our data demonstrated that NLRP3 inflammasomes, activated by the RAP1/KC axis, played a critical role in initiating inflammation during the early stage of liver graft injury. | 28378341 |
| Inflammation, Venous Insufficiency | Altered Intercellular Communication | Objective Inflammation has been implicated as a factor that may contribute to chronic venous insufficiency. | 28379059 |
| Degenerative polyarthritis, Inflammation | Altered Intercellular Communication | Inflammation plays a key role in the development and progression of OA both on the side of apoptosis and repair, while its exact role in pathogenesis has yet to be fully elucidated. | 28379175 |
| Inflammation, Damage, Hypertension, CTCAE | Altered Intercellular Communication | Hypertension is a chronic, low-grade inflammation process associated with the release of cytokines and development of target organ damage. | 28380135 |
| Shock, Inflammation | Altered Intercellular Communication | Heat shock proteins (HSPs) are molecular chaperones essential for maintaining cellular functions, but they can act as a danger signal during inflammation. | 28380264 |
| Have Autoimmune or Inflammatory Condition, Primary malignant neoplasm, Neoplasms, S100A4 protein, human | Altered Intercellular Communication | While chronic autoimmune inflammation is considered a potential risk factor for malignant transformation in many solid tumors, the opposite idea that cancer may trigger autoimmune responses remains controversial. | 28381149 |
| Inflammation, Diabetes Mellitus | Altered Intercellular Communication | SUCNR1-mediated chemotaxis of macrophages aggravates obesity-induced inflammation and diabetes. | 28382382 |
| Inflammation, Diabetes Mellitus, Non-Insulin-Dependent, Obesity | Altered Intercellular Communication | Obesity induces macrophages to drive inflammation in adipose tissue, a crucial step towards the development of type 2 diabetes. | 28382382 |
| Inflammation, Diabetes Mellitus, Non-Insulin-Dependent | Altered Intercellular Communication | We therefore investigated whether succinate receptor 1 (SUCNR1) could play a role in the development of adipose tissue inflammation and type 2 diabetes. | 28382382 |
| Inflammation, Infiltration, Obesity | Altered Intercellular Communication | Our results reveal that activation of SUCNR1 in macrophages is important for both infiltration and inflammation of adipose tissue in obesity, and suggest that SUCNR1 is a promising therapeutic target in obesity-induced type 2 diabetes. | 28382382 |
| Inflammation, Mucopolysaccharidosis I | Altered Intercellular Communication | The elevated metabolites are predominantly lipid derivatives, and also include cysteine metabolites and a fibrinogen peptide fragment, consistent with the status of oxidative stress and inflammation in MPS III. | 28382573 |
| Smell Perception, Chronic sinusitis, Craniosynostosis | Altered Intercellular Communication | Chronic rhinosinusitis (CRS) is a common inflammatory condition and a major cause of olfactory loss. | 28383208 |
| Inflammation, Refractory anemias, Autoimmune Diseases, Rheumatoid Arthritis, Hyperplasia | Altered Intercellular Communication | Rheumatoid arthritis (RA) is a systemic autoimmune disease characterized by chronic inflammation and synovial hyperplasia, which usually affects multiple joints. | 28383601 |
| Colorectal Carcinoma | Altered Intercellular Communication | Less increased g-H2AX in UC-CRC compared to CRC gave evidence that colitis-triggered inflammation masks DNA damage, thus contributing to neoplastic transformation. | 28383667 |
| Inflammation, Carcinogenesis | Altered Intercellular Communication | We hypothesize that JNK-dependent cell cycle arrest is important in AUC, while chronic inflammation causes dysregulated JNK activity in quiescent phase that may contribute to checkpoint override, promoting UC carcinogenesis. | 28383667 |
| Refractory anemias, Rheumatoid Arthritis, Inflammation | Altered Intercellular Communication | Rheumatoid arthritis (RA) causes chronic inflammation and alteration of articular tissue and joints. | 28384116 |
| Inflammation | Altered Intercellular Communication | It has been shown that YKL-40 is implicated in tissue remodeling, angiogenesis and inflammation. | 28384116 |
| Pancreatitis, Myocarditis, CTCAE 5.0 | Altered Intercellular Communication | Myocarditis developed and extensive pancreatic inflammation was observed in all mice infected with CB2/04/279 or CVB/O, but not in animals infected with CB2/04/243. | 28384999 |
| hearing impairment, Inflammation, Otitis Media with Effusion | Altered Intercellular Communication | OME is characterized as an inflammation with accumulation of secretion in the tympanic cavity, leading to conductive hearing loss. | 28385090 |
| atherosclerotic | Altered Intercellular Communication | Detection of Atherosclerotic Inflammation by 68Ga-DOTATATE PET Compared to [18F]FDG PET Imaging. | 28385306 |
| atherosclerotic | Altered Intercellular Communication | This study tested the efficacy of gallium-68-labeled DOTATATE (68Ga-DOTATATE), a somatostatin receptor subtype-2 (SST2)-binding PET tracer, for imaging atherosclerotic inflammation. | 28385306 |
| atherosclerotic | Altered Intercellular Communication | We validated 68Ga-DOTATATE PET as a novel marker of atherosclerotic inflammation and confirmed that 68Ga-DOTATATE offers superior coronary imaging, excellent macrophage specificity, and better power to discriminate high-risk versus low-risk coronary lesions than [18F]FDG. | 28385306 |
| Cessation of life, Communicable Diseases, Hemorrhage, Inflammation | Altered Intercellular Communication | Reasons for removal were that PICC was not considered to be useful any longer (16), suspicion of infection (inflammation without documentation) (5) or infection (2), patient's wish (4), death (4), accidental withdrawal (2), puncture site bleeding (1), and catheter change due to extracorporeal photopheresis (1). | 28386787 |
| Inflammation, Obesity | Altered Intercellular Communication | Chemerin is believed to be a mediator for the adipose tissue inflammation that occurs in obesity. | 28387898 |
| Inflammation, Tachycardia by ECG Finding | Altered Intercellular Communication | Attenuation effects of cTnT, tachycardia and CRP suggest that cardiac stress or inflammation may be involved in mechanisms causing frequent PVC i AECOPD. | 28388306 |
| Necrotizing granulomatous inflammation, Neoplasm Metastasis | Altered Intercellular Communication | Biopsies of the left lacrimal gland revealed a silver material with associated chronic granulomatous inflammation and secondary calcification. | 28388345 |
| Inflammation, Malnutrition, Muscle (organ) | Altered Intercellular Communication | The loss of muscle in older (aged >60 years) patients in the ICU may be particularly rapid due to a perfect storm of increased catabolic factors, including systemic inflammation, disuse, protein malnutrition, and reduced anabolic stimuli. | 28388378 |
| Inflammation, Dental Plaque | Altered Intercellular Communication | Plaque neovascularization accompanies local inflammation and critically contributes to plaque instability. | 28388659 |
| Inflammation, Uveomeningoencephalitic Syndrome, Tuberculosis, Uveitis | Altered Intercellular Communication | However, the manifestations of the inflammation were complicated as they included features that could be attributed mainly to Vogt-Koyanagi-Harada (VKH) disease and tuberculous serpiginous-like uveitis. | 28389634 |
| Inflammation | Altered Intercellular Communication | Therefore, a systemic evaluation, together with specific laboratory and paraclinical investigations, were carried out to define the etiology of the inflammation and develop an optimal therapeutic plan. | 28389634 |
| Inflammation, Hyperbilirubinemia | Altered Intercellular Communication | Characteristics of the heme catabolic pathway in mild unconjugated hyperbilirubinemia and their associations with inflammation and disease prevention. | 28389660 |
| Inflammation | Altered Intercellular Communication | Furthermore, acute inflammation was more evident in erosive-ulcerative lesions (p=0.001). | 28390133 |
| vascular inflammations | Altered Intercellular Communication | Circulating leukocyte-derived microparticles act as proinflammatory mediators that reflect vascular inflammation. | 28390251 |
| Inflammation, Primary malignant neoplasm, Coronary Artery Disease | Altered Intercellular Communication | Galectin-3 binding protein (Gal-3BP) has been associated with inflammation and cancer, however, its role in coronary artery disease (CAD) and cardiovascular outcome remains unclear. | 28390290 |
| Pain Distress Question, Inflammation | Altered Intercellular Communication | An escalation in pain was observed in week 3 of treatment possibly as a result of radiation induced inflammation alongside cytotoxic chemotherapy. | 28390539 |
| Inflammation, Lewy Bodies, Parkinson Disease, "Alzheimers Disease", palladium, Presenile dementia, dendritic lamellar body, Data types - Address | Altered Intercellular Communication | Enhanced inflammation has been associated with Alzheimer's disease (AD) and diseases with Lewy body (LB) pathology, such as Parkinson's disease (PD) and dementia with Lewy bodies (DLB). | 28390825 |
| Inflammation, Angular, Data types - Address | Altered Intercellular Communication | One issue is whether amyloid and tangle pathology, features of AD, or a-synuclein LB pathology have similar or different effects on brain inflammation. | 28390825 |
| Inflammation, Intestinal Diseases | Altered Intercellular Communication | Elevated fecal calprotectin (FC) is a non-invasive marker of inflammation indicating bowel disease. | 28391117 |
| Arterial Stiffness, Inflammation, Chronic Kidney Diseases | Altered Intercellular Communication | Inflammation and Arterial Stiffness in Chronic Kidney Disease: Findings From the CRIC Study. | 28391349 |
| Arterial Stiffness, Inflammation, Chronic Kidney Diseases | Altered Intercellular Communication | Inflammation is proposed to have a role in the development of arterial stiffness, and CKD is recognized as a proinflammatory state. | 28391349 |
| Arterial Stiffness, Inflammation, Chronic Kidney Diseases | Altered Intercellular Communication | However, no large scale investigations have examined the impact of inflammation on the progression of arterial stiffness in CKD. | 28391349 |
| Arterial Stiffness, Inflammation | Altered Intercellular Communication | In longitudinal analyses, there were few meaningful correlations between baseline levels of inflammation and changes in metrics of arterial stiffness over time. | 28391349 |
| Arterial Stiffness, Inflammation, Chronic Kidney Diseases | Altered Intercellular Communication | In a large cohort of CKD participants, we observed multiple significant correlations between initial markers of inflammation and metrics of arterial stiffness, but baseline inflammation did not predict changes in arterial stiffness over time. | 28391349 |
| Inflammation | Altered Intercellular Communication | Inflammation and Cyclooxygenase-2 (COX-2) as a part of it are common in BPH specimens and may play a role in the pathogenesis of the disease through cytokines that promote cell growth or lead to smooth muscle contraction. | 28391389 |
| vascular inflammations | Altered Intercellular Communication | Laboratory findings have suggested that systemic and vascular inflammation can impair the antiatherogenic function of high-density lipoproteins (HDLs). | 28391888 |
| Inflammation, HIV | Altered Intercellular Communication | Persistent immune activation and inflammation in virologically suppressed human immunodeficiency virus (HIV) infection are linked to excess cardiovascular risk. | 28391912 |
| Inflammation, HIV Infections | Altered Intercellular Communication | In virologically suppressed individuals with HIV infection, atorvastatin did not significantly decrease levels of soluble or cellular biomarkers of immune activation and inflammation but resulted in robust reductions in LDL cholesterol, oxLDL, and lipoprotein-associated phospholipase A2, biomarkers associated with cardiovascular risk. | 28391912 |
| Inflammation, Neoplasm Metastasis | Altered Intercellular Communication | Although many etiologic models have been explored, secondary damage caused by continued inflammation and iron exposure from red blood cell lysis may explain poor outcomes at distant follow-up. | 28392117 |
| Inflammation, Angina Pectoris | Altered Intercellular Communication | We investigated the relationship between endocan (a marker of systemic inflammation) and the development of coronary collateral circulation (CCC) as evaluated by coronary angiography in patients with chronic stable angina pectoris. | 28393589 |
| Inflammation, Dental Plaque | Altered Intercellular Communication | Efficacy of triphala extract and chlorhexidine mouth rinse against plaque accumulation and gingival inflammation among female undergraduates: A randomized controlled trial. | 28393817 |
| Inflammation, Dental Plaque | Altered Intercellular Communication | To know the efficacy of Triphala extract and Chlorhexidine mouth rinse against plaque and gingival inflammation. | 28393817 |
| Inflammation, Peripheral Arterial Diseases | Altered Intercellular Communication | Inflammation plays an important role in the initiation and progression of peripheral artery disease (PAD). | 28394111 |
| Inflammation, Diabetes Mellitus | Altered Intercellular Communication | Data regarding the prognostic implication of diabetes and inflammation on all-cause mortality in patients with symptomatic PAD and preserved left ventricular ejection fraction (LVEF >50%). | 28394111 |
| Inflammation, Arthritis, Gouty | Altered Intercellular Communication | Genetic variants of PPAR-gamma coactivator 1B augment NLRP3-mediated inflammation in gouty arthritis. | 28394398 |
| Arthritis, Hyperuricemia, Gout | Altered Intercellular Communication | Gout is characterized by recurrent attacks of arthritis with hyperuricaemia and urate crystal-induced inflammation. | 28394398 |
| Inflammation | Altered Intercellular Communication | Although urate transporters are known as risk factors, the immunogenetics of gouty inflammation remains unclear. | 28394398 |
| Inflammation, Arthritis, Gouty | Altered Intercellular Communication | These data suggest that variants of PPARGC1B , a regulator of metabolism and inflammation, contribute to the pathogenesis of gouty arthritis. | 28394398 |
| Inflammation, Fibrosis Assessment, Mast cell infiltration | Altered Intercellular Communication | Non-Hunner-type IC is characterized by severe fibrosis and increased mast cell infiltration, whereas Hunner-type IC is characterized by severe inflammation and urothelial denudation in the entire bladder. | 28394416 |
| Inflammation, Diabetes Mellitus, Non-Insulin-Dependent, Obesity | Altered Intercellular Communication | The gut microbiota affects host lipid and glucose metabolism, satiety, and chronic low-grade inflammation to contribute to obesity and type 2 diabetes. | 28396144 |
| Respiratory Tract Infections, Bronchitis, Pneumonia | Altered Intercellular Communication | In these cases, it was mainly used for postoperative anti-inflammation and treating upper respiratory infection, pneumonia and bronchitis. | 28397057 |
| Chronic otitis | Altered Intercellular Communication | Subjects with chronic otitis media without active inflammation (dry ear) had similar middle ear microbiomes as the normal middle ears group. | 28397271 |
| Proteobacteria, Chronic otitis | Altered Intercellular Communication | Subjects with chronic otitis media with active inflammation (wet ear) had a lower prevalence of Proteobacteria and a higher prevalence of Firmicutes than the normal middle ears. | 28397271 |
| Acute inflammation, Chronic otitis | Altered Intercellular Communication | Alteration of the middle ear microbiome may contribute to the pathogenesis of chronic otitis media with active inflammation. | 28397271 |
| Dysphonia, Laryngitis | Altered Intercellular Communication | This is a retrospective chart review of adult patients with persistent dysphonia plus evidence of laryngeal inflammation who underwent biopsy for culture at a tertiary care medical center. | 28397557 |
| Laryngitis | Altered Intercellular Communication | For MSSA- and MRSA-associated laryngitis, an extended course of antibiotics may be necessary for symptom improvement and resolution of laryngeal inflammation. | 28397557 |
| Inflammation, Carcinogenesis | Altered Intercellular Communication | Chronic inflammation is postulated to be one crucial mechanism for prostate carcinogenesis. | 28398294 |
| Inflammation, Asthma | Altered Intercellular Communication | Serum periostin relates to type-2 inflammation and lung function in asthma: Data from the large population-based cohort Swedish GA(2)LEN. | 28398635 |
| Inflammation, Asthma | Altered Intercellular Communication | Periostin has been suggested as a novel, phenotype-specific biomarker for asthma driven by type 2 inflammation. | 28398635 |
| Colonization | Altered Intercellular Communication | Notable features of CRSwNP are the frequent presence of type 2 allergic inflammation and high prevalence of Staphylococcus aureus (SA) colonization. | 28398769 |
| Epithelial Damage, Inflammation, polyps | Altered Intercellular Communication | As inflammation persists, sinus tissue undergoes epithelial damage and repair along with polyp growth, despite active medical management. | 28398769 |
| Ulcerative Colitis | Altered Intercellular Communication | Ulcerative colitis (UC) is a long-time inflammatory condition arising from aberrant immune activation in the colon and the rectum. | 28398870 |
| Degenerative polyarthritis, Inflammation, Obesity | Altered Intercellular Communication | Risk factors for OA include age and obesity with inflammation identified as a key mediator of disease pathogenesis. | 28399156 |
| Inflammation, Hemorrhage, Obstruction, Meckel Diverticulum | Altered Intercellular Communication | Hemorrhage, obstruction and inflammation are most common complications of Meckel's diverticulum. | 28399839 |
| Inflammation, Gastric Tissue, Perforation (observation) | Altered Intercellular Communication | Perforation was due to progressive inflammation and presence of gastric and pancreatic tissue found on histopathology. | 28399839 |
| Pyelonephritis, Nephritis | Altered Intercellular Communication | Xanthogranulomatous pyelonephritis is a rare and serious manifestation of chronic kidney inflammation that can be life-threatening if not recognized and treated appropriately, often with antibiotics and surgery. | 28399929 |
| Pyelonephritis, Xanthogranulomatous, Inflammation | Altered Intercellular Communication | Based on classic radiographic and histopathologic findings, she was ultimately diagnosed with xanthogranulomatous pyelonephritis of her left kidney, which was a direct consequence of chronic inflammation. | 28399929 |
| Pleural Effusion, CTCAE, Inflammation | Altered Intercellular Communication | This inflammation exhibited spread to local tissues and across her left hemidiaphragm, resulting in a unilateral pleural effusion which explained her chest discomfort. | 28399929 |
| Perforation of rectum, Colorectal Carcinoma | Altered Intercellular Communication | A total of 43 patients with surgically and pathologically confirmed colorectal perforation caused by either colorectal cancer (n =27) or an inflammatory conditions (n = 16) were identified. | 28401282 |
| Esophagitis, Esophageal carcinoma | Altered Intercellular Communication | Clinical significance of the correlation between PLCE 1 and PRKCA in esophageal inflammation and esophageal carcinoma. | 28402280 |
| Inflammation, Primary malignant neoplasm, Carcinoma of lung | Altered Intercellular Communication | To reflect the broader role of inflammation in lung cancer, we examined a large panel of 33 inflammatory proteins in the sera of 129 lung cancer patients selected from the National Cancer Institute-Maryland case-control study. | 28402963 |
| Single organ dysfunction, Pancreatitis, Pancreatitis, Acute | Altered Intercellular Communication | Evaluation of extrapancreatic inflammation on abdominal computed tomography as an early predictor of organ failure in acute pancreatitis as defined by the revised Atlanta classification. | 28403081 |
| Communicable Diseases, Inflammation, Respiratory Tract Infections | Altered Intercellular Communication | Increased respiratory iron content has been associated with respiratory tract infection, though it is unclear if this represents a predisposing factor for infection or the sequelae of inflammation. | 28403845 |
| Inflammation, Carcinogenesis, Neoplasms | Altered Intercellular Communication | CCL4 (C-C chemokine ligand 4), a macrophage inflammatory protein with a key role in inflammation and immune-regulation, was implicated in carcinogenesis by facilitating instability in the tumor environment. | 28404909 |
| Inflammation, Helicobacter pylori | Altered Intercellular Communication | Toll-like receptor (TLR) genes, which play critical roles in Helicobacter pylori induced chronic inflammation, may also be implicated in GC susceptibility. | 28404962 |
| ARCN1 gene, Inflammation | Altered Intercellular Communication | MicroRNA-125a and -b inhibit A20 and MAVS to promote inflammation and impair antiviral response in COPD. | 28405612 |
| Inflammation, Infection | Altered Intercellular Communication | Influenza A virus (IAV) infections lead to severe inflammation in the airways. | 28405612 |
| ARCN1 gene, Chronic Obstructive Airway Disease, Infection, Airway structure | Altered Intercellular Communication | Patients with chronic obstructive pulmonary disease (COPD) characteristically have exaggerated airway inflammation and are more susceptible to infections with severe symptoms and increased mortality. | 28405612 |
| ARCN1 gene, Communicable Diseases, Inflammation | Altered Intercellular Communication | The mechanisms that control inflammation during IAV infection and the mechanisms of immune dysregulation in COPD are unclear. | 28405612 |
| Communicable Diseases, Inflammation | Altered Intercellular Communication | IAV infection increased the expression of miR-125a or -b, which directly reduced the expression of A20 and mitochondrial antiviral signaling (MAVS), and caused exaggerated inflammation and impaired antiviral responses. | 28405612 |
| Refractory anemias, Inflammation | Altered Intercellular Communication | Use of bisphosphonate significantly increased the BMD of the spine in patients over a period of 3 years and was important for maintaining the BMD among patients with RA under the control of inflammation and disease activity. | 28405825 |
| Inflammation, Toxic effect of venom, Scorpion sting, Scorpion Venoms | Altered Intercellular Communication | The pathophysiology of envenomation is related to an excessive inflammatory response; however, no studies have identified the differences in immune responses to scorpion stings and mainly the mechanisms of inflammation between children and adults, which may be a determinant key of the susceptibility of children to scorpion envenomation. | 28405853 |
| Attention deficit hyperactivity disorder | Altered Intercellular Communication | Systemic Inflammation during the First Postnatal Month and the Risk of Attention Deficit Hyperactivity Disorder Characteristics among 10 year-old Children Born Extremely Preterm. | 28405874 |
| Inflammation, Attention deficit hyperactivity disorder | Altered Intercellular Communication | Systemic inflammation during the first postnatal month among children born extremely preterm appears to increase the risk of teacher-identified ADHD characteristics, and high concentrations of proteins with neurotrophic properties appear capable of modulating this increased risk. | 28405874 |
| Inflammation, Atherosclerosis | Altered Intercellular Communication | Our results suggest that the AT of PAD patients infiltrated with macrophages produces more cytokines involved in the development of inflammation and atherosclerosis. | 28406704 |
| Inflammation, Community acquired pneumonia | Altered Intercellular Communication | To explore the performance of the neutrophil-to-lymphocyte ratio (NLR), an index of systemic inflammation that predicts prognosis of several diseases, in a cohort of elderly adults with community-acquired pneumonia (CAP). | 28407209 |
| Biliary hyperplasia, Fibrosis Assessment, Inflammation | Altered Intercellular Communication | Multiple genes related to liver fibrosis, inflammation, and biliary hyperplasia were increased in H19-BDL versus null-BDL mice, whereas genes in BA synthesis were decreased. | 28407375 |
| Inflammation, muscle mass | Altered Intercellular Communication | Is the Body Cell Mass Index (BCMI) a useful prognostic factor to describe nutritional, inflammation and muscle mass status in hospitalized elderly? | 28408051 |
| Inflammation | Altered Intercellular Communication | The good concordance between PAS-II and SDAI supports their use in clinical practice, especially if biomarkers of inflammation or the possibility of joint count are not available. | 28408110 |
| Inflammation, Atherosclerosis | Altered Intercellular Communication | Here we investigated the effects of iNAMPT overexpression in leukocytes on inflammation and atherosclerosis. | 28408371 |
| Inflammation, Immune System Diseases | Altered Intercellular Communication | Bacteria secrete nanometer-sized extracellular vesicles (EVs), which may induce more immune dysfunction and inflammation than the bacteria themselves. | 28408748 |
| Inflammation, Neurologic Deficits, Loss of neurons | Altered Intercellular Communication | Spinal poly-GA inclusions in a C9orf72 mouse model trigger motor deficits and inflammation without neuron loss. | 28409281 |
| Inflammation, Behavior, Prodromal Symptoms | Altered Intercellular Communication | Thus, poly-GA triggers behavioral deficits through inflammation and protein sequestration that likely contribute to the prodromal symptoms and disease progression of C9orf72 patients. | 28409281 |
| Granulomatous inflammation, Lesion of spleen | Altered Intercellular Communication | Endoscopic ultrasound-guided fine needle aspiration of splenic lesion revealed granulomatous inflammation. | 28410696 |
| Inflammation, Osteoporotic Fractures | Altered Intercellular Communication | Chronic inflammation provides the substrate for various mechanisms involved in osteoporotic fracture. | 28411093 |
| Inflammation, Crohn Disease | Altered Intercellular Communication | Vitamin D modulates inflammation in Crohn's disease (CD). | 28412753 |
| Inflammation, Adipose tissue loss | Altered Intercellular Communication | This is particularly evident in big chronic wounds with considerable tissue loss, which become senescent in the process of inflammation or proliferation losing the ability to epithelialize. | 28413063 |
| Coma (genus), Inflammation, Malaria, Cerebral, Vascular occlusion, Cessation of life | Altered Intercellular Communication | Cytoadherence, sequestration, alterations in cytokine expression, inflammation, and microvascular obstruction are all hypothesized to be important in the aetio-pathogenesis of coma which characterizes cerebral malaria and the death which sometimes result. | 28413714 |
| Inflammation, Abscess | Altered Intercellular Communication | The Apparent Diffusion Coefficient (ADC) as a Potential Marker of Inflammation Associated with Body Abscesses. | 28413873 |
| Inflammation, Resectable Hepatocellular Carcinoma | Altered Intercellular Communication | The predictive value of integrated inflammation scores in the survival of patients with resected hepatocellular carcinoma: A Retrospective Cohort Study. | 28414120 |
| Inflammation, Liver carcinoma, Communicable Diseases, Hepatitis B, FAM126A gene | Altered Intercellular Communication | Evidence supports the predictive potential of inflammatory marker-derived scores (inflammation scores) and hepatitis B virus (HBV) infection on prognosis of patients with hepatocellular carcinoma (HCC). | 28414120 |
| Inflammation, FAM126A gene | Altered Intercellular Communication | Preoperative and dynamic changes in integrated inflammation scores, particularly for coCRP/ALB-PLR were important and stable prognostic markers in HCC. | 28414120 |
| Psoriasis, Inflammatory dermatosis, Dermatitis | Altered Intercellular Communication | Psoriasis is a common inflammatory skin disease and dendritic cells (DCs) play crucial role in the development of skin inflammation. | 28414181 |
| Obesity | Altered Intercellular Communication | A self-sustained loop of inflammation-driven inhibition of beige adipogenesis in obesity. | 28414311 |
| Inflammation, Obesity | Altered Intercellular Communication | In obesity, inflammation of white adipose tissue (AT) is associated with diminished generation of beige adipocytes ('beige adipogenesis'), a thermogenic and energy-dissipating function mediated by beige adipocytes that express the uncoupling protein UCP1. | 28414311 |
| Obesity | Altered Intercellular Communication | Our findings, established in both mouse systems and human systems, reveal a self-sustained cycle of inflammation-driven impairment of beige adipogenesis in obesity. | 28414311 |
| Fibrosis Assessment | Altered Intercellular Communication | Both bleomycin-induced inflammation and fibrosis were reduced in P2Y2R-deficient compared to wild type animals. | 28415591 |
| Inflammation, Fibrosis Assessment, Autoimmune Chronic Hepatitis | Altered Intercellular Communication | 31Phosphorus magnetic resonance spectroscopy of the liver for evaluating inflammation and fibrosis in autoimmune hepatitis. | 28415898 |
| Inflammation, Fibrosis Assessment, Autoimmune Chronic Hepatitis | Altered Intercellular Communication | Liver biopsy is the gold standard in evaluating inflammation and fibrosis in autoimmune hepatitis. | 28415898 |
| Inflammation | Altered Intercellular Communication | Phosphoenolpuryvate (PEP) correlated with the grade of inflammation (r = 0.746, p = .005) and thromboplastin time (r = 0.592, p = .043). | 28415898 |
| Inflammation | Altered Intercellular Communication | It also differentiated patients with active inflammation from patients without (t = 3.781, p = .009). | 28415898 |
| Inflammation, Fibrosis Assessment, Insemination, Artificial, Homologous | Altered Intercellular Communication | 31P MRS seems to detect active inflammation and advanced fibrosis in AIH patients. | 28415898 |
| Inflammation, Endothelial dysfunction | Altered Intercellular Communication | AAAs are associated with features of systemic inflammation and endothelial dysfunction. | 28416190 |
| Heart Diseases, atherosclerotic | Altered Intercellular Communication | There are confirmed beneficiary effects of exercise on atherosclerotic inflammation of ischemia-associated heart diseases. | 28417620 |
| Myocardial Ischemia, atherosclerotic | Altered Intercellular Communication | It seems that exercise may yield a better control of atherosclerotic inflammation in patients with ischemic heart disease through the induction of regulatory T cells. | 28417620 |
| Inflammation | Altered Intercellular Communication | The role of chronic inflammation in DKD is becoming widely accepted. | 28418911 |
| Osteitis, Choroidal and Ciliary Body Melanoma pT1d TNM Finding v8, Osteoporosis | Altered Intercellular Communication | Taken together, T1D combined with estrogen deficiency has a major effect on bone inflammation, which contributes to suppressed bone formation and osteoporosis. | 28419209 |
| Inflammation, Tuberculosis, Meningeal, HIV Infections | Altered Intercellular Communication | Leukotriene A4 Hydrolase Genotype and HIV Infection Influence Intracerebral Inflammation and Survival From Tuberculous Meningitis. | 28419368 |
| Inflammation, Fibrosis Assessment, Fatty degeneration, Liver Stiffness | Altered Intercellular Communication | Secondary outcomes included changes in steatosis, lobular inflammation, hepatocyte ballooning, NAS and fibrosis score, and anthropometric measurements, as well as glycemic, lipid, and liver profiles and liver stiffness measurements. | 28419855 |
| Inflammation, Infection, Cerebrovascular accident | Altered Intercellular Communication | Stroke-associated immunosuppression and inflammation are increasingly recognized as factors that trigger infections and thus, potentially influence the outcome after stroke. | 28419988 |
| Inflammation, Pain Distress Question | Altered Intercellular Communication | The present data show that subclinical inflammation is related to increased pain sensitivity, suggesting a potential role of inflammation in experimental pain which may be of importance for the development of clinical pain. | 28420008 |
| Pancreatic Trypsin Secretory Inhibitor, Kazal, Fibrosis Assessment, Inflammation | Altered Intercellular Communication | Transcriptome data revealed changes in genes linked with inflammation (CD68 and SAA), regeneration (SPINK1 and HGF), fibrosis (COL1A1), and stem cells (CD45). | 28420441 |
| Arterial Stiffness, Inflammation, Microvascular Angina, Atherosclerosis | Altered Intercellular Communication | The role of potential mechanistic pathways of arterial stiffness, atherosclerosis, microvascular disease, and inflammation were explored. | 28420646 |
| Inflammation, Sinus Thrombosis, Intracranial, Cerebral Infarction | Altered Intercellular Communication | However, she delivered a stillbirth, after which there was recurrence of acute cerebral infarction with LMCA occlusion, sinus thrombosis, and cranial base inflammation. | 28420846 |
| Meningitis | Altered Intercellular Communication | A thrice-weekly 100 mg dose of intrathecal isoniazid (INH) improved the signs of meningeal inflammation. | 28420846 |
| Inflammation, Psoriasis | Altered Intercellular Communication | CD93 is involved in angiogenesis and inflammation, both of which are key processes in the pathogenesis of psoriasis. | 28421233 |
| Inflammation, Obesity | Altered Intercellular Communication | Low-grade chronic inflammation in morbid obesity is associated with impaired iron metabolism. | 28421792 |
| Ischemia, Inflammation, Atrial Fibrillation by ECG Finding, Myopericarditis, osteoclast activating factor, Traumatic injury, physiopathological, Autonomic instability | Altered Intercellular Communication | From a pathophysiological point of view, a myriad of factors such as trauma, atrial dilation, ischemia, mechanical myopericarditis, autonomic imbalance, loss of connexins, AF nest remodeling, inflammation, sutures, and dysfunction caused by postextracorporeal circulation can contribute to postoperative atrial fibrillation (POAF) resulting in a longer hospital stay and consequently higher cost. | 28422282 |
| Inflammation, Anemia, Aspects of mortality statistics | Altered Intercellular Communication | Mortality is associated with inflammation, anemia, specific diseases and treatments, and molecular markers. | 28422991 |
| Inflammation, Prostate carcinoma | Altered Intercellular Communication | Low vitamin D status is associated with inflammation in patients with prostate cancer. | 28423553 |
| Inflammation, Prostate carcinoma | Altered Intercellular Communication | Inflammation may be an important mediator for prostate cancer progression in patients with low vitamin D status. | 28423553 |
| Inflammation, Primary malignant neoplasm | Altered Intercellular Communication | Altered expression of HMGB1 has been implicated in a wide range of pathological processes, including inflammation and cancer. | 28423715 |
| Diverticulum, Inflammation, Colon diverticulum anatomic structure, Sigmoid colon | Altered Intercellular Communication | Few studies have shown the associations between colonic diverticula and endoscopic findings such as location, inflammation, number of diverticula, sigmoid colon rigidity, and bowel habits. | 28425144 |
| Diverticulum, Inflammation, Sigmoid colon | Altered Intercellular Communication | Location and number of diverticula, inflammation, and sigmoid colon rigidity were evaluated from endoscopy results. | 28425144 |
| Inflammation, Multiple colonic diverticula, Colon diverticulum anatomic structure, Sigmoid colon, Constipation | Altered Intercellular Communication | In multivariate analysis, presence of constipation was associated with a significantly lower likelihood of left-sided colonic diverticula (odds ratio = 0.40, 95% confidence interval 0.20-0.82, P = 0.012), whereas right-sided and bilateral-sided colonic diverticula, multiple colonic diverticula, inflammation findings, and sigmoid colon rigidity were not related to bowel habits. | 28425144 |
| Inflammation, Colon diverticulum anatomic structure, Multiple diverticula, Sigmoid colon, Constipation | Altered Intercellular Communication | Among endoscopic findings related to colonic diverticula and bowel habits, only left-sided colonic diverticula were inversely associated with constipation, whereas inflammation findings, multiple diverticula, and sigmoid colon rigidity were not related to bowel habits. | 28425144 |
| Inflammation, Colon diverticulum anatomic structure | Altered Intercellular Communication | However, the association of inflammation findings with colonic diverticula and bowel habits should be further studied. | 28425144 |
| ARCN1 gene, Abnormal inflammatory response | Altered Intercellular Communication | SUV39H1 Reduction Is Implicated in Abnormal Inflammation in COPD. | 28425504 |
| Inflammation, Chronic Obstructive Airway Disease | Altered Intercellular Communication | Chronic obstructive pulmonary disease(COPD) is characterized by enhanced chronic inflammation in the airways, lung parenchyma, and circulation. | 28425504 |
| ARCN1 gene, Abnormal inflammatory response | Altered Intercellular Communication | We investigated whether SUV39H1, a histone methyltransferase, is causatively implicated in the abnormal inflammation observed in COPD. | 28425504 |
| ARCN1 gene, Inflammation | Altered Intercellular Communication | SUV39H1 knockdown reproduced the pattern of COPD inflammation, whereas SUV39H1 overexpression in COPD HSAEpCs rescued the H3K9me3 levels and suppressed inflammation. | 28425504 |
| ARCN1 gene, Inflammation | Altered Intercellular Communication | In COPD mice, chaetocin further repressed the SUV39H1/H3K9me3 levels and enhanced inflammation. | 28425504 |
| Exanthema, Inflammatory abnormality of the eye, Serositis, Myalgia, CTCAE 5 | Altered Intercellular Communication | Systemic symptoms can include rash, myalgia, ocular inflammation, and serositis. | 28427379 |
| Hereditary Autoinflammatory Diseases | Altered Intercellular Communication | Given her protracted clinical course and maternal history of a poorly defined inflammatory condition, an autoinflammatory disease was considered. | 28427379 |
| Inflammation | Altered Intercellular Communication | Increasing evidence has indicated that insulin resistance is associated with inflammation. | 28428029 |
| Infiltration, Necrosis with inflammation | Altered Intercellular Communication | The prominent features were lobular necrosis/inflammation (97.7%), plasma cell infiltration (96.4%), emperipolesis (89.3%), pigmented macrophages (84.5%), cobblestone appearance of hepatocytes (82.6%) and perivenular necroinflammatory activity, including centrilobular necrosis (81.4%). | 28428284 |
| Inflammation, Malnutrition, Chronic Kidney Diseases, Atherosclerosis | Altered Intercellular Communication | Both inflammation and malnutrition have been reported to be closely linked to atherosclerosis, especially in patients with chronic kidney disease (CKD). | 28428450 |
| SNCG gene, Inflammation, Lewy Bodies | Altered Intercellular Communication | This microbiological pattern of gut microflora can trigger local inflammation followed by aggregation of a-synuclein and generation of Lewy bodies. | 28429209 |
| Inflammation, atherosclerotic | Altered Intercellular Communication | Associations of Osteocalcin, Osteoprotegerin, and Calcitonin with Inflammation Biomarkers in Atherosclerotic Plaques of Coronary Arteries. | 28429221 |
| Inflammation, Obesity | Altered Intercellular Communication | Obesity is associated with a state of chronic low-grade inflammation. | 28429893 |
| Inflammation | Altered Intercellular Communication | This may occur because of depressing inflammation and improving circulating EPCs. | 28430117 |
| Inflammation, Cachexia, Cardiovascular system | Altered Intercellular Communication | The Association of Ankle Brachial Index, Protein-Energy Wasting, and Inflammation Status with Cardiovascular Mortality in Patients on Chronic Hemodialysis. | 28430145 |
| HD Term Type, Inflammation | Altered Intercellular Communication | We investigated the association of abnormal ankle brachial index (ABI), PEW, and chronic inflammation status with clinical prognosis in HD patients. | 28430145 |
| prostatitis | Altered Intercellular Communication | Prostate-specific antigen increase during dutasteride to indicate the need for prostate biopsy: influence of prostatic inflammation. | 28430341 |
| prostatitis | Altered Intercellular Communication | We focused our attention on the rate of the first PSA increase and on the influence of prostatic inflammation. | 28430341 |
| Inflammation, Liver carcinoma | Altered Intercellular Communication | Systemic inflammation response index (SIRI) predicts prognosis in hepatocellular carcinoma patients. | 28430597 |
| Inflammation, Primary malignant neoplasm | Altered Intercellular Communication | The systemic inflammation response index (SIRI) is a useful tool for predicting prognosis in some types of cancer. | 28430597 |
| Communicable Diseases, Inflammation | Altered Intercellular Communication | However, distinguishing between inflammation and infection is a challenge. | 28430741 |
| Inflammation, Disease remission | Altered Intercellular Communication | At d2, half of the patients (6/12) showed active disease, whereas ileo-colonoscopy revealed significant inflammation in 5/15 (33%). | 28431493 |
| Inflammation, ovarian neoplasm | Altered Intercellular Communication | Inflammation plays an important role in the pathogenesis of ovarian cancer. | 28431566 |
| ovarian neoplasm | Altered Intercellular Communication | The CRP/Alb is a novel independent marker of poor prognosis among ovarian cancer patients and shows superior prognostic ability compared to the established inflammation-based prognostic indices. | 28431566 |
| Inflammation, Psoriasis | Altered Intercellular Communication | Serum peptides as putative modulators of inflammation in psoriasis. | 28431948 |
| Inflammation | Altered Intercellular Communication | Interleukin-6 (IL-6) is a driver of inflammation and associated endothelial cell activation in acute coronary syndromes. | 28432157 |
| Inflammation, Hyperparathyroidism, Primary | Altered Intercellular Communication | Low-grade inflammation and tryptophan-kynurenine pathway activation are associated with adverse cardiac remodeling in primary hyperparathyroidism: the EPATH trial. | 28432842 |
| Inflammation, Hyperparathyroidism, Primary, Electrocardiogram: left ventricle hypertrophy (finding) | Altered Intercellular Communication | Primary hyperparathyroidism (pHPT) is associated with low-grade inflammation, left ventricular hypertrophy and increased cardiovascular mortality, but the association between inflammatory markers and parameters of adverse cardiac remodeling is unknown. | 28432842 |
| Inflammation | Altered Intercellular Communication | Conclusions: Cardiac remodeling is common in pHPT and is associated with low-grade inflammation and activation of the tryptophan-kynurenine pathway. | 28432842 |
| Degenerative polyarthritis, Inflammation, Pain Distress Question | Altered Intercellular Communication | The role of inflammation and pain in osteoarthritis (OA) is not fully understood. | 28433814 |
| Inflammation, Fibrosis Assessment | Altered Intercellular Communication | It has been characterized as either inflammation of the median nerve caused by compression or noninflammatory fibrosis of the subsynovial connective tissue (SSCT). | 28433831 |
| Inflammation, Hyperreactivity, Data types - Address | Altered Intercellular Communication | We show hyperreactivity of Ab plaque-associated microglia upon systemic inflammation in transgenic AD mouse models (i.e., 5XFAD and APP23). | 28434692 |
| Inflammation, Traumatic injury | Altered Intercellular Communication | High mastery may protect against elevated systemic inflammation associated with substantial lifetime trauma exposure. | 28437379 |
| Inflammation | Altered Intercellular Communication | Individuals who experience declines in mastery may be most susceptible to increases in inflammation associated with chronic stress. | 28437379 |
| Airway structure, ARCN1 gene | Altered Intercellular Communication | Post-bronchodilator Reversibility of FEV1 and Eosinophilic Airway Inflammation in COPD. | 28438346 |
| Airway structure, ARCN1 gene | Altered Intercellular Communication | The relationship between bronchodilator responsiveness and eosinophilic airway inflammation has not been well documented in COPD. | 28438346 |
| Inflammation, Organ Dysfunction Scores | Altered Intercellular Communication | To investigate whether systemic inflammation in acutely admitted older medical patients (age >65 years) is associated with physical performance and organ dysfunction. | 28438470 |
| Inflammation, Organ Dysfunction Scores | Altered Intercellular Communication | Organ dysfunction's association with physical performance, and whether these associations are mediated by systemic inflammation, was also investigated. | 28438470 |
| Inflammation | Altered Intercellular Communication | FI-OutRef was also associated with physical performance (all p<0.001); suPAR being the inflammatory biomarker with the highest impact when adjusting for inflammation. | 28438470 |
| Intraocular inflammation | Altered Intercellular Communication | This case highlights IgG4-RD as a rare cause of intraocular inflammation that may progress to involve the orbit. | 28438752 |
| IgG4-Related Sclerosing Disease | Altered Intercellular Communication | IgG4-related disease (IgG4-RD) is a rare, chronic inflammatory condition that may involve nearly every organ system. | 28438752 |
| Increased insulin level, Inflammation, Obesity | Altered Intercellular Communication | We conclude that a decrease in mitochondrial BCAA degradation and an increase in inflammation in SAT co-occur and associate with hyperinsulinemia and large adipocyte size in unhealthy obesity. | 28439093 |
| Inflammation | Altered Intercellular Communication | Factors contributing to elevated inflammation in racial/ethnic minority populations are not well understood. | 28439184 |
| Inflammation, Metabolic Diseases | Altered Intercellular Communication | Abdominal fat accumulation after menopause is associated with low-grade inflammation and increased risk of metabolic disorders. | 28440046 |
| Airway structure, Asthma | Altered Intercellular Communication | Instead, sST2 predicts a subphenotype of asthma characterized by increased levels of FeNO, a marker for eosinophilic airway inflammation. | 28440062 |
| Airway structure, Asthma, Wheezing | Altered Intercellular Communication | Our study indicates that sST2 in preschool wheezers has predictive value for the development of eosinophilic airway inflammation in asthmatic children at school age. | 28440062 |
| Inflammation, Cardiac function | Altered Intercellular Communication | A total of 3 weeks following injection, this resulted in severe inflammation and significant deterioration of cardiac function. | 28440472 |
| Inflammation | Altered Intercellular Communication | After population-based baseline screening, 145 precursor and 335 chronic inflammation cases were endoscopically surveyed for six years. | 28440945 |
| RANGAP1 wt Allele, Inflammation, Dysplasia | Altered Intercellular Communication | Surveillance of interval and baseline diagnoses for 18 severe dysplasia (SD) cases later detected were: 13, 23, 39, and 44 months since a diagnosis of chronic inflammation in four cases; 6, 6, 6, 11, 13, 16, 16, and 23 months since mild dysplasia (mD) diagnoses in eight; and 6, 9, 10, 13, 18, and 48 months since moderate dysplasia (MD) diagnoses in six. | 28440945 |
| Exophthalmos, Conjunctivitis, Corneal Ulcer | Altered Intercellular Communication | We examined a conjunctival biopsy from a 69-year-old woman who developed unilateral conjunctival inflammation together with a neurotrophic corneal ulcer and proptosis. | 28441073 |
| Dryness (characteristic), Inflammatory abnormality of the eye, Nerve injury | Altered Intercellular Communication | The functional role of Langerhans cells (LCs) in ocular surface inflammation and nerve damage in dry eye (DE) disease has yet to be determined. | 28441413 |
| Inflammatory abnormality of the eye, Disease | Altered Intercellular Communication | These data support a functional role for LCs in negatively regulating ocular surface inflammation and exhibiting a neuroprotective function in DE disease. | 28441413 |
| Inflammation | Altered Intercellular Communication | The extent to which the gastrointestinal microbiome and peripheral inflammation are associated with ME/CFS remains unclear. | 28441964 |
| Inflammation, Anemia | Altered Intercellular Communication | Appropriate investigations for iron status and inflammation/infection screening, need to be integral in the evaluation of anaemia and its causes before anaemia control interventions are implemented. | 28441968 |
| Granuloma | Altered Intercellular Communication | Histopathology shows interstitial granulomas composed of epitheloid histiocytes in the reticular dermis with surrounding foci of collagen degeneration and variable neutrophilic inflammation. | 28442268 |
| Inflammation, Stomach Carcinoma | Altered Intercellular Communication | Interleukin-6 (IL-6) and its receptor (IL-6R) were regarded to be responsible for the occurrence of gastric cancer for their regulation roles in the inflammation. | 28442395 |
| Inflammation, Platelet destruction | Altered Intercellular Communication | A shared immunologic pathway leading to mucosal inflammation and platelet destruction has been proposed. | 28442528 |
| Inflammation, Cardiovascular Diseases | Altered Intercellular Communication | The correlation between 25(OH)D levels, inflammation markers, BMI, and FLI showed an increased risk of cardiovascular disease in this cohort of workers. | 28443804 |
| Janus kinase, Inflammation | Altered Intercellular Communication | Janus kinase (JAK) and spleen tyrosine kinase (SYK) play critical functions in T-cell activation and in inflammation. | 28445193 |
| Intraocular inflammation, Failure (biologic function), Uveitis | Altered Intercellular Communication | The primary end point was the time to treatment failure, defined according to a multicomponent intraocular inflammation score that was based on the Standardization of Uveitis Nomenclature criteria. | 28445659 |
| Pulmonary arterial hypertension, Inflammation, Polycyclic Hydrocarbons, Aromatic | Altered Intercellular Communication | Chronic inflammation emerges as a feature of the pathogenesis of pulmonary arterial hypertension (PAH) in experimental models. | 28446163 |
| Inflammation, Traumatic injury | Altered Intercellular Communication | Oxylipins are potent lipid mediators demonstrated to initiate and regulate inflammation yet little is known regarding their involvement in the response to surgical trauma. | 28446191 |
| Degenerative polyarthritis, Inflammation | Altered Intercellular Communication | Recent data suggest its association with low-grade inflammation in osteoarthritis (OA). | 28446208 |
| Refractory anemias, Inflammation | Altered Intercellular Communication | Our data provide the first evidence of S100A11 up-regulation and its association with inflammation and disease activity in patients with RA. | 28446208 |
| Sepsis, Inflammation | Altered Intercellular Communication | Mesenchymal stem cells (MSCs) have been shown to reduce sepsis-induced inflammation and improve survival in mouse models of sepsis. | 28446249 |
| Sepsis | Altered Intercellular Communication | CD16+ monocytes are proinflammatory and abundant in inflammatory conditions such as sepsis. | 28446249 |
| Hypertension, CTCAE | Altered Intercellular Communication | A pro-inflammatory diet is thought to lead to hypertension through oxidative stress and vessel wall inflammation. | 28446366 |
| Inflammation, Fibrosis Assessment | Altered Intercellular Communication | Skin histopathologic examination demonstrated the presence of mucin deposits, dermal fibrosis, fibrocytes and perivascular inflammation. | 28446858 |
| Inflammation, Obesity | Altered Intercellular Communication | The association between inflammation, obesity and elevated blood pressure in 16-25-year-old females. | 28447628 |
| Inflammation, Obesity | Altered Intercellular Communication | There is evidence to show an association between inflammation, obesity and elevated blood pressure. | 28447628 |
| Inflammation | Altered Intercellular Communication | Chronic inflammation is linked to many chronic conditions. | 28448077 |
| Inflammation | Altered Intercellular Communication | One of the strongest modulators of chronic inflammation is diet. | 28448077 |
| Inflammation, Obesity | Altered Intercellular Communication | Various inflammation parameters are increased with childhood obesity, but few comparable data are found in lean growing athletes. | 28448210 |
| Sarcoidosis, Myocarditis | Altered Intercellular Communication | Conclusion Quantitative myocardial tissue characterization with T1 and T2 mapping may enable noninvasive recognition of cardiac involvement and activity of myocardial inflammation in patients with systemic sarcoidosis. | 28448233 |
| Inflammation, "Alzheimers Disease", Data types - Address | Altered Intercellular Communication | There is increasing evidence for the involvement of chronic inflammation and oxidative stress in the pathogenesis of Alzheimer's disease (AD). | 28448946 |
| Ulcerative Colitis | Altered Intercellular Communication | The endoscopic features of IBD-TA at initial diagnosis (n = 8) showed discontinuous and focal mucosal inflammations (n = 7, 87.5%), and only one case was diagnosed as ulcerative colitis (UC) at the first colonoscopy. | 28449344 |
| Inflammation | Altered Intercellular Communication | TCM is characterized by changes in cardiomyocyte and mitochondrial morphology accompanied by a macrophage-dominated cardiac inflammation. | 28449778 |
| Inflammation, Mitral restenosis | Altered Intercellular Communication | Late mitral restenosis after percutaneous commissurotomy: Predictive value of inflammation and extracellular matrix remodeling biomarkers. | 28450150 |
| Inflammation, Mitral restenosis | Altered Intercellular Communication | The role of chronic inflammation in mitral restenosis after percutaneous mitral commissurotomy (PMC) is still controversial. | 28450150 |
| Inflammation, Mitral restenosis | Altered Intercellular Communication | We sought to assess the predictive value of inflammation and extracellular matrix (ECM) remodeling biomarkers in late mitral restenosis after PMC. | 28450150 |
| Inflammation, Mitral restenosis | Altered Intercellular Communication | Chronic inflammation and ECM remodeling are involved in late mitral restenosis after PMC. | 28450150 |
| Alzheimers Disease", Data types - Address, Cell body of neuron | Altered Intercellular Communication | Alzheimer's disease (AD), a debilitating neurodegenerative illness, is characterized by neuronal cell loss, mental deficits, and abnormalities in several neurotransmitter and protein systems. | 28450267 |
| Inflammation, Liver Failure, Acute | Altered Intercellular Communication | MerTK expressing hepatic macrophages promote the resolution of inflammation in acute liver failure. | 28450389 |
| Hepatitis, Necrosis, GTF2A1L wt Allele, Cessation of life, Liver Failure, Acute | Altered Intercellular Communication | Acute liver failure (ALF) is characterised by overwhelming hepatocyte death and liver inflammation with massive infiltration of myeloid cells in necrotic areas. | 28450389 |
| Acute inflammation | Altered Intercellular Communication | The mechanisms underlying resolution of acute hepatic inflammation are largely unknown. | 28450389 |
| Inflammation, GTF2A1L wt Allele, Injury of liver | Altered Intercellular Communication | Compared with WT mice which show an increase of MerTK+MHCIIhigh macrophages during the resolution phase in ALF, APAP-treated Mer-/- mice exhibit persistent liver injury and inflammation, characterised by a decreased proportion of resident Kupffer cells and increased number of neutrophils. | 28450389 |
| Cluster, Observation Method - Coagulation, Inflammation | Altered Intercellular Communication | Cluster analysis of 20 biomarkers of inflammation, coagulation and endothelial activation provided the phenotypes in a training cohort, not taking any outcome data into account. | 28450529 |
| Inflammation, Comorbidity | Altered Intercellular Communication | However, switching to open surgery as well as increase of complications in patients who admitted with severe inflammation attack and who have high comorbidity, caution should be exercised when selecting patients for early operation. | 28451027 |
| hyperthermia treatment, Leukocytosis, Acute inflammation | Altered Intercellular Communication | We evaluated postoperative inflammation based on duration of hyperthermia (body temperature >=38 degC) and leukocytosis (>=12,000/uL-1). | 28451762 |
| Inflammation, Leukocytosis, hyperthermia treatment | Altered Intercellular Communication | The prolonged inflammation group comprised 57 (11.7%) patients who had hyperthermia for 4 days or longer and 42 (8.6%) patients who had leukocytosis for 7 days or longer. | 28451762 |
| Inflammation, Brain Injury, Chronic | Altered Intercellular Communication | We found that in MDA5+ DMIP, acute alveolar inflammation caused a poor prognosis early in the disease course, and in ARS+ DMIP, chronic injury to the alveolar epithelial cells or basement membrane caused long-term recurrence. | 28451794 |
| Airway structure, Coughing | Altered Intercellular Communication | Upper airway inflammation is one of the most commonly identified causes of chronic cough, although the underlying mechanism is not clear. | 28452705 |
| Gastrointestinal inflammation, Ulcerative Colitis | Altered Intercellular Communication | Pathogenic or protective functions of these cells during human intestinal inflammation, such as ulcerative colitis [UC], have not previously been defined, with understanding largely derived from animal model data. | 28453768 |
| Retinitis | Altered Intercellular Communication | Aberrant activation of the Wnt/b-catenin signaling pathway plays a pathogenic role in retinal inflammation and neovascularization. | 28455497 |
| Inflammation, Fibrosis Assessment, Pericarditis, CTCAE, Calcinosis | Altered Intercellular Communication | Idiopathic and postsurgical constrictive pericarditis is characterized by pericardial structural remodeling that involves fibrosis, calcification, and inflammation. | 28456362 |
| Inflammatory, Inflammation, Intestines, Crohn Disease | Altered Intercellular Communication | The sensitivity for detection of intestinal bowel thickening (a surrogate of inflammation) was 90%, and for detection of Crohn's disease complications, namely bowel stenosis and inflammatory mass, was 94% and 75%, respectively. | 28457088 |
| Inflammatory Bowel Diseases, Inflammation | Altered Intercellular Communication | Bowel ultrasound is a useful and feasible bedside imaging tool for the detection of inflammation and complications in IBD patients. | 28457088 |
| Inflammation, Pathology | Altered Intercellular Communication | This process increases the magnitude of inflammation and may influence the development of gastric pathologies. | 28458166 |
| Inflammation, Fibrosis Assessment, Stenosis, Pancreatitis | Altered Intercellular Communication | The underlying etiology of this case may have been the formation of a cicatricial stricture during the resolution of WON, in addition to fibrosis caused by the spreading of inflammation from pancreatitis. | 28458308 |
| vascular inflammations | Altered Intercellular Communication | Interleukin-10 (IL-10) plays a vital part in the pathophysiology of vascular inflammation. | 28459600 |
| Bethesda units, Inflammation, Inflammatory disorder, Uveitis | Altered Intercellular Communication | Birdshot Uveitis (BU) is an archetypical chronic inflammatory eye disease, with poor visual prognosis, that provides an excellent model for studying chronic inflammation. | 28459868 |
| Inflammation, Primary malignant neoplasm, Rheumatoid Arthritis, Cardiovascular Diseases | Altered Intercellular Communication | Human Leukocyte Antigen Shared Epitope and Inflammation, Cardiovascular Disease, Cancer, and Mortality Among Postmenopausal Women in the Women's Health Initiative Rheumatoid Arthritis Study. | 28459968 |
| Refractory anemias, Inflammation, Tenosynovitis | Altered Intercellular Communication | MRI-detected tenosynovitis was associated with RA development independent of other types of MRI-detected inflammation [odds ratio (OR) = 7.5, 95% CI: 2.4, 23] and also independent of age and other inflammatory measures (swollen joints, CRP) (OR = 4.2, 95% CI: 1.4, 12.9). | 28460018 |
| Lung Diseases, Obstructive, Syndrome | Altered Intercellular Communication | Radiographic Evidence of Sinonasal Inflammation in Asthma-Chronic Obstructive Pulmonary Disease Overlap Syndrome: An Underrecognized Association. | 28460847 |
| ARCN1 gene, Inflammation, Asthma, Chronic Obstructive Airway Disease | Altered Intercellular Communication | Sinonasal inflammation on both clinical examinations and imaging significantly impacts both asthma and chronic obstructive pulmonary disease (COPD). | 28460847 |
| Inflammation, Asthma-Chronic Obstructive Pulmonary Disease Overlap Syndrome | Altered Intercellular Communication | The objective of this study was to examine the association between sinonasal inflammation and asthma-COPD overlap syndrome (ACOS). | 28460847 |
| ARCN1 gene, Inflammation, Asthma | Altered Intercellular Communication | The frequency of radiographic evidence of sinonasal inflammation in patients with COPD, asthma, ACOS was 60.0%, 94.9%, and 72.2%, respectively. | 28460847 |
| ARCN1 gene, Inflammation, Asthma, levamisole | Altered Intercellular Communication | Patients with ACOS and COPD had only mild radiographic evidence of sinonasal inflammation (LMS score, 1-7), whereas moderate (LMS score, 8-11) and severe (LMS score, >=12) radiographic evidence of sinonasal inflammation were detected only in patients with asthma. | 28460847 |
| Inflammation, Comorbidity | Altered Intercellular Communication | Radiographic evidence of sinonasal inflammation was a common comorbidity in ACOS. | 28460847 |
| Exanthema, Inappropriate ADH Syndrome, Communicable Diseases, Encephalitis, herpesvirus 3, human, Acute cerebellar ataxia | Altered Intercellular Communication | We report a case of varicella-zoster virus (VZV) infection with acute cerebellitis and encephalitis with associated Syndrome of Inappropriate Antidiuretic Hormone Secretion (SIADH) in an elderly man presenting with acute cerebellar ataxia without antecedent rash. | 28460866 |
| Giant Cell Arteritis, Inflammation, GCA gene, Cutaneous Small Vessel Vasculitis | Altered Intercellular Communication | We investigated the diagnostic value of inflammation limited to the adventitia (ILA), and isolated vasa vasorum or small-vessel vasculitis (VVV, SVV) in temporal artery biopsies (TAB) for giant cell arteritis (GCA). | 28461644 |
| Inflammation, Dyslipidemias, Dental Plaque, Diabetes Mellitus, Non-Insulin-Dependent | Altered Intercellular Communication | Ameliorating dyslipidemia in type 2 diabetic patients by femoropopliteal artery plaque resection under acute inflammation response. | 28462578 |
| Inflammation, "Alzheimers Disease", Cognition Disorders, Data types - Address | Altered Intercellular Communication | The role of inflammation in Alzheimer's disease (AD) and other cognitive disorders is unclear. | 28464009 |
| Inflammation, Fibrosis Assessment | Altered Intercellular Communication | LBP was correlated with lobular inflammation (P=.001), while both LBP (P=.0004) and endotoxin levels (P=0.008) were correlated with fibrosis. | 28464257 |
| Inflammation | Altered Intercellular Communication | Epicardial fat causes inflammation and contributes to progression of CAD. | 28464274 |
| Meningitis | Altered Intercellular Communication | Spread/fill foci are associated with reduced cortical gray matter volumes and may represent blood-meningeal barrier breakdown near sites of meningeal inflammation, whereas nodular foci may be a normal variant. | 28464368 |
| Cerebrovascular, Inflammation, Psoriasis, Inflammatory disorder | Altered Intercellular Communication | Psoriasis is a multifactorial inflammatory disorder, in which the inflammation affects not only the skin but also the other internal organs, and can induce cardiovascular and cerebrovascular involvements. | 28464401 |
| Chronic frontal sinusitis, polyps, Sinusitis, Inflammation | Altered Intercellular Communication | Eosinophilic chronic frontal sinusitis is difficult to treat compared with non-eosinophilic sinusitis because of recurring inflammation and polyp formation in the frontal recess after the post-operative follow-up period. | 28464955 |
| Inflammation | Altered Intercellular Communication | Concomitantly, clinical parameters and serum markers of inflammation were found reduced. | 28465139 |
| Inflammation, Data types - Address | Altered Intercellular Communication | CD68 may play key roles in the pathogenesis of AD and its complications may be via induction of inflammation. | 28465247 |
| Inflammation | Altered Intercellular Communication | In the early postoperative period, the protein expression of inflammatory cytokines implicates that fibrin glue may induce accelerated healing and subdued inflammation on the ocular surface compared to sutures. | 28465659 |
| Neurodegenerative Disorders, Primary malignant neoplasm, Inflammation | Altered Intercellular Communication | Oxidative stress, a disturbance in the balance between oxidant/antioxidant ratios, is associated with cancer, aging, inflammation, neurodegenerative diseases and other conditions. | 28466919 |
| Inflammation | Altered Intercellular Communication | The SOFA, GOS, and inflammation factors were significantly better in the zinc-supplemented group by day 16 (all p < .05). | 28467150 |
| Osteogenesis, Inflammation, OSSIFICATION OF THE POSTERIOR LONGITUDINAL LIGAMENT OF SPINE | Altered Intercellular Communication | Serum biomarkers in patients with ossification of the posterior longitudinal ligament (OPLL): Inflammation in OPLL. | 28467440 |
| Inflammation, OSSIFICATION OF THE POSTERIOR LONGITUDINAL LIGAMENT OF SPINE | Altered Intercellular Communication | The results may suggest the occurrence of local inflammation in OPLL and the inflammation might cause OPLL progression. | 28467440 |
| Malignant tumor of colon, Inflammation | Altered Intercellular Communication | The occurrence and development of colon cancer is closely related to inflammation. | 28467774 |
| Inflammation, Fibrosis Assessment, Granulomatous inflammation | Altered Intercellular Communication | Soft tissue reactions to paraffin include inflammation, fibrosis, disfigurement, and granulomatous inflammation with foreign body giant cell reaction. | 28468169 |
| Necrotizing granulomatous inflammation, Bacterial Infections, Actinomycosis | Altered Intercellular Communication | Actinomycosis, an infectious bacterial disease caused by Actinomyces species, is very rare and is characterized by contiguous spreading, subacute to chronic granulomatous inflammation and the formation of multiple abscesses and sinus tracts that may discharge sulfur granules. | 28468217 |
| Aneurysm, Inflammation | Altered Intercellular Communication | Histology revealed evidence for a true aneurysm without overt, acute, or chronic inflammation of the surrounding gastric mucosa. | 28468689 |
| Cerebral Small Vessel Diseases, Inflammation, Hypertension, CTCAE | Altered Intercellular Communication | In the brain, enlarged perivascular spaces (PVS) relate to cerebral small vessel disease (SVD), poor cognition, inflammation and hypertension. | 28468952 |
| Mammary Neoplasms | Altered Intercellular Communication | To address this paradox, we evaluated relation between IL17A and IL32 expression and other inflammation- and T cell response-associated genes in breast tumors. | 28470472 |
| Inflammation, Juvenile-Onset Still Disease | Altered Intercellular Communication | Adult-onset Still's disease (AOSD) is characterized by multiple systemic inflammation of unknown etiology. | 28470759 |
| Degenerative polyarthritis, Inflammation, Rheumatoid Arthritis | Altered Intercellular Communication | Ultrasonography-detected subclinical inflammation in patients with hand osteoarthritis and established rheumatoid arthritis: a comparison between two different pathologies using the same ultrasound examination protocol. | 28471034 |
| Degenerative polyarthritis, Joint swelling, Synovial Hypertrophy, Refractory anemias | Altered Intercellular Communication | Subclinical joint inflammation in the context of equivocal clinical examination was found in 9.6% of OA patients compared with 46.4% of RA patients (p = 0.0001), despite the fact that there was no significant difference between the degree of chronic joint swelling (synovial hypertrophy grades 2 and 3; p = 0.75 and p = 0.11, respectively). | 28471034 |
| Refractory anemias, Inflammation, Degenerative polyarthritis | Altered Intercellular Communication | Our study findings reflected differences between the incidence and characteristics of subclinical inflammation in patients with RA and OA, which could be helpful in patients with an equivocal clinical examination or history of both diseases. | 28471034 |
| Degenerative polyarthritis, Inflammation, Synovitis, Refractory anemias | Altered Intercellular Communication | Almost one in 10 patients with hand OA had active synovitis, while almost one in two patients with RA had uncontrolled inflammation in at least one joint. | 28471034 |
| Inflammation, Vascular Diseases | Altered Intercellular Communication | Galectin-3 is a modulator of oxidative stress, inflammation, and fibrogenesis involved in the pathogenesis of vascular diseases. | 28471381 |
| Lupus Erythematosus, Systemic | Altered Intercellular Communication | This has led to the proposal of a hormonal role in the development of SLE. | 28471600 |
| Inflammation, Brain hemorrhage | Altered Intercellular Communication | Postmortem pathologic analysis revealed aspergillus-associated inflammation of blood vessels and ischemic and petechial hemorrhagic strokes in the affected territories. | 28471899 |
| Communicable Diseases, Inflammation, Infection | Altered Intercellular Communication | Infections represented 82.6% of all cases with a leukocyte count >100 x 10/L whereas 56.3% of cases with at leukocyte counts <100 x 10/L were dominated by disease not related to infection.The present study may serve as a reminder to clinicians of what diseases and disease categories to suspect when patients present with CSF biochemistry indicating CNS inflammation. | 28471963 |
| Infection | Altered Intercellular Communication | Infections were the most common cause of CSF pleocytosis (61.4%) followed by miscellaneous causes (12.7%), vascular (9.7%), neurodegenerative (7%), neoplastic (5%), and inflammatory conditions (4.2%). | 28471963 |
| Chronicity, Inflammation, Inflammatory Bowel Diseases, Pulmonary Dysfunction | Altered Intercellular Communication | The chronicity of inflammation might probably reduce the possibility of developing pulmonary dysfunction, while the erythrocyte sedimentation rate (ESR) was found as a harmful factor for developing pulmonary dysfunction.The pulmonary function significantly decreases in IBD patients and is characterized by either simple restrictive/obstructive dysfunction or mixed. | 28471982 |
| Inflammation, Aggressive behavior, Macrophage Chemotactic Factors | Altered Intercellular Communication | Additionally, prolonged exposure of MCF cells to IL6 or IL8 induced the appearance of senescent cells, suggesting a mechanism by which senescence and inflammation are reinforced favouring the acquisition of EMT and stem-like features at the population level, thus increasing tumour aggressiveness. | 28472950 |
| Intraocular inflammation | Altered Intercellular Communication | The macular hole was managed with macular hole surgery after intraocular inflammation had resolved. | 28473358 |
| Inflammation, Atherosclerosis | Altered Intercellular Communication | Human Plasma Thioredoxin-80 Increases With Age and in ApoE-/- Mice Induces Inflammation, Angiogenesis, and Atherosclerosis. | 28473446 |
| Inflammation, Congenital Abnormality | Altered Intercellular Communication | The correlations observed indicate that lipids abnormalities, inflammation, and oxidative stress may be involved in this destructive process. | 28473982 |
| Inflammation, Perivascular inflammation | Altered Intercellular Communication | Vascular and/or perivascular involvements of sclerotic inflammation (perivasculitis) are a complication of immunoglobulin G4-related disease (IgG4-RD). | 28474137 |
| Airway structure, Asthma | Altered Intercellular Communication | Here, we evaluated the frequencies and activation status of basophils in the sputum of adult asthmatic patients and related our findings to other parameters of eosinophilic airway inflammation. | 28474352 |
| Airway structure, Asthma | Altered Intercellular Communication | A trial of oral corticosteroids for persistent systemic and airway inflammation in severe asthma. | 28474411 |
| Inflammation, Asthma | Altered Intercellular Communication | The fraction of exhaled nitric oxide (FeNO) and blood eosinophils, markers of local and systemic eosinophilic inflammation, respectively, are increased in asthmatic patients. | 28474411 |
| Inflammation, Endothelial dysfunction | Altered Intercellular Communication | Activation of renin-angiotensin-aldosterone and endothelin systems plays a key role in endothelial dysfunction, vascular remodelling, and aging by inducing reactive oxygen species production, and promoting inflammation and cell growth. | 28474545 |
| Inflammation, Nasal Polyps, Chronic sinusitis, Craniosynostosis | Altered Intercellular Communication | Chronic rhinosinusitis (CRS) with nasal polyps (CRSwNP) is characterized by type 2 inflammation with high levels of Th2 cytokines. | 28474861 |
| Inflammation | Altered Intercellular Communication | These results suggest that ILC2 are not only elevated but also activated in CRSwNP in vivo and that ILC2 may play important roles in the type 2 inflammation in CRSwNP. | 28474861 |
| Inflammation, Hyperpigmentation | Altered Intercellular Communication | Clinically, 3 main distinct types of hyperpigmentation by minocycline have been distinguished: type I, with blue-gray to black pigment on the face in areas of scarring or inflammation; type II, with blue-gray pigment on normal skin of the legs, forearms and on the shins; and type III, with a diffuse muddy-brown discoloration in areas of sun exposure. | 28475520 |
| Inflammation, Fibrosis Assessment, Chronic infectious disease | Altered Intercellular Communication | We evaluated the diagnostic usefulness of these markers in hepatic fibrosis and inflammation of patients with chronic viral infection. | 28475652 |
| Inflammation, Traumatic injury | Altered Intercellular Communication | Experimental studies suggest that mechanical cell washing to remove pro-inflammatory components that accumulate in the supernatant of stored donor red blood cells (RBCs) might reduce inflammation and organ injury in transfused patients. | 28475670 |
| Inflammation, Obesity, Visceral, Metabolic Syndrome X, Hyperglycemia, Malignant neoplasm of gastrointestinal tract | Altered Intercellular Communication | Visceral obesity and metabolic syndrome (MetSyn) represent a constellation of inflammation, insulin resistance, and hyperglycemia and are established risk factors for gastrointestinal cancer. | 28475745 |
| Inflammation | Altered Intercellular Communication | Systematic review of the literature illustrated high consistency in the association between these biomarkers of inflammation and renal outcomes in DKD. | 28476763 |
| Fibrosis Assessment, Liver damage, Hepatitis | Altered Intercellular Communication | The marker seems to reflect not only liver fibrosis but also other factors, such as liver inflammation, liver damage, and hepatocyte regeneration. | 28477171 |
| Inflammation, Data types - Address | Altered Intercellular Communication | Inflammation is frequently related to AD, whereas microglial cells are the major phagocytes in the brain and mediate the removal of Ab peptides. | 28477215 |
| Inflammation, Schizophrenia | Altered Intercellular Communication | A molecular pathway analysis stresses the role of inflammation and oxidative stress towards cognition in schizophrenia. | 28477285 |
| Inflammation | Altered Intercellular Communication | We report that inflammation and in particular the pathway associated with arachidonic acid was enriched in mutations associated with poorer performance at the verbal memory and working memory tasks in SKZ patients. | 28477285 |
| Inflammation, Vascular Diseases, Erysipelas, Lichen Sclerosus et Atrophicus, Alcohol abuse | Altered Intercellular Communication | The diagnosis of ACA is often clinically missed for months or years, and may be mistaken at the inflammation phase for vascular disorders, erysipelas or bursitis/arthritis, and at the atrophic phase for lichen sclerosus atrophicus, morphoea or anetoderma. | 28477365 |
| Inflammation | Altered Intercellular Communication | Nutritional support and resistance training were shown to increase muscle anabolism and reduce inflammation in healthy elderly. | 28477944 |
| Inflammation, Systemic Inflammatory Response Syndrome | Altered Intercellular Communication | We hypothesized that nutritional support and resistance training would accelerate the resolution of inflammation in hospitalized elderly patients with SIRS. | 28477944 |
| Inflammation, "Marjolins ulcer | Altered Intercellular Communication | A known risk factor for cSCC is chronic inflammation; a cSCC that develops at a site of chronic inflammation is known as Marjolin's ulcer. | 28478388 |
| Communicable Diseases, Inflammation | Altered Intercellular Communication | Suppurative inflammation was observed in 1 patient, and infection occurred after bone reposition. | 28479048 |
| Tumor necrosis, Inflammation | Altered Intercellular Communication | Toll-like receptor 3 (TLR3) is involved in type I interferon-b (IFN-b) via TIR-domain-containing adapter-inducing interferon-b (TRIF) and Tumor necrosis factor receptor-associated factor 3 (TRAF3), culminating in inflammation and immunity reactions. | 28479387 |
| Necrotizing granulomatous inflammation | Altered Intercellular Communication | Cerebral Granulomatous Inflammation Secondary to Hydrophilic Polymer Embolization Following Thrombectomy. | 28479590 |
| Inflammation, Trachoma | Altered Intercellular Communication | trachomatous inflammation, follicular and/or intense, indicative of active trachoma. | 28479620 |
| Inflammation, "Alzheimers Disease | Altered Intercellular Communication | Aerobic exercise improves quality of life, psychological well-being and systemic inflammation in subjects with Alzheimer's disease. | 28479898 |
| Inflammation | Altered Intercellular Communication | Cardamom could improve some parameters of inflammation and oxidative stress in pre-diabetic subjects. | 28480505 |
| Inflammation | Altered Intercellular Communication | Thus it may be useful in reducing complications associated with inflammation and oxidative stress in these patients. | 28480505 |
| Inflammation | Altered Intercellular Communication | The purpose of this study was to quantify multifidus tissue composition and structure, inflammation, vascularity, and degeneration in individuals with chronic degenerative lumbar spine pathology. | 28480978 |
| Inflammation, Muscle degeneration, Muscle Fibers, Slow-Twitch | Altered Intercellular Communication | Relative fractions of muscle, adipose, and extracellular matrix were quantified along with muscle fiber type and cross-sectional area (CSA) and markers of inflammation, vascularity, satellite cell density, and muscle degeneration. | 28480978 |
| Inflammation, Muscle degeneration | Altered Intercellular Communication | High levels of muscle degeneration, inflammation, and decreased vascularity were commonly seen in human multifidus biopsies of individuals with lumbar spine pathology in comparison to normative data. | 28480978 |
| Inflammation, Acute inflammation | Altered Intercellular Communication | C1M (71.2+-26.1 vs 46.2+-6.2 nmol/L [P<.001]), C3M (31.6+-3.9 vs 26.1+-1.6 nmol/L [P=.002] and Pro-C5 levels (1171.7+-171.5 vs 909.6+-80.4 nmol/L [P=.002]) were higher in patients with active inflammation vs without active inflammation. | 28481042 |
| Inflammation, Crohn Disease | Altered Intercellular Communication | Active inflammation in Crohn's disease is characterised by increased formation of type V collagen and increased matrix metalloproteinase mediated breakdown of type I, III collagen. | 28481042 |
| ARCN1 gene, Inflammation, Chronic Obstructive Airway Disease | Altered Intercellular Communication | Systemic inflammation is an integral part of chronic obstructive pulmonary disease (COPD), and air pollution is associated with cardiorespiratory mortality, yet the interrelationships are not fully defined. | 28481326 |
| Inflammation, Cardiovascular Diseases | Altered Intercellular Communication | These findings raise the possibility that the interplay between air pollution and systemic inflammation may differ between post-BD airflow obstruction and cardiovascular diseases. | 28481326 |
| Communicable Diseases, Fibrosis Assessment, Inflammation | Altered Intercellular Communication | Multiple-Breath Washout Outcomes Are Sensitive to Inflammation and Infection in Children with Cystic Fibrosis. | 28481640 |
| Communicable Diseases, Upper Respiratory Infections, Cystic Fibrosis | Altered Intercellular Communication | The lung clearance index is increased in the presence of lower respiratory tract inflammation and infection in infants with cystic fibrosis; however, the associations during the preschool years are unknown. | 28481640 |
| Communicable Diseases, Upper Respiratory Infections, Cystic Fibrosis | Altered Intercellular Communication | We assessed the ability of the lung clearance index to detect the presence and extent of lower respiratory tract inflammation and infection in preschool children with cystic fibrosis. | 28481640 |
| Communicable Diseases, Fibrosis Assessment | Altered Intercellular Communication | Children with cystic fibrosis also underwent bronchoalveolar lavage fluid collection for detection of lower respiratory tract inflammation and infection. | 28481640 |
| Airway structure, Fibrosis Assessment, Respiratory Tract Infections | Altered Intercellular Communication | In cystic fibrosis, the lung clearance index was elevated in individuals with lower respiratory tract infections (difference compared with uninfected [95% confidence interval], 0.62 [0.06, 1.18]) and correlated with the extent of airway inflammation. | 28481640 |
| Airway structure, Communicable Diseases, Cystic Fibrosis | Altered Intercellular Communication | These data suggest that the lung clearance index may be a useful surveillance tool for monitoring the presence and extent of lower airway inflammation and infection in preschool children with cystic fibrosis. | 28481640 |
| Intraocular inflammation | Altered Intercellular Communication | Improvement in intraocular inflammation was seen in all 24 eyes, with median best-corrected visual acuity (BCVA) increasing from 20/50 to 20/20, after a mean follow-up of 5.3 months. | 28481679 |
| Inflammation, Coronary Artery Disease | Altered Intercellular Communication | Limited prospective data have been reported regarding the impact of carotid inflammation on cardiovascular events in patients with coronary artery disease (CAD). | 28482222 |
| Inflammation, "Alzheimers Disease", Data types - Address | Altered Intercellular Communication | Microglial dysfunction and inflammation have recently been shown to be related to the development of Alzheimer's disease (AD). | 28482637 |
| neutrophilic, Inflammation, Bacterial Infections | Altered Intercellular Communication | Bacterial infection may influence corticosteroid responsiveness by altering the profile of neutrophilic and eosinophilic inflammation. | 28482840 |
| Inflammation, Neoplasms | Altered Intercellular Communication | Systemic inflammation and nutritional status are strongly associated with tumor progression. | 28483664 |
| Malignant Neoplasms | Altered Intercellular Communication | Inflammation-based prognostic scores, such as the Glasgow Prognostic Score (GPS), reflect these states and are predictive in patients with several types of advanced cancers. | 28483664 |
| Inflammation, Coronary Artery Disease | Altered Intercellular Communication | Last, modulation of target organ inflammation (eg, skin) was associated with an improvement in NCB at 1 year, suggesting that control of remote sites of inflammation may translate into reduced coronary artery disease risk. | 28483812 |
| Chronic infectious disease, Inflammation | Altered Intercellular Communication | Chronic infection and associated inflammation have long been suspected to promote human carcinogenesis. | 28483840 |
| Inflammation, CEL gene, Polyneuropathy | Altered Intercellular Communication | The relationship between familial amyloid polyneuropathy (FAP), which is caused by mutated transthyretin (TTR), and inflammation has only recently been noted. | 28484271 |
| Inflammation, CEL gene | Altered Intercellular Communication | In conclusion, FAP carriers and patients are in an inflammatory state, with the presence of mutated TTR being a trigger of inflammation, especially in FAP carriers. | 28484271 |
| Inflammation, Necrosis | Altered Intercellular Communication | The induced inflammation and necrosis after CRT were also investigated. | 28485348 |
| Nasal Polyps, Chronic sinusitis, Helper-Inducer T-Lymphocyte | Altered Intercellular Communication | P-glycoprotein (P-gp) drives type-2 helper T-cell inflammation in chronic rhinosinusitis with nasal polyps (CRSwNP) through unknown posttranslational mechanisms of overexpression. | 28485529 |
| Arthritis, Gout | Altered Intercellular Communication | Gout commonly involves joint inflammation, and clinical epidemiological studies on involved tendons are scant. | 28486089 |
| Inflammation, Bipolar Disorder | Altered Intercellular Communication | Depressive symptom profiles, cardio-metabolic risk and inflammation: Results from the MIDUS study. | 28486177 |
| Inflammation | Altered Intercellular Communication | Our results suggested that a local pulmonary administration of heparin through nebulization may be able to reduce inflammation in the lung; however, further studies are needed to confirm this hypothesis. | 28486961 |
| Atrial Fibrillation, Acute inflammation, Atrial Fibrillation by ECG Finding | Altered Intercellular Communication | Atrial fibrillation (AF) is the most frequent complication of surgery performed on cardiopulmonary bypass (CPB) and recent work associates CPB with postoperative inflammation. | 28487062 |
| Inflammation | Altered Intercellular Communication | If mtDNA is directly involved in cardiac inflammation, mtDNA-induced toll-like receptor-9 (TLR9) signalling could also be targeted therapeutically. | 28487062 |
| Inflammation, Pneumonia | Altered Intercellular Communication | The diagnosis of pneumonia was based on radiological evidence of chest inflammation and clinical symptoms. | 28487142 |
| Inflammation | Altered Intercellular Communication | The chemokine receptor CCR5 plays roles in the trafficking of effector cells towards the site of inflammation. | 28487238 |
| Prostate carcinoma, prostatitis | Altered Intercellular Communication | However, their effect on histologic prostate inflammation is not well understood, particularly among men at increased prostate cancer risk but with a negative prostate biopsy. | 28487295 |
| Inflammation, Acute inflammation | Altered Intercellular Communication | Statin users had reduced presence of chronic inflammation (OR, 0.81; 95% CI, 0.69-0.95) and were less likely to have severe chronic (OR, 0.80; 95% CI, 0.68-0.95) and severe acute inflammation (OR, 0.73; 95% CI, 0.53-1.00), relative to non-users. | 28487295 |
| Inflammation, Prostate carcinoma, prostatitis | Altered Intercellular Communication | Given the possible role for inflammation in prostate cancer, the inverse association between statins and prostate inflammation suggests a mechanism linking statins with lower advanced prostate cancer risk. | 28487295 |
| Inflammation, Dental Plaque | Altered Intercellular Communication | Inflammation and intraplaque neovascularization are acknowledged to be 2 features of plaque vulnerability, although their temporal expression and their respective value in predicting clinical events are poorly understood. | 28487317 |
| Inflammation, Dental Plaque | Altered Intercellular Communication | To determine their respective temporal associations, we conducted a comprehensive assessment of inflammation and intraplaque neovascularization in the carotid plaque of symptomatic and asymptomatic patients. | 28487317 |
| Inflammation | Altered Intercellular Communication | Plaque 18F-fluorodeoxyglucose-uptake, indicative of inflammation, was measured by calculating the target:background ratio. | 28487317 |
| Inflammation, Dental Plaque | Altered Intercellular Communication | Inflammation and intraplaque neovascularization are not systematically associated in carotid plaques, suggesting a temporal separation between the 2 processes. | 28487317 |
| Refractory anemias, leukemia | Altered Intercellular Communication | CONCLUSIONS While anti-CD20 antibodies have a clear role in the treatment of leukemia and inflammatory conditions, the success of obinutuzumab in RA has not been fully evaluated. | 28487504 |
| Inflammation, Imprinting (Psychology), Obesity | Altered Intercellular Communication | The maternal inflammation status during pregnancy has been associated with metabolic imprinting and obesity development in the child. | 28487553 |
| Cholangiocarcinoma, Biliary Intraepithelial Neoplasia | Altered Intercellular Communication | Biliary intraepithelial neoplasia (BilIN) is a precursor of cholangiocarcinoma (CC) and it has been associated with several chronic inflammatory conditions. | 28490009 |
| Inflammation, Brain Injuries | Altered Intercellular Communication | Targeting peripherally derived, or resident inflammatory, cells that are rapid responders to brain injury is promising, but complex, given that the contribution of inflammation to exacerbation versus improved recovery varies with time post-injury. | 28490277 |
| Crohn Disease, Inflammation | Altered Intercellular Communication | Crohn's Disease (CD) is a relapsing inflammation of the gastrointestinal tract that affects a young working age population and is increasing in developing countries. | 28490445 |
| Inflammatory Bowel Diseases, Inflammation, Rheumatoid Arthritis, Ulcerative Colitis | Altered Intercellular Communication | DAVID 6.7 (NIH) was used for functional annotation analysis of detected proteins and immunoblotting and multiple reaction monitoring (MRM) to verify a priori findings in a secondary independent cohort of complicated CD (CCD), uncomplicated inflammatory CD (ICD), Th1/17 pathway inflammation controls (rheumatoid arthritis), inflammatory bowel disease controls (ulcerative colitis), and healthy controls. | 28490445 |
| Inflammation, Torsades de Pointes | Altered Intercellular Communication | Systemic inflammation as a novel QT-prolonging risk factor in patients with torsades de pointes. | 28490617 |
| Inflammation, Long QT Syndrome | Altered Intercellular Communication | Increasing evidence indicates systemic inflammation as a new potential cause of acquired long QT syndrome (LQTS), via cytokine-mediated changes in cardiomyocyte ion channels. | 28490617 |
| Inflammation, TDP biosynthetic process | Altered Intercellular Communication | Since classical risk factors cannot fully explain TdP events in a number of patients, we hypothesised that systemic inflammation may represent a currently overlooked risk factor contributing to TdP development in the general population. | 28490617 |
| Inflammation, TDP biosynthetic process | Altered Intercellular Communication | The data are first to show that systemic inflammation via elevated IL-6 levels may represent a novel QT-prolonging risk factor contributing to TdP occurrence in the presence of other classical risk factors. | 28490617 |
| Inflammation | Altered Intercellular Communication | In conclusion, elevated WBC counts independently predict the risk of new-onset PAD in a Chinese community-based population, supporting the hypothesis that systemic inflammation plays an important role in PAD development. | 28490753 |
| Airway structure, ARCN1 gene | Altered Intercellular Communication | Interleukin (IL)-1b and IL-17 are the key mediators of neutrophilic airway inflammation in COPD. | 28490868 |
| Airway structure, ARCN1 gene | Altered Intercellular Communication | In conclusion, elevated serum IL-1b and IL-17 levels may be used as a biomarker for indicating persistent neutrophilic airway inflammation and potential ongoing exacerbation of COPD. | 28490868 |
| Airway structure, ARCN1 gene, Chronic Obstructive Airway Disease | Altered Intercellular Communication | Measurements of eosinophils in induced sputum and fractional exhaled nitric oxide (FeNO) are noninvasive biomarkers for assessing airway inflammation phenotypes in chronic obstructive pulmonary disease (COPD). | 28490872 |
| Inflammation, Chronic gastritis | Altered Intercellular Communication | Curcumin can be a useful supplement to improve chronic inflammation and prevention of carcinogenic changes in patients with chronic gastritis associated by H. pylori. | 28492711 |
| Psoriatic Juvenile Idiopathic Arthritis, Inflammation | Altered Intercellular Communication | Recent studies indicate the presence of systemic inflammation in psoriatic patients, and this inflammatory status is significantly associated with a range of comorbidities. | 28493493 |
| Inflammation, Arthritis | Altered Intercellular Communication | MPV value was negatively associated with the presence of arthritis, but its association with inflammation was less clear than that of NLR or PLR. | 28493493 |
| Psoriatic Juvenile Idiopathic Arthritis, Inflammation | Altered Intercellular Communication | Altogether, these results indicate that both NLR and PLR may be useful markers to evaluate systemic inflammation in psoriatic patients. | 28493493 |
| Arthralgia, Inflammation, Degenerative polyarthritis | Altered Intercellular Communication | SP and NK1 receptors have been implicated in joint pain, inflammation and damage in animal models and human studies of osteoarthritis (OA). | 28493529 |
| Inflammation | Altered Intercellular Communication | Genomic biomarkers of prenatal intrauterine inflammation in umbilical cord tissue predict later life neurological outcomes. | 28493900 |
| Inflammation | Altered Intercellular Communication | Genes that were differentially expressed across four indicators of intrauterine inflammation were identified and their functions examined. | 28493900 |
| Inflammation, ETV3 wt Allele | Altered Intercellular Communication | Postmenopausal status could predict MetS, with inflammation and oxidative stress arising from an unhealthy lifestyle potentially increasing cardiovascular risk. | 28494104 |
| Pain Distress Question, Diabetic dermopathy, Inflammation, Diabetes Mellitus, Non-Insulin-Dependent | Altered Intercellular Communication | Influence of low-level laser on pain and inflammation in type 2 diabetes mellitus with diabetic dermopathy - A case report. | 28494177 |
| Inflammation, Chronic sinusitis, Craniosynostosis, Dysbiosis | Altered Intercellular Communication | Chronic rhinosinusitis (CRS) is a heterogeneous disease characterized by persistent sinonasal inflammation and sinus microbiome dysbiosis. | 28494786 |
| Inflammation, Postexertional fatigue, Anxiety, CTCAE 3.0, Depression, CTCAE, Fatigue | Altered Intercellular Communication | Clinical markers consisted of questionnaire scores for symptoms of post-exertional malaise, inflammation, fatigue, depression and trait anxiety, as well as activity recordings. | 28494812 |
| Inflammation, B-Cell Differentiation | Altered Intercellular Communication | Gene set enrichment analyses suggested impairment of B cell differentiation and survival, as well as enhancement of innate antiviral responses and inflammation in the CFS group. | 28494812 |
| Inflammation, B-Cell Differentiation, Chronic Fatigue Syndrome | Altered Intercellular Communication | Adolescent CFS is characterized by differential gene expression pattern in whole blood suggestive of impaired B cell differentiation and survival, and enhanced innate antiviral responses and inflammation. | 28494812 |
| Refractory anemias, Rheumatoid Arthritis, Arthritis, Autoimmune Diseases | Altered Intercellular Communication | Rheumatoid arthritis (RA) is a systemic autoimmune disease whose main feature is persistent joint inflammation. | 28495399 |
| Inflammation | Altered Intercellular Communication | Toll-like receptors (TLRs) play critical roles in the activation of innate and adaptive immune responses, and influence the activity of NFkB, a key player in chronic inflammation. | 28495399 |
| Inflammation, Hemorrhage, Dental Plaque | Altered Intercellular Communication | There was no significant difference in probing depth, peri-implant inflammation, bleeding, and plaque between the two groups (p > 0.05), while the calculus was significantly more observed in ISCRPD group than in IARPD group (p < 0.05). | 28497062 |
| Inflammation, Dental Plaque | Altered Intercellular Communication | Chitosan brush could be a reliable instrument for the professionally administered plaque removal and resolution of clinical signs of initial stages of peri-implant inflammation. | 28497660 |
| Inflammation, Bronchiectasis, Tissue damage, Communicable Diseases, Malignant Neoplasms | Altered Intercellular Communication | The spectrum of pulmonary manifestations in PIDs is broad, and includes acute and chronic infection, structural abnormalities (eg, bronchiectasis), malignancy and dysregulated inflammation resulting in tissue damage. | 28497675 |
| Inflammation, Psoriasis | Altered Intercellular Communication | Serum YKL-40 as a potential biomarker of inflammation in psoriasis. | 28498006 |
| Psoriatic Juvenile Idiopathic Arthritis, Inflammation, Psoriasis | Altered Intercellular Communication | YKL-40 might be a biomarker of psoriasis and inflammation in psoriatic patients, but not a reliable indicator of metabolic conditions, severity of psoriasis nor efficacy of the treatment. | 28498006 |
| Inflammation, Clear cell adenocarcinoma of ovary | Altered Intercellular Communication | Prognostic significance and predictors of the system inflammation score in ovarian clear cell carcinoma. | 28498842 |
| Association of Community Cancer Centers, Inflammation, Adenocarcinoma, Clear Cell | Altered Intercellular Communication | Chronic inflammation is a well-known epidemiologic factor of ovarian clear cell carcinomas (OCCC), but has an uncertain role in prognosis. | 28498842 |
| Association of Community Cancer Centers, Inflammation | Altered Intercellular Communication | We developed a systemic inflammation score (SIS) based on preoperative serum albumin and neutrophil-to-lymphocyte ratio (NLR) for predicting progression-free survival (PFS) and overall survival (OS) in OCCC patients. | 28498842 |
| Association of Community Cancer Centers, Inflammation | Altered Intercellular Communication | We have developed a system inflammation score for predicting prognosis of OCCC patients, which may help stratify patients for postsurgical management. | 28498842 |
| Intraocular inflammation | Altered Intercellular Communication | After an 8- to 10-week hiatus, they were switched over to ranibizumab and aflibercept, respectively, following which they developed a second episode of intraocular inflammation, treated similarly. | 28499055 |
| Inflammation, Acute heart failure | Altered Intercellular Communication | Prealbumin is a maker of nutritional status and inflammation of potential prognostic value in acute heart failure (HF). | 28499710 |
| Inflammation, physiopathological, Nerve Degeneration | Altered Intercellular Communication | The factors associated with tau in serum may promote neurodegeneration and alter the permeability of the Blood Brain Barrier through chronic inflammation and vascular dysfunction. | 28499950 |
| vascular inflammations, Atherosclerosis | Altered Intercellular Communication | Immunological activity and vascular inflammation during atherosclerosis can be modulated by autoimmune responses against self-antigens, according to changeable risk factors (cholesterol, oxidized low-density lipoprotein (ox-LDL) in the vascular wall, fatty acids, etc. | 28500763 |
| Anorexia Nervosa, Amenorrhea | Altered Intercellular Communication | To measure, for the first time, serum kisspeptin concentrations in adolescent females with anorexia nervosa (AN) and associated amenorrhea, and investigate potential correlations of kisspeptin with anthropometric, bone and hormonal data. | 28500826 |
| Thyroid dysfunction, Autoimmune Thyroid Disease Pathway | Altered Intercellular Communication | Thyroid dysfunction affects the skeleton, and autoimmune thyroid disease, manifesting as a chronic inflammatory condition, may be an important contributing factor to impaired bone quality in these patients. | 28500828 |
| Inflammation, AHSG protein, human | Altered Intercellular Communication | Fetuin-A and adiponectin, major hepatokine and adipokine respectively, have been implicated in systematic inflammation. | 28500919 |
| Inflammation, Neoplasms | Altered Intercellular Communication | Gelatinases, Matrix MetalloProteinase(MMP)-2 and MMP-9, belong to zinc-dependent endopeptidases involved in several physiological and pathological processes including inflammation and tumor development. | 28500926 |
| Edema of eyelid, Inflammation, Orofacial Pain | Altered Intercellular Communication | Her main symptoms were orofacial pain, eye redness, inflammation of the eyelids, and eyelid edema. | 28501097 |
| Inflammation, Virus Diseases | Altered Intercellular Communication | While most human T cells express the CD28 costimulatory molecule constitutively, it is well known that age, inflammation, and viral infection can drive the generation of CD28null T cells. | 28502091 |
| Inflammation, Bronchiectasis | Altered Intercellular Communication | Systemic inflammation in bronchiectasis is poorly studied in relation to aetiology and severity. | 28502416 |
| Inflammation, Bronchiectasis | Altered Intercellular Communication | We hypothesized that molecular patterns of inflammation may define particular aetiology and severity groups in bronchiectasis. | 28502416 |
| Unknown (origin) (qualifier value), Post-infectious disorder, Inflammation | Altered Intercellular Communication | There were generally similar patterns of inflammation in patients with idiopathic and post-infectious disease. | 28502416 |
| Acute inflammation | Altered Intercellular Communication | We hypothesized that high-dose sodium selenite supplementation can attenuate the postoperative inflammation and might, therefore, improve clinical outcome. | 28502744 |
| Inflammation, Peripheral muscle fatigue | Altered Intercellular Communication | Peripheral muscle fatigue in hospitalised geriatric patients is associated with circulating markers of inflammation. | 28502777 |
| Inflammation, Obesity | Altered Intercellular Communication | Flavonoid intake is inversely associated with obesity and C-reactive protein, a marker for inflammation, in US adults. | 28504712 |
| Blindness, Inflammation, Uveitis | Altered Intercellular Communication | Uveitis, defined as inflammation of the uveal tract, may cause blindness in both young and middle-aged people. | 28505077 |
| Obesity | Altered Intercellular Communication | Obesity is associated with metabolic and hormonal dysregulation as well as adipokines increase. | 28505082 |
| Inflammation, Atrophic | Altered Intercellular Communication | Inflammation, Amyloid, and Atrophy in The Aging Brain: Relationships with Longitudinal Changes in Cognition. | 28505968 |
| Inflammation, Cerebral atrophy | Altered Intercellular Communication | Our results suggest a role for inflammation in brain atrophy and cognitive changes in cognitively normal older adults, which partly depended on Ab accumulation. | 28505968 |
| Genus Mycobacterium, Inflammation, Infection | Altered Intercellular Communication | An association between pulmonary Mycobacterium avium-intracellulare complex infections and biomarkers of Th2-type inflammation. | 28506264 |
| Inflammation, Ichthyosis Bullosa of Siemens, Irritable Bowel Syndrome | Altered Intercellular Communication | A growing body of evidence suggests a possible role for low-grade inflammation in the pathogenesis of irritable bowel syndrome (IBS). | 28506572 |
| Inflammation, Atrial Fibrillation by ECG Finding | Altered Intercellular Communication | Increased inflammation biomarkers plasma levels, including C-reactive protein (CRP), have been associated with the initiation and perpetuation of atrial fibrillation (AF). | 28506639 |
| Inflammation | Altered Intercellular Communication | However, it is not known whether an increased CRP plasma level, without concomitant inflammation, is sufficient to induce AF. | 28506639 |
| Tubulointerstitial fibrosis, Nephritis, diabetic | Altered Intercellular Communication | Lysophosphatidic acid (LPA) and lysophosphatidylcholine (LPC) are lysophospholipid mediators shown to accumulate in kidney and to promote renal inflammation and tubulo-interstitial fibrosis in diabetic rodent models. | 28506691 |
| Tubulointerstitial fibrosis, Kidney damage, Nephritis, Diabetes Mellitus | Altered Intercellular Communication | Because LPA and LPC are known to promote renal inflammation and tubulo-interstitial fibrosis, their increased production in DN could participate to the development of kidney damage associated with diabetes. | 28506691 |
| Inflammation, Observation Method - Coagulation | Altered Intercellular Communication | Unhealthy older octogenarians show increased levels of several plasma proteins of inflammation and coagulation. | 28506697 |
| Prostate carcinoma | Altered Intercellular Communication | Experimental studies have suggested that nonsteroidal anti-inflammatory drugs (NSAIDs) may improve prostate cancer survival through antithrombotic and anti-inflammation mechanisms. | 28507039 |
| vascular inflammations, Non-alcoholic Fatty Liver Disease | Altered Intercellular Communication | Non-alcoholic fatty liver disease, vascular inflammation and insulin resistance are exacerbated by TRAIL deletion in mice. | 28507343 |
| Inflammation, Fibrosis Assessment | Altered Intercellular Communication | Hepatic triglyceride content, inflammation and fibrosis were increased with TRAIL-deletion, with elevated expression of genes regulating lipogenesis and gluconeogenesis. | 28507343 |
| Inflammation, Fibrosis Assessment | Altered Intercellular Communication | In vitro, palmitate treatment of hepatocytes increased lipid accumulation, inflammation and fibrosis, with TRAIL mRNA significantly reduced. | 28507343 |
| vascular inflammations, Non-alcoholic Fatty Liver Disease | Altered Intercellular Communication | These findings suggest that TRAIL protects against insulin resistance, NAFLD and vascular inflammation. | 28507343 |
| Inflammation, Obesity | Altered Intercellular Communication | Increased adipose tissue expression of IL-18R and its ligand IL-18 associates with inflammation and insulin resistance in obesity. | 28508444 |
| Inflammation, Fibrosis Assessment, Stenosis, Food impaction, "Extra-osseous Ewings sarcoma | Altered Intercellular Communication | Active inflammation (eosinophils >15 eos/high-power field), histological lamina propria fibrosis, and various features of a fibrotic phenotype (stricture, food impaction, circumferential rings on endoscopy) were associated with decreased distensibility within the EoE cohort. | 28508868 |
| Allergic asthma | Altered Intercellular Communication | We sought to characterize the involvement of NADPH oxidase in allergic asthma by studying the role of CYBA (p22phox) in human asthma and murine house dust mite (HDM)-induced allergic airway inflammation. | 28510479 |
| Refractory anemias, Inflammation, Degenerative polyarthritis | Altered Intercellular Communication | Regenerative medicine can be expected for RA patients with the inflammation well-controlled as well as OA patients and transplantation of synovial MSCs would also be a possible therapeutic treatment. | 28511664 |
| Inflammation, Cardiovascular Diseases, Cyclophosphamide/Vincristine/Dacarbazine Regimen, Endothelial dysfunction, Chronic Kidney Diseases | Altered Intercellular Communication | Chronic kidney disease (CKD) is a major risk factor for cardiovascular disease (CVD), partly due to endothelial dysfunction and chronic inflammation. | 28511692 |
| Inflammation, Chronic Kidney Diseases, Atherosclerosis | Altered Intercellular Communication | Paricalcitol treatment for 12 weeks in patients with moderate CKD reduces cytokines and micro RNAs involved in atherosclerosis and inflammation. | 28511692 |
| Autoimmune Diseases, Inflammation | Altered Intercellular Communication | Regulatory T cells (Tregs) play a role in the suppression of inflammation in autoimmune diseases, and lymphocyte activation gene 3 (LAG3) was reported as a marker of interleukin (IL)-10-producing Tregs. | 28511719 |
| Airway structure, Craniosynostosis, Asthma, Chronic sinusitis, Rhinitis | Altered Intercellular Communication | Despite the close linkage between rhinitis, chronic rhinosinusitis (CRS) and asthma, relevant biomarkers of both upper and lower airway inflammation are rare. | 28513250 |
| Herpes Simplex Infections, Granulomatous inflammation | Altered Intercellular Communication | Coexistence of herpes simplex virus infection in microsporidial stromal keratitis associated with granulomatous inflammation. | 28513490 |
| Herpes Simplex Infections, Granulomatous inflammation, Keratitis | Altered Intercellular Communication | Granulomatous inflammation, in microsporidial stromal keratitis, is never well described, and the authors in this article aim to describe the presence of granulomatous inflammation in microsporidial stromal keratitis, in patients with associated herpes simplex virus (HSV) keratitis. | 28513490 |
| Granulomatous inflammation | Altered Intercellular Communication | There was evidence of diffuse stromal necrosis with markedly severe degree of polymorphonuclear leukocytic infiltrates, with granulomatous inflammation in 42% of cases. | 28513490 |
| Granulomatous inflammation | Altered Intercellular Communication | Review of medical records revealed much severe clinical presentations in patients with granulomatous inflammation, in comparison to cases without granulomatous inflammation. | 28513490 |
| Granulomatous inflammation | Altered Intercellular Communication | The authors hereby recommend that severe clinical presentation in patients with microsporidial stromal keratitis, markedly dense polymorphonuclear leukocytic infiltrates or the presence of granulomatous inflammation on the histopathological examination, should be investigated further for the presence of HSV-1 DNA for better patient management and good visual outcome. | 28513490 |
| Tumor necrosis, Inflammation, Ascites, Malignant Neoplasms | Altered Intercellular Communication | Ascites with EOC cells also had higher levels of tumor necrosis factor (TNF)-a, suggesting inflammation related to the malignancy. | 28513532 |
| Inflammation | Altered Intercellular Communication | The mechanisms that enable preservation of gut mucosal integrity during persistent viral replication and inherent inflammation remain unclear. | 28513595 |
| niobium | Altered Intercellular Communication | No change in saliva hormonal concentrations was found during the experiment for both groups, whereas RPE responses were increased in the Good Ap group under Ap vs. NB conditions. | 28514808 |
| Brachydactyly, Midface retrusion, Intellectual Disability | Altered Intercellular Communication | His mother shared some characteristic features, such as midfacial hypoplasia and severe brachydactyly, but did not show short stature, intellectual disability or hormonal resistance. | 28515031 |
| Inflammation, Heart failure, Anemia, Chronic Kidney Diseases | Altered Intercellular Communication | Furthermore, anemia, insulin resistance, inflammation, and poor glycemic control are independent risk factors for the development of heart failure among patients with chronic kidney disease. | 28515118 |
| Hypocalciuria, Parathyroiditis, Hypercalcemia, CTCAE | Altered Intercellular Communication | Here, we describe a patient with acquired parathyroid hormone (PTH)-dependent hypercalcemia with associated hypocalciuria, found to have true lymphocytic parathyroiditis on histopathology, and circulating anti-CaSR antibodies in serum. | 28515208 |
| Inflammation, Pneumonia | Altered Intercellular Communication | The elderly, who manifest a general decline in immune function and higher basal levels of inflammation, are at increased risk of developing pneumococcal pneumonia. | 28516066 |
| Communicable Diseases, Pneumonitis, Pneumonia | Altered Intercellular Communication | Using an aged mouse infection model, we previously showed that oral supplementation with the alpha-tocopherol form of vitamin E (a-Toc) decreases pulmonary inflammation, in part by modulating neutrophil migration across lung epithelium into alveolar spaces, and reverses the age-associated decline in resistance to pneumococcal pneumonia. | 28516066 |
| Pneumonitis | Altered Intercellular Communication | We found that basal levels of pneumococcal-induced transepithelial migration by PMNs from young or elderly donors were indistinguishable, suggesting that the age-associated exacerbation of pulmonary inflammation is not due to intrinsic properties of PMNs of elderly individuals but rather may reflect the inflammatory milieu of the aged lung. | 28516066 |
| Rheumatoid Arthritis, Tenosynovitis | Altered Intercellular Communication | Tenosynovitis in rheumatoid arthritis patients on biologic treatment: involvement and sensitivity to change compared to joint inflammation. | 28516887 |
| Refractory anemias, Inflammation | Altered Intercellular Communication | Extensor carpi ulnaris (ECU) and tibialis posterior (TP) tendons are often involved in RA and the present aim was to examine by ultrasound (US) their frequency of inflammation and sensitivity to change in comparison to joint involvement as well as clinical examinations. | 28516887 |
| Pancreatic carcinoma | Altered Intercellular Communication | Together with the existing literature on this topic, our results suggest that reproductive and hormonal exposures are unlikely to play an important role in the etiology of pancreatic cancer. | 28521283 |
| Inflammation, Depression, CTCAE | Altered Intercellular Communication | Depression, Inflammation, and Physiological Risk in Late Life: A National Longitudinal Study. | 28521620 |
| Inflammation, Depression, CTCAE | Altered Intercellular Communication | Inflammation was indicated by C-reactive protein and depression by the CES-D scale. | 28521620 |
| Cessation of life | Altered Intercellular Communication | Family Member Deaths in Childhood Predict Systemic Inflammation in Late Life. | 28521621 |
| Inflammation | Altered Intercellular Communication | Biological and epidemiological evidence has linked early-life psychosocial stress with late-life health, with inflammation as a potential mechanism. | 28521621 |
| Cessation of life, Inflammation | Altered Intercellular Communication | We report here the association between familial death in childhood and adulthood and increased levels of high-sensitivity C-reactive protein (CRP), a marker of systemic inflammation. | 28521621 |
| Inflammation | Altered Intercellular Communication | The role of dietary antioxidants and plasma oxidant-antioxidant status in low-grade chronic inflammation and adipocytokine levels is not established yet. | 28521871 |
| Inflammation, effusion | Altered Intercellular Communication | Vascular permeability, effusions, inflammation, and other mechanisms may also play a role in the accumulation of radioactive iodine. | 28522155 |
| ARCN1 gene, Inflammation | Altered Intercellular Communication | In conclusion, oxidative stress reduces PTEN protein levels, which may result in increased PI3K signaling and amplification of inflammation in COPD. | 28522564 |
| Granulomatous inflammation, Infiltration | Altered Intercellular Communication | Biopsy of his left superficial temporal artery revealed a granulomatous inflammation with multinucleated giant cell infiltration, so he was diagnosed with GCA with consecutive left A-AION. | 28523333 |
| Retinal Degeneration, Intraocular inflammation | Altered Intercellular Communication | We retrospectively reviewed charts of patients without a family history of inherited retinal degenerations who presented with retinal pigment changes and signs of past or present intraocular inflammation. | 28523457 |
| Inflammation, Intraocular inflammation | Altered Intercellular Communication | Four of five cases presented with active inflammation, and the remaining case showed evidence of active intraocular inflammation during follow-up. | 28523457 |
| Inflammation, Uveitis | Altered Intercellular Communication | Careful review of possible past uveitis history, detailed examination of signs of past or present inflammation and ancillary testing, with FA often being most helpful, are required for the correct diagnosis. | 28523457 |
| Pigmentation, Inflammation | Altered Intercellular Communication | This is important, because intervention can prevent further damage if the cause of the pigmentary changes is destructive inflammation. | 28523457 |
| Infertility, Inflammation | Altered Intercellular Communication | Is male factor infertility associated with midlife low-grade inflammation? | 28523952 |
| Infertility, Inflammation | Altered Intercellular Communication | Male factor infertility is associated with an increased risk of disease and mortality, which has been related to markers of chronic systemic inflammation. | 28523952 |
| Inflammation | Altered Intercellular Communication | Inflammation was considered to play a role in the whole process of AS. | 28524828 |
| Acute inflammation, Hypertrophy, Enlarged kidney | Altered Intercellular Communication | We identified the ultrasound (US), magnetic resonance (MR), and CT-signs of acute renal inflammation at different stages of the process.The main us-signs were decreased mobility of the kidney, its enlargement, thickened parenchyma, hydrophilic parenchyma and an impairment of corticomedullary differentiation.The typical CT-signs of AP were enlargement of the kidney with its thickened parenchyma and an impairment of corticomedullary differentiation.The main MR-signs of AP were enlargement of the kidney (>12 cm lengthwise), thickened parenchyma (<2 cm in the median segment of the kidney) and an impairment of corticomedullary differentiation. | 28525662 |
| Intraocular inflammation, Fever | Altered Intercellular Communication | Two patients in cohort 4 (2 x 1010 vg) experienced adverse events that were possibly study-drug related: pyrexia and intraocular inflammation that resolved with a topical steroid. | 28526489 |
| Inflammation | Altered Intercellular Communication | Chronic inflammation plays an important role in AF development and interleukin-18 (IL-18) is a pro-inflammatory cytokine. | 28526653 |
| Inflammation, Ischemic stroke | Altered Intercellular Communication | Inflammation, kidney function, and frailty also seemed to be determinants of survival and recovery after an ischemic stroke. | 28526765 |
| Intraocular inflammation | Altered Intercellular Communication | This may be related to intraocular inflammation, which is more limited in chronic than in acute RRD. | 28527031 |
| Inflammation, Coronary Artery Disease | Altered Intercellular Communication | Many coronary artery disease (CAD) patients exhibit chronic low-grade inflammation. | 28527371 |
| Inflammation | Altered Intercellular Communication | Taken together, these results show that lutein has the potential to play a role in resolution of chronic inflammation in CAD patients. | 28527371 |
| Inflammation, "Alzheimers Disease", Memory impairment | Altered Intercellular Communication | Simvastatin ameliorate memory deficits and inflammation in clinical and mouse model of Alzheimer's disease via modulating the expression of miR-106b. | 28528185 |
| Inflammation, Impaired cognition, Presenile dementia, "Alzheimers Disease", Data types - Address, Brain Diseases | Altered Intercellular Communication | Alzheimer's disease (AD) as a neurodegenerative brain disorder is a devastating pathology leading to disastrous cognitive impairments and dementia, and several studies have shown that AD is closely related to the inflammation, so anti-inflammatory treatment may provide therapeutic benefits. | 28528185 |
| Inflammation, Chronic granulomatous disease, Mycoses | Altered Intercellular Communication | Chronic granulomatous disease (CGD) is characterized by recurrent life-threatening bacterial and fungal infections and aberrant inflammation. | 28528201 |
| Cachexia | Altered Intercellular Communication | Models were adjusted for case-mix and malnutrition-inflammation cachexia syndrome (MICS) covariates. | 28528336 |
| UGCG gene, Edema, Cardiac, Inflammation | Altered Intercellular Communication | Potentially, GCS might contribute to increased coronary vascular permeability in TTC, thus dissociating development of myocardial oedema from severity of associated inflammation. | 28528983 |
| Inflammation | Altered Intercellular Communication | Furthermore, obesity-induced inflammation, which affects UA metabolism and MCI onset, might regulate such protective role. | 28529242 |
| Amyotrophic Lateral Sclerosis, Inflammation | Altered Intercellular Communication | Microglial inflammation contributed to reduced FA in ALS, and may contribute to a pro-inflammatory state, but further work is needed to determine their role. | 28529876 |
| Inflammation, Fibrosis Assessment | Altered Intercellular Communication | The angiotensin II, through interaction with angiotensin II type 1 receptor (AGTR1), promotes proliferation, inflammation and fibrosis. | 28530466 |
| Inflammation, Milk, Human, Milk (body substance) | Altered Intercellular Communication | Controlling for age, inflammation, and other covariates, there was no difference in the mean pRBP, mean breast milk VA, prevalence of low pRBP, or prevalence of low milk VA between the pre- and post-fortification surveys. | 28531099 |
| Viral myocarditis, Inflammation | Altered Intercellular Communication | Diagnosis of viral myocarditis is difficult by clinical criteria but facilitated by detection of inflammation and viral genomes in endomyocardial biopsies. | 28531186 |
| Inflammation, Weight decreased, Endothelial dysfunction, Diabetes Mellitus, Non-Insulin-Dependent | Altered Intercellular Communication | Diet-induced weight loss and markers of endothelial dysfunction and inflammation in treated patients with type 2 diabetes. | 28531772 |
| Inflammation, Endothelial dysfunction, Obesity, Overweight, Weight decreased, Diabetes Mellitus, Non-Insulin-Dependent | Altered Intercellular Communication | Diet-induced weight loss reduced the levels of biomarkers of endothelial dysfunction and inflammation in overweight and obese patients with T2D independently of medication use and T2D duration. | 28531772 |
| Inflammation, Obesity | Altered Intercellular Communication | The obesity and inflammation is associated with high REE and when not compensated by adequate intake, may determine an unfavorable clinical outcome in this population. | 28531773 |
| Inflammation, Neoplasm Metastasis, Malignant Neoplasms, Neoplasms | Altered Intercellular Communication | It has been shown that inflammation plays a major role in the treatment of these cancers and inflammatory factors enhance tumor growth, invasion, metastasis, and vascularization. | 28532133 |
| Perifolliculitis | Altered Intercellular Communication | Of 18,196 children aged 1-9 years examined, 1526 (8.4%) had trachomatous inflammation-follicular (TF). | 28532208 |
| ARCN1 gene, Inflammation | Altered Intercellular Communication | Besides the chronic inflammation in the lung compartment, there is also a systemic inflammation present in COPD patients. | 28532454 |
| Inflammation | Altered Intercellular Communication | This systemic inflammation is associated with elevated levels of cytokines in the peripheral blood, but the precise composition is unknown. | 28532454 |
| Inflammation, Venous Insufficiency | Altered Intercellular Communication | The physiopathology could be related to chronic inflammation associated with venous insufficiency and with certain trigger factors. | 28532589 |
| Inflammation, Endothelial dysfunction | Altered Intercellular Communication | Low-grade inflammation, endothelial dysfunction, and platelet hyper-reactivity to agonists are associated with an increased risk of cardiovascular events. | 28533260 |
| Inflammation, Non-Small Cell Lung Carcinoma | Altered Intercellular Communication | Neutrophil-lymphocyte ratio (NLR) is a measure of systemic inflammation that appears prognostic in localized and advanced non-small cell lung cancer (NSCLC). | 28533476 |
| Inflammation, Primary malignant neoplasm | Altered Intercellular Communication | Increased systemic inflammation portends a poorer prognosis in cancer patients. | 28533476 |
| Inflammation, Acute and chronic inflammation | Altered Intercellular Communication | Normalization of acid reflux in both groups was associated with reduction in papillary length, basal cell layer thickness, intercellular space dilatation, and acute and chronic inflammation of squamous epithelium. | 28533674 |
| Muscle Cramp, Inflammation, Arteriovenous fistula, Sleeplessness, Pruritus | Altered Intercellular Communication | Insomnia, muscular cramps and pruritus have low intensity in hemodialysis patients with good dialysis efficiency, low inflammation and arteriovenous fistula. | 28534129 |
| Muscle Cramp, Sleeplessness, Inflammation | Altered Intercellular Communication | Insomnia is associated with muscular cramps and inflammation. | 28534129 |
| Granulomatous inflammation, Tuberculosis | Altered Intercellular Communication | Cytologic diagnoses rendered were tubercular epididymo-orchitis in 15, granulomatous inflammation suggestive of tuberculosis in six and granulomatous inflammation in 19. | 28534708 |
| Inflammation, Labor (Childbirth) | Altered Intercellular Communication | Cell-free DNA, inflammation, and the initiation of spontaneous term labor. | 28536048 |
| Degenerative polyarthritis, Inflammation, Osteoarthritis, Knee | Altered Intercellular Communication | Dietary fibre reduces body weight and inflammation both of which are linked with knee osteoarthritis (OA). | 28536116 |
| Inflammation, Cerebrovascular accident | Altered Intercellular Communication | Together these data show that EVs from stroke patients are proinflammatory in nature and are capable of inducing inflammation in immune cells. | 28536169 |
| ARCN1 gene, Bronchitis | Altered Intercellular Communication | Bronchial inflammation and bacterial load in stable COPD is associated with TLR4 overexpression. | 28536249 |
| ARCN1 gene, Pseudomonas aeruginosa, Bronchitis | Altered Intercellular Communication | Bacterial load did not correlate with inflammatory cells.Bronchial epithelial overexpression of TLR4 and NOD1 in severe/very severe stable COPD, associated with increased bronchial inflammation and P. aeruginosa bacterial load, may play a role in the pathogenesis of COPD. | 28536249 |
| Inflammation, Psoriasis, Thrombophilia | Altered Intercellular Communication | Systemic inflammation and hypercoagulability in psoriasis are related to cardiovascular morbidity. | 28536717 |
| Paraparesis, Spastic, Myelitis, Thrombospondin 1, Tropical Spastic Paraparesis, altretamine/doxorubicin/melphalan protocol | Altered Intercellular Communication | A small number of those infected develop the progressive neurodegenerative disease HTLV-1-associated myelopathy (HAM), also known as tropical spastic paraparesis (TSP), which is characterized by chronic spinal cord inflammation and accompanying myelopathic symptoms. | 28536850 |
| Pain Distress Question, Inflammation, Dysesthesia, Hypotension, CTCAE, Swelling | Altered Intercellular Communication | Post-procedure adverse events included pain (4.0%), swelling and inflammation (2.7%), dysaesthesia (0.7%) and hypotension (0.7%). | 28537343 |
| Inflammation, Hypertensive (finding), Hypertension, CTCAE, Nutritional status | Altered Intercellular Communication | Leukocyte-derived H2S production varied according to the nutritional status of hypertensive subjects, and the H2S/IL-10 signaling pathway may be the junction point among hypertension, disturbance of nutritional status, and inflammation. | 28537431 |
| Inflammation, Cardiovascular Diseases | Altered Intercellular Communication | C-reactive protein (CRP) is a marker of inflammation that has been shown to be predictive of cardiovascular diseases in adults. | 28537577 |
| Inflammation, Metabolic Syndrome X | Altered Intercellular Communication | The association of CRP with metabolic syndrome and its components suggests that inflammation may be useful in assessing cardiovascular risk in adolescents. | 28537577 |
| Pneumonitis | Altered Intercellular Communication | The degree of lung inflammation was observed; the ratio of the thickness of the wall to the external diameter of the pulmonary arterioles (WT%), and the ratio of the area of the wall to that of the pulmonary arterioles (WA%) were calculated. | 28537664 |
| Inflammation | Altered Intercellular Communication | Multivariate regression analysis showed that, compared with the smoking index and inflammation score, TLR4 and MMP-9 expression were the strongest factors affecting the parameters of lung revascularization (WA% and WT%) (p<0.05). | 28537664 |
| Hypertrophy, Inflammation, Neoplasms | Altered Intercellular Communication | MRI of the head and orbit revealed bilateral tubular cystic enlargement of the optic nerve/optic sheath complex with thickening of the optic nerves without inflammation or neoplasm, suggestive of bilateral optic nerve meningocele. | 28538611 |
| vascular inflammations, AAVS1 gene, Vasculitis, CTCAE | Altered Intercellular Communication | Anti-neutrophil cytoplasmic antibody (ANCA)-associated vasculitis (AAV) is systemic vascular inflammation. | 28539536 |
| Inflammation, Psoriasis | Altered Intercellular Communication | Psoriasis is a T helper 1 cell-mediated chronic inflammation. | 28540870 |
| Inflammation, Sarcopenia | Altered Intercellular Communication | weak grip strength (GS) and chronic inflammation have been implicated in the aetiology of sarcopenia in older adults. | 28541423 |
| Inflammation, Dysbiosis | Altered Intercellular Communication | ART-treated subjects concurrently exhibit marked compositional alterations in the gut bacterial microbiota and the degree of dysbiosis correlates with systemic inflammation. | 28541799 |
| Inflammation, Hemorrhage | Altered Intercellular Communication | They presented with severe local inflammation; thus, it was difficult to stop bleeding from the gallbladder bed. | 28541859 |
| Inflammation, Hemorrhage | Altered Intercellular Communication | However, in case of severe local inflammation, there is a greater risk for massive hemorrhage. | 28541859 |
| HD Term Type, Inflammation, Hypoalbuminemia | Altered Intercellular Communication | In the event of oxidative stress and inflammation to which HD patients are exposed, albumin is oxidized and undetected by common laboratory methods, rendering an apparent hypoalbuminemia. | 28542419 |
| Inflammation, Blood Vessel | Altered Intercellular Communication | We wanted to show that these circulating modified oxidized albumin molecules cause direct vascular damage, mediating inflammation. | 28542419 |
| Adenoma | Altered Intercellular Communication | EGCs with pre-existing adenoma show a greater association with H. pylori-related chronic inflammation than those without, which could explain the differences in the characteristics between groups. | 28542582 |
| Inflammation, Primary malignant neoplasm | Altered Intercellular Communication | Systemic inflammation is associated with reduced quality of life and increased symptoms in patients with advanced cancer. | 28542626 |
| Inflammation, Cardiomyopathies | Altered Intercellular Communication | Immune cells participate in cardiomyopathy development either by direct tissue destruction, or by driving inflammation. | 28543170 |
| Inflammation | Altered Intercellular Communication | It has been shown that inflammation may play an important role in the pathophysiology of CI-AKI. | 28543803 |
| Inflammation | Altered Intercellular Communication | Studies have implicated that TLR5 is associated with various diseases such as autoimmune and inflammation related diseases. | 28543911 |
| Inflammation, Hypertensive (finding), Vascular System Injuries | Altered Intercellular Communication | Kallistatin, an endogenous protein, protects against vascular injury by inhibiting oxidative stress and inflammation in hypertensive rats and enhancing the mobility and function of endothelial progenitor cells (EPCs). | 28544111 |
| Steatohepatitis, Inflammation | Altered Intercellular Communication | Novel PPARa agonist MHY553 alleviates hepatic steatosis by increasing fatty acid oxidation and decreasing inflammation during aging. | 28545035 |
| Steatohepatitis, Dyslipidemias, Metabolic Syndrome X, Inflammation | Altered Intercellular Communication | Because hepatic steatosis is closely associated with metabolic syndromes, including insulin resistance, dyslipidemia, and inflammation, numerous efforts have been made to develop compounds that ameliorate it. | 28545035 |
| Steatohepatitis, Inflammation | Altered Intercellular Communication | In conclusion, MHY553 is a novel PPARa agonist that improved aged-induced hepatic steatosis, in part by increasing b-oxidation signaling and decreasing inflammation in the liver. | 28545035 |
| Degenerative polyarthritis, Inflammation, Cartilage damage, glycation | Altered Intercellular Communication | The accumulation of inflammation and cartilage damage induced by advanced glycation end products (AGEs) are important hallmarks of osteoarthritis (OA). | 28545202 |
| Inflammation, Atherosclerosis | Altered Intercellular Communication | Moreover, post-translational modifications such as citrullination and carbamylation have been linked to inflammation and atherosclerosis. | 28545441 |
| Inflammation, Hypoxia | Altered Intercellular Communication | The expression of membrane bound (mb) Tie2 and Ang-1 ensures vessel stability, whereas Ang-2, inducible by vascular endothelial growth factor (VEGF), hypoxia, and inflammation, acts as an antagonist. | 28545512 |
| Sample Size Calculation, Hypoxia | Altered Intercellular Communication | The VEGF tg mouse model, the hypoxia, and the inflammation-dependent bleomycin model all showed a similar dysregulation of Ang/Tie2 as in SSc, which did not apply for the non-inflammatory TSK1 model. | 28545512 |
| Inflammation, Depression, CTCAE | Altered Intercellular Communication | Evidence suggests an association between inflammation and depression, although findings are mixed. | 28546059 |
| Inflammation, Depression, CTCAE, Cognitive | Altered Intercellular Communication | Negative cognitive bias is a key component of depression, but has not been examined in relation to inflammation. | 28546059 |
| Inflammation, Depression, CTCAE | Altered Intercellular Communication | While cross-sectional, results are consistent with research showing that inflammation heightens the salience of negative emotional stimuli, and identify a novel pathway through which inflammation may lead to depression. | 28546059 |
| Exanthema, Arthralgia, Quotidian, Autistic behavior, Juvenile-Onset Still Disease, Myalgia, CTCAE 5 | Altered Intercellular Communication | BACKGROUND Adult Still's disease (ASD) is a rare systemic inflammatory condition, which commonly presents with the triad of quotidian fevers, rash, and non-specific rheumatologic symptoms such as myalgia and arthralgia. | 28546530 |
| Autistic behavior | Altered Intercellular Communication | CONCLUSIONS ASD is a rare systemic inflammatory condition and its nonspecific presentation often leads to diagnostic delay and disease complications. | 28546530 |
| Airway structure, Inflammation, Bronchiectasis | Altered Intercellular Communication | Bronchiectasis is characterized by permanent dilatation of the bronchial tree caused by recurrent airway infection and inflammation. | 28546745 |
| Inflammation, Atherosclerosis | Altered Intercellular Communication | The association of atherosclerosis and inflammation is well established. | 28546745 |
| Inflammation, Uveomeningoencephalitic Syndrome | Altered Intercellular Communication | Early diagnosis and treatment of inflammation are crucial factors in the clinical outcome of Vogt-Koyanagi-Harada disease. | 28548582 |
| Periodontal Diseases, prostatitis | Altered Intercellular Communication | The causal effect of periodontal disease on prostatic inflammation has not been established. | 28548883 |
| Benign prostatic hypertrophy, prostatitis | Altered Intercellular Communication | Chronic prostatitis (CPr) and benign prostatic hyperplasia (BPH) are complex inflammatory conditions for which etiologic determinants are still poorly defined. | 28548883 |
| Nasopharyngeal carcinoma, Acute and chronic inflammation, Malignant Neoplasms | Altered Intercellular Communication | Chronic sinonasal tract inflammation as a precursor to nasopharyngeal carcinoma and sinonasal malignancy in the United States. | 28549211 |
| Inflammation | Altered Intercellular Communication | Impaired monocyte function in MG and decreased expression of genes associated with inflammation resolution could contribute to the chronicity of the disease. | 28549776 |
| Muscle damage, Inflammation, Overweight | Altered Intercellular Communication | Muscle damage derived from overweight displayed by oxidative and endoplasmic reticulum (ER) stress induces inflammation and insulin resistance and forces the muscle to increase requirements from autophagy mechanisms. | 28549989 |
| Inflammation, Neoplasm Metastasis, Trauma, Nervous System | Altered Intercellular Communication | CD44 is an inflammation-related gene encoding a widely-distributed family of alternatively spliced cell surface glycoproteins that have been implicated in inflammation, metastases, and inflammation-linked neuronal injuries. | 28550248 |
| Liver Dysfunction, Overweight, Metabolic Syndrome X | Altered Intercellular Communication | Serum level of chemerin may serve as a measure of ongoing obesity-related inflammation, early marker of subclinical liver dysfunction and metabolic syndrome in overweight pediatric patients. | 28551507 |
| Pituitary Gland, Neoplasms | Altered Intercellular Communication | However, due to concerns of side-effects (radiation-associated tumour, relapse outside the radiation field, mental and pituitary hormonal dysfunction), and after discussing both approaches carefully with the patient, the decision was made to treat his pituitary germinoma with chemotherapy alone. | 28551652 |
| Airway structure, Carcinoma of lung | Altered Intercellular Communication | Acidification of exhaled breath condensate (EBC), reflecting airway inflammation and oxidative stress, has been reported in lung cancer patients undergoing lobectomy. | 28551684 |
| Gastrointestinal inflammation, Colitis | Altered Intercellular Communication | In analyses of intestinal tissues, colitis induction, and gut microbiota in mice with intestinal epithelial disruption of SIRT1, we found this protein to prevent intestinal inflammation by regulating the gut microbiota. | 28552621 |
| Inflammation, Hypertension, CTCAE, atherosclerotic | Altered Intercellular Communication | HIV damages vessel endothelium through chronic inflammation, which, combined with dys-lipidaemia, arterial hypertension, and antiretroviral therapy leads to the progression of atherosclerotic changes. | 28553846 |
| Inflammation, Fibrosis Assessment, Non-alcoholic Fatty Liver Disease, Fatty degeneration | Altered Intercellular Communication | Of the 143 patients with lean NAFLD, 27 had grade 3 steatosis, 24 had a lobular inflammation score greater than 2, 10 had a ballooning score of 2, and 25 had a fibrosis score of 2 or higher. | 28554682 |
| Vasculitis, Transplant glomerulopathy | Altered Intercellular Communication | One hundred fifty-four patients with HLA-DSA-associated severe IF/TA showed significantly increased microvascular inflammation, transplant glomerulopathy, C4d deposition in capillaries, and decreased allograft survival compared to 344 patients with severe IF/TA without HLA-DSAs. | 28554738 |
| Single organ dysfunction, Inflammation, Infections, Hospital, Kidney Failure | Altered Intercellular Communication | Secondary outcomes include main complications of AP (eg, organ failure and mortality, among others), levels of biological markers of systemic inflammation, epithelial lung injury, renal failure, and healthcare-associated costs. | 28554928 |
| Arterial Stiffness, Inflammation, Fibrosis Assessment | Altered Intercellular Communication | It may also cause increased inflammation and fibrosis in the arterial system resulting in an increase in arterial stiffness. | 28554985 |
| Multiple Chronic Conditions, Inflammation, Obesity | Altered Intercellular Communication | Obesity has been related to an increased risk of multiple diseases in which oxidative stress and inflammation play a role. | 28555008 |
| Inflammation, Obesity | Altered Intercellular Communication | Our aim was to analyze the interrelationship among obesity, diet, oxidative stress, inflammation and the intestinal microbiota in 68 healthy adults (29.4% normal-weight). | 28555008 |
| Inflammation, Hyperglycemia, physiopathological | Altered Intercellular Communication | The inflammation and oxidative stress of bone marrow-derived proangiogenic cells (PACs), also named endothelial progenitor cells, triggered by hyperglycemia contributes significantly to vascular dysfunction. | 28555162 |
| Inflammation, Osage language, Hypertensive disease, Sleep Apnea, Obstructive, Hypertension, CTCAE | Altered Intercellular Communication | Obesity-associated systemic hypertension (HTN) and obstructive sleep apnea (OSA) have multiple pathophysiological pathways including ectopic fat deposition, inflammation, altered adipokine profile, and increased sympathetic nervous activity. | 28555408 |
| Communicable Diseases, Inflammation | Altered Intercellular Communication | The aim of this study was to determine the accuracy of LS combined with bone marrow scintigraphy (BMS), as well as inflammation markers CRP and WBC, in detecting infection in patients with prosthetic joints. | 28555449 |
| Inflammation, Juvenile polyposis syndrome | Altered Intercellular Communication | In contrast, however, inflammation markers CRP and WBC are not accurate pre-diagnostic markers for PJI. | 28555449 |
| Bronchial brand of guaifenesin-theophylline, Bronchiectasis, Exacerbation, Chronic Obstructive Airway Disease, Bronchitis, Lung diseases | Altered Intercellular Communication | Bronchiectasis is an incurable pulmonary disorder that is characterized pathologically by permanent bronchial dilatation and severe bronchial inflammation and clinically by chronic productive cough and recurrent infectious exacerbations; bronchiectasis often occurs in the presence of chronic obstructive pulmonary disease. | 28555504 |
| Inflammation, Cholesteatoma, Otosclerosis, Chronic otitis | Altered Intercellular Communication | A statistically significant difference in inflammation score between otosclerosis and chronic otitis samples ( P < 0.01; Anova test) and between otosclerosis and cholesteatoma samples ( P < 0.05; Anova test) was observed; the HMGB1 positivity was in accordance with the density of the inflammatory infiltrate. | 28555513 |
| Inflammation | Altered Intercellular Communication | Although colouterine fistula is usually treated with open surgery, patients with controlled and well-localized inflammation may be good candidates for a laparoscopic approach. | 28557372 |
| Inflammation, Diabetic Retinopathy | Altered Intercellular Communication | Inflammation is known to be involved in the progression of diabetic retinopathy. | 28558009 |
| prostatitis | Altered Intercellular Communication | Inhibition of chronic prostate inflammation by hyaluronic acid through an immortalized human prostate stromal cell line model. | 28558037 |
| prostatitis | Altered Intercellular Communication | These findings suggest that ihPSC could provide a mechanism-based platform for investigating prostate inflammation. | 28558037 |
| ARCN1 gene, Communicable Diseases, Chronic Obstructive Airway Disease, Inflammation | Altered Intercellular Communication | Helicobacter pylori (HP) infection is associated with reduced lung function and systemic inflammation in chronic obstructive pulmonary disease (COPD) patients. | 28558695 |
| palladium, Chronic Kidney Diseases | Altered Intercellular Communication | A malnutrition-inflammation score (MIS) >= 6 occurred in 37 % of PD patients and in 2.5 % of CKD patients. | 28558794 |
| palladium | Altered Intercellular Communication | Apart from age, a condition of malnutrition-inflammation was the major determinant of poor physical activity and capacity in PD patients. | 28558794 |
| Cyst, Hematoma, Neoplasms, Necrosis | Altered Intercellular Communication | These may include inflammations, benign tumors, cysts, hematomas, or, more rarely, focal necrosis. | 28558811 |
| Inflammation, Hypercholesterolemia, Low-Density Lipoproteins, Endometriosis, Hypertension, CTCAE | Altered Intercellular Communication | Conversely, elevated low-density lipoprotein in hypercholesterolemia and chronic systemic inflammation resulting from hypertension may increase the risk of endometriosis. | 28559401 |
| Hypercholesterolemia, Hypertension, CTCAE, Endometriosis | Altered Intercellular Communication | An altered hormonal or chronic systemic inflammatory milieu characterizing endometriosis may result in a higher risk of hypercholesterolemia and hypertension. | 28559401 |
| Aneurysm, Inflammation | Altered Intercellular Communication | In the light of recent reports of the association of wall enhancement with unstable aneurysms, we considered wall enhancement to be a marker of inflammation and remodeling of the aneurysm wall, resulting in chronic hemorrhagic suffusion in the subarachnoid spaces. | 28559509 |
| Inflammation, Hypertension, CTCAE | Altered Intercellular Communication | Studies on the etiology of essential hypertension (EH) have demonstrated that chronic inflammation contributes to the onset and development of elevated blood pressure. | 28560381 |
| Inflammation | Altered Intercellular Communication | Toll-like receptors (TLRs), important immune receptors, serve a role in chronic inflammation and are associated with EH. | 28560381 |
| Inflammation, Trauma, Nervous System, Edema, Neuronal loss in central nervous system, Chronic inflammatory disorder | Altered Intercellular Communication | Connexin43 hemichannels have been called "pathological pores" based upon their role in secondary lesion spread, edema, inflammation, and neuronal loss following central nervous system injuries, as well as in chronic inflammatory disease. | 28560708 |
| Tumor necrosis, Inflammation | Altered Intercellular Communication | Tumour necrosis factor alpha (TNF-a), inducible nitric oxide synthase (iNOS), and cyclooxygenase 2 (COX-2) protein expression indicated that EGCG inhibited ACR-induced inflammation. | 28561817 |
| Corneal Ulcer, Corneal Neovascularization, Corneal edema, Inflammatory abnormality of the eye | Altered Intercellular Communication | Despite temporary discontinuation of erlotinib treatment, the corneal ulcer continued to worsen with peripheral corneal neovascularization, stromal thinning, corneal edema, and profuse inflammation of the ocular surface. | 28562552 |
| Inflammation, Colorectal Carcinoma, Neoplasms | Altered Intercellular Communication | The relationship between tumour stage, systemic inflammation, body composition and survival in patients with colorectal cancer. | 28566220 |
| Peripheral Vascular Diseases, Inflammation | Altered Intercellular Communication | Periodontitis deteriorates peripheral arterial disease in Japanese population via enhanced systemic inflammation. | 28567552 |
| Inflammation, Tooth number | Altered Intercellular Communication | In conclusion, we clarified that PAD patients had decreased tooth number and worsened oral and periodontal condition with enhanced systemic inflammation. | 28567552 |
| Inflammation, Actual blood loss | Altered Intercellular Communication | The 5-dose TXA regimen can further reduce the blood loss, diminish the maximum Hb drop, minimize inflammation, enhance mobility, and shorten LOS following TKA, without increasing the risk of complications. | 28567578 |
| Blood Clot, Endocarditis | Altered Intercellular Communication | Valve inflammation and thrombus formation was mild in majority of the cases. | 28569053 |
| Refractory anemias, Rheumatoid Arthritis, Inflammation | Altered Intercellular Communication | Lipid profiles appear to be altered in rheumatoid arthritis (RA) patients because of disease activity and inflammation. | 28569219 |
| Inflammation, Fibrosis Assessment | Altered Intercellular Communication | Histopathology demonstrated chronic inflammation in the setting of hyalinized fibrosis (7/7). | 28570415 |
| Pain Distress Question, Inflammation, Fatigue | Altered Intercellular Communication | In those reporting severe fatigue (Short-Form 36 vitality <= 12.5), this cross-sectional analysis applied hierarchical clustering with weighted-average linkage identified clusters of pain, fatigue, mental health (all Short-Form 36), disability (Health Assessment Questionnaire), and inflammation (erythrocyte sedimentation rate) in the DMARD cohort. | 28570437 |
| Disability, Inflammation, Pain Distress Question | Altered Intercellular Communication | All clusters had severe levels of pain and disability and were distinguished by the presence/absence of poor mental health and high inflammation. | 28570437 |
| Cerebrovascular Disorders | Altered Intercellular Communication | These results agree with previous observations of the chronic inflammation/prothrombotic tendency in patients with cerebrovascular disease. | 28570705 |
| Orbital Pseudotumor | Altered Intercellular Communication | Consensus on Diagnostic Criteria of Idiopathic Orbital Inflammation Using a Modified Delphi Approach. | 28570731 |
| Primary malignant neoplasm, Orbital Pseudotumor | Altered Intercellular Communication | Current practice to diagnose idiopathic orbital inflammation (IOI) is inconsistent, leading to frequent misdiagnosis of other orbital entities, including cancer. | 28570731 |
| Orbital Pseudotumor | Altered Intercellular Communication | By specifying criteria, diagnosis of orbital inflammation will be improved. | 28570731 |
| Inflammation, Dacryoadenitis, Orbital Pseudotumor, Orbital Myositis | Altered Intercellular Communication | The items were clustered around the anatomic subtypes of IOI: idiopathic dacryoadenitis and idiopathic orbital fat inflammation (2 nonmyositic IOIs), and idiopathic orbital myositis (myositic IOI). | 28570731 |
| Gastroesophageal reflux disease, Inflammation | Altered Intercellular Communication | Given that OAC stems from acid reflux and that the oesophageal epithelium undergoes a metaplasia-dysplasia transition from the resulting inflammation, it is plausible that a high DII score (indicating a pro-inflammatory diet) may exacerbate risk of OAC and its precursor conditions. | 28571591 |
| Esophageal carcinoma | Altered Intercellular Communication | In conclusion, a pro-inflammatory diet may exacerbate the risk of the inflammation-metaplasia-adenocarcinoma pathway in oesophageal carcinogenesis. | 28571591 |
| Constriction procedure, Myocarditis | Altered Intercellular Communication | Cardiac magnetic resonance imaging confirmed a globally thickened pericardium and showed evidence of pericardial inflammation and constrictive physiology. | 28572226 |
| Degenerative polyarthritis, Inflammation | Altered Intercellular Communication | Recent studies suggest the role of inflammation in the pathogenesis of OA. | 28573383 |
| Inflammation, Degenerative disorder of cartilage | Altered Intercellular Communication | The knee joint experiences more mechanical stress, cartilage degeneration, and inflammation than the hip joint. | 28573383 |
| Inflammation | Altered Intercellular Communication | This facilitates increased cartilage degradation and inflammation in the joint. | 28573383 |
| Inflammation, melanoma | Altered Intercellular Communication | Nucleated cells in the dermis and the RCM correlate of dermal inflammation were also significant RCM features favouring DM over MIS, as well as invasive melanoma over MIS. | 28573666 |
| Tears body substance, Inflammation, Macular Edema, Cystoid | Altered Intercellular Communication | Main complications observed were prolonged postoperative inflammation in 25% (n = 31), posterior capsular tears in 0.45% (n = 11), and unilateral cystoid macular edema in 0.08% (n = 2) eyes. | 28573990 |
| Cataract, Inflammation | Altered Intercellular Communication | After inflammation control, complicated cataract was managed surgically under perioperative steroid cover. | 28574002 |
| Inflammation, Acquired Immunodeficiency Syndrome, Uveomeningoencephalitic Syndrome | Altered Intercellular Communication | This case shows that significant inflammation can be seen even in HIV/AIDS patients on HAART with VKH in spite of moderate CD4 counts. | 28574002 |
| Inflammation, cardiac muscle tissue growth | Altered Intercellular Communication | mRNA transcripts involved in activation of satellite cells, myogenesis, regeneration, adipogenesis, muscle growth and tissue inflammation were assessed. | 28574407 |
| Inflammation, melanoma | Altered Intercellular Communication | Growing evidence indicates that inflammation plays a critical role in the development and progression of acral melanoma. | 28574975 |
| Tumor necrosis, Primary malignant neoplasm, Inflammation | Altered Intercellular Communication | Tumor necrosis factor-a (TNF-a), an important factor in systematic inflammation, is reportedly involved in several cancer types. | 28575042 |
| Inflammation, Obesity | Altered Intercellular Communication | Impacts of chronic systemic inflammation and body size and their interaction effect on insulin resistance in Asian populations, in whom obesity is less common, are not fully understood. | 28575103 |
| Inflammation, Obesity | Altered Intercellular Communication | Concomitant obesity and elevated systemic inflammation may synergistically contribute to increased insulin resistance. | 28575103 |
| Inflammation, Impaired cognition, "Alzheimers Disease | Altered Intercellular Communication | Brain inflammation accompanies amyloid in the majority of mild cognitive impairment cases due to Alzheimer's disease. | 28575151 |
| Inflammation, Impaired cognition | Altered Intercellular Communication | 11C-(R)-PK11195 positron emission tomography reveals increased inflammation in a majority of amyloid positive mild cognitive impairment cases, its cortical distribution overlapping that of amyloid deposition. | 28575151 |
| Granuloma, Inflammation, Caseous necrosis | Altered Intercellular Communication | Tissue acquisition revealed epithelioid granuloma in 33 patients, caseous necrosis in 13, a positive AFB stain in 14, and nonspecific chronic inflammation in 2. | 28575247 |
| Inflammation | Altered Intercellular Communication | The remaining two with only nonspecific chronic inflammation received empirical antitubercular chemotherapy based solely on EUS morphology. | 28575247 |
| Inflammation, Endophthalmitis, CTCAE | Altered Intercellular Communication | Exogenous endophthalmitis is an ophthalmologic emergency defined by panocular inflammation. | 28576209 |
| Inflammation | Altered Intercellular Communication | Vascular endothelial growth factor A (VEGF-A) contributes to inflammation by promoting chemotaxis of monocytes and granulocytes and by increasing vascular permeability. | 28576209 |
| Malignant tumor of colon, Dysbiosis | Altered Intercellular Communication | Thus, pig model can aid in the development of preventive strategies against gut bacterial dysbiosis and inflammation-promoted diseases, such as colon cancer. | 28576788 |
| Inflammation, Mycobacterium Infections | Altered Intercellular Communication | He underwent renal biopsy that revealed necrotizing granulomatous inflammation suggestive of mycobacterial infection. | 28577928 |
| Fracture | Altered Intercellular Communication | Endogenous parathyroid hormone (PTH) plays an important role in fracture healing. | 28578352 |
| Malignant neoplasm of urinary bladder | Altered Intercellular Communication | To explore the prognostic significance of preoperative prognostic nutritional index (PNI) in bladder cancer after radical cystectomy and compare the prognostic ability of inflammation-based indices. | 28578683 |
| Inflammation, Fibrosis Assessment, Hepatitis C | Altered Intercellular Communication | Interferon-gamma (IFN-g)-inducible protein-10 (IP-10), soluble (s) CD163 and sCD14 play an important role in the pathogenesis of HCV and HIV infection and are involved in inflammation and liver fibrosis. | 28578937 |
| Atrial Fibrillation by ECG Finding | Altered Intercellular Communication | Association of Systemic Inflammation Score With Atrial Fibrillation: A Case-Control Study With Propensity Score Matching. | 28579228 |
| Inflammation, Atrial Fibrillation by ECG Finding | Altered Intercellular Communication | Inflammation plays a key role in the initiation and progression of atrial fibrillation (AF). | 28579228 |
| Inflammation, Pythiosis, Destruction (action) | Altered Intercellular Communication | Corneal pythiosis showed epithelial ulceration, stromal destruction, and varying inflammation; load and distribution of Pythium were inversely proportional to inflammation. | 28582375 |
| Inflammation, Diabetic peripheral neuropathy, Diabetes Mellitus, Non-Insulin-Dependent | Altered Intercellular Communication | Diabetic peripheral neuropathy (DPN) had been demonstrated as a chronic inflammation state and one of the most common complications of type 2 diabetes mellitus (T2DM). | 28582723 |
| Inflammatory disorder, Diabetes Mellitus | Altered Intercellular Communication | Neutrophil-to-lymphocyte ratio (NLR) is a novel marker to reflect many kinds of chronic inflammation disease including diabetes. | 28582723 |
| Inflammation, Dementia | Altered Intercellular Communication | Alterations in the immune response that result in inflammation might play a role in the pathology of dementias. | 28582858 |
| Inflammation | Altered Intercellular Communication | The inflammation was successfully resolved, and the implant was removed through a minimally invasive endoscopic sinus surgery technique. | 28582957 |
| Inflammation, Primary malignant neoplasm, Colorectal Carcinoma | Altered Intercellular Communication | Inflammation is widely recognized to play an important role in cancer progression, and the peripheral monocyte count has been reported to correlate with the prognosis in patients with colorectal cancer. | 28583114 |
| Atrophy of prostate, Inflammation, Prostate carcinoma | Altered Intercellular Communication | The combination of histological prostate atrophy and inflammation is associated with lower risk of prostate cancer in biopsy specimens. | 28585572 |
| Atrophy of prostate, Prostate carcinoma, prostatitis, Structure of posterior cerebral artery | Altered Intercellular Communication | To evaluate whether the presence of both prostate atrophy (PA) and chronic prostate inflammation (CPI) in the same biopsy and in the same biopsy core are associated with prostate cancer (PCa) risk and grade in repeat biopsies. | 28585572 |
| Gastrointestinal inflammation | Altered Intercellular Communication | These data suggest that IL-17A+ IFN-g+ and IL-22+ IFN-g+ T cell subsets might represent the pathogenic T helper type 17 (Th17) population in the context of intestinal inflammation for CD patients. | 28586085 |
| Crohn Disease | Altered Intercellular Communication | Crohn's disease (CD) is a chronic inflammatory condition of the human gastrointestinal tract whose aetiology remains largely unknown. | 28586085 |
| Inflammation, Hypertensive (finding), metabolic disturbance | Altered Intercellular Communication | Salsalate ameliorates metabolic disturbances by reducing inflammation in spontaneously hypertensive rats expressing human C-reactive protein and by activating brown adipose tissue in nontransgenic controls. | 28586387 |
| Inflammation | Altered Intercellular Communication | Chronic low-grade inflammation plays an important role in the pathogenesis of insulin resistance. | 28586387 |
| Dermatitis, Necrotizing fasciitis | Altered Intercellular Communication | Necrotizing fasciitis (NF) is a serious and potentially fatal condition where there is rapid progression of inflammation of skin, subcutaneous tissue, and superficial fascia and can be mono-microbial or poly-microbial. | 28586594 |
| Inflammation, Chronic multifocal osteomyelitis | Altered Intercellular Communication | Histopathology demonstrated only non-specific chronic inflammation compatible with CRMO. | 28587611 |
| Inflammation | Altered Intercellular Communication | Furthermore, inflammation plays an important role in the pathogenesis of BC. | 28587816 |
| Inflammation, Obesity | Altered Intercellular Communication | Obesity is associated with chronic, low grade, systemic inflammation. | 28588155 |
| Inflammation, Fibrosis Assessment, Asbestosis | Altered Intercellular Communication | We studied if YKL-40 is related to inflammation, fibrosis, and/or lung function in subjects exposed to asbestosis. | 28588347 |
| Inflammation, Fibrosis Assessment | Altered Intercellular Communication | The present finding suggests YKL-40 as a biomarker associated with fibrosis and inflammation in asbestos-exposed subjects. | 28588347 |
| Inflammation | Altered Intercellular Communication | These findings suggest that higher SFA and minor n-6 HUFA, namely PA and AA, are associated with increased low-grade inflammation in children, whereas the major dietary n-6 PUFA and total PUFA are associated with reduced inflammation. | 28589948 |
| Inflammation | Altered Intercellular Communication | Elevated desaturase activity, estimated by the ratio AA/LA, may be associated with higher inflammation, particularly in boys. | 28589948 |
| Peripheral retinoschisis, Peripheral Ischemia, Vitreous inflammatory cells, Uveitis | Altered Intercellular Communication | The appearance of peripheral retinoschisis in this series of uncontrolled intermediate uveitis patients seems to be secondary to a complex balance between the persistent fluorescein leakage, a subclinical peripheral ischemia, and the constant low-grade vitreous inflammation that causes vitreous shrinkage and traction. | 28590967 |
| Inflammation | Altered Intercellular Communication | Good preoperative and postoperative control of inflammation plays an important role in achieving favorable visual outcomes. | 28591283 |
| Inflammation, Chronic Kidney Diseases | Altered Intercellular Communication | In conclusion, elevated WBC count served as a predictor of the odds of kidney function decline in this population, which supports the hypothesis that systemic inflammation may serve as a risk factor for CKD development. | 28592280 |
| Toxic effect, Hypokalemia, Asthenia, DLST wt Allele, Dermatitis acneiform | Altered Intercellular Communication | Dose-limiting toxicities (DLTs) included grade 4 hypokalemia and grade 3 mucosal inflammation, asthenia, and dermatitis acneiform. | 28592615 |
| Inflammation, Native Valve Endocarditis, Heart failure | Altered Intercellular Communication | Patients with a perivalvular abscess had a greater number ofStaphylococcusspecies and prosthetic valve endocarditis, a greater level of inflammation at diagnosis and symptomatic heart failure before surgery, especially in the ARR group. | 28592753 |
| Inflammation, Cystitis, Pneumonia, Leukemia, Myelomonocytic, Chronic, Inflammatory disorder of cartilage | Altered Intercellular Communication | Here, we describe the occurrence of eosinophil-rich tissue inflammation, including eosinophilic pneumonia, chondritis, and cystitis, in CMML patients. | 28593791 |
| hearing impairment, Inflammation, Ear Inflammation | Altered Intercellular Communication | Association of Gel-Forming Mucins and Aquaporin Gene Expression With Hearing Loss, Effusion Viscosity, and Inflammation in Otitis Media With Effusion. | 28594978 |
| hearing impairment, Inflammation, Otitis Media with Effusion | Altered Intercellular Communication | To investigate the association of gel-forming mucins and aquaporin 5 (AQP5) gene expression with inflammation, effusion viscosity, and hearing loss in pediatric OM with effusion (OME). | 28594978 |
| Inflammation | Altered Intercellular Communication | Recent evidence indicates that a systemic state of inflammation may impair fertility, but data about psoriatic males are scarce. | 28595175 |
| Inflammation, Psoriasis | Altered Intercellular Communication | Ultrasound signs of inflammation of the accessory glands were observed in 35/50 patients with psoriasis and in none of the controls. | 28595175 |
| Inflammation | Altered Intercellular Communication | We also found that this might be due to an impact of systemic inflammation on the hormonal profile and on sexual accessory gland inflammation. | 28595175 |
| Inflammation | Altered Intercellular Communication | We also found that this might be due to an impact of systemic inflammation on the hormonal profile and on sexual accessory gland inflammation. | 28595175 |
| Parkinson Disease, Inflammation | Altered Intercellular Communication | White matter damage and systemic inflammation in Parkinson's disease. | 28595572 |
| Parkinson Disease, Inflammation, palladium, Leukoaraiosis | Altered Intercellular Communication | Systemic inflammation and white matter (WM) alterations have been noted as effects of Parkinson's disease (PD). | 28595572 |
| palladium, Inflammation | Altered Intercellular Communication | Patients with PD experience WM integrity damage in vulnerable regions, and these impairments are associated with increased disease severity and systemic inflammation. | 28595572 |
| ARCN1 gene, Inflammation, Chronic Obstructive Airway Disease, Non-alcoholic Fatty Liver Disease, Liver damage | Altered Intercellular Communication | Low-grade inflammation, oxidative stress and ectopic fat, common features of chronic obstructive pulmonary disease (COPD), might contribute to the development of NAFLD.We aimed to investigate the prevalence of NAFLD and to evaluate the relationship between various types of liver damage and COPD severity, comorbidities and circulating inflammatory cytokines. | 28596431 |
| Moyamoya Disease, MMD gene | Altered Intercellular Communication | Immuno-inflammation has been shown to play a pivotal role in the pathogenesis of moyamoya disease (MMD). | 28596558 |
| Inflammation | Altered Intercellular Communication | The pathological diagnosis showed only chronic inflammation in their medical records. | 28596692 |
| Inflammation, Fibrosis Assessment, Heart failure | Altered Intercellular Communication | Objective We performed a prospective observational study to explore the prognostic value of plasma galectin-3, a biomarker for fibrosis and inflammation, in Chinese patients with heart failure (HF). | 28597803 |
| Aneurysm, Endothelium, Inflammation | Altered Intercellular Communication | These predictors of multiple aneurysms likely reflect a predisposition toward inflammation and endothelial injury. | 28598275 |
| Refractory anemias, Rheumatoid Arthritis, Arthritis, Infiltration | Altered Intercellular Communication | Rheumatoid arthritis (RA) is characterized by chronic joint inflammation and infiltration by activated macrophages. | 28598681 |
| Communicable Diseases, Inflammation, Pain Distress Question | Altered Intercellular Communication | We evaluated: wound healing time, pain severity and duration, the frequency of dressing change, donor site re-epithelialisation, donor site complications (signs of inflammation or infection). | 28598760 |
| Inflammation, Fibrosis Assessment | Altered Intercellular Communication | Additionally, 110 (37.2%) had clinically significant (stage 2+) fibrosis and 256 (86.5%) had portal inflammation. | 28600116 |
| Inflammation, Fibrosis Assessment, Fatty Liver Disease | Altered Intercellular Communication | CCRL2 mRNA levels were positively correlated with inflammation, fibrosis and NASH scores in the patients. | 28600126 |
| Inflammation | Altered Intercellular Communication | These indicated ongoing inflammation, bone formation and increased fibroblasts activity in the FJ bone. | 28600230 |
| Inflammatory disorder | Altered Intercellular Communication | Asthma is an inflammatory disease and interleukin 12 (IL-12) may play a regulatory role in allergen-induced inflammation. | 28600552 |
| Inflammation | Altered Intercellular Communication | Chronic inflammation in AC might be associated with late onset complications. | 28600745 |
| Inflammation, Destruction of tissue | Altered Intercellular Communication | Oxidative stress as a consequence of immune cell activation and disease-modifying anti-rheumatic drugs can prevent inflammation and tissue destruction. | 28601049 |
| Colorectal Carcinoma | Altered Intercellular Communication | The cohort consisted of newly diagnosed CRC adult patients during 2003-2010 with at least one prescription of nonsteroidal anti-inflammation drugs. | 28601236 |
| Inflammation, Bone necrosis | Altered Intercellular Communication | The effect of chronic dental inflammation on development of Stage 0 medication-related osteonecrosis of the jaw. | 28601298 |
| Inflammation | Altered Intercellular Communication | Chronic inflammation may contribute to Stage 0 MRONJ; however, its role may not be sufficient alone for its development. | 28601298 |
| Inflammation, Crohn Disease | Altered Intercellular Communication | Correlation between fecal calprotectin and inflammation in the surgical specimen of Crohn's disease. | 28601328 |
| Inflammation, Fibrosis Assessment | Altered Intercellular Communication | Chiorean's score was used to grade pathologic features (inflammation or fibrosis). | 28601328 |
| Inflammation | Altered Intercellular Communication | Among inflammatory markers, only FC was significantly associated with the degree of histologic inflammation in the surgical specimen (P < 0.003). | 28601328 |
| Inflammation | Altered Intercellular Communication | Ordinal regression analysis showed the probability of a greater or lesser degree of inflammation based on the value of preoperative FC. | 28601328 |
| Inflammation, Intestines, Small | Altered Intercellular Communication | FC is an excellent biomarker of inflammatory activity in small bowel CD as it correlates with histologic inflammation in the surgical specimen. | 28601328 |
| Squamous cell carcinoma of esophagus | Altered Intercellular Communication | A novel systemic immune-inflammation index predicts survival and quality of life of patients after curative resection for esophageal squamous cell carcinoma. | 28601935 |
| Neoplasms | Altered Intercellular Communication | A novel systemic immune-inflammation index (SII) based on platelet (P), neutrophil (N), and lymphocyte (L) counts has been reported to be associated with clinical outcomes in several solid tumors. | 28601935 |
| Intrahepatic Cholangiocarcinoma | Altered Intercellular Communication | Various inflammation-based prognostic biomarkers such as the platelet to lymphocyte ratio and neutrophil to lymphocyte ratio, are related to poor survival in patients with intrahepatic cholangiocarcinoma (ICC). | 28602056 |
| Inflammation, Fibrosis Assessment | Altered Intercellular Communication | Mdr2-/- mice provide a reliable in vivo model of PSC and develop characteristic biliary inflammation and fibrosis. | 28602220 |
| Inflammation, Colon diverticulum anatomic structure | Altered Intercellular Communication | Colonic Diverticula Are Not Associated With Mucosal Inflammation or Chronic Gastrointestinal Symptoms. | 28603053 |
| Diverticular disease of colon | Altered Intercellular Communication | Colonic diverticulosis has been reported to be associated with low-grade mucosal inflammation, possibly leading to chronic gastrointestinal symptoms. | 28603053 |
| Inflammation, HAMA - Gastrointestinal Symptoms, Diverticulum | Altered Intercellular Communication | We aimed to determine mucosal inflammation and whether diverticula are associated with chronic gastrointestinal symptoms. | 28603053 |
| Inflammation, Diverticulum | Altered Intercellular Communication | We explored whether inflammation was present among symptomatic participants with and without diverticula. | 28603053 |
| Inflammation, Diverticulosis | Altered Intercellular Communication | There was no evidence for inflammation in patients with symptoms when patients with vs without diverticulosis were compared. | 28603053 |
| Diverticular disease of colon, Gastrointestinal symptom, Inflammatory disease of mucous membrane | Altered Intercellular Communication | We found no evidence that colonic diverticulosis is associated with mucosal inflammation or gastrointestinal symptoms. | 28603053 |
| Inflammation, Diverticulum | Altered Intercellular Communication | Among patients with symptoms and diverticula, we found no mucosal inflammation. | 28603053 |
| Cows milk", Inflammation | Altered Intercellular Communication | After food reintroduction, the most common food triggers that induced histologic inflammation were cow's milk (85%), egg (35%), wheat (33%), and soy (19%). | 28603055 |
| Esophagitis, "Extra-osseous Ewings sarcoma | Altered Intercellular Communication | One food trigger that induced recurrence of esophageal inflammation was identified in 62% of patients and cow's milk-induced EoE was present in 88% of these patients. | 28603055 |
| Inflammation, Primary malignant neoplasm, Colorectal Carcinoma | Altered Intercellular Communication | STAT3 signaling pathway is regarded as the "bridge" between inflammation and cancer, and involved in the development of CRC. | 28603075 |
| Hairy Cell Leukemia, Inflammation | Altered Intercellular Communication | CD11c, expressed not only in Hairy cell leukemia but also in dendritic cells, macrophages and monocytes is a differentiation marker for inflammation. | 28603911 |
| Autoimmune Diseases, Inflammation, Chronic Lymphocytic Leukemia, Neoplasms | Altered Intercellular Communication | Prolonged inflammation in the microenvironment of CLL cells may cause a susceptibility to autoimmune disorders and secondary tumors in CLL, in this way, an increase in mortality. | 28603911 |
| Inflammation, Arthritis | Altered Intercellular Communication | In the current study, we tested whether the association between well-being and inflammation results in a lower risk of arthritis. | 28604559 |
| Osteoporosis | Altered Intercellular Communication | However, the incidence and risk of osteoporosis after acute inflammation of pancreas remained known. | 28604838 |
| Inflammation, Nerve injury, Gout | Altered Intercellular Communication | Our clinical case is another example of how gout can produce spinal inflammation and nerve damage and superimpose on previously damaged joints and how patients' compliance to therapeutics may have an important impact on prognosis. | 28605749 |
| Inflammation | Altered Intercellular Communication | We conclude that altered levels of OEA and PEA might indicate the presence of systemic inflammation in CWP. | 28606089 |
| Pneumonitis | Altered Intercellular Communication | This outperforming of the weighted GRS was confirmed in a real data application on lung inflammation in the SALIA cohort (n = 402). | 28606108 |
| Inflammation, Traumatic injury | Altered Intercellular Communication | Heightened local inflammation due to muscle trauma or disease is associated with impaired bone regeneration. | 28606129 |
| Inflammatory Bowel Diseases, CDISC Integrated Basic Data Structure Dataset, Gastrointestinal inflammation | Altered Intercellular Communication | An increasing number of physicians use repeated measurements of stool calprotectin to monitor intestinal inflammation in patients with inflammatory bowel diseases (IBDs). | 28606846 |
| Inflammation, Cardiovascular Diseases, Refractory anemias, Cyclophosphamide/Vincristine/Dacarbazine Regimen, Rheumatoid Arthritis | Altered Intercellular Communication | Systemic inflammation appears to contribute to the excess risk of cardiovascular disease (CVD) in rheumatoid arthritis (RA). | 28606965 |
| Inflammation, CHOP regimen, Arthritis, Psoriatic | Altered Intercellular Communication | The dynamics of response as measured by multiple composite outcome tools in the TIght COntrol of inflammation in early Psoriatic Arthritis (TICOPA) trial. | 28606970 |
| Inflammation, neuron death | Altered Intercellular Communication | Targets of these microRNAs include proteins regulating neuronal death, tissue remodelling, gliosis and inflammation. | 28607431 |
| Inflammation | Altered Intercellular Communication | Oxidative stress is one of the major causes of inflammation in NAFLD/NASH. | 28608557 |
| allergic inflammation, Illness (finding) | Altered Intercellular Communication | Allergic inflammation has been linked to increased susceptibility to viral illnesses, but it is unclear whether this association is causal. | 28608756 |
| glycation, Inflammation | Altered Intercellular Communication | Receptor for advanced glycation end products (RAGE) and its cleavage fragment soluble RAGE (sRAGE) are opposite players in inflammation. | 28608784 |
| Inflammation, Shock, Cardiogenic | Altered Intercellular Communication | Maintaining MMP-9 activity could be a therapeutic target to limit RAGE-induced deleterious inflammation in cardiogenic shock. | 28608784 |
| Malignant - descriptor, Granulomatous inflammation | Altered Intercellular Communication | Among PET-positive LNs, 41.9% were malignant, 41.9% showed reactive changes or granulomatous inflammation, and 9.3% were nondiagnostic by EBUS-TBNA. | 28609021 |
| Inflammation, Diabetes Mellitus, Non-Insulin-Dependent | Altered Intercellular Communication | The 12-lipoxygenase (12-LO) pathway produces proinflammatory metabolites, and its activation is implicated in islet inflammation associated with type 1 and type 2 diabetes (T2D). | 28609824 |
| Tumor necrosis, Inflammation | Altered Intercellular Communication | Human islets from nondiabetic donors were incubated with a mixture of tumor necrosis factor a , interluekin-1b, and interferon-g to model islet inflammation. | 28609824 |
| Orbital Pseudotumor | Altered Intercellular Communication | Patients observed due to idiopathic inflammation of the mesentery were identified. | 28610559 |
| Inflammation, Fever, CTCAE | Altered Intercellular Communication | All four had marked systemic inflammation, fever and fluctuating radiologic findings. | 28610559 |
| Idiopathic Inflammatory Myopathies, Retractile Mesenteritis | Altered Intercellular Communication | Sclerosing mesenteritis (SM) is sometimes used as an umbrella-term for idiopathic inflammatory conditions in the mesentery. | 28610559 |
| Inflammation | Altered Intercellular Communication | increased production of IL-1b or IL-6), whereas it blunted inflammatory mediators in macrophages and consequently chronic inflammation. | 28610607 |
| Inflammation, Dyslipidemias, Diabetes Mellitus, Heart Diseases, Obesity | Altered Intercellular Communication | Close cardiac screening and aggressive modification of other manifestations of AS that are risk factors for cardiac disease, including obesity, inflammation, diabetes and dyslipidemia, are essential in caring for patients with AS. | 28610912 |
| Inflammation, Rheumatoid Arthritis, Pain Distress Question | Altered Intercellular Communication | Magnetic resonance imaging assessed inflammation in the wrist is associated with patient-reported physical impairment, global assessment of disease activity and pain in early rheumatoid arthritis: longitudinal results from two randomised controlled trials. | 28611080 |
| Refractory anemias, Inflammation, Rheumatoid Arthritis | Altered Intercellular Communication | To examine whether MRI assessed inflammation and damage in the wrist of patients with early rheumatoid arthritis (RA) are associated with patient-reported outcomes (PROs). | 28611080 |
| Inflammation | Altered Intercellular Communication | MRI inflammation, but not damage, showed statistically significant associations with HAQ, VAS-PtGlobal and VAS-pain for status and change scores, independently of C reactive protein and swollen joint count. | 28611080 |
| Refractory anemias, Inflammation, Pain Distress Question | Altered Intercellular Communication | MRI-assessed inflammation, but not damage, in early RA wrists is associated with patient-reported physical impairment, global assessment of disease activity and pain and influences the physical function in the hand. | 28611080 |
| Inflammation, Fibrosis Assessment, Fatty degeneration | Altered Intercellular Communication | With metformin, weighted liver histologic scores for steatosis, ballooning, and fibrosis did not demonstrate significant improvement and lobular inflammation worsened significantly (weighted mean increase 0.21, 95% CI 0.11 to 0.31, P < 0.0001). | 28611274 |
| Inflammation, Fatty degeneration | Altered Intercellular Communication | The liver histology score including steatosis (OR 3.51, 95% CI 2.14 to 5.78) and lobular inflammation (OR 2.65, 95% CI 1.69 to 4.15) improved with TZDs. | 28611274 |
| Inflammation, Fatty degeneration | Altered Intercellular Communication | With Vitamin E, weighted liver histologic scores for steatosis (weighted mean decrease -0.60, 95% CI -0.85 to -0.35, P < 0.0001), lobular inflammation (weighted mean decrease - 0.40, 95% CI -0.61 to -0.20, P = 0.0001) and ballooning (weighted mean decrease -0.30, 95% CI -0.54 to -0.07, P = 0.01) demonstrated significant improvement compared to placebo. | 28611274 |
| Inflammation, Dental Plaque | Altered Intercellular Communication | Comparative evaluation of Mangifera indica leaf mouthwash with chlorhexidine on plaque accumulation, gingival inflammation, and salivary streptococcal growth. | 28611324 |
| Inflammation, Bulla | Altered Intercellular Communication | While cytokines are crucial for the affinity and activation of different leukocyte cells in the inflammation and blister formation, there are no studies concerning a role of IL-36. | 28611508 |
| Hidradenitis Suppurativa | Altered Intercellular Communication | Hidradenitis suppurativa is a painful and disfiguring chronic inflammatory condition affecting both men and women. | 28612149 |
| Inflammation, Fatty degeneration | Altered Intercellular Communication | In an ordinal logistic regression, significant risk factors for steatosis were female gender (OR 1.5, P = 0.034) and inflammation grade (P = 0.001). | 28612194 |
| Adenoma, Basal Cell, Malignant Neoplasms | Altered Intercellular Communication | The analysed material included 27 MA, 26 PA, 1 basal cell adenoma, 8 inflammatory conditions, and 10 malignant neoplasms. | 28612315 |
| Inflammation | Altered Intercellular Communication | Further, moderate drinkers had lower CRP levels suggesting that inflammation partially mediates the relationship between moderate alcohol use and depressive symptomatology. | 28612359 |
| Waldenstrom Macroglobulinemia, Fibrosis Assessment, Mass in breast | Altered Intercellular Communication | Histologic examination showed fibrosis and dense lymphoplasmacytic inflammation in the breast mass and muscle biopsy. | 28612666 |
| Inflammatory Bowel Diseases, Crohn Disease, Inflammation, Ulcerative Colitis | Altered Intercellular Communication | In the two inflammatory bowel diseases, ulcerative colitis (UC) and Crohn's disease (CD), altered expression of tight junction (TJ) proteins leads to an impaired epithelial barrier including increased uptake of luminal antigens supporting the inflammation. | 28612843 |
| Inflammation, Heart failure | Altered Intercellular Communication | Growth differentiation factor-15 (GDF-15), a biomarker associated with remodeling, oxidative stress and inflammation, has been used to stratify heart failure (HF) patients. | 28612904 |
| Coin lesion of lung | Altered Intercellular Communication | It is not known whether IgG4-RD can be diagnosed on the basis of pulmonary lesions only, because increases in serum IgG4 levels and infiltration of IgG4-positive plasma cells into the lung tissue also occur in other inflammatory conditions. | 28614225 |
| Inflammation, Abnormality of the vasculature, Chronic Kidney Diseases | Altered Intercellular Communication | IL-33 and ST2 levels in chronic kidney disease: Associations with inflammation, vascular abnormalities, cardiovascular events, and survival. | 28614418 |
| Vascular System Injuries, Inflammation, Chronic Kidney Diseases, Cardiovascular Diseases | Altered Intercellular Communication | Increased inflammation, associated with the increase in chronic kidney disease (CKD) stage, has a very important influence in vascular injury and cardiovascular diseases. | 28614418 |
| Communicable Diseases, Cirrhotic, Inflammation, Bacterial Infections | Altered Intercellular Communication | However, there have been no studies of the trends in endocan levels in cirrhotic patients with bacterial infection and their associations with markers of infection and inflammation. | 28614777 |
| Communicable Diseases, Inflammation, Liver Cirrhosis | Altered Intercellular Communication | We analyzed the association of endocan with clinical factors in cirrhosis by comparison with indicators of infection and inflammation. | 28614777 |
| Communicable Diseases, Malignant Neoplasms, Rheumatism | Altered Intercellular Communication | Infection was the most prevalent cause (55.1%), followed by rheumatologic diseases (7.5%), multiple causes (5.6%), other inflammatory conditions (5.4%), malignancy (5.1%), drug reactions (1.7%), and other conditions (2.0%). | 28615410 |
| Degenerative polyarthritis, Inflammation | Altered Intercellular Communication | Increasing evidence suggests that inflammation plays a central role in driving joint pathology in certain patients with osteoarthritis (OA). | 28615667 |
| Degenerative polyarthritis, Inflammation | Altered Intercellular Communication | Since many patients with OA are obese and increased adiposity is associated with chronic inflammation, we investigated whether obese patients with hip OA exhibited differential pro-inflammatory cytokine signalling and peripheral and local lymphocyte populations, compared to normal weight hip OA patients. | 28615667 |
| Airway structure, ARCN1 gene | Altered Intercellular Communication | Systemic and airway inflammation play roles in the pathogenesis of COPD exacerbation. | 28615935 |
| Inflammation, Erdheim-Chester Disease, Histiocytosis, Non-Langerhans-Cell, Traumatic injury | Altered Intercellular Communication | Erdheim-Chester Disease (ECD) is a rare type of non-Langerhans cell histiocytosis characterized by tissue inflammation and injury caused by macrophage infiltration and histologic findings of foamy histiocytes. | 28617889 |
| Histiocytosis, Non-Langerhans-Cell, Gastrointestinal inflammation | Altered Intercellular Communication | Non-Langerhans histiocytosis and ECD are rare causes of gastrointestinal inflammation. | 28617889 |
| Electrocardiogram: myocardial infarction (finding) | Altered Intercellular Communication | We aimed to assess whether the inflammation-related microRNA-155 is associated with the development of adverse left ventricular (LV) remodeling following ST elevation myocardial infarction (STEMI). | 28618412 |
| Inflammation, Transcription Initiation | Altered Intercellular Communication | Inflammation is strongly associated with cancer initiation, and the role of LDL in intestinal tumorigenicity should be further explored. | 28618417 |
| Inflammation, Primary malignant neoplasm | Altered Intercellular Communication | Inflammation is a new hallmark feature of cancer initiation and progression. | 28618954 |
| Inflammation, Renal Cell Carcinoma Pathway | Altered Intercellular Communication | Time-dependent effects of prognostic biomarkers of systemic inflammation in patients with metastatic renal cell carcinoma. | 28618965 |
| Terminal illness, Inflammation | Altered Intercellular Communication | Terminal disease progression with severe systemic inflammation was detected in 87% of the 90 patients who died. | 28618965 |
| Inflammation, Humor, Periphlebitis | Altered Intercellular Communication | Anterior inflammation and periphlebitis gradually improved and VZV-DNA in the aqueous humor was reduced to 1.02 x 106 copies/mL at 4 weeks after presentation. | 28619012 |
| Inflammation, Humor | Altered Intercellular Communication | Examination by slit lamp microscope revealed no inflammation after 5 months, and VZV-DNA could no longer be detected in the aqueous humor. | 28619012 |
| Inflammatory abnormality of the eye | Altered Intercellular Communication | Serum anti-VZV IgG and anti-VZV IgM also showed a gradual decrease along with improvement in ocular inflammation. | 28619012 |
| Inflammatory abnormality of the eye, Hyphema, Humor, Uveitis | Altered Intercellular Communication | VZV-associated uveitis may develop hyphema that obscures ocular inflammation, thus PCR analysis using the aqueous humor is the key investigation necessary for the diagnosis. | 28619012 |
| Have Autoimmune or Inflammatory Condition | Altered Intercellular Communication | Autoimmune inflammation is common in the early stages of MS and is followed by neurodegenerative processes. | 28619424 |
| PROS1 gene, Arthritis | Altered Intercellular Communication | In patients with PsA, poor sleep is associated with active joint inflammation. | 28620064 |
| Inflammation | Altered Intercellular Communication | We identified differences in expression of mucin genes, cytokeratin-14 and molecular markers of inflammation. | 28620964 |
| Sarcoidosis | Altered Intercellular Communication | Pediatric sarcoidosis comprises a spectrum of childhood granulomatous inflammatory conditions. | 28621099 |
| Inflammation | Altered Intercellular Communication | To report a case of severe anterior segment inflammation secondary to exposure to a high-power blue laser device. | 28622043 |
| Inflammation, Biliary calculi, Mucous Membrane, Lobular Endocervical Glandular Hyperplasia, Intestinal metaplasia | Altered Intercellular Communication | Despite paucity of inflammation and gallstones, findings attributed to mucosal injury were common including: pyloric gland metaplasia (70% vs. 48%, P=0.01) and intestinal metaplasia (24% vs. 6%, P<0.01). | 28622182 |
| Inflammation, PMF Regimen | Altered Intercellular Communication | Our data indicate that older age and high JAK2V617 allele burden are major determinants of inflammation in PMF, and are associated with disease progression. | 28622624 |
| Inflammation, Giant Cell Arteritis, Autoimmune Disorder, CTCAE | Altered Intercellular Communication | Giant cell arteritis is a systemic autoimmune disorder which involves inflammation of medium to large vessels. | 28623469 |
| Mitochondrial Damage, Inflammation, Dermatomyositis, Impaired | Altered Intercellular Communication | IFN-b-induced reactive oxygen species and mitochondrial damage contribute to muscle impairment and inflammation maintenance in dermatomyositis. | 28623559 |
| Inflammation, Demographics Domain, Autoimmune Diseases, physiopathological, Dermatomyositis | Altered Intercellular Communication | Dermatomyositis (DM) is an autoimmune disease associated with enhanced type I interferon (IFN) signalling in skeletal muscle, but the mechanisms underlying muscle dysfunction and inflammation perpetuation remain unknown. | 28623559 |
| Abnormality of mitochondrial metabolism, Myositis | Altered Intercellular Communication | In addition, mitochondrial dysfunctions increase ROS production that drive type I IFN-inducible gene expression and muscle inflammation, and may thus self-sustain the disease. | 28623559 |
| Inflammation, Ulcerative Colitis | Altered Intercellular Communication | These results suggest that the bowel inflammation observed in UC may have a causative effect of initiation of the immune response to the skin and development of the bullous skin lesions in LAGBD. | 28623863 |
| Inflammation | Altered Intercellular Communication | Our results provide evidence for MCP-1 involvement in the development of PVVs and indicate that inflammation could be implicated in the pathogenesis of this condition. | 28623996 |
| Communicable Diseases, Diverticulitis, Inflammation, Crohn Disease | Altered Intercellular Communication | Diverticulitis (DD) and Crohn's disease (CD) have overlapping features including bowel structuring, inflammation, and infection. | 28624054 |
| Inflammation, Myocardial | Altered Intercellular Communication | The functions of these proteins relate to myocardial stress, inflammation, pulmonary vascular cellular dysfunction and structural dysregulation, iron status, and coagulation. | 28624389 |
| Inflammation | Altered Intercellular Communication | Network analysis showed that in HFrEF interactions between biomarkers were mostly related to cardiac stretch, whereas in HFpEF, biomarker interactions were mostly related to inflammation. | 28624483 |
| Inflammation | Altered Intercellular Communication | Biomarker profiles in patients with acute HFrEF were mainly related to cardiac stretch and in HFpEF related to inflammation. | 28624483 |
| Cognitive, Nerve Degeneration | Altered Intercellular Communication | Brain inflammaging is increasingly considered as contributing to age-related cognitive loss and neurodegeneration. | 28624504 |
| Inflammation | Altered Intercellular Communication | We concluded that air pollution exposure was associated with systemic inflammation, oxidative stress and elevated blood pressure. | 28624750 |
| Inflammation, Metallosis | Altered Intercellular Communication | Only recently, however, it has the issue of metal-bone breakdown secondary to metal corrosion in situ come to light, raising concerns of possible long-term complications from the resulting metallosis and inflammation of spinal tissues. | 28624897 |
| Inflammation, Asthenia, Diarrhea, Exanthema | Altered Intercellular Communication | The most frequent AEs were diarrhea (94.9%), mucosal inflammation (64.1%), asthenia (53.8%) and rash (53.8%). | 28625629 |
| Inflammation, Craniosynostosis, Bacterial Infections | Altered Intercellular Communication | These findings suggest that IgD might contribute to enhancement mucosal immunity or inflammation or respond to bacterial infections in patients with CRS, especially CRSsNP. | 28625807 |
| ARCN1 gene, Pneumonitis | Altered Intercellular Communication | Individuals with COPD exposed to biomass burning demonstrated increased pulmonary inflammation and a reduction in the FEV1/FVC ratio, regardless of their engagement in PR. | 28625881 |
| Inflammation, Hyperplasia | Altered Intercellular Communication | Slight epidermal hyperplasia, dilated superficial thin-walled vessels and minimal to mild inflammation were seen in each. | 28627021 |
| Communicable Diseases, Hepatitis | Altered Intercellular Communication | These results suggest that the rs9514828 allele T may predispose to the liver inflammation in chronic HBV infection, and the rs9514828 and rs12583006 polymorphisms may combinatorially confer susceptibility to chronic HBV infection and resolution of the infection, possibly not through direct effect on serum BAFF levels. | 28627389 |
| Inflammation, Obesity | Altered Intercellular Communication | Dietary Red and Processed Meat Intake and Markers of Adiposity and Inflammation: The Multiethnic Cohort Study. | 28628401 |
| Inflammation, Primary malignant neoplasm | Altered Intercellular Communication | The potential influence of dietary factors on inflammation is important for cancer prevention. | 28628401 |
| Inflammation, Obesity | Altered Intercellular Communication | The current data suggest that the amount of excess body weight or the degree of adiposity may mediate the relations between dietary red and processed meat intake and serum biomarkers associated with obesity and inflammation. | 28628401 |
| Hepatosplenomegaly, Inflammation, Acne, Arthritis, Infectious, Pyoderma Gangrenosum, Pancytopenia, PAPPA gene, Arthritis, Failure (biologic function) | Altered Intercellular Communication | It has a phenotype distinct from classical pyogenic arthritis, pyoderma gangrenosum, and acne (PAPA) syndrome that includes severe systemic and cutaneous inflammation, hepatosplenomegaly, arthritis without sequelae, pancytopenia and failure to thrive. | 28628471 |
| Inflammation, Memory Loss, Depression, CTCAE | Altered Intercellular Communication | Depression, inflammation, and memory loss among Mexican Americans: analysis of the HABLE cohort. | 28629481 |
| Inflammation, Depression, CTCAE | Altered Intercellular Communication | This study explored the combined impact of depression and inflammation on memory functioning among Mexican-American adults and elders. | 28629481 |
| Inflammation | Altered Intercellular Communication | Among DepE positive, those who were high in inflammation (3rd tertile) were found to perform significantly worse on WMS-III LM I (F = 4.75, p = 0.003), WMS-III LM II (F = 8.18, p < 0.001), and CERAD List Learning (F = 17.37, p < 0.001) when compared to those low on inflammation (1st tertile). | 28629481 |
| Inflammation, millicurie | Altered Intercellular Communication | The combination of DepE positive and highest tertile of inflammation was associated with increased risk for MCI diagnosis (OR = 6.06; 95% CI = 3.9-11.2, p < 0.001). | 28629481 |
| Inflammation | Altered Intercellular Communication | Presence of elevated inflammation and positive DepE scores increased risk for worse memory among Mexican-American older adults. | 28629481 |
| Inflammation, millicurie | Altered Intercellular Communication | Additionally, the combination of DepE and high inflammation was associated with increased risk for MCI diagnosis. | 28629481 |
| Inflammation, Depression, CTCAE | Altered Intercellular Communication | This work suggests that depression and inflammation are independently associated with worse memory among Mexican-American adults and elders; however, the combination of both increases risk for poorer memory beyond either alone. | 28629481 |
| Inflammation | Altered Intercellular Communication | This may allow increased sensitivity for early diagnosis of synovial inflammation, monitoring of its dynamic changes under therapy and evaluation of true imaging remission. | 28629689 |
| Inflammation, metabolic disturbance, Obesity | Altered Intercellular Communication | Oxidative stress and inflammation are related to obesity, but the influence of metabolic disturbances on these parameters and their relationship with endoplasmic reticulum (ER) stress is unknown. | 28630460 |
| Inflammation, Stomach Carcinoma | Altered Intercellular Communication | Both bacterial virulence factors and host chronic inflammation are thought to promote gastric cancer development. | 28631561 |
| Inflammation, Stomach Carcinoma, Neoplasms | Altered Intercellular Communication | These results suggested that dysregulation of follicular helper T subsets in gastric cancer patients, characterized by increased Th1-follicular helper T cells, contributed to inflammation and tumor development. | 28631561 |
| Inflammation, Depression, CTCAE, Cerebrovascular accident | Altered Intercellular Communication | Depression is a common complication after stroke, and inflammation may be a pathophysiological mechanism. | 28632121 |
| Inflammation, Depression, CTCAE, Cerebrovascular accident | Altered Intercellular Communication | This suggests that inflammation contributes differently to the development of depression after stroke depending on the time of onset. | 28632121 |
| Sepsis, Fever, CTCAE, Inflammatory dermatosis | Altered Intercellular Communication | We report a case of a 59-year-old man who presented with fever, sepsis, and left cervicothoracic cutaneous inflammation 13 months after implantation of Jarvik 2000 device. | 28632696 |
| Inflammation, Neoplasms, Communicable Diseases, Traumatic injury, Facial paralysis | Altered Intercellular Communication | Facial nerve paralysis can occur due to infection, inflammation, trauma, surgery, and tumors. | 28632885 |
| Necrotizing granulomatous inflammation, Cutaneous nodular amyloidosis, Sarcoidosis | Altered Intercellular Communication | Nodular cutaneous amyloidoma of the extremity secondary to chronic granulomatous inflammation in setting of sarcoidosis. | 28632948 |
| Inflammation, Hypertension, CTCAE, Traumatic injury, Diabetes Mellitus | Altered Intercellular Communication | Soft tissue amyloidomas on the extremities have been associated with chronic inflammation, particularly when accompanied by AA-type amyloid deposition as seen in local trauma, surgery, hypertension and diabetes. | 28632948 |
| Necrotizing granulomatous inflammation, Sarcoidosis | Altered Intercellular Communication | We hypothesize that this process developed secondary to the chronic granulomatous inflammation of sarcoidosis. | 28632948 |
| Paraneoplastic Endocrine Syndromes, Neoplasms | Altered Intercellular Communication | The majority of these tumors are found incidentally during screening colonoscopies and rarely are associated with symptoms of hormonal syndrome, even during the advanced stage. | 28633725 |
| Inflammation | Altered Intercellular Communication | The specific mechanism for its occurrence is still not entirely clear, and it is believed at present that platelet activation and inflammation play a pivotal role in developing no-reflow. | 28633762 |
| Inflammation, Lymphopenia | Altered Intercellular Communication | Both increased mean platelet volume (MPV), which is a platelet activation marker, and lymphopenia, which is an inflammation marker, have been linked to adverse events and poor prognosis after STEMI. | 28633762 |
| Inflammation, Tooth Loss | Altered Intercellular Communication | Diet-borne systemic inflammation is associated with prevalent tooth loss. | 28633943 |
| Inflammation, Tooth Loss | Altered Intercellular Communication | The deleterious effect of cariogenic dietary patterns on tooth loss is well characterized, but the contribution of diet-borne systemic inflammation to loss of teeth remains uncharted. | 28633943 |
| Inflammation, Nasal Polyps, Chronic sinusitis, Craniosynostosis | Altered Intercellular Communication | Chronic rhinosinusitis with nasal polyps (CRSwNP) has been categorized into 2 subtypes in the Asian population: eosinophilic chronic rhinosinusitis (ECRS; similar to CRSwNP in Western countries) and non-ECRS (characterized by inflammation dominated by T-helper cell type 1). | 28634018 |
| Infection | Altered Intercellular Communication | SIRT3 deficiency has been reported to promote chronic inflammation-related disorders, but whether SIRT3 impacts on innate immune responses and host defenses against infections remains essentially unknown. | 28634345 |
| Sepsis, Inflammation | Altered Intercellular Communication | This finding may underlie the adverse cardiovascular events in patients admitted with sepsis, possibly requiring alteration of antiplatelet regimen during the inflammation period. | 28635374 |
| Inflammation, Retinitis Pigmentosa | Altered Intercellular Communication | Chronic inflammation is involved in retinitis pigmentosa (RP). | 28636270 |
| Inflammatory Bowel Diseases, Primary malignant neoplasm, Gastrointestinal inflammation | Altered Intercellular Communication | Inflammatory bowel disease (IBD) is characterized by recurrent or chronic inflammation of the gastrointestinal tract, which results in increased risk of developing cancer. | 28637107 |
| Inflammation, Non-alcoholic Fatty Liver Disease | Altered Intercellular Communication | The pathogenesis of non-alcoholic fatty liver disease (NAFLD) is attributed to a "multi-hits hypothesis" involving insulin resistance, oxidative stress and inflammation. | 28637594 |
| Inflammation | Altered Intercellular Communication | NR4A3 expression is also increased at sites of neutrophilic inflammation in a human model of intradermal inflammation. | 28637666 |
| Fibrosis Assessment, Retractile Mesenteritis, Orbital Pseudotumor | Altered Intercellular Communication | BACKGROUND Sclerosing mesenteritis (SM) is a rare idiopathic inflammation and fibrosis of the mesentery. | 28638005 |
| Inflammation, Osage language, Hypoxemia, Bipolar Disorder, Sleep Apnea, Obstructive | Altered Intercellular Communication | This study examined the association between depressive symptoms, as well as depressive symptom dimensions, and three candidate biological pathways linking them to Obstructive sleep apnea (OSA): (1) inflammation; (2) circulating leptin; and (3) intermittent hypoxemia. | 28639107 |
| Inflammation, Fibrosis Assessment | Altered Intercellular Communication | However, the exact factors that contribute to chronic inflammation and subsequently fibrosis progression are still unknown. | 28639412 |
| Inflammation, Ulcerative Colitis | Altered Intercellular Communication | PET/MRI for evaluating subclinical inflammation of ulcerative colitis. | 28640521 |
| Inflammation, Ulcerative Colitis | Altered Intercellular Communication | To explore the utility of integrated positron emission tomography (PET) / magnetic resonance imaging (MRI) for evaluating subclinical inflammation in patients with ulcerative colitis (UC). | 28640521 |
| Inflammation | Altered Intercellular Communication | Qualitative MRI score, PET activity grade, and PET/MRI score were also significantly higher in the colonic segments with active inflammation (P < 0.05). | 28640521 |
| Inflammation, Ulcerative Colitis | Altered Intercellular Communication | PET/MRI is a potentially useful tool in identifying subclinical inflammation in patients with UC. | 28640521 |
| Inflammation, Neuropathogenesis, Trauma, Nervous System | Altered Intercellular Communication | They produce cytokines/chemokines and viral proteins that promote inflammation and neuronal damage, playing a key role in HIV neuropathogenesis. | 28640909 |
| Inflammation, Weight decreased, Acute inflammation | Altered Intercellular Communication | C5BL/6 female mice receiving dextran sodium sulfate in their drinking water develop an acute inflammatory colitis within 7d, with weight loss, histopathologic signs of inflammation, and colonic expression of inflammatory cytokines. | 28641125 |
| Inflammation, Dental Plaque | Altered Intercellular Communication | Contrast extravasation rate, or Ktrans, derived from kinetic modeling of adventitial enhancement, has been correlated with plaque neovascularization and inflammation. | 28641819 |
| Inflammation, Electrocardiogram: myocardial infarction (finding) | Altered Intercellular Communication | Ferumoxytol-enhanced magnetic resonance imaging assessing inflammation after myocardial infarction. | 28642288 |
| Inflammation, Edema, Cardiac | Altered Intercellular Communication | This observed pattern of cellular inflammation is distinct, and provides complementary information to the more prolonged myocardial oedema detectable using T2 mapping. | 28642288 |
| Inflammation, Inflammatory disorder | Altered Intercellular Communication | GlycA is a new composite measure of systemic inflammation and a predictor of many inflammatory diseases. | 28642810 |
| Cytomegalovirus Infections, Asthma, Inflammation | Altered Intercellular Communication | We conclude that CMV infection is associated with asthma and may contribute to the pathogenesis of asthmatic inflammation. | 28643373 |
| Degenerative polyarthritis, Inflammation | Altered Intercellular Communication | The osteoarthritis (OA) progression is now considered to be related to inflammation. | 28643466 |
| Inflammation, Oral Manifestations | Altered Intercellular Communication | NO2, which is poorly soluble in water, penetrates deep into the bronchial tree, producing asthmatic manifestations such as inflammation and increased mucus production as a result of high gaseous concentrations in the lung parenchyma. | 28644724 |
| Cerebrovascular Disorders, Inflammation | Altered Intercellular Communication | Circulation inflammation markers such as high-sensitive C-reactive protein (hsCRP) and lipoprotein-associated phospholipase A2 (Lp-PLA2) are considered as predictors of cerebral and cardiac vascular diseases. | 28644968 |
| Upper Respiratory Infections | Altered Intercellular Communication | This study suggested low ambient temperature, fine PM, and coarse PM might elevate the levels of respiratory inflammation. | 28645522 |
| Inflammation, Asthma | Altered Intercellular Communication | Biomarkers of airway and systemic inflammation in obese asthmatic paediatric patients. | 28645880 |
| Airway structure, Inflammation, Asthma | Altered Intercellular Communication | It is thought that airway inflammation is more common in obese asthmatic patients because inflammation is harder to control and does not respond well to glucocorticoid treatment. | 28645880 |
| Inflammation, Asthma, Obesity | Altered Intercellular Communication | This study's aim was to investigate the effect of obesity on airway and systemic inflammation in children with asthma and to identify the biomarkers that play a role in this inflammation. | 28645880 |
| Inflammation, Asthma | Altered Intercellular Communication | Larger studies with sputum and BAL examinations are required to determine the potential of biomarkers for identifying inflammation in obese asthmatic children. | 28645880 |
| Hypertension, CTCAE | Altered Intercellular Communication | Immuno-inflammation plays a major role in the process of hypertension. | 28646855 |
| Inflammation | Altered Intercellular Communication | Mice lacking cIAP1 and either cIAP2 or XIAP die in utero, and myeloid lineage-specific deletion of all IAPs causes sterile inflammation, but their role in the skin is unknown. | 28647349 |
| Cessation of life, Dermatitis | Altered Intercellular Communication | We generated epidermal-specific IAP-deficient mice and found that combined genetic deletion of cIAP1 (epidermal knockout [EKO]) in keratinocytes and ubiquitous cIAP2 deletion (cIap1EKO/EKO.cIap2-/-) caused profound skin inflammation and keratinocyte death, lethal by postpartum day 10. | 28647349 |
| Inflammation | Altered Intercellular Communication | This induced a toxic epidermal necrolysis-like local inflammation, which mirrored the phenotype seen in cIap1EKO/EKO.cIap2-/- mice. | 28647349 |
| Dermatitis | Altered Intercellular Communication | This work therefore refines our molecular understanding of inflammatory signaling in the skin and defines potential targets for treating skin inflammation. | 28647349 |
| Dermatitis | Altered Intercellular Communication | This work therefore refines our molecular understanding of inflammatory signaling in the skin and defines potential targets for treating skin inflammation. | 28647349 |
| Degenerative polyarthritis, Inflammation, Synovitis | Altered Intercellular Communication | Despite this the recent studies are shown synovitis and low inflammation to have a role in OA pathophysiology. | 28647559 |
| Inflammation, Atherosclerosis | Altered Intercellular Communication | Associations of Cigarette Smoking With Subclinical Inflammation and Atherosclerosis: ELSA-Brasil (The Brazilian Longitudinal Study of Adult Health). | 28647689 |
| Inflammation, Atherosclerosis | Altered Intercellular Communication | We examined the association of smoking status, burden, time since quitting, and intensity, with markers of inflammation and subclinical atherosclerosis. | 28647689 |
| Inflammation, Carotid Intima-Media Thickness, Atherosclerosis | Altered Intercellular Communication | Strong associations were observed between smoking status, burden, and intensity with inflammation (hsCRP) and subclinical atherosclerosis (carotid intima-media thickness, ankle-brachial index, CAC). | 28647689 |
| Malignant neoplasm of urinary bladder | Altered Intercellular Communication | Integrative Assessment of Pretreatment Inflammation-, Nutrition-, and Muscle-Based Prognostic Markers in Patients with Muscle-Invasive Bladder Cancer Undergoing Radical Cystectomy. | 28647740 |
| Inflammation | Altered Intercellular Communication | The present BRONJ POE revealed the rapid progress of bony wound healing through increased molecular signaling for inflammation, angiogenesis, and osteogenesis compared to the control. | 28647850 |
| Inflammation | Altered Intercellular Communication | LM disclosed a low-grade chronic inflammation and birefringent particles in most sections. | 28648703 |
| Refractory anemias, Inflammation | Altered Intercellular Communication | Synovial inflammation is a major feature of RA and is associated with leukocyte recruitment. | 28648867 |
| Bacterial peritonitis | Altered Intercellular Communication | The in-vivo effects were evaluated by circulatory inflammation-associated cytokine levels in mice with septic peritonitis induced by cecal ligation and puncture (CLP) operation. | 28648928 |
| Drug Eruptions, Inflammation | Altered Intercellular Communication | The thymus and activation-regulated chemokine (TARC) level in serum at an early stage of a drug eruption is a prognostic biomarker of severity of systemic inflammation. | 28648978 |
| Drug Eruptions, Inflammation | Altered Intercellular Communication | Serum TARC levels correlate well with indicators of systemic inflammation and of disease severity among patients with a drug eruption except SJS/TEN. | 28648978 |
| Drug Eruptions, Inflammation | Altered Intercellular Communication | Serum TARC may be a prognostic biomarker of severity of inflammation in drug eruptions. | 28648978 |
| Inflammation, Brain Injuries | Altered Intercellular Communication | Yet, emerging evidence suggests that viral suppression will inadequately control inflammation and mitigate risk for progressive brain injury. | 28650401 |
| Inflammation, Fibrosis Assessment | Altered Intercellular Communication | Adipose tissues secrete adipokines, peptides with potent effects modulating fibrosis, inflammation, and vascular homeostasis. | 28651038 |
| Inflammation | Altered Intercellular Communication | Clinical disease activity consistently declined, but faecal calprotectin and circulating markers of inflammation did not. | 28651829 |
| Inflammation, Hematoma, Atrial Premature Complexes | Altered Intercellular Communication | If pregnancy continues, these haematomas may act as a source of oxidative stress, promoting senescence and weakening of the membranes, and stimulating inflammation in the uterine wall and premature contractions. | 28651899 |
| Uremia, Inflammation | Altered Intercellular Communication | Inflammation and uremia negatively impact immune function in this population, but specific pathways involved in TB immunity have not been identified. | 28651949 |
| Inflammation | Altered Intercellular Communication | Surprisingly, neither the gd phenotype nor its function was associated with plasma markers of inflammation or microbial translocation. | 28651949 |
| Brain Hypoxia, Inflammation, Reperfusion Injury, Trauma, Nervous System | Altered Intercellular Communication | Transient cerebral hypoxia may induce neuronal injury through an ischemia-reperfusion (I/R) response, with a subsequent activation of inflammation and coagulation-fibrinolysis. | 28652057 |
| Inflammation, Pain Distress Question | Altered Intercellular Communication | Proteins associated with DD tended to be related to inflammation (eg, cystatin C) regardless of pain status. | 28652204 |
| Inflammation, Nerve injury | Altered Intercellular Communication | This study shows that CSF can be used to study mechanisms underlying painful DD in humans, and suggests that while painful DD is associated with nerve injury, inflammation itself is not sufficient to develop LBP. | 28652204 |
| Inflammation, Nerve injury, Pain Distress Question | Altered Intercellular Communication | While DD was related to inflammation regardless of pain status, painful degeneration was associated with markers linked to nerve injury. | 28652204 |
| Autoimmune Diseases, Inflammation | Altered Intercellular Communication | These results uncover a possible pathway for LTF-ICs perpetuating local inflammation and contributing to the pathogenesis of autoimmune diseases by triggering activation of infiltrating monocytes or tissue macrophages in vivo. | 28652573 |
| Inflammation, Chronic Kidney Diseases | Altered Intercellular Communication | Markers of inflammation and iron status were positively associated with serum hepcidin level, regardless of CKD stage. | 28652624 |
| Acute cholangitis, Cholangitis | Altered Intercellular Communication | In another case, signs of bile duct inflammation caused by acute cholangitis were evident. | 28652659 |
| Granulomatous inflammation, Gossypiboma | Altered Intercellular Communication | In conclusion, based on this case, gossypiboma (or granulomatous inflammation in response to foreign bodies) should be also considered in differential diagnosis of intrathoracic lymph nodes with PET positivity in a previously operated patient. | 28653494 |
| Inflammation, Prostate carcinoma | Altered Intercellular Communication | Periprostatic adipose inflammation is associated with high-grade prostate cancer. | 28653675 |
| Inflammation, Prostate carcinoma, Obesity | Altered Intercellular Communication | Obesity, a cause of subclinical inflammation, is associated with increased risk of high-grade prostate cancer (PC) and poor outcomes. | 28653675 |
| Inflammation, Aggressive behavior, Obesity | Altered Intercellular Communication | Whether inflammation occurs in periprostatic white adipose tissue (WAT), and contributes to the negative impact of obesity on PC aggressiveness, is unknown. | 28653675 |
| Inflammation | Altered Intercellular Communication | The primary objective was to examine the prevalence of periprostatic WAT inflammation defined by the presence of crown-like structures (CLS-P) as detected by CD68 immunohistochemistry. | 28653675 |
| Inflammation, Neoplasms | Altered Intercellular Communication | Periprostatic WAT inflammation was identified in 49.7% of patients and associated with higher BMI (P=0.02), larger adipocyte size (P=0.004) and Gleason grade groups IV/V tumors (P=0.02). | 28653675 |
| Inflammation | Altered Intercellular Communication | The relationship between WAT inflammation and high Gleason grade remained significant after adjusting for BMI (P=0.04). | 28653675 |
| Inflammation, Acute lymphocytic leukemia | Altered Intercellular Communication | Young adult survivors of childhood acute lymphoblastic leukemia show evidence of chronic inflammation and cellular aging. | 28654149 |
| Inflammation, Acute lymphocytic leukemia | Altered Intercellular Communication | The authors investigated whether young adult survivors of childhood acute lymphoblastic leukemia (ALL) have a biologic phenotype of cellular ageing and chronic inflammation. | 28654149 |
| Inflammation, Acute lymphocytic leukemia | Altered Intercellular Communication | Asymptomatic young adult survivors of childhood ALL demonstrate a biologic profile of chronic inflammation and telomere attrition, consistent with an early onset of cellular processes that drive accelerated aging. | 28654149 |
| methyldopa, Inflammation | Altered Intercellular Communication | It has been suggested that systemic inflammation increases the risk of age-related macular degeneration (AMD). | 28655032 |
| methyldopa, Malignant Peripheral Nerve Sheath Tumor, Inflammation | Altered Intercellular Communication | Our results suggest that patients with MPNs are at increased risk of AMD, supporting the possibility that systemic inflammation is involved in the pathogenesis of AMD. | 28655032 |
| Inflammation | Altered Intercellular Communication | We investigated the impact of specific neuroinflammatory markers on human neurons to identify potential therapeutic targets for neuroprotection against chronic inflammation. | 28655310 |
| Tubulitis Assessment, Interstitial inflammation | Altered Intercellular Communication | Indication biopsies after immunosuppression reduction showed an increase in tubulitis and interstitial inflammation score compared to those at the time of the PVN diagnosis. | 28655392 |
| Tubulitis Assessment, Viremia, Interstitial inflammation | Altered Intercellular Communication | Surveillance biopsies 1 year after transplantation revealed resolution of interstitial inflammation and tubulitis accompanied by clearance of BK viremia in 4 patients (50%), including 1 patient with rejection. | 28655392 |
| Interstitial inflammation | Altered Intercellular Communication | One patient showed residual interstitial inflammation after viral clearance. | 28655392 |
| Tubulitis Assessment, Interstitial inflammation | Altered Intercellular Communication | PVN-associated interstitial inflammation and tubulitis cannot be differentiated morphologically from T-cell-mediated tubulointerstitial rejection. | 28655392 |
| Tubulitis Assessment, Interstitial inflammation | Altered Intercellular Communication | Significant interstitial inflammation and tubulitis in PVN under low-dose immunosuppression might represent immune reconstitution injury, which is reduced after successful BKV clearance from the serum and kidney. | 28655392 |
| Eosinophilic esophagitis, Esophagitis, Immune-mediated, "Extra-osseous Ewings sarcoma | Altered Intercellular Communication | Eosinophilic esophagitis (EoE) is a chronic immune-mediated disease characterized by esophageal inflammation and dysfunction. | 28655543 |
| APP gene, Inflammation | Altered Intercellular Communication | Inflammation is an important process in AAA formation and increases levels of oxidative stress. | 28655550 |
| Crohn Disease, Inflammation | Altered Intercellular Communication | Routine clinical care for Crohn's disease (CD) outpatients does not cover the assessment of body composition (BC); although this disease (because of inflammation, surgeries, lack of physical activity and appetite) may have a severe impact on lean body mass. | 28656973 |
| Inflammation, Chronic inflammation | Altered Intercellular Communication | This may reflect a switch from acute to chronic inflammation, where chronic inflammation is reflected in the serum after the acute phase response subsides. | 28657165 |
| Calcified (qualifier), Inflammation, Ulceration, CTCAE, Pain Distress Question | Altered Intercellular Communication | Subcutaneous calcifications can lead to complications, including pain, inflammation, ulceration and immobilization. | 28660279 |
| Pituitary Adenoma | Altered Intercellular Communication | Normal hormonal status was found, consistent with the diagnosis of non-functioning pituitary adenoma. | 28660992 |
| Inflammation | Altered Intercellular Communication | Evaluation of ultrasmall superparamagnetic iron-oxide (USPIO) enhanced MRI with ferumoxytol to quantify arterial wall inflammation. | 28662398 |
| Inflammation, Dental Plaque, atherosclerotic | Altered Intercellular Communication | Inflammation in atherosclerotic plaques is an important determinant of plaque vulnerability, and can be detected non-invasively using ultra-small superparamagnetic iron-oxide (USPIO) enhanced MRI. | 28662398 |
| Inflammation, Plaque, Atherosclerotic | Altered Intercellular Communication | As USPIO and 18F-FDG uptake in atherosclerotic plaque do not correlate in this cohort, these agents may visualize different pathophysiological aspects of plaque inflammation. | 28662398 |
| Inflammation, Disease | Altered Intercellular Communication | Our data showed that IL-20 is independently associated with RA disease activity and may be triggered by TLR ligands at local sites of inflammation. | 28662439 |
| Rheumatoid Arthritis, Inflammation | Altered Intercellular Communication | High triglycerides and low high-density lipoprotein cholesterol lipid profile in rheumatoid arthritis: A potential link among inflammation, oxidative status, and dysfunctional high-density lipoprotein. | 28662934 |
| Refractory anemias, Inflammation, Rheumatoid Arthritis | Altered Intercellular Communication | The interactions between inflammation and lipid profile in rheumatoid arthritis (RA) are poorly understood. | 28662934 |
| TG gene, Inflammation, Refractory anemias | Altered Intercellular Communication | Since recent findings suggest a role for TG and TG-rich lipoproteins (TRL) on inflammation, we aimed to evaluate a combined lipid profile characterized by high TG and low high-density lipoprotein cholesterol levels (TGhighHDLlow) in RA. | 28662934 |
| Refractory anemias, Inflammation, physiopathological | Altered Intercellular Communication | The TGhighHDLlow profile is associated with systemic inflammation, decreased PON1 activity, and poor clinical outcome on TNFa blockade in RA, suggesting a role of TRL and HDL dysfunction as the missing link between inflammation and lipid profile. | 28662934 |
| Inflammation, Atherosclerosis | Altered Intercellular Communication | We aimed to analyse the association between inflammation and subclinical atherosclerosis in HIV patients with low Framingham risk score. | 28664622 |
| Carotid Atherosclerosis, Inflammation | Altered Intercellular Communication | Well-controlled HIV patients with low Framingham risk score have a high prevalence of subclinical carotid atherosclerosis, and the main risk factors are age and inflammation. | 28664622 |
| Inflammation, Fibrosis Assessment | Altered Intercellular Communication | In kidney transplant recipients, the addition of 2 ug/day paricalcitol to RAS inhibition lowers IL-6 and TGF-b concentrations, which may be beneficial for reducing graft inflammation and fibrosis. | 28664839 |
| Inflammation, Hyperbilirubinemia, Liver Dysfunction | Altered Intercellular Communication | We present the case of a 6-year-old child with severe hyperbilirubinemia due to congestive liver dysfunction, complicated by persistent inflammation, immunosuppression and catabolism syndrome (PICS). | 28665446 |
| Nasal Polyps | Altered Intercellular Communication | We evaluated the prognostic value of nasal cytology and clinical factors in predicting nasal polyp (NP) development in patients with history of nonallergic chronic sinonasal inflammation. | 28665504 |
| Inflammation | Altered Intercellular Communication | According to the inclusion criteria we enrolled 84 cases with persistent eosinophilic nonallergic sinonasal inflammation (group A) and 106 cases with neutrophilic inflammation (group B), both without evidence of NPs at the baseline. | 28665504 |
| Inflammation | Altered Intercellular Communication | We considered as controls 105 patients affected by nonallergic noninfectious vasomotor rhinitis without evidence of inflammation at nasal cytology (group C). | 28665504 |
| Aggressive course, Eosinophilic inflammation | Altered Intercellular Communication | Our data confirm that detection of nasal eosinophilic inflammation represents an early marker for identification of a more aggressive inflammatory phenotype. | 28665504 |
| Inflammation | Altered Intercellular Communication | Diet quality, inflammation, and the ankle brachial index in adults with or without cardiometabolic conditions. | 28666597 |
| Granulomatous inflammation, Anxiety, CTCAE 3.0 | Altered Intercellular Communication | Analyzing tissue specimens with frozen section has been shown in the past to demonstrate granulomatous inflammation and yeast forms of the organism; however, as demonstrated in this patient, the presence of pseudoepitheliomatous cells may deceptively appear as malignant, causing substantial concern and anxiety. | 28666674 |
| Inflammation | Altered Intercellular Communication | Additionally, the numbers of CD4+ and Foxp3+ T cells as well as the expression of IL-10, TGF-b1, FOXP3 and INF-g were positively correlated with the degree of H. pylori density and chronic inflammation. | 28666843 |
| Inflammation, Hypertension, CTCAE | Altered Intercellular Communication | The Contribution of Inflammation to the Development of Hypertension Mediated by Increased Arterial Stiffness. | 28666991 |
| Inflammation, Hypertension, CTCAE | Altered Intercellular Communication | The mechanisms underlying the possible contribution of chronic inflammation to the development of hypertension remain unclear. | 28666991 |
| Inflammation, Hypertension, CTCAE, Abnormality of the vasculature | Altered Intercellular Communication | We examined the longitudinal association of inflammation with the progression of vascular and/or renal abnormalities in the development of hypertension. | 28666991 |
| Arterial Stiffness, Inflammation, Hypertension, CTCAE | Altered Intercellular Communication | In middle-aged Japanese men without hypertension at study baseline, long-term active inflammation appears to be associated with a longitudinal increase of arterial stiffness. | 28666991 |
| Arterial Stiffness, Inflammation, Hypertension, CTCAE | Altered Intercellular Communication | Thus, systemic inflammation may play a role in the pathogenesis of hypertension by the progression of arterial stiffness. | 28666991 |
| Inflammation, Osteopenia | Altered Intercellular Communication | Periodontal diseases manifest by the formation of deep pockets between the gingiva and teeth where multispecies bacterial biofilms flourish, causing inflammation and bone loss. | 28667248 |
| Inflammation | Altered Intercellular Communication | Moreover, Itgb6 -/- mice display increased periodontal inflammation compared to wild-type mice. | 28667248 |
| Inflammation, Periodontal Diseases | Altered Intercellular Communication | We hypothesized that bacterial biofilms present in the periodontal pockets suppress avb6 integrin levels in periodontal disease and that this change aggravates inflammation. | 28667248 |
| Inflammation, Carcinogenesis | Altered Intercellular Communication | In conclusion, this study suggests that obesity-related systemic low-grade inflammation may play an important role in the early stages of colorectal carcinogenesis. | 28667300 |
| Cessation of life, Inflammation | Altered Intercellular Communication | Analysis of sWAT from mice of various ages showed senescence, persistent DNA damage and cell death that preceded macrophage infiltration, and systemic inflammation. | 28667315 |
| Hereditary Autoinflammatory Diseases, Inflammation | Altered Intercellular Communication | It is a rare condition, particularly in the pediatric population, and has recently been proposed to be an autoinflammatory disease that occurs due to innate immune system dysfunction, involving several cytokines, which causes abnormally increased inflammation. | 28668093 |
| Abscess, pathologic fistula, Inflammation, Edema | Altered Intercellular Communication | Abscesses, fistulous or sinus tracts, signal alterations and contrast enhancement in keeping with an inflammation and edema in the perianal region were recorded. | 28668427 |
| Perianal | Altered Intercellular Communication | In 10 of these 16 patients there was also extensive inflammatory signal alterations in perianal and/or perineal soft tissues. | 28668427 |
| Abscess | Altered Intercellular Communication | There were abscesses in labium majus in two patients and in one patient there were perineal abscesses with accompanying inflammatory signal alterations. | 28668427 |
| Perianal | Altered Intercellular Communication | There were only inflammatory signal alterations with contrast enhancement in perianal or subcutaneous tissues. | 28668427 |
| Degenerative polyarthritis, Inflammation | Altered Intercellular Communication | Inflammation is an important regulator of osteoarthritis (OA), but the molecular and cellular mechanisms regulating this process are not well defined. | 28668542 |
| Degenerative polyarthritis, Acute and chronic inflammation | Altered Intercellular Communication | Our results indicate that NK cells from the synovium of patients with OA, which present an immunoregulatory non-cytotoxic phenotype, show different phenotype comparing with NK cells from peripheral blood, especially expressing granzyme A, a pro-inflammatory molecule which may contribute to the establishment of chronic articular inflammation in this type of patients. | 28668542 |
| Demographics Domain, Diabetes Mellitus, Neurogenic arthropathy, Osteopenia, Peripheral Neuropathy | Altered Intercellular Communication | Inflammation-mediated foot osteopenia may play a pivotal role in the etiogenesis, pathogenesis, and therapeutic outcomes in individuals with diabetes mellitus (DM), peripheral neuropathy (PN), and Charcot neuroarthropathy (CN). | 28668579 |
| Inflammation, Metabolic Diseases, Primary malignant neoplasm | Altered Intercellular Communication | Osteopontin is a secreted extracellular glyco-phosphoprotein that has been associated with inflammation, metabolic disorders and cancer. | 28668580 |
| Carcinogenesis, Gastrointestinal inflammation | Altered Intercellular Communication | Thrombospondin-1 (TSP1) is correlated with carcinogenesis occurring in cases of intestinal inflammation. | 28668845 |
| Inflammation, Vasospasm, Vascular System Injuries | Altered Intercellular Communication | Severe vasospasm was thought to have occurred because the vascular injury caused by the stent retriever in the vessel had a marked inflammation background. | 28669652 |
| Diabetes Mellitus, Non-Insulin-Dependent, Immune-mediated | Altered Intercellular Communication | The aim of this trial was to determine the efficacy of a resistant dextrin on immune-mediated inflammation and hypothalamic-pituitary-adrenal axis in women with type 2 diabetes mellitus (T2DM). | 28669666 |
| Inflammation, Fibrosis Assessment, Hypertrophy | Altered Intercellular Communication | MiR-21 is a fibrosis-associated miRNA and promotes inflammation in LF tissue by activating IL-6 expression, leading to LF fibrosis and hypertrophy. | 28669725 |
| Pain Distress Question, Sinusitis | Altered Intercellular Communication | There was no difference in the sinus inflammation scores in CT findings, based on the presence of pain. | 28670951 |
| Inflammation, Ocular Hypotension, Serous choroidal detachment, Hyphema, Unspecified visual loss | Altered Intercellular Communication | Complications included hypotony, IOP spike, hyphema, serous choroidal detachment, persistent inflammation, and vision loss. | 28671927 |
| Inflammation, Unspecified visual loss | Altered Intercellular Communication | At 3 months, inflammation was still present in 46% of eyes and vision loss of at least 1 line was present in 41% of eyes. | 28671927 |
| Inflammation | Altered Intercellular Communication | Arterial wall thickening, stimulated by low-grade systemic inflammation, underlies many cardiovascular events. | 28673375 |
| Cessation of life, Inflammation, Atherosclerosis | Altered Intercellular Communication | These results support the hypothesis that a pro-inflammatory diet increases systemic inflammation leading to development and progression of atherosclerosis and eventual ASVD-related death. | 28673375 |
| Inflammation, Movement Disorders, Parkinsonian Disorders, SLC12A3 gene | Altered Intercellular Communication | Parkinsonism, the most common movement disorder in NCC, is not related to specific localization of the lesions but the patients show widespread and large lesions, associated with inflammation and distortions of brain structures. | 28673613 |
| Inflammation, Hyperparathyroidism | Altered Intercellular Communication | Correction of 25-OH-vitamin D deficiency improves control of secondary hyperparathyroidism and reduces the inflammation in stable haemodialysis patients. | 28673686 |
| Inflammation | Altered Intercellular Communication | In terms of malnutrition-inflammation status, a decrease in C-reactive protein was noted, although other microinflammation parameters, such as activated monocytes (CD14+/CD16+ and CD 14++/CD16+) were unchanged. | 28673686 |
| Inflammation, Hepatobiliary Disorder, Injury of liver, Fibrosis Assessment | Altered Intercellular Communication | Vascular adhesion protein-1 (VAP-1) drives inflammation in liver disease, and provision of an antibody against VAP-1 blunts fibrosis in murine models of liver injury. | 28674140 |
| vascular inflammations, Atherosclerosis | Altered Intercellular Communication | Oxidative stress is involved in vascular inflammation, the process of atherosclerosis. | 28674322 |
| Inflammation, Arthritis | Altered Intercellular Communication | Dual energy CT iodine map for delineating inflammation of inflammatory arthritis. | 28674965 |
| Arthritis | Altered Intercellular Communication | * Dual-energy CT iodine mapping can delineate inflammation of peripheral inflammatory arthritis. | 28674965 |
| Inflammation, Microvascular Angina | Altered Intercellular Communication | Inflammation is one of the mechanisms underlying cardiac syndrome X (CSX). | 28675064 |
| syphilis infection, Intraocular inflammation, Uveitis | Altered Intercellular Communication | Uveitis (intraocular inflammation) usually occurs in the secondary or later stages of syphilis infection and is sight-threatening. | 28675181 |
| Inflammation, Fibrosis Assessment, Degenerative disorder, Aortic Valve Stenosis | Altered Intercellular Communication | Recent studies suggest that aortic stenosis is not a passive degenerative disease, but an active process involving several pathways, including lipid infiltration, chronic inflammation, fibrosis formation, osteoblast activation, and active valve mineralisation. | 28675194 |
| Inflammation, Cardiovascular Diseases | Altered Intercellular Communication | This article is part of a themed section on Targeting Inflammation to Reduce Cardiovascular Disease Risk. | 28675448 |
| Inflammation, Hypersensitivity | Altered Intercellular Communication | Mucosal inflammation, altered neuroendocrine activity and intraluminal metabolic processes may contribute to the development of visceral hypersensitivity. | 28675524 |
| Inflammation, Epilepsy | Altered Intercellular Communication | Processes implicating brain inflammation have been increasingly observed in epilepsy research. | 28675559 |
| Encephalomyelitis, Inflammation, Comorbidity, Epilepsy | Altered Intercellular Communication | Herein we discuss the progress on animal models of epilepsy and comorbidities that inform us on the potential role of inflammation in epileptogenesis and comorbidity pathogenesis in rodent models of West syndrome and the Theiler's murine encephalomyelitis virus (TMEV) mouse model of viral encephalitis-induced epilepsy. | 28675559 |
| Inflammation | Altered Intercellular Communication | The present study showed the epidemiology of frailty, and the strong connection to aging, increased CIMT, enhanced inflammation and decreased femoral neck BMD. | 28675572 |
| Inflammation, Atherosclerosis | Altered Intercellular Communication | These results suggested that preclinical atherosclerosis, inflammation and femoral neck BMD were potentially modifiable risk factors for frailty. | 28675572 |
| Inflammation, Fibrosis Assessment | Altered Intercellular Communication | Early subclinical inflammation in kidney transplants is associated with later graft fibrosis and dysfunction. | 28675676 |
| Inflammation, Dysbiosis | Altered Intercellular Communication | Increased gut permeability ("leaky gut") has been proposed as a potential contributor to age-related inflammation and gut dysbiosis. | 28676292 |
| Inflammation | Altered Intercellular Communication | To investigate the hypothesis that an aging-associated leaky gut is linked to the age-related inflammation and frailty. | 28676292 |
| Inflammation | Altered Intercellular Communication | These data suggest that a leaky gut may play a critical role in the development of age-related inflammation and frailty. | 28676292 |
| Inflammation, Malnutrition, Anemia | Altered Intercellular Communication | Anemia Is Correlated with Malnutrition and Inflammation in Croatian Peritoneal Dialysis Patients: A Multicenter Nationwide Study. | 28676512 |
| palladium, Inflammation, Malnutrition, Anemia | Altered Intercellular Communication | Malnutrition, inflammation, and anemia are common in peritoneal dialysis (PD) patients. | 28676512 |
| palladium, Malnutrition, Anemia | Altered Intercellular Communication | In this study, correlations between Malnutrition Inflammation Score (MIS), laboratory and anthropometric parameters, and anemia indices in Croatian PD patients were analyzed. | 28676512 |
| palladium, Inflammation, Malnutrition, Anemia | Altered Intercellular Communication | Our findings suggest that anemia is correlated with malnutrition and inflammation in Croatian PD patients. | 28676512 |
| Inflammation, Venous Thrombosis | Altered Intercellular Communication | Age-related diagnostic value of D-dimer testing and the role of inflammation in patients with suspected deep vein thrombosis. | 28676651 |
| Inflammation, Venous Thrombosis | Altered Intercellular Communication | Further research is required to decrypt the role of inflammation in the pathophysiology and diagnosis of venous thrombosis. | 28676651 |
| Inflammation, Obesity | Altered Intercellular Communication | Increased inflammation and oxidative stress associated with obesity can accelerate aging. | 28676678 |
| Degenerative polyarthritis | Altered Intercellular Communication | This study also supported the inflammation-induced DKK1 and OPG in OA pathogenesis. | 28676900 |
| Inflammation, Thrombosis | Altered Intercellular Communication | Recently, the mean platelet volume-to-lymphocyte ratio (MPVLR) has emerged as a novel and readily available marker of inflammation and thrombosis. | 28678144 |
| Inflammation, Atherosclerosis | Altered Intercellular Communication | Neighborhood characteristics influence DNA methylation of genes involved in stress response and inflammation: The Multi-Ethnic Study of Atherosclerosis. | 28678593 |
| group cohesion | Altered Intercellular Communication | Neighborhood social environment, a summary measure of aesthetic quality, safety, and social cohesion, was associated with methylation in 4 of the 7 stress-related genes (AVP, BDNF, FKBP5, SLC6A4) and 7 of the 11 inflammation-related genes (CCL1, CD1D, F8, KLRG1, NLRP12, SLAMF7, TLR1). | 28678593 |
| Pulmonary arterial hypertension, Polycyclic Hydrocarbons, Aromatic | Altered Intercellular Communication | Inflammatory signaling may play an important role in the pathogenesis of pulmonary arterial hypertension (PAH). | 28678692 |
| Inflammation, Non-alcoholic Fatty Liver Disease, Hyperferritinaemia | Altered Intercellular Communication | Hyperferritinaemia in NAFLD is often attributed to inflammation, while in other conditions ferritin closely reflects body iron stores. | 28679028 |
| Crohn Disease | Altered Intercellular Communication | Crohn's disease (CD) is a chronic inflammatory condition of the gastrointestinal tract. | 28679179 |
| Renal Insufficiency, Inflammation, Myalgia, Muscle Fibers | Altered Intercellular Communication | An acute bout of eccentric contractions (ECC) cause muscle fiber damage, inflammation, impaired muscle function (MF) and muscle soreness (MS). | 28680370 |
| Inflammation, Hypertrophy | Altered Intercellular Communication | However, assessment of its therapeutic activity can be challenging because of tumour enlargement associated with intratumoural inflammation. | 28681063 |
| Inflammation | Altered Intercellular Communication | The percentage of cases with PGII >=7.5 mg/L, as indication for antral inflammation, was higher than in controls: 58.6 versus 44.7%, P = 0.027. | 28681188 |
| Gastritis, Abdominal Pain | Altered Intercellular Communication | * Serum pepsinogens (PGs), non-invasive markers of gastric inflammation, were rarely utilized in assessing the association between H. pylori in pediatric abdominal pain of unknown origin. | 28681188 |
| Inflammation, Periodontitis | Altered Intercellular Communication | Platelets contribute to chronic inflammation, but their role in periodontitis is not well understood. | 28681377 |
| Inflammation, Abnormality of the vasculature | Altered Intercellular Communication | A potential contribution of psoriasin to vascular and epithelial abnormalities and inflammation in systemic sclerosis. | 28681537 |
| Inflammation, Sample Size Calculation, Abnormality of the vasculature | Altered Intercellular Communication | Our findings indicate a possible contribution of psoriasin to the development of clinical symptoms associated with vascular and epithelial abnormalities and inflammation in SSc, further supporting the roles of antimicrobial peptides in the SSc pathogenesis. | 28681537 |
| Inflammation, Rheumatism | Altered Intercellular Communication | Detection of synovial inflammation in rheumatic diseases using superb microvascular imaging: Comparison with conventional power Doppler imaging. | 28681656 |
| Refractory anemias, Inflammation, Metacarpophalangeal joint structure | Altered Intercellular Communication | Among the joint regions, the wrists and metacarpophalangeal joints were more sensitive to the detection of synovial inflammation using SMI in patients with RA. | 28681656 |
| Refractory anemias, Inflammation | Altered Intercellular Communication | SMI was more sensitive in detecting synovial inflammation than cPDI in patients with RA. | 28681656 |
| Osteomyelitis, Inflammation, Failure (biologic function) | Altered Intercellular Communication | Background and purpose - Treatment failure of osteomyelitis can result from genetic susceptibility, highlighting polymorphisms of the interleukin-1 (IL-1) family members, central mediators of innate immunity and inflammation. | 28682145 |
| Inflammation, Primary malignant neoplasm | Altered Intercellular Communication | Prognostic Impact of Intra-abdominal/Pelvic Inflammation After Radical Surgery for Locally Recurrent Rectal Cancer. | 28682968 |
| Inflammation, Primary malignant neoplasm | Altered Intercellular Communication | However, it remains unclear whether intra-abdominal/pelvic inflammation after radical surgery for locally recurrent rectal cancer is relevant to its prognosis. | 28682968 |
| Pain Distress Question, Primary malignant neoplasm, Inflammation, Neoplasms | Altered Intercellular Communication | Age (p = 0.002), initial tumor stage (p = 0.03), pain associated with locally recurrent rectal cancer (p = 0.03), CEA level (p = 0.004), resection margin (p < 0.001), intra-abdominal/pelvic inflammation (p < 0.001), and surgery period (p = 0.045) were independent prognostic factors associated with overall survival, whereas CEA level (p = 0.01), resection margin (p = 0.002), and intra-abdominal/pelvic inflammation (p = 0.001) were associated with relapse-free survival. | 28682968 |
| Inflammation, Actual blood loss | Altered Intercellular Communication | A large amount of perioperative blood loss was the only factor associated with the occurrence of intra-abdominal/pelvic inflammation (p = 0.007). | 28682968 |
| Inflammation, Primary malignant neoplasm | Altered Intercellular Communication | Intra-abdominal/pelvic inflammation after radical surgery for locally recurrent rectal cancer is associated with poor prognosis. | 28682968 |
| Fatty Liver, Inflammation, Obesity | Altered Intercellular Communication | The inflammatory kinases IKKe and TBK1 are elevated in obesity; their inhibition in obese mice reduces weight, insulin resistance, fatty liver and inflammation. | 28683283 |
| Communicable Diseases, Inflammation | Altered Intercellular Communication | CD4+ T cells secrete cytokines that promote inflammation and an anti-bacterial response in the gastric mucosa during infection. | 28683359 |
| Inflammation, Infection caused by Helicobacter pylori | Altered Intercellular Communication | The frequencies of IFNg and IL-17A+ cells correlated positively with inflammation in the antrum, but not the corpus, of H. pylori infected individuals. | 28683359 |
| Inflammation, Atherosclerosis | Altered Intercellular Communication | Free arachidonic acid (AA) is an important precursor of lipid mediators such as leukotrienes and prostaglandins that induces inflammation and is associated with atherosclerosis progression. | 28683445 |
| Communicable Diseases, Inflammation | Altered Intercellular Communication | Overall sensitivity was 80.5% and specificity 89.8%, and was not greatly impacted by inflammation or infection. | 28683471 |
| Inflammation, Demographics Domain, Diabetes Mellitus | Altered Intercellular Communication | Recent studies have pointed out a link among RDW, diabetes mellitus (DM) and inflammation. | 28683798 |
| Inflammation, Cachexia | Altered Intercellular Communication | We conclude that FO-enriched nutrition may improve the prognosis of patients with cancer cachexia and systemic inflammation (i.e., those with a mGPS of 1 or 2). | 28684736 |
| Cell Death, Kidney Failure, Acute, Interstitial inflammation, Injury of kidney | Altered Intercellular Communication | Acute kidney injury (AKI) is characterized by tubular cell death and interstitial inflammation. | 28684863 |
| Nasal inflammation | Altered Intercellular Communication | Glycyrrhetinic acid suppressed hmgb1 release by up-regulation of Sirt6 in nasal inflammation. | 28685526 |
| Inflammation, Chronic Fatigue Syndrome | Altered Intercellular Communication | This study elucidates the question of whether chronic inflammation in the jawbone contributes to the development of Chronic Fatigue Syndrome (CFS). | 28685531 |
| Inflammation, Chronic Fatigue Syndrome | Altered Intercellular Communication | Constituting a hidden source of silent inflammation FDOJ may represent a hitherto unknown cause for the development of CFS. | 28685531 |
| Inflammation, Non-Small Cell Lung Carcinoma | Altered Intercellular Communication | Our exploratory analysis showed markers of systemic inflammation predicted survival outcomes in advanced NSCLC. | 28685599 |
| Inflammation | Altered Intercellular Communication | Carriers of the risky genotype or haplotype also had increased gastric OPN expression (p = 0.038) and inflammation (p = 0.007). | 28685609 |
| Chronic lymphocytic inflammation, Pontine structure, Clippers | Altered Intercellular Communication | Introduction Chronic lymphocytic inflammation with pontine perivascular enhancement responsive to steroids (CLIPPERS) is an inflammatory central nervous system (CNS) disorder with particular involvement of the pons. | 28685649 |
| Inflammation, Amyloidosis | Altered Intercellular Communication | Systemic AA amyloidosis is a serious complication of chronic inflammation; however, there are relatively few published data on its incidence. | 28686088 |
| Communicable Diseases, Periodontitis, Inflammation | Altered Intercellular Communication | Infection and apoptosis associated with inflammation in periodontitis: An immunohistologic study. | 28686335 |
| Hypertrophy, Tubular atrophy, Interstitial Fibrosis Assessment, Interstitial inflammation | Altered Intercellular Communication | Histopathologically, glomerular enlargement, interstitial fibrosis, tubular atrophy, interstitial inflammation and global amyloid deposition were significantly associated with lower estimated glomerular filtration rate (eGFR) (p = .02, p < .001, p = .001, p = .009, p = .002, respectively) in univariate analysis. | 28686525 |
| Pain Distress Question, Arthritis, Inflammation, Neuralgia | Altered Intercellular Communication | The objectives were to quantify and characterize pain phenotypes (non-neuropathic vs. neuropathic features) among Danish arthritis patients using the PDQ, and to assess the association with on-going inflammation. | 28686639 |
| Pain Distress Question, Inflammation | Altered Intercellular Communication | PDQ-score was associated with DAS28-CRP and VAS pain but not with indicators of peripheral inflammation (CRP and SJC). | 28686639 |
| Inflammation | Altered Intercellular Communication | Coronary artery disease-associated genetic variants and biomarkers of inflammation. | 28686695 |
| Inflammation, Coronary Artery Disease | Altered Intercellular Communication | Genetic constitution and inflammation both contribute to development of coronary artery disease (CAD). | 28686695 |
| Vasculitis, Leukocytoclastic, Cutaneous, Inflammation, Petechiae, Purpura | Altered Intercellular Communication | Leukocytoclastic vasculitis (LCV) is a disease characterized by inflammation of small vessels presenting with petechiae and palpable purpura. | 28686752 |
| Inflammation, Noncommunicable Diseases | Altered Intercellular Communication | The association between total phthalate concentration and non-communicable diseases and chronic inflammation in South Australian urban dwelling men. | 28686951 |
| Inflammation, Noncommunicable Diseases | Altered Intercellular Communication | To investigate associations between urinary total phthalate concentration, chronic low-grade inflammation and non-communicable diseases in a cohort of South Australian men. | 28686951 |
| Inflammation, Chronic disease | Altered Intercellular Communication | Multivariable linear and logistic regression models were applied to determine associations of log-transformed urinary phthalate concentration with inflammation and chronic disease. | 28686951 |
| Inflammation, Chronic pain syndrome | Altered Intercellular Communication | Fibromyalgia, a potentially debilitating chronic pain syndrome of unknown etiology, may be characterized by inflammation. | 28687081 |
| Respiratory Distress Syndrome, Adult, Inflammation, Surfactant Dysfunction, Lung Volume Measurements, Respiration Disorders | Altered Intercellular Communication | We also provide expert consensus that mechanisms causing ARDS in adults and older children-namely complex surfactant dysfunction, lung tissue inflammation, loss of lung volume, increased shunt, and diffuse alveolar damage-are also present in several critical neonatal respiratory disorders. | 28687343 |
| Kidney Failure, Hypopituitarism | Altered Intercellular Communication | Failure of pituitary gland identification presented with hormonal insufficiency of 46.2%. | 28687446 |
| HIV Antigens, HIV Infections, Cardiovascular Diseases | Altered Intercellular Communication | To explore the link between HIV infection and cardiovascular diseases, we used postmortem human heart tissues obtained from HIV-infected and control uninfected individuals to examine connexin 43 (Cx43) expression and distribution and HIV-associated inflammation. | 28688235 |
| Cataract, Inflammation, Hypopyon | Altered Intercellular Communication | A 57-year-old female underwent cataract surgery and developed hypopyon on day 3 after surgery, with mainly anterior chamber inflammation. | 28689242 |
| Inflammation, Atherosclerosis | Altered Intercellular Communication | The high-WHtR group (>=0.5) showed greater morbidity and increased inflammation in association with atherosclerosis compared with the low-WHtR group. | 28690284 |
| Inflammation, Cerebrovascular accident | Altered Intercellular Communication | Vinpocetine Inhibits NF-kB-Dependent Inflammation in Acute Ischemic Stroke Patients. | 28691141 |
| Inflammation, Ischemic stroke | Altered Intercellular Communication | Immunity and inflammation play critical roles in the pathogenesis of acute ischemic stroke. | 28691141 |
| Inflammation | Altered Intercellular Communication | These effects led to significantly reduced secondary lesion enlargement and an attenuated inflammation reaction. | 28691141 |
| Inflammation, Ischemic stroke | Altered Intercellular Communication | These findings identify vinpocetine as an inflammation modulator that could improve clinical outcomes after acute ischemic stroke. | 28691141 |
| Inflammation, Ischemic stroke | Altered Intercellular Communication | This study also indicated the important role of immunity and inflammation in the pathogenesis of acute ischemic stroke and the significance of immunomodulatory treatment. | 28691141 |
| Inflammation, Irritation | Altered Intercellular Communication | Oral mucosa is constantly under the influence of various internal and external stimuli, therefore it is interested by a range of developmental disorders, irritation, inflammation, and neoplastic conditions. | 28691450 |
| Inflammation | Altered Intercellular Communication | It is argued that there are no modifiable factors such as age, or genetic factors, but that there are other factors that could be avoided, modified or controlled such as periodontal peripheral inflammation. | 28691472 |
| Inflammation | Altered Intercellular Communication | We conducted repeated measurements of lung function and inflammation biomarker in a cohort consisted of 60 participants with T2DM. | 28692015 |
| ARCN1 gene, Inflammation, Chronic Obstructive Airway Disease | Altered Intercellular Communication | Chronic inflammation and remodelling of the small airways are features related to chronic obstructive pulmonary disease (COPD). | 28692348 |
| Inflammation | Altered Intercellular Communication | Chronic HIV-1 infection leads to widespread inflammation and immune dysregulation. | 28692540 |
| Communicable Diseases, Inflammation | Altered Intercellular Communication | Both miRs de-repress the IL-6/STAT3 signaling pathway, which could contribute to increased inflammation during infection. | 28692540 |
| Inflammation | Altered Intercellular Communication | Cryopyrin-associated periodic syndromes (CAPS) result from gain-of-function mutations in the NLRP3 gene, which causes excessive release of interleukin-1b (IL-1b) and systemic inflammation. | 28692792 |
| Inflammation | Altered Intercellular Communication | Clinical presentation and CAPS markers of inflammation were captured. | 28692792 |
| Inflammation, Impaired cognition, Mental disorders | Altered Intercellular Communication | Elevated C-reactive protein (CRP), a non-specific biomarker of systemic bodily inflammation, has been associated with more pronounced cognitive impairments in adults with psychiatric disorders, particularly in the domains of memory and executive function. | 28694011 |
| Inflammation, Damage | Altered Intercellular Communication | Young age, complicated disease, and persistent inflammation were associated with bowel damage. | 28694130 |
| Inflammation, Dysplasia, Primary malignant neoplasm, Neoplasms, Adenocarcinoma of small intestine | Altered Intercellular Communication | Assessment of surgical specimens of small bowel adenocarcinomas revealed a clear transition from inflammation to dysplasia and cancer, whereas no tumors had evidence of microsatellite instability. | 28694132 |
| Adenocarcinoma, Adenocarcinoma of large intestine | Altered Intercellular Communication | Adenocarcinomas appeared to develop via an inflammation-dysplasia-carcinoma pathway, but differed from IBD-related colorectal adenocarcinomas in their molecular features. | 28694132 |
| Inflammation, pathologic fistula, With intensity | Altered Intercellular Communication | Among the 26 patients in clinical remission, 10 had persisting inflammation of fistulas on MRI (T2 hyperintensity, n = 7; contrast enhancement, n = 10). | 28694669 |
| ARCN1 gene, Asthma-Chronic Obstructive Pulmonary Disease Overlap Syndrome, Chronic Obstructive Airway Disease, Inflammatory disorder, Asthma | Altered Intercellular Communication | A new phenotype with overlapping characteristics between asthma and chronic obstructive pulmonary disease (COPD) called asthma-COPD overlap syndrome (ACOS) is emerging among inflammation diseases. | 28694694 |
| Inflammation, Obesity, HIV Infections | Altered Intercellular Communication | We hypothesized inflammation increases when obesity and HIV infection co-occur. | 28696344 |
| Inflammation, Osteoporosis, Obesity | Altered Intercellular Communication | The excessive fat accumulation, local and systemic inflammation may lead to dysregulation in immune function and relevant health problems, including obesity and osteoporosis. | 28696349 |
| Inflammation | Altered Intercellular Communication | It results from synovial inflammation and direct cartilage-degenerating properties of blood components. | 28696534 |
| Inflammation, Hemarthrosis, Cartilage damage | Altered Intercellular Communication | In contrast, equimolar amounts of the fusion protein attenuated cartilage damage upon repeated joint bleeding, although synovial inflammation was hardly affected. | 28696534 |
| Inflammation, Non-alcoholic Fatty Liver Disease, Diabetes Mellitus, Non-Insulin-Dependent | Altered Intercellular Communication | Type 2 diabetes patients with NAFLD had a higher prevalence of PAD, and this association was partly, but not entirely, explained by metabolic risk factors and inflammation. | 28696562 |
| Inflammation, Fatty degeneration | Altered Intercellular Communication | Increased key BAs were associated with higher grades of steatosis (taurocholate), lobular (glycocholate) and portal inflammation (taurolithocholate), and hepatocyte ballooning (taurocholate). | 28696585 |
| Airway structure, Asthma | Altered Intercellular Communication | Sputum eosinophil, being a marker of airway inflammation, can serve as a tool for assessing severity and response to treatment in asthma patients. | 28696802 |
| Autoimmune Diseases, Inflammation | Altered Intercellular Communication | Tissue inhibitor of metalloproteinase-1 (TIMP-1) is a protein implicated in the control of inflammation in a number of autoimmune diseases. | 28696822 |
| Neoplasms | Altered Intercellular Communication | Inflammation was the most common cause of false positives and small tumor volume and low 18F-FDG avidity were the causes of false negatives. | 28697190 |
| Fever, CTCAE | Altered Intercellular Communication | Six weeks later, the patient developed high fever again and in order to revaluate the periprosthetic inflammation, he was resubmitted to 18F-FDG PET/CT which showed normal 18F-FDG uptake in the whole skeleton, including the prosthesis and the subcutaneous wound. | 28697197 |
| Anxiety, CTCAE 3.0, Mood Disorders, Depression, CTCAE, Inflammation | Altered Intercellular Communication | Depression and anxiety are two common mood disorders that are both linked to systemic inflammation. | 28697416 |
| Inflammation, "Alzheimers Disease | Altered Intercellular Communication | The Relationship between Markers of Inflammation and Degeneration in the Central Nervous System and the Blood-Brain Barrier Impairment in Alzheimer's Disease. | 28697565 |
| Inflammation, Cerebral Hemorrhage | Altered Intercellular Communication | Although preclinical studies have shown inflammation to mediate perihematomal edema (PHE) after intracerebral hemorrhage, clinical data are lacking. | 28698256 |
| Inflammation, Pain Distress Question | Altered Intercellular Communication | Cold treatments are used to relieve joint inflammation and pain. | 28698947 |
| Bone Diseases, Inflammation, Chronic kidney disease mineral and bone disorder | Altered Intercellular Communication | Epidemiologic studies have suggested a link between chronic systemic inflammation and chronic kidney disease-mineral and bone disorder (CKD-MBD). | 28699886 |
| Chronic kidney disease mineral and bone disorder, Inflammation | Altered Intercellular Communication | Additionally, declining renal function is associated with worsening physical and cognitive function, which may potentially be explained by systemic inflammation, CKD-MBD, or both. | 28699886 |
| Chronic kidney disease mineral and bone disorder, Inflammation, Chronic Kidney Diseases | Altered Intercellular Communication | We hypothesized that inhibiting inflammation with an interleukin-1 (IL-1) trap would improve markers of CKD-MBD as well as physical/cognitive function in patients with moderate-to-severe CKD. | 28699886 |
| Inflammatory Bowel Diseases, Inflammation, Anemia | Altered Intercellular Communication | We aimed to investigate the association of vitamin D status with inflammation, iron biomarkers, and anemia in pediatric IBD. | 28700535 |
| Inflammation, hepcidin, Anemia | Altered Intercellular Communication | Multivariable logistic/linear models were used to examine the associations of 25(OH)D with inflammation, iron status, hepcidin, and anemia. | 28700535 |
| Anemia | Altered Intercellular Communication | Iron deficiency prevalence (inflammation-corrected ferritin <15 mg/L or soluble transferrin receptor >8.3 mg/L) was 67%; anemia was 36%, and vitamin D insufficiency (25(OH)D <30 ng/mL) was 77%. | 28700535 |
| Inflammation, selenium, Ulcerative Colitis, Crohn Disease | Altered Intercellular Communication | In linear regression models, vitamin D insufficiency was associated with increased hepcidin levels (b [SE] = 0.6 [0.2], P = 0.01) and reduced hemoglobin (b [SE] = -0.9 [0.5], P = 0.046), controlling for age, sex, race, insurance status, body mass index for age, inflammation, disease diagnosis (ulcerative colitis versus Crohn's disease), and disease duration, compared with 25(OH)D >=30 ng/mL. | 28700535 |
| Inflammatory Bowel Diseases, Inflammation, Anemia | Altered Intercellular Communication | Further research is needed to clarify the association of vitamin D with inflammation, iron status, and anemia in pediatric IBD. | 28700535 |
| Kidney Failure, Chronic, Inflammation | Altered Intercellular Communication | Most ESRD patients have systemic inflammation, and increasing the risk of cardiovascular event. | 28701158 |
| Inflammation, Sarcopenia | Altered Intercellular Communication | The emergence of sarcopenia was accompanied by increased levels of inflammation factors TNF-a and IL-6. | 28701179 |
| Inflammation | Altered Intercellular Communication | Future studies should determine whether increasing life satisfaction and positive affect may contribute to improvements in health behaviors, inflammation, and better health outcomes. | 28701268 |
| Inflammation, destruction joint, Chronic arthritis | Altered Intercellular Communication | Synovial fibroblasts (SF) drive inflammation and joint destruction in chronic arthritis. | 28701277 |
| Inflammation, Fibrosis Assessment, Idiopathic Pulmonary Fibrosis | Altered Intercellular Communication | Extracellular accumulation of adenosine and subsequent activation of the ADORA2B receptor play important roles in regulating inflammation and fibrosis in IPF. | 28701304 |
| Inflammation, Demyelination, Degenerative brain disorder, CNS disorder | Altered Intercellular Communication | Multiple sclerosis (MS) is a pathologically complex CNS disease: inflammation, demyelination, and neuroaxonal degeneration occur concurrently and may depend on one another. | 28702353 |
| Gastroesophageal reflux disease, Chronic Obstructive Airway Disease, Gorontalo Language, Asthma | Altered Intercellular Communication | Gastroesophageal reflux disease (GORD) is well known to initiate or exacerbate pulmonary inflammatory conditions, inducing bronchial asthma and chronic obstructive lung disease. | 28702854 |
| Inflammation, Ulceration, CTCAE | Altered Intercellular Communication | Barium oesophagography, gastroesophageal endoscopy, and biopsy suggested oesophageal-related chronic inflammation and ulceration, which may have caused the repeated oesophagobronchial fistulas. | 28703631 |
| Obesity, Diabetes Mellitus | Altered Intercellular Communication | Association between Type 2 Diabetes, Obesity and Key Immunological Components of IgE-mediated Inflammation. | 28704195 |
| Immediate hypersensitivity, square decimeter, Obesity | Altered Intercellular Communication | The link between obesity and DM2 with immunological components of IgE-mediated allergic inflammation is not yet conclusively established. | 28704195 |
| Immediate hypersensitivity, square decimeter | Altered Intercellular Communication | To examine the key immunological components of IgE-mediated allergic inflammation in patients with DM2 and their relationship with glycemic control and anthropometric indicators. | 28704195 |
| Immediate hypersensitivity, square decimeter, Obesity | Altered Intercellular Communication | Obesity and poor glycemic control in patients with DM2 affect key immunological components of IgE-mediated allergic inflammation and possibly alter the immune response to allergens and antigens. | 28704195 |
| Inflammation, Metabolic Diseases, Cardiovascular Diseases | Altered Intercellular Communication | Mitochondrial DNA (mtDNA) content might undergo significant changes caused by metabolic derangements, oxidative stress and inflammation that lead to development and progression of cardiovascular diseases. | 28704533 |
| Liver carcinoma, Hepatitis, Fibrosis Assessment, Inflammatory, Hepatobiliary Disorder, FAM126A gene, Carcinogenic Chlorinated Hydrocarbon, Liver Cirrhosis | Altered Intercellular Communication | Interferon-related genetic markers of necroinflammatory activity in chronic hepatitis C. Chronic hepatitis C (CHC) is a major cause of liver disease worldwide which often leads to progressive liver inflammation, fibrosis, cirrhosis and hepatocellular carcinoma (HCC). | 28704535 |
| Inflammation, Malnutrition | Altered Intercellular Communication | Multivariable adjustments were done for case-mix and markers of the malnutrition, and inflammation complex and intravenous iron dose. | 28704813 |
| Inflammation, Neoplasms, Esophageal carcinoma | Altered Intercellular Communication | Hamburg-Glasgow classification: preoperative staging by combination of disseminated tumour load and systemic inflammation in oesophageal carcinoma. | 28704837 |
| Inflammation, Neoplasms | Altered Intercellular Communication | Systemic inflammation and disseminated tumour load have a pivotal role in recurrence and oncological outcome. | 28704837 |
| Communicable Diseases, Inflammation | Altered Intercellular Communication | Infection and inflammation were associated with low levels of all long-chain (LC)-PUFAs, while hemoglobin was positively associated with whole-blood LC-PUFAs. | 28705254 |
| Communicable Diseases, Inflammation | Altered Intercellular Communication | Infection, inflammation, hemoglobin, anthropometry and diet were correlates of PUFAs concentrations in children with MAM. | 28705254 |
| Inflammation, East Frisian Low Saxon Language, Cyclophosphamide/Vincristine/Dacarbazine Regimen, Cardiovascular Diseases | Altered Intercellular Communication | Chronic inflammation is an independent risk factor for cardiovascular disease (CVD), but most risk calculators, including the Framingham risk score (FRS) and the American College of Cardiology (ACC)/American Heart Association (AHA) risk score do not account for it. | 28705378 |
| Airway structure | Altered Intercellular Communication | Recent evidence has suggested that the innate immune response may play a role in the development of eosinophilic airway inflammation. | 28705588 |
| Airway structure | Altered Intercellular Communication | We previously reported that uric acid (UA) and adenosine triphosphate (ATP), two important damage-associated molecular pattern molecules (DAMPs), activate eosinophil functions, suggesting that these molecules may be involved in the development of eosinophilic airway inflammation. | 28705588 |
| Degenerative polyarthritis, Inflammation, Bone Marrow | Altered Intercellular Communication | Microarray analysis of bone marrow lesions in osteoarthritis demonstrates upregulation of genes implicated in osteochondral turnover, neurogenesis and inflammation. | 28705915 |
| Sarcoidosis | Altered Intercellular Communication | Genes comprising the composite gene expression score, TCR factor, may represent a blood-derived measure of T-cell activity and an indirect measure of active sarcoidosis inflammation. | 28707108 |
| Inflammation, Obesity | Altered Intercellular Communication | Immunosenescence Induced by Plasma from Individuals with Obesity Caused Cell Signaling Dysfunction and Inflammation. | 28707376 |
| Inflammation, Immunosenescence, Obesity | Altered Intercellular Communication | These results demonstrate that chronic systemic inflammation observed in obesity induces dysfunctional features in PBMC that are consistent with premature immunosenescence. | 28707376 |
| Inflammation | Altered Intercellular Communication | Histopathologic diagnosis revealed 42% (teeth = 8) without periapical inflammation, 16% (teeth = 3) with mild inflammation and 42% (teeth = 8) with moderate to intense inflammation. | 28707526 |
| Inflammation, Plasmodium falciparum infection | Altered Intercellular Communication | The prevalence of Plasmodium falciparum infection and inflammation during the study were 44-66%, and 57-76%, respectively. | 28708072 |
| Injury of cornea, Inflammatory abnormality of the eye | Altered Intercellular Communication | The double-masked phase demonstrated that CsA CE was effective in reducing corneal damage and ocular surface inflammation, and was well-tolerated over 6 months. | 28708219 |
| AATF wt Allele, Keratitis, Inflammatory abnormality of the eye | Altered Intercellular Communication | In this 12-month study, once-daily CsA CE was well-tolerated and showed reductions in ocular surface inflammation and improvements in signs/symptoms in DED patients with severe keratitis. | 28708219 |
| Inflammation, Ulcerative Colitis | Altered Intercellular Communication | A local imbalance between regulatory (Treg) and effector T cells is believed to play a major role in gut-specific inflammation, including ulcerative colitis (UC). | 28708802 |
| Chronic Obstructive Airway Disease, asthma with copd | Altered Intercellular Communication | Neutrophilic inflammation is common in chronic obstructive pulmonary disease while Asthma COPD overlap syndrome has eosinophilic predominance. | 28709489 |
| ARCN1 gene, Inflammation, Asthma | Altered Intercellular Communication | Identifying the type of inflammation will aid in better management of COPD, but published studies show that induced sputum examination is more frequently used in asthma than COPD, with safety being the limiting factor. | 28709489 |
| Granulomatous inflammation, Cryptococcus | Altered Intercellular Communication | Diagnostic thoracoscopic wedge resection of the right lung nodule revealed granulomatous inflammation with cryptococcus on histopathology. | 28709495 |
| Inflammation, Atrophic | Altered Intercellular Communication | Atrophy (P = 0.001; P<0.01) and chronic inflammation grade (P = 0.026; P<0.05) were significantly higher in Staple Line Leak patients. | 28709560 |
| Refractory anemias, Inflammation, GDC AJCC Clinical Stage Terminology | Altered Intercellular Communication | ACS in RA has been linked to inflammation and RA severity. | 28710095 |
| Inflammation, Albuminuria, Cardiovascular morbidity | Altered Intercellular Communication | Albuminuria is a marker of inflammation and an independent predictor of cardiovascular morbidity and mortality. | 28710178 |
| Communicable Diseases, Inflammation, Pericardial Effusion, CTCAE, Pericarditis, Constrictive | Altered Intercellular Communication | Constrictive pericarditis secondary to endocardial pacemaker inflammation, without associated pericardial effusion or infection, has yet to be described in the literature. | 28710300 |
| Inflammation, Neoplasms | Altered Intercellular Communication | In conclusion, low serum APOA1 levels are associated with advanced stage and systemic inflammation, while serum APOB does not significantly correlate with tumor stage. | 28710487 |
| Inflammation, Thrombosis, palladium, Fibrosis Assessment, Cardiac complication | Altered Intercellular Communication | Aldosterone antagonist therapy and its relationship with inflammation, fibrosis, thrombosis, mineral-bone disorder and cardiovascular complications in peritoneal dialysis (PD) patients. | 28710615 |
| Degenerative polyarthritis, Inflammation, Synovial Fluid | Altered Intercellular Communication | Interestingly, OA affecting the synovial facet joint was associated with a marker of inflammation (HA). | 28711584 |
| Impaired cognition | Altered Intercellular Communication | Using a high-fat diet (HFD) consumption-induced obese mouse model, we tested our hypothesis that recombinant human FGF21 (rFGF21) administration is effective for improving obesity-induced cognitive dysfunction and anxiety-like behavior, by its multiple metabolic modulation and anti-pro-inflammation actions. | 28712011 |
| Hyperlipidemia, Impaired cognition, Hippocampus (Brain), Glucose Intolerance (disease), Neurogenesis | Altered Intercellular Communication | Our experimental findings support our hypothesis that rFGF21 is protective to HFD-induced cognitive impairment, at least in part by metabolic regulation in glucose tolerance impairment, insulin resistance, and hyperlipidemia; potent systemic pro-inflammation inhibition; and improvement of hippocampal dysfunction, particularly by inhibiting pro-neuroinflammation and neurogenesis deficit. | 28712011 |
| Inflammation, Eosinophilic esophagitis, Esophageal Diseases, "Extra-osseous Ewings sarcoma | Altered Intercellular Communication | Eosinophilic esophagitis (EoE) is a chronic, immune/antigen-mediated disease characterized by symptoms related to esophageal dysfunction and an eosinophil-predominant inflammation. | 28712126 |
| Pancreatic duct calculus, Pancreatitis | Altered Intercellular Communication | Acute pancreatitis is an inflammatory condition of pancreas, when, associated with pancreatic duct stones a lateral pancreaticojejunostomy is done, which, results in better outcomes decreasing the mortality and morbidity. | 28712198 |
| Inflammation, Non-Small Cell Lung Carcinoma, Depression, CTCAE | Altered Intercellular Communication | Depression, inflammation, and epidermal growth factor receptor (EGFR) status in metastatic non-small cell lung cancer: A pilot study. | 28712427 |
| Inflammation, Thrombocytosis, Atherosclerosis | Altered Intercellular Communication | Thrombocytosis and inflammation are vital elements in the pathogenesis of atherosclerosis. | 28712557 |
| Inflammatory abnormality of the eye, Uveitis | Altered Intercellular Communication | After two failed bevacizumab intravitreal injections, uveitis responded to systemic adalimumab administration, with a complete and long-term remission of ocular inflammation. | 28713058 |
| Inflammation, Inflammatory disease of mucous membrane | Altered Intercellular Communication | CCE-2 had a sensitivity of 97% and 94% to detect mucosal inflammation (MES >0) and moderate to severe inflammation (MES >1), respectively. | 28713062 |
| Inflammation, Hemorrhage, Superficial ulcer | Altered Intercellular Communication | In per-segment analysis, the negative predictive values of CCE-2 to detect mucosal inflammation, including vascular pattern loss, bleeding, and erosions reached 94% to 95%. | 28713062 |
| Inflammation, Diabetes Mellitus, Non-Insulin-Dependent, Chronic disease | Altered Intercellular Communication | Type 2 diabetes (T2D) is an age-related chronic disease associated with metabolic dysregulation, chronic inflammation, and activation of peripheral blood mononuclear cells (PBMC). | 28713486 |
| Communicable Diseases, Inflammation, Diabetes Mellitus | Altered Intercellular Communication | Infection and inflammation were associated with mortality in individuals both with and without diabetes. | 28713837 |
| Temporomandibular Joint Disorders, Inflammation, Synovitis | Altered Intercellular Communication | TMD is frequently associated with synovitis, a chronic inflammation of the synovium. | 28714016 |
| Inflammation | Altered Intercellular Communication | These findings suggest a model for inflammation in the TMJ where EDPs are generated by harmful mechanical stimuli, induce both a pro-inflammatory cascade and increase expression of MMP-12 through activation of the EBP signalling cascade. | 28714016 |
| Inflammation | Altered Intercellular Communication | This may lead to further increases in EDP levels, establishing a positive feedback loop leading to chronic inflammation in the TMJ. | 28714016 |
| palladium, Inflammation, HD Term Type, Atherosclerosis | Altered Intercellular Communication | We evaluated the association between residual renal function (RRF), phosphate level, inflammation and other risk factors in carotid modeling as a marker of early atherosclerosis in peritoneal dialysis (PD) compared with hemodialysis (HD) patients. | 28714271 |
| Inflammation, Arthritis | Altered Intercellular Communication | While the cytokine and cellular pathways triggering arthritis are well defined, those responsible for the resolution of inflammation are incompletely characterized. | 28714991 |
| Inflammation | Altered Intercellular Communication | Here we identified interleukin (IL)-9-producing type 2 innate lymphoid cells (ILC2s) as the mediators of a molecular and cellular pathway that orchestrates the resolution of chronic inflammation. | 28714991 |
| Inflammation | Altered Intercellular Communication | Hence, fostering IL-9-mediated ILC2 activation may offer a novel therapeutic approach inducing resolution of inflammation rather than suppression of inflammatory responses. | 28714991 |
| Inflammation | Altered Intercellular Communication | Following each surgery, the emphasis was on decreasing inflammation and maintaining patellar mobility while increasing joint range of motion and strength. | 28715241 |
| Inflammation, Anxiety Disorders, Bipolar Disorder | Altered Intercellular Communication | T. gondii seropositivity is associated with generalized anxiety disorder, depressive symptoms and comorbid depressive and anxiety disorders, which is not mediated by inflammation. | 28715724 |
| Inflammation, Autoimmune Diseases, Fibrosis Assessment, Sample Size Calculation, Abnormality of the vasculature | Altered Intercellular Communication | Systemic sclerosis (SSc) is an autoimmune disease characterized by microvascular abnormalities, inflammation and fibrosis. | 28716007 |
| Hormone abnormality, Alopecia | Altered Intercellular Communication | Distribution of hair loss and associated hormonal abnormalities aid in the recognition of FFA in men. | 28716436 |
| Compression injury of nerve, Optic Neuritis | Altered Intercellular Communication | Two main hypotheses have been proposed for the pathophysiology of long thoracic nerve (LTN) palsy: nerve compression and nerve inflammation. | 28716694 |
| Inflammation, Neoplasms | Altered Intercellular Communication | Per-operative freeze-microscopy showed inflammation tissue, whereas subsequent microscopy showed papillary-cystic endolymphatic sac tumor. | 28716765 |
| Inflammation, Takayasu Arteritis, Aortitis, Arteritis | Altered Intercellular Communication | There are a few published cases of diffuse aortitis and aorta collaterals inflammation that fulfill Takayasu's arteritis (TA) criteria coexisting with AS. | 28718336 |
| Refractory Cytopenia of Childhood, Inflammation, Renal Cell Carcinoma Pathway | Altered Intercellular Communication | The relation between diet-related inflammation and renal cell carcinoma (RCC) has not been investigated. | 28718670 |
| Inflammation, Demyelination | Altered Intercellular Communication | The extent and distribution of fibrin(ogen) was assessed and related to measures of demyelination, inflammation, and neuronal density. | 28719020 |
| Presenile dementia, Inflammation, Primary malignant neoplasm, Immune System Diseases | Altered Intercellular Communication | Although chronic inflammation and immune disorders are of great importance to the pathogenesis of both dementia and cancer, the pathophysiological mechanisms are not clearly understood. | 28719625 |
| Inflammation, Obesity | Altered Intercellular Communication | Thus, results of this study indicate that WHtR is a simple and effective anthropometric variable that has the potential to identify central obesity and the associated inflammation even in women with normal BMI. | 28719789 |
| Alzheimers Disease", Inflammation, Data types - Address | Altered Intercellular Communication | In Alzheimer disease (AD) inflammation becomes evident throughout the course of the disease. | 28719891 |
| Inflammation, Impaired cognition | Altered Intercellular Communication | However, the association between inflammation, cognitive impairment, and cerebrospinal biomarkers (Ab42, t-tau, p-tau181, and Ab42/p-tau181 ratio) is poorly understood. | 28719891 |
| Inflammation, Opisthorchis viverrini Infection, Cholangiocarcinoma, Fibrosis Assessment, FBN2 wt Allele | Altered Intercellular Communication | Opisthorchis viverrini infection induces chronic inflammation, and a minor proportion of infected individuals develop advanced periductal fibrosis (APF) and cholangiocarcinoma (CCA). | 28719954 |
| Down Syndrome, "Alzheimers Disease", Inflammation Mediators, Data types - Address | Altered Intercellular Communication | We hypothesized that an inflammation-mediated dysregulation of these miRNAs may occur in patients with Down syndrome (DS) and Alzheimer's disease (AD). | 28720071 |
| Neoplasms | Altered Intercellular Communication | These symptoms may occur because of changes in neurotransmitter secretion caused by tumors. | 28720269 |
| Aneurysm, Rupture | Altered Intercellular Communication | Aortic Wall Inflammation Predicts Abdominal Aortic Aneurysm Expansion, Rupture, and Need for Surgical Repair. | 28720724 |
| Inflammation, Aortic Aneurysm, Abdominal, Aneurysm | Altered Intercellular Communication | USPIO-enhanced MRI is a novel approach to the identification of aortic wall cellular inflammation in patients with abdominal aortic aneurysms and predicts the rate of aneurysm growth and clinical outcome. | 28720724 |
| Inflammation, Ischemic stroke | Altered Intercellular Communication | Increased monocyte count associated with HARM supports importance of systemic inflammation in BBB disruption in acute ischemic stroke. | 28722240 |
| Inferior vena cava structure, Inflammation, Thrombosis, Compression | Altered Intercellular Communication | Hepatic vein and inferior vena cava (IVC) thrombosis are rare but well-documented complications of ALA, typically attributed to mechanical compression and inflammation associated with a large abscess. | 28722597 |
| Inflammation, Dysplasia, Gastritis, Malignant Neoplasms, Goblet Cells | Altered Intercellular Communication | Moderate chronic gastritis with lymphoid aggregates and slight acute inflammation were noticed, whereas no malignancy, dysplasia, or goblet cell metaplasia was detected. | 28723278 |
| Weight Gain, Inflammation | Altered Intercellular Communication | NF-kB p65 serine 467 phosphorylation sensitizes mice to weight gain and TNFa-or diet-induced inflammation. | 28723419 |
| Hepatitis | Altered Intercellular Communication | Although glucose metabolism or insulin sensitivity was not improved, diet-induced liver inflammation was diminished in S467A mice. | 28723419 |
| Sarcoidosis, Tuberculosis | Altered Intercellular Communication | However, F-18 FDG can also exhibit intense accumulation in tissues in inflammatory conditions such as active tuberculosis (TB) and sarcoidosis. | 28723740 |
| Inflammation | Altered Intercellular Communication | An obstructed chest tube, leaving unevacuated blood around the heart and lungs, can lead to atrial inflammation, which can trigger POAF. | 28724233 |
| Osteomyelitis, Granulomatous inflammation, Vasculitis, CTCAE, Pseudomonas aeruginosa | Altered Intercellular Communication | Biopsy of the skull base/clivus revealed necrotising granulomatous inflammation with focal vasculitis consistent with GPA, and multiple bone cultures were positive for Pseudomonas aeruginosa This patient was diagnosed concurrently with GPA and P. aeruginosa skull base osteomyelitis. | 28724596 |
| Cessation of life, Inflammation, Calcinosis | Altered Intercellular Communication | A minority of veins expressed markers of inflammation, cell proliferation, cell death, calcification, or neoangiogenesis. | 28724774 |
| Sepsis, Inflammation | Altered Intercellular Communication | These findings demonstrate that anti-HMGB1 antibodies alter inflammation in murine sepsis models and reduce sepsis mortality without potentiating immunosuppression. | 28724977 |
| Inflammation, Gastritis, Bacterial Infections, Malignant neoplasm of stomach | Altered Intercellular Communication | Helicobacter pylori is responsible for 70% of gastric cancers globally, and patients with this bacterial infection often present with early stages of the carcinogenic pathway such as inflammation or gastritis. | 28725964 |
| Inflammation, Primary malignant neoplasm | Altered Intercellular Communication | Other studies have shown the relationship between high vagus nerve activity and survival in cancer patients via reduced levels of inflammation, indicating the essential role of the vagus nerve. | 28726018 |
| Diabetic Nephropathy, Inflammation, Metabolic Diseases, Diabetes Mellitus | Altered Intercellular Communication | Diabetic nephropathy (DN) is one of the most lethal complications of diabetes mellitus with metabolic disorders and chronic inflammation. | 28726774 |
| Diabetic Retinopathy, Cardiac complication, Inflammation, GDC Disease Response Terminology | Altered Intercellular Communication | Diabetic retinopathy (DR) is a well-known microvascular complication related to inflammation. | 28726778 |
| Inflammation | Altered Intercellular Communication | FOXQ1 regulates senescence-associated inflammation via activation of SIRT1 expression. | 28726780 |
| Inflammation, Frontal fibrosing alopecia | Altered Intercellular Communication | Thermal imaging and dermoscopy for detecting inflammation in frontal fibrosing alopecia. | 28727235 |
| Frontal fibrosing alopecia, Nonesterified Fatty Acids | Altered Intercellular Communication | Frontal fibrosing alopecia (FFA) is an inflammatory condition of the scalp, which leads to scarring and slowly progressive recession of frontotemporal and/or frontoparietal hairline. | 28727235 |
| Herpes zoster disease, Hertz (Hz), Postherpetic neuralgia, Inflammation | Altered Intercellular Communication | Herpes zoster (HZ) is associated with inflammation of the peripheral nerves, which is considered to be an important cause of postherpetic neuralgia (PHN). | 28727702 |
| Inflammation, Chronic sinusitis, Craniosynostosis, Inflammatory disorder | Altered Intercellular Communication | Chronic rhinosinusitis (CRS) is a common inflammatory disorder of the upper airway characterized by chronic inflammation and significant sinonasal remodeling. | 28727907 |
| Inflammation, Cystitis | Altered Intercellular Communication | Xanthogranulomatous cystitis (XC) is a rare condition affecting the bladder thought to be caused by chronic inflammation. | 28727973 |
| Inflammation, Depression, CTCAE | Altered Intercellular Communication | Clinical evidence increasingly suggests inflammation may be important specifically for an etiologically distinct depression subtype, characterised by resistance to antidepressant medication. | 28728805 |
| Inflammation, Depression, CTCAE, Psychological Distress | Altered Intercellular Communication | However, epidemiological investigations of the relationship of inflammation with depression and psychological distress have failed to acknowledge these developments, which may have resulted in bias or masking of associations driven by the subtype. | 28728805 |
| Inflammatory, Inflammation | Altered Intercellular Communication | An antidepressant-resistant, inflammatory depression subtype would result in stronger associations of depressive symptomatology with inflammation among antidepressant users than non-users, due to over-representation of subtype individuals among antidepressant users experiencing severe or persistent symptoms. | 28728805 |
| Inflammation, COL4A2 wt Allele | Altered Intercellular Communication | MIF in serum might be a potential biomarker for reflecting inflammation, severity and prognosis of ICH patients. | 28729134 |
| Inflammation, Adenocarcinoma of large intestine | Altered Intercellular Communication | Implications of inflammation and remodeling of the enteric glial cells in colorectal adenocarcinoma. | 28730232 |
| Chronic dacryocystitis, Inflammation | Altered Intercellular Communication | Chronic dacryocystitis (CD) is an inflammation of the lacrimal sac and nasolacrimal duct with a long-standing evolution. | 28730240 |
| Chronic lymphocytic inflammation | Altered Intercellular Communication | The sac wall revealed chronic diffusion (88.88%) or nodular lymphocytic inflammation (11.11%). | 28730240 |
| Inflammation | Altered Intercellular Communication | Applying CIS system, the majority of cases (13 patients, 72.22%) were identified with moderate chronic inflammation, only one case (5.55%) pointed out a mild degree of inflammation with a CIS<3, but four (22.22%) cases showed severe inflammatory changes with a CIS>6. | 28730240 |
| Inflammation, Asthma, Airway Obstruction | Altered Intercellular Communication | Lung sound analysis (LSA) has been reported to be useful for predicting airway obstruction and inflammation in patients with bronchial asthma. | 28731412 |
| palladium, Inflammation | Altered Intercellular Communication | Lastly, we identified increased expression of the neurodegenerative marker S100B, but not CRP, in PD and MSA patients, indicating local rather than systemic inflammation. | 28732710 |
| Inflammation, COL4A2 wt Allele, Cerebral Hemorrhage | Altered Intercellular Communication | Inflammation may determine the prognosis of intracerebral hemorrhage (ICH), which has high mortality and morbidity rates. | 28733122 |
| Bronchiectasis | Altered Intercellular Communication | Effects of an Airway Clearance Device on Inflammation, Bacteriology, and Mucus Transport in Bronchiectasis. | 28733314 |
| Inflammation, Bronchiectasis | Altered Intercellular Communication | Bronchiectasis is characterized by abnormal and permanent dilation of the bronchi, caused by the perpetuation of inflammation and impairment of mucociliary clearance. | 28733314 |
| Inflammation, Bronchiectasis, Cardiac Flutter | Altered Intercellular Communication | We evaluated the effects of the flutter valve on sputum inflammation, microbiology, and transport of respiratory secretions in patients with bronchiectasis. | 28733314 |
| Inflammation | Altered Intercellular Communication | To test two interventions to reduce interleukin (IL)-6 levels, an indicator of low-grade chronic inflammation and an independent risk factor for impaired mobility and slow walking speed in older adults. | 28734043 |
| Inflammation | Altered Intercellular Communication | The ENRGISE Pilot Study will inform a larger subsequent trial that is expected to have important clinical and public health implications for the growing population of older adults with low-grade chronic inflammation and mobility limitations. | 28734043 |
| Inflammation, Asthma | Altered Intercellular Communication | Toll-like receptor 3, an innate pattern recognition receptor, is triggered by HRV, driving inflammation that can worsen asthma. | 28734844 |
| Nonalcoholic Steatohepatitis, Inflammation, Fatty degeneration, Non-alcoholic Fatty Liver Disease, Fatty Liver Disease | Altered Intercellular Communication | NAFLD comprises the spectrum from simple steatosis (nonalcoholic fatty liver, NAFL), to steatosis with inflammation (nonalcoholic steatohepatitis, NASH). | 28735109 |
| Inflammation, Electrocardiogram: myocardial infarction (finding), Atherosclerosis | Altered Intercellular Communication | The biphasic inflammation after ST-segment elevation myocardial infarction (STEMI) plays an important role in myocardial healing and progression of systemic atherosclerosis. | 28735289 |
| Inflammation, Fever, CTCAE | Altered Intercellular Communication | Fever during the second phase but not the first phase of post-STEMI inflammation was a strong associated factor with worse long-term cardiac outcomes in patients after STEMI, suggesting the need to consider the optimal timing for anti-inflammatory strategies after STEMI. | 28735289 |
| Intraocular inflammation, Corneal Opacity | Altered Intercellular Communication | No corneal opacity or intraocular inflammation was observed after topical steroid treatment for one month. | 28736046 |
| Inflammation | Altered Intercellular Communication | u-ORM measurements might provide a novel non-invasive tool for real-time monitoring of systemic inflammation, however further investigations are required to confirm it. | 28736055 |
| Inflammation, Diabetic foot ulcer | Altered Intercellular Communication | Potential of circulatory procalcitonin as a biomarker reflecting inflammation among South Indian diabetic foot ulcers. | 28736121 |
| Weight Gain, Steatohepatitis, Inflammation | Altered Intercellular Communication | DBZ protects against HFD-induced body weight gain, insulin resistance, hepatic steatosis and inflammation in mice. | 28736228 |
| Inflammation | Altered Intercellular Communication | Cobalt-treated monocytes/macrophages effectively supported Th17 inflammation, by an IL-6-dependent but not TNF-dependent mechanism. | 28736908 |
| Pain Distress Question, Inflammation, Diabetic Ketoacidosis, Nephrolithiasis | Altered Intercellular Communication | Nephrolithiasis can increase insulin resistance due to increased pain and inflammation, so these patients should be monitored closely for recurrence of DKA. | 28737266 |
| Inflammation, Hemolysis (biological function) | Altered Intercellular Communication | BackgroundProlonged storage of transfused red blood cells (RBCs) is associated with hemolysis in healthy adults and inflammation in animal models. | 28738026 |
| Inflammation, Mental disorders, GDC Comorbidity Terminology | Altered Intercellular Communication | To the extent that many psychiatric disorders are comorbid with or causally related to stress and inflammation, decreased neurogenesis could be a partial contributor to the pathophysiology of the disorders. | 28738394 |
| Drug abuse, Inflammation, Psychiatric | Altered Intercellular Communication | Therefore, it is not clear whether changes in neurogenesis that occur alongside psychiatric illnesses are a cause or a consequence of the mediating factors such as stress, drug abuse, and inflammation, which are complexly involved in the disorders. | 28738394 |
| Inflammation, Rheumatoid Arthritis | Altered Intercellular Communication | Elevated microRNA-125b promotes inflammation in rheumatoid arthritis by activation of NF-kB pathway. | 28738524 |
| Refractory anemias, Inflammation | Altered Intercellular Communication | In conclusion, our results suggest that elevated miR-125b promotes inflammation in RA by activation of NF-kB pathway. | 28738524 |
| Inflammation, Atherosclerosis | Altered Intercellular Communication | Low-grade inflammation, represented by minor C-reactive protein (CRP) elevation, has a critical role in the early stages of atherosclerosis, and pantothenic acid (PA) may have an antioxidant effect in inflammatory process. | 28739188 |
| Inflammation, Choroidal Neovascularization | Altered Intercellular Communication | Inflammation has been strongly implicated in the pathogenesis of choroidal neovascularization. | 28739342 |
| Inflammation, Choroidal Neovascularization | Altered Intercellular Communication | Our data illustrate a functional role for TLR2 in the pathogenesis of choroidal neovascularization, likely by promoting inflammation of the retinal pigment epithelium, and validate TLR2 as a novel therapeutic target for reducing choroidal neovascularization. | 28739342 |
| Autoimmune Diseases, Inflammation, polychondritis | Altered Intercellular Communication | Relapsing polychondritis is a very rare autoimmune disease characterised by a relapsing inflammation of hyaline, elastic and fibrous cartilaginous tissues. | 28739564 |
| Inflammation, polychondritis, Polyarthritis | Altered Intercellular Communication | We report an elderly man who presented with recurrent bilateral ear inflammation and intermittent polyarthritis who was diagnosed with relapsing polychondritis with asymptomatic involvement of his large airways. | 28739564 |
| Pituitary Gland | Altered Intercellular Communication | Radiological evidence of pituitary inflammation was detected only in one case. | 28739711 |
| Arterial Stiffness, Inflammation | Altered Intercellular Communication | Relation between Arterial Stiffness and Markers of Inflammation and Hemostasis - Data from the Population-based Gutenberg Health Study. | 28740206 |
| Arterial Stiffness, Inflammation, Cyclophosphamide/Vincristine/Dacarbazine Regimen, Cardiovascular Diseases | Altered Intercellular Communication | The relation between inflammation, hemostasis and arterial stiffness is of pathophysiological relevance for the development of cardiovascular disease (CVD). | 28740206 |
| Arterial Stiffness, Inflammation | Altered Intercellular Communication | The results support the relation between inflammation, hemostasis and arterial stiffness measured by digital photoplethysmography. | 28740206 |
| Inflammation | Altered Intercellular Communication | Markers of inflammation and hemostasis modulate the ability of SI to identify subjects at risk for future CVD or higher mortality. | 28740206 |
| Inflammatory Bowel Diseases, Colitis | Altered Intercellular Communication | Decrease in genus Phascolarctobacterium was linked to presence of colonic inflammation regardless of IBD phenotype. | 28740343 |
| Pain Distress Question, Inflammation | Altered Intercellular Communication | Each participant was genotyped for 4392 single nucleotide polymorphisms in genes implicated in pain perception, inflammation and mood and tested for association with pain sensitivity. | 28741447 |
| Inflammation, Neoplasms | Altered Intercellular Communication | Lipids are known to influence tumour growth, inflammation and chemoresistance. | 28741687 |
| Inflammation, Arteriosclerosis, Sarcopenia | Altered Intercellular Communication | Sarcopenia and physical function are associated with inflammation and arteriosclerosis in community-dwelling people: The Yakumo study. | 28741974 |
| Inflammation, Arteriosclerosis, Skeletal muscle structure, Sarcopenia | Altered Intercellular Communication | Sarcopenia reduces physical function, while chronic inflammation causes arteriosclerosis and decreases skeletal muscle. | 28741974 |
| Inflammation, Arteriosclerosis, Sarcopenia | Altered Intercellular Communication | We conducted a cross-sectional study to elucidate the associations among sarcopenia, physical function, arteriosclerosis, and inflammation in community-dwelling people. | 28741974 |
| Inflammation, Arteriosclerosis, Sarcopenia | Altered Intercellular Communication | These findings indicate that chronic inflammation may relate arteriosclerosis and sarcopenia simultaneously. | 28741974 |
| methyldopa, Inflammation, Neurodegenerative Disorders | Altered Intercellular Communication | Increasing evidence demonstrates that inflammation and endoplasmic reticulum (ER) stress is implicated in the development and progression of age-related macular degeneration (AMD), a multifactorial neurodegenerative disease. | 28742151 |
| methyldopa, Inflammation | Altered Intercellular Communication | The present study investigates a possible intersection between ER stress and inflammation in AMD. | 28742151 |
| Amyotrophic Lateral Sclerosis, Inflammation | Altered Intercellular Communication | We identified 32 leukocyte phenotypes that were altered in ALS patients compared to age and gender matched healthy volunteers (HV) that included phenotypes of both inflammation and immune suppression. | 28742871 |
| Inflammation, Atherosclerosis | Altered Intercellular Communication | Peripheral leucocytes and tissue gene expression of granzyme B/perforin system and serpinB9: Impact on inflammation and insulin resistance in coronary atherosclerosis. | 28743062 |
| Inflammation, Atherosclerosis | Altered Intercellular Communication | GZB and PI-9 could be effective modulators for inflammation and insulin resistance in atherosclerosis. | 28743062 |
| Inflammation | Altered Intercellular Communication | As the disease progresses, the active inflammation of large vessels leads to dilation, narrowing and occlusion of the arteries. | 28743241 |
| Inflammation, Colorectal Carcinoma | Altered Intercellular Communication | A novel systematic inflammation related index is prognostic in curatively resected non-metastatic colorectal cancer. | 28743381 |
| Inflammation, Primary malignant neoplasm | Altered Intercellular Communication | IPI is readily available, independently prognostic and may reflect the host inflammation, immune and nutritional status that could have impact on cancer progression. | 28743381 |
| ARCN1 gene, Inflammation | Altered Intercellular Communication | Oxidative stress and systemic inflammation are higher in smokers and patients with COPD; however, markers that may help differentiate between smokers and patients with COPD have not yet been identified. | 28744116 |
| ARCN1 gene, Inflammation | Altered Intercellular Communication | Although smokers and patients with early COPD presented other increased systemic inflammation markers (eg, CRP) and oxidative stress (measured by AGEs), they did not differentiate smokers from COPD. | 28744116 |
| Muscle damage, Inflammation, Muscle Fatigue | Altered Intercellular Communication | The practice of prolonged exercise with high intensity, as seen in triathlon training, can cause physiological imbalances that might result in muscle fatigue, muscle damage and changes in systemic inflammatory response, thus reduce the athletes' physical performance, therefore, both adequate total caloric and macronutrient intake also the use of a specific ergogenic aid, as taurine supplementation would be an alternative to prevent inflammation and muscle damage. | 28745470 |
| Cessation of life, Inflammation, Amyloidosis, Kidney Failure | Altered Intercellular Communication | AA amyloidosis is a serious complication of persistent inflammation, which, untreated will progress to renal failure and death. | 28745926 |
| Inflammation | Altered Intercellular Communication | A heparin-surface-modified IOL may reduce the incidence of recurrent inflammation. | 28746181 |
| Autoimmune Diseases, Inflammation, AAVS1 gene, Vasculitis, CTCAE | Altered Intercellular Communication | Anti-neutrophil cytoplasmic antibody (ANCA)-associated vasculitis (AAV) is a group of autoimmune diseases characterized by systemic inflammation in small- to medium-sized blood vessels. | 28746217 |
| Schistosomiasis, Anemia, Congenital Abnormality | Altered Intercellular Communication | Schistosomiasis is a parasite-related chronic inflammatory condition that can cause anemia, decreased growth, liver abnormalities, and deficits in cognitive functioning among children. | 28746403 |
| Inflammation, Malignant Neoplasms | Altered Intercellular Communication | Leucine-rich a2-glycoprotein-1 (LRG1) is overexpressed during inflammation and is associated with various malignancies. | 28746773 |
| Inflammation, Anemia | Altered Intercellular Communication | Identically, in the subgroup of 76 patients with no inflammation (CRP <5 mg/L) and no iron deficiency (TSAT >20%) linear regression between IAA, IS or PCS and any anemia parameter did not reach significance. | 28747155 |
| Acute Kidney Injury, CTCAE, Acute Coronary Syndrome, Inflammation | Altered Intercellular Communication | Acute coronary syndrome and acute kidney injury: role of inflammation in worsening renal function. | 28747177 |
| Inflammation, GDC AJCC Clinical Stage Terminology | Altered Intercellular Communication | Inflammation and its components play an important role in the worsening of renal function in ACS. | 28747177 |
| Pain Distress Question, Inflammation | Altered Intercellular Communication | Associations were maintained in fully adjusted models of intrusive body pain and difficulty climbing stairs, but for chair rise speed they were fully accounted for by inflammation, body-size and lifestyle. | 28747665 |
| Giant Cell Arteritis, Inflammation, GCA gene, Musculoskeletal Pain | Altered Intercellular Communication | Monocytes/macrophages are critical in systemic and local inflammation in giant cell arteritis (GCA) and possibly in clinically overlapping polymyalgia rheumatica (PMR). | 28747747 |
| Inflammation, Metabolic Syndrome X | Altered Intercellular Communication | Involvement of the leptin-adiponectin axis in inflammation and oxidative stress in the metabolic syndrome. | 28747790 |
| Inflammation, Metabolic Syndrome X, MS gene | Altered Intercellular Communication | The aim of the present work was to study whether the leptin-adiponectin axis may have a pathophysiological role in the increased systemic inflammation and oxidative stress observed in patients with the metabolic syndrome (MS). | 28747790 |
| Inflammation | Altered Intercellular Communication | We concluded that a dysfunctional adipose tissue as suggested by a low adiponectin/leptin ratio may contribute to the increased oxidative stress and inflammation, hallmarks of the MS. | 28747790 |
| Granulomatosis, Orofacial, Inflammation | Altered Intercellular Communication | Orofacial granulomatosis (OFG) is the term given to a group of diseases characterized by the presence of non-necrotizing granulomatous inflammation affecting the soft tissues of the orofacial region. | 28748609 |
| Inflammation, Obesity | Altered Intercellular Communication | suPAR may be a good novel biomarker for systemic subclinical inflammation and immune activation linked to adolescent obesity. | 28749394 |
| Airway structure, Signs and Symptoms, Respiratory | Altered Intercellular Communication | The study provides evidence that airway inflammation and the frequency of respiratory symptoms increase, whereas lung function decreases with increased ozone exposure in schoolchildren. | 28749779 |
| Inflammation, Fibrosis Assessment | Altered Intercellular Communication | Signal intensity on T2WI images was used to distinguish between inflammation and fibrosis. | 28750685 |
| Inflammation, Fibrosis Assessment | Altered Intercellular Communication | ORN of the hyoid bone were detected in 30% of patients after treatment, with 23% of them showing inflammation and 7.7% fibrosis. | 28750685 |
| Stable chronic Graft vs Host Disease, Inflammation | Altered Intercellular Communication | These results identify dual TCR cells as specific mediators of pathogenic inflammation underlying cGVHD and highlight Tbet-driven T cell function as a potential pathway for potential therapeutic targeting. | 28750779 |
| Inflammation, Lupus Nephritis, Vasculitis, CTCAE, Necrosis | Altered Intercellular Communication | Class IV-S lupus nephritis is often associated with more necrosis and fewer subendothelial immune deposits compared to class IV-G lupus nephritis, suggestive of necrotising glomerular inflammation found in antineutrophil cytoplasmic antibody (ANCA)-associated vasculitis. | 28750930 |
| Inflammation, Dentigerous Cyst | Altered Intercellular Communication | Significant association of high-grade inflammation and thick lining epithelium with the increased number of Langerhans cells in dentigerous cysts. | 28751089 |
| Inflammation | Altered Intercellular Communication | A significant association of high-grade inflammation and thick lining epithelium with the increased LC number in DCs is found. | 28751089 |
| Pancreatitis, Epigastric pain | Altered Intercellular Communication | BACKGROUND Acute pancreatitis is an inflammatory condition of the pancreas characterized clinically by epigastric abdominal pain and elevated levels of pancreatic enzymes in the blood. | 28751631 |
| Calcinosis | Altered Intercellular Communication | Vitamin D seems an intriguing molecule to explore in the field of AAD since it improves endothelial function and protects smooth muscle cells from inflammation-induced remodeling, calcification, and loss of function, all events which are strongly related to the aging process. | 28751822 |
| Dyspnea, Wheezing | Altered Intercellular Communication | The patient presented with stubborn dyspnea and wheezing although received integrated treatment, including anti-infection, anti-inflammation, and intravenous immunoglobulin. | 28752681 |
| Inflammation, Acantholysis | Altered Intercellular Communication | PD-1 inhibitor-associated lichenoid inflammation with incidental suprabasilar acantholysis or vesiculation-Report of 4 cases. | 28753231 |
| Inflammation, Spongiosis | Altered Intercellular Communication | In 2 patients, the clefts were well developed and had some acantholytic cells while the other 2 appeared to be spongiosis or inflammation related. | 28753231 |
| Inflammation, Hypothyroidism, Hashimoto Disease, Autoimmune Thyroid Disease Pathway, Haiti, Vitamin D measurement | Altered Intercellular Communication | Hashimoto's thyroiditis (HT), the most frequent autoimmune thyroid disease (AITD), is characterized by chronic inflammation of the thyroid gland that usually results in hypothyroidism. | 28753406 |
| Inflammation, Diabetes Mellitus | Altered Intercellular Communication | Associations between self-reported diabetes and 78 circulating markers of inflammation, immunity, and metabolism among adults in the United States. | 28753646 |
| Inflammation, Diabetes Mellitus | Altered Intercellular Communication | Inflammation is increasingly thought to be associated with diabetes; however, only a few inflammation markers have been assessed concurrently in relation to history of diabetes. | 28753646 |
| Inflammation, Diabetes Mellitus | Altered Intercellular Communication | These results highlight the need to explore in future prospective studies the role of inflammation markers in diabetes. | 28753646 |
| Inflammation | Altered Intercellular Communication | Nonsteroidal anti-inflammatory drugs (NSAIDs) reduce inflammation and also PSA elevations due to intraprostatic inflammation. | 28753870 |
| Inflammation, Malignant Neoplasms, Dysbiosis | Altered Intercellular Communication | The pathogenesis of gut inflammation, bacterial dysbiosis and increased rates of malignancy in CF is unclear. | 28754328 |
| Inflammation, Malignant Neoplasms | Altered Intercellular Communication | Fecal M2-pyruvate kinase (M2-PK) is a biomarker indicative of cellular proliferation that may be raised in intestinal malignancy and inflammation. | 28754328 |
| Inflammation, Coronary Artery Disease | Altered Intercellular Communication | We also determined whether this relationship was independent of coronary artery disease (CAD) and hs-CRP, a marker of systemic inflammation. | 28754439 |
| Inflammation, Coronary Artery Disease | Altered Intercellular Communication | This effect is independent of the presence of coronary artery disease and also systemic inflammation. | 28754439 |
| Inflammation, Prostate carcinoma | Altered Intercellular Communication | A Prospective Study of Chronic Inflammation in Benign Prostate Tissue and Risk of Prostate Cancer: Linked PCPT and SELECT Cohorts. | 28754796 |
| Diabetic Retinopathy, Inflammation | Altered Intercellular Communication | Diabetic retinal maculopathy is associated with acute and chronic local inflammation. | 28755024 |
| Inflammation | Altered Intercellular Communication | Acute phase factors may contribute to local inflammation in DME and may therefore influence disease progression. | 28755024 |
| Inflammation, Fibrosis Assessment, Secondary malignant neoplasm of liver, Colorectal Carcinoma | Altered Intercellular Communication | The hepatic microenvironment, which may include chronic inflammation and fibrosis, is considered to contribute to the pathogenesis of liver metastases of colorectal cancer. | 28755421 |
| Inflammation, Jaw Keratocyst | Altered Intercellular Communication | Significant association of inflammation grade with the number of Langerhans cells in odontogenic keratocysts. | 28755796 |
| Inflammation | Altered Intercellular Communication | The mean LC counts in the lining epithelia and subepithelial connective tissues increased significantly from no inflammation (0.5 +- 0.4 and 0.7 +- 0.6 cell/high-power field or HPF, respectively) through mild/moderate inflammation (5.9 +- 2.7 and 5.0 +- 3.5 cells/HPF, respectively) to severe inflammation OKC sites (14.7 +- 5.3 and 13.3 +- 6.8 cells/HPF, respectively; all P-values < 0.001). | 28755796 |
| Inflammation | Altered Intercellular Communication | OKC sites with inflammation had thicker lining epithelia than those without inflammation. | 28755796 |
| Inflammation | Altered Intercellular Communication | A significant association of inflammation grade with the number of LCs in OKCs is found. | 28755796 |
| Inflammation, Aggressive behavior | Altered Intercellular Communication | The paucity of finding LCs in the lining epithelia of OKCs without inflammation indicates the loss of immunosurveillance ability against the OKC lining epithelial cells; this can explain why OKCs have aggressive clinical behavior, a great growth potential, and a high recurrence rate. | 28755796 |
| Inflammation, Malnutrition, Myocardial | Altered Intercellular Communication | Low total T3 levels are common in dialysis patients and are associated with inflammation, malnutrition and myocardial damage. | 28755902 |
| Primary sclerosing cholangitis, Inflammation, Ulcerative Colitis | Altered Intercellular Communication | Patients With Ulcerative Colitis and Primary Sclerosing Cholangitis Frequently Have Subclinical Inflammation in the Proximal Colon. | 28756053 |
| Inflammation, Neoplasms, Ulcerative Colitis | Altered Intercellular Communication | Histologic inflammation is an independent risk factor for the development of neoplasia; we investigated whether patients with UC and PSC have more subclinical disease activity than patients with UC alone. | 28756053 |
| Discordance, Inflammation, Ulcerative Colitis | Altered Intercellular Communication | In each colonic segment, differences in disease activity and the degree of discordance between endoscopic and histologic inflammation among UC patients with and without PSC were compared. | 28756053 |
| Inflammation, Ulcerative Colitis | Altered Intercellular Communication | Patients with UC and PSC who are in clinical remission are significantly more likely to have endoscopic and histologic inflammation in the right colon than patients with UC without PSC. | 28756053 |
| Inflammation, Peri-Implantitis | Altered Intercellular Communication | These results suggested that probiotics prevent inflammation by affecting host responses rather than improving microbial flora in peri-implant sulci in peri-implantitis patients. | 28756115 |
| Inflammation, Arthritis, Weight decreased, Osteoarthritis, Knee | Altered Intercellular Communication | Effects of dietary weight loss with and without exercise on interstitial matrix turnover and tissue inflammation biomarkers in adults with knee osteoarthritis: the Intensive Diet and Exercise for Arthritis trial (IDEA). | 28756278 |
| Degenerative polyarthritis, Inflammation, Overweight | Altered Intercellular Communication | Overweight and obese adults with knee OA who lost weight from diet and diet plus exercise reduced serum markers of interstitial matrix turnover and inflammation but not type II collagen degradation. | 28756278 |
| Autoimmune Diseases, Inflammation | Altered Intercellular Communication | Activated macrophages exhibiting diverse phenotypes and various functions contribute to the pathogenesis or amelioration of different diseases like cancer, inflammation, and infectious and autoimmune diseases. | 28756520 |
| Inflammation, ASF1A gene, Cartilage damage, Erosion of bone | Altered Intercellular Communication | We found that CypA aggravated the severity of CIA in mice, as assessed by the increase of clinical score of inflammation, cartilage damage, and bone erosion. | 28756520 |
| Gastrointestinal inflammation, Allergy - Charge Type Reason | Altered Intercellular Communication | Low vitamin D status is linked to increased incidence of food allergy and intestinal inflammation. | 28757197 |
| Hyperglycemia, Inflammation, Diabetes Mellitus, Non-Insulin-Dependent | Altered Intercellular Communication | Chronic hyperglycaemia in type 2 diabetes (T2D) is associated with increased oxidative stress and inflammation. | 28757426 |
| Inflammation, Gastrointestinal mucositis, Peri-Implantitis | Altered Intercellular Communication | Some data imply that Metalloproteinase-8 (MMP-8) level examination in peri-implant sulcular fluid (PISF) might be useful for evaluating the condition of peri-implant tissues and monitoring a development of peri-implant inflammation, including both mucositis and peri-implantitis. | 28757684 |
| Inflammation, Varicose Ulcer | Altered Intercellular Communication | Sustained high levels of activated polymorphonuclear leukocytes (PMNs) and PMN-derived proteases in the microenvironment of chronic venous leg ulcers (CVLUs) are linked to chronic inflammation and delayed healing. | 28758717 |
| Inflammation, Diabetes Mellitus | Altered Intercellular Communication | Diabetes at follow-up was also associated with high c-f PWV, however, this relationship was independent of low grade inflammation. | 28759613 |
| Arterial Stiffness, Inflammation | Altered Intercellular Communication | The results indicate that low grade inflammation is associated with arterial stiffness in addition to established cardiovascular risk factors. | 28759613 |
| Inflammation, Ulcerative Colitis | Altered Intercellular Communication | Reliability of EUS indices to detect inflammation in ulcerative colitis. | 28760533 |
| Inflammation, Ulcerative Colitis | Altered Intercellular Communication | EUS is a potentially useful modality to assess severity of inflammation in ulcerative colitis (UC). | 28760533 |
| Inflammation, cell wall thickening, Hyperemia | Altered Intercellular Communication | The revised EUS-UC score included bowel wall thickening, depth of inflammation, and hyperemia. | 28760533 |
| Anemia, Sickle Cell, Inflammation, SLC22A5 gene | Altered Intercellular Communication | Sickle cell disease (SCD) is a genetic disease caused by mutations in the beta globin gene, and inflammation plays a key role in driving many aspects of disease pathology. | 28760671 |
| Inflammation, Chronic Fatigue Syndrome | Altered Intercellular Communication | Although some signs of inflammation have been reported previously in patients with myalgic encephalomyelitis or chronic fatigue syndrome (ME/CFS), the data are limited and contradictory. | 28760971 |
| Inflammation | Altered Intercellular Communication | High-throughput methods now allow us to interrogate the human immune system for multiple markers of inflammation at a scale that was not previously possible. | 28760971 |
| vascular inflammations | Altered Intercellular Communication | Smoking cessation reduces the lectin-like low-density lipoprotein receptor index, an independent cardiovascular risk marker of vascular inflammation. | 28761986 |
| Inflammation, atherosclerotic | Altered Intercellular Communication | Vessel wall inflammation promotes the destabilization of atherosclerotic plaques. | 28761986 |
| Inflammation, Dyslipidemias | Altered Intercellular Communication | The LOX index is closely associated with smoking heaviness as well as dyslipidemia and an inflammation marker. | 28761986 |
| Inflammation, Atherosclerosis | Altered Intercellular Communication | Moderate alcohol consumption is causally related to lower risk of atherosclerosis through changes in lipid profiles and inflammation. | 28762059 |
| Inflammation, Cardiovascular Diseases | Altered Intercellular Communication | Background The Proximity Extension Assay proteomics chip provides a large-scale analysis of 92 biomarkers linked to cardiovascular disease or inflammation. | 28762762 |
| Communicable Diseases, Inflammation, Periodontal Diseases, Osteopenia | Altered Intercellular Communication | Chronic periodontal disease is an infectious disease consisting of prolonged inflammation of the supporting tooth tissue and resulting in bone loss. | 28764802 |
| Inflammation, Neoplasms | Altered Intercellular Communication | Inflammation plays an important role in tumor development and response to therapy. | 28764811 |
| Inflammation, Erythema, Swelling | Altered Intercellular Communication | Clinical examination revealed no signs of swelling, redness, or inflammation in the gingival or surrounding soft tissue. | 28764980 |
| hydrocortisone, Inflammation, Data types - Address | Altered Intercellular Communication | Compared to IL1b-induced inflammation, HC have increased CD14 levels after vitamin D treatment (p<0.001), whereas the IL1b-induced CD14 expression of AD patients' monocytes did not change after vitamin D treatment (p=0.8). | 28765037 |
| Inflammation, Data types - Address | Altered Intercellular Communication | AD patients carrying HLA high-risk haplotypes showed an increased CCL-2 expression after IL1b-induced inflammation compared to intermediate-risk HLA carriers (p=0.05). | 28765037 |
| Inflammation, Organ Dysfunction Scores | Altered Intercellular Communication | However, these patients now survive to enter state of chronic critical illness (CCI), persistent low-grade organ dysfunction and poor long-term outcomes driven by the persistent inflammation, immunosuppression and catabolism syndrome (PICS). | 28765125 |
| Spondylitis | Altered Intercellular Communication | A chronic inflammatory condition manifesting in young adulthood, ankylosing spondylitis (AS) affects both physical and emotional quality of life (QOL). | 28765244 |
| Inflammation, Muscle (organ) | Altered Intercellular Communication | The pathophysiology is multifactorial, with loss of muscle satellite cells, changes in hormonal systems, chronic inflammation, oxidative stress and anabolic resistance to protein utilisation all implicated. | 28765418 |
| Inflammation, Muscle (organ) | Altered Intercellular Communication | The pathophysiology is multifactorial, with loss of muscle satellite cells, changes in hormonal systems, chronic inflammation, oxidative stress and anabolic resistance to protein utilisation all implicated. | 28765418 |
| Inflammatory disease of mucous membrane, Gastritis, Atrophic | Altered Intercellular Communication | Anti-CagA-IgG seropositivity was strongly associated with atrophic gastritis, increased mucosal inflammation according to the Sydney score, IL-8 and cagA mRNA expression. | 28765692 |
| Inflammation | Altered Intercellular Communication | The core peri-implant microbiome harbours taxa from genera often associated with periodontal inflammation. | 28766745 |
| Inflammation, hyperthermia treatment, Hyperemia | Altered Intercellular Communication | The signs of inflammation such as hyperemia and hyperthermia might suggest the possible participation of inflammatory mediators. | 28766916 |
| IgG4-Related Sclerosing Disease | Altered Intercellular Communication | IgG4-related disease is an immune-mediated fibro-inflammatory condition that affects multiple organ systems. | 28768224 |
| Sepsis, Communicable Diseases, Inflammation, Endotoxemia | Altered Intercellular Communication | The pattern of change in the postoperative period of intestinal permeability, systemic endotoxemia and elastase concentration is significantly higher in patients in whom sepsis develops, while the concentration of IL-1b, IL-6, and CRP does not permit to distinguish infection from inflammation. | 28768258 |
| Inflammation, Carcinoma, Transitional Cell, Neoplasms, Necrosis | Altered Intercellular Communication | Tumour front inflammation and necrosis are independent prognostic predictors in high-grade urothelial carcinoma of the bladder. | 28768702 |
| Inflammation, Malignant Neoplasms, Necrosis | Altered Intercellular Communication | Inflammation and necrosis have been associated with prognosis in multiple epithelial malignancies. | 28768702 |
| Inflammation, Carcinoma, Neoplasms, Necrosis | Altered Intercellular Communication | The relationship of inflammation and necrosis with stage, nodal status, carcinoma in situ, tumour size, margin status and vascular space invasion and the impact on relapse-free and disease-specific survival were calculated using appropriate statistical tests. | 28768702 |
| Inflammation, Necrosis | Altered Intercellular Communication | On multivariate analysis, invasive front inflammation (p=0.003) and necrosis (p=0.000) were independent predictors of relapse-free survival. | 28768702 |
| Inflammation, Necrosis | Altered Intercellular Communication | Both invasive front inflammation (p=0.009) and necrosis (p=0.002) again were independent predictors of disease-specific survival. | 28768702 |
| Inflammation, Carcinoma | Altered Intercellular Communication | For pathological features, low invasive front inflammation was associated with lymphovascular space invasion (p=0.008), a positive soft tissue margin (p=0.028) and carcinoma in situ (p=0.042). | 28768702 |
| Inflammation, Carcinoma, Transitional Cell, Necrosis | Altered Intercellular Communication | Necrosis and invasive front inflammation are additional histological variables with independent prognostic relevance in high-grade urothelial carcinoma of the bladder. | 28768702 |
| Inflammation, Plaque, Atherosclerotic | Altered Intercellular Communication | Our data could indicate that LOY affects secondary outcome via other mechanisms than inflammation in the atherosclerotic plaque. | 28768751 |
| Inflammation, Malaria | Altered Intercellular Communication | We measured biomarkers of nutritional and inflammation status and malaria. | 28768839 |
| deficiency aspects, Hematoma, Subdural, Chronic | Altered Intercellular Communication | However, the relationship between milder head trauma-such as chronic subdural hematoma - and the occurrence of hormonal deficiency is uncertain. | 28768968 |
| Inflammation | Altered Intercellular Communication | The pathophysiology is poorly understood, but it has been suggested that inflammation and oxidative stress may play a role. | 28769556 |
| Inflammation, Primary malignant neoplasm, Hemorrhage, Fibrosis Assessment, Edema | Altered Intercellular Communication | 41 patients (66.1%) were pathologically diagnosed with cancer, 10 were diagnosed with inflammation, 7 with fibrosis, and 4 with edema, hemorrhage and other lesions. | 28770963 |
| Inflammation, Hypertension, CTCAE, Chronic Kidney Diseases | Altered Intercellular Communication | A hypothesized mechanism linking hypertension and progressive chronic kidney disease (CKD) is the innate immune response and inflammation. | 28771472 |
| Adult Glioblastoma, Glioblastoma Multiforme Pathway | Altered Intercellular Communication | The perivascular niche is critical for intercellular communication between resident cell types in glioblastoma (GBM), and it plays a vital role in maintaining the glioma stem cell (GSC) microenvironment. | 28771552 |
| Sepsis, Inflammation, Septic Shock | Altered Intercellular Communication | In addition, 20 patients with post-surgical inflammation, 20 patients with sepsis or septic shock were included and TNFa was determined following ex vivo stimulation of whole blood with 500 pg/mL LPS. | 28771573 |
| Airway structure, Asthma, Occupational | Altered Intercellular Communication | Assessment of eosinophilic airway inflammation as a contribution to the diagnosis of occupational asthma. | 28771844 |
| Inflammation | Altered Intercellular Communication | Subjects with abnormal T-axis showed higher levels of subclinical inflammation, hs-troponin I and hs-NT-proBNP (p < 0.001 for all). | 28772106 |
| Primary malignant neoplasm | Altered Intercellular Communication | Nivolumab Enhances the Inflammation of the Irradiation Field in Advanced Non-Small Cell Lung Cancer. | 28774862 |
| Inflammation, Depression, CTCAE, Diabetic Angiopathies | Altered Intercellular Communication | Elevated innate inflammation may be common to both depression and macrovascular diabetes complications, but these findings require replication. | 28776084 |
| Intraocular inflammation, Ocular syphilis, Uveitis | Altered Intercellular Communication | PurposeTo present the patient profiles, clinical presentations and visual outcomes in those diagnosed with ocular syphilis, attending a subspecialist uveitis service in northern England over a 15-year period.Patients and methodsRetrospective observational case series of patients presenting between January 2002 and December 2016.ResultsA total of 50 eyes of 34 patients had intraocular inflammation due to syphilis. | 28776596 |
| Inflammation, Hemorrhage, Peri-Implantitis, Suppuration, Communicable Diseases, Osteopenia | Altered Intercellular Communication | Peri-implantitis is an infectious disease characterized by inflammation of the tissues surrounding the implant, bleeding on probing with or without suppuration, and bone loss. | 28778496 |
| Inflammation | Altered Intercellular Communication | This situation could be related to chronic inflammation and HDL metabolism. | 28778575 |
| Inflammation, Cardiovascular Diseases | Altered Intercellular Communication | Increased inflammation and impaired endothelial function may be pathways by which chronic PTSD increases cardiovascular disease risk. | 28778657 |
| Inflammation | Altered Intercellular Communication | Systemic inflammation and immune response are the major factors influencing the outcome and quality of patient with AECOPD. | 28779230 |
| Inflammation, Orbital lymphoma | Altered Intercellular Communication | Diffusivity of intraorbital lymphoma vs. inflammation: comparison of single shot turbo spin echo and multishot echo planar imaging techniques. | 28779398 |
| Inflammation, Lymphoma | Altered Intercellular Communication | Twenty-nine patients with pathologically confirmed lymphomas and 39 patients with inflammation were imaged with a 3.0-T system. | 28779398 |
| Inflammation, Lymphoma | Altered Intercellular Communication | The ADCs derived from the TSE DWI of the lymphomas (0.68 +- 0.14 x 10-3 mm2/s) were significantly lower than those of the inflammation cases (1.04 +- 0.39 x 10-3 mm2/s; p < 0.001). | 28779398 |
| Inflammation, Lymphoma | Altered Intercellular Communication | The ADCs derived from MSh DWI could not be used to separate the lymphomas from the inflammation (1.16 +- 0.43 x 10-3 mm2/s vs. 1.36 +- 0.48 x 10-3 mm2/s; p = 0.06). | 28779398 |
| Inflammation, Lymphoma | Altered Intercellular Communication | Conventional sequences also could not separate the lymphomas from the inflammation (p > 0.05). | 28779398 |
| Inflammation, Orbital lymphoma | Altered Intercellular Communication | The ADCs derived from TSE DWI might help to differentiate orbital lymphomas from inflammation. | 28779398 |
| Inflammation, Lymphoma | Altered Intercellular Communication | * ADC of lymphoma was significantly lower than that of inflammation. | 28779398 |
| Pneumonia, Meningitis, Airway structure, Sepsis, Bronchitis, Respiratory Tract Infections | Altered Intercellular Communication | The samples were collected from children aged 0-14 years with conditions such as respiratory tract infections (upper airway inflammation, bronchitis, and pneumonia), meningitis, and sepsis. | 28779495 |
| Inflammation, Malnutrition, Obesity | Altered Intercellular Communication | Obesity and malnutrition similarly alter the renin-angiotensin system and inflammation in mice and human adipose. | 28779634 |
| Inflammation, Metabolic Diseases | Altered Intercellular Communication | A similar profile was observed in the adipose tissue of obese and malnourished humans, supporting the critical role of inflammation and RAS as mediators of metabolic disorders. | 28779634 |
| Inflammation, Coronary Artery Disease, Heart failure | Altered Intercellular Communication | Inflammation is a shared mechanism in coronary artery disease (CAD) and subsequent heart failure (HF), and circulating monocyte and lymphocyte counts predict CAD severity and outcomes. | 28779870 |
| Communicable Diseases, Malnutrition, Diarrhea, Inflammation | Altered Intercellular Communication | The impact of enteroaggregative E. coli (EAEC) infection on childhood malnutrition and inflammation has been suggested, regardless of diarrhea. | 28780245 |
| Hereditary Autoinflammatory Diseases, Inflammation, Fever, CTCAE, Brucellosis, Familial Mediterranean Fever | Altered Intercellular Communication | Familial Mediterranean fever (FMF) is a genetic autoinflammatory disease characterized by recurrent fever with serosal inflammation. | 28781304 |
| Inflammation, Necrosis | Altered Intercellular Communication | In her first liver biopsy, necrosis and inflammation was limited to the centrilobular area, while the second biopsy showed different findings. | 28781316 |
| Arthritis | Altered Intercellular Communication | Down-regulation of miR-10a-5p in synoviocytes contributes to TBX5-controlled joint inflammation. | 28782180 |
| Refractory anemias, Inflammation, Arthritis | Altered Intercellular Communication | We conclude that miR-10a-5p in a relation with TBX5 regulates joint inflammation in arthritis, which would serve as a diagnostic and therapeutic target for RA treatment. | 28782180 |
| Muscle Weakness, Inflammation, Edema, Disease remission | Altered Intercellular Communication | Inflammation and focal or generalized muscle edema were present on US in the remaining five patients with muscular weakness suggesting active disease. | 28782262 |
| Inflammation, Cystic artery pseudoaneurysm, Traumatic injury, Cholecystitis | Altered Intercellular Communication | Cystic artery pseudoaneurysm is a rare entity most closely associated with trauma to the biliary vasculature (usually iatrogenic) or inflammation from adjacent cholecystitis. | 28782418 |
| Inflammation, Benign prostatic hypertrophy | Altered Intercellular Communication | Yongdamsagan-tang, a traditional herbal formula, inhibits cell growth through the suppression of proliferation and inflammation in benign prostatic hyperplasia epithelial-1 cells. | 28782621 |
| Inflammation, Ischemic stroke | Altered Intercellular Communication | Acute ischaemic stroke (AIS) triggers both systemic and neurovascular inflammation, influencing poststroke recovery. | 28783210 |
| Inflammation, Reperfusion Injury | Altered Intercellular Communication | In smokers with AIS, inflammation might be further upregulated, increasing ischaemia/reperfusion injury. | 28783210 |
| Airway structure, Allergic sensitization | Altered Intercellular Communication | We cross-sectionally investigated the relationships among respiratory symptoms and function, airway inflammation, allergen sensitization, and indoor allergen concentration. | 28783215 |
| Airway structure, Atopy | Altered Intercellular Communication | In atopic children, sensitizing allergens in the indoor environment may increase airway inflammation worsening pulmonary function. | 28783215 |
| Gastroesophageal reflux disease, Inflammation | Altered Intercellular Communication | The PMA gingival indexes, as a measurement for gingival inflammation, and OHI-S, as a measure for oral hygiene, in the GERD patients were significantly higher than in either of the controls (all P < 0.05). | 28784097 |
| Inflammation, Leptomeningitis | Altered Intercellular Communication | Teaching NeuroImages: Cerebral amyloid angiopathy-related inflammation presenting with isolated leptomeningitis. | 28784645 |
| Inflammation, Reperfusion Injury | Altered Intercellular Communication | Here, we investigated the role of serum iron in the sterile inflammation that follows kidney ischemia-reperfusion injury. | 28784700 |
| Inflammation, Reperfusion Injury | Altered Intercellular Communication | In mice, systemic iron overload protected against renal ischemia-reperfusion injury-associated sterile inflammation. | 28784700 |
| Inflammation, Endothelial dysfunction | Altered Intercellular Communication | Several circulating proteins involved in phosphate homeostasis, inflammation, apoptosis, extracellular matrix remodeling, angiogenesis, and endothelial dysfunction were associated with worsening kidney function. | 28784837 |
| Inflammation, Ulcerative Colitis | Altered Intercellular Communication | Short-term treatment with eicosapentaenoic acid improves inflammation and affects colonic differentiation markers and microbiota in patients with ulcerative colitis. | 28785079 |
| Inflammation | Altered Intercellular Communication | EPA-FFA improved endoscopic and histological inflammation and induced IL-10, SOCS3, HES1 and KLF4 in compliant and responder patients. | 28785079 |
| Inflammation, Ulcerative Colitis | Altered Intercellular Communication | In conclusion, EPA-FFA supplementation reduced mucosal inflammation, promoted goblet cells differentiation and modulated intestinal microbiota composition in long-standing UC patients. | 28785079 |
| Inflammation, Respiration Disorders, Thrombus, Traumatic injury, terminal cancer, Morbid obesity | Altered Intercellular Communication | Those with recurring thrombotic episodes, cardiorespiratory disease, terminal cancer, morbid obesity, penetrating trauma or significant inflammation were excluded. | 28787773 |
| Inflammation, Esophagitis | Altered Intercellular Communication | "Lichenoid esophagitis" is a descriptive term for a lichenoid pattern of inflammation in the esophagus for which a precise histologic diagnosis cannot be established. | 28789612 |
| Inflammation, Esophagitis | Altered Intercellular Communication | Lichenoid esophagitis is an appropriate diagnostic term when clinical, histologic and laboratory findings do not allow for specific categorization of lichenoid inflammation in the esophagus. | 28789612 |
| Inflammation, Carotid Stenosis, Diabetes Mellitus, Non-Insulin-Dependent | Altered Intercellular Communication | Type 2 diabetes mellitus (T2DM) is characterized by increased inflammation and an elevated risk for embolization of carotid artery stenosis (CAS). | 28789657 |
| Inflammatory Bowel Diseases, Inflammation, Adenocarcinoma of large intestine | Altered Intercellular Communication | Colonic inflammation seen in inflammatory bowel disease (IBD) predisposes to the development of colorectal adenocarcinoma. | 28790093 |
| Inflammation, Dysplasia, Necrotizing enterocolitis in fetus OR newborn | Altered Intercellular Communication | Dysplasia from chronic inflammation leading to neuroendocrine cell differentiation may be responsible for NEC development, though this finding has not been seen consistently. | 28790093 |
| Chronic disease of skin, Inflammation, Psoriasis | Altered Intercellular Communication | Psoriasis is a chronic skin disease characterized by abnormal keratinocyte proliferation and differentiation, inflammation, and angiogenesis. | 28790132 |
| Inflammation, Primary malignant neoplasm, Psoriasis, Metabolic Syndrome X, Chronic inflammatory disorder | Altered Intercellular Communication | Psoriasis is a chronic inflammatory disease that affects skin and is associated with systemic inflammation and many serious comorbidities ranging from metabolic syndrome to cancer. | 28790368 |
| Inflammation, Arthritis, Psoriatic | Altered Intercellular Communication | We found that signs of systemic inflammation were present in most of the patients, correlated with the severity of the disease, and pointed to IL-6 involvement in the pathogenesis of psoriatic arthritis. | 28790368 |
| Inflammation, Aortic Aneurysm, Thoracic | Altered Intercellular Communication | Curcumin attenuates the development of thoracic aortic aneurysm by inhibiting VEGF expression and inflammation. | 28791384 |
| Crohn Disease | Altered Intercellular Communication | Crohn's disease (CD) is an inflammatory condition of the gastrointestinal tract that can affect the musculoskeletal system. | 28791436 |
| Fibrosis, Liver, Inflammation, Liver damage | Altered Intercellular Communication | Levels of leptin and biochemical markers of liver cell damage, liver fibrosis, inflammation and oxidative stress, and hepatocyte apoptosis were significantly higher in subjects in Q 1 than in those in Q 2, Q 3, or Q 4. | 28791501 |
| Inflammation, Tumor necrosis, Neoplasms | Altered Intercellular Communication | Inflammation contributes to tumor progression and can be induced by excessive production of pro-inflammatory cytokines such as interleukin-6 (IL-6), interleukin-8 (IL-8) and tumor necrosis factor-a (TNF-a). | 28791816 |
| Inflammation, Lung Diseases, Obstructive | Altered Intercellular Communication | These results suggest that the most important marker of inflammation in mild-to-moderate obstructive lung disease is not microbiology-dependent. | 28791839 |
| Inflammation, Joints | Altered Intercellular Communication | This may lead to increased macrophage and osteoclast activation, resulting in the increased local inflammation and bone resorption present in RA joints. | 28792533 |
| Inflammation, Interstitial Fibrosis Assessment, Kidney damage | Altered Intercellular Communication | In human HN, inflammation involving complement C3 activation and macrophage infiltration as well as interactions between them, may play important roles in the pathogenesis and progression of interstitial fibrosis and kidney damage. | 28793954 |
| Inflammation, "Alzheimers Disease", Data types - Address | Altered Intercellular Communication | Increasing evidence suggests that inflammation is involved in Alzheimer's disease (AD) pathology. | 28794151 |
| Inflammation, Pulmonary Hypertension | Altered Intercellular Communication | Association of Pulmonary Hypertension With Inflammation and Fluid Overload in Hemodialysis Patients. | 28794293 |
| Hypernatremia, Cardiac Hypertrophy, Inflammation, Pulmonary Hypertension | Altered Intercellular Communication | Pulmonary hypertension, cardiac hypertrophy, fluid overload, and inflammation were associated to each other in hemodialysis patients, providing insight into its pathogenesis. | 28794293 |
| Lymphoma of kidney, Adrenal cortical hypofunction | Altered Intercellular Communication | The Clinical and Hormonal Characteristics of Primary Adrenal Lymphomas: The Necessity of Early Detection of Adrenal Insufficiency. | 28794358 |
| Inflammation, Hypoproteinemia | Altered Intercellular Communication | After 17 months of treatment, crizotinib was switched to alectinib, followed by the recovery of hypoproteinemia and systemic inflammation. | 28794366 |
| Inflammation, Renal cyst | Altered Intercellular Communication | Switching to alectinib may be beneficial in patients demonstrating crizotinib-associated complex renal cysts with systemic inflammation and exhaustion. | 28794366 |
| Vasculitis | Altered Intercellular Communication | An extended high-frequency ultrasound protocol for detection of vessel wall inflammation. | 28795494 |
| Communicable Diseases, Inflammation, Arteritis | Altered Intercellular Communication | In the groups with sonographic signs implying arteritis (n = 29), 20 patients had a clinical diagnosis of arteritis, whereas eight patients had another main diagnosis such as malignancy/other inflammatory or infectious disease complicated by inflammation of the vessel wall. | 28795494 |
| Vasculitis | Altered Intercellular Communication | In case of atypical vessel wall inflammation, other main diagnoses should be considered. | 28795494 |
| Inflammation, Colorectal Carcinoma, Malignant Neoplasms | Altered Intercellular Communication | Colorectal cancer (CRC) is one of the most common malignant tumors worldwide, which is a heterogeneous disease and main risk factors are associated with inflammation, family history, genetic mutations, epigenetics, and so on. | 28796265 |
| Inflammation, Obesity | Altered Intercellular Communication | Lean body mass and creatine kinase are associated with reduced inflammation in obesity. | 28796313 |
| Inflammation, Obesity | Altered Intercellular Communication | Obesity is associated with inflammation, but the role of lean mass and creatine kinase (CK) on the inflammatory process is less known. | 28796313 |
| Inflammation, Obesity | Altered Intercellular Communication | Hypothetically, lean mass has a favourable effect on obesity-related inflammation, and CK may play a role as an inhibitor of inflammation in obesity. | 28796313 |
| Inflammation, HIV Infections | Altered Intercellular Communication | Inflammation occurs after HIV infection and persists, despite highly active antiretroviral therapy (HAART). | 28796748 |
| Inflammation, Gastrointestinal mucositis, Malignant Head and Neck Neoplasm | Altered Intercellular Communication | Oral mucositis is inflammation of mucosa of oral cavity which is an inevitable and acute side effect in patients undergoing chemoradiotherapy for head & neck cancer. | 28797456 |
| Inflammation, Prostate carcinoma | Altered Intercellular Communication | We propose that the urinary microbiome may influence chronic inflammation observed in the prostate, leading to prostate cancer development and progression. | 28797714 |
| Primary malignant neoplasm, prostatitis | Altered Intercellular Communication | We determined the association between bacterial species and the presence or absence of cancer, cancer grade, and type and degree of prostate inflammation. | 28797714 |
| Primary malignant neoplasm, Malignant Neoplasms, prostatitis | Altered Intercellular Communication | Many species, including known uropathogens, were significantly and differentially abundant among cancer and benign samples, in low vs higher grade cancers and in relation to prostate inflammation type and degree. | 28797714 |
| Inflammation, Autoimmune Hypophysitis | Altered Intercellular Communication | Autoimmune hypophysitis is a rare disease of the pituitary, which may affect vision by inflammation and compression of the optic chiasm. | 28799078 |
| Intestinal metaplasia, Inflammation | Altered Intercellular Communication | intestinal metaplasia and degree of inflammation, were inconclusive between the two groups. | 28799264 |
| Inflammation, Cholelithiasis, Diabetes Mellitus, Non-Insulin-Dependent, Obesity | Altered Intercellular Communication | Biomarkers of insulin resistance, systemic inflammation and genetic obesity or type 2 diabetes risk alleles seem to be associated with gallstone disease. | 28799434 |
| Data types - Address | Altered Intercellular Communication | Our findings suggest that AD GRNs show significant enrichment for key signaling mechanisms involved in neurotransmission. | 28800327 |
| Cognition Disorders, Data types - Address | Altered Intercellular Communication | Among the prioritized genes, well-known AD genes were prominent in synaptic transmission, implicated in cognitive deficits. | 28800327 |
| Plaque, Atherosclerotic | Altered Intercellular Communication | Variability in quantitative analysis of atherosclerotic plaque inflammation using 18F-FDG PET/CT. | 28800625 |
| dendritic lamellar body, Pervasive Development Disorder | Altered Intercellular Communication | The postsynaptic protein, synaptopodin (SYNPO) was significantly down-regulated in both DLB and PDD subgroups, suggesting a defective synaptic transmission in the demented patients. | 28800743 |
| physiopathological | Altered Intercellular Communication | Environmental enteric dysfunction (EED) is a subacute inflammatory condition of the small intestinal mucosa with unclear aetiology that may account for more than 40% of all cases of stunting. | 28801442 |
| Liver carcinoma | Altered Intercellular Communication | An internally validated new clinical and inflammation-based prognostic score for patients with advanced hepatocellular carcinoma treated with sorafenib. | 28801777 |
| Communicable Diseases, Inflammatory disease of mucous membrane | Altered Intercellular Communication | Calprotectin and lactoferrin are released by the gastrointestinal tract in response to infection and mucosal inflammation. | 28801865 |
| Compact Disk Interactive, Gastrointestinal inflammation | Altered Intercellular Communication | Both faecal calprotectin and lactoferrin were higher in patients with CDI, especially in those with detectable toxin in faeces, suggesting a correlation between intestinal inflammation and toxins in stools. | 28801865 |
| Inflammation | Altered Intercellular Communication | Cytochrome c levels did not increase after cardiac surgery and was not associated with the degree of inflammation or clinical outcomes. | 28802789 |
| Dyspnea, Inflammation, Depression, CTCAE, Pain Distress Question | Altered Intercellular Communication | Worse QoL was associated with increased systemic inflammation (mGPS = 1 b = -0.12, P = 0.003; mGPS = 2 b = -0.09, P = 0.023), lower physical performance (b = 0.17, P < 0.001), reduced appetite (b = -0.15, P < 0.001), breathlessness (b = -0.11, P = 0.004), pain (b = -0.14, P = 0.002), and higher depression severity (b = -0.27, P < 0.001). | 28803091 |
| ACSM3 gene, Inflammation, Subarachnoid Hemorrhage | Altered Intercellular Communication | Inflammation following subarachnoid hemorrhage (SAH) involves numerous mediators with biomarker properties. | 28803177 |
| Sepsis, Communicable Diseases, Inflammation, Endotoxemia | Altered Intercellular Communication | The pattern of change of intestinal permeability, systemic endotoxemia, and elastase concentration in the postoperative period is significantly higher in patients in whom sepsis develops, while the concentration of IL-1b, IL-6 and CRP do not permit to distinguish infection from inflammation. | 28803860 |
| Inflammation, Non-alcoholic Fatty Liver Disease, Obesity | Altered Intercellular Communication | Non-alcoholic fatty liver disease (NAFLD) affects 20%-30% of adults with risk factors like obesity and insulin resistance putatively acting through chronic low-grade inflammation. | 28804947 |
| Inflammation, Periodontitis, Non-alcoholic Fatty Liver Disease | Altered Intercellular Communication | Because periodontitis elicits low-grade inflammation, we hypothesized that it could contribute to NAFLD occurrence. | 28804947 |
| Inflammation, Traumatic injury, Respiratory Distress Syndrome, Newborn | Altered Intercellular Communication | Hypoxemic Patients With Bilateral Infiltrates Treated With High-Flow Nasal Cannula Present a Similar Pattern of Biomarkers of Inflammation and Injury to Acute Respiratory Distress Syndrome Patients. | 28806218 |
| glycation, Endothelium, Inflammation, Respiratory Distress Syndrome, Newborn | Altered Intercellular Communication | We measured plasma biomarkers of lung epithelial injury (receptor for advanced glycation end products and surfactant protein D) and endothelial injury (angiopoietin-2) and inflammation (interleukin-6, interleukin-8, and interleukin-33 and soluble suppression of tumorigenicity-2) within 24 hours of acute respiratory distress syndrome onset. | 28806218 |
| Paraganglioma | Altered Intercellular Communication | Her initial FDG PET demonstrated brown adipose tissue hyperactivation, which may have been caused by the combination of hormonal changes in pregnancy and the paraganglioma. | 28806264 |
| Inflammation, Ulcerative Colitis | Altered Intercellular Communication | Although possible in ulcerative colitis (UC) patients, the chronic inflammation may increase the procedural risks and reduce the complete resection rate. | 28806821 |
| Inflammation, Necrotizing fasciitis, Necrosis | Altered Intercellular Communication | Necrotizing myositis is a rare but life-threatening soft-tissue infection characterized by rapidly spreading inflammation and subsequent necrosis of the affected tissue. | 28807000 |
| Inflammation, Fracture | Altered Intercellular Communication | Unlike in simple stress fracture, long-term antibiotic administration and drainage surgery were required to suppress the inflammation. | 28807072 |
| Inflammation, Inflammatory disorder | Altered Intercellular Communication | Systemic inflammation was primarily assessed by neutrophil-lymphocyte ratio (NLR), where a ratio >4 is prognostic across several inflammatory diseases and correlates strongly with elevated plasma levels of pro-inflammatory cytokines. | 28807718 |
| Inflammation, Abnormal sudomotor regulation | Altered Intercellular Communication | Delayed HRR, a robust measure of parasympathetic dysfunction, is independently associated with leukocyte ratios indicative of systemic inflammation. | 28807718 |
| Weakness, Myositis, CTCAE 5.0, Myositis | Altered Intercellular Communication | Myositis is characterised by muscle inflammation and weakness. | 28808260 |
| Autoimmune Diseases, Inflammation | Altered Intercellular Communication | Plasma alpha-L-fucosidase activity in chronic inflammation and autoimmune disorders in a pediatric cohort of hospitalized patients. | 28808940 |
| Autoimmune Diseases, Inflammation | Altered Intercellular Communication | The result of the present study should encourage further research on FUCA-1 as a marker of chronic inflammation and autoimmunity. | 28808940 |
| APP gene, Inflammation, Aortic Aneurysm, Abdominal, Rupture | Altered Intercellular Communication | Inflammation detected through the uptake of ultrasmall superparamagnetic particles of iron oxide (USPIO) on magnetic resonance imaging (MRI) and finite element (FE) modelling of tissue stress both hold potential in the assessment of abdominal aortic aneurysm (AAA) rupture risk. | 28808955 |
| APP gene, Inflammation | Altered Intercellular Communication | It is suggested that cellular inflammation and stress may represent different but complimentary aspects of AAA disease progression. | 28808955 |
| Inflammation, Bipolar Disorder | Altered Intercellular Communication | Repeated exposure to systemic inflammation and risk of new depressive symptoms among older adults. | 28809860 |
| Inflammation, Depression, CTCAE | Altered Intercellular Communication | Evidence on systemic inflammation as a risk factor for future depression is inconsistent, possibly due to a lack of regard for persistency of exposure. | 28809860 |
| Inflammation, Bipolar Disorder | Altered Intercellular Communication | In further analyses, 2 vs 0 occasions of inflammation were associated with increased odds of developing depressive symptoms among women (odds ratio (OR)=2.75, 95% CI=1.53, 4.95), but not among men (OR=0.70, 95% CI=0.29, 1.68); P-for-sex interaction=0.035. | 28809860 |
| Inflammation, Bipolar Disorder | Altered Intercellular Communication | In this cohort study of older adults, repeated but not transient exposure to systemic inflammation was associated with increased risk of future depressive symptoms among women; this subgroup finding requires confirmation of validity. | 28809860 |
| Inflammation, Spinal Cord Injuries | Altered Intercellular Communication | FEV1 and FVC and systemic inflammation in a spinal cord injury cohort. | 28810847 |
| Inflammation | Altered Intercellular Communication | Systemic inflammation has been associated with reduced pulmonary function in individuals with and without chronic medical conditions. | 28810847 |
| Inflammation, Spinal Cord Injuries, Stanford Cancer Institute | Altered Intercellular Communication | Individuals with chronic spinal cord injury (SCI) have clinical characteristics that promote systemic inflammation and also have reduced pulmonary function. | 28810847 |
| Inflammation, Stanford Cancer Institute | Altered Intercellular Communication | We sought to assess the associations between biomarkers of systemic inflammation with pulmonary function in a chronic SCI cohort, adjusting for other potential confounding factors. | 28810847 |
| Inflammation, Stanford Cancer Institute | Altered Intercellular Communication | This finding suggests that systemic inflammation associated with chronic SCI may contribute to reduced pulmonary function. | 28810847 |
| Inflammation, Disease | Altered Intercellular Communication | Low DHEAS/cortisol ratios are associated with more severe diseases, inflammation, and CIRCI and can serve as a prognostic marker. | 28810889 |
| Granulomatous inflammation | Altered Intercellular Communication | Biopsy of the foot revealed granulomatous inflammation with predominantly lymphoplasmacytic infiltrate and multinucleated giant cells. | 28810997 |
| glycation, Inflammation, Diabetes Mellitus, Non-Insulin-Dependent, Obesity | Altered Intercellular Communication | The soluble receptor for advanced glycation end products (sRAGE) may be protective against inflammation associated with obesity and type 2 diabetes (T2DM). | 28811295 |
| Inflammation, Family history | Altered Intercellular Communication | In conclusion, circulating miR-200c is up-regulated in FH, probably due to oxidative stress and inflammation and via a miR-33a/b-ZEB1-dependent mechanism. | 28811385 |
| Inflammation, Cyclophosphamide/Vincristine/Dacarbazine Regimen, Cardiovascular Diseases | Altered Intercellular Communication | Systemic inflammation, measured by C-reactive protein (CRP), is an important risk factor for cardiovascular disease (CVD) and mortality. | 28811734 |
| Inflammation, AKAP4 protein, human | Altered Intercellular Communication | We investigated whether aerobic exercise training (AEXT) affects African Americans with high inflammation (HI) the same way it does African Americans with low inflammation (LI) in terms of CVD risk factors. | 28811734 |
| Inflammation | Altered Intercellular Communication | This may indicate that, in African Americans with high inflammation, AEXT alone may not be enough to reap the same benefits as their low-inflammation peers in terms of CVD risk modification. | 28811734 |
| Sick Sinus Syndrome, Dacryoadenitis, Thyroid associated opthalmopathies, Orbital Pseudotumor | Altered Intercellular Communication | This is a retrospective case description of a single female patient found to have concomitant bilateral silent sinus syndrome, bilateral thyroid eye disease, unilateral dacryoadenitis, and idiopathic orbital inflammation that presented as progressive unilateral right-sided proptosis. | 28812921 |
| Aneurysm, Inflammation, Traumatic injury, Mobius II syndrome | Altered Intercellular Communication | Although the exact etiology is not known, inflammation, trauma, degenerative changes, and congenital weakness of venous wall have all been proposed as causes of venous aneurysms. | 28813774 |
| Inflammation, Tumor necrosis, Endothelial dysfunction | Altered Intercellular Communication | The biomarkers were representative of several biologic processes: apoptosis (soluble Fas), inflammation (soluble tumor necrosis factor receptor 1, interleukin 6, interleukin 8) and endothelial dysfunction, (angiopoietin 1, angiopoietin 2, and soluble vascular cell adhesion molecule 1). | 28814331 |
| Inflammation | Altered Intercellular Communication | The prognostic role of the neutrophil-to-lymphocyte ratio (NLR) and the eosinophil-to-lymphocyte ratio (ELR) as potential markers of inflammation has already been discussed. | 28814353 |
| Inflammation | Altered Intercellular Communication | Unlike eosinophilic inflammation, the inflammatory patterns seen in noneosinophilic CRSwNP are still poorly understood. | 28814353 |
| Inflammation, Rheumatoid Arthritis | Altered Intercellular Communication | Calprotectin as a marker of inflammation in patients with early rheumatoid arthritis. | 28814431 |
| Hypertension, CTCAE, Myelolipoma of adrenal gland, "Pituitary-dependent Cushings disease", Diabetes Mellitus | Altered Intercellular Communication | In this article, hormonal evaluation in a middle-aged woman with diabetes, hypertension and incidentally discovered unilateral adrenal myelolipoma revealed underlying subclinical Cushing's disease. | 28814582 |
| ARCN1 gene, Inflammation | Altered Intercellular Communication | Platelets may actively participate in inflammation in COPD. | 28814854 |
| Fatty Liver Disease, Necrosis with inflammation | Altered Intercellular Communication | This cohort was 51% females, mean age 60 years (25/82), 67% pretreated, 70% associated NASH, 67% with severe necro-inflammation (severity score 3-Fibromax), 37% with comorbidities, 10.4% with Child Pugh A6, 0.5% B7. | 28816020 |
| Neurodegenerative Disorders, Inflammation, Nerve Degeneration, "Alzheimers Disease", Data types - Address, Transient Ischemic Attack | Altered Intercellular Communication | Alzheimer's disease (AD) is a severe neurodegenerative brain disorder characterized by beta-amyloid plaques, Tau pathology, inflammation, neurodegeneration, and cerebrovascular dysfunction. | 28816110 |
| Dacryoadenitis | Altered Intercellular Communication | The role of biopsy in lacrimal gland inflammation: A clinicopathologic study. | 28816552 |
| Dacryoadenitis | Altered Intercellular Communication | To determine the causes of lacrimal gland inflammation based on histopathology and systemic evaluation. | 28816552 |
| Inflammation, Dacryoadenitis, Granulomatosis, Malignant myoepithelioma, Lipogranuloma, Fibrosis Assessment, Eosinophilic granulomatosis with polyangiitis, Lymphoma, Granulomatosis with polyangiitis, LACRIMAL INFLAMMATION, "Sjogrens Syndrome", Systemic Vasculitis | Altered Intercellular Communication | The histopathologic findings of the 60 patients showed that 37 (61.7%) had identifiable types of lacrimal inflammation including 10 with Sjogren's syndrome, seven with sarcoidal reaction, six with feature of granulomatosis with polyangiitis (formerly known as Wegener's granulomatosis), five with lymphoma, two with sclerosing inflammation, two with IgG4-related dacryoadenitis, and one patient each with infectious dacryoadenitis, myoepithelial carcinoma, xanthogranuloma, eosinophilic angiocentric fibrosis, and eosinophilic allergic granulomatous nodule. | 28816552 |
| Sore to touch, Dacryoadenitis, Edema, Erythema | Altered Intercellular Communication | We recommend that in patients presenting with lacrimal gland inflammation (i.e., erythema, edema, tenderness) in which the specific diagnosis cannot be made clinically and on imaging, biopsy is warranted for accurate diagnosis and appropriate treatment. | 28816552 |
| Sensorineural Hearing Loss (disorder), Arachnoiditis, Jugular Foramen Schwannoma | Altered Intercellular Communication | The aim of this case report was to present the excision of a large jugular foramen schwannoma via the retrosigmoid approach and to describe the improvement of sensorineural hearing loss related to arachnoid inflammations due to chronic arachnoiditis after suboccipital craniectomy. | 28816700 |
| Sepsis | Altered Intercellular Communication | Sepsis presents with similar profiles in adult and pediatric patients, characterized by enhanced inflammatory hormonal response and by repressed innate immunity, metabolism, and myocardial contractility. | 28816920 |
| Gastrointestinal inflammation | Altered Intercellular Communication | Furthermore, the small bowel transit time may not be affected by the grade of small intestinal inflammation. | 28816962 |
| Toxic effect, Inflammatory disease of mucous membrane, Febrile Neutropenia, CTCAE | Altered Intercellular Communication | The most common dose-limiting toxicities were febrile neutropenia and mucosal inflammation. | 28817190 |
| Inflammation, Primary malignant neoplasm, Obesity | Altered Intercellular Communication | Young Adult Risk Factors for Cancer: Obesity, Inflammation, and Sociobehavioral Mechanisms. | 28818242 |
| Inflammation, Obesity | Altered Intercellular Communication | After adjusting for these behavioral variables, sex, and race disparities in obesity and excess inflammation in blacks diminished, whereas the adolescent SES disparity in obesity remained. | 28818242 |
| Inflammation, Obesity | Altered Intercellular Communication | Behavioral factors associated with higher risks of obesity and inflammation differed, with the exception of fast food consumption, a risk factor for both. | 28818242 |
| Inflammation, Osteoporosis, Chronic disease | Altered Intercellular Communication | Inflammation may contribute to osteoporosis, as it does to many other chronic diseases. | 28819125 |
| Inflammation, Cerebrovascular accident | Altered Intercellular Communication | A Preliminary Investigation of the Association of Sleep With Inflammation and Oxidative Stress Biomarkers and Functional Outcomes After Stroke Rehabilitation. | 28819157 |
| Inflammation, Cerebrovascular accident | Altered Intercellular Communication | This study examined the association of sleep with inflammation and oxidative stress biomarkers, and with functional outcomes, after stroke rehabilitation. | 28819157 |
| Seizures, Inflammation, Hemorrhagic, Cavernous Hemangioma of Brain | Altered Intercellular Communication | Plasma Biomarkers of Inflammation Reflect Seizures and Hemorrhagic Activity of Cerebral Cavernous Malformations. | 28819935 |
| Intraocular inflammation | Altered Intercellular Communication | Intraocular inflammation developed in the fellow eye and SO was suspected, which was confirmed by characteristic findings seen on fluorescein angiography. | 28820164 |
| Inflammation | Altered Intercellular Communication | Although he responded well initially, he had recurrent inflammation and paradoxical worsening. | 28820170 |
| Inflammation | Altered Intercellular Communication | Training-induced changes in inflammation and oxidative stress status correlated with favorable improvements in semen parameters, sperm DNA integrity, and pregnancy rate (P < 0.05). | 28820950 |
| Inflammation, Pseudolymphoma | Altered Intercellular Communication | Five cases (three men, two women; age, 40-80 years) had restricted proliferations of atypical/monotypic IgG4+ plasma cells in a background of reactive lymphoid hyperplasia or inflammation. | 28821195 |
| Airway structure | Altered Intercellular Communication | Genetic and epigenetic susceptibility of airway inflammation to PM2.5 in school children: new insights from quantile regression. | 28821285 |
| Airway structure | Altered Intercellular Communication | The fractional concentration of exhaled nitric oxide (FeNO) is a biomarker of airway inflammation that has proved to be useful in investigations of genetic and epigenetic airway susceptibility to ambient air pollutants. | 28821285 |
| Acute Kidney Injury, CTCAE, Inflammation, Kidney Failure, Acute | Altered Intercellular Communication | Inflammation is a key component of both acute kidney injury (AKI) and response to cardiopulmonary bypass. | 28821332 |
| Hemorrhage, Chronic inflammation, Neoplasms, Myxoma, Hemosiderosis | Altered Intercellular Communication | Although microscopic examinations revealed enlarged vessels, hemorrhages and hemosiderosis in the left part and high cellularity with chronic inflammation in the right part, spindle-shaped cells in a loose myxoid stroma were observed in both parts of the tumor, consistent with the diagnosis of myxoma. | 28822084 |
| Inflammation, Malnutrition, Cachexia | Altered Intercellular Communication | Nineteen fulfilled the ESPEN basic definition, of which 10 had disease-related malnutrition with inflammation and 9 without inflammation, and 20 had cachexia. | 28822255 |
| Communicable Diseases | Altered Intercellular Communication | Intensive exercise modifies airway inflammation and infection susceptibility. | 28822267 |
| Airway structure | Altered Intercellular Communication | Dysregulation of the TNF-a/IL-1ra balance in EBC and nasal secretions from athletes may reflect the presence of airway inflammation induced by repeated strenuous exercise. | 28822267 |
| Inflammation | Altered Intercellular Communication | Inflammation or lymphatic disruption at the site of cannulation can cause the formation of lymphoceles, leading to the patient's discomfort and possibly necessitating intervention. | 28822659 |
| Communicable Diseases, Inflammation | Altered Intercellular Communication | Serum C-reactive protein (CRP) increases and albumin decreases in patients with inflammation and infection. | 28823374 |
| Pancreatitis | Altered Intercellular Communication | The CRP/albumin ratio is a novel but promising, easy-to-measure, repeatable, non-invasive inflammation-based prognostic score in acute pancreatitis. | 28823374 |
| Inflammation, Complement and Coagulation Cascade | Altered Intercellular Communication | Fibrinogen is a crucial role in coagulation cascade and inflammation. | 28823490 |
| Inflammation, Brain Injuries, Subarachnoid Hemorrhage, Aneurysmal, ASAH1 gene | Altered Intercellular Communication | We clarified whether serum MIF could be used as a marker of inflammation, brain damage and outcome after aneurysmal subarachnoid hemorrhage (aSAH). | 28823650 |
| Inflammation, Brain Injuries, ASAH1 gene | Altered Intercellular Communication | Serum MIF provides information about inflammation, brain injury severity and outcome after aSAH, which can be useful as a complement to clinical data. | 28823650 |
| Inflammation, Progranulins, GRN wt Allele | Altered Intercellular Communication | GP88 (progranulin; PGRN) is a secreted 88kDa glycosylated protein, with important functions, including inflammation and tumorigenesis. | 28823651 |
| Inflammation | Altered Intercellular Communication | The increased levels of the soluble forms of the two IL-1 receptors IL-1R1 and IL-1R2 suggest the need to dampen IL-1-mediated inflammation at the tissue level. | 28823915 |
| Inflammation, Malignant Neoplasms | Altered Intercellular Communication | Histological examination is necessary for the exclusion of malignancy and chronic inflammation. | 28824310 |
| Retinal Degeneration, Dystrophy, Intraocular inflammation, Chickenpox, Autoimmune retinopathy | Altered Intercellular Communication | Autoimmune retinopathy was suspected on the basis of the clinical presentation, electrophysiology, absence of fundus lesions, retinal degenerations or dystrophies, or intraocular inflammation and temporal association with varicella infection. | 28825165 |
| Inflammation, Data types - Address | Altered Intercellular Communication | To address in older subjects (i) the relationships between AD pathology and MIF plasma and cerebrospinal fluid (CSF) levels; and (ii) to investigate whether increased MIF-related systemic and CNS inflammation is associated with clinical disease progression. | 28826184 |
| Data types - Address, Trauma, Nervous System | Altered Intercellular Communication | Our study provides evidence that MIF-related inflammation is related to amyloid pathology, tau hyperphosphorylation, and neuronal injury at the early clinical stages of AD. | 28826184 |
| Inflammation | Altered Intercellular Communication | These results suggested impaired resolution of inflammation in the absence of Tet2 both in vitro and in vivo. | 28826859 |
| Inflammation, Myeloid | Altered Intercellular Communication | Our results show that Tet2 restrains inflammation in murine MPhs and mice, raising the possibility that loss of TET2 function in MPhs may alter the immune environment in the large elderly population with TET2-mutant CHIP and in TET2-mutant myeloid cancer patients. | 28826859 |
| vascular inflammations, Psoriasis | Altered Intercellular Communication | The relationship between duration of psoriasis, vascular inflammation, and cardiovascular events. | 28826925 |
| vascular inflammations, Psoriasis | Altered Intercellular Communication | Whether psoriasis duration affects risk of vascular inflammation and MACEs has not been well characterized. | 28826925 |
| vascular inflammations | Altered Intercellular Communication | Vascular inflammation by fludeoxyglucose F 18 positron emission tomography/computed tomography was significantly associated with disease duration (b = 0.171, P = .002). | 28826925 |
| Inflammation, vascular inflammations, Psoriasis, Vascular Diseases | Altered Intercellular Communication | We found detrimental effects of psoriasis duration on vascular inflammation and MACE, suggesting that cumulative duration of exposure to low-grade chronic inflammation may accelerate vascular disease development and MACEs. | 28826925 |
| Rhabdomyolysis, Hypothyroidism | Altered Intercellular Communication | Initial laboratory testing showed elevated thyroid stimulating hormone (TSH) and creatine kinase (CK) levels, indicating uncontrolled hypothyroidism with associated rhabdomyolysis. | 28827517 |
| Gastric Adenocarcinoma, Primary malignant neoplasm | Altered Intercellular Communication | Systemic Inflammation Response Index (SIRI), cancer stem cells and survival of localised gastric adenocarcinoma after curative resection. | 28828692 |
| Refractory anemias | Altered Intercellular Communication | Thus, a close relation of MMP-3 with PAs and PVR indicate that rise in PAs in patients with RA was ascribed to increase in PVR due to underlying systemic inflammation-mediated pulmonary vascular remodeling. | 28828748 |
| Overhydration, Inflammation, Endothelial dysfunction, Chronic Kidney Diseases | Altered Intercellular Communication | Extracellular overhydration linked with endothelial dysfunction in the context of inflammation in haemodialysis dependent chronic kidney disease. | 28829810 |
| Inflammation, Ischemic stroke | Altered Intercellular Communication | Elevated neutrophil to lymphocyte ratio (NLR) has been reported as a marker for chronic inflammation, associated with poor prognosis in ischemic stroke patients, but there has been no study that investigated its association with ischemic stroke risk. | 28829826 |
| Inflammation, Neoplasms | Altered Intercellular Communication | Known neoplasm, inflammation or poor imaging were excluded. | 28829975 |
| Inflammation | Altered Intercellular Communication | Compared with those in patients with STEMI, differentially expressed microRNAs in controls and patients with SA or NSTE-ACS were involved in inflammation, protein phosphorylation, and cell adhesion. | 28830367 |
| Kidney Failure, Chronic, Inflammation, Chronic Kidney Diseases, Ulcerative Colitis | Altered Intercellular Communication | We hypothesized that a reversal of the physiological stiffness gradient, previously reported in end-stage renal disease, begins in the early stages of chronic kidney disease (CKD) and that chronic inflammation produces a different arterial phenotype in patients with ulcerative colitis (UC). | 28830726 |
| Inflammation, Ulcerative Colitis | Altered Intercellular Communication | In patients with UC, the stiffness of both elastic and muscular arteries is increased as a consequence of inflammation. | 28830726 |
| Tumor necrosis, Inflammation, COL4A2 wt Allele | Altered Intercellular Communication | The results suggest that tumor necrosis factor-mediated inflammation could be associated with vascular changes preceding ICH. | 28830973 |
| Pain Distress Question, Inflammation, Pruritus | Altered Intercellular Communication | We applied a systems-based, translational approach to predict, discover, and characterize mediators of pain and itch that are regulated by diet and inflammation. | 28831021 |
| ACSM3 gene, Inflammation, Subarachnoid Hemorrhage, Aneurysmal, Tissue injury | Altered Intercellular Communication | A matricellular protein galectin-3 is involved in tissue injury and inflammation, but the role of galectin-3 remains unclear in aneurysmal subarachnoid hemorrhage (SAH). | 28831694 |
| Inflammation, Brain Injuries, Cerebral Infarction, Vasospasm | Altered Intercellular Communication | The findings suggest that plasma galectin-3 levels on days 1-3 would be a useful biomarker for predicting subsequent development of delayed cerebral infarction and eventual poor outcome and provide a new candidate, which may mediate between post-SAH early brain injury or inflammation and delayed cerebral infarction without vasospasm. | 28831694 |
| Inflammation | Altered Intercellular Communication | Chronic inflammation is the usual cause, but acute trigger finger following partial tendon laceration has also been described. | 28832206 |
| Inflammation, Traumatic injury, Malignant Neoplasms | Altered Intercellular Communication | The differential diagnosis is extensive, including: malignancy, trauma, inflammation of the urinary tract, and stones. | 28832315 |
| ARCN1 gene, Inflammation, Chronic Obstructive Airway Disease | Altered Intercellular Communication | Long-term treatment with budesonide/formoterol attenuates circulating CRP levels in chronic obstructive pulmonary disease patients of group D. The systemic inflammation is associated with clinical outcome and mortality in chronic obstructive pulmonary disease (COPD) patients. | 28832630 |
| Inflammation, Wheezing, Respiratory Failure | Altered Intercellular Communication | Bronchial wheezing predicts inflammation and respiratory failure in fire smoke victims. | 28832892 |
| Inflammation, Respiratory Failure, Pulmonary Dysfunction | Altered Intercellular Communication | In victims of fire smoke inhalation, pulmonary wheezing predicts inflammation, pulmonary dysfunction, respiratory failure, and need for intensive care. | 28832892 |
| Inflammation, Diabetes Mellitus | Altered Intercellular Communication | The role of inflammation in diabetes development is not fully elucidated. | 28834086 |
| Conjunctivitis | Altered Intercellular Communication | Their symptoms, conjunctival inflammation, corneal staining, and visual acuity were compared before and after treatment. | 28834819 |
| Inflammatory abnormality of the eye | Altered Intercellular Communication | After epithelial debridement and placement of the PKS for 5 +- 3.7 days, all patients reported significant relief of symptoms, rapid corneal epithelialization, and reduction of ocular surface inflammation. | 28834819 |
| Inflammation, Fibrosis Assessment | Altered Intercellular Communication | We found an association between a reduction in the fibrosis stage and continuous glucocorticoid medication, as well as lowered scores of inflammation at last biopsy. | 28834875 |
| Inflammation, Cardiovascular Diseases | Altered Intercellular Communication | In recent years, lymphocyte-to-monocyte ratio (LMR) has become a novel indirect marker of inflammation, which has been demonstrated to be associated with poor prognosis of oncology and cardiovascular disease. | 28834908 |
| Peripheral Arterial Diseases | Altered Intercellular Communication | Endothelial Cell Inflammation and Antioxidant Capacity are Associated With 6-Minute Walk Performance in Patients With Symptomatic Peripheral Artery Disease. | 28835113 |
| Inflammation, Peripheral Arterial Diseases | Altered Intercellular Communication | We determined whether 6-minute walk total distance and pain-free distance were associated with circulating biomarkers of antioxidant capacity and inflammation and with cultured endothelial cell inflammation, oxidative stress, and apoptosis in 251 patients with symptomatic peripheral artery disease (PAD). | 28835113 |
| Inflammation, Allergy - Charge Type Reason, Infection, Edema, Abnormal renal function, Endocrine System Diseases, Traumatic injury, Primary Hypothyroidism | Altered Intercellular Communication | Common causes of periorbital edema include infections, inflammation, trauma, allergy, kidney or cardiac dysfunction, and endocrine disorders such as primary hypothyroidism. | 28835258 |
| Inflammation, Depression, CTCAE | Altered Intercellular Communication | The role of inflammation in the pathophysiology of depression remains unknown; however, the symptom cluster of sickness behavior is more clearly related to inflammation. | 28835295 |
| Amyotrophic Lateral Sclerosis | Altered Intercellular Communication | Our results indicate that hormonal factors may be important etiologic factors in ALS; however, a full understanding requires further investigation. | 28835399 |
| Malignant Neoplasms | Altered Intercellular Communication | The serum macrophage inhibitory cytokine-1 (MIC-1) levels are elevated in some inflammatory conditions and cancers. | 28835660 |
| Stomach Carcinoma | Altered Intercellular Communication | The prognostic significance of inflammation-based markers in patients with recurrent gastric cancer. | 28836056 |
| Inflammation, Hypertension, CTCAE | Altered Intercellular Communication | Masked hypertension (MHTN) and lack of nocturnal dipping in blood pressure (BP) have been linked to the state of inflammation. | 28836174 |
| Inflammation, Hypoalbuminemia, Failure (biologic function) | Altered Intercellular Communication | Early and persistent systemic inflammation and high NPWT output were associated with hypoalbuminemia, which was an independent predictor of failure to achieve PFC. | 28837537 |
| Communicable Diseases, Inflammation, Immune System Diseases, GDC Comorbidity Terminology | Altered Intercellular Communication | Elderly long-term care residents often exhibit a myriad of risk factors for immune dysfunction, including chronic inflammation and multiple comorbid conditions, which undoubtedly contribute to their enhanced susceptibility to infection. | 28838148 |
| Inflammation, Carcinoma of lung, Neoplasms | Altered Intercellular Communication | High neutrophil-to-lymphocyte ratio (NLR) and platelet-to-lymphocyte ratio (PLR) are markers of host inflammation and associated with worse overall survival (OS) in several tumor types, but have not been analysed extensively in lung cancer in the era of immunotherapy. | 28838390 |
| vascular inflammations, Vasospasm | Altered Intercellular Communication | In conclusion, our results suggest that EPA and DHA pretreatment may be beneficial to counteract graft vasospasm and vascular inflammation in SV which are important factors in graft failure development. | 28838848 |
| Inflammation, Atherosclerosis | Altered Intercellular Communication | Inflammation is suggested to be a central feature of atherosclerosis, particularly among smokers. | 28838917 |
| Inflammation | Altered Intercellular Communication | Acute and chronic exposure to tobacco smoking is associated with inflammation, as quantified by both GlycA and high-sensitivity C-reactive protein. | 28838917 |
| Inflammation | Altered Intercellular Communication | This indicates that work stress is associated altered metabolic profile, increased systemic inflammation, and, in men, poorer liver function, which is a marker of high alcohol consumption. | 28839130 |
| Inflammation | Altered Intercellular Communication | Ultrapure dialysis water obtained with additional ultrafilter may reduce inflammation in patients on hemodialysis. | 28840494 |
| Inflammation, Anemia, Atherosclerosis | Altered Intercellular Communication | Inflammation is a potent trigger of atherosclerosis and a pathogenetic factor in anemia, increasing mortality and morbidity in dialysis patients. | 28840494 |
| Bronchitis | Altered Intercellular Communication | Asthma is a syndrome of chronic bronchial inflammation and airway remodelling. | 28840844 |
| Inflammation, Tumor necrosis | Altered Intercellular Communication | Nuclear factor-kappa B dimers are encoded by nuclear factor-kappa B genes and regulate transcription of several crucial proteins of inflammation such as tumour necrosis factor-alpha. | 28840846 |
| Inflammation, Impaired cognition | Altered Intercellular Communication | Evidence indicates that alcohol binges induce peripheral inflammation and an exacerbated neuroimmune response that may participate in alcohol-induced cognitive/behavioral dysfunctions. | 28840951 |
| Inflammation, Thrombosis, Injury of cardiac valve, Platelet aggregation test result | Altered Intercellular Communication | Platelet aggregation, thrombosis formation, and inflammation are the main causes of cardiac injury during PCI. | 28841229 |
| Inflammation, Blood Coagulation Disorders | Altered Intercellular Communication | Biomarkers of coagulopathy and inflammation, platelet counts, FDP, PT, a2-PI, AT III, plasminogen, and C-reactive protein were significantly different between the two groups. | 28841902 |
| Sepsis, Inflammation, Observation Method - Coagulation, Kidney Failure, Acute | Altered Intercellular Communication | Particularly, sTM was an independent predictive biomarker for the development of AKI that outperformed other coagulation and inflammation biomarkers as well as organ function in patients with sepsis. | 28841902 |
| Pain Distress Question, Hyperplastic Polyp, Inflammation | Altered Intercellular Communication | No difference in the proportion of patients with moderate/severe pain was found between MP/placebo groups at 24 hours (67% and 74%, kh2 = .2, P = .63, odds ratio = .7, 95% confidence interval = .2-2.8) or at 48 hours (57% and 68%, kh2 = .5, P = .46, odds ratio = .6, 95% confidence interval = .2-2.3), and no difference between groups in postoperative sensitization was found (P > .4) despite reduced preoperative intra-articular inflammation (IL-6) in the MP group versus placebo (median change in IL-6 = -70 pg/mL, interquartile range = -466 to 0 vs. 32 pg/mL, interquartile range = -26 to 75, P = .029). | 28842370 |
| Inflammation, DGCR2 gene | Altered Intercellular Communication | However, whether inflammatory stimuli activate TonEBP in NP cells and whether TonEBP controls inflammation during IDD is unknown. | 28842479 |
| Inflammation | Altered Intercellular Communication | Transcription factor NFkB is a major regulatory component influencing mucosal inflammation. | 28842689 |
| Inflammation, Colorectal Carcinoma | Altered Intercellular Communication | Taken together, decreased expression of TNFAIP3 and its partners contribute to inflammation and up-regulation of apoptosis inhibitors that may create microenvironment for colorectal cancer. | 28842689 |
| Inflammation, Dislocations | Altered Intercellular Communication | The analysis consisted of determining whether the LHB was present, the extrinsic tendon abnormalities (dislocation, tendon coverage) and intrinsic abnormalities (fraying, inflammation, degeneration). | 28842745 |
| ARCN1 gene, Inflammation, Arterial Stiffness, Heart failure | Altered Intercellular Communication | In COPD patients, heart failure (HF) is associated with worse conditions such as inflammation, arterial stiffness, and increased risk mortality. | 28844547 |
| ARCN1 gene, Chronic Obstructive Airway Disease, Airway Obstruction | Altered Intercellular Communication | Chronic obstructive pulmonary disease (COPD) is a chronic inflammatory condition characterized by complex lesions of the lungs and other organs as well as a progressive obstruction of the airway. | 28844547 |
| Toxic effect | Altered Intercellular Communication | It was suggested an inflammation-derived oxidative stress and cytokine-dependent toxicity role in the nigrostriatal pathway degeneration and hasten progression of disease. | 28844731 |
| Inflammation, Cardiovascular Diseases | Altered Intercellular Communication | Experimental and clinical data suggest that reducing inflammation without affecting lipid levels may reduce the risk of cardiovascular disease. | 28845751 |
| Airway structure, Asthma | Altered Intercellular Communication | Fractional exhaled nitric oxide (FeNO) is a non-invasive method used to reveal the eosinophilic inflammation of airway and to diagnose and manage asthma. | 28846444 |
| Tumor necrosis, Diabetes Mellitus | Altered Intercellular Communication | Interleukin 6 (IL-6) and Tumor Necrosis Factor a (TNF-a) Single Nucleotide Polymorphisms (SNPs), Inflammation and Metabolism in Gestational Diabetes Mellitus in Inner Mongolia. | 28846666 |
| Gestational Diabetes, Inflammation | Altered Intercellular Communication | CONCLUSIONS TNF-a -857C/T SNP, hs-CRP, IL-6, IL-8, and IL-6/IL-10 were associated with GDM in women from Inner Mongolia, as was serious inflammation and disordered lipid and glucose metabolisms. | 28846666 |
| Inflammation, Premature Obstetric Labor | Altered Intercellular Communication | Decidual senescence has been considered a mechanism of disease for spontaneous preterm labor in the absence of severe acute inflammation. | 28847437 |
| Cerebrovascular Disorders, Arteritis | Altered Intercellular Communication | Increasing data supports the role of bacterial inflammation in adverse events of cardiovascular and cerebrovascular diseases. | 28847664 |
| Communicable Diseases, Inflammation, Bacterial Infections, CRNKL1 wt Allele | Altered Intercellular Communication | Patients with ACLF and bacterial infections (either at diagnosis or during follow-up) showed higher grade of systemic inflammation at diagnosis of the syndrome, worse clinical course (ACLF 2-3 at final assessment: 47% vs 26%; p<0.001) and lower 90-day probability of survival (49% vs 72.5%;p<0.001) than patients with ACLF without infection. | 28847867 |
| Inflammation | Altered Intercellular Communication | They are severe and associated with intense systemic inflammation, poor clinical course and high mortality. | 28847867 |
| Chronic sinusitis | Altered Intercellular Communication | Lower Airway Inflammation in Eosinophilic Chronic Rhinosinusitis as Determined by Exhaled Nitric Oxide. | 28848094 |
| Airway structure, Craniosynostosis | Altered Intercellular Communication | ECRS patients had lower airway inflammation as revealed by an elevated FeNO, which was parallel to the Lund-Mackay CT scores. | 28848094 |
| Inflammation, Traumatic injury, Alcohol-Induced Disorders | Altered Intercellular Communication | Alcohol-induced immune-suppression during acute inflammation (trauma) was linked to nuclear factor-kappaB (NF-kB). | 28848184 |
| ARCN1 gene, Inflammation, Chronic Obstructive Airway Disease | Altered Intercellular Communication | The definition of new markers of local and systemic inflammation of chronic obstructive pulmonary disease (COPD) is one of the priority directions in the study of pathogenesis and diagnostic methods improvement for this disease. | 28848245 |
| ARCN1 gene, Inflammation | Altered Intercellular Communication | The findings suggest a pathogenetic role of the investigated soluble molecules of the COPD development and allow considering the content of sCD8, sCD25, and sHLA-I-CD8 molecules as additional novel systemic and endobronchial markers of the progression of chronic inflammation of this disease. | 28848245 |
| Inflammation, ovarian neoplasm, Ascites | Altered Intercellular Communication | Markers of Oxidative Stress and Inflammation in Ascites and Plasma in Patients with Platinum-Sensitive, Platinum-Resistant, and Platinum-Refractory Epithelial Ovarian Cancer. | 28848618 |
| Inflammation, Ascites, Platinum-Sensitive Ovarian Carcinoma, Platinum-Resistant Ovarian Carcinoma | Altered Intercellular Communication | To determine the behavior of markers of oxidative stress and inflammation in plasma and ascites fluid in patients with platinum-sensitive, platinum-resistant, and platinum-refractory EOC. | 28848618 |
| Have Autoimmune or Inflammatory Condition, Connective Tissue Diseases, Immune System Diseases, Lupus Erythematosus | Altered Intercellular Communication | Systemic lupus erythematosus is a connective tissue disease characterized by autoimmune inflammation, which leads to specific and nonspecific immune disorders with the formation of various autoantibodies by activated B cells. | 28849060 |
| Traumatic injury | Altered Intercellular Communication | The present study confirmed the high expression of miR-24 in peripheral blood during AP, suggesting that miR-24 might have an intercellular communication role contributing to the AP-associated distant organ injury. | 28849189 |
| Inflammation | Altered Intercellular Communication | Disadvantaged social statuses, such as being female, poor, or a minority, are associated with increased psychosocial stress and elevated circulating concentrations of C-reactive protein, a biomarker of chronic inflammation and indicator of cardiovascular health. | 28849408 |
"
| Inflammation, Osteoporosis, Joint structure of shoulder region, Fracture, Arthritis | Altered Intercellular Communication | Exclusion criteria were: glenohumeral
arthritis or other inflammation, fracture around the shoulder joint,
elderly patients with osteoporosis. | 28850207 | "
| Inflammation | Altered Intercellular Communication | The long-term gastric inflammation and associated-damage to the gastric mucosa might play a role in such associations. | 28850590 |
| Heart failure | Altered Intercellular Communication | We observed a response of advanced heart failure patients to surgery orchestrated into stages: first, activation of the innate immune response, followed by anti-inflammation, and finally reparative processes such as mitosis, coagulation, and apoptosis. | 28851355 |
| Inflammation, Lipids abnormal | Altered Intercellular Communication | The results of proteomic analysis were consistent with involvement of inflammation, lipid abnormalities, hemostasis and extracellular matrix remodeling in CAS. | 28851525 |
| Sarcoma, Inflammation | Altered Intercellular Communication | The presence of systemic inflammation has been reported to be associated with poor prognosis in patients with soft tissue sarcoma (STS). | 28851899 |
| Degenerative polyarthritis, Pain Distress Question, Inflammation, malvidin | Altered Intercellular Communication | Malvidin attenuates pain and inflammation in rats with osteoarthritis by suppressing NF-kB signaling pathway. | 28852776 |
| Pain Distress Question, Inflammation | Altered Intercellular Communication | Our findings suggest that Malvidin significantly attenuates the OA-induced pain and inflammation by inhibiting NF-kB signaling pathway and suppressing pro-inflammatory cytokine expression and chondrocyte apoptosis. | 28852776 |
| Inflammation | Altered Intercellular Communication | However, since the mesh is placed in close contact with the spermatic cord, mesh-induced inflammation may affect its structures, possibly resulting in impaired fertility. | 28852860 |
| Liver carcinoma | Altered Intercellular Communication | The preoperative globulin-to-albumin ratio, a novel inflammation-based prognostic system, predicts survival after potentially curative liver resection for patients with hepatocellular carcinoma. | 28853157 |
| Inflammation, Structure of pectineus muscle | Altered Intercellular Communication | Follow-up MRI at two weeks demonstrated a dramatic reduction in the inflammation of the pectineus. | 28853599 |
| Communicable Diseases, Inflammation, Abnormal degeneration, Laceration | Altered Intercellular Communication | In this setting, chronic inflammation and lacerations associated with history of human papillomavirus (HPV) infection may induce a high risk of malignant degeneration in the long term. | 28853678 |
| Inflammation, Primary malignant neoplasm, Neoplasms | Altered Intercellular Communication | Inflammation in the tumour microenvironment mediated by interleukin 1b is hypothesised to have a major role in cancer invasiveness, progression, and metastases. | 28855077 |
| Inflammation, Malignant Head and Neck Neoplasm, Atherosclerosis | Altered Intercellular Communication | Human papillomavirus (HPV) is found in nearly half of head and neck cancers and is associated with inflammation and atherosclerosis. | 28855164 |
| Hypogonadism, Osteopenia, Fracture | Altered Intercellular Communication | Although hypogonadism is a risk factor for bone loss and fractures, the different etiopathophysiology and hormonal profile of classical and obesity-induced hypogonadism may lead to differences in musculoskeletal profile. | 28856390 |
| ARCN1 gene, Inflammation, Cardiovascular Diseases, Chronic Obstructive Airway Disease, Endothelial dysfunction, Arterial Stiffness | Altered Intercellular Communication | Chronic obstructive pulmonary disease (COPD) is associated with endothelial dysfunction, arterial stiffness and systemic inflammation, which are linked to increased cardiovascular disease risk. | 28857336 |
| Arterial Stiffness, Inflammation, Dyspnea, ARCN1 gene | Altered Intercellular Communication | Eight weeks of periodized aerobic training did not improve endothelial function, arterial stiffness or systemic inflammation in COPD, despite improvements in aerobic capacity, blood pressure and dyspnoea. | 28857336 |
| Inflammatory Bowel Diseases, Inflammation | Altered Intercellular Communication | Dietary elimination can improve symptoms and endoscopic inflammation in patients with IBD. | 28858071 |
| Kallmann Syndrome, Anosmia, Sense of smell impaired | Altered Intercellular Communication | Kallmann syndrome (KS) is a genetic gonadotropin-releasing hormone deficiency associated with hyposmia or anosmia and characterized by various modes of inheritance. | 28858133 |
| glycation, vascular inflammations, Endothelial dysfunction | Altered Intercellular Communication | Amyloidogenic medin induces endothelial dysfunction and vascular inflammation through the receptor for advanced glycation endproducts. | 28859297 |
| Inflammation | Altered Intercellular Communication | These patients, despite having no signs of significant inflammation, report an impact of disease similar to the non-remission patients. | 28859325 |
| Inflammation | Altered Intercellular Communication | Colchicine introduction and dose increase lead to significant reduction of clinical symptoms and inflammation. | 28859329 |
| Inflammation | Altered Intercellular Communication | Small proline-rich proteins (SPRR) are polypeptides that have recently been shown to contribute to epithelial biomechanical properties relevant in T-helper type 2 inflammation. | 28859701 |
| Inflammation, Arthritis | Altered Intercellular Communication | Synovial inflammation plays a critical role in the symptoms and structural progression of arthritis which leads to irreversible damage of the adjacent cartilage and bone. | 28860038 |
| Inflammation, Asthma | Altered Intercellular Communication | Fraction of exhaled nitric oxide (FeNO) provides information about chronic inflammation in asthma. | 28860527 |
| Refractory anemias, Inflammation, GDC AJCC Clinical Stage Terminology | Altered Intercellular Communication | Early intervention for controlling the inflammation associated with RA can play a significant role in preventing cardiac remodeling in ACS patients. | 28860666 |
| Inflammation, Impaired cognition | Altered Intercellular Communication | Furthermore, inflammation markers were significantly correlated with muscle strength, walking distance and cognitive impairment. | 28860729 |
| Inflammation, Fibrosis Assessment | Altered Intercellular Communication | Higher values of IP-10 were associated with increasing stages of fibrosis (P<0.01) and higher grades of inflammation (P=0.02, P=0.07) assessed morphologically and noninvasively through FibroTest and ActiTest. | 28862188 |
| Inflammation, Aggressive behavior | Altered Intercellular Communication | The odontogenic keratocyst is known for its aggressiveness, high recurrence rate, and transformation of keratinized epithelia to nonkeratinized squamous epithelium for which inflammation has been suggested to be responsible. | 28862228 |
| Acromegaly | Altered Intercellular Communication | Reoperation for recurrent acromegaly has been associated with poor results, with hormonal control usually achieved in fewer than 50% of cases. | 28862548 |
| Inflammation, Aggressive behavior | Altered Intercellular Communication | These results indicate that low serum albumin levels correlate with increased parameter measures of HCC aggressiveness, in addition to their role as a monitor of systemic inflammation. | 28862714 |
| Kidney Failure, Chronic, Inflammation, Malnutrition | Altered Intercellular Communication | Sedentariness, high inflammation status and malnutrition are highly prevalent in end-stage kidney disease patients on maintenance hemodialysis (MHD). | 28862722 |
| Inflammation | Altered Intercellular Communication | Greater physical activity assessed by PAEE was associated with indicators of better nutritional and inflammation status. | 28862722 |
| Myocarditis | Altered Intercellular Communication | Multiple Cox regression analysis revealed perforin above the calculated cutoff point of 2.9 cells/mm2 as a strong predictor of impaired survival with a hazard ratio of 1.881 (95% confidence interval, 1.177-3.008; P=0.008), independent of left ventricular function and other myocardial inflammation markers (CD3, macrophage-1 antigen, leukocyte function-associated antigen-1, human leukocyte antigen-1, and intercellular cell adhesion molecule-1). | 28862949 |
| Plasmodium knowlesi, Inflammation, Malaria, Falciparum, physiopathological | Altered Intercellular Communication | Effects of Aging on Parasite Biomass, Inflammation, Endothelial Activation, Microvascular Dysfunction and Disease Severity in Plasmodium knowlesi and Plasmodium falciparum Malaria. | 28863470 |
| Tissue damage, Inflammation | Altered Intercellular Communication | NETosis is a host defense mechanism associated with inflammation and tissue damage. | 28863968 |
| Cerebral Amyloid Angiopathy, Vasculitis, Inflammation, Vasculitis, CTCAE | Altered Intercellular Communication | In amyloid b-related angiitis of the central nervous system (also called cerebral amyloid angiopathy-related inflammation), cerebral amyloid angiopathy occurs in association with primary vasculitis of small- and medium-sized leptomeningeal and cortical arteries. | 28864038 |
| Cerebral Amyloid Angiopathy, Inflammation, Hyperintensity of cerebral white matter on MRI | Altered Intercellular Communication | To avoid brain biopsy, clinicoradiological criteria (including clinical features due to inflammation-related uni/multifocal white matter hyperintensities) for the diagnosis of cerebral amyloid angiopathy-related inflammation have been validated recently. | 28864038 |
| Cerebral Amyloid Angiopathy | Altered Intercellular Communication | We report 3 cases with acute symptoms directly related to cerebral amyloid angiopathy in the presence of asymptomatic cerebral amyloid angiopathy-related inflammation hyperintensities on initial magnetic resonance imaging. | 28864038 |
| Cerebral Amyloid Angiopathy, Inflammation | Altered Intercellular Communication | Recognizing radiological features of cerebral amyloid angiopathy-related inflammation in patients with cerebral amyloid angiopathy is important because radiological isolated cerebral amyloid angiopathy-related inflammation may become symptomatic and immunosuppressive treatment is often effective in cerebral amyloid angiopathy-related inflammation, although optimal treatment regimen is yet unknown. | 28864038 |
| ARCN1 gene, Inflammation, Bronchiolitis | Altered Intercellular Communication | MicroRNA-218 acts by repressing TNFR1-mediated activation of NF-kB, which is involved in MUC5AC hyper-production and inflammation in smoking-induced bronchiolitis of COPD. | 28864214 |
| ARCN1 gene, Inflammation | Altered Intercellular Communication | As determined in the present investigation, population-based data indicate that smokers with COPD had serious airflow obstruction and inflammation, whereas smokers without COPD had mild airflow obstruction and inflammation. | 28864214 |
| ARCN1 gene, Inflammation, Bronchiolitis | Altered Intercellular Communication | In sum, our findings provide a mechanism by which miR-218 regulates CSE-induced MUC5AC hyper-production and inflammation by targeting TNFR1-mediated activation of NF-kB, indicating that overexpression of miR-218 may be a strategy against cigarette smoking-induced bronchiolitis in COPD. | 28864214 |
| Inflammation | Altered Intercellular Communication | Although high ferritin levels are associated with iron overload, it is known that ferritin is also an acute-phase reactant that may be elevated in conditions associated with acute and chronic inflammation. | 28864373 |
| Degenerative polyarthritis, Inflammation | Altered Intercellular Communication | These findings suggest that synovial inflammation is likely the result of joint structural abnormalities in established OA. | 28864651 |
| Communicable Diseases, Inflammation, Injury of integument | Altered Intercellular Communication | Skin injury affects millions of people via the uncontrolled inflammation and infection. | 28864782 |
| Inflammation, Autonomic nervous system disorders, Brain Damage, Chronic | Altered Intercellular Communication | Although correlations were weak and not significant, pupillary autonomic dysfunction is rather linked to chronic damage than to active inflammation or symptoms of autonomic dysfunction. | 28864843 |
| Inflammation, Esophageal Diseases, "Extra-osseous Ewings sarcoma | Altered Intercellular Communication | EoE was defined as the presence of symptoms of esophageal dysfunction with pathologically proven eosinophilic inflammation (>=15 eosinophils per high-power field [EOS/HPF]) unresponsive to reflux therapy. | 28865084 |
| Inflammation, Experimental Autoimmune Encephalomyelitis, MS gene | Altered Intercellular Communication | In multiple sclerosis (MS) and experimental autoimmune encephalomyelitis (EAE), inflammation is perpetuated by both infiltrating leukocytes and astrocytes. | 28865458 |
| Respiratory Distress Syndrome, Adult, Inflammation | Altered Intercellular Communication | In addition, extracellular histones correlated with an evident systemic inflammation detected in ARDS patients. | 28865478 |
| Respiratory Distress Syndrome, Adult, Inflammation, Liver damage | Altered Intercellular Communication | Extracellular histones in ARDS patients are excessively increased and may contribute to disease aggravation by inducing cellular damage and promoting systemic inflammation. | 28865478 |
| Carcinogenesis, Gastrointestinal inflammation | Altered Intercellular Communication | Dietary patterns affect systemic and local intestinal inflammation, which have been linked to colorectal carcinogenesis. | 28865736 |
| Inflammation, Colorectal Carcinoma | Altered Intercellular Communication | These findings suggest that diet-related inflammation might contribute to development of colorectal cancer, by suppressing the adaptive anti-tumor immune response. | 28865736 |
| Inflammation, Coronary heart disease, Choline Dehydrogenase, Mitochondrial | Altered Intercellular Communication | There has been conflicting results regarding the role of ferritin, a nonspecific marker of systemic inflammation, in the development of coronary heart disease (CHD). | 28865891 |
| Inflammation | Altered Intercellular Communication | The mechanisms may be attributed to immune suppression-triggered infection or immune overreaction-triggered aseptic inflammation. | 28866066 |
| Allergic sensitization, Inflammation, Asthma | Altered Intercellular Communication | With advancing age, patients with severe asthma are more obese, have greater airflow limitation, less allergen sensitization, and variable type 2 inflammation. | 28866107 |
| palladium, Inflammation, Intestinal infectious disease (disorder) | Altered Intercellular Communication | We explore the possibility that intestinal infections, and associated inflammation, place individuals at increased risk of PD by increasing alpha-synuclein levels and promoting the formation of alpha-synuclein aggregates that propagate in a prion-like fashion via the vagal nerve to the brainstem. | 28866688 |
| Inflammation, Electrocardiogram: myocardial infarction (finding), myocardial injury | Altered Intercellular Communication | Frequency of Cholesterol Crystals in Culprit Coronary Artery Aspirate During Acute Myocardial Infarction and Their Relation to Inflammation and Myocardial Injury. | 28867129 |
| Rupture, Inflammation | Altered Intercellular Communication | Cholesterol crystals (CCs) have been associated with plaque rupture through mechanical injury and inflammation. | 28867129 |
| Acute myocardial infarction, Inflammation, myocardial injury | Altered Intercellular Communication | This study evaluated the presence of CCs during acute myocardial infarction (AMI) and associated myocardial injury, inflammation, and arterial blood flow before and after percutaneous coronary intervention. | 28867129 |
| Communicable Diseases, Inflammation, Depression, CTCAE | Altered Intercellular Communication | High serum albumin levels may provide protection against depression through its defensive role in inflammation and infection. | 28867422 |
| Inflammation | Altered Intercellular Communication | Accumulation of large-scale mitochondrial DNA (mtDNA) deletions and chronic, subclinical inflammation are concomitant during skin aging, thus raising the question of a causal link. | 28867657 |
| Dermatitis | Altered Intercellular Communication | Mice displayed low amounts of large-scale deletions and a dramatic depletion of mtDNA in the epidermis and showed macroscopic signs of severe skin inflammation. | 28867657 |
| Respiratory chain dysfunction, Inflammation | Altered Intercellular Communication | Altogether, these data unraveled a previously unknown link between an imbalanced stoichiometry of the mitochondrial respiratory chain complexes and skin inflammation and suggest that severe respiratory chain dysfunction, as observed in few cells leading to a mosaic in aged tissues, might be involved in the development of chronic subclinical inflammation. | 28867657 |
| Data types - Address | Altered Intercellular Communication | Inflammation-related markers were associated with age, but not AD. | 28869479 |
| ACSM3 gene, Inflammation, Brain Injuries | Altered Intercellular Communication | Early brain injury (EBI) plays an important role in the pathophysiology of SAH, and inflammation is a major contributor to EBI. | 28869993 |
| ACSM3 gene, Inflammation | Altered Intercellular Communication | Inflammation is a widely studied topic in both experimental and clinical conditions; however, just a few clinical studies have focused primarily on the early inflammatory response after SAH, and detailed information about the association between the dynamics of early inflammatory response with main clinical characteristics is lacking. | 28869993 |
| Inflammation, Obesity | Altered Intercellular Communication | Understanding the extent to which visceral and subcutaneous body fat are associated with markers of nutrition and inflammation in patients on dialysis therapy could shed light on the obesity paradox and the biology of subcutaneous fat. | 28870376 |
| Inflammation | Altered Intercellular Communication | Subcutaneous fat may be an indicator of nutritional status, and visceral fat, an indicator of inflammation. | 28870376 |
| Peripheral Nervous System Diseases | Altered Intercellular Communication | To identify potential master switches in the neuro-immune balance, we aimed at characterizing inflammation-regulating miRNA profiles in patients with peripheral neuropathies. | 28870579 |
| Inflammation | Altered Intercellular Communication | The pleiotropic cytokine interleukin (IL)-10 is best characterized by its ability to downregulate inflammation and promote peripheral tolerance. | 28870600 |
| Inflammation, Diffuse Large B-Cell Lymphoma | Altered Intercellular Communication | Together, these results suggested that IL-10 could enhance CD8+ T cell inflammation in DLBCL patients. | 28870600 |
| Inflammation | Altered Intercellular Communication | KS lesions are driven by pathological angiogenesis, chronic inflammation, and oncogenesis, and various in vitro cell culture models have been developed to study these processes. | 28872106 |
| Inflammation, Structure of parenchyma of lung, Fatigue | Altered Intercellular Communication | This model demonstrated the following: 1) decreased forced expiratory volume 25, 50, and 75/forced vital capacity (FEV25/FVC, FEV50/FVC, and FEV75/FVC), indicating the deterioration of lung function; 2) enlarged lung alveoli, with lung parenchymal destruction; 3) reduced fatigue time and distance; and 4) increased inflammation. | 28872147 |
| Atherosclerosis, Inflammatory disorder, Cerebrovascular accident | Altered Intercellular Communication | BACKGROUND CCL11 is an important inflammatory cytokine associated with inflammation-related diseases such as atherosclerosis and stroke. | 28873081 |
| Sleep-Disordered Breathing, Impaired cognition, physiopathological, Hyperexcitability Behavior | Altered Intercellular Communication | These findings are interpreted in terms of a pathophysiological model of SDB in which hypoxia-mediated inhibitory neurotransmission deficit in DLPFC could lead to hyperexcitability and, potentially neuronal dysfunction and cognitive decline. | 28874569 |
| Inflammatory disorder | Altered Intercellular Communication | Evidence for a link between platelets indices and inflammation disease comes from recent studies. | 28874620 |
| Parkinson Disease, Restless Legs Syndrome | Altered Intercellular Communication | Restless legs syndrome in Parkinson disease: Clinical characteristics, abnormal iron metabolism and altered neurotransmitters. | 28874701 |
| Parkinson Disease, palladium, Restless Legs Syndrome | Altered Intercellular Communication | Relationships among clinical characteristics, iron metabolism and neurotransmitters in Parkinson disease (PD) patients with restless legs syndrome (RLS) remains unclear. | 28874701 |
| Glioblastoma Multiforme Pathway | Altered Intercellular Communication | Gap-junctional intercellular communication (GJIC) plays a major role in the malignant growth of glioma. | 28875331 |
| Inflammation | Altered Intercellular Communication | In addition, this report describes how to discriminate inflammation between SS and periprosthetic joint infection. | 28875344 |
| Inflammation | Altered Intercellular Communication | Subclinical inflammation that persists during attack-free periods can result in oxidative stress (OS) damage. | 28875601 |
| Inflammation | Altered Intercellular Communication | PFD may reduce the inflammation in AE-IP patients undergoing corticosteroid treatment. | 28876508 |
| Inflammation, Fibrosis Assessment, Granuloma | Altered Intercellular Communication | A semiquantatitive grading system was used to assess extent of fibroblastic foci, intra-alveolar fibroelastosis, visceral pleural fibrosis, chronic inflammation in areas of fibrosis, vascular fibrointimal thickening, and presence of granulomas. | 28877057 |
| Inflammation, Fibrosis Assessment, Granuloma | Altered Intercellular Communication | All biopsies showed intra-alveolar fibroelastosis, fibroblastic foci at the leading edge of fibrosis and chronic inflammation within areas of fibrosis, 91% showed vascular fibrointimal thickening of vessels, 73% showed pleural fibrosis, and 35% showed granulomas. | 28877057 |
| NCI CTEP SDC Myelodysplastic Syndrome Sub-Category Terminology, Respiratory Insufficiency | Altered Intercellular Communication | Myelodysplastic syndrome patients present more severe respiratory muscle impairment and reduced forced vital capacity: Is disordered inflammatory signaling the culprit? | 28877261 |
| Pain Distress Question, Inflammation | Altered Intercellular Communication | Physical examination showed a small expansion and redness of the right mandibular buccal and lingual cortical plates, but no signs of pain or inflammation were observed. | 28877285 |
| Inflammation | Altered Intercellular Communication | There is accumulating evidence that diet may be associated with markers of inflammation. | 28877589 |
| Inflammation | Altered Intercellular Communication | We have evaluated if an empirically developed questionnaire-based Anti-Inflammatory Diet Index (AIDI) may predict low-grade systemic chronic inflammation in a Nordic population. | 28877589 |
| Inflammation | Altered Intercellular Communication | Our results lead to the hypothesis that the empirically developed questionnaire-based dietary anti-inflammatory index may predict low-grade systemic inflammation. | 28877589 |
| Inflammation, Respiratory Hypersensitivity, mucus secretion | Altered Intercellular Communication | Knockin mice analogous to the human R213G SNP had lower airway hyperresponsiveness, inflammation, and mucus hypersecretion with decreased interleukin-33 (IL-33) in bronchoalveolar lavage fluid and reduced type II innate lymphoid cells (ILC2s) in lungs. | 28878123 |
| Inflammation, Ulcer | Altered Intercellular Communication | In this study, we assess the expression levels of OPN in chronic wounds to assess its potential contribution to the exacerbated inflammation seen in chronic ulcers, which is thought to contribute to poor healing. | 28880752 |
| Inflammation | Altered Intercellular Communication | This study provides strong histopathologic evidence that OPN expression is significantly increased in chronic wounds, suggesting that its upregulation could contribute to the exacerbated inflammation. | 28880752 |
| Inflammation, Virus Diseases | Altered Intercellular Communication | This is the first report of a human pathogenic ELANE mutation associated with a defect in NETosis and a distinct syndrome of recurrent viral infection and chronic inflammation. | 28881492 |
| Inflammation, Plasmacytosis | Altered Intercellular Communication | These observations highlight the need for IgG4 immunohistochemical staining of esophageal biopsies especially in patients with mucosal ulceration, chronic inflammation, and plasmacytosis on biopsy. | 28881885 |
| septic | Altered Intercellular Communication | C-reactive protein to albumin (CRP/Alb) ratio, a novel inflammation-based prognostic score, was first developed as a prognostic score for septic patients. | 28881893 |
| Acute Kidney Injury, CTCAE, Inflammation, Kidney Failure, Acute | Altered Intercellular Communication | Inflammation plays an important role in the initiation and progression of acute kidney injury (AKI). | 28882170 |
| Carcinogenic Chlorinated Hydrocarbon, Inflammation | Altered Intercellular Communication | We asked whether the presence of DM affects endothelial-derived (EMPs) and platelet-derived microparticles (PMPs) levels; and whether MPs levels associate with biomarkers of inflammation and oxidative stress in patients with CHC. | 28882977 |
| Carcinogenic Chlorinated Hydrocarbon, Inflammation, Diabetes Mellitus | Altered Intercellular Communication | We report a hitherto undescribed relationship between diabetes prevalence and apoptotic MPs-associated inflammation in patients with CHC. | 28882977 |
| Inflammation, Resolvin | Altered Intercellular Communication | Resolvins are omega-3 fatty acid derived potent bioactive lipids that resolve inflammation and modulate transient receptor potential channels. | 28883634 |
| Inflammation | Altered Intercellular Communication | These data highlight inflammation as a potentially important biological mechanism linking actor reports of life satisfaction to lower cardiovascular mortality. | 28884245 |
| Inflammation, Stomach Carcinoma, Cytomegalovirus Infections | Altered Intercellular Communication | We suggest the possibility that the addition of chronic inflammation of CMV infection to H. pylori-induced gastritis facilitated the development of gastric cancer. | 28884453 |
| Inflammation, Venous Injury, CTCAE | Altered Intercellular Communication | Using multivariate regression analysis, periarterial inflammation had significant association with major venous injury (P < 0.001). | 28887236 |
| Inflammation, Failure (biologic function) | Altered Intercellular Communication | The mechanisms underpinning the failure of inflammation to resolve in diseased musculoskeletal soft tissues are unknown. | 28887458 |
| Inflammation, SCAPULOPERONEAL MYOPATHY, X-LINKED DOMINANT | Altered Intercellular Communication | Taken together these results suggest that chronic inflammation in musculoskeletal soft tissues may result from dysregulated LM-SPM production, and that inhibition of 15-PGDH activity together with promoting resolution using SPM represents a novel therapeutic strategy to resolve chronic tendon inflammation. | 28887458 |
| Inflammation, Fibrosis Assessment | Altered Intercellular Communication | Treatment of chronic HCV with modern DAA therapy was associated with a significant improvement in LSM by VCTE measurement, suggesting possible early improvement in liver fibrosis along with resolution of inflammation over the first year after treatment completion. | 28887750 |
| Inflammation, Thrombosis, Pulmonary Embolism, Venous Thromboembolism, Influenza-like symptoms, Deep thrombophlebitis, vinyltriethoxysilane | Altered Intercellular Communication | Influenza-like illness and inflammation are known risk factors for venous thromboembolism (VTE), which includes deep vein thrombosis (DVT) and pulmonary embolism (PE). | 28888342 |
| Inflammation, Neoplasms | Altered Intercellular Communication | Inflammation plays a crucial role in tumor progression. | 28888400 |
| Blepharitis | Altered Intercellular Communication | Eyelid inflammation: An uncommon cause in occidental countries. | 28888529 |
| Inflammation, Hydropneumothorax, Fever, CTCAE | Altered Intercellular Communication | We present the atypical case of a 76-year-old man presenting with a hydro-pneumothorax, low-grade fever and elevated inflammation markers, after two complex percutaneous coronary interventions, executed 30 and 75 days prior. | 28888531 |
| Cartilage destruction, bone destruction, Pentalogy of Cantrell, Synovitis | Altered Intercellular Communication | In order to test the validity of the selected surgical technique as a way to manage persistent synovitis of the knee joint, as well as to slow down the cartilage and bone destruction, we studied the dynamics of biomarkers of inflammatory conditions, and bone and cartilage destruction after total arthroscopic synovectomy (TAS) of the knee joint. | 28889180 |
| Hepatic inflammation | Altered Intercellular Communication | Hepatic inflammation caused by dysregulated bile acid synthesis is reversible by butyrate supplementation. | 28892150 |
| Granulomatous inflammation, Granulomatous | Altered Intercellular Communication | Various patterns of granulomatous inflammation were observed including sarcoidal (31%), diffuse (25%), suppurative and granulomatous (25%), palisaded (13%) and lichenoid (6%). | 28892183 |
| Granulomatous inflammation, Leishmaniasis, Cutaneous | Altered Intercellular Communication | Multiple patterns of granulomatous inflammation occur in cutaneous leishmaniasis. | 28892183 |
| Inflammation | Altered Intercellular Communication | One subject withdrew voluntarily and one developed inflammation necessitating removal of the system. | 28892221 |
| Hyperandrogenemia, Inflammation, Hyperlipidemia, Cardiovascular Diseases, Atherosclerosis | Altered Intercellular Communication | Chronic inflammation, insulin resistance, hyperandrogenemia, hyperlipidemia and increased oxidative stress are known to have a role in the formation of atherosclerosis and cardiovascular disease. | 28892255 |
| vascular inflammations, Hypersensitivity | Altered Intercellular Communication | Localized vascular inflammation has been associated with endovascular nBCA use in histopathologic studies, but reports of systemic hypersensitivity reactions following endovascular embolization with nBCA are rare. | 28893128 |
| Airway structure, Exacerbation | Altered Intercellular Communication | This finding suggests that eosinophilic airway inflammation contributes to COPD exacerbations. | 28893134 |
| Inflammation, HIV Infections | Altered Intercellular Communication | We hypothesized that the chronic and persistent inflammation and immune activation associated with HIV disease leads to accelerated aging, characterized by CVD. | 28893184 |
| Degenerative polyarthritis | Altered Intercellular Communication | Hip Inflammation MRI Scoring System (HIMRISS) to predict response to hyaluronic acid injection in hip osteoarthritis. | 28893678 |
| Carcinoma of lung, Inflammation, Primary malignant neoplasm, Pulmonary Emphysema | Altered Intercellular Communication | Lipidomes of lung cancer and tumour-free lung tissues reveal distinct molecular signatures for cancer differentiation, age, inflammation, and pulmonary emphysema. | 28894173 |
| Inflammation, Pulmonary Emphysema | Altered Intercellular Communication | Partial least squares regression showed correlations between lipid profiles of tumour-free alveolar tissues and the degree of emphysema, inflammation status, and the age of patients. | 28894173 |
| Inflammation, Calcinosis | Altered Intercellular Communication | Inflammation, calcification, and structural integrity were also assessed. | 28895294 |
| Inflammation, Blood Clot | Altered Intercellular Communication | Inflammation and thrombus in the valve frame was minimal, but neointimal growth increased overtime. | 28895294 |
| Bacterial Endocarditis | Altered Intercellular Communication | Inflammation of the leaflets was mild, while structural changes were minimal, and one case had infective endocarditis. | 28895294 |
| Inflammation, Dyslipidemias, Diabetes Mellitus, Non-Insulin-Dependent | Altered Intercellular Communication | Relationship between Oxidative Stress, Inflammation and Dyslipidemia with Fatty Liver Index in Patients with Type 2 Diabetes Mellitus. | 28895641 |
| Inflammation, square decimeter, Dyslipidemias, Non-alcoholic Fatty Liver Disease, Diabetes Mellitus, Non-Insulin-Dependent | Altered Intercellular Communication | Considering the high prevalence of non-alcoholic fatty liver disease (NAFLD) in individuals with type 2 diabetes mellitus (DM2), we aimed to investigate the potential benefit of determining markers of oxidative stress, inflammation and dyslipidemia for prediction of NAFLD, as estimated with fatty liver index (FLI) in individuals with DM2. | 28895641 |
| Inflammation, Dyslipidemias, Diabetes Mellitus, Fatty Liver Disease | Altered Intercellular Communication | Multimarker approach, including biomarkers of oxidative stress, dyslipidemia and inflammation, could be of benefit in identifying patients with diabetes being at high risk of fatty liver disease. | 28895641 |
| Trachoma | Altered Intercellular Communication | On Tarawa, the most populous Kiribati island, both the active trachoma sign "trachomatous inflammation-follicular" (TF) and TT are present at prevalences warranting intervention. | 28898240 |
| Alzheimers Disease", Tauopathies, Inflammation | Altered Intercellular Communication | (doi:10.1093/awx174) for a scientific commentary on this article.Sleep deprivation increases amyloid-b, suggesting that chronically disrupted sleep may promote amyloid plaques and other downstream Alzheimer's disease pathologies including tauopathy or inflammation. | 28899014 |
| Stomach Carcinoma | Altered Intercellular Communication | Prognostic value of systemic immune-inflammation index in patients with gastric cancer. | 28899420 |
| Primary malignant neoplasm | Altered Intercellular Communication | Inflammation-based indexes have been used to predict survival and recurrence in cancer patients. | 28899420 |
| Malignant Neoplasms | Altered Intercellular Communication | Systemic immune-inflammation index (SII) was reported to be associated with prognosis in some malignant tumors. | 28899420 |
| Solitary fibrous tumor, Meningitis | Altered Intercellular Communication | Although meningeal inflammation was infrequent in patients with SFTSAE, SFTS virus was frequently detected in CSF with elevated MCP-1 and IL-8. | 28899841 |
| Peritonsillar, Inflammation, Tonsillitis | Altered Intercellular Communication | We analysed the presence of peritonsillar minor salivary glands and inflammation patterns in 114 adult tonsils representing three patient groups: recurrent AT, chronic tonsillitis (CT), and PTA. | 28900734 |
| Peritonsillar, Inflammation | Altered Intercellular Communication | The majority of our 114 tonsillectomy specimens, collected from patients with AT, CT, or PTA, presented with infected minor salivary glands, and inflammation of the peritonsillar space glands was evident. | 28900734 |
| Inflammation, Hypoxia | Altered Intercellular Communication | However, the association between chronic inflammation and high blood pressure caused by hypoxia remains to be fully elucidated. | 28901415 |
| Inflammatory Bowel Diseases, Disturbance, Inflammation | Altered Intercellular Communication | Bidirectional Regulation of Circadian Disturbance and Inflammation in Inflammatory Bowel Disease. | 28902123 |
| Inflammatory Bowel Diseases, Disturbance, Inflammation | Altered Intercellular Communication | We hypothesized that circadian timekeeping was perturbed in inflammatory bowel disease (IBD), and that the bidirectional regulation of circadian disturbance and inflammation may be involved in the pathogenesis of IBD. | 28902123 |
| Inflammatory Bowel Diseases, Inflammation | Altered Intercellular Communication | Our results suggested that inflammation and circadian genes showed complex bidirectional regulations that were relevant to IBD. | 28902123 |
| Inflammation, Peri-Implantitis | Altered Intercellular Communication | Resective peri-implantitis surgery seemed to reduce the amount of peri-implant inflammation. | 28902415 |
| Inflammation, Hypersensitivity | Altered Intercellular Communication | Increased activity at the left deltoid region suggests a false-positive finding related to radiotracer sequestration due to inflammation from a localized postvaccination hypersensitivity reaction. | 28902736 |
| Inflammation, Depression, CTCAE | Altered Intercellular Communication | Moreover, diet may influence inflammation as well as depression but no previous study examined whether inflammatory dietary patterns are related to depression in an older population. | 28903062 |
| Prostate carcinoma | Altered Intercellular Communication | Inflammation polymorphisms and prostate cancer risk in Jamaican men: Role of obesity/body size. | 28903065 |
| Inflammation, VITILIGO-ASSOCIATED MULTIPLE AUTOIMMUNE DISEASE SUSCEPTIBILITY 1 (finding), Pruritus | Altered Intercellular Communication | The multivariate analysis of factors associated with a high BMI (>=30) in vitiligo patients showed a significant association between a high BMI and a sudden onset of vitiligo (p = 0.021; OR = 3.83; 95% CI 1.22-11.99) and the presence of inflammation and pruritus (p = 0.031; OR = 3.26; 95% CI 1.11-9.57). | 28903118 |
| Inflammation, Specimen Type - Fistula | Altered Intercellular Communication | Because contact between the mesh and the cecum resulted in inflammation, a fistula formed in his bladder. | 28903762 |
| Inflammation, White matter lesions, Liver Dysfunction | Altered Intercellular Communication | The workup revealed brain white matter lesions, abnormal liver function tests and biological inflammation without evidence of Loa loa microfilariae in blood and cerebrospinal fluid. | 28904727 |
| Inflammation, Metabolic Syndrome X, Diabetes Mellitus, Renal Insufficiency, Chronic Kidney Diseases | Altered Intercellular Communication | Increased age, elevated fibrinogen, decreased albumin, diabetes mellitus, hyperTG, and worse virological control were risk factors for renal impairment.The HIV-positive patients in our area have a CKD prevalence of 4% to 5% (90% stage 3 CKD) associated with ageing, inflammation, worse immune control of HIV, TDF treatment, and metabolic syndrome. | 28906351 |
| Dental Plaque, Peri-Implantitis | Altered Intercellular Communication | While peri-implantitis represents a plaque-induced inflammatory condition, certain local factors might be associated with this biologic complication, as they imply plaque retention. | 28906504 |
| Inflammation, Metabolic Syndrome X, ETV3 wt Allele, Adenoma of large intestine | Altered Intercellular Communication | Metabolic syndrome (MetS) is an important cardiovascular risk factor for insulin resistance and has been linked to colorectal adenoma via inflammation. | 28910195 |
| Trachoma | Altered Intercellular Communication | Surveys are needed to guide trachoma control efforts in Mozambique, with WHO guidelines for intervention based on the prevalence of trachomatous inflammation-follicular (TF) in children aged 1-9 years and the prevalence of trichiasis in adults aged 15 years and above. | 28910562 |
| ARCN1 gene, Inflammation, Pulmonary Emphysema | Altered Intercellular Communication | These findings suggest a complex interaction between fat, inflammation, and emphysema that should be considered when phenotyping patients with COPD and provide new evidence of an inverse association between emphysema progression and chest subcutaneous fat. | 28910816 |
| Inflammation | Altered Intercellular Communication | The correlation between IL-6 and PAPP-A indicates that inflammation plays a role in promoting local tissue IGF activity. | 28911149 |
| Diabetes Mellitus, Non-Insulin-Dependent, Inflammation, Cyclophosphamide/Vincristine/Dacarbazine Regimen, Cardiovascular Diseases | Altered Intercellular Communication | Low-grade inflammation is involved in the development of type 2 diabetes and cardiovascular disease (CVD); however, prospective studies evaluating inflammatory markers as predictors of changes in insulin secretion and insulin sensitivity are lacking. | 28911155 |
| Inflammation | Altered Intercellular Communication | Thus, IL-37 may serve as a novel therapeutic target for the treatment of OA inflammation. | 28912428 |
| Mesenteric Lymphadenitis | Altered Intercellular Communication | What is Known: * Mesenteric adenitis is a self-limiting inflammatory condition with well-characterized clinical presentation and imaging features. | 28913615 |
| Inflammation, Obstruction, Adenocarcinoma of lung (disorder) | Altered Intercellular Communication | Here we report a patient with lung adenocarcinoma who was treated with nivolumab and developed obstruction because of biliary inflammation. | 28913619 |
| Inflammation | Altered Intercellular Communication | It is possible that regulatory cells in the immune system could function to suppress inflammation and possibly slow or reverse disease progression. | 28913840 |
| Inflammation, Acute postoperative pain | Altered Intercellular Communication | Preoperative ultraviolet B inflammation in skin: Modelling individual differences in acute postoperative pain and neuro-immune interactions. | 28913854 |
| Inflammation, Hyperalgesia | Altered Intercellular Communication | We conducted psychophysical and transcriptional analysis of hyperalgesia arising as a result of UVB-induced inflammation in patients before total knee arthroplasty (TKA, n = 23). | 28913854 |
| Inflammation, Pain, Postoperative | Altered Intercellular Communication | A simple model of UVB inflammation in the skin might predict the degree of a patient's neuro-immune response and the extent of their postoperative pain after total knee arthroplasty. | 28913854 |
| Refractory anemias, Inflammation, Primary malignant neoplasm, vinyltriethoxysilane | Altered Intercellular Communication | Thus, VTE may not only be a result of inflammation and immunological dysfunctions associated with RA, but may also be a marker for occult cancer. | 28913891 |
| Inflammation, Fibrosis Assessment, Lacrimal Duct Obstruction | Altered Intercellular Communication | Lacrimal sac mucosa and lumen were grossly inspected, and the frequency of lacrimal sac changes, such as significant inflammation or fibrosis, was analyzed in cases of CCO or canalicular obstruction. | 28913995 |
| Inflammation, Fibrosis Assessment | Altered Intercellular Communication | Of 253 cases with CCO, 122 (48.2%) showed clear lacrimal sac lumen, and the other 131 (51.8%) showed significant inflammation or fibrosis of the lacrimal sac. | 28913995 |
| Inflammation, Dental caries | Altered Intercellular Communication | Pulpotomy technique is most widely accepted clinical procedure for treating primary teeth with coronal pulp inflammation caused by caries with no involvement of the radicular pulp. | 28914245 |
| Inflammation, Atherosclerosis, Lupus Erythematosus, Systemic, Lupus Erythematosus | Altered Intercellular Communication | We evaluated the association of serum CysC with renal function, CV risk factors, inflammation, and subclinical atherosclerosis in Systemic Lupus Erythematosus (SLE) patients. | 28914371 |
| Inflammation | Altered Intercellular Communication | New evidence clarifying the correlation between ROS and inflammation has indicated that oxidative stress can up-regulate inflammatory cytokines. | 28914997 |
| Gingivitis, Inflammation, Periodontitis | Altered Intercellular Communication | Gingivitis, an inflammation of the gingival tissues, typically progresses to periodontitis. | 28915302 |
| Arthralgia, Inflammation, Arthritis | Altered Intercellular Communication | Absence of ultrasound inflammation in patients presenting with arthralgia rules out the development of arthritis. | 28915847 |
| MTA2 gene, Communicable Diseases, Ectopic Pregnancy, Pelvic Inflammatory Disease | Altered Intercellular Communication | C. trachomatis infection was associated with age, marital status, pregnancy, and hormonal contraceptive use (all p = 0.01); intrauterine device use and previous premature birth (both p = 0.03); and infection during pregnancy, previous ectopic pregnancy, pelvic inflammatory disease (PID), and green vaginal discharge (all p = 0.04). | 28915869 |
| Inflammation, Colorectal Carcinoma, Neoplasms | Altered Intercellular Communication | Given the importance of inflammation in CRC, we tested whether polymorphic variants in this gene could affect the risk of developing this neoplasia hypothesizing a role of TAS2R16 in modulating chronic inflammation within the gut. | 28915899 |
| Inflammation, Diabetes Mellitus | Altered Intercellular Communication | Ischaemia-reperfusion injury (IRI) causes inflammation, and diabetes is known to exacerbate this inflammatory response in the kidney, whereas alarmin IL-33 could act as an innate immune mediator during kidney IRI. | 28916390 |
| vascular inflammations | Altered Intercellular Communication | Small RNA-seq during acute maximal exercise reveal RNAs involved in vascular inflammation and cardiometabolic health: brief report. | 28916639 |
| Sepsis, vascular inflammations, Obesity, Cardiovascular Diseases | Altered Intercellular Communication | Previous work revealed a strong role for miR-181b-5p in vascular inflammation in obesity, insulin resistance, sepsis, and cardiovascular disease. | 28916639 |
| Inflammation, diabetic, Choline Dehydrogenase, Mitochondrial | Altered Intercellular Communication | Gene expression related to insulin, lipid and inflammation were quantified in peripheral blood mononuclear cells (PBMC) of diabetic patients with CHD with RT-PCR method. | 28916975 |
| Inflammation, Chronic Fatigue Syndrome, Depression, CTCAE | Altered Intercellular Communication | Depression, evening salivary cortisol and inflammation in chronic fatigue syndrome: A psychoneuroendocrinological structural regression model. | 28918107 |
| Inflammation, Chronic Fatigue Syndrome, Depression, CTCAE, physiopathological, Chronic disease | Altered Intercellular Communication | Since depression is known to be associated with HPA axis dysfunction and greater inflammation, a psychoneuroendocrinological (PNE) model of inflammation was examined in persons diagnosed with CFS in order to uncover underlying biopsychosocial mechanisms in this poorly understood chronic illness. | 28918107 |
| Inflammation, Tumor necrosis, Depression, CTCAE, Bipolar Disorder | Altered Intercellular Communication | Depression was directly related to evening salivary cortisol and inflammation, such that higher evening cortisol predicted greater depressive symptoms (b=0.215, p<0.01) and higher pro-inflammatory cytokines (interleukin-2 [IL-2], IL-6, and tumor necrosis factor-alpha [TNF-a] levels (b=0.185, p<0.05), when controlling for covariates. | 28918107 |
| Inflammation, Depression, CTCAE | Altered Intercellular Communication | Results highlight the role of depression, cortisol and inflammation in possible biological mechanisms involved in the pathophysiology of CFS. | 28918107 |
| Inflammation, HIV Antigens | Altered Intercellular Communication | Systemic inflammation is a prognostic factor requiring validation in HIV-associated HCC. | 28918424 |
| Inflammation, Malignant Neoplasms, HIV Infections | Altered Intercellular Communication | Systemic inflammation, as measured by NLR, is a prognostic determinant associated with adverse pathological features of malignancy, but not coexisting HIV infection, suggesting a tumour-promoting role of the innate immune response that warrants further investigation in mechanistic studies. | 28918424 |
| Inflammation, Atherosclerosis | Altered Intercellular Communication | Inflammation has been reported to be involved in the pathogenesis of atherosclerosis. | 28918492 |
| Inflammation, Diabetes Mellitus, Non-Insulin-Dependent, Metabolic Syndrome X, Cardiovascular Diseases | Altered Intercellular Communication | This principal objective of this study was to investigate if the secretion of neuregulin 4 (Nrg4), a soluble protein associated with metabolic syndrome and subclinical cardiovascular disease, is correlated with the inflammation marker high-sensitivity C-reactive protein (hs-CRP) in patients with newly diagnosed type 2 diabetes mellitus (nT2DM). | 28918492 |
| Liver carcinoma, Hepatitis, Neoplasms, FAM126A gene | Altered Intercellular Communication | Development of hepatocellular carcinoma (HCC) is associated with alterations in the transforming growth factor-beta (TGF-b) signaling pathway, which regulates liver inflammation and can have tumor suppressor or promoter activities. | 28918914 |
| Inflammation, Fibrosis Assessment, Neoplasms | Altered Intercellular Communication | These correlated with changes in expression of genes in the pathways; up-regulation of genes in this pathway would contribute to inflammation and fibrosis, whereas down-regulation would indicate loss of TGF-b tumor suppressor activity. | 28918914 |
| Inflammation, Damage | Altered Intercellular Communication | Inflammation in MS NAWM was characterized, compared to non immune-mediated conditions, by higher VCAM-1 expression, higher density of perivascular lymphocytes, focal perivascular inflammation with microglial expression of M1 markers, ongoing acute axonal damage correlating with VCAM-1 expression but not with microglia activation. | 28919237 |
| Wallerian Degeneration, Inflammation, Damage | Altered Intercellular Communication | Inflammatory changes in MS NAWM share all the main features observed in the WM in non immune-mediated conditions with wallerian axonal degeneration (with differences to a large extent more quantitative than qualitative), but with superimposition of disease-specific perivascular inflammation and ongoing acute axonal damage. | 28919237 |
| Inflammation, Rheumatoid Arthritis | Altered Intercellular Communication | MMP-8 and TIMP-1 are associated to periodontal inflammation in patients with rheumatoid arthritis under methotrexate immunosuppression - First results of a cross-sectional study. | 28919284 |
| Inflammation, SMYD1 gene | Altered Intercellular Communication | Furthermore, higher blood concentrations of MMP-8 and tissue inhibitor of MMP (TIMP-1) were detected in patients with increased periodontal inflammation (BOP positive, p < 0.01). | 28919284 |
| Inflammation, "Crohns disease of the ileum | Altered Intercellular Communication | Computed tomography revealed segmental small bowel wall thickening with chronic inflammation suggestive of Crohn's ileitis and oral steroids were commenced; only later, ingestion of a foreign body was suspected. | 28920530 |
| Inflammation, Chronic disease | Altered Intercellular Communication | Evidence from the literature suggests that dietary flaxseed lignans have the ability to modulate inflammation, which is recognized as the underlying basis of multiple chronic human diseases in older adults. | 28922068 |
| Inflammation, Arteriopathic disease | Altered Intercellular Communication | The association between cigarette smoking and inflammation: The Genetic Epidemiology Network of Arteriopathy (GENOA) study. | 28922371 |
| Inflammation, Hypertension, CTCAE, Cardiovascular system | Altered Intercellular Communication | To inform the study and regulation of emerging tobacco products, we sought to identify sensitive biomarkers of tobacco-induced subclinical cardiovascular damage by testing the cross-sectional associations of smoking with 17 biomarkers of inflammation in 2,702 GENOA study participants belonging to sibships ascertained on the basis of hypertension. | 28922371 |
| Experimental Organism Luteinized Unruptured Follicle, Inflammation, Rupture, Aneurysm, Ruptured, Aneurysm | Altered Intercellular Communication | In conclusion, detection of thickened IEL, leaky vasa vasorum, and heavy inflammation as seen in ruptured IA in comparison to unruptured IA may identify aneurysms at risk of rupture, and management strategies preventing development of vasa vasorum or inflammation may reduce the risk of aneurysmal rupture. | 28922850 |
| Inflammation, Arteriopathic disease, Diabetes Mellitus | Altered Intercellular Communication | The mixture of shared with disparate determinants for arterial disease in the heart and the legs implies nonidentical pathogenesis: cholesterol dominant in the former, and inflammation (high-sensitivity C-reactive protein, diabetes mellitus, smoking) in the latter. | 28923990 |
| Seizures, Creutzfeldt-Jakob disease | Altered Intercellular Communication | Inhibition of IL-1b Signaling Normalizes NMDA-Dependent Neurotransmission and Reduces Seizure Susceptibility in a Mouse Model of Creutzfeldt-Jakob Disease. | 28924012 |
| Stable chronic Graft vs Host Disease, Inflammation, Fibrosis Assessment | Altered Intercellular Communication | Plasma levels of soluble factors associated with inflammation, fibrosis, and cGVHD significantly decreased over time with ibrutinib. | 28924018 |
| Inflammation, Fatty degeneration | Altered Intercellular Communication | Her liver sample showed marked improvement, especially in steatosis, inflammation, and ballooning. | 28924123 |
| Inflammation, Migraine Disorders | Altered Intercellular Communication | Based on this case, the pathophysiology of RPON may involve temporary nerve inflammation with migraine. | 28924127 |
| Vitreous inflammatory cells, Uveitis, Posterior, Uveitis | Altered Intercellular Communication | We report a new clinical sign of vitreous inflammation in patients with posterior uveitis: spectral-domain optical coherence tomography identified stalagmite-like, discrete, diffusely distributed, hyperreflective, preretinal deposits in previously vitrectomized eyes of 2 patients during flares of posterior uveitis. | 28924415 |
| Cardiac Hypertrophy, Chronic Kidney Diseases, Congestive heart failure | Altered Intercellular Communication | Elevated levels of fibroblast growth factor 23 (FGF23), a bone-derived phosphaturic hormone, are associated with a number of pathologic conditions including chronic kidney disease, cardiac hypertrophy, and congestive heart failure. | 28924605 |
| Inflammation, Malnutrition | Altered Intercellular Communication | IL-6 and sICAM-1 were independent preoperative prognostic factors in EHC patients, causing continuous inflammation and malnutrition in collaboration with other pro-angiogenic factors. | 28925763 |
| Atrial Fibrillation by ECG Finding | Altered Intercellular Communication | Atrial Fibrillation Ablation Increases Inflammation-Chemokine Modulation Suppresses Activation of Leukocytes Isolated after Ablation. | 28925907 |
| Atrial Fibrillation, Inflammation, Atrial Fibrillation by ECG Finding | Altered Intercellular Communication | Atrial fibrillation (AF) ablation is associated with increased circulating markers of inflammation. | 28925907 |
| Inflammation, Cardiac Arrhythmia | Altered Intercellular Communication | Innate immune or inflammation pathways up-regulate mononuclear cell responses and may increase the risk for recurrent arrhythmia. | 28925907 |
| Communicable Diseases, Endophthalmitis, CTCAE, Inflammation | Altered Intercellular Communication | It is possible that some aspect of the infection, inflammation, or treatment of endophthalmitis had a disease-modifying impact on the eAMD. | 28925926 |
| Rheumatoid Arthritis, Inflammation, Atherosclerosis | Altered Intercellular Communication | Retinal vessel morphology in rheumatoid arthritis: Association with systemic inflammation, subclinical atherosclerosis, and cardiovascular risk. | 28926162 |
| Refractory anemias, Inflammation, Atherosclerosis | Altered Intercellular Communication | We examined retinal microvascular diameters in RA, particularly in regard to systemic inflammation, subclinical atherosclerosis, and cardiovascular risk. | 28926162 |
| Inflammation, Abnormality of the vasculature, Atherosclerosis | Altered Intercellular Communication | Inflammation appears as the biological link for the observed association between retinal microvascular abnormalities and subclinical atherosclerosis. | 28926162 |
| Hepatitis C, Neoplasms | Altered Intercellular Communication | On the other hand, the reduction of inflammation-triggered immune surveillance after very rapid elimination of the hepatitis C virus may have favored tumor progression. | 28927498 |
| Inflammation, Rheumatoid Arthritis | Altered Intercellular Communication | Astrocyte elevated gene-1 promotes inflammation and invasion of fibroblast-like synoviocytes in rheumatoid arthritis. | 28927747 |
| Refractory anemias, Inflammation | Altered Intercellular Communication | Collectively, Our findings provided evidence that AEG-1 contributed to the production of inflammatory cytokines, migration and invasion of RA FLS, and underscored the importance of AEG-1 in the inflammation process of RA. | 28927747 |
| Inflammation, Psoriasis, Cardiovascular Diseases | Altered Intercellular Communication | To understand the effects of psoriasis medications on systemic inflammation associated with cardiovascular risks, we studied blood proteins related to inflammation and cardiovascular disease archived from a phase 3 clinical trial of tofacitinib and etanercept in adults with moderate-to-severe psoriasis. | 28927890 |
| Liver carcinoma, Hepatitis, Chronic, Neoplasms, FAM126A gene | Altered Intercellular Communication | Purpose: Hepatocellular carcinoma (HCC) often arises in the setting of chronic liver inflammation and may be responsive to novel immunotherapies.Experimental Design: To characterize the immune microenvironment in HCC, IHC staining was performed for CD8-positive T lymphocytes, PD-1-positive, and LAG-3-positive lymphocytes, CD163-positive macrophages, and PD-L1 expression in tumor and liver background from 29 cases of resected HCC.Results: Expression of CD8 was reduced in tumor, and expression of CD163 was reduced at the tumor interface. | 28928158 |
| Inflammation, Atherosclerosis | Altered Intercellular Communication | Individual serum saturated fatty acids and markers of chronic subclinical inflammation: the Insulin Resistance Atherosclerosis Study. | 28928169 |
| Inflammation, Fever, CTCAE, Fever of Unknown Origin | Altered Intercellular Communication | The value of 18F-FDG-PET/CT in identifying the cause of fever of unknown origin (FUO) and inflammation of unknown origin (IUO): data from a prospective study. | 28928271 |
| Inflammation, Fever, CTCAE, Fever of Unknown Origin | Altered Intercellular Communication | Fever of unknown origin (FUO) and inflammation of unknown origin (IUO) are diagnostically challenging conditions. | 28928271 |
| Inflammation, Neuralgia | Altered Intercellular Communication | Animal experiment showed that LncRNA NONRATT021972 siRNA attenuated inflammation via decreasing TNF-a and alleviated neuropathic pain. | 28928602 |
| Inflammation, Mood Disorders | Altered Intercellular Communication | There has been increasing evidence that chronic low-grade inflammation is associated with mood disorders. | 28929992 |
| Inflammation, Mood Disorders | Altered Intercellular Communication | There was little evidence for inflammation markers at baseline predicting mood disorders at follow-up. | 28929992 |
| Minimal Disseminated Disease, Inflammation | Altered Intercellular Communication | The prospective unidirectional association between current MDD subtype with atypical features and hsCRP levels at follow-up suggests that inflammation may be a consequence of this condition. | 28929992 |
| Inflammation, Cardiovascular Diseases | Altered Intercellular Communication | The role of inflammation, particularly hsCRP that is critically involved in cardiovascular diseases, warrants further study. | 28929992 |
| Communicable Diseases, Inflammation, Herpesviridae Infections | Altered Intercellular Communication | Persistent herpesvirus infections including cytomegalovirus (CMV) infection may be particularly important for telomere dynamics via mechanisms such as inflammation, oxidative stress, and their impact on peripheral blood lymphocyte composition. | 28931225 |
| Malaria, Falciparum, Inflammation | Altered Intercellular Communication | Monocyte dysregulation and systemic inflammation during pediatric falciparum malaria. | 28931756 |
| Inflammation, Malaria | Altered Intercellular Communication | Inflammation and monocytes are thought to be important to human malaria pathogenesis. | 28931756 |
| Inflammation, Malaria, Acute malaria, Parasitemia | Altered Intercellular Communication | However, the relationship of inflammation and various monocyte functions to acute malaria, recovery from acute malaria, and asymptomatic parasitemia in endemic populations is poorly understood. | 28931756 |
| Inflammation | Altered Intercellular Communication | Periodontal-induced chronic inflammation triggers macrophage secretion of Ccl12 to inhibit fibroblast-mediated cardiac wound healing. | 28931761 |
| Inflammation | Altered Intercellular Communication | The goal of this study was to elucidate the molecular basis for impaired cardiac wound healing in the setting of periodontal-induced chronic inflammation. | 28931761 |
| Infarction, Inflammation | Altered Intercellular Communication | Causal network analysis of 168 inflammatory and extracellular matrix genes revealed that chronic inflammation induced by a subseptic dose of Porphyromonas gingivalis lipopolysaccharide (LPS) exacerbated infarct expression of the proinflammatory cytokine Ccl12. | 28931761 |
| Inflammation | Altered Intercellular Communication | Ccl12 prevented initiation of the reparative response by prolonging inflammation and inhibiting fibroblast conversion to myofibroblasts, resulting in diminished scar formation. | 28931761 |
| Inflammation, Psoriasis | Altered Intercellular Communication | Chitinase-3-Like Protein 1 (YKL-40) Is a New Biomarker of Inflammation in Psoriasis. | 28932021 |
| Inflammation | Altered Intercellular Communication | Chitinase-3-like protein 1 (YKL-40) plays a role in inflammation. | 28932021 |
| Inflammation, Psoriasis | Altered Intercellular Communication | The study was undertaken to check whether YKL-40 is a reliable biomarker of inflammation in psoriasis. | 28932021 |
| Inflammation, Psoriasis | Altered Intercellular Communication | YKL-40 could be considered as a useful biomarker of inflammation in psoriasis and is more sensitive than CRP or WBC. | 28932021 |
| Psoriatic Juvenile Idiopathic Arthritis, Inflammation | Altered Intercellular Communication | Increased YKL-40 may indicate psoriatic patients with a higher level of systemic inflammation, which may determine disease management. | 28932021 |
| Inflammation | Altered Intercellular Communication | Results showed an upregulation of key pro-inflammatory cytokine mRNA expression (TNF-a, IL-1b, IL-6) during inflammation with an associated downregulation of 11b-HSD2 mRNA expression when compared to controls. | 28932959 |
| Refractory anemias, Rheumatoid Arthritis, Inflammation, Autoimmune Disorder, CTCAE | Altered Intercellular Communication | Rheumatoid arthritis (RA) is an autoimmune disorder characterized by chronic inflammation of the joints. | 28933133 |
| Arthralgia, Inflammation, Refractory anemias | Altered Intercellular Communication | We aim to investigate treatment of the nervous system to relieve joint pain and inflammation in RA. | 28933133 |
| Refractory anemias, Inflammation | Altered Intercellular Communication | Nerve mobilization, a nervous system-specific therapeutic exercise, was applied on RA patients to determine the effect of nerve mobilization on joint inflammation. | 28933133 |
| Pain Distress Question, Inflammation | Altered Intercellular Communication | Several successful cases with the use of this device are presented in which pain relief, enhancement of epithelial migration, inflammation reduction, bacterial control, and wound size reduction were achieved. | 28933696 |
| Inflammation, Venous Thrombosis | Altered Intercellular Communication | Perivascular Perfusion on Contrast-Enhanced Ultrasound (CEUS) Is Associated with Inflammation in Patients with Acute Deep Vein Thrombosis. | 28933797 |
| Inflammatory disorder, allergic inflammation, CDISC SDTM Lesion Complexity Terminology, Disease | Altered Intercellular Communication | Although allergic inflammation is characterized by a T helper (Th) 2-dominant immune response, the discovery of a role for new T cell subsets in inflammatory diseases has added an additional layer of complexity to the understanding of the pathogeneses of allergic diseases. | 28934137 |
| Inflammation | Altered Intercellular Communication | Whether intestinal damage and inflammation underlie mortality is unknown. | 28934432 |
| Inflammation | Altered Intercellular Communication | HEU infants have higher inflammation than HIV-unexposed infants until at least 6 months, which may contribute to poor health outcomes. | 28934432 |
| Paranasal Sinus Disorder, Inflammation, vinyltriethoxysilane | Altered Intercellular Communication | Overall, those with VTE had a greater disease burden and older age, sinus disease, longer hospitalization and increased inflammation were VTE risk factors. | 28934665 |
| Inflammation, Psoriasis, Dermatitis | Altered Intercellular Communication | The clinical and histologic phenotype, as well as the transcriptome, of imiquimod-induced inflammation in human skin resembles acute contact dermatitis rather than psoriasis. | 28935206 |
| Intervertebral Disc Degeneration | Altered Intercellular Communication | TGF-b1 suppresses CCL3/4 expression through the ERK signaling pathway and inhibits intervertebral disc degeneration and inflammation-related pain in a rat model. | 28935976 |
| Pain Distress Question | Altered Intercellular Communication | The results of this study indicate that TGF-b1 may represent a therapeutic target for the control of inflammation-related pain associated with IVDD. | 28935976 |
| Inflammation | Altered Intercellular Communication | Innate lymphoid cells (ILCs) have emerging roles in setting the milieu for physiological, but also pathological, immune responses and inflammation. | 28936778 |
| Inflammation | Altered Intercellular Communication | Psoriatic lesions are characterized by hyperproliferation, aberrant differentiation of keratinocytes resistant to apoptosis and inflammation. | 28937251 |
| Inflammation | Altered Intercellular Communication | Selected miRNAs, such as miR-29a-3p, miR-146a-5p or miR-222-3p with an established role in extracellular matrix formation and inflammation were associated with spinal changes and/or disease activity assessed by BASDAI in AS patients, including miR-625-3p reflecting disease activity in AS with spinal involvement. | 28938006 |
| Inflammation | Altered Intercellular Communication | We hypothesize that differential systemic levels of miRNA expression reflect miRNA dysregulation at sites of spinal inflammation or bone formation where these molecules contribute to the development of pathophysiological features typical of AxSpA. | 28938006 |
| Tumor necrosis, Inflammation | Altered Intercellular Communication | Serum adiponectin and tumor necrosis factor-a (TNF-a), a biomarker of inflammation, were also measured. | 28938100 |
| Airway structure, Bronchial Hyperreactivity | Altered Intercellular Communication | Bronchial hyperreactivity, airway inflammation, and sensitization were significantly different among the 3 groups. | 28939411 |
| Inflammatory Bowel Diseases, Communicable Diseases, Inflammation | Altered Intercellular Communication | The innate immune system of host cells provides a first-line defence against pathogenic infection, whereas an uncontrolled inflammatory response under homeostatic conditions usually leads to pathological consequences, as exemplified by the chronic inflammation of IBD. | 28940253 |
| Inflammation | Altered Intercellular Communication | Our results suggest a mixed immunological response of remodeling and inflammation following the implantation. | 28940406 |
| Delirium, Inflammation, Postoperative delirium | Altered Intercellular Communication | This report shows an incidence of 28% of delirium, occurring after CRS-HIPEC and suggests a role for systemic inflammation in the development of postoperative delirium. | 28940461 |
| Inflammation, Neoplasms | Altered Intercellular Communication | However, clinical response assessment can be problematic due to immune-related inflammation at established tumor sites. | 28940544 |
| melanoma, Neoplasms, Granulomatous inflammation | Altered Intercellular Communication | Tumor biopsies are encouraged after 4 to 6 months of TVEC administration to differentiate melanoma from granulomatous inflammation. | 28940544 |
| Inflammatory disease of mucous membrane | Altered Intercellular Communication | The investigational group also demonstrated substantial improvement in both mucosal inflammation and Valsalva maneuver at 6-week follow-up compared to controls. | 28940574 |
| Myopathy, Intestinal Pseudo-Obstruction | Altered Intercellular Communication | Among patients with a neuropathic manometry pattern and abnormal histopathology, only 23% had an enteric neuropathy, whereas 62% had neuromuscular inflammation, and 15% an enteric myopathy. | 28941004 |
| Inflammation, Fluid overload | Altered Intercellular Communication | Volume overload in these patients is associated with inflammation. | 28941049 |
| Inflammation, Carcinogenesis | Altered Intercellular Communication | Chronic inflammation may play a role in prostate cancer carcinogenesis. | 28941222 |
| Demyelination | Altered Intercellular Communication | Dynamic Changes in Brain Mesenchymal Perivascular Cells Associate with Multiple Sclerosis Disease Duration, Active Inflammation, and Demyelination. | 28941240 |
| Inflammation, Demyelination, Disease | Altered Intercellular Communication | In conclusion, we demonstrate the presence of MPC subgroups in control human brain vasculature, and their phenotypic changes in MS brain, which correlated with inflammation, demyelination and MS disease duration. | 28941240 |
| Nonalcoholic Steatohepatitis, Inflammation, Liver carcinoma, Steatohepatitis, Fibrosis Assessment, FAM126A gene, Fatty Liver Disease | Altered Intercellular Communication | Non-alcoholic steatohepatitis (NASH) is characterized by hepatic steatosis, inflammation and eventually fibrosis, and may progress to hepatocellular carcinoma (HCC). | 28941732 |
| Inflammation, Fibrosis Assessment, Fatty degeneration, Fatty Liver Disease | Altered Intercellular Communication | SNTA mRNA expression was reduced in NASH liver and negatively correlated with steatosis, inflammation, fibrosis and NASH scores. | 28941732 |
| Inflammation, Fibrosis Assessment, Diabetes Mellitus, Non-Insulin-Dependent, Fatty Liver Disease | Altered Intercellular Communication | In the NASH patients, those with type 2 diabetes had a higher fibrosis score, reduced inflammation and increased hepatic SNTA mRNA levels demonstrating a strong association of SNTA mRNA levels with inflammation. | 28941732 |
| Bronchial Epithelial Dysplasia, Inflammation, Asthma | Altered Intercellular Communication | Elderly subjects had an increase in some markers of systemic inflammation and bronchial epithelial dysfunction compared with young people with asthma. | 28941741 |
| Airway structure, Inflammation, Airway Obstruction | Altered Intercellular Communication | Asthma in the elderly presents as a specific phenotype associated with increased airway obstruction and mixed airway inflammation in addition to signs of systemic inflammation. | 28941741 |
| Inflammation | Altered Intercellular Communication | Mortality prediction in stable hemodialysis patients is refined by YKL-40, a 40-kDa glycoprotein associated with inflammation. | 28941940 |
| HD Term Type, Inflammation | Altered Intercellular Communication | Chronic inflammation contributes to increased mortality in hemodialysis (HD) patients. | 28941940 |
| Inflammation | Altered Intercellular Communication | Compared with weak PCV, severe PCV exhibited prominent immune complex deposition, complement activation, and infiltration of inflammatory cells, suggesting inflammation plays a key role in PCV progression. | 28941979 |
| Inflammation, Epidermolysis | Altered Intercellular Communication | Calcitriol Treatment Ameliorates Inflammation and Blistering in Mouse Models of Epidermolysis Bullosa Acquisita. | 28942362 |
| Granulomatous inflammation, Infectious Mononucleosis | Altered Intercellular Communication | A subsequent histological examination revealed granulomatous inflammation characteristic of infectious mononucleosis. | 28942415 |
| Inflammation, Fibrosis Assessment | Altered Intercellular Communication | A biomarker of fibrosis, sST2, and a biomarker of inflammation, hs-CRP, predict the risk of occurrence of new-onset AF in patients with CAD. | 28942872 |
| Drug-Induced Liver Disease, Inflammation, Idiopathic Pulmonary Fibrosis | Altered Intercellular Communication | IL-38 may play an important role in acute and/or chronic inflammation in anticancer drug-induced lung injury and acute exacerbation of IPF. | 28942884 |
| Communicable Diseases, Inflammation | Altered Intercellular Communication | It is an evolutionary conserved multifunctional protein localized primarily in the mitochondrial matrix and has roles in inflammation and infection processes, mitochondrial ribosome biogenesis, and regulation of apoptosis and nuclear transcription. | 28942965 |
| Communicable Diseases, Inflammation | Altered Intercellular Communication | None of the patients showed signs of inflammation or infection based on clinical and laboratory examinations. | 28943450 |
| Inflammation | Altered Intercellular Communication | In addition, proteins associated with inflammation and the innate immune response-e.g., cluster of differentiation 14, annexin-2, and components of the complement system-were upregulated in PSC. | 28943450 |
| Inflammation, Cholangitis, Malignant Neoplasms | Altered Intercellular Communication | Thus, the bile-duct bile proteome of patients with PSC shows disease-specific changes associated with inflammation and the innate immune response even in the absence of obvious clinical signs of cholangitis, malignancy, or inflammation. | 28943450 |
| Chronic Obstructive Airway Disease, Pneumonitis, Diabetes Mellitus | Altered Intercellular Communication | The involvement of pulmonary inflammation in insulin resistance remains unclear, but smoking is known to be a risk factor for diabetes as well as chronic obstructive pulmonary disease. | 28943558 |
| Interstitial Fibrosis Assessment | Altered Intercellular Communication | Renal biopsy showed some sclerosed glomeruli, some with mesangial proliferation, and tubulointerstitial inflammation with eosinophils and plasma cells and mild interstitial fibrosis. | 28943633 |
| Inflammation, Asthma | Altered Intercellular Communication | T cell-associated inflammation, particularly type 2 inflammation, has an important role in asthma pathogenesis, which is suppressed by regulatory T cells (Tregs). | 28944837 |
| Symptoms, Asthma, Airway structure | Altered Intercellular Communication | Inhibition of PIM2 attenuated asthma symptoms, and improved AHR and airway inflammation compared with asthmatic mice without inhibition of PIM2. | 28944837 |
| Airway structure, Asthma, AHR wt Allele, Symptoms | Altered Intercellular Communication | In conclusion, PIM2 may exhibit an important role in asthma pathogenesis and exacerbate AHR, airway inflammation and asthma symptoms. | 28944837 |
| Inflammation | Altered Intercellular Communication | It plays critical roles in various tissues throughout development and is implicated in tumorigenesis and inflammation in adulthood. | 28945198 |
| Acromegaly, Sialorrhea | Altered Intercellular Communication | Acromegaly is characterized by growth hormone (GH) and insulinlike growth factor-1 (IGF-1) hypersecretion, and GH and IGF-1 play important roles in regulating body composition and glucose homeostasis. | 28945897 |
| Gastritis | Altered Intercellular Communication | There was a significant (p = 0.027) relationship between the IL-1b 511 C-carrier and histological gastric inflammation in H. pylori-infected gastritis patients. | 28946145 |
| Inflammation, Insulin Resistance | Altered Intercellular Communication | Both insulin-resistance and chronic low-grade inflammation are involved in this relationship. | 28946871 |
| Inflammation, Destruction of tissue | Altered Intercellular Communication | Usually, the foreign objects cause chronic inflammation and local tissue destruction, which give rise to symptoms. | 28946895 |
| Inflammation | Altered Intercellular Communication | Alveolar bone graft surgery was delayed because of local chronic inflammation due to the foreign object. | 28946895 |
| Inflammation | Altered Intercellular Communication | It can be concluded that a new factor -namely the dialysis technique- may be associated with falling testosterone levels and the associated loss of muscle mass and inflammation. | 28946965 |
| Inflammation, Rheumatoid Arthritis, Disease remission | Altered Intercellular Communication | Traditional markers of inflammation are often required for inclusion in rheumatoid arthritis trials, yet patients with active disease may have normal lab tests. | 28947312 |
| Inflammation | Altered Intercellular Communication | CE findings were normal in 17 patients (40%), mild inflammation in 19 (44%), and moderate to severe inflammation in 7 (16%). | 28947363 |
| Clinical Events Domain, Inflammatory disease of mucous membrane | Altered Intercellular Communication | Of the 26 patients (60%) with mucosal inflammation on CE, 85% had elevated baseline fecal calprotectin and 77% elevated lactoferrin level. | 28947363 |
| Inflammation | Altered Intercellular Communication | Calprotectin and lactoferrin were normal in all patients without inflammation and elevated in all with moderate to severe inflammation. | 28947363 |
| Clinical Events Domain, Inflammatory disease of mucous membrane | Altered Intercellular Communication | During follow-up, 14% of patients exhibited a clinical flare; all had mucosal inflammation at CE and 83% had elevated baseline calprotectin and lactoferrin levels. | 28947363 |
| Motor Neuron Disease, Inflammation, Dysbiosis | Altered Intercellular Communication | Gut inflammation and dysbiosis in human motor neuron disease. | 28947596 |
| Gastrointestinal inflammation | Altered Intercellular Communication | A majority of patients had signs of intestinal inflammation. | 28947596 |
| ARCN1 gene, Inflammation | Altered Intercellular Communication | Serum levels of Gal-3 in 44 patients with COPD were further analyzed and correlated with the parameters of lung function and the biomarkers of systemic inflammation. | 28947730 |
| ARCN1 gene, Inflammation | Altered Intercellular Communication | CONCLUSIONS Our results indicated that serum Gal-3 is increased in AECOPD patients, which is also positively associated with systemic inflammation and smoking in patients with COPD, suggesting that Gal-3 might be a valuable biomarker for AECOPD. | 28947730 |
| Inflammation | Altered Intercellular Communication | Cancer-related inflammation appears to have a greater impact on taste perception than an acute inflammatory process. | 28948404 |
| Crohns disease of large bowel", Ulcerative Colitis, Colitis | Altered Intercellular Communication | For the noninvasive monitoring of the activity of colonic inflammation, we validated a symptom index suitable for ulcerative colitis and colonic Crohn's disease. | 28948412 |
| Inflammatory Bowel Diseases, Inflammation | Altered Intercellular Communication | We also evaluated the correlation of the patient-reported influence of the IBD in the daily life, measured by a VAS, with the inflammation activity. | 28948412 |
| Inflammation | Altered Intercellular Communication | The results of the symptom index demonstrated a statistically significant correlation with the rapid calprotectin test, histological inflammation activity, and the VAS. | 28948412 |
| Inflammation | Altered Intercellular Communication | No correlations were found between the VAS and calprotectin or the histological inflammation activity. | 28948412 |
| Inflammation | Altered Intercellular Communication | The sensitivity of the combination index to detect active inflammation was slightly superior to fecal calprotectin alone. | 28948412 |
| Inflammation | Altered Intercellular Communication | The new symptom index and the combination index are simple, noninvasive means for distinguishing remission from active inflammation in colonic IBD. | 28948412 |
| Inflammation | Altered Intercellular Communication | In 64.8% of the procedures, the mucosa was inflamed; however, 14.7% did not show histological inflammation. | 28949435 |
| Inflammation | Altered Intercellular Communication | Endoscopic remission was observed in the other 35.2% of procedures; however, in biopsies 21.6% exhibited histological inflammation. | 28949435 |
| Inflammation, Wheezing, MS4A2 wt Allele, Comorbidity | Altered Intercellular Communication | We included very young consecutive children presenting with recurrent wheezing who had been evaluated for the severity of wheezing, associated atopic comorbidities, and tested for biomarkers of atopy and inflammation. | 28950434 |
| Inflammation, Viral respiratory infection | Altered Intercellular Communication | Association between the TT-genotype of IL-4 rs2070874 polymorphism and a severe phenotype of viral-induced wheeze further underlines the role IL-4 plays in the inflammation pathway leading to viral respiratory infections. | 28950434 |
| Hormone abnormality, Polycystic Ovary Syndrome | Altered Intercellular Communication | The drug is also associated with hormonal disorders, polycystic ovary and reduced fertility. | 28950817 |
| Inflammation, Psoriasis, Cardiovascular system | Altered Intercellular Communication | Psoriasis patients experience chronic systemic skin inflammation and develop cardiovascular comorbidities that shorten their lifespan. | 28951241 |
| Dermatitis, Neutrophilia (finding), Monocytosis, Luminal Carotid Thrombus | Altered Intercellular Communication | KC-Tie2 mice develop psoriasiform skin inflammation with increases in IL-23 and IL-17A and proinflammatory monocytosis and neutrophilia that precedes development of carotid artery thrombus formation. | 28951241 |
| Inflammation, Thrombosis | Altered Intercellular Communication | Skin inflammation; thrombosis clotting times; and percentage of splenic monocytes, neutrophils, and CD4 T cells were examined. | 28951241 |
| Inflammation, Psoriasis | Altered Intercellular Communication | Skin inflammation significantly improved in KC-Tie2 mice treated with each of the antibodies targeting IL-23, IL-17A, or IL-17RA, consistent with clinical efficacy observed in psoriasis patients. | 28951241 |
| Inflammation, Neutropenia | Altered Intercellular Communication | This decrease in skin inflammation paralleled decreases in splenic neutrophils (CD11b+Ly6G+) but not monocytes (CD11b+Ly6Chigh) or T cells (CD4+). | 28951241 |
| Inflammation | Altered Intercellular Communication | Subclass-specific IgG glycosylation is associated with markers of inflammation and metabolic health. | 28951559 |
| Inflammation, Cardiovascular Diseases | Altered Intercellular Communication | increased inflammation as assessed by C-reactive protein, low serum high-density lipoprotein cholesterol and high triglycerides, which are all known to indicate increased risk of cardiovascular disease. | 28951559 |
| Inflammation, Rheumatoid Arthritis | Altered Intercellular Communication | Characterization of neutrophil-to-lymphocyte ratio as a measure of inflammation in rheumatoid arthritis. | 28952205 |
| Inflammation | Altered Intercellular Communication | The neutrophil to lymphocyte ratio (NLR) is one of the well-recognized sensitive measures of inflammation. | 28952205 |
| Refractory anemias, Inflammation | Altered Intercellular Communication | In contrast to the traditional markers, NLR may serve as a less expensive and effective measure of inflammation in RA. | 28952205 |
| Inflammation, Thrombosis, Primary malignant neoplasm | Altered Intercellular Communication | The role of Protein Z (PZ) in conditions, such as thrombosis, inflammation or cancer, is under investigation. | 28952223 |
| Virus Diseases, Chronic inflammation, Malignant Neoplasms | Altered Intercellular Communication | This holistic approach to care includes detection of malignancies that are associated with certain viral infections, with chronic inflammation, and with lifestyle choices. | 28952428 |
| Early Hepatocellular Carcinoma | Altered Intercellular Communication | Inflammation-nutrition scope predicts prognosis of early-stage hepatocellular carcinoma after curative resection. | 28953624 |
| Inflammation, Panophthalmitis, Squamous cell carcinoma, Tuberculosis, Pulmonary, Endophthalmitis, CTCAE | Altered Intercellular Communication | Other frequent indications included endophthalmitis (6.3%), nonspecific inflammation (4.1%), squamous cell carcinoma (3.6%), panophthalmitis (3.4%), and phthisis bulbi (1.2%). | 28954020 |
| Granulomatous inflammation, Ulcer | Altered Intercellular Communication | Asynovial fluid culture yielded Mycobacterium tuberculosis, and a forearm ulcer biopsy showed granulomatous inflammation. | 28954084 |
| Inflammation, Bone necrosis | Altered Intercellular Communication | Histologically, persistent inflammation and extensive osteonecrosis were seen in group 4. | 28954199 |
| Inflammation | Altered Intercellular Communication | There was no other clinical involvement, biological inflammation, or autoantibodies. | 28954874 |
| Inflammation, Cholecystitis | Altered Intercellular Communication | This study indicated that the severe inflammation indicated by high CRP values during cholecystitis attacks predicts the need for an additional port. | 28954990 |
| Virus Diseases | Altered Intercellular Communication | While the pathogenesis of the disease is unknown, it is traditionally hypothesized that the viral infection occurs by neuronal transmission directly from peripheral sites. | 28956417 |
| Inflammation, Burn, CTCAE | Altered Intercellular Communication | We report a severe ocular burn case that illustrates in-office management to promote rapid re-epithelialization and reduce inflammation to restore ocular surface integrity. | 28957834 |
| Conjunctivitis | Altered Intercellular Communication | Examination revealed diffuse conjunctival inflammation and extensive corneal, conjunctival, and limbal epithelial defects in the left eye; hence, application of cryopreserved AM was performed. | 28957834 |
| Inflammation | Altered Intercellular Communication | Placement of three self-retained AMs over a 10-day period resulted in resolution of symptoms, reduction in inflammation, complete re-epithelialization of corneal and limbal defects, and improvement of visual acuity from 20/50 to 20/20. | 28957834 |
| Conjunctivitis | Altered Intercellular Communication | Intriguingly, areas of conjunctival inflammation not covered by the AM remained inflamed. | 28957834 |
| Inflammation | Altered Intercellular Communication | In this case of acute chemical burn, application of self-retained AM 24 hours after injury was effective in promoting ocular surface healing, reducing inflammation, and restoring visual acuity. | 28957834 |
| Inflammation, Acute pulmonary embolism | Altered Intercellular Communication | Comparison of acute and convalescent biomarkers of inflammation in patients with acute pulmonary embolism treated with systemic fibrinolysis vs. placebo. | 28957940 |
| Inflammation, Pulmonary Embolism, Venous Thromboembolism, vinyltriethoxysilane | Altered Intercellular Communication | : Previous studies have associated biomarkers indicative of acute inflammation with pulmonary embolism, which may amplify coagulation, inhibit fibrinolysis and increase risk of venous thromboembolism (VTE) recurrence. | 28957940 |
| Inflammation, Acute pulmonary embolism | Altered Intercellular Communication | Acute pulmonary embolism causes marked but transient inflammation, as demonstrated by the significant elevation in the inflammatory biomarkers at diagnosis, followed by their reduction in more than 80% of patients at 3-month follow-up. | 28957940 |
| Inflammation, Metabolic Syndrome X, Diabetes Mellitus | Altered Intercellular Communication | Clusterin (Clu), also known as apolipoprotein J (ApoJ), is a highly conserved disulfide-linked heterodimeric glycoprotein implicated in a great variety of physiological and pathophysiological processes including lipid transportation, tissue remodeling, senescence, cell interaction, stress response, inflammation, apoptosis, diabetes mellitus and metabolic syndrome. | 28958138 |
| Inflammation, Chronic heart failure | Altered Intercellular Communication | Utility of Growth Differentiation Factor-15, A Marker of Oxidative Stress and Inflammation, in Chronic Heart Failure: Insights From the HF-ACTION Study. | 28958347 |
| Arterial Stiffness, Inflammation, Glycation End Products, Advanced, Diabetes Mellitus, Non-Insulin-Dependent | Altered Intercellular Communication | High intake of dietary advanced glycation end-products is associated with increased arterial stiffness and inflammation in subjects with type 2 diabetes. | 28958695 |
| Diastolic dysfunction, Hypernatremia, Fibrosis Assessment, Inflammation | Altered Intercellular Communication | Osteoglycin prevents the development of age-related diastolic dysfunction during pressure overload by reducing cardiac fibrosis and inflammation. | 28958774 |
| Cardiac Hypertrophy, Fibrosis Assessment, Inflammation, Hypertensive heart disease | Altered Intercellular Communication | However, whether osteoglycin modulates cardiac hypertrophy, fibrosis or inflammation in hypertensive heart disease and during aging remains unknown. | 28958774 |
| Hypernatremia, Inflammation | Altered Intercellular Communication | Angiotensin-II-induced pressure overload increases cardiac osteoglycin expression, concomitant with the onset of inflammation and extracellular matrix deposition. | 28958774 |
| Diastolic dysfunction, Inflammation, Fibrosis Assessment | Altered Intercellular Communication | However, Angiotensin-II infusion in combination with aging resulted in exaggerated cardiac fibrosis and inflammation in the osteoglycin null mice as compared to wild-type mice, resulting in increased diastolic dysfunction as determined by magnetic resonance imaging. | 28958774 |
| Hypernatremia, Inflammation, Fibrosis Assessment, Diastolic dysfunction | Altered Intercellular Communication | In conclusion, osteoglycin expression is increased in the heart in response to pressure overload and its absence results in increased cardiac inflammation and fibrosis resulting in increased diastolic dysfunction. | 28958774 |
| palladium | Altered Intercellular Communication | Increasing evidence has suggested that the GABAergic neurotransmitter system is involved in the pathogenesis of PD. | 28960581 |
| Inflammation, Cachexia, Anorexia | Altered Intercellular Communication | Inflammation, use of loop diuretics, and cachexia are associated with an increased likelihood of anorexia in patients with HF, and patients with anorexia showed impaired functional capacity and poor outcomes. | 28960880 |
| Dermatitis | Altered Intercellular Communication | Long-term exposure to ultraviolet (UV) irradiation causes skin inflammation and aging. | 28961200 |
| Inflammation | Altered Intercellular Communication | Angiopoietin-like protein 2 (Angptl2) is a mediator of chronic inflammation that contributes to extracellular matrix remodeling. | 28962551 |
| Inflammation, selenium | Altered Intercellular Communication | Data on ACPA, smoking, SE, inflammation (C-reactive protein) and disease activity score in 28 joints (DAS28) was obtained from the EIRA database. | 28962582 |
| Inflammation | Altered Intercellular Communication | AAV severity was associated with markers reflecting organ involvement (TKT, CD93, and TNC) rather than inflammation. | 28962592 |
| Inflammation, Coronary Arteriosclerosis | Altered Intercellular Communication | Soluble levels and endogenous vascular gene expression of KLOTHO are related to inflammation in human atherosclerotic disease. | 28963437 |
| Inflammation, Atherosclerosis | Altered Intercellular Communication | Our study indicates an inverse interrelationship between inflammation and Klotho in atherosclerosis. | 28963437 |
| Inflammation, COL4A2 wt Allele | Altered Intercellular Communication | These findings, which should be validated through a larger study, suggest that inflammation plays an important role in mediating outcomes after ICH. | 28964648 |
| Kidney Failure, Chronic, Inflammation, Malnutrition, Atherosclerosis, Cardiovascular morbidity, Endothelial dysfunction | Altered Intercellular Communication | Inflammation and malnutrition play an important role in endothelial dysfunction, atherosclerosis and excessive cardiovascular morbidity and mortality in ESRD patients AIM OF THE STUDY: The primary objective is to determine the prevalence of inflammation, malnutrition and atherosclerosis in patients on maintenance haemodialysis. | 28964721 |
| Inflammation, Malnutrition, Atherosclerosis | Altered Intercellular Communication | Secondary objective was to determine the association for atherosclerosis with inflammation and malnutrition. | 28964721 |
| Inflammation, Malnutrition, Atherosclerosis | Altered Intercellular Communication | Atherosclerosis was present in 65.3%: 58.4% of patients had malnutrition and 43.6% had inflammation. | 28964721 |
| Inflammation, Malnutrition, Carotid Atherosclerosis | Altered Intercellular Communication | Inflammation (high serum CRP) and malnutrition (low serum albumin) in patients on haemodialysis are significantly associated with carotid atherosclerosis. | 28964721 |
| Inflammation | Altered Intercellular Communication | A panel of serum and urine biomarkers of inflammation and joint degradation were evaluated. | 28964890 |
| Degenerative polyarthritis | Altered Intercellular Communication | Consequently, ABT-981 may provide clinical benefit to patients with inflammation-driven OA. | 28964890 |
| Pancreatic carcinoma | Altered Intercellular Communication | Here, we reported that increased neurotransmitter adrenaline was associated with the poor survival in pancreatic cancer patients. | 28965949 |
| Inflammation | Altered Intercellular Communication | The prevalence of follicles, papillary inflammation and scarring were 33.6, 31.6, and 28.5%, respectively. | 28966918 |
| Communicable Diseases, Inflammation | Altered Intercellular Communication | In individuals with inflammation in the absence of infection the IFNG/IL22 and NK cell response was reduced, however, pro-inflammatory, growth and matrix factors remained upregulated and mucins were downregulated. | 28966918 |
| Inflammation | Altered Intercellular Communication | Interestingly, females appear more susceptible to developing papillary inflammation and scarring than males, even at this young age, despite comparable levels of C. trachomatis infection. | 28966918 |
| Respiratory distress, Pneumonitis | Altered Intercellular Communication | The club cell protein (CC-16) is a biomarker associated with respiratory distress and pulmonary inflammation. | 28967121 |
| Colorectal Carcinoma | Altered Intercellular Communication | How systemic inflammation-based prognostic scores such as the modified Glasgow Prognostic Score (mGPS) and neutrophil:lymphocyte ratio (NLR) differ across populations of patients with colorectal cancer (CRC) remains unknown. | 28967380 |
| Inflammation, Heart failure | Altered Intercellular Communication | Proteomic profiling identified several novel associations between proteins involved in apoptosis, inflammation, matrix remodelling, and fibrinolysis with incident heart failure in elderly individuals. | 28967680 |
| Inflammation | Altered Intercellular Communication | About 900 DMRs were found and their associated genes were significantly enriched in 32 pathways, the top ones of which were associated with insulin resistance and inflammation. | 28967791 |
| Inflammation, Rosacea, Chronic Kidney Diseases | Altered Intercellular Communication | Inflammation and oxidative stress are involved in the etiopathogenesis of rosacea and chronic kidney disease (CKD). | 28968402 |
| Ocular Hypertension, Inflammation, Uveitis | Altered Intercellular Communication | Ocular hypertension (OHT) caused by inflammation or corticosteroid treatment is a common complication of uveitis. | 28968412 |
| Inflammatory abnormality of the eye, Uveitis | Altered Intercellular Communication | K-115 decreased IOP in both inflammation- and corticosteroid-induced OHT associated with uveitis and played a synergistic role in reducing ocular inflammation in uveitis treatment. | 28968412 |
| vascular inflammations, Cerebrovascular accident | Altered Intercellular Communication | Myeloperoxidase plays a central role in initiation and progression of vascular inflammation, but prior studies linking myeloperoxidase with stroke risk have been inconclusive. | 28969386 |
| Cerebrovascular Disorders, Inflammation, Cerebrovascular accident | Altered Intercellular Communication | Furthermore, these results support a rationale for chronic inflammation as a potential modifiable stroke risk mechanism, and suggest that immune-targeted therapies could be useful for treatment and prevention of cerebrovascular disease. | 28969386 |
| Endothelium, Atherosclerosis | Altered Intercellular Communication | Current paradigms suggest atherosclerosis is a chronic, dynamic, inflammatory condition precipitated in response to endothelial injury from various environmental challenges. | 28969386 |
| vascular inflammations, Arterial Injury | Altered Intercellular Communication | Furthermore, liraglutide treatment suppressed hyperglycemia-enhanced vascular inflammation 7 days after arterial injury. | 28969637 |
| Inflammation, Rheumatoid Arthritis, Chronic Kidney Diseases, Cardiovascular Diseases | Altered Intercellular Communication | Chronic kidney disease, inflammation, and cardiovascular disease risk in rheumatoid arthritis. | 28969969 |
| Refractory anemias, Inflammation, Chronic Kidney Diseases | Altered Intercellular Communication | Recently, chronic kidney disease (CKD) was suggested to increase the risk of CVD in RA patients, and inflammation was identified as a critical, nontraditional CKD-associated risk factor for CVD. | 28969969 |
| Refractory anemias, Inflammation, Chronic Kidney Diseases | Altered Intercellular Communication | The coexistence of CKD and inflammation was associated with a higher risk of CVD than either condition alone in RA patients. | 28969969 |
| Inflammation, Cyclophosphamide/Vincristine/Dacarbazine Regimen, Chronic Kidney Diseases | Altered Intercellular Communication | Inflammation might increase the risk of CVD especially in patients with CKD. | 28969969 |
| Refractory anemias, Rheumatoid Arthritis, Cyclophosphamide/Vincristine/Dacarbazine Regimen, Cardiovascular Diseases | Altered Intercellular Communication | Rheumatoid arthritis (RA), a prototypic systemic autoimmune inflammatory condition, confers an increased risk of cardiovascular disease (CVD). | 28969969 |
| Inflammation, Fibrosis Assessment, Granuloma, Foreign-Body | Altered Intercellular Communication | The degree of chronic inflammation, fibrosis, foreign-body giant cell reactions, the number of capillary vessels and nerve fibers, and the presence or absence of adipose tissue were recorded. | 28970142 |
| Inflammation, Fibrosis Assessment, Giant Cells, Foreign-Body | Altered Intercellular Communication | In most cases, mild to moderate chronic inflammation with a mild degree of foreign-body giant cell reaction and minimal to mild fibrosis were found in explanted mesh specimens. | 28970142 |
| Inflammation, Pain Distress Question | Altered Intercellular Communication | Mast Cell-Intervertebral disc cell interactions regulate inflammation, catabolism and angiogenesis in Discogenic Back Pain. | 28970490 |
| Inflammation | Altered Intercellular Communication | Both FBX011 and TGIF1 are involved in TGF-b signalling, suggesting this pathway may be important in the transition from acute to chronic middle ear inflammation, and a potential molecular target. | 28970529 |
| Inflammation, Chronic Kidney Diseases | Altered Intercellular Communication | In patients with chronic kidney disease (CKD), microinflammation with an increased percentage of CD14+ /CD16++ inflammatory monocytes has been reported, even with no clinical evidence of inflammation. | 28971592 |
| Sporothrix, Autoimmune reaction, Inflammatory abnormality of the eye | Altered Intercellular Communication | Sporothrix infection should be included in the differential diagnosis for ocular inflammation, regardless of the presence or absence of autoimmune comorbidities and whether the patient resides in an endemic area or not. | 28972025 |
| Inflammation, Erythema | Altered Intercellular Communication | Finally, selected formulations were also analyzed in an erythema model for testing formulations on UV-induced inflammation. | 28972949 |
| Inflammation, Prediabetes syndrome, Cardiovascular Diseases | Altered Intercellular Communication | We investigated diastolic function and its association with markers of glycation and inflammation related to cardiovascular disease in patients with prediabetes. | 28973588 |
| Inflammation, Plaque, Atherosclerotic | Altered Intercellular Communication | Altogether, these results show that adequate endothelial autophagic flux under high SS limits atherosclerotic plaque formation by preventing endothelial apoptosis, senescence, and inflammation. | 28973855 |
| Inflammation, Hematoma, Thrombosis, Hemorrhage, Pseudoaneurysm | Altered Intercellular Communication | In-hospital observation showed vascular perforation/bleeding in 4.7%, proximal hematoma in 9.3%, distal hematoma in 4.7%, pseudoaneurysm in 1.2%, thrombosis in 1.2%, puncture-site bleeding in 3.5%, and local inflammation in 1.2%. | 28974660 |
| Inflammation, Obesity | Altered Intercellular Communication | Data herein show that distinct protein profiles identify specific peptides belonging to lipid metabolism and inflammation processes that are associated with obesity and vitamin D deficiency. | 28974732 |
| Hereditary Diseases, Inflammation, Brucellosis | Altered Intercellular Communication | Familial Mediterranean fever is a hereditary disease, characterized by recurrent episodes of inflammation. | 28975396 |
| Inflammation, Fibrosis Assessment, Fatty degeneration, Non-alcoholic Fatty Liver Disease, Liver Cirrhosis | Altered Intercellular Communication | Regression analysis revealed that G allele odds of having cirrhosis was 3.9 times compared to C. The G allele was also significantly associated with steatosis, lobular inflammation, NAFLD activity score, and fibrosis. | 28975533 |
| Inflammation | Altered Intercellular Communication | Both implant and teeth developed similar increased response of inflammation at 14 days compared to day 0: BoPs of 4.2+-1.8 (P=0.06) and BoPs of 3.1+-2.2 (P=0.048) for implant and tooth, respectively. | 28975772 |
| Refractory anemias, Inflammation, MIR20A gene | Altered Intercellular Communication | MiR-20a plays a role in mediating synovial inflammation in RA. | 28975975 |
| Inflammation | Altered Intercellular Communication | Patients with cHepC had increased inflammation compared to the healthy controls. | 28976873 |
| Kidney Failure, Chronic, Inflammation | Altered Intercellular Communication | End-stage renal disease (ESRD) patients had higher levels of inflammation markers (NLR, IgG, CRP and YKL-40) and lower HCV RNA levels, HAI and FS compared to non-uremic patients. | 28976873 |
| Inflammation, Primary malignant neoplasm | Altered Intercellular Communication | Cytoplasmic chromatin triggers inflammation in senescence and cancer. | 28976970 |
| Inflammation, Primary malignant neoplasm, Destruction of tissue | Altered Intercellular Communication | Here we show that cytoplasmic chromatin activates the innate immunity cytosolic DNA-sensing cGAS-STING (cyclic GMP-AMP synthase linked to stimulator of interferon genes) pathway, leading both to short-term inflammation to restrain activated oncogenes and to chronic inflammation that associates with tissue destruction and cancer. | 28976970 |
| Inflammation, Ionizing radiation | Altered Intercellular Communication | Mice deficient in STING show impaired immuno-surveillance of oncogenic RAS and reduced tissue inflammation upon ionizing radiation. | 28976970 |
| Inflammatory disorder | Altered Intercellular Communication | Targeting the cytoplasmic chromatin-mediated pathway may hold promise in treating inflammation-related disorders. | 28976970 |
| Inflammation, ETV3 wt Allele | Altered Intercellular Communication | Although the precise mechanisms are still unclear, irisin, RBP-4, adiponectin and PTX-3 are hallmarks of the MetS, which is related to low-grade inflammation. | 28977161 |
| Inflammation, Rheumatoid Arthritis | Altered Intercellular Communication | Ultrasound of the hand is sufficient to detect subclinical inflammation in rheumatoid arthritis remission: a post hoc longitudinal study. | 28978340 |
| Refractory anemias, Inflammation, Rheumatoid Arthritis | Altered Intercellular Communication | Ultrasound (US) is a sensitive method for detecting joint/tendon inflammation in patients with rheumatoid arthritis (RA). | 28978340 |
| Refractory anemias, Inflammation | Altered Intercellular Communication | Subclinical inflammation is often found in patients with RA in composite score remission. | 28978340 |
| Refractory anemias, Inflammation | Altered Intercellular Communication | The purpose of the present study was to explore whether US of only the hands is sufficient to identify subclinical inflammation in patients with established RA in clinical remission. | 28978340 |
| Refractory anemias, Inflammation | Altered Intercellular Communication | US examination performed only of the hands captured >= 90% of patients with subclinical inflammation and could be feasible for assessing bDMARD-treated patients with RA in remission. | 28978340 |
| Inflammation, Small bowel obstruction | Altered Intercellular Communication | A large enterolith was found to be impacted in the jejunum just distal to the area of inflammation resulting in small bowel obstruction. | 28978602 |
| Urolithiasis, Pyelonephritis, Nephritis, Hydronephrosis | Altered Intercellular Communication | BACKGROUND Xanthogranulomatous pyelonephritis (XP) is an extremely rare, severe, atypical form of chronic renal parenchymal inflammation accompanied by hydronephrosis and/or urolithiasis. | 28978905 |
| Necrotizing granulomatous inflammation | Altered Intercellular Communication | Significant CD68-positive cell infiltrations and scattered foam cells arranging the numerous foci of granuloma inflammation were noticed. | 28978905 |
| ARCN1 gene, Inflammation | Altered Intercellular Communication | Differences in systemic inflammation between cigarette and biomass smoke-induced COPD. | 28979110 |
| ARCN1 gene, Inflammation | Altered Intercellular Communication | It is known that biomarkers of systemic inflammation are raised in COPD caused by tobacco (T-COPD) compared with healthy controls, but there is less information on the inflammatory status of subjects with COPD caused by biomass smoke (B-COPD). | 28979110 |
| ARCN1 gene, Inflammation | Altered Intercellular Communication | Both types of COPD are associated with high levels of systemic inflammation biomarkers. | 28979110 |
| Airway structure | Altered Intercellular Communication | Cell count in induced sputum is a noninvasive biomarker to assess airway inflammation phenotypes. | 28979112 |
| Inflammation, Fibrosis Assessment, Retractile Mesenteritis | Altered Intercellular Communication | A biopsy was performed, revealing benign chronic inflammation, fibrosis and IgG4-positive plasmocytes consistent with sclerosing mesenteritis. | 28979630 |
| Inflammatory disorder | Altered Intercellular Communication | Complement factor 5a (C5a) may be involved in many inflammation disorders. | 28981167 |
| Inflammation, Carcinoma of lung | Altered Intercellular Communication | A prospective study of immune and inflammation markers and risk of lung cancer among female never smokers in Shanghai. | 28981818 |
| Inflammation, Carcinoma of lung | Altered Intercellular Communication | Here, we have carried out the first large study of circulating inflammation markers and lung cancer risk among female never smokers in Shanghai. | 28981818 |
| Inflammation, Carcinoma of lung | Altered Intercellular Communication | Markers involved in various aspects of the immune response were associated with subsequent lung cancer risk, implicating inflammation in the etiology of lung cancer among female never smokers. | 28981818 |
| Inflammation, No metabolic abnormalities, Pancreatitis | Altered Intercellular Communication | Emerging evidence shows that chronic low-grade inflammation and changes in markers of innate immunity are implicated in a range of metabolic abnormalities following an episode of acute pancreatitis. | 28982582 |
| Inflammation, Primary malignant neoplasm, Communicable Diseases, Anal carcinoma, Postoperative Complications, Inflammatory disorder | Altered Intercellular Communication | Abdominoperineal resection (APR) has been performed for lower rectal cancer, anal cancer and inflammatory diseases, but is associated with postoperative complications such as inflammation of pelvic dead space or perineal wound infection. | 28982899 |
| Inflammation, Infection | Altered Intercellular Communication | None developed postoperative dead space inflammation or perineal wound infections. | 28982899 |
| Inflammation | Altered Intercellular Communication | A picture of periportal inflammation was still detected in 4 cases, with no evidence of inflammatory lesions in the remaining cases. | 28983074 |
| Inflammation, Carcinogenesis | Altered Intercellular Communication | Adipokines, and other inflammation molecules linked to adiposity, are suspected to be involved in breast carcinogenesis, however prospective findings are inconclusive. | 28983080 |
| Inflammation, Breast Carcinoma | Altered Intercellular Communication | These findings constitute further evidence that inflammation plays a role in breast cancer. | 28983080 |
| Inflammation | Altered Intercellular Communication | Identified DASGs were associated with myogenesis, adipogenesis, protein ubiquitination, and inflammation. | 28984045 |
| Blood Clot | Altered Intercellular Communication | Fifty-eight cases (41%) had findings warranting further analysis, including alterations in glomerular matrix and/or cellularity, atypical or pigmented casts, thrombi, tubulointerstitial or vascular inflammation, or deposition of amorphous material. | 28984299 |
| Inflammation, Lymphoma | Altered Intercellular Communication | Purpose To analyze the frequency and distribution of low-signal-intensity regions (LSIRs) in lymphoma lesions and to compare these to fluorodeoxyglucose (FDG) uptake and biologic markers of inflammation. | 28985135 |
| methyldopa, Inflammation | Altered Intercellular Communication | Inflammation is a key pathogenic factor in age-related macular degeneration (AMD). | 28985220 |
| Inflammation, Pathology, Nerve Degeneration | Altered Intercellular Communication | Although each disease has particular pathologies and symptoms, accumulated evidence points to similar mechanisms of neurodegeneration, including inflammation, oxidative stress, and protein aggregation. | 28985333 |
| Inflammation | Altered Intercellular Communication | CD4+CXCR5+ T cells from CAD patients also demonstrated more potent capacity to stimulate B cell inflammation than those from healthy individuals. | 28985621 |
| Atherosclerosis | Altered Intercellular Communication | The major contributing event is atherosclerosis, which is a progressive inflammatory condition resulting in the thickening of the arterial wall and the formation of atheromatous plaques. | 28985621 |
| Inflammation, De Quervain Disease, Tenosynovitis | Altered Intercellular Communication | De Quervain's tenosynovitis is a repetitive strain injury involving synovial inflammation of the tendons of the first extensor compartment of the wrist. | 28985641 |
| Inflammation, Appendicitis, CTCAE | Altered Intercellular Communication | The exact role of this parasite in acute appendicitis is controversial as usually resected specimens show no evidence of histological inflammation. | 28985767 |
| Inflammation, Neoplasms, Communicable Diseases, Traumatic injury, Glaucoma, CTCAE | Altered Intercellular Communication | The leading pathologic causes of eye removal were neoplasm (36%), glaucoma (21%), infection or inflammation (17%), and trauma (16%). | 28985809 |
| Inflammation, Pathology, Neoplasms, Traumatic injury, Glaucoma, CTCAE | Altered Intercellular Communication | Common pathologies included glaucoma, neoplasms, infection/inflammation, and trauma. | 28985809 |
| Acute myocardial infarction, vascular inflammations, Thrombosis | Altered Intercellular Communication | The alarmin family member myeloid-related protein (MRP)-14 (S100A9), which has been identified by platelet transcriptional profiling as an acute myocardial infarction gene, regulates vascular inflammation and thrombosis. | 28986057 |
| Inflammation, Thrombosis, GDC AJCC Clinical Stage Terminology | Altered Intercellular Communication | MRP-8/14 is positioned as a unique biomarker at the interface of inflammation and thrombosis in ACS. | 28986057 |
| Inflammation, atherosclerotic | Altered Intercellular Communication | We found altered relationships between PC and lysoPC profiles, inflammation, and arterial function in atherosclerotic patients, compared to healthy subjects. | 28986077 |
| Airway structure, ARCN1 gene, Bronchoconstriction | Altered Intercellular Communication | Medicines targeting bronchoconstriction and airway inflammation are the current mainstays of COPD therapy. | 28986203 |
| Inflammation, Lung Injury, mucus secretion | Altered Intercellular Communication | Previous studies have indicated that inhalation of unfractionated heparin (UFH) treats local inflammation, mucus hypersecretion and lung injury, without systemic anticoagulation, and is safe. | 28986203 |
| Inflammation, Idiopathic Pulmonary Fibrosis | Altered Intercellular Communication | Idiopathic pulmonary fibrosis (IPF) is characterized by a disturbed pulmonary redox balance associated with inflammation. | 28987380 |
| Inflammation, Idiopathic Pulmonary Fibrosis | Altered Intercellular Communication | Collectively, our findings implicate that IPF patients may benefit from the use of quercetin to restore the disturbed redox balance and reduce inflammation. | 28987380 |
| Inflammation, Fatty degeneration, Alcoholic Liver Diseases, Liver Cirrhosis | Altered Intercellular Communication | Chronic, excessive alcohol consumption leads to alcoholic liver disease (ALD) characterized by steatosis, inflammation, and eventually cirrhosis. | 28987423 |
| Inflammation, Fatty degeneration | Altered Intercellular Communication | Mice given injections of the anti-MIR122 before ethanol feeding had increased steatosis, inflammation, and serum levels of alanine aminotransferase compared with mice given a control vector. | 28987423 |
| carotid disease | Altered Intercellular Communication | Circulating inflammation-resolving lipid mediators RvD1 and DHA are decreased in patients with acutely symptomatic carotid disease. | 28987721 |
| Resolvin | Altered Intercellular Communication | Resolvins are endogenous inflammation-resolving lipid mediators that are induced by inflammatory insults. | 28987721 |
| Inflammation | Altered Intercellular Communication | We hypothesized that increased inflammatory activation, manifested as increased GlycA, a novel biomarker of global inflammation, would be evident in Palestinians. | 28987777 |
| Inflammation, Cardiovascular Diseases, Diabetes Mellitus | Altered Intercellular Communication | This propensity to inflammation may be a driver of the higher risk of cardiovascular disease, insulin resistance and diabetes observed in this population. | 28987777 |
| Inflammation, Arthropathy | Altered Intercellular Communication | The underlying mechanism of joint dysfunction involves increased oxidative stress, inflammation, high levels of cartilage extracellular matrix degrading proteases and decline in autophagy-a mechanism of cellular defense. | 28987943 |
| Trachoma , Perifolliculitis | Altered Intercellular Communication | When analyzed by the presence or absence of individual WHO simplified system signs of active trachoma, trachomatous inflammation-follicular cases constituted18% (95% CI: 15.9-20.2%), while 4.7% (95% CI: 3.6-5.8%) were trachomatous inflammation-intense cases. | 28988540 |
| Inflammation, Metabolic Diseases, Cardiovascular Diseases, Diabetes Mellitus, Virus Diseases | Altered Intercellular Communication | These "healthy" components of our diet are often referred to as nutraceuticals and they can prevent/suppress: aging, bacterial, fungal and viral infections, diabetes, inflammation, metabolic disorders and cardiovascular diseases and have other health-enhancing effects. | 28988970 |
| Eosinophilic esophagitis, Esophagitis | Altered Intercellular Communication | Comparison of endoscopy and radiographic imaging for detection of esophageal inflammation and remodeling in adults with eosinophilic esophagitis. | 28989006 |
| Esophagitis, "Extra-osseous Ewings sarcoma | Altered Intercellular Communication | Eosinophil predominant mucosal inflammation is central to the diagnosis and activity assessment of eosinophilic esophagitis (EoE). | 28989006 |
| Esophagitis | Altered Intercellular Communication | The aim of this study was to compare upper endoscopy (EGD) with barium upper GI study (UGI) for the detection of esophageal inflammation and remodeling in adults with EoE. | 28989006 |
| Inflammation, Cerebrovascular accident, Atherosclerosis | Altered Intercellular Communication | Stroke caused by atherosclerosis remains a leading cause of morbidity and mortality worldwide, associated with carotid plaque rupture and inflammation progression. | 28990089 |
| Inflammation | Altered Intercellular Communication | The hormonal background may be involved in inappropriate inflammation and increased stenosis susceptibility. | 28990664 |
| Inflammation | Altered Intercellular Communication | The hormonal background may be involved in inappropriate inflammation and increased stenosis susceptibility. | 28990664 |
| Necrosis with inflammation | Altered Intercellular Communication | The serum concentrations of protective marker adiponectin and bone necrosis inflammation factor IL-33 concentrations were also examined. | 28990818 |
| Granulomatous inflammation | Altered Intercellular Communication | Histopathological evaluation of pericardial tissue revealed granulomatous inflammation. | 28990950 |
| Inflammation, Ulceration, CTCAE, Granuloma | Altered Intercellular Communication | There were no differences in those 7 patients and the remaining 28 in terms of diagnosis at colectomy, primary pouch symptoms, prepouch inflammation, ulceration, or granulomas at endoscopy. | 28991085 |
| Inflammation, Glaucoma, CTCAE | Altered Intercellular Communication | The VAO, glaucoma, and inflammation were comparable 12 months postoperatively. | 28991614 |
| Inflammation, Infection, Ischemic stroke | Altered Intercellular Communication | Previous infections could increase the risk of ischemic stroke by an activation of systemic inflammation. | 28991723 |
| Inflammation, Fibrosis Assessment, Pancreatic carcinoma | Altered Intercellular Communication | Fatty Acid-Mediated Stromal Reprogramming of Pancreatic Stellate Cells Induces Inflammation and Fibrosis That Fuels Pancreatic Cancer. | 28991878 |
| Inflammation, Fibrosis Assessment, Carcinogenesis, Pancreatic carcinoma | Altered Intercellular Communication | Inflammation and fibrosis levels were increased in pancreatic cancer specimens, supporting the in vitro observations and suggesting that PSCs contribute to pancreatic carcinogenesis. | 28991878 |
| Rheumatoid Arthritis | Altered Intercellular Communication | Arterial Inflammation Detected With 18 F-Fluorodeoxyglucose-Positron Emission Tomography in Rheumatoid Arthritis. | 28992382 |
| Inflammation, Cardiovascular Diseases, Refractory anemias, Cyclophosphamide/Vincristine/Dacarbazine Regimen, Rheumatoid Arthritis | Altered Intercellular Communication | In addition to traditional risk factors, excess cardiovascular disease (CVD) in rheumatoid arthritis (RA) is attributed to enhanced vascular and/or systemic inflammation. | 28992382 |
| Refractory anemias, Inflammation, Miller Dieker syndrome | Altered Intercellular Communication | RA patients underwent cardiac FDG-PET/CT, with aortic inflammation assessed by quantification of FDG uptake in the ascending aorta, calculated as the mean and maximum (max) standardized uptake value (SUV) of the entire ascending aorta and of its most diseased segment (SUV MDS). | 28992382 |
| Inflammation, Genus staphylococcus, Demographics Domain | Altered Intercellular Communication | Staphylococcus and chronic hemodialysis were more prevalent in patients with DM, and these patients had greater preoperative inflammation levels and worse renal function than patients without DM. | 28992971 |
| Airway structure, Wheezing | Altered Intercellular Communication | Recurrent wheeze and its relationship with lung function and airway inflammation in preschool children: a cross-sectional study in South Korea. | 28993393 |
| Inflammation, Wheezing | Altered Intercellular Communication | Relationship between recurrent wheeze and airway function and inflammation in preschool children is not fully known. | 28993393 |
| Asthma, AHR wt Allele, MS4A2 wt Allele | Altered Intercellular Communication | To investigate the relationship between recurrent wheeze and airway inflammation, lung function, airway hyper-reactivity (AHR) and atopy in preschool children. | 28993393 |
| Airway structure, Wheezing, AHR wt Allele, MS4A2 wt Allele | Altered Intercellular Communication | Recurrent wheeze in preschool children may be associated with airway inflammation and diminished airway function, but not with AHR or atopy. | 28993393 |
| Inflammation, Disease | Altered Intercellular Communication | Levels of proinflammatory (TNF A) and anti-inflammatory (IL-10) cytokines play a key role in the progression of inflammation as well as cancer disease. | 28993831 |
| Inflammation, Infection, Chronic disease, Fatigue | Altered Intercellular Communication | Systemic inflammation may play a role in the development of idiopathic fatigue, that is, fatigue not explained by infections or diagnosed chronic illness, but this relationship has never been investigated in community studies including the entire adult age span. | 28994356 |
| Degenerative polyarthritis, Inflammation | Altered Intercellular Communication | Five patients showed inflammation in joints pre-damaged by osteoarthritis. | 29018908 |
| Inflammation, Fracture | Altered Intercellular Communication | While diet is a potential source of inflammation, little is known about the impact of inflammatory diet on fractures. | 29018920 |
| Inflammation, Retinitis Pigmentosa, polychondritis | Altered Intercellular Communication | Relapsing polychondritis (RP) is a rare collagen disease characterized by inflammation and destruction of cartilage throughout the body. | 29019876 |
| Inflammatory abnormality of the eye, Arthritis, Chondritis of pinna, Retinitis Pigmentosa | Altered Intercellular Communication | Based on the auricle biopsy results and the three presenting symptoms (bilateral auricular chondritis, inflammatory arthritis and ocular inflammation), her condition was diagnosed as RP. | 29019876 |
| Inflammation, Metabolic Syndrome X, MS gene | Altered Intercellular Communication | Leptin and adiponectin have opposite effects on subclinical inflammation and insulin resistance, both involved in the development of metabolic syndrome (MS). | 29020116 |
| Intraocular inflammation | Altered Intercellular Communication | Worse initial visual acuity and severe intraocular inflammation at first presentation were equally associated with poor visual outcome in the multivariate model (adjusted odds ratio, 20.32; 95% confidence interval [1.12-357.45]; P = 0.040). | 29020471 |
| Intraocular inflammation | Altered Intercellular Communication | Poor initial visual acuity and severe intraocular inflammation at the initial presentation are predictors of poor visual outcome. | 29020471 |
| Inflammation, Hemorrhage, Specimen Reject Reason - Clotting | Altered Intercellular Communication | Histologic evaluation demonstrated complete endothelial coverage of the device by 30 days without evidence of bleeding, clotting, or inflammation. | 29020709 |
| Diabetic Nephropathy, Tumor necrosis, Nephritis | Altered Intercellular Communication | Consequently, hEC-SOD recovered from systemic and renal inflammation and apoptosis, as reflected by the decreases of serum and renal monocyte chemoattractant protein-1 and tumor necrosis factor-a levels and increases of BCL-2/BAX ratio in diabetic kidney. | 29020797 |
| Inflammation, Primary malignant neoplasm, Diarrhea, Bothered by Vomiting, Gastrointestinal mucositis, Abdominal Pain, Nausea | Altered Intercellular Communication | Although these forms of treatment damage rapidly dividing cancer cells, they are also toxic to the cells of the gastrointestinal tract, leading to inflammation of the mucosal layer (mucositis) and causing nausea, vomiting, diarrhea, and abdominal pain. | 29020798 |
| Suppurative inflammation | Altered Intercellular Communication | His first presentation showed moderate intracameral and intravitreous purulent inflammation with a best corrected vision of counting fingers. | 29020920 |
| Inflammation, Obesity | Altered Intercellular Communication | Limited data on whether physical activity modulates inflammatory status and counteracts obesity and insulin resistance associated low-grade inflammation exist. | 29020958 |
| Lymphoid Tissue, Inappropriate ADH Syndrome | Altered Intercellular Communication | Syndrome of Inappropriate Antidiuretic Hormone Secretion in a Patient with Mucosa-associated Lymphoid Tissue Lymphoma. | 29021471 |
| Inflammation, Arthritis | Altered Intercellular Communication | Microflow imaging: New Doppler technology to detect low-grade inflammation in patients with arthritis. | 29022101 |
| Inflammation, Arthritis | Altered Intercellular Communication | To assess the efficacy of microvascular imaging in detecting low-grade inflammation in arthritis compared with Power Doppler ultrasound (PDUS). | 29022101 |
| Inflammation, Arthritis | Altered Intercellular Communication | This allows detection of low grade inflammation not visualised with Power Doppler in patients with arthritis. | 29022101 |
| Inflammation | Altered Intercellular Communication | * SMI can detect low-grade inflammation not seen with Power Doppler. | 29022101 |
| Inflammation, unencapsulated part of cell | Altered Intercellular Communication | The density of lymphatic vessels and gene expressions related to lymphatic vessel, inflammation and proliferation were increased in non-encapsulated lipoma. | 29022421 |
| Inflammation, Thrombosis | Altered Intercellular Communication | In protocol 1, we evaluated markers of inflammation, thrombosis, and conduit artery endothelial function in subjects on non-ATV containing regimens. | 29023508 |
| Anxiety, CTCAE 3.0, Epilepsy | Altered Intercellular Communication | GABAergic neurotransmission in the amygdala contributes to the regulation of emotional processes in anxiety, stress, reward, mnestic functions, addiction, and epilepsy. | 29023704 |
| Xanthogranulomatous inflammation, IgG4-Related Sclerosing Disease | Altered Intercellular Communication | XGCs with IgG4-positive cell infiltration are considered to be mimickers, as xanthogranulomatous inflammation generally contradicts a diagnosis of IgG4-related disease and is weakly associated with other typical organ manifestations of IgG4-related disease. | 29023932 |
| Inflammation, Osteitis | Altered Intercellular Communication | Maxillo-facial CT and MRI showed inflammation of soft tissues and muscles without initial signs of osteitis, thus noncontributive to the diagnosis. | 29024750 |
| Dental Plaque | Altered Intercellular Communication | Our data suggests that other pathways than the inflammation-pathway are involved in plaque vulnerability and poor outcome in patients with decreased kidney function. | 29024865 |
| Hyperglycemia, Inflammation, Diabetes Mellitus, Non-Insulin-Dependent | Altered Intercellular Communication | The anti-inflammatory function of HDL is impaired in type 2 diabetes: role of hyperglycemia, paraoxonase-1 and low grade inflammation. | 29025405 |
| Hyperglycemia, Inflammation | Altered Intercellular Communication | The HDL anti-inflammatory capacity is substantially impaired in T2DM, at least partly attributable to the degree of hyperglycemia, decreased PON-1 activity and enhanced low grade chronic inflammation. | 29025405 |
| ARCN1 gene, Inflammation | Altered Intercellular Communication | Impact and associations of eosinophilic inflammation in COPD: analysis of the AERIS cohort. | 29025891 |
| ARCN1 gene, Inflammation, Chronic Obstructive Airway Disease | Altered Intercellular Communication | Eosinophilic inflammation in chronic obstructive pulmonary disease (COPD) predicts response to treatment, especially corticosteroids. | 29025891 |
| ARCN1 gene, Inflammation, Exacerbation | Altered Intercellular Communication | We studied the nature of eosinophilic inflammation in COPD prospectively to examine the stability of this phenotype and its dynamics across exacerbations, and its associations with clinical phenotype, exacerbations and infection.127 patients aged 40-85 years with moderate to very severe COPD underwent repeated blood and sputum sampling at stable visits and within 72 h of exacerbation for 1 year.Blood eosinophils >=2% was prevalent at baseline, and predicted both predominantly raised stable-state eosinophils across the year (area under the curve 0.841, 95% CI 0.755-0.928) and increased risk of eosinophilic inflammation at exacerbation (OR 9.16; p<0.001). | 29025891 |
| ARCN1 gene, Bacterial Infections, Eosinophilic inflammation | Altered Intercellular Communication | Bacterial infection at exacerbation was highly seasonal (winter versus summer OR 4.74; p=0.011) in predominantly eosinophilic patients.Eosinophilic inflammation is a common and stable phenotype in COPD. | 29025891 |
| Inflammation, Ulcerative Colitis | Altered Intercellular Communication | In non-inflamed UC (QUC) keratins, vimentin, and focal adhesion kinase (7) increased, whereas vinculin and de-tyrosinated a-tubulin decreased; inflammation (IUC) exacerbated molecular changes, being collagen type VI alpha 1 chain (COL6A1), tenascin-C and vimentin increased. | 29027377 |
| Refractory anemias, Inflammation | Altered Intercellular Communication | RA patients with positive anti-CCP antibodies had higher degrees of inflammation and disease activity as indicated by laboratory results, which likely contributed to their higher rates of healthcare utilization, joint erosion, and proportions of RA treatment. | 29027497 |
| TNF protein, human, Inflammation, Psoriasis vulgaris | Altered Intercellular Communication | Elevated levels of the biomarkers of inflammation (TNF-a, CRP, and IL-6) and the indicators of apoptosis (cfDNA, circulating nucleosomes) proved that exacerbated psoriasis vulgaris is associated with a high degree of systemic inflammatory responses and dysregulated apoptotic pathways. | 29027583 |
| Inflammation, Pustular psoriasis | Altered Intercellular Communication | Based on recent experimental data on the biology of ZIKV infection in the cutaneous environment, we speculate that ZIKV may have directly triggered the development of generalized pustular psoriasis by stimulation of keratinocyte-derived mediators of inflammation and a polyfunctional T-cell driven immune reaction in the cutaneous milieu. | 29027743 |
| Inflammation, Endocrine System Diseases | Altered Intercellular Communication | Inflammation and endocrine disorders are considered as major pathogenic factors of coronary atherosclerotic disease (CAD). | 29028483 |
| Inflammation, Nephritis, ENL Protein, Neuritis, Osteitis, Skin lesion, Lymphadenitis, Dactylitis, Arthritis, Orchitis | Altered Intercellular Communication | ENL is associated with clinical features such as skin lesions, neuritis, arthritis, dactylitis, eye inflammation, osteitis, orchitis, lymphadenitis and nephritis. | 29028793 |
| Colitis | Altered Intercellular Communication | Furthermore, BGM and EL-NE biomarkers were highly associated with colon inflammation in CD patients. | 29028807 |
| Inflammation | Altered Intercellular Communication | Formation of type V collagen is related to the level of inflammation in CD and may reflect disease activity in CD. | 29028807 |
| Metabolic Syndrome X | Altered Intercellular Communication | Electronegative Low-Density Lipoprotein L5 Induces Adipose Tissue Inflammation Associated With Metabolic Syndrome. | 29029093 |
| Inflammation | Altered Intercellular Communication | To investigate the role of L5 in the mechanism of adipose tissue inflammation associated with MetS. | 29029093 |
| Inflammation | Altered Intercellular Communication | L5 induces adipose inflammation through LOX-1 by promoting macrophage maturation and infiltration into adipose tissue. | 29029093 |
| vascular inflammations, Sleep Apnea, Obstructive, Coronary Artery Disease, Osage language | Altered Intercellular Communication | Obstructive sleep apnea (OSA) and enhanced vascular inflammation coexist in patients with coronary artery disease (CAD). | 29029237 |
| Inflammation, Fibrosis Assessment | Altered Intercellular Communication | Liver parenchyma adjacent to the treated lesion showed inflammation followed by fibrosis, without significant change in hepatic function. | 29029891 |
| Inflammation, Musculoskeletal Pain | Altered Intercellular Communication | Whole-body cryotherapy (WBC), which consists of a short exposure to very cold and dry air in special 'cryo-chambers', is believed to reduce inflammation and musculoskeletal pain as well as improve athletes' recovery. | 29030365 |
| Inflammation | Altered Intercellular Communication | MicroRNA Signature of Cigarette Smoking and Evidence for a Putative Causal Role of MicroRNAs in Smoking-Related Inflammation and Target Organ Damage. | 29030400 |
| Inflammation, Damage | Altered Intercellular Communication | Our results highlight smoking-associated microRNAs and are consistent with the hypothesis that smoking-associated microRNAs serve as mediators of smoking-induced inflammation and target organ damage. | 29030400 |
| Inflammation, Fatty infiltration | Altered Intercellular Communication | TIRM hyperintense areas, suggesting inflammation, were found in 3.5% of all muscles, with and without fatty infiltration. | 29030457 |
| Synapses, "Alzheimers Disease | Altered Intercellular Communication | We show that downregulation of RBFOX1 leads to destabilization of mRNAs encoding for synaptic transmission proteins, which may contribute to the loss of synaptic function in Alzheimer's disease. | 29030541 |
| Inflammation | Altered Intercellular Communication | Together, our results demonstrated that CD bacteria could promote Th1/Th17 inflammation in a host factor-independent fashion. | 29031634 |
| Inflammation | Altered Intercellular Communication | Chronic inflammation is an important component of intervertebral disc (IVD) degeneration, but there is limited knowledge about the identity and source of inflammatory cells involved with the degenerative processes. | 29031872 |
| Deficit, Inflammation | Altered Intercellular Communication | Elderly residents of long-term care commonly exhibit a number of age-related health deficits, including impaired physical and cognitive function, chronic illnesses, and chronic inflammation. | 29032243 |
| Inflammation, Psychiatric | Altered Intercellular Communication | Although aberrant expression of cytokines such as IL-1B and IFNG in blood from psychiatric patients supports a role of inflammation in the pathogenesis of the disease, little is known about mechanisms underlying their regulation. | 29032575 |
| Seizures, Inflammation, Disease | Altered Intercellular Communication | Our data shed further light on the potential role of inflammation, and more particularly inflammatory lncRNAs, in SZ and BP diseases and their pharmacological treatment. | 29032575 |
| Granulomatous inflammation, Neoplasms | Altered Intercellular Communication | Only one GCT had a diameter of <5 mm, and this was a regressed tumour within an 18-mm area of granulomatous inflammation. | 29032579 |
| Blepharitis, Inflammation, Corneal Infection | Altered Intercellular Communication | Age was a significant factor to be a case of corneal infection or inflammation [Exp (B)was 0.918, p=0.030], MGD and blepharitis was found to be significantly associated with being a case of SPK [Exp(B)was2.276, p=0.047]. | 29033270 |
| Pleurisy, Pseudotumor, Autoimmune Chronic Hepatitis | Altered Intercellular Communication | IgG4-related Lung Pseudotumor and Pleural Inflammation with Autoimmune Hepatitis. | 29033427 |
| Pleurisy, Autoimmune Chronic Hepatitis, Biopsy of pleura (procedure) | Altered Intercellular Communication | After pleural and liver biopsy procedures, he was conclusively diagnosed with IgG4-related lung pseudotumor and pleural inflammation with autoimmune hepatitis. | 29033427 |
| Inflammation, Bipolar Disorder | Altered Intercellular Communication | There is a large extant literature on the association between depressive symptoms and inflammation. | 29034558 |
| Inflammation, Bipolar Disorder | Altered Intercellular Communication | Temperament provides a more robust predictor of later inflammation than depressive symptoms. | 29034558 |
| Steatohepatitis, Inflammation | Altered Intercellular Communication | The outcome variables of interest were indicators of hepatic steatosis, liver enzymes, insulin resistance, inflammation and oxidative stress. | 29035092 |
| Primary malignant neoplasm, Catheter-Related Inflammation | Altered Intercellular Communication | C-C motif chemokine ligand 18 (CCL18) was reported as a chemokine-mediated tumor-related inflammation that can be detected in serum and may correlate with cancer patients' prognosis. | 29036787 |
| Inflammation | Altered Intercellular Communication | These patients have elevated oxidative stress and chronic inflammation. | 29036910 |
| Muscle damage, Inflammation, Pain Distress Question | Altered Intercellular Communication | We analyzed postoperative serum makers for muscle damage and inflammation, postoperative surgical pain, and performance status. | 29037186 |
| Inflammation | Altered Intercellular Communication | The location of involvement in the upper third of SI is insufficient to differentiate between degeneration and inflammation. | 29037308 |
| Inflammation, Systemic Scleroderma | Altered Intercellular Communication | Pulmonary magnetic resonance imaging is similar to chest tomography in detecting inflammation in patients with systemic sclerosis. | 29037314 |
| Pelvic Inflammatory Disease | Altered Intercellular Communication | Abdominal and pelvic imaging showed uterine and adnexal inflammation, and pelvic examination confirmed a diagnosis of pelvic inflammatory disease. | 29037929 |
| Inflammation, "Alzheimers Disease", neuron death, Data types - Address | Altered Intercellular Communication | Amyloid-b peptide (Ab) initiates a cascade of pathological events, including activation of microglial cells, oxidative stress, and inflammation, leading to neuronal death and the typical pathological changes in Alzheimer's disease (AD). | 29038004 |
| Inflammation, Impaired cognition | Altered Intercellular Communication | These results demonstrate that FLDK alleviates cognitive decline and reduces Ab burden, microglial activation, oxidative stress, and inflammation responses. | 29038004 |
| Inflammation | Altered Intercellular Communication | Young African females are at an increased risk of HIV acquisition, and genital inflammation or the vaginal microbiome may contribute to this risk. | 29038128 |
| Inflammation | Altered Intercellular Communication | Unsupervised clustering of 16S rRNA gene sequences revealed three clusters (subtypes), one of which was strongly associated with genital inflammation. | 29038128 |
| Inflammation | Altered Intercellular Communication | In a multivariate model, the microbiome compositional subtype and hormonal contraception were significantly associated with genital inflammation. | 29038128 |
| Inflammation, Aerococcus, Gemella, Sneathia, Genus Fusobacterium | Altered Intercellular Communication | We identified 40 taxa significantly associated with inflammation, including those reported previously (Prevotella, Sneathia, Aerococcus, Fusobacterium, and Gemella) as well as several novel taxa (including increased frequencies of bacterial vaginosis-associated bacterium 1 [BVAB1], BVAB2, BVAB3, Prevotella amnii, Prevotella pallens, Parvimonas micra, Megasphaera, Gardnerella vaginalis, and Atopobium vaginae and decreased frequencies of Lactobacillus reuteri, Lactobacillus crispatus, Lactobacillus jensenii, and Lactobacillus iners). | 29038128 |
| Bacterial Vaginosis, Inflammation | Altered Intercellular Communication | Community functional profiling revealed three distinct vaginal microbiome subtypes, one of which was characterized by extreme genital inflammation and persistent bacterial vaginosis (BV); this subtype could be predicted with high specificity and sensitivity based on the Nugent score (>=9) or BVAB1 abundance. | 29038128 |
| Acute and chronic inflammation, HIV Infections | Altered Intercellular Communication | We propose that women with this BVAB1-dominated subtype may have chronic genital inflammation due to persistent BV, which may place them at a particularly high risk for HIV infection. | 29038128 |
| Inflammation | Altered Intercellular Communication | In a multivariate model, the microbiome compositional subtype and hormonal contraception were significantly associated with genital inflammation. | 29038128 |
| Inflammation | Altered Intercellular Communication | As low-grade inflammation and increased plasma ferritin concentration are associated with all-cause mortality, we hypothesized that increased plasma ferritin concentration is genetically associated with low-grade inflammation. | 29038157 |
| Inflammation, Familial Mediterranean Fever, Autosomal recessive inheritance, Brucellosis | Altered Intercellular Communication | Familial Mediterranean fever (FMF) is an autosomal recessive disease characterized by recurrent episodes of painful inflammation in the abdomen, chest, or joints. | 29038396 |
| Inflammation, Anomia, Impaired cognition, "Alzheimers Disease | Altered Intercellular Communication | Systemic Inflammation and Multimodal Biomarkers in Amnestic Mild Cognitive Impairment and Alzheimer's Disease. | 29039020 |
| Inflammation, Data types - Address | Altered Intercellular Communication | However, the role of systemic inflammation in AD pathophysiology is much less understood. | 29039020 |
| Inflammation, Hippocampal atrophy, Data types - Address | Altered Intercellular Communication | Our findings indicate a possible relationship between systemic inflammation with DMN FC disruption, hippocampal atrophy, and CSF protein levels in the subjects with mild AD and aMCI. | 29039020 |
| Inflammation, Primary malignant neoplasm | Altered Intercellular Communication | Formyl peptide receptor 2 (FPR2) has been identified as a member of the G protein-coupled chemoattractant receptor (GPCR) family and has been implicated as playing a role in both inflammation and cancer development. | 29039544 |
| Communicable Diseases, ovarian neoplasm, Inflammation | Altered Intercellular Communication | Epithelial ovarian cancer (EOC) has been suggested to be correlated with both infectious and non-infectious inflammation. | 29039544 |
| Inflammation, Metabolic Syndrome X, Obesity | Altered Intercellular Communication | Central obesity is associated with chronic low-grade inflammation, and is a risk factor for cardiometabolic syndrome. | 29039967 |
| Inflammation, Thrombosis, Moist | Altered Intercellular Communication | Platelets express high-mobility group box 1 (HMGB1), a damage-associated molecular pattern molecule (DAMP) that triggers thrombosis and inflammation when present in extracellular space. | 29041001 |
| Refractory anemias, Inflammation, Rheumatoid Arthritis | Altered Intercellular Communication | The precise mechanism linking systemic inflammation with insulin resistance (IR) in rheumatoid arthritis (RA) remains elusive. | 29041949 |
| Islet Cell Tumor | Altered Intercellular Communication | Various inflammation-based prognostic scores have been associated with reduced survival in patients with nonfunctional pancreatic neuroendocrine tumor (NF-PNET). | 29042631 |
| Inflammation, Rheumatoid Arthritis | Altered Intercellular Communication | Identification of such modified proteins in inflamed gingiva may explain, in part, how inflammation of the periodontal tissues may influence the development of rheumatoid arthritis. | 29044530 |
"
| Inflammation, Blood Glucose | Altered Intercellular Communication | However, we found
significant between-group differences in other markers of insulin resistance (HbA1c, glycemia,
HOMA-IR) and inflammation. | 29045090 | "
| Hypotensive, Inflammation, Glaucoma, CTCAE | Altered Intercellular Communication | Chronic use of topical hypotensive therapies in glaucoma patients leads to chronic inflammation of the ocular surface, which decreases the success rate of long-term glaucoma management. | 29045169 |
| Glaucoma, Primary Open Angle, Inflammatory abnormality of the eye | Altered Intercellular Communication | Our data suggests that topical PEA (Defluxa) is a safe, effective, and generally well-tolerated treatment to prevent or suppress ocular surface inflammation attributable to chronic glaucoma treatment. | 29045169 |
| Colitis, Gastrointestinal inflammation, Pseudo-obstruction of gastrointestinal tract | Altered Intercellular Communication | Four distinct categories of GI-irAE were observed: acute colitis (n = 8, 40%), microscopic colitis (n = 7, 35%), upper gastrointestinal tract inflammation (n = 4, 20%) and pseudo-obstruction (n = 1, 5%). | 29045560 |
| Gastrointestinal inflammation, Colitis | Altered Intercellular Communication | Response rates to corticosteroids were 87.5% (7/8) in acute colitis, 57% (4/7) in microscopic colitis and 75% (3/4) in upper gastrointestinal tract inflammation. | 29045560 |
| Inflammation, Myocardial, Heart failure | Altered Intercellular Communication | Antibodies to receptors are associated with biomarkers of inflammation and myocardial damage in heart failure. | 29046223 |
| Inflammation, Tissue injury, Heart failure | Altered Intercellular Communication | Naturally occurring antibodies are linked to inflammation, tissue injury and apoptosis, processes also linked to heart failure. | 29046223 |
| Inflammation, Myocardial, Heart failure | Altered Intercellular Communication | Associations between antibodies, inflammation and myocardial damage, have not been elucidated in heart failure. | 29046223 |
| Inflammation, Heart failure | Altered Intercellular Communication | We investigated if 25 antibodies to receptors expressed in the cardiovascular system were associated with troponin-T, biomarkers of inflammation and clinical measures of disease severity, in patients with heart failure. | 29046223 |
| Inflammation, Myocardial, Heart failure | Altered Intercellular Communication | Antibodies to receptors are correlated and are associated with biomarkers of inflammation and myocardial damage, which further modifies their association with disease severity in heart failure. | 29046223 |
| Inflammation | Altered Intercellular Communication | Free circulating active elastase contributes to chronic inflammation in patients on hemodialysis. | 29046295 |
| Inflammation, Blood Vessel | Altered Intercellular Communication | This study tested the hypothesis that in states of noninfectious inflammation, elastase is released by PMNLs and acts in an uncontrolled manner to inflict vascular damage. | 29046295 |
| Inflammation, Diabetic Angiopathies | Altered Intercellular Communication | In addition, it suggests that free circulating elastase can serve as a new biomarker and therapeutic target to reduce inflammation and vascular complications in patients on hemodialysis. | 29046295 |
| Inflammation | Altered Intercellular Communication | Biological aging is associated with immune activation (IA) and declining immunity due to systemic inflammation. | 29046481 |
| Inflammation, Lung diseases | Altered Intercellular Communication | Such vascular remodeling can be associated with inflammation, shear stress, and hypoxia-conditions commonly seen in patients with lung diseases. | 29047102 |
| Inflammation, Pleural Effusion, Malignant, Carcinogenesis, Fibrosis Assessment, Pleural Effusion, CTCAE | Altered Intercellular Communication | Highly expressed proteins in malignant pleural effusion were associated with carcinogenesis and cell growth, and proteins associated with tuberculous pleural effusion played a role in the response to inflammation and fibrosis. | 29047238 |
| methyldopa, Inflammation | Altered Intercellular Communication | While inflammation seems to be continuously stimulated by RPE associated with late exudative AMD, this appears not to be the case with regard to angioregulatory mechanisms. | 29050001 |
| Chronic lymphocytic inflammation, Pontine structure, Clippers | Altered Intercellular Communication | Diagnostic criteria for chronic lymphocytic inflammation with pontine perivascular enhancement responsive to steroids (CLIPPERS). | 29050399 |
| Chronic lymphocytic inflammation, Pontine structure, Clippers | Altered Intercellular Communication | Chronic lymphocytic inflammation with pontine perivascular enhancement responsive to steroids (CLIPPERS) is a central nervous system inflammatory syndrome predominantly affecting the brainstem, cerebellum, and spinal cord. | 29050399 |
| Inflammation, Cardiac fibrosis, Eating, Obesity | Altered Intercellular Communication | Inflammation and obesity are associated with cardiac fibrosis, but the relationship between cardiac fibrosis and EAT is unknown. | 29050981 |
| Necrotizing granulomatous inflammation, Orbital Cellulitis | Altered Intercellular Communication | A rare case of orbital granulomatous inflammation from explosive hydraulic oil masquerading as orbital cellulitis. | 29053030 |
| Acute inflammation of orbit | Altered Intercellular Communication | The differential diagnosis for acute orbital inflammation is broad. | 29053030 |
| Necrotizing granulomatous inflammation, Orbital Cellulitis | Altered Intercellular Communication | We report a case of granulomatous orbital inflammation due to high-pressure oil injury to the orbit presenting as an atypical orbital cellulitis. | 29053030 |
| Orbital Pseudotumor | Altered Intercellular Communication | Here we review the presentation and treatment of orbital inflammation from oil. | 29053030 |
| Cystic Lesion, Inflammation, Odontogenic Tumors, Bone Diseases, Odontogenic Cysts | Altered Intercellular Communication | The histological diagnosis were grouped into the categories Cystic lesions of odontogenic origin, Periapical inflammation, Odontogenic tumors, Bone diseases, Health tissue and Nonspecific diagnostic. | 29053654 |
| Cystic Lesion, Inflammation, Odontogenic Cysts, Pathology | Altered Intercellular Communication | More than half of pathologies were cystic lesions of odontogenic origin (822/51.4%), followed by periapical inflammation (282/17.6%). | 29053654 |
| Inflammation, square decimeter, Obesity, Diabetes Mellitus | Altered Intercellular Communication | Obesity and diabetes mellitus type 2 (DM2) are characterized by chronic inflammation and oxidative stress [Donath et al. | 29053995 |
| Inflammation | Altered Intercellular Communication | An increase in glutathione peroxidase, a decrease in uric acid and no change in glutathione reductase, total antioxidant status, oxidative damage, inflammation and glucose markers were found. | 29053995 |
| Inflammation, Primary malignant neoplasm | Altered Intercellular Communication | The enzyme indoleamine 2,3-dioxygenase (IDO) is emerging as a facilitator of cancer development through its effects on cancer-associated inflammation. | 29054599 |
| Cessation of life, Mortality, Premature, Chronic disease | Altered Intercellular Communication | The main idea is that there is a common pathway from wellbeing and health to chronic disease ("chronopathy") and even to death, which comprises following steps: 1) unhealthy diet, sedentary life style and permanent exposition to xenobiotics and all kinds of noxious stimuli;-2) intestinal dysbiosis;-3) alteration of the intestinal mucus layer (especially that of the colon);-4) disruption of the endothelial tight junctions;-5) metabolic endotoxemia+bacterial translocation;-6) inflammation;-7) exacerbation of the enteric nervous system (ENS) and consequent maladaptation and malfunctioning of the colon;-8) epigenetic manifestations;-9) "chronopathy" and premature death. | 29055387 |
| Chronic lymphocytic inflammation, Pontine structure, Clippers | Altered Intercellular Communication | Chronic lymphocytic inflammation with pontine perivascular enhancement responsive to steroids (CLIPPERS): A pediatric case report with six year follow-up. | 29055484 |
| Chronic lymphocytic inflammation, Pontine structure, Clippers, Inflammatory disorder | Altered Intercellular Communication | Chronic lymphocytic inflammation with pontine perivascular enhancement responsive to steroids (CLIPPERS) is an inflammatory disorder involving brainstem, pons in particular, characterized by a predominant T-cell pathology and responsiveness to glucocorticosteroids. | 29055484 |
| Inflammation, mecarzole | Altered Intercellular Communication | Items of a GA and biomarkers of inflammation and nutrition may have prognostic significance in patients with MBC. | 29055624 |
| Psoriasis | Altered Intercellular Communication | Visceral Adiposity in Psoriasis is Associated With Vascular Inflammation by 18F-Fluorodeoxyglucose Positron-Emission Tomography/Computed Tomography Beyond Cardiometabolic Disease Risk Factors in an Observational Cohort Study. | 29055628 |
| vascular inflammations, Psoriasis | Altered Intercellular Communication | The authors sought to examine the relationship between visceral adipose tissue (VAT) and vascular inflammation (VI) by 18F-Fluorodeoxyglucose (18F-FDG) positron-emission tomography (PET)/computed tomography (CT) in psoriasis (PSO). | 29055628 |
| Steatohepatitis, Fibrosis Assessment, Non-alcoholic Fatty Liver Disease, Inflammation | Altered Intercellular Communication | Bariatric surgery in eligible morbidly obese individuals may improve liver steatosis, inflammation, and fibrosis; however, population-based data on the clinical benefits of bariatric surgery in patients with nonalcoholic fatty liver disease (NAFLD) are lacking. | 29055669 |
| Inflammation, Non-Small Cell Lung Carcinoma | Altered Intercellular Communication | The prognostic value of inflammation indexes in non small cell lung cancer (NSCLC) was not established. | 29057536 |
| Small cell carcinoma of lung | Altered Intercellular Communication | Our results demonstrated that F-NLR, a novel inflammation-based grading system, as well as the GPS, appeared to have value as a promising clinical predictor of the prognosis for the resectable non small cell lung cancer patients. | 29057536 |
| Inflammation, Hypopigmentation disorder | Altered Intercellular Communication | Acquired skin hypopigmentation has many etiologies, including autoimmune melanocyte destruction, skin aging, inflammation, and chemical exposure. | 29057565 |
| Inflammation, Renal function, Chronic Kidney Diseases | Altered Intercellular Communication | The markers of inflammation, monocyte activation, and impaired kidney function were also increased in those with CKD. | 29058166 |
| Abducens Nerve Diseases, Postoperative Hemorrhage, Inflammation, Ischemic peripheral neuropathy | Altered Intercellular Communication | Our two cases of Abducens palsy following reoperative orbital decompression may be due to ischemic neuropathy caused by postoperative hemorrhage or inflammation. | 29058517 |
| Inflammation | Altered Intercellular Communication | The two scales are coupled because the immune response causes inflammation and adaptation, which affects the biomechanical parameters of the tissue such as his elasticity. | 29060459 |
| Inflammation | Altered Intercellular Communication | During repeated inflammation and breathing cycles, the tissue weakens and breaks down. | 29060459 |
| Delirium, Inflammation | Altered Intercellular Communication | We used C-reactive protein (CRP) as a pathophysiologic marker of inflammation, previously associated with delirium. | 29061098 |
| Inflammation, Lung, Tuberculosis | Altered Intercellular Communication | Chronic inflammation, possibly exacerbated by cigarette smoking, is considered to be the primary cause of pulmonary damage in patients with tuberculosis (TB). | 29062328 |
| Pseudomyxoma Peritonei, Neoplasms | Altered Intercellular Communication | The neutrophil-lymphocyte ratio (NLR) and other inflammation-based scores have been used as a prognostic tool to predict survival in solid tumours including pseudomyxoma peritonei (PMP). | 29063804 |
| Inflammation, Squamous cell carcinoma | Altered Intercellular Communication | High-risk squamous cell carcinoma masquerading as dense inflammation on Mohs frozen sections. | 29064089 |
| Inflammation | Altered Intercellular Communication | This case report describes how high-risk SCC may masquerade as only a dense inflammation on frozen sections. | 29064089 |
| Inflammation, Cerebral Hemorrhage | Altered Intercellular Communication | Assessing Inflammation in Acute Intracerebral Hemorrhage with PK11195 PET and Dynamic Contrast-Enhanced MRI. | 29064155 |
| Inflammation, Neoplasm Metastasis, COL4A2 wt Allele, Cerebral Hemorrhage | Altered Intercellular Communication | Studies in animal models suggest that inflammation is a major contributor to secondary injury after intracerebral hemorrhage (ICH). | 29064155 |
| Inflammation, COL4A2 wt Allele | Altered Intercellular Communication | Direct, noninvasive monitoring of inflammation in the human brain after ICH will facilitate early-phase development of anti-inflammatory treatments. | 29064155 |
| Inflammation, Heart failure | Altered Intercellular Communication | Previous studies have indicated a correlation between heart failure, inflammation and poorer outcome. | 29064269 |
| Inflammation, Acute heart failure, F8 wt Allele | Altered Intercellular Communication | However, the pathogenesis and role of inflammation in acute heart failure (AHF) is incompletely studied and understood. | 29064269 |
| Inflammation | Altered Intercellular Communication | Elevated leukocyte count as a harbinger of systemic inflammation, disease progression, and poor prognosis: a review. | 29064542 |
| Communicable Diseases, Inflammation, Traumatic injury | Altered Intercellular Communication | Total leukocyte count increases significantly in response to infection, trauma, inflammation, and certain diseases. | 29064542 |
| Inflammation | Altered Intercellular Communication | Recent findings suggest that elevated leukocyte count within the normal range, but especially neutrophil and monocyte counts, may be a harbinger of increased systemic inflammation and subclinical disease. | 29064542 |
| Inflammation | Altered Intercellular Communication | This review summarises the most important findings on the links between leukocyte count, chronic systemic inflammation, and health outcomes in older adults. | 29064542 |
| Inflammation, Bipolar Disorder | Altered Intercellular Communication | Differences in the association of inflammation and tryptophan with depressive symptoms between white and non-white chronic dialysis patients. | 29065338 |
| Amyotrophic Lateral Sclerosis, Neurodegenerative Disorders, Inflammation | Altered Intercellular Communication | Amyotrophic lateral sclerosis (ALS) is a fatal neurodegenerative motor neuron disease accompanied by both systemic and central nervous system-specific inflammation as well as deregulated energy metabolism. | 29065369 |
| Presenile dementia, "Alzheimers Disease", Brain Diseases, Data types - Address | Altered Intercellular Communication | Alzheimer's disease (AD) is a progressive, neurodegenerative brain disorder that attacks neurotransmitters, brain cells, and nerves, affecting brain functions, memory, and behaviors and then finally causing dementia on elderly people. | 29065619 |
| Inflammation, Rheumatoid Arthritis | Altered Intercellular Communication | Changes in clinical disease activity are weakly linked to changes in MRI inflammation on treat-to-target escalation of therapy in rheumatoid arthritis. | 29065903 |
| Inflammation | Altered Intercellular Communication | We compared changes in the DAS28CRP with changes in magnetic resonance imaging (MRI) inflammation on treatment escalation. | 29065903 |
| Inflammation | Altered Intercellular Communication | Scan pairs were scored for inflammation (MRI(i)) and damage. | 29065903 |
| Refractory anemias, Inflammation | Altered Intercellular Communication | We report the first study investigating the link between changes in clinical and imaging inflammation in a real-world RA cohort escalating to conventional and biologic DMARDs. | 29065903 |
| Intestinal dysbiosis, Gastrointestinal inflammation | Altered Intercellular Communication | Severe intestinal dysbiosis is a prevalent finding in pSS and is associated both with clinical and laboratory markers of systemic disease activity as well as gastrointestinal inflammation. | 29065905 |
| Inflammation, Hereditary, Arthropathy | Altered Intercellular Communication | Ultrasound verified inflammation and structural damage in patients with hereditary haemochromatosis-related arthropathy. | 29065925 |
| palladium, Inflammation | Altered Intercellular Communication | Inflammation was also common in HH-WA, yielding GSS in 83.3% and PD signals in 50.0% of patients. | 29065925 |
| Inflammation, Cartilage damage | Altered Intercellular Communication | A high prevalence of ultrasound-verified inflammation and cartilage damage was found in HH-A, and to a lesser extent in HH-WA. | 29065925 |
| Inflammation, Keratoconus | Altered Intercellular Communication | Langerhans cells were present in a significant number of subjects suggesting the possibility of inflammation in keratoconus. | 29066264 |
| Inflammation, Keratoconus | Altered Intercellular Communication | Based on the association of Langerhans cells with nerve parameters, we propose inflammation as the underlying cause for corneal nerve changes in keratoconus. | 29066264 |
| Airway structure, Asthma | Altered Intercellular Communication | We report the utility of combining lung sound analysis and fractional exhaled nitric oxide (FeNO) for phenotype classification of airway inflammation in patients with bronchial asthma. | 29066290 |
| Inflammation, Atherosclerosis | Altered Intercellular Communication | Inflammation plays a key role in atherosclerosis, but the association between inflammatory biomarkers and clinical outcomes is less studied in this population. | 29066452 |
| Inflammation | Altered Intercellular Communication | Up-regulated expression of GPR109A may be an inflammatory consequence and the improvement of inflammation may down-regulate the expression of GPR109A in T2DM. | 29066482 |
| Inflammation, Amyloidosis | Altered Intercellular Communication | Intramyocardial inflammation predicts adverse outcome in patients with cardiac AL amyloidosis. | 29067795 |
| Inflammation, Amyloidosis | Altered Intercellular Communication | Patients suffering from amyloidosis revealed a significant poor prognosis with proof of intramyocardial inflammation in contrast to those without inflammation (log-rank P = 0.019). | 29067795 |
| Inflammation, Amyloidosis, Myocarditis | Altered Intercellular Communication | The detailed subgroup analysis showed that patients suffering from AL amyloidosis with intramyocardial inflammation have a significantly worse prognosis compared with AL amyloidosis without inflammation and ATTR with or without inflammation, respectively (log-rank P = 0.014, contingency Fisher's exact test, P = 0.008). | 29067795 |
| Senile cardiac amyloidosis, Inflammation, Amyloidosis, Myocarditis | Altered Intercellular Communication | Our study reports for the first time a high incidence (48.1%) of intramyocardial inflammation in a series of patients with EMB-proven cardiac amyloidosis and could show that in patients with AL amyloidosis, intramyocardial inflammation correlated significantly with increased mortality. | 29067795 |
| Amyloidosis, Myocarditis | Altered Intercellular Communication | Our data have a direct clinical impact because one can hypothesize that additional immunomodulating/anti-inflammatory treatment regimens in patients with biopsy-proven inflammation of heart muscle tissue could be beneficial for patients suffering from cardiac AL amyloidosis. | 29067795 |
| Hormone abnormality, Hyperparathyroidism, Chronic Kidney Diseases, HYPERPARATHYROIDISM, NEONATAL SEVERE | Altered Intercellular Communication | INTRODUCTION Secondary hyperparathyroidism (SHPT) is a common hormonal disorder associated with chronic kidney disease (CKD). | 29067991 |
| Inflammation, Asthma | Altered Intercellular Communication | Sputum TWEAK level also showed significant positive correlations with asthma severity (r = .358, P = .001) and control status (r = .470, P < .001), distinctively in subjects with NEA inflammation. | 29068159 |
| Airway structure | Altered Intercellular Communication | Airway TWEAK may play a role in small airway inflammation especially in children with non-eosinophilic asthma. | 29068159 |
| Inflammation, Hemorrhage, Necrosis | Altered Intercellular Communication | Histological examination of the vascular bundle showed an electrocautery injury of the arterial wall: transmural necrosis, acute inflammation, and hemorrhage. | 29068812 |
| Inflammation, Congenital heart disease | Altered Intercellular Communication | Infants with congenital heart disease frequently require cardiopulmonary bypass, which causes systemic inflammation. | 29068910 |
| Bursitis | Altered Intercellular Communication | Pes anserine (PA) bursitis is an inflammatory condition of the medial knee. | 29069005 |
| Inflammation, Cartilage destruction, polychondritis, Multiple System Atrophy, Retinitis Pigmentosa | Altered Intercellular Communication | Relapsing polychondritis (RP) is a multisystemic, progressive disease of unknown etiology characterized by recurrent inflammation and progressive cartilage destruction. | 29069021 |
| Retinitis Pigmentosa, Inflammatory disorder of cartilage | Altered Intercellular Communication | Based on our patient presentation, we suggest that RP should be suspected in any transplant recipient with cartilage inflammation, and that the Michet's clinical criteria and scintigraphy seem to be the best diagnostic tools for solid organ transplant recipients suspected of RP. | 29069021 |
| Chorioretinitis, Inflammatory abnormality of the eye | Altered Intercellular Communication | Syphilitic chorioretinitis should be included in differential diagnosis of any form of ocular inflammation. | 29069031 |
| Inflammatory abnormality of the eye, Disorder of the optic nerve, Uveitis | Altered Intercellular Communication | It is necessary to reiterate the importance of including syphilis uveitis as a differential diagnosis for any form of ocular inflammations, especially posterior uveitis and optic neuropathy. | 29069031 |
| ARCN1 gene, Communicable Diseases, Chlamydia, Inflammation | Altered Intercellular Communication | The association between serological features of chronic Chlamydia pneumoniae infection and markers of systemic inflammation and nutrition in COPD patients. | 29069917 |
| ARCN1 gene, Communicable Diseases, Inflammation, physiopathological | Altered Intercellular Communication | The aim of the study was to investigate the association between chronic C. pneumoniae infection and clinical features of COPD, markers of inflammation and metabolic dysfunction. | 29069917 |
| Hemorrhagic, Inflammation, Central retinal vessel vascular tortuosity, Aneurysm, Ruptured | Altered Intercellular Communication | These hemorrhagic lesions, for example, a ruptured pseudoaneurysm, are often treated by transarterial embolization (TAE), but prior intervention or surgery, inflammation, anatomic variants, and vessel tortuosity may render an endovascular approach challenging, time-consuming, and sometimes impossible. | 29070606 |
| Inflammation, Aortic Stiffness, Obesity, Diabetes Mellitus | Altered Intercellular Communication | The prevalence of blunted nocturnal BP dipping is higher in persons with obesity and diabetes, conditions that are also associated with elevated aortic stiffness and inflammation. | 29070829 |
| Inflammation, Aortic Stiffness, Obesity, Blood Glucose | Altered Intercellular Communication | Therefore, we hypothesized that elevated glycemia, inflammation and aortic stiffness would be inversely associated with the magnitude of nocturnal systolic BP dipping among middle-aged/older adults with obesity at high CVD risk. | 29070829 |
| Inflammation, Aortic Stiffness, Obesity | Altered Intercellular Communication | Twenty-four hour ambulatory BP monitoring, aortic stiffness (carotid-femoral pulse wave velocity, CF-PWV), hemoglobin A1c (HbA1c) and inflammation (C-reactive protein, CRP) were measured in 86 middle-aged/older adults with obesity and at least one other CVD risk factor (age 40-74 years; 34 male/52 female; body mass index=36.7+-0.5 kg m-2; HbA1c=5.7+-0.04%). | 29070829 |
| Inflammation | Altered Intercellular Communication | These data suggest that impaired long-term glycemic control and higher inflammation may contribute partly to blunted BP dipping in middle-aged/older adults with obesity-related prediabetes. | 29070829 |
| Herpes Zoster Ophthalmicus, Inflammatory abnormality of the eye | Altered Intercellular Communication | To analyze and compare the clinical profile of herpes zoster ophthalmicus (HZO) patients in a South Indian patient population aged <60 years and >=60 years and determine the risk factors for recurrence of ocular inflammation. | 29072860 |
| Inflammation, Diabetes Mellitus | Altered Intercellular Communication | Presence of diabetes mellitus, increased intraocular pressure(IOP) at the time of active inflammation, use of topical steroids and recurrences were significantly more common in group 1. | 29072860 |
| Inflammation, Insulitis, Neoplasms | Altered Intercellular Communication | To explore the biological significance of Ninj1, we generated a cohort of Ninj1-deficient mice and found that Ninj1+/- mice were prone to systemic inflammation and insulitis, but not to spontaneous tumors. | 29073078 |
| Inflammation, Diabetes Mellitus, Non-Insulin-Dependent, Obesity, Cardiovascular Diseases | Altered Intercellular Communication | Obesity promotes excessive inflammation, which is associated with senescence-like changes in visceral adipose tissue (VAT) and the development of type 2 diabetes (T2DM) and cardiovascular diseases. | 29073165 |
| Inflammation, Graft-vs-Host Disease | Altered Intercellular Communication | There is experimental evidence that coexisting inflammation aggravates aGVHD. | 29074374 |
| Inflammatory Bowel Diseases, Inflammation | Altered Intercellular Communication | Mucosal inflammation must be carefully monitored to improve the long-term outcomes of patients with inflammatory bowel diseases (IBD). | 29074448 |
| Inflammatory Bowel Diseases, Crohn Disease, Ulcerative Colitis, Inflammatory disease of mucous membrane | Altered Intercellular Communication | Only 6 PROMs (patient-reported global assessment, patient assessment of disease activity, mobile health index for Crohn's disease, mobile health index for ulcerative colitis, patient-reported outcome derived from the Mayo score, and the 6-point Mayo score) were validated as markers of IBD activity, using findings from endoscopy as the reference standard; these PROMs identified patients with mucosal inflammation with area under the curve values of 0.63-0.82. | 29074448 |
| Inflammation | Altered Intercellular Communication | RV568, a narrow-spectrum kinase inhibitor with p38 MAPK-a and -g selectivity, suppresses COPD inflammation. | 29074542 |
| Inflammation, Malignant Neoplasms | Altered Intercellular Communication | Neutrophil-lymphocyte ratio (NLR) is a hematological marker of systemic inflammation and several studies demonstrate an association between a higher NLR and a worse prognosis in many malignancies. | 29076002 |
| Malignant Neoplasms | Altered Intercellular Communication | Exosomal miRNAs that play an important role in cell-cell communication have attracted major attention as potential diagnostic and prognostic biomarkers for various cancers. | 29076027 |
| Inflammation, Growth | Altered Intercellular Communication | Other less frequent findings were non-specific inflammation and fungating growths in rectum. | 29076685 |
| Inflammation, Tuberculosis | Altered Intercellular Communication | Result of biopsy showed granulomatous inflammation confirming pelvic tuberculosis. | 29076692 |
| Inflammation, Traumatic, Neoplasms, Communicable Diseases, Otosclerosis, Meniere Disease, Cerebrovascular Disorders, MS gene | Altered Intercellular Communication | Cases with inflammation in the middle or inner ear; a retro cochlear tumor; autoimmune, infectious, functional, metabolic, neoplastic, traumatic, toxic, or vascular causes; Meniere's disease; otosclerosis; multiple sclerosis; and/or cerebrovascular diseases were excluded. | 29076927 |
| Inflammation, Tuberculosis | Altered Intercellular Communication | However, when the CNV development is not accompanied by clear signs of inflammation, the etiology can be missed, especially in countries nonendemic for tuberculosis. | 29077184 |
| Inflammatory Bowel Diseases, Inflammation | Altered Intercellular Communication | Epstein-Barr virus (EBV) has been associated with inflammation in the colon, particularly in patients with inflammatory bowel disease (IBD). | 29078077 |
| Colitis | Altered Intercellular Communication | Further studies are necessary to confirm this association and to clarify the role of EBV in MC and, more generally, in colonic inflammation. | 29078077 |
| Inflammation, Lung diseases | Altered Intercellular Communication | Exhaled breath condensate (EBC) has emerged as a noninvasive method for assessing inflammation in lung diseases. | 29078843 |
| ARCN1 gene, Inflammation | Altered Intercellular Communication | TNF-a and IL-1b in EBC are potential biomarkers for evaluating pulmonary function and inflammation in patients with COPD. | 29078843 |
| ARCN1 gene, Inflammation | Altered Intercellular Communication | Furthermore, lung-protective treatment is effective in reducing inflammation in patients with COPD. | 29078843 |
| Inflammation | Altered Intercellular Communication | The pleiotropic pro-inflammatory cytokine, macrophage migration inhibitory factor (MIF), represents an important link between chronic inflammation and tumorigenesis. | 29079416 |
| Inflammation, Scleroderma | Altered Intercellular Communication | Before commencing tocilizumab, there was evidence of significant systemic inflammation, and progressive sclerodermatous changes (physician global assessment [PGA] 7/10). | 29079714 |
| Obesity, prostatitis | Altered Intercellular Communication | Molecular correlates in urine for the obesity and prostatic inflammation of BPH/LUTS patients. | 29080225 |
| Obesity, Benign prostatic hypertrophy, prostatitis | Altered Intercellular Communication | Benign prostatic hyperplasia (BPH) is strongly associated with obesity and prostatic tissue inflammation, but the molecular underpinning of this relationship is not known. | 29080225 |
| Lower Urinary Tract Symptoms, Obesity, prostatitis | Altered Intercellular Communication | Here, we examined the association between urine levels of chemokines/adipokines with histological markers of prostate inflammation, obesity, and lower urinary tract symptoms LUTS in BPH patients. | 29080225 |
| Inflammation, prostatitis | Altered Intercellular Communication | CCL3 in 15 patients with moderate to severe grade inflammation was marginally associated with maximal CD20 infiltration (P = 0.09), whereas CCL3 was undetectable in men with mild prostate tissue inflammation. | 29080225 |
| Lymphocytic infiltration, prostatitis | Altered Intercellular Communication | Increased urine levels of CXCL-10, CCL5, and CCL3 were marginally associated with the scores for prostate tissue inflammation and lymphocytic infiltration. | 29080225 |
| Metabolic Diseases, prostatitis | Altered Intercellular Communication | Overall, elevated urinary chemokines support that BPH is a metabolic disorder and suggest a molecular link between BPH/LUTS and prostatic inflammation. | 29080225 |
| Inflammation, Muscle, Smooth, Vascular, In-Stent Restenosis Indicator | Altered Intercellular Communication | Increased serum TREM-1 level is associated with in-stent restenosis, and activation of TREM-1 promotes inflammation, proliferation and migration in vascular smooth muscle cells. | 29080545 |
| Inflammation | Altered Intercellular Communication | These data suggest that TREM-1 is a predictive biomarker of ISR and an important mediator of cellular inflammation, migration, and proliferation in VSMCs. | 29080545 |
| Non-insulin Hypoglycemic, Inflammation, Infection caused by Helicobacter pylori, Diabetes Mellitus, Non-Insulin-Dependent | Altered Intercellular Communication | Male non-insulin users with type 2 diabetes mellitus are predisposed to gastric corpus-predominant inflammation after H. pylori infection. | 29082856 |
| precancerous lesions, Gastritis, Diabetes Mellitus, Non-Insulin-Dependent, Infection caused by Helicobacter pylori | Altered Intercellular Communication | This study investigated whether patients with type 2 diabetes mellitus (T2DM) and H. pylori infection had more severe corpus gastric inflammation and higher prevalence of precancerous lesions than non-diabetic controls. | 29082856 |
| Gastritis, Diabetes Mellitus, Non-Insulin-Dependent, Infection caused by Helicobacter pylori | Altered Intercellular Communication | Patients with type 2 diabetes mellitus and H. pylori infection had more severe corpus gastric inflammation than non-diabetic controls. | 29082856 |
| Chronic disease | Altered Intercellular Communication | Inflammatory conditions in the joint hamper the application of tissue engineering during chronic joint diseases. | 29083361 |
| Pneumonitis, CTCAE, Inflammation, Toxic effect, Cessation of life | Altered Intercellular Communication | Pneumonitis is defined as a focal or diffuse inflammation of the lung parenchyma, and is a known, potentially fatal toxicity of anti-programmed death 1 (PD-1)/programmed death ligand 1 (PD-L1) immune checkpoint inhibitors. | 29083466 |
| Inflammation, Photoreceptors | Altered Intercellular Communication | Cytokine stimulation of Muller glia resulted in production of NTs, and GDNF treatment reduced photoreceptor cell death in response to inflammation and oxidative stress. | 29084332 |
| Inflammation, Hypertension, CTCAE, Endothelial dysfunction | Altered Intercellular Communication | Inflammation and endothelial dysfunction may play an important role in the multifactorial pathogenesis of hypertension. | 29084442 |
| Inflammation, Stress Disorders, Traumatic | Altered Intercellular Communication | The Role of Inflammation in Late-Life Post-Traumatic Stress Disorder. | 29087846 |
| Post-Traumatic Stress Disorder, Inflammation | Altered Intercellular Communication | There is evidence that immune system dysregulation and inflammation may play a role in the development of post-traumatic stress disorder (PTSD). | 29087846 |
| Post-Traumatic Stress Disorder, Inflammation | Altered Intercellular Communication | However, it is unclear whether exacerbation of PTSD symptoms late in life is also associated with elevated inflammation. | 29087846 |
| Post-Traumatic Stress Disorder, Inflammation | Altered Intercellular Communication | The purpose of this pilot study was to examine the relationship between inflammation and late-life PTSD. | 29087846 |
| Post-Traumatic Stress Disorder, Inflammation | Altered Intercellular Communication | The results from this pilot study suggest that late-life PTSD may be associated with increased inflammation. | 29087846 |
| Post-Traumatic Stress Disorder, Inflammation | Altered Intercellular Communication | Further research in larger samples is needed to corroborate these findings and to clarify the relationship between inflammation and PTSD, which may lead to improved methods of diagnosis and treatment. | 29087846 |
| Non-Small Cell Lung Carcinoma | Altered Intercellular Communication | Systemic immune-inflammation index predicting chemoradiation resistance and poor outcome in patients with stage III non-small cell lung cancer. | 29089030 |
| Inflammation, Neoplasms | Altered Intercellular Communication | There is increasing evidence that the existence of systemic inflammation response is correlated with poor prognosis in several solid tumors. | 29089030 |
| Intrahepatic Cholangiocarcinoma, Cholangitis, Malignant Neoplasms | Altered Intercellular Communication | Intrahepatic cholangiocarcinoma (iCCA) represents a heterogeneous group of malignancies emerging from the biliary tree, often in the context of chronic bile ducts inflammation. | 29089545 |
| ARCN1 gene, Inflammation, Anemia, Diabetes Mellitus | Altered Intercellular Communication | Presence of COPD was associated with predominance of diabetes mellitus, interleukin-8-related systemic neutrophilic inflammation and anemia. | 29089753 |
| Inflammation, Fibrosis Assessment | Altered Intercellular Communication | The pathologic features of post-ischemic stricture were deep ulceration, submucosal/subserosal fibrosis and chronic transmural inflammation. | 29089826 |
| Inflammation, Secondary malignant neoplasm of skin, Congenital Abnormality, Refractory anemias, Rheumatoid Arthritis | Altered Intercellular Communication | Foot symptoms in rheumatoid arthritis (RA) derive from a combination of inflammation, altered foot mechanics, deformity and secondary skin lesions. | 29090022 |
| Inflammation, acute diverticulitis | Altered Intercellular Communication | Serum inflammation markers may help to differentiate severity of acute diverticulitis and predict the need for surgical intervention in clinical practice. | 29091955 |
| Pituitary microadenoma, Parathyroid Adenoma | Altered Intercellular Communication | Screening of other endocrine glands revealed pituitary microadenoma and parathyroid adenoma on imaging, which was also supported by biochemical and hormonal profile. | 29092962 |
| Inflammation | Altered Intercellular Communication | A regime of three boluses leads to a smaller decrease in the level of Hb, less post-operative inflammation and a shorter length of stay in hospital than a single bolus. | 29092982 |
| RANGAP1 wt Allele, Inflammation, "Alzheimers Disease | Altered Intercellular Communication | Each SD increase in midlife inflammation composite score was associated with 1,788 mm3 greater ventricular (p = 0.013), 110 mm3 smaller hippocampal (p = 0.013), 519 mm3 smaller occipital (p = 0.009), and 532 mm3 smaller Alzheimer disease signature region (p = 0.008) volumes, and reduced episodic memory (p = 0.046) 24 years later. | 29093073 |
| Inflammation, Nerve Degeneration | Altered Intercellular Communication | Our prospective findings provide evidence for what may be an early contributory role of systemic inflammation in neurodegeneration and cognitive aging. | 29093073 |
| Inflammation, Liver damage | Altered Intercellular Communication | These findings suggest that reduced NFKBIA function leads to activation of the NF-kB pathway, and consequently causes inflammation and liver damage among patients with chronic HBV infection. | 29093318 |
| Granulomatous inflammation | Altered Intercellular Communication | Transbronchial lung biopsy revealed the presence of granulomatous inflammation. | 29093420 |
| Inflammation, Postoperative Period | Altered Intercellular Communication | A surgical approach was not indicated because a few days may have already passed since postoperative perforation occurred and the spread of inflammation to the retroperitoneum was suspected. | 29094323 |
| Inflammatory abnormality of the eye | Altered Intercellular Communication | To investigate a pixel densitometry index (PDI) for measuring ocular surface inflammation (OSI). | 29095066 |
| Inflammation | Altered Intercellular Communication | Autoantibody deposition in the skin causes inflammation and intraepidermal akantholysis. | 29096849 |
| Inflammation | Altered Intercellular Communication | Whole grain-rich diet reduces body weight and systemic low-grade inflammation without inducing major changes of the gut microbiome: a randomised cross-over trial. | 29097438 |
| Inflammation | Altered Intercellular Communication | Compared with refined grain diet, whole grain diet did not alter insulin sensitivity and gut microbiome but reduced body weight and systemic low-grade inflammation. | 29097438 |
| Kidney Failure, Chronic, Inflammation, Atherosclerosis | Altered Intercellular Communication | Chronic inflammation may contribute to atherosclerosis and cardiovascular (CVD) mortality in end-stage kidney disease (ESKD). | 29097485 |
| palladium, HD Term Type, Inflammation | Altered Intercellular Communication | To examine the effects of initiating HD and PD upon inflammation and CVD risk markers in ESKD patients. | 29097485 |
| Inflammation, Manufactured sign | Altered Intercellular Communication | Of the 53 resected appendixes, the histopathological evaluation showed 33 (62.2%) inconspicuous appendices, 11 (20.8%) post-inflammatory changes, 4 (7.5%) with chronical signs of inflammation and 3 (5.7%) with signs of acute inflammation. | 29098385 |
| Inflammation, Metabolic Diseases | Altered Intercellular Communication | A multifunctional diet (MFD) targeting subclinical inflammation was developed as a tool to decrease risk factors for cardiometabolic disease in healthy "at-risk" individuals (BMI 25-33 kg/m2). | 29098426 |
| Inflammation, Atherosclerosis | Altered Intercellular Communication | Inflammation plays a key role in the development of insulin resistance and atherosclerosis. | 29098425 |
| Inflammation | Altered Intercellular Communication | Our findings indicated that a single SFA-enriched meal is able to acutely induce the IL-1b expression and regularly consumed could trigger systemic inflammation, while increased unSFA consumption could attenuate the inflammatory status. | 29098425 |
| Inflammation, Neoplasms | Altered Intercellular Communication | The correlation of C-reactive protein decrease with significantly improved OS underlines the close link between inflammation and tumor control. | 29098441 |
| Inflammation | Altered Intercellular Communication | Bacterial load (total bacterial abundance) determined local parameters of ulcer inflammation. | 29098740 |
| Communicable Diseases, Inflammation, Systemic disease, Neoplasms | Altered Intercellular Communication | IgG4-RD could mimic conditions other than tumors, such as infection, inflammation, or other systemic disorders. | 29099539 |
| Inflammation, ETV3 wt Allele | Altered Intercellular Communication | Both MetS components and biomarkers of inflammation (IF) are predictive factors for LVDD. | 29099655 |
| Communicable Diseases, Inflammation, Tuberculosis, Pulmonary | Altered Intercellular Communication | Serum samples from 319 protocol-correct, culture-confirmed pulmonary tuberculosis patients treated under direct observation as part of an international, phase 2 trial were screened for 70 markers of infection, inflammation, and metabolism. | 29100778 |
| Atherosclerosis | Altered Intercellular Communication | Midlife Systemic Inflammation, Late-Life White Matter Integrity, and Cerebral Small Vessel Disease: The Atherosclerosis Risk in Communities Study. | 29101255 |
| Inflammation, Leukoaraiosis, One Vessel Coronary Disease | Altered Intercellular Communication | It is currently unclear whether midlife systemic inflammation promotes the development of white matter (WM) abnormalities and small vessel disease in the elderly. | 29101255 |
| Inflammation | Altered Intercellular Communication | Our findings support the hypothesis that midlife systemic inflammation may promote the development of chronic microangiopathic structural WM abnormalities in the elderly. | 29101255 |
| Airway structure, ARCN1 gene | Altered Intercellular Communication | A nested subcohort of 141 patients, followed for up to 6 months, was studied to test if MBL deficiency was associated with altered sputum microbiota, through 16S rRNA PCR and sequencing, or airway inflammation during stable and exacerbated COPD. | 29101284 |
| Airway structure | Altered Intercellular Communication | There were lower levels of airway inflammation in patients with MBL deficiency. | 29101284 |
| Human Placental Lactogen, muscle mass | Altered Intercellular Communication | Inflammation markers were associated with measures of muscle mass, strength and function in HCS. | 29101476 |
| Inflammation, Rheumatoid Arthritis | Altered Intercellular Communication | Red blood cell distribution width: a potential laboratory parameter for monitoring inflammation in rheumatoid arthritis. | 29101675 |
| Refractory anemias, Tumor necrosis, Rheumatoid Arthritis, Inflammation | Altered Intercellular Communication | Correlation analysis of red blood cell distribution width (RDW) and C-reactive protein (CRP), erythrocyte sedimentation rate (ESR), tumor necrosis factor a (TNF-a), interleukin (IL)-6, and IL-10 in rheumatoid arthritis (RA) to investigate whether RDW can serve as a potential parameter for indicating inflammation in RA patients. | 29101675 |
| Refractory anemias, Inflammation | Altered Intercellular Communication | RDW was increased in patients with RA which was associated with inflammation in RA, suggesting that RDW may be a potential auxiliary marker for indicating inflammation process in RA conveniently. | 29101675 |
| Inflammation, Calcinosis | Altered Intercellular Communication | Symptomatic lesions exhibited less calcification, with greater inflammation characterized by increased expression of CD68+ and CD163+ macrophage subsets, and Lp-PLA2. | 29101839 |
| Cessation of life, Inflammation, Atherosclerotic lesion, Necrosis | Altered Intercellular Communication | Statin treatment has no effect on local atherosclerotic lesion Lp-PLA2 activity, therefore, the addition of anti-inflammatory treatments to further decrease macrophage Lp-PLA2 expression in atherosclerotic lesions may reduce lesional inflammation and cell death, and prevent necrotic core expansion and lesion progression. | 29101839 |
| Pneumonitis | Altered Intercellular Communication | r-Der f 31 can induce allergic pulmonary inflammation in the mouse model. | 29102047 |
| Inflammation, Malnutrition | Altered Intercellular Communication | Low T3 and FT3 levels are correlated with malnutrition and inflammation parameters. | 29102271 |
| Amblyopia, Vitreous inflammatory cells | Altered Intercellular Communication | Vitreous inflammation gradually resolved with oral steroids, and amblyopia treatment with left eye patching was advised. | 29102673 |
| Crohn Disease, Inflammatory abnormality of the eye, Uveitis | Altered Intercellular Communication | This case of Crohn's disease and uveitis is unusual in that ocular inflammation preceded intestinal involvement, with the atypical feature of chronic intermediate uveitis. | 29102673 |
| Inflammation, Pulmonary Edema | Altered Intercellular Communication | Negative pressure ventilation decreases inflammation and lung edema during normothermic ex-vivo lung perfusion. | 29103845 |
| Inflammation, Lung Injury | Altered Intercellular Communication | Utilization of an NPV strategy during extended EVLP is associated with significantly less inflammation, and lung injury, irrespective of perfusate solution composition. | 29103845 |
| Communicable Diseases, Inflammation | Altered Intercellular Communication | The presence of human papilloma virus (HPV) infection and the occurrence of genital inflammation were documented. | 29104417 |
| Human papilloma virus infection, Inflammation, Vulval intraepithelial neoplasia | Altered Intercellular Communication | Smoking, HPV infection, genital inflammation, and complete pubic hair removal were significantly more common in the vulvar dysplasia/cancer group. | 29104417 |
| Inflammation, Vulval intraepithelial neoplasia, Malignant Neoplasms | Altered Intercellular Communication | Our findings suggest that partial or complete pubic hair shaving using a razor is correlated with and could be a potential risk factor for the development of genital inflammation, vulvar dysplasia, and malignancies. | 29104417 |
| Deficit | Altered Intercellular Communication | We hypothesized that these hormonal deficits lead to increased apoptosis of the epithelial cells and plasmacytoid dendritic cell (pDC)-mediated proinflammatory host responses. | 29105068 |
| Inflammation, Rheumatoid Arthritis | Altered Intercellular Communication | Acute effect of a resistance exercise session on markers of cartilage breakdown and inflammation in women with rheumatoid arthritis. | 29105312 |
| Refractory anemias, Inflammation, Rheumatoid Arthritis | Altered Intercellular Communication | To assess the acute effect of resistance exercise (RE) on circulating biomarkers of cartilage breakdown and inflammation in women with rheumatoid arthritis (RA). | 29105312 |
| Refractory anemias, Inflammation | Altered Intercellular Communication | Women with and without RA have similar changes in response to a RE session in levels of inflammation biomarkers, but not of cartilage breakdown. | 29105312 |
| Inflammation, physiopathological, Impaired | Altered Intercellular Communication | Angiotensin converting enzyme (ACE) inhibitors, angiotensin II receptor blockers (ARBs) were inversely associated with cardiac impairment, inflammation, and renal tubular damage, but not with glomerular dysfunction. | 29105751 |
| Pain Distress Question, Inflammation, Anxiety, CTCAE 3.0, Chronic pain | Altered Intercellular Communication | In the multivariate models, moderate to severe average pain in the 4 weeks after ICUDC , lower age, female sex, increased inflammation and chronic pain conditions and increased levels of anxiety before ICU admission were predictive for CIRP. | 29105897 |
| Portal Hypertension, Inflammation, CRNKL1 wt Allele | Altered Intercellular Communication | Circulating CXCL10 in cirrhotic portal hypertension might reflect systemic inflammation and predict ACLF and mortality. | 29105936 |
| Inflammation, Fibrosis Assessment, Injury of liver | Altered Intercellular Communication | CXCR% ligands play an important role in hepatic injury, inflammation and fibrosis. | 29105936 |
| Decompensation, Inflammation, Hypertension, CTCAE, CRNKL1 wt Allele | Altered Intercellular Communication | Circulating CXCL10 possibly reflects systemic inflammation and it is correlated with acute decompensation, ACLF and complications in patients with severe portal hypertension receiving TIPS. | 29105936 |
| Inflammation, SDSL gene | Altered Intercellular Communication | However, the association between the biomarkers of inflammation and angiogenesis, and the clinical and radiological characteristics of CSDH patients, need further investigation. | 29107999 |
| Inflammation, Bipolar Disorder | Altered Intercellular Communication | Recent evidence suggests a notable role for inflammation and immune dysregulation in the neuroprogression of bipolar disorders (BD). | 29108425 |
| Inflammation, Pathological Dilatation | Altered Intercellular Communication | Vascular pathology was mapped, and correlations were sought between the vascular findings and bowel distension, inflammation, neuromuscular anatomy, preoperative clinical variables, and postsurgical complications. | 29108502 |
| Inflammation, Necrosis | Altered Intercellular Communication | Adventitial inflammation and/or medial necrosis was present in the immature form (6/16). | 29108502 |
| Cryptitis, Acute inflammation | Altered Intercellular Communication | Confocal imaging focused on 2 highly reproducible histologic hallmarks of active colonic inflammation: focal cryptitis and crypt architectural abnormality. | 29108979 |
| Organ Dysfunction Scores, Malignant Neoplasms | Altered Intercellular Communication | We defined young adult cancers as those occurring between the ages of 20 and 39 years because these individuals will have passed puberty and adolescence, but not yet experienced the effects of hormonal decline, immune response deterioration, or organ dysfunction associated with chronic health conditions. | 29111259 |
| Inflammation | Altered Intercellular Communication | C-reactive protein concentration as a prognostic factor for inflammation in the management of odontogenic infections. | 29113735 |
| Inflammation, Hypertension, CTCAE | Altered Intercellular Communication | In particular, significant variants were mapped to genes known to be associated with inflammation, hypertension, lipid metabolism, height, and increased lifespan in mice. | 29113935 |
| Inflammation, Kidney Diseases | Altered Intercellular Communication | All 3 markers showed moderate correlations with markers of kidney and liver disease and inflammation (ie, systemic symptoms of RVCL-S). | 29114091 |
"
| Nonalcoholic Steatohepatitis, Hypogonadism, hormone deficiency | Altered Intercellular Communication | This case indicates that a long-standing growth hormone deficiency and hypogonadism
may lead to LC as a type of burn-out non-alcoholic steatohepatitis. | 29115108 | "
| Inflammation, Dissection of aorta, Data types - Address | Altered Intercellular Communication | Aortic dissection (AD) results from the imbalance between synthesis and degradation of extracellular matrices in aortic wall, which is characterized by chronic inflammation. | 29115411 |
| Inflammation, Dental caries | Altered Intercellular Communication | Dental examinations were performed to assess the presence of gingival inflammation, dental caries prevalence (DMFT>=1) and dental caries experience (mean DMFT). | 29116296 |
"
| Inflammation | Altered Intercellular Communication | Histologic evaluation indicated the presence of
fibrotic changes, associated with granulation tissue and rare cellular elements, compatible with chronic
inflammation. | 29117664 | "
| Inflammation, Disorder of Achilles tendon, Rupture | Altered Intercellular Communication | Chronic inflammation is a feature of Achilles tendinopathy and rupture. | 29118051 |
| Inflammation, Disease | Altered Intercellular Communication | Recent investigation of human tissue and cells from positional tendons such as the rotator cuff has clarified the importance of inflammation in the development and progression of tendon disease. | 29118051 |
| Inflammation, Disorder of Achilles tendon, Rupture | Altered Intercellular Communication | Using tissue biopsies from patients, we investigated if inflammation is a feature of Achilles tendinopathy and rupture. | 29118051 |
| Inflammation | Altered Intercellular Communication | Tissue and cells derived from tendinopathic and ruptured Achilles tendons show evidence of chronic (non-resolving) inflammation. | 29118051 |
| Inflammation | Altered Intercellular Communication | Differences seen in the profile of ruptured Achilles are likely to be attributable to a superimposed phase of acute inflammation and neo-vascularisation. | 29118051 |
| Inflammation | Altered Intercellular Communication | Strategies that target chronic inflammation are of potential therapeutic benefit for patients with Achilles tendon disease. | 29118051 |
| Inflammation, Infantile Colic, Crying | Altered Intercellular Communication | Impact of Lactobacillus reuteri colonization on gut microbiota, inflammation, and crying time in infant colic. | 29118383 |
| Colonization, Gastrointestinal inflammation | Altered Intercellular Communication | There were no differences in E. coli colonization rates or densities, microbial diversity or intestinal inflammation by L. reuteri colonization status. | 29118383 |
| Asthmatic Airway Remodeling | Altered Intercellular Communication | Exposure-response relationships are inconsistent in subjects with suspected asthmatic airway inflammation (FeNO >=50 ppb). | 29118577 |
| ARCN1 gene, Asthmatic Airway Remodeling, Asthma, Asthma-Chronic Obstructive Pulmonary Disease Overlap Syndrome | Altered Intercellular Communication | More careful risk assessment is needed in occupational inhalation exposure, since COPD with asthmatic airway inflammation, or asthma-COPD overlapping syndrome, may have the distinguishing features of both COPD and asthma. | 29118577 |
| Inflammation, Coronary Arteriosclerosis | Altered Intercellular Communication | Balance of Fatty Acids and Their Correlations with Parameters of Lipid Metabolism and Markers of Inflammation in Men with Coronary Atherosclerosis. | 29119389 |
| Inflammation, Coronary Arteriosclerosis | Altered Intercellular Communication | We studied the balance of fatty acids and their correlation with parameters of lipid metabolism and inflammation markers in men with coronary atherosclerosis. | 29119389 |
| Inflammation, Atherosclerosis | Altered Intercellular Communication | Lipid metabolism disturbances in coronary atherosclerosis were accompanied by changes in not only lipid spectrum and inflammation markers, but also fatty acids balance. | 29119389 |
"
| Inflammation, Metabolic Syndrome X, Diabetes Mellitus, Obesity, Osteopenia | Altered Intercellular Communication | Bone Mineral Density in Relation to Metabolic Syndrome Components in Postmenopausal Women With Diabetes Mellitus Type 2 Diabetes mellitus type 2 is associated with greater bone mineral density (BMD)
due to obesity, although rapid bone loss observed over time could be explained by elevated chronic
inflammation. | 29120134 | "
| Presenile dementia, Inflammation, Data types - Address | Altered Intercellular Communication | We confirm established associations between AD pathology and dementia, albeit with increased, presumably aging-related variability, and identify sets of co-expressed genes correlated with pathological tau and inflammation markers. | 29120328 |
| Inflammation, Choline Dehydrogenase, Mitochondrial | Altered Intercellular Communication | KEGG pathway and gene ontology (GO) analysis revealed that those differentially expressed genes related to inflammation, lipid metabolism and myocardial processes were particularly noted in the CHD group, but not in non-CHD. | 29121163 |
| Inflammation, Coronary Arteriosclerosis, Choline Dehydrogenase, Mitochondrial | Altered Intercellular Communication | Particularly, those genes related to inflammation, lipid metabolism and myocardial processes are differentially expressed in PVAT-CA and PVAT-ITA in CHD patients, suggesting an important role of PVAT in the development of coronary atherosclerosis. | 29121163 |
| Crohn Disease, Malignant Head and Neck Neoplasm | Altered Intercellular Communication | Managing head and neck malignancy arising in a field of Crohn disease inflammation: Report of a case. | 29121377 |
| Malaria, Anemia | Altered Intercellular Communication | Malaria exacerbates inflammation-associated elevation in ferritin and soluble transferrin receptor with only modest effects on iron deficiency and iron deficiency anaemia among rural Zambian children. | 29121448 |
| Inflammation, Malaria | Altered Intercellular Communication | We estimated the unadjusted ID or IDA prevalence, and then adjusted for inflammation alone (IDI or IDAI ) or inflammation and malaria (IDIM or IDAIM ). | 29121448 |
| Inflammation, muscle mass | Altered Intercellular Communication | The aging process is associated with several changes in the elderly such as the decrease in cardiorespiratory fitness, strength and muscle mass, in addition to chronic low-grade inflammation. | 29121681 |
| Inflammation | Altered Intercellular Communication | Detection of Aa from preadolescent African American children was associated with signs of periodontal inflammation. | 29122069 |
| Diabetic Nephropathy, Inflammation | Altered Intercellular Communication | Association of TNFR1 with markers of systemic inflammation and adipose stress indicates that TNFR1 may be a biomarker of these processes as components of the pathogenesis of diabetic kidney disease. | 29122448 |
| Inflammation, Trauma, Nervous System, Hyperglycemia, Hypoxia, Diabetes Mellitus | Altered Intercellular Communication | Proposed mechanisms of neuronal damage caused by diabetes that are downstream of hyperglycemia and/or loss of insulin signaling include ischemic hypoxia, inflammation and loss of neurotrophic support. | 29122628 |
| Inflammation, Liver carcinoma | Altered Intercellular Communication | Irrespective of the underlying aetiology, 90% of hepatocellular carcinomas arise and progress on a background of chronic inflammation. | 29123264 |
| Malignant neoplasm of liver, TNM Staging System, Neoplasm Metastasis, Neoplasms | Altered Intercellular Communication | In both UK and Hong Kong cohorts, neutrophils, platelets, lymphocytes, the neutrophil/lymphocyte ratio (NLR) and the Systemic Immune-Inflammation Index (SII) correlated stepwise, either increasing or decreasing (lymphocytes), with tumour node metastasis (TNM) and Childs-Pugh stage, PST and consequently with the combined Barcelona Clinic for Liver Cancer stage. | 29123264 |
| Gingivitis, Metabolic Syndrome X | Altered Intercellular Communication | Association between metabolic syndrome and gingival inflammation in obese children. | 29124887 |
| Granulomatous inflammation, Primary malignant neoplasm, Malignant Neoplasms | Altered Intercellular Communication | Specifically, TB provided clear histological diagnosis of malignancy (either primary lung cancer or metastases from extra-thoracic cancer) in 30/46 (65.2%) patients and granulomatous inflammation in 11/46 (23.9%) of patients. | 29124891 |
| Fibrous, Fatty degeneration, Inflammation, Nodularity | Altered Intercellular Communication | Histological features such as nodularity, fibrous bands, ductular proliferation, steatosis, ballooned hepatocytes and lymphocytic inflammation were also scored. | 29127141 |
| Inflammation, Fatty degeneration, Fibrous | Altered Intercellular Communication | Copper deposition in IHA was significantly associated with presence of lymphocytic inflammation (P=0.04) but not associated with features like nodularity, fibrous bands, ductular proliferation, ballooned hepatocytes and steatosis (P>0.05, for all). | 29127141 |
| Inflammation | Altered Intercellular Communication | Increased chronic inflammation is believed to play a key role in the development of CRCI related to chemotherapy but studies assessing this hypothesis specifically in patients receiving chemotherapy are rare. | 29128118 |
| Inflammation, Nasopharyngeal carcinoma, Neoplasms | Altered Intercellular Communication | Based on current concepts in tumour related inflammation the inflammatory marker, neutrophil-lymphocyte ratio was tested to find its relationship with prognosis in nasopharyngeal carcinoma. | 29128472 |
| Osteoarthritis, Knee, Inflammation, Pain Distress Question | Altered Intercellular Communication | Monocyte activation is elevated in women with knee-osteoarthritis and associated with inflammation, BMI and pain. | 29128509 |
| Degenerative polyarthritis, Inflammation | Altered Intercellular Communication | Low-grade inflammation occurs in OA and correlates with disease severity and progression. | 29128509 |
| Degenerative polyarthritis, Inflammation | Altered Intercellular Communication | Since monocyte development and function is altered by systemic inflammation, we analyzed monocyte numbers and function between individuals with knee OA and healthy age- and sex-matched controls. | 29128509 |
| Degenerative polyarthritis, Inflammation | Altered Intercellular Communication | We analyzed markers of soluble and cellular inflammation in peripheral blood of women with knee OA and compared them to healthy age- and sex-matched controls. | 29128509 |
| Inflammation | Altered Intercellular Communication | Modulating systemic inflammation and monocyte recruitment to the synovium could be of therapeutic benefit. | 29128509 |
| Neurocognitive Disorders, Inflammation, Hand | Altered Intercellular Communication | HIV-1-associated neurocognitive disorders (HAND) is associated with blood-brain-barrier (BBB) inflammation, and inflammation involves toll-like receptors (TLRs) signaling. | 29128906 |
| Inflammation, Acquired Immunodeficiency Syndrome, physiopathological, Hand | Altered Intercellular Communication | These data suggest that viral immune recognition via endothelial TLR3 is involved in endothelial inflammation and BBB dysfunction in HIV/AIDS and HAND. | 29128906 |
| Refractory anemias, Inflammation | Altered Intercellular Communication | 5-HETE, 15-HETE, 9-HODE, and 13-HODE levels were significantly increased in HDL and LDL from patients with active RA (n = 10) compared to healthy controls (n = 8) and correlated significantly with measures of systemic inflammation, particularly in HDL (r = 0.65-0.80, p values < 0.004). | 29129008 |
| Inflammation, Atherosclerosis | Altered Intercellular Communication | Aging is an important determinant of the rate of atherosclerosis development, mainly through low-grade inflammation. | 29129737 |
| Inflammation, Fibrosis Assessment | Altered Intercellular Communication | Galectin-3 plays an important role in modulating cardiac inflammation and fibrosis. | 29129812 |
| Inflammation, Urticaria, Chronic Spontaneous Urticaria | Altered Intercellular Communication | Elevated levels of C-reactive protein (CRP), a sensitive marker of inflammation, have been consistently reported in chronic spontaneous urticaria (CSU). | 29130488 |
| Inflammation, Cachexia, Chronic Kidney Diseases | Altered Intercellular Communication | Protein energy wasting (PEW) is a common syndrome in patients with chronic kidney disease, related to changes in hydration status, decreased food intake and inflammation. | 29130711 |
| Inflammation, Leukocytosis, Neutrophilia (finding) | Altered Intercellular Communication | Here, markers for inflammation such as CRP, leukocytosis, and neutrophilia were elevated in 50-73% of the PG patients. | 29130957 |
| Inflammation, Malnutrition | Altered Intercellular Communication | These are associated with malnutrition and inflammation, and hence, may provide benefit in predicting mortality among hemodialysis patients. | 29130984 |
| Periodontitis, Psoriasis | Altered Intercellular Communication | Periodontitis and psoriasis are suggested to be co-occurring, chronic inflammatory conditions with overlapping characteristics. | 29131099 |
| Inflammation, Kit Ligand, human, Endothelial dysfunction | Altered Intercellular Communication | Nesfatin-1 could play a role in the pathogenesis of SCF phenomenon with mechanisms such as inflammation and endothelial dysfunction. | 29131290 |
| Inflammation, Disease | Altered Intercellular Communication | Inflammation plays an important role in the pathophysiology of many diseases and could cause damage by means of oxidative stress. | 29131698 |
| Inflammation | Altered Intercellular Communication | Pulmonary and hepatic 18F-fluoro-deoxy-D-glucose (18F-FDG) uptake was calculated to determine the status of inflammation by 18F-fluoro-deoxy-D-glucose-positron emission tomography (18FDG-PET) scan. | 29131698 |
| vascular inflammations | Altered Intercellular Communication | Internal tissue references for 18Fluorodeoxyglucose vascular inflammation imaging: Implications for cardiovascular risk stratification and clinical trials. | 29131857 |
| Inflammation | Altered Intercellular Communication | However, variation in blood activity may mask artery wall signal reflective of inflammation, which requires normalization. | 29131857 |
| Inflammation | Altered Intercellular Communication | Increased Th1/Th17 Responses Contribute to Low-Grade Inflammation in Age-Related Macular Degeneration. | 29132135 |
| Preterm premature rupture of membranes (disorder) | Altered Intercellular Communication | Infection induced-inflammation and other risk factors for spontaneous preterm birth (PTB) and preterm premature rupture of membranes (pPROM) may cause a redox imbalance, increasing the release of free radicals and consuming antioxidant defenses. | 29132320 |
| Malignant neoplasm of endometrium, Endometritis | Altered Intercellular Communication | The major risk factors for endometrial cancer are related to the exposure of endometrium to estrogens not opposed to progestogens, that can lead to a chronic endometrial inflammation. | 29132343 |
| Inflammation, Primary malignant neoplasm | Altered Intercellular Communication | Diet may play a role in cancer risk by modulating chronic inflammation. | 29132343 |
| Inflammation | Altered Intercellular Communication | The neutrophil-lymphocyte ratio (NLR) is a recognized marker of inflammation associated with poor outcomes in various clinical situations. | 29132702 |
| Chronic Kidney Diseases, Renal tubular disorder, Endothelial dysfunction, Nephritis | Altered Intercellular Communication | Serum uric acid concentrations increase in chronic kidney disease (CKD) and may lead to tubular injury, endothelial dysfunction, oxidative stress, and intrarenal inflammation. | 29132945 |
| Airway structure, Asthma | Altered Intercellular Communication | In addition, more activity and less sedentary time would be associated with better clinical outcomes and markers of systemic and airway inflammation in people with severe asthma. | 29133222 |
| Inflammation, Asthma | Altered Intercellular Communication | Adults with severe asthma (n = 61) and sex- and age-matched controls (n = 61) underwent measurement of lung function, exercise capacity, asthma control, health status, and airway and systemic inflammation. | 29133222 |
| Inflammation, Asthma | Altered Intercellular Communication | Higher levels of activity and lower levels of sedentary time are associated with better exercise capacity, asthma control, and lower levels of systemic inflammation. | 29133222 |
| HD Term Type, Inflammation, Muscle damage | Altered Intercellular Communication | Moreover, moderate intensity intradialytic exercise did not exacerbate the systemic inflammation or induce muscle damage during HD therapy. | 29134614 |
| Inflammation, Chronic Kidney Diseases | Altered Intercellular Communication | Zonulin, inflammation and iron status in patients with early stages of chronic kidney disease. | 29134616 |
| Inflammation | Altered Intercellular Communication | There were no statistically significant differences in zonulin concentration between patients with and without inflammation. | 29134616 |
| Inflammation, hepcidin | Altered Intercellular Communication | Zonulin was significantly correlated with hepcidin only in patients with inflammation. | 29134616 |
| Cerebral Amyloid Angiopathy, Inflammation | Altered Intercellular Communication | Cerebral amyloid angiopathy associated with inflammation: A systematic review of clinical and imaging features and outcome. | 29134927 |
| Cerebral Amyloid Angiopathy, Inflammation, Deposition | Altered Intercellular Communication | Background Cerebral amyloid angiopathy associated with inflammation is an increasingly recognized condition, characterized by an inflammatory response to the vascular deposits of b-amyloid within the brain that are the hallmark of cerebral amyloid angiopathy. | 29134927 |
| Vasculitis, Inflammation, Vasculitis, CTCAE | Altered Intercellular Communication | Two main patterns of this inflammatory response have been identified to date: one involving a perivascular inflammatory cell infiltrate (cerebral amyloid angiopathy-related inflammation); the other a transmural vasculitic process (A-beta related angiitis). | 29134927 |
| Cerebral Amyloid Angiopathy, Inflammation, Cerebral Hemorrhage | Altered Intercellular Communication | Unlike cerebral amyloid angiopathy itself, which predisposes to intracerebral hemorrhage and has no known treatment, cerebral amyloid angiopathy associated with inflammation typically presents in diverse ways and diagnosis may be challenging and delayed. | 29134927 |
| Vasculitis | Altered Intercellular Communication | Summary of review We identified 213 distinct pathologically proven cases of cerebral amyloid angiopathy-related inflammation/A-beta related angiitis, from 104 publications. | 29134927 |
| Cerebral Amyloid Angiopathy, Inflammation | Altered Intercellular Communication | The clinical presentation, imaging features, pathology, treatment, and outcomes of cerebral amyloid angiopathy associated with inflammation are described. | 29134927 |
| Vascular Diseases, Inflammation, Impaired cognition, Seizures, Headache | Altered Intercellular Communication | Conclusions Cerebral amyloid angiopathy associated with inflammation is an important and increasingly recognized clinical condition, which affects the older patient population and presents most commonly with cognitive decline, seizures, and headaches. | 29134927 |
| Inflammation, Heart valve disease, Conductive hearing loss | Altered Intercellular Communication | He was diagnosed to have inflammation of the tracheobronchial cartilage, cardiac valvulopathy and conductive hearing loss after intensive diagnostic studies. | 29135403 |
| Inflammation | Altered Intercellular Communication | Chronic low grade inflammation is a fundamental mechanism of aging. | 29135455 |
| Fibrosis Assessment, FAM126A gene | Altered Intercellular Communication | NLR and AAR, when combined to produce an inflammation-based index and fibrosis score, is an independent marker of poor prognosis in patients with HCC receiving TACE. | 29137051 |
| Inflammation | Altered Intercellular Communication | A subsequent brain biopsy showed necrotizing granulomatous inflammation suggestive of NS. | 29137054 |
| Airway structure, Asthma | Altered Intercellular Communication | Virus-triggered exacerbation in allergic asthmatic children: neutrophilic airway inflammation and alteration of virus sensors characterize a subgroup of patients. | 29137638 |
| Airway structure, Infected | Altered Intercellular Communication | Airway inflammation in infected patients was characterized by significantly higher IL-5 concentration and eosinophil count. | 29137638 |
| Airway structure | Altered Intercellular Communication | This subgroup is characterized by altered PRR function and a different pattern of airway inflammation. | 29137638 |
| Inflammation, HIV-1 Infection Pathway, HIV Enteropathy, Endothelial dysfunction, Cerebrovascular Disorders | Altered Intercellular Communication | Recently "HIV-associated vasculopathy" has been used to describe the cerebrovascular disorder related to HIV-1 infection that is caused by the endothelial dysfunction induced from chronic inflammation and cytokine imbalances due to HIV-1 infection. | 29138020 |
| ARCN1 gene, Inflammation, Pulmonary Emphysema, Bronchiectasis | Altered Intercellular Communication | Inflammation and chronic colonization of Haemophilus influenzae in sputum in COPD patients related to the degree of emphysema and bronchiectasis in high-resolution computed tomography. | 29138549 |
| ARCN1 gene, Inflammation, Exacerbation, Airway structure | Altered Intercellular Communication | The presence of bacteria in the lower airways in COPD results in inflammation, further airway structural damage, and might lead to repeated exacerbations. | 29138549 |
| Inflammation, Colonization, Pulmonary Emphysema, Bronchiectasis | Altered Intercellular Communication | We have previously shown that chronic colonization of Haemophilus influenzae during stable disease is related to increased inflammation, and we now aimed to relate previous findings of bacterial colonization and inflammation to the degree of radiological findings of bronchiectasis and emphysema. | 29138549 |
| Inflammation, Pulmonary Emphysema, Bronchiectasis | Altered Intercellular Communication | During exacerbation, there was no longer any correlation between emphysema degree and inflammation, but patients with bronchiectasis showed higher sputum purulence score than patients without bronchiectasis. | 29138549 |
| Inflammation, Colonization, Pulmonary Emphysema, Bronchiectasis | Altered Intercellular Communication | The presence of emphysema is more related to inflammation, while bronchiectasis is associated with bacterial colonization. | 29138549 |
| ARCN1 gene, Inflammation | Altered Intercellular Communication | Longevity gene, SIRT1, is reported to be involved in the pathogenesis of COPD by regulating the signaling pathways of oxidative stress, inflammation, and aging. | 29138552 |
| Inflammation, Pulmonary Emphysema | Altered Intercellular Communication | Inflammation, apoptosis, and oxidative stress levels were severe in the CSE-treated emphysema mice compared with the control group, which was inhibited by the overexpression of PRMT6. | 29138553 |
| Inflammation, Pulmonary Emphysema | Altered Intercellular Communication | The overexpression of PRMT6 might inhibit inflammation, apoptosis, and oxidative stress in CSE-induced emphysema mediated by H3R2me2a. | 29138553 |
| Inflammation, Unspecified visual loss | Altered Intercellular Communication | These results provide a comprehensive framework for the role of Ab42 in visual loss due to inflammation present with aging and offer some clues for fruitful avenues for the study of healthy aging. | 29138750 |
| Sepsis, Inflammation | Altered Intercellular Communication | Taken together, the results suggested that Lp-PLA2, with respect to other markers of inflammation, may have a role as a prognostic marker in sepsis, and provide background evidence for further trials to evaluate the clinical and pathophysiologic roles of Lp-PLA2 in sepsis. | 29138849 |
| Inflammation, Tooth Loss, Cardiovascular Diseases | Altered Intercellular Communication | Associations among tooth loss, systemic inflammation and antibody titers to periodontal pathogens in Japanese patients with cardiovascular disease. | 29139559 |
| Inflammation | Altered Intercellular Communication | Inhibition of neurogenesis in our patient, which cannot be explained by the fulminant nature of his symptoms, may be related to inflammation and immune response. | 29141824 |
| Inflammation, Infection, Colorectal Carcinoma | Altered Intercellular Communication | Worse Preoperative Status Based on Inflammation and Host Immunity Is a Risk Factor for Surgical Site Infections in Colorectal Cancer Surgery. | 29142183 |
| Primary malignant neoplasm, Malnutrition, Cachexia | Altered Intercellular Communication | The modified Glasgow Prognostic Score (mGPS) is an inflammation-based measure of malnutrition that reflects a state of cachexia in cancer patients. | 29142183 |
| Kidney Failure, Chronic, Inflammation | Altered Intercellular Communication | Complications of end-stage renal disease (ESRD) are critically related to inflammation. | 29142271 |
| Kidney Failure, Chronic, Inflammation, palladium, HD Term Type | Altered Intercellular Communication | We therefore studied faecal microbiome composition and function as well as inflammation and gut permeability in 30 patients with ESRD (15 HD, 15 PD) and compared to 21 healthy controls. | 29142271 |
| palladium, HD Term Type, Gastrointestinal inflammation | Altered Intercellular Communication | In HD but not in PD, changes in microbiome composition were associated with an increase in c-reactive protein (CRP) but not with intestinal inflammation or gut permeability. | 29142271 |
| Inflammation | Altered Intercellular Communication | These differences are associated with systemic inflammation and cannot completely be explained by dialysis vintage. | 29142271 |
| Inflammation, Vascular System Injuries | Altered Intercellular Communication | Inflammation mediated through the IL-8 pathway predicted microvascular injury while Flt-1, a potential marker of angiogenesis and endothelial repair, might have a significant protective role. | 29145197 |
| Inflammation, Fibrosis Assessment | Altered Intercellular Communication | Degree of inflammation and interstitial fibrosis in the cortex of transplanted kidneys were estimated semi-quantitatively. | 29146138 |
| Inflammation, Cardiovascular Diseases | Altered Intercellular Communication | Markers of inflammation, including plasma C-reactive protein (CRP), are associated with an increased risk of cardiovascular disease, and it has been suggested that this association is causal. | 29146277 |
| Inflammation, Chronic Kidney Diseases, Cardiovascular Diseases | Altered Intercellular Communication | However, the relationship between inflammation and cardiovascular disease has not been extensively studied in patients with chronic kidney disease. | 29146277 |
| ARCN1 gene, Inflammation | Altered Intercellular Communication | Clinical trials targeting eosinophilic inflammation in COPD should consider assessing sputum eosinophils. | 29146301 |
| Airway structure | Altered Intercellular Communication | Microbial diversity and relative abundance of Streptococcus, Prevotella and Veillonella were inversely associated with airway inflammation. | 29146601 |
| Inflammation | Altered Intercellular Communication | Increased Levels of sRAGE in Diabetic CKD-G5D Patients: A Potential Protective Mechanism against AGE-Related Upregulation of Fibroblast Growth Factor 23 and Inflammation. | 29147074 |
| Inflammation, Cardiac complication | Altered Intercellular Communication | Indeed, its increase could be a potential protective mechanism against the increased risk of cardiovascular complications related to AGEs and inflammation. | 29147074 |
| Memory Disorders | Altered Intercellular Communication | The changing hormonal milieu during the menopausal transition may contribute to the development of memory disorders. | 29147956 |
| Refractory anemias, Inflammation | Altered Intercellular Communication | These results indicate that the mRNA expression of PADI2, PADI4 and Sp1 is upregulated in RA BM CD34+ cells independently of the systemic inflammation or treatment regimen. | 29148420 |
| Inflammation, Hepatobiliary Disorder, Prostatic Diseases, Ulcerative Colitis | Altered Intercellular Communication | Studies discussing inflammation and oxidative stress state that these conditions are known contributors in the pathogenesis of cholestatic diseases and ulcerative colitis, and studies examining patients with liver disease have found decreased antioxidant status and significant elevation of lipid peroxides as compared with healthy subjects. | 29148959 |
| Inflammation, Leucocytic infiltrate, Congenital Abnormality | Altered Intercellular Communication | Histological analysis of the placenta showed moderate inflammatory infiltration; however, whether fetal malformation in NMOSD is related to inflammation and AQP4-IgG remains to be determined. | 29149698 |
| Inflammation, Asthma | Altered Intercellular Communication | Sensitization to Staphylococcus aureus enterotoxins (SEs) augments eosinophilic inflammation in asthma. | 29150068 |
| Inflammation, Asthma | Altered Intercellular Communication | To clarify the role of SEs on clinical indexes, including eosinophilic inflammation and lung function in smokers with asthma. | 29150068 |
| Inflammation, Asthma, Chronic Obstructive Airway Disease | Altered Intercellular Communication | In current or ex-smokers with asthma, the association of sensitization to SEs with eosinophilic inflammation, airflow limitation, or treatment steps was determined. | 29150068 |
| Inflammation, Asthma | Altered Intercellular Communication | Sensitization to SEs is increased in smokers with asthma, and it may be a marker of eosinophilic inflammation and severe asthma in smokers with asthma. | 29150068 |
| allergic inflammation | Altered Intercellular Communication | The tryptophan metabolic pathway mediated by indolamine 2,3-dioxygenase (IDO), a tryptophan-degrading enzyme, plays an important role in controlling the development of allergic inflammation. | 29150070 |
| Allergic | Altered Intercellular Communication | The fractional concentration of exhaled nitric oxide (FeNO) is closely associated with the allergic state and is extensively used for the clinical evaluation of airway allergic inflammation. | 29150070 |
| Inflammation, Metabolic Syndrome X | Altered Intercellular Communication | Three linking pathways were revealed: sedentariness, inflammation and metabolic syndrome. | 29150168 |
| Inflammation, Bacterial Infections | Altered Intercellular Communication | When it feeds on the blood through the scalp of its host, the anticoagulant in its saliva causes scalp inflammation and itching, and consequent scratching by the host causes further inflammation from bacterial infection. | 29150362 |
| Acute Lung Injury, Non-Small Cell Lung Carcinoma, Pneumonitis | Altered Intercellular Communication | Pretreatment advanced lung cancer inflammation index (ALI) for predicting early progression in nivolumab-treated patients with advanced non-small cell lung cancer. | 29150906 |
| Acute Lung Injury, Non-Small Cell Lung Carcinoma, Pneumonitis | Altered Intercellular Communication | Because the baseline advanced lung cancer inflammation index (ALI) is reportedly associated with patient outcomes, we investigated whether the pretreatment ALI is prognostic in NSCLC patients treated with nivolumab. | 29150906 |
| HD Term Type, Inflammation | Altered Intercellular Communication | Thus, uremic toxins may stimulate NF-kB mRNA and decrease Nrf2 expression in HD patients and, consequently, trigger inflammation and oxidative stress. | 29151180 |
| Inflammation, Thrombosis | Altered Intercellular Communication | Objective The neutrophil-to-lymphocyte ratio (NLR) is an inflammation marker that can be used to detect atrial inflammatory changes, which may contribute to a reduced left atrial (LA) function and thrombosis. | 29151509 |
| Inflammatory disease of mucous membrane | Altered Intercellular Communication | Furthermore, lower FC baseline values significantly correlated to the presence of mucosal healing in endoscopy (69.0 mg/g, 30.0-128.0 vs 481.0, 278.0-600.0, in those with mucosal inflammation, median with IQR, P < 0.001). | 29151692 |
| Inflammation, Anemia, Chronic Kidney Diseases | Altered Intercellular Communication | Chronic inflammation and chronic renal failure were the most frequent causes of anemia in our population, and in >35% of patients a multifactorial anemia was diagnosed. | 29153343 |
| Inflammation, Anemia | Altered Intercellular Communication | Our data confirm the high prevalence of anemia in patients hospitalized in an Internal Medicine Department, with a remarkable burden of mild forms, and of chronic inflammation's pathogenic mechanism. | 29153343 |
| Inflammation, Asthma | Altered Intercellular Communication | IL1RL1 SNPs may characterize the eosinophilic phenotype with greater eosinophilic inflammation in the Japanese asthma cohort. | 29153414 |
| Airway structure, ARCN1 gene | Altered Intercellular Communication | Eosinophilic airway inflammation characterizes a chronic obstructive pulmonary disease (COPD) phenotype that requires more study. | 29153881 |
| Cryptococcus, Choroiditis | Altered Intercellular Communication | In the second patient, ILV recurred secondary to choroid plexus inflammation caused by cryptococcal infection. | 29155114 |
| Inflammation | Altered Intercellular Communication | This was associated with increased sterile inflammation in the skin in the same subjects related to p38 mitogen-activated protein kinase-related proinflammatory cytokine production (P < .0007). | 29155150 |
| Inflammation | Altered Intercellular Communication | Excessive inflammation in the skin early after antigen challenge retards antigen-specific immunity. | 29155150 |
| Inflammation | Altered Intercellular Communication | Surfactant protein-D (SP-D) is a collectin, which plays an important role in airway protection and inflammation. | 29155458 |
| Inflammation, Colorectal Carcinoma | Altered Intercellular Communication | Chronic inflammation is a key component in the development and progression of colorectal cancer (CRC). | 29155516 |
| Inflammation | Altered Intercellular Communication | A notable hallmark of the inflammation process is the release of pro-inflammatory cytokines by infiltrating cells of the immune system. | 29155516 |
| Rheumatoid Arthritis, Atherosclerosis | Altered Intercellular Communication | Considerable evidence supports the hypothesis that risk of atherosclerosis is increased by chronic inflammatory conditions accompanying diseases such as rheumatoid arthritis and HIV, as well as general ageing, and that this risk is predicted by monocyte activation. | 29155735 |
| Inflammation, Lung Injury, Traumatic injury | Altered Intercellular Communication | In a severe trauma model, sustained changes in terms of lung injury and inflammation are determined at day 3 post-trauma. | 29156155 |
| Inflammation, Depression, CTCAE | Altered Intercellular Communication | Quality of life is associated with chronic inflammation in depression: A cross-sectional study. | 29156363 |
| Inflammation, Depression, CTCAE | Altered Intercellular Communication | Inflammation may play a crucial role in the pathophysiology of depression. | 29156363 |
| Inflammation, Depression, CTCAE | Altered Intercellular Communication | However, the association between chronic inflammation and health outcomes in depression remains unclear, particularly for patient-reported outcomes. | 29156363 |
| Inflammation, Depression, CTCAE | Altered Intercellular Communication | The design of this study is cross-sectional and there are no conclusions about the directionality of the association between QoL and inflammation in depression. | 29156363 |
| Inflammation, Depression, CTCAE | Altered Intercellular Communication | This paves the way for interventions to act both on inflammation and QoL in patients with depression. | 29156363 |
| Inflammation, Diabetes Mellitus, Non-Insulin-Dependent | Altered Intercellular Communication | Although high levels of sitting time are adversely related to health, it is unclear whether moving from sitting to standing provides a sufficient stimulus to elicit benefits upon markers of chronic low-grade inflammation in a population at high risk of type 2 diabetes (T2DM). | 29157133 |
| Inflammation, Coronary Artery Disease | Altered Intercellular Communication | Ozone exposure is associated with acute changes in inflammation, fibrinolysis, and endothelial cell function in coronary artery disease patients. | 29157250 |
| Cyst, Inflammation, Dental Leakage | Altered Intercellular Communication | Retinal cysts are formed by accumulation of fluid in the retina caused by leakages from inflammation or vitreous fractures. | 29157443 |
| Inflammation, Hallopeau-Siemens Disease, Neoplasms, Tissue damage, Damage | Altered Intercellular Communication | Sporadic cSCCs show signs of UV damage, whereas RDEB cSCCs have higher mutational rates and display tissue damage, inflammation and subsequent remodeling of the dermal ECM as tumor initiating factors. | 29158163 |
| Refractory anemias, Inflammation | Altered Intercellular Communication | Bioinformatics analysis confirmed that CASP5 was related to the development of inflammation, which is the main feature of RA. | 29158166 |
| Refractory anemias, Inflammation | Altered Intercellular Communication | In conclusion, CASP5 may contribute to the development of RA by mediating inflammation. | 29158166 |
| Dermatitis | Altered Intercellular Communication | Specific deletion of suppressor of cytokine signaling 3 (Socs3) in keratinocytes can cause severe skin inflammation with infiltration of immune cells. | 29158586 |
| Inflammatory abnormality of the eye | Altered Intercellular Communication | Being a multifactorial disease, it is characterized by oxidative stress in the cornea and commonly complicated by ocular surface inflammation. | 29158874 |
| Inflammation, Observation Method - Coagulation, Endothelial dysfunction, Hemorrhagic Fever, Crimean | Altered Intercellular Communication | Evaluation of the associations between endothelial dysfunction, inflammation and coagulation in Crimean-Congo hemorrhagic fever patients. | 29159591 |
| Inflammation, Endothelial dysfunction | Altered Intercellular Communication | There is no relationship between increased inflammation and endothelial dysfunction. | 29159591 |
| Inflammation, Pterygium Of Conjunctiva And Cornea | Altered Intercellular Communication | HBD-2 expression that might be stimulated by inflammatory cytokines may be related to inflammation and fibrovascular proliferation and may play a role in pterygium pathogenesis. | 29160535 |
| Inflammation, Amyloidosis, Carpal Tunnel Syndrome | Altered Intercellular Communication | The deposition of b2-microglobulin induced by reactive inflammation causing carpal tunnel syndrome (CTS) is one of the complications of dialysis-related amyloidosis in maintenance hemodialysis (MHD) patients. | 29161700 |
| Inflammation, Hypersensitivity, Tetanus | Altered Intercellular Communication | Most of the allergic reactions to tetanus toxoid vaccine usually present with unspecific symptoms of local inflammation. | 29162425 |
| Inflammation | Altered Intercellular Communication | This observational case-control study attempted to identify factors associated with TMJD development, particularly inflammation. | 29162786 |
| Autoimmune Diseases | Altered Intercellular Communication | In conclusion, autoimmune diseases and inflammatory conditions are associated with increased risk of TMJD. | 29162786 |
| Uveitic glaucoma | Altered Intercellular Communication | We identified uveitic glaucoma patients with AGV surgery alone and AGV surgery combined with fluocinolone implant from the Massachusetts Eye and Ear Ocular Inflammation Database. | 29162989 |
| Inflammation, Glaucoma, CTCAE | Altered Intercellular Communication | Compared to the AGV group, the AGV + fluocinolone group used fewer glaucoma medications (0.28 vs 1.30 [P = 0.01]) and had better inflammation control (P = 0.02). | 29162989 |
| Diverticulitis, Diverticulum, Colitis | Altered Intercellular Communication | Diverticular colitis is chronic inflammation of the colon where diverticula are present. | 29164476 |
| Malignant neoplasm of skin, Inflammatory disorder | Altered Intercellular Communication | To examine immunoreactivity to VDR and CYP24A1 in mast cells from normal human skin, keratinocyte skin cancers, and disorders of chronic inflammation. | 29165303 |
| Inflammation, Tumor necrosis | Altered Intercellular Communication | Immune homeostasis favored inflammation, and a negative correlation between the circulating tumor necrosis factor-alpha and the proportions of CD4+CD25+CD62L+ cells (r = -0.698, p < 0.05) in patients with AECOPD was found. | 29166179 |
| Fibrosis Assessment, Tissue Adhesions, Acute inflammation | Altered Intercellular Communication | The adjunct use of biologics (eg, viable umbilical tissue) may provide additional support and reduce postoperative inflammation, adhesions, and fibrosis. | 29166259 |
| Inflammation, Obesity | Altered Intercellular Communication | Low grade inflammation, potentially initiated by the intestinal microbiota, has been suggested to be a driving force in the development of insulin resistance in obesity. | 29166392 |
| Heredity, Traumatic injury, physiopathological | Altered Intercellular Communication | The etiology remains unknown, although factors such as trauma, hormonal dysfunction and heredity have been suggested. | 29166520 |
| Inflammation, Fever | Altered Intercellular Communication | Furthermore, he remained febrile and inflammation markers remained elevated despite antibacterial treatment. | 29166922 |
| Inflammation | Altered Intercellular Communication | Dysregulated inflammation is implicated in the pathobiology of aging, yet platelet-leukocyte interactions and downstream cytokine synthesis in aging remains poorly understood. | 29167233 |
| Inflammation, Bronchiectasis, Aortic Stiffness | Altered Intercellular Communication | In addition, we sought to compare these direct measures against calculated QRISK2 scores.Aortic stiffness, cardiac biomarkers and systemic inflammation were measured in 101 adults with stable bronchiectasis. | 29167299 |
| Inflammation, Symptom aggravating factors | Altered Intercellular Communication | In addition, frequent exacerbators had elevated serum C-reactive protein concentration, suggesting increased systemic inflammation (4.8 versus 2.2 mg*L-1, p=0.005). | 29167299 |
| Inflammation, Spinal Fractures | Altered Intercellular Communication | We demonstrated that trabecular bone score, a parameter of bone quality, was associated with systemic inflammation and was a significant determinant of vertebral fracture independent of bone mineral density. | 29167970 |
| Inflammation, Weight decreased | Altered Intercellular Communication | Systemic inflammation, as reflected by increased hsCRP levels, may be involved in deterioration of the trabecular microarchitecture in COPD-associated osteoporosis, whereas BMD decline is most strongly associated with weight loss. | 29167970 |
| Sleep-Disordered Breathing, Inflammation, Cardiovascular Diseases | Altered Intercellular Communication | Sleep-disordered breathing (SDB) is associated with cardiovascular disease and systemic inflammation in adults but this remains to be explored in children, especially in children with the most common form of SDB, i.e. | 29168015 |
| Inflammation, Sleep-Disordered Breathing | Altered Intercellular Communication | This pilot study investigated the relationship between the cardiovascular function and inflammation in children with mild SDB. | 29168015 |
| Inflammation | Altered Intercellular Communication | Inflammation may play a role in TC in combination with or independently of excess weight. | 29168186 |
| Inflammation, Atherosclerosis | Altered Intercellular Communication | Biomarkers of inflammation such as high-sensitivity C-reactive protein (hs-CRP) associate with subclinical atherosclerosis. | 29168363 |
| Inflammation, Panuveitis, Retinitis, Vitritis, Hypopyon | Altered Intercellular Communication | A 26-year-old man presented with bilateral panuveitis (hypopyon in the right eye, bilateral anterior segment inflammation, vitritis and retinitis). | 29170182 |
| Vitritis, Inflammation, Hypopyon, Retinal Detachment | Altered Intercellular Communication | The second patient, a 28-year-old man, presented with bilateral anterior segment inflammation, vitritis, exudative retinal detachment and hypopyon in the right eye. | 29170182 |
| Inflammation, GDC AJCC Clinical Stage Terminology | Altered Intercellular Communication | Lp-PLA2 was a marker of oxidative stress and inflammation, rather than an independent risk factor for ACS in young Chinese patients. | 29170433 |
| methyldopa, Inflammation, Blindness | Altered Intercellular Communication | A chronic low-level inflammation contributes to the pathogenesis of age-related macular degeneration (AMD), the most common cause of blindness in the elderly in Western countries. | 29170454 |
| Inflammation | Altered Intercellular Communication | In contrast to previous findings, CB2 activation increased, rather than reduced inflammation in RPE cells. | 29170454 |
| Inflammation, Nasopharyngeal carcinoma | Altered Intercellular Communication | BMAL1 mRNA was significantly reduced in nasopharyngeal carcinoma (4.67 +- 0.27 versus 6.64 +- 0.51 in chronic inflammation tissues, p = 0.002). | 29172799 |
| Pharyngitis, Nasopharyngeal carcinoma | Altered Intercellular Communication | Level of BMAL1 mRNA was assessed in tissue specimens from 36 nasopharyngeal carcinomas and 20 nasopharyngeal chronic inflammations using quantitative reverse transcriptase-polymerase chain reaction. | 29172799 |
| Inflammation, Cerebrovascular accident | Altered Intercellular Communication | Immunity and inflammation predictors for short-term outcome of stroke in young adults. | 29172921 |
| Amyloidosis | Altered Intercellular Communication | Amyloid A amyloidosis is a rare complication of chronic inflammatory conditions. | 29173691 |
| Adenocarcinoma of lung (disorder) | Altered Intercellular Communication | To systematically evaluate the prognostic value of nutrition/inflammation-based markers for recurrence-free survival (RFS) in pN2-stage IIIA lung adenocarcinoma patients. | 29173768 |
| Adenocarcinoma of lung (disorder), Neoplasms | Altered Intercellular Communication | The CAR was the best prognostic marker to predict tumor recurrence in pN2-stage IIIA lung adenocarcinoma patients among the 7 nutrition/inflammation-based markers. | 29173768 |
| Inflammation, Poliovirus Vaccine, Inactivated, Cyclophosphamide/Vincristine/Dacarbazine Regimen, Cardiovascular Diseases | Altered Intercellular Communication | IPV can significantly predispose women to a lifetime risk of developing cardiovascular disease (CVD) due to the effects of stress and inflammation. | 29173932 |
| Minimal Disseminated Disease | Altered Intercellular Communication | Together, these data implicate neuro-inflammation as playing a crucial role in MDD. | 29175309 |
| Inflammation, Myocarditis, CTCAE 5.0 | Altered Intercellular Communication | However, it was debatable whether the hypervascularity demonstrated by coronary PMCTA in the case of acute myocarditis was more prominent than the vascular images obtained in other cases without inflammation. | 29175582 |
| atherosclerotic, Coronary heart disease | Altered Intercellular Communication | Although 18F-fluorodeoxyglucose (FDG) uptake has emerged as a sensitive and reliable marker of atherosclerotic inflammation, its additive predictive value for future coronary disease in older subjects is unknown. | 29175654 |
| malignant disease, Coronary Artery Disease, Arteritis | Altered Intercellular Communication | In older subjects with no history of malignant disease or overt coronary artery disease, arterial inflammation evaluated by FDG uptake provides information on future occurrence of coronary artery events. | 29175654 |
| Glioma | Altered Intercellular Communication | Significance of systemic immune-inflammation index in the differential diagnosis of high- and low-grade gliomas. | 29175722 |
| Inflammation | Altered Intercellular Communication | Growth arrest-specific gene 6 (Gas6) is secreted by endothelial cells and is important for the activation of endothelium during inflammation. | 29176262 |
| Inflammation, Fracture | Altered Intercellular Communication | Association of Insulin-like Growth Factor-1, Bone Mass and Inflammation to Low-energy Distal Radius Fractures and Fracture Healing in Elderly Women Attending Emergency Care. | 29178313 |
| Inflammation, Fracture, Traumatic injury | Altered Intercellular Communication | Postmenopausal women, 55 years or older, with low-energy distal radius fractures occurring due to falling on slippery ground, indoors or outdoors, were recruited in the emergency department (ED) and followed 1 and 5 weeks after the initial trauma with biomarkers for nutritional status and inflammation. | 29178313 |
| Inflammation, Fracture, Leukocytosis | Altered Intercellular Communication | Fracture healing was associated with initial leukocytosis and a lower thrombocyte count, suggesting that inflammation and thrombocytes are important components in fracture healing. | 29178313 |
| Gonadal Disorders, Adrenal cortical hypofunction | Altered Intercellular Communication | Congenital adrenal insufficiency with 46XY sex reversal is a rare disorder that is characterized by dysregulation of steroid hormone synthesis, leading to adrenal and gonadal dysfunction. | 29178636 |
| Autoimmune Diseases of the Nervous System, Lupus Erythematosus | Altered Intercellular Communication | systemic lupus erythematosus, however, to what extent they are present in autoimmune central nervous system inflammation has not yet been investigated. | 29178933 |
| Airway structure | Altered Intercellular Communication | Eight to ten weeks old BALB/cJ mice were exposed through the airways to particulate material, and markers of airway inflammation were determined. | 29178979 |
| Airway structure, AHR wt Allele | Altered Intercellular Communication | Baltimore PM induced more robust airway inflammation, AHR, and Th2 cytokine production, possibly due to the greater metal content in Baltimore PM. | 29178979 |
| Inflammation | Altered Intercellular Communication | Prognostic significance of procalcitonin might be implicated in inflammation. | 29179592 |
| PROS1 gene, Bone Marrow | Altered Intercellular Communication | This study aims to evaluate thresholding for quantification of subtle bone marrow inflammation in the spine and the sacroiliac (SI) joints of patients with PsA and compare it with the SPARCC scoring system. | 29179748 |
| Inflammation | Altered Intercellular Communication | A threshold was applied to visible bone marrow in order to mask areas with higher signal intensity, which are consistent with inflammation. | 29179748 |
| Hepatitis, Insemination, Artificial, Homologous | Altered Intercellular Communication | Current guidelines have defined biochemical remission (normalisation of biochemical markers for liver inflammation) as a major goal in the treatment of AIH. | 29180000 |
| Inflammation | Altered Intercellular Communication | Sterile inflammation is an immediate and well-coordinated immune response to surgical injury. | 29180192 |
| Inflammation | Altered Intercellular Communication | Induced inflammation stimulates the vagus nerve, which in turn activates anti-inflammatory nonneuronal processes. | 29180192 |
| Inflammation | Altered Intercellular Communication | The spleen is a major organ of the immune system playing an important role during inflammation. | 29180192 |
| Inflammation, Obesity, Diabetes Mellitus | Altered Intercellular Communication | Obesity-induced inflammation engenders insulin resistance and type 2 diabetes mellitus (T2DM) but the inflammatory effectors linking obesity to insulin resistance are incompletely understood. | 29180649 |
| Inflammation | Altered Intercellular Communication | In contrast, more HRDs, which might reflect increased inflammation in the retina, were observed in dexamethasone responders. | 29183041 |
| Trauma, Nervous System | Altered Intercellular Communication | Inflammation-associated and neuronal damage markers were measured in blood and cerebrospinal fluid (CSF) of HIV-infected children aged 8 to 18 years. | 29183044 |
| Trauma, Nervous System | Altered Intercellular Communication | Neuroretinal thinning was associated with inflammation-associated and neuronal injury biomarkers in a cohort of antiretroviral therapy-treated perinatally HIV-infected children. | 29183044 |
| Inflammation, Trauma, Nervous System | Altered Intercellular Communication | These findings suggest that ongoing immune activation, inflammation, and neuronal injury occur in parallel with retinal thinning in pediatric HIV. | 29183044 |
| Inflammatory Bowel Diseases, Gastrointestinal inflammation | Altered Intercellular Communication | Inflammatory bowel disease (IBD) is characterized by chronic inflammation of the gastrointestinal tract that is associated with changes in the gut microbiome. | 29183332 |
| Cholecystitis, Inflammation | Altered Intercellular Communication | We use open cholecystectomy (OC) to treat severe cholecystitis in cases in which we are worried that inflammation might cause anatomical changes in Calot's triangle. | 29183521 |
| Cholecystitis, Fibrosis Assessment, Inflammation | Altered Intercellular Communication | Furthermore, in cases of severe cholecystitis in which marked inflammation leads to fibrosis, we perform subtotal cholecystectomy (SC), i.e., incomplete gallbladder resection. | 29183521 |
| Inflammation, Chronic sinusitis, Craniosynostosis | Altered Intercellular Communication | Chronic rhinosinusitis (CRS) is a heterogeneous disease characterized by epithelial inflammation and tissue eosinophilic infiltration. | 29186722 |
| AUTOIMMUNE DISEASE, MULTISYSTEM, INFANTILE-ONSET, 1, polychondritis, Inflammation | Altered Intercellular Communication | Relapsing polychondritis is a rare multisystem autoimmune disease characterized by recurrent inflammation and destruction of different cartilaginous and proteoglycan-rich structures like cardiovascular system. | 29187087 |
| Inflammation, Carcinogenesis, leukemia | Altered Intercellular Communication | The matrix metalloproteinases (MMPs) are important in inflammation and carcinogenesis, and the genotypic role of MMP7 has never been examined in leukemia to date. | 29187444 |
| Inflammation, Atherosclerosis | Altered Intercellular Communication | Chronic inflammation and activation of the immune system, including B-lymphocyte maturation is believed to play a role in atherosclerosis. | 29189047 |
| Inflammation, Acute infectious disease | Altered Intercellular Communication | recurrent acute infections and low-grade chronic inflammation) on each affected nutrient biomarker. | 29189196 |
| Inflammation, Pain Distress Question | Altered Intercellular Communication | Alarmins in Frozen Shoulder: A Molecular Association Between Inflammation and Pain. | 29190116 |
| Inflammation | Altered Intercellular Communication | Ultra-wide-field fluorescence angiography (UWFA) was conducted on 13 patients, and peripheral vascular leakage was observed in 22/26 eyes (84.62%) compared with active anterior chamber inflammation in 13/26 eyes (50%). | 29190160 |
| Inflammation, Bipolar Disorder | Altered Intercellular Communication | The association between depressive symptoms and insulin resistance, inflammation and adiposity in men and women. | 29190710 |
| Inflammation, Depression, CTCAE | Altered Intercellular Communication | Depression has been shown to be associated with elevated leptin levels, low-grade inflammation and insulin resistance. | 29190710 |
| Inflammation, Depressed mood, Diabetes Mellitus | Altered Intercellular Communication | A cross-sectional analysis was carried out on a cohort of 639 participants from the ADDITION-Leicester dataset to assess differences in markers of diabetes risk, cardiovascular risk and inflammation in depressed and non-depressed individuals. | 29190710 |
| Inflammation, Atherosclerosis | Altered Intercellular Communication | Elevated oxidized low-density lipoprotein (ox-LDL) and cell adhesion molecules are associated with inflammation and atherosclerosis. | 29190851 |
| Inflammation, Nerve Degeneration | Altered Intercellular Communication | JEV is associated with neurodegeneration, severe inflammation, increased oxidative stress and elevated levels of stress linked proteins. | 29191708 |
| Symptoms, Inflammation, Blood Vessel | Altered Intercellular Communication | The primary endpoint was time to relapse of TAK, defined as >=2 of the following: objective systemic symptoms, subjective systemic symptoms, elevated inflammation markers, vascular signs and symptoms or ischaemic symptoms. | 29191819 |
| Intrahepatic Cholangiocarcinoma | Altered Intercellular Communication | Prognostic Implication of Inflammation-based Prognostic Scores in Patients with Intrahepatic Cholangiocarcinoma Treated with First-line Gemcitabine plus Cisplatin. | 29192354 |
| Gastrointestinal inflammation | Altered Intercellular Communication | Fecal calprotectin (FC) is a marker of intestinal inflammation. | 29192504 |
| Intraepithelial Lymphocytes, Inflammation, Graft-vs-Host Disease, Bile duct structure, Damage, Cholestasis | Altered Intercellular Communication | Two hepatopathologists blindly evaluated 40 liver biopsies from patients with clinically and biologically confirmed graft-versus-host disease, as well as 44 controls, for percent bile duct loss, bile duct damage, intraepithelial lymphocytes, ductular reaction, acidophilic bodies/10 high power fields (HPF), cholestasis, portal and lobular inflammation, and endotheliitis. | 29192646 |
| Acute and chronic inflammation | Altered Intercellular Communication | A final histopathological diagnosis of ectopic brain tissue with neural tissue demonstrating focal, chronic T-cell inflammation was made. | 29192861 |
| Communicable Diseases, Inflammation | Altered Intercellular Communication | A distinct mechanism of senescence activation in amnion epithelial cells by infection, inflammation, and oxidative stress. | 29193446 |
| Communicable Diseases, Tumor necrosis, Inflammation | Altered Intercellular Communication | We investigated p38MAPK activation-induced fetal membrane cell senescence in response to inflammation (tumour necrosis factor-alpha [TNF-a]) and infection (lipopolysaccharide [LPS]), factors associated with spontaneous preterm birth. | 29193446 |
| Hepatic inflammation, Alcoholic Liver Diseases | Altered Intercellular Communication | Hepatic inflammation, triggered by activated Kupffer cells, is a driving force in alcoholic liver disease. | 29193575 |
| Inflammation, Injury of liver, Alcoholic Liver Diseases | Altered Intercellular Communication | Interleukin 37 transgenic mice are not protected against hepatic injury and inflammation in alcoholic liver disease. | 29193575 |
| Hepatic inflammation, Alcoholic Liver Diseases | Altered Intercellular Communication | Human recombinant Interleukin 37 ameliorated hepatic inflammation in a binge drinking model of alcoholic liver disease. | 29193575 |
| Inflammatory, Chronic sinusitis, Craniosynostosis, Olfactory Receptor Cells | Altered Intercellular Communication | Olfactory inflammation in chronic rhinosinusitis (CRS) is associated with cytokines that may result in the death of olfactory sensory neurons. | 29193850 |
| Acute and chronic inflammation | Altered Intercellular Communication | Activation of neuronal JNK is a feature of chronic olfactory inflammation that is associated with neuronal apoptosis. | 29193850 |
| Inflammation, ASAH1 gene | Altered Intercellular Communication | Both cellular and molecular (cytokines) inflammation play a key role after aSAH during the phase of occurrence of post-SAH complications. | 29194369 |
| Inflammation, Depression, CTCAE, Oral pain, Pain Distress Question | Altered Intercellular Communication | Considering that inflammation is associated with the pathophysiology of BMS, and that inflammation is closely associated with pain and depression, we aimed to correlate depressive symptomatology and oral cavity pain with plasma cytokine/chemokine signatures in a cohort of patients with BMS. | 29194773 |
| Inflammation, Neoplasms | Altered Intercellular Communication | This offers two potential pathways that may facilitate tumour progression - local inflammation promoting peritoneal adherence and implantation, and secondary suppression of immunosurveillance due to circulating inflammatory response. | 29194906 |
| Inflammation, Ischemic stroke, Cerebrovascular accident | Altered Intercellular Communication | Background Procarboxypeptidase U (proCPU, TAFI, proCPB2), the zymogen of CPU, which is a potent antifibrinolytic enzyme and a modulator of inflammation, has previously been investigated in plasma of stroke patients, but so far, no information on the proCPU levels in cerebrospinal fluid (CSF) during acute ischemic stroke (AIS) is available. | 29194929 |
| Inflammation, Pain Distress Question, palladium, Fibrosis Assessment, Peyronie Disease, Connective Tissue Diseases | Altered Intercellular Communication | Peyronie's disease (PD) is an acquired connective tissue disorder of the tunica albuginea with fibrosis and inflammation that lead to palpable plaques formation, penile curvature, and pain during erection. | 29195031 |
| Inflammation, Autonomic neuropathy, Canada | Altered Intercellular Communication | Biomarkers of inflammation and adiponectin are associated with cardiovascular autonomic neuropathy (CAN) in cross-sectional studies, but prospective data are scarce. | 29195493 |
| Inflammation, Neurogenic arthropathy, Diabetes Mellitus | Altered Intercellular Communication | Bone mineral density and markers of bone turnover and inflammation in diabetes patients with or without a Charcot foot: An 8.5-year prospective case-control study. | 29196119 |
| Inflammation, Hemorrhagic, COL4A2 wt Allele, Brain hemorrhage | Altered Intercellular Communication | Higher S100A12 concentrations are positively associated with inflammation, hemorrhagic severity and short-term mortality among ICH patients, indicating S100A12 may represent a biomarker for predicting poor outcome after hemorrhagic stroke. | 29196185 |
| Pain Distress Question, Inflammation, Depression, CTCAE | Altered Intercellular Communication | Opioid usage was more likely to be associated with subjective measures (depression, BASDAI, BASFI) than objective measures (CRP, ESR), suggesting that pain in AS may derive from sources other than spinal inflammation alone. | 29196383 |
| Erectile dysfunction, Tuberculosis, Atherosclerosis | Altered Intercellular Communication | No previous studies have investigated the prevalence of latent tuberculosis infection (LTBI) among patients with erectile dysfunction (ED) or its contribution to the development of high-grade ED through a process of chronic inflammation-induced atherosclerosis. | 29196694 |
| Inflammation, Aggressive behavior, Obesity, Visceral | Altered Intercellular Communication | Visceral obesity is considered to be associated not only with chronic systemic inflammation but also with aggressive cancer behavior. | 29196841 |
| Inflammation, Atherosclerosis | Altered Intercellular Communication | Lipoxygenases (LOXs) and their genes are of critical importance in oxidative stress, inflammation, and atherosclerosis. | 29196930 |
| Inflammation, Depression, CTCAE | Altered Intercellular Communication | Whilst there is evidence of an association between depression and inflammation in adults, there is limited data on this in adolescents particularly in non-westernized populations. | 29197794 |
| Inflammation, Depression, CTCAE | Altered Intercellular Communication | The cross sectional study design does not allow us to conclude that there is a direct relationship between inflammation and depression, and this would need to be tested in an intervention study. | 29197794 |
| Inflammation, Ischemic stroke | Altered Intercellular Communication | Exposure to cadmium has been associated with carotid plaques, inflammation in carotid plaques, and increased risk of ischemic stroke. | 29197829 |
| Inflammation, Congestive heart failure | Altered Intercellular Communication | At the same time, anti-inflammatory cytokines such as IL-10 may neutralize inflammation in CHF. | 29198133 |
| Inflammation, FOXP3 gene, Congestive heart failure | Altered Intercellular Communication | Although inflammation plays a central role in the pathophysiology of CHF, the roles of FOXp3, RORgt, and IL-10 remain to be determined (Tab. | 29198133 |
| Communicable Diseases, Oligospermia | Altered Intercellular Communication | After excluding viral, infectious, genetic and anatomical causes of the subject's oligoasthenoteratozoospermia, we performed a hormonal analysis to verify our hypothesis. | 29198592 |
| Cessation of life, Inflammation | Altered Intercellular Communication | However, little is known about systemic inflammation in kidney donors and, notably, brain death causes a strong systemic inflammatory response. | 29198657 |
| Inflammation, Oral lesion | Altered Intercellular Communication | One individual demonstrated reduction in palatal inflammation and another one did not show improvement in the oral lesion. | 29198763 |
| Candidemia, Inflammation | Altered Intercellular Communication | Chemokine CXCL13 is well-known involved in inflammation, but its role in candidemia has not been assessed. | 29198822 |
| Inflammation, Rheumatoid Arthritis, Disease | Altered Intercellular Communication | Remaining local subclinical joint inflammation is associated with deteriorated metacarpeal head bone microarchitecture in rheumatoid arthritis patients low disease activity. | 29198886 |
| Inflammation | Altered Intercellular Communication | They were divided in two groups according to local inflammation assessed by Doppler-ultrasound exam surrounding the site of erosion. | 29198886 |
| Refractory anemias, Inflammation, Disease | Altered Intercellular Communication | In RA patients in low disease activity under bDMARDs, persistence of local inflammation was associated with alteration of the trabecular compartment. | 29198886 |
| Data types - Address, physiopathological | Altered Intercellular Communication | The time course of altered synaptic transmission mimics the spread of pathology through hippocampus in human AD and provides support for this model as a valuable preclinical tool in elucidating pathological mechanisms of early synapse dysfunction in AD. | 29199135 |
| Inflammation, Arthritis, Infectious, septic | Altered Intercellular Communication | Wrist inflammation: a retrospective comparison between septic and non-septic arthritis. | 29199508 |
| Inflammation, Arthritis, Infectious | Altered Intercellular Communication | This study aims to identify differences in demographics, clinical and laboratory data between wrist septic arthritis and non-septic arthritis in patients admitted for wrist inflammation. | 29199508 |
| Inflammation, Arthritis, Infectious | Altered Intercellular Communication | In patients with isolated wrist inflammation, the mean C-reactive protein in the septic arthritis group was significantly higher compared with the non-septic arthritis group (mean difference 132 mg/L, 95% CI 30.9-234). | 29199508 |
| Inflammation, Impaired cognition, "Alzheimers Disease | Altered Intercellular Communication | Inflammation has been linked to clinical cognitive impairment, including Alzheimer's disease. | 29199872 |
| Inflammation | Altered Intercellular Communication | Less is known, however, about the relationship between inflammation and normal, age-associated cognitive decline. | 29199872 |
| Inflammation | Altered Intercellular Communication | This study investigated whether biomarkers of inflammation were associated with cognitive function and decline in older Taiwanese adults. | 29199872 |
| Inflammation, Impaired cognition | Altered Intercellular Communication | This study did not support a causal link between inflammation and cognitive decline among this older cohort. | 29199872 |
| Refractory anemias, Rheumatoid Arthritis, Inflammation, Inflammatory disorder | Altered Intercellular Communication | Rheumatoid arthritis (RA) is a systemic inflammatory disease that causes chronic inflammation of the joints. | 29200952 |
| Inflammation | Altered Intercellular Communication | Structured reporting for tubular inflammation showed excellent agreement (kappa = 1), but no other subdomain demonstrated better than moderate agreement (kappa < 0.6). | 29202260 |
| Post-Traumatic Stress Disorder, Inflammation | Altered Intercellular Communication | Inflammation has been hypothesised to be a link between PTSD and the most common co-morbid medical disorders. | 29202383 |
| Post-Traumatic Stress Disorder, Inflammation | Altered Intercellular Communication | However, the relationship between inflammation and PTSD is not clear. | 29202383 |
| Inflammation, Fibrosis Assessment | Altered Intercellular Communication | Angiotensin-converting enzyme defines matrikine-regulated inflammation and fibrosis. | 29202450 |
| Inflammation | Altered Intercellular Communication | Pulmonary ACE is elevated during episodes of acute inflammation, as a consequence of enhanced vascular permeability, to ensure the efficient degradation of AcPGP. | 29202450 |
| ARCN1 gene, Inflammation, Fibrosis Assessment, Idiopathic Pulmonary Fibrosis | Altered Intercellular Communication | Thus, AcPGP seemingly has very divergent roles: it is pathogenic in its capacity to drive neutrophilic inflammation and matrix degradation in the context of COPD, but it is protective in its capacity to limit fibrosis in IPF. | 29202450 |
| Inflammation, Postexertional fatigue, Anxiety, CTCAE 3.0, Depression, CTCAE, Fatigue | Altered Intercellular Communication | Clinical markers consisted of questionnaire scores for symptoms of post-exertional malaise, inflammation, fatigue, depression and trait anxiety, as well as activity recordings. | 29202780 |
| Inflammation, Asthma | Altered Intercellular Communication | In this community based population, non-eosinophilic asthma was common, less severe than EA, and at baseline most asthmatics showed no evidence of inflammation. | 29202821 |
| Mycosis Fungoides, Inflammation, Venous Thromboembolism, vinyltriethoxysilane | Altered Intercellular Communication | Mycosis fungoides (MF) and parapsoriasis are characterized by malignant proliferation and chronic inflammation, which may affect the risk for venous thromboembolism (VTE). | 29203438 |
| Proctitis | Altered Intercellular Communication | Metronidazole improved her abdominal symptoms, as well as her colonoscopic and histopathological findings, suggesting that HIS was responsible for her colorectal inflammation. | 29204849 |
| Inflammation, Kidney Diseases, diabetic | Altered Intercellular Communication | Inflammation plays a key role in DN, and pentosan polysulfate (PPS) has been shown to largely attenuate the inflammation of nephropathy in aging diabetic mice. | 29207166 |
| Inflammation, Hyperglycemia | Altered Intercellular Communication | p38 mitogen-activated protein kinase (p38 MAPK) plays a crucial role in tissue inflammation and cell apoptosis, and it is activated by hyperglycemia. | 29207166 |
| Inflammation | Altered Intercellular Communication | Distinct Roles of Endothelial Dysfunction and Inflammation in Intracranial Atherosclerotic Stroke. | 29207392 |
| Inflammation, Endothelial dysfunction | Altered Intercellular Communication | Markers of endothelial dysfunction (asymmetric dimethylarginine, ADMA) and inflammation (lipoprotein-associated phospholipase A2, Lp-PLA2) were measured. | 29207392 |
| Inflammation, Acute infarct, Endothelial dysfunction | Altered Intercellular Communication | Endothelial dysfunction and inflammation have distinct effects in ICAS patents; endothelial dysfunction is associated with the underlying micro- and macro-atherosclerotic burden, whereas inflammation is associated with acute infarct volume and pattern. | 29207392 |
| Pancreatic Diseases, Inflammation | Altered Intercellular Communication | Recent studies indicate that the sphingolipid signaling pathway may be one of the important factors contributing to the development of inflammation in pancreatic diseases. | 29207545 |
| Cytomegalovirus Infections, Inflammation, Epithelial | Altered Intercellular Communication | The remarkable histological feature of CMV infection appeared to be significant acute inflammation in addition to apoptotic epithelial injuries, and particularly in an early stage of CMV replication, acute inflammation is possibly the only detectable feature of CMV infection. | 29207904 |
| Retinitis | Altered Intercellular Communication | Fluorescein angiography (FA) showed nonspecific retinal inflammation, and an electroretinogram (ERG) illustrated decreased amplitude of the b wave in both eyes. | 29207977 |
| Barrett Esophagus, Inflammation, Esophagitis, Esophageal carcinoma | Altered Intercellular Communication | Considerable evidence supports a major role for chronic inflammation and diverse chemokine pathways in the development of Barrett's esophagus and esophageal adenocarcinoma.Experimental Design: Here we utilized an IL1b transgenic mouse model of Barrett's esophagus and esophageal adenocarcinoma and human patient imaging to analyze the importance of CXCR4-expressing cells during esophageal carcinogenesis.Results: IL1b overexpression induces chronic esophageal inflammation and recapitulates the progression to Barrett's esophagus and esophageal adenocarcinoma. | 29208671 |
| Inflammation, Infection caused by Helicobacter pylori, Eyelid Xanthoma, Carcinogenesis, physiopathological | Altered Intercellular Communication | Current study described a large xanthelasma cohort in Chinese population, revealed its relationship with H. pylori infection, carcinogenesis, metabolic dysfunction and inflammation as well. | 29209116 |
| Inflammation, Histoplasmosis | Altered Intercellular Communication | Post-mortem examination revealed that her ileo-colonic inflammation was caused by Histoplasmosis. | 29209121 |
| Inflammation, Diarrhea, Ulcerative Colitis | Altered Intercellular Communication | Ulcerative colitis (UC) is a chronic inflammation of the large bowel characterized by diarrhea and a negative stool culture. | 29211811 |
| FTO protein, human, Obesity | Altered Intercellular Communication | FeNO might help to identify patients with eosinophilic inflammation-driven asthma, whereas patients with low FeNO might have an obesity-associated asthma phenotype in which symptoms are partly caused by the obesity. | 29212496 |
| Respiratory Distress Syndrome, Adult, Inflammation, Respiratory Distress Syndrome, Newborn | Altered Intercellular Communication | Sepsis-associated acute respiratory distress syndrome (ARDS) is characterized by neutrophilic inflammation and poor survival. | 29212955 |
| Inflammation, Congenital bilateral aplasia of vas deferens | Altered Intercellular Communication | In our present work, complex connections among mechano-response, oxidative stress, inflammation and extracellular remodeling pathways in the etiology of CAVD were revealed. | 29212967 |
| vascular inflammations | Altered Intercellular Communication | The total vascular inflammation score (TVIS), angiogenesis score (AS), and numbers of VEGF-expressing and TNF-a-expressing cells were analyzed in the fascia and muscle. | 29216907 |
| Inflammation | Altered Intercellular Communication | The fascia can therefore be a primary site of inflammation and angiogenesis in the pathogenesis of DM. | 29216907 |
| Refractory anemias, Inflammation, Destruction of tissue | Altered Intercellular Communication | In the course of RA, the BM microenvironment can promote the development of Th17 cell responses and overproduction of IL-17AF that may lead to increased inflammation and tissue destruction in RA BM. | 29216915 |
| Congenital leptin deficiency, Hyperphagia, Obesity | Altered Intercellular Communication | The most common of the single gene alterations affect the leptin gene (LEP), resulting in congenital leptin deficiency that manifests as intense hyperphagia, EOO and severe obesity associated with hormonal and metabolic alterations. | 29217499 |
| Inflammation, Hyphema | Altered Intercellular Communication | There were no complications including hyphema, peripheral anterior synechia formation nor prolonged inflammation throughout the follow-up period. | 29218423 |
| Inflammation, Lesion of cervix | Altered Intercellular Communication | Due to the accompanying and often obscuring lymphocytic inflammation, malignant cells may be difficult to recognize on cytologic samples and can mimic several more common benign and atypical cervical lesions. | 29218797 |
| Inflammation, Periodontitis, Non-alcoholic Fatty Liver Disease, Diabetes Mellitus | Altered Intercellular Communication | NAFLD, periodontitis and diabetes share common risk factors, are characterised by inflammation and associated with changes in commensal bacteria. | 29220367 |
| Nephritis, Chronic Kidney Diseases | Altered Intercellular Communication | Total flavones extracted from Abelmoschus manihot L. (Malvaceae) medic (TFA) have been proven clinically effective at improving renal inflammation and glomerular injury in chronic kidney disease (CKD). | 29221422 |
| Nephritis | Altered Intercellular Communication | Our results show that TFA could dose-dependently ameliorate renal inflammation by inhibiting the activation of iRhom2/TACE signalling and attenuating ER stress. | 29221422 |
| Inflammation | Altered Intercellular Communication | d-Deprenyl when used as a positron emission tomography tracer visualizes peripheral inflammation. | 29221756 |
| Inflammation, Hypertension, CTCAE, Diabetes Mellitus, Non-Insulin-Dependent | Altered Intercellular Communication | Inflammation in the Prediction of Type 2 Diabetes and Hypertension in Healthy Adults. | 29221802 |
| Inflammation, Hypertension, CTCAE, Diabetes Mellitus, Non-Insulin-Dependent, Obesity | Altered Intercellular Communication | While inflammation is associated with obesity and insulin resistance, their inter-relationships in the development of type 2 diabetes or hypertension are not clear. | 29221802 |
| Vasculitis, Axonal degeneration | Altered Intercellular Communication | Nerve biopsies (n = 2) showed microvascular inflammation with axonal degeneration. | 29222126 |
| Dermatitis, Atopic, Data types - Address, Dermatitis, Pain of skin, Pruritus | Altered Intercellular Communication | Atopic dermatitis (AD) is associated with itch, skin inflammation and barrier disruption, and scratching, all of which may be associated with skin pain. | 29223299 |
| Inflammation, Diabetes Mellitus | Altered Intercellular Communication | Low-grade systemic inflammation: a partial mediator of the relationship between diabetes and lung function. | 29223510 |
| Inflammation, Diabetes Mellitus | Altered Intercellular Communication | Our results suggest that low-grade systemic inflammation could only explain a small part of the relationship between diabetes and lung function. | 29223510 |
| Inflammation, Impaired cognition, Nerve Degeneration | Altered Intercellular Communication | Chronic low-grade inflammation during aging (inflammaging) is associated with cognitive decline and neurodegeneration; however, the mechanisms underlying inflammaging are unclear. | 29223680 |
| Inflammation, Impaired cognition, Nerve Degeneration | Altered Intercellular Communication | Chronic low-grade inflammation during aging (inflammaging) is associated with cognitive decline and neurodegeneration; however, the mechanisms underlying inflammaging are unclear. | 29223680 |
| Inflammation | Altered Intercellular Communication | These findings support the association of peripheral inflammation, as demonstrated by CXCL10, in aging and cognitive decline. | 29223680 |
| vascular inflammations, Lipid Metabolism Disorders | Altered Intercellular Communication | Available data supports the conclusion that e-waste-exposed children with higher BPbs and concomitant abnormal measures of cardiovascular physiology have an augmented prevalence of vascular inflammation, as well as lipid disorder. | 29223817 |
| Inflammation, Kidney Failure, Acute, Endothelial dysfunction | Altered Intercellular Communication | Inflammation, oxidative stress, and endothelial dysfunction and damage play important roles in the development of AKI. | 29223955 |
| Otosclerosis, Inflammation, Paget Disease | Altered Intercellular Communication | Microcavitations found in periosteal and endosteal layers of human temporal bone specimens without otosclerosis, Paget's disease, or inflammation as reported in the current study are consistent with osteoclastic bone resorption. | 29224005 |
| Inflammation, Deficiency of butyryl-CoA dehydrogenase, Affection | Altered Intercellular Communication | Our findings first strengthen the hypothesis that inflammation critically impacts on the occurrence of sCAD, and second linked this condition with a marked affection of the coagulation system. | 29224120 |
| Thrombophilia, Familial cervical artery dissection | Altered Intercellular Communication | Spontaneous cervical artery dissection is accompanied by a hypercoagulable state and simultaneous inflammatory condition. | 29224120 |
| Inflammation, Hemorrhage, diabetic | Altered Intercellular Communication | Furthermore, we observed a reduction of spontaneous central bleeding and inflammation after PP treatment in diabetic mice. | 29224179 |
| Multiple Endocrine Neoplasia, Hyperparathyroidism, Primary, Menin | Altered Intercellular Communication | Primary hyperparathyroidism is the most common hormonal manifestation associated with multiple endocrine neoplasia 1 (MEN1). | 29225207 |
| Inflammatory Bowel Diseases, Inflammation, Malnutrition, Anemia | Altered Intercellular Communication | The aim of this study was to test hypothesis that transferrin, coinfluenced by inflammation, malnutrition, anemia, and oxidative stress, may better reflect global IBD patient's condition than any other more specific index. | 29226154 |
| Inflammatory Bowel Diseases, Inflammation, Malnutrition, Ulcerative Colitis, Anemia, Crohn Disease | Altered Intercellular Communication | Transferrin and other indices of inflammation, anemia, malnutrition, and oxidative stress were measured in 137 IBD patients (Crohn's disease (CD): n = 63 and ulcerative colitis (UC): n = 74) and 97 controls. | 29226154 |
| Inflammation, Ulcerative Colitis | Altered Intercellular Communication | The associations with inflammation and anemia/malnutrition were more pronounced in UC and with oxidative stress in CD. | 29226154 |
| Inflammation | Altered Intercellular Communication | This result confirmed that periodontal inflammation might be a contributive factor of MetS. | 29226321 |
| Inflammation, Malnutrition | Altered Intercellular Communication | Eventually, our study associates low hArg concentrations with chronic low-grade inflammation and parameters of malnutrition in cardiovascular high-risk patients. | 29226642 |
| Refractory anemias, Rheumatoid Arthritis, Autoimmune Diseases, Inflammation | Altered Intercellular Communication | Rheumatoid arthritis (RA) is an autoimmune disease characterized by inflammation and pro-inflammatory cytokines production. | 29226727 |
| Acute inflammation, Platelet aggregation test result | Altered Intercellular Communication | These data demonstrate a novel dynamic variation in platelet aggregation with acute vascular inflammation, including AA-induced whole blood clotting which is apparently COX-1 independent. | 29227173 |
| Inflammation | Altered Intercellular Communication | Oxidative stress from cigarette smoke and chronic inflammation is likely to induce this corticosteroid insensitivity. | 29227717 |
| Arthritis, Psoriasis | Altered Intercellular Communication | Circulating IFNg-producing CD8+ T-cells are raised in PsA when compared to psoriasis, suggesting a potential pathogenetic involvement of CD8+ T-cells and IFNg production in chronic joint inflammation and damage. | 29228429 |
| Inflammation, Tuberculosis, Necrosis | Altered Intercellular Communication | 23% were known cases of tuberculosis with some cytological findings including inflammation, necrotic calcified deposits, multinucleated giant cell and reserve cell hyperplasia. | 29228529 |
| Inflammation, Basal cell hyperplasia | Altered Intercellular Communication | 19% were pneumonic patients with smears demonstrating inflammation, curschmann's spiral and reserve cell hyperplasia. | 29228529 |
| Lupus Erythematosus, Systemic, Granulomatous inflammation, Sarcoidosis, Hydatid cyst (organism), Rheumatoid Arthritis, Lung Diseases, Interstitial, Chronic kidney disease stage 5, Heart failure, Asthma | Altered Intercellular Communication | Other non-neoplastic cases included in this study were asthma, granulomatous inflammation, rheumatoid arthritis, sarcoidosis, Wegener, SLE, heart failure, hydatid cyst, interstitial lung disease, and end stage renal disease. | 29228529 |
| Tissue damage, Inflammation | Altered Intercellular Communication | Collectively, our findings imply that NOX4 mediates ROS production in radiation-induced senescent cells and contributes to normal tissue damage after IR via the recruitment of inflammatory cells and the exacerbation of tissue inflammation. | 29228832 |
| Inflammation, Metallosis, Pseudotumor, Necrosis, Periprosthetic Fractures | Altered Intercellular Communication | ARMD consists of a wide range of alterations in periprosthetic tissues, most important of which are metallosis, inflammation, pseudotumors and necrosis. | 29228956 |
| Inflammation, Diego blood group system | Altered Intercellular Communication | Gradual spreading of inflammation to the infundibulum after RCC removal was considered as 1 possible mechanism of this delayed DI development. | 29229338 |
| Fibrosis Assessment, Hepatitis | Altered Intercellular Communication | Plasma cfDNA levels were associated with the degree of liver inflammation, body mass index, and alpha-fetoprotein (AFP) level, but were not associated with fibrosis stages. | 29229500 |
| Degenerative polyarthritis, Inflammation | Altered Intercellular Communication | Chronic inflammation in OA is a relevant factor in the development of cellular senescence and joint degradation. | 29230269 |
| Inflammation, Alcohol abuse | Altered Intercellular Communication | Elevated inflammation in association with alcohol abuse among Blacks but not Whites: results from the MIDUS biomarker study. | 29230616 |
| Inflammation, selenium, Alcohol abuse | Altered Intercellular Communication | Race moderated the association between alcohol abuse and CRP (b = 0.56, SE = 0.28, p = 0.048), IL-6 (b = 0.65, SE = 0.22, p = 0.004), and a composite inflammation score (b = 0.014, SE = 0.07, p = 0.041). | 29230616 |
| Inflammation, Obesity | Altered Intercellular Communication | This finding underlines the role that obesity plays in inflammation and autoimmune conditions. | 29231278 |
| Inflammation, Bladder Neoplasm | Altered Intercellular Communication | The bladder wall may thicken resulting from chronic inflammation after initial treatment (transurethral resection [TUR] or neoadjuvant chemotherapy), which may mimic the feature of recurrent or residual bladder tumors (RBT). | 29232021 |
| Inflammation, Fibrosis Assessment | Altered Intercellular Communication | Syndecan-4 is a transmembrane glycoprotein associated with inflammation and fibrosis. | 29232393 |
| Arterial Stiffness, Inflammation, Lupus Erythematosus | Altered Intercellular Communication | Association of Resting Heart Rate With Arterial Stiffness and Low-Grade Inflammation in Women With Systemic Lupus Erythematosus. | 29232972 |
| Arterial Stiffness, Inflammation | Altered Intercellular Communication | Resting heart rate (RHR) is associated with arterial stiffness, inflammation, and cardiovascular (CV) and all-cause mortality in the general population and in patients at high CV risk. | 29232972 |
| Inflammation, Adverse event, Atherosclerosis | Altered Intercellular Communication | Epicardial adipose tissue density and volume are related to subclinical atherosclerosis, inflammation and major adverse cardiac events in asymptomatic subjects. | 29233634 |
| Inflammation, Calcification of coronary artery, Dental Plaque, Eating | Altered Intercellular Communication | Lower EAT density and increased EAT volume were associated with coronary calcification, serum levels of plaque inflammatory markers and MACE, suggesting that dysfunctional EAT may be linked to early plaque formation and inflammation. | 29233634 |
| Refractory anemias | Altered Intercellular Communication | Such US features may have low specificity in inflammatory conditions affecting joints and enthesis such as SpA and RA. | 29233691 |
| Inflammation, Odontogenic Cysts | Altered Intercellular Communication | The diagnostic process can sometimes be hindered by tissue inflammation of KCOTs with loss of defining criteria, resulting in misdiagnosis as an odontogenic jaw cyst. | 29233700 |
| Nephritis | Altered Intercellular Communication | In biopsy tissues, CD147 induction was detected in injured lesions representing renal inflammation. | 29234893 |
| HSP90AA1 wt Allele, Nephritis, IGA Glomerulonephritis | Altered Intercellular Communication | Plasma CD147 values correlated with eGFR in patients with inflammation-related kidney diseases such as IgAN, HSPN, and DKD. | 29234893 |
| Inflammation, Cardiac Arrhythmia, Tachycardia, Ventricular | Altered Intercellular Communication | During a 6-week postablation "blanking period" (when arrhythmias may occur owing to postablation inflammation), there were 680 episodes of ventricular tachycardia. | 29236642 |
| Contusions, Glossitis | Altered Intercellular Communication | In addition, itching, dry skin, easy bruising, pigmentation, papulopustules on face, periungual inflammation, nail changes, and palmoplantar lesions were associated with significantly higher DLQI scores. | 29237254 |
| Glossitis | Altered Intercellular Communication | Periungual inflammation and palmoplantar lesions scored the highest DLQI. | 29237254 |
| Inflammation, Lung Injury | Altered Intercellular Communication | In various animal models of lung injury, HA has been shown to play a mechanistic role in modulating inflammation and injury. | 29237497 |
| Polymyositis, Inflammation | Altered Intercellular Communication | Roles of macrophage migration inhibitory factor in polymyositis: Inflammation and regeneration. | 29239244 |
| Inflammation, Polymyositis | Altered Intercellular Communication | Conclusion MIF and IL-6 play important roles in the inflammation associated with polymyositis. | 29239244 |
| Asthma | Altered Intercellular Communication | This may indicate that age may contribute to pulmonary function impairment in asthmatic women independently of their hormonal status at the time of asthma diagnosis. | 29240514 |
| Inflammation, Dental Plaque | Altered Intercellular Communication | In all cases, inflammation was most severe in the upper two-thirds of the dermis, and the differences in pustulopapular and plaque lesions were more prominent in the peri-inflammation area. | 29240822 |
| Inflammation, Anemia, Chronic Kidney Diseases | Altered Intercellular Communication | The pathogenesis of chronic kidney disease associated anemia is multifactorial and includes decreased production of erythropoietin (EPO), iron deficiency, inflammation, and EPO resistance. | 29241199 |
| Inflammation, atherosclerotic, Atherosclerosis | Altered Intercellular Communication | The Neutrophil-to-Lymphocyte Ratio (NLR), an index of systemic inflammation, has been reported to be associated with subclinical atherosclerosis, but its predictive role of the presence of carotid atherosclerotic plaques remains undefined. | 29241668 |
| Communicable Diseases, Inflammation, Traumatic injury, Inflammatory disorder | Altered Intercellular Communication | The Eph/ephrin receptor ligand system is known to play a role in inflammation induced by infection, injury, and inflammatory diseases. | 29242524 |
| Eosinophilic disorder, IgG4-Related Sclerosing Disease | Altered Intercellular Communication | IgG4-related disease (IgG4-RD) is a rare fibro-inflammatory condition that can affect almost any organ, characterized by tumefactive lesions and often by eosinophilia and elevated serum IgG4 concentrations. | 29243036 |
| Inflammation, Rheumatoid Arthritis | Altered Intercellular Communication | Association between urinary sodium and potassium excretion and blood pressure and inflammation in patients with rheumatoid arthritis. | 29243056 |
| Refractory anemias, Inflammation | Altered Intercellular Communication | Patients with RA have many comorbidities associated with salt sensitivity, but their salt intake and its relationship to blood pressure and inflammation is unknown. | 29243056 |
| Autistic behavior, Inflammation, Electrocardiogram: myocardial infarction (finding), Post-Traumatic Stress Disorder | Altered Intercellular Communication | Background Myocardial infarction-triggered acute stress disorder (ASD) and subclinical inflammation associate with the development of posttraumatic stress disorder, and worsen the prognosis of myocardial infarction patients. | 29243511 |
| Inflammation, fibrogenesis | Altered Intercellular Communication | Galectin-3 (Gal-3), a biomarker of inflammation, tissue repair and fibrogenesis, is associated to left ventricular remodeling after ST-elevated myocardial infarction (STEMI), but its relation with long-term outcomes is unclear. | 29243525 |
| Inflammation, Neoplasms | Altered Intercellular Communication | Tumor was reported to correlate with inflammation and the host's inflammatory response to tumor has been shown to independently predict the outcome. | 29243802 |
| Inflammation, Allergy - Charge Type Reason | Altered Intercellular Communication | MDT prepared the wound bed to receive skin autograft, successfully, without any interaction, allergy, or inflammation. | 29244970 |
| Communicable Diseases, Inflammation | Altered Intercellular Communication | But we can learn that foreign body should be one of consideration for the origin of inflammation or infection of soft tissues even there is not any laceration and penetration injuries. | 29245255 |
| SLC26A5 gene, Inflammation, Hemorrhage | Altered Intercellular Communication | PRES may be related to postpartum hemorrhage, blood pressure fluctuation, inflammation, and contrast agents. | 29245268 |
| Aggressive course, Inflammation, Behcet Syndrome, In-Stent Restenosis Indicator | Altered Intercellular Communication | Coronary artery involvement of Behcet disease warrants more attention and investigation; repeated in-stent stenosis, aggressive progress, and elevated inflammation markers should be regard with more care earlier in clinical practice. | 29245339 |
| Inflammation, Arterial aneurysm, Depression, CTCAE | Altered Intercellular Communication | After a 3-month treatment, follow-up examination showed a depression of the inflammation and a slight decrease of the arterial aneurysms. | 29245353 |
| Inflammation, Sleep Apnea, Obstructive | Altered Intercellular Communication | Finally, we arrived at a conclusion that serum d-lactate was increased in nonobese middle-aged males with obstrutive sleep apnea, possibly suggesting existence of subclinical disruption of intestinal barrier, and showed significant associations with inflammatory mediators, possibly being involved in systemic inflammation of obstructive sleep apnea. | 29245360 |
| Inflammation, Communicable Diseases, Herpes Simplex Infections, Chlamydia trachomatis, Lesion of cervix | Altered Intercellular Communication | Some sexually transmitted infectious agents, such as Chlamydia trachomatis and Herpes simplex, cause local inflammation, and could contribute to Human Papillomavirus (HPV) and cervical lesion progression. | 29246195 |
| Infarction, Myocarditis, Traumatic injury | Altered Intercellular Communication | Myocardial inflammation, injury and infarction during on-pump coronary artery bypass graft surgery. | 29246240 |
| Myocarditis | Altered Intercellular Communication | Myocardial inflammation and injury occur during coronary artery bypass graft (CABG) surgery. | 29246240 |
| Joint Task Force Type 1 Myocardial Infarction, Myocarditis | Altered Intercellular Communication | USPIO-defined cellular myocardial inflammation ranged from normal to those associated with type 1 myocardial infarction (median 80.2 [IQR 67.4 to 104.8] /s). | 29246240 |
| Inflammation, Myocarditis | Altered Intercellular Communication | LGE was associated with the delayed 24-h peak in hs-cTnI and its magnitude correlated with AUC plasma hs-cTnI concentrations (r = 0.33, p < 0.01) but not systemic inflammation, myocardial inflammation or bypass time. | 29246240 |
| Airway structure, Pulmonary function tests, Cystic Fibrosis | Altered Intercellular Communication | Patients with cystic fibrosis (CF) have airway inflammation that contributes to symptoms and to pulmonary function derangement. | 29246256 |
| ARCN1 gene, Inflammation, Pulmonary Emphysema | Altered Intercellular Communication | Platelet activation reduces pulmonary microvascular blood flow and contributes to inflammation; these factors have been implicated in the pathogenesis of COPD and emphysema. | 29246770 |
| Inflammation, Necrosis | Altered Intercellular Communication | The pathologic findings showed that although ischemic change (P = 0.43) and necrosis (P = 0.79) were observed in both groups, perivascular inflammation was observed only in the NBCA group (P = 0.006). | 29246879 |
| Airway structure | Altered Intercellular Communication | Staphylococcus aureus controls interleukin-5 release in upper airway inflammation. | 29247803 |
| Inflammation, Infection | Altered Intercellular Communication | Most of these infections are associated with milder inflammation compared to normal. | 29248323 |
| Inflammation, Neoplasms, Necrosis | Altered Intercellular Communication | In ten patients (0.5%), GBC was identified, each with an associated macroscopic finding, including local hardness (n = 1), a thickened wall (n = 5), acute inflammation and necrosis (n = 1), or suspected neoplasia (n = 3). | 29248400 |
| Inflammation, Pain Distress Question | Altered Intercellular Communication | Fibroblasts Promote Inflammation and Pain via IL-1a Induction of the Monocyte Chemoattractant Chemokine (C-C Motif) Ligand 2. | 29248462 |
| Inflammation | Altered Intercellular Communication | Using a combination of tissue protein expression profiling and bioinformatics, we discovered that many months after TKA, the fibrotic joint exists in a state of unresolved chronic inflammation. | 29248462 |
| Inflammation, Pain Distress Question | Altered Intercellular Communication | We propose that an IL-1a-NF-kB-CCL2 signaling pathway, operating within scar-associated fibroblasts, may be therapeutically manipulated for alleviating inflammation and pain in fibrotic joints and other tissues. | 29248462 |
| Inflammation, "Alzheimers Disease", Lewy Bodies, Dementia | Altered Intercellular Communication | Peripheral inflammation in prodromal Alzheimer's and Lewy body dementias. | 29248892 |
| Neurodegenerative Disorders, Inflammation, Lewy Bodies, Presenile dementia, "Alzheimers Disease", dendritic lamellar body, Data types - Address | Altered Intercellular Communication | There is growing evidence for the role of systemic inflammation in Alzheimer's disease (AD) and other neurodegenerative diseases; however the systemic inflammatory profile in dementia with Lewy bodies (DLB) has never before been investigated. | 29248892 |
| Inflammation, dendritic lamellar body, Data types - Address | Altered Intercellular Communication | We have shown for the first time that in both DLB and AD, increased peripheral inflammation occurs early at the MCI disease stages. | 29248892 |
| Inflammation | Altered Intercellular Communication | These data support a role for inflammation early in the disease process, and have important implications for the stage of disease where trials of anti-inflammatory medication should be focused. | 29248892 |
| Inflammation, Avascular necrosis of bone | Altered Intercellular Communication | Cytotoxic drugs may produce perivascular inflammation and ischemic necrosis. | 29252181 |
| Inflammation, Catatonia, Congenital Abnormality | Altered Intercellular Communication | Here, we showed that the underlying cause of catatonic signs is the low-grade inflammation of white matter tracts, which marks a final common pathway in Cnp-deficient and other mutant mice with minor myelin abnormalities. | 29252214 |
| Inflammation | Altered Intercellular Communication | Thus, microglia and low-grade inflammation of myelinated tracts emerged as the trigger of a previously unexplained mental condition. | 29252214 |
| Inflammation, diabetic | Altered Intercellular Communication | Diabetic status is characterized by chronic low-grade inflammation and an increased burden of senescent cells. | 29253812 |
| Hyperglycemia, Inflammation, Diabetes Mellitus | Altered Intercellular Communication | Overall, the present findings document a direct link between hyperglycaemia and the SASP in endothelial cells and macrophages, making the SASP a highly likely contributor to the fuelling of low-grade inflammation in diabetes. | 29253812 |
| Communicable Diseases, Anxiety, CTCAE 3.0, Depression, CTCAE | Altered Intercellular Communication | Shift in the methylation pathway, elevated cortisol, lowered neurotransmitter levels and lowered immune system allow infection to penetrate the body and lead to anxiety and depression. | 29254311 |
| Inflammation, Focal active colitis, Cryptitis, Fractional Area Change | Altered Intercellular Communication | The term focal active colitis (FAC) is conventionally used to describe the presence of isolated cryptitis, characterized by an inflammatory infiltrate consisting of intraepithelial neutrophils and/or neutrophils invading the lumen of the criptae, with no other microscopic alteration of the colonic mucosa and, in particular, without the presence of signs of chronic inflammation. | 29254324 |
| Inflammation | Altered Intercellular Communication | These results highlight the notion that memory decline and inflammation may be intertwined, and we discuss various avenues that warrant further investigation. | 29254429 |
| Inflammation, Fibrosis Assessment, Hyperpigmentation | Altered Intercellular Communication | Breast fibrosis (31.8%), puncture site inflammation (13.6%) and skin hyperpigmentation (11.4%) were the most frequent side effects. | 29254856 |
| Inflammation, Intimal proliferation | Altered Intercellular Communication | Transmural inflammation induces microvascular neoangiogenesis and results in lumen-occlusive intimal hyperplasia. | 29254929 |
| vascular inflammations, Giant Cell Arteritis | Altered Intercellular Communication | Vascular inflammation was induced in human arteries engrafted into immunodeficient mice that were reconstituted with T cells and monocytes from patients with giant cell arteritis. | 29254929 |
| Inflammation | Altered Intercellular Communication | Cytokine signaling dependent on JAK3 and JAK1 is critically important in chronic inflammation of medium and large arteries. | 29254929 |
| Myositis | Altered Intercellular Communication | It diminishes muscle tissue inflammation by decreasing the expression of costimulatory molecules MHC, CD86 and CD40 and reducing Th1-related cytokines IFN-g, IL-1b and TNF-a release. | 29255177 |
| ARCN1 gene, Inflammation, Cancer-related fatigue, Chronic Kidney Diseases | Altered Intercellular Communication | Considering that COPD patients usually have an ongoing prothrombotic state and systemic inflammation status, we investigated the association among them and explored the predictive value of a disintegrin and metalloproteinase with a thrombospondin type 1 motif, member 13 (ADAMTS-13), on concealed chronic renal failure (CRF) in COPD patients. | 29255356 |
| Cancer-related fatigue, Inflammation, ARCN1 gene | Altered Intercellular Communication | Prothrombotic state and systemic inflammation status might contribute to explaining the high incidence of concealed CRF in COPD, and plasma ADAMTS-13 levels may serve as a strong predictor. | 29255356 |
| Communicable Diseases, Inflammation | Altered Intercellular Communication | Immunosenescence is associated with increased susceptibility to infection and chronic low grade inflammation. | 29255925 |
| Tumor necrosis, Inflammation, Obesity | Altered Intercellular Communication | Tumor necrosis factor-a (TNF-a), peroxisome proliferator-activated receptor-g (PPARg), and insulin receptor substrate-1 (IRS-1) are associated with obesity, insulin resistance, and inflammation. | 29256014 |
| Inflammation, Fever, Hepatomegaly, Neck swelling | Altered Intercellular Communication | On examination he was febrile, had neck swelling with signs of inflammation and tender hepatomegaly. | 29256546 |
| Refractory anemias, Inflammation | Altered Intercellular Communication | In addition, the expression levels of PD-1 on T cells in the PB and SF of patients with RA were further analyzed to determine correlation with markers of the autoimmune response, inflammation and disease activity in RA. | 29257239 |
| Inflammation, Atrophy of pancreas, Atrophic | Altered Intercellular Communication | In addition, patients with EUS-CP findings had higher grades of pancreatic atrophy and inflammation than patients without EUS-CP findings (atrophy: 72.5% [29/40] vs. 34.5% [10/29], p = 0.003; inflammation: 45.0% [18/40] vs. 20.7% [6/29], p = 0.04). | 29258092 |
| Degenerative polyarthritis, Inflammation | Altered Intercellular Communication | We conclude that systemic levels of pro-inflammatory and angiogenic proteins are increased in patients with OA and rise further postoperatively, while proteins that restrain inflammation and angiogenesis do not coordinately rise. | 29258393 |
| Inflammation, Vitreous opacities | Altered Intercellular Communication | After 3 days of the above treatment, the anterior chamber inflammation and vitreous opacity were increased. | 29258454 |
| Inflammation, Diabetes Mellitus, Non-Insulin-Dependent, ETV3 wt Allele, Atherosclerosis | Altered Intercellular Communication | Yet, the clinical criteria for MetS are insensitive to the early-stage insulin resistance, inflammation, cholesterol and clotting factor abnormalities that characterize the progression toward type 2 diabetes and atherosclerosis. | 29258604 |
| Inflammation, Observation Method - Coagulation | Altered Intercellular Communication | Plasma and serum water T2 exhibited strong bivariate correlations with markers of insulin, lipids, inflammation, coagulation and electrolyte balance. | 29258604 |
| Increased insulin level, Dyslipidemias, Inflammation | Altered Intercellular Communication | After correcting for confounders, low water T2 values were independently and additively associated with fasting hyperinsulinemia, dyslipidemia and subclinical inflammation. | 29258604 |
| Heart failure | Altered Intercellular Communication | Inflammation-associated microRNA changes in circulating exosomes of heart failure patients. | 29258606 |
| Inflammation | Altered Intercellular Communication | As an acute presentation of inflammation, hemographic indices might be useful to identify subjects at risk of mortality soon after the index hospitalization. | 29259209 |
| Inflammation, Data types - Address | Altered Intercellular Communication | Oxidative stress and inflammation are considered to play an important role in the development and progression of AD. | 29259249 |
| Communicable Diseases, Inflammation | Altered Intercellular Communication | No evidence of infection, severe inflammation, leakage or hypotony was detected throughout the observation period. | 29260497 |
| Inflammation, Malignant Neoplasms | Altered Intercellular Communication | Increasing attention is focused on the relationship of inflammation biomarkers with malignant tumors. | 29262773 |
| Inflammation, Chronic disease | Altered Intercellular Communication | Systemic inflammation has been implicated in several chronic diseases. | 29262791 |
| Cerebral Small Vessel Diseases, Impaired cognition | Altered Intercellular Communication | Malnutrition-inflammation is a risk factor for cerebral small vessel diseases and cognitive decline in peritoneal dialysis patients: a cross-sectional observational study. | 29262796 |
| Inflammation, Coronary Artery Disease | Altered Intercellular Communication | Lipoprotein-associated phospholipase A2 (Lp-PLA2), a biomarker of oxidation and inflammation, has been associated with increased coronary artery disease risk. | 29262859 |
| Inflammation, Disease remission | Altered Intercellular Communication | Patients who are most likely to benefit from the PET/CT study would be those with several positive inflammation markers, reflecting a higher pre-test probability of active disease. | 29264739 |
| HD Term Type, Inflammation | Altered Intercellular Communication | Advanced age, time on dialysis, and inflammation may be associated with presence and extent of AAC in HD patients. | 29265045 |
| Inflammation, Fibrosis Assessment, Chronic liver disease | Altered Intercellular Communication | Activated hepatic macrophages play a key role in inflammation and fibrosis progression in chronic liver disease. | 29266346 |
| Inflammation, Recurrent lower respiratory tract infection, Cystic Fibrosis | Altered Intercellular Communication | Chronic lung infections, inflammation and depletion of nutritional status are considered to be prognostic indicators of morbidity in patients with cystic fibrosis. | 29267535 |
| Inflammatory abnormality of the eye | Altered Intercellular Communication | The patient underwent clinical treatments to control ocular inflammation. | 29267580 |
| Inflammation, MS gene | Altered Intercellular Communication | Importantly, functional STING was necessary for GCV to inhibit inflammation in cultured myeloid cells and in a mouse model of multiple sclerosis. | 29268096 |
| Inflammation, Joints | Altered Intercellular Communication | Synovial inflammation is very common in OA joints and has been associated with both OA's symptoms and pathogenesis. | 29268768 |
| Inflammation, Appendicitis, CTCAE | Altered Intercellular Communication | Appendicitis is defined as the bacterial proliferation and inflammation of the vermiform appendix, typically caused by a fecalith . | 29269161 |
| Pancreatitis, Pancreatic carcinoma, Atrophic, Intraductal papillary mucinous neoplasm | Altered Intercellular Communication | Pancreatic inflammation and atrophy are not associated with pancreatic cancer concomitant with intraductal papillary mucinous neoplasm. | 29269290 |
| Carcinogenesis, Intraductal papillary mucinous neoplasm, ANOPHTHALMIA AND PULMONARY HYPOPLASIA, Pancreatic Intraductal Papillary Mucinous Neoplasm, Pancreatic Ductal Adenocarcinoma | Altered Intercellular Communication | Inflammation-induced carcinogenesis in pancreatic ductal adenocarcinoma (PDAC) has been reported; however, its involvement in PDAC with intraductal papillary mucinous neoplasm (IPMN) remains unclear. | 29269290 |
| Inflammation, Pancreatic Intraductal Papillary Mucinous Neoplasm, Atrophy of pancreas | Altered Intercellular Communication | We herein investigated the relationship between pancreatic atrophy and inflammation and the incidence of PDAC concomitant with IPMN. | 29269290 |
| Pancreatitis, Atrophic | Altered Intercellular Communication | Pathological pancreatic inflammation and atrophy were evaluated in resected specimens. | 29269290 |
| Pancreatitis, Pancreatic Intraductal Papillary Mucinous Neoplasm, Atrophic | Altered Intercellular Communication | High degrees of pancreatic inflammation and atrophy were not associated with the incidence of PDAC with IPMN (multivariable odds ratio [OR] = 0.5, 95% confidence interval [CI] = 0.07 to 3.33, P = .52, adjusted by clinical characteristics, OR = 0.9, 95% CI = 0.10 to 5.86, P = .91, adjusted by imaging studies; OR = 0.2, 95% CI = 0.009 to 1.31, P = .10, adjusted by clinical characteristics, OR = 0.2, 95% CI = 0.01 to 1.43, P = .12, adjusted by imaging studies, respectively). | 29269290 |
| Pancreatitis, Pancreatic Intraductal Papillary Mucinous Neoplasm, Atrophic, Pancreatic carcinoma | Altered Intercellular Communication | Pancreatic inflammation and atrophy were not associated with pancreatic cancer concomitant with IPMN. | 29269290 |
| Distress, Inflammation | Altered Intercellular Communication | Chronic distress associates with peripheral release of cortisol and a parallel upregulation of innate inflammation. | 29269321 |
| Inflammation, Refractory anemias, Communicable Diseases, Electrocardiogram: myocardial infarction (finding), Coronary heart disease, Rheumatoid Arthritis, Choline Dehydrogenase, Mitochondrial | Altered Intercellular Communication | Rheumatoid arthritis (RA) disease activity and associated systemic inflammation has been associated with serious infection (SIEs), myocardial infarction (MI) and coronary heart disease (CHD) events based on a few registry studies or clinical trials. | 29269418 |
| Infarction, Inflammation, Fibrosis Assessment | Altered Intercellular Communication | In conclusion, LAIR-1 expression on monocytes and neutrophils is increased in the acute phase after MI in patients, but the absence of LAIR-1 in mice does not influence infarct size, inflammation, fibrosis or adverse cardiac remodelling. | 29269840 |
| Bronchiectasis | Altered Intercellular Communication | Is There a Correlation between New Scoring Systems and Systemic Inflammation in Stable Bronchiectasis? | 29270068 |
| Inflammation, Bronchiectasis | Altered Intercellular Communication | In patients with stable bronchiectasis who are evaluated based on FACED and BSI scores, CRP can be a useful biomarker as a direct indicator of the severity of systemic inflammation. | 29270068 |
| Inflammation, Atrial Fibrillation by ECG Finding | Altered Intercellular Communication | The risk of atrial fibrillation may depend on the interaction between n-3 and n-6 polyunsaturated fatty acids as both types of fatty acids are involved in the regulation of systemic inflammation. | 29272310 |
| Inflammation, Psoriasis, Inflammatory disorder | Altered Intercellular Communication | Psoriasis is a chronic inflammatory cutaneous disorder with undefined etiology and is characterized by abnormal cellular proliferation, angiogenesis, and inflammation. | 29272319 |
| Crohn Disease | Altered Intercellular Communication | Validation of Neutrophil CD64 Blood Biomarkers to Detect Mucosal Inflammation in Pediatric Crohn's Disease. | 29272485 |
| Crohn Disease, Gastrointestinal inflammation | Altered Intercellular Communication | In a large Crohn's disease cohort, we found that neutrophil CD64 index and soluble CD64 were significantly elevated during active gastrointestinal inflammation. | 29272485 |
| Thrombotic Microangiopathies, Inflammation, Pulmonary Hypertension | Altered Intercellular Communication | In pulmonary tumor thrombotic microangiopathy, local inflammation in pulmonary microvasculature may contribute to pulmonary hypertension, and regulation of inflammation using corticosteroids may help improve the prognosis. | 29273073 |
| Osteoporosis | Altered Intercellular Communication | Our findings highlight pleiotropic modulations of metabolism- and inflammation-related genes in the development of osteoporosis and demonstrate the contribution of pleiotropic genetic variants in prediction of osteoporosis risk. | 29273888 |
| Hematoxylin and eosin stain method, Inflammation | Altered Intercellular Communication | We assessed the degree of inflammation of the bladder wall on slides stained with hematoxylin and eosin (H&E). | 29277923 |
| Hematoxylin and eosin stain method, Inflammation | Altered Intercellular Communication | With H&E staining, we detected 13, 15, and 12 patients with mild, moderate, and severe inflammation. | 29277923 |
| Inflammation, Bladder pain | Altered Intercellular Communication | The degree of inflammation was negatively correlated with disease course (P = 0.018) and positively correlated with bladder pain (P < 0.001). | 29277923 |
| Cystitis | Altered Intercellular Communication | PD-L1 expression is more common in IC patients with severe bladder inflammation. | 29277923 |
| Tubulitis Assessment, Interstitial inflammation | Altered Intercellular Communication | Morphological changes in the transplanted kidneys, such as tubulitis (p = 0.025) and interstitial inflammation (p = 0.002), were significantly more frequently present in patients with ECD kidneys than in those with IDK 1 year after transplantation. | 29278028 |
| Chronic sinusitis, Depression, CTCAE | Altered Intercellular Communication | The sinonasal microbiota, neural signaling, and depression in chronic rhinosinusitis. | 29278464 |
| Depression, CTCAE | Altered Intercellular Communication | Several commonly "health-associated" sinonasal bacterial taxa were positively associated with higher neurotransmitter concentrations and negatively associated with depression severity. | 29278464 |
| Inflammation, Neoplasms | Altered Intercellular Communication | If destruction of these cells occurs due to inflammation or tumour, CA 125 will be released, and increased in the serum. | 29278633 |
| Airway structure, Asthma | Altered Intercellular Communication | Exhaled nitric oxide is believed be a useful surrogate for airways inflammation while non-adherence with therapy is known to be associated with worsening of asthma control. | 29278953 |
| Inflammation, Granuloma | Altered Intercellular Communication | The microscopic findings in biopsies included active chronic inflammation with prominent eosinophils and granulomas. | 29278974 |
| Inflammation, Fibrosis Assessment, Liver Stiffness | Altered Intercellular Communication | Liver stiffness measured by MRE was correlated with the grade of fibrosis and/or inflammation determined by liver biopsy. | 29279175 |
| Inflammation, Fibrosis Assessment, Fatty degeneration, Non-alcoholic Fatty Liver Disease, Liver Stiffness | Altered Intercellular Communication | NAFLD patients with inflammation and without fibrosis have higher liver stiffness than those with simple steatosis. | 29279175 |
| Inflammation | Altered Intercellular Communication | The inflammation score was significantly lower in 2nd DESs compared to 1st DESs (1.02+-0.16 vs. 1.19+-0.54, p<0.05). | 29279291 |
| Coughing, Inflammation, Vagus nerve branch | Altered Intercellular Communication | While inflammation of either the ascending pharyngeal or pulmonary artery have been reported to cause cough in patients with LVV, the present case shows that intense inflammation of the aortic arch and the starting portion of its main branches may stimulate a vagus nerve branch as a novel mechanism causing cough. | 29279466 |
| Coughing, Vasculitis of large artery, Takayasu Arteritis | Altered Intercellular Communication | We suspected that the cough reflex pathway had been stimulated by large vessel vasculitis (LVV, a non-respiratory inflammatory condition) and diagnosed the patient with Takayasu arteritis. | 29279466 |
| Inflammation, Fibrosis Assessment | Altered Intercellular Communication | The examination of a liver biopsy specimen revealed fatty droplets, ballooning, inflammation, and mild fibrosis. | 29279489 |
| Neurodegenerative Disorders, Inflammation | Altered Intercellular Communication | Microglia and macrophages are the main non-neuronal subsets of myeloid origin in the brain, and are critical regulators in neurodegenerative disorders, where inflammation is a key factor. | 29280055 |
| Inflammation, Age related macular degeneration, Necrosis | Altered Intercellular Communication | ARMD is characterized by local severe inflammation and tissue necrosis leading to implant failures. | 29280283 |
| Intraocular inflammation, Pain, Postoperative | Altered Intercellular Communication | Intraocular inflammation, intraocular pressure (IOP), and the intensity of postoperative pain were compared between the groups. | 29283786 |
| Inflammation | Altered Intercellular Communication | Carotid Atheroma From Men Has Significantly Higher Levels of Inflammation and Iron Metabolism Enabled by Macrophages. | 29284736 |
| Inflammation, Acute Coronary Syndrome, Myocardial Infarction | Altered Intercellular Communication | Neutrophil-to-lymphocyte Ratio and Its Relation with Markers of Inflammation and Myocardial Necrosis in Patients with Acute Coronary Syndrome. | 29284896 |
| Inflammation, Angina, Unstable, Atherosclerosis, Acute Coronary Syndrome, Acute myocardial infarction, GDC AJCC Clinical Stage Terminology | Altered Intercellular Communication | Inflammation plays an important role in atherosclerosis which is the primary cause of acute coronary syndrome (ACS) that encompasses acute myocardial infarction (AMI) and unstable angina (UA). | 29284896 |
| Inflammation, Myocardial Infarction, Myocardial lesion, GDC AJCC Clinical Stage Terminology | Altered Intercellular Communication | A positive correlation was established between NLR and markers of myocardial necrosis, and between NLR and CRP, indicating the importance of NLR in the assessment of the extent of the myocardial lesion and in inflammation intensity assessment in ACS. | 29284896 |
| Inflammation | Altered Intercellular Communication | Therefore, other pathophysiological processes such as inflammation might also substantially affect sST2 plasma levels. | 29285671 |
| Fibrosis Assessment, Myocarditis | Altered Intercellular Communication | Galectin-3 belongs to a class of inflammatory mediators that is associated with the degree of myocardial inflammation and fibrosis. | 29287900 |
| Inflammation, Pancreatitis | Altered Intercellular Communication | GIP and peptide YY appear to be involved in perpetuation of subclinical inflammation following an episode of acute pancreatitis, which is known to play an important role in the pathogenesis of blood glucose derangements. | 29288273 |
| Arterial Stiffness, vascular inflammations, Cardiovascular Diseases, Atherosclerosis | Altered Intercellular Communication | In T2DM patients without established cardiovascular disease, novel indices of vascular inflammation (NGAL and YKL-40) were associated with subclinical atherosclerosis (arterial stiffness) but also with adverse clinical prognosis. | 29288632 |
| Inflammation, Calcinosis, Calcification of basal ganglia | Altered Intercellular Communication | Considering the role of fetuin-A in tissue calcification and inflammation, higher serum fetuin-A levels should be measured in patients with basal ganglia calcification. | 29288724 |
| Inflammation, Vasoplegia, Endothelial dysfunction | Altered Intercellular Communication | Increased systemic inflammation and endothelial dysfunction, often related to prolonged cardiopulmonary bypass times, anesthesia, or mechanical circulatory support have been shown to be associated with the development of vasoplegia. | 29289367 |
| Inflammation, Ulcerative Colitis | Altered Intercellular Communication | For FC, a cut-off value of 250 mg/g indicated endoscopic active inflammation with accuracies of 87.5%, 60%, and 91.1%, respectively, for CICD, CD-related surgery, and UC patients. | 29290660 |
| Ulcerative Colitis, Inflammatory disease of mucous membrane | Altered Intercellular Communication | Also, the diagnostic accuracy of FC in identifying patients with mucosal inflammation in clinical remission was reflected by an AUC of 0.91 for CICD and 0.96 for UC patients. | 29290660 |
| Inflammation, Cardiovascular Diseases | Altered Intercellular Communication | This may indicate that the effects of early stressors on later inflammation operate through pathways with clear links to cardiovascular disease. | 29291495 |
| Inflammation, Diabetes Mellitus | Altered Intercellular Communication | Ingenuity pathway analysis showed routes with differentially methylated CpG sites (CpGs) related to intermediate metabolism, diabetes, inflammation, and signal transduction. | 29295516 |
| Inflammation, Diabetes Mellitus | Altered Intercellular Communication | These changes may have potential benefits in health; especially those changes in genes related to intermediate metabolism, diabetes, inflammation and signal transduction, which may contribute to explain the role of MedDiet and fat quality on health outcomes. | 29295516 |
| Diabetic Retinopathy, Inflammatory abnormality of the eye, PDR gene | Altered Intercellular Communication | To evaluate whether NETosis is involved in cytokine-induced ocular inflammation and to track neutrophil extracellular traps (NET) complexes in patients with proliferative diabetic retinopathy (PDR). | 29296072 |
| Intraocular inflammation | Altered Intercellular Communication | Her left eye vision and intraocular inflammation improved after commencement of chemotherapy. | 29308780 |
| Inflammation | Altered Intercellular Communication | A bone biopsy specimen of the mandibular lower border did not have inflammation or cytologic atypia. | 29310888 |
| Inflammation | Altered Intercellular Communication | The role of inflammation is poorly understood in AIR. | 29310941 |
| Inflammation | Altered Intercellular Communication | Since cytokines play a central role in the initiation and development of inflammation, we evaluated the presence of proinflammatory cytokines and chemokines in AIR patient sera. | 29310941 |
| Inflammation | Altered Intercellular Communication | Markers of inflammation/infection and blood cultures were obtained before and 24 h after EVL. | 29317174 |
| Delirium, Inflammation | Altered Intercellular Communication | Markers of inflammation as risk predictors of lethal outcome in patients diagnosed with delirium. | 29320220 |
| Inflammation, Fibrosis Assessment | Altered Intercellular Communication | Thyroid gland histology demonstrated perifollicular or interlobular fibrosis without inflammation in all three cases, including a euthyroid case. | 29325681 |
| Inflammation | Altered Intercellular Communication | The oral microbiota plays a critical role in both local and systemic inflammation. | 29326886 |
| Inflammation, Metabolic Syndrome X, ETV3 wt Allele | Altered Intercellular Communication | Metabolic syndrome (MetS) is characterized by low-grade inflammation, and many studies have been conducted on the gut microbiota from stool specimens. | 29326886 |
| Pulpitis | Altered Intercellular Communication | Several cytokines and lymphokines (IL1b, ENA78, IL6, TNFa, IL8 and S100A8) are expressed during dental pulp inflammation. | 29328596 |
| Gingivitis, Inflammation, Tooth structure | Altered Intercellular Communication | Although GCF levels of various mediators could reflect the state of inflammation both in dental pulp and gingiva adjacent to a tooth, GCF samples of those without significant gingivitis could be inter-preted as reflection of pulpal process. | 29328596 |
| Inflammation, Fracture | Altered Intercellular Communication | The procedure alone and related mechanical factors seem to be associated with acute/subacute ST. On the other hand, in-stent neoathero-sclerosis, inflammation, premature cessation of antiplatelet therapy, as well as stent fracture, stent malapposition, un-covered stent struts may play role in late/very late ST. | 29328614 |
| Inflammation, Diabetes Mellitus | Altered Intercellular Communication | In this multiethnic population, the 12% higher diabetes risk for long sleep hours may be mediated through inflammation, a poor lipid profile, and lower adiponectin levels. | 29332675 |
| Inflammation | Altered Intercellular Communication | Hyperreactivity of the airways caused by inflammation in asthmatics is the most important pathophysiological change. | 29338164 |
| Acute and chronic inflammation | Altered Intercellular Communication | These include reduction of chronic inflammation markers, improvement of walking mechanics and heart function. | 29339594 |
| Stanford Cancer Institute, Communicable Diseases, Inflammation, Fever, CTCAE | Altered Intercellular Communication | Does the CDC Definition of Fever Accurately Predict Inflammation and Infection in Persons With SCI? | 29339867 |
| Communicable Diseases, Inflammation, Fever, CTCAE | Altered Intercellular Communication | Fever is often the first presenting symptom of infection or inflammation. | 29339867 |
| Inflammation, Communicable Diseases, Fever, Memory dysfunction, Stanford Cancer Institute | Altered Intercellular Communication | Thermoregulatory dysfunction in persons with SCI may preclude a typical febrile response to infection or inflammation and thus delay diagnostic workup. | 29339867 |
| Inflammation, Centers for Disease Control and Prevention (U.S.), Fever, CTCAE, Communicable Diseases, Stanford Cancer Institute | Altered Intercellular Communication | Objective: To determine the core temperature of persons with SCI in the setting of infection or inflammation and the frequency with which it meets criteria for the CDC definition of fever (>100.4degF). | 29339867 |
| Inflammation, Leukocytosis, Diego blood group system, Communicable Diseases, Stanford Cancer Institute | Altered Intercellular Communication | Methods: Retrospective review of hospitalized SCI patients over 5 years with a diagnosis of infection or inflammation (DI), defined by serum leukocytosis. | 29339867 |
| Communicable Diseases, Inflammation, Stanford Cancer Institute | Altered Intercellular Communication | Tau >100.4degF is not a sensitive predictor of infection or inflammation in persons with SCI. | 29339867 |
| Communicable Diseases, Inflammation | Altered Intercellular Communication | Clinicians should be vigilant for alternative symptoms of infection and inflammation in these patients, so diagnostic workup is not delayed. | 29339867 |
| Spinal Cord Injuries | Altered Intercellular Communication | The Influence of Chronic Inflammation on Peripheral Motor Nerve Conduction Following Spinal Cord Injury: A Randomized Clinical Trial. | 29339913 |
| Inflammation, Spinal Cord Injuries, Stanford Cancer Institute, Peripheral Nerves | Altered Intercellular Communication | Objective: To examine the potential influence of chronic inflammation on peripheral motor nerve function in vivo following spinal cord injury (SCI). | 29339913 |
| Inflammation, Chronic Kidney Diseases | Altered Intercellular Communication | Chronic kidney disease (CKD) is accompanied by inflammation. | 29349065 |
| Pneumonitis | Altered Intercellular Communication | It is characterized by chronic pulmonary inflammation and obstructed airflow from the lungs. | 29351440 |
| Inflammation, Fibrosis Assessment | Altered Intercellular Communication | Because agrin can induce only mild cardiomyocyte proliferation compared with ERBB2 pathway activation, it might exert pleiotropic effects, such as mitigation of innate inflammation, immune response, and fibrosis. | 29351440 |
| Communicable Diseases, Inflammation | Altered Intercellular Communication | PS or FS was considered to be positive for infection when at least one of the specimens demonstrated an acute inflammation. | 29352690 |
| Inflammation | Altered Intercellular Communication | PS had a better diagnostic utility than FS suggesting that areas of acute inflammation may be scattered and may not always be captured in the specimens taken for FS. | 29352690 |
| Inflammation, Giant Cell Arteritis, Aortitis | Altered Intercellular Communication | Imaging giant cell arteritis and Aortitis in contrast enhanced 18F-FDG PET/CT: Which imaging score correlates best with laboratory inflammation markers? | 29362158 |
| Inflammation | Altered Intercellular Communication | Adults and Biomarkers of Inflammation, Oxidative Stress, and Endothelial Dysfunction: A Cross-Sectional Study. | 29373859 |
| Inflammation, Chronic Kidney Diseases | Altered Intercellular Communication | Chronic kidney disease (CKD) is known as a state of chronic low-grade inflammation, enhancing cardiovascular risk and immunodeficiency. | 29375053 |
| Inflammation, Chronic Kidney Diseases | Altered Intercellular Communication | In conclusion, the increased P2X7 receptors expression in monocytes, the monocyte count and the Ne/Ly ratio are manifestations of chronic inflammation already in early stages of CKD. | 29375053 |
| Hyperlipidemia, Inflammation, Atherosclerosis | Altered Intercellular Communication | Hyperlipidemia and inflammation play important roles in the development and progression of atherosclerosis. | 29389579 |
| Inflammation, Corneal Ulcer | Altered Intercellular Communication | A reduction in the inflammation and healing of the corneal ulcer could be seen. | 29390295 |
| Pancreatic Ductal Adenocarcinoma | Altered Intercellular Communication | Prognostic value of postdiagnostic inflammation-based scores in short-term overall survival of advanced pancreatic ductal adenocarcinoma patients. | 29390358 |
| Pancreatic carcinoma | Altered Intercellular Communication | The prognostic relevance of commonly used composite inflammation-based scores remains severely underdiscussed in pancreatic cancer (PC), especially for advanced PC. | 29390358 |
| Arthritis, Chondritis of pinna, Fever, CTCAE, Inflammatory abnormality of the eye | Altered Intercellular Communication | A 26-year-old woman complained about recurrent fever, auricular chondritis, ocular inflammation, and arthritis. | 29390537 |
| Communicable Diseases, Arthritis, Inflammation | Altered Intercellular Communication | As both ESR and CRP are markers of systemic inflammation, the utility of these tests to monitor infection clearance in patients with inflammatory arthritis is unclear. | 29395719 |
| Cessation of life, Inflammation, Primary malignant neoplasm, Neoplasms | Altered Intercellular Communication | Cell Death, Inflammation, Tumor Burden, and Proliferation Blood Biomarkers Predict Lung Cancer Radiotherapy Response and Correlate With Tumor Volume and Proliferation Imaging. | 29398577 |
| Inflammation, Hypoxia, caspase | Altered Intercellular Communication | Twenty-six cell-death, hypoxia, angiogenesis, inflammation, proliferation, invasion, and tumor-burden biomarkers were evaluated. | 29398577 |
| Aneurysm, Retinal Vasculitis, Juxtapapillary focal retinitis AND retinochoroiditis, Inflammation | Altered Intercellular Communication | Idiopathic retinal vasculitis, aneurysms and neuroretinitis (IRVAN) syndrome is a rare entity of unknown etiology for which many hypotheses have been proposed with inflammation being the most commonly accepted hypothesis. | 29406987 |
| Vascular anomaly, Inflammation | Altered Intercellular Communication | Our conclusions and interpretation point towards IRVAN being a developmental vascular anomaly rather than a consequence of inflammation. | 29406987 |
| Inflammation, Spondylarthritis | Altered Intercellular Communication | In our study, foot involvement and foot symptoms were seen frequently in spondyloarthritis and it is associated with late onset of the disease and with higher inflammation in blood tests. | 29409278 |
| Inflammation, Metabolic Syndrome X | Altered Intercellular Communication | Metabolic syndrome (MetSyn) is characterized by chronic inflammation which mediates the associated high risk for cardiovascular and other diseases. | 29413356 |
| Inflammation | Altered Intercellular Communication | While their role as locally produced agents is appreciated, most oxylipins in plasma are found in lipoproteins suggesting defective regulation of inflammation could be mediated by the elevated VLDL and low HDL levels characteristic of MetSyn. | 29413356 |
| Inflammation, Malnutrition, Cachexia, Sarcopenia | Altered Intercellular Communication | The prevalence of sarcopenia was significantly higher in patients with malnutrition (71.2% vs 12.3%; p < 0.001), especially in those with systemic inflammation (cachectic patients) (85.7% vs 61.3%; p < 0.001). | 29413494 |
| Inflammation, Sarcopenia | Altered Intercellular Communication | In addition, clear-cut changes in raw BIA variables were observed in malnourished patients with systemic inflammation and sarcopenic patients. | 29413494 |
| Uremia, Inflammation | Altered Intercellular Communication | Inflammation is considered as a major player in uremia associated with morbidity and mortality in hemodialysis patients. | 29415829 |
| Intraocular inflammation, Postoperative Complications, Glaucoma, CTCAE | Altered Intercellular Communication | The primary outcome was mean intraocular pressure (IOP) at 6 months; secondary outcomes were change in glaucoma medications, visual acuity, intraocular inflammation, and postoperative complications. | 29422751 |
| Inflammation, Malnutrition | Altered Intercellular Communication | About half of the patients had inflammation cumulated with malnutrition. | 29442459 |
| Inflammation, Congenital laryngeal abductor palsy, Linear IgA Bullous Dermatosis | Altered Intercellular Communication | Linear IgA bullous dermatosis (LABD) is an autoimmune subepidermal blistering disease usually with a neutrophil rich inflammatory infiltrate, and characterized by linear IgA deposition at the basement membrane zone (BMZ), and neutrophil predominant dermal inflammation. | 29447641 |
| Inflammation, Atrial Fibrillation by ECG Finding | Altered Intercellular Communication | Multiple prospective studies have established an association between inflammation and higher risk of atrial fibrillation (AF), but the association between lipoprotein-associated phospholipase A2 (Lp-PLA2) mass and activity and incident AF has not been extensively evaluated. | 29447785 |
| Granulomatous inflammation | Altered Intercellular Communication | Histology showed a diffuse, granulomatous inflammation including numerous plasma cells. | 29449723 |
| Retinal Vein Occlusion, Inflammation, Hyperviscosity syndrome | Altered Intercellular Communication | When a patient less than 50 years of age experiences central retinal vein occlusion, other mechanisms, such as the hyperviscosity syndrome or the inflammatory condition (inflammation of the central retinal vein) should be specifically considered and accounted for. | 29450334 |
| Retinal Vein Occlusion, Inflammation, Hyperviscosity syndrome | Altered Intercellular Communication | When a patient less than 50 years of age experiences central retinal vein occlusion, other mechanisms, such as the hyperviscosity syndrome or the inflammatory condition (inflammation of the central retinal vein) should be specifically considered and accounted for. | 29450334 |
| Glaucoma, Open-Angle, Pyloric Stenosis | Altered Intercellular Communication | The unilateral pseudophakic open-angle pigmentary glaucoma occurred in the context of rubbing of the haptics and optic of a posterior chamber intraocular lens implanted in the sulcus, against the posterior surface of the iris, with resultant pigment dispersion, trabecular inflammation, and aqueous outflow obstruction. | 29450335 |
| Inflammation, Glaucoma, CTCAE, Traumatic injury, Neoplasms | Altered Intercellular Communication | Six disease categories were followed: inflammation, trauma, vascular, tumor, glaucoma, and retinal-vitreal. | 29450342 |
| Pain Distress Question, Inflammation, Corneal Ulcer | Altered Intercellular Communication | After 2 weeks, his symptoms diminished, pain was significantly relieved and inflammation was markedly reduced, but the corneal ulcer persisted. | 29450349 |
| Neurogenic Inflammation, Osseous metaplasia, Traumatic injury | Altered Intercellular Communication | Conclusions: In spite of a rare occurrence, our case emphasized the theory that trauma and subsequent neurogenic inflammation could lead to osseous metaplasia. | 29450374 |
| Retinal Neovascularization, Inflammation, Eales disease, Ischemia, Vitreous Hemorrhage, Unspecified visual loss | Altered Intercellular Communication | Eales disease is an idiopathic peripheral vascular occlusive disease characterized by inflammation, ischemia, and retinal neovascularization and is hallmarked by recurrent vitreous hemorrhages and vision loss. | 29450389 |
| Primary malignant neoplasm | Altered Intercellular Communication | Impact of Elevated Circulating Histones on Systemic Inflammation after Radiofrequency Ablation in Lung Cancer Patients. | 29457035 |
| Hypercholesterolemia, Hypertriglyceridemia, Liver Dysfunction, Inflammation | Altered Intercellular Communication | Hypercholesterolemia and hypertriglyceridemia as risk factors of liver dysfunction in children with inflammation receiving total parenteral nutrition. | 29460791 |
| Klinefelter Syndrome, Obstructive azoospermia | Altered Intercellular Communication | Clinical, Hormonal, and Genetic Evaluation of Idiopathic Nonobstructive Azoospermia and Klinefelter Syndrome Patients. | 29466784 |
| Inflammation, Diabetes Mellitus | Altered Intercellular Communication | Males may present to their primary care provider with a bothersome inflammation of the penis that may be the first recognition of previously undiagnosed diabetes. | 29467066 |
| Inflammation, Balanitis | Altered Intercellular Communication | Balanitis is an inflammation of the glans of the penis that may prompt a patient to seek medical care. | 29467066 |
| Infection | Altered Intercellular Communication | In some cases, different types of infections or inflammatory conditions may prompt a patient to seek medical attention. | 29467066 |
| Granulomatous inflammation | Altered Intercellular Communication | Lesional punch biopsies repeatedly showed non-specific granulomatous inflammation with no pathogens evident histologically or by culture. | 29469695 |
| Communicable Diseases, Inflammation, Pathology, Aortitis | Altered Intercellular Communication | The inflammation of aortic wall, named aortitis, is a rare condition that can be caused by a number of pathologies, mainly inflammatory or infectious in nature. | 29489984 |
| Inflammation, Myocardial Reperfusion | Altered Intercellular Communication | CABG surgery-induced myocardial reperfusion damage and subsequent inflammation were related to changes in miR-1, miR-133a, and miR-208a. | 29506853 |
| Inflammation, Heart Injuries | Altered Intercellular Communication | Notably, miR-208a was the only indicator associated with CK-MB, cTnT, and IL-6, which may reflect heart injury and inflammation in these patients. | 29506853 |
| Inflammation | Altered Intercellular Communication | Serum n-6 PUFAs were not associated with increased inflammation in men. | 29515239 |
| Eales disease, Retinal Diseases, Retinitis | Altered Intercellular Communication | Eales disease is a clinical diagnosis of exclusion as many other retinal disorders can mimic it, especially conditions of retinal inflammation or neovascularization. | 29516052 |
| Inflammation, Disorder of tendon | Altered Intercellular Communication | Is the inflammation process absolutely absent in tendinopathy of the long head of the biceps tendon? | 29517202 |
| Inflammation, Disorder of tendon | Altered Intercellular Communication | This study demonstrates the prevalence of the degeneration process and the presence of marginal inflammation process in tendinopathy of the long head of biceps tendon. | 29517202 |
| Inflammation, Disorder of tendon | Altered Intercellular Communication | The role, that inflammation process plays in tendinopathy is important in the early phase and gradually becomes secondary to the developing degeneration. | 29517202 |
| Airway structure | Altered Intercellular Communication | One of the most serious complications of IPA is airway inflammation which commonly leads to severe obstruction. | 29519693 |
| Weight Gain, Hyperphagia, Central hypoventilation | Altered Intercellular Communication | Patients between the ages of 2 and 4 present with hyperphagia and weight gain, followed by neuro-hormonal dysfunction and central hypoventilation months or years later. | 29543408 |
| Inflammatory disease of mucous membrane | Altered Intercellular Communication | Osteoneogenesis and chronic mucosal inflammation could be controlled by creating a large drainage pathway. | 29553611 |
| Inflammation, hearing impairment, Communicable Diseases, Chronic purulent otitis media, Granulation finding, Cholesteatoma | Altered Intercellular Communication | Chronic suppurative otitis media (CSOM) with and without cholesteatoma is regarded as chronic inflammation of the middle ear and mastoid mucosa that can be associated with the presence of granulation tissue and infection, which can lead to ossicular damage and hearing loss, but it is commonly known that cholesteatoma behaves aggressively. | 29556625 |
| Inflammation, Damage | Altered Intercellular Communication | Angiogenesis is an important part of inflammatory process, enhancing inflammation in a vicious circle that aggravates mucosal damage and remodeling. | 29556626 |
| Inflammation, Ulcerative Colitis | Altered Intercellular Communication | In our study, patients with UC have correlated increases of VEGF expression and microvessel density (evaluated with CD105 staining), sustaining the hypothesis that angiogenesis is not just a passive process driven by inflammation, but an active player of mucosal lesions in ulcerative colitis. | 29556626 |
| Inflammation, Visual Impairment | Altered Intercellular Communication | Follow-up over 6 months showed authentic absence of left eye vision impairment, no signs of recurrence of the median palatine cyst, and no acute inflammation in the nasal cavity or paranasal sinus area. | 29557566 |
| Inflammation, Chronic infectious disease | Altered Intercellular Communication | However, its structure, with chronic inflammation and detritus, can be regarded as a focus of chronic infection. | 29557566 |
| Inflammation, Pain Distress Question, Communicable Diseases, Swelling, Hypersensitivity | Altered Intercellular Communication | Inflammation associated with allergic reaction to any of these materials (metallic and/or acrylic bone cement) can plausibly cause a number of similar manifestations to infection such as loosening, instability, stiffness, arthrofibrosis, swelling, warmth, and pain. | 29604945 |
| Crohn Disease, Inflammation | Altered Intercellular Communication | Crohn's disease is a disorder characterized by transmural inflammation which can potentially affect any part of the gastrointestinal tract from the mouth to the perianal area. | 29611683 |
"
| Gastroesophageal reflux disease, Overweight, Esophagitis, Heartburn | Altered Intercellular Communication | This study demonstrates
that overweight predispose to
esophageal inflammation and increase
the frequency of heartburn and sleep
problems in GERD patients. | 29629738 | "
"
| Tears body substance, Inflammation, Visual disturbance, Ocular surface disease | Altered Intercellular Communication | Ocular surface disease (OSD) is a multifactorial disease of the tears and ocular surface that
results in symptoms of discomfort, visual disturbances, tear film instability with potential damage to the
ocular surface, accompanied by increased tear film osmolarity and inflammation of the ocular surface. | 29652117 | "
"
| Inflammation, Salivary Gland Tissue, Necrosis, Vascular Invasion Assessment, Calcinosis, Acantholysis, Muscle (organ) | Altered Intercellular Communication | Apoptotic
cells (n = 26), atypical mitosis (1-2/20x; n = 38), giant cells (n = 8), acantholysis (n = 5), necrosis (n = 5),
calcification (n = 1), granulation tissue (n = 32), desmoplasia (n = 4), perineural invasion (n = 2), muscular
invasion (n = 8), invasion of salivary gland tissue (n = 3), vascular invasion (n = 10), and chronic inflammation
(n = 33) were observed. | 29652445 | "
| Inflammation, Vascular calcification, Cardiovascular Diseases, AHSG protein, human, Cyclophosphamide/Vincristine/Dacarbazine Regimen | Altered Intercellular Communication | Fetuin-A is an inhibitor of vascular calcification, and pentraxin 3 (PTX3) is produced at the site of inflammation, which is associated with cardiovascular disease (CVD). | 29664315 |
| Inflammation, Diabetic Angiopathies | Altered Intercellular Communication | According to our results, these 2 parameters may potentially serve as suitable markers for inflammation and prediction of vascular complications in these patients. | 29664315 |
| Inflammation, Osteoarthritis, Knee | Altered Intercellular Communication | We hypothesized that supplementing with creatine monohydrate for 12 weeks would lower biomarkers of inflammation and cartilage degradation in patients with knee osteoarthritis when compared to placebo. | 29673544 |
| Inflammation, Perianal fistula | Altered Intercellular Communication | Perianal fistula is usually of cryptoglandular origin, namely it results from inflammation of the anal glands. | 29693853 |
| Endometriosis | Altered Intercellular Communication | Endometriosis is a pathological, benign, inflammatory condition characterized by the presence of endometrial glands and stroma outside the uterine cavity, typically in the pelvis. | 29701376 |
| IgG4-Related Sclerosing Disease | Altered Intercellular Communication | IgG4-related disease (IgG4-RD) is an immune- -mediated fibro-inflammatory condition with unknown etiology that can affect various organs. | 29701393 |
| Inflammation, Fibrosis Assessment, Blood Clot, Stenosis Morphology | Altered Intercellular Communication | Vessel inflammation leads to wall thickening, fibrosis, stenosis, and thrombus formation. | 29701396 |
| Pain Distress Question, Morbidity - disease rate | Altered Intercellular Communication | Thoracotomy incisions are associated with severe pain, leading to a decrease in pulmonary function, an increase in metabolic and hormonal activity and increased cardiac morbidity. | 29701425 |
| Inflammation, Rhinosinusitis | Altered Intercellular Communication | Rhinosinusitis is characterized by inflammation of the sinuses, resulting in particular symptoms. | 29709135 |
| Inflammation, Kidney Diseases, Malignant Neoplasms | Altered Intercellular Communication | Cardiovascular, metabolic, neurodegenerative, and renal disorders, and certain cancers are more common in this cohort, which is attributed to elevated rates of inflammation. | 29714407 |
| Unknown (origin) (qualifier value), Ocular Hypotension, Uveal Effusion Syndrome, Inflammation | Altered Intercellular Communication | The uveal effusion syndrome may be idiopathic, although in the majority of patients it is secondary to other ocular conditions, such as hypotony or inflammation. | 29727114 |
| Inflammation, Hernia | Altered Intercellular Communication | Purpose - Since inflammation has an important role in lumbar disc hernias, and RDW, MPV and N/L ratio are also known to be in correlation with inflammation, we have investigated these parameters of the patients with lumbar disc hernias and compared them with the results of the healthy subjects. | 29733559 |
| Inflammation, Primary malignant neoplasm | Altered Intercellular Communication | The results of cervical cytological examination showed that the manner of progression from inflammation to cancer could differ considerably. | 29734556 |
| Inflammation, Atrial Fibrillation by ECG Finding | Altered Intercellular Communication | Low-Level Vagus Nerve Stimulation Suppresses Post-Operative Atrial Fibrillation and Inflammation: A Randomized Study. | 29759717 |
| Inflammation | Altered Intercellular Communication | These data suggest that LLVNS suppresses POAF and attenuates inflammation in patients undergoing cardiac surgery. | 29759717 |
| Giant Cell Arteritis, Inflammation, GCA gene, Vasculitis, CTCAE | Altered Intercellular Communication | Giant cell arteritis (GCA) is a chronic vasculitis, characterized by inflammation of large- and medium-sized arteries, primarily affecting the external carotid artery and its branches, especially the superficial temporal artery. | 29772142 |
| Inflammation, Chronic Obstructive Airway Disease, Sleep Apnea, Obstructive, Reactive Hyperemia | Altered Intercellular Communication | Vascular Responses to Post Occlusive Reactive Hyperemia and Systemic Inflammation in Overlap Syndrome of Chronic Obstructive Pulmonary Disease and Obstructive Sleep Apnea. | 29809373 |
| Inflammation | Altered Intercellular Communication | The patients with Overlap Syndrome have systemic inflammation and impaired reactive hyperaemia response. | 29809373 |
| Inflammation, Gastrointestinal Hemorrhage | Altered Intercellular Communication | Air pollution increases intestinal permeability, alters the gut microbiome, and promotes inflammation, which might contribute towards gastrointestinal bleeding. | 29851584 |
| Inflammation, Systemic Inflammatory Response Syndrome | Altered Intercellular Communication | The role of inflammation was estimated by the incidence of SIRS and the levels of the inflammatory markers. | 29873468 |
| Primary malignant neoplasm, Non-Small Cell Lung Carcinoma | Altered Intercellular Communication | Advanced Lung Cancer Inflammation index: a prognostic score in patients with metastatic non-small cell lung cancer. | 29877556 |
| Inflammation, Primary malignant neoplasm | Altered Intercellular Communication | Recent studies have identified that inflammation had a significant association with cancer development and progression. | 29877556 |
| Primary malignant neoplasm, Non-Small Cell Lung Carcinoma | Altered Intercellular Communication | Inflammation markers have been shown to predict prognosis during cancer including non-small cell lung cancer (NSCLC). | 29878284 |
| Inflammation | Altered Intercellular Communication | The identified proteins are involved in the regulation of inflammation, apoptosis, adhesion and transport of ions and other important biological processes. | 29889369 |
| Inflammation, Infection, Liver diseases | Altered Intercellular Communication | Its levels are not influenced by inflammation, infections, hepatic or renal diseases, or by dietary or constitutional factors. | 29900708 |
| Idiopathic disease, Inflammation, Retractile Mesenteritis | Altered Intercellular Communication | Sclerosing mesenteritis (SM) is a rare idiopathic disorder characterized by chronic non-specific inflammation involving the adipose tissue of the bowel mesentery. | 29963834 |
| Inflammation, Distortion | Altered Intercellular Communication | Their laparoscopic repair still offers challenges, most especially in the presence of inflammation, scarring, and tissue distortion. | 29999297 |
| Inflammation, S100A4 protein, human, Eosinophilic esophagitis, "Extra-osseous Ewings sarcoma", Disease | Altered Intercellular Communication | Eosinophilic esophagitis (EoE) is a disorder characterized by long-term chronic eosinophilic inflammation, which may predispose patients for malignant transformation. | 30052901 |
| Diabetic mastopathy, Inflammatory Breast Carcinoma, Medullary carcinoma | Altered Intercellular Communication | Differential diagnosis of lupus mastitis includes inflammatory breast carcinoma, primary medullary carcinoma, and other immune-mediated inflammatory conditions such as diabetic mastopathy. | 30064607 |
| Inflammation | Altered Intercellular Communication | However, in our opinion, NHD should not be classified as a "neurogenic inflammation". | 30064610 |
| Inflammation, Cardiac sarcoidosis | Altered Intercellular Communication | Characterization of the Electroanatomic Substrate in Cardiac Sarcoidosis: Correlation With Imaging Findings of Scar and Inflammation. | 30089553 |
| Inflammation, Fibrosis Assessment, Cardiac sarcoidosis, Tachycardia, Ventricular | Altered Intercellular Communication | This study sought to characterize the electroanatomic (EAM) substrate in patients with cardiac sarcoidosis (CS) and ventricular tachycardia and its relationship to imaging findings of inflammation and fibrosis. | 30089553 |
| Inflammation, Fibrosis Assessment | Altered Intercellular Communication | CS is characterized by coexistence of active inflammation and replacement fibrosis. | 30089553 |
| Inflammation | Altered Intercellular Communication | Overall, the agreement between the presence of abnormal EGM was higher with the presence of LGE (k = 0.51; p < 0.001) than with the presence of active inflammation (k = -0.12; p = 0.003). | 30089553 |
| Inflammation, Transmural | Altered Intercellular Communication | Abnormal EGM were more likely located in segments with more scar transmurality (LGE) at CMR and a lower degree of inflammation on PET. | 30089553 |
| Schistosomiasis, Necrotizing granulomatous inflammation | Altered Intercellular Communication | Schistosomiasis is a chronic granulomatous inflammation that affects many systems in the body including the gastrointestinal tract. | 30157328 |
| Inflammation, Monoclonal Gammopathy of Undetermined Significance, Amyloidosis | Altered Intercellular Communication | This could be attributed to the following factors : l)the underlying etiology of the AA amyloidosis, which was not clear, 2)a lack of any current evidence of chronic inflammation, and 3) MGUS as the cause of AL amyloidosis. | 30375826 |
| Inflammation, Hemorrhage, Perforation (observation), Specimen Source Codes - Abscess | Altered Intercellular Communication | Peritumorous inflammation with abscess formation was noted in 13,5% cases, hemorrhage - in 5,6% tumor perforation - in 4,1% cases. | 30444098 |